Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/GO_0099140 presynaptic actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0099187 presynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0099143 presynaptic actin cytoskeleton http://purl.obolibrary.org/obo/GO_0015629 actin cytoskeleton The actin cytoskeleton that is part of a presynapse. http://purl.obolibrary.org/obo/UBERON_0036244 secretion of serous membrane http://purl.obolibrary.org/obo/UBERON_0007779 transudate A transudate found in the serous sac. http://purl.obolibrary.org/obo/CHEBI_138103 inorganic acid http://purl.obolibrary.org/obo/CHEBI_39141 Bronsted acid A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water. http://purl.obolibrary.org/obo/GO_0061951 establishment of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane The directed movement of a protein to a specific location in a plasma membrane. http://purl.obolibrary.org/obo/UBERON_0036289 anterior wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0036286 wall of right ventricle Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle. http://purl.obolibrary.org/obo/GO_0120178 steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0006694 steroid biosynthetic process The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0150119 negative regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/GO_0150146 cell junction disassembly http://purl.obolibrary.org/obo/GO_0034330 cell junction organization The disaggregation of a cell junction into its constituent components. http://purl.obolibrary.org/obo/CL_0009097 embryonic skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development. http://purl.obolibrary.org/obo/UBERON_8480001 capillary of brain http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel A capillary that is part of the brain. http://purl.obolibrary.org/obo/UBERON_8480002 thoracic aorta smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004178 aorta smooth muscle tissue A portion of smooth muscle tissue that is part of the thoracic aorta. http://purl.obolibrary.org/obo/GO_0160043 catecholamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/PR_000064867 protein-containing molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity that minimally consists of a protein. http://purl.obolibrary.org/obo/CHEBI_15841 polypeptide http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A peptide containing ten or more amino acid residues. http://purl.obolibrary.org/obo/CHEBI_25512 neurotransmitter http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. http://purl.obolibrary.org/obo/CHEBI_32952 amine http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/CHEBI_33567 catecholamine http://purl.obolibrary.org/obo/CHEBI_25375 monoamine molecular messenger 4-(2-Aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity An organic compound having at least one hydroxy group attached to a carbon atom. http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene. http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms. http://purl.obolibrary.org/obo/CHEBI_5686 heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclic compound having as ring members atoms of at least two different elements. http://purl.obolibrary.org/obo/CHEBI_67079 anti-inflammatory agent http://purl.obolibrary.org/obo/CHEBI_33232 application Any compound that has anti-inflammatory effects. http://purl.obolibrary.org/obo/CHEBI_76967 human xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. http://purl.obolibrary.org/obo/CHEBI_83056 Daphnia magna metabolite http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite A Daphnia metabolite produced by the species Daphnia magna. http://purl.obolibrary.org/obo/CHEBI_84729 hydroxyindoles http://purl.obolibrary.org/obo/CHEBI_24828 indoles Any member of the class of indoles carrying at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_38716 carboxylic acid dianion A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_64049 food acidity regulator http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents. http://purl.obolibrary.org/obo/CHEBI_131927 dicarboxylic acids and O-substituted derivatives http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens. http://purl.obolibrary.org/obo/CHEBI_132153 hyaluronate http://purl.obolibrary.org/obo/CHEBI_63551 carbohydrate acid derivative anion A carbohydrate acid derivative anion obtained by deprotonation of the carboxy groups of hyaluronic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_15366 acetic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A simple monocarboxylic acid containing two carbons. http://purl.obolibrary.org/obo/CHEBI_16336 hyaluronic acid http://purl.obolibrary.org/obo/CHEBI_72813 exopolysaccharide A mucopolysaccharide composed of N-acetylglucosamine and glucuronic acid subunits. It is found in the connective tissues of vertebrates. A principal constituent of the extracellular matrix (ECM), it mediates the growth and metastasis of tumour cells. http://purl.obolibrary.org/obo/CHEBI_16765 tryptamine http://purl.obolibrary.org/obo/CHEBI_64365 aralkylamino compound An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position. http://purl.obolibrary.org/obo/CHEBI_18059 lipid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. http://purl.obolibrary.org/obo/CHEBI_23357 cofactor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). http://purl.obolibrary.org/obo/CHEBI_24533 heterodetic cyclic peptide http://purl.obolibrary.org/obo/CHEBI_23449 cyclic peptide A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond. http://purl.obolibrary.org/obo/CHEBI_24833 oxoacid http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/CHEBI_25367 molecule http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity Any polyatomic entity that is an electrically neutral entity consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_25696 organic anion http://purl.obolibrary.org/obo/CHEBI_25699 organic ion Any organic ion with a net negative charge. http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion http://purl.obolibrary.org/obo/CHEBI_51151 dipolar compound A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer). http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated. http://purl.obolibrary.org/obo/CHEBI_30089 acetate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_24433 group Any substituent group or skeleton containing carbon. http://purl.obolibrary.org/obo/CHEBI_33708 amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33247 organic group When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue. http://purl.obolibrary.org/obo/CHEBI_33893 reagent http://purl.obolibrary.org/obo/CHEBI_33232 application A substance used in a chemical reaction to detect, measure, examine, or produce other substances. http://purl.obolibrary.org/obo/CHEBI_35222 inhibitor http://purl.obolibrary.org/obo/CHEBI_24432 biological role A substance that diminishes the rate of a chemical reaction. http://purl.obolibrary.org/obo/CHEBI_35223 catalyst http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction. http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group. http://purl.obolibrary.org/obo/CHEBI_36587 organic oxo compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element. http://purl.obolibrary.org/obo/CHEBI_47622 acetate ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any carboxylic ester where the carboxylic acid component is acetic acid. http://purl.obolibrary.org/obo/CHEBI_47891 steroid acid http://purl.obolibrary.org/obo/CHEBI_64709 organic acid Any steroid substituted by at least one carboxy group. http://purl.obolibrary.org/obo/CHEBI_48356 protic solvent http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent A polar solvent that is capable of acting as a hydron (proton) donor. http://purl.obolibrary.org/obo/CHEBI_48705 agonist http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. http://purl.obolibrary.org/obo/CHEBI_50160 steroid acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion Any anion formed by loss of a proton from a steroid acid. http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A biological role played by the molecular entity or part thereof within a biochemical context. http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical http://purl.obolibrary.org/obo/CHEBI_33232 application Any substance introduced into a living organism with therapeutic or diagnostic purpose. http://purl.obolibrary.org/obo/CHEBI_60004 mixture http://purl.obolibrary.org/obo/CHEBI_59999 chemical substance A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind. http://purl.obolibrary.org/obo/CHEBI_60164 ionic polymer http://purl.obolibrary.org/obo/CHEBI_60027 polymer An ionic polymer is a polymer, composed of ionic macromolecules. http://purl.obolibrary.org/obo/CHEBI_61120 nucleobase-containing molecular entity http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene Any compound that has a nucleobase as a part. http://purl.obolibrary.org/obo/CHEBI_61469 polyanionic polymer http://purl.obolibrary.org/obo/CHEBI_60164 ionic polymer A polymer, composed of polyanion macromolecules. http://purl.obolibrary.org/obo/CHEBI_63436 carbohydrate acid derivative http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from a carbohydrate acid. http://purl.obolibrary.org/obo/CHEBI_63551 carbohydrate acid derivative anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative. http://purl.obolibrary.org/obo/CHEBI_64775 organic anionic group http://purl.obolibrary.org/obo/CHEBI_64767 anionic group An anionic group that contains carbon. http://purl.obolibrary.org/obo/CHEBI_64909 poison http://purl.obolibrary.org/obo/CHEBI_24432 biological role Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism. http://purl.obolibrary.org/obo/CHEBI_65212 polysaccharide derivative http://purl.obolibrary.org/obo/CHEBI_167559 glycan A carbohydrate derivative that is any derivative of a polysaccharide. http://purl.obolibrary.org/obo/CHEBI_65255 food preservative http://purl.obolibrary.org/obo/CHEBI_64047 food additive Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes. http://purl.obolibrary.org/obo/CHEBI_65296 primary ammonium ion http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite Any animal metabolite produced during a metabolic reaction in mammals. http://purl.obolibrary.org/obo/CHEBI_78608 alpha-amino-acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion An amino acid-zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_83039 crustacean metabolite http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill. http://purl.obolibrary.org/obo/CHEBI_22221 acyl group http://purl.obolibrary.org/obo/CHEBI_33247 organic group An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids. http://purl.obolibrary.org/obo/CHEBI_22563 anion http://purl.obolibrary.org/obo/CHEBI_24870 ion A monoatomic or polyatomic species having one or more elementary charges of the electron. http://purl.obolibrary.org/obo/CHEBI_22868 bile salt http://purl.obolibrary.org/obo/CHEBI_36078 cholanoid A sodium salt of the conjugate of any bile acid with either glycine or taurine. http://purl.obolibrary.org/obo/CHEBI_23004 carbamoyl group http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid. http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_50906 role A role played by the molecular entity or part thereof within a biological context. http://purl.obolibrary.org/obo/CHEBI_24532 organic heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_33832 organic cyclic compound A cyclic compound having as ring members atoms of carbon and at least of one other element. http://purl.obolibrary.org/obo/CHEBI_24651 hydroxides http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)). http://purl.obolibrary.org/obo/CHEBI_24663 hydroxy-5beta-cholanic acid http://purl.obolibrary.org/obo/CHEBI_36248 5beta-cholanic acids Any member of the class of 5beta-cholanic acids carrying at least one hydroxy group at unspecified position. http://purl.obolibrary.org/obo/CHEBI_24835 inorganic molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity that contains no carbon. http://purl.obolibrary.org/obo/CHEBI_24866 salt http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity A salt is an assembly of cations and anions. http://purl.obolibrary.org/obo/CHEBI_24870 ion http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity having a net electric charge. http://purl.obolibrary.org/obo/CHEBI_25741 oxide http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity An oxide is a chemical compound of oxygen with other chemical elements. http://purl.obolibrary.org/obo/CHEBI_26714 sodium salt http://purl.obolibrary.org/obo/CHEBI_35479 alkali metal salt Any alkali metal salt having sodium(1+) as the cation. http://purl.obolibrary.org/obo/CHEBI_26764 steroid hormone http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Any steroid that acts as hormone. http://purl.obolibrary.org/obo/CHEBI_26820 sulfates http://purl.obolibrary.org/obo/CHEBI_37826 sulfuric acid derivative Salts and esters of sulfuric acid http://purl.obolibrary.org/obo/CHEBI_26932 tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_38077 polypyrrole A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. http://purl.obolibrary.org/obo/CHEBI_28087 glycogen http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A polydisperse, highly branched glucan composed of chains of D-glucopyranose residues in alpha(1->4) glycosidic linkage, joined together by alpha(1->6) glycosidic linkages. A small number of alpha(1->3) glycosidic linkages and some cumulative alpha(1->6) links also may occur. The branches in glycogen typically contain 8 to 12 glucose residues. http://purl.obolibrary.org/obo/CHEBI_29101 sodium(1+) http://purl.obolibrary.org/obo/CHEBI_37246 elemental sodium A monoatomic monocation obtained from sodium. http://purl.obolibrary.org/obo/CHEBI_32988 amide http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/CHEBI_33232 application http://purl.obolibrary.org/obo/CHEBI_50906 role Intended use of the molecular entity or part thereof by humans. http://purl.obolibrary.org/obo/CHEBI_33238 monoatomic entity http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity A monoatomic entity is a molecular entity consisting of a single atom. http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_37175 organic hydride An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system. http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A chemical entity constituting the smallest component of an element having the chemical properties of the element. http://purl.obolibrary.org/obo/CHEBI_33253 nucleon http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle Heavy nuclear particle: proton or neutron. http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity all atoms of which have the same atomic number. http://purl.obolibrary.org/obo/CHEBI_33285 heteroorganic entity http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms. http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity A molecular entity containing one or more atoms of an alkali metal. http://purl.obolibrary.org/obo/CHEBI_33300 pnictogen http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth. http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity A p-block molecular entity containing any pnictogen. http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom Any p-block element belonging to the group 16 family of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity Any p-block molecular entity containing a chalcogen. http://purl.obolibrary.org/obo/CHEBI_33318 main group element atom http://purl.obolibrary.org/obo/CHEBI_33250 atom An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33521 metal atom http://purl.obolibrary.org/obo/CHEBI_33250 atom An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity. http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_33318 main group element atom Any main group element atom belonging to the p-block of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity A main group molecular entity that contains one or more atoms of a p-block element. http://purl.obolibrary.org/obo/CHEBI_33832 organic cyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound Any organic molecule that consists of atoms connected in the form of a ring. http://purl.obolibrary.org/obo/CHEBI_33937 macronutrient http://purl.obolibrary.org/obo/CHEBI_33284 nutrient Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals. http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion http://purl.obolibrary.org/obo/CHEBI_33273 polyatomic anion An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen. http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. http://purl.obolibrary.org/obo/CHEBI_36248 5beta-cholanic acids http://purl.obolibrary.org/obo/CHEBI_136889 5beta steroid Members of the class of cholanic acids based on a 5beta-cholane skeleton. http://purl.obolibrary.org/obo/CHEBI_36277 bile acid salt http://purl.obolibrary.org/obo/CHEBI_36078 cholanoid A salt of a bile acid. http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity Any molecular entity consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_36358 polyatomic ion http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity An ion consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_24870 ion A monoatomic or polyatomic species having one or more elementary charges of the proton. http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity An organochalcogen compound is a compound containing at least one carbon-chalcogen bond. http://purl.obolibrary.org/obo/CHEBI_37164 homopolysaccharide http://purl.obolibrary.org/obo/CHEBI_18154 polysaccharide Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'. http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity A molecular entity consisting of two or more chemical elements. http://purl.obolibrary.org/obo/CHEBI_37838 carboacyl group http://purl.obolibrary.org/obo/CHEBI_22221 acyl group A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_39141 Bronsted acid http://purl.obolibrary.org/obo/CHEBI_37527 acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). http://purl.obolibrary.org/obo/CHEBI_51422 organodiyl group http://purl.obolibrary.org/obo/CHEBI_51446 organic divalent group Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s). http://purl.obolibrary.org/obo/CHEBI_63534 monoamine http://purl.obolibrary.org/obo/CHEBI_64365 aralkylamino compound An aralylamino compound which contains one amino group connected to an aromatic ring by a two-carbon chain. Monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes. http://purl.obolibrary.org/obo/CHEBI_39142 Bronsted base http://purl.obolibrary.org/obo/CHEBI_22695 base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). http://purl.obolibrary.org/obo/CHEBI_39144 Lewis base http://purl.obolibrary.org/obo/CHEBI_22695 base A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct. http://purl.obolibrary.org/obo/CHEBI_73398 indole skeleton http://purl.obolibrary.org/obo/CHEBI_73541 organic heterobicyclic ring A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring. http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A role played by the molecular entity or part thereof which causes the development of a pathological process. http://purl.obolibrary.org/obo/CHEBI_73541 organic heterobicyclic ring http://purl.obolibrary.org/obo/CHEBI_52845 cyclic organic group A bicyclic organic group that contains both carbon and hetero atoms. http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite http://purl.obolibrary.org/obo/CHEBI_83039 crustacean metabolite A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia http://purl.obolibrary.org/obo/PR_000014841 sonic hedgehog protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000016043 T-cell acute lymphocytic leukemia protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_P01308 insulin gene translation product (human) http://purl.obolibrary.org/obo/PR_000009054 insulin gene translation product An insulin gene translation product that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P13591 neural cell adhesion molecule 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A neural cell adhesion molecule 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P16871 interleukin-7 receptor subunit alpha (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An interleukin-7 receptor subunit alpha that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P25918 B-lymphocyte antigen CD19 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD19 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P28906 hematopoietic progenitor cell antigen CD34 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD34 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/UBERON_0035819 abdominopelvic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity. http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process One of the two nuclear divisions that occur as part of the meiotic cell cycle. http://purl.obolibrary.org/obo/CHEBI_136889 5beta steroid http://purl.obolibrary.org/obo/CHEBI_35341 steroid Any steroid that has beta-configuration at position 5. http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering http://purl.obolibrary.org/obo/GO_0051640 organelle localization The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. http://purl.obolibrary.org/obo/GO_0150063 visual system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. http://purl.obolibrary.org/obo/GO_0140734 ammonium excretion http://purl.obolibrary.org/obo/GO_0007588 excretion The elimination of ammonium ions from an excretory cell. http://purl.obolibrary.org/obo/UBERON_8440015 noradrenergic cell groups http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter norepinephrine (noradrenalin). http://purl.obolibrary.org/obo/GO_0141187 nucleic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The biosynthetic process resulting in the formation of a nucleic acid. http://purl.obolibrary.org/obo/CL_4052002 syncytial cell http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm. http://purl.obolibrary.org/obo/CL_4052003 intestinal villus capillary endothelial cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell A capillary endothelial cell that is part of the intestinal villus. This cell is highly fenestrated, with fenestrations most numerous at the villus tips, and plays a vital role in nutrient absorption and maintaining the selective permeability of the intestinal barrier. http://purl.obolibrary.org/obo/CL_4052006 intestinal enteroendocrine progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell An epithelial cell that is part of the crypt of Lieberkuhn, originating from intestinal stem cells and giving rise to enteroendocrine cells (EECs). In mouse and human, this cell can be characterized by the expression of Neurog3, and has the ability to proliferate and differentiate into multiple EEC subtypes. Its proliferative potential contributes to crypt growth, distinguishing it from fully differentiated EECs. http://purl.obolibrary.org/obo/PATO_0000001 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities http://purl.obolibrary.org/obo/PATO_0000025 composition http://purl.obolibrary.org/obo/PATO_0000141 structure A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts. http://purl.obolibrary.org/obo/PATO_0000051 morphology http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. http://purl.obolibrary.org/obo/PATO_0000052 shape http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). http://purl.obolibrary.org/obo/PATO_0000136 closure http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent. http://purl.obolibrary.org/obo/PATO_0000141 structure http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form. http://purl.obolibrary.org/obo/PATO_0000150 texture http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics. http://purl.obolibrary.org/obo/PATO_0000261 maturity http://purl.obolibrary.org/obo/PATO_0001995 organismal quality A quality of a single physical entity which is held by a bearer when the latter exhibits a state of growth, differentiation, or development. http://purl.obolibrary.org/obo/PATO_0000402 branched http://purl.obolibrary.org/obo/PATO_0002009 branchiness A branchiness quality inhering in a bearer by virtue of the bearer's having branches. http://purl.obolibrary.org/obo/PATO_0000407 flat http://purl.obolibrary.org/obo/PATO_0002254 flattened A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature. http://purl.obolibrary.org/obo/PATO_0000411 circular http://purl.obolibrary.org/obo/PATO_0000947 elliptic A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center. http://purl.obolibrary.org/obo/PATO_0000608 closed http://purl.obolibrary.org/obo/PATO_0000136 closure A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view. http://purl.obolibrary.org/obo/PATO_0000947 elliptic http://purl.obolibrary.org/obo/PATO_0002318 superelliptic A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section. http://purl.obolibrary.org/obo/PATO_0000957 opacity http://purl.obolibrary.org/obo/PATO_0001300 optical quality An optical quality which obtains by virtue of the ability of the bearer to absorb visible light. http://purl.obolibrary.org/obo/PATO_0000963 opaque http://purl.obolibrary.org/obo/PATO_0000957 opacity A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy. http://purl.obolibrary.org/obo/PATO_0000964 transparent http://purl.obolibrary.org/obo/PATO_0000957 opacity A optical quality inhering in a bearer by virtue of the bearer's lacking opacity. http://purl.obolibrary.org/obo/PATO_0000992 viscosity http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid A physical quality of a fluid inhering in a bearer by virtue of the bearer's disposition to internal resistance to flow. http://purl.obolibrary.org/obo/PATO_0000998 viscous http://purl.obolibrary.org/obo/PATO_0000992 viscosity A viscosity quality inhering in a bearer by virtue of the bearer's having viscosity. http://purl.obolibrary.org/obo/PATO_0001018 physical quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities. http://purl.obolibrary.org/obo/PATO_0001031 elasticity http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way. http://purl.obolibrary.org/obo/PATO_0001171 elastic http://purl.obolibrary.org/obo/PATO_0001031 elasticity An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way. http://purl.obolibrary.org/obo/PATO_0001185 larval http://purl.obolibrary.org/obo/PATO_0000261 maturity A maturity quality inhering in a bearer by virtue of the bearer's indirect development, undergoing metamorphosis. http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/PATO_0000001 quality A quality which inheres in a continuant. http://purl.obolibrary.org/obo/PATO_0001300 optical quality http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light. http://purl.obolibrary.org/obo/PATO_0001393 euploid http://purl.obolibrary.org/obo/PATO_0001374 ploidy A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes. http://purl.obolibrary.org/obo/PATO_0001397 cellular potency http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types. http://purl.obolibrary.org/obo/PATO_0001400 unipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to produce only one differentiated cell type. http://purl.obolibrary.org/obo/PATO_0001401 oligopotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity. http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to form multiple differentiated cell types. http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. http://purl.obolibrary.org/obo/PATO_0001410 striated http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel. http://purl.obolibrary.org/obo/PATO_0001579 contractility http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality that is the ability to contract or shrink. http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0000052 shape A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001579 contractility A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted. http://purl.obolibrary.org/obo/PATO_0001735 liquid configuration http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of liquids. http://purl.obolibrary.org/obo/PATO_0001736 solid configuration http://purl.obolibrary.org/obo/PATO_0001546 quality of a solid A physical quality inhering in a bearer by virtue of the bearer's parts having the arrangement which exhibits characteristics of solids. http://purl.obolibrary.org/obo/PATO_0001748 invaginated http://purl.obolibrary.org/obo/PATO_0001857 concave A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave. http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0002005 concavity A shape quality in a bearer by virtue of the bearer's curving inward. http://purl.obolibrary.org/obo/PATO_0001873 cylindrical http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section. http://purl.obolibrary.org/obo/PATO_0001908 multinucleate http://purl.obolibrary.org/obo/PATO_0002505 nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. http://purl.obolibrary.org/obo/PATO_0001987 saccular http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance. http://purl.obolibrary.org/obo/PATO_0001992 cellularity http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer by virtue of the bearer's consisting cells. http://purl.obolibrary.org/obo/PATO_0001993 multicellular http://purl.obolibrary.org/obo/PATO_0001992 cellularity A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell. http://purl.obolibrary.org/obo/PATO_0002005 concavity http://purl.obolibrary.org/obo/PATO_0000052 shape Surface shape that refers to the inward or outward curvature of the surface. http://purl.obolibrary.org/obo/PATO_0002006 2-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity. http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape http://purl.obolibrary.org/obo/PATO_0002266 3-D shape A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave. http://purl.obolibrary.org/obo/PATO_0002009 branchiness http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity. http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas. http://purl.obolibrary.org/obo/PATO_0002039 biconcave http://purl.obolibrary.org/obo/PATO_0001857 concave A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces. http://purl.obolibrary.org/obo/PATO_0002045 dendritic http://purl.obolibrary.org/obo/PATO_0000402 branched A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure. http://purl.obolibrary.org/obo/PATO_0002064 fenestrated http://purl.obolibrary.org/obo/PATO_0000141 structure A structure quality inhering in a bearer by virtue of the bearer's delimited by a surface with holes. http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within. http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions. http://purl.obolibrary.org/obo/PATO_0002124 laminar http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer. http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance http://purl.obolibrary.org/obo/PATO_0001018 physical quality A quality inhering in a bearer by virtue of its constitution. http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical http://purl.obolibrary.org/obo/PATO_0001873 cylindrical A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical. http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0001591 curvature A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. http://purl.obolibrary.org/obo/PATO_0002255 grooved http://purl.obolibrary.org/obo/PATO_0000150 texture Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels. http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 3 dimensional entity. http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002078 hollow A cylindrical shape that is hollow. http://purl.obolibrary.org/obo/PATO_0002309 fiber shaped http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter. http://purl.obolibrary.org/obo/PATO_0002318 superelliptic http://purl.obolibrary.org/obo/PATO_0002006 2-D shape A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt http://purl.obolibrary.org/obo/PATO_0002418 acidophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions. http://purl.obolibrary.org/obo/PATO_0002422 acinar http://purl.obolibrary.org/obo/PATO_0000141 structure Pertaining to the individual parts making up an aggregate fruit like a many-lobed "berry," such as a raspberry. http://purl.obolibrary.org/obo/PATO_0002462 collagenous http://purl.obolibrary.org/obo/PATO_0000025 composition A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen. http://purl.obolibrary.org/obo/PATO_0002468 distensible http://purl.obolibrary.org/obo/PATO_0015008 distensibility A structure quality inhering in a bearer by virtue of the bearer's being capable of swelling or stretching. http://purl.obolibrary.org/obo/PATO_0002478 transversely striated http://purl.obolibrary.org/obo/PATO_0001410 striated A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer. http://purl.obolibrary.org/obo/PATO_0002505 nucleated http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. http://purl.obolibrary.org/obo/PATO_0010001 disconnected http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other. http://purl.obolibrary.org/obo/PATO_0015006 polymeric http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array. http://purl.obolibrary.org/obo/PATO_0015008 distensibility http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a bearer by virtue of the extent to which the bearer is capable of being stretched or swollen. http://purl.obolibrary.org/obo/UBERON_0035539 esophageal artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery Any of several arteries that arise from the aorta and supply blood to the esophagus. http://purl.obolibrary.org/obo/UBERON_0035815 paracardial fat http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat Fat deposits in the mediastinum outside the parietal pericardium . http://purl.obolibrary.org/obo/GO_0061938 protein localization to somatodendritic compartment http://purl.obolibrary.org/obo/GO_0008104 protein localization A process in which a protein is transported to or maintained in a location within the somatodendritic compartment. http://purl.obolibrary.org/obo/GO_0110057 regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0110058 positive regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045603 positive regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0110059 negative regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045602 negative regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content. http://purl.obolibrary.org/obo/CL_0008028 visual system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that is capable of part of some visual perception. http://purl.obolibrary.org/obo/GO_0140352 export from cell http://purl.obolibrary.org/obo/GO_0009987 cellular process The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. http://purl.obolibrary.org/obo/GO_0140961 cellular detoxification of metal ion http://purl.obolibrary.org/obo/GO_1990748 cellular detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a metal ion. http://purl.obolibrary.org/obo/UBERON_8600017 bronchopulmonary segment http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A discrete anatomical unit of the lung that is composed of a segmental bronchus and the lung tissue supplied by that bronchus. A bronchopulmonary segment exhibits a pyramidal shape, with its apex pointing towards the center of the lung and its base toward the pleural surface. http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules. http://purl.obolibrary.org/obo/CL_4033093 limbal epithelial stem cell of cornea http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023). http://purl.obolibrary.org/obo/CL_4047023 intestinal lamina propria fibroblast http://purl.obolibrary.org/obo/CL_0000151 secretory cell A fibroblast located in the lamina propria of the intestinal mucosa. This cell expresses PDGFRα and CD81 and is negative for α-smooth muscle actin (α-SMA). This cell is predominantly located in the small intestine adjacent to myofibroblasts surrounding the crypts. It is capable of synthesizing extracellular matrix components and structural proteins such as collagen and elastin. http://purl.obolibrary.org/obo/CL_4047025 type G cell of stomach http://purl.obolibrary.org/obo/CL_1000222 stomach neuroendocrine cell Any type G enteroendocrine cell that is part of some epithelium of stomach. http://purl.obolibrary.org/obo/CL_4052014 pancreatic islet capillary endothelial cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell A capillary endothelial cell that is part of islet of Langerhans, characterized by a high density of fenestrations —approximately ten times greater than those in exocrine pancreatic capillaries. These fenestrations facilitate efficient hormone exchange, which is essential for maintaining glucose homeostasis. The cell's structure and function are regulated by the local production of vascular endothelial growth factor-A (VEGF-A), which maintains its fenestrated architecture. http://purl.obolibrary.org/obo/CL_4052015 endocrine gland capillary endothelial cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell Any capillary endothelial cell that is part of an endocrine gland. http://purl.obolibrary.org/obo/CL_4052030 adventitial fibroblast http://purl.obolibrary.org/obo/CL_0002503 adventitial cell A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression http://purl.obolibrary.org/obo/UBERON_0000017 exocrine pancreas http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The head is the anterior-most division of the body [GO]. http://purl.obolibrary.org/obo/UBERON_0000304 tendon sheath http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath. http://purl.obolibrary.org/obo/UBERON_0000474 female reproductive system http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system The organs and associated structures associated with bearing offspring in a female animal. http://purl.obolibrary.org/obo/UBERON_0000915 thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Subdivision of trunk that lies between the head and the abdomen. http://purl.obolibrary.org/obo/UBERON_0000947 aorta http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation. http://purl.obolibrary.org/obo/UBERON_0000974 neck http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column. http://purl.obolibrary.org/obo/UBERON_0000991 gonad http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ Reproductive organ that produces and releases eggs (ovary) or sperm (testis). http://purl.obolibrary.org/obo/UBERON_0001003 skin epidermis http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outer epithelial layer of the skin that is superficial to the dermis. http://purl.obolibrary.org/obo/UBERON_0001007 digestive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. http://purl.obolibrary.org/obo/UBERON_0001008 renal system http://purl.obolibrary.org/obo/UBERON_8450002 excretory system The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]. http://purl.obolibrary.org/obo/UBERON_0001161 body of stomach http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]. http://purl.obolibrary.org/obo/UBERON_0001173 biliary tree http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder. http://purl.obolibrary.org/obo/UBERON_0001174 common bile duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The part of the biliary tree formed by the union of the cystic duct and the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0001264 pancreas http://purl.obolibrary.org/obo/UBERON_0002075 viscus An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO]. http://purl.obolibrary.org/obo/UBERON_0001456 face http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc). http://purl.obolibrary.org/obo/UBERON_0001585 anterior vena cava http://purl.obolibrary.org/obo/UBERON_0004087 vena cava A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel Any of the tubular branching vessels that carry blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/UBERON_0001645 trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw). http://purl.obolibrary.org/obo/UBERON_0001679 ethmoid bone http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone A bone in the skull that separates the nasal cavity from the brain. As such, it is located at the roof of the nose, between the two orbits. The cubical bone is lightweight due to a spongy construction. The ethmoid bone is one of the bones that makes up the orbit of the eye[WP]. http://purl.obolibrary.org/obo/UBERON_0001768 uvea http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]. http://purl.obolibrary.org/obo/UBERON_0001769 iris http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye. http://purl.obolibrary.org/obo/UBERON_0001775 ciliary body http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes. http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord. http://purl.obolibrary.org/obo/UBERON_0001834 upper lip http://purl.obolibrary.org/obo/UBERON_0001833 lip Lip that covers the upper portion of the mouth.[TAO]. http://purl.obolibrary.org/obo/UBERON_0001835 lower lip http://purl.obolibrary.org/obo/UBERON_0001833 lip Lip that covers the lower portion of the mouth.[TAO]. http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]. http://purl.obolibrary.org/obo/UBERON_0002067 dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. http://purl.obolibrary.org/obo/UBERON_0002348 epicardium http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart. http://purl.obolibrary.org/obo/UBERON_0002349 myocardium http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue The middle layer of the heart, comprised mainly of striated cardiac muscle fibers. http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow http://purl.obolibrary.org/obo/UBERON_0000479 tissue The soft tissue that fills the cavities of bones. http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. http://purl.obolibrary.org/obo/UBERON_0002390 hematopoietic system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Anatomical system that is involved in the production of hematopoietic cells. http://purl.obolibrary.org/obo/UBERON_0003129 skull http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]. http://purl.obolibrary.org/obo/UBERON_0003687 foramen magnum http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP]. http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of: the common carotid artery, or its branches, the external and internal carotid arteries. http://purl.obolibrary.org/obo/UBERON_0007329 pancreatic duct http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A duct that collects and carries secretions of the exocrine pancreas to the intestine. http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]. http://purl.obolibrary.org/obo/UBERON_0007798 vascular system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of all blood and lymph vessels. http://purl.obolibrary.org/obo/UBERON_0016490 auditory system http://purl.obolibrary.org/obo/UBERON_0007037 mechanosensory system Is the sensory system for the sense of hearing. http://purl.obolibrary.org/obo/UBERON_0018707 bladder organ http://purl.obolibrary.org/obo/UBERON_0009856 sac A membranous sac in animals that serves as the receptacle of a liquid or contains gas. http://purl.obolibrary.org/obo/BFO_0000002 continuant http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that has temporal parts and that happens, unfolds or develops through time. http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data item Data about an ontology part is a data item about a part of an ontology, for example a term http://purl.obolibrary.org/obo/IAO_0000225 obsolescence reason specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000409 denotator type http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part A denotator type indicates how a term should be interpreted from an ontological perspective. http://purl.obolibrary.org/obo/PATO_0001374 ploidy http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism. http://purl.obolibrary.org/obo/PATO_0001375 haploid http://purl.obolibrary.org/obo/PATO_0001393 euploid A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes. http://purl.obolibrary.org/obo/PATO_0001377 polyploid http://purl.obolibrary.org/obo/PATO_0001393 euploid A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes. http://purl.obolibrary.org/obo/PATO_0001396 cellular quality http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality A monadic quality of continuant that exists at the cellular level of organisation. http://purl.obolibrary.org/obo/PATO_0001546 quality of a solid http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable. http://purl.obolibrary.org/obo/PATO_0001547 quality of a gas http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape. http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape. http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality that inheres in an entire organism or part of an organism. http://purl.obolibrary.org/obo/PR_000000001 protein http://purl.obolibrary.org/obo/PR_000018263 amino acid chain An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof. http://purl.obolibrary.org/obo/PR_000001004 CD4 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence. http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. http://purl.obolibrary.org/obo/GO_0140014 mitotic nuclear division http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. http://purl.obolibrary.org/obo/GO_0120039 plasma membrane bounded cell projection morphogenesis http://purl.obolibrary.org/obo/GO_0048858 cell projection morphogenesis The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0030030 cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. http://purl.obolibrary.org/obo/GO_0062013 positive regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0062014 negative regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0120158 positive regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0150052 regulation of postsynapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse. http://purl.obolibrary.org/obo/GO_0120186 negative regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_0150099 neuron-glial cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine. http://purl.obolibrary.org/obo/CL_4033020 mucus secreting cell of trachea gland http://purl.obolibrary.org/obo/CL_4033037 mucus secreting cell of tracheobronchial tree submucosal gland A mucus secreting cell that is part of a submucosal gland of the trachea. http://purl.obolibrary.org/obo/CL_4033022 mucus secreting cell of bronchus submucosal gland http://purl.obolibrary.org/obo/CL_4033037 mucus secreting cell of tracheobronchial tree submucosal gland A mucus secreting cell of a submucosal gland of the bronchus. http://purl.obolibrary.org/obo/GO_0014000 morula development http://purl.obolibrary.org/obo/GO_0009790 embryo development The process whose specific outcome is the progression of the morula over time. The morula is a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/CHEBI_33566 catechols http://purl.obolibrary.org/obo/CHEBI_33570 benzenediols Any compound containing an o-diphenol component. http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated. http://purl.obolibrary.org/obo/CHEBI_64708 one-carbon compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity An organic molecular entity containing a single carbon atom (C1). http://purl.obolibrary.org/obo/CHEBI_75772 Saccharomyces cerevisiae metabolite http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae). http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. http://purl.obolibrary.org/obo/CHEBI_76206 xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced by metabolism of a xenobiotic compound. http://purl.obolibrary.org/obo/CHEBI_15339 acceptor http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity. http://purl.obolibrary.org/obo/CHEBI_15693 aldose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals. http://purl.obolibrary.org/obo/CHEBI_15986 polynucleotide http://purl.obolibrary.org/obo/CHEBI_33695 information biomacromolecule A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues. http://purl.obolibrary.org/obo/CHEBI_16134 ammonia http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms. http://purl.obolibrary.org/obo/CHEBI_16189 sulfate http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid. http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates. http://purl.obolibrary.org/obo/CHEBI_16990 bilirubin IXalpha http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid A member of the class of biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin. http://purl.obolibrary.org/obo/CHEBI_17089 glycoprotein http://purl.obolibrary.org/obo/CHEBI_33837 conjugated protein A compound in which a carbohydrate component is covalently bound to a protein component. http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose An aldohexose used as a source of energy and metabolic intermediate. http://purl.obolibrary.org/obo/CHEBI_17544 hydrogencarbonate http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion The carbon oxoanion resulting from the removal of a proton from carbonic acid. http://purl.obolibrary.org/obo/CHEBI_17891 donor http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity. http://purl.obolibrary.org/obo/CHEBI_18085 glycosaminoglycan http://purl.obolibrary.org/obo/CHEBI_22506 aminoglycan Any polysaccharide containing a substantial proportion of aminomonosaccharide residues. http://purl.obolibrary.org/obo/CHEBI_18154 polysaccharide http://purl.obolibrary.org/obo/CHEBI_167559 glycan A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues. http://purl.obolibrary.org/obo/CHEBI_18282 nucleobase http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound That part of DNA or RNA that may be involved in pairing. http://purl.obolibrary.org/obo/CHEBI_23888 drug http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. http://purl.obolibrary.org/obo/CHEBI_24433 group http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A defined linked collection of atoms or a single atom within a molecular entity. http://purl.obolibrary.org/obo/CHEBI_24621 hormone http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. http://purl.obolibrary.org/obo/CHEBI_25362 elemental molecule http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity A molecule all atoms of which have the same atomic number. http://purl.obolibrary.org/obo/CHEBI_25704 organic sulfate http://purl.obolibrary.org/obo/CHEBI_26820 sulfates Compounds of the general formula SO3HOR where R is an organyl group http://purl.obolibrary.org/obo/CHEBI_25905 peptide hormone http://purl.obolibrary.org/obo/CHEBI_16670 peptide Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine. http://purl.obolibrary.org/obo/CHEBI_26819 sulfuric ester http://purl.obolibrary.org/obo/CHEBI_37826 sulfuric acid derivative An ester of an alcohol and sulfuric acid. http://purl.obolibrary.org/obo/CHEBI_27027 micronutrient http://purl.obolibrary.org/obo/CHEBI_33284 nutrient Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group http://purl.obolibrary.org/obo/CHEBI_37838 carboacyl group A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_28616 carbamic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised. http://purl.obolibrary.org/obo/CHEBI_3098 bile acid http://purl.obolibrary.org/obo/CHEBI_138366 bile acids Any member of a group of hydroxy-5beta-cholanic acids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration. http://purl.obolibrary.org/obo/CHEBI_33249 organyl group http://purl.obolibrary.org/obo/CHEBI_51447 organic univalent group Any organic substituent group, regardless of functional type, having one free valence at a carbon atom. http://purl.obolibrary.org/obo/CHEBI_33252 atomic nucleus http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle A nucleus is the positively charged central portion of an atom, excluding the orbital electrons. http://purl.obolibrary.org/obo/CHEBI_33284 nutrient http://purl.obolibrary.org/obo/CHEBI_78295 food component A nutrient is a food component that an organism uses to survive and grow. http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid http://purl.obolibrary.org/obo/CHEBI_15986 polynucleotide A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid. http://purl.obolibrary.org/obo/CHEBI_33709 amino acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid A carboxylic acid containing one or more amino groups. http://purl.obolibrary.org/obo/CHEBI_35107 azane http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride Saturated acyclic nitrogen hydrides having the general formula NnHn+2. http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups. http://purl.obolibrary.org/obo/CHEBI_35524 sympathomimetic agent http://purl.obolibrary.org/obo/CHEBI_37962 adrenergic agent A drug that mimics the effects of stimulating postganglionic adrenergic sympathetic nerves. Included in this class are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. http://purl.obolibrary.org/obo/CHEBI_36080 protein http://purl.obolibrary.org/obo/CHEBI_33695 information biomacromolecule A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome. http://purl.obolibrary.org/obo/CHEBI_36735 biladienes http://purl.obolibrary.org/obo/CHEBI_25046 linear tetrapyrrole Compounds based on a biladiene skeleton. http://purl.obolibrary.org/obo/CHEBI_37527 acid http://purl.obolibrary.org/obo/CHEBI_51086 chemical role An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). http://purl.obolibrary.org/obo/CHEBI_38324 cholinergic agonist http://purl.obolibrary.org/obo/CHEBI_38323 cholinergic drug Any drug that binds to and activates cholinergic receptors. http://purl.obolibrary.org/obo/CHEBI_50910 neurotoxin http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A poison that interferes with the functions of the nervous system. http://purl.obolibrary.org/obo/CHEBI_51086 chemical role http://purl.obolibrary.org/obo/CHEBI_50906 role A role played by the molecular entity or part thereof within a chemical context. http://purl.obolibrary.org/obo/CHEBI_58942 cationic amino-acid residue http://purl.obolibrary.org/obo/CHEBI_64769 organic cationic group An amino-acid residue protonated on nitrogen. http://purl.obolibrary.org/obo/CHEBI_58958 organosulfate oxoanion http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion An organic anion of general formula RS(=O)2O(-) where R is an organyl group. http://purl.obolibrary.org/obo/CHEBI_59252 linear tetrapyrrole anion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion arising from deprotonation of a acyclic tetrapyrrole compound. http://purl.obolibrary.org/obo/CHEBI_59740 nucleophilic reagent http://purl.obolibrary.org/obo/CHEBI_39144 Lewis base A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons. http://purl.obolibrary.org/obo/CHEBI_60242 monovalent inorganic cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one. http://purl.obolibrary.org/obo/CHEBI_60466 peptide zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged. http://purl.obolibrary.org/obo/CHEBI_63248 oxidising agent http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance that removes electrons from another reactant in a redox reaction. http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds. http://purl.obolibrary.org/obo/CHEBI_64769 organic cationic group http://purl.obolibrary.org/obo/CHEBI_64766 cationic group A cationic group that contains carbon. http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any molecule that consists of at least one carbon atom as part of the electrically neutral entity. http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*). http://purl.obolibrary.org/obo/CHEBI_77941 EC 3.5.1.4 (amidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4). http://purl.obolibrary.org/obo/CHEBI_77974 food packaging gas http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that is a (generally inert) gas which is used to envelop foodstuffs during packing and so protect them from unwanted chemical reactions such as food spoilage or oxidation during subsequent transport and storage. The term includes propellant gases, used to expel foods from a container. http://purl.obolibrary.org/obo/CHEBI_78675 fundamental metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced by all living cells. http://purl.obolibrary.org/obo/CHEBI_79388 divalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of two. http://purl.obolibrary.org/obo/CHEBI_29340 hydridonitrate(2-) http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride A divalent inorganic anion resulting from the removal of two protons from ammonia. http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_24433 group Any substituent group which does not contain carbon. http://purl.obolibrary.org/obo/CHEBI_33702 polyatomic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation A cation consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_350546 serotonin(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An ammonium ion that is the conjugate acid of serotonin; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_36341 boson http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle Particle of integer spin quantum number following Bose-Einstein statistics. Bosons are named after Satyendra Nath Bose. http://purl.obolibrary.org/obo/CHEBI_37886 adrenergic agonist http://purl.obolibrary.org/obo/CHEBI_37962 adrenergic agent An agent that selectively binds to and activates adrenergic receptors. http://purl.obolibrary.org/obo/CHEBI_38716 carboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion Any dianion containing at least one carboxy group. http://purl.obolibrary.org/obo/CHEBI_50313 onium cation http://purl.obolibrary.org/obo/CHEBI_50312 onium compound Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families. http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*). http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. http://purl.obolibrary.org/obo/CL_0000005 neural crest derived fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is derived from the neural crest. http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception. http://purl.obolibrary.org/obo/CL_0000007 early embryonic cell (metazoa) http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell found in the embryo before the formation of all the gem layers is complete. http://purl.obolibrary.org/obo/CL_0000008 migratory cranial neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/CL_0000011 migratory trunk neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/CL_0000014 germ line stem cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell A stem cell that is the precursor of gametes. http://purl.obolibrary.org/obo/CL_0000021 female germ cell http://purl.obolibrary.org/obo/CL_0000586 germ cell Female germ cell is a germ cell that supports female gamete production. http://purl.obolibrary.org/obo/CL_0000022 female germ line stem cell http://purl.obolibrary.org/obo/CL_0000021 female germ cell A stem cell that is the precursor of female gametes. http://purl.obolibrary.org/obo/CL_0000023 oocyte http://purl.obolibrary.org/obo/CL_0000021 female germ cell A female germ cell that has entered meiosis. http://purl.obolibrary.org/obo/CL_0000024 oogonial cell http://purl.obolibrary.org/obo/CL_0000021 female germ cell An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. http://purl.obolibrary.org/obo/CL_0000025 egg cell http://purl.obolibrary.org/obo/CL_0000675 female gamete A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. http://purl.obolibrary.org/obo/CL_0000027 smooth muscle cell neural crest derived http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell derived from the neural crest. http://purl.obolibrary.org/obo/CL_0000029 neural crest derived neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that develops from some migratory neural crest cell. http://purl.obolibrary.org/obo/CL_0000031 neuroblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that will develop into a neuron often after a migration phase. http://purl.obolibrary.org/obo/CL_0000034 stem cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell that self-renews as well as give rise to a single mature cell type. http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. http://purl.obolibrary.org/obo/CL_0000038 erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A progenitor cell committed to the erythroid lineage. http://purl.obolibrary.org/obo/CL_0000039 germ line cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell that can give rise to multiple lineages of cells. http://purl.obolibrary.org/obo/CL_0000049 common myeloid progenitor http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. http://purl.obolibrary.org/obo/CL_0000050 megakaryocyte-erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell committed to the megakaryocyte and erythroid lineages. http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell from which all cells of the body can form. http://purl.obolibrary.org/obo/CL_0000055 non-terminally differentiated cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A precursor cell with a limited number of potential fates. http://purl.obolibrary.org/obo/CL_0000056 myoblast http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. http://purl.obolibrary.org/obo/CL_0000057 fibroblast http://purl.obolibrary.org/obo/CL_0000499 stromal cell A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. http://purl.obolibrary.org/obo/CL_0000058 chondroblast http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. http://purl.obolibrary.org/obo/CL_0000064 ciliated cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that has a filiform extrusion of the cell surface. http://purl.obolibrary.org/obo/CL_0000066 epithelial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. http://purl.obolibrary.org/obo/CL_0000067 ciliated epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that has a cilia. http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of a duct. http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree An endothelial cell that lines the vasculature. http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/CL_0000076 squamous epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell Any epithelial cell that is part of some squamous epithelium. http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement. http://purl.obolibrary.org/obo/CL_0000080 circulating cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. http://purl.obolibrary.org/obo/CL_0000081 blood cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell A cell found predominately in the blood. http://purl.obolibrary.org/obo/CL_0000082 epithelial cell of lung http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract An epithelial cell of the lung. http://purl.obolibrary.org/obo/CL_0000083 epithelial cell of pancreas http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the pancreas. http://purl.obolibrary.org/obo/CL_0000098 sensory epithelial cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. http://purl.obolibrary.org/obo/CL_0000099 interneuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. http://purl.obolibrary.org/obo/CL_0000100 motor neuron http://purl.obolibrary.org/obo/CL_0000527 efferent neuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. http://purl.obolibrary.org/obo/CL_0000101 sensory neuron http://purl.obolibrary.org/obo/CL_0000526 afferent neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron whose cell body is within an autonomic ganglion. http://purl.obolibrary.org/obo/CL_0000108 cholinergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that uses acetylcholine as a vesicular neurotransmitter. http://purl.obolibrary.org/obo/CL_0000114 surface ectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024). http://purl.obolibrary.org/obo/CL_0000115 endothelial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. http://purl.obolibrary.org/obo/CL_0000125 glial cell http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. http://purl.obolibrary.org/obo/CL_0000133 neurectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell Ectoderm destined to be nervous tissue. http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. http://purl.obolibrary.org/obo/CL_0000136 adipocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. http://purl.obolibrary.org/obo/CL_0000138 chondrocyte http://purl.obolibrary.org/obo/CL_0000667 collagen secreting cell Skeletogenic cell that is terminally differentiated, secretes an avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. http://purl.obolibrary.org/obo/CL_0000147 pigment cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell A pigment cell is a cell that contains pigment granules. http://purl.obolibrary.org/obo/CL_0000150 glandular secretory epithelial cell http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous. http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that specializes in controlled release of one or more substances. http://purl.obolibrary.org/obo/CL_0000152 exocrine cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct. http://purl.obolibrary.org/obo/CL_0000153 glycosaminoglycan secreting cell http://purl.obolibrary.org/obo/CL_0000447 carbohydrate secreting cell A cell that secretes glycosaminoglycans. http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some protein secretion. http://purl.obolibrary.org/obo/CL_0000163 endocrine cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. http://purl.obolibrary.org/obo/CL_0000164 enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000163 endocrine cell An endocrine cell that is located in the epithelium of the gastrointestinal tract or in the pancreas. http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A neuron that is capable of some hormone secretion in response to neuronal signals. http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some peptide hormone secretion. http://purl.obolibrary.org/obo/CL_0000168 insulin secreting cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any secretory cell that is capable of some insulin secretion. http://purl.obolibrary.org/obo/CL_0000169 type B pancreatic cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A cell that secretes insulin and is located towards the center of the islets of Langerhans. http://purl.obolibrary.org/obo/CL_0000170 glucagon secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell that secretes glucagon. http://purl.obolibrary.org/obo/CL_0000171 pancreatic A cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A type of enteocrine cell found in the periphery of the islets of Langerhans that secretes glucagon. http://purl.obolibrary.org/obo/CL_0000172 somatostatin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell Any secretory cell that is capable of some somatostatin secretion. http://purl.obolibrary.org/obo/CL_0000173 pancreatic D cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A D cell located in the pancreas. Peripherally placed within the islets like type A cells; contains somatostatin. http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some steroid hormone secretion. http://purl.obolibrary.org/obo/CL_0000182 hepatocyte http://purl.obolibrary.org/obo/CL_0000417 endopolyploid cell The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated. http://purl.obolibrary.org/obo/CL_0000183 contractile cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to shorten. http://purl.obolibrary.org/obo/CL_0000187 muscle cell http://purl.obolibrary.org/obo/CL_0000393 electrically responsive cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is capable of detection of a stimulus involved in sensory perception. http://purl.obolibrary.org/obo/CL_0000206 chemoreceptor cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A cell specialized in detecting light stimuli that are involved in visual perception. http://purl.obolibrary.org/obo/CL_0000211 electrically active cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose function is determined by the generation or the reception of an electric signal. http://purl.obolibrary.org/obo/CL_0000213 lining cell http://purl.obolibrary.org/obo/CL_0000215 barrier cell A cell within an epithelial cell sheet whose main function is to act as an internal or external covering for a tissue or an organism. http://purl.obolibrary.org/obo/CL_0000214 synovial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A cell located in the synovial joint. http://purl.obolibrary.org/obo/CL_0000215 barrier cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to prevent the transport of stuff across compartments. http://purl.obolibrary.org/obo/CL_0000219 motile cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that moves by its own activities. http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the outer of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the middle germ layer of the embryo. http://purl.obolibrary.org/obo/CL_0000223 endodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A cell with more than one nucleus. http://purl.obolibrary.org/obo/CL_0000232 erythrocyte http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell that in taxon some Eukaryota. http://purl.obolibrary.org/obo/CL_0000287 eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell Any photoreceptor cell that is part of some eye. http://purl.obolibrary.org/obo/CL_0000293 structural cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to provide structural support, to provide strength and physical integrity to the organism. http://purl.obolibrary.org/obo/CL_0000300 gamete http://purl.obolibrary.org/obo/CL_0000586 germ cell A mature sexual reproductive cell having a single set of unpaired chromosomes. http://purl.obolibrary.org/obo/CL_0000307 tracheal epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell found in the trachea. http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. http://purl.obolibrary.org/obo/CL_0000319 mucus secreting cell http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell Any cell that is capable of some mucus secretion. http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is specialised to accumulate a particular substance(s). http://purl.obolibrary.org/obo/CL_0000329 oxygen accumulating cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell that is capable of some oxygen transport. http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. http://purl.obolibrary.org/obo/CL_0000335 mesenchyme condensation cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. http://purl.obolibrary.org/obo/CL_0000347 scleral cell http://purl.obolibrary.org/obo/CL_0000293 structural cell A cell of the sclera of the eye. http://purl.obolibrary.org/obo/CL_0000348 choroidal cell of the eye http://purl.obolibrary.org/obo/CL_0000293 structural cell A structural cell that is part of optic choroid. http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that is part of some extraembryonic structure. http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development. http://purl.obolibrary.org/obo/CL_0000352 epiblast cell http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. http://purl.obolibrary.org/obo/CL_0000353 blastoderm cell http://purl.obolibrary.org/obo/CL_0000007 early embryonic cell (metazoa) An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). http://purl.obolibrary.org/obo/CL_0000355 multi-potent skeletal muscle stem cell http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. http://purl.obolibrary.org/obo/CL_0000358 sphincter associated smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of a sphincter. A sphincter is a typically circular muscle that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. http://purl.obolibrary.org/obo/CL_0000359 vascular associated smooth muscle cell http://purl.obolibrary.org/obo/CL_4033054 perivascular cell A smooth muscle cell associated with the vasculature. http://purl.obolibrary.org/obo/CL_0000362 epidermal cell http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the integument (the outer layer of an organism). http://purl.obolibrary.org/obo/CL_0000365 animal zygote http://purl.obolibrary.org/obo/CL_0010017 zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. http://purl.obolibrary.org/obo/CL_0000393 electrically responsive cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell whose function is determined by its response to an electric signal. http://purl.obolibrary.org/obo/CL_0000397 ganglion interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron Any interneuron that has its soma located in some ganglion. http://purl.obolibrary.org/obo/CL_0000404 electrically signaling cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell that initiates an electrical signal and passes that signal to another cell. http://purl.obolibrary.org/obo/CL_0000412 polyploid cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that contains more than two haploid sets of chromosomes. http://purl.obolibrary.org/obo/CL_0000413 haploid cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose nucleus contains a single haploid genome. http://purl.obolibrary.org/obo/CL_0000458 serotonin secreting cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). http://purl.obolibrary.org/obo/CL_0000459 noradrenergic cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. http://purl.obolibrary.org/obo/CL_0000488 visible light photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell A photoreceptor cell that detects visible light. http://purl.obolibrary.org/obo/CL_0000499 stromal cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell of an organ found in the loose connective tissue. http://purl.obolibrary.org/obo/CL_0000502 type D enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000172 somatostatin secreting cell A cell found throughout the gastrointestinal tract and in the pancreas. They secrete somatostatin in both an endocrine and paracrine manner. Somatostatin inhibits gastrin, cholecystokinin, insulin, glucagon, pancreatic enzymes, and gastric hydrochloric acid. A variety of substances which inhibit gastric acid secretion (vasoactive intestinal peptide, calcitonin gene-related peptide, cholecystokinin, beta-adrenergic agonists, and gastric inhibitory peptide) are thought to act by releasing somatostatin. http://purl.obolibrary.org/obo/CL_0000506 enkephalin secreting cell http://purl.obolibrary.org/obo/CL_0000507 endorphin secreting cell An endorphine cell that secretes enkephalin. http://purl.obolibrary.org/obo/CL_0000507 endorphin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes endorphin. http://purl.obolibrary.org/obo/CL_0000508 type G enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000509 gastrin secreting cell An endocrine cell found in the stomach and duodenum and is responsible for the secretion of gastrin and enkephalin. Most abundant in pyloric antrum, pyramidal in form with a narrow apex bearing long microvilli. http://purl.obolibrary.org/obo/CL_0000509 gastrin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that secretes gastrin. http://purl.obolibrary.org/obo/CL_0000513 cardiac muscle myoblast http://purl.obolibrary.org/obo/CL_0010021 cardiac myoblast A precursor cell destined to differentiate into cardiac muscle cell. http://purl.obolibrary.org/obo/CL_0000514 smooth muscle myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast A precursor cell destined to differentiate into smooth muscle myocytes. http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A myoblast that differentiates into skeletal muscle fibers. http://purl.obolibrary.org/obo/CL_0000521 fungal cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that in taxon some Fungi. http://purl.obolibrary.org/obo/CL_0000525 syncytiotrophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. http://purl.obolibrary.org/obo/CL_0000526 afferent neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron which conveys sensory information centrally from the periphery. http://purl.obolibrary.org/obo/CL_0000527 efferent neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. http://purl.obolibrary.org/obo/CL_0000540 neuron http://purl.obolibrary.org/obo/CL_0002319 neural cell The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/CL_0000547 proerythroblast http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0000549 basophilic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0000550 polychromatophilic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0000552 orthochromatic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. http://purl.obolibrary.org/obo/CL_0000553 megakaryocyte progenitor cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). http://purl.obolibrary.org/obo/CL_0000556 megakaryocyte http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release. http://purl.obolibrary.org/obo/CL_0000558 reticulocyte http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. http://purl.obolibrary.org/obo/CL_0000562 nucleate erythrocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An erythrocyte having a nucleus. http://purl.obolibrary.org/obo/CL_0000566 angioblastic mesenchymal cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A mesenchymal stem cell capable of developing into blood vessel endothelium. http://purl.obolibrary.org/obo/CL_0000569 cardiac mesenchymal cell http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. http://purl.obolibrary.org/obo/CL_0000575 corneal epithelial cell http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the cornea. http://purl.obolibrary.org/obo/CL_0000586 germ cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell The reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/CL_0000593 androgen secreting cell http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell A steroid hormone secreting cell that secretes androgen. http://purl.obolibrary.org/obo/CL_0000604 retinal rod cell http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. http://purl.obolibrary.org/obo/CL_0000622 acinar cell http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). http://purl.obolibrary.org/obo/CL_0000630 supporting cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to support other cell types. http://purl.obolibrary.org/obo/CL_0000666 fenestrated endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues. http://purl.obolibrary.org/obo/CL_0000667 collagen secreting cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell An extracellular matrix secreting cell that secretes collagen. http://purl.obolibrary.org/obo/CL_0000670 primordial germ cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. http://purl.obolibrary.org/obo/CL_0000675 female gamete http://purl.obolibrary.org/obo/CL_0000300 gamete A mature sexual reproductive cell of the female germline. http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A non-terminally differentiated cell that is capable of developing into a muscle cell. http://purl.obolibrary.org/obo/CL_0000696 PP cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell that stores and secretes pancreatic polypeptide hormone. http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from neural plate and neural crest. http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell Muscle cell which has as its direct parts myofilaments organized into sarcomeres. http://purl.obolibrary.org/obo/CL_0000738 leukocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000540 neuron The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. http://purl.obolibrary.org/obo/CL_0000763 myeloid cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A immature or mature cell in the lineage leading to and including erythrocytes. http://purl.obolibrary.org/obo/CL_0000765 erythroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A cell of the monocyte, granulocyte, or mast cell lineage. http://purl.obolibrary.org/obo/CL_0000837 hematopoietic multipotent progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell restricted to the myeloid lineage. http://purl.obolibrary.org/obo/CL_0000850 serotonergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases serotonin as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell of a hematopoietic lineage. http://purl.obolibrary.org/obo/CL_0001035 bone cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A connective tissue cell found in bone. http://purl.obolibrary.org/obo/CL_0001060 hematopoietic oligopotent progenitor cell, lineage-negative http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0002031 hematopoietic lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. http://purl.obolibrary.org/obo/CL_0002064 pancreatic acinar cell http://purl.obolibrary.org/obo/CL_1001599 pancreas exocrine glandular cell A secretory cell found in pancreatic acini that secretes digestive enzymes and mucins. This cell is a typical zymogenic cell, have a basal nucleus and basophilic cytoplasm consisting of regular arrays of granular endoplasmic reticulum with mitochondria and dense secretory granules. http://purl.obolibrary.org/obo/CL_0002067 type A enteroendocrine cell http://purl.obolibrary.org/obo/CL_0000170 glucagon secreting cell An enteroendocrine cell that produces glucagon. http://purl.obolibrary.org/obo/CL_0002068 Purkinje myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. http://purl.obolibrary.org/obo/CL_0002072 nodal myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. http://purl.obolibrary.org/obo/CL_0002073 transitional myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes. http://purl.obolibrary.org/obo/CL_0002074 myocardial endocrine cell http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides). http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell derived from endoderm. http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell derived from ectoderm. http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell Epithelial cell derived from mesoderm or mesenchyme. http://purl.obolibrary.org/obo/CL_0002079 pancreatic ductal cell http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas Epithelial cell found in the ducts of the pancreas. This cell type contributes to the high luminal pH. http://purl.obolibrary.org/obo/CL_0002080 pancreatic centro-acinar cell http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas A cubodial epithelial cell that is continuous with the lining of intercalated ducts that drain the acinus. This cell type secretes a high pH solution to aid in activation of zymogens, and can differentiate into endocrine and exocrine pancreatic cell types. http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. http://purl.obolibrary.org/obo/CL_0002087 nongranular leukocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte A leukocyte that lacks granules. http://purl.obolibrary.org/obo/CL_0002088 interstitial cell of Cajal http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell http://purl.obolibrary.org/obo/CL_0001035 bone cell A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. http://purl.obolibrary.org/obo/CL_0002095 hilus cell of ovary http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A cell in the hilum of the ovary that produces androgens. http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stomal cell of the ovary http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell An endothelial cell found in capillaries. http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from general body ectoderm and ectoderm placodes. http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell found in the lining of the stomach. http://purl.obolibrary.org/obo/CL_0002180 mucous cell of stomach http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach An epithelial cell of the stomach. This cell produces mucous. http://purl.obolibrary.org/obo/CL_0002183 stem cell of gastric gland http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. http://purl.obolibrary.org/obo/CL_0002195 hepatic stem cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A stem cell that can give rise to the cells of the liver. The term usually refers to the self-renewing pool of hepatocyte precursors in the adult liver (differently from 'hepatoblast', often used for fetal precursors of hepatocytes). http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract An epithelial cell of the tracheobronchial tree. http://purl.obolibrary.org/obo/CL_0002209 intermediate epitheliocyte http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. http://purl.obolibrary.org/obo/CL_0002222 vertebrate lens cell http://purl.obolibrary.org/obo/CL_0000306 crystallin accumulating cell A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. http://purl.obolibrary.org/obo/CL_0002224 lens epithelial cell http://purl.obolibrary.org/obo/CL_0002222 vertebrate lens cell A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. http://purl.obolibrary.org/obo/CL_0002240 marrow fibroblast http://purl.obolibrary.org/obo/CL_0010001 stromal cell of bone marrow A fibroblast in the bone marrow. http://purl.obolibrary.org/obo/CL_0002242 nucleate cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell containing at least one nucleus. http://purl.obolibrary.org/obo/CL_0002243 smooth muscle cell of sphincter of pupil http://purl.obolibrary.org/obo/CL_0000358 sphincter associated smooth muscle cell A circular smooth muscle cell of the iris, innervated by the ciliary nerves (parasympathetic), and acting to contract the pupil. This muscle cell derives from neuroectoderm. This smooth muscle cell results from transformation of epithelial cells to smooth muscle cells. http://purl.obolibrary.org/obo/CL_0002246 peripheral blood stem cell http://purl.obolibrary.org/obo/CL_0000080 circulating cell A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). http://purl.obolibrary.org/obo/CL_0002250 intestinal crypt stem cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells. http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell of the lining of the esophagus. http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell An epithelial cell of the lining of the large intestine. http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell An epithelial cell of the lining of the small intestine. http://purl.obolibrary.org/obo/CL_0002262 endothelial cell of sinusoid http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver. http://purl.obolibrary.org/obo/CL_0002264 type A cell of stomach http://purl.obolibrary.org/obo/CL_1001517 stomach enteroendocrine cell A type of enteroendocrine cell found in the stomach that secretes glucagon. http://purl.obolibrary.org/obo/CL_0002265 type D cell of colon http://purl.obolibrary.org/obo/CL_0009042 enteroendocrine cell of colon A D cell located in the colon. http://purl.obolibrary.org/obo/CL_0002266 type D cell of small intestine http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine A type D cell of the small intestine. http://purl.obolibrary.org/obo/CL_0002267 type D cell of stomach http://purl.obolibrary.org/obo/CL_1000222 stomach neuroendocrine cell A type D cell found in the stomach. http://purl.obolibrary.org/obo/CL_0002275 pancreatic PP cell http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell A PP cell located in the islets of the pancreas. http://purl.obolibrary.org/obo/CL_0002308 epithelial cell of skin gland http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of a skin gland. http://purl.obolibrary.org/obo/CL_0002319 neural cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is part of the nervous system. http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) http://purl.obolibrary.org/obo/CL_0000000 cell A cell of the embryo. http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell of the bronchus. http://purl.obolibrary.org/obo/CL_0002333 neural crest derived adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte derived from a neural crest cell. http://purl.obolibrary.org/obo/CL_0002350 endocardial cell http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. http://purl.obolibrary.org/obo/CL_0002351 progenitor cell of endocrine pancreas http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell A hematopoietic stem cell that exists during embryogenesis. http://purl.obolibrary.org/obo/CL_0002363 keratocyte http://purl.obolibrary.org/obo/CL_0000005 neural crest derived fibroblast A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate. http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. http://purl.obolibrary.org/obo/CL_0002372 myotube http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development. http://purl.obolibrary.org/obo/CL_0002421 nucleated reticulocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. http://purl.obolibrary.org/obo/CL_0002494 cardiocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell located in the heart, including both muscle and non muscle cells. http://purl.obolibrary.org/obo/CL_0002503 adventitial cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc http://purl.obolibrary.org/obo/CL_0002504 enteric smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell of the intestine. http://purl.obolibrary.org/obo/CL_0002521 subcutaneous adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte that is part of subcutaneous adipose tissue. http://purl.obolibrary.org/obo/CL_0002538 intrahepatic cholangiocyte http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte An epithelial cell of the intrahepatic portion of the bile duct. These cells are flattened or cuboidal in shape, and have a small nuclear-to-cytoplasmic ratio relative to large/extrahepatic cholangiocytes. http://purl.obolibrary.org/obo/CL_0002539 aortic smooth muscle cell http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the aorta. http://purl.obolibrary.org/obo/CL_0002540 mesenchymal stem cell of the bone marrow http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell A mesenchymal stem cell that is part of the bone marrow. http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the vein. http://purl.obolibrary.org/obo/CL_0002547 fibroblast of the aortic adventitia http://purl.obolibrary.org/obo/CL_1000306 fibroblast of tunica adventitia of artery A fibroblast of the aortic adventitia. http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A fibroblast that is part of the heart. http://purl.obolibrary.org/obo/CL_0002551 fibroblast of dermis http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of some dermis. http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of lung. http://purl.obolibrary.org/obo/CL_0002557 fibroblast of pulmonary artery http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of pulmonary artery. http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell of the lining of the intestine. http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of adipose tissue. http://purl.obolibrary.org/obo/CL_0002571 hepatic mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0002195 hepatic stem cell A mesenchymal stem cell of liver. http://purl.obolibrary.org/obo/CL_0002572 vertebral mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0001035 bone cell A mesenchymal stem cell of the vertebrae. http://purl.obolibrary.org/obo/CL_0002574 stromal cell of pancreas http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell of the pancreas. http://purl.obolibrary.org/obo/CL_0002585 retinal blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell A blood vessel endothelial cell that is part of the retina. http://purl.obolibrary.org/obo/CL_0002589 smooth muscle cell of the brachiocephalic vasculature http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the bachiocephalic vasculature. http://purl.obolibrary.org/obo/CL_0002590 smooth muscle cell of the brain vasculature http://purl.obolibrary.org/obo/CL_0002319 neural cell A vascular associated smooth muscle cell of the brain vasculature. http://purl.obolibrary.org/obo/CL_0002591 smooth muscle cell of the pulmonary artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle of the pulmonary artery. http://purl.obolibrary.org/obo/CL_0002595 smooth muscle cell of the subclavian artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the subclavian artery. http://purl.obolibrary.org/obo/CL_0002596 smooth muscle cell of the carotid artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell Smooth muscle cell of the carotid artery. http://purl.obolibrary.org/obo/CL_0002598 bronchial smooth muscle cell http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell Any smooth muscle cell that is part of some bronchus. http://purl.obolibrary.org/obo/CL_0002599 smooth muscle cell of the esophagus http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell of the esophagus. http://purl.obolibrary.org/obo/CL_0002600 smooth muscle cell of trachea http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell A smooth muscle cell of the trachea. http://purl.obolibrary.org/obo/CL_0002610 raphe nuclei neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the raphe nuclei. http://purl.obolibrary.org/obo/CL_0002612 neuron of the ventral spinal cord http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the ventral spinal cord. http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of skin. http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell Any epithelial cell that is part of some lower respiratory tract epithelium. http://purl.obolibrary.org/obo/CL_0002653 squamous endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell A squamous shaped endothelial cell. http://purl.obolibrary.org/obo/CL_0002657 glandular cell of esophagus http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus A glandular epithelial cell of the esophagus. http://purl.obolibrary.org/obo/CL_0002658 glandular cell of the large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine A glandular epithelial cell of the large intestine. http://purl.obolibrary.org/obo/CL_0002659 glandular epithelial cell of stomach http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach A glandular epithelial cell that is part of the stomach. http://purl.obolibrary.org/obo/CL_0002663 myocardial endocrine cell of atrium http://purl.obolibrary.org/obo/CL_0002074 myocardial endocrine cell A myocardial endocrine cell that is part of the atrium. http://purl.obolibrary.org/obo/CL_0002664 cardioblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. http://purl.obolibrary.org/obo/CL_0002672 retinal progenitor cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. http://purl.obolibrary.org/obo/CL_0002676 neural crest derived neuroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A neuroblast derived from a neural crest cell. http://purl.obolibrary.org/obo/CL_0002680 PP cell of intestine http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A PP cell found in intestine. http://purl.obolibrary.org/obo/CL_0005000 spinal cord interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron A CNS interneuron located in the spinal cord. http://purl.obolibrary.org/obo/CL_0005024 somatomotor neuron http://purl.obolibrary.org/obo/CL_0000108 cholinergic neuron A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic. http://purl.obolibrary.org/obo/CL_0005026 hepatoblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell Multi fate stem cell that gives rise to both hepatocytes and cholangiocytes as descendants. The term often refers to fetal precursors of hepatocytes (differently from 'hepatic stem cell', usually applied to the self-renewing pool of hepatocyte precursors in the adult liver). Hepatoblasts may also be endogenous, as some stem cells found in the liver come from the bone marrow via blood circulation. http://purl.obolibrary.org/obo/CL_0007001 skeletogenic cell http://purl.obolibrary.org/obo/CL_0000000 cell Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized). http://purl.obolibrary.org/obo/CL_0007004 premigratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. http://purl.obolibrary.org/obo/CL_0007009 prechondroblast http://purl.obolibrary.org/obo/CL_0000055 non-terminally differentiated cell Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. http://purl.obolibrary.org/obo/CL_0008000 non-striated muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell Any muscle cell in which the fibers are not organised into sarcomeres. http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0002372 myotube A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell A muscle cell that is part of some visceral muscle. http://purl.obolibrary.org/obo/CL_0008008 striated visceral muscle cell http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. http://purl.obolibrary.org/obo/CL_0008009 transversely striated visceral muscle cell http://purl.obolibrary.org/obo/CL_0008008 striated visceral muscle cell A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. http://purl.obolibrary.org/obo/CL_0009000 sensory neuron of spinal nerve http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord. http://purl.obolibrary.org/obo/CL_0009001 compound eye retinal cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Any cell in the compound eye, a light sensing organ composed of ommatidia. http://purl.obolibrary.org/obo/CL_0009004 retinal cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/CL_0010001 stromal cell of bone marrow http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell A stromal cell that is part_of a bone marrow. http://purl.obolibrary.org/obo/CL_0010006 cardiac blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell Any blood vessel endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/CL_0010007 His-Purkinje system cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any cell that is part of some His-Purkinje system. http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Any photoreceptor cell that is part of some camera-type eye. http://purl.obolibrary.org/obo/CL_0010020 cardiac glial cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any glial cell that is part of some heart. http://purl.obolibrary.org/obo/CL_0010021 cardiac myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast Any myoblast that develops into some cardiac muscle cell. http://purl.obolibrary.org/obo/CL_0010022 cardiac neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron that has its soma in the heart. http://purl.obolibrary.org/obo/CL_0011001 spinal cord motor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/CL_0011108 colon epithelial cell http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine Epithelial cell that is part of the colon epithelium. http://purl.obolibrary.org/obo/CL_1000222 stomach neuroendocrine cell http://purl.obolibrary.org/obo/CL_1001517 stomach enteroendocrine cell A specialised neuroendocrine cell located in the gastric mucosa that regulates digestive processes including acid secretion and gut motility. This cell stores hormones in large dense core vesicles and synaptic-like microvesicles. http://purl.obolibrary.org/obo/CL_1000223 pulmonary neuroendocrine cell http://purl.obolibrary.org/obo/CL_1000272 lung secretory cell A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury. http://purl.obolibrary.org/obo/CL_1000272 lung secretory cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any secretory cell that is part of some lung. http://purl.obolibrary.org/obo/CL_1000274 trophectodermal cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange. http://purl.obolibrary.org/obo/CL_1000275 smooth muscle cell of small intestine http://purl.obolibrary.org/obo/CL_0002504 enteric smooth muscle cell A smooth muscle cell that is part of the small intestine. http://purl.obolibrary.org/obo/CL_1000276 smooth muscle fiber of duodenum http://purl.obolibrary.org/obo/CL_1000275 smooth muscle cell of small intestine A smooth muscle cell that is part of the duodenum. http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine http://purl.obolibrary.org/obo/CL_0002504 enteric smooth muscle cell A smooth muscle cell that is part of the large intestine. http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A smooth muscle cell that is part of the colon. http://purl.obolibrary.org/obo/CL_1000285 smooth muscle cell of sigmoid colon http://purl.obolibrary.org/obo/CL_1000280 smooth muscle cell of colon A smooth muscle cell that is part of the sigmoid colon. http://purl.obolibrary.org/obo/CL_1000286 smooth muscle cell of rectum http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A smooth muscle cell that is part of the rectum. http://purl.obolibrary.org/obo/CL_1000303 fibroblast of areolar connective tissue http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the areolar connective tissue. http://purl.obolibrary.org/obo/CL_1000306 fibroblast of tunica adventitia of artery http://purl.obolibrary.org/obo/CL_4052030 adventitial fibroblast A fibroblast that is part of the tunica adventitia of artery. http://purl.obolibrary.org/obo/CL_1000307 fibroblast of dense regular elastic tissue http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the dense regular elastic tissue. http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte http://purl.obolibrary.org/obo/CL_0002494 cardiocyte An adipocyte that is part of the epicardial fat. http://purl.obolibrary.org/obo/CL_1000310 adipocyte of epicardial fat of right ventricle http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte An adipocyte that is part of the epicardial fat of right ventricle. http://purl.obolibrary.org/obo/CL_1000311 adipocyte of epicardial fat of left ventricle http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte An adipocyte that is part of the epicardial fat of left ventricle. http://purl.obolibrary.org/obo/CL_1000330 serous cell of epithelium of trachea http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/CL_1000331 serous cell of epithelium of bronchus http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of bronchus. http://purl.obolibrary.org/obo/CL_1000361 transitional myocyte of interatrial septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A transitional myocyte that is part of the interatrial septum. http://purl.obolibrary.org/obo/CL_1000362 transitional myocyte of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A transitional myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/CL_1000376 Purkinje myocyte of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A Purkinje myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid http://purl.obolibrary.org/obo/CL_0002262 endothelial cell of sinusoid An endothelial cell that is part of the hepatic sinusoid. These cells possess flattened areas containing perforations about 0.1 micrometers in diameter, known as fenestrae. The fenestrae are arranged in groups known as sieve plates. http://purl.obolibrary.org/obo/CL_1000409 myocyte of sinoatrial node http://purl.obolibrary.org/obo/CL_0008009 transversely striated visceral muscle cell A muscle cell that is part of the sinoatrial node. http://purl.obolibrary.org/obo/CL_1000410 myocyte of atrioventricular node http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A muscle cell that is part of the atrioventricular node. http://purl.obolibrary.org/obo/CL_1000412 endothelial cell of arteriole http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the arteriole. http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell A blood vessel endothelial cell that is part of an arterial endothelium. http://purl.obolibrary.org/obo/CL_1000414 endothelial cell of venule http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the venule. http://purl.obolibrary.org/obo/CL_1000415 epithelial cell of gallbladder http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of the gallbladder. http://purl.obolibrary.org/obo/CL_1000428 stem cell of epidermis http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A somatic stem cell that is part of the epidermis. http://purl.obolibrary.org/obo/CL_1000443 ciliary muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the ciliary body. http://purl.obolibrary.org/obo/CL_1000444 mesothelial cell of anterior chamber of eye http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the anterior chamber of eyeball. http://purl.obolibrary.org/obo/CL_1000456 mesothelial cell of parietal peritoneum http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum A mesothelial cell that is part of the parietal peritoneum. http://purl.obolibrary.org/obo/CL_1000457 mesothelial cell of visceral peritoneum http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum A mesothelial cell that is part of the visceral peritoneum. http://purl.obolibrary.org/obo/CL_1000478 transitional myocyte of sinoatrial node http://purl.obolibrary.org/obo/CL_1000409 myocyte of sinoatrial node A transitional myocyte that is part of the sinoatrial node. http://purl.obolibrary.org/obo/CL_1000479 Purkinje myocyte of atrioventricular node http://purl.obolibrary.org/obo/CL_1000410 myocyte of atrioventricular node A Purkinje myocyte that is part of the atrioventricular node. http://purl.obolibrary.org/obo/CL_1000482 myocardial endocrine cell of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A myocardial endocrine cell that is part of the interventricular septum. http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell An epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. They are cuboidal epithelium in the small interlobular bile ducts, but become columnar and mucus secreting in larger bile ducts approaching the porta hepatis and the extrahepatic ducts. http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the peritoneum. http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the pleura. http://purl.obolibrary.org/obo/CL_1000492 mesothelial cell of parietal pleura http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura A mesothelial cell that is part of the parietal pleura. http://purl.obolibrary.org/obo/CL_1000493 mesothelial cell of visceral pleura http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura A mesothelial cell that is part of the visceral pleura. http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas http://purl.obolibrary.org/obo/CL_0000083 epithelial cell of pancreas An epithelial cell of the exocrine pancreas. http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the intestinal tract. http://purl.obolibrary.org/obo/CL_1001517 stomach enteroendocrine cell http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach The various hormone- or neurotransmitter-secreting cells present throughout the mucosa of the stomach. http://purl.obolibrary.org/obo/CL_1001567 lung endothelial cell http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree Any endothelial cell of vascular tree that is part of some lung. http://purl.obolibrary.org/obo/CL_1001568 pulmonary artery endothelial cell http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery Any endothelial cell of vascular tree that is part of some pulmonary artery. http://purl.obolibrary.org/obo/CL_1001572 colon endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell A vascular endothelial cell found in colon blood vessels. http://purl.obolibrary.org/obo/CL_1001576 oral mucosa squamous cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal Squamous cell of oral epithelium. http://purl.obolibrary.org/obo/CL_1001588 colon glandular cell http://purl.obolibrary.org/obo/CL_0011108 colon epithelial cell Glandular cell of colon epithelium. Example: Goblet cells; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/CL_1001589 duodenum secretory cell http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell Glandular cell of duodenal epithelium. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Brunner's gland cell. http://purl.obolibrary.org/obo/CL_1001592 gallbladder glandular cell http://purl.obolibrary.org/obo/CL_1000415 epithelial cell of gallbladder Glandular cell of gallbladder epithelium. http://purl.obolibrary.org/obo/CL_1001595 rectum glandular cell http://purl.obolibrary.org/obo/CL_0002658 glandular cell of the large intestine Glandular cell of rectal epithelium. Example: Goblet cell; enterocytes or absorptive cells; enteroendocrine and M cells. http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine A glandular cell found in the epithelium of the small intestine. Example: Enterocytes, Goblet cells, enteroendocrine cells; Paneth cells; M cells; Somatostatin-secreting Cells (D-cells) . http://purl.obolibrary.org/obo/CL_1001599 pancreas exocrine glandular cell http://purl.obolibrary.org/obo/CL_1001433 epithelial cell of exocrine pancreas Glandular cell of exocrine pancreas epithelium. Example: pancreatic acinar cell, glandular cells in pancreatic canaliculi, glandular cells in pancreatic ducts. http://purl.obolibrary.org/obo/CL_1001609 muscle fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Fibroblast from muscle organ. http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. http://purl.obolibrary.org/obo/UBERON_0000010 peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. http://purl.obolibrary.org/obo/UBERON_0000016 endocrine pancreas http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin. http://purl.obolibrary.org/obo/UBERON_0000020 sense organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is capable of transducing sensory stimulus to the nervous system. http://purl.obolibrary.org/obo/UBERON_0000059 large intestine http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A subdivision of the digestive tract that connects the small intestine to the cloaca or anus. Lacks or has few villi[Kardong]. http://purl.obolibrary.org/obo/UBERON_0000065 respiratory tract http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts. http://purl.obolibrary.org/obo/UBERON_0000159 anal canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit The terminal part of the large intestine, continuous proximally with the rectum and distally terminates with the anus. http://purl.obolibrary.org/obo/UBERON_0000160 intestine http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. http://purl.obolibrary.org/obo/UBERON_0000165 mouth http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). http://purl.obolibrary.org/obo/UBERON_0000167 oral cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present). http://purl.obolibrary.org/obo/UBERON_0000178 blood http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid A fluid that is composed of blood plasma and erythrocytes. http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. http://purl.obolibrary.org/obo/UBERON_0000945 stomach http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0000948 heart http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. http://purl.obolibrary.org/obo/UBERON_0000949 endocrine system http://purl.obolibrary.org/obo/UBERON_0015204 glandular system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. http://purl.obolibrary.org/obo/UBERON_0000955 brain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. http://purl.obolibrary.org/obo/UBERON_0000964 cornea http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure. http://purl.obolibrary.org/obo/UBERON_0000965 lens of camera-type eye http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina. http://purl.obolibrary.org/obo/UBERON_0000966 retina http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/UBERON_0000970 eye http://purl.obolibrary.org/obo/UBERON_0000020 sense organ An organ that detects light. http://purl.obolibrary.org/obo/UBERON_0000977 pleura http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion). http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs concerned with reproduction. http://purl.obolibrary.org/obo/UBERON_0000992 ovary http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ The gonad of a female organism which contains germ cells. http://purl.obolibrary.org/obo/UBERON_0001004 respiratory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Functional system which consists of structures involved in respiration. http://purl.obolibrary.org/obo/UBERON_0001016 nervous system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. http://purl.obolibrary.org/obo/UBERON_0001017 central nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information. http://purl.obolibrary.org/obo/UBERON_0001043 esophagus http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). http://purl.obolibrary.org/obo/UBERON_0001052 rectum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The terminal portion of the intestinal tube, terminating with the anus. http://purl.obolibrary.org/obo/UBERON_0001103 diaphragm http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control. http://purl.obolibrary.org/obo/UBERON_0001130 vertebral column http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]. http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue Muscle tissue that consists primarily of skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0001155 colon http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal. http://purl.obolibrary.org/obo/UBERON_0001159 sigmoid colon http://purl.obolibrary.org/obo/UBERON_0000168 proximal-distal subdivision of colon The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity. http://purl.obolibrary.org/obo/UBERON_0001165 pyloric antrum http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells. http://purl.obolibrary.org/obo/UBERON_0001166 pylorus http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum. http://purl.obolibrary.org/obo/UBERON_0001245 anus http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts. http://purl.obolibrary.org/obo/UBERON_0001558 lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]. http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]. http://purl.obolibrary.org/obo/UBERON_0001677 sphenoid bone http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element An unpaired bone situated at the base of the skull in front of the temporal bone and basilar part of the occipital bone. The sphenoid bone is one of the seven bones that articulate to form the orbit. Its shape somewhat resembles that of a butterfly or bat with its wings extended. http://purl.obolibrary.org/obo/UBERON_0001708 jaw skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which includes upper and lower jaw skeletons. http://purl.obolibrary.org/obo/UBERON_0001776 optic choroid http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]. http://purl.obolibrary.org/obo/UBERON_0001833 lip http://purl.obolibrary.org/obo/UBERON_0003102 surface structure One of the two fleshy folds which surround the opening of the mouth. http://purl.obolibrary.org/obo/UBERON_0001982 capillary http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel Any of the smallest blood vessels connecting arterioles with venules. http://purl.obolibrary.org/obo/UBERON_0002012 pulmonary artery http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.. http://purl.obolibrary.org/obo/UBERON_0002048 lung http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Respiration organ that develops as an outpocketing of the esophagus. http://purl.obolibrary.org/obo/UBERON_0002106 spleen http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera The organ that functions to filter blood and to store red corpuscles and platelets. http://purl.obolibrary.org/obo/UBERON_0002107 liver http://purl.obolibrary.org/obo/UBERON_0006925 digestive system gland An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. http://purl.obolibrary.org/obo/UBERON_0002108 small intestine http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]. http://purl.obolibrary.org/obo/UBERON_0002110 gallbladder http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera An organ that aids digestion and stores bile produced by the liver[WP]. http://purl.obolibrary.org/obo/UBERON_0002114 duodenum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one). http://purl.obolibrary.org/obo/UBERON_0002165 endocardium http://purl.obolibrary.org/obo/UBERON_0005983 heart layer The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. http://purl.obolibrary.org/obo/UBERON_0002185 bronchus http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The upper conducting airways of the lung; these airways arise from the terminus of the trachea. http://purl.obolibrary.org/obo/UBERON_0002204 musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the muscular and skeletal systems. http://purl.obolibrary.org/obo/UBERON_0002240 spinal cord http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). http://purl.obolibrary.org/obo/UBERON_0002298 brainstem http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]. http://purl.obolibrary.org/obo/UBERON_0002330 exocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0002351 sinoatrial node http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]. http://purl.obolibrary.org/obo/UBERON_0002358 peritoneum http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that lines the peritoneal cavity[VHOG,modified]. http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. http://purl.obolibrary.org/obo/UBERON_0002394 bile duct http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine. http://purl.obolibrary.org/obo/UBERON_0002405 immune system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. http://purl.obolibrary.org/obo/UBERON_0002407 pericardium http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0002410 autonomic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]. http://purl.obolibrary.org/obo/UBERON_0002416 integumental system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. http://purl.obolibrary.org/obo/UBERON_0003126 trachea http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]. http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An organ involved in reproduction. http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ A female organ involved in reproduction. http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Anatomical system that has as its parts the heart and blood vessels. http://purl.obolibrary.org/obo/UBERON_0004913 hepatopancreatic ampulla http://purl.obolibrary.org/obo/UBERON_0002394 bile duct A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0005057 immune organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is part of a immune system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005409 alimentary part of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The part of the digestive system that excludes the hepatobiliary system. http://purl.obolibrary.org/obo/UBERON_0006562 pharynx http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. http://purl.obolibrary.org/obo/UBERON_0035549 vasculature of integument http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin. http://purl.obolibrary.org/obo/UBERON_0035551 deep vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin. http://purl.obolibrary.org/obo/UBERON_0035552 deep vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery. http://purl.obolibrary.org/obo/GO_0110110 positive regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_0110111 negative regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_0110113 positive regulation of lipid transporter activity http://purl.obolibrary.org/obo/GO_0032411 positive regulation of transporter activity Any process that increases the frequency, rate, or extent of lipid transporter activity. http://purl.obolibrary.org/obo/GO_0150105 protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction A process in which a protein is transported to, or maintained, in a location within a cell-cell junction. http://purl.obolibrary.org/obo/GO_0120305 regulation of pigmentation http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism. http://purl.obolibrary.org/obo/ECAO_0000680 very late organogenesis stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo displays prominent right and left anterior coelomic pouches, and the posterior enterocoel has enlarged. Pronounced cardiac and developing pyloric constrictions (separating respectively the foregut and midgut, and the midgut and hindgut) are formed, and the gut is thus visibly tripartite, with the posterior enterocoel projecting from the developing stomach (former midgut). The wall of the left anterior coelom is distended at both its anterior and posterior margins, where strands of cells extend to the ectoderm. Muscle bands surrounding the esophagus are apparent. Ridges of thickened ectoderm mark the positions of the future ciliary bands. http://purl.obolibrary.org/obo/ECAO_0000690 mesenchyme blastula phase http://purl.obolibrary.org/obo/BFO_0000003 occurrent mesenchyme blastula episode http://purl.obolibrary.org/obo/CHEBI_16670 peptide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc. http://purl.obolibrary.org/obo/CHEBI_17087 ketone http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H). http://purl.obolibrary.org/obo/CHEBI_18357 (R)-noradrenaline http://purl.obolibrary.org/obo/CHEBI_33569 noradrenaline The R-enantiomer of noradrenaline. http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. http://purl.obolibrary.org/obo/CHEBI_22586 antioxidant http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. http://purl.obolibrary.org/obo/CHEBI_24828 indoles http://purl.obolibrary.org/obo/CHEBI_22728 benzopyrrole Any compound containing an indole skeleton. http://purl.obolibrary.org/obo/CHEBI_25212 metabolite http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid An oxoacid containing a single carboxy group. http://purl.obolibrary.org/obo/CHEBI_25697 organic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation Any organic ion with a net positive charge. http://purl.obolibrary.org/obo/CHEBI_27162 tryptamines http://purl.obolibrary.org/obo/CHEBI_24828 indoles Tryptamine and its substitution derivatives. http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_24432 biological role A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester http://purl.obolibrary.org/obo/CHEBI_35701 ester An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion An amino-acid anion obtained by deprotonation of any alpha-amino acid. http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group. http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2). http://purl.obolibrary.org/obo/CHEBI_33853 phenols http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative http://purl.obolibrary.org/obo/CHEBI_33702 polyatomic cation A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc). http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity Any heteroorganic entity containing at least one carbon-nitrogen bond. http://purl.obolibrary.org/obo/CHEBI_35472 anti-inflammatory drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance that reduces or suppresses inflammation. http://purl.obolibrary.org/obo/CHEBI_35620 vasodilator agent http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug A drug used to cause dilation of the blood vessels. http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound An organochalcogen compound containing at least one carbon-oxygen bond. http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide http://purl.obolibrary.org/obo/CHEBI_33256 primary amide An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom. http://purl.obolibrary.org/obo/CHEBI_38325 muscarinic agonist http://purl.obolibrary.org/obo/CHEBI_38324 cholinergic agonist Any drug that binds to and activates a muscarinic cholinergic receptor. http://purl.obolibrary.org/obo/CHEBI_38958 indole alkaloid http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid An alkaloid containing an indole skeleton. http://purl.obolibrary.org/obo/CHEBI_50514 vasoconstrictor agent http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug Drug used to cause constriction of the blood vessels. http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_33582 carbon group molecular entity Any molecular entity that contains carbon. http://purl.obolibrary.org/obo/CHEBI_60027 polymer http://purl.obolibrary.org/obo/CHEBI_60004 mixture A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.. http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals. http://purl.obolibrary.org/obo/CHEBI_75771 mouse metabolite http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). http://purl.obolibrary.org/obo/CHEBI_76924 plant metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. http://purl.obolibrary.org/obo/CHEBI_76971 Escherichia coli metabolite http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. http://purl.obolibrary.org/obo/CHEBI_33655 aromatic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character. http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid containing two carboxy groups. http://purl.obolibrary.org/obo/CHEBI_50994 primary amino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group. http://purl.obolibrary.org/obo/CHEBI_65256 antimicrobial food preservative http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms. http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite http://purl.obolibrary.org/obo/CHEBI_75787 prokaryotic metabolite Any prokaryotic metabolite produced during a metabolic reaction in bacteria. http://purl.obolibrary.org/obo/CHEBI_35287 acylcholine http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion A choline ester formed from choline and a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_53000 epitope http://purl.obolibrary.org/obo/CHEBI_24432 biological role The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. http://purl.obolibrary.org/obo/CHEBI_15355 acetylcholine http://purl.obolibrary.org/obo/CHEBI_35287 acylcholine Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter. http://purl.obolibrary.org/obo/CHEBI_18133 hexose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose). http://purl.obolibrary.org/obo/CHEBI_28790 serotonin http://purl.obolibrary.org/obo/CHEBI_25375 monoamine molecular messenger A primary amino compound that is the 5-hydroxy derivative of tryptamine. http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group. http://purl.obolibrary.org/obo/CHEBI_16541 protein polypeptide chain http://purl.obolibrary.org/obo/CHEBI_15841 polypeptide A naturally occurring polypeptide synthesized at the ribosome. http://purl.obolibrary.org/obo/CHEBI_25375 monoamine molecular messenger http://purl.obolibrary.org/obo/CHEBI_63534 monoamine A group of neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/CHEBI_28938 ammonium http://purl.obolibrary.org/obo/CHEBI_50313 onium cation An onium cation obtained by protonation of ammonia. http://purl.obolibrary.org/obo/CHEBI_33256 primary amide http://purl.obolibrary.org/obo/CHEBI_32988 amide A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/CHEBI_33837 conjugated protein http://purl.obolibrary.org/obo/CHEBI_36080 protein Conjugated protein is a protein that contains a non-peptide component, usually in stoichiometric proportion. http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter. http://purl.obolibrary.org/obo/CHEBI_37395 mucopolysaccharide http://purl.obolibrary.org/obo/CHEBI_18085 glycosaminoglycan Any of the group of polysaccharides composed of alternating units from uronic acids and glycosamines, and commonly partially esterified with sulfuric acid. http://purl.obolibrary.org/obo/CHEBI_37962 adrenergic agent http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. http://purl.obolibrary.org/obo/CHEBI_4167 D-glucopyranose http://purl.obolibrary.org/obo/CHEBI_17634 D-glucose A glucopyranose having D-configuration. http://purl.obolibrary.org/obo/CHEBI_46787 solvent http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A liquid that can dissolve other substances (solutes) without any change in their chemical composition. http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent http://purl.obolibrary.org/obo/CHEBI_46787 solvent A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds. http://purl.obolibrary.org/obo/CHEBI_57887 tryptaminium http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57977 bilirubin(2-) http://purl.obolibrary.org/obo/CHEBI_59252 linear tetrapyrrole anion A dicarboxylic acid dianion obtained by deprotonation of the two carboxy groups of bilirubin; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_64365 aralkylamino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound An organic amino compound in which an aminoalkyl group is linked to an arene. http://purl.obolibrary.org/obo/CHEBI_72813 exopolysaccharide http://purl.obolibrary.org/obo/CHEBI_33694 biomacromolecule A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment. http://purl.obolibrary.org/obo/CHEBI_78295 food component http://purl.obolibrary.org/obo/CHEBI_52211 physiological role A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants. http://purl.obolibrary.org/obo/CHEBI_78433 refrigerant http://purl.obolibrary.org/obo/CHEBI_33232 application A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure. http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of one. http://purl.obolibrary.org/obo/CHEBI_22695 base http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base). http://purl.obolibrary.org/obo/CHEBI_33569 noradrenaline http://purl.obolibrary.org/obo/CHEBI_33567 catecholamine A catecholamine in which C-1 of the aminoethyl side-chain is hydroxy-substituted. http://purl.obolibrary.org/obo/CHEBI_33571 (S)-noradrenaline http://purl.obolibrary.org/obo/CHEBI_33569 noradrenaline The S-enantiomer of noradrenaline. http://purl.obolibrary.org/obo/CHEBI_33694 biomacromolecule http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A macromolecule formed by a living organism. http://purl.obolibrary.org/obo/CHEBI_33697 ribonucleic acid http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins. http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose http://purl.obolibrary.org/obo/CHEBI_18133 hexose A hexose with a (potential) aldehyde group at one end. http://purl.obolibrary.org/obo/CHEBI_35569 alpha-adrenergic agonist http://purl.obolibrary.org/obo/CHEBI_48539 alpha-adrenergic drug An agent that selectively binds to and activates alpha-adrenergic receptors. http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n. http://purl.obolibrary.org/obo/CHEBI_37163 glucan http://purl.obolibrary.org/obo/CHEBI_37164 homopolysaccharide A polysaccharide composed of glucose residues. http://purl.obolibrary.org/obo/CHEBI_4194 D-hexose http://purl.obolibrary.org/obo/CHEBI_18133 hexose A hexose that has D-configuration at position 5. http://purl.obolibrary.org/obo/CHEBI_72587 (R)-noradrenaline(1+) http://purl.obolibrary.org/obo/CHEBI_166902 noradrenaline(1+) An organic cation that is the conjugate acid of (R)-noradrenaline, obtained by protonation of the priamry amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_48539 alpha-adrenergic drug http://purl.obolibrary.org/obo/CHEBI_37962 adrenergic agent Any drug that acts on an alpha-adrenergic receptor. http://purl.obolibrary.org/obo/CHEBI_33233 fundamental particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A particle not known to have substructure. http://purl.obolibrary.org/obo/CHEBI_33273 polyatomic anion http://purl.obolibrary.org/obo/CHEBI_36358 polyatomic ion An anion consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_25367 molecule Any molecule that consists of a series of atoms joined together to form a ring. http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A molecule that features two fused rings. http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound A polycyclic compound in which at least one of the rings contains at least one non-carbon atom. http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element. http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity Hydrides are chemical compounds of hydrogen with other chemical elements. http://purl.obolibrary.org/obo/CHEBI_33710 alpha-amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33708 amino-acid residue An amino-acid residue derived from an alpha-amino acid. http://purl.obolibrary.org/obo/CHEBI_36339 baryon http://purl.obolibrary.org/obo/CHEBI_36344 hadron Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy). http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A nucleus or any of its constituents in any of their energy states. http://purl.obolibrary.org/obo/CHEBI_64709 organic acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity that is acidic and contains carbon in covalent linkage. http://purl.obolibrary.org/obo/CHEBI_59999 chemical substance http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types. http://purl.obolibrary.org/obo/CHEBI_52845 cyclic organic group http://purl.obolibrary.org/obo/CHEBI_33247 organic group An organic group that consists of a closed ring. It may be a substituent or a skeleton. http://purl.obolibrary.org/obo/CHEBI_53309 polyanionic macromolecule http://purl.obolibrary.org/obo/CHEBI_53368 ionic macromolecule A polymer carrying multiple negative charges. http://purl.obolibrary.org/obo/CHEBI_53368 ionic macromolecule http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A macromolecule containing ionic groups. http://purl.obolibrary.org/obo/GO_0005215 transporter activity http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells. http://purl.obolibrary.org/obo/GO_0005275 amine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group. http://purl.obolibrary.org/obo/GO_0005277 acetylcholine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015101 organic cation transmembrane transporter activity Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0005310 dicarboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity Enables the transfer of dicarboxylic acids from one side of a membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups. http://purl.obolibrary.org/obo/GO_0005319 lipid transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Enables the directed movement of lipids into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/GO_0005326 neurotransmitter transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/GO_0005342 organic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of organic acids from one side of a membrane to the other. Organic acids are acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0005575 cellular_component http://purl.obolibrary.org/obo/BFO_0000040 material entity A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). http://purl.obolibrary.org/obo/GO_0005576 extracellular region http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0005577 fibrinogen complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. http://purl.obolibrary.org/obo/GO_0005581 collagen trimer http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. http://purl.obolibrary.org/obo/GO_0005583 fibrillar collagen trimer http://purl.obolibrary.org/obo/GO_0005581 collagen trimer Any triple helical collagen trimer that forms fibrils. http://purl.obolibrary.org/obo/GO_0005585 collagen type II trimer http://purl.obolibrary.org/obo/GO_0005583 fibrillar collagen trimer A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils. http://purl.obolibrary.org/obo/GO_0005587 collagen type IV trimer http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. http://purl.obolibrary.org/obo/GO_0005604 basement membrane http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. http://purl.obolibrary.org/obo/GO_0005615 extracellular space http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. http://purl.obolibrary.org/obo/GO_0005635 nuclear envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport. http://purl.obolibrary.org/obo/GO_0005640 nuclear outer membrane http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. http://purl.obolibrary.org/obo/GO_0005730 nucleolus http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. http://purl.obolibrary.org/obo/GO_0005794 Golgi apparatus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. http://purl.obolibrary.org/obo/GO_0005798 Golgi-associated vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. http://purl.obolibrary.org/obo/GO_0005874 microtubule http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule http://purl.obolibrary.org/obo/GO_0005881 cytoplasmic microtubule A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. http://purl.obolibrary.org/obo/GO_0005880 nuclear microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in the nucleus of a cell. http://purl.obolibrary.org/obo/GO_0005884 actin filament http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. http://purl.obolibrary.org/obo/GO_0005902 microvillus http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction http://purl.obolibrary.org/obo/GO_0070161 anchoring junction A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. http://purl.obolibrary.org/obo/GO_0005929 cilium http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. http://purl.obolibrary.org/obo/GO_0005930 axoneme http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/GO_0005938 cell cortex http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. http://purl.obolibrary.org/obo/GO_0005975 carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0005978 glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolic process The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. http://purl.obolibrary.org/obo/GO_0005979 regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070873 regulation of glycogen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/GO_0005980 glycogen catabolic process http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolic process The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. http://purl.obolibrary.org/obo/GO_0005981 regulation of glycogen catabolic process http://purl.obolibrary.org/obo/GO_0070873 regulation of glycogen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. http://purl.obolibrary.org/obo/GO_0005996 monosaccharide metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. http://purl.obolibrary.org/obo/GO_0006006 glucose metabolic process http://purl.obolibrary.org/obo/GO_0019318 hexose metabolic process The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. http://purl.obolibrary.org/obo/GO_0006007 glucose catabolic process http://purl.obolibrary.org/obo/GO_0019320 hexose catabolic process The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006023 aminoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006024 glycosaminoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0006026 aminoglycan catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006027 glycosaminoglycan catabolic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0006083 acetate metabolic process http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving acetate, the anion of acetic acid. http://purl.obolibrary.org/obo/GO_0006091 generation of precursor metabolites and energy http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. http://purl.obolibrary.org/obo/GO_0006094 gluconeogenesis http://purl.obolibrary.org/obo/GO_0019319 hexose biosynthetic process The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. http://purl.obolibrary.org/obo/GO_0006109 regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. http://purl.obolibrary.org/obo/GO_0006111 regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0043255 regulation of carbohydrate biosynthetic process Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. http://purl.obolibrary.org/obo/GO_0006112 energy reserve metabolic process http://purl.obolibrary.org/obo/GO_0015980 energy derivation by oxidation of organic compounds The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. http://purl.obolibrary.org/obo/GO_0006139 nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0006403 RNA localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization A process in which RNA is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0006417 regulation of translation http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0006446 regulation of translational initiation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate, extent or accuracy of translational elongation. http://purl.obolibrary.org/obo/GO_0006449 regulation of translational termination http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0006516 glycoprotein catabolic process http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0006518 peptide metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0006586 indolalkylamine metabolic process http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. http://purl.obolibrary.org/obo/GO_0006643 membrane lipid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane. http://purl.obolibrary.org/obo/GO_0006694 steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. http://purl.obolibrary.org/obo/GO_0006699 bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/GO_0006706 steroid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein. http://purl.obolibrary.org/obo/GO_0006811 monoatomic ion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0006812 monoatomic cation transport http://purl.obolibrary.org/obo/GO_0006811 monoatomic ion transport The directed movement of a monoatomic cation, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0006835 dicarboxylic acid transport http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006846 acetate transport http://purl.obolibrary.org/obo/GO_0015718 monocarboxylic acid transport The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006847 plasma membrane acetate transport http://purl.obolibrary.org/obo/GO_0035433 acetate transmembrane transport The directed movement of acetate across a plasma membrane. http://purl.obolibrary.org/obo/GO_0006858 extracellular transport http://purl.obolibrary.org/obo/GO_0006810 transport The transport of substances that occurs outside cells. http://purl.obolibrary.org/obo/GO_0006860 extracellular amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed extracellular movement of amino acids. http://purl.obolibrary.org/obo/GO_0006873 intracellular monoatomic ion homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of monoatomic ions within a cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0006883 intracellular sodium ion homeostasis http://purl.obolibrary.org/obo/GO_0055078 sodium ion homeostasis A homeostatic process involved in the maintenance of a steady state level of sodium ions within a cell. http://purl.obolibrary.org/obo/GO_0006887 exocytosis http://purl.obolibrary.org/obo/GO_0032940 secretion by cell A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. http://purl.obolibrary.org/obo/GO_0006892 post-Golgi vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0048193 Golgi vesicle transport The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. http://purl.obolibrary.org/obo/GO_0006893 Golgi to plasma membrane transport http://purl.obolibrary.org/obo/GO_0098876 vesicle-mediated transport to the plasma membrane The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. http://purl.obolibrary.org/obo/GO_0006896 Golgi to vacuole transport http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport The directed movement of substances from the Golgi to the vacuole. http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. http://purl.obolibrary.org/obo/GO_0006906 vesicle fusion http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion Fusion of the membrane of a transport vesicle with its target membrane. http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. http://purl.obolibrary.org/obo/GO_0006936 muscle contraction http://purl.obolibrary.org/obo/GO_0003012 muscle system process A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process Any process that modulates the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006936 muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. http://purl.obolibrary.org/obo/GO_0006942 regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction Any process that modulates the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0006996 organelle organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0006998 nuclear envelope organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. http://purl.obolibrary.org/obo/GO_0007000 nucleolus organization http://purl.obolibrary.org/obo/GO_0006997 nucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus. http://purl.obolibrary.org/obo/GO_0007015 actin filament organization http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. http://purl.obolibrary.org/obo/GO_0007019 microtubule depolymerization http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization The removal of tubulin heterodimers from one or both ends of a microtubule. http://purl.obolibrary.org/obo/GO_0007020 microtubule nucleation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). http://purl.obolibrary.org/obo/GO_0007026 negative regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1902904 negative regulation of supramolecular fiber organization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. http://purl.obolibrary.org/obo/GO_0007027 negative regulation of axonemal microtubule depolymerization http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme. http://purl.obolibrary.org/obo/GO_0007028 cytoplasm organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0007030 Golgi organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances into, out of or within a vacuole. http://purl.obolibrary.org/obo/GO_0007039 protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation http://purl.obolibrary.org/obo/GO_0022402 cell cycle process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_0007076 mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0007077 mitotic nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis. http://purl.obolibrary.org/obo/GO_0007088 regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division Any process that modulates the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0007113 endomitotic cell cycle http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell. http://purl.obolibrary.org/obo/GO_0007143 female meiotic nuclear division http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0007276 gamete generation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. http://purl.obolibrary.org/obo/GO_0007281 germ cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. http://purl.obolibrary.org/obo/GO_0007292 female gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. http://purl.obolibrary.org/obo/GO_0007293 germarium-derived egg chamber formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007308 oocyte construction http://purl.obolibrary.org/obo/GO_0048469 cell maturation The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007346 regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates the rate or extent of progress through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0007399 nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0007406 negative regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_1902692 regulation of neuroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. http://purl.obolibrary.org/obo/GO_0007416 synapse assembly http://purl.obolibrary.org/obo/GO_0050808 synapse organization The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). http://purl.obolibrary.org/obo/GO_0007417 central nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0007420 brain development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). http://purl.obolibrary.org/obo/GO_0007422 peripheral nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/GO_0007439 ectodermal digestive tract development http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm. http://purl.obolibrary.org/obo/GO_0007440 foregut morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the foregut are generated and organized. http://purl.obolibrary.org/obo/GO_0007442 hindgut morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the hindgut are generated and organized. http://purl.obolibrary.org/obo/GO_0007494 midgut development http://purl.obolibrary.org/obo/GO_0048565 digestive tract development The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. http://purl.obolibrary.org/obo/GO_0007498 mesoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. http://purl.obolibrary.org/obo/GO_0007506 gonadal mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. http://purl.obolibrary.org/obo/GO_0007517 muscle organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. http://purl.obolibrary.org/obo/GO_0007528 neuromuscular junction development http://purl.obolibrary.org/obo/GO_0050808 synapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. http://purl.obolibrary.org/obo/GO_0007548 sex differentiation http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The establishment of the sex of an organism by physical differentiation. http://purl.obolibrary.org/obo/GO_0007586 digestion http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0007588 excretion http://purl.obolibrary.org/obo/GO_0003008 system process The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. http://purl.obolibrary.org/obo/GO_0007589 body fluid secretion http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels The controlled release of a fluid by a cell or tissue in an animal. http://purl.obolibrary.org/obo/GO_0007600 sensory perception http://purl.obolibrary.org/obo/GO_0050877 nervous system process The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0007601 visual perception http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. http://purl.obolibrary.org/obo/GO_0007605 sensory perception of sound http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0007626 locomotory behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. http://purl.obolibrary.org/obo/GO_0008015 blood circulation http://purl.obolibrary.org/obo/GO_0003013 circulatory system process The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. http://purl.obolibrary.org/obo/GO_0008028 monocarboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group. http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule The directed movement of organelles or molecules along microtubules in neuron projections. http://purl.obolibrary.org/obo/GO_0008104 protein localization http://purl.obolibrary.org/obo/GO_0070727 cellular macromolecule localization Any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0008152 metabolic process http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation. http://purl.obolibrary.org/obo/GO_0008202 steroid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0008291 acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_1900619 acetate ester metabolic process The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. http://purl.obolibrary.org/obo/GO_0008406 gonad development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. http://purl.obolibrary.org/obo/GO_0008504 monoamine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0008643 carbohydrate transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0009100 glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0009112 nucleobase metabolic process http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. http://purl.obolibrary.org/obo/GO_0009250 glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0000271 polysaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0009251 glucan catabolic process http://purl.obolibrary.org/obo/GO_0000272 polysaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus http://purl.obolibrary.org/obo/GO_0009314 response to radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. http://purl.obolibrary.org/obo/GO_0009566 fertilization http://purl.obolibrary.org/obo/GO_0022414 reproductive process The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009584 detection of visible light http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. http://purl.obolibrary.org/obo/GO_0009712 catechol-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0018958 phenol-containing compound metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. http://purl.obolibrary.org/obo/GO_0009820 alkaloid metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). http://purl.obolibrary.org/obo/GO_0010160 formation of animal organ boundary http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. http://purl.obolibrary.org/obo/GO_0010256 endomembrane system organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010565 regulation of ketone metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0010566 regulation of ketone biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0010608 post-transcriptional regulation of gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. http://purl.obolibrary.org/obo/GO_0010629 negative regulation of gene expression http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010876 lipid localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a lipid is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0010906 regulation of glucose metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. http://purl.obolibrary.org/obo/GO_0010962 regulation of glucan biosynthetic process http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. http://purl.obolibrary.org/obo/GO_0012505 endomembrane system http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. http://purl.obolibrary.org/obo/GO_0014902 myotube differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0015031 protein transport http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015075 monoatomic ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015081 sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity Enables the transfer of sodium ions (Na+) from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015116 sulfate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901682 sulfur compound transmembrane transporter activity Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015149 hexose transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015145 monosaccharide transmembrane transporter activity Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015205 nucleobase transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015671 oxygen transport http://purl.obolibrary.org/obo/GO_0015669 gas transport The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015718 monocarboxylic acid transport http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015837 amine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015844 monoamine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. http://purl.obolibrary.org/obo/GO_0015851 nucleobase transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015931 nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015932 nucleobase-containing compound transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015980 energy derivation by oxidation of organic compounds http://purl.obolibrary.org/obo/GO_0006091 generation of precursor metabolites and energy The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released. http://purl.obolibrary.org/obo/GO_0016020 membrane http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0016043 cellular component organization http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. http://purl.obolibrary.org/obo/GO_0016325 oocyte microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0030951 establishment or maintenance of microtubule cytoskeleton polarity Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0018958 phenol-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific behavior of an organism that is associated with reproduction. http://purl.obolibrary.org/obo/GO_0019218 regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0019219 regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0019318 hexose metabolic process http://purl.obolibrary.org/obo/GO_0005996 monosaccharide metabolic process The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0019319 hexose biosynthetic process http://purl.obolibrary.org/obo/GO_0046364 monosaccharide biosynthetic process The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0019320 hexose catabolic process http://purl.obolibrary.org/obo/GO_0046365 monosaccharide catabolic process The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving a protein. Includes protein modification. http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the cell. http://purl.obolibrary.org/obo/GO_0019748 secondary metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0021700 developmental maturation http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A cellular process that results in the breakdown of a cellular component. http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of a gland are generated and organized. http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0030003 intracellular monoatomic cation homeostasis http://purl.obolibrary.org/obo/GO_0055080 monoatomic cation homeostasis A homeostatic process involved in the maintenance of a steady state level of monoatomic cations within a cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0030017 sarcomere http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly http://purl.obolibrary.org/obo/GO_0030030 cell projection organization Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0030054 cell junction http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0030262 apoptotic nuclear changes http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. http://purl.obolibrary.org/obo/GO_0030936 transmembrane collagen trimer http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex Any collagen trimer that passes through a lipid bilayer membrane. http://purl.obolibrary.org/obo/GO_0030990 intraciliary transport particle http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. http://purl.obolibrary.org/obo/GO_0031109 microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. http://purl.obolibrary.org/obo/GO_0031111 negative regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1901879 regulation of protein depolymerization Any process that modulates the frequency, rate or extent of microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0031345 negative regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031965 nuclear membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. http://purl.obolibrary.org/obo/GO_0031967 organelle envelope http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane http://purl.obolibrary.org/obo/GO_0019867 outer membrane The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope. http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. http://purl.obolibrary.org/obo/GO_0032365 intracellular lipid transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032368 regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). http://purl.obolibrary.org/obo/GO_0033013 tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. http://purl.obolibrary.org/obo/GO_0033014 tetrapyrrole biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. http://purl.obolibrary.org/obo/GO_0033015 tetrapyrrole catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a macromolecule is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033037 polysaccharide localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a polysaccharide is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0033238 regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. http://purl.obolibrary.org/obo/GO_0034329 cell junction assembly http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein transports or maintains the localization of another protein to the nucleus. http://purl.obolibrary.org/obo/GO_0034655 nucleobase-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0034765 regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035082 axoneme assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_0035265 organ growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. http://purl.obolibrary.org/obo/GO_0035272 exocrine system development http://purl.obolibrary.org/obo/GO_0048731 system development Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. http://purl.obolibrary.org/obo/GO_0035295 tube development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. http://purl.obolibrary.org/obo/GO_0035433 acetate transmembrane transport http://purl.obolibrary.org/obo/GO_1905039 carboxylic acid transmembrane transport The process in which acetate is transported across a membrane. Acetate is the 2-carbon carboxylic acid ethanoic acid. http://purl.obolibrary.org/obo/GO_0035725 sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0042175 nuclear outer membrane-endoplasmic reticulum membrane network http://purl.obolibrary.org/obo/GO_0016020 membrane The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. http://purl.obolibrary.org/obo/GO_0042180 ketone metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0042181 ketone biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0042182 ketone catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0042427 serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042430 indole-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042461 photoreceptor cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. http://purl.obolibrary.org/obo/GO_0042886 amide transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0042887 amide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0043005 neuron projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. http://purl.obolibrary.org/obo/GO_0043066 negative regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043255 regulation of carbohydrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. http://purl.obolibrary.org/obo/GO_0043455 regulation of secondary metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. http://purl.obolibrary.org/obo/GO_0043470 regulation of carbohydrate catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. http://purl.obolibrary.org/obo/GO_0043648 dicarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0043649 dicarboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0043650 dicarboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0044042 glucan metabolic process http://purl.obolibrary.org/obo/GO_0005976 polysaccharide metabolic process The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. http://purl.obolibrary.org/obo/GO_0044060 regulation of endocrine process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044550 secondary metabolite biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0045214 sarcomere organization http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organization The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0045596 negative regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045930 negative regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0046113 nucleobase catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0046365 monosaccharide catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. http://purl.obolibrary.org/obo/GO_0046785 microtubule polymerization http://purl.obolibrary.org/obo/GO_0051258 protein polymerization The addition of tubulin heterodimers to one or both ends of a microtubule. http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0046907 intracellular transport http://purl.obolibrary.org/obo/GO_0051641 cellular localization The directed movement of substances within a cell. http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport http://purl.obolibrary.org/obo/GO_0015849 organic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008514 organic anion transmembrane transporter activity Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0048066 developmental pigmentation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. http://purl.obolibrary.org/obo/GO_0048193 Golgi vesicle transport http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. http://purl.obolibrary.org/obo/GO_0048477 oogenesis http://purl.obolibrary.org/obo/GO_0007292 female gamete generation The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0048523 negative regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0048546 digestive tract morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. http://purl.obolibrary.org/obo/GO_0048565 digestive tract development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed. http://purl.obolibrary.org/obo/GO_0048580 regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. http://purl.obolibrary.org/obo/GO_0048753 pigment granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. http://purl.obolibrary.org/obo/GO_0048806 genitalia development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048812 neuron projection morphogenesis http://purl.obolibrary.org/obo/GO_0120039 plasma membrane bounded cell projection morphogenesis The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0050658 RNA transport http://purl.obolibrary.org/obo/GO_0051236 establishment of RNA localization The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0050768 negative regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0050801 monoatomic ion homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of monoatomic ions within an organism or cell. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0050890 cognition http://purl.obolibrary.org/obo/GO_0050877 nervous system process The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. http://purl.obolibrary.org/obo/GO_0050896 response to stimulus http://purl.obolibrary.org/obo/GO_0008150 biological process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0051081 nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly The controlled breakdown of the nuclear membranes, for example during cellular division. http://purl.obolibrary.org/obo/GO_0051119 sugar transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015144 carbohydrate transmembrane transporter activity Enables the transfer of a sugar from one side of a membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides. http://purl.obolibrary.org/obo/GO_0051169 nuclear transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances into, out of, or within the nucleus. http://purl.obolibrary.org/obo/GO_0051234 establishment of localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0051261 protein depolymerization http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. http://purl.obolibrary.org/obo/GO_0051649 establishment of localization in cell http://purl.obolibrary.org/obo/GO_0051234 establishment of localization Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of a vesicle to a specific location. http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0055078 sodium ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. http://purl.obolibrary.org/obo/GO_0060047 heart contraction http://purl.obolibrary.org/obo/GO_0003015 heart process The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body. http://purl.obolibrary.org/obo/GO_0060281 regulation of oocyte development http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060322 head development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/GO_0060404 axonemal microtubule depolymerization http://purl.obolibrary.org/obo/GO_0061523 cilium disassembly The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules. http://purl.obolibrary.org/obo/GO_0060541 respiratory system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_0060612 adipose tissue development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat. http://purl.obolibrary.org/obo/GO_0061024 membrane organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. http://purl.obolibrary.org/obo/GO_0061061 muscle structure development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. http://purl.obolibrary.org/obo/GO_0061525 hindgut development http://purl.obolibrary.org/obo/GO_0048565 digestive tract development The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut. http://purl.obolibrary.org/obo/GO_0065002 intracellular protein transmembrane transport http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen http://purl.obolibrary.org/obo/GO_0043233 organelle lumen An organelle lumen that is part of an intracellular organelle. http://purl.obolibrary.org/obo/GO_0070161 anchoring junction http://purl.obolibrary.org/obo/GO_0030054 cell junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. http://purl.obolibrary.org/obo/GO_0070192 chromosome organization involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process of chromosome organization that is involved in a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0070382 exocytic vesicle http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. http://purl.obolibrary.org/obo/GO_0070873 regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0071377 cellular response to glucagon stimulus http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0071944 cell periphery http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. http://purl.obolibrary.org/obo/GO_0072089 stem cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0072329 monocarboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. http://purl.obolibrary.org/obo/GO_0072359 circulatory system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0072666 establishment of protein localization to vacuole http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole The directed movement of a protein to a specific location in a vacuole. http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localization to membrane http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process Any cellular metabolic process involving nucleic acids. http://purl.obolibrary.org/obo/GO_0097014 ciliary plasm http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. http://purl.obolibrary.org/obo/GO_0097194 execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0009987 cellular process A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer http://purl.obolibrary.org/obo/GO_0005581 collagen trimer A collagen trimer that forms networks. http://purl.obolibrary.org/obo/GO_0098643 banded collagen fibril http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands). http://purl.obolibrary.org/obo/GO_0098645 collagen network http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer A supramolecular complex that consists of collagen triple helices associated to form a network. http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of a synapse that is part of the presynaptic cell. http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A cell projection supported by an assembly of actin filaments, and which lacks microtubules. http://purl.obolibrary.org/obo/GO_0098876 vesicle-mediated transport to the plasma membrane http://purl.obolibrary.org/obo/GO_0051668 localization within membrane The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from pre to post-synapse, across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. http://purl.obolibrary.org/obo/GO_0099500 vesicle fusion to plasma membrane http://purl.obolibrary.org/obo/GO_0140029 exocytic process Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0099531 presynaptic process involved in chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050877 nervous system process The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission. http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. http://purl.obolibrary.org/obo/GO_0099643 signal release from synapse http://purl.obolibrary.org/obo/GO_0023061 signal release Any signal release from a synapse. http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901160 primary amino compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving primary amino compound. http://purl.obolibrary.org/obo/GO_1901375 acetate ester transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an acetate ester from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901505 carbohydrate derivative transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carbohydrate derivative from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901606 alpha-amino acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901880 negative regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1902850 microtubule cytoskeleton organization involved in mitosis http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process Any microtubule cytoskeleton organization that is involved in mitosis. http://purl.obolibrary.org/obo/GO_1902903 regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of supramolecular fiber organization. http://purl.obolibrary.org/obo/GO_1902904 negative regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization. http://purl.obolibrary.org/obo/GO_1903429 regulation of cell maturation http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1903825 organic acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015849 organic acid transport The process in which an organic acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_1904659 D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0008645 hexose transmembrane transport The process in which D-glucose is transported across a membrane. http://purl.obolibrary.org/obo/GO_2000178 negative regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000647 negative regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_0045818 negative regulation of glycogen catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. http://purl.obolibrary.org/obo/GO_0045819 positive regulation of glycogen catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0045843 negative regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_0048635 negative regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0045844 positive regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_0048636 positive regulation of muscle organ development Any process that activates or increases the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0045900 negative regulation of translational elongation http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. http://purl.obolibrary.org/obo/GO_0045901 positive regulation of translational elongation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational elongation. http://purl.obolibrary.org/obo/GO_0045904 negative regulation of translational termination http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0045905 positive regulation of translational termination http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0045914 negative regulation of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. http://purl.obolibrary.org/obo/GO_0045915 positive regulation of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. http://purl.obolibrary.org/obo/GO_0045931 positive regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that activates or increases the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0045932 negative regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0045933 positive regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0045986 negative regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0045987 positive regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0045992 negative regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0046548 retinal rod cell development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. http://purl.obolibrary.org/obo/GO_0046549 retinal cone cell development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. http://purl.obolibrary.org/obo/GO_0046666 retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Programmed cell death that occurs in the developing retina. http://purl.obolibrary.org/obo/GO_0046667 compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046666 retinal cell programmed cell death Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium. http://purl.obolibrary.org/obo/GO_0046668 regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0046669 regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046668 regulation of retinal cell programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0046670 positive regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0046671 negative regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0046672 positive regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046670 positive regulation of retinal cell programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0046673 negative regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046671 negative regulation of retinal cell programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0046676 negative regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0050796 regulation of insulin secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/GO_0046681 response to carbamate http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase. http://purl.obolibrary.org/obo/GO_0046716 muscle cell cellular homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. http://purl.obolibrary.org/obo/GO_0047496 vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. http://purl.obolibrary.org/obo/GO_0048048 embryonic eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. http://purl.obolibrary.org/obo/GO_0048070 regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0120305 regulation of pigmentation Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0048086 negative regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0048087 positive regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0048132 female germ-line stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098728 germline stem cell asymmetric division The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes. http://purl.obolibrary.org/obo/GO_0048144 fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. http://purl.obolibrary.org/obo/GO_0048145 regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048146 positive regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048147 negative regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048251 elastic fiber assembly http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. http://purl.obolibrary.org/obo/GO_0048280 vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0007030 Golgi organization The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. http://purl.obolibrary.org/obo/GO_0048288 nuclear membrane fusion involved in karyogamy http://purl.obolibrary.org/obo/GO_0000740 nuclear membrane fusion The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei. http://purl.obolibrary.org/obo/GO_0048313 Golgi inheritance http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance The partitioning of Golgi apparatus between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0048318 axial mesoderm development http://purl.obolibrary.org/obo/GO_0007498 mesoderm development The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. http://purl.obolibrary.org/obo/GO_0048319 axial mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis The process in which the anatomical structures of the axial mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048320 axial mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048339 paraxial mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. http://purl.obolibrary.org/obo/GO_0048340 paraxial mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of the paraxial mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048341 paraxial mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048369 lateral mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of the lateral mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048370 lateral mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048389 intermediate mesoderm development http://purl.obolibrary.org/obo/GO_0007498 mesoderm development The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/GO_0048390 intermediate mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis The process in which the anatomical structures of the intermediate mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048391 intermediate mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048485 sympathetic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. http://purl.obolibrary.org/obo/GO_0048536 spleen development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. http://purl.obolibrary.org/obo/GO_0048539 bone marrow development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048601 oocyte morphogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte. http://purl.obolibrary.org/obo/GO_0048627 myoblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0048630 skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. http://purl.obolibrary.org/obo/GO_0048631 regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_0048632 negative regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_0048633 positive regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_0048644 muscle organ morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0048659 smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0048660 regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0048661 positive regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0048662 negative regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0048741 skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0014904 myotube cell development The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048742 regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048743 positive regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048744 negative regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048745 smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048755 branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). http://purl.obolibrary.org/obo/GO_0048854 brain morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). http://purl.obolibrary.org/obo/GO_0048880 sensory system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048934 peripheral nervous system neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0048935 peripheral nervous system neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. http://purl.obolibrary.org/obo/GO_0050657 nucleic acid transport http://purl.obolibrary.org/obo/GO_0015931 nucleobase-containing compound transport The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0050708 regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050709 negative regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050803 regulation of synapse structure or activity http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. http://purl.obolibrary.org/obo/GO_0050908 detection of light stimulus involved in visual perception http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050952 sensory perception of electrical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0050956 electroception http://purl.obolibrary.org/obo/GO_0050952 sensory perception of electrical stimulus The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location. http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. http://purl.obolibrary.org/obo/GO_0050963 detection of electrical stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0050981 detection of electrical stimulus The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception. http://purl.obolibrary.org/obo/GO_0050964 detection of electrical stimulus involved in electroception http://purl.obolibrary.org/obo/GO_0050963 detection of electrical stimulus involved in sensory perception The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050967 detection of electrical stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0062149 detection of stimulus involved in sensory perception of pain The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050968 detection of chemical stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0062149 detection of stimulus involved in sensory perception of pain The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050975 sensory perception of touch http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach). http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information. http://purl.obolibrary.org/obo/GO_0051033 RNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051078 meiotic nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs. http://purl.obolibrary.org/obo/GO_0051150 regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051151 negative regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051148 negative regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051152 positive regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051149 positive regulation of muscle cell differentiation Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051236 establishment of RNA localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of RNA to a specific location. http://purl.obolibrary.org/obo/GO_0051303 establishment of chromosome localization http://purl.obolibrary.org/obo/GO_0050000 chromosome localization The directed movement of a chromosome to a specific location. http://purl.obolibrary.org/obo/GO_0051410 detoxification of nitrogen compound http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances. http://purl.obolibrary.org/obo/GO_0051588 regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051589 negative regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051620 norepinephrine uptake http://purl.obolibrary.org/obo/GO_0015874 norepinephrine transport The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0051621 regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_0051622 negative regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_0051623 positive regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_0051630 acetylcholine uptake http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0051631 regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_0051632 negative regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_0051633 positive regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_0051641 cellular localization http://purl.obolibrary.org/obo/GO_0051179 localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. http://purl.obolibrary.org/obo/GO_0051645 Golgi localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051683 establishment of Golgi localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the Golgi to a specific location. http://purl.obolibrary.org/obo/GO_0051784 negative regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0051785 positive regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0051891 positive regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0051964 negative regulation of synapse assembly http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_0051965 positive regulation of synapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_0051984 positive regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060282 positive regulation of oocyte development http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060283 negative regulation of oocyte development http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060456 positive regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of a branched epithelium are generated and organized. http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061572 actin filament bundle organization http://purl.obolibrary.org/obo/GO_0007015 actin filament organization A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. http://purl.obolibrary.org/obo/GO_0065007 biological regulation http://purl.obolibrary.org/obo/GO_0008150 biological process Any process that modulates a measurable attribute of any biological process, quality or function. http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0090278 negative regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0090493 catecholamine uptake http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of catecholamine into a cell. http://purl.obolibrary.org/obo/GO_0098728 germline stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes. http://purl.obolibrary.org/obo/GO_0099569 presynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the presynapse. http://purl.obolibrary.org/obo/GO_1900076 regulation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus. http://purl.obolibrary.org/obo/GO_1900077 negative regulation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus. http://purl.obolibrary.org/obo/GO_1900078 positive regulation of cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus. http://purl.obolibrary.org/obo/GO_1900377 negative regulation of secondary metabolite biosynthetic process http://purl.obolibrary.org/obo/GO_1900376 regulation of secondary metabolite biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process. http://purl.obolibrary.org/obo/GO_1901694 positive regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901862 negative regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1901863 positive regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that activates or increases the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1901889 negative regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1901890 positive regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1902680 positive regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1903523 negative regulation of blood circulation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1903524 positive regulation of blood circulation http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1904397 negative regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904398 positive regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_1904396 regulation of neuromuscular junction development Any process that activates or increases the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904888 cranial skeletal system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. http://purl.obolibrary.org/obo/GO_1904950 negative regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1904951 positive regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1905207 regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1905208 negative regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1905209 positive regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1905772 positive regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1990009 retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a retinal cell. http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000737 negative regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000738 positive regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000832 negative regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000833 positive regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_1903697 negative regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly. http://purl.obolibrary.org/obo/GO_1903698 positive regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of microvillus assembly. http://purl.obolibrary.org/obo/GO_1903701 substantia propria of cornea development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903702 esophagus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903789 regulation of amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of amino acid transmembrane transport. http://purl.obolibrary.org/obo/GO_1903847 regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905651 regulation of artery morphogenesis Any process that modulates the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903848 negative regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905652 negative regulation of artery morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903849 positive regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905653 positive regulation of artery morphogenesis Any process that activates or increases the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903941 negative regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_1903942 positive regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_1903943 regulation of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1903944 negative regulation of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1903945 positive regulation of hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1903950 negative regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential. http://purl.obolibrary.org/obo/GO_1903951 positive regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential Any process that activates or increases the frequency, rate or extent of AV node cell action potential. http://purl.obolibrary.org/obo/GO_1904014 response to serotonin http://purl.obolibrary.org/obo/GO_0071867 response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. http://purl.obolibrary.org/obo/GO_1904015 cellular response to serotonin http://purl.obolibrary.org/obo/GO_0071868 cellular response to monoamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. http://purl.obolibrary.org/obo/GO_1904026 regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1904027 negative regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1904028 positive regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization Any process that activates or increases the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1904054 regulation of cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of cholangiocyte proliferation. http://purl.obolibrary.org/obo/GO_1904055 negative regulation of cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation. http://purl.obolibrary.org/obo/GO_1904056 positive regulation of cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation. http://purl.obolibrary.org/obo/GO_1904057 negative regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1904058 positive regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that activates or increases the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1904073 regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1904074 negative regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1904075 positive regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1904106 protein localization to microvillus http://purl.obolibrary.org/obo/GO_0008104 protein localization A process in which a protein is transported to, or maintained in, a location within a microvillus. http://purl.obolibrary.org/obo/GO_1904145 negative regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1904146 positive regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1904170 regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904171 negative regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904172 positive regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904177 regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1904178 negative regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1904179 positive regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1904192 regulation of cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1904193 negative regulation of cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1904194 positive regulation of cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1904204 regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1904205 negative regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1904206 positive regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1904269 cell leading edge cell cortex http://purl.obolibrary.org/obo/GO_0099738 cell cortex region The cell cortex of the leading edge of a cell. http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904305 negative regulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904306 positive regulation of gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904341 regulation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that modulates the frequency, rate or extent of colon smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904342 negative regulation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904341 regulation of colon smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904343 positive regulation of colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904341 regulation of colon smooth muscle contraction Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904344 regulation of gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation. http://purl.obolibrary.org/obo/GO_1904345 negative regulation of gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_1904344 regulation of gastric mucosal blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation. http://purl.obolibrary.org/obo/GO_1904346 positive regulation of gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_1904344 regulation of gastric mucosal blood circulation Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation. http://purl.obolibrary.org/obo/GO_1904347 regulation of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904304 regulation of gastro-intestinal system smooth muscle contraction Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904348 negative regulation of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904347 regulation of small intestine smooth muscle contraction Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904349 positive regulation of small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_1904347 regulation of small intestine smooth muscle contraction Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction. http://purl.obolibrary.org/obo/GO_1904350 regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0042176 regulation of protein catabolic process Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1904351 negative regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0042177 negative regulation of protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1904352 positive regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0045732 positive regulation of protein catabolic process Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1904409 regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904410 negative regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904411 positive regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904412 regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1904413 negative regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1904414 positive regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1904456 negative regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0051970 negative regulation of transmission of nerve impulse Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential. http://purl.obolibrary.org/obo/GO_1904457 positive regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0051971 positive regulation of transmission of nerve impulse Any process that activates or increases the frequency, rate or extent of neuronal action potential. http://purl.obolibrary.org/obo/GO_1904484 cloacal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904588 cellular response to glycoprotein http://purl.obolibrary.org/obo/GO_1904587 response to glycoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. http://purl.obolibrary.org/obo/GO_1904606 fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a fat cell. http://purl.obolibrary.org/obo/GO_1904649 regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904650 negative regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_1904649 regulation of fat cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904651 positive regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904675 regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division Any process that modulates the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904676 negative regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904677 positive regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division Any process that activates or increases the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904691 negative regulation of type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0061469 regulation of type B pancreatic cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation. http://purl.obolibrary.org/obo/GO_1904692 positive regulation of type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0061469 regulation of type B pancreatic cell proliferation Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation. http://purl.obolibrary.org/obo/GO_1904693 midbrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process by which a midbrain is generated and organized. http://purl.obolibrary.org/obo/GO_1904697 regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1904698 negative regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1904699 positive regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0048660 regulation of smooth muscle cell proliferation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1904706 negative regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1904707 positive regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1904749 regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus Any process that modulates the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_1904750 negative regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_1904751 positive regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_1904770 intramembranous bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The developmental process by which an intramembranous bone is generated and organized. http://purl.obolibrary.org/obo/GO_1904776 regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_1904777 negative regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_1904778 positive regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_1904817 serous membrane development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904818 visceral peritoneum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904819 parietal peritoneum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904820 peritoneum development http://purl.obolibrary.org/obo/GO_1904817 serous membrane development The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904829 regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904830 negative regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905064 negative regulation of vascular associated smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904831 positive regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905065 positive regulation of vascular associated smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904933 regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_1904934 negative regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_1904933 regulation of cell proliferation in midbrain Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_1904935 positive regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_1904942 regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation Any process that modulates the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_1904943 negative regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901211 negative regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_1904944 positive regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901212 positive regulation of cardiac chamber formation Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051150 regulation of smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1905064 negative regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1905065 positive regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1905126 regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport Any process that modulates the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_1905127 negative regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_1905128 positive regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_1905139 apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_1905140 regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_1905141 negative regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_1905142 positive regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_1905144 response to acetylcholine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. http://purl.obolibrary.org/obo/GO_1905147 regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1905148 negative regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1905149 positive regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1905213 negative regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1905223 epicardium morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process by which an epicardium is generated and organized. http://purl.obolibrary.org/obo/GO_1905277 negative regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905288 vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell apoptotic process Any apoptotic process in a vascular associated smooth muscle cell. http://purl.obolibrary.org/obo/GO_1905298 regulation of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of intestinal epithelial cell development. http://purl.obolibrary.org/obo/GO_1905299 negative regulation of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development. http://purl.obolibrary.org/obo/GO_1905300 positive regulation of intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development. http://purl.obolibrary.org/obo/GO_1905304 regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905305 negative regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905306 positive regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905315 cell proliferation involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis Any cell proliferation that is involved in endocardial cushion morphogenesis. http://purl.obolibrary.org/obo/GO_1905384 regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse Any process that modulates the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_1905385 negative regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_1905386 positive regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1902474 positive regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_1905432 regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_1905433 negative regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_1905434 positive regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_1905453 regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905454 negative regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905455 positive regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905459 regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptotic process Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905460 negative regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034392 negative regulation of smooth muscle cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905461 positive regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034393 positive regulation of smooth muscle cell apoptotic process Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905492 positive regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_1905553 regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_1905554 negative regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_1905555 positive regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis Any process that activates or increases the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_1905557 regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0010549 regulation of membrane disassembly Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_1905558 negative regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_1905559 positive regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_1905562 regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001936 regulation of endothelial cell proliferation Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1905563 negative regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001937 negative regulation of endothelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1905564 positive regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001938 positive regulation of endothelial cell proliferation Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1905606 regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that modulates the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_1905607 negative regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_1905606 regulation of presynapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_1905608 positive regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_1905627 regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_1905628 negative regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_1905629 positive regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_1905651 regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_1905652 negative regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_1905653 positive regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_1990705 cholangiocyte proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. http://purl.obolibrary.org/obo/GO_1990765 colon smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum. http://purl.obolibrary.org/obo/GO_1990768 gastric mucosal blood circulation http://purl.obolibrary.org/obo/GO_0008015 blood circulation The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products. http://purl.obolibrary.org/obo/GO_1990770 small intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine. http://purl.obolibrary.org/obo/GO_1990863 acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus). http://purl.obolibrary.org/obo/GO_1990874 vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0048659 smooth muscle cell proliferation The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of stem cell division. http://purl.obolibrary.org/obo/GO_2000172 regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/UBERON_0000000 processual entity http://purl.obolibrary.org/obo/BFO_0000003 occurrent An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. http://purl.obolibrary.org/obo/UBERON_0000006 islet of Langerhans http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster The clusters of hormone-producing cells that are scattered throughout the pancreas. http://purl.obolibrary.org/obo/UBERON_0000009 submucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0000013 sympathetic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]. http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. http://purl.obolibrary.org/obo/UBERON_0000018 compound eye http://purl.obolibrary.org/obo/UBERON_0015165 multi-unit eye A light sensing organ composed of ommatidia. http://purl.obolibrary.org/obo/UBERON_0000019 camera-type eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid. http://purl.obolibrary.org/obo/UBERON_0000025 tube http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. http://purl.obolibrary.org/obo/UBERON_0000026 appendage http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Major subdivision of an organism that protrudes from the body[DOS, CARO]. http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions. http://purl.obolibrary.org/obo/UBERON_0000031 lamina propria of trachea http://purl.obolibrary.org/obo/UBERON_0004779 respiratory system lamina propria A lamina propria that is part of a respiratory airway. http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. http://purl.obolibrary.org/obo/UBERON_0000043 tendon http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue Dense regular connective tissue that connects muscle to bone[VSAO]. http://purl.obolibrary.org/obo/UBERON_0000045 ganglion http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A biological tissue mass, most commonly a mass of nerve cell bodies. http://purl.obolibrary.org/obo/UBERON_0000047 simple eye http://purl.obolibrary.org/obo/UBERON_0000970 eye An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity. http://purl.obolibrary.org/obo/UBERON_0000055 vessel http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular structure that contains, conveys body fluid, such as blood or lymph. http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A tubular structure that transports secreted or excreted substances. http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. http://purl.obolibrary.org/obo/UBERON_0000062 organ http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that performs a specific function or group of functions [WP]. http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity. http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A multicellular structure that is a part of an organ. http://purl.obolibrary.org/obo/UBERON_0000066 fully formed stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A life cycle stage that starts with fertilization and ends with the fully formed embryo. http://purl.obolibrary.org/obo/UBERON_0000069 larval stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A distinct juvenile stage many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. http://purl.obolibrary.org/obo/UBERON_0000071 death stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage End of the life of an organism. http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube An section of a respiratory tract. http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. http://purl.obolibrary.org/obo/UBERON_0000076 external ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. http://purl.obolibrary.org/obo/UBERON_0000077 mixed endoderm/mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure An anatomical structure that develops from the endoderm and the mesoderm. http://purl.obolibrary.org/obo/UBERON_0000078 mixed ectoderm/mesoderm/endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure An anatomical structure that develops from the ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/UBERON_0000085 morula http://purl.obolibrary.org/obo/UBERON_0000922 embryo A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/UBERON_0000086 zona pellucida http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes. http://purl.obolibrary.org/obo/UBERON_0000087 inner cell mass http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A mass of cells that develop into the body of the embryo and some extraembryonic tissues. http://purl.obolibrary.org/obo/UBERON_0000088 trophoblast http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta. http://purl.obolibrary.org/obo/UBERON_0000091 bilaminar disc http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. http://purl.obolibrary.org/obo/UBERON_0000092 post-embryonic stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage Stage succeeding embryo, including mature structure. http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. http://purl.obolibrary.org/obo/UBERON_0000095 cardiac neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0000101 lobe of lung http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe A lung lobe is one of the rounded projections that compose the lung[GO]. http://purl.obolibrary.org/obo/UBERON_0000102 lung vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]. http://purl.obolibrary.org/obo/UBERON_0000104 life cycle http://purl.obolibrary.org/obo/UBERON_0000000 processual entity An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism. http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage http://purl.obolibrary.org/obo/UBERON_0000000 processual entity A spatiotemporal region encompassing some part of the life cycle of an organism. http://purl.obolibrary.org/obo/UBERON_0000106 zygote stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage at which the organism is a single cell produced by means of sexual reproduction. http://purl.obolibrary.org/obo/UBERON_0000107 cleavage stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. http://purl.obolibrary.org/obo/UBERON_0000108 blastula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000109 gastrula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/UBERON_0000110 neurula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A chordate developmental stage defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/UBERON_0000111 organogenesis stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. http://purl.obolibrary.org/obo/UBERON_0000114 lung connective tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin. http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium The epithelial layer of the lung. http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube in the respiratory system. Examples: bronchus, bronchiole, trachea. http://purl.obolibrary.org/obo/UBERON_0000118 lung bud http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud Structure derived from foregut that becomes a lung[GO]. http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO). http://purl.obolibrary.org/obo/UBERON_0000126 cranial nerve nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves. http://purl.obolibrary.org/obo/UBERON_0000161 orifice http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0000162 cloaca http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures. http://purl.obolibrary.org/obo/UBERON_0000163 embryonic cloaca http://purl.obolibrary.org/obo/UBERON_0000162 cloaca Endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]. http://purl.obolibrary.org/obo/UBERON_0000166 oral opening http://purl.obolibrary.org/obo/UBERON_0000161 orifice The orifice that connects the mouth to the exterior of the body. http://purl.obolibrary.org/obo/UBERON_0000168 proximal-distal subdivision of colon http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A section dividing a colon along a proximal-distal axis. http://purl.obolibrary.org/obo/UBERON_0000170 pair of lungs http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection The pair of anatomical structures comprised of a left lung and right lung. http://purl.obolibrary.org/obo/UBERON_0000171 respiration organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/UBERON_0000174 excreta http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. http://purl.obolibrary.org/obo/UBERON_0000209 tetrapod frontal bone http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone The bone forming the forehead and roof of the eye orbit. http://purl.obolibrary.org/obo/UBERON_0000220 atlanto-occipital joint http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The Atlanto-occipital joint (articulation between the atlas and the occipital bone) consists of a pair of condyloid joints. The atlanto-occipital joint is a synovial joint. The ligaments connecting the bones are: Two Articular capsules; Posterior atlantoöccipital membrane; Anterior atlantoöccipital membrane; Lateral atlantoöccipital. http://purl.obolibrary.org/obo/UBERON_0000307 blastula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine Mucosa that is part of a colon. The mucosa of the colon is lined by a simple columnar epithelium with a thin brush border and numerous goblet cells. http://purl.obolibrary.org/obo/UBERON_0000320 duodenal mucosa http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine A mucosa that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000325 gastric gland http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. http://purl.obolibrary.org/obo/UBERON_0000326 pancreatic juice http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach. http://purl.obolibrary.org/obo/UBERON_0000328 gut wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity). http://purl.obolibrary.org/obo/UBERON_0000332 yellow bone marrow http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow Bone marrow in which the fat cells predominate in the meshes of the reticular network. http://purl.obolibrary.org/obo/UBERON_0000333 intestinal gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]. http://purl.obolibrary.org/obo/UBERON_0000344 mucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]. http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma http://purl.obolibrary.org/obo/UBERON_0000064 organ part Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. http://purl.obolibrary.org/obo/UBERON_0000355 pharyngeal mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000358 blastocyst http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]. http://purl.obolibrary.org/obo/UBERON_0000361 red bone marrow http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream. http://purl.obolibrary.org/obo/UBERON_0000371 syncytiotrophoblast http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated). http://purl.obolibrary.org/obo/UBERON_0000377 maxillary nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses. http://purl.obolibrary.org/obo/UBERON_0000379 tracheal mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a respiratory airway. http://purl.obolibrary.org/obo/UBERON_0000383 musculature of body http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. http://purl.obolibrary.org/obo/UBERON_0000389 lens cortex http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Tissue that surrounds the lens nucleus. http://purl.obolibrary.org/obo/UBERON_0000390 lens nucleus http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ The core of the crystalline lens, surrounded by the cortex. http://purl.obolibrary.org/obo/UBERON_0000397 colonic epithelium http://purl.obolibrary.org/obo/UBERON_0001278 epithelium of large intestine An epithelium that is part of a colon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000409 serous gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland A gland in which the principal secretory cells are serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0000410 bronchial mucosa http://purl.obolibrary.org/obo/UBERON_0000379 tracheal mucosa A mucosa that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland A gland in which the principal secretory cells are mucus secreting cells. http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel An anatomical wall that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000440 trabecula http://purl.obolibrary.org/obo/UBERON_0000064 organ part A small, often microscopic, tissue element in the form of a small beam, strut or rod, generally having a mechanical function, and usually but not necessarily composed of dense collagenous tissue. On histological section, a trabecula can look like a septum, but in three dimensions they are topologically distinct, with trabeculae being roughly rod or pillar-shaped and septa being sheet-like. Trabeculae are usually composed of dense fibrous tissue, i.e. mainly of collagen, and in most cases provide mechanical strengthening or stiffening to a soft solid organ, such as the spleen. They can be composed of other materials, such as bone or muscle[WP]. http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is produced by exocrine glands. http://purl.obolibrary.org/obo/UBERON_0000463 organism substance http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has mass. http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has no mass. http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that is an individual member of a species and consists of more than one cell. http://purl.obolibrary.org/obo/UBERON_0000471 compound organ component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Multi-tissue structure that is part of a compound organ. http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group Anatomical group whose component anatomical structures lie in close proximity to each other. http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. http://purl.obolibrary.org/obo/UBERON_0000482 basal lamina of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue. http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. http://purl.obolibrary.org/obo/UBERON_0000484 simple cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0010077 cuboidal epithelium Unilaminar epithelium that consists of a single layer of cuboidal cells. http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000486 multilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000487 simple squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000488 atypical epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium that consists of epithelial cells not arranged in one ore more layers. http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ Compound organ that contains one or more macroscopic anatomical spaces. http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000912 mucus http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water. http://purl.obolibrary.org/obo/UBERON_0000916 abdomen http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0000922 embryo http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/UBERON_0000923 germ layer http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. http://purl.obolibrary.org/obo/UBERON_0000925 endoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. http://purl.obolibrary.org/obo/UBERON_0000926 mesoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer The middle germ layer of the embryo, between the endoderm and ectoderm. http://purl.obolibrary.org/obo/UBERON_0000930 stomodeum http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity. http://purl.obolibrary.org/obo/UBERON_0000931 proctodeum http://purl.obolibrary.org/obo/UBERON_0016566 pit Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0000957 lamina http://purl.obolibrary.org/obo/UBERON_0000479 tissue Any thin layer or plate. http://purl.obolibrary.org/obo/UBERON_0000962 nerve of cervical vertebra http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0000971 ommatidium http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells. http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint http://purl.obolibrary.org/obo/UBERON_0004905 articulation Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. http://purl.obolibrary.org/obo/UBERON_0000988 pons http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit An airway through which respiratory air passes in organisms. http://purl.obolibrary.org/obo/UBERON_0001009 circulatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Portion of connective tissue composed of adipocytes enmeshed in areolar tissue. http://purl.obolibrary.org/obo/UBERON_0001015 musculature http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A subdivision of the muscular system corresponding to a subdisivision of an organism. http://purl.obolibrary.org/obo/UBERON_0001021 nerve http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. http://purl.obolibrary.org/obo/UBERON_0001027 sensory nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that transmits from sensory receptors on the surface of the body to the central nervous system. http://purl.obolibrary.org/obo/UBERON_0001040 yolk sac http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. http://purl.obolibrary.org/obo/UBERON_0001041 foregut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Anterior subdivision of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0001042 chordate pharynx http://purl.obolibrary.org/obo/UBERON_0006562 pharynx A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. http://purl.obolibrary.org/obo/UBERON_0001045 midgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]. http://purl.obolibrary.org/obo/UBERON_0001046 hindgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The caudalmost subdivision of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. http://purl.obolibrary.org/obo/UBERON_0001049 neural tube http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/UBERON_0001064 ventral pancreatic duct http://purl.obolibrary.org/obo/UBERON_0000025 tube A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. http://purl.obolibrary.org/obo/UBERON_0001068 skin of back http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A zone of skin that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001070 external carotid artery http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]. http://purl.obolibrary.org/obo/UBERON_0001071 superficial cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery. http://purl.obolibrary.org/obo/UBERON_0001072 inferior vena cava http://purl.obolibrary.org/obo/UBERON_0004087 vena cava A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0001073 ileocecal junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction A point along the course of the gastrointestinal tract where the small intestine (ileum) ends as it opens into the cecal portion of the large intestine; occurs usually within the iliac fossa, demarcated internally as the ileocecal orifice. http://purl.obolibrary.org/obo/UBERON_0001074 pericardial cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity A potential space between the visceral and parietal layers of the pericardium. http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002165 endocardium Endocardium that is part of the cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0001082 epicardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002348 epicardium An epicardial layer that lines a cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002349 myocardium Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer. http://purl.obolibrary.org/obo/UBERON_0001084 skin of head http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin A zone of skin that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001087 pleural fluid http://purl.obolibrary.org/obo/UBERON_0036244 secretion of serous membrane Transudate contained in the pleural cavity. http://purl.obolibrary.org/obo/UBERON_0001090 synovial fluid http://purl.obolibrary.org/obo/UBERON_0007794 secretion of serous gland Joint fluid is a transudate of plasma that is actively secreted by synovial cells. http://purl.obolibrary.org/obo/UBERON_0001092 vertebral bone 1 http://purl.obolibrary.org/obo/UBERON_0002412 vertebra The first vertebral bone in the vertebral column. http://purl.obolibrary.org/obo/UBERON_0001093 vertebral bone 2 http://purl.obolibrary.org/obo/UBERON_0002412 vertebra The second vertebral bone in the vertebral column. http://purl.obolibrary.org/obo/UBERON_0001095 caudal vertebra http://purl.obolibrary.org/obo/UBERON_0018142 caudal vertebra endochondral element Any vertebral bone that is part of the caudal region of the vertebral column (tail or coccyx). http://purl.obolibrary.org/obo/UBERON_0001096 wall of esophagus http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe. http://purl.obolibrary.org/obo/UBERON_0001114 right lobe of liver http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001115 left lobe of liver http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001131 vertebral foramen http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A foramen within a vertebral element through which the spinal cord runs. It is formed by the anterior segment, and the posterior part, the vertebral arch. http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue http://purl.obolibrary.org/obo/UBERON_8600006 visceral striated muscle tissue Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]. http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). http://purl.obolibrary.org/obo/UBERON_0001137 dorsum http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.. http://purl.obolibrary.org/obo/UBERON_0001138 superior mesenteric vein http://purl.obolibrary.org/obo/UBERON_0005617 mesenteric vein In anatomy, the superior mesenteric vein (SMV) is a blood vessel that drains blood from the small intestine. At its termination behind the neck of the pancreas, the SMV combines with the splenic vein to form the hepatic portal vein. The SMV lies to the right of the similarly named artery, the superior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001143 hepatic vein http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel Vein that carries blood away from the liver[ZFA]. http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries. http://purl.obolibrary.org/obo/UBERON_0001152 cystic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct. http://purl.obolibrary.org/obo/UBERON_0001167 wall of stomach http://purl.obolibrary.org/obo/UBERON_0000328 gut wall The layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between. http://purl.obolibrary.org/obo/UBERON_0001168 wall of small intestine http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine An anatomical wall that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001169 wall of large intestine http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine An anatomical wall that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001171 portal lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. http://purl.obolibrary.org/obo/UBERON_0001172 hepatic acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids. http://purl.obolibrary.org/obo/UBERON_0001175 common hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]. http://purl.obolibrary.org/obo/UBERON_0001176 right hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0001177 left hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0001178 visceral peritoneum http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space. http://purl.obolibrary.org/obo/UBERON_0001179 peritoneal cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity Anatomical cavity bounded by visceral and parietal peritoneum. http://purl.obolibrary.org/obo/UBERON_0001190 ovarian artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies an ovary. http://purl.obolibrary.org/obo/UBERON_0001193 hepatic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the liver. http://purl.obolibrary.org/obo/UBERON_0001194 splenic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the spleen. http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa The mucosal layer that lines the stomach. http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract The fibrous connective tissue layer beneath the stomach mucosa. http://purl.obolibrary.org/obo/UBERON_0001201 serosa of stomach http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serosa The outermost layer of the stomach wall, consisting of layers of connective tissue continuous with the peritoneum. http://purl.obolibrary.org/obo/UBERON_0001202 pyloric sphincter http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]. http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa A mucosa that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001205 submucosa of small intestine http://purl.obolibrary.org/obo/UBERON_0009566 intestinal submucosa Submucosal tissue in the small intestines. http://purl.obolibrary.org/obo/UBERON_0001206 serosa of small intestine http://purl.obolibrary.org/obo/UBERON_0001243 serosa of intestine A serous membrane that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa A mucosa that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine http://purl.obolibrary.org/obo/UBERON_0009566 intestinal submucosa A submucosa that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001209 serosa of large intestine http://purl.obolibrary.org/obo/UBERON_0001243 serosa of intestine A serous membrane that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001212 duodenal gland http://purl.obolibrary.org/obo/UBERON_0011148 submucosal gland A compound tubular submucosal gland found in that portion of the duodenum which is above the hepatopancreatic sphincter (Sphincter of Oddi). The main function of these glands is to produce a mucus-rich alkaline secretion (containing bicarbonate)[WP]. http://purl.obolibrary.org/obo/UBERON_0001213 intestinal villus http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The tiny hair-like projections that protrude from the inside of the small intestine that contain blood vessels that capture digested nutrients that are absorbed through the intestinal wall; the villi increase the absorptive surface area of the small intestine by approximately 30-fold. http://purl.obolibrary.org/obo/UBERON_0001215 inferior mesenteric vein http://purl.obolibrary.org/obo/UBERON_0005617 mesenteric vein A blood vessel that drains blood from the large intestine that usually terminates when reaching the splenic vein, which goes on to form the portal vein with the superior mesenteric vein (SMV). Anatomical variations include the IMV draining into the confluence of the SMV and splenic vein and the IMV draining in the SMV. The IMV lies to the right of the similarly name artery, the inferior mesenteric artery, which originates from the abdominal aorta. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001238 lamina propria of small intestine http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria Lamina propria that is part_of the small intestine. http://purl.obolibrary.org/obo/UBERON_0001241 crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/UBERON_0001983 crypt of Lieberkuhn The tubular intestinal glands found in the mucosal membranes of the small intestine. http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa Mucosal layer that lines the intestine. http://purl.obolibrary.org/obo/UBERON_0001243 serosa of intestine http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serosa A serous membrane that is part of a wall of intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001246 interlobular bile duct http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad. http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001263 pancreatic acinus http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0001265 trabecula of spleen http://purl.obolibrary.org/obo/UBERON_0000440 trabecula A trabecula that is part of a spleen. http://purl.obolibrary.org/obo/UBERON_0001268 peritoneal fluid http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid Transudate contained in the peritoneal cavity. http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium The epithelial layer of the stomach . http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium http://purl.obolibrary.org/obo/UBERON_0004808 gastrointestinal system epithelium Epithelial layer that lines the intestine. http://purl.obolibrary.org/obo/UBERON_0001278 epithelium of large intestine http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium An epithelium that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001279 portal triad http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The functional units of the liver including the lobules. http://purl.obolibrary.org/obo/UBERON_0001281 hepatic sinusoid http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel Wide thin-walled blood vessels in the liver. In mammals they have neither veinous or arterial markers. http://purl.obolibrary.org/obo/UBERON_0001282 intralobular bile duct http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct The tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule. http://purl.obolibrary.org/obo/UBERON_0001353 anal region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anus and surrounding regions. Encompasses both internal and external regions, where present. http://purl.obolibrary.org/obo/UBERON_0001366 parietal peritoneum http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane The outer layer of peritoneum that is attached to the abdominal and pelvic walls. http://purl.obolibrary.org/obo/UBERON_0001416 skin of abdomen http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin A zone of skin that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001417 skin of neck http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001418 skin of thorax http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A zone of skin that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001421 pectoral girdle region http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. http://purl.obolibrary.org/obo/UBERON_0001434 skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip http://purl.obolibrary.org/obo/UBERON_1000021 skin of face A zone of skin that is part of a lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001474 bone element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of bone tissue. http://purl.obolibrary.org/obo/UBERON_0001484 articular capsule http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001496 ascending aorta http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0001508 arch of aorta http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery. http://purl.obolibrary.org/obo/UBERON_0001514 descending aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta The part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest. http://purl.obolibrary.org/obo/UBERON_0001516 abdominal aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001529 brachiocephalic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery The short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery. http://purl.obolibrary.org/obo/UBERON_0001530 common carotid artery plus branches http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]. http://purl.obolibrary.org/obo/UBERON_0001533 subclavian artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta. http://purl.obolibrary.org/obo/UBERON_0001534 right subclavian artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The subclavian artery that supplies the right pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0001555 digestive tract http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/UBERON_0001584 left subclavian artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The subclavian artery that supplies the left pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0001586 internal jugular vein http://purl.obolibrary.org/obo/UBERON_0004711 jugular vein One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001592 bronchial vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001605 ciliary muscle http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001607 sphincter pupillae http://purl.obolibrary.org/obo/UBERON_0007521 smooth muscle sphincter A sphincter muscle that is part of the iris. http://purl.obolibrary.org/obo/UBERON_0001608 dilatator pupillae http://purl.obolibrary.org/obo/UBERON_0004234 iris smooth muscle A smooth muscle of the eye, running radially in the iris that functions as a dilator. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001612 facial artery http://purl.obolibrary.org/obo/UBERON_0035398 branch of external carotid artery A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001616 maxillary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. http://purl.obolibrary.org/obo/UBERON_0001639 hepatic portal vein http://purl.obolibrary.org/obo/UBERON_0002017 portal vein A portal vein that transports nutrients from the digestive tract to the liver[Kardong]. http://purl.obolibrary.org/obo/UBERON_0001640 celiac artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery The first major branch of the abdominal aorta. http://purl.obolibrary.org/obo/UBERON_0001651 right pulmonary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The pulmonary artery that supplies the right lung. http://purl.obolibrary.org/obo/UBERON_0001652 left pulmonary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The pulmonary artery that supplies the left lung. http://purl.obolibrary.org/obo/UBERON_0001653 facial vein http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001675 trigeminal ganglion http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The cranial ganglion that is associated with and extends fibers into the trigeminal nerve. http://purl.obolibrary.org/obo/UBERON_0001676 occipital bone http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone The bone at the lower, posterior part of the skull. http://purl.obolibrary.org/obo/UBERON_0001697 orbit of skull http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Subdivision of skeleton that is an anterolateral part of the cranium and structurally supports the eye. Includes bones formed and located in sclerotic layer of eyeball. http://purl.obolibrary.org/obo/UBERON_0001703 neurocranium http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof. http://purl.obolibrary.org/obo/UBERON_0001709 upper jaw region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of head that consists of the upper jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. http://purl.obolibrary.org/obo/UBERON_0001710 lower jaw region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. http://purl.obolibrary.org/obo/UBERON_0001714 cranial ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion The groups of nerve cell bodies associated with the twelve cranial nerves. http://purl.obolibrary.org/obo/UBERON_0001731 cavity of pharynx http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a pharynx. http://purl.obolibrary.org/obo/UBERON_0001766 anterior chamber of eyeball http://purl.obolibrary.org/obo/UBERON_0006311 chamber of eyeball The space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens. http://purl.obolibrary.org/obo/UBERON_0001772 corneal epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium The smooth stratified squamous epithelium that covers the outer surface of the cornea. http://purl.obolibrary.org/obo/UBERON_0001773 sclera http://purl.obolibrary.org/obo/UBERON_0000064 organ part Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]. http://purl.obolibrary.org/obo/UBERON_0001774 skeletal muscle of trunk http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A skeletal muscle organ that is part of the trunk region. http://purl.obolibrary.org/obo/UBERON_0001777 substantia propria of cornea http://purl.obolibrary.org/obo/UBERON_0003891 stroma The lamellated connective tissue of the cornea between the Bowman and Descemet membranes. http://purl.obolibrary.org/obo/UBERON_0001778 ciliary epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A double layer covering the ciliary body that produces aqueous humor. http://purl.obolibrary.org/obo/UBERON_0001779 iris stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae. http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve The any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified]. http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Any of the layers that make up the retina[MP]. http://purl.obolibrary.org/obo/UBERON_0001796 aqueous humor of eyeball http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid A thick watery refractive medium that fills the space between the lens and the cornea[WP]. http://purl.obolibrary.org/obo/UBERON_0001800 sensory ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells. http://purl.obolibrary.org/obo/UBERON_0001801 anterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive). http://purl.obolibrary.org/obo/UBERON_0001802 posterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive). http://purl.obolibrary.org/obo/UBERON_0001803 epithelium of lens http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A layer of epithelial cells that is part of the eye. http://purl.obolibrary.org/obo/UBERON_0001804 capsule of lens http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane The elastic, clear, membrane-like structure, that is outer most layer of the lens. http://purl.obolibrary.org/obo/UBERON_0001805 autonomic ganglion http://purl.obolibrary.org/obo/UBERON_0003338 ganglion of peripheral nervous system Ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion. http://purl.obolibrary.org/obo/UBERON_0001806 sympathetic ganglion http://purl.obolibrary.org/obo/UBERON_0001805 autonomic ganglion A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia. http://purl.obolibrary.org/obo/UBERON_0001884 phrenic nerve http://purl.obolibrary.org/obo/UBERON_0003443 thoracic cavity nerve A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. http://purl.obolibrary.org/obo/UBERON_0001891 midbrain http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. http://purl.obolibrary.org/obo/UBERON_0001892 rhombomere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]. http://purl.obolibrary.org/obo/UBERON_0001895 metencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. http://purl.obolibrary.org/obo/UBERON_0001896 medulla oblongata http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]. http://purl.obolibrary.org/obo/UBERON_0001901 epithelium of trachea http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium The epithelial lining of the trachea which contains numerous ciliated cells. http://purl.obolibrary.org/obo/UBERON_0001902 epithelium of small intestine http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium An epithelium that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001915 endothelium of capillary http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of a capillary [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001916 endothelium of arteriole http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of an arteriole [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium An endothelium that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001918 endothelium of venule http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of a venule [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein http://purl.obolibrary.org/obo/UBERON_0004701 venous system endothelium An endothelium that is part of a vein [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001943 midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. http://purl.obolibrary.org/obo/UBERON_0001948 regional part of spinal cord http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system A multi-tissue structure that is part of a spinal cord. http://purl.obolibrary.org/obo/UBERON_0001956 cartilage of bronchus http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]. http://purl.obolibrary.org/obo/UBERON_0001957 submucosa of bronchus http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001969 blood plasma http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid The liquid component of blood, in which erythrocytes are suspended. http://purl.obolibrary.org/obo/UBERON_0001970 bile http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium. http://purl.obolibrary.org/obo/UBERON_0001972 submucosa of esophagus http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract A submucosa that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001974 lamina propria of esophagus http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001975 serosa of esophagus http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001976 epithelium of esophagus http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium The epithelial layer that lines the luminal space of the esophagus. http://purl.obolibrary.org/obo/UBERON_0001979 venule http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins. http://purl.obolibrary.org/obo/UBERON_0001980 arteriole http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel The smallest division of the artery located between the muscular arteries and the capillaries[GO]. http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel through which blood circulates in the body. http://purl.obolibrary.org/obo/UBERON_0001983 crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0000333 intestinal gland The tubular intestinal glands found in the mucosal membranes. http://purl.obolibrary.org/obo/UBERON_0001984 crypt of Lieberkuhn of large intestine http://purl.obolibrary.org/obo/UBERON_0001983 crypt of Lieberkuhn A crypt of Lieberkühn that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001985 corneal endothelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]. http://purl.obolibrary.org/obo/UBERON_0001986 endothelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]. http://purl.obolibrary.org/obo/UBERON_0001988 feces http://purl.obolibrary.org/obo/UBERON_0000174 excreta Portion of semisolid bodily waste discharged through the anus[MW,modified]. http://purl.obolibrary.org/obo/UBERON_0001994 hyaline cartilage tissue http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance. http://purl.obolibrary.org/obo/UBERON_0002017 portal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]. http://purl.obolibrary.org/obo/UBERON_0002020 gray matter http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons. http://purl.obolibrary.org/obo/UBERON_0002028 hindbrain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. http://purl.obolibrary.org/obo/UBERON_0002029 epithelium of gall bladder http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system The simple columnar epithelial lining of the gall bladder. http://purl.obolibrary.org/obo/UBERON_0002031 epithelium of bronchus http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium An epithelium that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue that contains fibers that are divided by transverse bands into striations. http://purl.obolibrary.org/obo/UBERON_0002040 bronchial artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A systemic artery that supplies the lung with with oxygenated blood. http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anatomical structure that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0002057 phrenic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that supplies the diaphragm. http://purl.obolibrary.org/obo/UBERON_0002061 truncus arteriosus http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles. http://purl.obolibrary.org/obo/UBERON_0002062 endocardial cushion http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002063 sinus venosus http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart. http://purl.obolibrary.org/obo/UBERON_0002072 hypodermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. http://purl.obolibrary.org/obo/UBERON_0002075 viscus http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen. http://purl.obolibrary.org/obo/UBERON_0002078 right cardiac atrium http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve. http://purl.obolibrary.org/obo/UBERON_0002079 left cardiac atrium http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve. http://purl.obolibrary.org/obo/UBERON_0002080 heart right ventricle http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber A cardiac ventricle that is in the right side of the heart. http://purl.obolibrary.org/obo/UBERON_0002081 cardiac atrium http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber Cardiac chamber in which blood enters the heart. http://purl.obolibrary.org/obo/UBERON_0002082 cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber Cardiac chamber through which blood leaves the heart. http://purl.obolibrary.org/obo/UBERON_0002084 heart left ventricle http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber A cardiac ventricle that is in the left side of the heart. http://purl.obolibrary.org/obo/UBERON_0002085 interatrial septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum A cardiac septum that divides the left and right atria of the heart. http://purl.obolibrary.org/obo/UBERON_0002090 postcranial axial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. http://purl.obolibrary.org/obo/UBERON_0002091 appendicular skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]. http://purl.obolibrary.org/obo/UBERON_0002094 interventricular septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum Cardiac septum which separates the right ventricle from the left ventricle.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002097 skin of body http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The organ covering the body that consists of the dermis and epidermis. http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum http://purl.obolibrary.org/obo/UBERON_0003037 septum The thin membranous structure between the two heart atria or the thick muscular structure between the two heart ventricles. http://purl.obolibrary.org/obo/UBERON_0002100 trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. http://purl.obolibrary.org/obo/UBERON_0002104 visual system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system subserving the sense of vision. http://purl.obolibrary.org/obo/UBERON_0002105 vestibulo-auditory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system Sensory system responsible for the perception of spatial orientation and auditory stimuli. http://purl.obolibrary.org/obo/UBERON_0002111 artery smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002112 smooth muscle of esophagus http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002118 right ovary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An ovary that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002119 left ovary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An ovary that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002128 superior olivary complex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. http://purl.obolibrary.org/obo/UBERON_0002148 locus ceruleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]. http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703). http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium http://purl.obolibrary.org/obo/UBERON_0002165 endocardium Endocardium that is part of the atrium. http://purl.obolibrary.org/obo/UBERON_0002167 right lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002168 left lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the left upper lobe and left lower lobe.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002190 subcutaneous adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue A portion of adipose tissue that is part of the hypodermis, beneath the dermis. http://purl.obolibrary.org/obo/UBERON_0002193 hemolymphoid system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. http://purl.obolibrary.org/obo/UBERON_0002199 integument http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The dermis, epidermis and hypodermis. http://purl.obolibrary.org/obo/UBERON_0002200 vasculature of head http://purl.obolibrary.org/obo/UBERON_0002049 vasculature Vasculature that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002201 vasculature of trunk http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002202 submucosa of trachea http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ Vasculature that is part of the eye region. http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002224 thoracic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the coelemic cavity lumen that is enclosed by the walls of the thorax. http://purl.obolibrary.org/obo/UBERON_0002241 chondrocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]. http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]. http://purl.obolibrary.org/obo/UBERON_0002275 reticular formation http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 ). http://purl.obolibrary.org/obo/UBERON_0002294 biliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree). http://purl.obolibrary.org/obo/UBERON_0002302 myocardium of atrium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium The atrial part of middle layer of the heart, comprised of involuntary muscle. http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A neural nucleus that is part of the brain. http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002020 gray matter The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue. http://purl.obolibrary.org/obo/UBERON_0002323 coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities. http://purl.obolibrary.org/obo/UBERON_0002324 muscle of back http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element Any muscle organ that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002328 notochord http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. http://purl.obolibrary.org/obo/UBERON_0002329 somite http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0002333 pulmonary trunk http://purl.obolibrary.org/obo/UBERON_0001637 artery An arterial trunk which is continuous with the heart and branches into the pulmonary arteries. http://purl.obolibrary.org/obo/UBERON_0002338 lamina propria of bronchus http://purl.obolibrary.org/obo/UBERON_0000031 lamina propria of trachea A lamina propria that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002342 neural crest http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. http://purl.obolibrary.org/obo/UBERON_0002343 abdomen musculature http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk Set of all muscles in abdomen. http://purl.obolibrary.org/obo/UBERON_0002345 descending thoracic aorta http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest. http://purl.obolibrary.org/obo/UBERON_0002346 neurectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Embryonic ectoderm that gives rise to nervous tissue. http://purl.obolibrary.org/obo/UBERON_0002347 thoracic vertebra http://purl.obolibrary.org/obo/UBERON_0015008 thoracic vertebra endochondral element A thoracic vertebra endochondral element that is composed primarily of a bone tissue. http://purl.obolibrary.org/obo/UBERON_0002350 conducting system of heart http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]. http://purl.obolibrary.org/obo/UBERON_0002352 atrioventricular node http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles. http://purl.obolibrary.org/obo/UBERON_0002354 cardiac Purkinje fiber http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. http://purl.obolibrary.org/obo/UBERON_0002357 serous pericardium http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane Serous membrane which is divided into parietal and visceral serous pericardium. http://purl.obolibrary.org/obo/UBERON_0002359 fibrous pericardium http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas. http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle Any skeletal muscle that is part of the head region. http://purl.obolibrary.org/obo/UBERON_0002377 muscle of neck http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle Any muscle that is part of the cervical (neck) region. http://purl.obolibrary.org/obo/UBERON_0002378 muscle of abdomen http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis. http://purl.obolibrary.org/obo/UBERON_0002396 vomer http://purl.obolibrary.org/obo/UBERON_0012071 palate bone The triangular flat bone of the nasal septum. http://purl.obolibrary.org/obo/UBERON_0002400 parietal pleura http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The outer serous membrane of the pulmonary pleural. http://purl.obolibrary.org/obo/UBERON_0002401 visceral pleura http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs. http://purl.obolibrary.org/obo/UBERON_0002402 pleural cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity The fluid-filled cavity that lies between the visceral and parietal pleurae. http://purl.obolibrary.org/obo/UBERON_0002406 pericardial sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A double-walled sac containing the heart and the roots of the great vessels. http://purl.obolibrary.org/obo/UBERON_0002408 parietal serous pericardium http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac. http://purl.obolibrary.org/obo/UBERON_0002409 pericardial fluid http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid Transudate contained in the pericardial cavity.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002412 vertebra http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0002413 cervical vertebra http://purl.obolibrary.org/obo/UBERON_0015007 cervical vertebra endochondral element A vertebra that is located in the cervical region of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0002415 tail http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail. http://purl.obolibrary.org/obo/UBERON_0002417 abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The abdominal segment of the torso. http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. http://purl.obolibrary.org/obo/UBERON_0002419 skin gland http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa A gland that is part of a skin of body [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002423 hepatobiliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The part of the digestive system that contains the liver and the biliary system. http://purl.obolibrary.org/obo/UBERON_0002424 oral epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues. http://purl.obolibrary.org/obo/UBERON_0002425 visceral serous pericardium http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]. http://purl.obolibrary.org/obo/UBERON_0002443 choroidal blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a choroid [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002457 intersomitic artery http://purl.obolibrary.org/obo/UBERON_0014907 intersomitic vessel The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries. http://purl.obolibrary.org/obo/UBERON_0002458 spinal artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery Arteries that supply the spinal cord. http://purl.obolibrary.org/obo/UBERON_0002466 intestine secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland Clear to pale yellow watery secretions from the glands lining the small intestine walls. Secretion is stimulated by the mechanical pressure of partly digested food in the intestine. http://purl.obolibrary.org/obo/UBERON_0002469 esophagus mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. http://purl.obolibrary.org/obo/UBERON_0002506 iris epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea http://purl.obolibrary.org/obo/UBERON_0000440 trabecula The supporting bundles of muscular fibers lining the walls of the ventricles of the heart. http://purl.obolibrary.org/obo/UBERON_0002513 endochondral bone http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element Replacement bone that forms within cartilage. http://purl.obolibrary.org/obo/UBERON_0002514 intramembranous bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. http://purl.obolibrary.org/obo/UBERON_0002517 basicranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The base of skull is the most inferior area of the skull, composed of the endocranium and lower parts of the skull roof. http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue composed of elastic fibers. http://purl.obolibrary.org/obo/UBERON_0002522 tunica media http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer The middle layer of an artery or vein. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002523 tunica intima http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]. http://purl.obolibrary.org/obo/UBERON_0002530 gland http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that functions as a secretory or excretory organ. http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002533 post-anal tail bud http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The rapidly proliferating mass of cells at the caudal extremity of the embryo; remnant of the primitive node. http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum http://purl.obolibrary.org/obo/UBERON_0000020 sense organ Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]. http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. http://purl.obolibrary.org/obo/UBERON_0002546 cranial placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. http://purl.obolibrary.org/obo/UBERON_0002548 larva http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism A distinct juvenile form many animals undergo before metamorphosis into adults. Animals with indirect development such as insects, amphibians, or cnidarians typically have a larval phase of their life cycle. http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. http://purl.obolibrary.org/obo/UBERON_0002561 lumen of central nervous system http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube. http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. http://purl.obolibrary.org/obo/UBERON_0002726 cervical spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment A spinal cord segment that adjacent_to a cervical region. http://purl.obolibrary.org/obo/UBERON_0002925 trigeminal nucleus http://purl.obolibrary.org/obo/UBERON_0000126 cranial nerve nucleus A nucleus of brain that is part of a trigeminal nuclear complex. http://purl.obolibrary.org/obo/UBERON_0003023 pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0000064 organ part Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133). http://purl.obolibrary.org/obo/UBERON_0003037 septum http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A wall, dividing a cavity or structure into smaller ones[WP]. http://purl.obolibrary.org/obo/UBERON_0003038 thoracic spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0003052 midbrain-hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/UBERON_0003055 periderm http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outermost layer (or layers, depending on the species) of embryonic skin, essential for the development of the epidermis and establishment of the barrier functions. The periderm derives from the outer layer of the ectoderm. http://purl.obolibrary.org/obo/UBERON_0003056 pre-chordal neural plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The portion of neural plate anterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003057 chordal neural plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The portion of neural plate posterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003059 presomitic mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. http://purl.obolibrary.org/obo/UBERON_0003061 blood island http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. http://purl.obolibrary.org/obo/UBERON_0003063 prechordal plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue. http://purl.obolibrary.org/obo/UBERON_0003064 intermediate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode Lateral neurogenic placodes positioned dorsal of the epibranchial placodes. http://purl.obolibrary.org/obo/UBERON_0003068 axial mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. http://purl.obolibrary.org/obo/UBERON_0003070 trigeminal placode complex http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion. http://purl.obolibrary.org/obo/UBERON_0003072 optic cup http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]. http://purl.obolibrary.org/obo/UBERON_0003073 lens placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]. http://purl.obolibrary.org/obo/UBERON_0003075 neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. http://purl.obolibrary.org/obo/UBERON_0003077 paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. http://purl.obolibrary.org/obo/UBERON_0003078 epibranchial placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. http://purl.obolibrary.org/obo/UBERON_0003081 lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. http://purl.obolibrary.org/obo/UBERON_0003082 myotome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. http://purl.obolibrary.org/obo/UBERON_0003083 trunk neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0003084 heart primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. http://purl.obolibrary.org/obo/UBERON_0003086 caudal artery http://purl.obolibrary.org/obo/UBERON_0003524 tail blood vessel Extension of the dorsal aorta in the tail. http://purl.obolibrary.org/obo/UBERON_0003089 sclerotome http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. http://purl.obolibrary.org/obo/UBERON_0003100 female organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce female gametes. http://purl.obolibrary.org/obo/UBERON_0003102 surface structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. http://purl.obolibrary.org/obo/UBERON_0003103 compound organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme. http://purl.obolibrary.org/obo/UBERON_0003112 olfactory region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that is located in the anterior region of the cranium and provides structural support for the olfactory organ. http://purl.obolibrary.org/obo/UBERON_0003113 dermatocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]. http://purl.obolibrary.org/obo/UBERON_0003115 pharyngeal arch 4 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch Contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus. http://purl.obolibrary.org/obo/UBERON_0003117 pharyngeal arch 6 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles. http://purl.obolibrary.org/obo/UBERON_0003118 pharyngeal arch artery 1 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the first pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003121 pharyngeal arch artery 4 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the fourth pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003123 pharyngeal arch artery 6 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the sixth pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003128 cranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Upper portion of the skull that excludes the mandible (when present in the organism). http://purl.obolibrary.org/obo/UBERON_0003218 ovary septum http://purl.obolibrary.org/obo/UBERON_0003037 septum Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]. http://purl.obolibrary.org/obo/UBERON_0003235 epithelium of upper jaw http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium An epithelium that is part of a upper jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003236 epithelium of lower jaw http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium An epithelium that is part of a lower jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003257 yolk sac endoderm http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium The portion of the yolk sac that is derived from endoderm and lines the yolk sac. http://purl.obolibrary.org/obo/UBERON_0003258 endoderm of foregut http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium An endoderm that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003259 endoderm of midgut http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An endoderm that is part of a midgut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003260 endoderm of hindgut http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An endoderm that is part of a hindgut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003269 skeletal muscle tissue of eye http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003277 skeleton of upper jaw http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton A subdivision of the skeleton that corresponds to the upper part of the mouth. The lower jaw skeleton includes the following elements, when present: upper jaw teeth, the maxilla and other lower jaw bones. http://purl.obolibrary.org/obo/UBERON_0003278 skeleton of lower jaw http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage. http://purl.obolibrary.org/obo/UBERON_0003279 endothelium of trachea http://purl.obolibrary.org/obo/UBERON_0001986 endothelium An endothelium that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003295 pharyngeal gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland Racemose mucous glands beneath the mucous membrane of the pharynx. http://purl.obolibrary.org/obo/UBERON_0003297 gland of integumental system http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a integumental system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003304 mesoderm blood island http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A blood island that is part of a mesoderm. http://purl.obolibrary.org/obo/UBERON_0003314 eye mesenchyme http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme Mesenchyme that is part of a developing camera-type eye. http://purl.obolibrary.org/obo/UBERON_0003315 mesenchyme of ovary http://purl.obolibrary.org/obo/UBERON_0003855 gonad mesenchyme Mesenchyme that is part of a developing ovary [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003316 mesenchyme of yolk sac http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme. http://purl.obolibrary.org/obo/UBERON_0003323 mesenchyme of upper jaw http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme Mesenchyme that is part of a developing upper jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003324 mesenchyme of lower jaw http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme Mesenchyme that is part of a developing lower jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003329 submucosa of anal canal http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine A submucosa that is part of an anal canal [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003330 submucosa of rectum http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine The submucous layer of the wall of the rectum. http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon http://purl.obolibrary.org/obo/UBERON_0001208 submucosa of large intestine A submucosa that is part of a colon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003332 submucosa of duodenum http://purl.obolibrary.org/obo/UBERON_0001205 submucosa of small intestine A submucosa that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003334 serosa of rectum http://purl.obolibrary.org/obo/UBERON_0001209 serosa of large intestine A serous membrane that is part of a rectum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003335 serosa of colon http://purl.obolibrary.org/obo/UBERON_0001209 serosa of large intestine A serous membrane that is part of a colon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003336 serosa of duodenum http://purl.obolibrary.org/obo/UBERON_0001206 serosa of small intestine A serous membrane that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003338 ganglion of peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0000045 ganglion A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO). http://purl.obolibrary.org/obo/UBERON_0003339 ganglion of central nervous system http://purl.obolibrary.org/obo/UBERON_0000045 ganglion A ganglion that is part of a central nervous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003342 mucosa of anal canal http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine A mucosa that is part of an anal canal [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003343 mucosa of oral region http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a oral opening [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003346 mucosa of rectum http://purl.obolibrary.org/obo/UBERON_0001207 mucosa of large intestine A mucosa that is part of a rectum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003350 epithelium of mucosa http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A layer of epithelial cells on the surface of the mucosa. http://purl.obolibrary.org/obo/UBERON_0003351 pharyngeal epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003352 epithelium of midgut http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a midgut. http://purl.obolibrary.org/obo/UBERON_0003353 epithelium of hindgut http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a hindgut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003354 epithelium of rectum http://purl.obolibrary.org/obo/UBERON_0016885 epithelium of terminal part of digestive tract An epithelium that is part of a rectum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003364 epithelium of right lung http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium An epithelium that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003365 epithelium of left lung http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium An epithelium that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003372 pectoral appendage bud ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An unilaminar epithelium that surrounds a pectoral appendage bud. http://purl.obolibrary.org/obo/UBERON_0003379 cardiac muscle of right atrium http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003380 cardiac muscle of left atrium http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003381 cardiac muscle of right ventricle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003382 cardiac muscle of left ventricle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003383 cardiac muscle tissue of interventricular septum http://purl.obolibrary.org/obo/UBERON_0004667 interventricular septum muscular part A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003384 skeletal muscle tissue of pharynx http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003386 smooth muscle of eye http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi. http://purl.obolibrary.org/obo/UBERON_0003387 smooth muscle of trachea http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003388 mesothelium of pericardial cavity http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a pericardium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003389 mesothelium of diaphragm http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium A mesothelium that is part of a diaphragm [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003390 mesothelium of pleural cavity http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a pleural cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003406 cartilage of respiratory system http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage element that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A gland that is part of a digestive tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003413 pectoral appendage bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme Mesenchyme that is part of a pectoral appendage bud. http://purl.obolibrary.org/obo/UBERON_0003426 dermis adipose tissue http://purl.obolibrary.org/obo/UBERON_0003585 dermis connective tissue An adipose tissue that is part of a dermis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003429 abdomen nerve http://purl.obolibrary.org/obo/UBERON_0003825 nerve of abdominal segment A nerve that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003430 neck nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003438 iris nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve Any nerve that innervates the iris. http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk). http://purl.obolibrary.org/obo/UBERON_0003443 thoracic cavity nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is located in a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003452 trabecula carnea cardiac muscle tissue http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a trabecula carnea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003457 head bone http://purl.obolibrary.org/obo/UBERON_0007914 bone of craniocervical region A bone that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003458 neck bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003462 facial bone http://purl.obolibrary.org/obo/UBERON_0003457 head bone A bone that is part of a facial skeleton [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003463 trunk bone http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element A bone that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003469 respiratory system artery http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel An artery that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003470 artery of upper lip http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip The superior labial artery (superior labial branch of facial artery) is larger and more tortuous than the inferior labial artery. It follows a similar course along the edge of the upper lip, lying between the mucous membrane and the Orbicularis oris, and anastomoses with the artery of the opposite side. It supplies the upper lip, and gives off in its course two or three vessels which ascend to the nose; a septal branch ramifies on the nasal septum as far as the point of the nose, and an alar branch supplies the ala of the nose. http://purl.obolibrary.org/obo/UBERON_0003471 artery of lower lip http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery. http://purl.obolibrary.org/obo/UBERON_0003473 thoracic cavity artery http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel An artery that is part of a thoracic cavity[cjm]. http://purl.obolibrary.org/obo/UBERON_0003476 respiratory system venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003477 vein of upper lip http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip The inferior labial vein is the vein receiving blood from the upper lip. http://purl.obolibrary.org/obo/UBERON_0003478 vein of lower lip http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip The inferior labial vein is the vein receiving blood from the lower lip. http://purl.obolibrary.org/obo/UBERON_0003479 thoracic cavity vein http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel A vein that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003481 tail vein http://purl.obolibrary.org/obo/UBERON_0003524 tail blood vessel A vein that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003489 respiratory system capillary endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of capillary that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003494 respiratory system venule http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A venule that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003495 respiratory system arteriole http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel An arteriole that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment blood vessel A blood vessel that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel http://purl.obolibrary.org/obo/UBERON_0005985 coronary vessel A blood vessel that is part of a heart [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003500 corneal blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a cornea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003501 retina blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a retina [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003502 neck blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003505 trachea blood vessel http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A blood vessel that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta. http://purl.obolibrary.org/obo/UBERON_0003511 iris blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003512 lung blood vessel http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel A blood vessel that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003524 tail blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003526 respiratory system capillary http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A capillary that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0002020 gray matter A gray matter that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003534 tail skin http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003567 abdomen connective tissue http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment connective tissue A portion of connective tissue that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003568 neck connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003571 trachea connective tissue http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue A portion of connective tissue that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003585 dermis connective tissue http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A portion of connective tissue that is part of a dermis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003592 bronchus connective tissue http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue A portion of connective tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003593 thoracic cavity connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003599 tail connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a tail [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003601 neck cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage http://purl.obolibrary.org/obo/UBERON_0003406 cartilage of respiratory system A cartilage that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003604 trachea cartilage http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage The ring-shaped cartilaginous structures that support the trachea. http://purl.obolibrary.org/obo/UBERON_0003605 eye skin gland http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region A skin gland that is part of a camera-type eye [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003609 aorta elastic tissue http://purl.obolibrary.org/obo/UBERON_0003614 blood vessel elastic tissue The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall. http://purl.obolibrary.org/obo/UBERON_0003610 heart elastic tissue http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers. http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue An elastic tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003613 cardiovascular system elastic tissue http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue An elastic tissue that is part of a circulatory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003614 blood vessel elastic tissue http://purl.obolibrary.org/obo/UBERON_0003613 cardiovascular system elastic tissue Elastic tissue layer that lines a blood vessel layer. http://purl.obolibrary.org/obo/UBERON_0003615 lung elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue Elastic tissue that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003616 bronchus elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue An elastic tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003617 trachea elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue An elastic tissue that is part of a trachea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003618 aorta tunica media http://purl.obolibrary.org/obo/UBERON_0002522 tunica media The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers. http://purl.obolibrary.org/obo/UBERON_0003619 aorta tunica intima http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer The innermost layer of the aorta, containing the endothelium and an inner elastic membrane. http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An arterial blood vessel that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003665 post-anal tail muscle http://purl.obolibrary.org/obo/UBERON_0004518 muscle of vertebral column A muscle organ that attaches to a tail vertebra [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003684 abdominal cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity). http://purl.obolibrary.org/obo/UBERON_0003694 atlanto-axial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint The Atlanto-axial joint is of a complicated nature, comprising no fewer than four distinct joints. There is a pivot articulation between the odontoid process of the axis and the ring formed by the anterior arch and the transverse ligament of the atlas. http://purl.obolibrary.org/obo/UBERON_0003697 abdominal wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles. http://purl.obolibrary.org/obo/UBERON_0003711 brachiocephalic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava. http://purl.obolibrary.org/obo/UBERON_0003713 splenic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein arising from the splenic trabecular vein in the hilum of the spleen that drains into the portal vein. http://purl.obolibrary.org/obo/UBERON_0003714 neural tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. http://purl.obolibrary.org/obo/UBERON_0003715 splanchnic nerve http://purl.obolibrary.org/obo/UBERON_0034729 sympathetic nerve The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia. http://purl.obolibrary.org/obo/UBERON_0003726 thoracic nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls. http://purl.obolibrary.org/obo/UBERON_0003727 intercostal nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucous membrane that lines the mouth. http://purl.obolibrary.org/obo/UBERON_0003824 nerve of thoracic segment http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region A nerve that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003825 nerve of abdominal segment http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region A nerve that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003827 thoracic segment bone http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ A bone that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003828 abdominal segment bone http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element A bone that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003830 thoracic segment muscle http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ Any muscle organ that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Any muscle organ that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003832 esophagus muscle http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any muscle organ that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003833 abdominal segment muscle http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel A blood vessel that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment blood vessel http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue A portion of connective tissue that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment connective tissue http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003842 neural tube lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a neural tube. http://purl.obolibrary.org/obo/UBERON_0003848 gonadal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0003849 mesencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a midbrain. http://purl.obolibrary.org/obo/UBERON_0003852 rhombencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a hindbrain. http://purl.obolibrary.org/obo/UBERON_0003853 spinal cord neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a spinal cord. http://purl.obolibrary.org/obo/UBERON_0003854 spinal cord neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a future spinal cord. http://purl.obolibrary.org/obo/UBERON_0003855 gonad mesenchyme http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Mesenchyme that is part of a developing gonad [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003869 presumptive ganglion http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a ganglion. http://purl.obolibrary.org/obo/UBERON_0003886 future coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that has the potential to develop into a coelemic cavity lumen. http://purl.obolibrary.org/obo/UBERON_0003887 intraembryonic coelom http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. http://purl.obolibrary.org/obo/UBERON_0003891 stroma http://purl.obolibrary.org/obo/UBERON_0000064 organ part Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma. http://purl.obolibrary.org/obo/UBERON_0003894 liver primordium http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum. http://purl.obolibrary.org/obo/UBERON_0003897 axial muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate One of the skeletal muscles of the head and neck, spine, and ribs. http://purl.obolibrary.org/obo/UBERON_0003898 skeletal muscle tissue of trunk http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue in the trunk. http://purl.obolibrary.org/obo/UBERON_0003902 retinal neural layer http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The part of the retina that contains neurons and photoreceptor cells[GO]. http://purl.obolibrary.org/obo/UBERON_0003909 sinusoid http://purl.obolibrary.org/obo/UBERON_2005260 fenestrated capillary Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]. http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/UBERON_0003915 endothelial tube http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube Any endothelium that has the quality of being cylindrical [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that carries blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/UBERON_0003921 pancreas primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that develops into pancreatic bud. http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. http://purl.obolibrary.org/obo/UBERON_0003923 dorsal pancreatic bud http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud Pancreatic bud that gives rise to the accessory pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0003924 ventral pancreatic bud http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud Pancreatic bud that gives rise to the major pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0003928 digestive system duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that lines the lumen of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0003932 cartilage element of chondrocranium http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage A cartilage element of chondrocranium. Example: neurocranial trabecula. http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage element that is part of the cranial skeleton. http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. http://purl.obolibrary.org/obo/UBERON_0003942 somatosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system for the sense of touch and pain. http://purl.obolibrary.org/obo/UBERON_0003952 anterior stroma of cornea http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue The anterior segment of the lamellated connective tissue layer of the cornea. http://purl.obolibrary.org/obo/UBERON_0003953 posterior stroma of cornea http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue The posterior segment of the lamellated connective tissue layer of the cornea. http://purl.obolibrary.org/obo/UBERON_0003967 cutaneous elastic tissue http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity. http://purl.obolibrary.org/obo/UBERON_0003975 internal female genitalia http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina. http://purl.obolibrary.org/obo/UBERON_0004015 embryonic-extraembryonic boundary http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary The connection between the embryo proper and extraembryonic tissues. http://purl.obolibrary.org/obo/UBERON_0004016 dermatome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. http://purl.obolibrary.org/obo/UBERON_0004022 germinal neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells. http://purl.obolibrary.org/obo/UBERON_0004058 biliary ductule http://purl.obolibrary.org/obo/UBERON_0000025 tube One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP]. http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer. http://purl.obolibrary.org/obo/UBERON_0004062 neural tube marginal layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter. http://purl.obolibrary.org/obo/UBERON_0004064 neural tube basal plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons. http://purl.obolibrary.org/obo/UBERON_0004066 frontonasal prominence http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process The unpaired embryonic prominence that is formed by the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout. http://purl.obolibrary.org/obo/UBERON_0004068 medial nasal prominence http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process The central area of the two limbs of a horseshoe-shaped mesenchymal swelling that lie medial to the olfactory placode or pit in the future nasal region of the embryo; it joins with the ipsilateral maxillary prominence in the formation of half of the upper jaw, and the nasal tip and philtrum of the upper lip develop from it. http://purl.obolibrary.org/obo/UBERON_0004087 vena cava http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0004088 orbital region http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present. http://purl.obolibrary.org/obo/UBERON_0004089 midface http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The middle of the face including the nose and its associated bony structures[MW]. http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any tube, opening or passage that connects two distinct anatomical spaces. http://purl.obolibrary.org/obo/UBERON_0004118 vasculature of iris http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye A vasculature that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the endoderm. http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the mesoderm. http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the ectoderm. http://purl.obolibrary.org/obo/UBERON_0004122 genitourinary system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction. http://purl.obolibrary.org/obo/UBERON_0004123 myocardial layer http://purl.obolibrary.org/obo/UBERON_0005983 heart layer Any of the layers of the myocardium. Example: compact layer, trabecular layer. http://purl.obolibrary.org/obo/UBERON_0004124 myocardium trabecular layer http://purl.obolibrary.org/obo/UBERON_0004123 myocardial layer The layer of the myocardium composed of projections of contractile myocytes. The trabecular layer is bounded internally by the endocardium. In zebrafish, unlike the trabeculations of higher vertebrates, both atrial and ventricular trabeculae have more strut-like character, and are more uniform without apparent regional differences[ZFA]. http://purl.obolibrary.org/obo/UBERON_0004126 trabecular layer of ventricle http://purl.obolibrary.org/obo/UBERON_0004124 myocardium trabecular layer A myocardium trabecular layer that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0004128 optic vesicle http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. http://purl.obolibrary.org/obo/UBERON_0004133 salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Missing definition for term UBERON:0004133. Please replace it using linked reference. http://purl.obolibrary.org/obo/UBERON_0004139 cardiogenic plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The first recognizable structure derived from the heart field. http://purl.obolibrary.org/obo/UBERON_0004140 primary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. http://purl.obolibrary.org/obo/UBERON_0004141 heart tube http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/UBERON_0004142 outflow tract septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum The outflow tract septum is a partition in the outflow tract. http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/UBERON_0004146 His-Purkinje system http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/UBERON_0004148 cardiac vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein Vein of heart that drains the myocardium. http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber http://purl.obolibrary.org/obo/UBERON_0000064 organ part A cardiac chamber surrounds an enclosed cavity within the heart. http://purl.obolibrary.org/obo/UBERON_0004160 proepicardium http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium. http://purl.obolibrary.org/obo/UBERON_0004161 septum transversum http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]. http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The external genitalia are the outer sex organs, such as the penis or vulva in mammals. http://purl.obolibrary.org/obo/UBERON_0004177 hemopoietic organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ that is part of the hematopoietic system. http://purl.obolibrary.org/obo/UBERON_0004178 aorta smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle The nonstriated, involuntary muscle tissue located in the wall of the aorta. http://purl.obolibrary.org/obo/UBERON_0004185 endodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portions of the gut that is derived from endoderm. http://purl.obolibrary.org/obo/UBERON_0004215 back nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004220 large intestine smooth muscle http://purl.obolibrary.org/obo/UBERON_0004221 intestine smooth muscle A portion of smooth muscle tissue that is part of a large intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004221 intestine smooth muscle http://purl.obolibrary.org/obo/UBERON_0004226 gastrointestinal system smooth muscle A portion of smooth muscle tissue that is part of a intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004222 stomach smooth muscle http://purl.obolibrary.org/obo/UBERON_0004226 gastrointestinal system smooth muscle A portion of smooth muscle tissue that is part of a stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004225 respiratory system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004226 gastrointestinal system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004231 anal region smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of an anal region [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle http://purl.obolibrary.org/obo/UBERON_0004225 respiratory system smooth muscle A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004234 iris smooth muscle http://purl.obolibrary.org/obo/UBERON_0003386 smooth muscle of eye A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004236 arteriole smooth muscle http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Smooth muscle found within, and composing the majority of the wall of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004238 spleen smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a spleen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004239 small intestine smooth muscle http://purl.obolibrary.org/obo/UBERON_0004221 intestine smooth muscle A portion of smooth muscle tissue that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004240 gallbladder smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004242 bronchus smooth muscle http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004246 outflow tract smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004247 bone of dorsum http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element A bone that is part of the dorsal region of an animal. http://purl.obolibrary.org/obo/UBERON_0004253 skin muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Any muscle organ that is part of a skin of body [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004258 back blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004265 outflow tract myocardium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium A myocardium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004267 back connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004271 outflow tract pericardium http://purl.obolibrary.org/obo/UBERON_0002407 pericardium A pericardium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle that is part of the eye region. http://purl.obolibrary.org/obo/UBERON_0004288 skeleton http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. http://purl.obolibrary.org/obo/UBERON_0004290 dermomyotome http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure The bilaminar epithelium formed from the myotome and dermatome. http://purl.obolibrary.org/obo/UBERON_0004291 heart rudiment http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/UBERON_0004292 cardiac skeleton http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart. http://purl.obolibrary.org/obo/UBERON_0004297 respiratory system blood vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004345 trophectoderm http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition. http://purl.obolibrary.org/obo/UBERON_0004348 optic eminence http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic structure that gives rise to the corneal ectoderm. http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/UBERON_0004362 pharyngeal arch 1 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries. http://purl.obolibrary.org/obo/UBERON_0004364 ectoplacental cone http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta. http://purl.obolibrary.org/obo/UBERON_0004365 vitelline blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel Blood vessel that is connected to the yolk sac. http://purl.obolibrary.org/obo/UBERON_0004367 Descemet's membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. http://purl.obolibrary.org/obo/UBERON_0004370 anterior limiting lamina of cornea http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane. http://purl.obolibrary.org/obo/UBERON_0004374 vitelline vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature Vascular network that is connected to the yolk sac. http://purl.obolibrary.org/obo/UBERON_0004375 bone of free limb or fin http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of an appendage [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004451 trunk or cervical vertebra http://purl.obolibrary.org/obo/UBERON_0002412 vertebra A vertebra in the trunk or cervical region. Includes all cervical, thoracic and lumbar vertebrae, but excludes caudal vertebra. http://purl.obolibrary.org/obo/UBERON_0004455 neurula embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo An embryo at the neurula stage. http://purl.obolibrary.org/obo/UBERON_0004456 entire sense organ system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Sum of all sensory systems in an organism. http://purl.obolibrary.org/obo/UBERON_0004461 skeletal musculature of head http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature Any collection of skeletal muscles that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004464 musculature of thorax http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk Any collection of muscles that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004465 musculature of neck http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004469 musculature of back http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004471 musculature of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles. http://purl.obolibrary.org/obo/UBERON_0004473 musculature of face http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature Any collection of muscles that is part of a face. http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004491 cardiac muscle tissue of interatrial septum http://purl.obolibrary.org/obo/UBERON_0004492 cardiac muscle tissue of cardiac septum A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004492 cardiac muscle tissue of cardiac septum http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004495 skeletal muscle tissue of diaphragm http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004518 muscle of vertebral column http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A muscle that is attached to a vertebra of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0004521 vasculature of muscle organ http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a muscle organ [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004522 vasculature of musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a musculoskeletal system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004525 cardiac muscle tissue of trabecula carnea of right ventricle http://purl.obolibrary.org/obo/UBERON_0003452 trabecula carnea cardiac muscle tissue A portion of trabecula carnea cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004526 cardiac muscle tissue of trabecula carnea of left ventricle http://purl.obolibrary.org/obo/UBERON_0003452 trabecula carnea cardiac muscle tissue A portion of trabecula carnea cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vascular network consisting of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004548 left eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An eye that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004549 right eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An eye that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004571 systemic arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart. http://purl.obolibrary.org/obo/UBERON_0004572 arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all arteries. http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart. http://purl.obolibrary.org/obo/UBERON_0004581 systemic venous system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the venous system that drains the general body tissues[Kardong]. http://purl.obolibrary.org/obo/UBERON_0004582 venous system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions. http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. http://purl.obolibrary.org/obo/UBERON_0004647 liver lobule http://purl.obolibrary.org/obo/UBERON_0000064 organ part The polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein. http://purl.obolibrary.org/obo/UBERON_0004663 aorta wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel An anatomical wall that is part of an aorta, enclosing the luminal space. http://purl.obolibrary.org/obo/UBERON_0004664 aorta tunica adventitia http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel The outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers. http://purl.obolibrary.org/obo/UBERON_0004666 interventricular septum membranous part http://purl.obolibrary.org/obo/UBERON_0005983 heart layer The membranous portion of the wall between the two lower chambers of the heart. http://purl.obolibrary.org/obo/UBERON_0004667 interventricular septum muscular part http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue The muscular portion of the wall between the two lower chambers of the heart. http://purl.obolibrary.org/obo/UBERON_0004684 raphe nuclei http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane. http://purl.obolibrary.org/obo/UBERON_0004688 costo-cervical trunk http://purl.obolibrary.org/obo/UBERON_0001637 artery The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004698 vena cava endothelium http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein An endothelium that is part of a vena cava [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004699 outflow tract endothelium http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium An endothelium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of an arterial system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004701 venous system endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of a venous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004706 bulbus cordis http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches. http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An appendage that is part of an appendage girdle complex. http://purl.obolibrary.org/obo/UBERON_0004710 pectoral appendage http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues. http://purl.obolibrary.org/obo/UBERON_0004711 jugular vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava. http://purl.obolibrary.org/obo/UBERON_0004716 conceptus http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. http://purl.obolibrary.org/obo/UBERON_0004729 nematode larval stage http://purl.obolibrary.org/obo/UBERON_0000069 larval stage Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. http://purl.obolibrary.org/obo/UBERON_0004731 neuromere http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres). http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres. http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system An organ subunit that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004734 gastrula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the gastrula stage. http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. http://purl.obolibrary.org/obo/UBERON_0004756 dermal skeletal element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Dermis-derived entity that is made of skeletal tissue. http://purl.obolibrary.org/obo/UBERON_0004757 rectal salt gland http://purl.obolibrary.org/obo/UBERON_0004758 salt gland An evagination of the terminal portion of the intestine that is capable of secreting high concentrations of excess sodium chloride. http://purl.obolibrary.org/obo/UBERON_0004758 salt gland http://purl.obolibrary.org/obo/UBERON_0002530 gland An organ for excreting excess salts. It is found in elasmobranchs, seabirds, and some reptiles.[WP]. http://purl.obolibrary.org/obo/UBERON_0004759 cranial salt gland http://purl.obolibrary.org/obo/UBERON_0004758 salt gland A salt gland located in the cranium or head region. http://purl.obolibrary.org/obo/UBERON_0004760 gland of anal canal http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of an anal canal [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004761 cartilaginous neurocranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]. http://purl.obolibrary.org/obo/UBERON_0004764 intramembranous bone tissue http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. http://purl.obolibrary.org/obo/UBERON_0004766 cranial bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a cranium. http://purl.obolibrary.org/obo/UBERON_0004768 bone of lower jaw http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular. http://purl.obolibrary.org/obo/UBERON_0004770 articular system http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical system that consists of all the joints of the body. http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa http://purl.obolibrary.org/obo/UBERON_0000009 submucosa A submucosa that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004779 respiratory system lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a gastrointestinal system. http://purl.obolibrary.org/obo/UBERON_0004781 gallbladder lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004782 gastrointestinal system serosa http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004783 gallbladder serosa http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa The mucous membrane lining the respiratory tract. http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a gastrointestinal system. http://purl.obolibrary.org/obo/UBERON_0004790 skin mucous gland http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system A mucous gland that is part of the skin. http://purl.obolibrary.org/obo/UBERON_0004792 secretion of endocrine pancreas http://purl.obolibrary.org/obo/UBERON_0004795 pancreas secretion A secretion that is part of a endocrine pancreas [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004793 secretion of exocrine pancreas http://purl.obolibrary.org/obo/UBERON_0004795 pancreas secretion A secretion that is part of a exocrine pancreas [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004794 esophagus secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A secretion that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004795 pancreas secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A secretion that is part of a pancreas [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia. http://purl.obolibrary.org/obo/UBERON_0004798 respiratory system basal lamina http://purl.obolibrary.org/obo/UBERON_0000482 basal lamina of epithelium A basal lamina that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004799 trachea basal lamina http://purl.obolibrary.org/obo/UBERON_0004798 respiratory system basal lamina A basal lamina that is part of a respiratory airway [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004800 bronchus basal lamina http://purl.obolibrary.org/obo/UBERON_0004799 trachea basal lamina A basal lamina that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi. http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004808 gastrointestinal system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium An epithelium that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004820 bile duct epithelium http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct Any epithelium that lines one of the bile ducts. http://purl.obolibrary.org/obo/UBERON_0004822 extrahepatic bile duct epithelium http://purl.obolibrary.org/obo/UBERON_0004820 bile duct epithelium An epithelium that is part of a extrahepatic bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004823 intrahepatic bile duct epithelium http://purl.obolibrary.org/obo/UBERON_0004820 bile duct epithelium An epithelium that is part of a intrahepatic bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004831 esophagus skeletal muscle http://purl.obolibrary.org/obo/UBERON_0003898 skeletal muscle tissue of trunk A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004832 anal region skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of an anal region [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004833 lip skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004834 hepatic duct smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Smooth muscle tissue in all or part of a hepatic duct. http://purl.obolibrary.org/obo/UBERON_0004848 respiratory system arterial endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of artery that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004849 respiratory system venous endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of vein that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004851 aorta endothelium http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium The thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall. http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium An endothelium that is part of the cardiovascular system. http://purl.obolibrary.org/obo/UBERON_0004857 skeletal muscle connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A connective tissue that surrounds a skeletal muscle tissue. http://purl.obolibrary.org/obo/UBERON_0004859 eye gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid. http://purl.obolibrary.org/obo/UBERON_0004864 vasculature of retina http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina A vasculature that is part of a retina [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004867 orbital cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity bounded by the orbital region of the cranium and forming the location of some or all of the eye. http://purl.obolibrary.org/obo/UBERON_0004872 splanchnic layer of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. http://purl.obolibrary.org/obo/UBERON_0004873 splanchnopleure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]. http://purl.obolibrary.org/obo/UBERON_0004874 somatopleure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. http://purl.obolibrary.org/obo/UBERON_0004880 chordamesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The central region of trunk mesoderm. This tissue forms the notochord. http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The mass of tissue made up of mesenchymal cells in the lung. http://purl.obolibrary.org/obo/UBERON_0004904 neuron projection bundle connecting eye with brain http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila. http://purl.obolibrary.org/obo/UBERON_0004905 articulation http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://purl.obolibrary.org/obo/UBERON_0004906 ectodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portion of the gut that is derived from ectoderm. http://purl.obolibrary.org/obo/UBERON_0004907 lower digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The region of the digestive tract extending from the beginning of the intestines to the anus[GO - gut definition]. http://purl.obolibrary.org/obo/UBERON_0004908 upper digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum. http://purl.obolibrary.org/obo/UBERON_0004909 epithelium of gonad http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An epithelium surrounding a gonad. http://purl.obolibrary.org/obo/UBERON_0004911 epithelium of female gonad http://purl.obolibrary.org/obo/UBERON_0004909 epithelium of gonad An epithelium surrounding an ovary. http://purl.obolibrary.org/obo/UBERON_0004914 duodenal papilla http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0004915 sphincter of hepatopancreatic ampulla http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter Muscular valve that controls the flow of digestive juices (bile and pancreatic juice) through the ampulla of Vater into the second part of the duodenum. Relaxed by the hormone Cholecystokinin (CCK) via vasoactive intestinal polypeptide (VIP).[WP]. http://purl.obolibrary.org/obo/UBERON_0004916 anal sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A sphincter muscle that is part of a anal region. http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A proximal-distal subdivision of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of a wall of an organ that forms a layer. http://purl.obolibrary.org/obo/UBERON_0004924 submucosa of pharynx http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract The tissue underlying the tunica mucosa of the pharynx. http://purl.obolibrary.org/obo/UBERON_0004926 submucosa of cystic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a cystic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004932 submucosa of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0003331 submucosa of colon A submucosa that is part of a sigmoid colon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004934 submucosa of body of stomach http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach A submucosa that is part of a body of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004936 submucosa of pyloric antrum http://purl.obolibrary.org/obo/UBERON_0004937 submucosa of pylorus A submucosa that is part of a pyloric antrum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004937 submucosa of pylorus http://purl.obolibrary.org/obo/UBERON_0001200 submucosa of stomach A submucosa that is part of a pylorus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree http://purl.obolibrary.org/obo/UBERON_0000009 submucosa A submucosa that is part of a biliary tree [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004939 submucosa of common bile duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a common bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004940 submucosa of common hepatic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a common hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004941 submucosa of right hepatic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a right hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004942 submucosa of left hepatic duct http://purl.obolibrary.org/obo/UBERON_0004938 submucosa of biliary tree A submucosa that is part of a left hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004988 mucosa of cystic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a cystic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004993 mucosa of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0000317 colonic mucosa A mucosa that is part of a sigmoid colon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004995 mucosa of body of stomach http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a body of stomach [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004997 mucosa of pyloric antrum http://purl.obolibrary.org/obo/UBERON_0004998 mucosa of pylorus A mucosa that is part of a pyloric antrum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004998 mucosa of pylorus http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a pylorus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a biliary tree [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005000 mucosa of common bile duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a common bile duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005001 mucosa of common hepatic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a common hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005002 mucosa of right hepatic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a right hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005003 mucosa of left hepatic duct http://purl.obolibrary.org/obo/UBERON_0004999 mucosa of biliary tree A mucosa that is part of a left hepatic duct [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005031 mucosa of upper lip http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip A mucosa that is part of a upper lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005032 mucosa of lower lip http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip A mucosa that is part of a lower lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005033 mucosa of gallbladder http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a gallbladder [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005056 external female genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia An external genitalia that is part of a female reproductive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005058 hemolymphoid system gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a hemolymphoid system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005061 neural groove http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds. http://purl.obolibrary.org/obo/UBERON_0005062 neural fold http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of the two elevated edges of the neural groove[GO,MP]. http://purl.obolibrary.org/obo/UBERON_0005064 left ventricular trabecular myocardium http://purl.obolibrary.org/obo/UBERON_0004126 trabecular layer of ventricle Missing definition for term UBERON:0005064. Please replace it using linked reference. http://purl.obolibrary.org/obo/UBERON_0005066 right ventricular trabecular myocardium http://purl.obolibrary.org/obo/UBERON_0004126 trabecular layer of ventricle Missing definition for term UBERON:0005066. Please replace it using linked reference. http://purl.obolibrary.org/obo/UBERON_0005068 neural rod http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]. http://purl.obolibrary.org/obo/UBERON_0005076 hindbrain-spinal cord boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord. http://purl.obolibrary.org/obo/UBERON_0005082 tube lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A hole in a tube[GO]. http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO]. http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold A bud is a protrusion that forms from an epithelial sheet by localized folding. http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any anatomical structure that is part of the reproductive system. http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet bent on a linear axis. http://purl.obolibrary.org/obo/UBERON_0005158 parenchyma of central nervous system http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma The functional tissue of the central nervous system consisting of neurons and glial cells. http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. http://purl.obolibrary.org/obo/UBERON_0005171 hepatic duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion). http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back. http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. http://purl.obolibrary.org/obo/UBERON_0005194 thoracic vein http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel A vein that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005203 trachea gland http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland A tubuloacinar seromucous gland that is located principally in the submucosa of the trachea. Excretory ducts from this gland pass through the lamina propria to the tracheal lumen. http://purl.obolibrary.org/obo/UBERON_0005221 liver right lobe parenchyma http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma A parenchyma that is part of a right lobe of liver [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005222 liver left lobe parenchyma http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma A parenchyma that is part of a left lobe of liver [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005233 medial-nasal process ectoderm http://purl.obolibrary.org/obo/UBERON_0014702 frontonasal process epithelium An ectoderm that is part of a medial nasal prominence [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005234 optic eminence ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a optic eminence [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005243 interventricular septum endocardium http://purl.obolibrary.org/obo/UBERON_0002165 endocardium An endocardium that is part of a interventricular septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005248 bulbus cordis myocardium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium A myocardium that is part of a bulbus cordis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005250 stomatodeum gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a stomodeum. http://purl.obolibrary.org/obo/UBERON_0005251 yolk sac cavity http://purl.obolibrary.org/obo/UBERON_0012466 extraembryonic cavity An anatomical cavity that is part of a yolk sac [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a developing trunk. http://purl.obolibrary.org/obo/UBERON_0005290 myelencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue A portion of tissue that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. http://purl.obolibrary.org/obo/UBERON_0005316 endocardial endothelium http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium The endothelial lining of the endocardium. http://purl.obolibrary.org/obo/UBERON_0005317 pulmonary artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]. http://purl.obolibrary.org/obo/UBERON_0005334 oral lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a mucosa of oral region. http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]. http://purl.obolibrary.org/obo/UBERON_0005338 outflow tract aortic component http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract An outflow tract that is part of a aorta. http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An array of photoreceptors and any supporting cells found in an eye. http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array. http://purl.obolibrary.org/obo/UBERON_0005398 female reproductive gland http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland A sex gland that is part of a female reproductive system. http://purl.obolibrary.org/obo/UBERON_0005419 pectoral appendage bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud A limb bud that develops into a forelimb or pectoral fin. http://purl.obolibrary.org/obo/UBERON_0005421 pectoral appendage apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge An apical ectodermal ridge that is part of a pectoral appendage bud. http://purl.obolibrary.org/obo/UBERON_0005425 presumptive neural retina http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is the inner layer of the optic cup and will become the neural retina. http://purl.obolibrary.org/obo/UBERON_0005426 lens vesicle http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue that gives rise to the lens. http://purl.obolibrary.org/obo/UBERON_0005427 corneal primordium http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. http://purl.obolibrary.org/obo/UBERON_0005428 vagal neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]. http://purl.obolibrary.org/obo/UBERON_0005432 aortic sac http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates. http://purl.obolibrary.org/obo/UBERON_0005436 common hepatic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery In anatomy, the common hepatic artery is a short blood vessel that supplies oxygenated blood to the liver, pylorus (a part of the stomach), duodenum (a part of the small intestine) and pancreas. It arises from the celiac artery and has the following branches:. http://purl.obolibrary.org/obo/UBERON_0005446 foramen rotundum http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull The foramen rotundum is a circular hole in the sphenoid bone that connects the middle cranial fossa and the pterygopalatine fossa. http://purl.obolibrary.org/obo/UBERON_0005460 left vitelline vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vitelline vein that is in the left side of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0005472 right vitelline vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vitelline vein that is in the right side of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube http://purl.obolibrary.org/obo/UBERON_0006846 surface groove A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]. http://purl.obolibrary.org/obo/UBERON_0005487 vitelline vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein The paired veins that carry blood from the yolk sac back to the embryo. http://purl.obolibrary.org/obo/UBERON_0005496 neural tube lateral wall http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Portion of tissue on the side of the lumen of the neural tube. http://purl.obolibrary.org/obo/UBERON_0005498 primitive heart tube http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that arises from the heart rudiment and will become the heart tube. http://purl.obolibrary.org/obo/UBERON_0005501 rhombomere lateral wall http://purl.obolibrary.org/obo/UBERON_0005496 neural tube lateral wall A neural tube lateral wall that is part of a rhombomere. http://purl.obolibrary.org/obo/UBERON_0005563 trigeminal neural crest http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Cranial neural crest which gives rise to the trigeminal ganglion. http://purl.obolibrary.org/obo/UBERON_0005564 gonad primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Portion of tissue that gives rise to the immature gonad. http://purl.obolibrary.org/obo/UBERON_0005594 head somite http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Somite located in the head region, caudal to the otic vesicle. http://purl.obolibrary.org/obo/UBERON_0005597 lung primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum. http://purl.obolibrary.org/obo/UBERON_0005598 trunk somite http://purl.obolibrary.org/obo/UBERON_0002329 somite A somite that is part of a trunk. http://purl.obolibrary.org/obo/UBERON_0005614 lens anterior epithelium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex. http://purl.obolibrary.org/obo/UBERON_0005616 mesenteric artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery Arteries which arise from the abdominal aorta and distribute to most of the intestines. http://purl.obolibrary.org/obo/UBERON_0005617 mesenteric vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that returns blood from the intestines. http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo. http://purl.obolibrary.org/obo/UBERON_0005637 pyloric region epithelium http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach An epithelium that is part of a pylorus. http://purl.obolibrary.org/obo/UBERON_0005638 anterior chamber epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of a anterior chamber of eyeball. http://purl.obolibrary.org/obo/UBERON_0005656 lens vesicle epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a lens vesicle. http://purl.obolibrary.org/obo/UBERON_0005662 4th arch ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/UBERON_0005666 4th arch endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/UBERON_0005669 peritoneal cavity mesothelium http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a peritoneal cavity. http://purl.obolibrary.org/obo/UBERON_0005672 right lung endothelium http://purl.obolibrary.org/obo/UBERON_0003364 epithelium of right lung An endothelium that is part of a right lung. http://purl.obolibrary.org/obo/UBERON_0005673 left lung endothelium http://purl.obolibrary.org/obo/UBERON_0003365 epithelium of left lung An endothelium that is part of a left lung. http://purl.obolibrary.org/obo/UBERON_0005688 lens vesicle cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a lens vesicle. http://purl.obolibrary.org/obo/UBERON_0005691 4th arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/UBERON_0005702 optic eminence mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a optic eminence. http://purl.obolibrary.org/obo/UBERON_0005720 hindbrain venous system http://purl.obolibrary.org/obo/UBERON_0004582 venous system A venous system that is part of a hindbrain. http://purl.obolibrary.org/obo/UBERON_0005729 pectoral appendage field http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme. http://purl.obolibrary.org/obo/UBERON_0005732 paired limb/fin field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A ring of cells capable of forming a limb or paired fin[Gilbert,modified]. http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel http://purl.obolibrary.org/obo/UBERON_0005742 adventitia The outermost layer of a blood vessel, composed mainly of fibrous tissue. http://purl.obolibrary.org/obo/UBERON_0005740 tunica intima of artery http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer A tunica intima that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0005742 adventitia http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An outermost connective tissue covering of an organ, vessel, or other structure[WP]. http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves. http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure An acellular anatomical structure that is the bounding layer of a anatomical structure. http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle. http://purl.obolibrary.org/obo/UBERON_0005805 dorsal aorta http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/UBERON_0005806 portal system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]. http://purl.obolibrary.org/obo/UBERON_0005845 caudal segment of spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment A spinal cord segment that adjacent_to a caudal region. http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation A delimited region of dense mesenchyme within looser mesenchyme. http://purl.obolibrary.org/obo/UBERON_0005863 cartilaginous condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. http://purl.obolibrary.org/obo/UBERON_0005867 mandibular prominence http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence The paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip. http://purl.obolibrary.org/obo/UBERON_0005868 maxillary prominence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The paired dorsal prominences formed by bifurcation of the first pharyngeal arches in the embryo that unite with the ipsilateral medial nasal process to form the upper jaw. http://purl.obolibrary.org/obo/UBERON_0005902 occipital region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles. http://purl.obolibrary.org/obo/UBERON_0005906 serous sac http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]. http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA]. http://purl.obolibrary.org/obo/UBERON_0005944 axial skeleton plus cranial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract An outflow tract that is part of a cardiac atrium. http://purl.obolibrary.org/obo/UBERON_0005953 outflow part of right ventricle http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk. http://purl.obolibrary.org/obo/UBERON_0005956 outflow part of left ventricle http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta. http://purl.obolibrary.org/obo/UBERON_0005965 outflow part of right atrium http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA]. http://purl.obolibrary.org/obo/UBERON_0005966 outflow part of left atrium http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium An outflow tract of atrium that is part of a left atrium. http://purl.obolibrary.org/obo/UBERON_0005979 crista terminalis http://purl.obolibrary.org/obo/UBERON_0000064 organ part The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium. http://purl.obolibrary.org/obo/UBERON_0005983 heart layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The laminar structure of the heart. http://purl.obolibrary.org/obo/UBERON_0005985 coronary vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation. http://purl.obolibrary.org/obo/UBERON_0005988 atrium myocardial trabecula http://purl.obolibrary.org/obo/UBERON_0000440 trabecula The supporting bundles of muscular fibers lining the walls of the atrial myocardium. http://purl.obolibrary.org/obo/UBERON_0005989 atrioventricular septum http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve. http://purl.obolibrary.org/obo/UBERON_0006002 vitelline artery http://purl.obolibrary.org/obo/UBERON_0004365 vitelline blood vessel The paired arteries that carry blood to the yolk sac from the dorsal aorta. http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa http://purl.obolibrary.org/obo/UBERON_0000064 organ part Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers. http://purl.obolibrary.org/obo/UBERON_0006068 bone of tail http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a post-anal tail. http://purl.obolibrary.org/obo/UBERON_0006071 caudal region http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Subdivision of an organism along anterior-posterior axis that is the posteriormost region, extending past the anus (or cloaca, if present), consisting of a tail in some fully formed chordates (or a tail bud in embryos). In animals that have a sacral region, this is the region immediately posterior to this. http://purl.obolibrary.org/obo/UBERON_0006072 cervical region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column That portion of the spine comprising the cervical vertebrae. The neck area of the spine. http://purl.obolibrary.org/obo/UBERON_0006073 thoracic region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column That part of the spine comprising the thoracic vertebrae. http://purl.obolibrary.org/obo/UBERON_0006076 caudal region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column Subdivision of vertebral column that corresponds to the caudal subdivision of the body, containing the caudal vertebrae. http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system A collection of all skeletal elements in some subdivision of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0006207 aortico-pulmonary spiral septum http://purl.obolibrary.org/obo/UBERON_0004142 outflow tract septum The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions. http://purl.obolibrary.org/obo/UBERON_0006211 buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0003037 septum The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx. http://purl.obolibrary.org/obo/UBERON_0006235 foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction An anatomical junctions that overlaps the foregut and midgut. http://purl.obolibrary.org/obo/UBERON_0006238 future brain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic precursor of the brain. http://purl.obolibrary.org/obo/UBERON_0006239 future central tendon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A tendon that has the potential to develop into a central tendon. http://purl.obolibrary.org/obo/UBERON_0006242 gallbladder primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops. http://purl.obolibrary.org/obo/UBERON_0006264 mouth-foregut junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junctions that overlaps the mouth and foregut. http://purl.obolibrary.org/obo/UBERON_0006267 notochordal plate http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. http://purl.obolibrary.org/obo/UBERON_0006268 notochordal process http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. http://purl.obolibrary.org/obo/UBERON_0006271 orbital fissure http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull Either of two openings transmitting nerves and blood vessels to or from the orbit. http://purl.obolibrary.org/obo/UBERON_0006279 pleuroperitoneal canal http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity. http://purl.obolibrary.org/obo/UBERON_0006283 future cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0006293 spleen primordium http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A dense syncitial-like mesenchymal thickening in the dorsal mesogastrium[ISBN]. the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing spleen[MP]. http://purl.obolibrary.org/obo/UBERON_0006311 chamber of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A segment of the eyeball that is filled with refractive media. http://purl.obolibrary.org/obo/UBERON_0006312 ocular refractive media http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Body substance in a liquid or semi-solid state in the eyeball which serves to refract light. http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A nucleus of brain that is part of a brainstem. http://purl.obolibrary.org/obo/UBERON_0006347 communicating artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that connects two larger arteries. http://purl.obolibrary.org/obo/UBERON_0006518 right lung lobe http://purl.obolibrary.org/obo/UBERON_0000101 lobe of lung A lobe of lung that is part of a right lung. http://purl.obolibrary.org/obo/UBERON_0006535 skin secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that secreted_by a zone of skin. http://purl.obolibrary.org/obo/UBERON_0006537 female reproductive gland secretion http://purl.obolibrary.org/obo/UBERON_0022293 reproductive gland secretion A portion of organism substance that is secreted by a female reproductive gland. http://purl.obolibrary.org/obo/UBERON_0006538 respiratory system fluid/secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that secreted_by a respiratory system. http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube that is part of a excretory system. http://purl.obolibrary.org/obo/UBERON_0006563 tunica media of pulmonary trunk http://purl.obolibrary.org/obo/UBERON_0007239 tunica media of artery Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA]. http://purl.obolibrary.org/obo/UBERON_0006566 left ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle A myocardium that is part of a left ventricle of a heart. http://purl.obolibrary.org/obo/UBERON_0006567 right ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle A myocardium that is part of a right ventricle of a heart. http://purl.obolibrary.org/obo/UBERON_0006570 trabecula carnea of right ventricle http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea A trabecula carnea that is part of a heart right ventricle. http://purl.obolibrary.org/obo/UBERON_0006571 trabecula carnea of left ventricle http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea A trabecula carnea that is part of a heart left ventricle. http://purl.obolibrary.org/obo/UBERON_0006574 pectinate line http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction The pectinate line (anocutaneous line, dentate line, anorectal junction) is a line which divides the upper 2/3rds and lower 1/3rd of the anal canal. Developmentally, this line represents the hindgut-proctodeum junction. It is an important anatomical landmark, and several distinctions can be made based upon the location of a structure relative to this line:. http://purl.obolibrary.org/obo/UBERON_0006595 presumptive endoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into endoderm. http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Portion of embryonic tissue determined by fate mapping to become a structure. http://purl.obolibrary.org/obo/UBERON_0006601 presumptive ectoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into ectoderm. http://purl.obolibrary.org/obo/UBERON_0006603 presumptive mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into mesoderm. http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue A region of muscle in many organs in the vertebrate body, adjacent to the submucosa membrane. It is responsible for gut movement such as peristalsis. http://purl.obolibrary.org/obo/UBERON_0006670 central tendon of diaphragm http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers. http://purl.obolibrary.org/obo/UBERON_0006677 surface of epithelium http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical boundary that adjacent_to a epithelium. http://purl.obolibrary.org/obo/UBERON_0006686 spinal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that is part of a vertebral column. http://purl.obolibrary.org/obo/UBERON_0006692 vertebral canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A conduit enclosed within the vertebral foramen of the vertebrae through which the spinal cord passes. http://purl.obolibrary.org/obo/UBERON_0006761 corneo-scleral junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm. http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is composed primarily of secretory cells. http://purl.obolibrary.org/obo/UBERON_0006815 areolar connective tissue http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand. http://purl.obolibrary.org/obo/UBERON_0006828 trabecula carnea of atrium http://purl.obolibrary.org/obo/UBERON_0002511 trabecula carnea The supporting bundles of muscular fibers lining the walls of the atria[MP]. http://purl.obolibrary.org/obo/UBERON_0006833 lumen of trachea http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a trachea. http://purl.obolibrary.org/obo/UBERON_0006834 uterus or analog http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A subdivision of a the reproductive tract in a female organism that is the site of embryo development. http://purl.obolibrary.org/obo/UBERON_0006841 central vein of liver http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel Vein that is central to a lobule in the liver. http://purl.obolibrary.org/obo/UBERON_0006846 surface groove http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A furrow or an incomplete tube. http://purl.obolibrary.org/obo/UBERON_0006866 terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a organ. http://purl.obolibrary.org/obo/UBERON_0006877 vasculature of liver http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a liver. http://purl.obolibrary.org/obo/UBERON_0006904 head mesenchyme from mesoderm http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme A head mesenchyme that develops_from a mesoderm. http://purl.obolibrary.org/obo/UBERON_0006905 mandibular process mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a mandibular prominence. http://purl.obolibrary.org/obo/UBERON_0006909 lumen of digestive tract http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a digestive tract. http://purl.obolibrary.org/obo/UBERON_0006913 lip epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a lip. http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. http://purl.obolibrary.org/obo/UBERON_0006915 stratified squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA]. http://purl.obolibrary.org/obo/UBERON_0006920 esophagus squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium A squamous epithelium that is part of a esophagus. http://purl.obolibrary.org/obo/UBERON_0006921 stomach squamous epithelium http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach A squamous epithelium that is part of a stomach. http://purl.obolibrary.org/obo/UBERON_0006924 stomach glandular epithelium http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands. http://purl.obolibrary.org/obo/UBERON_0006925 digestive system gland http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any gland that is part of the digestive system. http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA]. http://purl.obolibrary.org/obo/UBERON_0006931 stomach glandular region mucosa http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach Stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region. http://purl.obolibrary.org/obo/UBERON_0006934 sensory epithelium http://purl.obolibrary.org/obo/UBERON_0000488 atypical epithelium Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue. http://purl.obolibrary.org/obo/UBERON_0006960 ovary stroma http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. http://purl.obolibrary.org/obo/UBERON_0006965 vascular cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. http://purl.obolibrary.org/obo/UBERON_0006966 coronary capillary http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel A capillary that is part of the coronary system. http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface http://purl.obolibrary.org/obo/UBERON_0010199 bona-fide anatomical boundary A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n. http://purl.obolibrary.org/obo/UBERON_0007005 cardiogenic splanchnic mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. http://purl.obolibrary.org/obo/UBERON_0007010 cleaving embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the cleavage stage. http://purl.obolibrary.org/obo/UBERON_0007098 mandibular neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest Cranial neural crest that migrates into the mandibular arch. http://purl.obolibrary.org/obo/UBERON_0007100 primary circulatory organ http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion Ganglion which is located in the trunk. http://purl.obolibrary.org/obo/UBERON_0007135 neural keel http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. http://purl.obolibrary.org/obo/UBERON_0007144 embryonic post-anal tail http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure An embryonic structure that will either develop into a post-anal tail or recede into a vestigial remnant of the tail. http://purl.obolibrary.org/obo/UBERON_0007147 lumen of midgut http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a midgut. http://purl.obolibrary.org/obo/UBERON_0007148 lumen of hindgut http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a hindgut. http://purl.obolibrary.org/obo/UBERON_0007158 lumen of anal canal http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a anal canal. http://purl.obolibrary.org/obo/UBERON_0007159 lumen of colon http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a colon. http://purl.obolibrary.org/obo/UBERON_0007177 lamina propria of mucosa of colon http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine A lamina propria that is part of a colonic mucosa. http://purl.obolibrary.org/obo/UBERON_0007188 mesothelium of serous pericardium http://purl.obolibrary.org/obo/UBERON_0003388 mesothelium of pericardial cavity A mesothelium that is part of a serous pericardium. http://purl.obolibrary.org/obo/UBERON_0007195 stroma of bone marrow http://purl.obolibrary.org/obo/UBERON_0003891 stroma The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis. http://purl.obolibrary.org/obo/UBERON_0007196 tracheobronchial tree http://purl.obolibrary.org/obo/UBERON_0000062 organ The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells. http://purl.obolibrary.org/obo/UBERON_0007204 brachiocephalic vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The vasculature consisting of brachiocephalic arteries and veins. http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that develops_from a cranial neural crest. http://purl.obolibrary.org/obo/UBERON_0007214 mesenchyme derived from trunk neural crest http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme Mesenchyme that develops_from a trunk neural crest. http://purl.obolibrary.org/obo/UBERON_0007239 tunica media of artery http://purl.obolibrary.org/obo/UBERON_0002522 tunica media A tunica media that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0007240 tunica adventitia of artery http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel A tunica adventitia that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0007241 tunica adventitia of vein http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel A tunica adventitia that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0007242 tunica intima of vein http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer A tunica intima that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0007243 tunica media of vein http://purl.obolibrary.org/obo/UBERON_0002522 tunica media A tunica media that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis http://purl.obolibrary.org/obo/UBERON_0002020 gray matter Gray matter of the central nervous system which is a collection of clustered nuclei. http://purl.obolibrary.org/obo/UBERON_0007247 nucleus of superior olivary complex http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei. http://purl.obolibrary.org/obo/UBERON_0007267 trachea pre-cartilage rings http://purl.obolibrary.org/obo/UBERON_0009505 mesenchyme of trachea A pre-cartilage condensation that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0007269 pectoral appendage musculature http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex Any collection of muscles that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007271 appendage musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of an appendage. http://purl.obolibrary.org/obo/UBERON_0007272 pectoral appendage skeleton http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0007277 presumptive hindbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. http://purl.obolibrary.org/obo/UBERON_0007278 presumptive sinus venosus http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is part of the heart tube and will become the sinus venosus. http://purl.obolibrary.org/obo/UBERON_0007280 presumptive endocardium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a endocardium. http://purl.obolibrary.org/obo/UBERON_0007281 presumptive midbrain hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that gives rise to the midbrain hindbrain boundary. http://purl.obolibrary.org/obo/UBERON_0007282 presumptive segmental plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0007284 presumptive neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A presumptive structure that has the potential to develop into a neural plate. http://purl.obolibrary.org/obo/UBERON_0007285 presumptive paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The part of the blastula that has the potential to develop into a paraxial mesoderm. http://purl.obolibrary.org/obo/UBERON_0007300 pectoral appendage blood vessel http://purl.obolibrary.org/obo/UBERON_0007301 appendage blood vessel A blood vessel that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007301 appendage blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0007302 pectoral appendage vasculature http://purl.obolibrary.org/obo/UBERON_0007304 appendage vasculature A vasculature that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007303 pharyngeal vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a chordate pharynx. http://purl.obolibrary.org/obo/UBERON_0007304 appendage vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0007324 pancreatic lobule http://purl.obolibrary.org/obo/UBERON_0000064 organ part A dense accumulation of exocrine glands in the pancreas often surrounding islets of Langerhans. http://purl.obolibrary.org/obo/UBERON_0007375 roof of mouth http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure A multi-tissue structure consisting of bone and soft tissue that forms a part of the roof of the oral cavity. In mammals this is the combination of the primary palate (premaxilla) and the secondary palate. In early tetrapods it consists of the vomer, pterygoid, parasphenoid, palatine and ectopterygoid bones. http://purl.obolibrary.org/obo/UBERON_0007376 outer epithelium http://purl.obolibrary.org/obo/UBERON_0003102 surface structure The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. http://purl.obolibrary.org/obo/UBERON_0007383 enveloping layer of ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Outermost layer of cells surrounding the embryo. http://purl.obolibrary.org/obo/UBERON_0007389 paired limb/fin cartilage http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue A cartilage tissue that is part of a paired limb or fin. http://purl.obolibrary.org/obo/UBERON_0007390 pectoral appendage cartilage tissue http://purl.obolibrary.org/obo/UBERON_0007389 paired limb/fin cartilage A cartilage tissue that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007414 nucleus of midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A nucleus of brain that spans a midbrain tegmentum. http://purl.obolibrary.org/obo/UBERON_0007473 lumen of epithelial sac http://purl.obolibrary.org/obo/UBERON_0012467 enclosed anatomical space The space within an epithelial sphere. http://purl.obolibrary.org/obo/UBERON_0007475 matrix-based tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified. http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac http://purl.obolibrary.org/obo/UBERON_0009856 sac An epithelial tube that is open at one end only. http://purl.obolibrary.org/obo/UBERON_0007500 epithelial tube open at both ends http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube An epithelial tube open at both ends that allows fluid flow. http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A closed epithelium with a lumen. http://purl.obolibrary.org/obo/UBERON_0007521 smooth muscle sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A ring of smooth muscle cells whose contraction closes the opening of the ring. http://purl.obolibrary.org/obo/UBERON_0007522 striated muscle sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A ring of striated muscle cells whose contraction closes the opening of the ring. http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme with little extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchymal cells that are migrating. http://purl.obolibrary.org/obo/UBERON_0007592 ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA]. http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium bearing vibratile cilia on the free surface. http://purl.obolibrary.org/obo/UBERON_0007617 synovial cavity of joint http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical cavity that surrounded_by a synovial joint. http://purl.obolibrary.org/obo/UBERON_0007625 pigment epithelium of eye http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium Epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules. http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus A neural nucleus that is part of a medulla oblongata. http://purl.obolibrary.org/obo/UBERON_0007641 trigeminal nuclear complex http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]. http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that connects two structures. http://purl.obolibrary.org/obo/UBERON_0007652 esophageal sphincter http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle A sphincter that is part of an esophagus. http://purl.obolibrary.org/obo/UBERON_0007688 anlage http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. http://purl.obolibrary.org/obo/UBERON_0007719 bone of reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A bone that is part of a reproductive organ. http://purl.obolibrary.org/obo/UBERON_0007771 epidermis gland http://purl.obolibrary.org/obo/UBERON_0002419 skin gland A gland that is part of a epidermis. http://purl.obolibrary.org/obo/UBERON_0007779 transudate http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces. http://purl.obolibrary.org/obo/UBERON_0007794 secretion of serous gland http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Any fluid produced by a serous gland. http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region http://purl.obolibrary.org/obo/UBERON_0003567 abdomen connective tissue Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots. http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. http://purl.obolibrary.org/obo/UBERON_0007812 post-anal tail http://purl.obolibrary.org/obo/UBERON_0002415 tail A tail that extends from the posterior tip of the organism to the anus, contains muscle and skeleton. http://purl.obolibrary.org/obo/UBERON_0007823 appendage girdle region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0007828 girdle bone/zone http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a appendage girdle region. http://purl.obolibrary.org/obo/UBERON_0007829 pectoral girdle bone http://purl.obolibrary.org/obo/UBERON_0010741 bone of pectoral complex A bone that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/UBERON_0007842 membrane bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Bone element that arises as a result of intramembranous ossification. http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of cartilage tissue and may be permanent or transient. http://purl.obolibrary.org/obo/UBERON_0007845 regular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue. http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts). http://purl.obolibrary.org/obo/UBERON_0007914 bone of craniocervical region http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0008001 irregular bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid. http://purl.obolibrary.org/obo/UBERON_0008114 joint of girdle http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint A skeletal joint that is part of a appendage girdle region. http://purl.obolibrary.org/obo/UBERON_0008115 surface of cartilage http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical surface that is part of a cartilage element. http://purl.obolibrary.org/obo/UBERON_0008193 pneumatized bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]. http://purl.obolibrary.org/obo/UBERON_0008196 muscle of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle Any muscle organ that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Musculature system of the pharyngeal and head regions. http://purl.obolibrary.org/obo/UBERON_0008231 dorsal thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax. http://purl.obolibrary.org/obo/UBERON_0008243 upper back muscle http://purl.obolibrary.org/obo/UBERON_0003830 thoracic segment muscle A muscle of back that is part of a dorsal thoracic segment of trunk. http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of a heart [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0008342 intestinal villus of duodenum http://purl.obolibrary.org/obo/UBERON_0001213 intestinal villus An intestinal villus in the duodenum. http://purl.obolibrary.org/obo/UBERON_0008346 duodenal epithelium http://purl.obolibrary.org/obo/UBERON_0013636 epithelium of intestinal villus An epithelium that is part of a duodenum. http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium Epithelium pertaining to the trachea and bronchi. http://purl.obolibrary.org/obo/UBERON_0008429 cervical vertebral foramen http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen A vertebral foramen that is part of a cervical vertebra. http://purl.obolibrary.org/obo/UBERON_0008432 thoracic vertebral foramen http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen A vertebral foramen that is part of a thoracic vertebra. http://purl.obolibrary.org/obo/UBERON_0008780 inner cell mass derived epiblast http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers. http://purl.obolibrary.org/obo/UBERON_0008814 pharyngeal arch system http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0008816 embryonic head http://purl.obolibrary.org/obo/UBERON_0000033 head A head that is part of a embryo. http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organ A brain that develops_from a neural tube. http://purl.obolibrary.org/obo/UBERON_0008835 hepatic diverticulum http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. http://purl.obolibrary.org/obo/UBERON_0008851 ectoplacental cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals. http://purl.obolibrary.org/obo/UBERON_0008856 stomach muscularis externa http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue The smooth muscle layer of the stomach wall that functions to churn and mix food and gastric secretions as well as to move food along the digestive tract to the intestines. http://purl.obolibrary.org/obo/UBERON_0008858 pyloric canal http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter. http://purl.obolibrary.org/obo/UBERON_0008861 pyloric gastric gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]. http://purl.obolibrary.org/obo/UBERON_0008876 hypodermis skeletal muscle layer http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any skeletal muscle organ in the hypodermis / superficial fascia. http://purl.obolibrary.org/obo/UBERON_0008886 pulmonary vascular system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins. http://purl.obolibrary.org/obo/UBERON_0008895 splanchnocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Subdivision of endoskeleton derived from pharyngeal arches. http://purl.obolibrary.org/obo/UBERON_0008907 dermal bone http://purl.obolibrary.org/obo/UBERON_0007842 membrane bone Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]. http://purl.obolibrary.org/obo/UBERON_0008909 perichordal bone http://purl.obolibrary.org/obo/UBERON_0012075 replacement bone Bone element that is adjacent to the notochord. http://purl.obolibrary.org/obo/UBERON_0008946 lung parenchyma http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma A parenchyma that is part of a lung. http://purl.obolibrary.org/obo/UBERON_0008951 left lung lobe http://purl.obolibrary.org/obo/UBERON_0000101 lobe of lung A lobe of lung that is part of a left lung. http://purl.obolibrary.org/obo/UBERON_0008989 submucosal esophageal gland http://purl.obolibrary.org/obo/UBERON_0011148 submucosal gland One of the racemose glands in the walls of the esophagus that in humans are small and serve principally to lubricate the food but in some birds secrete a milky fluid on which the young are fed. http://purl.obolibrary.org/obo/UBERON_0008998 vasculature of brain http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system System pertaining to blood vessels in the brain. http://purl.obolibrary.org/obo/UBERON_0009015 upper back skin http://purl.obolibrary.org/obo/UBERON_0001418 skin of thorax A zone of skin that is part of a dorsal thoracic segment of trunk. http://purl.obolibrary.org/obo/UBERON_0009030 left pulmonary vein http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein Vein that drains left lung and returns blood to the heart. http://purl.obolibrary.org/obo/UBERON_0009032 right pulmonary vein http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein Vein that drains right lung and returns blood to the heart. http://purl.obolibrary.org/obo/UBERON_0009117 indifferent gonad http://purl.obolibrary.org/obo/UBERON_0000991 gonad A gonad prior to differentiating into a definitive testis or ovary. http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglion http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Cranial ganglion which develops from an epibranchial placode. http://purl.obolibrary.org/obo/UBERON_0009129 right atrium endocardium http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium Endocardium that is part of the right atrium. http://purl.obolibrary.org/obo/UBERON_0009133 pleuroperitoneal membrane http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities. http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein A vein that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0009142 entire embryonic mesenchyme http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Sum total of mesenchyme in the embryo. http://purl.obolibrary.org/obo/UBERON_0009191 sphenoid bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element A sphenoid endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0009193 sphenoid cartilage element http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element A sphenoid endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0009204 medial nasal process mesenchyme http://purl.obolibrary.org/obo/UBERON_0009501 mesenchyme of fronto-nasal process Mesenchyme that is part of a medial nasal prominence. http://purl.obolibrary.org/obo/UBERON_0009479 ectoderm of buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a buccopharyngeal membrane. http://purl.obolibrary.org/obo/UBERON_0009480 endoderm of buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a buccopharyngeal membrane. http://purl.obolibrary.org/obo/UBERON_0009482 associated mesenchyme of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue A portion of mesenchymal tissue associated with an individual pharyngeal arch. http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0009501 mesenchyme of fronto-nasal process http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the frontonasal region of the head. http://purl.obolibrary.org/obo/UBERON_0009503 mesenchyme of hindgut http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing hindgut. http://purl.obolibrary.org/obo/UBERON_0009505 mesenchyme of trachea http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that is part of a developing trachea. http://purl.obolibrary.org/obo/UBERON_0009521 anal membrane endodermal component http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An endoderm that is part of a anal region. http://purl.obolibrary.org/obo/UBERON_0009526 maxillary process mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a maxillary prominence. http://purl.obolibrary.org/obo/UBERON_0009548 hepatic sinusoid of left of lobe of liver http://purl.obolibrary.org/obo/UBERON_0001281 hepatic sinusoid A hepatic sinusoid that is part of a left lobe of liver. http://purl.obolibrary.org/obo/UBERON_0009549 hepatic sinusoid of right of lobe of liver http://purl.obolibrary.org/obo/UBERON_0001281 hepatic sinusoid A hepatic sinusoid that is part of a right lobe of liver. http://purl.obolibrary.org/obo/UBERON_0009550 endoderm of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0009566 intestinal submucosa http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract A submucosa that is part of a intestine. http://purl.obolibrary.org/obo/UBERON_0009568 trunk region of vertebral column http://purl.obolibrary.org/obo/UBERON_0006077 subdivision of vertebral column Subdivision of vertebral column that corresponds to the trunk of the body, containing the trunk/presacral vertebrae. In organisms that have a thoracic and lumbar distinction, this corresponds to the sum of both of these regions. http://purl.obolibrary.org/obo/UBERON_0009570 spinal cord sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future spinal cord. http://purl.obolibrary.org/obo/UBERON_0009576 medulla oblongata sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future medulla oblongata. http://purl.obolibrary.org/obo/UBERON_0009577 metencephalon sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future metencephalon. http://purl.obolibrary.org/obo/UBERON_0009578 myelencephalon sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future myelencephalon. http://purl.obolibrary.org/obo/UBERON_0009584 1st arch mandibular mesenchyme http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme Mesenchyme that is part of a 1st arch mandibular component. http://purl.obolibrary.org/obo/UBERON_0009602 left lung associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme Mesenchyme that is part of a developing left lung. http://purl.obolibrary.org/obo/UBERON_0009603 right lung associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme Mesenchyme that is part of a developing right lung. http://purl.obolibrary.org/obo/UBERON_0009611 midbrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a presumptive midbrain. http://purl.obolibrary.org/obo/UBERON_0009614 hindbrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a presumptive hindbrain. http://purl.obolibrary.org/obo/UBERON_0009616 presumptive midbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a midbrain. http://purl.obolibrary.org/obo/UBERON_0009617 head paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles. http://purl.obolibrary.org/obo/UBERON_0009621 tail somite http://purl.obolibrary.org/obo/UBERON_0002329 somite A somite that is part of a tail. http://purl.obolibrary.org/obo/UBERON_0009652 bronchus basement membrane http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane A basement membrane that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0009653 trachea basement membrane http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane A basement membrane that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0009661 midbrain nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus located in the midbrain. http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus located within the hindbrain. http://purl.obolibrary.org/obo/UBERON_0009669 embryonic cloacal lumen http://purl.obolibrary.org/obo/UBERON_0012463 cloacal lumen An anatomical space that surrounded_by a embryonic cloaca. http://purl.obolibrary.org/obo/UBERON_0009670 rectal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a rectum. http://purl.obolibrary.org/obo/UBERON_0009712 endocardium of right ventricle http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle Any endocardium that is part of the right ventricle of the heart. http://purl.obolibrary.org/obo/UBERON_0009713 endocardium of left ventricle http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle Any endocardium that is part of the left ventricle of the heart. http://purl.obolibrary.org/obo/UBERON_0009715 stomodeal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a stomodeum. http://purl.obolibrary.org/obo/UBERON_0009751 cardiac mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures. http://purl.obolibrary.org/obo/UBERON_0009752 pancreas mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing pancreas. http://purl.obolibrary.org/obo/UBERON_0009758 abdominal ganglion http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglion A ganglion that is part of a abdominal segment of trunk. http://purl.obolibrary.org/obo/UBERON_0009778 pleural sac http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A serous sac that has the pleura and the pleural cavity as parts. http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form. http://purl.obolibrary.org/obo/UBERON_0009846 embryonic cloacal epithelium http://purl.obolibrary.org/obo/UBERON_0012481 cloacal epithelium An epithelium that is part of a embryonic cloaca. http://purl.obolibrary.org/obo/UBERON_0009850 nematode larva http://purl.obolibrary.org/obo/UBERON_0002548 larva A multicellular organism that existence_starts_and_ends_during a nematode larval stage. http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0009856 sac Branch or outpocketing of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland. http://purl.obolibrary.org/obo/UBERON_0009889 secondary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract). http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a developing face. http://purl.obolibrary.org/obo/UBERON_0009912 anatomical lobe http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A portion of an organ, such as the liver, lung, breast, or brain. http://purl.obolibrary.org/obo/UBERON_0009953 post-embryonic organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism A multicellular organism that existence_starts_with a post-embryonic stage. http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode http://purl.obolibrary.org/obo/UBERON_0002546 cranial placode Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia. http://purl.obolibrary.org/obo/UBERON_0009970 epithelium of pancreatic duct http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelium that is part of a pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has more than one cell as a part. http://purl.obolibrary.org/obo/UBERON_0010009 aggregate regional part of brain http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]. http://purl.obolibrary.org/obo/UBERON_0010031 6th arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 6. http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element An organ of the digestive tract that is capable of retaining and storing food. http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 1. http://purl.obolibrary.org/obo/UBERON_0010045 1st arch maxillary mesenchyme http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme Mesenchyme that is part of a 1st arch maxillary component. http://purl.obolibrary.org/obo/UBERON_0010046 entire pharyngeal arch associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells. http://purl.obolibrary.org/obo/UBERON_0010047 oral gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract Gland of the epithelium lining the oral cavity. The most common are the salivary glands. http://purl.obolibrary.org/obo/UBERON_0010077 cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium consisting of cuboidal epithelial cells. http://purl.obolibrary.org/obo/UBERON_0010081 future common hepatic duct http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system An extrahepatic bile duct that has the potential to develop into a common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0010083 future dermis http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that has the potential to develop into a dermis. http://purl.obolibrary.org/obo/UBERON_0010084 future diaphragm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A structure that will develop into a diaphragm. http://purl.obolibrary.org/obo/UBERON_0010092 future metencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a metencephalon. http://purl.obolibrary.org/obo/UBERON_0010096 future myelencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a myelencephalon. http://purl.obolibrary.org/obo/UBERON_0010125 future superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002020 gray matter A gray matter that has the potential to develop into a superior salivatory nucleus. http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers. http://purl.obolibrary.org/obo/UBERON_0010136 epithelial sheet http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet is a flat surface consisting of closely packed epithelial cells. http://purl.obolibrary.org/obo/UBERON_0010152 skin mucus http://purl.obolibrary.org/obo/UBERON_0000912 mucus A mucous secretion that is produced by glands in the epidermis. http://purl.obolibrary.org/obo/UBERON_0010161 lumen of blood vessel http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a blood vessel. http://purl.obolibrary.org/obo/UBERON_0010162 post-anal tail tip http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The distal end of the tail. http://purl.obolibrary.org/obo/UBERON_0010183 liver trabecula http://purl.obolibrary.org/obo/UBERON_0000440 trabecula A trabecula that is part of a liver. http://purl.obolibrary.org/obo/UBERON_0010188 protuberance http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A roughly circular bulge in a surface. http://purl.obolibrary.org/obo/UBERON_0010190 pair of dorsal aortae http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation. http://purl.obolibrary.org/obo/UBERON_0010192 genital artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery One of the laterally paired arteries that supply the gonads. http://purl.obolibrary.org/obo/UBERON_0010194 hepatic portal system http://purl.obolibrary.org/obo/UBERON_0005806 portal system A portal system that begins in capillaries in the wall of the digestive tract and and runs as the hepatic portal vein to the liver. http://purl.obolibrary.org/obo/UBERON_0010199 bona-fide anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity An anatomical boundary that corresponds to some physical discontinuity. http://purl.obolibrary.org/obo/UBERON_0010204 tail vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a post-anal tail. http://purl.obolibrary.org/obo/UBERON_0010227 future cardiac atrium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Multi-tissue structure that is part of the heart tube and will become the cardiac atrium. http://purl.obolibrary.org/obo/UBERON_0010230 eyeball of camera-type eye http://purl.obolibrary.org/obo/UBERON_0000020 sense organ The core globe-shaped component of the camera-type eye. http://purl.obolibrary.org/obo/UBERON_0010243 merocrine gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged. http://purl.obolibrary.org/obo/UBERON_0010252 1st arch mandibular mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010253 1st arch maxillary mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch maxillary mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010256 4th arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010257 6th arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Mesenchyme that develops_from a rhombencephalon neural crest. http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010276 space in vertebral column http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Any anatomical space that is part of a vertebral column. http://purl.obolibrary.org/obo/UBERON_0010285 midbrain basal plate http://purl.obolibrary.org/obo/UBERON_0002020 gray matter Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. http://purl.obolibrary.org/obo/UBERON_0010286 midbrain neural tube http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of neural tube that gives rise to the midbrain. http://purl.obolibrary.org/obo/UBERON_0010294 scleral endothelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An endothelium that is part of a sclera. http://purl.obolibrary.org/obo/UBERON_0010295 substantia propria of sclera http://purl.obolibrary.org/obo/UBERON_0010291 layer of sclera A stroma that is part of a sclera. http://purl.obolibrary.org/obo/UBERON_0010299 scleral mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme surrounding the developing optic cup which develops into the sclera. http://purl.obolibrary.org/obo/UBERON_0010303 extraembryonic epithelium http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue An epithelium that is part of a extraembryonic structure. http://purl.obolibrary.org/obo/UBERON_0010304 non-keratinized stratified squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006915 stratified squamous epithelium Stratified squamous epithelium is a stratified squamous epithelium, the cells of which synthesizes but does not accumulate keratin. Examples: epithelium of vagina, epithelium of wall of esophagus. http://purl.obolibrary.org/obo/UBERON_0010312 immature eye http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Developing anatomical structure that develops into the eyeball and associated structures. http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An anatomical structure that develops from the neural crest. http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has some part that develops from the neural crest. http://purl.obolibrary.org/obo/UBERON_0010321 skeletal element of eye region http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A skeletal element that is part of a orbital region. http://purl.obolibrary.org/obo/UBERON_0010323 cranial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure Mesenchyme that is part of a limb/fin bud. http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Mesenchyme that is part of a extraembryonic membrane. http://purl.obolibrary.org/obo/UBERON_0010334 maxillary process mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest Mesenchyme that develops_from a neural crest and is part of a maxillary process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010335 maxillary process mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0009526 maxillary process mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a maxillary process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010336 mandibular process mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010337 mandibular process mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0006905 mandibular process mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010338 1st arch maxillary mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch maxillary mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010339 1st arch mandibular mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010345 4th arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010347 6th arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010362 endoskeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues. http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification. http://purl.obolibrary.org/obo/UBERON_0010364 dermal skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements. http://purl.obolibrary.org/obo/UBERON_0010368 pulmonary lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa. http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Epithelium composed of cells that develops from the ectoderm[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a somatopleure. http://purl.obolibrary.org/obo/UBERON_0010378 mesenchyme from splanchnopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a splanchnopleure. http://purl.obolibrary.org/obo/UBERON_0010399 spleen trabecular artery http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel One of the branches of the splenic artery[MP]. http://purl.obolibrary.org/obo/UBERON_0010400 spleen trabecular vein http://purl.obolibrary.org/obo/UBERON_0013126 vein of abdomen One of the veins that feed the splenic vein. http://purl.obolibrary.org/obo/UBERON_0010409 ocular surface region http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms. http://purl.obolibrary.org/obo/UBERON_0010427 ciliary processes http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens. http://purl.obolibrary.org/obo/UBERON_0010428 flat bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow. http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels. http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile. http://purl.obolibrary.org/obo/UBERON_0010521 electroreceptor organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ An organ that is capable of detecting electrical stimulus. http://purl.obolibrary.org/obo/UBERON_0010522 replacement element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that forms as a replacement or substitution of another element or tissue. http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. http://purl.obolibrary.org/obo/UBERON_0010527 cavity of bone organ http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity An organ cavity that surrounded_by a bone. http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0010708 pectoral complex http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The subdivision of the skeleton of either the pectoral or pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle). http://purl.obolibrary.org/obo/UBERON_0010741 bone of pectoral complex http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin. http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A muscle of a pectoral girdle, pectoral fin or anterior limb. http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any muscle organ that is part of either the head or the neck. http://purl.obolibrary.org/obo/UBERON_0011004 pharyngeal arch cartilage http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage A cartilage element that is part of a splanchnocranium. http://purl.obolibrary.org/obo/UBERON_0011085 palatoquadrate arch http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The dorsal portion of the first pharyngeal arch, comprising the upper jaw[ZFIN,VHOG]. http://purl.obolibrary.org/obo/UBERON_0011094 vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011095 vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The pre-cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011108 synovial joint of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0008114 joint of girdle A synovial joint that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. http://purl.obolibrary.org/obo/UBERON_0011137 axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011138 postcranial axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011148 submucosal gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland Gland of the lamina epithelialis mucosae which perforate the lamina muscularis, with their adenomeres located in the submucosal connective tissue. http://purl.obolibrary.org/obo/UBERON_0011156 facial skeleton http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull Subdivision of skull that consists of the facial bones. http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The skull can be divided into two: the neurocranium and the facial skeleton. http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone http://purl.obolibrary.org/obo/UBERON_0004766 cranial bone A bone that is part of a neurocranium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0011171 joint connecting upper and lower jaws http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint Synovial joint that articulates bones of upper and lower jaw. http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium An epithelium that is part of a crypt of Lieberkuhn. http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A sphincter muscle that is part of the gastrointestinal system. http://purl.obolibrary.org/obo/UBERON_0011189 lamina propria of large intestine http://purl.obolibrary.org/obo/UBERON_0004780 gastrointestinal system lamina propria A lamina propria that is part of a large intestine. http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine http://purl.obolibrary.org/obo/UBERON_0012367 muscle layer of intestine A muscle layer that is part of a large intestine. http://purl.obolibrary.org/obo/UBERON_0011201 muscle layer of small intestine http://purl.obolibrary.org/obo/UBERON_0012367 muscle layer of intestine A muscle layer that is part of a small intestine. http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A multi cell part structure that is part of a central nervous system. http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A subdivision of an anatomical system. http://purl.obolibrary.org/obo/UBERON_0011233 synovial membrane of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa. http://purl.obolibrary.org/obo/UBERON_0011241 ethmoid region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The most anterior region of the braincase. Provides structural support for peripheral olfactory organ. http://purl.obolibrary.org/obo/UBERON_0011249 appendicular skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011270 dorsal trunk http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The part of the trunk that is in the dorsum[cjm]. http://purl.obolibrary.org/obo/UBERON_0011362 cranial blood vasculature http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature A blood vasculature that is part of a head. http://purl.obolibrary.org/obo/UBERON_0011566 lumen of esophagus http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a esophagus. http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in an individual limb or fin. http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). http://purl.obolibrary.org/obo/UBERON_0011595 jaw region http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions. http://purl.obolibrary.org/obo/UBERON_0011597 bone of upper jaw http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw Any bone that is part of the upper jaw skeleton. This includes (when present): the maxilla, the quadrate (in some species). http://purl.obolibrary.org/obo/UBERON_0011642 oral epithelium from ectoderm http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium An epithelium that develops_from a ectoderm and is part of a oral epithelium. http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011677 trunk vertebra http://purl.obolibrary.org/obo/UBERON_0004451 trunk or cervical vertebra A vertebra in the trunk region. For tetrapods, includes lumbar and thoracic vertebrae. Excludes caudal/coccygeal vertebra, which are located posteriorly. In tetrapods this includes thoracic, lumbar and sacral vertebrae, and excludes the cervical vertebrae, which are located anteriorly. http://purl.obolibrary.org/obo/UBERON_0011695 embryonic cardiovascular system http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system A cardiovascular system that is part of a conceptus. http://purl.obolibrary.org/obo/UBERON_0011772 lower jaw opening http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a bone of lower jaw. http://purl.obolibrary.org/obo/UBERON_0011773 upper jaw opening http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a bone of upper jaw. http://purl.obolibrary.org/obo/UBERON_0011777 nucleus of spinal cord http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A neural nucleus that is part of the spinal cord. http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a head. http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that does not develop into a component of the nervous system. http://purl.obolibrary.org/obo/UBERON_0011820 atrioventricular region http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart. http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets. http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus An acinus that is part of a exocrine gland. http://purl.obolibrary.org/obo/UBERON_0011861 aorta collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011862 pulmonary collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011863 bone collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011864 tendon collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011865 corneal stroma collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011878 muscle layer of esophagus http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract A muscle layer that is part of a wall of esophagus. http://purl.obolibrary.org/obo/UBERON_0011892 anterior uvea http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris. http://purl.obolibrary.org/obo/UBERON_0011899 epimysium http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. http://purl.obolibrary.org/obo/UBERON_0011919 yolk sac blood island http://purl.obolibrary.org/obo/UBERON_0003061 blood island Masses of developing blood cells attached to endothelium in the yolk sac. http://purl.obolibrary.org/obo/UBERON_0011953 stomach glandular region http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach A region of the stomach that is lined with glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0011955 left hepatic vein http://purl.obolibrary.org/obo/UBERON_0001143 hepatic vein A hepatic vein that is part of a left lobe of liver. http://purl.obolibrary.org/obo/UBERON_0011956 right hepatic vein http://purl.obolibrary.org/obo/UBERON_0001143 hepatic vein A hepatic vein that is part of a right lobe of liver. http://purl.obolibrary.org/obo/UBERON_0011997 coelom http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The aggregate of the coelemic cavity lumen plus the membranes that line the lumen. http://purl.obolibrary.org/obo/UBERON_0012054 myocoele http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity within a myotome. http://purl.obolibrary.org/obo/UBERON_0012071 palate bone http://purl.obolibrary.org/obo/UBERON_0008907 dermal bone Any bone that is part of a palate. http://purl.obolibrary.org/obo/UBERON_0012075 replacement bone http://purl.obolibrary.org/obo/UBERON_0010522 replacement element Bone that forms as a replacement of another structural tissue. http://purl.obolibrary.org/obo/UBERON_0012082 bronchial lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0012172 stomach primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium A primordium that has the potential to develop into a stomach. http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0012193 phrenic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins. http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that originates from the abdominal aorta. http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified]. http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Epithelium that derives from the mesoderm. [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure One of five swellings formed during the development of the face. http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery http://purl.obolibrary.org/obo/UBERON_0003502 neck blood vessel An artery of the neck. http://purl.obolibrary.org/obo/UBERON_0012321 deep cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery The deep cervical artery (Profunda cervicalis) is an artery of the neck. http://purl.obolibrary.org/obo/UBERON_0012324 transverse cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery The transverse cervical artery (transverse artery of neck, transversa colli artery) is a branch of the thyrocervical trunk, running at a higher level than the suprascapular artery. http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A bone element that is part of a jaw region. http://purl.obolibrary.org/obo/UBERON_0012367 muscle layer of intestine http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract A muscle layer that is part of an intestine. http://purl.obolibrary.org/obo/UBERON_0012375 subserosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of tissue between the muscularis and serosa. http://purl.obolibrary.org/obo/UBERON_0012418 respiratory system venous smooth muscle http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle A smooth muscle tissue that is part of a respiratory system venous blood vessel. http://purl.obolibrary.org/obo/UBERON_0012423 layer of microvilli http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A layer of microvilli, Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0012425 striated border microvillus layer http://purl.obolibrary.org/obo/UBERON_0012423 layer of microvilli A microvillus layer that is striated and found in the intestine. http://purl.obolibrary.org/obo/UBERON_0012429 hematopoietic tissue http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue Blood-forming tissue, consisting of reticular fibers and cells. http://purl.obolibrary.org/obo/UBERON_0012430 tunica fibrosa of eyeball http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth. http://purl.obolibrary.org/obo/UBERON_0012463 cloacal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a cloaca. http://purl.obolibrary.org/obo/UBERON_0012464 cloacal vent http://purl.obolibrary.org/obo/UBERON_0000161 orifice The opening of the cloacal chamber to the outside of the organism. Birds maintain a single cloacal opening throughout their lives. http://purl.obolibrary.org/obo/UBERON_0012465 lumen of terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a terminal part of digestive tract. http://purl.obolibrary.org/obo/UBERON_0012467 enclosed anatomical space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space with no opening to another space or to the exterior. http://purl.obolibrary.org/obo/UBERON_0012475 skeleton of pectoral complex http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0012477 dorsal part of neck http://purl.obolibrary.org/obo/UBERON_0005434 cervical region The posterior region of the neck, including the suboccipital region. http://purl.obolibrary.org/obo/UBERON_0012478 cloacal gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0012480 cloacal mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a cloaca [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012481 cloacal epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0012482 submucosa of cloaca http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract A submucosa that is part of a cloaca [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012483 serosa of cloaca http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a cloaca [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012486 muscle layer of cloaca http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract A muscular coat that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0012488 muscle layer of duodenum http://purl.obolibrary.org/obo/UBERON_0011201 muscle layer of small intestine A muscular coat that is part of a duodenum. http://purl.obolibrary.org/obo/UBERON_0012489 muscle layer of colon http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine A muscular coat that is part of a colon. http://purl.obolibrary.org/obo/UBERON_0012490 muscle layer of anal canal http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine A muscular coat that is part of a anal canal. http://purl.obolibrary.org/obo/UBERON_0012504 adventitia of esophagus http://purl.obolibrary.org/obo/UBERON_0005742 adventitia An adventitia that is part of a esophagus. http://purl.obolibrary.org/obo/UBERON_0012650 gastroduodenal junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction An anatomical junction that connects a stomach and connects a duodenum. http://purl.obolibrary.org/obo/UBERON_0012651 mucosa of gastroduodenal junction http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a gastroduodenal junction. http://purl.obolibrary.org/obo/UBERON_0013126 vein of abdomen http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel A vein that is part of a abdomen. http://purl.obolibrary.org/obo/UBERON_0013127 pulmonary venous system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the venous system that drains the lungs[Kardong]. http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains a lip. http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Any vein within the general circulation that transports blood back to the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0013158 foregut-midgut junction gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0013212 anal sac gland secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A bodily secretion that is produced by a gland of anal sac. http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0013411 cranial cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity that is the lumen of the skull and contains the brain. http://purl.obolibrary.org/obo/UBERON_0013479 lung endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium A blood vessel endothelium that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0013482 crypt of Lieberkuhn of duodenum http://purl.obolibrary.org/obo/UBERON_0001241 crypt of Lieberkuhn of small intestine An intestinal crypt that is located in the duodenum. http://purl.obolibrary.org/obo/UBERON_0013485 crypt of Lieberkuhn of colon http://purl.obolibrary.org/obo/UBERON_0001984 crypt of Lieberkuhn of large intestine An intestinal crypt that is located in the colon. The colonic crypts of Lieberkühn are straight and unbranched and lined largely with goblet cells. http://purl.obolibrary.org/obo/UBERON_0013501 cloacal sphincter http://purl.obolibrary.org/obo/UBERON_0014783 cloacal muscle A sphincter muscle that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0013503 caudal vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A caudal vertebra endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0013504 caudal vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0018142 caudal vertebra endochondral element A caudal vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0013505 cervical vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A cervical vertebra endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0013506 cervical vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015007 cervical vertebra endochondral element A cervical vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0013507 thoracic vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage A thoracic vertebra endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0013508 thoracic vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015008 thoracic vertebra endochondral element A thoracic vertebra endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0013514 space surrounding organism http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The space that surrounds an organism. http://purl.obolibrary.org/obo/UBERON_0013525 stomach lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The anatomical space that is enclosed by a stomach. http://purl.obolibrary.org/obo/UBERON_0013636 epithelium of intestinal villus http://purl.obolibrary.org/obo/UBERON_0001902 epithelium of small intestine An epithelium that is part of a intestinal villus. http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen Anatomical space that is an opening in a bone of the skull. http://purl.obolibrary.org/obo/UBERON_0013686 anatomical conduit space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0013694 brain endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium Vascular endothelium found in blood vessels of the blood-brain-barrier. http://purl.obolibrary.org/obo/UBERON_0013695 colon endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium Vascular endothelium found in colon blood vessels. http://purl.obolibrary.org/obo/UBERON_0013697 exocrine pancreas epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium lining the exocrine pancreas. http://purl.obolibrary.org/obo/UBERON_0013700 axial musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Musculature of the head and neck, spine, and ribs. http://purl.obolibrary.org/obo/UBERON_0013701 main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. http://purl.obolibrary.org/obo/UBERON_0013702 body proper http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The region of the organism associated with the visceral organs. http://purl.obolibrary.org/obo/UBERON_0013704 notochordal canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily. http://purl.obolibrary.org/obo/UBERON_0013727 notochordal fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Fluid contained within the notochordal canal. http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An organ component layer that is part of a integumental system. http://purl.obolibrary.org/obo/UBERON_0013755 arterial blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0013756 venous blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0013757 capillary blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a capillary. http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element http://purl.obolibrary.org/obo/UBERON_0000062 organ Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart. http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Mesenchyme that develops_from the neural crest[Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0014398 respiratory muscle http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle Muscle that is part of the respiratory system. http://purl.obolibrary.org/obo/UBERON_0014399 sinusoidal space http://purl.obolibrary.org/obo/UBERON_0010161 lumen of blood vessel An anatomical space that is enclosed by a sinusoid. http://purl.obolibrary.org/obo/UBERON_0014400 hepatic sinusoidal space http://purl.obolibrary.org/obo/UBERON_0014399 sinusoidal space A sinusoidal space that is part of a hepatic sinusoid. http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A part of the body present only in a specific gender. http://purl.obolibrary.org/obo/UBERON_0014404 female anatomical structure http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure A part of the body present only in females. http://purl.obolibrary.org/obo/UBERON_0014454 visceral abdominal adipose tissue http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region Subcutaneous adipose tissue that is located in the peritoneal cavity. http://purl.obolibrary.org/obo/UBERON_0014455 subcutaneous abdominal adipose tissue http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region Subcutaneous adipose tissue that is located in the abdominal region. http://purl.obolibrary.org/obo/UBERON_0014477 thoracic skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. http://purl.obolibrary.org/obo/UBERON_0014610 thoracic spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord A ventral horn of spinal cord that is part of a thoracic spinal cord. http://purl.obolibrary.org/obo/UBERON_0014613 cervical spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord A gray matter of spinal cord that is part of a cervical spinal cord. http://purl.obolibrary.org/obo/UBERON_0014621 cervical spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord A ventral horn of spinal cord that is part of a cervical spinal cord. http://purl.obolibrary.org/obo/UBERON_0014636 thoracic spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord A gray matter of spinal cord that is part of a thoracic spinal cord. http://purl.obolibrary.org/obo/UBERON_0014702 frontonasal process epithelium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An epithelium that is part of a frontonasal prominence. http://purl.obolibrary.org/obo/UBERON_0014703 anal membrane ectodermal component http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A unilaminar epithelium that develops_from a ectoderm and is part of a anal region. http://purl.obolibrary.org/obo/UBERON_0014704 pleuroperitoneal canal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a pleuroperitoneal canal. http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory. http://purl.obolibrary.org/obo/UBERON_0014717 mucous acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The secretory unit of a mucous gland. The acinar portion is composed of mucous secreting cells. http://purl.obolibrary.org/obo/UBERON_0014719 intralobular duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is located within a lobule, with no more connective tissue intervening between ducts and secretory units (i.e., acini or tubules) than between adjacent secretory units. Intercalated and striated ducts are intralobular. http://purl.obolibrary.org/obo/UBERON_0014720 interlobar duct http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct A duct that is located between lobes, within conspicuous, thick connective tissue septa that separate lobes. All interlobar ducts are excretory. http://purl.obolibrary.org/obo/UBERON_0014776 midbrain neuromere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive midbrain. http://purl.obolibrary.org/obo/UBERON_0014777 spinal neuromere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive spinal cord. http://purl.obolibrary.org/obo/UBERON_0014783 cloacal muscle http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any muscle organ that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin. http://purl.obolibrary.org/obo/UBERON_0014794 pectoral appendage muscle http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). http://purl.obolibrary.org/obo/UBERON_0014903 primordial vasculature http://purl.obolibrary.org/obo/UBERON_0001048 primordium A portion of tissue that will develop into vasculature. http://purl.obolibrary.org/obo/UBERON_0014907 intersomitic vessel http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites. http://purl.obolibrary.org/obo/UBERON_0015007 cervical vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element A vertebral endochondral element in the cervical region of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0015008 thoracic vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element A vertebral endochondral element in the thoracic region of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0015060 sphenoid endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A sphenoid bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015129 epicardial fat http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat Visceral intrapericardial fat contiguous with the myocardial surface. http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands. http://purl.obolibrary.org/obo/UBERON_0015165 multi-unit eye http://purl.obolibrary.org/obo/UBERON_0000970 eye An eye consisting of multiple light-sensing organs. http://purl.obolibrary.org/obo/UBERON_0015178 somite border http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A region of somite adjacent to presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0015179 somite boundary epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium located in the intersomitic region. http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group An anatomical group whose component structures share a common function. http://purl.obolibrary.org/obo/UBERON_0015204 glandular system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system A non-connected functional system that is composed primarily of a gland. http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any structure that is placed on one side of the left-right axis of a bilaterian. http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. http://purl.obolibrary.org/obo/UBERON_0015280 pancreas left lobe http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A pancreatic lobule that is in_the_left_side_of a exocrine pancreas. http://purl.obolibrary.org/obo/UBERON_0015281 pancreas right lobe http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A pancreatic lobule that is in_the_right_side_of a exocrine pancreas. http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A basement membrane of epithelium that is part of a respiratory system. http://purl.obolibrary.org/obo/UBERON_0015480 proper hepatic artery http://purl.obolibrary.org/obo/UBERON_0001193 hepatic artery The hepatic artery proper (also proper hepatic artery), arises from the common hepatic artery and runs alongside the portal vein and the common bile duct to form the portal triad. The hepatic artery proper gives off a small supraduodenal artery to the duodenal bulb. Then the right gastric artery comes off and runs to the left along the lesser curvature of the stomach to meet the left gastric artery, which is a branch of the celiac trunk. It subsequently gives off the cystic artery, which feeds the gallbladder, before bifurcating into the right and left hepatic arteries. Of note, the right and left hepatic arteries may demonstrate variant anatomy. A replaced right hepatic artery may arise from the superior mesenteric artery (SMA) and a replaced left hepatic artery may arise from the left gastric artery. http://purl.obolibrary.org/obo/UBERON_0015481 left hepatic artery http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel A hepatic artery that is part of a left lobe of liver. http://purl.obolibrary.org/obo/UBERON_0015482 right hepatic artery http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel A hepatic artery that is part of a right lobe of liver. http://purl.obolibrary.org/obo/UBERON_0015485 choledocho-duodenal junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction Hat part of the duodenal wall traversed by the ductus choledochus, ductus pancreaticus, and ampulla. http://purl.obolibrary.org/obo/UBERON_0015716 anal canal epithelium http://purl.obolibrary.org/obo/UBERON_0014703 anal membrane ectodermal component An epithelium that is part of a anal canal. http://purl.obolibrary.org/obo/UBERON_0015783 smooth muscle layer in fatty layer of subcutaneous tissue http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A smooth muscle tissue that is part of a hypodermis. http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel A blood vessel that is part of a liver. http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium http://purl.obolibrary.org/obo/UBERON_0007625 pigment epithelium of eye An epithelium that is part of a camera-type eye. http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a foregut. http://purl.obolibrary.org/obo/UBERON_0015834 duodenum lamina propria http://purl.obolibrary.org/obo/UBERON_0001238 lamina propria of small intestine A lamina propria that is part of a duodenum. http://purl.obolibrary.org/obo/UBERON_0016405 pulmonary capillary http://purl.obolibrary.org/obo/UBERON_0003526 respiratory system capillary A capillary that is part of a lung. http://purl.obolibrary.org/obo/UBERON_0016458 esophageal hiatus http://purl.obolibrary.org/obo/UBERON_0000161 orifice A hole in the diaphragm through which the esophagus passes. http://purl.obolibrary.org/obo/UBERON_0016478 liver stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma A stroma that is part of a liver. http://purl.obolibrary.org/obo/UBERON_0016509 cavity of right ventricle http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the right ventricle of the heart. http://purl.obolibrary.org/obo/UBERON_0016512 lumen of duodenum http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a duodenum. http://purl.obolibrary.org/obo/UBERON_0016513 cavity of left atrium http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the left atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0016522 cavity of right atrium http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0016545 pharyngeal ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches. http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer A layer of of the central nervous system that is part of gray matter. http://purl.obolibrary.org/obo/UBERON_0016552 phlegm http://purl.obolibrary.org/obo/UBERON_0000912 mucus Mucus produced in the respiratory tract. http://purl.obolibrary.org/obo/UBERON_0016553 respiratory system mucus http://purl.obolibrary.org/obo/UBERON_0000912 mucus Any mucus produced by a mucosae of the respiratory system. This includes the mucus produced in the nasal cavity (nasal mucus) and mucus produced in the respiratory tract (phlegm). http://purl.obolibrary.org/obo/UBERON_0016566 pit http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An roughly circular indentation in a surface. http://purl.obolibrary.org/obo/UBERON_0016854 dorsal part of optic cup http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The dorsal region of the optic cup that gives rise to the dorsal part of the retina. http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the central nervous system. http://purl.obolibrary.org/obo/UBERON_0016880 future nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the nervous system. http://purl.obolibrary.org/obo/UBERON_0016885 epithelium of terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium Epithelium lining the distalmost portion of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0016886 muscle tissue of terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Any muscle tissue of the distalmost portion of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0016887 entire extraembryonic component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element A viscus that is part of a abdomen. http://purl.obolibrary.org/obo/UBERON_0018111 muscle layer of rectum http://purl.obolibrary.org/obo/UBERON_0011198 muscle layer of large intestine A muscle layer that is part of the rectum. http://purl.obolibrary.org/obo/UBERON_0018112 rectum smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0016886 muscle tissue of terminal part of digestive tract Any portion of smooth muscle tissue that is part of the rectum. http://purl.obolibrary.org/obo/UBERON_0018142 caudal vertebra endochondral element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element Any vertebra endochondral element that is part of the caudal region of the vertebral column (tail or coccyx). http://purl.obolibrary.org/obo/UBERON_0018150 skin of lower lip http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip A zone of skin that is part of a lower lip. http://purl.obolibrary.org/obo/UBERON_0018151 skin of upper lip http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip A zone of skin that is part of a upper lip. http://purl.obolibrary.org/obo/UBERON_0018234 stroma of pancreas http://purl.obolibrary.org/obo/UBERON_0003891 stroma A stroma that is part of a pancreas. http://purl.obolibrary.org/obo/UBERON_0018239 rhombomere boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A boundary delimiting a rhombomere. http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract http://purl.obolibrary.org/obo/UBERON_0000009 submucosa Any portion of submucosa that lines the digestive tract. http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Any organ component layer that consists of muscle tissue. http://purl.obolibrary.org/obo/UBERON_0018261 muscular coat of digestive tract http://purl.obolibrary.org/obo/UBERON_0006660 muscular coat A muscular coat that is part of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0018415 ethmoid foramen http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull An bone foramen in the ethmoid bone. http://purl.obolibrary.org/obo/UBERON_0018543 lumen of intestine http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The anatomical space within the intestine. http://purl.obolibrary.org/obo/UBERON_0018544 trigeminal nerve muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Muscle innervated by the trigeminal nerve (Cranial Nerve V). http://purl.obolibrary.org/obo/UBERON_0018674 heart vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart. http://purl.obolibrary.org/obo/UBERON_0019143 intramuscular adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes. http://purl.obolibrary.org/obo/UBERON_0019204 skin epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Any region of epithelium that is part of a skin region. http://purl.obolibrary.org/obo/UBERON_0019207 chorioretinal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the eye that consists of both the retina and the optic choroid. http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system http://purl.obolibrary.org/obo/UBERON_0003297 gland of integumental system An exocrine gland that is part of a integumental system. http://purl.obolibrary.org/obo/UBERON_0022293 reproductive gland secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is secreted by a reproductive gland. http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]. http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Serous membrane layer that is adjacent to and lines an organ. http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Serous membrane layer that lines to a body cavity. http://purl.obolibrary.org/obo/UBERON_0022361 lung field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the foregut into the area in which the lung will develop. http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An embryonic or larval epithelium that is committed to form part of the nervous system. http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain. http://purl.obolibrary.org/obo/UBERON_0034728 autonomic nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa. http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Any substance in the body or expelled from the body that is in a gaseous state. http://purl.obolibrary.org/obo/UBERON_0034874 air in respiratory system http://purl.obolibrary.org/obo/UBERON_0034947 gas in respiratory system Any portion of gas located in a part of the respiratory system that is composed primarily of air. http://purl.obolibrary.org/obo/UBERON_0034878 prechordal mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The area of axial mesoderm that develops into the prechordal plate. http://purl.obolibrary.org/obo/UBERON_0034903 left atrium endocardium http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium Endocardium that is part of the left atrium. http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure An multicellular anatomical structure that has subparts of multiple organs as a part. http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A cluster of cells, largely surrounded by a morphological boundary. http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity A collection of anatomical structures that are alike in terms of their morphology or developmental origin. http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. http://purl.obolibrary.org/obo/CHEBI_22728 benzopyrrole http://purl.obolibrary.org/obo/CHEBI_38180 polycyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_36078 cholanoid http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_33484 chalcogen oxoacid http://purl.obolibrary.org/obo/CHEBI_24833 oxoacid http://purl.obolibrary.org/obo/CHEBI_33721 carbohydrate acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_50320 nucleoside residue http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_51447 organic univalent group http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_51446 organic divalent group http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_20664 5beta-cholane http://purl.obolibrary.org/obo/CHEBI_35519 cholane http://purl.obolibrary.org/obo/CHEBI_27171 organic heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33672 heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_36278 cholanic acids http://purl.obolibrary.org/obo/CHEBI_36078 cholanoid http://purl.obolibrary.org/obo/CHEBI_22506 aminoglycan http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_26708 sodium atom http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion http://purl.obolibrary.org/obo/CHEBI_36914 inorganic ion http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation http://purl.obolibrary.org/obo/CHEBI_25414 monoatomic monocation http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_52211 physiological role http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_36914 inorganic ion http://purl.obolibrary.org/obo/CHEBI_24870 ion http://purl.obolibrary.org/obo/CHEBI_49637 hydrogen atom http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_24836 inorganic oxide http://purl.obolibrary.org/obo/CHEBI_25741 oxide http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_33262 elemental oxygen http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity http://purl.obolibrary.org/obo/CHEBI_24868 organic salt http://purl.obolibrary.org/obo/CHEBI_24866 salt http://purl.obolibrary.org/obo/CHEBI_35479 alkali metal salt http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_24867 monoatomic ion http://purl.obolibrary.org/obo/CHEBI_33238 monoatomic entity http://purl.obolibrary.org/obo/CHEBI_25699 organic ion http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_33504 alkali metal cation http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_25555 nitrogen atom http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_25805 oxygen atom http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_27594 carbon atom http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_37246 elemental sodium http://purl.obolibrary.org/obo/CHEBI_26712 sodium molecular entity http://purl.obolibrary.org/obo/CHEBI_38700 organic sodium salt http://purl.obolibrary.org/obo/CHEBI_24868 organic salt http://purl.obolibrary.org/obo/CHEBI_25046 linear tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_26932 tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_25585 nonmetal atom http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_26712 sodium molecular entity http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_25806 oxygen molecular entity http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_36902 chalcogen hydride http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_22314 alkali metal atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_33306 carbon group element atom http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_33582 carbon group molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound http://purl.obolibrary.org/obo/CHEBI_33655 aromatic compound http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33485 chalcogen oxoanion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion http://purl.obolibrary.org/obo/CHEBI_35519 cholane http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35722 sulfated glycosaminoglycan http://purl.obolibrary.org/obo/CHEBI_18085 glycosaminoglycan http://purl.obolibrary.org/obo/CHEBI_36238 5beta-cholanic acid http://purl.obolibrary.org/obo/CHEBI_36237 cholanic acid http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_36961 chalcocarbonic acid http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound http://purl.obolibrary.org/obo/CHEBI_50312 onium compound http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride http://purl.obolibrary.org/obo/CHEBI_35881 pnictogen hydride http://purl.obolibrary.org/obo/CHEBI_23019 carbonyl group http://purl.obolibrary.org/obo/CHEBI_51422 organodiyl group http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina http://purl.obolibrary.org/obo/UBERON_6000004 panarthropod head http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/UBERON_0005613 left dorsal aorta http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://purl.obolibrary.org/obo/UBERON_0005622 right dorsal aorta http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://purl.obolibrary.org/obo/UBERON_0035546 uveal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000034 function http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/CHEBI_33720 carbohydrate acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid http://purl.obolibrary.org/obo/CHEBI_37661 glucopyranose http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_48154 sulfur oxide http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity http://purl.obolibrary.org/obo/CHEBI_35724 carbohydrate sulfate http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative http://purl.obolibrary.org/obo/CHEBI_46883 carboxy group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group http://purl.obolibrary.org/obo/CHEBI_29793 hydridodioxygen(1+) http://purl.obolibrary.org/obo/CHEBI_33693 oxygen hydride http://purl.obolibrary.org/obo/CHEBI_13941 carbamate http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion http://purl.obolibrary.org/obo/CHEBI_43176 hydroxy group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_46629 oxo group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_33703 amino-acid cation http://purl.obolibrary.org/obo/CHEBI_25697 organic cation http://purl.obolibrary.org/obo/CHEBI_29337 azanide http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_33693 oxygen hydride http://purl.obolibrary.org/obo/CHEBI_36902 chalcogen hydride http://purl.obolibrary.org/obo/CHEBI_28976 carbonic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0000377 tracheoblast http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0000149 visual pigment cell http://purl.obolibrary.org/obo/CL_0000147 pigment cell http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000447 carbohydrate secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000306 crystallin accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000417 endopolyploid cell http://purl.obolibrary.org/obo/CL_0000412 polyploid cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell http://purl.obolibrary.org/obo/CL_0002319 neural cell http://purl.obolibrary.org/obo/UBERON_0000005 chemosensory organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ http://purl.obolibrary.org/obo/UBERON_0005726 chemosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0007037 mechanosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0035548 colic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0035398 branch of external carotid artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0005604 extrahepatic part of hepatic duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct http://purl.obolibrary.org/obo/CHEBI_23449 cyclic peptide http://purl.obolibrary.org/obo/CHEBI_16670 peptide http://purl.obolibrary.org/obo/CHEBI_38631 aminoalkylindole http://purl.obolibrary.org/obo/CHEBI_24828 indoles http://purl.obolibrary.org/obo/CHEBI_38180 polycyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_33570 benzenediols http://purl.obolibrary.org/obo/CHEBI_33853 phenols http://purl.obolibrary.org/obo/CHEBI_33791 canonical nucleoside residue http://purl.obolibrary.org/obo/CHEBI_50320 nucleoside residue http://purl.obolibrary.org/obo/CHEBI_45696 hydrogensulfate http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion http://purl.obolibrary.org/obo/CHEBI_50297 canonical nucleotide residue http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/CHEBI_33402 sulfur oxoacid http://purl.obolibrary.org/obo/CHEBI_33484 chalcogen oxoacid http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion http://purl.obolibrary.org/obo/CHEBI_33485 chalcogen oxoanion http://purl.obolibrary.org/obo/CHEBI_33424 sulfur oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_33695 information biomacromolecule http://purl.obolibrary.org/obo/CHEBI_33694 biomacromolecule http://purl.obolibrary.org/obo/CHEBI_41609 carbonate http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion http://purl.obolibrary.org/obo/CHEBI_24384 glycogens http://purl.obolibrary.org/obo/CHEBI_37163 glucan http://purl.obolibrary.org/obo/CHEBI_33263 diatomic oxygen http://purl.obolibrary.org/obo/CHEBI_33262 elemental oxygen http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_33608 hydrogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity http://purl.obolibrary.org/obo/CHEBI_37176 mononuclear parent hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_37175 organic hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation http://purl.obolibrary.org/obo/CHEBI_33703 amino-acid cation http://purl.obolibrary.org/obo/CHEBI_33700 proteinogenic amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33710 alpha-amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33792 canonical ribonucleoside residue http://purl.obolibrary.org/obo/CHEBI_33791 canonical nucleoside residue http://purl.obolibrary.org/obo/CHEBI_50299 canonical ribonucleotide residue http://purl.obolibrary.org/obo/CHEBI_50297 canonical nucleotide residue http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_1 root http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://purl.obolibrary.org/obo/NCBITaxon_862507 Mus http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_7898 Actinopterygii http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_8287 Sarcopterygii http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_88770 Panarthropoda http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_6157 Platyhelminthes http://purl.obolibrary.org/obo/NCBITaxon_1206795 Lophotrochozoa http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_8492 Archosauria http://purl.obolibrary.org/obo/NCBITaxon_1329799 Archelosauria http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_186625 Clupeocephala http://purl.obolibrary.org/obo/NCBITaxon_1489341 Osteoglossocephalai http://purl.obolibrary.org/obo/NCBITaxon_32440 Chondrostei http://purl.obolibrary.org/obo/NCBITaxon_186623 Actinopteri http://purl.obolibrary.org/obo/NCBITaxon_41665 Neopterygii http://purl.obolibrary.org/obo/NCBITaxon_186623 Actinopteri http://purl.obolibrary.org/obo/NCBITaxon_186634 Otomorpha http://purl.obolibrary.org/obo/NCBITaxon_186625 Clupeocephala http://purl.obolibrary.org/obo/NCBITaxon_186627 Cypriniphysae http://purl.obolibrary.org/obo/NCBITaxon_186626 Otophysi http://purl.obolibrary.org/obo/NCBITaxon_7952 Cypriniformes http://purl.obolibrary.org/obo/NCBITaxon_186627 Cypriniphysae http://purl.obolibrary.org/obo/NCBITaxon_32519 Ostariophysi http://purl.obolibrary.org/obo/NCBITaxon_186634 Otomorpha http://purl.obolibrary.org/obo/NCBITaxon_6960 Hexapoda http://purl.obolibrary.org/obo/NCBITaxon_197562 Pancrustacea http://purl.obolibrary.org/obo/NCBITaxon_197562 Pancrustacea http://purl.obolibrary.org/obo/NCBITaxon_197563 Mandibulata http://purl.obolibrary.org/obo/NCBITaxon_33090 Viridiplantae http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_1489341 Osteoglossocephalai http://purl.obolibrary.org/obo/NCBITaxon_32443 Teleostei http://purl.obolibrary.org/obo/NCBITaxon_186626 Otophysi http://purl.obolibrary.org/obo/NCBITaxon_32519 Ostariophysi http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_8457 Sauropsida http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_1329799 Archelosauria http://purl.obolibrary.org/obo/NCBITaxon_32561 Sauria http://purl.obolibrary.org/obo/NCBITaxon_4751 Fungi http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33392 Endopterygota http://purl.obolibrary.org/obo/NCBITaxon_33340 Neoptera http://purl.obolibrary.org/obo/NCBITaxon_7147 Diptera http://purl.obolibrary.org/obo/NCBITaxon_33392 Endopterygota http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://purl.obolibrary.org/obo/NCBITaxon_10114 Rattus http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32443 Teleostei http://purl.obolibrary.org/obo/NCBITaxon_41665 Neopterygii http://purl.obolibrary.org/obo/NCBITaxon_436489 Saurischia http://purl.obolibrary.org/obo/NCBITaxon_436486 Dinosauria http://purl.obolibrary.org/obo/NCBITaxon_436491 Theropoda http://purl.obolibrary.org/obo/NCBITaxon_436489 Saurischia http://purl.obolibrary.org/obo/NCBITaxon_436492 Coelurosauria http://purl.obolibrary.org/obo/NCBITaxon_436491 Theropoda http://purl.obolibrary.org/obo/NCBITaxon_8782 Aves http://purl.obolibrary.org/obo/NCBITaxon_436492 Coelurosauria http://purl.obolibrary.org/obo/NCBITaxon_480118 Eremoneura http://purl.obolibrary.org/obo/NCBITaxon_43733 Muscomorpha http://purl.obolibrary.org/obo/NCBITaxon_43741 Acalyptratae http://purl.obolibrary.org/obo/NCBITaxon_43738 Schizophora http://purl.obolibrary.org/obo/NCBITaxon_43738 Schizophora http://purl.obolibrary.org/obo/NCBITaxon_480117 Cyclorrhapha http://purl.obolibrary.org/obo/NCBITaxon_480117 Cyclorrhapha http://purl.obolibrary.org/obo/NCBITaxon_480118 Eremoneura http://purl.obolibrary.org/obo/NCBITaxon_85512 Dicondylia http://purl.obolibrary.org/obo/NCBITaxon_50557 Insecta http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea http://purl.obolibrary.org/obo/NCBITaxon_6231 Nematoda http://purl.obolibrary.org/obo/NCBITaxon_197563 Mandibulata http://purl.obolibrary.org/obo/NCBITaxon_6656 Arthropoda http://purl.obolibrary.org/obo/NCBITaxon_50557 Insecta http://purl.obolibrary.org/obo/NCBITaxon_6960 Hexapoda http://purl.obolibrary.org/obo/NCBITaxon_7203 Brachycera http://purl.obolibrary.org/obo/NCBITaxon_7147 Diptera http://purl.obolibrary.org/obo/NCBITaxon_43733 Muscomorpha http://purl.obolibrary.org/obo/NCBITaxon_7203 Brachycera http://purl.obolibrary.org/obo/NCBITaxon_33340 Neoptera http://purl.obolibrary.org/obo/NCBITaxon_7496 Pterygota http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata http://purl.obolibrary.org/obo/NCBITaxon_186623 Actinopteri http://purl.obolibrary.org/obo/NCBITaxon_7898 Actinopterygii http://purl.obolibrary.org/obo/NCBITaxon_30727 Cyprinoidei http://purl.obolibrary.org/obo/NCBITaxon_7952 Cypriniformes http://purl.obolibrary.org/obo/NCBITaxon_7955 Danio rerio http://purl.obolibrary.org/obo/NCBITaxon_7954 Danio http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_8287 Sarcopterygii http://purl.obolibrary.org/obo/NCBITaxon_32561 Sauria http://purl.obolibrary.org/obo/NCBITaxon_8457 Sauropsida http://purl.obolibrary.org/obo/NCBITaxon_436486 Dinosauria http://purl.obolibrary.org/obo/NCBITaxon_8492 Archosauria http://purl.obolibrary.org/obo/NCBITaxon_7496 Pterygota http://purl.obolibrary.org/obo/NCBITaxon_85512 Dicondylia http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_862507 Mus http://purl.obolibrary.org/obo/NCBITaxon_8825 Neognathae http://purl.obolibrary.org/obo/NCBITaxon_8782 Aves http://purl.obolibrary.org/obo/NCBITaxon_3078114 Neoaves http://purl.obolibrary.org/obo/NCBITaxon_8825 Neognathae http://purl.obolibrary.org/obo/NCBITaxon_6656 Arthropoda http://purl.obolibrary.org/obo/NCBITaxon_88770 Panarthropoda http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/UBERON_0009856 sac http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0018254 skeletal musculature http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0009911 lobule http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0012072 palatal part of dermatocranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0001978 parenchyma of pancreas http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma http://purl.obolibrary.org/obo/UBERON_0019190 mucous gland of lung http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland http://purl.obolibrary.org/obo/UBERON_0005945 neurocranial trabecula http://purl.obolibrary.org/obo/UBERON_0003932 cartilage element of chondrocranium http://purl.obolibrary.org/obo/UBERON_0001971 gastric juice http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland http://purl.obolibrary.org/obo/UBERON_0012466 extraembryonic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0034905 gland lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0000153 anterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0000154 posterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0005497 non-neural ectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0012361 internal anal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0012469 external anal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0006930 glandular cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://purl.obolibrary.org/obo/UBERON_0011272 embryonic skin basal layer http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0011592 future upper lip http://purl.obolibrary.org/obo/UBERON_0003235 epithelium of upper jaw http://purl.obolibrary.org/obo/UBERON_0011596 future lower lip http://purl.obolibrary.org/obo/UBERON_0003236 epithelium of lower jaw http://purl.obolibrary.org/obo/UBERON_0004468 set of muscles of vertebral column http://purl.obolibrary.org/obo/UBERON_0001015 musculature http://purl.obolibrary.org/obo/UBERON_0034729 sympathetic nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve http://purl.obolibrary.org/obo/UBERON_0006227 ethmoid bone primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0006236 tetrapod frontal bone primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0008947 respiratory primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0010375 pancreas dorsal primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0010376 pancreas ventral primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0000219 vertebral foramen of atlas http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen http://purl.obolibrary.org/obo/UBERON_0022281 epithelium of crypt of Lieberkuhn of large intestine http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0022280 epithelium of crypt of Lieberkuhn of small intestine http://purl.obolibrary.org/obo/UBERON_0011184 epithelium of crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0019189 carotid artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment http://purl.obolibrary.org/obo/UBERON_0001948 regional part of spinal cord http://purl.obolibrary.org/obo/UBERON_0022292 splenic arteriole http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel http://purl.obolibrary.org/obo/UBERON_0003076 posterior neural tube http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0003080 anterior neural tube http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005092 right horn of sinus venosus http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0006218 common atrial chamber http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0007237 1st arch mandibular component http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0007238 1st arch maxillary component http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0036301 vasculature of spleen http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ http://purl.obolibrary.org/obo/UBERON_0009708 dorsal pancreas http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0009709 ventral pancreas http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0011648 jaw muscle http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle http://purl.obolibrary.org/obo/UBERON_0036186 fibroelastic connective tissue http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0000963 head sensillum http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0011565 lumen of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0007690 early pharyngeal endoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0009644 trachea non-cartilage connective tissue http://purl.obolibrary.org/obo/UBERON_0003571 trachea connective tissue http://purl.obolibrary.org/obo/UBERON_0006304 future trigeminal ganglion http://purl.obolibrary.org/obo/UBERON_0003869 presumptive ganglion http://purl.obolibrary.org/obo/UBERON_0034710 spinal cord ventricular layer http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer http://purl.obolibrary.org/obo/UBERON_0009581 midbrain mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0009583 spinal cord mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0034709 hindbrain marginal layer http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0005239 basal plate metencephalon http://purl.obolibrary.org/obo/UBERON_0004064 neural tube basal plate http://purl.obolibrary.org/obo/UBERON_0005728 extraembryonic mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0005339 outflow tract pulmonary component http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract http://purl.obolibrary.org/obo/UBERON_0009196 indifferent external genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/UBERON_0004912 biliary bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0008836 liver bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/UBERON_0012416 respiratory system arterial smooth muscle http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0010291 layer of sclera http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0011234 fibrous membrane of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0015410 heart plus pericardium http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0009920 optic neural crest http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0009618 trunk paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0009722 entire pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0009881 anterior lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0009145 pharyngeal region of foregut http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0036290 myocardium of anterior wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0006566 left ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0036291 myocardium of anterior wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0006567 right ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0006241 future spinal cord http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0006596 presumptive blood http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0007026 presumptive gut http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0009615 midbrain hindbrain boundary neural plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0015128 subepicardial layer of epicardium http://purl.obolibrary.org/obo/UBERON_0007188 mesothelium of serous pericardium http://purl.obolibrary.org/obo/UBERON_0010528 pneumatic cavity of bone http://purl.obolibrary.org/obo/UBERON_0010527 cavity of bone organ http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0016570 lamina of gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0010191 aortic system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/UBERON_0001606 muscle of iris http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle http://purl.obolibrary.org/obo/UBERON_0005434 cervical region http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0018135 fibrocollagenous connective tissue http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0009292 embryonic nasal process http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence http://purl.obolibrary.org/obo/UBERON_0012485 cloacal villus http://purl.obolibrary.org/obo/UBERON_0012423 layer of microvilli http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0018692 dorsal side of post-anal tail http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/UBERON_0006056 posterior surface of head http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/UBERON_0022288 surface of eyeball http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/NCBITaxon_7900 Acipenseridae http://purl.obolibrary.org/obo/NCBITaxon_186622 Acipenseroidei http://purl.obolibrary.org/obo/NCBITaxon_7901 Acipenser http://purl.obolibrary.org/obo/NCBITaxon_124130 Acipenserini http://purl.obolibrary.org/obo/NCBITaxon_1206795 Lophotrochozoa http://purl.obolibrary.org/obo/NCBITaxon_2697495 Spiralia http://purl.obolibrary.org/obo/UBERON_0036288 anterior wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0036285 wall of left ventricle http://purl.obolibrary.org/obo/NCBITaxon_1547233 Xenoturbellidae http://purl.obolibrary.org/obo/NCBITaxon_110814 Xenoturbellida http://purl.obolibrary.org/obo/NCBITaxon_7227 Drosophila melanogaster http://purl.obolibrary.org/obo/NCBITaxon_32351 melanogaster subgroup http://purl.obolibrary.org/obo/NCBITaxon_2301116 Rhabditina http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida http://purl.obolibrary.org/obo/NCBITaxon_6239 Caenorhabditis elegans http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis http://purl.obolibrary.org/obo/NCBITaxon_8353 Xenopus http://purl.obolibrary.org/obo/NCBITaxon_8360 Xenopodinae http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/NCBITaxon_9605 Homo http://purl.obolibrary.org/obo/NCBITaxon_7954 Danio http://purl.obolibrary.org/obo/NCBITaxon_2743711 Danioninae http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts. http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue Any organ component layer that consists of smooth muscle tissue. http://purl.obolibrary.org/obo/UBERON_1000021 skin of face http://purl.obolibrary.org/obo/UBERON_0001084 skin of head A zone of skin that is part of the face. http://purl.obolibrary.org/obo/UBERON_1000024 parenchyma of spleen http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma A parenchyma that is part of a spleen. http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element Cartilage which is part of the axial skeleton. http://purl.obolibrary.org/obo/UBERON_2005260 fenestrated capillary http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse. http://purl.obolibrary.org/obo/UBERON_2007013 preplacodal ectoderm http://purl.obolibrary.org/obo/UBERON_0005497 non-neural ectoderm Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes. http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure http://purl.obolibrary.org/obo/UBERON_0003102 surface structure Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. http://purl.obolibrary.org/obo/UBERON_3000972 head external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the external head integument. http://purl.obolibrary.org/obo/UBERON_3000977 body external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the body integument. http://purl.obolibrary.org/obo/UBERON_3000982 tail external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the tail integument. http://purl.obolibrary.org/obo/UBERON_3010200 vasculature of respiratory integument http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel Blood vessels in respiratory skin. http://purl.obolibrary.org/obo/UBERON_4200230 surface of bone http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface An anatomical surface that is part of a bone. http://purl.obolibrary.org/obo/PR_000007499 fibroblast growth factor 8 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_P01730 T-cell surface glycoprotein CD4 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD4 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P01731 T-cell surface glycoprotein CD8 alpha chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P05555 integrin alpha-M (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-M that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P06127 T-cell surface glycoprotein CD5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P06332 T-cell surface glycoprotein CD4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD4 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P08571 monocyte differentiation antigen CD14 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD14 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P08920 T-cell surface antigen CD2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD2 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35461 lymphocyte antigen 6G (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 6G that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35918 vascular endothelial growth factor receptor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P37237 fibroblast growth factor 8 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 8 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0034945 excreted gas http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas Any gaseous product of an excretory process. http://purl.obolibrary.org/obo/UBERON_0034946 gas excreted from digestive tract http://purl.obolibrary.org/obo/UBERON_0034945 excreted gas Any excreted gas that is produced by the digestive tract. http://purl.obolibrary.org/obo/NBO_0000313 behavior process http://purl.obolibrary.org/obo/GO_0007610 behavior "The action, reaction, or performance of an organism in response to external or internal stimuli." [GO:GO\:0007610] http://purl.obolibrary.org/obo/UBERON_0035550 superficial vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers. http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that forms the outermost boundary of an anatomical structure. http://purl.obolibrary.org/obo/GO_0110020 regulation of actomyosin structure organization http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. http://purl.obolibrary.org/obo/GO_0150111 regulation of transepithelial transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of transepithelial transport. http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses. http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell http://purl.obolibrary.org/obo/CL_0000359 vascular associated smooth muscle cell A smooth muscle cell that is part of any blood vessel. http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the tracheobronchial tree. http://purl.obolibrary.org/obo/UBERON_8000009 Purkinje fiber network http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles. http://purl.obolibrary.org/obo/UBERON_8400021 liver serosa http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane Hepatic serous coat; peritoneal covering of the liver, enclosing almost all except for a triangular area on its posterior surface (the 'bare area of the liver') and a smaller area where the liver and gallbladder are in direct contact. http://purl.obolibrary.org/obo/UBERON_8400023 liver subserosa http://purl.obolibrary.org/obo/UBERON_0012375 subserosa Subserosal tissue of liver. A zone of areolar connective tissue lying beneath the serous coat of the liver and distinguished with difficulty from the fibrous capsule of Glisson. http://purl.obolibrary.org/obo/CHEBI_167559 glycan http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001. http://purl.obolibrary.org/obo/CHEBI_10545 electron http://purl.obolibrary.org/obo/CHEBI_36338 lepton Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV. http://purl.obolibrary.org/obo/CHEBI_30212 photon http://purl.obolibrary.org/obo/CHEBI_36341 boson Particle of zero charge, zero rest mass, spin quantum number 1, energy hnu and momentum hnu/c (h is the Planck constant, nu the frequency of radiation and c the speed of light), carrier of electromagnetic force. http://purl.obolibrary.org/obo/CHEBI_36338 lepton http://purl.obolibrary.org/obo/CHEBI_36340 fermion Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin). http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). http://purl.obolibrary.org/obo/CHEBI_17608 D-aldohexose http://purl.obolibrary.org/obo/CHEBI_4194 D-hexose Any D-aldose having a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/CHEBI_17634 D-glucose http://purl.obolibrary.org/obo/CHEBI_17608 D-aldohexose A glucose with D-configuration. http://purl.obolibrary.org/obo/CHEBI_26836 sulfuric acid http://purl.obolibrary.org/obo/CHEBI_33402 sulfur oxoacid A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom. http://purl.obolibrary.org/obo/CHEBI_33672 heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom. http://purl.obolibrary.org/obo/CHEBI_38077 polypyrrole http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound A compound composed of two or more pyrrole units. http://purl.obolibrary.org/obo/CHEBI_38323 cholinergic drug http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. http://purl.obolibrary.org/obo/CHEBI_51151 dipolar compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case. http://purl.obolibrary.org/obo/CHEBI_64047 food additive http://purl.obolibrary.org/obo/CHEBI_78295 food component Any substance which is added to food to preserve or enhance its flavour and/or appearance. http://purl.obolibrary.org/obo/CHEBI_36237 cholanic acid http://purl.obolibrary.org/obo/CHEBI_36278 cholanic acids A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24. http://purl.obolibrary.org/obo/CHEBI_36340 fermion http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi. http://purl.obolibrary.org/obo/CHEBI_36343 composite particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A subatomic particle known to have substructure (i.e. consisting of smaller particles). http://purl.obolibrary.org/obo/CHEBI_36344 hadron http://purl.obolibrary.org/obo/CHEBI_36343 composite particle Hadron is a subatomic particle which experiences the strong force. http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. http://purl.obolibrary.org/obo/CHEBI_5391 glucagon http://purl.obolibrary.org/obo/CHEBI_25905 peptide hormone A 29-amino acid peptide hormone consisting of His, Ser, Gln, Gly, Thr, Phe, Thr, Ser, Asp, Tyr, Ser, Lys, Tyr, Leu, Asp, Ser, Arg, Arg, Ala, Gln, Asp, Phe, Val, Gln, Trp, Leu, Met, Asn and Thr residues joined in sequence. http://purl.obolibrary.org/obo/CHEBI_64628 somatostatin http://purl.obolibrary.org/obo/CHEBI_25905 peptide hormone A fourteen-membered heterodetic cyclic peptide comprising the sequence Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys cyclised by a disulfide bridge between the two Cys residues at positions 3 and 14. http://purl.obolibrary.org/obo/CHEBI_64766 cationic group http://purl.obolibrary.org/obo/CHEBI_24433 group A group that carries an overall positive charge. http://purl.obolibrary.org/obo/CHEBI_64767 anionic group http://purl.obolibrary.org/obo/CHEBI_24433 group A group that carries an overall negative charge. http://purl.obolibrary.org/obo/CHEBI_64898 anionic amino-acid residue http://purl.obolibrary.org/obo/CHEBI_64775 organic anionic group An amino-acid residue carrying an overall negative charge. http://purl.obolibrary.org/obo/CHEBI_75787 prokaryotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea. http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*). http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection http://purl.obolibrary.org/obo/GO_0042995 cell projection A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/CHEBI_138366 bile acids http://purl.obolibrary.org/obo/CHEBI_36078 cholanoid Any member of a group of hydroxy steroids occuring in bile, where they are present as the sodium salts of their amides with glycine or taurine. In mammals bile acids almost invariably have 5beta-configuration, while in lower vertebrates, some bile acids, known as allo-bile acids, have 5alpha-configuration. http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the rate, frequency or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0110116 regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://purl.obolibrary.org/obo/GO_0110117 positive regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046534 positive regulation of photoreceptor cell differentiation Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://purl.obolibrary.org/obo/GO_0110118 negative regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046533 negative regulation of photoreceptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://purl.obolibrary.org/obo/GO_0120187 positive regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin Any process that activates or increases the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_0120188 regulation of bile acid secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0120189 positive regulation of bile acid secretion http://purl.obolibrary.org/obo/GO_0032892 positive regulation of organic acid transport Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0120190 negative regulation of bile acid secretion http://purl.obolibrary.org/obo/GO_0032891 negative regulation of organic acid transport Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0140236 translation at presynapse http://purl.obolibrary.org/obo/GO_0140241 translation at synapse Translation that occurs at the presynapse. http://purl.obolibrary.org/obo/GO_0140237 translation at presynapse, modulating chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0140236 translation at presynapse Translation that occurs at the presynapse, and that modulates chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0140241 translation at synapse http://purl.obolibrary.org/obo/GO_0006412 translation Translation that occurs at the synapse. http://purl.obolibrary.org/obo/GO_0140242 translation at postsynapse http://purl.obolibrary.org/obo/GO_0140241 translation at synapse Translation that occurs at the postsynapse. http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that regulates translation occurring at the synapse. http://purl.obolibrary.org/obo/GO_0140245 regulation of translation at postsynapse http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse Any process that regulates translation occurring at the postsynapse. http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein at a synapse. http://purl.obolibrary.org/obo/GO_0140247 protein catabolic process at presynapse http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse. http://purl.obolibrary.org/obo/GO_0140249 protein catabolic process at postsynapse http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse. http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse. http://purl.obolibrary.org/obo/GO_0140251 regulation protein catabolic process at presynapse http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse. http://purl.obolibrary.org/obo/GO_0140252 regulation protein catabolic process at postsynapse http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse. http://purl.obolibrary.org/obo/CHEBI_142163 24G7 epitope http://purl.obolibrary.org/obo/CHEBI_24433 group An antigenic epitope recognized by an anti-bilirubin monoclonal antibody designated 24G7. A substructure of bilirubin IXalpha, it is the region containing the oxo group at C-1, the methyl group at C-2, C-(4, 5, 6, 9), and N-21 and -22. http://purl.obolibrary.org/obo/GO_0140572 vacuole fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a vacuole within a cell to form two or more separate vacuoles. http://purl.obolibrary.org/obo/UBERON_8410068 capillary of small intestine http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of a small intestine. http://purl.obolibrary.org/obo/UBERON_8480074 skin of gonad http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin part of some gonad. http://purl.obolibrary.org/obo/GO_0160093 chordate pharynx development http://purl.obolibrary.org/obo/GO_0060465 pharynx development The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/UBERON_0016514 cavity of left ventricle http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the left ventricle of the heart. http://purl.obolibrary.org/obo/UBERON_0007831 pectoral girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons. http://purl.obolibrary.org/obo/GO_0110077 vesicle-mediated intercellular transport http://purl.obolibrary.org/obo/GO_0010496 intercellular transport A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane. http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength. http://purl.obolibrary.org/obo/UBERON_8600006 visceral striated muscle tissue http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue A striated muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/UBERON_0003071 eye primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles. http://purl.obolibrary.org/obo/GO_0099156 cell-cell signaling via exosome http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling in which the ligand is carried between cells by an exosome. http://purl.obolibrary.org/obo/GO_0099157 trans-synaptic signaling via exosome http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Transynaptic signaling in which the ligand is carried across the synapse by an exosome. http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling Any process that modulates the frequency, rate or extent of trans-synaptic signaling. http://purl.obolibrary.org/obo/GO_0099173 postsynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. http://purl.obolibrary.org/obo/GO_0099174 regulation of presynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a presynapse. http://purl.obolibrary.org/obo/GO_0099187 presynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton. http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton. http://purl.obolibrary.org/obo/GO_0140253 cell-cell fusion http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. http://purl.obolibrary.org/obo/CL_0009053 stromal cell of anorectum lamina propria http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the anorectum. http://purl.obolibrary.org/obo/UBERON_8480025 skin of clavicle region http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is above the clavicle zone in the pectoral girdle region. http://purl.obolibrary.org/obo/CL_4033002 neuroendocrine cell of epithelium of crypt of Lieberkuhn http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell A(n) neuroendocrine cell that is part of a(n) epithelium of crypt of Lieberkuhn. http://purl.obolibrary.org/obo/GO_0000011 vacuole inheritance http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. http://purl.obolibrary.org/obo/GO_0000070 mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. http://purl.obolibrary.org/obo/GO_0000139 Golgi membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding any of the compartments of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0000228 nuclear chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. http://purl.obolibrary.org/obo/GO_0000271 polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0000272 polysaccharide catabolic process http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle http://purl.obolibrary.org/obo/GO_0007049 cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. http://purl.obolibrary.org/obo/GO_0000280 nuclear division http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome http://purl.obolibrary.org/obo/GO_0005840 ribosome A ribosome contained within a subcellular membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0000740 nuclear membrane fusion http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The joining of 2 or more lipid bilayer membranes that surround the nucleus. http://purl.obolibrary.org/obo/GO_0000741 karyogamy http://purl.obolibrary.org/obo/GO_0048284 organelle fusion The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. http://purl.obolibrary.org/obo/GO_0000768 syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0006949 syncytium formation The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0000785 chromatin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. http://purl.obolibrary.org/obo/GO_0000792 heterochromatin http://purl.obolibrary.org/obo/GO_0000785 chromatin A compact and highly condensed form of chromatin that is refractory to transcription. http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process in which the size or shape of a cell is generated and organized. http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/GO_0001501 skeletal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). http://purl.obolibrary.org/obo/GO_0001503 ossification http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0001507 acetylcholine catabolic process in synaptic cleft http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission. http://purl.obolibrary.org/obo/GO_0001508 action potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. http://purl.obolibrary.org/obo/GO_0001525 angiogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0001555 oocyte growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/GO_0001556 oocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0001560 regulation of cell growth by extracellular stimulus http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. http://purl.obolibrary.org/obo/GO_0001568 blood vessel development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0001569 branching involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0001578 microtubule bundle formation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that results in a parallel arrangement of microtubules. http://purl.obolibrary.org/obo/GO_0001654 eye development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. http://purl.obolibrary.org/obo/GO_0001655 urogenital system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001659 temperature homeostasis http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis A homeostatic process in which an organism modulates its internal body temperature. http://purl.obolibrary.org/obo/GO_0001666 response to hypoxia http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration Cell migration that is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0001674 female germ cell nucleus http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus The nucleus of the female germ cell, a reproductive cell in females. http://purl.obolibrary.org/obo/GO_0001677 formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/GO_0001678 intracellular glucose homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of glucose within a cell. http://purl.obolibrary.org/obo/GO_0001696 gastric acid secretion http://purl.obolibrary.org/obo/GO_0046717 acid secretion The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0001700 embryonic development via the syncytial blastoderm http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0001701 in utero embryonic development http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the ectoderm, mesoderm and endoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001705 ectoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of ectoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001706 endoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of the endoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0001743 lens placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The initial developmental process that will lead to the formation of an eye. http://purl.obolibrary.org/obo/GO_0001745 compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0001751 compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell. http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. http://purl.obolibrary.org/obo/GO_0001756 somitogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0001816 cytokine production http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate, or extent of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001818 negative regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the rate of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001819 positive regulation of cytokine production http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001820 serotonin secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. http://purl.obolibrary.org/obo/GO_0001824 blastocyst development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/GO_0001825 blastocyst formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a blastocyst from a solid ball of cells known as a morula. http://purl.obolibrary.org/obo/GO_0001826 inner cell mass cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell. http://purl.obolibrary.org/obo/GO_0001829 trophectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. http://purl.obolibrary.org/obo/GO_0001831 trophectodermal cellular morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The morphogenesis of trophectoderm cells. http://purl.obolibrary.org/obo/GO_0001832 blastocyst growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. http://purl.obolibrary.org/obo/GO_0001833 inner cell mass cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the inner cell mass. http://purl.obolibrary.org/obo/GO_0001834 trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the trophectoderm. http://purl.obolibrary.org/obo/GO_0001837 epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The morphogenesis of an embryonic epithelium into a tube-shaped structure. http://purl.obolibrary.org/obo/GO_0001839 neural plate morphogenesis http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. http://purl.obolibrary.org/obo/GO_0001840 neural plate development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0001841 neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0001842 neural fold formation http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. http://purl.obolibrary.org/obo/GO_0001885 endothelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The progression of an endothelial cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001886 endothelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. http://purl.obolibrary.org/obo/GO_0001889 liver development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/GO_0001936 regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001937 negative regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001938 positive regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001944 vasculature development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. http://purl.obolibrary.org/obo/GO_0001955 blood vessel maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0001956 positive regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/GO_0001957 intramembranous ossification http://purl.obolibrary.org/obo/GO_0036072 direct ossification Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. http://purl.obolibrary.org/obo/GO_0002011 morphogenesis of an epithelial sheet http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. http://purl.obolibrary.org/obo/GO_0002027 regulation of heart rate http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the frequency or rate of heart contraction. http://purl.obolibrary.org/obo/GO_0002028 regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0002052 positive regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation Any process that activates or increases the rate of neuroblast proliferation. http://purl.obolibrary.org/obo/GO_0002053 positive regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002068 glandular epithelial cell development http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/GO_0002071 glandular epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002072 optic cup morphogenesis involved in camera-type eye development http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002085 inhibition of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/GO_0002087 regulation of respiratory gaseous exchange by nervous system process http://purl.obolibrary.org/obo/GO_0050877 nervous system process A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. http://purl.obolibrary.org/obo/GO_0002088 lens development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002089 lens morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002119 nematode larval development http://purl.obolibrary.org/obo/GO_0002164 larval development The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. http://purl.obolibrary.org/obo/GO_0002164 larval development http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters. http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. http://purl.obolibrary.org/obo/GO_0002252 immune effector process http://purl.obolibrary.org/obo/GO_0002376 immune system process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0002318 myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages. http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002376 immune system process http://purl.obolibrary.org/obo/GO_0008150 biological process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. http://purl.obolibrary.org/obo/GO_0002384 hepatic immune response http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response An immune response taking place in the liver. http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010467 gene expression The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002252 immune effector process Any process involved in the carrying out of an immune response by a leukocyte. http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a myeloid leukocyte. http://purl.obolibrary.org/obo/GO_0002520 immune system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0002521 leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002698 negative regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002699 positive regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002701 negative regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002702 positive regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002704 negative regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002705 positive regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/GO_0002719 negative regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. http://purl.obolibrary.org/obo/GO_0002720 positive regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002762 negative regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002763 positive regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002790 peptide secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a peptide from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport Any process that modulates the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002792 negative regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002793 positive regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002831 regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002832 negative regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002833 positive regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002888 positive regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002932 tendon sheath development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. http://purl.obolibrary.org/obo/GO_0003002 regionalization http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. http://purl.obolibrary.org/obo/GO_0003007 heart morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0003008 system process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. http://purl.obolibrary.org/obo/GO_0003009 skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. http://purl.obolibrary.org/obo/GO_0003012 muscle system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. http://purl.obolibrary.org/obo/GO_0003013 circulatory system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. http://purl.obolibrary.org/obo/GO_0003014 renal system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). http://purl.obolibrary.org/obo/GO_0003015 heart process http://purl.obolibrary.org/obo/GO_0003013 circulatory system process A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0003016 respiratory system process http://purl.obolibrary.org/obo/GO_0003008 system process A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0003096 renal sodium ion transport http://purl.obolibrary.org/obo/GO_0006814 sodium ion transport The directed movement of sodium ions (Na+) by the renal system. http://purl.obolibrary.org/obo/GO_0003131 mesodermal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from mesodermal cells to endodermal cells. http://purl.obolibrary.org/obo/GO_0003133 endodermal-mesodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from endodermal cells to mesodermal cells. http://purl.obolibrary.org/obo/GO_0003142 cardiogenic plate morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. http://purl.obolibrary.org/obo/GO_0003143 embryonic heart tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/GO_0003144 embryonic heart tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/GO_0003145 embryonic heart tube formation via epithelial folding http://purl.obolibrary.org/obo/GO_0003144 embryonic heart tube formation The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis. http://purl.obolibrary.org/obo/GO_0003148 outflow tract septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. http://purl.obolibrary.org/obo/GO_0003149 membranous septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. http://purl.obolibrary.org/obo/GO_0003150 muscular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. http://purl.obolibrary.org/obo/GO_0003151 outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/GO_0003152 morphogenesis of an epithelial fold involved in embryonic heart tube formation http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation. http://purl.obolibrary.org/obo/GO_0003156 regulation of animal organ formation http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. http://purl.obolibrary.org/obo/GO_0003157 endocardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0003158 endothelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0003159 morphogenesis of an endothelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0003160 endocardium morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0003161 cardiac conduction system development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. http://purl.obolibrary.org/obo/GO_0003162 atrioventricular node development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. http://purl.obolibrary.org/obo/GO_0003163 sinoatrial node development http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. http://purl.obolibrary.org/obo/GO_0003164 His-Purkinje system development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0003165 Purkinje myocyte development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. http://purl.obolibrary.org/obo/GO_0003168 Purkinje myocyte differentiation http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. http://purl.obolibrary.org/obo/GO_0003169 coronary vein morphogenesis http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis The process in which the anatomical structures of veins of the heart are generated and organized. http://purl.obolibrary.org/obo/GO_0003197 endocardial cushion development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003203 endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003204 cardiac skeleton development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003212 cardiac left atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the left cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/GO_0003213 cardiac right atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the right cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/GO_0003214 cardiac left ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the left cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/GO_0003215 cardiac right ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the right cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/GO_0003216 cardiac left atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. http://purl.obolibrary.org/obo/GO_0003217 cardiac right atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. http://purl.obolibrary.org/obo/GO_0003218 cardiac left ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/GO_0003219 cardiac right ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/GO_0003220 left ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003221 right ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0061384 heart trabecula morphogenesis The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003225 left ventricular trabecular myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized. http://purl.obolibrary.org/obo/GO_0003227 right ventricular trabecular myocardium morphogenesis http://purl.obolibrary.org/obo/GO_0003222 ventricular trabecula myocardium morphogenesis The process in which the anatomical structures of the right ventricular myocardium are generated and organized. http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003230 cardiac atrium development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003231 cardiac ventricle development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003235 sinus venosus development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003236 sinus venosus morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003237 sinus venosus formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003241 growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis Developmental growth that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003245 cardiac muscle tissue growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003248 heart capillary growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. http://purl.obolibrary.org/obo/GO_0003272 endocardial cushion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003273 cell migration involved in endocardial cushion formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003275 apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/GO_0003277 apoptotic process involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003281 ventricular septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the ventricular septum over time from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003283 atrial septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the atrial septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003292 cardiac septum cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which an endocardial cushion cell becomes a cell of a cardiac septum. http://purl.obolibrary.org/obo/GO_0003298 physiological muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. http://purl.obolibrary.org/obo/GO_0003301 physiological cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. http://purl.obolibrary.org/obo/GO_0003309 type B pancreatic cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0003310 pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon. http://purl.obolibrary.org/obo/GO_0003311 pancreatic D cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin. http://purl.obolibrary.org/obo/GO_0003312 pancreatic PP cell differentiation http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. http://purl.obolibrary.org/obo/GO_0003313 heart rudiment development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/GO_0003314 heart rudiment morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the heart rudiment are generated and organized. http://purl.obolibrary.org/obo/GO_0003315 heart rudiment formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the heart rudiment. http://purl.obolibrary.org/obo/GO_0003322 pancreatic A cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon. http://purl.obolibrary.org/obo/GO_0003323 type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0003324 pancreatic D cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin. http://purl.obolibrary.org/obo/GO_0003325 pancreatic PP cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide. http://purl.obolibrary.org/obo/GO_0003330 regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003331 positive regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003332 negative regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The process in which an amino acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_0003342 proepicardium development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. http://purl.obolibrary.org/obo/GO_0003343 septum transversum development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. http://purl.obolibrary.org/obo/GO_0003344 pericardium morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the pericardium is generated and organized. http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. http://purl.obolibrary.org/obo/GO_0003357 noradrenergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline. http://purl.obolibrary.org/obo/GO_0003358 noradrenergic neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0003360 brainstem development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. http://purl.obolibrary.org/obo/GO_0003361 noradrenergic neuron differentiation involved in brainstem development http://purl.obolibrary.org/obo/GO_0003357 noradrenergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem. http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. http://purl.obolibrary.org/obo/GO_0003379 establishment of cell polarity involved in gastrulation cell migration http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/GO_0003380 establishment or maintenance of cytoskeleton polarity involved in gastrulation http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/GO_0003381 epithelial cell morphogenesis involved in gastrulation http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0003403 optic vesicle formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/GO_0003404 optic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/GO_0003407 neural retina development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0003411 cell motility involved in camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048870 cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye. http://purl.obolibrary.org/obo/GO_0003413 chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0003414 chondrocyte morphogenesis involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized. http://purl.obolibrary.org/obo/GO_0003416 endochondral bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/GO_0003433 chondrocyte development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity http://purl.obolibrary.org/obo/BFO_0000015 process A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. http://purl.obolibrary.org/obo/GO_0005622 intracellular anatomical structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. http://purl.obolibrary.org/obo/GO_0005634 nucleus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. http://purl.obolibrary.org/obo/GO_0005694 chromosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. http://purl.obolibrary.org/obo/GO_0005737 cytoplasm http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0005773 vacuole http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. http://purl.obolibrary.org/obo/GO_0005774 vacuolar membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. http://purl.obolibrary.org/obo/GO_0005775 vacuolar lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed within the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0005840 ribosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. http://purl.obolibrary.org/obo/GO_0005881 cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0005886 plasma membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/GO_0005976 polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0005977 glycogen metabolic process http://purl.obolibrary.org/obo/GO_0044042 glucan metabolic process The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006325 chromatin organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. http://purl.obolibrary.org/obo/GO_0006401 RNA catabolic process http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/GO_0006412 translation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. http://purl.obolibrary.org/obo/GO_0006413 translational initiation http://purl.obolibrary.org/obo/GO_0008152 metabolic process The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/GO_0006414 translational elongation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. http://purl.obolibrary.org/obo/GO_0006415 translational termination http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/GO_0006790 sulfur compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0006814 sodium ion transport http://purl.obolibrary.org/obo/GO_0030001 metal ion transport The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/GO_0006837 serotonin transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. http://purl.obolibrary.org/obo/GO_0006865 amino acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006869 lipid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. http://purl.obolibrary.org/obo/GO_0006915 apoptotic process http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction Any process that modulates the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction http://purl.obolibrary.org/obo/GO_0006936 muscle contraction A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. http://purl.obolibrary.org/obo/GO_0006949 syncytium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. http://purl.obolibrary.org/obo/GO_0006950 response to stress http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0006955 immune response http://purl.obolibrary.org/obo/GO_0002376 immune system process Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. http://purl.obolibrary.org/obo/GO_0006997 nucleus organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. http://purl.obolibrary.org/obo/GO_0007009 plasma membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0007033 vacuole organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The aggregation, arrangement and bonding together of a set of components to form a junction between cells. http://purl.obolibrary.org/obo/GO_0007049 cell cycle http://purl.obolibrary.org/obo/GO_0009987 cellular process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. http://purl.obolibrary.org/obo/GO_0007097 nuclear migration http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the nucleus to a specific location within a cell. http://purl.obolibrary.org/obo/GO_0007154 cell communication http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0007165 signal transduction http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling http://purl.obolibrary.org/obo/GO_0023052 signaling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. http://purl.obolibrary.org/obo/GO_0007271 synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0007369 gastrulation http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/GO_0007389 pattern specification process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0007398 ectoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. http://purl.obolibrary.org/obo/GO_0007405 neuroblast proliferation http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0007423 sensory organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0007492 endoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. http://purl.obolibrary.org/obo/GO_0007507 heart development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0007519 skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. http://purl.obolibrary.org/obo/GO_0007585 respiratory gaseous exchange by respiratory system http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/GO_0007610 behavior http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. http://purl.obolibrary.org/obo/GO_0008150 biological process http://purl.obolibrary.org/obo/BFO_0000015 process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. http://purl.obolibrary.org/obo/GO_0008206 bile acid metabolic process http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation http://purl.obolibrary.org/obo/GO_0009987 cellular process The multiplication or reproduction of cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008324 monoatomic cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015075 monoatomic ion transmembrane transporter activity Enables the transfer of cation from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008514 organic anion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0008585 female gonad development http://purl.obolibrary.org/obo/GO_0008406 gonad development The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0008652 amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0009063 amino acid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0009306 protein secretion http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region The controlled release of proteins from a cell. http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. http://purl.obolibrary.org/obo/GO_0009620 response to fungus http://purl.obolibrary.org/obo/GO_0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching http://purl.obolibrary.org/obo/GO_0009790 embryo development The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0009888 tissue development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. http://purl.obolibrary.org/obo/GO_0009914 hormone transport http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009967 positive regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009968 negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0008150 biological process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. http://purl.obolibrary.org/obo/GO_0010002 cardioblast differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0010467 gene expression http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010604 positive regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010605 negative regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010668 ectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The cellular component assembly that is part of the initial shaping of the component during its developmental progression. http://purl.obolibrary.org/obo/GO_0010959 regulation of metal ion transport http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0012501 programmed cell death http://purl.obolibrary.org/obo/GO_0008219 cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. http://purl.obolibrary.org/obo/GO_0014020 primary neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development http://purl.obolibrary.org/obo/GO_0048864 stem cell development The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014075 response to amine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003012 muscle system process The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/GO_0015103 inorganic anion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015318 inorganic molecular entity transmembrane transporter activity Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. http://purl.obolibrary.org/obo/GO_0015629 actin cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. http://purl.obolibrary.org/obo/GO_0015630 microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. http://purl.obolibrary.org/obo/GO_0015698 inorganic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015711 organic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015833 peptide transport http://purl.obolibrary.org/obo/GO_0042886 amide transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0016049 cell growth http://purl.obolibrary.org/obo/GO_0040007 growth The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/GO_0016050 vesicle organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/GO_0016301 kinase activity http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of embryonic epithelia are generated and organized. http://purl.obolibrary.org/obo/GO_0016477 cell migration http://purl.obolibrary.org/obo/GO_0048870 cell motility The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0019953 sexual reproduction http://purl.obolibrary.org/obo/GO_0022414 reproductive process A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). http://purl.obolibrary.org/obo/GO_0021915 neural tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. http://purl.obolibrary.org/obo/GO_0022402 cell cycle process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism http://purl.obolibrary.org/obo/GO_0009987 cellular process A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0008150 biological process A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. http://purl.obolibrary.org/obo/GO_0022600 digestive system process http://purl.obolibrary.org/obo/GO_0003008 system process A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The aggregation, arrangement and bonding together of a cellular component. http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023056 positive regulation of signaling http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023057 negative regulation of signaling http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0030001 metal ion transport http://purl.obolibrary.org/obo/GO_0006812 monoatomic cation transport The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity The specification and formation of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. http://purl.obolibrary.org/obo/GO_0030141 secretory granule http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron. http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolic process The chemical reactions and pathways involving glycosaminoglycans, any of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation http://purl.obolibrary.org/obo/GO_0051276 chromosome organization The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility Any process that activates or increases the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030473 nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a secretory granule. http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. http://purl.obolibrary.org/obo/GO_0030857 negative regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0031018 endocrine pancreas development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. http://purl.obolibrary.org/obo/GO_0031128 developmental induction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). http://purl.obolibrary.org/obo/GO_0031175 neuron projection development http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0031252 cell leading edge http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The area of a motile cell closest to the direction of movement. http://purl.obolibrary.org/obo/GO_0031333 negative regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031334 positive regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle A vesicle found in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0031981 nuclear lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed by the nuclear inner membrane. http://purl.obolibrary.org/obo/GO_0032101 regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032432 actin filament bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process http://purl.obolibrary.org/obo/GO_0008150 biological process Any biological process, occurring at the level of a multicellular organism, pertinent to its function. http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0008150 biological process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0032774 RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. http://purl.obolibrary.org/obo/GO_0032940 secretion by cell http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a cell. http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization The disaggregation of a protein-containing macromolecular complex into its constituent components. http://purl.obolibrary.org/obo/GO_0032988 protein-RNA complex disassembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The disaggregation of a protein-RNA complex into its constituent components. http://purl.obolibrary.org/obo/GO_0032989 cellular anatomical entity morphogenesis http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system. http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex http://purl.obolibrary.org/obo/GO_0005575 cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0034248 regulation of amide metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034249 negative regulation of amide metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034250 positive regulation of amide metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0035050 embryonic heart tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/GO_0035282 segmentation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. http://purl.obolibrary.org/obo/GO_0035883 enteroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. http://purl.obolibrary.org/obo/GO_0035987 endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/GO_0035989 tendon development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. http://purl.obolibrary.org/obo/GO_0036072 direct ossification http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. http://purl.obolibrary.org/obo/GO_0036093 germ cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. http://purl.obolibrary.org/obo/GO_0040007 growth http://purl.obolibrary.org/obo/GO_0008150 biological process The increase in size or mass of an entire organism, a part of an organism or a cell. http://purl.obolibrary.org/obo/GO_0040008 regulation of growth http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. http://purl.obolibrary.org/obo/GO_0042074 cell migration involved in gastrulation http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0042221 response to chemical http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0042254 ribosome biogenesis http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. http://purl.obolibrary.org/obo/GO_0042255 ribosome assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. http://purl.obolibrary.org/obo/GO_0042401 biogenic amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0042402 biogenic amine catabolic process http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0042592 homeostatic process http://purl.obolibrary.org/obo/GO_0008150 biological process Any biological process involved in the maintenance of an internal steady state. http://purl.obolibrary.org/obo/GO_0042593 glucose homeostasis http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. http://purl.obolibrary.org/obo/GO_0042641 actomyosin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Any complex of actin, myosin, and accessory proteins. http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the occurrence or rate of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0042995 cell projection http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. http://purl.obolibrary.org/obo/GO_0043010 camera-type eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/GO_0043043 peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus The nucleus of a germ cell, a reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/GO_0043083 synaptic cleft http://purl.obolibrary.org/obo/GO_0005576 extracellular region The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. http://purl.obolibrary.org/obo/GO_0043171 peptide catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. http://purl.obolibrary.org/obo/GO_0043207 response to external biotic stimulus http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. http://purl.obolibrary.org/obo/GO_0043226 organelle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/GO_0043467 regulation of generation of precursor metabolites and energy http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation http://purl.obolibrary.org/obo/GO_0003012 muscle system process A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0043603 amide metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0043604 amide biosynthetic process http://purl.obolibrary.org/obo/GO_0043603 amide metabolic process The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/GO_0043605 amide catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. http://purl.obolibrary.org/obo/GO_0044065 regulation of respiratory system process http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. http://purl.obolibrary.org/obo/GO_0044272 sulfur compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0044273 sulfur compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione. http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0045026 plasma membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate. http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045638 negative regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045639 positive regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0045822 negative regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/GO_0045823 positive regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that activates or increases the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/GO_0045839 negative regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. http://purl.obolibrary.org/obo/GO_0045920 negative regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0045921 positive regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0046219 indolalkylamine biosynthetic process http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group. http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046620 regulation of organ growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046717 acid secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of acid by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0046879 hormone secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0006810 transport The controlled release of a substance by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0046928 regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell. http://purl.obolibrary.org/obo/GO_0048209 regulation of vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0048284 organelle fusion http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of a single organelle from two or more organelles. http://purl.obolibrary.org/obo/GO_0048285 organelle fission http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of two or more organelles by division of one organelle. http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance http://purl.obolibrary.org/obo/GO_0006996 organelle organization The partitioning of organelles between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of the mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048333 mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. http://purl.obolibrary.org/obo/GO_0048368 lateral mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048468 cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place. http://purl.obolibrary.org/obo/GO_0048469 cell maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development. http://purl.obolibrary.org/obo/GO_0048513 animal organ development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. http://purl.obolibrary.org/obo/GO_0048589 developmental growth http://purl.obolibrary.org/obo/GO_0040007 growth The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the eye are generated and organized. http://purl.obolibrary.org/obo/GO_0048593 camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/GO_0048596 embryonic camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048048 embryonic eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during embryonic development. http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. http://purl.obolibrary.org/obo/GO_0048599 oocyte development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. http://purl.obolibrary.org/obo/GO_0048645 animal organ formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048666 neuron development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. http://purl.obolibrary.org/obo/GO_0048699 generation of neurons http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. http://purl.obolibrary.org/obo/GO_0048705 skeletal system morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skeleton are generated and organized. http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tissue are generated and organized. http://purl.obolibrary.org/obo/GO_0048731 system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0048732 gland development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048749 compound eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development http://purl.obolibrary.org/obo/GO_0032502 developmental process The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048858 cell projection morphogenesis http://purl.obolibrary.org/obo/GO_0030030 cell projection organization The process in which the anatomical structures of a cell projection are generated and organized. http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0032502 developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0048870 cell motility http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050769 positive regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0050806 positive regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/GO_0050808 synapse organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_0050877 nervous system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the neurological system. http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of body fluids. http://purl.obolibrary.org/obo/GO_0050881 musculoskeletal movement http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. http://purl.obolibrary.org/obo/GO_0050886 endocrine process http://purl.obolibrary.org/obo/GO_0003008 system process The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. http://purl.obolibrary.org/obo/GO_0050905 neuromuscular process http://purl.obolibrary.org/obo/GO_0050877 nervous system process Any process pertaining to the functions of the nervous and muscular systems of an organism. http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051216 cartilage development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051254 positive regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0045935 positive regulation of nucleobase-containing compound metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051258 protein polymerization http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. http://purl.obolibrary.org/obo/GO_0051276 chromosome organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. http://purl.obolibrary.org/obo/GO_0051301 cell division http://purl.obolibrary.org/obo/GO_0009987 cellular process The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. http://purl.obolibrary.org/obo/GO_0051321 meiotic cell cycle http://purl.obolibrary.org/obo/GO_0022414 reproductive process Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. http://purl.obolibrary.org/obo/GO_0051493 regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051590 positive regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051707 response to other organism http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0051955 regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051956 negative regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051957 positive regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the anatomical structures of cardiac muscle tissue are generated and organized. http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of a chemical within a cell. http://purl.obolibrary.org/obo/GO_0060039 pericardium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. http://purl.obolibrary.org/obo/GO_0060041 retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/GO_0060231 mesenchymal to epithelial transition http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0060350 endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. http://purl.obolibrary.org/obo/GO_0060351 cartilage development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. http://purl.obolibrary.org/obo/GO_0060379 cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. http://purl.obolibrary.org/obo/GO_0060412 ventricular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. http://purl.obolibrary.org/obo/GO_0060413 atrial septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. http://purl.obolibrary.org/obo/GO_0060419 heart growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060429 epithelium development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of cartilage are generated and organized. http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development http://purl.obolibrary.org/obo/GO_0007517 muscle organ development The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development Any apoptotic process that contributes to the shaping of an anatomical structure. http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The morphogenetic process in which an epithelial sheet bends along a linear axis. http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0060795 cell fate commitment involved in formation of primary germ layer http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. http://purl.obolibrary.org/obo/GO_0060841 venous blood vessel development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. http://purl.obolibrary.org/obo/GO_0060900 embryonic camera-type eye formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. http://purl.obolibrary.org/obo/GO_0060914 heart formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. http://purl.obolibrary.org/obo/GO_0060976 coronary vasculature development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0061008 hepaticobiliary system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. http://purl.obolibrary.org/obo/GO_0061025 membrane fusion http://purl.obolibrary.org/obo/GO_0061024 membrane organization The membrane organization process that joins two lipid bilayers to form a single membrane. http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061049 cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061053 somite development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. http://purl.obolibrary.org/obo/GO_0061309 cardiac neural crest cell development involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061384 heart trabecula morphogenesis http://purl.obolibrary.org/obo/GO_0061383 trabecula morphogenesis The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/GO_0061448 connective tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of a connective tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. http://purl.obolibrary.org/obo/GO_0070278 extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. http://purl.obolibrary.org/obo/GO_0070483 detection of hypoxia http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a leukocyte population by cell division. http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0070925 organelle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0071248 cellular response to metal ion http://purl.obolibrary.org/obo/GO_0010038 response to metal ion Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation http://purl.obolibrary.org/obo/GO_0021700 developmental maturation A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0071709 membrane assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a membrane. http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/GO_0072001 renal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation http://purl.obolibrary.org/obo/GO_0035148 tube formation The developmental process pertaining to the initial formation of an epithelial tube. http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. http://purl.obolibrary.org/obo/GO_0072348 sulfur compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of two lipid bilayers to form a single organelle membrane. http://purl.obolibrary.org/obo/GO_0097164 ammonium ion metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving the ammonium ion. http://purl.obolibrary.org/obo/GO_0097190 apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer that forms the outer-most layer of an organelle. http://purl.obolibrary.org/obo/GO_0098657 import into cell http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/GO_0098773 skin epidermis development http://purl.obolibrary.org/obo/GO_0008544 epidermis development The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is part of a membrane. http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098801 regulation of renal system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_0098868 bone growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a bone that contributes to the shaping of that bone. http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901607 alpha-amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways resulting in the formation of an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901682 sulfur compound transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a sulfur compound from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902275 regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process. http://purl.obolibrary.org/obo/GO_1902692 regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of neuroblast proliferation. http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process that is involved in anatomical structure development. http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process that is part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process http://purl.obolibrary.org/obo/GO_0022402 cell cycle process A process that is part of the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903055 positive regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion Any process that modulates the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1905039 carboxylic acid transmembrane transport http://purl.obolibrary.org/obo/GO_1903825 organic acid transmembrane transport The process in which carboxylic acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_1905145 cellular response to acetylcholine http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905331 negative regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of multicellular organismal development. http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_2000114 regulation of establishment of cell polarity http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity. http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000137 negative regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000138 positive regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000648 positive regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that activates or increases the frequency, rate or extent of stem cell proliferation. http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of heart morphogenesis. http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0019226 transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0050877 nervous system process The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. http://purl.obolibrary.org/obo/GO_0019228 neuronal action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a neuron. http://purl.obolibrary.org/obo/GO_0019233 sensory perception of pain http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. A painful stimulus is any physical or chemical event that has the potential to cause tissue damage (actual or perceived) and activates the nociceptive system. http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0019413 acetate biosynthetic process http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid. http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/GO_0021501 prechordal plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. http://purl.obolibrary.org/obo/GO_0021510 spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. http://purl.obolibrary.org/obo/GO_0021514 ventral spinal cord interneuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021515 cell differentiation in spinal cord http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021517 ventral spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021523 somatic motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021532 neural tube patterning http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. http://purl.obolibrary.org/obo/GO_0021533 cell differentiation in hindbrain http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021534 cell proliferation in hindbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell that will reside in the hindbrain. http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development http://purl.obolibrary.org/obo/GO_0021675 nerve development The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021546 rhombomere development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021547 midbrain-hindbrain boundary initiation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021548 pons development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021550 medulla oblongata development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021551 central nervous system morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021555 midbrain-hindbrain boundary morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021556 central nervous system formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021559 trigeminal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021575 hindbrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021576 hindbrain formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021578 hindbrain maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021579 medulla oblongata morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021580 medulla oblongata formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021582 medulla oblongata maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021583 pons morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021584 pons formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021586 pons maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021593 rhombomere morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021594 rhombomere formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation http://purl.obolibrary.org/obo/GO_0021682 nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021626 central nervous system maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021635 trigeminal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021636 trigeminal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021638 trigeminal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021654 rhombomere boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021675 nerve development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021682 nerve maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0021703 locus ceruleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021704 locus ceruleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021705 locus ceruleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021706 locus ceruleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021718 superior olivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021719 superior olivary nucleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021720 superior olivary nucleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021722 superior olivary nucleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021732 midbrain-hindbrain boundary maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021753 superior salivary nucleus development http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021903 rostrocaudal neural tube patterning http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The process in which the neural tube is divided into specific regions along the rostrocaudal axis. http://purl.obolibrary.org/obo/GO_0021906 hindbrain-spinal cord boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. http://purl.obolibrary.org/obo/GO_0021990 neural plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0021999 neural plate anterior/posterior regionalization http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. http://purl.obolibrary.org/obo/GO_0022008 neurogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation Generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0022009 central nervous system vasculogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. http://purl.obolibrary.org/obo/GO_0022035 rhombomere cell migration http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. http://purl.obolibrary.org/obo/GO_0022037 metencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_0023019 signal transduction involved in regulation of gene expression http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. http://purl.obolibrary.org/obo/GO_0023052 signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. http://purl.obolibrary.org/obo/GO_0023061 signal release http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. http://purl.obolibrary.org/obo/GO_0030016 myofibril http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0030030 cell projection organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0030033 microvillus assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/GO_0030048 actin filament-based movement http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030050 vesicle transport along actin filament http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking Movement of a vesicle along an actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a peptide hormone from a cell. http://purl.obolibrary.org/obo/GO_0030073 insulin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. http://purl.obolibrary.org/obo/GO_0030133 transport vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. http://purl.obolibrary.org/obo/GO_0030199 collagen fibril organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030213 hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030214 hyaluronan catabolic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. http://purl.obolibrary.org/obo/GO_0030219 megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. http://purl.obolibrary.org/obo/GO_0030263 apoptotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation The compaction of chromatin during apoptosis. http://purl.obolibrary.org/obo/GO_0030264 nuclear fragmentation involved in apoptotic nuclear change http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA. http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0030279 negative regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0030307 positive regulation of cell growth http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030308 negative regulation of cell growth http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. http://purl.obolibrary.org/obo/GO_0030324 lung development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/GO_0030421 defecation http://purl.obolibrary.org/obo/GO_0022600 digestive system process The expulsion of feces from the rectum. http://purl.obolibrary.org/obo/GO_0030432 peristalsis http://purl.obolibrary.org/obo/GO_0014821 phasic smooth muscle contraction A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. http://purl.obolibrary.org/obo/GO_0030485 smooth muscle contractile fiber http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile fiber of smooth muscle cells. http://purl.obolibrary.org/obo/GO_0030573 bile acid catabolic process http://purl.obolibrary.org/obo/GO_0008206 bile acid metabolic process The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile. http://purl.obolibrary.org/obo/GO_0030642 intracellular sulfate ion homeostasis http://purl.obolibrary.org/obo/GO_0055063 sulfate ion homeostasis A homeostatic process involved in the maintenance of a steady state level of sulfate ions within a cell. http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle. http://purl.obolibrary.org/obo/GO_0030720 oocyte localization involved in germarium-derived egg chamber formation http://purl.obolibrary.org/obo/GO_0051674 localization of cell Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030901 midbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). http://purl.obolibrary.org/obo/GO_0030902 hindbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). http://purl.obolibrary.org/obo/GO_0030903 notochord development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/GO_0030917 midbrain-hindbrain boundary development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. http://purl.obolibrary.org/obo/GO_0031016 pancreas development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones. http://purl.obolibrary.org/obo/GO_0031017 exocrine pancreas development http://purl.obolibrary.org/obo/GO_0048732 gland development The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. http://purl.obolibrary.org/obo/GO_0031022 nuclear migration along microfilament http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0031045 dense core granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted. http://purl.obolibrary.org/obo/GO_0031076 embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. http://purl.obolibrary.org/obo/GO_0031112 positive regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. http://purl.obolibrary.org/obo/GO_0031115 negative regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031116 positive regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031117 positive regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of the plasma membrane surrounding the leading edge of a motile cell. http://purl.obolibrary.org/obo/GO_0031338 regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031339 negative regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031340 positive regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization http://purl.obolibrary.org/obo/GO_0051179 localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction http://purl.obolibrary.org/obo/GO_0045202 synapse The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that activates or increases the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031987 locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040011 locomotion Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0032024 positive regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/GO_0032057 negative regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032058 positive regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032059 bleb http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/GO_0032060 bleb assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a dense core granule. http://purl.obolibrary.org/obo/GO_0032231 regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032232 negative regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032233 positive regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032239 regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032240 negative regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032241 positive regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0032253 dense core granule localization http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0032272 negative regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032273 positive regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032331 negative regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032332 positive regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032364 intracellular oxygen homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of oxygen within a cell. http://purl.obolibrary.org/obo/GO_0032369 negative regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032370 positive regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032377 regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032378 negative regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032379 positive regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032409 regulation of transporter activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032410 negative regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops or reduces the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032411 positive regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032414 positive regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032412 regulation of monoatomic ion transmembrane transporter activity Any process that activates or increases the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032528 microvillus organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/GO_0032530 regulation of microvillus organization http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. http://purl.obolibrary.org/obo/GO_0032534 regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly A process that modulates the formation of a microvillus. http://purl.obolibrary.org/obo/GO_0032589 neuron projection membrane http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane The portion of the plasma membrane surrounding a neuron projection. http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from one location to another within a lipid bilayer. http://purl.obolibrary.org/obo/GO_0032790 ribosome disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/GO_0032868 response to insulin http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. http://purl.obolibrary.org/obo/GO_0032871 regulation of karyogamy http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032891 negative regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032892 positive regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a tissue. http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0032964 collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0032965 regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032966 negative regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032967 positive regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033033 negative regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033034 positive regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. http://purl.obolibrary.org/obo/GO_0033046 negative regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0033048 negative regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033059 cellular pigmentation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The deposition or aggregation of coloring matter in a cell. http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0033239 negative regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/GO_0033240 positive regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/GO_0033241 regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033242 negative regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033243 positive regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033278 cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle http://purl.obolibrary.org/obo/GO_0008104 protein localization A process in which a protein is transported to, or maintained in, a location within an organelle. http://purl.obolibrary.org/obo/GO_0033366 protein localization to secretory granule http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a secretory granule. http://purl.obolibrary.org/obo/GO_0033500 carbohydrate homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. http://purl.obolibrary.org/obo/GO_0033750 ribosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization A process in which a ribosome is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033762 response to glucagon http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. http://purl.obolibrary.org/obo/GO_0034067 protein localization to Golgi apparatus http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0034101 erythrocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis Any process of regulating the production and elimination of erythrocytes within an organism. http://purl.obolibrary.org/obo/GO_0034242 negative regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0034251 regulation of amide catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. http://purl.obolibrary.org/obo/GO_0034252 negative regulation of amide catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. http://purl.obolibrary.org/obo/GO_0034253 positive regulation of amide catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. http://purl.obolibrary.org/obo/GO_0034487 vacuolar amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport The process in which an amino acid is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034766 negative regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034767 positive regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035107 appendage morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. http://purl.obolibrary.org/obo/GO_0035270 endocrine system development http://purl.obolibrary.org/obo/GO_0048731 system development Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. http://purl.obolibrary.org/obo/GO_0035869 ciliary transition zone http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. http://purl.obolibrary.org/obo/GO_0036477 somatodendritic compartment http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. http://purl.obolibrary.org/obo/GO_0040011 locomotion http://purl.obolibrary.org/obo/GO_0008150 biological process Self-propelled movement of a cell or organism from one location to another. http://purl.obolibrary.org/obo/GO_0040020 regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. http://purl.obolibrary.org/obo/GO_0043025 neuronal cell body http://purl.obolibrary.org/obo/GO_0044297 cell body The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. http://purl.obolibrary.org/obo/GO_0043062 extracellular structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043233 organelle lumen http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/GO_0043473 pigmentation http://purl.obolibrary.org/obo/GO_0008150 biological process The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. http://purl.obolibrary.org/obo/GO_0043588 skin development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/GO_0044057 regulation of system process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044093 positive regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044782 cilium organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0045168 cell-cell signaling involved in cell fate commitment http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. http://purl.obolibrary.org/obo/GO_0045202 synapse http://purl.obolibrary.org/obo/GO_0030054 cell junction The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0045763 negative regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/GO_0045764 positive regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/GO_0045778 positive regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0045835 negative regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045836 positive regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045840 positive regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045927 positive regulation of growth http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045935 positive regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0046364 monosaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. http://purl.obolibrary.org/obo/GO_0046466 membrane lipid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane. http://purl.obolibrary.org/obo/GO_0046660 female sex differentiation http://purl.obolibrary.org/obo/GO_0007548 sex differentiation The establishment of the sex of a female organism by physical differentiation. http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0048483 autonomic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. http://purl.obolibrary.org/obo/GO_0048521 negative regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0048730 epidermis morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/GO_0048736 appendage development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. http://purl.obolibrary.org/obo/GO_0050714 positive regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0050796 regulation of insulin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of insulin. http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. http://purl.obolibrary.org/obo/GO_0051017 actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/GO_0051175 negative regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. http://purl.obolibrary.org/obo/GO_0051179 localization http://purl.obolibrary.org/obo/GO_0008150 biological process Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051647 nucleus localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051648 vesicle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization The directed movement of an organelle to a specific location. http://purl.obolibrary.org/obo/GO_0051668 localization within membrane http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. http://purl.obolibrary.org/obo/GO_0051674 localization of cell http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051875 pigment granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051904 pigment granule transport http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The directed movement of a pigment granule to a specific location. http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051961 negative regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051962 positive regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0051985 negative regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0055001 muscle cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. http://purl.obolibrary.org/obo/GO_0055057 neuroblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0055063 sulfate ion homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell. http://purl.obolibrary.org/obo/GO_0055080 monoatomic cation homeostasis http://purl.obolibrary.org/obo/GO_0050801 monoatomic ion homeostasis Any process involved in the maintenance of an internal steady state of monoatomic cations within an organism or cell. Monatomic cations (also called simple cations) are cations consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0055123 digestive system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0060142 regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0060143 positive regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0060170 ciliary membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a cilium. http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0061036 positive regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061458 reproductive system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. http://purl.obolibrary.org/obo/GO_0065010 extracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a substance from one side of an epithelium to the other. http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070664 negative regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070665 positive regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/GO_0071495 cellular response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the intracellular region. http://purl.obolibrary.org/obo/GO_0099501 exocytic vesicle membrane http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane The lipid bilayer surrounding an exocytic vesicle. http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The transport of organelles or other particles from one location in the cell to another along actin filaments. http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0099738 cell cortex region http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region The complete extent of cell cortex that underlies some some region of the plasma membrane. http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The chemical reactions and pathways involving insulin. http://purl.obolibrary.org/obo/GO_1901161 primary amino compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of primary amino compound. http://purl.obolibrary.org/obo/GO_1901652 response to peptide http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/GO_1901654 response to ketone http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound A response that results in a state of tolerance to ketone. http://purl.obolibrary.org/obo/GO_1901879 regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1901881 positive regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly Any process that activates or increases the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1902679 negative regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The disaggregation of an organelle into its constituent components. http://purl.obolibrary.org/obo/GO_1903115 regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nucleus organization. http://purl.obolibrary.org/obo/GO_1905268 negative regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905269 positive regulation of chromatin organization http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization Any process that activates or increases the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905332 positive regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905880 negative regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905881 positive regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1990351 transporter complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A macromolecular complex that contains both RNA and protein molecules. http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000649 regulation of sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032412 regulation of monoatomic ion transmembrane transporter activity Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_2000650 negative regulation of sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_2000651 positive regulation of sodium ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1902307 positive regulation of sodium ion transmembrane transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_0034330 cell junction organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. http://purl.obolibrary.org/obo/GO_0034349 glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system. http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034351 negative regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034352 positive regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034392 negative regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034393 positive regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034436 glycoprotein transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a solute is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034769 basement membrane disassembly http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion. http://purl.obolibrary.org/obo/GO_0035148 tube formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. http://purl.obolibrary.org/obo/GO_0035190 syncytial nuclear migration http://purl.obolibrary.org/obo/GO_0007097 nuclear migration The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisions and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. http://purl.obolibrary.org/obo/GO_0035234 ectopic germ cell programmed cell death http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. http://purl.obolibrary.org/obo/GO_0035260 internal genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. http://purl.obolibrary.org/obo/GO_0035261 external genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. http://purl.obolibrary.org/obo/GO_0035264 multicellular organism growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton A process in which a protein is transported to, or maintained at, a microtubule. http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location within the extracellular region. http://purl.obolibrary.org/obo/GO_0035622 intrahepatic bile duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver). http://purl.obolibrary.org/obo/GO_0035628 cystic duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gallbladder to the common bile duct. http://purl.obolibrary.org/obo/GO_0035645 enteric smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine. http://purl.obolibrary.org/obo/GO_0035735 intraciliary transport involved in cilium assembly http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. http://purl.obolibrary.org/obo/GO_0035736 cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_0035773 insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0030073 insulin secretion The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. http://purl.obolibrary.org/obo/GO_0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0035779 angioblast cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). http://purl.obolibrary.org/obo/GO_0035834 indole alkaloid metabolic process http://purl.obolibrary.org/obo/GO_0009820 alkaloid metabolic process The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton. http://purl.obolibrary.org/obo/GO_0035844 cloaca development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates. http://purl.obolibrary.org/obo/GO_0035855 megakaryocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell. http://purl.obolibrary.org/obo/GO_0035887 aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta. http://purl.obolibrary.org/obo/GO_0035904 aorta development http://purl.obolibrary.org/obo/GO_0060840 artery development The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0035905 ascending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035906 descending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035907 dorsal aorta development http://purl.obolibrary.org/obo/GO_0035904 aorta development The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0035910 ascending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035911 descending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035912 dorsal aorta morphogenesis http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell The regulated release of any steroid that acts as a hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0035935 androgen secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates. http://purl.obolibrary.org/obo/GO_0035992 tendon formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. http://purl.obolibrary.org/obo/GO_0036194 muscle cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/GO_0036195 muscle cell projection membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a muscle cell projection. http://purl.obolibrary.org/obo/GO_0036333 hepatocyte homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. http://purl.obolibrary.org/obo/GO_0036334 epidermal stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells. http://purl.obolibrary.org/obo/GO_0036342 post-anal tail morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. http://purl.obolibrary.org/obo/GO_0036504 Golgi membrane fusion http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. http://purl.obolibrary.org/obo/GO_0040015 negative regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040016 embryonic cleavage http://purl.obolibrary.org/obo/GO_0051301 cell division The first few specialized divisions of an activated animal egg. http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040018 positive regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040019 positive regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0040034 regulation of development, heterochronic http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached. http://purl.obolibrary.org/obo/GO_0042065 glial cell growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0042078 germ-line stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. http://purl.obolibrary.org/obo/GO_0042176 regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0042177 negative regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process. http://purl.obolibrary.org/obo/GO_0042415 norepinephrine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042421 norepinephrine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042422 norepinephrine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042428 serotonin metabolic process http://purl.obolibrary.org/obo/GO_0097164 ammonium ion metabolic process The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042429 serotonin catabolic process http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0042461 photoreceptor cell development Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. http://purl.obolibrary.org/obo/GO_0042478 regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042479 positive regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042480 negative regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042588 zymogen granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme. http://purl.obolibrary.org/obo/GO_0042589 zymogen granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a zymogen granule. http://purl.obolibrary.org/obo/GO_0042670 retinal cone cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. http://purl.obolibrary.org/obo/GO_0042996 regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0042997 negative regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0042998 positive regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0043001 Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0015031 protein transport The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. http://purl.obolibrary.org/obo/GO_0043133 hindgut contraction http://purl.obolibrary.org/obo/GO_0022600 digestive system process A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0043134 regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0043143 regulation of translation by machinery localization http://purl.obolibrary.org/obo/GO_0008104 protein localization Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0043264 extracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0043362 nucleate erythrocyte maturation http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus. http://purl.obolibrary.org/obo/GO_0043363 nucleate erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds. http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/GO_0043524 negative regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/GO_0043525 positive regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process. http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. http://purl.obolibrary.org/obo/GO_0043589 skin morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/GO_0043931 ossification involved in bone maturation http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0044062 regulation of excretion http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/GO_0044090 positive regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044207 translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/GO_0044258 intestinal lipid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas. http://purl.obolibrary.org/obo/GO_0044297 cell body http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. http://purl.obolibrary.org/obo/GO_0044342 type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin. http://purl.obolibrary.org/obo/GO_0044346 fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/GO_0045200 establishment of neuroblast polarity http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045600 positive regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045602 negative regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045603 positive regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045604 regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that modulates the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045605 negative regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045606 positive regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045647 negative regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045648 positive regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045653 negative regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045654 positive regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045662 negative regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045663 positive regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045719 negative regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070874 negative regulation of glycogen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/GO_0045721 negative regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. http://purl.obolibrary.org/obo/GO_0045722 positive regulation of gluconeogenesis http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process Any process that activates or increases the frequency, rate or extent of gluconeogenesis. http://purl.obolibrary.org/obo/GO_0045724 positive regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the formation of a cilium. http://purl.obolibrary.org/obo/GO_0045725 positive regulation of glycogen biosynthetic process http://purl.obolibrary.org/obo/GO_0070875 positive regulation of glycogen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. http://purl.obolibrary.org/obo/GO_0045732 positive regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0045734 regulation of acetate catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid. http://purl.obolibrary.org/obo/GO_0045753 negative regulation of acetate catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate. http://purl.obolibrary.org/obo/GO_0045754 positive regulation of acetate catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate. http://purl.obolibrary.org/obo/GO_0045759 negative regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045760 positive regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis Any process that activates or increases angiogenesis. http://purl.obolibrary.org/obo/GO_0045769 negative regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045770 positive regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046533 negative regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046534 positive regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046621 negative regulation of organ growth http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046622 positive regulation of organ growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0048103 somatic stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that activates, maintains or increases the rate of developmental growth. http://purl.obolibrary.org/obo/GO_0048770 pigment granule http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048823 nucleate erythrocyte development http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. http://purl.obolibrary.org/obo/GO_0050000 chromosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a chromosome is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of pigmented cell differentiation. http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051148 negative regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051149 positive regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051446 positive regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051447 negative regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051469 vesicle fusion with vacuole http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0051969 regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0055059 asymmetric neuroblast division http://purl.obolibrary.org/obo/GO_0055057 neuroblast division The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. http://purl.obolibrary.org/obo/GO_0060173 limb development http://purl.obolibrary.org/obo/GO_0048736 appendage development The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. http://purl.obolibrary.org/obo/GO_0060271 cilium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0060348 bone development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. http://purl.obolibrary.org/obo/GO_0060359 response to ammonium ion http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. http://purl.obolibrary.org/obo/GO_0060465 pharynx development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0060581 cell fate commitment involved in pattern specification http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. http://purl.obolibrary.org/obo/GO_0060840 artery development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. http://purl.obolibrary.org/obo/GO_0061009 common bile duct development http://purl.obolibrary.org/obo/GO_0035295 tube development The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gallbladder. The common bile duct transports bile from the liver and gallbladder to the intestine. http://purl.obolibrary.org/obo/GO_0061062 regulation of nematode larval development http://purl.obolibrary.org/obo/GO_0048580 regulation of post-embryonic development Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. http://purl.obolibrary.org/obo/GO_0061063 positive regulation of nematode larval development http://purl.obolibrary.org/obo/GO_0048582 positive regulation of post-embryonic development Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. http://purl.obolibrary.org/obo/GO_0061064 negative regulation of nematode larval development http://purl.obolibrary.org/obo/GO_0048581 negative regulation of post-embryonic development Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0050796 regulation of insulin secretion Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0061303 cornea development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. http://purl.obolibrary.org/obo/GO_0061469 regulation of type B pancreatic cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation. http://purl.obolibrary.org/obo/GO_0070874 negative regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0070875 positive regulation of glycogen metabolic process http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. http://purl.obolibrary.org/obo/GO_0070977 bone maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0071230 cellular response to amino acid stimulus http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0071242 cellular response to ammonium ion http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. http://purl.obolibrary.org/obo/GO_0071383 cellular response to steroid hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0071396 cellular response to lipid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0071418 cellular response to amine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0008104 protein localization Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. http://purl.obolibrary.org/obo/GO_0071711 basement membrane organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. http://purl.obolibrary.org/obo/GO_0071867 response to monoamine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane http://purl.obolibrary.org/obo/GO_0051668 localization within membrane A process in which a protein is transported to, or maintained in, a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. http://purl.obolibrary.org/obo/GO_0072697 protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, the cell cortex. http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0080154 regulation of fertilization http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0090162 establishment of epithelial cell polarity http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization of an epithelial cell. http://purl.obolibrary.org/obo/GO_0090168 Golgi reassembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090435 protein localization to nuclear envelope http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0097237 cellular response to toxic substance http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. http://purl.obolibrary.org/obo/GO_0097355 protein localization to heterochromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin. http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion http://purl.obolibrary.org/obo/GO_0048284 organelle fusion Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. http://purl.obolibrary.org/obo/GO_0098528 skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. http://purl.obolibrary.org/obo/GO_0098661 inorganic anion transmembrane transport http://purl.obolibrary.org/obo/GO_0098660 inorganic ion transmembrane transport The process in which an inorganic anion is transported across a membrane. http://purl.obolibrary.org/obo/GO_0098662 inorganic cation transmembrane transport http://purl.obolibrary.org/obo/GO_0098660 inorganic ion transmembrane transport A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0098751 bone cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The directed movement of a protein along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0099098 microtubule polymerization based movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The movement of a cellular component as a result of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0099632 protein transport within plasma membrane http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer A process in which protein is transported from one region of the plasma membrane to another. http://purl.obolibrary.org/obo/GO_1900116 extracellular negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction Any negative regulation of signal transduction that takes place in extracellular region. http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1901162 primary amino compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of primary amino compound. http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901457 regulation of response to acetate http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of response to acetate. http://purl.obolibrary.org/obo/GO_1901458 negative regulation of response to acetate http://purl.obolibrary.org/obo/GO_1901457 regulation of response to acetate Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate. http://purl.obolibrary.org/obo/GO_1901459 positive regulation of response to acetate http://purl.obolibrary.org/obo/GO_1901457 regulation of response to acetate Any process that activates or increases the frequency, rate or extent of response to acetate. http://purl.obolibrary.org/obo/GO_1901655 cellular response to ketone http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus. http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902913 positive regulation of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation. http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903225 negative regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903729 regulation of plasma membrane organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of plasma membrane organization. http://purl.obolibrary.org/obo/GO_1903778 protein localization to vacuolar membrane http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. http://purl.obolibrary.org/obo/GO_1904018 positive regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that activates or increases the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1904063 negative regulation of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_1904064 positive regulation of cation transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that activates or increases the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_1905690 nucleus disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a nucleus into its constituent components. http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1905771 negative regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0008104 protein localization A process in which a protein is transported to, or maintained in, the cell periphery. http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000384 negative regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000542 negative regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086015 SA node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a sinoatrial node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086016 AV node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in an atrioventricular node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086017 Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a Purkinje myocyte. http://purl.obolibrary.org/obo/GO_0086018 SA node cell to atrial cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte. http://purl.obolibrary.org/obo/GO_0086019 cell-cell signaling involved in cardiac conduction http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium. http://purl.obolibrary.org/obo/GO_0086027 AV node cell to bundle of His cell signaling http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte. http://purl.obolibrary.org/obo/GO_0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction http://purl.obolibrary.org/obo/GO_0007154 cell communication Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0090063 positive regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090070 positive regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090071 negative regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090091 positive regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0090166 Golgi disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0090170 regulation of Golgi inheritance http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0090274 positive regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0090275 negative regulation of somatostatin secretion http://purl.obolibrary.org/obo/GO_0090273 regulation of somatostatin secretion Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0090299 regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090300 positive regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090301 negative regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090326 positive regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090327 negative regulation of locomotion involved in locomotory behavior http://purl.obolibrary.org/obo/GO_0090325 regulation of locomotion involved in locomotory behavior Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. http://purl.obolibrary.org/obo/GO_0090685 RNA localization to nucleus http://purl.obolibrary.org/obo/GO_0006403 RNA localization A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. http://purl.obolibrary.org/obo/GO_0097049 motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0097050 type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0097254 renal tubular secretion http://purl.obolibrary.org/obo/GO_0003014 renal system process The elimination of substances from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs. http://purl.obolibrary.org/obo/GO_0097272 ammonium homeostasis http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis Any biological process involved in the maintenance of an internal steady state of ammonium. http://purl.obolibrary.org/obo/GO_0097275 intracellular ammonium homeostasis http://purl.obolibrary.org/obo/GO_0097272 ammonium homeostasis A homeostatic process involved in the maintenance of a steady state level of ammonium within a cell. http://purl.obolibrary.org/obo/GO_0097284 hepatocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a hepatocyte, the main structural component of the liver. http://purl.obolibrary.org/obo/GO_0097386 glial cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a glial cell. http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An arrangement of closely apposed microtubules running parallel to each other. http://purl.obolibrary.org/obo/GO_0097473 retinal rod cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0097474 retinal cone cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0097512 cardiac myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/GO_0097711 ciliary basal body-plasma membrane docking http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. http://purl.obolibrary.org/obo/GO_0098523 neuromuscular junction of myotube http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction A neuromuscular junction in which the target muscle cell is a myotube. http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A complex of collagen trimers such as a fibril or collagen network. http://purl.obolibrary.org/obo/GO_0098660 inorganic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which an inorganic ion is transported across a membrane. http://purl.obolibrary.org/obo/GO_0098723 skeletal muscle myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A myofibril of a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_0098867 intramembranous bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/GO_0098871 postsynaptic actin cytoskeleton http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton The actin cytoskeleton that is part of a postsynapse. http://purl.obolibrary.org/obo/GO_0098883 synapse pruning http://purl.obolibrary.org/obo/GO_0050808 synapse organization A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared. http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098906 regulation of Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098907 regulation of SA node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098908 regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098917 retrograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0098920 retrograde trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand. http://purl.obolibrary.org/obo/GO_0098926 postsynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a postsynapse. http://purl.obolibrary.org/obo/GO_0098928 presynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a presynapse. http://purl.obolibrary.org/obo/GO_0098974 postsynaptic actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0098975 postsynapse of neuromuscular junction http://purl.obolibrary.org/obo/GO_0098794 postsynapse The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma. http://purl.obolibrary.org/obo/GO_0098981 cholinergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses acetylcholine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0098992 neuronal dense core vesicle http://purl.obolibrary.org/obo/GO_0031045 dense core granule A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals. http://purl.obolibrary.org/obo/GO_0099012 neuronal dense core vesicle membrane http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane The lipid bilayer surrounding a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0099014 neuronal dense core vesicle organization http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0099054 presynapse assembly http://purl.obolibrary.org/obo/GO_0099172 presynapse organization The aggregation, arrangement and bonding together of a set of components to form a presynapse. http://purl.obolibrary.org/obo/GO_0099068 postsynapse assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a postsynapse. http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A polymeric supramolecular structure. http://purl.obolibrary.org/obo/GO_0099082 retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099083 retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099112 microtubule polymerization based protein transport http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The transport of a protein driven by polymerization of a microtubule to which it is attached. http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport A microtubule-based process that results in the transport of proteins. http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling to, from or within a synapse. http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling in either direction across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling to or from a synapse, mediated by a peptide. http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid. http://purl.obolibrary.org/obo/GO_0099546 protein catabolic process, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission. http://purl.obolibrary.org/obo/GO_0099547 regulation of translation at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the synapse. http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099552 trans-synaptic signaling by lipid, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the postsynapse. http://purl.obolibrary.org/obo/GO_0099574 regulation of protein catabolic process at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating protein degradation at the synapse. http://purl.obolibrary.org/obo/GO_0099575 regulation of protein catabolic process at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. http://purl.obolibrary.org/obo/GO_0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. http://purl.obolibrary.org/obo/GO_0099577 regulation of translation at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. http://purl.obolibrary.org/obo/GO_0099578 regulation of translation at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. http://purl.obolibrary.org/obo/GO_0099640 axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule The directed movement of proteins along microtubules in neuron projections. http://purl.obolibrary.org/obo/GO_0101023 vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0101024 mitotic nuclear membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis. http://purl.obolibrary.org/obo/GO_0101025 nuclear membrane biogenesis http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis The process in which a nuclear membrane is synthesized, aggregates, and bonds together. http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any regulation of signal transduction that takes place in the extracellular region. http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900118 negative regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900119 positive regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900125 regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900126 negative regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900127 positive regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900193 regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900194 negative regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900195 positive regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1901143 insulin catabolic process http://purl.obolibrary.org/obo/GO_1901142 insulin metabolic process The chemical reactions and pathways resulting in the breakdown of insulin. http://purl.obolibrary.org/obo/GO_1901148 gene expression involved in extracellular matrix organization http://purl.obolibrary.org/obo/GO_0010467 gene expression Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901191 negative regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901192 positive regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901202 negative regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901203 positive regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901211 negative regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901212 positive regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901220 negative regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901401 regulation of tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process. http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1903011 negative regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that stops, prevents or reduces the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903012 positive regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that activates or increases the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903076 regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903336 negative regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903337 positive regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that activates or increases the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of Golgi organization. http://purl.obolibrary.org/obo/GO_1903441 protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/GO_1903831 signal transduction involved in cellular response to ammonium ion http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any signal transduction that is involved in cellular response to ammonium ion. http://purl.obolibrary.org/obo/GO_1904587 response to glycoprotein http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. http://purl.obolibrary.org/obo/GO_1905038 regulation of membrane lipid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of membrane lipid metabolic process. http://purl.obolibrary.org/obo/GO_1905383 protein localization to presynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse A process in which a protein is transported to, or maintained in, a location within a presynapse. http://purl.obolibrary.org/obo/GO_1905475 regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1905476 negative regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1905477 positive regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_1905475 regulation of protein localization to membrane Any process that activates or increases the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1990182 exosomal secretion http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_2000282 regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000283 negative regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000284 positive regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000381 negative regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000382 positive regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that activates or increases the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001234 negative regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001235 positive regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1901402 negative regulation of tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process. http://purl.obolibrary.org/obo/GO_1901403 positive regulation of tetrapyrrole metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process. http://purl.obolibrary.org/obo/GO_1901405 negative regulation of tetrapyrrole catabolic process http://purl.obolibrary.org/obo/GO_1901404 regulation of tetrapyrrole catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process. http://purl.obolibrary.org/obo/GO_1901406 positive regulation of tetrapyrrole catabolic process http://purl.obolibrary.org/obo/GO_1901404 regulation of tetrapyrrole catabolic process Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process. http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901550 regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901551 negative regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901552 positive regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901609 negative regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901610 positive regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901693 negative regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901706 mesenchymal cell differentiation involved in bone development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_1901964 positive regulation of cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1901963 regulation of cell proliferation involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902018 negative regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902034 negative regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902035 positive regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902037 negative regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902038 positive regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902074 response to salt http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus. http://purl.obolibrary.org/obo/GO_1902075 cellular response to salt http://purl.obolibrary.org/obo/GO_1902074 response to salt Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus. http://purl.obolibrary.org/obo/GO_1902217 erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process Any apoptotic process in an erythrocyte. http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902251 negative regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902252 positive regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902256 regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902257 negative regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902258 positive regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902339 positive regulation of apoptotic process involved in morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902262 apoptotic process involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that is involved in blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_1902305 regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902306 negative regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0010766 negative regulation of sodium ion transport Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902307 positive regulation of sodium ion transmembrane transport http://purl.obolibrary.org/obo/GO_0010765 positive regulation of sodium ion transport Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport. http://purl.obolibrary.org/obo/GO_1902340 negative regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1902463 protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0008104 protein localization A process in which a protein is transported to, or maintained in, a location within a cell leading edge. http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_1902474 positive regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_1902488 cholangiocyte apoptotic process http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process Any apoptotic process in a cholangiocyte. http://purl.obolibrary.org/obo/GO_1902489 hepatoblast apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a hepatoblast. http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of organelle transport along microtubule. http://purl.obolibrary.org/obo/GO_1902570 protein localization to nucleolus http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained in, a location within a nucleolus. http://purl.obolibrary.org/obo/GO_1902738 regulation of chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_1902761 positive regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that activates or increases the frequency, rate or extent of chondrocyte development. http://purl.obolibrary.org/obo/GO_1902809 regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902810 negative regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902811 positive regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902816 regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1902817 negative regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902839 negative regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902840 positive regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902864 negative regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902865 positive regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1903116 positive regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/GO_1903120 protein localization to actin filament bundle http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. http://purl.obolibrary.org/obo/GO_1903226 positive regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903292 protein localization to Golgi membrane http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. http://purl.obolibrary.org/obo/GO_1903379 regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that modulates the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903380 positive regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903412 response to bile acid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. http://purl.obolibrary.org/obo/GO_1903413 cellular response to bile acid http://purl.obolibrary.org/obo/GO_1903412 response to bile acid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. http://purl.obolibrary.org/obo/GO_1903537 meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process Any meiotic cell cycle process that is involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903538 regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis Any process that modulates the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903542 negative regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903543 positive regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903551 regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903552 negative regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903553 positive regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903565 negative regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903566 positive regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium Any process that activates or increases the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903567 regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903568 negative regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903569 positive regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903780 negative regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903781 positive regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that activates or increases the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903795 regulation of inorganic anion transmembrane transport http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport. http://purl.obolibrary.org/obo/GO_1903796 negative regulation of inorganic anion transmembrane transport http://purl.obolibrary.org/obo/GO_1903795 regulation of inorganic anion transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport. http://purl.obolibrary.org/obo/GO_1903797 positive regulation of inorganic anion transmembrane transport http://purl.obolibrary.org/obo/GO_1903795 regulation of inorganic anion transmembrane transport Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport. http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904491 protein localization to ciliary transition zone http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1905755 protein localization to cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. http://purl.obolibrary.org/obo/GO_1905821 positive regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1990010 compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1990009 retinal cell apoptotic process Any apoptotic process in a compound eye retinal cell. http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001015 negative regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001016 positive regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1905720 cytoplasmic microtubule bundle http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle Any microtubule bundle that is part of a cytoplasm. http://purl.obolibrary.org/obo/GO_1905806 regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905807 negative regulation of synapse pruning http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905808 positive regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905833 negative regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905872 negative regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905873 positive regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905900 negative regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905901 positive regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905903 negative regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905904 positive regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that activates or increases the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905921 regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905922 negative regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060410 negative regulation of acetylcholine metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905923 positive regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905937 negative regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905938 positive regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation Any process that activates or increases the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905940 negative regulation of gonad development http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905941 positive regulation of gonad development http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1990280 RNA localization to chromatin http://purl.obolibrary.org/obo/GO_0006403 RNA localization A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_1990502 dense core granule maturation http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis. http://purl.obolibrary.org/obo/GO_1990849 vacuolar localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_1990917 ooplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of an ovum. http://purl.obolibrary.org/obo/GO_2000074 regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_2000077 negative regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_2000078 positive regulation of type B pancreatic cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of pancreatic B cell development. http://purl.obolibrary.org/obo/GO_2000173 negative regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development Any process that modulates the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000195 negative regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000196 positive regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that activates or increases the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_2000227 negative regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_2000228 positive regulation of pancreatic A cell differentiation http://purl.obolibrary.org/obo/GO_2000226 regulation of pancreatic A cell differentiation Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation. http://purl.obolibrary.org/obo/GO_2000248 negative regulation of establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000270 negative regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000271 positive regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000287 positive regulation of myotome development http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development Any process that activates or increases the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_2000288 positive regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that activates or increases the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000292 regulation of defecation http://purl.obolibrary.org/obo/GO_0044062 regulation of excretion Any process that modulates the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_2000293 negative regulation of defecation http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that stops, prevents or reduces the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_2000294 positive regulation of defecation http://purl.obolibrary.org/obo/GO_2000292 regulation of defecation Any process that activates or increases the frequency, rate or extent of defecation. http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000352 negative regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000353 positive regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000374 regulation of oxygen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of oxygen metabolic process. http://purl.obolibrary.org/obo/GO_2000375 negative regulation of oxygen metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process. http://purl.obolibrary.org/obo/GO_2000376 positive regulation of oxygen metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of oxygen metabolic process. http://purl.obolibrary.org/obo/GO_2000385 positive regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that activates or increases the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000496 negative regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000497 positive regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that modulates the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000672 negative regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000673 positive regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000675 negative regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000676 positive regulation of type B pancreatic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000674 regulation of type B pancreatic cell apoptotic process Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000691 negative regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000700 positive regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000790 regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_2000791 negative regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_2000792 positive regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_2000790 regulation of mesenchymal cell proliferation involved in lung development Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/GO_2000818 negative regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000835 negative regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000836 positive regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that activates or increases the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/GO_2001213 negative regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/GO_2001214 positive regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/PR_000001002 CD19 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction. http://purl.obolibrary.org/obo/PR_000001003 CD34 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain http://purl.obolibrary.org/obo/PR_000025796 integrin alpha An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000001012 integrin alpha-M http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. http://purl.obolibrary.org/obo/PR_000001020 CD3 epsilon http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration. http://purl.obolibrary.org/obo/PR_000001024 neural cell adhesion molecule 1 http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001083 CD2 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain. http://purl.obolibrary.org/obo/PR_000001289 membrane-spanning 4-domains subfamily A member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001327 cadherin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. http://purl.obolibrary.org/obo/PR_000001444 cadherin-5 http://purl.obolibrary.org/obo/PR_000001327 cadherin A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001839 T-cell surface glycoprotein CD5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001869 interleukin-7 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001889 CD14 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001945 transferrin receptor protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain. http://purl.obolibrary.org/obo/PR_000002112 vascular endothelial growth factor receptor 2 http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is the translation product of any of the LY6 genes (LY6A-LY6I). http://purl.obolibrary.org/obo/PR_000002978 lymphocyte antigen 6G http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002981 lymphocyte antigen 76 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A protein that is a translation product of the Ly76 gene in mouse. http://purl.obolibrary.org/obo/PR_000018263 amino acid chain http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. http://purl.obolibrary.org/obo/PR_000025796 integrin alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif. http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is encoded in the genome of some Eukaryota. http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is encoded in the genome of Mus musculus. http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is encoded in the genome of Homo sapiens. http://purl.obolibrary.org/obo/PR_P11215 integrin alpha-M (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein An integrin alpha-M that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P01732 T-cell surface glycoprotein CD8 alpha chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P02786 transferrin receptor protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A transferrin receptor protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P06729 T-cell surface antigen CD2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD2 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P07766 T-cell surface glycoprotein CD3 epsilon chain (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD3 epsilon that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P15391 B-lymphocyte antigen CD19 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A CD19 molecule that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P17542 T-cell acute lymphocytic leukemia protein 1 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P22091 T-cell acute lymphocytic leukemia protein 1 homolog (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P33151 cadherin-5 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A cadherin-5 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P35968 vascular endothelial growth factor receptor 2 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A vascular endothelial growth factor receptor 2 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P16872 interleukin-7 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P19437 B-lymphocyte antigen CD20 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22646 T-cell surface glycoprotein CD3 epsilon chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD3 epsilon that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55075 fibroblast growth factor 8 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A fibroblast growth factor 8 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P55284 cadherin-5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cadherin-5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q15465 sonic hedgehog protein (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A sonic hedgehog protein that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_Q62351 transferrin receptor protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transferrin receptor protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q64314 hematopoietic progenitor cell antigen CD34 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD34 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/RO_0002577 system http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity consisting of multiple components that are causally integrated. http://purl.obolibrary.org/obo/CL_0008024 pancreatic endocrine cell http://purl.obolibrary.org/obo/CL_0000164 enteroendocrine cell An endocrine cell that is part of the pancreas. http://purl.obolibrary.org/obo/CL_0011115 precursor cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that, by division or terminal differentiation, can give rise to other cell types. http://purl.obolibrary.org/obo/NBO_0000073 chewing http://purl.obolibrary.org/obo/NBO_0000747 jaw movement The act of repeated grinding, tearing, and or crushing with teeth or jaws [NBO:SMAC] http://purl.obolibrary.org/obo/GO_0140029 exocytic process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular processes that contribute to exocytosis. http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0099172 presynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse. http://purl.obolibrary.org/obo/GO_0099175 regulation of postsynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a postsynapse. http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. http://purl.obolibrary.org/obo/GO_0062149 detection of stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/UBERON_0039222 cystic artery http://purl.obolibrary.org/obo/UBERON_0015796 liver blood vessel An artery that supplies oxygenated blood to the cystic duct. http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components. http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes. http://purl.obolibrary.org/obo/PATO_0070047 polychromatophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/PATO_0040072 high nuclear/cytoplasmic ratio http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. http://purl.obolibrary.org/obo/GO_0008219 cell death http://purl.obolibrary.org/obo/GO_0009987 cellular process Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008292 acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_1900620 acetate ester biosynthetic process The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity Enables the transfer of a protein from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008544 epidermis development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/GO_0008594 photoreceptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0008645 hexose transmembrane transport http://purl.obolibrary.org/obo/GO_0015749 monosaccharide transmembrane transport The process in which hexose is transported across a membrane. Hexoses are aldoses with a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/GO_0009056 catabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009314 response to radiation http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. http://purl.obolibrary.org/obo/GO_0009581 detection of external stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus. http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0009725 response to hormone http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/GO_0009746 response to hexose http://purl.obolibrary.org/obo/GO_0034284 response to monosaccharide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. http://purl.obolibrary.org/obo/GO_0009749 response to glucose http://purl.obolibrary.org/obo/GO_0009746 response to hexose Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0009790 embryo development http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/GO_0009821 alkaloid biosynthetic process http://purl.obolibrary.org/obo/GO_0044550 secondary metabolite biosynthetic process The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases). http://purl.obolibrary.org/obo/GO_0009822 alkaloid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009994 oocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. http://purl.obolibrary.org/obo/GO_0010032 meiotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation Compaction of chromatin structure prior to meiosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0010034 response to acetate http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus. http://purl.obolibrary.org/obo/GO_0010038 response to metal ion http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. http://purl.obolibrary.org/obo/GO_0010070 zygote asymmetric cell division http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. http://purl.obolibrary.org/obo/GO_0010171 body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the soma are generated and organized. http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010455 positive regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. http://purl.obolibrary.org/obo/GO_0010481 epidermal cell division http://purl.obolibrary.org/obo/GO_0051301 cell division Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. http://purl.obolibrary.org/obo/GO_0010482 regulation of epidermal cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. http://purl.obolibrary.org/obo/GO_0010496 intercellular transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The movement of substances between cells. http://purl.obolibrary.org/obo/GO_0010549 regulation of membrane disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane disassembly. http://purl.obolibrary.org/obo/GO_0010559 regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010567 regulation of ketone catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0010611 regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010612 regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010613 positive regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010614 negative regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010615 positive regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010616 negative regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The activation of endogenous cellular processes that result in the death of a cell as part of its development. http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations. http://purl.obolibrary.org/obo/GO_0010659 cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010663 positive regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010664 negative regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010666 positive regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010667 negative regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010700 negative regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0010701 positive regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0010710 regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010711 negative regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010716 negative regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010765 positive regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010766 negative regulation of sodium ion transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010770 positive regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/GO_0010771 negative regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010828 positive regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport Any process that increases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010829 negative regulation of D-glucose transmembrane transport http://purl.obolibrary.org/obo/GO_0010827 regulation of D-glucose transmembrane transport Any process that decreases the frequency, rate or extent of glucose transport across a membrane. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010842 retina layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. http://purl.obolibrary.org/obo/GO_0010893 positive regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0010907 positive regulation of glucose metabolic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. http://purl.obolibrary.org/obo/GO_0010937 regulation of cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule depolymerization Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0010938 cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer surrounding any membrane-bounded vesicle in the cell. http://purl.obolibrary.org/obo/GO_0014009 glial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014014 negative regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014015 positive regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014016 neuroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. http://purl.obolibrary.org/obo/GO_0014019 neuroblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. http://purl.obolibrary.org/obo/GO_0014023 neural rod formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014025 neural keel formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014028 notochord formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. http://purl.obolibrary.org/obo/GO_0014029 neural crest formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0014031 mesenchymal cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. http://purl.obolibrary.org/obo/GO_0014041 regulation of neuron maturation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. http://purl.obolibrary.org/obo/GO_0014042 positive regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation Any process that activates or increases the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014043 negative regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014055 acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS). http://purl.obolibrary.org/obo/GO_0014056 regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014057 positive regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014058 negative regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014061 regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0014062 regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014063 negative regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014064 positive regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014733 regulation of skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014734 skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process Any process that modulates the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014807 regulation of somitogenesis http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of somitogenesis. http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006942 regulation of striated muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction. http://purl.obolibrary.org/obo/GO_0014821 phasic smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. http://purl.obolibrary.org/obo/GO_0014827 intestine smooth muscle contraction http://purl.obolibrary.org/obo/GO_0014831 gastro-intestinal system smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. http://purl.obolibrary.org/obo/GO_0014831 gastro-intestinal system smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). http://purl.obolibrary.org/obo/GO_0014852 regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system. http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0014856 skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014858 positive regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014859 negative regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014860 neurotransmitter secretion involved in regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. http://purl.obolibrary.org/obo/GO_0014861 regulation of skeletal muscle contraction via regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes. http://purl.obolibrary.org/obo/GO_0014866 skeletal myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. http://purl.obolibrary.org/obo/GO_0014872 myoblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0014874 response to stimulus involved in regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014878 response to electrical stimulus involved in regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014879 detection of electrical stimulus involved in regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0050981 detection of electrical stimulus The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014887 cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014895 smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/GO_0014904 myotube cell development http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0015101 organic cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015106 bicarbonate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008514 organic anion transmembrane transporter activity Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-. http://purl.obolibrary.org/obo/GO_0015123 acetate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0008028 monocarboxylic acid transmembrane transporter activity Enables the transfer of acetate from one side of a membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid. http://purl.obolibrary.org/obo/GO_0015125 bile acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity Enables the transfer of bile acid from one side of a membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. http://purl.obolibrary.org/obo/GO_0015127 bilirubin transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005310 dicarboxylic acid transmembrane transporter activity Enables the transfer of bilirubin from one side of a membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile. http://purl.obolibrary.org/obo/GO_0015144 carbohydrate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carbohydrate from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015145 monosaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051119 sugar transmembrane transporter activity Enables the transfer of a monosaccharide from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015159 polysaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0015318 inorganic molecular entity transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an inorganic molecular entity from the outside of a cell to the inside of the cell across a membrane. An inorganic molecular entity is a molecular entity that contains no carbon. http://purl.obolibrary.org/obo/GO_0015669 gas transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015695 organic cation transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015701 bicarbonate transport http://purl.obolibrary.org/obo/GO_0015711 organic anion transport The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015721 bile acid and bile salt transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015723 bilirubin transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015749 monosaccharide transmembrane transport http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport The process in which a monosaccharide is transported across a lipid bilayer, from one side of a membrane to the other. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. http://purl.obolibrary.org/obo/GO_0015774 polysaccharide transport http://purl.obolibrary.org/obo/GO_0008643 carbohydrate transport The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0015849 organic acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0015874 norepinephrine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0016057 regulation of membrane potential in photoreceptor cell http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon. http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0016321 female meiosis chromosome segregation http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0016528 sarcoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0017085 response to insecticide http://purl.obolibrary.org/obo/GO_0009636 response to toxic substance Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects. http://purl.obolibrary.org/obo/GO_0017126 nucleologenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. http://purl.obolibrary.org/obo/GO_0017145 stem cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0019755 one-carbon compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0019867 outer membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. http://purl.obolibrary.org/obo/GO_0021782 glial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0022406 membrane docking http://purl.obolibrary.org/obo/GO_0009987 cellular process The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a macromolecule from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0022890 inorganic cation transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015318 inorganic molecular entity transmembrane transporter activity Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly Formation of myofibrils, the repeating units of striated muscle. http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly http://purl.obolibrary.org/obo/GO_0061024 membrane organization The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. http://purl.obolibrary.org/obo/GO_0030574 collagen catabolic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a transport vesicle. http://purl.obolibrary.org/obo/GO_0030660 Golgi-associated vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. http://purl.obolibrary.org/obo/GO_0030951 establishment or maintenance of microtubule cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organization http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. http://purl.obolibrary.org/obo/GO_0031090 organelle membrane http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization Any process that modulates the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031982 vesicle http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle Any small, fluid-filled, spherical organelle enclosed by membrane. http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032223 negative regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032224 positive regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032412 regulation of monoatomic ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity Any process that modulates the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0032412 regulation of monoatomic ion transmembrane transporter activity Any process that stops or reduces the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032782 bile acid secretion http://purl.obolibrary.org/obo/GO_0046717 acid secretion The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0032869 cellular response to insulin stimulus http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus http://purl.obolibrary.org/obo/GO_0009725 response to hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0032879 regulation of localization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a muscle cell population by cell division. http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/GO_0033993 response to lipid http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a carbohydrate is transported across a membrane. http://purl.obolibrary.org/obo/GO_0034220 monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0034284 response to monosaccharide http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0035835 indole alkaloid biosynthetic process http://purl.obolibrary.org/obo/GO_0009821 alkaloid biosynthetic process The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton. http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/GO_0042063 gliogenesis http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042551 neuron maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur. http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043200 response to amino acid http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043279 response to alkaloid http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms http://purl.obolibrary.org/obo/GO_0008150 biological process Any process evolved to enable an interaction with an organism of a different species. http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers. http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0045733 acetate catabolic process http://purl.obolibrary.org/obo/GO_0072329 monocarboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid. http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that modulates the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0045939 negative regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0045940 positive regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0045988 negative regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045932 negative regulation of muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0045989 positive regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045933 positive regulation of muscle contraction Any process that activates or increases the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0046112 nucleobase biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0046467 membrane lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. http://purl.obolibrary.org/obo/GO_0046545 development of primary female sexual characteristics http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0046873 metal ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022890 inorganic cation transmembrane transporter activity Enables the transfer of metal ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0046929 negative regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0048570 notochord morphogenesis http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/GO_0048581 negative regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048582 positive regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048628 myoblast maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/GO_0048635 negative regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/GO_0048636 positive regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that activates, maintains or increases the rate of muscle development. http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0048864 stem cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any biological process involved in the maintenance of an internal steady state of a chemical. http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. http://purl.obolibrary.org/obo/GO_0050981 detection of electrical stimulus http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus The series of events by which an electrical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0050995 negative regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0050996 positive regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0051049 regulation of transport http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051176 positive regulation of sulfur metabolic process http://purl.obolibrary.org/obo/GO_0042762 regulation of sulfur metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur. http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051602 response to electrical stimulus http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0051640 organelle localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which an organelle is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0055088 lipid homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060042 retina morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the retina is generated and organized. http://purl.obolibrary.org/obo/GO_0060048 cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction Muscle contraction of cardiac muscle tissue. http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060252 positive regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that activates or increases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060253 negative regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that stops or decreases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. http://purl.obolibrary.org/obo/GO_0060491 regulation of cell projection assembly http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the rate, frequency, or extent of cell projection assembly. http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport The regulated release of acetylcholine by a cell. http://purl.obolibrary.org/obo/GO_0061687 detoxification of inorganic compound http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds. http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0070727 cellular macromolecule localization http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. http://purl.obolibrary.org/obo/GO_0071322 cellular response to carbohydrate stimulus http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/GO_0071331 cellular response to hexose stimulus http://purl.obolibrary.org/obo/GO_0071326 cellular response to monosaccharide stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. http://purl.obolibrary.org/obo/GO_0071333 cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0071331 cellular response to hexose stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a protein is transported across a membrane. http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis http://purl.obolibrary.org/obo/GO_0009987 cellular process A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0072488 ammonium transmembrane transport http://purl.obolibrary.org/obo/GO_0098662 inorganic cation transmembrane transport The process in which ammonium is transported across a membrane. Ammonium is the cation NH4+. http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization The aggregation, arrangement and bonding together of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is a (regional) part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098655 monoatomic cation transmembrane transport http://purl.obolibrary.org/obo/GO_0034220 monoatomic ion transmembrane transport The process in which a monoatomic cation is transported across a membrane. Monatomic cations (also called simple cations) are positively charged ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. http://purl.obolibrary.org/obo/GO_0098754 detoxification http://purl.obolibrary.org/obo/GO_0008150 biological process Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Any vesicle-mediated transport that occurs in a synapse. http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport http://purl.obolibrary.org/obo/GO_0006810 transport A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0100001 regulation of skeletal muscle contraction by action potential http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any action potential process that regulates skeletal muscle contraction. http://purl.obolibrary.org/obo/GO_1900376 regulation of secondary metabolite biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process. http://purl.obolibrary.org/obo/GO_1900378 positive regulation of secondary metabolite biosynthetic process http://purl.obolibrary.org/obo/GO_1900376 regulation of secondary metabolite biosynthetic process Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process. http://purl.obolibrary.org/obo/GO_1900619 acetate ester metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid. http://purl.obolibrary.org/obo/GO_1900620 acetate ester biosynthetic process http://purl.obolibrary.org/obo/GO_1900619 acetate ester metabolic process The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid. http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901404 regulation of tetrapyrrole catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process. http://purl.obolibrary.org/obo/GO_1901463 regulation of tetrapyrrole biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process. http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_1901702 salt transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of salt from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902358 sulfate transmembrane transport http://purl.obolibrary.org/obo/GO_0098661 inorganic anion transmembrane transport The directed movement of sulfate across a membrane. http://purl.obolibrary.org/obo/GO_1902495 transmembrane transporter complex http://purl.obolibrary.org/obo/GO_1990351 transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902532 negative regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902533 positive regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/GO_1904062 regulation of monoatomic cation transmembrane transport http://purl.obolibrary.org/obo/GO_0034765 regulation of monoatomic ion transmembrane transport Any process that modulates the frequency, rate or extent of cation transmembrane transport. http://purl.obolibrary.org/obo/GO_1904396 regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904680 peptide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that activates or increases the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_0051970 negative regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0051971 positive regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0055003 cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/GO_0055009 atrial cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structure of cardiac atrium muscle is generated and organized. http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055019 negative regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055020 positive regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that modulates the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055022 negative regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055023 positive regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055025 positive regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055026 negative regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055056 D-glucose transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015149 hexose transmembrane transporter activity Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0055107 Golgi to secretory granule transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex. http://purl.obolibrary.org/obo/GO_0055108 Golgi to transport vesicle transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. http://purl.obolibrary.org/obo/GO_0055118 negative regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060021 roof of mouth development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. http://purl.obolibrary.org/obo/GO_0060037 pharyngeal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. http://purl.obolibrary.org/obo/GO_0060038 cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The expansion of a cardiac muscle cell population by cell division. http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060044 negative regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060045 positive regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060096 serotonin secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0060214 endocardium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0060218 hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0060221 retinal rod cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0110020 regulation of actomyosin structure organization Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060298 positive regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060299 negative regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060323 head morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/GO_0060324 face development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. http://purl.obolibrary.org/obo/GO_0060325 face morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. http://purl.obolibrary.org/obo/GO_0060343 trabecula formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/GO_0060344 liver trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/GO_0060345 spleen trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/GO_0060347 heart trabecula formation http://purl.obolibrary.org/obo/GO_0060343 trabecula formation The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod. http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which bones are generated and organized. http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0060410 negative regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0060414 aorta smooth muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060426 lung vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. http://purl.obolibrary.org/obo/GO_0060427 lung connective tissue development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. http://purl.obolibrary.org/obo/GO_0060428 lung epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. http://purl.obolibrary.org/obo/GO_0060431 primary lung bud formation http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. http://purl.obolibrary.org/obo/GO_0060433 bronchus development http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060434 bronchus morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060437 lung growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/GO_0060438 trachea development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060439 trachea morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060440 trachea formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060441 epithelial tube branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0060450 positive regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0043134 regulation of hindgut contraction Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0060451 negative regulation of hindgut contraction http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. http://purl.obolibrary.org/obo/GO_0060452 positive regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that increases the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060453 regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0060454 positive regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0060453 regulation of gastric acid secretion Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0060455 negative regulation of gastric acid secretion http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0060458 right lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/GO_0060459 left lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/GO_0060460 left lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the left lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060461 right lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the right lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060462 lung lobe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung. http://purl.obolibrary.org/obo/GO_0060463 lung lobe morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. http://purl.obolibrary.org/obo/GO_0060464 lung lobe formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung. http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. http://purl.obolibrary.org/obo/GO_0060495 cell-cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure. http://purl.obolibrary.org/obo/GO_0060496 mesenchymal-epithelial cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung. http://purl.obolibrary.org/obo/GO_0060497 mesenchymal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell. http://purl.obolibrary.org/obo/GO_0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. http://purl.obolibrary.org/obo/GO_0060502 epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. http://purl.obolibrary.org/obo/GO_0060532 bronchus cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0060533 bronchus cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060534 trachea cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0060535 trachea cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the anatomical structures of cartilage in the trachea are generated and organized. http://purl.obolibrary.org/obo/GO_0060539 diaphragm development http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. http://purl.obolibrary.org/obo/GO_0060540 diaphragm morphogenesis http://purl.obolibrary.org/obo/GO_0048644 muscle organ morphogenesis The process in which the anatomical structures of the diaphragm are generated and organized. http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. http://purl.obolibrary.org/obo/GO_0060574 intestinal epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus. http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine. http://purl.obolibrary.org/obo/GO_0060576 intestinal epithelial cell development http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060577 pulmonary vein morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. http://purl.obolibrary.org/obo/GO_0060578 superior vena cava morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. http://purl.obolibrary.org/obo/GO_0060591 chondroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes. http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted. http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted. http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/GO_0060842 arterial endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. http://purl.obolibrary.org/obo/GO_0060843 venous endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins. http://purl.obolibrary.org/obo/GO_0060915 mesenchymal cell differentiation involved in lung development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0060916 mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/GO_0060921 sinoatrial node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/GO_0060922 atrioventricular node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/GO_0060928 atrioventricular node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060931 sinoatrial node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/GO_0060933 His-Purkinje system cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0060935 cardiac fibroblast cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0060936 cardiac fibroblast cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0060945 cardiac neuron differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart. http://purl.obolibrary.org/obo/GO_0060946 cardiac blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/GO_0060950 cardiac glial cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart. http://purl.obolibrary.org/obo/GO_0060952 cardiac glial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell. http://purl.obolibrary.org/obo/GO_0060956 endocardial cell differentiation http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0060958 endocardial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. http://purl.obolibrary.org/obo/GO_0060959 cardiac neuron development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060978 angiogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001525 angiogenesis Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0060979 vasculogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0060980 cell migration involved in coronary vasculogenesis http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. http://purl.obolibrary.org/obo/GO_0060981 cell migration involved in coronary angiogenesis http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0061007 hepaticobiliary system process http://purl.obolibrary.org/obo/GO_0003008 system process A system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. http://purl.obolibrary.org/obo/GO_0061010 gallbladder development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The progression of the gallbladder over time, from its initial formation to the mature structure. The gallbladder is a cavitated organ that stores bile. http://purl.obolibrary.org/obo/GO_0061011 hepatic duct development http://purl.obolibrary.org/obo/GO_0061009 common bile duct development The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. http://purl.obolibrary.org/obo/GO_0061017 hepatoblast differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. http://purl.obolibrary.org/obo/GO_0061032 visceral serous pericardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. http://purl.obolibrary.org/obo/GO_0061040 female gonad morphogenesis http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis The process in which a female gonad is generated and organized. http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061047 positive regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061048 negative regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061051 positive regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061052 negative regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061054 dermatome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061055 myotome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. http://purl.obolibrary.org/obo/GO_0061056 sclerotome development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061072 iris morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. http://purl.obolibrary.org/obo/GO_0061073 ciliary body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. http://purl.obolibrary.org/obo/GO_0061074 regulation of neural retina development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061075 positive regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061076 negative regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061080 right horn of sinus venosus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the right horn of the sinus venosus from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061100 lung neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. http://purl.obolibrary.org/obo/GO_0061102 stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium. http://purl.obolibrary.org/obo/GO_0061105 regulation of stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. http://purl.obolibrary.org/obo/GO_0061106 negative regulation of stomach neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061105 regulation of stomach neuroendocrine cell differentiation Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach. http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. http://purl.obolibrary.org/obo/GO_0061111 epithelial-mesenchymal cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ. http://purl.obolibrary.org/obo/GO_0061113 pancreas morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. http://purl.obolibrary.org/obo/GO_0061114 branching involved in pancreas morphogenesis http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the branches of the pancreas are generated and organized. http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0061130 pancreatic bud formation http://purl.obolibrary.org/obo/GO_0061114 branching involved in pancreas morphogenesis The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. http://purl.obolibrary.org/obo/GO_0061147 endocardial endothelium development http://purl.obolibrary.org/obo/GO_0003158 endothelium development The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0061148 extracellular matrix organization involved in endocardium development http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0061152 trachea submucosa development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. http://purl.obolibrary.org/obo/GO_0061153 trachea gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0061155 pulmonary artery endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. http://purl.obolibrary.org/obo/GO_0061156 pulmonary artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. http://purl.obolibrary.org/obo/GO_0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus http://purl.obolibrary.org/obo/GO_0061178 regulation of insulin secretion involved in cellular response to glucose stimulus Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0061182 negative regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061184 positive regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061185 negative regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061189 positive regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061298 retina vasculature development in camera-type eye http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the vasculature of the retina is generated and organized. http://purl.obolibrary.org/obo/GO_0061304 retinal blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061307 cardiac neural crest cell differentiation involved in heart development http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. http://purl.obolibrary.org/obo/GO_0061325 cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/GO_0061337 cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. http://purl.obolibrary.org/obo/GO_0061383 trabecula morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. http://purl.obolibrary.org/obo/GO_0061385 fibroblast proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061453 interstitial cell of Cajal differentiation http://purl.obolibrary.org/obo/GO_0060575 intestinal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction. http://purl.obolibrary.org/obo/GO_0061484 hematopoietic stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a cilium. http://purl.obolibrary.org/obo/GO_0061523 cilium disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a cilium. http://purl.obolibrary.org/obo/GO_0061533 norepinephrine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061548 ganglion development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061549 sympathetic ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061551 trigeminal ganglion development http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of ganglion are generated and organized. http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061554 ganglion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061556 trigeminal ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis The process in which the anatomical structure of a trigeminal ganglion is generated and organized. http://purl.obolibrary.org/obo/GO_0061557 trigeminal ganglion maturation http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis The process in which the anatomical structure of a cranial ganglion is generated and organized. http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation http://purl.obolibrary.org/obo/GO_0061554 ganglion formation The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061561 trigeminal ganglion formation http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061626 pharyngeal arch artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling. http://purl.obolibrary.org/obo/GO_0070050 neuron cellular homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. http://purl.obolibrary.org/obo/GO_0070062 extracellular exosome http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. http://purl.obolibrary.org/obo/GO_0070091 glucagon secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/GO_0070093 negative regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/GO_0070094 positive regulation of glucagon secretion http://purl.obolibrary.org/obo/GO_0070092 regulation of glucagon secretion Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. http://purl.obolibrary.org/obo/GO_0070199 establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome The directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0070202 regulation of establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0070253 somatostatin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of somatostatin from secretory granules in the D cells of the pancreas. http://purl.obolibrary.org/obo/GO_0070254 mucus secretion http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0070256 negative regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0070257 positive regulation of mucus secretion http://purl.obolibrary.org/obo/GO_0070255 regulation of mucus secretion Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0070285 pigment cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070345 negative regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that stops or decreases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070346 positive regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that activates or increases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070365 hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/GO_0070367 negative regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation Any process that stops or decreases the rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/GO_0070368 positive regulation of hepatocyte differentiation http://purl.obolibrary.org/obo/GO_0070366 regulation of hepatocyte differentiation Any process that activates or increases the rate or extent of hepatocyte differentiation. http://purl.obolibrary.org/obo/GO_0070634 transepithelial ammonium transport http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport The directed movement of ammonium ions from one side of an epithelium to the other. http://purl.obolibrary.org/obo/GO_0070831 basement membrane assembly http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. http://purl.obolibrary.org/obo/GO_0070857 regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_1904251 regulation of bile acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/GO_0070858 negative regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_1904252 negative regulation of bile acid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/GO_0070859 positive regulation of bile acid biosynthetic process http://purl.obolibrary.org/obo/GO_1904253 positive regulation of bile acid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin The directed movement of a protein to a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/GO_0071311 cellular response to acetate http://purl.obolibrary.org/obo/GO_0010034 response to acetate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus. http://purl.obolibrary.org/obo/GO_0071312 cellular response to alkaloid http://purl.obolibrary.org/obo/GO_0043279 response to alkaloid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active. http://purl.obolibrary.org/obo/GO_0071326 cellular response to monosaccharide stimulus http://purl.obolibrary.org/obo/GO_0071322 cellular response to carbohydrate stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. http://purl.obolibrary.org/obo/GO_0071425 hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072089 stem cell proliferation The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop. http://purl.obolibrary.org/obo/GO_0071626 mastication http://purl.obolibrary.org/obo/GO_0022600 digestive system process The process of biting and mashing food with the teeth prior to swallowing. http://purl.obolibrary.org/obo/GO_0071696 ectodermal placode development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0071697 ectodermal placode morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0071764 nuclear outer membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. http://purl.obolibrary.org/obo/GO_0071868 cellular response to monoamine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine http://purl.obolibrary.org/obo/GO_0071867 response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/GO_0071870 cellular response to catecholamine stimulus http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0071874 cellular response to norepinephrine stimulus http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0071953 elastic fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. http://purl.obolibrary.org/obo/GO_0071971 extracellular exosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0072360 vascular cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. http://purl.obolibrary.org/obo/GO_0072560 type B pancreatic cell maturation http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin. http://purl.obolibrary.org/obo/GO_0072575 epithelial cell proliferation involved in liver morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver. http://purl.obolibrary.org/obo/GO_0072576 liver morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the liver are generated and organized. http://purl.obolibrary.org/obo/GO_0072577 endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. http://purl.obolibrary.org/obo/GO_0072592 oxygen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving diatomic oxygen (O2). http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained at, a location in a vacuole. http://purl.obolibrary.org/obo/GO_0080144 intracellular amino acid homeostasis http://purl.obolibrary.org/obo/GO_0055082 intracellular chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of amino acids within a cell. http://purl.obolibrary.org/obo/GO_0090425 acinar cell differentiation http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. http://purl.obolibrary.org/obo/GO_0097084 vascular associated smooth muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. http://purl.obolibrary.org/obo/GO_0097712 vesicle targeting, trans-Golgi to periciliary membrane compartment http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_0098771 inorganic ion homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901464 negative regulation of tetrapyrrole biosynthetic process http://purl.obolibrary.org/obo/GO_1901463 regulation of tetrapyrrole biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process. http://purl.obolibrary.org/obo/GO_1901465 positive regulation of tetrapyrrole biosynthetic process http://purl.obolibrary.org/obo/GO_1901463 regulation of tetrapyrrole biosynthetic process Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process. http://purl.obolibrary.org/obo/GO_1901653 cellular response to peptide http://purl.obolibrary.org/obo/GO_1901652 response to peptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/GO_1901963 regulation of cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902339 positive regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction http://purl.obolibrary.org/obo/GO_0008104 protein localization A process in which a protein is transported to, or maintained in, a location within a cell junction. http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the extracellular region. http://purl.obolibrary.org/obo/GO_1903867 extraembryonic membrane development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an epithelial cell. http://purl.obolibrary.org/obo/GO_1904251 regulation of bile acid metabolic process http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process Any process that modulates the frequency, rate or extent of bile acid metabolic process. http://purl.obolibrary.org/obo/GO_1904252 negative regulation of bile acid metabolic process http://purl.obolibrary.org/obo/GO_1904251 regulation of bile acid metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process. http://purl.obolibrary.org/obo/GO_1904253 positive regulation of bile acid metabolic process http://purl.obolibrary.org/obo/GO_1904251 regulation of bile acid metabolic process Any process that activates or increases the frequency, rate or extent of bile acid metabolic process. http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905278 positive regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that activates or increases the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905293 negative regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905294 positive regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905349 ciliary transition zone assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1905516 positive regulation of fertilization http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of fertilization. http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization. http://purl.obolibrary.org/obo/GO_1990748 cellular detoxification http://purl.obolibrary.org/obo/GO_0098754 detoxification Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance. http://purl.obolibrary.org/obo/GO_2000543 positive regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that activates or increases the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/GO_2001012 mesenchymal cell differentiation involved in renal system development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/GO_2001055 positive regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/PR_000009054 insulin gene translation product http://purl.obolibrary.org/obo/PR_000045358 insulin family protein An insulin family protein that is a translation product of the human INS gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000045358 insulin family protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of a gene that encodes a standalone Insulin (Pfam:PF00049) domain preceded by a signal peptide. http://purl.obolibrary.org/obo/PR_Q62226 sonic hedgehog protein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sonic hedgehog protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P10810 monocyte differentiation antigen CD14 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD14 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P11836 B-lymphocyte antigen CD20 (human) http://purl.obolibrary.org/obo/PR_000029067 Homo sapiens protein A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of human. http://purl.obolibrary.org/obo/PR_P13379 T-cell surface glycoprotein CD5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P13595 neural cell adhesion molecule 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neural cell adhesion molecule 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0036214 rectosigmoid junction http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction An anatomical junction that is between the sigmoid colon and rectum. http://purl.obolibrary.org/obo/GO_0062237 protein localization to postsynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue A muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/CL_4033018 lung megakaryocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A megakaryocyte that is resident in the lung connective tissue. http://purl.obolibrary.org/obo/CL_4033054 perivascular cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics. http://purl.obolibrary.org/obo/CL_4040004 mesenchymal stem cell of orbital adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an orbital region. http://purl.obolibrary.org/obo/CHEBI_228364 NMR chemical shift reference compound http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any compound that produces a peak used as reference frequency in the delta chemical shift scale. http://purl.obolibrary.org/obo/ECAO_0000610 open mouth stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent This stage is characterized by the opening of the mouth. The right and left coelomic pouches are prominent and well-separated from the foregut by narrow coelomic constrictions. Pronounced cardiac and developing pyloric constrictions (separating respectively the foregut and midgut, and the midgut and hindgut) are visible; the gut is thus visibly tripartite. The developing stomach (former midgut) is enlarged relative to the other segments of the gut and muscle bands surrounding the esophagus are apparent. The ciliary band(s) is (are) also discernable. http://purl.obolibrary.org/obo/ECAO_0000620 early prism stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has a distinctive, angular shape due to the elongation of the skeletal rods. The body rods have elongated toward the apex (posterior end) of the embryo. The dorsoventral connecting rods are elongated, and the postoral rods are still very short although they already support thickened regions of ectoderm that will later form the distal tip of the postoral arms. The archenteron tip is slightly expanded, and its oral surface is directed toward the oral ectoderm. Ingression of secondary mesenchyme cells (SMCs) is complete. The embryo is reddish in color due to the presence of pigment cells within the aboral ectoderm. The animal pole domain (or apical plate) is prominent and the lateral walls of the embryo have thinned. The coelomic pouches and gut constrictions have not yet appeared. http://purl.obolibrary.org/obo/ECAO_0000630 late prism stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has a distinctive, angular shape due to the elongation of the skeletal rods. The body rods have expended even further compared to earlier stages and the postoral rods support short postoral arm buds. The anterior ends of the dorsoventral connecting rods are also now branched or bent. The archenteron tip is still bent toward the oral ectoderm. At the tip of the archenteron coelomic evaginations start to be apparent, although no gut constrictions are visible yet. The embryo is reddish in color due to the presence of pigment cells within the aboral ectoderm. The animal pole domain is prominent, and it still bears long, immotile cilia. http://purl.obolibrary.org/obo/ECAO_0000640 early pluteus stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent early pluteus stage http://purl.obolibrary.org/obo/ECAO_0000650 early organogenesis stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is elongated along the animal-vegetal axis and has thus a characteristic oblong shape. The archenteron is fully extended, even though it still does not reach the blastocoel roof. The tip of the archenteron is enlarged, rounded, and smooth, and the archenteron has begun to deflect orally. Mesenchyme cell ingression is complete. However, paired coelomic pouches and gut constrictions have not yet formed. http://purl.obolibrary.org/obo/ECAO_0000660 mid-organogenesis stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is elongated along the animal-vegetal axis and has thus a characteristic oblong shape. The archenteron is overall deflected orally and its tip is enlarged, rounded, and smooth. The tip of the archenteron is further starting to display filopodia that interact with the ectoderm site where the mouth will form. At the tip of the archenteron, unpaired evaginations of the coelom are also now apparent, even though the stomodeal invagination, gut constrictions, and ciliary band(s) are still not discernable. Mesenchyme cells have dispersed through the blastocoel. http://purl.obolibrary.org/obo/ECAO_0000670 late organogenesis stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is characterized by the presence, at the tip of the archenteron, of two well-formed coelomic pouches, separated from the foregut by pronounced constrictions. The cardiac constriction, which separates the foregut and the midgut, has started to form. On the oral side of the embryo, the stomodeal invagination is visible, although the mouth has not yet opened. The ciliary band(s) is (are) not yet visible. http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A population of embryonic cells that share a common developmental fate or program of gene expression and comprising a region that lacks clear morphological boundaries http://purl.obolibrary.org/obo/ECAO_0107570 adult organism http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism A multicellular organism that existence_ends_with a post-juvenile adult stage and existence_starts_with a post-juvenile adult stage. http://purl.obolibrary.org/obo/ECAO_0107580 embryonic muscular system http://purl.obolibrary.org/obo/ECAO_0103770 muscular system The muscle system of the embryo. http://purl.obolibrary.org/obo/ECAO_0107590 extracellular matrix http://purl.obolibrary.org/obo/ECAO_0104270 acellular membrane A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. http://purl.obolibrary.org/obo/ECAO_0107600 blastomere of 8-cell embryo http://purl.obolibrary.org/obo/ECAO_0104630 blastomere A blastomere of an 8-cell embryo. http://purl.obolibrary.org/obo/ECAO_0107610 blastomere of 16-cell embryo http://purl.obolibrary.org/obo/ECAO_0104630 blastomere A blastomere of a 16-cell embryo. http://purl.obolibrary.org/obo/ECAO_0107620 presumptive animal pole domain neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron A cell that will develop into a neuron of the animal pole domain. http://purl.obolibrary.org/obo/ECAO_0107630 presumptive ectoderm neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron An ectodermal cell that will develop into a neuron. http://purl.obolibrary.org/obo/ECAO_0107640 presumptive ciliary band neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron A cell that will develop into a neuron of the ciliary band. http://purl.obolibrary.org/obo/ECAO_0107650 presumptive endoderm-associated neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron An endodermal cell that will develop into a neuron. http://purl.obolibrary.org/obo/ECAO_0107660 postoral neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron A neuron located near the base of an oral arm and outside the ciliary band. http://purl.obolibrary.org/obo/ECAO_0107670 presumptive postoral neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron A cell that will give rise to a postoral neuron. http://purl.obolibrary.org/obo/ECAO_0107680 synaptotagmin-B-expressing neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron A neuron that produces the synaptotagmin-B protein. http://purl.obolibrary.org/obo/ECAO_0107690 nitric oxide synthase-expressing neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron A neuron that produces the nitric oxide synthase protein. http://purl.obolibrary.org/obo/ECAO_0107700 cholinergic neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron A neuron that uses acetylcholine as a vesicular neurotransmitter. http://purl.obolibrary.org/obo/ECAO_0107710 catecholaminergic/cholinergic neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron A neuron that uses both acetylcholine and catecholamines as vesicular neurotransmitters. http://purl.obolibrary.org/obo/ECAO_0107720 endoderm-associated neuron http://purl.obolibrary.org/obo/ECAO_0104800 larval neuron A neuron derived from endoderm. http://purl.obolibrary.org/obo/ECAO_0107730 lateral ganglion http://purl.obolibrary.org/obo/ECAO_0104930 ganglion One of two bilateral ganglia that arise in the oral ectoderm near the ciliary band. http://purl.obolibrary.org/obo/ECAO_0107740 right lateral ganglion http://purl.obolibrary.org/obo/ECAO_0107730 lateral ganglion The lateral ganglion that forms on the right side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107750 left lateral ganglion http://purl.obolibrary.org/obo/ECAO_0107730 lateral ganglion The lateral ganglion that forms on the left side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107760 presumptive ventral ectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory The part of the blastula that will give rise to ventral ectoderm. http://purl.obolibrary.org/obo/ECAO_0107770 presumptive dorsal ectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory The part of the blastula that will give rise to dorsal ectoderm. http://purl.obolibrary.org/obo/ECAO_0107780 anterior neuroectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory A dynamic terriritory within the prospective ectoderm of the early embryo, located at the anterior (animal) end of the embryo and shaped by Wnt signaling, that contains cells with neurogenic potential. http://purl.obolibrary.org/obo/ECAO_0107790 equatorial ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A dynamic territory within the prospective ectoderm of the early embryo, located between the anterior neuroectoderm and the endomesoderm. http://purl.obolibrary.org/obo/ECAO_0107800 inner anterior neuroectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The innermost part of the anterior neuroectoderm, immediately surrounding the animal pole. http://purl.obolibrary.org/obo/ECAO_0107810 outer anterior neuroectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A torus shaped region comprising the outer part of the anterior neuroectoderm. http://purl.obolibrary.org/obo/ECAO_0107820 central ventral ectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory A region of the ectoderm derived from the animal hemisphere (i.e., mesomere descendants) and located just above the equator on the ventral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107830 near apical ectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory A region of the ectoderm derived from the animal hemisphere (i.e., mesomere descendants) and located between the central ventral ectoderm and the animal pole domain on the ventral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107840 lateral border ectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory A region of border ectoderm located on a lateral surface of the embryo. http://purl.obolibrary.org/obo/ECAO_0107850 ventral border ectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory A region of border ectoderm located on the ventral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107860 dorsal border ectoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory A region of border ectoderm located on the dorsal side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107870 animal lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A region of ectoderm derived from the animal hemisphere and located laterally at the boundary between hte ventral and dorsal ectoderm; this region overlaps with part of the prospective ciliary band. http://purl.obolibrary.org/obo/ECAO_0107880 right animal lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0105320 lateral ectoderm The animal lateral ectoderm on the right side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107890 left animal lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0105320 lateral ectoderm The animal lateral ectoderm on the left side of the embryo. http://purl.obolibrary.org/obo/ECAO_0107900 postoral arm tip ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A portion of the ectoderm located at the tip of a postoral arm. http://purl.obolibrary.org/obo/ECAO_0107910 right postoral arm tip ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A portion of the ectoderm located at the tip of the right postoral arm. http://purl.obolibrary.org/obo/ECAO_0107920 left postoral arm tip ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A portion of the ectoderm located at the tip of the left postoral arm. http://purl.obolibrary.org/obo/ECAO_0107930 presumptive ciliary band http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory The cells that will give rise to the ciliary band. http://purl.obolibrary.org/obo/ECAO_0107940 arm http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure An elongated extension of the embryo on the ventral side, supported by a simple or fenestrated skeletal rod and often covered in part by a ciliary band. Arms develop in bilaterally symmetrical pairs. http://purl.obolibrary.org/obo/ECAO_0107950 anterolateral arm http://purl.obolibrary.org/obo/ECAO_0107940 arm A type of arm that projects from the oral hood; forms after the postoral arms appear and prior to the appearance of the preoral and posterodorsal arms. http://purl.obolibrary.org/obo/ECAO_0107960 postoral arm http://purl.obolibrary.org/obo/ECAO_0107940 arm A type of arm that forms between the equator and the posterior pole, near the position of the skeletal rudiment; the first type of arm to appear. http://purl.obolibrary.org/obo/ECAO_0107970 anterolateral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod A rod that forms by the branching or pronounced curving of the anterior tip of a dorsoventral connecting rod and that projects ventrally from the oral hood, supporting an anterolateral arm. http://purl.obolibrary.org/obo/ECAO_0107980 postoral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod A rod that forms by the branching of the anonymous rod and projects ventrally, supporting a postoral arm. http://purl.obolibrary.org/obo/ECAO_0107990 dorsoventral connecting rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod A rod that initially forms as one of the three arms of the embryonic triradiate spicule rudiment; this rod extends toward the animal pole before branching or curving to form the anterolateral rod and, in some species, the recurrent rod. http://purl.obolibrary.org/obo/ECAO_0108000 ventral transverse rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod A rod that initially forms as one of the three arms of the embryonic triradiate spicule rudiment; this rod projects toward the ventral midline and ceases growth early in development without branching. http://purl.obolibrary.org/obo/ECAO_0108010 distal tip of body rod http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element The growing tip of the body rod as it extends dorsally. http://purl.obolibrary.org/obo/ECAO_0108020 distal tip of right body rod http://purl.obolibrary.org/obo/ECAO_0105868 posterior tip of body rod The distal tip of the body rod that forms on the right side of the embryo. http://purl.obolibrary.org/obo/ECAO_0108030 distal tip of left body rod http://purl.obolibrary.org/obo/ECAO_0105868 posterior tip of body rod The distal tip of the body rod that forms on the left side of the embryo.. http://purl.obolibrary.org/obo/ECAO_0108040 recurrent rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod A rod that forms from the branching of a dorsoventral transverse rod and extends dorsally. http://purl.obolibrary.org/obo/ECAO_0108050 presumptive embryonic skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory The part of the embryonic presumptive mesoderm that will later give rise to the skeletogenic mesenchyme and embryonic skeleton. http://purl.obolibrary.org/obo/ECAO_0108060 ventrolateral skeletogenic mesenchyme cluster http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure A cluster of skeletogenic cell bodies that forms in the ventrolateral region of the subequatorial skeletogenic mesenchyme ring; one triradiate spicule rudiment will form in each of two ventrolateral clusters. http://purl.obolibrary.org/obo/ECAO_0108070 presumptive embryonic non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory Embryonic cells tin the epithelial wall of the vegetal plate or the archenteron that will give rise to mesodermal derivatives other than skeleton. http://purl.obolibrary.org/obo/ECAO_0108080 ventral presumptive embryonic non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory The presumptive embryonic non-skeletogenic mesoderm on the ventral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0108090 dorsal presumptive embryonic non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0107560 embryonic territory The presumptive embryonic non-skeletogenic mesoderm on the dorsal side of the embryo. http://purl.obolibrary.org/obo/ECAO_0108100 presumptive muscle cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that will give rise to a muscle cell. http://purl.obolibrary.org/obo/ECAO_0108110 muscle cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that is part of a muscle. http://purl.obolibrary.org/obo/ECAO_0108120 presumptive blastocoel http://purl.obolibrary.org/obo/ECAO_0103540 anatomical space The inner, extracellular space between blastomeres of the cleavage stage embryo that will gradually expand and form the blastocoel. http://purl.obolibrary.org/obo/ECAO_0108130 pyloric sphincter muscle cell http://purl.obolibrary.org/obo/ECAO_0106660 sphincter muscle cell A cell that is part of the pyloric sphincter. http://purl.obolibrary.org/obo/ECAO_0108140 cardiac sphincter muscle cell http://purl.obolibrary.org/obo/ECAO_0106660 sphincter muscle cell A cell that is part of the cardiac sphincter. http://purl.obolibrary.org/obo/ECAO_0108150 anal sphincter muscle cell http://purl.obolibrary.org/obo/ECAO_0106660 sphincter muscle cell A cell that is part of the anal sphincter. http://purl.obolibrary.org/obo/ECAO_0108160 primary pore canal rudiment http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure A strand of mesenchyme cells that extends from the left coelom to the ectoderm and that will give rise to the primary pore canal. http://purl.obolibrary.org/obo/ECAO_0108170 posterior enterocoel http://purl.obolibrary.org/obo/ECAO_0106770 coelom An evagination of the midgut that will contribute to the coelom. http://purl.obolibrary.org/obo/ECAO_0108180 left anterior coelomic pouch http://purl.obolibrary.org/obo/ECAO_0106770 coelom In species with a posterior enterocoel, the left coelomic pouch that evaginates from the unpaired coelomic pouch at the anterior end of the archenteron. http://purl.obolibrary.org/obo/ECAO_0108190 right anterior coelomic pouch http://purl.obolibrary.org/obo/ECAO_0106770 coelom In species with a posterior enterocoel, the right coelomic pouch that evaginates from the unpaired coelomic pouch at the anterior end of the archenteron. http://purl.obolibrary.org/obo/ECAO_0108200 preoral ciliary band http://purl.obolibrary.org/obo/ECAO_0105460 ciliary band In species with two separate ciliary bands, a ciliary band that surrounds the anterior-ventral end of the embryo, anterior to the mouth. http://purl.obolibrary.org/obo/ECAO_0108210 postoral ciliary band http://purl.obolibrary.org/obo/ECAO_0105460 ciliary band In species with two separate ciliary bands, a ciliary band that surrounds the posterior-dorsal end of the embryo, posterior to the mouth. http://purl.obolibrary.org/obo/ECAO_0000235 64-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 64 cells and is surrounded by a fertilization envelope. http://purl.obolibrary.org/obo/ECAO_0000700 motile blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 400-500 cells and is no longer surrounded by a fertilization envelope. Most cells have completed at least one additional mitotic division after the early blastula stage and the cell divisions are now less synchronous than at earlier stages. The embryo remains spherical in shape and one cell layer thick. It does not display any morphological indications of the embryonic axes or of the vegetal plate. The cells have started to flatten on their inner (basal) surface, further contributing to the enlargement of the blastocoel, which has expanded since the early blastula stage. http://purl.obolibrary.org/obo/ECAO_0000710 invagination episode http://purl.obolibrary.org/obo/BFO_0000003 occurrent The second episode of the gastrulation period, characterized by the invagination of the vegetal plate into the blastocoel to form the primitive digestive tract (archenteron). http://purl.obolibrary.org/obo/ECAO_0109000 anatomical element http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure An anatomical structure that is a subdivision of a tissue, a germ layer, or an organ of the whole organism but with well-defined morphological boundaries. http://purl.obolibrary.org/obo/ECAO_0109010 zygote http://purl.obolibrary.org/obo/ECAO_0104030 cell A diploid cell produced by the fusion of a male and a female gamete at fertilization. It constitutes the first stage of the embryogenesis life cycle phase. http://purl.obolibrary.org/obo/ECAO_0109020 cleavage embryo http://purl.obolibrary.org/obo/ECAO_0103570 embryo A multicellular organism at an early stage of development characterized by cleavage. It includes all forms of the cleavage period during the embryogenesis life cycle phase (i.e., from first cleavage to before the formation of the blastula). http://purl.obolibrary.org/obo/ECAO_0109030 blastula http://purl.obolibrary.org/obo/ECAO_0103570 embryo A multicellular organism at an early stage of development corresponding to a hollow, spherical, multicellular, monolayered embryo with a hollow cavity (the blastocoel) in the center. It includes all forms of the blastula period during the embryogenesis life cycle phase. http://purl.obolibrary.org/obo/ECAO_0109040 gastrula http://purl.obolibrary.org/obo/ECAO_0103570 embryo A multicellular organism at an early stage of development characterized by morphogenetic movements. It includes all forms of the gastrula period during the embryogenesis life cycle phase. http://purl.obolibrary.org/obo/ECAO_0109050 pre-metamorphic organism http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism A multicellular organism the existence of which starts at fertilization and ends with metamorphosis. It includes all forms during the embryogenesis and larval development life cycle phases. http://purl.obolibrary.org/obo/ECAO_0109060 post-embryonic organism http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism A multicellular organism the existence of which starts upon the opening of the mouth and ends with death. It includes all forms during the larval development and adulthood phase life cycle phases. http://purl.obolibrary.org/obo/ECAO_0109070 mature adult http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism A multicellular organism the existence of which starts with gamete production and ends with death. http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A portion of an embryo (or a population of embryonic cells) that is characterized by a common developmental fate or a common gene expression program but lacks any clear morphological boundaries. http://purl.obolibrary.org/obo/ECAO_0109090 larval region http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A portion of a larva (or a population of larval cells) that is characterized by a common developmental fate or a common gene expression program but lacks any clear morphological boundaries. http://purl.obolibrary.org/obo/ECAO_0109100 pre-metamorphic organism region http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region A population of cells that, throughout the embryogenesis and larval development life cycle phases, is characterized by a common developmental fate or a common gene expression program but lacks any clear morphological boundaries. http://purl.obolibrary.org/obo/ECAO_0109110 organ http://purl.obolibrary.org/obo/ECAO_0109000 anatomical element A multicellular anatomical structure made of several tissues, performing a specific function or group of functions. http://purl.obolibrary.org/obo/ECAO_0109120 pre-metamorphic organism tissue http://purl.obolibrary.org/obo/ECAO_0104110 tissue A tissue that is present in a pre-metamorphic organism. http://purl.obolibrary.org/obo/ECAO_0109130 pre-metamorphic organism structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure An anatomical structure that is part of a pre-metamorphic organism. http://purl.obolibrary.org/obo/ECAO_0109140 pre-metamorphic organism immune system http://purl.obolibrary.org/obo/ECAO_0103660 immune system The immune system of a pre-metamorphic organism. http://purl.obolibrary.org/obo/ECAO_0109150 female reproductive system http://purl.obolibrary.org/obo/ECAO_0103710 reproductive system An anatomical reproductive system that is present in a female multicellular organism. http://purl.obolibrary.org/obo/ECAO_0109160 male reproductive system http://purl.obolibrary.org/obo/ECAO_0103710 reproductive system An anatomical reproductive system that is present in a male multicellular organism. http://purl.obolibrary.org/obo/ECAO_0109170 pre-metamorphic organism nervous system http://purl.obolibrary.org/obo/ECAO_0103720 nervous system The neurons and glial cells constituting the nervous system of a pre-metamorphic organism. http://purl.obolibrary.org/obo/ECAO_0109180 pre-metamorphic organism endoskeleton http://purl.obolibrary.org/obo/ECAO_0103810 endoskeleton The endoskeleton of a pre-metamorphic organism. http://purl.obolibrary.org/obo/ECAO_0109190 skeletal tissue http://purl.obolibrary.org/obo/ECAO_0104110 tissue A specialized form of connective tissue in which the extracellular matrix is mineralized and that functions in mechanical and structural support. http://purl.obolibrary.org/obo/ECAO_0109200 embryonic hemisphere http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure One of two hemispheres of an embryo. http://purl.obolibrary.org/obo/ECAO_0109210 animal cell tier http://purl.obolibrary.org/obo/ECAO_0104678 cell tier A cell tier present in the animal hemisphere of an embryo. http://purl.obolibrary.org/obo/ECAO_0109220 vegetal cell tier http://purl.obolibrary.org/obo/ECAO_0104678 cell tier A cell tier present in the vegetal hemisphere of an embryo. http://purl.obolibrary.org/obo/ECAO_0109230 cell body http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure The portion of a cell bearing surface projections such as axons, filopodia, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. http://purl.obolibrary.org/obo/ECAO_0109240 germ line cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. http://purl.obolibrary.org/obo/ECAO_0109250 female germ cell http://purl.obolibrary.org/obo/ECAO_0104570 germ cell A germ cell that supports female gamete production. http://purl.obolibrary.org/obo/ECAO_0109260 male germ cell http://purl.obolibrary.org/obo/ECAO_0104570 germ cell A germ cell that supports male gamete production. http://purl.obolibrary.org/obo/ECAO_0109270 mature germ cell http://purl.obolibrary.org/obo/ECAO_0104570 germ cell The reproductive haploid, mature sexual reproductive cell of a multicellular organism. http://purl.obolibrary.org/obo/ECAO_0109280 primary oocyte http://purl.obolibrary.org/obo/ECAO_0104560 primordial germ cell An immature oocyte that is diploid and has not completed female meiosis I. http://purl.obolibrary.org/obo/ECAO_0109290 secondary oocyte http://purl.obolibrary.org/obo/ECAO_0104560 primordial germ cell An immature oocyte that is haploid but has not completed female meiosis II. http://purl.obolibrary.org/obo/ECAO_0109300 spermatogonium http://purl.obolibrary.org/obo/ECAO_0104560 primordial germ cell An euploid male germ cell of an early stage of spermatogenesis. It is morphologically unlike spermatocytes and spermatids. http://purl.obolibrary.org/obo/ECAO_0109310 spermatocyte http://purl.obolibrary.org/obo/ECAO_0104560 primordial germ cell A male germ cell that develops from spermatogonia. http://purl.obolibrary.org/obo/ECAO_0109320 spermatid http://purl.obolibrary.org/obo/ECAO_0104560 primordial germ cell A male germ cell that develops from spermatocytes. http://purl.obolibrary.org/obo/ECAO_0109330 spermatozoid nucleus http://purl.obolibrary.org/obo/ECAO_0104160 nucleus An intracellular anatomical structure in which the male chromosomes are housed. http://purl.obolibrary.org/obo/ECAO_0109340 oocyte nucleus http://purl.obolibrary.org/obo/ECAO_0104160 nucleus An intracellular anatomical structure in which the female chromosomes are housed. http://purl.obolibrary.org/obo/ECAO_0109350 cellular anatomical entity http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Any constituent part of a cell that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical structure. http://purl.obolibrary.org/obo/ECAO_0109360 intracellular anatomical structure http://purl.obolibrary.org/obo/ECAO_0109350 cellular anatomical entity A component of a cell contained within (but not including) the plasma membrane. It includes as examples the nucleus, mitochondria, vesicles, and the cytoskeleton. http://purl.obolibrary.org/obo/ECAO_0109370 cell-cell junction http://purl.obolibrary.org/obo/ECAO_0109350 cellular anatomical entity A cell junction that forms a connection between two or more cells of a multicellular organism. http://purl.obolibrary.org/obo/ECAO_0109380 desmosome http://purl.obolibrary.org/obo/ECAO_0109370 cell-cell junction A strong cell-cell junction usually found in tissue that experience intense mechanical stress. http://purl.obolibrary.org/obo/ECAO_0109390 septate junction http://purl.obolibrary.org/obo/ECAO_0109370 cell-cell junction A cell-cell junction that forms a continuous band around each cell in an epithelium. http://purl.obolibrary.org/obo/ECAO_0109400 adherens junction http://purl.obolibrary.org/obo/ECAO_0109370 cell-cell junction A cell-cell junction composed of the epithelial cadherin-catenin complex. http://purl.obolibrary.org/obo/ECAO_0109410 microtubule cytoskeleton http://purl.obolibrary.org/obo/ECAO_0104148 cytoskeleton The part of the cytoskeleton composed of microtubules and associated proteins. http://purl.obolibrary.org/obo/ECAO_0109420 filament http://purl.obolibrary.org/obo/ECAO_0109360 intracellular anatomical structure A component of a cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. http://purl.obolibrary.org/obo/ECAO_0109430 spindle pole http://purl.obolibrary.org/obo/ECAO_0109360 intracellular anatomical structure The either end of a spindle, from where the spindle microtubules emanate. http://purl.obolibrary.org/obo/ECAO_0109440 equator region http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The middle region of an oocyte or a zygote, which comprises the most basal portion of the animal and vegetal hemispheres. http://purl.obolibrary.org/obo/ECAO_0109450 kinetochore http://purl.obolibrary.org/obo/ECAO_0109350 cellular anatomical entity A multisubunit complex that is located on chromosomes and provides an attachment point for the spindle microtubules. http://purl.obolibrary.org/obo/ECAO_0109460 apical cilium http://purl.obolibrary.org/obo/ECAO_0104340 cilium A cilium that develops on the apical surface of a cell. http://purl.obolibrary.org/obo/ECAO_0109470 short motile cilium http://purl.obolibrary.org/obo/ECAO_0104340 cilium A cilium of short size exhibiting motility thanks to the molecular motors it contains. In echinoderms, short motile cilia are encountered on the outer surface of the developing embryo as well as in the developing and developed digestive tract of embryos and larvae. http://purl.obolibrary.org/obo/ECAO_0109480 long immotile cilium http://purl.obolibrary.org/obo/ECAO_0104340 cilium A cilium of long size that does not contain molecular motors and as such does not exhibit any beating movement. In some echinoderms, long immotile cilia are found, when present, at the animal pole of embryos and constitute the apical tuft. http://purl.obolibrary.org/obo/ECAO_0109490 filopodial cable http://purl.obolibrary.org/obo/ECAO_0109350 cellular anatomical entity A sheet-like cellular projection that is supported by an ordered network of actin filaments and that is involved in cellular motility and syncytium formation. http://purl.obolibrary.org/obo/ECAO_0109500 nucleolus http://purl.obolibrary.org/obo/ECAO_0109360 intracellular anatomical structure A small, dense body present in the nucleus of cells and that is rich in RNA and protein, not bounded by a limiting membrane, and not seen during mitosis. http://purl.obolibrary.org/obo/ECAO_0109510 chromosome http://purl.obolibrary.org/obo/ECAO_0109360 intracellular anatomical structure A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. http://purl.obolibrary.org/obo/ECAO_0109520 animal blastomere http://purl.obolibrary.org/obo/ECAO_0104630 blastomere An undifferentiated cell part of the animal hemisphere of an embryo. http://purl.obolibrary.org/obo/ECAO_0109530 vegetal blastomere http://purl.obolibrary.org/obo/ECAO_0104630 blastomere An undifferentiated cell part of the vegetal hemisphere of an embryo. http://purl.obolibrary.org/obo/ECAO_0109540 macromere descendant cell http://purl.obolibrary.org/obo/ECAO_0104010 embryonic cell A cell derived from a macromere through cell division. http://purl.obolibrary.org/obo/ECAO_0109550 presumptive blastocoel http://purl.obolibrary.org/obo/ECAO_0103540 anatomical space The inner, extracellular space between blastomeres of the cleavage stage embryos that will gradually expand and form the blastocoel. http://purl.obolibrary.org/obo/ECAO_0109560 blastocoel roof http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The most apical region of the blastocoel. http://purl.obolibrary.org/obo/ECAO_0109570 blastocoel wall http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The region of the blastocoel comprised in the middle region of the embryo, below the blastocoel roof. http://purl.obolibrary.org/obo/ECAO_0109580 ectoderm cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell part of the ectoderm germ layer. http://purl.obolibrary.org/obo/ECAO_0109590 epidermis http://purl.obolibrary.org/obo/ECAO_0104110 tissue An epithelium derived from ectoderm and constituting the outermost protective layer of an embryo, a larva, or an adult. http://purl.obolibrary.org/obo/ECAO_0109600 epithelium http://purl.obolibrary.org/obo/ECAO_0104110 tissue A tissue that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. http://purl.obolibrary.org/obo/ECAO_0109610 embryonic ectoderm http://purl.obolibrary.org/obo/ECAO_0104908 ectoderm The ectoderm that is specifically present in an embryo http://purl.obolibrary.org/obo/ECAO_0109620 larval ectoderm http://purl.obolibrary.org/obo/ECAO_0104908 ectoderm The ectoderm that is specifically present in a larva. http://purl.obolibrary.org/obo/ECAO_0109630 pre-metamorphic organism ectoderm http://purl.obolibrary.org/obo/ECAO_0104908 ectoderm The ectoderm that is specifically present in an embryo and a larva but not in an adult. http://purl.obolibrary.org/obo/ECAO_0109640 vegetal tier 1 ectoderm http://purl.obolibrary.org/obo/ECAO_0105160 presumptive ectoderm The ectoderm that specifically derives from cells of the veg1 tier. http://purl.obolibrary.org/obo/ECAO_0109650 non-apical ectoderm http://purl.obolibrary.org/obo/ECAO_0105160 presumptive ectoderm The ectoderm that is part of the animal ectoderm but located below the apical pole domain ectoderm. http://purl.obolibrary.org/obo/ECAO_0109660 apical pole domain http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region A thickened region at the animal hemisphere, located at the animal pole, and that contains developing neurons and cells with elongated cilia. http://purl.obolibrary.org/obo/ECAO_0109670 apical pole domain ectoderm http://purl.obolibrary.org/obo/ECAO_0105180 animal ectoderm The ectoderm that is part of the animal ectoderm and is specifically restricted to the apical pole domain. http://purl.obolibrary.org/obo/ECAO_0109680 presumptive oral ectoderm http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The portion of the presumptive ectoderm that is located on the oral side of the embryo (which will later generate the ventral side of the larva). http://purl.obolibrary.org/obo/ECAO_0109690 oral ectoderm http://purl.obolibrary.org/obo/ECAO_0105160 presumptive ectoderm The portion of the embryonic ectoderm that is located on the oral side of the embryo and will give rise to ventral ectoderm of the larva. http://purl.obolibrary.org/obo/ECAO_0109700 presumptive aboral ectoderm http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The portion of the presumptive ectoderm that is located on the aboral side of the embryo (which will later generate the dorsal side of the larva). http://purl.obolibrary.org/obo/ECAO_0109710 aboral ectoderm http://purl.obolibrary.org/obo/ECAO_0105160 presumptive ectoderm The portion of the embryonic ectoderm that is located on the aboral side of the embryo and will give rise to dorsal ectoderm of the larva. http://purl.obolibrary.org/obo/ECAO_0109720 oral border ectoderm http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The portion of the border ectoderm that is located on the oral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0109730 aboral border ectoderm http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The portion of the border ectoderm that is located on the aboral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0109740 stomodeal presumptive ectoderm http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The portion of the presumptive oral ectoderm where the stomodeum will form. http://purl.obolibrary.org/obo/ECAO_0109750 stomodeal ectoderm http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The portion of the oral ectoderm where the stomodeum forms. http://purl.obolibrary.org/obo/ECAO_0109760 neuroectoderm http://purl.obolibrary.org/obo/ECAO_0104110 tissue The portion of the ectoderm where neurons form. http://purl.obolibrary.org/obo/ECAO_0109770 presumptive apical pole domain neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron An ectodermal progenitor cell from the animal pole domain that will develop into a neuron. http://purl.obolibrary.org/obo/ECAO_0109780 presumptive endoderm neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron An endodermal cell that will develop into a neuron. http://purl.obolibrary.org/obo/ECAO_0109790 presumptive postoral arm neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron A neuronal progenitor cell present in the epidermis of a postoral arm. http://purl.obolibrary.org/obo/ECAO_0109800 presumptive oral hood neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron A neuronal progenitor cell present in the epidermis of the oral hood. http://purl.obolibrary.org/obo/ECAO_0109810 postoral arm neuron http://purl.obolibrary.org/obo/ECAO_0104800 larval neuron A neuron that is located in the postoral arm ectoderm outside the ciliary band. http://purl.obolibrary.org/obo/ECAO_0109820 oral hood neuron http://purl.obolibrary.org/obo/ECAO_0104800 larval neuron A neuron that is located in the oral hood. http://purl.obolibrary.org/obo/ECAO_0109830 nitric oxide synthase neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron A neuron of which transmission is mediated by nitric oxide. http://purl.obolibrary.org/obo/ECAO_0109840 axon http://purl.obolibrary.org/obo/ECAO_0109350 cellular anatomical entity The long process of a neuron that conducts nerve impulses, usually away from the neural cell body. http://purl.obolibrary.org/obo/ECAO_0109850 neural cell body http://purl.obolibrary.org/obo/ECAO_0109230 cell body The portion of a neuron that includes the nucleus, but excludes cell projections such as axons. http://purl.obolibrary.org/obo/ECAO_0109860 apical organ http://purl.obolibrary.org/obo/ECAO_0104878 neural structure A neural structure that develops from the apical pole domain, above the mouth, and contains neurons. http://purl.obolibrary.org/obo/ECAO_0109870 presumptive oral hood ciliary band http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region A specific embryonic or larval ectodermal territory located on the oral side and that will give rise to the oral hood ciliary band. http://purl.obolibrary.org/obo/ECAO_0109880 ciliary band cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that composes the ciliary band. http://purl.obolibrary.org/obo/ECAO_0109890 oral hood ciliary band cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that composes the oral hood ciliary band. http://purl.obolibrary.org/obo/ECAO_0109900 arm bud ciliary band http://purl.obolibrary.org/obo/ECAO_0107930 presumptive ciliary band The portion of the ciliary band that covers the arm buds. http://purl.obolibrary.org/obo/ECAO_0109910 arm distal tip ciliary band http://purl.obolibrary.org/obo/ECAO_0105480 arm ciliary band The portion of the arm ciliary band that covers the arm distal tip. http://purl.obolibrary.org/obo/ECAO_0109920 arm proximal tip ciliary band http://purl.obolibrary.org/obo/ECAO_0105480 arm ciliary band The portion of the arm ciliary band that covers the arm proximal tip. http://purl.obolibrary.org/obo/ECAO_0109930 arm middle portion ciliary band http://purl.obolibrary.org/obo/ECAO_0105480 arm ciliary band The portion of the arm ciliary band that covers the region of the arm between the distal and proximal tips. http://purl.obolibrary.org/obo/ECAO_0109940 animal presumptive ciliary band http://purl.obolibrary.org/obo/ECAO_0107930 presumptive ciliary band The portion of the presumptive ciliary band that overlaps with the animal pole domain. http://purl.obolibrary.org/obo/ECAO_0109950 vegetal presumtive ciliary band http://purl.obolibrary.org/obo/ECAO_0107930 presumptive ciliary band The portion of the presumptive ciliary band located close to the vegetal pole. http://purl.obolibrary.org/obo/ECAO_0109960 lateral presumptive ciliary band http://purl.obolibrary.org/obo/ECAO_0107930 presumptive ciliary band The portion of the presumptive ciliary located between the animal and the vegetal presumptive ciliary bands. http://purl.obolibrary.org/obo/ECAO_0109970 preoral presumptive ciliary band http://purl.obolibrary.org/obo/ECAO_0107930 presumptive ciliary band In species with two separate ciliary bands, a specific embryonic territory that will develop into the preoral ciliary band. http://purl.obolibrary.org/obo/ECAO_0109980 postoral presumptive ciliary band http://purl.obolibrary.org/obo/ECAO_0107930 presumptive ciliary band In species with two separate ciliary bands, a specific embryonic territory that will develop into the postoral ciliary band. http://purl.obolibrary.org/obo/ECAO_0109990 pre-oral hood http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure A specific ectodermal territory located on the oral side of the embryo or the larva and that will give rise to the oral hood. http://purl.obolibrary.org/obo/ECAO_0110000 arm bud http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure An embryonic region that will develop into an arm. http://purl.obolibrary.org/obo/ECAO_0110010 arm distal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The distal extremity of a larval arm, i.e. the further away from the larval body http://purl.obolibrary.org/obo/ECAO_0110020 arm proximal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The proximal extremity of a larval arm, i.e. the closest to the larval body http://purl.obolibrary.org/obo/ECAO_0110030 arm middle portion http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The portion of a larval arm comprised between the distal and proximal tips of the arm. http://purl.obolibrary.org/obo/ECAO_0110040 arm bud ectoderm http://purl.obolibrary.org/obo/ECAO_0104908 ectoderm The thickened ectodermal region that outlines the arm bud. http://purl.obolibrary.org/obo/ECAO_0110050 arm ectoderm http://purl.obolibrary.org/obo/ECAO_0104908 ectoderm The ectodermal (or epidermal) portion of the arm skin and that does not include the ciliary band. http://purl.obolibrary.org/obo/ECAO_0110060 arm distal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110050 arm ectoderm The ectodermal (or epidermal) that covers the distal arm tip and does not include the ciliary band. http://purl.obolibrary.org/obo/ECAO_0110070 arm proximal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110050 arm ectoderm The ectodermal (or epidermal) that covers the proximal arm tip and does not include the ciliary band. http://purl.obolibrary.org/obo/ECAO_0110080 arm middle portion ectoderm http://purl.obolibrary.org/obo/ECAO_0110050 arm ectoderm The ectodermal (or epidermal) that covers the portion of the arm located between the distal and proximal tips and that does not include the ciliary band. http://purl.obolibrary.org/obo/ECAO_0110090 arm bud skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112340 skeletogenic mesenchyme cell A skeletogenic mesenchyme cell present in the arm bud and that will contribute to the development of a skeletal rod. http://purl.obolibrary.org/obo/ECAO_0110100 skeletal rod distal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The distal tip of a skeletal rod, i.e. the further away from its initiation site. http://purl.obolibrary.org/obo/ECAO_0110110 skeletal rod proximal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The proximal tip of a skeletal rod, i.e. the closest to its initiation site. http://purl.obolibrary.org/obo/ECAO_0110120 skeletal rod middle portion http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The portion of a skeletal rod comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0110130 arm skeletal rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod A skeletal rod supporting an arm. http://purl.obolibrary.org/obo/ECAO_0110140 arm skeletal rod distal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The distal tip of an arm skeletal rod, i.e. the further away from its initiation site and the larval body. http://purl.obolibrary.org/obo/ECAO_0110150 arm skeletal rod proximal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The proximal tip of an arm skeletal rod, i.e. the closest to its initiation site and the larval body. http://purl.obolibrary.org/obo/ECAO_0110160 arm skeletal rod middle portion http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The portion of an arm skeletal rod comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112340 skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a skeletal rod. http://purl.obolibrary.org/obo/ECAO_0110180 skeletal rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a skeletal rod. http://purl.obolibrary.org/obo/ECAO_0110190 skeletal rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a skeletal rod. http://purl.obolibrary.org/obo/ECAO_0110200 skeletal rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of the region of a skeletal rod comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0110210 arm skeletal rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112340 skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of an arm skeletal rod. http://purl.obolibrary.org/obo/ECAO_0110220 arm skeletal rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110210 arm skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of an arm skeletal rod. http://purl.obolibrary.org/obo/ECAO_0110230 arm skeletal rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110210 arm skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of an arm skeletal rod. http://purl.obolibrary.org/obo/ECAO_0110240 arm skeletal rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110210 arm skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of the region of an arm skeletal rod comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0110250 postoral arm bud http://purl.obolibrary.org/obo/ECAO_0110000 arm bud An arm bud that will develop into a postoral arm. http://purl.obolibrary.org/obo/ECAO_0110260 right postoral arm bud http://purl.obolibrary.org/obo/ECAO_0110250 postoral arm bud The arm bud on the right side of the embryo that will develop into a postoral arm. http://purl.obolibrary.org/obo/ECAO_0110270 left postoral arm bud http://purl.obolibrary.org/obo/ECAO_0110250 postoral arm bud The arm bud on the left side of the embryo that will develop into a postoral arm. http://purl.obolibrary.org/obo/ECAO_0110280 postoral arm distal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The distal tip of a postoral arm. http://purl.obolibrary.org/obo/ECAO_0110290 right postoral arm distal tip http://purl.obolibrary.org/obo/ECAO_0110280 postoral arm distal tip The distal tip of a right postoral arm. http://purl.obolibrary.org/obo/ECAO_0110300 left postoral arm distal tip http://purl.obolibrary.org/obo/ECAO_0110280 postoral arm distal tip The distal tip of a left postoral arm. http://purl.obolibrary.org/obo/ECAO_0110310 postoral arm proximal tip http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The proximal tip of a postoral arm. http://purl.obolibrary.org/obo/ECAO_0110320 right postoral arm proximal tip http://purl.obolibrary.org/obo/ECAO_0110310 postoral arm proximal tip The proximal tip of a right postoral arm. http://purl.obolibrary.org/obo/ECAO_0110330 left postoral arm proximal tip http://purl.obolibrary.org/obo/ECAO_0110310 postoral arm proximal tip The proximal tip of a left postoral arm. http://purl.obolibrary.org/obo/ECAO_0110340 postoral arm middle portion http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The middle region of a postoral arm comprised between the distal and proximal tip of the arm. http://purl.obolibrary.org/obo/ECAO_0110350 right postoral arm middle portion http://purl.obolibrary.org/obo/ECAO_0110340 postoral arm middle portion The middle region of a right postoral arm. http://purl.obolibrary.org/obo/ECAO_0110360 left postoral arm middle portion http://purl.obolibrary.org/obo/ECAO_0110340 postoral arm middle portion The middle region of a left postoral arm. http://purl.obolibrary.org/obo/ECAO_0110370 postoral arm bud ectoderm http://purl.obolibrary.org/obo/ECAO_0110040 arm bud ectoderm The portion of the ectoderm that outlines a postoral arm bud. http://purl.obolibrary.org/obo/ECAO_0110380 right postoral arm bud ectoderm http://purl.obolibrary.org/obo/ECAO_0110370 postoral arm bud ectoderm The portion of the ectoderm that outlines a postoral arm bud on the right side of the embryo. http://purl.obolibrary.org/obo/ECAO_0110390 left postoral arm bud ectoderm http://purl.obolibrary.org/obo/ECAO_0110370 postoral arm bud ectoderm The portion of the ectoderm that outlines a postoral arm bud on the left side of the embryo. http://purl.obolibrary.org/obo/ECAO_0110400 postoral arm ectoderm http://purl.obolibrary.org/obo/ECAO_0110050 arm ectoderm The ectoderm (or epidermis) that covers a postoral arm but does not include the ciliary band. http://purl.obolibrary.org/obo/ECAO_0110410 right postoral arm ectoderm http://purl.obolibrary.org/obo/ECAO_0110400 postoral arm ectoderm The ectoderm (or epidermis) that covers a right postoral arm but does not include the ciliary band. http://purl.obolibrary.org/obo/ECAO_0110420 left postoral arm ectoderm http://purl.obolibrary.org/obo/ECAO_0110400 postoral arm ectoderm The ectoderm (or epidermis) that covers a left postoral arm but does not include the ciliary band. http://purl.obolibrary.org/obo/ECAO_0110430 postoral arm distal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110060 arm distal tip ectoderm The portion of a postoral arm ectoderm located at the distal tip of the arm. http://purl.obolibrary.org/obo/ECAO_0110440 right postoral arm distal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110430 postoral arm distal tip ectoderm The postoral arm distal tip ectoderm part of a right postoral arm. http://purl.obolibrary.org/obo/ECAO_0110450 left postoral arm distal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110430 postoral arm distal tip ectoderm The postoral arm distal tip ectoderm part of a left postoral arm. http://purl.obolibrary.org/obo/ECAO_0110460 postoral arm proximal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110070 arm proximal tip ectoderm The portion of a postoral arm ectoderm located at the proximal tip of the arm. http://purl.obolibrary.org/obo/ECAO_0110470 right postoral arm proximal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110460 postoral arm proximal tip ectoderm The postoral arm proximal tip ectoderm part of a right postoral arm. http://purl.obolibrary.org/obo/ECAO_0110480 left postoral arm proximal tip ectoderm http://purl.obolibrary.org/obo/ECAO_0110460 postoral arm proximal tip ectoderm The postoral arm proximal tip ectoderm part of a left postoral arm. http://purl.obolibrary.org/obo/ECAO_0110490 postoral arm middle portion ectoderm http://purl.obolibrary.org/obo/ECAO_0110080 arm middle portion ectoderm The portion of a postoral arm ectoderm located between the distal and proximal tips of the arm. http://purl.obolibrary.org/obo/ECAO_0110500 right postoral arm middle portion ectoderm http://purl.obolibrary.org/obo/ECAO_0110490 postoral arm middle portion ectoderm The postoral arm middle portion ectoderm part of a right postoral arm. http://purl.obolibrary.org/obo/ECAO_0110510 left postoral arm middle portion ectoderm http://purl.obolibrary.org/obo/ECAO_0110490 postoral arm middle portion ectoderm The postoral arm middle portion ectoderm part of a left postoral arm. http://purl.obolibrary.org/obo/ECAO_0110520 postoral rod distal tip http://purl.obolibrary.org/obo/ECAO_0110140 arm skeletal rod distal tip The distal tip of a postoral rod. http://purl.obolibrary.org/obo/ECAO_0110530 right postoral rod distal tip http://purl.obolibrary.org/obo/ECAO_0110520 postoral rod distal tip The distal tip of a right postoral rod. http://purl.obolibrary.org/obo/ECAO_0110540 left postoral rod distal tip http://purl.obolibrary.org/obo/ECAO_0110520 postoral rod distal tip The distal tip of a left postoral rod. http://purl.obolibrary.org/obo/ECAO_0110550 postoral rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110150 arm skeletal rod proximal tip The proximal tip of a postoral rod. http://purl.obolibrary.org/obo/ECAO_0110560 right postoral rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110550 postoral rod proximal tip The proximal tip of a right postoral rod. http://purl.obolibrary.org/obo/ECAO_0110570 left postoral rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110550 postoral rod proximal tip The proximal tip of a left postoral rod. http://purl.obolibrary.org/obo/ECAO_0110580 postoral rod middle portion http://purl.obolibrary.org/obo/ECAO_0110160 arm skeletal rod middle portion The middle region of a postoral rod comprised between the distal and proximal tip of the rod. http://purl.obolibrary.org/obo/ECAO_0110590 right postoral rod middle portion http://purl.obolibrary.org/obo/ECAO_0110580 postoral rod middle portion The middle region of a right postoral rod. http://purl.obolibrary.org/obo/ECAO_0110600 left postoral rod middle portion http://purl.obolibrary.org/obo/ECAO_0110580 postoral rod middle portion The middle region of a left postoral rod. http://purl.obolibrary.org/obo/ECAO_0110610 postoral rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110210 arm skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a postoral rod. http://purl.obolibrary.org/obo/ECAO_0110620 right postoral rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110610 postoral rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a right postoral rod. http://purl.obolibrary.org/obo/ECAO_0110630 left postoral rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110610 postoral rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a left postoral rod. http://purl.obolibrary.org/obo/ECAO_0110640 postoral rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110220 arm skeletal rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a postoral rod. http://purl.obolibrary.org/obo/ECAO_0110650 right postoral rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110640 postoral rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a right postoral rod. http://purl.obolibrary.org/obo/ECAO_0110660 left postoral rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110640 postoral rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a left postoral rod. http://purl.obolibrary.org/obo/ECAO_0110670 postoral rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110230 arm skeletal rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a postoral rod. http://purl.obolibrary.org/obo/ECAO_0110680 right postoral rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110670 postoral rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a right postoral rod. http://purl.obolibrary.org/obo/ECAO_0110690 left postoral rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110670 postoral rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a left postoral rod. http://purl.obolibrary.org/obo/ECAO_0110700 postoral rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110240 arm skeletal rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a postoral rod, comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0110710 right postoral rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110700 postoral rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a right postoral rod. http://purl.obolibrary.org/obo/ECAO_0110720 left postoral rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110700 postoral rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a left postoral rod. http://purl.obolibrary.org/obo/ECAO_0110730 anonymous rod distal tip http://purl.obolibrary.org/obo/ECAO_0110100 skeletal rod distal tip The distal tip of an anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110740 right anonymous rod distal tip http://purl.obolibrary.org/obo/ECAO_0110730 anonymous rod distal tip The distal tip of a right anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110750 left anonymous rod distal tip http://purl.obolibrary.org/obo/ECAO_0110730 anonymous rod distal tip The distal tip of a left anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110760 anonymous rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110110 skeletal rod proximal tip The proximal tip of an anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110770 right anonymous rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110760 anonymous rod proximal tip The proximal tip of a right anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110780 left anonymous rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110760 anonymous rod proximal tip The proximal tip of a left anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110790 anonymous rod middle portion http://purl.obolibrary.org/obo/ECAO_0110120 skeletal rod middle portion The middle region of an anonymous rod comprised between the distal and proximal tip of the rod. http://purl.obolibrary.org/obo/ECAO_0110800 right anonymous rod middle portion http://purl.obolibrary.org/obo/ECAO_0110790 anonymous rod middle portion The middle region of a right anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110810 left anonymous rod middle portion http://purl.obolibrary.org/obo/ECAO_0110790 anonymous rod middle portion The middle region of a left anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110820 anonymous rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of an anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110830 right anonymous rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110820 anonymous rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a right anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110840 left anonymous rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110820 anonymous rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a left anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110850 anonymous rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of an anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110860 right anonymous rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110850 anonymous rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a right anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110870 left anonymous rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110850 anonymous rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a left anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110880 anonymous rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of an anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110890 right anonymous rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110880 anonymous rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a right anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110900 left anonymous rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110880 anonymous rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a left anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110910 anonymous rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110200 skeletal rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of an anonymous rod, comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0110920 right anonymous rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110910 anonymous rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a right anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110930 left anonymous rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110910 anonymous rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a left anonymous rod. http://purl.obolibrary.org/obo/ECAO_0110940 anterolateral rod distal tip http://purl.obolibrary.org/obo/ECAO_0110140 arm skeletal rod distal tip The distal tip of an anterolateral rod, i.e. away from its connection with the dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0110950 right anterolateral rod distal tip http://purl.obolibrary.org/obo/ECAO_0110940 anterolateral rod distal tip The distal tip of a right anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0110960 left anterolateral rod distal tip http://purl.obolibrary.org/obo/ECAO_0110940 anterolateral rod distal tip The distal tip of a left anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0110970 anterolateral rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110140 arm skeletal rod distal tip The proximal tip of an anterolateral rod, i.e. in connection with the dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0110980 right anterolateral rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110970 anterolateral rod proximal tip The proximal tip of a right anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0110990 left anterolateral rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110970 anterolateral rod proximal tip The proximal tip of a left anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111000 anterolateral rod middle portion http://purl.obolibrary.org/obo/ECAO_0110140 arm skeletal rod distal tip The middle portion of an anterolateral rod, i.e., comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111010 right anterolateral rod middle portion http://purl.obolibrary.org/obo/ECAO_0111000 anterolateral rod middle portion The middle portion of a right anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111020 left anterolateral rod middle portion http://purl.obolibrary.org/obo/ECAO_0111000 anterolateral rod middle portion The middle portion of a left anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111030 anterolateral rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110210 arm skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of an anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111040 right anterolateral rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111030 anterolateral rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a right anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111050 left anterolateral rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111030 anterolateral rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a left anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111060 anterolateral rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110220 arm skeletal rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of an anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111070 right anterolateral rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111060 anterolateral rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a right anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111080 left anterolateral rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111060 anterolateral rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a left anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111090 anterolateral rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110230 arm skeletal rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of an anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111100 right anterolateral rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111090 anterolateral rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a right anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111110 left anterolateral rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111090 anterolateral rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a left anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111120 anterolateral rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110240 arm skeletal rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of an anterolateral rod, comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111130 right anterolateral rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111120 anterolateral rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a right anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111140 left anterolateral rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111120 anterolateral rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a left anterolateral rod. http://purl.obolibrary.org/obo/ECAO_0111150 dorsoventral connecting rod animal tip http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element The portion of a dorsoventral connecting rod that bends (or branches) to give rise to the anterolateral rod and in some echinoid species to the recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111160 right dorsoventral connecting rod animal tip http://purl.obolibrary.org/obo/ECAO_0111150 dorsoventral connecting rod animal tip The animal tip of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111170 left dorsoventral connecting rod animal tip http://purl.obolibrary.org/obo/ECAO_0111150 dorsoventral connecting rod animal tip The animal tip of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111180 dorsoventral connecting rod distal tip http://purl.obolibrary.org/obo/ECAO_0110100 skeletal rod distal tip The distal tip of a dorsoventral connecting rod, i.e. in connection with the anterolateral rod and in some echinoid species the recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111190 right dorsoventral connecting rod distal tip http://purl.obolibrary.org/obo/ECAO_0111180 dorsoventral connecting rod distal tip The distal tip of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111200 left dorsoventral connecting rod distal tip http://purl.obolibrary.org/obo/ECAO_0111180 dorsoventral connecting rod distal tip The distal tip of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111210 dorsoventral connecting rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110110 skeletal rod proximal tip The proximal tip of a dorsoventral connecting rod, i.e. in connection with the anonymous and ventral transverse rods. http://purl.obolibrary.org/obo/ECAO_0111220 right dorsoventral connecting rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111210 dorsoventral connecting rod proximal tip The proximal tip of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111230 left dorsoventral connecting rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111210 dorsoventral connecting rod proximal tip The proximal tip of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111240 dorsoventral connecting rod middle portion http://purl.obolibrary.org/obo/ECAO_0110120 skeletal rod middle portion The middle portion of a dorsoventral connecting rod, i.e., comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111250 right dorsoventral connecting rod middle portion http://purl.obolibrary.org/obo/ECAO_0111240 dorsoventral connecting rod middle portion The middle portion of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111260 left dorsoventral connecting rod middle portion http://purl.obolibrary.org/obo/ECAO_0111240 dorsoventral connecting rod middle portion The middle portion of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111270 dorsoventral connecting rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111280 right dorsoventral connecting rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111270 dorsoventral connecting rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111290 left dorsoventral connecting rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111270 dorsoventral connecting rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111300 dorsoventral connecting rod animal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of the bended portion of a dorsoventral connecting rod, before this portion elongates and becomes an anterolateral rod or in some echinoid species branches into a anterolateral and a recurrent rods. http://purl.obolibrary.org/obo/ECAO_0111310 right dorsoventral connecting rod animal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111300 dorsoventral connecting rod animal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the animal tip of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111320 left dorsoventral connecting rod animal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111300 dorsoventral connecting rod animal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the animal tip of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111330 dorsoventral connecting rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110180 skeletal rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a dorsoventral connecting rod, before its bended portion. http://purl.obolibrary.org/obo/ECAO_0111340 right dorsoventral connecting rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111330 dorsoventral connecting rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111350 left dorsoventral connecting rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111330 dorsoventral connecting rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111360 dorsoventral connecting rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110190 skeletal rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a dorsoventral connecting rod, in the vicinity of an anonymous and ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111370 right dorsoventral connecting rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111360 dorsoventral connecting rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111380 left dorsoventral connecting rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111360 dorsoventral connecting rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111390 dorsoventral connecting rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110200 skeletal rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a dorsoventral connecting rod, comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111400 right dorsoventral connecting rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111390 dorsoventral connecting rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a right dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111410 left dorsoventral connecting rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111390 dorsoventral connecting rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a left dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111420 ventral transverse rod distal tip http://purl.obolibrary.org/obo/ECAO_0110100 skeletal rod distal tip The distal tip of a ventral transverse rod, i.e. away from the connection with the dorsoventral connecting and anonymous rods. http://purl.obolibrary.org/obo/ECAO_0111430 right ventral transverse rod distal tip http://purl.obolibrary.org/obo/ECAO_0111180 dorsoventral connecting rod distal tip The distal tip of a right ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111440 left ventral transverse rod distal tip http://purl.obolibrary.org/obo/ECAO_0111180 dorsoventral connecting rod distal tip The distal tip of a left ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111450 ventral transverse rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110110 skeletal rod proximal tip The proximal tip of a ventral transverse rod, i.e. in connection with the dorsoventral connecting and anonymous rods. http://purl.obolibrary.org/obo/ECAO_0111460 right ventral transverse rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111210 dorsoventral connecting rod proximal tip The proximal tip of a right ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111470 left ventral transverse rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111210 dorsoventral connecting rod proximal tip The proximal tip of a left ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111480 ventral transverse rod middle portion http://purl.obolibrary.org/obo/ECAO_0110120 skeletal rod middle portion The middle portion of a ventral transverse rod, i.e., comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111490 right ventral transverse rod middle portion http://purl.obolibrary.org/obo/ECAO_0111240 dorsoventral connecting rod middle portion The middle portion of a right ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111500 left ventral transverse rod middle portion http://purl.obolibrary.org/obo/ECAO_0111240 dorsoventral connecting rod middle portion The middle portion of a left ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111510 ventral transverse rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111520 right ventral transverse rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111510 ventral transverse rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a right ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111530 left ventral transverse rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111510 ventral transverse rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a left ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111540 ventral transverse rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111550 right ventral transverse rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111540 ventral transverse rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a right ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111560 left ventral transverse rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111540 ventral transverse rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a left ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111570 ventral transverse rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111580 right ventral transverse rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111570 ventral transverse rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a right ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111590 left ventral transverse rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111570 ventral transverse rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a left ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111600 ventral transverse rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110200 skeletal rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a ventral transverse rod, comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111610 right ventral transverse rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111600 ventral transverse rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a right ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111620 left ventral transverse rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111600 ventral transverse rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a left ventral transverse rod. http://purl.obolibrary.org/obo/ECAO_0111630 body rod distal tip http://purl.obolibrary.org/obo/ECAO_0110100 skeletal rod distal tip The growing tip of a body rod as it extends dorsally away from an anonymous rod. http://purl.obolibrary.org/obo/ECAO_0111640 right body rod distal tip http://purl.obolibrary.org/obo/ECAO_0111630 body rod distal tip The distal tip of a right body rod. http://purl.obolibrary.org/obo/ECAO_0111650 left body rod distal tip http://purl.obolibrary.org/obo/ECAO_0111630 body rod distal tip The distal tip of a left body rod. http://purl.obolibrary.org/obo/ECAO_0111660 body rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110110 skeletal rod proximal tip The proximal tip of a body rod, i.e. in connection with an anonymous rod. http://purl.obolibrary.org/obo/ECAO_0111670 right body rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111660 body rod proximal tip The proximal tip of a right body rod. http://purl.obolibrary.org/obo/ECAO_0111680 left body rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111660 body rod proximal tip The proximal tip of a left body rod. http://purl.obolibrary.org/obo/ECAO_0111690 body rod middle portion http://purl.obolibrary.org/obo/ECAO_0110120 skeletal rod middle portion The middle portion of a body rod, i.e., comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111700 right body rod middle portion http://purl.obolibrary.org/obo/ECAO_0111690 body rod middle portion The middle portion of a right body rod. http://purl.obolibrary.org/obo/ECAO_0111710 left body rod middle portion http://purl.obolibrary.org/obo/ECAO_0111690 body rod middle portion The middle portion of a left body rod. http://purl.obolibrary.org/obo/ECAO_0111720 body rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a body rod. http://purl.obolibrary.org/obo/ECAO_0111730 right body rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111720 body rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a right body rod. http://purl.obolibrary.org/obo/ECAO_0111740 left body rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111720 body rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a left body rod. http://purl.obolibrary.org/obo/ECAO_0111750 body rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a body rod. http://purl.obolibrary.org/obo/ECAO_0111760 right body rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111750 body rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a right body rod. http://purl.obolibrary.org/obo/ECAO_0111770 left body rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111750 body rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a left body rod. http://purl.obolibrary.org/obo/ECAO_0111780 body rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a body rod. http://purl.obolibrary.org/obo/ECAO_0111790 right body rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111780 body rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a right body rod. http://purl.obolibrary.org/obo/ECAO_0111800 left body rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111780 body rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a left body rod. http://purl.obolibrary.org/obo/ECAO_0111810 body rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110200 skeletal rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a body rod, comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111820 right body rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111810 body rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a right body rod. http://purl.obolibrary.org/obo/ECAO_0111830 left body rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111810 body rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a left body rod. http://purl.obolibrary.org/obo/ECAO_0111840 scheitel skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a scheitel. http://purl.obolibrary.org/obo/ECAO_0111850 recurrent rod distal tip http://purl.obolibrary.org/obo/ECAO_0110100 skeletal rod distal tip The distal tip of a recurrent rod, i.e. in connection with a dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111860 right recurrent rod distal tip http://purl.obolibrary.org/obo/ECAO_0111850 recurrent rod distal tip The distal tip of a right recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111870 left recurrent rod distal tip http://purl.obolibrary.org/obo/ECAO_0111850 recurrent rod distal tip The distal tip of a left recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111880 recurrent rod proximal tip http://purl.obolibrary.org/obo/ECAO_0110110 skeletal rod proximal tip The proximal tip of a recurrent rod, i.e. away from a dorsoventral connecting rod. http://purl.obolibrary.org/obo/ECAO_0111890 right recurrent rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111880 recurrent rod proximal tip The proximal tip of a right recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111900 left recurrent rod proximal tip http://purl.obolibrary.org/obo/ECAO_0111880 recurrent rod proximal tip The proximal tip of a left recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111910 recurrent rod middle portion http://purl.obolibrary.org/obo/ECAO_0110120 skeletal rod middle portion The middle portion of a recurrent rod, i.e., comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0111920 right recurrent rod middle portion http://purl.obolibrary.org/obo/ECAO_0111910 recurrent rod middle portion The middle portion of a right recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111930 left recurrent rod middle portion http://purl.obolibrary.org/obo/ECAO_0111910 recurrent rod middle portion The middle portion of a left recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111940 recurrent rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111950 right recurrent rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111940 recurrent rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a right recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111960 left recurrent rod skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111940 recurrent rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell part of a left recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111970 recurrent rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111980 right recurrent rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111970 recurrent rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a right recurrent rod. http://purl.obolibrary.org/obo/ECAO_0111990 left recurrent rod distal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0111970 recurrent rod distal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the distal tip of a left recurrent rod. http://purl.obolibrary.org/obo/ECAO_0112000 recurrent rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110170 skeletal rod skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a recurrent rod. http://purl.obolibrary.org/obo/ECAO_0112010 right recurrent rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112000 recurrent rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a right recurrent rod. http://purl.obolibrary.org/obo/ECAO_0112020 left recurrent rod proximal tip skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112000 recurrent rod proximal tip skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the proximal tip of a left recurrent rod. http://purl.obolibrary.org/obo/ECAO_0112030 recurrent rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0110200 skeletal rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a recurrent rod, comprised between the distal and proximal tips of the rod. http://purl.obolibrary.org/obo/ECAO_0112040 right recurrent rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112030 recurrent rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a right recurrent rod. http://purl.obolibrary.org/obo/ECAO_0112050 left recurrent rod middle portion skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112030 recurrent rod middle portion skeletogenic mesenchyme cell A skeletogenic mesenchyme cell composing the middle portion of a left recurrent rod. http://purl.obolibrary.org/obo/ECAO_0112060 enoderm cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell part of the endoderm germ layer. http://purl.obolibrary.org/obo/ECAO_0112070 vegetal tier 1 endoderm http://purl.obolibrary.org/obo/ECAO_0106010 presumptive endoderm The presumptive endoderm that develops specifically from the cells of the vegetal tier 1. http://purl.obolibrary.org/obo/ECAO_0112080 vegetal tier 2 endoderm http://purl.obolibrary.org/obo/ECAO_0106010 presumptive endoderm The presumptive endoderm that develops specifically from the cells of the vegetal tier 2. http://purl.obolibrary.org/obo/ECAO_0112090 embryonic endoderm http://purl.obolibrary.org/obo/ECAO_0106020 endoderm The endoderm that is specifically present in an embryo. http://purl.obolibrary.org/obo/ECAO_0112100 larval endoderm http://purl.obolibrary.org/obo/ECAO_0106020 endoderm The endoderm that is specifically present in a larva. http://purl.obolibrary.org/obo/ECAO_0112110 pre-metamorphic organism endoderm http://purl.obolibrary.org/obo/ECAO_0106020 endoderm The endoderm that is specifically present in an embryo post-gastrulation and a larva but not in an adult. http://purl.obolibrary.org/obo/ECAO_0112120 archenteron tip http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The anterior territory of the archenteron. http://purl.obolibrary.org/obo/ECAO_0112130 archenteron wall http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure The layer of cells that form the archenteron, but at the level of its anterior tip and that of the blastopore. http://purl.obolibrary.org/obo/ECAO_0112140 middle hindgut http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The middle portion of the hindgut, between its anterior and posterior portions. http://purl.obolibrary.org/obo/ECAO_0112150 middle midgut http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The middle portion of the midgut, between its anterior and posterior portions. http://purl.obolibrary.org/obo/ECAO_0112160 middle foregut http://purl.obolibrary.org/obo/ECAO_0109080 embryonic region The middle portion of the foregut, between its anterior and posterior portions. http://purl.obolibrary.org/obo/ECAO_0112170 esophagus http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element The anterior end of the animal digestive tract that connects the mouth to the stomach. http://purl.obolibrary.org/obo/ECAO_0112180 stomach http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element The central region of the animal digestive tract that serves as a digestive organ. http://purl.obolibrary.org/obo/ECAO_0112190 intestine http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element The posterior region of the animal digestive tract that extends from the stomach to the anus. http://purl.obolibrary.org/obo/ECAO_0112200 coelomic evagination http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure The outpocketing of the mesoderm constituting the tip of the archenteron and forming a bilobed bag (or pouch) lying on the top of the archenteron roof. http://purl.obolibrary.org/obo/ECAO_0112210 coelomic pouch http://purl.obolibrary.org/obo/ECAO_0106770 coelom A mesodermally lined pouch (or pocket) lying between the anterior tip of the archenteron and the outer body wall. http://purl.obolibrary.org/obo/ECAO_0112220 constriction http://purl.obolibrary.org/obo/ECAO_0109000 anatomical element A narrowing (or shrinking) within a tissue or organ to delineate different regions with different fates. http://purl.obolibrary.org/obo/ECAO_0112230 coelomic constriction http://purl.obolibrary.org/obo/ECAO_0112220 constriction A constriction taking place at the level of a coelom. It can either separate the coelom from the archenteron or lead to the compartmentalization of the coelom into distinct regions. http://purl.obolibrary.org/obo/ECAO_0112240 anterior coelomic pouch http://purl.obolibrary.org/obo/ECAO_0112210 coelomic pouch In species with a posterior enterocoel, the anterior coelomic pouch is the one that develops from the unpaired coelomic evaginations at the tip of the archenteron. http://purl.obolibrary.org/obo/ECAO_0112250 larval epidermis http://purl.obolibrary.org/obo/ECAO_0104110 tissue An epidermal tissue present in the larva. http://purl.obolibrary.org/obo/ECAO_0112260 ventral epiderms http://purl.obolibrary.org/obo/ECAO_0106828 larval epithelium The epidermal tissue of the larva that surrounds the mouth. http://purl.obolibrary.org/obo/ECAO_0112270 dorsal epidermis http://purl.obolibrary.org/obo/ECAO_0106828 larval epithelium The epidermal tissue of the larva that is on the side opposite to the mouth. http://purl.obolibrary.org/obo/ECAO_0112280 mesenchyme http://purl.obolibrary.org/obo/ECAO_0104110 tissue A tissue composed of mesenchymal cells. http://purl.obolibrary.org/obo/ECAO_0112290 mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that has undergone epithelial to mesenchymal transition and is capable of migration. http://purl.obolibrary.org/obo/ECAO_0112300 presumptive skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0106200 presumptive mesoderm The region of the early embryo that will develop into skeletogenic mesoderm. http://purl.obolibrary.org/obo/ECAO_0112310 skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0104110 tissue The subset of the mesoderm germ layer that will exclusively give rise to the endoskeleton. http://purl.obolibrary.org/obo/ECAO_0112320 skeletogenic mesoderm cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that has the potential of developing into a skeletogenic mesenchyme cell (or skeletal cell). http://purl.obolibrary.org/obo/ECAO_0112330 skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104110 tissue The portion of the mesenchyme tissue that constitutes the endoskeleton. http://purl.obolibrary.org/obo/ECAO_0112340 skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell that after having undergone epithelial to mesenchymal transition participates in constituting the endoskeleton. http://purl.obolibrary.org/obo/ECAO_0112350 syncytial filipodial cable http://purl.obolibrary.org/obo/ECAO_0104110 tissue A filopodial cable that participates in the establishment of a syncytium. http://purl.obolibrary.org/obo/ECAO_0112360 chain of skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure A straight, syncitial network that either links the two ventrolateral skeletogenic mesenchyme clusters within the subequatorial skeletogenic mesenchyme ring or extends from the ventrolateral skeletogenic mesenchyme clusters towards the animal pole domain. http://purl.obolibrary.org/obo/ECAO_0112370 oral chain of skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112360 chain of skeletogenic mesenchyme cell The chain of skeletogenic mesenchyme cell that within the subequatorial skeletogenic mesenchyme ring links the two ventrolateral skeletogenic mesenchyme clusters on the oral side of the embryo. The ventral transverse rods will be deposited along this cellular strand. http://purl.obolibrary.org/obo/ECAO_0112380 aboral chain of skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112360 chain of skeletogenic mesenchyme cell The chain of skeletogenic mesenchyme cell that within the subequatorial skeletogenic mesenchyme ring links the two ventrolateral skeletogenic mesenchyme clusters on the aboral side of the embryo. The body rods will be deposited along this cellular strand. http://purl.obolibrary.org/obo/ECAO_0112390 skeletogenic mesenchyme cluster http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure A cluster of skeletogenic mesenchyme cells that aggregates before any calcification event whether in the embryo, the larva, or the adult. http://purl.obolibrary.org/obo/ECAO_0112400 lateral chain of skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112360 chain of skeletogenic mesenchyme cell A chain of skeletogenic mesenchyme cell that extends from a ventrolateral cluster toward the animal pole. A dorsoventral connecting rod will be deposited along this cellular strand. http://purl.obolibrary.org/obo/ECAO_0112410 right lateral chain of skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0106320 lateral chain of skeletogenic mesenchyme The lateral chain that forms on the right side of the embryo from the right ventrolateral cluster. http://purl.obolibrary.org/obo/ECAO_0112420 left lateral chain of skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0106320 lateral chain of skeletogenic mesenchyme The lateral chain that forms on the left side of the embryo from the left ventrolateral cluster. http://purl.obolibrary.org/obo/ECAO_0112430 triradiate spicule http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element A skeletal, calcified structure composed of three elongated skeletal rods. http://purl.obolibrary.org/obo/ECAO_0112440 ventrolateral spicule granule http://purl.obolibrary.org/obo/ECAO_0105630 spicule granule A spicule granule that forms within a ventrolateral cluster of skeletogenic mesenchyme cells. http://purl.obolibrary.org/obo/ECAO_0112450 right ventrolateral spicule granule http://purl.obolibrary.org/obo/ECAO_0112440 ventrolateral spicule granule A ventrolateral spicule granule that forms on the right side of the embryo. http://purl.obolibrary.org/obo/ECAO_0112460 left ventrolateral spicule granule http://purl.obolibrary.org/obo/ECAO_0112440 ventrolateral spicule granule A ventrolateral spicule granule that forms on the left side of the embryo. http://purl.obolibrary.org/obo/ECAO_0112470 ventrolateral triradiate spicule rudiment http://purl.obolibrary.org/obo/ECAO_0112440 ventrolateral spicule granule A triradiate spicule rudiment that forms within a ventrolateral cluster of skeletogenic mesenchyme cells. http://purl.obolibrary.org/obo/ECAO_0112480 presumptive non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0106200 presumptive mesoderm An embryonic, larval or adult region that will develop into non-skeletogenic mesoderm and/or mesenchyme derivatives. http://purl.obolibrary.org/obo/ECAO_0112490 non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0106210 mesoderm The subset of the mesoderm germ layer that will give rise to all mesoderm tissue derivatives but the endoskeleton; e.g. muscles, coeloms, pigment cells, blastocoelar cells. http://purl.obolibrary.org/obo/ECAO_0112500 non-skeletogenic mesoderm cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A cell part of the mesoderm germ layer subset that will give rise to all mesoderm tissue derivatives but the endoskeleton; e.g. muscles, coeloms, pigment cells, blastocoelar cells. http://purl.obolibrary.org/obo/ECAO_0112510 non-skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0112280 mesenchyme All mesenchyme present in the embryo, larva, or adult but that does not constitute the endoskeleton. http://purl.obolibrary.org/obo/ECAO_0112520 non-skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104030 cell A mesenchymal cell that participates in the elaboration of all mesenchyme derivatives but the endoskeleton; e.g. pigment cells, blastocoelar cells. http://purl.obolibrary.org/obo/ECAO_0112530 vegetal tier 2 non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0108070 presumptive embryonic non-skeletogenic mesoderm The presumptive embryonic non-skeletogenic mesoderm that derives from the vegetal 2 tier cells and not from the small micromere descendants. http://purl.obolibrary.org/obo/ECAO_0112540 embryonic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112290 mesenchyme cell In echinoderms with no embryonic endoskeleton, all embryonic cells that have undergone an epithelial-to-mesenchymal transition and will participate in the elaboration of non-skeletogenic mesoderm derivatives; e.g. pigment cells, blastocoelar cells. http://purl.obolibrary.org/obo/ECAO_0112550 larval mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0112290 mesenchyme cell In echinoderms with no larval endoskeleton, all larval mesenchyme cells that participate in the elaboration of non-skeletogenic mesoderm derivatives; e.g. pigment cells, blastocoelar cells. http://purl.obolibrary.org/obo/ECAO_0112560 oral presumptive non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0108070 presumptive embryonic non-skeletogenic mesoderm The presumptive embryonic non-skeletogenic mesoderm that in the vegetal plate is on the oral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0112570 aboral presumptive non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0108070 presumptive embryonic non-skeletogenic mesoderm The presumptive embryonic non-skeletogenic mesoderm that in the vegetal plate is on the aboral side of the embryo. http://purl.obolibrary.org/obo/ECAO_0112580 immune cell http://purl.obolibrary.org/obo/ECAO_0112290 mesenchyme cell A cell of the immune system that is involved in protecting the body against infectious disease and foreign invaders. http://purl.obolibrary.org/obo/ECAO_0112590 phagocytic filopodial cell http://purl.obolibrary.org/obo/ECAO_0106510 filopodial cell The subset of the filopodial cells that are phagocytic and express the immune effector gene 185/333. http://purl.obolibrary.org/obo/ECAO_0112600 sphincter primordium http://purl.obolibrary.org/obo/ECAO_0112220 constriction An initial constriction within the archenteron marking where a sphincter will form. http://purl.obolibrary.org/obo/ECAO_0112610 pyloric sphincter primordium http://purl.obolibrary.org/obo/ECAO_0112600 sphincter primordium The initial constriction within the archenteron that will develop into the pyloric sphincter and separates the midgut and hindgut. http://purl.obolibrary.org/obo/ECAO_0112620 cardiac sphincter primordium http://purl.obolibrary.org/obo/ECAO_0112600 sphincter primordium The initial constriction within the archenteron that will develop into the cardiac sphincter and separates the foregut and the midgut. http://purl.obolibrary.org/obo/ECAO_0112630 anal sphincter primordium http://purl.obolibrary.org/obo/ECAO_0112600 sphincter primordium The initial constriction at the posterior end of the archenteron (i.e. at the level of the blastopore) that will develop into the anal sphincter. http://purl.obolibrary.org/obo/ECAO_0112640 sphincter cell http://purl.obolibrary.org/obo/ECAO_0108110 muscle cell A cell that is part of a sphincter. http://purl.obolibrary.org/obo/ECAO_0112650 pyloric sphincter cell http://purl.obolibrary.org/obo/ECAO_0112640 sphincter cell A cell that is part of a pyloric sphincter. http://purl.obolibrary.org/obo/ECAO_0112660 cardiac sphincter cell http://purl.obolibrary.org/obo/ECAO_0112640 sphincter cell A cell that is part of a cardiac sphincter. http://purl.obolibrary.org/obo/ECAO_0112670 anal sphincter cell http://purl.obolibrary.org/obo/ECAO_0112640 sphincter cell A cell that is part of an anal sphincter. http://purl.obolibrary.org/obo/ECAO_0000135 stage 1 http://purl.obolibrary.org/obo/BFO_0000003 occurrent Fertilization has occurred but the zygote has not divided (1-cell stage). http://purl.obolibrary.org/obo/ECAO_0000155 stage 2 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 2 cells (2-cell stage). http://purl.obolibrary.org/obo/ECAO_0000165 stage 3 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 4 cells (4-cell stage). http://purl.obolibrary.org/obo/ECAO_0000175 stage 4 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 8 cells (8-cell stage). http://purl.obolibrary.org/obo/ECAO_0000185 stage 5 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 16 cells (16-cell stage). http://purl.obolibrary.org/obo/ECAO_0000195 stage 6 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 28-32 cells (includes 28- and 32-cell stages). http://purl.obolibrary.org/obo/ECAO_0000215 stage 7 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 56-64 cells (includes 56-, 60-, and 64-cell stages). http://purl.obolibrary.org/obo/ECAO_0000255 stage 8 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is an early blastula (early blastula stage). http://purl.obolibrary.org/obo/ECAO_0000265 stage 9 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is a mid-blastula (includes mid-blastula and motile blastula stages). http://purl.obolibrary.org/obo/ECAO_0000275 stage 10 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is a late blastula, it is still spherical, and the vegetal plate has not formed (late blastula stage). http://purl.obolibrary.org/obo/ECAO_0000284 stage 11 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo, whether or not hatched from the fertilization envelope, has formed a vegetal plate but gastrulation has not begun (vegetal plate stage). http://purl.obolibrary.org/obo/ECAO_0000286 stage 12 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has hatched from the fertilization envelope and is undergoing the earliest cell movements of gastrulation (includes early, mid-, and late mesenchyme blastula episodes and blastopore formation stage). http://purl.obolibrary.org/obo/ECAO_0000385 stage 13 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is undergoing the first phase of archenteron extension (early gastrula stage). http://purl.obolibrary.org/obo/ECAO_0000395 stage 14 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is undergoing the middle phase of archenteron extension (mid-gastrula stage). http://purl.obolibrary.org/obo/ECAO_0000405 stage 15 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is undergoing the last phase of archenteron extension (late gastrula stage). http://purl.obolibrary.org/obo/ECAO_0000422 stage 16 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has completed archenteron elongation and mesenchyme cell ingression is complete (includes early prism and early organogenesis stages). http://purl.obolibrary.org/obo/ECAO_0000424 stage 17 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has paired coelomic evaginations at the tip of the archenteron but lacks a stomodeal invagination and gut constrictions (includes late prism and mid-organogenesis stages). http://purl.obolibrary.org/obo/ECAO_0000426 stage 18 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has paired coelomic pouches along with a stomodeal invagination and gut constrictions (includes late and very late organogenesis stages). http://purl.obolibrary.org/obo/ECAO_0000428 stage 19 http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has an open mouth (open mouth stage). http://purl.obolibrary.org/obo/GO_0140001 morula formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/NBO_0000001 body part movement http://purl.obolibrary.org/obo/NBO_0000338 kinesthetic behavior A change of place or position of part of an organism that does not involve the entire organism [NBO:SMAC] http://purl.obolibrary.org/obo/NBO_0000007 mouth movement http://purl.obolibrary.org/obo/NBO_0000001 body part movement The act of moving any of the tissues and hard structures surrounding the mouth other than teeth, jaws or filter structures [NBO:AC] http://purl.obolibrary.org/obo/NBO_0000338 kinesthetic behavior http://purl.obolibrary.org/obo/NBO_0000313 behavior process "Movement behavior of the body or its parts." http://purl.obolibrary.org/obo/NBO_0001786 regulation of behavior http://purl.obolibrary.org/obo/NBO_0000313 behavior process "Any process that modulates the frequency, rate or extent of behavior, the specific actions or reactions of an organism in response to external or internal stimuli." [GO:0050795] http://purl.obolibrary.org/obo/GO_1905955 negative regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_1905956 positive regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_0090741 pigment granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane Any membrane that is part of a pigment granule. http://purl.obolibrary.org/obo/CL_0009063 enteroendocrine cell of anorectum http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An enteroendocrine cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_4028001 pulmonary capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell Any capillary endothelial cell that is part of a lung. http://purl.obolibrary.org/obo/CL_4023072 brain vascular cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A cell that is part of the brain vasculature. http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the intestinal serosa. http://purl.obolibrary.org/obo/UBERON_0035118 material entity in digestive tract http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included. http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat The sum of epicardial and paracardial fat deposits. http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Any fat deposit surrounding a visceral organ. http://purl.obolibrary.org/obo/UBERON_0036146 cardiopharyngeal field http://purl.obolibrary.org/obo/UBERON_0007688 anlage An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. http://purl.obolibrary.org/obo/UBERON_0034947 gas in respiratory system http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas Any portion of gas located in a part of the respiratory system. http://purl.obolibrary.org/obo/UBERON_0035159 entire surface of organism http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface. http://purl.obolibrary.org/obo/GO_0110011 regulation of basement membrane organization http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. http://purl.obolibrary.org/obo/GO_0140354 lipid import into cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/CL_0008034 mural cell http://purl.obolibrary.org/obo/CL_4033054 perivascular cell Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation. http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell http://purl.obolibrary.org/obo/CL_0008034 mural cell Any vascular associated smooth muscle cell that is part of some microcirculatory vessel. http://purl.obolibrary.org/obo/CL_0017502 acidophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain. http://purl.obolibrary.org/obo/CL_0017503 basophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions. http://purl.obolibrary.org/obo/CL_0017504 polychromatophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland A submucosal gland found in a respiratory tract. http://purl.obolibrary.org/obo/UBERON_0039856 right ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/UBERON_0039857 left ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some left renal vein that drains the left pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/GO_0140962 multicellular organismal-level chemical homeostasis http://purl.obolibrary.org/obo/GO_0048878 chemical homeostasis A homeostatic process involved in the maintenance of a steady state level of a chemical within extracellular body fluids, such as blood, xylem or phloem, of a multicellular organism. This is distinct from maintenance of cellular homeostasis, which occurs within a cell. http://purl.obolibrary.org/obo/GO_0062023 collagen-containing extracellular matrix http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. http://purl.obolibrary.org/obo/UBERON_0036285 wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of aorta. http://purl.obolibrary.org/obo/UBERON_0036286 wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of pulmonary trunk. http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a lip region [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The disaggregation of a cell-cell junction into its constituent components. http://purl.obolibrary.org/obo/CL_0011019 mesothelial cell of epicardium http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesothelial cell that is part of the epicardium. http://purl.obolibrary.org/obo/CL_0011021 fibroblast of upper back skin http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back A fibroblast that is part of upper back skin. http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A fibroblast that is part of skin of back. http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell Any serous secreting cell that is part of the tracheobronchial epithelium. http://purl.obolibrary.org/obo/CL_0019002 tracheobronchial chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte Any chondrocyte that is part of the tracheobronchial tree. http://purl.obolibrary.org/obo/GO_0160038 somatic sensory system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain. http://purl.obolibrary.org/obo/CL_0001066 erythroid progenitor cell, mammalian http://purl.obolibrary.org/obo/CL_0000038 erythroid progenitor cell A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). http://purl.obolibrary.org/obo/CL_0008017 adult skeletal muscle myoblast http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. http://purl.obolibrary.org/obo/CL_0008022 endocardial cushion cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. http://purl.obolibrary.org/obo/CL_0008025 noradrenergic neuron http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0011007 paraxial cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites. http://purl.obolibrary.org/obo/CL_0011012 neural crest cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a dermis. http://purl.obolibrary.org/obo/CL_2000013 fibroblast of skin of abdomen http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a skin of abdomen. http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any lung endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000287 eye photoreceptor cell Any photoreceptor cell that is part of a compound eye. http://purl.obolibrary.org/obo/CL_2000020 inner cell mass cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any native cell that is part of a inner cell mass. http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any native cell that is part of a cardiac septum. http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that is part of a central nervous system. http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that is part of a peripheral nervous system. http://purl.obolibrary.org/obo/CL_2000042 embryonic fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a embryo. http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a brain. http://purl.obolibrary.org/obo/CL_2000046 ventricular cardiac muscle cell http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell Any cardiac muscle cell that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/CL_2000047 brainstem motor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any motor neuron that is part of a brainstem. http://purl.obolibrary.org/obo/CL_2000051 splenic fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a spleen. http://purl.obolibrary.org/obo/CL_2000053 splenic endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell Any endothelial cell that is part of a spleen. http://purl.obolibrary.org/obo/CL_2000063 ovarian fibroblast http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary Any fibroblast that is part of a female gonad. http://purl.obolibrary.org/obo/CL_2000064 ovarian surface epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell Any epithelial cell that is part of a female gonad. http://purl.obolibrary.org/obo/CL_2000066 cardiac ventricle fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/CL_2000067 cardiac atrium fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac atrium. http://purl.obolibrary.org/obo/CL_2000068 pericardium fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a pericardium. http://purl.obolibrary.org/obo/CL_2000069 gallbladder fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a gallbladder. http://purl.obolibrary.org/obo/CL_2000070 optic choroid fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a optic choroid. http://purl.obolibrary.org/obo/CL_2000072 adipose microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a adipose tissue. http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Any migratory neural crest cell that is part of a cardiac neural crest. http://purl.obolibrary.org/obo/CL_2000074 splenocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte Any leukocyte that is part of a spleen. http://purl.obolibrary.org/obo/CL_2000080 mesenchymal stem cell of abdominal adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an abdomen. http://purl.obolibrary.org/obo/CL_2000093 bronchus fibroblast of lung http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung Any fibroblast of lung that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the left side of the heart. http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the right side of the heart. http://purl.obolibrary.org/obo/UBERON_0035639 ocular adnexa http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva. http://purl.obolibrary.org/obo/UBERON_0035804 future mouth http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The primordial mouth region of the developing head. http://purl.obolibrary.org/obo/UBERON_0035805 muscle layer of sigmoid colon http://purl.obolibrary.org/obo/UBERON_0012489 muscle layer of colon A muscle layer that is part of the sigmoid colon. http://purl.obolibrary.org/obo/UBERON_0035820 peritoneal sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity. http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that activates or increases the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_0106027 neuron projection organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. http://purl.obolibrary.org/obo/GO_0110021 cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/GO_0110023 negative regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/GO_0110024 positive regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Any gland that is part os the respiratory system. http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/GO_0061971 replacement bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. http://purl.obolibrary.org/obo/GO_0061972 dermal bone morphogenesis http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis The process in which bone which forms superficially in the organism are generated and organized. http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bone which forms deep in the organism are generated and organized. http://purl.obolibrary.org/obo/GO_0140513 nuclear protein-containing complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell found in the lamina propria of the large intestine. http://purl.obolibrary.org/obo/CL_0009022 stromal cell of lamina propria of small intestine http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stromal cell found in the lamina propria of the small intestine. http://purl.obolibrary.org/obo/CL_0009024 mesothelial cell of small intestine http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is part of the small intestine. http://purl.obolibrary.org/obo/CL_0009025 mesothelial cell of colon http://purl.obolibrary.org/obo/CL_0008041 mesothelial cell of intestine A mesothelial cell that is part of the colon. http://purl.obolibrary.org/obo/CL_0009100 hepatic portal fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast located in the portal triad. Hepatic portal fibroblast are a non-parenchymal cell population located adjacent to bile duct epithelia in liver and are distinct from stellate cells. They differentiate into fibrogenic myofibroblasts during chronic injury states producing high levels of collagen. http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins. http://purl.obolibrary.org/obo/GO_0120331 endothelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of an endothelial tube. http://purl.obolibrary.org/obo/CL_4023168 somatosensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli. http://purl.obolibrary.org/obo/CL_4023079 midbrain-derived inhibitory neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A GABAergic inhibitory neuron that is derived from the midbrain. http://purl.obolibrary.org/obo/CL_4033061 endothelial cell of central vein of liver http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell that is part of a central vein of liver. http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa). http://purl.obolibrary.org/obo/UBERON_0036264 zygomaticotemporal nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit. http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Directly binding to a specific protein and delivering it to a specific cellular location. http://purl.obolibrary.org/obo/GO_0120222 regulation of blastocyst development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of blastocyst development. http://purl.obolibrary.org/obo/UBERON_8000006 left side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/UBERON_8000007 right side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/UBERON_8410001 small intestine venule http://purl.obolibrary.org/obo/UBERON_0001979 venule Venule of villus of small intestine. http://purl.obolibrary.org/obo/UBERON_8410004 small intestine arteriole http://purl.obolibrary.org/obo/UBERON_0001980 arteriole Arteriole of villus of small intestine. http://purl.obolibrary.org/obo/UBERON_8410008 venule of anorectum http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_8410009 arteriole of anorectum http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole that is located in the anorectum. http://purl.obolibrary.org/obo/UBERON_8410015 arteriole of colon http://purl.obolibrary.org/obo/UBERON_0001980 arteriole An arteriole located in the colon. http://purl.obolibrary.org/obo/UBERON_8410043 bronchus submucosal gland http://purl.obolibrary.org/obo/UBERON_8410077 airway submucosal gland A submucosal gland located in a bronchus. http://purl.obolibrary.org/obo/UBERON_8410048 venule of colon http://purl.obolibrary.org/obo/UBERON_0001979 venule A venule located in the colon. http://purl.obolibrary.org/obo/UBERON_8410050 anorectum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A subdivision of the digestive tract in humans that includes the rectum, the anal canal and the anus. http://purl.obolibrary.org/obo/UBERON_8410056 capillary of anorectum http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of the anorectum. http://purl.obolibrary.org/obo/UBERON_8410057 capillary of colon http://purl.obolibrary.org/obo/UBERON_0001982 capillary A capillary that is part of the colon. http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle. http://purl.obolibrary.org/obo/CL_0009006 enteroendocrine cell of small intestine http://purl.obolibrary.org/obo/CL_1001598 small intestine secretory cell An enteroendocrine cell that is located in the small intestine. http://purl.obolibrary.org/obo/CL_0009040 stromal cell of lamina propria of colon http://purl.obolibrary.org/obo/CL_0009021 stromal cell of lamina propria of large intestine A stromal cell found in the lamina propria of the colon. http://purl.obolibrary.org/obo/CL_0009042 enteroendocrine cell of colon http://purl.obolibrary.org/obo/CL_1001516 intestinal enteroendocrine cell An enteroendocrine cell that is located in the colon. http://purl.obolibrary.org/obo/CL_0009043 intestinal crypt stem cell of colon http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the crypt of Lieberkuhn of colon. http://purl.obolibrary.org/obo/UBERON_8450002 excretory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system An anatomical system that eliminates waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/UBERON_8480029 skin of external genitalia http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin that is part of the external genitalia. http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases catecholamine as a neurotransmitter. http://purl.obolibrary.org/obo/UBERON_8600012 submucosal gland acinus http://purl.obolibrary.org/obo/UBERON_0014717 mucous acinus A spherical or tubular structure in a submucosal gland that produces and secretes mucus and other substances into the ducts leading to the surface epithelium. http://purl.obolibrary.org/obo/GO_0150098 glial cell-neuron signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum. http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from a cell, into the extracellular region. http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine http://purl.obolibrary.org/obo/CL_0002253 epithelial cell of large intestine An intestinal stem cell that is located in the large intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the large intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/CL_0009017 intestinal crypt stem cell of small intestine http://purl.obolibrary.org/obo/CL_0002254 epithelial cell of small intestine An intestinal stem cell that is located in the small intestine crypt of Liberkuhn. These stem cells reside at the bottom of crypts in the small intestine and are highly proliferative. They either differentiate into transit amplifying cells or self-renew to form new stem cells. http://purl.obolibrary.org/obo/CL_0010017 zygote http://purl.obolibrary.org/obo/CL_0000000 cell A zygote in a plant or an animal. http://purl.obolibrary.org/obo/CL_0011027 skeletal muscle fibroblast http://purl.obolibrary.org/obo/CL_1001609 muscle fibroblast Any fibroblast that is part of skeletal muscle tissue. http://purl.obolibrary.org/obo/CL_0019020 extrahepatic cholangiocyte http://purl.obolibrary.org/obo/CL_1000488 cholangiocyte An epithelial cell of the extrahepatic bile ducts, including the left and right hepatic duct, common hepatic duct, and common bile duct. They are columnar in shape, and have a large nuclear-to-cytoplasmic ratio relative to small/intrahepatic cholangiocytes. http://purl.obolibrary.org/obo/CL_0019021 endothelial cell of periportal hepatic sinusoid http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid An endothelial cell found in the periportal region hepatic sinusoid, near the portal triad. The fenestrae of these cells are larger but fewer in number compared with those of endothelial cells near the centrilobular region of the hepatic sinusoid. http://purl.obolibrary.org/obo/CL_0019022 endothelial cell of pericentral hepatic sinusoid http://purl.obolibrary.org/obo/CL_1000398 endothelial cell of hepatic sinusoid An endothelial cell found in the centrilobular region hepatic sinusoid, near the central vein. The fenestrae of these cells are smaller but more numerous compared with those of endothelial cells near the periportal region of the hepatic sinusoid. http://purl.obolibrary.org/obo/UBERON_8410024 intestinal junction http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction An anatomical junction between two parts of the intestine. http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junction between two parts of the digestive tract. http://purl.obolibrary.org/obo/CL_0009052 smooth muscle cell of anorectum http://purl.obolibrary.org/obo/CL_1000279 smooth muscle cell of large intestine A smooth muscle cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_0009061 intestinal crypt stem cell of anorectum http://purl.obolibrary.org/obo/CL_0009016 intestinal crypt stem cell of large intestine An intestinal crypt stem cell that is located in the anorectum. http://purl.obolibrary.org/obo/CL_4033005 serous secreting cell of bronchus submucosal gland http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A(n) serous secreting cell that is part of a(n) bronchus submucosal gland. http://purl.obolibrary.org/obo/CL_4033008 vein endothelial cell of respiratory system http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell A(n) vein endothelial cell that is part of a(n) respiratory system. http://purl.obolibrary.org/obo/CL_4033037 mucus secreting cell of tracheobronchial tree submucosal gland http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree A mucus secreting cell of a submucosal gland of the tracheobronchial tree. http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The cellular DNA metabolic process resulting in the breakdown of a nucleic acid. http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a lipid from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of actin filament organization. http://purl.obolibrary.org/obo/GO_0062033 positive regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0062094 stomach development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing. http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. http://purl.obolibrary.org/obo/CL_0009094 endothelial cell of hepatic portal vein http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell An endothelial cell that is part of a hepatic portal vein. http://purl.obolibrary.org/obo/UBERON_8600024 pulmonary venule http://purl.obolibrary.org/obo/UBERON_0003512 lung blood vessel A venule that is part of a lung and drains oxygenated blood from pulmonary capillaries. A pulmonary venule merges into a pulmonary vein branch that runs in the pulmonary interlobular septa. http://purl.obolibrary.org/obo/UBERON_8450003 embryonic craniocervical region http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region A craniocervical region that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_6001730 insect larval head http://purl.obolibrary.org/obo/UBERON_0000033 head Any head that is part of some larva. http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ Any sense organ that is part of some larva. http://purl.obolibrary.org/obo/UBERON_6007240 insect embryonic/larval sensillum http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ Any sensillum (UBERON:6007152) that is part of some larva (UBERON:6001727). http://purl.obolibrary.org/obo/UBERON_6007242 insect embryonic/larval head sensillum http://purl.obolibrary.org/obo/UBERON_6007280 insect embryonic/larval head sense organ Any sensillum (UBERON:6007152) that is part of some larval head (UBERON:6001730). http://purl.obolibrary.org/obo/UBERON_6007280 insect embryonic/larval head sense organ http://purl.obolibrary.org/obo/UBERON_6002639 insect larval sense organ Any sense organ (UBERON:6005155) that is part of some larval head (UBERON:6001730). http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid A bodily fluid that is located in the coelom. http://purl.obolibrary.org/obo/UBERON_0036242 post-embryonic notochord http://purl.obolibrary.org/obo/UBERON_0002328 notochord A notochord that has persisted beyond the embryonic stage. http://purl.obolibrary.org/obo/GO_0110114 negative regulation of lipid transporter activity http://purl.obolibrary.org/obo/GO_0032410 negative regulation of transporter activity Any process that decreases the frequency, rate, or extent of lipid transporter activity. http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse Any process that regulates translation occurring at the presynapse. http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0106215 negative regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0106216 positive regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/GO_0150107 positive regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/ECAO_0000050 not fully grown oocyte stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent A developing female gamete that started growing in size by accumulation of yolk proteins. At this stage, it is characterized by the presence of a large nucleus, the germinal vesicle, which contains a prominent nucleolus and occupies most of the cytoplasm. http://purl.obolibrary.org/obo/ECAO_0000060 fully grown oocyte with centered germinal vesicle stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent A developing female gamete that has reached its full size. It has grown up to ten times its original size, i.e. 80 to 100microm. It also displays a large germinal vesicle that is centered, but it is still not competent for fertilization. http://purl.obolibrary.org/obo/ECAO_0000070 fully grown oocyte with off-centered germinal vesicle stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent A developing female gamete that has reached its full size and in which the germinal vesicle has moved asymmetrically to the cell periphery. The germinal vesicle is now close to the animal pole. http://purl.obolibrary.org/obo/ECAO_0000080 fully grown oocyte with no nucleus stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent A developing female gamete in which the germinal vesicle has broken down. The germinal vesicle is no longer visible. However, the female gamete is still not mature. It is undergoing meiotic maturation, extruding successively a first and a second polar body. http://purl.obolibrary.org/obo/ECAO_0000090 mature oocyte stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent A mature female gamete that has achieved its meiotic maturation and in which the female pronucleus is visible. The mature oocyte is arrested in G1 phase and its average size is 80 to 100 µm. It is surrounded by a transparent jelly coat that is about 30 µm thick. It is competent to fertilization and it is located in the female gonad where it may be stored for weeks to months before its release in sea water by spawning. In the P. lividus species, the mature female gametes are characterized by the presence of pigment granules concentrated in a subequatorial band. This band is classically called the pigment band and allows to visualize the first embryonic axis, i.e. the animal-vegetal axis, which is perpendicular to the band. http://purl.obolibrary.org/obo/ECAO_0000100 spermatogenesis period http://purl.obolibrary.org/obo/BFO_0000003 occurrent Period during which male gametes (or spermatozoa, or spermatozoid) develop and mature from primordial male germ cells to generate cells competent to further development upon fertilization of a mature oocyte. http://purl.obolibrary.org/obo/ECAO_0000110 developing spermatozoa stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent A developing, immature male gamete undergoing mitosis and meiosis to ultimately produce mature spermatozoa. http://purl.obolibrary.org/obo/ECAO_0000120 mature spermatozoid stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent A mature male gamete that is composed of a head, encompassing a compact nucleus, a neck, a middle piece, and a tail (or flagellum) that propels it towards the oocyte upon spawning. http://purl.obolibrary.org/obo/ECAO_0000140 1-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent Fertilization has occurred, but the zygote has not undergone cell division. The embryo is a single diploid cell surrounded by a fertilization envelope http://purl.obolibrary.org/obo/ECAO_0000160 2-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of two cells and is surrounded by a fertilization envelope. The first cleavage division has taken place meridionally (i.e. along the animal-vegetal axis), thereby generating two blastomeres of equal size, each containing both animal and vegetal cytoplasm. http://purl.obolibrary.org/obo/ECAO_0000170 4-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of four cells and is surrounded by a fertilization envelope. The second cleavage division has taken place meridional and perpendicular to the first cleavage division. This has produced four blastomeres of equal size, all of which contain both animal and vegetal cytoplasm. http://purl.obolibrary.org/obo/ECAO_0000180 8-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of eight cells and is surrounded by a fertilization envelope. The third cleavage division has taken place equatorial and perpendicular to the first two cleavage divisions. http://purl.obolibrary.org/obo/ECAO_0000190 16-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 16 cells and is surrounded by a fertilization envelope. http://purl.obolibrary.org/obo/ECAO_0000200 28-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 28 cells and is surrounded by a fertilization envelope. http://purl.obolibrary.org/obo/ECAO_0000210 32-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 32 cells and is surrounded by a fertilization envelope. http://purl.obolibrary.org/obo/ECAO_0000220 56-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 56 cells and is surrounded by a fertilization envelope. http://purl.obolibrary.org/obo/ECAO_0000230 60-cell stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of 60 cells and is surrounded by a fertilization envelope. http://purl.obolibrary.org/obo/ECAO_0000240 blastula period http://purl.obolibrary.org/obo/BFO_0000003 occurrent The period that immediately follows cleavage and precedes gastrulation. It is characterized by the progressive maturation of the embryo into a hollow sphere, which is one cell layer thick and encompasses a central, fluid-filled cavity (the blastocoel). This period is associated with a gradual increase in cell cycle length and a loss of mitotic synchrony. During mitosis, cells round up and the wall of the blastula becomes irregular, while during interphase the cells flatten and the wall of the blastula appears smooth. During this period, the blastocoel gradually expands and becomes lined by a thin basal lamina. Cells in the wall of the blastula thereby become polarized; the inner (basal) surface of each cell contacts the basal lamina while the outer (apical) surface contacts the hyaline layer, an extracellular matrix that surrounds the embryo. Each cell further forms a single apical cilium. The onset of ciliary motility causes the blastula to move within the fertilization envelope and, after hatching, coordinated ciliary beating allows the embryo to swim freely. The blastula period culminates in the formation of the vegetal plate, a placode of elongated, presumptive endomesoderm cells. http://purl.obolibrary.org/obo/ECAO_0000250 very early blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of about 100 cells and is surrounded by a fertilization envelope. All cells are about the same size and there are no obvious morphological indications of embryonic polarity or territories. The embryo has started to transform into a hollow sphere. http://purl.obolibrary.org/obo/ECAO_0000260 early blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of about 100-200 cells and is surrounded by a fertilization envelope. Most blastomeres have completed at least one additional mitotic division since the 60- or 64-cell stage. All cells are approximately the same size and there are no obvious morphological indications of the primary or secondary embryonic axes. All cells have begun to acquire an apical-basal polarity and the embryo is beginning to transform into a hollow sphere with a monolayered epithelial wall and a fluid-filled cavity (the blastocoel) in the center. http://purl.obolibrary.org/obo/ECAO_0000270 mid-blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of about 200-500 cells and is surrounded by a fertilization envelope. Most cells have completed at least one additional mitotic division since the early blastula stage. The cell divisions are now less synchronous than at earlier stages. The embryo remains spherical in shape and one cell layer thick. It does not display any morphological indications of the embryonic axes or of the vegetal plate. The cells have started to flatten on their inner (basal) surface, further contributing to the enlargement of the blastocoel, which has expanded since the early blastula stage. http://purl.obolibrary.org/obo/ECAO_0000280 late blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of about 600-1000 cells. Most cells have completed at least one additional mitotic division since the mid-blastula stage and developed an apical cilium. The embryo is still spherical in shape and one cell layer thick. It still lacks obvious morphological landmarks of the embryonic axes and of the vegetal plate. Cells have further continued to flatten along the apical-basal axis, accentuating the enlargement of the blastocoel. They are also now joined to one another apically by septate and adherens junctions and laterally by desmosomes. http://purl.obolibrary.org/obo/ECAO_0000290 hatched blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The fertilization envelope has started to break down due to the secretion by ectodermal cells of the hatching enzyme, a metalloprotease that digests the fertilization envelope and frees the embryo. The embryo rotates within the envelope or swims away as soon as it is free.The vegetal plate has not formed. http://purl.obolibrary.org/obo/ECAO_0000300 swimming blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has hatched from the fertilization envelope and swims freely. It is still a hollow sphere that is one cell layer thick, but the cells constituting the vegetal plate (i.e. located at the vegetal pole) have started thickening along the apico-basal axis, thereby creating a morphological landmark that enables orienting the embryo along the animal-vegetal axis. http://purl.obolibrary.org/obo/ECAO_0000310 late swimming blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo has started elongated along the animal-vegetal axis. Its vegetal region has further continued to thicken and it is marked by a characteristic 'V' shape formed by the blastocoel at the level of the cells constituting the vegetal plate, thereby pointing to the vegetal pole. http://purl.obolibrary.org/obo/ECAO_0000320 gastrula period http://purl.obolibrary.org/obo/BFO_0000003 occurrent The period that immediately follows the blastula period and precedes organogenesis. It is characterized by extensive movements of cells in the vegetal region of the embryo. This period culminates in the formation of a multilayered embryo composed of three primary germ layers (ectoderm, mesoderm, and endoderm). The cell movements of gastrulation include ingression of migratory, mesenchymal cells into the blastocoel and invagination of the vegetal plate that creates the primitive gut (archenteron). http://purl.obolibrary.org/obo/ECAO_0000330 mesenchyme blastula episode http://purl.obolibrary.org/obo/BFO_0000003 occurrent The first episode of the gastrulation period, characterized by the ingression into the blastocoel of the skeletogenic primary mesenchyme cells (PMCs), prior to the invagination of the vegetal plate. http://purl.obolibrary.org/obo/ECAO_0000340 early mesenchyme blastula episode http://purl.obolibrary.org/obo/BFO_0000003 occurrent Skeletogenic primary mesenchyme cells (PMCs) are starting to ingress from the vegetal plate into the blastocoel through an epithelial–to-mesenchymal transition (EMT). http://purl.obolibrary.org/obo/ECAO_0000350 mid-mesenchyme blastula episode http://purl.obolibrary.org/obo/BFO_0000003 occurrent Almost all skeletogenic primary mesenchyme cells (PMCs) have ingressed into the blastocoel and remain in a mound on the vegetal plate. http://purl.obolibrary.org/obo/ECAO_0000360 late mesenchyme blastula episode http://purl.obolibrary.org/obo/BFO_0000003 occurrent All skeletogenic primary mesenchyme cells (PMCs) have ingressed into the blastocoel. Many of these cells have extended filopodia and migrated away from the vegetal plate. The cells are found along the blastocoel wall, although they remain concentrated in the vegetal hemisphere of the embryo. The vegetal plate has flattened following the ingression of the PMCs. However, it has not started to invaginate. It is now composed at its center of the 8 small micromere descendants (the germ line) surrounded by non-skeletogenic mesoderm (NSM). http://purl.obolibrary.org/obo/ECAO_0000370 invagination episode http://purl.obolibrary.org/obo/BFO_0000003 occurrent Period during which the inpocketing and elongation of the archenteron takes place. http://purl.obolibrary.org/obo/ECAO_0000380 blastopore formation stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is characterized morphologically by a slight invagination of the vegetal plate. This invagination has generated the anterior portion of the archenteron (primitive digestive tract) and the blastopore, an opening that will persist as the larval anus. http://purl.obolibrary.org/obo/ECAO_0000390 early gastrula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The archenteron (primitive digestive tract) has elongated up to 1/3 of its final length. This elongation has occurred through the inward movement of all non-skeletogenic mesoderm (NSM) cells and part of the endoderm. http://purl.obolibrary.org/obo/ECAO_0000400 mid-gastrula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The archenteron (primitive digestive tract) has elongated to about half (1/3-2/3) of its final length. http://purl.obolibrary.org/obo/ECAO_0000410 late gastrula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The archenteron (primitive digestive tract) has elongated up to more than 2/3 of its maximal length. http://purl.obolibrary.org/obo/ECAO_0000420 organogenesis period http://purl.obolibrary.org/obo/BFO_0000003 occurrent The period that immediately follows the gastrula period. It is characterized by the progressive maturation of tissues and organs. This period culminates in the opening of the mouth. http://purl.obolibrary.org/obo/ECAO_0000430 prism stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is mainly characterized morphologically by a typical triangular shape, the beginning of the tripatition of the digestive tract and the presence of pigmented cells. The oral (or ventral) ectoderm has by now even more flattened, making an almost perfect right angle with the blastoporal side of the embryo. By contrast, on the opposite side, the aboral (or dorsal) ectoderm has round up and slightly elongated, thereby forming the primitive apex of the future larvae. These changes have conferred the embryo a typical and easy recognizable triangular shape. In the oral ectoderm, a small depression has further appeared, called the stomodeum, which will later fuse with the tip of the archenteron to form the mouth. In the blastocoel, the digestive tract has also by now bended toward the stomodeum and started to become tripartite. The cardiac sphincter has started forming, separating the future esophagus from the future stomach. The triradiate spicules have also continued elongating, thereby forming by now, towards the animal pole, the right and left dorsoventral connecting rods, towards the apex, the body rods, and along the vegetal, oral ectoderm the left and right ventral transverse rods. Moreover, some non-skeletogenic mesenchyme cells (or NSM cells, secondary mesenchyme cells or SMC) have started becoming pigmented and inserted into the aboral ectoderm. These cells represent part of the future immune system of the larvae along with other blastocoelar cells that are present in the blastocoel around the gut. In the vicinity of the future esophagus, other non-skeletogenic mesoderm descendant cells along with some endoderm cells have further arranged to form a single unpaired coelomic pouch. At the animal pole, the apical pole domain has also started to flatten making the embryo look like a square when viewed from the oral side, and it still arbors a tuft a long and immotile cilia. Finally, within the apical pole domain, but not yet in the ciliary band, molecular labeling surveys also start by this stage to reveal the presence of differentiating neuronal cells. http://purl.obolibrary.org/obo/ECAO_0000450 early feeding larva period http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage Biological process during which the specific outcome is the progression of a free-living larva before the development of the adult. Indirect development represents the mainstream developmental mode of metazoans. This process usually starts with the emergence of a larva that is planktonic and stops at the end of metamorphosis once the animal assumes adult characters. http://purl.obolibrary.org/obo/ECAO_0000460 early pluteus larva stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is by now a fully formed pluteus larva. The mouth has opened and the digestive tract is becoming functional. On the ventral side, the mouth is surrounded anteriorly by an oral hood and posteriorly by two postoral arms. On the dorsal side, the apex has lengthened. The skeleton has indeed continued extending, expending the dorsoventral connecting rods, the body rods, and the ventral transverse rods as well as developing the anterolateral rods and the postoral rods. Within the larva, the tripartition of the digestive tract has further progressed. The cardiac sphincter is now fully formed in between the esophagus and the stomach, and the pyloric sphincter in between the stomach and the intestine and the anal sphincter at the level of the anus have also started forming. Around the esophagus, the coelomic pouch has further developed into two bilobed sacs (or pouches), one on each side of the digestive tract. Finally, within the apical pole domain, as well as within the ciliary band, differentiated neurons with their extended axons can also now be distinguished by immunostaining. In parallel, the apical tuft of long and immotile cilia remains discernable at the tip of the oral hood, while in parallel the ciliary band has further started growing a concentrated number of intermediate size motile cilia, which will be used by the larva to swim directionally. http://purl.obolibrary.org/obo/ECAO_0000470 4-arm pluteus larva stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The larva is characterized by the presence, on the ventral side, of four extended arms (two anterolateral arms at the level of the oral hood and two postoral arms) and on the dorsal side by a sleeked apex. The larva now possesses a completely tripartite and functional digestive tract composed of an esophagus, a stomach, and an intestine, respectively limited by a cardiac sphincter, a pyloric sphincter, and an anal sphincter. http://purl.obolibrary.org/obo/ECAO_0000480 late feeding larva period http://purl.obolibrary.org/obo/BFO_0000003 occurrent To be written http://purl.obolibrary.org/obo/ECAO_0000490 6-arm pluteus larva stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The larva is characterized by the presence on the ventral side of six arms, and by the development, on the anterior midline of the esophagus, of the dorsal arch. http://purl.obolibrary.org/obo/ECAO_0000500 8-arm pluteus larva stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The larva is characterized by the presence on the ventral side of eight arms and by the development within the larva, on the left side of the stomach, of the adult rudiment. This stage is relatively long. It includes distinct changes occurring to the larva as well as within the larva, although the larva consistently exhibits 8 arms. http://purl.obolibrary.org/obo/ECAO_0000510 competent pluteus larva stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The competent pluteus larva is characterized by the presence, within the larva, on the left side of its stomach, of the adult rudiment. The rudiment is now the size of or even bigger than the stomach and harbors five long primary podia (i.e. tube feet) and five quartets of definitive spines. Under the right environemental cue, the larva is competent to undergo metamorphosis. http://purl.obolibrary.org/obo/ECAO_0000520 metamorphic larva stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The metamorphic larva stage is essentially when the larva undergoes metamorphsis. The larva goes through drastic morphological changes to transofrm the bilateral, planctonic larva into a benthic, pentaradial juvenile. http://purl.obolibrary.org/obo/ECAO_0000540 juvenile period http://purl.obolibrary.org/obo/BFO_0000003 occurrent Period during which a young benthic individual, posing as a small adult, grows but remains unable to reproduce. http://purl.obolibrary.org/obo/ECAO_0000550 early juvenile stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The early juvenile is morphologically similar to a miniature sea urchin adult. It harbors primary podia (or tube feet) and definitive spines, along with other appendages (e.g., immature spines, pedicellariae). Compare to the adult, however, it is smaller in size, deprived of a functional digestive system, and is sexually immature. http://purl.obolibrary.org/obo/ECAO_0000560 late juvenile stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The late juvenile still looks like a small adult. Its digestive tract is now functional. However, the late juvenile remains sexually immature. http://purl.obolibrary.org/obo/ECAO_0000570 adult period http://purl.obolibrary.org/obo/BFO_0000003 occurrent Period during which the animal reaches sexual maturity. http://purl.obolibrary.org/obo/ECAO_0000580 adult stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The adult stage corresponds to a fully formed pentaradial sea urchin individual that has reached sexual maturity. The gonads have developed within the perivisceral cavity and are connected to the outside by the genital pores pierced into the genital plates. http://purl.obolibrary.org/obo/ECAO_0000590 very late blastula stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo is composed of about 800 cells and is surrounded by a fertilization envelope. The wall of the embryo is thinner and smoother than at previous stages. The vegetal plate has not formed. Many cells are ciliated but the embryo has not begun to rotate within the fertilization envelope. Note for euechinoid indirect developers: molecular labeling typically indicates the presence of 32 large micromere descendants and 4 small micromere descendants at this stage. http://purl.obolibrary.org/obo/ECAO_0000600 vegetal plate stage http://purl.obolibrary.org/obo/BFO_0000003 occurrent The embryo now displays a vegetal epithelial placode, the vegetal plate, that formed at the vegetal pole and thereby provides the first morphological indication of the animal-vegetal axis of the blastula. All cells have developed an apical cilium, although the embryo may or may not have hatched from the fertilization envelope. http://purl.obolibrary.org/obo/ECAO_0103500 echinoderm anatomy http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Material anatomical entity that has inherent 3D shape and is generated by coordinated expression of the organism's own genome http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A system that has as its parts distinct anatomical structures interconnected by anatomical structures at a lower level of granularity. Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/BFO_0000004 independent continuant A region of the whole organism without well-defined compartmental boundaries http://purl.obolibrary.org/obo/ECAO_0103550 whole organism http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Anatomical structure that is an individual member of a species and consists of one cell or more http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Anatomical structure that is an individual member of a species and consists of more than one cell http://purl.obolibrary.org/obo/ECAO_0103570 embryo http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism Anatomical entity that comprises the animal in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems http://purl.obolibrary.org/obo/ECAO_0103610 digestive system http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. http://purl.obolibrary.org/obo/ECAO_0103620 embryonic digestive system http://purl.obolibrary.org/obo/ECAO_0103610 digestive system The gastrointestinal tract that is being formed during embryonic development starting with the formation of the primitive gut tube (or archenteron) http://purl.obolibrary.org/obo/ECAO_0103630 larval digestive system http://purl.obolibrary.org/obo/ECAO_0103610 digestive system Organ system responsible for the food uptake and processing in the larva http://purl.obolibrary.org/obo/ECAO_0103650 adult digestive system http://purl.obolibrary.org/obo/ECAO_0103610 digestive system Anatomical system that processes ingested substances in the adult http://purl.obolibrary.org/obo/ECAO_0103710 reproductive system http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system Anatomical system that has as its parts the organs concerned with reproduction, i.e. the male and female gonads. http://purl.obolibrary.org/obo/ECAO_0103730 embryonic nervous system http://purl.obolibrary.org/obo/ECAO_0103720 nervous system The sum of all the structures in the embryo that will develop into the larval nervous system http://purl.obolibrary.org/obo/ECAO_0103740 larval nervous system http://purl.obolibrary.org/obo/ECAO_0103720 nervous system The sum of all the neural structures present in the larva http://purl.obolibrary.org/obo/ECAO_0103810 endoskeleton http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system Internal support structure of an animal composed of mineralized tissue. It gives shape, support and protection to the body. http://purl.obolibrary.org/obo/ECAO_0103870 water vascular system http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system The water vascular system is a hydraulic system used by sea urchins for locomotion, food and waste transportation, and respiration. The system is composed of canals connecting numerous tube feet. http://purl.obolibrary.org/obo/ECAO_0103880 hemal system http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system The hemal system contains the blood. It is composed of a complex network of vessels mainly located around the gut. http://purl.obolibrary.org/obo/ECAO_0103890 animal hemisphere http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Anatomical region that corresponds to the upper half of the embryo, which later is composed of the mesomeres, and ultimately encompasses the presumptive ectoderm http://purl.obolibrary.org/obo/ECAO_0103900 vegetal hemisphere http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Anatomical region that corresponds to the lower half of the embryo, which later is composed of the macromeres and the micromeres, and ultimately encompasses the endoderm and mesoderm http://purl.obolibrary.org/obo/ECAO_0103930 animal cortex http://purl.obolibrary.org/obo/ECAO_0103910 cell cortex Cell component comprising the outermost layer of the animal region of the oocyte. It consists of a phospholipid bilayer and associated proteins http://purl.obolibrary.org/obo/ECAO_0103940 vegetal cortex http://purl.obolibrary.org/obo/ECAO_0103910 cell cortex Cell component comprising the outermost layer of the vegetal region of the oocyte. It consists of a phospholipid bilayer and associated proteins http://purl.obolibrary.org/obo/ECAO_0103950 animal pole http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The apical region of the animal hemisphere http://purl.obolibrary.org/obo/ECAO_0103960 vegetal pole http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The apical most region of the vegetal hemisphere. Once cleavages have started the vegetal pole is characterized by the presence of the micromeres initially and then that of the small micromeres http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Anatomical structure that has as its parts a maximally connected cell compartment surrounded by a plasma membrane http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Anatomical structure that is part of a cell and that has a granularity level equal to that of a protein complex or higher. http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Any of the organs or elements that are part of the digestive system http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Any anatomical structure that is part of an embryo http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Any anatomical structure that is part of a larva http://purl.obolibrary.org/obo/ECAO_0104090 juvenile structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Any anatomical structure that is part of a juvenile http://purl.obolibrary.org/obo/ECAO_0104100 adult structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Any anatomical structure that is part of an adult http://purl.obolibrary.org/obo/ECAO_0104160 nucleus http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part A membrane-bounded organelle of in which chromosomes are housed and replicated. In most cells, it contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some specialized cell types, RNA metabolism or DNA replication may be absent http://purl.obolibrary.org/obo/ECAO_0104168 oocyte http://purl.obolibrary.org/obo/ECAO_0104580 gamete A female haploid germ cell. http://purl.obolibrary.org/obo/ECAO_0104170 germinal vesicle http://purl.obolibrary.org/obo/ECAO_0104160 nucleus The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity http://purl.obolibrary.org/obo/ECAO_0104180 equatorial pigment band http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part The subequatorial accumulation of pigment granules (the so-called ‘pigment band’) in eggs or early stage embryos, which constitutes an unambiguous marker of animal-vegetal polarity http://purl.obolibrary.org/obo/ECAO_0104190 cytoplasm http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures http://purl.obolibrary.org/obo/ECAO_0104230 fertilization envelope http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release http://purl.obolibrary.org/obo/ECAO_0104247 spermatozoid http://purl.obolibrary.org/obo/ECAO_0104580 gamete A mature male germ cell http://purl.obolibrary.org/obo/NCBITaxon_3073799 Columbimorphae http://purl.obolibrary.org/obo/NCBITaxon_3078114 Neoaves http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound http://purl.obolibrary.org/obo/CHEBI_36235 bile acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_26833 sulfur atom http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_35881 pnictogen hydride http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/NCBITaxon_124129 Acipenserinae http://purl.obolibrary.org/obo/NCBITaxon_7900 Acipenseridae http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea http://purl.obolibrary.org/obo/NCBITaxon_2301119 Rhabditomorpha http://purl.obolibrary.org/obo/UBERON_0039228 sigmoid vein http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/CHEBI_15379 dioxygen http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity http://purl.obolibrary.org/obo/ECAO_0103540 anatomical space http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/NCBITaxon_262014 Xenopus http://purl.obolibrary.org/obo/NCBITaxon_8353 Xenopus http://purl.obolibrary.org/obo/UBERON_0039261 pancreatic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0035039 rectal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0035767 intrapulmonary bronchus http://purl.obolibrary.org/obo/UBERON_0002185 bronchus http://purl.obolibrary.org/obo/NCBITaxon_110815 Xenoturbella http://purl.obolibrary.org/obo/NCBITaxon_1547233 Xenoturbellidae http://purl.obolibrary.org/obo/NCBITaxon_7899 Acipenseriformes http://purl.obolibrary.org/obo/NCBITaxon_32440 Chondrostei http://purl.obolibrary.org/obo/CHEBI_166902 noradrenaline(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative http://purl.obolibrary.org/obo/CHEBI_37826 sulfuric acid derivative http://purl.obolibrary.org/obo/CHEBI_33424 sulfur oxoacid derivative http://purl.obolibrary.org/obo/NCBITaxon_6236 Rhabditida http://purl.obolibrary.org/obo/NCBITaxon_119089 Chromadorea http://purl.obolibrary.org/obo/NCBITaxon_6340 Annelida http://purl.obolibrary.org/obo/NCBITaxon_1206795 Lophotrochozoa http://purl.obolibrary.org/obo/NCBITaxon_7878 Dipnomorpha http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_2743709 Danionidae http://purl.obolibrary.org/obo/NCBITaxon_30727 Cyprinoidei http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_8292 Amphibia http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_8504 Lepidosauria http://purl.obolibrary.org/obo/NCBITaxon_32561 Sauria http://purl.obolibrary.org/obo/NCBITaxon_6040 Porifera http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_1312402 Xenacoelomorpha http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_2697495 Spiralia http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_9254 Prototheria http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_43746 Ephydroidea http://purl.obolibrary.org/obo/NCBITaxon_43741 Acalyptratae http://purl.obolibrary.org/obo/NCBITaxon_6073 Cnidaria http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/NCBITaxon_7712 Tunicata http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_1476529 Cyclostomata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_7777 Chondrichthyes http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata http://purl.obolibrary.org/obo/NCBITaxon_8783 Palaeognathae http://purl.obolibrary.org/obo/NCBITaxon_8782 Aves http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://purl.obolibrary.org/obo/UBERON_0036553 wall of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0036925 wall of eyeball http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0037089 wall of orbit http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0036253 orifice of skull http://purl.obolibrary.org/obo/UBERON_0000161 orifice http://purl.obolibrary.org/obo/UBERON_0036351 wall of brachiocephalic artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0036352 wall of subclavian artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0036422 wall of pulmonary artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0037094 wall of common carotid artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/ECAO_0103580 larva http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism http://purl.obolibrary.org/obo/ECAO_0103590 juvenile http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism http://purl.obolibrary.org/obo/ECAO_0103600 adult http://purl.obolibrary.org/obo/ECAO_0103560 multicellular organism http://purl.obolibrary.org/obo/ECAO_0103760 adult nervous system http://purl.obolibrary.org/obo/ECAO_0103720 nervous system http://purl.obolibrary.org/obo/ECAO_0103800 adult muscular system http://purl.obolibrary.org/obo/ECAO_0103770 muscular system http://purl.obolibrary.org/obo/UBERON_0036362 wall of anal canal http://purl.obolibrary.org/obo/UBERON_0001169 wall of large intestine http://purl.obolibrary.org/obo/UBERON_2001073 axial vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0036073 respiratory primordium mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0036343 wall of gallbladder http://purl.obolibrary.org/obo/UBERON_0003697 abdominal wall http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0036072 respiratory primordium epithelium http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/NCBITaxon_186622 Acipenseroidei http://purl.obolibrary.org/obo/NCBITaxon_7899 Acipenseriformes http://purl.obolibrary.org/obo/NCBITaxon_8930 Columbidae http://purl.obolibrary.org/obo/NCBITaxon_8929 Columbiformes http://purl.obolibrary.org/obo/NCBITaxon_8798 Struthioniformes http://purl.obolibrary.org/obo/NCBITaxon_8783 Palaeognathae http://purl.obolibrary.org/obo/NCBITaxon_8800 Struthio http://purl.obolibrary.org/obo/NCBITaxon_8799 Struthionidae http://purl.obolibrary.org/obo/NCBITaxon_8801 Struthio camelus http://purl.obolibrary.org/obo/NCBITaxon_8800 Struthio http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/NCBITaxon_124130 Acipenserini http://purl.obolibrary.org/obo/NCBITaxon_124129 Acipenserinae http://purl.obolibrary.org/obo/NCBITaxon_8799 Struthionidae http://purl.obolibrary.org/obo/NCBITaxon_8798 Struthioniformes http://purl.obolibrary.org/obo/NBO_0000747 jaw movement http://purl.obolibrary.org/obo/NBO_0000007 mouth movement http://purl.obolibrary.org/obo/NCBITaxon_8929 Columbiformes http://purl.obolibrary.org/obo/NCBITaxon_3073799 Columbimorphae http://purl.obolibrary.org/obo/NCBITaxon_105391 Canalipalpata http://purl.obolibrary.org/obo/NCBITaxon_105389 Sedentaria http://purl.obolibrary.org/obo/NCBITaxon_6362 Sabellida http://purl.obolibrary.org/obo/NCBITaxon_105391 Canalipalpata http://purl.obolibrary.org/obo/NCBITaxon_7761 Myxiniformes http://purl.obolibrary.org/obo/NCBITaxon_117565 Myxini http://purl.obolibrary.org/obo/NCBITaxon_110814 Xenoturbellida http://purl.obolibrary.org/obo/NCBITaxon_1312402 Xenacoelomorpha http://purl.obolibrary.org/obo/NCBITaxon_147099 Acoelomorpha http://purl.obolibrary.org/obo/NCBITaxon_1312402 Xenacoelomorpha http://purl.obolibrary.org/obo/NCBITaxon_117565 Myxini http://purl.obolibrary.org/obo/NCBITaxon_1476529 Cyclostomata http://purl.obolibrary.org/obo/NCBITaxon_9605 Homo http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae http://purl.obolibrary.org/obo/NCBITaxon_8355 Xenopus laevis http://purl.obolibrary.org/obo/NCBITaxon_262014 Xenopus http://purl.obolibrary.org/obo/NCBITaxon_8352 Pipidae http://purl.obolibrary.org/obo/NCBITaxon_30319 Pipoidea http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea http://purl.obolibrary.org/obo/NCBITaxon_32346 melanogaster group http://purl.obolibrary.org/obo/NCBITaxon_32341 Sophophora http://purl.obolibrary.org/obo/NCBITaxon_32351 melanogaster subgroup http://purl.obolibrary.org/obo/NCBITaxon_32346 melanogaster group http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_376913 Haplorrhini http://purl.obolibrary.org/obo/NCBITaxon_8342 Anura http://purl.obolibrary.org/obo/NCBITaxon_41666 Batrachia http://purl.obolibrary.org/obo/NCBITaxon_7214 Drosophilidae http://purl.obolibrary.org/obo/NCBITaxon_43746 Ephydroidea http://purl.obolibrary.org/obo/NCBITaxon_46877 Drosophilini http://purl.obolibrary.org/obo/NCBITaxon_43845 Drosophilinae http://purl.obolibrary.org/obo/NCBITaxon_7215 Drosophila http://purl.obolibrary.org/obo/NCBITaxon_46877 Drosophilini http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_55879 Rhabditoidea http://purl.obolibrary.org/obo/NCBITaxon_6237 Caenorhabditis http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_55885 Peloderinae http://purl.obolibrary.org/obo/NCBITaxon_6243 Rhabditidae http://purl.obolibrary.org/obo/NCBITaxon_6341 Polychaeta http://purl.obolibrary.org/obo/NCBITaxon_6340 Annelida http://purl.obolibrary.org/obo/NCBITaxon_105389 Sedentaria http://purl.obolibrary.org/obo/NCBITaxon_6341 Polychaeta http://purl.obolibrary.org/obo/NCBITaxon_41324 Siboglinidae http://purl.obolibrary.org/obo/NCBITaxon_6362 Sabellida http://purl.obolibrary.org/obo/NCBITaxon_43845 Drosophilinae http://purl.obolibrary.org/obo/NCBITaxon_7214 Drosophilidae http://purl.obolibrary.org/obo/NCBITaxon_32341 Sophophora http://purl.obolibrary.org/obo/NCBITaxon_7215 Drosophila http://purl.obolibrary.org/obo/NCBITaxon_7762 Myxinidae http://purl.obolibrary.org/obo/NCBITaxon_7761 Myxiniformes http://purl.obolibrary.org/obo/NCBITaxon_7863 Holocephali http://purl.obolibrary.org/obo/NCBITaxon_7777 Chondrichthyes http://purl.obolibrary.org/obo/NCBITaxon_7864 Chimaeriformes http://purl.obolibrary.org/obo/NCBITaxon_7863 Holocephali http://purl.obolibrary.org/obo/NCBITaxon_41666 Batrachia http://purl.obolibrary.org/obo/NCBITaxon_8292 Amphibia http://purl.obolibrary.org/obo/NCBITaxon_30319 Pipoidea http://purl.obolibrary.org/obo/NCBITaxon_8342 Anura http://purl.obolibrary.org/obo/NCBITaxon_8360 Xenopodinae http://purl.obolibrary.org/obo/NCBITaxon_8352 Pipidae http://purl.obolibrary.org/obo/NCBITaxon_8505 Sphenodontia http://purl.obolibrary.org/obo/NCBITaxon_8504 Lepidosauria http://purl.obolibrary.org/obo/NCBITaxon_8506 Sphenodontidae http://purl.obolibrary.org/obo/NCBITaxon_8505 Sphenodontia http://purl.obolibrary.org/obo/NCBITaxon_8507 Sphenodon http://purl.obolibrary.org/obo/NCBITaxon_8506 Sphenodontidae http://purl.obolibrary.org/obo/NCBITaxon_9255 Monotremata http://purl.obolibrary.org/obo/NCBITaxon_9254 Prototheria http://purl.obolibrary.org/obo/NCBITaxon_9259 Tachyglossidae http://purl.obolibrary.org/obo/NCBITaxon_9255 Monotremata http://purl.obolibrary.org/obo/NCBITaxon_376913 Haplorrhini http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/NCBITaxon_2743711 Danioninae http://purl.obolibrary.org/obo/NCBITaxon_2743709 Danionidae http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0104120 rudiment http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0104130 rudiment structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0104140 non-rudiment adult structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0104270 acellular membrane http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0103660 immune system http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system http://purl.obolibrary.org/obo/ECAO_0103720 nervous system http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system http://purl.obolibrary.org/obo/ECAO_0103770 muscular system http://purl.obolibrary.org/obo/ECAO_0103520 anatomical system http://purl.obolibrary.org/obo/ECAO_0103970 animal pole domain http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0103980 blastopore http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0104020 vegetal plate http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0103640 juvenile digestive system http://purl.obolibrary.org/obo/ECAO_0103610 digestive system http://purl.obolibrary.org/obo/ECAO_0103670 embryonic immune system http://purl.obolibrary.org/obo/ECAO_0103660 immune system http://purl.obolibrary.org/obo/ECAO_0103680 larval immune system http://purl.obolibrary.org/obo/ECAO_0103660 immune system http://purl.obolibrary.org/obo/ECAO_0103690 juvenile immune system http://purl.obolibrary.org/obo/ECAO_0103660 immune system http://purl.obolibrary.org/obo/ECAO_0103700 adult immune system http://purl.obolibrary.org/obo/ECAO_0103660 immune system http://purl.obolibrary.org/obo/ECAO_0103750 juvenile nervous system http://purl.obolibrary.org/obo/ECAO_0103720 nervous system http://purl.obolibrary.org/obo/ECAO_0103780 larval muscular system http://purl.obolibrary.org/obo/ECAO_0103770 muscular system http://purl.obolibrary.org/obo/ECAO_0103790 juvenile muscular system http://purl.obolibrary.org/obo/ECAO_0103770 muscular system http://purl.obolibrary.org/obo/ECAO_0103820 embryonic endoskeleton http://purl.obolibrary.org/obo/ECAO_0103810 endoskeleton http://purl.obolibrary.org/obo/ECAO_0103830 larval endoskeleton http://purl.obolibrary.org/obo/ECAO_0103810 endoskeleton http://purl.obolibrary.org/obo/ECAO_0103840 rudiment endoskeleton http://purl.obolibrary.org/obo/ECAO_0103810 endoskeleton http://purl.obolibrary.org/obo/ECAO_0103850 juvenile endoskeleton http://purl.obolibrary.org/obo/ECAO_0103810 endoskeleton http://purl.obolibrary.org/obo/ECAO_0103860 adult endoskeleton http://purl.obolibrary.org/obo/ECAO_0103810 endoskeleton http://purl.obolibrary.org/obo/ECAO_0104000 bottle cell http://purl.obolibrary.org/obo/ECAO_0104010 embryonic cell http://purl.obolibrary.org/obo/ECAO_0104010 embryonic cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0103910 cell cortex http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0104310 microvillus http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0103990 blastopore lip http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0103920 cleavage furrow http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104148 cytoskeleton http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104150 microtubule http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104200 centrosome http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104210 mitotic spindle http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104220 meiotic spindle http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104248 aster http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104250 sperm aster http://purl.obolibrary.org/obo/ECAO_0104248 aster http://purl.obolibrary.org/obo/ECAO_0104280 vitelline membrane http://purl.obolibrary.org/obo/ECAO_0104270 acellular membrane http://purl.obolibrary.org/obo/ECAO_0104300 hyaline layer http://purl.obolibrary.org/obo/ECAO_0104270 acellular membrane http://purl.obolibrary.org/obo/ECAO_0104500 polar body http://purl.obolibrary.org/obo/ECAO_0104030 cell A small cell formed by the meiotic division of an oocyte http://purl.obolibrary.org/obo/ECAO_0104520 spermatozoid head http://purl.obolibrary.org/obo/ECAO_0104510 spermatozoid part The part of the late spermatid or spermatozoon that contains the nucleus and acrosome. http://purl.obolibrary.org/obo/ECAO_0104530 spermatozoid flagellum http://purl.obolibrary.org/obo/ECAO_0104510 spermatozoid part A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid http://purl.obolibrary.org/obo/ECAO_0104540 acrosomal vesicle http://purl.obolibrary.org/obo/ECAO_0104330 secretory vesicle An organelle that develops over the anterior half of the head in the spermatozoa http://purl.obolibrary.org/obo/ECAO_0104610 mature oocyte http://purl.obolibrary.org/obo/ECAO_0104168 oocyte A mature female gamet that has entered meiosis. http://purl.obolibrary.org/obo/ECAO_0104630 blastomere http://purl.obolibrary.org/obo/ECAO_0104010 embryonic cell An undifferentiated cell produced by early cleavages of the fertilized egg (zygote) http://purl.obolibrary.org/obo/ECAO_0104660 mesomere http://purl.obolibrary.org/obo/ECAO_0104630 blastomere Intermediate size blastomere forming the animal hemisphere of the cleaving embryo http://purl.obolibrary.org/obo/ECAO_0104670 macromere http://purl.obolibrary.org/obo/ECAO_0104630 blastomere Larger blastomere of the vegetal hemisphere of the cleaving embryo located below the equator http://purl.obolibrary.org/obo/ECAO_0104690 micromere http://purl.obolibrary.org/obo/ECAO_0104630 blastomere Small blastomere of the vegetal hemisphere of the cleaving embryo located at to the vegetal pole http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104030 cell A progenitor cell of the nervous system that will develop into a neuron http://purl.obolibrary.org/obo/ECAO_0104908 ectoderm http://purl.obolibrary.org/obo/ECAO_0105150 germ layer Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. http://purl.obolibrary.org/obo/ECAO_0105050 animal quartet http://purl.obolibrary.org/obo/ECAO_0104678 cell tier Group of four cells of equal size forming the animal hemisphere of an eight-cell stage embryo http://purl.obolibrary.org/obo/ECAO_0105060 vegetal quartet http://purl.obolibrary.org/obo/ECAO_0104678 cell tier Group of four cells of equal size forming the vegetal hemisphere of an eight-cell stage embryo http://purl.obolibrary.org/obo/ECAO_0105690 larval spicule http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element A triradiate or hexaradiate minute calcareous skeletal element that initiates most if not all skeletal structures found within the sea urchin embryo, larva and adult. http://purl.obolibrary.org/obo/ECAO_0105698 embryonic skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104110 tissue The embryonic tissue made up of loosely connected mesoderm cells that will produce all of the skeletal elements. http://purl.obolibrary.org/obo/ECAO_0106220 embryonic skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue The subset of the embryonic mesoderm that will later give rise to the skeletogenic mesenchyme and embryonic skeleton. http://purl.obolibrary.org/obo/ECAO_0106260 embryonic skeletogenic mesenchyme syncytium http://purl.obolibrary.org/obo/ECAO_0106250 syncytium Anatomical structure composed of skeletogenic mesenchyme cells that have fused to form a single syncytial network. http://purl.obolibrary.org/obo/ECAO_0106280 ventral skeletogenic mesenchyme chain http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure Subpopulation of skeletogenic mesenchyme forming a chain on the oral (i.e. ventral) side of the embryo. http://purl.obolibrary.org/obo/ECAO_0106290 dorsal skeletogenic mesenchyme chain http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure Subpopulation of skeletogenic mesenchyme forming a chain on the aboral (i.e. dorsal) side of the embryo. http://purl.obolibrary.org/obo/ECAO_0106300 right ventrolateral skeletogenic mesenchyme cluster http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure Subpopulation of skeletogenic mesenchyme forming a cluster (i.e. a group of cells) in the ventrolateral region of the embryo. http://purl.obolibrary.org/obo/ECAO_0106320 lateral chain of skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure Subpopulation of skeletogenic mesenchyme forming a chain on either side of the developing digestive tract, along the blastocoel wall and towards the animal pole. http://purl.obolibrary.org/obo/ECAO_0106330 right lateral chain of skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure Subpopulation of skeletogenic mesenchyme forming a chain along the blastocoel wall towards the animal pole on the right side of the embryo. http://purl.obolibrary.org/obo/ECAO_0106340 left lateral chain of skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure Subpopulation of skeletogenic mesenchyme forming a chain along the blastocoel wall towards the animal pole on the left side of the embryo. http://purl.obolibrary.org/obo/ECAO_0106440 pigment cell http://purl.obolibrary.org/obo/ECAO_0104030 cell a cell that contains red coloring matter http://purl.obolibrary.org/obo/ECAO_0106750 larval skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104110 tissue The mesenchyme cells that produce new skeletal elements (i.e., the posterodorsal rods, dorsal arch, and preoral rods) in the larva after feeding begins http://purl.obolibrary.org/obo/ECAO_0106858 left lateral field http://purl.obolibrary.org/obo/ECAO_0107100 lateral field The left lateral field is the lateral field located on the left side of the larva http://purl.obolibrary.org/obo/ECAO_0106860 vestibular pore http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure Opening located in the left lateral field http://purl.obolibrary.org/obo/ECAO_0107100 lateral field http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region The lateral field is located in the aboral ectoderm of the larva. It separates the anterior and posterior pairs of epaulettes http://purl.obolibrary.org/obo/ECAO_0107120 right lateral field http://purl.obolibrary.org/obo/ECAO_0107100 lateral field The right lateral field is the lateral field located on the right side of the larva http://purl.obolibrary.org/obo/ECAO_0107150 adult skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104110 tissue The mesenchyme cells that produce biomineralized elements (e.g., spines, test plates, and teeth) in the juvenile and adult. http://purl.obolibrary.org/obo/CL_0011030 dermal microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell Any microvascular endothelial cell that is part of the dermis. http://purl.obolibrary.org/obo/ECAO_0104548 small micromere descendant cell http://purl.obolibrary.org/obo/ECAO_0104630 blastomere http://purl.obolibrary.org/obo/ECAO_0104550 presumptive primordial germ cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0104570 germ cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0104700 large micromere http://purl.obolibrary.org/obo/ECAO_0104630 blastomere http://purl.obolibrary.org/obo/ECAO_0104710 large micromere descendant cell http://purl.obolibrary.org/obo/ECAO_0104630 blastomere http://purl.obolibrary.org/obo/ECAO_0104720 small micromere http://purl.obolibrary.org/obo/ECAO_0104630 blastomere http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0104910 presumptive ciliary band cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0104940 apical ganglion http://purl.obolibrary.org/obo/ECAO_0104930 ganglion http://purl.obolibrary.org/obo/ECAO_0105070 animal tier 1 http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105080 animal tier 2 http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105090 vegetal tier 1 http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105100 vegetal tier 2 http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105110 vegetal tier 1 upper http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105120 vegetal tier 1 lower http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105130 vegetal tier 2 upper http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105140 vegetal tier 2 lower http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0105160 presumptive ectoderm http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue http://purl.obolibrary.org/obo/ECAO_0105180 animal ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105190 vegetal ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105220 ectoendoderm http://purl.obolibrary.org/obo/ECAO_0105150 germ layer http://purl.obolibrary.org/obo/ECAO_0105230 endomesoderm http://purl.obolibrary.org/obo/ECAO_0105150 germ layer http://purl.obolibrary.org/obo/ECAO_0105240 inner animal pole domain http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105250 outer animal pole domain http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105270 border ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105360 dorsal arm tip ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105370 ventral arm tip ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105380 apical tuft http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105450 stomodeum http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105650 triradiate spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105628 spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105680 hexaradiate spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105628 spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0105798 dorsal arch http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0105870 scheitel http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0105890 left body rod http://purl.obolibrary.org/obo/ECAO_0105880 body rod http://purl.obolibrary.org/obo/ECAO_0105900 right body rod http://purl.obolibrary.org/obo/ECAO_0105880 body rod http://purl.obolibrary.org/obo/ECAO_0105980 larval mouth http://purl.obolibrary.org/obo/ECAO_0105970 mouth http://purl.obolibrary.org/obo/ECAO_0106000 larval anus http://purl.obolibrary.org/obo/ECAO_0105990 anus http://purl.obolibrary.org/obo/ECAO_0106020 endoderm http://purl.obolibrary.org/obo/ECAO_0105150 germ layer http://purl.obolibrary.org/obo/ECAO_0106030 archenteron http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0106040 hindgut http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0106050 dorsal hindgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106060 ventral hindgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106070 midgut http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0106080 ventral midgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106090 dorsal midgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106100 anterior midgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106110 posterior midgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106120 anterior hindgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106130 posterior hindgut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106140 foregut http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0106150 ventral foregut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106160 dorsal foregut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106170 anterior foregut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106180 posterior foregut http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106190 tip of archenteron http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106200 presumptive mesoderm http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue http://purl.obolibrary.org/obo/ECAO_0106210 mesoderm http://purl.obolibrary.org/obo/ECAO_0105150 germ layer http://purl.obolibrary.org/obo/ECAO_0106240 embryonic skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106270 subequatorial skeletogenic mesenchyme ring http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0106350 embryonic non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue http://purl.obolibrary.org/obo/ECAO_0106360 ventral non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue http://purl.obolibrary.org/obo/ECAO_0106370 dorsal non-skeletogenic mesoderm http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue http://purl.obolibrary.org/obo/ECAO_0106380 embryonic non-skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0106390 embryonic non-skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106420 presumptive blastocoelar cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106490 blastocoelar cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106620 pyloric sphincter http://purl.obolibrary.org/obo/ECAO_0106610 sphincter http://purl.obolibrary.org/obo/ECAO_0106630 cardiac sphincter http://purl.obolibrary.org/obo/ECAO_0106610 sphincter http://purl.obolibrary.org/obo/ECAO_0106640 anal sphincter http://purl.obolibrary.org/obo/ECAO_0106610 sphincter http://purl.obolibrary.org/obo/ECAO_0106650 sphincter muscle http://purl.obolibrary.org/obo/ECAO_0106550 muscle http://purl.obolibrary.org/obo/ECAO_0106660 sphincter muscle cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106700 larval esophagus http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0106708 circumesophageal muscle http://purl.obolibrary.org/obo/ECAO_0106560 larval muscle http://purl.obolibrary.org/obo/ECAO_0106710 circumesophageal muscle cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106730 larval stomach http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0106740 larval intestine http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0106810 right coelomic constriction http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0106820 left coelomic constriction http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0106830 vestibule http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0106960 stone canal http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0106970 ring canal http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0106980 radial canal http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0106990 primary pore canal http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0107040 axial sinus http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107070 ciliated epaulette http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0107390 ampulla http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107440 madreporite http://purl.obolibrary.org/obo/ECAO_0107190 genital plate http://purl.obolibrary.org/obo/ECAO_0107510 adult digestive tract http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0104878 neural structure http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0105460 ciliary band http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0105970 mouth http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0105990 anus http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0106958 axial complex http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107000 hydropore http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107050 axial organ http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107060 dorsal sac http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107170 ambulacra http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107180 interambulacra http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107200 appendage http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107418 Aristotles lantern http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107420 tooth http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107450 gonopore http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107490 juvenile digestive tract http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0107520 mesentery http://purl.obolibrary.org/obo/ECAO_0103510 anatomical structure http://purl.obolibrary.org/obo/ECAO_0105200 ventral ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105210 dorsal ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105260 central ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105280 near-apical ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105290 apical ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105300 veg1-lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105310 veg-1 oral ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105320 lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0105350 arm tip ectoderm http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0107530 perivisceral cavity http://purl.obolibrary.org/obo/ECAO_0103530 anatomical region http://purl.obolibrary.org/obo/ECAO_0106600 blastocoel http://purl.obolibrary.org/obo/ECAO_0103540 anatomical space http://purl.obolibrary.org/obo/ECAO_0104560 primordial germ cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106250 syncytium http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106410 larval non-skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106430 presumptive pigment cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106540 muscle precursor cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0106760 larval skeletogenic mesenchyme cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0107540 photosensory cell http://purl.obolibrary.org/obo/ECAO_0104030 cell http://purl.obolibrary.org/obo/ECAO_0104340 cilium http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0104350 filopodium http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0104480 spermatozoid entry point http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0104490 plasma membrane http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0104510 spermatozoid part http://purl.obolibrary.org/obo/ECAO_0104040 cell part http://purl.obolibrary.org/obo/ECAO_0106610 sphincter http://purl.obolibrary.org/obo/ECAO_0104050 digestive system element http://purl.obolibrary.org/obo/ECAO_0105628 spicule rudiment http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0105868 posterior tip of body rod http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0105880 body rod http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0107140 ambulacral plate http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0107160 interambulacral plate http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0107190 genital plate http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0107220 ocular plate http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0107230 buccal plate http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0107310 disk of primary podia http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0107330 disk of secondary podia http://purl.obolibrary.org/obo/ECAO_0104060 skeletal element http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105150 germ layer http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105440 presumptive stomodeum http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105490 animal pole ciliary band http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105500 vegetal ciliary band http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105510 lateral ciliary band http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0106310 left ventrolateral skeletogenic mesenchyme cluster http://purl.obolibrary.org/obo/ECAO_0104070 embryonic structure http://purl.obolibrary.org/obo/ECAO_0105470 oral hood ciliary band http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0105480 arm ciliary band http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0105520 oral hood http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0105530 apex http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0107080 anterior ciliated epaulette http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0107090 posterior ciliated epaulette http://purl.obolibrary.org/obo/ECAO_0104080 larval structure http://purl.obolibrary.org/obo/ECAO_0107460 gonad http://purl.obolibrary.org/obo/ECAO_0104100 adult structure http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0105400 larval tissue http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0105410 rudiment tissue http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0105420 juvenile tissue http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0105430 adult tissue http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0106400 larval non-skeletogenic mesenchyme http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0106550 muscle http://purl.obolibrary.org/obo/ECAO_0104110 tissue http://purl.obolibrary.org/obo/ECAO_0104330 secretory vesicle http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104410 mitochondrion http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104430 actin filament http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104440 nuclear part http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104470 endoplasmic reticulum http://purl.obolibrary.org/obo/ECAO_0104147 intracellular part http://purl.obolibrary.org/obo/ECAO_0104420 actin cytoskeleton http://purl.obolibrary.org/obo/ECAO_0104148 cytoskeleton http://purl.obolibrary.org/obo/ECAO_0104600 immature occyte http://purl.obolibrary.org/obo/ECAO_0104168 oocyte http://purl.obolibrary.org/obo/ECAO_0104320 apical lamina http://purl.obolibrary.org/obo/ECAO_0104270 acellular membrane http://purl.obolibrary.org/obo/ECAO_0104360 basal lamina http://purl.obolibrary.org/obo/ECAO_0104270 acellular membrane http://purl.obolibrary.org/obo/ECAO_0104370 basal laminar vesicle http://purl.obolibrary.org/obo/ECAO_0104330 secretory vesicle http://purl.obolibrary.org/obo/ECAO_0104380 apical vesicle http://purl.obolibrary.org/obo/ECAO_0104330 secretory vesicle http://purl.obolibrary.org/obo/ECAO_0104390 cortical granule http://purl.obolibrary.org/obo/ECAO_0104330 secretory vesicle http://purl.obolibrary.org/obo/ECAO_0104400 echinonectin vesicle http://purl.obolibrary.org/obo/ECAO_0104330 secretory vesicle http://purl.obolibrary.org/obo/ECAO_0104450 nucleoplasm http://purl.obolibrary.org/obo/ECAO_0104440 nuclear part http://purl.obolibrary.org/obo/ECAO_0104460 nuclear envelope http://purl.obolibrary.org/obo/ECAO_0104440 nuclear part http://purl.obolibrary.org/obo/ECAO_0104580 gamete http://purl.obolibrary.org/obo/ECAO_0104570 germ cell http://purl.obolibrary.org/obo/ECAO_0104640 blastomere of 2-cell embryo http://purl.obolibrary.org/obo/ECAO_0104630 blastomere http://purl.obolibrary.org/obo/ECAO_0104650 blastomere of 4-cell embryo http://purl.obolibrary.org/obo/ECAO_0104630 blastomere http://purl.obolibrary.org/obo/ECAO_0104680 macromere daughter cell tier http://purl.obolibrary.org/obo/ECAO_0104678 cell tier http://purl.obolibrary.org/obo/ECAO_0104750 animal pole domain presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104760 ectoderm presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104770 ciliary band presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104780 endoderm associated presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104740 presumptive neuron http://purl.obolibrary.org/obo/ECAO_0104800 larval neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104810 serotonergic neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104820 synaptotagmin-B neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104830 dopaminergic neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104840 GABAergic neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104850 sensory neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104860 biopolar neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104870 multipolar neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104950 adult neuron http://purl.obolibrary.org/obo/ECAO_0104790 neuron http://purl.obolibrary.org/obo/ECAO_0104900 ciliary band neuron http://purl.obolibrary.org/obo/ECAO_0104800 larval neuron http://purl.obolibrary.org/obo/ECAO_0104920 endoderm associated neuron http://purl.obolibrary.org/obo/ECAO_0104800 larval neuron http://purl.obolibrary.org/obo/ECAO_0104880 axon tract http://purl.obolibrary.org/obo/ECAO_0104878 neural structure http://purl.obolibrary.org/obo/ECAO_0104930 ganglion http://purl.obolibrary.org/obo/ECAO_0104878 neural structure http://purl.obolibrary.org/obo/ECAO_0104960 circumoral nerve ring http://purl.obolibrary.org/obo/ECAO_0104878 neural structure http://purl.obolibrary.org/obo/ECAO_0104970 enteric nerve plexus http://purl.obolibrary.org/obo/ECAO_0104878 neural structure http://purl.obolibrary.org/obo/ECAO_0104980 radial nerve cord http://purl.obolibrary.org/obo/ECAO_0104878 neural structure http://purl.obolibrary.org/obo/ECAO_0105030 basiepidermal nerve plexus http://purl.obolibrary.org/obo/ECAO_0104878 neural structure http://purl.obolibrary.org/obo/ECAO_0104990 primary podia associated neuron http://purl.obolibrary.org/obo/ECAO_0104950 adult neuron http://purl.obolibrary.org/obo/ECAO_0105000 secondary podia associated neuron http://purl.obolibrary.org/obo/ECAO_0104950 adult neuron http://purl.obolibrary.org/obo/ECAO_0105010 definitive spine associated neuron http://purl.obolibrary.org/obo/ECAO_0104950 adult neuron http://purl.obolibrary.org/obo/ECAO_0105020 pedicellaria associated neuron http://purl.obolibrary.org/obo/ECAO_0104950 adult neuron http://purl.obolibrary.org/obo/ECAO_0107340 buccal podia http://purl.obolibrary.org/obo/ECAO_0104990 primary podia associated neuron http://purl.obolibrary.org/obo/ECAO_0106010 presumptive endoderm http://purl.obolibrary.org/obo/ECAO_0105158 embryonic tissue http://purl.obolibrary.org/obo/ECAO_0105330 right lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0105320 lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0105340 left lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0105320 lateral ectoderm http://purl.obolibrary.org/obo/ECAO_0106560 larval muscle http://purl.obolibrary.org/obo/ECAO_0105400 larval tissue http://purl.obolibrary.org/obo/ECAO_0106828 larval epithelium http://purl.obolibrary.org/obo/ECAO_0105400 larval tissue http://purl.obolibrary.org/obo/ECAO_0106840 oral epithelium http://purl.obolibrary.org/obo/ECAO_0105400 larval tissue http://purl.obolibrary.org/obo/ECAO_0106850 aboral epithelium http://purl.obolibrary.org/obo/ECAO_0105400 larval tissue http://purl.obolibrary.org/obo/ECAO_0106570 rudiment muscle http://purl.obolibrary.org/obo/ECAO_0105410 rudiment tissue http://purl.obolibrary.org/obo/ECAO_0106580 juvenile muscle http://purl.obolibrary.org/obo/ECAO_0105420 juvenile tissue http://purl.obolibrary.org/obo/ECAO_0106590 adult muscle http://purl.obolibrary.org/obo/ECAO_0105430 adult tissue http://purl.obolibrary.org/obo/ECAO_0105550 right anterolateral arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105560 left anterolateral arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105570 right postoral arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105580 left postoral arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105590 right posterodorsal arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105600 left posterodorsal arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105610 right preoral arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105620 left preoral arm http://purl.obolibrary.org/obo/ECAO_0105540 larval arm http://purl.obolibrary.org/obo/ECAO_0105630 spicule granule http://purl.obolibrary.org/obo/ECAO_0105628 spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105660 right ventrolateral triradiate spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105650 triradiate spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105670 left ventrolateral triradiate spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105650 triradiate spicule rudiment http://purl.obolibrary.org/obo/ECAO_0105710 anonymous rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105738 right dorsoventral connecting rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105740 right anterolateral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105748 left dorsoventral connecting rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105750 left anterolateral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105760 right postoral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105770 left postoral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105780 right posterodorsal rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105790 left posterodorsal rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105800 right preoral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105810 left preoral rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105850 right ventral transverse rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105860 left ventral transverse rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105940 right recurrent rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105950 left recurrent rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105960 posterior transverse rod http://purl.obolibrary.org/obo/ECAO_0105700 skeletal rod http://purl.obolibrary.org/obo/ECAO_0105720 right anonymous rod http://purl.obolibrary.org/obo/ECAO_0105710 anonymous rod http://purl.obolibrary.org/obo/ECAO_0105730 left anonymous rod http://purl.obolibrary.org/obo/ECAO_0105710 anonymous rod http://purl.obolibrary.org/obo/ECAO_0105920 posterior tip of left body rod http://purl.obolibrary.org/obo/ECAO_0105868 posterior tip of body rod http://purl.obolibrary.org/obo/ECAO_0105930 posteror tip of right body rod http://purl.obolibrary.org/obo/ECAO_0105868 posterior tip of body rod http://purl.obolibrary.org/obo/ECAO_0107400 adult mouth http://purl.obolibrary.org/obo/ECAO_0105970 mouth http://purl.obolibrary.org/obo/ECAO_0107410 adult anus http://purl.obolibrary.org/obo/ECAO_0105990 anus http://purl.obolibrary.org/obo/ECAO_0106450 embryonic pigment cell http://purl.obolibrary.org/obo/ECAO_0106440 pigment cell http://purl.obolibrary.org/obo/ECAO_0106460 larval pigment cell http://purl.obolibrary.org/obo/ECAO_0106440 pigment cell http://purl.obolibrary.org/obo/ECAO_0106470 juvenile pigment cell http://purl.obolibrary.org/obo/ECAO_0106440 pigment cell http://purl.obolibrary.org/obo/ECAO_0106480 rudiment pigment cell http://purl.obolibrary.org/obo/ECAO_0106440 pigment cell http://purl.obolibrary.org/obo/ECAO_0106500 globular cell http://purl.obolibrary.org/obo/ECAO_0106490 blastocoelar cell http://purl.obolibrary.org/obo/ECAO_0106510 filopodial cell http://purl.obolibrary.org/obo/ECAO_0106490 blastocoelar cell http://purl.obolibrary.org/obo/ECAO_0106520 ovoid cell http://purl.obolibrary.org/obo/ECAO_0106490 blastocoelar cell http://purl.obolibrary.org/obo/ECAO_0106530 amoeboid cell http://purl.obolibrary.org/obo/ECAO_0106490 blastocoelar cell http://purl.obolibrary.org/obo/ECAO_0106670 pyloric sphincteric muscle http://purl.obolibrary.org/obo/ECAO_0106650 sphincter muscle http://purl.obolibrary.org/obo/ECAO_0106680 cardiac sphincteric muscle http://purl.obolibrary.org/obo/ECAO_0106650 sphincter muscle http://purl.obolibrary.org/obo/ECAO_0106690 anal sphincteric muscle http://purl.obolibrary.org/obo/ECAO_0106650 sphincter muscle http://purl.obolibrary.org/obo/ECAO_0106780 unpaired coelomic pouch http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106790 right coelomic pouch http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106800 left coelomic pouch http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106868 axocoel http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106880 axial coelom http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106890 hydrocoel http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106910 somatocoel http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106940 right axohydrocoel http://purl.obolibrary.org/obo/ECAO_0106770 coelom http://purl.obolibrary.org/obo/ECAO_0106870 left axocoel http://purl.obolibrary.org/obo/ECAO_0106868 axocoel http://purl.obolibrary.org/obo/ECAO_0107010 right axocoel http://purl.obolibrary.org/obo/ECAO_0106868 axocoel http://purl.obolibrary.org/obo/ECAO_0106920 left hydrocoel http://purl.obolibrary.org/obo/ECAO_0106890 hydrocoel http://purl.obolibrary.org/obo/ECAO_0107020 right hydrocoel http://purl.obolibrary.org/obo/ECAO_0106890 hydrocoel http://purl.obolibrary.org/obo/ECAO_0106930 left somatocoel http://purl.obolibrary.org/obo/ECAO_0106910 somatocoel http://purl.obolibrary.org/obo/ECAO_0106950 right somatocoel http://purl.obolibrary.org/obo/ECAO_0106910 somatocoel http://purl.obolibrary.org/obo/ECAO_0107240 genital plate AB http://purl.obolibrary.org/obo/ECAO_0107190 genital plate http://purl.obolibrary.org/obo/ECAO_0107250 genital plate BC http://purl.obolibrary.org/obo/ECAO_0107190 genital plate http://purl.obolibrary.org/obo/ECAO_0107260 genital plate CD http://purl.obolibrary.org/obo/ECAO_0107190 genital plate http://purl.obolibrary.org/obo/ECAO_0107270 genital plate DE http://purl.obolibrary.org/obo/ECAO_0107190 genital plate http://purl.obolibrary.org/obo/ECAO_0107280 genital plate EA http://purl.obolibrary.org/obo/ECAO_0107190 genital plate http://purl.obolibrary.org/obo/ECAO_0107210 pedicellaria http://purl.obolibrary.org/obo/ECAO_0107200 appendage http://purl.obolibrary.org/obo/ECAO_0107290 podia http://purl.obolibrary.org/obo/ECAO_0107200 appendage http://purl.obolibrary.org/obo/ECAO_0107350 spine http://purl.obolibrary.org/obo/ECAO_0107200 appendage http://purl.obolibrary.org/obo/ECAO_0107380 sphaeridium http://purl.obolibrary.org/obo/ECAO_0107200 appendage http://purl.obolibrary.org/obo/ECAO_0107300 primary podia http://purl.obolibrary.org/obo/ECAO_0107290 podia http://purl.obolibrary.org/obo/ECAO_0107320 secondary podia http://purl.obolibrary.org/obo/ECAO_0107290 podia http://purl.obolibrary.org/obo/ECAO_0107360 juvenile spine http://purl.obolibrary.org/obo/ECAO_0107350 spine http://purl.obolibrary.org/obo/ECAO_0107370 definitive spine http://purl.obolibrary.org/obo/ECAO_0107350 spine http://purl.obolibrary.org/obo/ECAO_0107470 ovary http://purl.obolibrary.org/obo/ECAO_0107460 gonad http://purl.obolibrary.org/obo/ECAO_0107480 testis http://purl.obolibrary.org/obo/ECAO_0107460 gonad http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. http://purl.obolibrary.org/obo/CHEBI_50906 role A role is particular behaviour which a material entity may exhibit. http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A particle smaller than an atom. http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/ECAO_0000010 Life cycle phase A temporal phase encompassing some part of the life cycle of an organism. http://purl.obolibrary.org/obo/ECAO_0000020 gametogenesis phase Biological process during which certain cells of a female or male individual (parent) are transformed into specialized reproductive cells (gametes) that will initiate development of a progeny individual (offspring) upon fertilization. http://purl.obolibrary.org/obo/ECAO_0000030 oogenesis period Period during which female gametes (or oocytes, or eggs) develop and mature from primordial female germ cells to generate cells competent to further development upon fertilization by a mature spermatozoid. http://purl.obolibrary.org/obo/ECAO_0000040 previtellogenic primary oocyte stage A female gamete that is small in size, i.e. about 10 microm in diameter, and that is at the previtellogenic stage. http://purl.obolibrary.org/obo/ECAO_0000130 embryogenesis phase The phase of the life cycle that begins with fertilization, continues with the formation and maturation of the embryo, and ends with the opening of the mouth, the onset of feeding, and the beginning of the growth of the organism. http://purl.obolibrary.org/obo/ECAO_0000150 cleavage period The period that immediately follows fertilization and is characterized by rapid, synchronous mitotic cell divisions in the absence of cell growth. Cleavage culminates in the formation of a hollow, spherical, multicellular, monolayered embryo (a blastula) with a hollow cavity (the blastocoel) in the center. http://purl.obolibrary.org/obo/ECAO_0000440 larval development phase The phase of the life cycle that begins when the mouth opens and the larva starts to feed, continues through the growth and maturation of the larva, and ends with metamorphosis. http://purl.obolibrary.org/obo/ECAO_0000530 adulthood phase The phase of the life cycle that begins after metamorphosis, continues through the growth and maturation of the juvenile, and culminates in the formation of a sexually mature adult that produces functional gametes http://purl.obolibrary.org/obo/BFO_0000001 entity http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/NCBITaxon_1 root http://purl.obolibrary.org/obo/ECAO_0000009 Life cycle http://purl.obolibrary.org/obo/ECAO_00000000 root node http://purl.obolibrary.org/obo/RO_0000052 characteristic of http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of inheres_in a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence. http://purl.obolibrary.org/obo/RO_0000079 function of http://purl.obolibrary.org/obo/RO_0000052 characteristic of is function of a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000080 quality of http://purl.obolibrary.org/obo/RO_0000052 characteristic of quality_of a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000085 has function http://purl.obolibrary.org/obo/RO_0000053 has characteristic has_function a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000086 has quality http://purl.obolibrary.org/obo/RO_0000053 has characteristic has_quality a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/RO_0002131 overlaps has_part a core relation that holds between a whole and its part http://purl.obolibrary.org/obo/RO_0000087 has role http://purl.obolibrary.org/obo/RO_0000053 has characteristic has_role a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002327 enables http://purl.obolibrary.org/obo/RO_0002215 capable of is executing c enables p iff c is capable of p and c acts to execute p. http://purl.obolibrary.org/obo/RO_0002409 indirectly negatively regulates http://purl.obolibrary.org/obo/RO_0012012 indirectly regulates indirectly inhibits p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q. http://purl.obolibrary.org/obo/RO_0002436 molecularly interacts with http://purl.obolibrary.org/obo/RO_0002434 interacts with molecularly binds with An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. http://purl.obolibrary.org/obo/RO_0002449 directly negatively regulates activity of http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of directly inhibits The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. http://purl.obolibrary.org/obo/BFO_0000062 preceded by http://purl.obolibrary.org/obo/RO_0002086 ends after preceded_by x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0000081 role of http://purl.obolibrary.org/obo/RO_0000052 characteristic of role_of a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002131 overlaps part_of a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/RO_0002233 has input http://purl.obolibrary.org/obo/RO_0000057 has participant consumes p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of http://purl.obolibrary.org/obo/RO_0002502 depends on inheres in part of q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. http://purl.obolibrary.org/obo/RO_0002215 capable of http://purl.obolibrary.org/obo/RO_0002216 capable of part of has function realized in A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. http://purl.obolibrary.org/obo/RO_0002331 involved in http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of enables part of c involved_in p if and only if c enables some process p', and p' is part of p http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process involved in or reguates c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p http://purl.obolibrary.org/obo/RO_0002216 capable of part of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process has function in c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. http://purl.obolibrary.org/obo/RO_0002329 part of structure that is capable of http://purl.obolibrary.org/obo/RO_0002328 functionally related to 0 this relation holds between c and p when c is part of some c', and c' is capable of p. http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes influences (processual) p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q. http://purl.obolibrary.org/obo/RO_0002407 indirectly positively regulates http://purl.obolibrary.org/obo/RO_0012012 indirectly regulates indirectly activates p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q. http://purl.obolibrary.org/obo/RO_0002450 directly positively regulates activity of http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of directly activates The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. http://purl.obolibrary.org/obo/RO_0004009 has primary input http://purl.obolibrary.org/obo/RO_0002233 has input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. http://purl.obolibrary.org/obo/RO_0002025 has effector activity http://purl.obolibrary.org/obo/RO_0002017 has component activity A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure http://purl.obolibrary.org/obo/RO_0000057 has participant p has anatomical participant c iff p has participant c, and c is an anatomical entity http://purl.obolibrary.org/obo/RO_0002100 has soma location http://purl.obolibrary.org/obo/RO_0002131 overlaps Relation between a neuron and a material anatomical entity that its soma is part of. http://purl.obolibrary.org/obo/RO_0002160 only in taxon http://purl.obolibrary.org/obo/RO_0002162 in taxon x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by http://purl.obolibrary.org/obo/RO_0002324 developmentally related to Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p http://purl.obolibrary.org/obo/RO_0002234 has output http://purl.obolibrary.org/obo/RO_0000057 has participant p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. http://purl.obolibrary.org/obo/RO_0002162 in taxon http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving Inverse of developmentally preceded by http://purl.obolibrary.org/obo/RO_0002371 attached to http://purl.obolibrary.org/obo/RO_0002177 attached to part of a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving http://purl.obolibrary.org/obo/RO_0002324 developmentally related to x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). http://purl.obolibrary.org/obo/RO_0002388 has potential to directly develop into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y http://purl.obolibrary.org/obo/BSPO_0015101 in dorsal side of http://purl.obolibrary.org/obo/BFO_0000050 part of X dorsal side of Y <=> if Y is subdivided into two dorsal and ventral portions, X is part of the dorsal portion. http://purl.obolibrary.org/obo/RO_0002178 supplies http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy. http://purl.obolibrary.org/obo/RO_0002372 has muscle origin http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. http://purl.obolibrary.org/obo/RO_0002380 branching part of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y http://purl.obolibrary.org/obo/RO_0002568 has muscle antagonist http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position. http://purl.obolibrary.org/obo/RO_0002569 has branching part http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with inverse of branching part of http://purl.obolibrary.org/obo/RO_0002571 lumen of http://purl.obolibrary.org/obo/BFO_0000050 part of x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull. http://purl.obolibrary.org/obo/uberon/core#anteriorly_connected_to anteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. http://purl.obolibrary.org/obo/uberon/core#distally_connected_to distally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. http://purl.obolibrary.org/obo/uberon/core#posteriorly_connected_to posteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to proximally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. http://purl.obolibrary.org/obo/RO_0004007 has primary input or output http://purl.obolibrary.org/obo/RO_0000057 has participant p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. http://purl.obolibrary.org/obo/RO_0004008 has primary output http://purl.obolibrary.org/obo/RO_0004007 has primary input or output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/RO_0002222 temporally related to x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002000 2D boundary of http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0002002 has 2D boundary http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0002219 surrounded by http://purl.obolibrary.org/obo/RO_0002220 adjacent to x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x http://purl.obolibrary.org/obo/RO_0002220 adjacent to http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from x adjacent to y if and only if x and y share a boundary. http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of starts with http://purl.obolibrary.org/obo/RO_0002350 member of http://purl.obolibrary.org/obo/BFO_0000050 part of is member of is a mereological relation between a item and a collection. http://purl.obolibrary.org/obo/RO_0002351 has member http://purl.obolibrary.org/obo/BFO_0000051 has part has member is a mereological relation between a collection and an item. http://purl.obolibrary.org/obo/RO_0002018 has component process http://purl.obolibrary.org/obo/RO_0002180 has component w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/RO_0019000 regulates characteristic http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C. http://purl.obolibrary.org/obo/RO_0019001 positively regulates characteristic http://purl.obolibrary.org/obo/RO_0019000 regulates characteristic A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C. http://purl.obolibrary.org/obo/RO_0019002 negatively regulates characteristic http://purl.obolibrary.org/obo/RO_0019000 regulates characteristic A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C. http://purl.obolibrary.org/obo/RO_0002202 develops from http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y http://purl.obolibrary.org/obo/RO_0002176 connects http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system. http://purl.obolibrary.org/obo/RO_0002491 existence starts and ends during http://purl.obolibrary.org/obo/RO_0002492 existence ends during x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y) http://purl.obolibrary.org/obo/RO_0002333 enabled by http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of enables http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of upstream of http://purl.obolibrary.org/obo/RO_0002412 immediately causally upstream of http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of http://purl.obolibrary.org/obo/RO_0011002 regulates activity of The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. http://purl.obolibrary.org/obo/RO_0002566 causally influences http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). http://purl.obolibrary.org/obo/RO_0002490 existence overlaps http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) http://purl.obolibrary.org/obo/RO_0002252 connecting branch of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t. http://purl.obolibrary.org/obo/RO_0002253 has connecting branch http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with inverse of connecting branch of http://purl.obolibrary.org/obo/RO_0002263 acts upstream of http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. http://purl.obolibrary.org/obo/RO_0002304 causally upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q. http://purl.obolibrary.org/obo/RO_0002305 causally upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q. http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to x overlaps y iff they have some part in common. http://purl.obolibrary.org/obo/RO_0002150 continuous with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to X continuous_with Y if and only if X and Y share a fiat boundary. http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x has developmental contribution from y iff x has some part z such that z develops from y http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. http://purl.obolibrary.org/obo/RO_0000091 has disposition http://purl.obolibrary.org/obo/RO_0000053 has characteristic a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000092 disposition of http://purl.obolibrary.org/obo/RO_0000052 characteristic of inverse of has disposition http://purl.obolibrary.org/obo/BSPO_0000120 in left side of http://purl.obolibrary.org/obo/BSPO_0000126 in lateral side of X in left side of Y <=> if Y is subdivided into two left and right portions, X is part of the left portion. http://purl.obolibrary.org/obo/BSPO_0000121 in right side of http://purl.obolibrary.org/obo/BSPO_0000126 in lateral side of X in right side of Y <=> if Y is subdivided into two left and right portions, X is part of the right portion. http://purl.obolibrary.org/obo/BSPO_0000122 in posterior side of http://purl.obolibrary.org/obo/BFO_0000050 part of X posterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the posterior portion. http://purl.obolibrary.org/obo/BSPO_0000123 in anterior side of http://purl.obolibrary.org/obo/BFO_0000050 part of X anterior side of Y <=> if Y is subdivided into two anterior and posterior portions, X is part of the anterior portion. http://purl.obolibrary.org/obo/BSPO_0000124 in proximal side of http://purl.obolibrary.org/obo/BFO_0000050 part of x in proximal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the proximal portion. http://purl.obolibrary.org/obo/BSPO_0000125 in distal side of http://purl.obolibrary.org/obo/BFO_0000050 part of x in distal side of y <=> if y is subdivided into two proximal and distal portions, y is part of the distal portion. http://purl.obolibrary.org/obo/BSPO_0000126 in lateral side of http://purl.obolibrary.org/obo/BFO_0000050 part of X in lateral side of Y <=> if X is in left side of Y or X is in right side of Y. X is often, but not always a paired structure http://purl.obolibrary.org/obo/BSPO_0001106 proximalmost part of http://purl.obolibrary.org/obo/BSPO_0000124 in proximal side of X proximalmost part of Y <=> X is in proximal side of Y and X is adjacent to the proximal boundary of Y http://purl.obolibrary.org/obo/BSPO_0001107 immediately deep to http://purl.obolibrary.org/obo/BSPO_0000107 deep to x immediately deep to y iff x deep_to y and x is contiguous with y. http://purl.obolibrary.org/obo/BSPO_0001108 distalmost part of http://purl.obolibrary.org/obo/BSPO_0000125 in distal side of X distalmost part of Y <=> X is in distal side of Y and X is adjacent to the distal boundary of Y http://purl.obolibrary.org/obo/BSPO_0005001 intersects midsagittal plane of http://purl.obolibrary.org/obo/BFO_0000050 part of X intersects median plane of iff X crosses the midine plane of Y. http://purl.obolibrary.org/obo/BSPO_0015014 immediately superficial to http://purl.obolibrary.org/obo/BSPO_0000108 superficial to x immediately superficial to y iff x superficial to y and x is contiguous with y. http://purl.obolibrary.org/obo/RO_0011002 regulates activity of http://purl.obolibrary.org/obo/RO_0002566 causally influences The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. http://purl.obolibrary.org/obo/RO_0012003 acts on population of http://purl.obolibrary.org/obo/RO_0000057 has participant p acts on population of c iff c' is a collection, has members of type c, and p has participant c http://purl.obolibrary.org/obo/RO_0002411 causally upstream of http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. http://purl.obolibrary.org/obo/RO_0002211 regulates http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q. http://purl.obolibrary.org/obo/RO_0002212 negatively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates (processual) p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/RO_0002213 positively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates (processual) p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/RO_0002180 has component http://purl.obolibrary.org/obo/BFO_0000051 has part w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A is spatially_disjoint_from B if and only if they have no parts in common http://purl.obolibrary.org/obo/RO_0002352 input of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has input http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has output http://purl.obolibrary.org/obo/RO_0002473 composed primarily of http://purl.obolibrary.org/obo/BFO_0000051 has part x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part http://purl.obolibrary.org/obo/BFO_0000051 has part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. http://purl.obolibrary.org/obo/RO_0002203 develops into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into inverse of develops from http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has the potential to develop into y iff x develops into y or if x is capable of developing into y http://purl.obolibrary.org/obo/RO_0002021 occurs across http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. http://purl.obolibrary.org/obo/RO_0002023 directly negatively regulated by http://purl.obolibrary.org/obo/RO_0002022 directly regulated by Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. http://purl.obolibrary.org/obo/RO_0002024 directly positively regulated by http://purl.obolibrary.org/obo/RO_0002022 directly regulated by Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. http://purl.obolibrary.org/obo/RO_0012011 indirectly causally upstream of http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q. http://purl.obolibrary.org/obo/RO_0012012 indirectly regulates http://purl.obolibrary.org/obo/RO_0012011 indirectly causally upstream of p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q. http://purl.obolibrary.org/obo/RO_0002007 bounding layer of http://purl.obolibrary.org/obo/BFO_0000050 part of X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b http://purl.obolibrary.org/obo/RO_0002177 attached to part of http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. http://purl.obolibrary.org/obo/RO_0002179 drains http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure. http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network. http://purl.obolibrary.org/obo/RO_0002376 tributary of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein. http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to http://purl.obolibrary.org/obo/RO_0002328 functionally related to A relation that holds between elements of a musculoskeletal system or its analogs. http://purl.obolibrary.org/obo/RO_0002373 has muscle insertion http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. http://purl.obolibrary.org/obo/RO_0002433 contributes to morphology of http://purl.obolibrary.org/obo/RO_0002131 overlaps p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm. http://purl.obolibrary.org/obo/RO_0002488 existence starts during http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). http://purl.obolibrary.org/obo/RO_0002489 existence starts with http://purl.obolibrary.org/obo/RO_0002488 existence starts during x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). http://purl.obolibrary.org/obo/RO_0002492 existence ends during http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). http://purl.obolibrary.org/obo/RO_0002493 existence ends with http://purl.obolibrary.org/obo/RO_0002492 existence ends during x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). http://purl.obolibrary.org/obo/RO_0002494 transformation of http://purl.obolibrary.org/obo/RO_0002202 develops from x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships http://purl.obolibrary.org/obo/RO_0002495 immediate transformation of http://purl.obolibrary.org/obo/RO_0002207 directly develops from x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t http://purl.obolibrary.org/obo/RO_0002551 has skeleton http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision. http://purl.obolibrary.org/obo/RO_0002572 luminal space of http://purl.obolibrary.org/obo/RO_0002571 lumen of s is luminal space of x iff s is lumen_of x and s is an immaterial entity http://purl.obolibrary.org/obo/RO_0002576 skeleton of http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of has skeleton http://purl.obolibrary.org/obo/uberon/core#extends_fibers_into extends_fibers_into http://purl.obolibrary.org/obo/RO_0002170 connected to X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y http://purl.obolibrary.org/obo/RO_0004031 enables subfunction http://purl.obolibrary.org/obo/RO_0002328 functionally related to Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. http://purl.obolibrary.org/obo/RO_0004034 acts upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004032 acts upstream of or within, positive effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive http://purl.obolibrary.org/obo/RO_0004035 acts upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004033 acts upstream of or within, negative effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative http://purl.obolibrary.org/obo/RO_0020101 vessel supplies blood to http://purl.obolibrary.org/obo/RO_0002178 supplies x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y. http://purl.obolibrary.org/obo/RO_0020102 vessel drains blood from http://purl.obolibrary.org/obo/RO_0002179 drains x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y. http://purl.obolibrary.org/obo/RO_0002103 synapsed by http://purl.obolibrary.org/obo/RO_0002485 receives input from Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. http://purl.obolibrary.org/obo/RO_0002120 synapsed to http://purl.obolibrary.org/obo/RO_0002486 sends output to Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to. http://purl.obolibrary.org/obo/RO_0002255 developmentally contributes to http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to inverse of has developmental contribution from http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of regulates http://purl.obolibrary.org/obo/RO_0002335 negatively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of negatively regulates http://purl.obolibrary.org/obo/RO_0002336 positively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of positively regulates http://purl.obolibrary.org/obo/RO_0002379 spatially coextensive with http://purl.obolibrary.org/obo/RO_0002131 overlaps x spatially_coextensive_with y if and inly if x and y have the same location http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes inverse of causally upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process A relationship between a material entity and a process where the material entity has some causal role that influences the process http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes http://purl.obolibrary.org/obo/RO_0002410 causally related to p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q. http://purl.obolibrary.org/obo/RO_0002584 has part structure that is capable of http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. http://purl.obolibrary.org/obo/RO_0002596 capable of regulating http://purl.obolibrary.org/obo/RO_0002500 causal agent in process Holds between c and p if and only if c is capable of some activity a, and a regulates p. http://purl.obolibrary.org/obo/RO_0002597 capable of negatively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. http://purl.obolibrary.org/obo/RO_0002598 capable of positively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. http://purl.obolibrary.org/obo/RO_0002608 process has causal agent http://purl.obolibrary.org/obo/RO_0002410 causally related to Inverse of 'causal agent in process' http://purl.obolibrary.org/obo/RO_0002015 has positive regulatory component activity http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity http://purl.obolibrary.org/obo/RO_0002017 has component activity A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. http://purl.obolibrary.org/obo/RO_0002014 has negative regulatory component activity http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. http://purl.obolibrary.org/obo/RO_0002082 simultaneous with http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time. http://purl.obolibrary.org/obo/RO_0002207 directly develops from http://purl.obolibrary.org/obo/RO_0002202 develops from Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. http://purl.obolibrary.org/obo/RO_0002210 directly develops into http://purl.obolibrary.org/obo/RO_0002203 develops into inverse of directly develops from http://purl.obolibrary.org/obo/RO_0002221 surrounds http://purl.obolibrary.org/obo/RO_0002220 adjacent to inverse of surrounded by http://purl.obolibrary.org/obo/RO_0002224 starts with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002225 develops from part of http://purl.obolibrary.org/obo/RO_0002202 develops from x develops from part of y if and only if there exists some z such that x develops from z and z is part of y http://purl.obolibrary.org/obo/RO_0002226 develops in http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops_in y if x is located in y whilst x is developing http://purl.obolibrary.org/obo/RO_0002229 ends http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of ends with http://purl.obolibrary.org/obo/RO_0002230 ends with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002231 has start location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002232 has end location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002256 developmentally induced by http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T http://purl.obolibrary.org/obo/RO_0002257 developmentally induces http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce Inverse of developmentally induced by http://purl.obolibrary.org/obo/RO_0002285 developmentally replaces http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002324 developmentally related to p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). http://purl.obolibrary.org/obo/RO_0002296 results in development of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. http://purl.obolibrary.org/obo/RO_0002298 results in morphogenesis of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. http://purl.obolibrary.org/obo/RO_0002299 results in maturation of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. http://purl.obolibrary.org/obo/RO_0002315 results in acquisition of features of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity http://purl.obolibrary.org/obo/RO_0002332 regulates levels of http://purl.obolibrary.org/obo/RO_0002328 functionally related to p regulates levels of c if p regulates some amount (PATO:0000070) of c http://purl.obolibrary.org/obo/RO_0002338 has target start location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. http://purl.obolibrary.org/obo/RO_0002339 has target end location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. http://purl.obolibrary.org/obo/RO_0002341 results in transport along http://purl.obolibrary.org/obo/RO_0002337 related via localization to Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l http://purl.obolibrary.org/obo/RO_0002342 results in transport across http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of c involved in regulation of p if c is involved in some p' and p' regulates some p http://purl.obolibrary.org/obo/RO_0002429 involved in positive regulation of http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of c involved in regulation of p if c is involved in some p' and p' positively regulates some p http://purl.obolibrary.org/obo/RO_0002430 involved in negative regulation of http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of c involved in regulation of p if c is involved in some p' and p' negatively regulates some p http://purl.obolibrary.org/obo/RO_0002570 conduit for http://purl.obolibrary.org/obo/RO_0002131 overlaps x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x. http://purl.obolibrary.org/obo/RO_0002578 directly regulates http://purl.obolibrary.org/obo/RO_0002211 regulates (processual) p directly regulates q iff p is immediately causally upstream of q and p regulates q. http://purl.obolibrary.org/obo/RO_0002586 results in breakdown of http://purl.obolibrary.org/obo/RO_0002233 has input p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c http://purl.obolibrary.org/obo/RO_0002629 directly positively regulates http://purl.obolibrary.org/obo/RO_0002578 directly regulates p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q. http://purl.obolibrary.org/obo/RO_0002630 directly negatively regulates http://purl.obolibrary.org/obo/RO_0002578 directly regulates p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q. http://purl.obolibrary.org/obo/RO_0002087 immediately preceded by http://purl.obolibrary.org/obo/BFO_0000062 preceded by starts_at_end_of http://purl.obolibrary.org/obo/RO_0002090 immediately precedes http://purl.obolibrary.org/obo/BFO_0000063 precedes meets http://purl.obolibrary.org/obo/RO_0002447 phosphorylates http://purl.obolibrary.org/obo/RO_0002436 molecularly interacts with An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y. http://purl.obolibrary.org/obo/RO_0002343 results in growth of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002297 results in formation of anatomical entity http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002287 part of developmental precursor of http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/GOREL_0002004 results in fission of http://purl.obolibrary.org/obo/RO_0000057 has participant http://purl.obolibrary.org/obo/RO_0002405 immediately causally downstream of http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002017 has component activity http://purl.obolibrary.org/obo/RO_0002018 has component process http://purl.obolibrary.org/obo/RO_0002559 causally influenced by http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities http://purl.obolibrary.org/obo/RO_0002563 interaction relation helper property http://purl.obolibrary.org/obo/RO_0002464 helper property (not for use in curation) http://purl.obolibrary.org/obo/RO_0002564 molecular interaction relation helper property http://purl.obolibrary.org/obo/RO_0002563 interaction relation helper property http://purl.obolibrary.org/obo/RO_0002481 is kinase activity http://purl.obolibrary.org/obo/RO_0002564 molecular interaction relation helper property http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002086 ends after http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/uberon/core#layer_part_of layer part of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002354 formed as result of http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/RO_0002485 receives input from http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002486 sends output to http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0004033 acts upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0004032 acts upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002322 confers advantage in http://purl.obolibrary.org/obo/RO_0002321 ecologically related to http://purl.obolibrary.org/obo/RO_0002022 directly regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities http://purl.obolibrary.org/obo/RO_0002410 causally related to http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0002588 results in assembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in http://purl.obolibrary.org/obo/RO_0002337 related via localization to http://purl.obolibrary.org/obo/RO_0002590 results in disassembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0012008 results in fusion of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0000053 has characteristic is bearer of Inverse of characteristic_of http://purl.obolibrary.org/obo/RO_0000056 participates in participates_in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000057 has participant has_participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/uberon/core#filtered_through filtered through Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to A relationship that holds via some environmental process http://purl.obolibrary.org/obo/RO_0002324 developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) http://purl.obolibrary.org/obo/uberon/core#indirectly_supplies indirectly_supplies a indirectly_supplies s iff a has a branch and the branch supplies or indirectly supplies s. http://purl.obolibrary.org/obo/uberon/core#site_of site_of c site_of p if c is the bearer of a disposition that is realized by a process that has p as part. http://purl.obolibrary.org/obo/RO_0015004 has characterizing marker set A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type. http://purl.obolibrary.org/obo/BFO_0000067 contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0001015 location of a relation between two independent continuants, the location and the target, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0017001 device utilizes material X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y. http://purl.obolibrary.org/obo/RO_0001025 located in a relation between two independent continuants, the target and the location, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0003000 produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. http://purl.obolibrary.org/obo/RO_0003001 produced by a produced_by b iff some process that occurs_in b has_output a. http://purl.obolibrary.org/obo/RO_0002434 interacts with A relationship that holds between two entities in which the processes executed by the two entities are causally connected. http://purl.obolibrary.org/obo/BSPO_0000096 anterior to x anterior to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. http://purl.obolibrary.org/obo/BSPO_0000097 distal to x distal to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal). http://purl.obolibrary.org/obo/BSPO_0000098 dorsal to x dorsal to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). http://purl.obolibrary.org/obo/BSPO_0000099 posterior to x posterior to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that extends through an organism from head end to opposite end of body or tail. http://purl.obolibrary.org/obo/BSPO_0000100 proximal to x proximal to y iff x is closer to the point of attachment with the body than y. http://purl.obolibrary.org/obo/BSPO_0000102 ventral to x ventral to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that extends through an organism from back (e.g. spinal column) to front (e.g. belly). http://purl.obolibrary.org/obo/BSPO_0000107 deep to Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines. http://purl.obolibrary.org/obo/BSPO_0000108 superficial to Near the outer surface of the organism. Thus, skin is superficial to the muscle layer. http://purl.obolibrary.org/obo/BFO_0000066 occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A mereological relationship or a topological relationship http://purl.obolibrary.org/obo/RO_0002328 functionally related to A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. http://purl.obolibrary.org/obo/RO_0015011 has cross section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. http://purl.obolibrary.org/obo/RO_0020105 is anatomical entity This property only applies to anatomical entities. http://purl.obolibrary.org/obo/RO_0002321 ecologically related to A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297) http://purl.obolibrary.org/obo/RO_0002134 innervates Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. http://purl.obolibrary.org/obo/RO_0002410 causally related to relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. http://purl.obolibrary.org/obo/RO_0002337 related via localization to A relationship that holds via some process of localization http://purl.obolibrary.org/obo/uberon/core#channels_from channels_from http://purl.obolibrary.org/obo/uberon/core#channels_into channels_into http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to transitively anteriorly connected to http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to transitively distally connected to http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to transitively proximally connected to http://purl.obolibrary.org/obo/RO_0002464 helper property (not for use in curation) http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage http://purl.obolibrary.org/obo/CL_4030045 lacks_part http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/CL_4030046 lacks_plasma_membrane_part http://purl.obolibrary.org/obo/RO_0002502 depends on http://purl.obolibrary.org/obo/uberon/core#channel_for channel for http://purl.obolibrary.org/obo/uberon/core#protects protects http://purl.obolibrary.org/obo/uberon/core#subdivision_of subdivision of http://purl.obolibrary.org/obo/RO_0002005 innervated_by http://purl.obolibrary.org/obo/GOREL_0002003 results_in_distribution_of