Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/IDO_0000445 resistance to drug http://purl.obolibrary.org/obo/IDO_0000444 protective resistance drug resistance A protective resistance that mitigates the damaging effects of a drug. http://purl.obolibrary.org/obo/IDO_0000502 infectious disease epidemic http://purl.obolibrary.org/obo/BFO_0000015 process infectious disease outbreak A process of infectious disease realizations and for which there is a statistically significant increase in the infectious disease incidence of a population. http://purl.obolibrary.org/obo/IDO_0000406 opportunistic infectious disposition http://purl.obolibrary.org/obo/IDO_0000452 infectious disposition opportunitistic pathogenic disposition An infectious disposition to become part of a disorder only in organisms whose defenses are compromised. http://purl.obolibrary.org/obo/IDO_0000409 definitive host role http://purl.obolibrary.org/obo/IDO_0000408 symbiont host role primary host role A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis reaches developmental maturity or reproduces sexually in the host. http://purl.obolibrary.org/obo/IDO_0000410 intermediate host role http://purl.obolibrary.org/obo/IDO_0000408 symbiont host role secondary host role A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis utilizes the host to undergo a developmental stage transition, and the host is required for continuation of the partner's life cycle. http://purl.obolibrary.org/obo/IDO_0000412 dead-end host role http://purl.obolibrary.org/obo/IDO_0000408 symbiont host role incidental host role A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis has the infectious disposition but cannot be transmitted from the host to the partner's definitive host. http://purl.obolibrary.org/obo/IDO_0000436 infectious disease http://purl.obolibrary.org/obo/OGMS_0000031 disease tranmissible disease A disease whose physical basis is an infectious disorder. http://purl.obolibrary.org/obo/IDO_0000442 antibacterial disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition antibiotic disposition A disposition to kill or inhibit the reproduction of bacteria. http://purl.obolibrary.org/obo/IDO_0000448 immunity to infectious agent http://purl.obolibrary.org/obo/IDO_0000446 resistance to infectious agent protective immunity to infectious agent A resistance to infectious agent that inheres in an organism in virtue of immune system components in the extended organism. http://purl.obolibrary.org/obo/IDO_0000450 pathogenic disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition pathogenicity A disposition to initiate processes that result in a disorder. http://purl.obolibrary.org/obo/IDO_0000471 complex infection http://purl.obolibrary.org/obo/IDO_0000586 infection polymicrobial infection An infection comprised of infectious organisms from different Species. http://purl.obolibrary.org/obo/IDO_0000478 _obsolete_chronic quality of infection http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class persistent infection A quality that inheres in an infection in virtue of the fact that the infection persists for an extended period of time. http://purl.obolibrary.org/obo/IDO_0000481 infectious disease incidence proportion http://purl.obolibrary.org/obo/BFO_0000019 quality cumulative incidence of infectious disease A quality that inheres in an organism population and is the proportion of members of the population not experiencing an infectious disease course at the beginning of a specified period of time and in whom the infectious disease begins during the specified period of time. http://purl.obolibrary.org/obo/IDO_0000482 infection incidence proportion http://purl.obolibrary.org/obo/BFO_0000019 quality cumulative incidence of infection A quality that inheres in an organism population and is the proportion of members of the population not infected at the beginning of a specified period of time who become infected during the specified period of time. http://purl.obolibrary.org/obo/IDO_0000498 active immunization against infectious agent http://purl.obolibrary.org/obo/IDO_0000497 immunization against infectious agent inoculation An immunization that begins with exposure of an organism to antigen and results in immunity against an infectious agent. http://purl.obolibrary.org/obo/IDO_0000514 susceptible population http://purl.obolibrary.org/obo/IDO_0000509 organism population at-risk population An organism population whose members are not infected with an infectious agent and who lack immunity to the infectious agent. http://purl.obolibrary.org/obo/IDO_0000515 normal resident microbiota population http://purl.obolibrary.org/obo/IDO_0000509 organism population normal resident microflora population An organism population whose members are participating in non-parasitic symbiosis with a particular host. http://purl.obolibrary.org/obo/IDO_0000530 primary pathogen http://purl.obolibrary.org/obo/IDO_0000596 infectious agent principal pathogen An infectious agent with a primary infectious disposition. http://purl.obolibrary.org/obo/IDO_0000532 definitive host http://purl.obolibrary.org/obo/IDO_0000531 host primary host An organism bearing a definitive host role. http://purl.obolibrary.org/obo/IDO_0000533 intermediate host http://purl.obolibrary.org/obo/IDO_0000531 host secondary host A organism bearing an intermediate host role. http://purl.obolibrary.org/obo/IDO_0000535 dead-end host http://purl.obolibrary.org/obo/IDO_0000531 host incidental host An organism bearing a dead-end host role. http://purl.obolibrary.org/obo/IDO_0000546 _obsolete_end reservoir of infectious agent http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class dead-end reservoir of infectious agent A material entity bearing an end reservoir of infectious agent role. http://purl.obolibrary.org/obo/IDO_0000548 invasion factor http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity invasin A biological macromolecule that has an invasion disposition. http://purl.obolibrary.org/obo/IDO_0000557 adhesion factor http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity adhesion molecule A biological macromolecule that has an adhesion disposition. http://purl.obolibrary.org/obo/IDO_0000562 antibacterial http://purl.obolibrary.org/obo/BFO_0000040 material entity antibiotic A material entity bearing an antibacterial disposition. http://purl.obolibrary.org/obo/IDO_0000563 microbicide http://purl.obolibrary.org/obo/IDO_0000558 antimicrobial microbicidal [entity] A material entity with an antimicrobial disposition that is realized in a process of killing microorganisms. http://purl.obolibrary.org/obo/IDO_0000579 leukocyte-mediated immunity to infectious agent http://purl.obolibrary.org/obo/IDO_0000448 immunity to infectious agent cell-mediated immunity to infectious agent An immunity to infectious agent that inheres in an organism in virtue of its leukocytes. http://purl.obolibrary.org/obo/IDO_0000589 immunodeficient organism http://purl.obolibrary.org/obo/OBI_0100026 organism immunocompromised organism An organism that has an immunodeficiency. http://purl.obolibrary.org/obo/IDO_0000590 chronic infectious disease course http://purl.obolibrary.org/obo/IDO_0000495 infectious disease course persistent infectious disease course An infectious disease course that unfolds over a long period of time. http://purl.obolibrary.org/obo/IDO_0000621 acquired immunity to infectious agent http://purl.obolibrary.org/obo/IDO_0000448 immunity to infectious agent immune memory An immunity to infectious agent that inheres in an organism in virtue of antigen receptors encoded by somatically diversified genes in the organism's genome and expressed by cells that have undergone selection during a primary immune response in that organism. http://purl.obolibrary.org/obo/IDO_0000628 chronic infection http://purl.obolibrary.org/obo/IDO_0000586 infection persistent infection An infection that persists for an extended period of time. http://purl.obolibrary.org/obo/IDO_0000630 hospital-acquired infection http://purl.obolibrary.org/obo/IDO_0000586 infection nosocomial infection An infection resulting from a transmission process that unfolds in a hospital. http://purl.obolibrary.org/obo/IDO_0000651 primary immunodeficiency http://purl.obolibrary.org/obo/IDO_0000617 immunodeficiency congenital immunodeficiency An immunodeficiency that exists in an organism because of a genetic predisposition. http://purl.obolibrary.org/obo/IDO_0000654 opportunistic pathogen http://purl.obolibrary.org/obo/IDO_0000596 infectious agent opportunist An infectious agent with an opportunistic infectious disposition. http://purl.obolibrary.org/obo/IDO_0001003 infection-based immunosuppression http://purl.obolibrary.org/obo/IDO_0000612 pathologic immunosuppression A pathologic immunosuppression process which arises as the result of an infection and is initiated or dysregulated by the infectious agent population. http://purl.obolibrary.org/obo/IDO_0001004 HIV-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001003 infection-based immunosuppression An infection-based immunosuppression process which arises as the result of an HIV infection. http://purl.obolibrary.org/obo/IDO_0001005 pathologically immunosuppressed organism http://purl.obolibrary.org/obo/IDO_0000456 immunosuppressed organism An immunosuppressed organism that is experiencing pathologic immunosuppression. http://purl.obolibrary.org/obo/IDO_0001006 immunosuppressed organism experiencing infection-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001005 pathologically immunosuppressed organism A pathologically immunosuppressed organism that is experiencing infection-based immunosuppression. http://purl.obolibrary.org/obo/IDO_0001007 immunosuppressed organism experiencing HIV-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001006 immunosuppressed organism experiencing infection-based immunosuppression A pathologically immunosuppressed organism that is experiencing HIV-based immunosuppression. http://purl.obolibrary.org/obo/IDO_0001008 immunosuppressed human experiencing HIV-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001007 immunosuppressed organism experiencing HIV-based immunosuppression An immunosuppressed organism that is a human experiencing HIV-based immunosuppression. http://purl.obolibrary.org/obo/IDO_0001009 drug-based immunosuppression http://purl.obolibrary.org/obo/IDO_0000612 pathologic immunosuppression A pathologic immunosuppression process which arises as the result of treatment with a drug that attenuates immune responses. http://purl.obolibrary.org/obo/IDO_0001010 chronic systemic steroid use-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001009 drug-based immunosuppression A drug-based immunosuppression process that results from chronic systemic steroid use. http://purl.obolibrary.org/obo/IDO_0001011 immunosuppressed organism experiencing drug-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001005 pathologically immunosuppressed organism A pathologically immunosuppressed organism that is experiencing drug-based immunosuppression. http://purl.obolibrary.org/obo/IDO_0001012 immunosuppressed organism experiencing chronic systemic steroid use-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001011 immunosuppressed organism experiencing drug-based immunosuppression a pathologically immunosuppressed organism that is experiencing chronic systemic steroid use-based immunosuppression. http://purl.obolibrary.org/obo/IDO_0001013 immunosuppressed human experiencing chronic systemic steroid use-based immunosuppression http://purl.obolibrary.org/obo/IDO_0001012 immunosuppressed organism experiencing chronic systemic steroid use-based immunosuppression An immunosuppressed organism that is a human experiencing chronic systemic steroid use-based immunosuppression. http://purl.obolibrary.org/obo/IDO_0001014 immunosuppressed human experiencing drug-based immunosuppression due to organ transplant http://purl.obolibrary.org/obo/IDO_0001011 immunosuppressed organism experiencing drug-based immunosuppression A pathologically immunosuppressed organism that is a human experiencing drug-based immunosuppression. http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity http://purl.obolibrary.org/obo/BFO_0000040 material entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. http://purl.obolibrary.org/obo/UBERON_0035944 life-death temporal boundary http://purl.obolibrary.org/obo/BFO_0000015 process A life cycle temporal boundary that marks the end of the life cycle of the organism. http://purl.obolibrary.org/obo/BFO_0000002 continuant http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that has temporal parts and that happens, unfolds or develops through time. http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. http://purl.obolibrary.org/obo/BFO_0000005 obsolete dependent continuant http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class A continuant that is either dependent on one or other independent continuant bearers or inheres in or is borne by other entities. http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. http://purl.obolibrary.org/obo/BFO_0000035 process boundary http://purl.obolibrary.org/obo/BFO_0000003 occurrent p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. http://purl.obolibrary.org/obo/BFO_0000140 continuant fiat boundary http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001]) http://purl.obolibrary.org/obo/BFO_0000144 process profile http://purl.obolibrary.org/obo/BFO_0000015 process b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002]) http://purl.obolibrary.org/obo/BFO_0000145 relational quality http://purl.obolibrary.org/obo/BFO_0000019 quality b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001]) http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data item data about an ontology part is a data item about a part of an ontology, for example a term http://purl.obolibrary.org/obo/IAO_0000225 obsolescence reason specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000409 denotator type http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part A denotator type indicates how a term should be interpreted from an ontological perspective. http://purl.obolibrary.org/obo/IDO_0000586 infection http://purl.obolibrary.org/obo/BFO_0000040 material entity A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population. http://purl.obolibrary.org/obo/IDO_0000666 human pathogenicity disposition http://purl.obolibrary.org/obo/IDO_0000450 pathogenic disposition A disposition to initiate processes that result in a disorder in a human organism. http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. http://purl.obolibrary.org/obo/OGMS_0000031 disease http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. http://purl.obolibrary.org/obo/OGMS_0000063 disease course http://purl.obolibrary.org/obo/BFO_0000015 process The totality of all processes through which a given disease instance is realized. http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. http://purl.obolibrary.org/obo/CL_0000738 leukocyte http://purl.obolibrary.org/obo/CL_0000000 cell An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/UBERON_0000178 blood http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A fluid that is composed of blood plasma and erythrocytes. http://purl.obolibrary.org/obo/GO_0051234 establishment of localization http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0065007 biological regulation http://purl.obolibrary.org/obo/BFO_0000015 process Any process that modulates a measurable attribute of any biological process, quality or function. http://purl.obolibrary.org/obo/IDO_0000444 protective resistance http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition that inheres in a material entity in virtue of the fact that the entity has a part (e.g. a gene product), which itself has a disposition to mitigate damage to the entity. http://purl.obolibrary.org/obo/IDO_0000509 organism population http://purl.obolibrary.org/obo/BFO_0000027 object aggregate An aggregate of organisms of the same Species. http://purl.obolibrary.org/obo/IDO_0000531 host http://purl.obolibrary.org/obo/OBI_0100026 organism An organism bearing a host role. http://purl.obolibrary.org/obo/IDO_0000569 asymptomatic host of infectious agent http://purl.obolibrary.org/obo/IDO_0000537 infectious agent host An organism that is host to an infectious agent and has no symptoms of the infectious disease associated with the infectious agent. http://purl.obolibrary.org/obo/IDO_0000581 antibiotic resistance http://purl.obolibrary.org/obo/IDO_0000445 resistance to drug A resistance to drug that mitigates the damaging effects of an antibiotic. http://purl.obolibrary.org/obo/IDO_0000629 host role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by an organism in virtue of the fact that it's extended organism contains a material entity other than the organism. http://purl.obolibrary.org/obo/OGMS_0000087 extended organism http://purl.obolibrary.org/obo/BFO_0000027 object aggregate An object aggregate consisting of an organism and all material entities located within the organism, overlapping the organism, or occupying sites formed in part by the organism. http://purl.obolibrary.org/obo/TRANS_0000000 transmission process http://purl.obolibrary.org/obo/BFO_0000015 process A process that is the means during which the pathogen is transmitted directly or indirectly from its natural reservoir, a susceptible host or source to a new host. http://purl.obolibrary.org/obo/TRANS_0000002 indirect http://purl.obolibrary.org/obo/TRANS_0000000 transmission process Indirect transmission is a transmission process during which the pathogen is indirectly transferred from a reservoir, source or host to another host by intermediary vehicles, vectors or as airborne dust particles. http://purl.obolibrary.org/obo/GO_0000003 reproduction http://purl.obolibrary.org/obo/GO_0008150 biological_process The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0006955 immune response Any process involved in the carrying out of an immune response by a leukocyte. http://purl.obolibrary.org/obo/GO_0006955 immune response http://purl.obolibrary.org/obo/GO_0008150 biological_process Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. http://purl.obolibrary.org/obo/GO_0006959 humoral immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated through a body fluid. http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/BFO_0000015 process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0032991 macromolecular complex http://purl.obolibrary.org/obo/BFO_0000040 material entity A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. http://purl.obolibrary.org/obo/GO_0040007 growth http://purl.obolibrary.org/obo/GO_0008150 biological_process The increase in size or mass of an entire organism, a part of an organism or a cell. http://purl.obolibrary.org/obo/GO_0045087 innate immune response http://purl.obolibrary.org/obo/GO_0006955 immune response Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0019814 immunoglobulin complex http://purl.obolibrary.org/obo/GO_0032991 macromolecular complex A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. http://purl.obolibrary.org/obo/GO_0019815 B cell receptor complex http://purl.obolibrary.org/obo/GO_0032991 macromolecular complex An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins. http://purl.obolibrary.org/obo/GO_0044406 adhesion of symbiont to host http://purl.obolibrary.org/obo/GO_0008150 biological_process The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044409 entry into host http://purl.obolibrary.org/obo/GO_0051704 multi-organism process Penetration by an organism into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0042101 T cell receptor complex http://purl.obolibrary.org/obo/GO_0032991 macromolecular complex A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. http://purl.obolibrary.org/obo/GO_0043093 FtsZ-dependent cytokinesis http://purl.obolibrary.org/obo/GO_0000003 reproduction A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells. http://purl.obolibrary.org/obo/GO_0044411 entry into host through host barriers http://purl.obolibrary.org/obo/GO_0044409 entry into host Penetration by an organism into its host organism via active breaching of the physical barriers of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0048525 negative regulation of viral process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant. http://purl.obolibrary.org/obo/GO_0051704 multi-organism process http://purl.obolibrary.org/obo/GO_0008150 biological_process A biological process which involves another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0085030 mutualism http://purl.obolibrary.org/obo/GO_0044403 symbiosis, encompassing mutualism through parasitism An interaction between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other. http://purl.obolibrary.org/obo/GO_0085031 commensalism http://purl.obolibrary.org/obo/GO_0044403 symbiosis, encompassing mutualism through parasitism An interaction between two organisms living together in more or less intimate association in a relationship in which one benefits and the other is unaffected. http://purl.obolibrary.org/obo/GO_0044403 symbiosis, encompassing mutualism through parasitism http://purl.obolibrary.org/obo/GO_0051704 multi-organism process An interaction between two organisms living together in more or less intimate association. Microscopic symbionts are often referred to as endosymbionts. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity A part of a multicellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a multicellular organism with granularity above the level of a protein complex. http://purl.obolibrary.org/obo/IDO_0000004 _obsolete_virulence http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'the degree of pathogenicitynnpathogenicity and virulence are used in some communities as synonyms.'-ID[O]:0000004: the degree of pathogenicitynnpathogenicity and virulence are used in some communities as synonyms. http://purl.obolibrary.org/obo/IDO_0000009 _obsolete_latency http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'infection has occurred, but it might not have manifested itselfnquality of being in a non replicative statentime to manifest itself na pathogen when it is in a non replicative state'-ID[O]:0000009: infection has occurred, but it might not have manifested itselfnquality of being in a non replicative statentime to manifest itself na pathogen when it is in a non replicative state http://purl.obolibrary.org/obo/IDO_0000019 _obsolete_prevalence http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'total number of cases of a particular disease at a given time in a particular population divided by the number of individuals in that particular populationnnthe burden of a disease in a population'-ID[O]:0000019: total number of cases of a particular disease at a given time in a particular population divided by the number of individuals in that particular populationnnthe burden of a disease in a population http://purl.obolibrary.org/obo/IDO_0000025 _obsolete_pathogenicity http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'the ability of the biotic entity to cause disease in a host of a given typenndo we need to say damage instead of disease?nnpathogenicity and virulence are used as synonyms in some communities'-ID[O]:0000025: the ability of the biotic entity to cause disease in a host of a given typenndo we need to say damage instead of disease?nnpathogenicity and virulence are used as synonyms in some communities http://purl.obolibrary.org/obo/IDO_0000029 _obsolete_incidence http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'number of new cases in a given period of time'-ID[O]:0000029: number of new cases in a given period of time http://purl.obolibrary.org/obo/IDO_0000040 _obsolete_virulence factor http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'role played by a portion of substance to promote virulencennmagnitudendegree of pathogenesis'-ID[O]:0000040: role played by a portion of substance to promote virulencennmagnitudendegree of pathogenesis http://purl.obolibrary.org/obo/IDO_0000048 _obsolete_symptom http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'look at mathias's ontology of cancer to get all the subterms...its under quality there'-ID[O]:0000048: look at mathias's ontology of cancer to get all the subterms...its under quality there http://purl.obolibrary.org/obo/IDO_0000054 _obsolete_colonization factor http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'role played by portion of physical substance which promotes colonization'-ID[O]:0000054: role played by portion of physical substance which promotes colonization http://purl.obolibrary.org/obo/IDO_0000055 _obsolete_adhesion factor http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'role played by portion of physical substance utilized by an organism in order to establish adherence to a surface in a host'-ID[O]:0000055: role played by portion of physical substance utilized by an organism in order to establish adherence to a surface in a host http://purl.obolibrary.org/obo/IDO_0000059 _obsolete_reservoir http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'holding place for a potential pathogen...animate or inanimate'-ID[O]:0000059: holding place for a potential pathogen...animate or inanimate http://purl.obolibrary.org/obo/IDO_0000060 _obsolete_fomite http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'inanimate holder, is water a fomite or only a reservoir?'-ID[O]:0000060: inanimate holder, is water a fomite or only a reservoir? http://purl.obolibrary.org/obo/IDO_0000063 _obsolete_vector http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'holder and a carrier (actively transmits) and living: potentially make a cross product. every vector comes into contact with the target. (from one host to another?)'-ID[O]:0000063: holder and a carrier (actively transmits) and living: potentially make a cross product. every vector comes into contact with the target. (from one host to another?) http://purl.obolibrary.org/obo/IDO_0000074 _obsolete_pathogen adherence to host cell http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'create cross products for "host" and "pathogen" that will be part of this process.'-ID[O]:0000074: create cross products for "host" and "pathogen" that will be part of this process. http://purl.obolibrary.org/obo/IDO_0000083 _obsolete_transmission http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'the process by which an infectious agent passes from one organism to another organism'-ID[O]:0000083: the process by which an infectious agent passes from one organism to another organism http://purl.obolibrary.org/obo/IDO_0000084 _obsolete_pathogenesis http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'GO:nthe specific processes that generate the ability of an organism to cause disease in anothernnnThis is defined in GO so import.'-ID[O]:0000084: GO:nthe specific processes that generate the ability of an organism to cause disease in anothernnnThis is defined in GO so import. http://purl.obolibrary.org/obo/IDO_0000098 _obsolete_infectious disease http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'comment about the instances:nncollections of etiologically connected cases of infectious disease in a given population'-ID[O]:0000098: comment about the instances:nncollections of etiologically connected cases of infectious disease in a given population http://purl.obolibrary.org/obo/IDO_0000101 _obsolete_emergence http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'the process by which an infectious disease establishes itself in a new population (or at a sufficiently higher rate? higher prevalence and/or higher incidence)'-ID[O]:0000101: the process by which an infectious disease establishes itself in a new population (or at a sufficiently higher rate? higher prevalence and/or higher incidence) http://purl.obolibrary.org/obo/IDO_0000204 _obsolete_factor http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'Role played by portion of physical substance in a biological process'-ID[O]:0000204: Role played by portion of physical substance in a biological process http://purl.obolibrary.org/obo/IDO_0000205 _obsolete_colonization http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'the process by which a biotic entity establishes multiple copies of itself in a new environment (including an organismal environment).nnfix idn"native" environment term'-ID[O]:0000205: the process by which a biotic entity establishes multiple copies of itself in a new environment (including an organismal environment).nnfix idn"native" environment term http://purl.obolibrary.org/obo/IDO_0000208 _obsolete_seroprevalence http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'prevalence as measured by antibody'-ID[O]:0000208: prevalence as measured by antibody http://purl.obolibrary.org/obo/IDO_0000209 _obsolete_dormancy http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'quality [state] of an organism that during its life cycle in which its growth. development, metabolism, etc is temporarily suspended nnnsuspended state, non-replicative state, resting state'-ID[O]:0000209: quality [state] of an organism that during its life cycle in which its growth. development, metabolism, etc is temporarily suspended nnnsuspended state, non-replicative state, resting state http://purl.obolibrary.org/obo/IDO_0000212 _obsolete_susceptibility http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'can change depending on environmentnnwhere should susceptibility factors go?'-ID[O]:0000212: can change depending on environmentnnwhere should susceptibility factors go? http://purl.obolibrary.org/obo/IDO_0000219 _obsolete_incubation period http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'agent is incubated?ndisease is incubated?'-ID[O]:0000219: agent is incubated?ndisease is incubated? http://purl.obolibrary.org/obo/IDO_0000221 _obsolete_infectious disease progression http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'the unfolding or course of infectious diseasennwhat do we say about infectious disease that always remain latent nwhat about when a pathogen continues its progression nnwe need to think about whether we need a term called stagenlife cycle?nprogression?ndevelopment?'-ID[O]:0000221: the unfolding or course of infectious diseasennwhat do we say about infectious disease that always remain latent nwhat about when a pathogen continues its progression nnwe need to think about whether we need a term called stagenlife cycle?nprogression?ndevelopment? http://purl.obolibrary.org/obo/IDO_0000226 _obsolete_pathogen life cycle http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'is this just the part of the life cycle of the biotic entity that has role pathogen for the period of time while it has role pathogen?nncan include phases in the existence of the entity before it becomes a pathogen'-ID[O]:0000226: is this just the part of the life cycle of the biotic entity that has role pathogen for the period of time while it has role pathogen?nncan include phases in the existence of the entity before it becomes a pathogen http://purl.obolibrary.org/obo/IDO_0000227 _obsolete_dormancy period http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'is a period a process?'-ID[O]:0000227: is a period a process? http://purl.obolibrary.org/obo/IDO_0000306 _obsolete_fitness http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 'is a quality relating to both bacteria and host'-ID[O]:0000306: is a quality relating to both bacteria and host http://purl.obolibrary.org/obo/IDO_0000400 symbiont role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by an organism in symbiosis. http://purl.obolibrary.org/obo/IDO_0000401 mutualist role http://purl.obolibrary.org/obo/IDO_0000400 symbiont role A symbiont role borne by an organism in virtue of the fact that both symbionts derive a growth, survival, or fitness advantage from symbiosis. http://purl.obolibrary.org/obo/IDO_0000402 commensal role http://purl.obolibrary.org/obo/IDO_0000400 symbiont role A symbiont role borne by an organism in virtue of the fact that it derives a growth, survival, or fitness advantage from symbiosis, but the other symbiont is neither advantaged nor disadvantaged. http://purl.obolibrary.org/obo/IDO_0000403 parasite role http://purl.obolibrary.org/obo/IDO_0000400 symbiont role A symbiont role borne by an organism in virtue of the fact that it derives a growth, survival, or fitness advantage from symbiosis while the other symbiont's growth, survival, or fitness is reduced. http://purl.obolibrary.org/obo/IDO_0000404 infectious agent role http://purl.obolibrary.org/obo/IDO_0000405 pathogen role A role borne by an infectious agent when contained in a host in which its infectious disposition can be realized. http://purl.obolibrary.org/obo/IDO_0000405 pathogen role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by pathogen in virtue of the fact that it or one of its products is sufficiently close to an organism towards which it has the pathogenic disposition to allow realization of the pathogenic disposition. http://purl.obolibrary.org/obo/IDO_0000407 primary infectious disposition http://purl.obolibrary.org/obo/IDO_0000452 infectious disposition An infectious disposition to become part of a disorder in organisms that have intact defenses. http://purl.obolibrary.org/obo/IDO_0000408 symbiont host role http://purl.obolibrary.org/obo/IDO_0000629 host role A host role borne by an organism in virtue of the fact that its extended organism contains a second organism and provides an environment supportive for the survival, growth, maturation, or reproduction of that organism. http://purl.obolibrary.org/obo/IDO_0000411 paratenic host role http://purl.obolibrary.org/obo/IDO_0000408 symbiont host role A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis utilizes the host to undergo a developmental stage transition, but the host is not required for continuation of the partner's life cycle. http://purl.obolibrary.org/obo/IDO_0000413 parasite host role http://purl.obolibrary.org/obo/IDO_0000408 symbiont host role A symbiont host role borne by an organism in virtue of the fact that its partner in symbiosis derives from the host a growth, survival, or fitness advantage while the host's growth, survival, or fitness is reduced. http://purl.obolibrary.org/obo/IDO_0000414 infectious agent host role http://purl.obolibrary.org/obo/IDO_0000415 pathogen host role A pathogen host role borne by an organism in virtue of the fact that its extended organism contains an infectious agent. http://purl.obolibrary.org/obo/IDO_0000415 pathogen host role http://purl.obolibrary.org/obo/IDO_0000629 host role A host role borne by an organism in virtue of the fact that its extended organism contains a pathogen. http://purl.obolibrary.org/obo/IDO_0000416 infectious agent carrier role http://purl.obolibrary.org/obo/IDO_0000414 infectious agent host role An infectious agent host role borne by an organism in virtue of the fact that its extended organism contains an infectious agent, the infectious agent has the infectious disposition towards the host, and the host has no symptoms of the infectious disease caused by the infectious agent. http://purl.obolibrary.org/obo/IDO_0000417 infectious agent transporter role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by a material entity in virtue of the fact that an infectious agent is located in or on the entity and the entity has the capability to transfer (either actively or passively) the infectious agent from one location to another. http://purl.obolibrary.org/obo/IDO_0000418 infectious agent vector role http://purl.obolibrary.org/obo/IDO_0000417 infectious agent transporter role An infectious agent transporter role that is borne by an organism active in the transfer of an infectious agent to an organism of another Species and in which the agent is infectious. http://purl.obolibrary.org/obo/IDO_0000419 mechanical vector of infectious agent role http://purl.obolibrary.org/obo/IDO_0000418 infectious agent vector role An infectious agent vector role borne by an organism in virtue of the fact that the infectious agent does not multiply in or on the vector. http://purl.obolibrary.org/obo/IDO_0000420 biological vector of infectious agent role http://purl.obolibrary.org/obo/IDO_0000418 infectious agent vector role An infectious agent vector role borne by an organism in virtue of the fact that the infectious agent multiplies in the vector. http://purl.obolibrary.org/obo/IDO_0000421 infectious agent vehicle role http://purl.obolibrary.org/obo/IDO_0000417 infectious agent transporter role An infectious agent transporter role borne by an entity in virtue of the fact that the entity is not a complete organism. http://purl.obolibrary.org/obo/IDO_0000422 biological vehicle of infectious agent role http://purl.obolibrary.org/obo/IDO_0000421 infectious agent vehicle role An infectious agent vehicle role borne by an entity in virtue of the fact that the entity is living or contains living cells other than those that have the infectious disposition. http://purl.obolibrary.org/obo/IDO_0000423 fomite role http://purl.obolibrary.org/obo/IDO_0000421 infectious agent vehicle role An infectious agent vehicle role borne by an entity in virtue of the fact that the entity is not alive. http://purl.obolibrary.org/obo/IDO_0000424 reservoir of infectious agent role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by a material entity in virtue of the fact that it is a habitat in which infectious agents can persist and multiply and from which they can be transmitted in virtue of prevailing practices of potential hosts. http://purl.obolibrary.org/obo/IDO_0000425 virulence factor disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition borne by a biological macromolecule produced by a pathogen that is a disposition to undergo processes that increase the pathogen's virulence. http://purl.obolibrary.org/obo/IDO_0000426 toxin disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to cause I) malfunction of cells, ii) damage to extracellular matrix, or iii) damage of cells to a degree that can result in cell death. http://purl.obolibrary.org/obo/IDO_0000427 exotoxin disposition http://purl.obolibrary.org/obo/IDO_0000426 toxin disposition A toxin disposition to damage cells or extracellular matrix by a direct enzymatic process. http://purl.obolibrary.org/obo/IDO_0000428 enterotoxin disposition http://purl.obolibrary.org/obo/IDO_0000427 exotoxin disposition An exotoxin disposition to damage cells of the host intestinal mucosa. http://purl.obolibrary.org/obo/IDO_0000429 endotoxin disposition http://purl.obolibrary.org/obo/IDO_0000426 toxin disposition A toxin disposition that inheres in a protein or protein complex that is a structural component of a pathogen and is released from the pathogen only upon cytolysis. http://purl.obolibrary.org/obo/IDO_0000430 infectious agent portal of entry role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by an anatomical entity in virtue of the fact that it serves as the site through which an infectious agent enters a host. http://purl.obolibrary.org/obo/IDO_0000431 infectious agent portal of exit role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by an anatomical entity in virtue of the fact that it serves as the site through which an infectious agent exits a host. http://purl.obolibrary.org/obo/IDO_0000432 disinfectant role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by a material entity in virtue of the fact that it has an antimicrobial disposition and is applied to a non-living entity. http://purl.obolibrary.org/obo/IDO_0000433 antiseptic role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by a material entity in virtue of the fact that it has an antimicrobial disposition and is applied to an anatomical entity of a living organism. http://purl.obolibrary.org/obo/IDO_0000434 primary infection role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by an infectious disorder in virtue of the fact that (1) the host has at least two distinct infectious disorders, where neither arose from the other through metastasis, (2) at the time the infectious disorder was established in the host, the host had no infectious disorder, and (3) the infectious disorder increases the host's susceptibility to infectious disorders. http://purl.obolibrary.org/obo/IDO_0000435 secondary infection role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by an infectious disorder in virtue of the fact that (1) the host has at least two distinct infectious disorders, where neither arose from the other through metastasis, (2) at the time the infectious disorder was established in the host, the host had a primary infectious disorder, and (3) establishment of the infectious disorder occurs because of increased susceptibility to infectious disorders conferred by the primary infectious disorder. http://purl.obolibrary.org/obo/IDO_0000437 adhesion disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition borne by a biological macromolecule that is the disposition to participate in adherence to a host. http://purl.obolibrary.org/obo/IDO_0000438 invasion disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition borne by a biological macromolecule that is the disposition to facilitate breach of host epithelial barriers or entry into and survival in host cells. http://purl.obolibrary.org/obo/IDO_0000439 antimicrobial disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to kill or inhibit the development or reproduction of microorganisms. http://purl.obolibrary.org/obo/IDO_0000440 antiviral disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to kill or inhibit the lifecycle of viruses. http://purl.obolibrary.org/obo/IDO_0000441 antifungal disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to kill or inhibit the development or reproduction of fungal organisms. http://purl.obolibrary.org/obo/IDO_0000443 antiparasitic disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to kill or inhibit the development or reproduction of eukaryotic parasites. http://purl.obolibrary.org/obo/IDO_0000446 resistance to infectious agent http://purl.obolibrary.org/obo/IDO_0000444 protective resistance A protective resistance that inheres in an organism and mitigates the damaging effects on that organism of an infectious agent. http://purl.obolibrary.org/obo/IDO_0000447 herd immunity to infectious organism http://purl.obolibrary.org/obo/IDO_0000588 collective resistance disposition A collective resistance disposition that inheres in an organism population in virtue of the fact that the proportion of the population with immunity to an infectious agent is high resulting in a low number of transmissions from hosts in the population to susceptible individuals in the population and thereby mitigating the damaging effects of the infectious agent on the population. http://purl.obolibrary.org/obo/IDO_0000449 sterilizing immunity to infectious agent http://purl.obolibrary.org/obo/IDO_0000448 immunity to infectious agent An immunity to infectious agent that results in elimination of the infectious agent from the host. http://purl.obolibrary.org/obo/IDO_0000451 invasive disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition borne by an infectious agent that is the disposition to penetrate the epithelial barriers of an organism of another Species. http://purl.obolibrary.org/obo/IDO_0000452 infectious disposition http://purl.obolibrary.org/obo/IDO_0000450 pathogenic disposition A pathogenic disposition that inheres in an organism and is a disposition for that organism (1) to be transmitted to a host, (2) to establish itself in the host, (3) to initiate processes that result in a disorder in the host, and (4) to become part of that disorder. http://purl.obolibrary.org/obo/IDO_0000453 zoonotic disposition http://purl.obolibrary.org/obo/IDO_0000452 infectious disposition An infectious disposition that is the disposition to be transmitted from an infected, non-human host to a human host. http://purl.obolibrary.org/obo/IDO_0000454 reverse zoonotic disposition http://purl.obolibrary.org/obo/IDO_0000452 infectious disposition An infectious disposition that is the disposition to be transmitted from an infected, human host to a non-human host. http://purl.obolibrary.org/obo/IDO_0000455 collective disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition that inheres in a collection of entities in virtue of the individual dispositions of the constituents of that collection. http://purl.obolibrary.org/obo/IDO_0000456 immunosuppressed organism http://purl.obolibrary.org/obo/OBI_0100026 organism An organism that is experiencing pregnancy-induced or pathologic immunosuppression. http://purl.obolibrary.org/obo/IDO_0000457 immunocompetent organism http://purl.obolibrary.org/obo/OBI_0100026 organism An organism that has immunocompetence. http://purl.obolibrary.org/obo/IDO_0000458 contagiousness http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition that inheres in a host of infectious agent and is a disposition to transmit infectious agents to organisms of the same Species through casual contact with a high likelihood of realization. http://purl.obolibrary.org/obo/IDO_0000459 colonized host http://purl.obolibrary.org/obo/OBI_0100026 organism An organism that contains a colony in or on its extended organism. http://purl.obolibrary.org/obo/IDO_0000460 infected organism http://purl.obolibrary.org/obo/OBI_0100026 organism An organism that has an infection in or on its extended organism. http://purl.obolibrary.org/obo/IDO_0000461 co-infected organism http://purl.obolibrary.org/obo/IDO_0000460 infected organism An organism that has two infections with distinct Species of infectious agents. http://purl.obolibrary.org/obo/IDO_0000462 _obsolete_symptomatic host http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class A host exhibiting disease symptoms. http://purl.obolibrary.org/obo/IDO_0000463 infectious agent transmissibility http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an infectious agent and is the likelihood that the infectious agent will undergo a horizontal transmission process. http://purl.obolibrary.org/obo/IDO_0000464 infectivity http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an infectious agent and is the liklihood that the infectious disposition will be realized upon exposure of a susceptible organism. http://purl.obolibrary.org/obo/IDO_0000466 virulence http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an infectious agent and is the degree to which realizations of the infectious disease caused by the infectious agent become severe or fatal. http://purl.obolibrary.org/obo/IDO_0000467 susceptibility http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an entity and is the degree to which it can be harmed by another entity. http://purl.obolibrary.org/obo/IDO_0000468 susceptibility to infectious agent http://purl.obolibrary.org/obo/IDO_0000467 susceptibility A susceptibility that inheres in an organism and is the degree to which it can be harmed by an infectious agent. http://purl.obolibrary.org/obo/IDO_0000469 drug susceptibility http://purl.obolibrary.org/obo/IDO_0000467 susceptibility A susceptibility that is the degree to which an entity can be harmed or inhibited from surviving by a drug. http://purl.obolibrary.org/obo/IDO_0000470 drug susceptibility of infectious agent http://purl.obolibrary.org/obo/IDO_0000469 drug susceptibility A drug susceptibility that inheres in an infectious agent and is the degree to which the infectious agent can be harmed or inhibited from surviving by a drug. http://purl.obolibrary.org/obo/IDO_0000472 extracellular infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection for which the infectious agents that are part of the infection persist in the extracellular space of the host. http://purl.obolibrary.org/obo/IDO_0000473 intracellular infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection for which the infectious agents that are part of the infection persist inside host cells. http://purl.obolibrary.org/obo/IDO_0000474 systemic infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection for which the infectious agents that are part of the infection are distributed throughout the host. http://purl.obolibrary.org/obo/IDO_0000475 local infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection for which the infectious agents that are part of the infection are limited to a relatively small area of the host's body. http://purl.obolibrary.org/obo/IDO_0000476 focal infection http://purl.obolibrary.org/obo/IDO_0000475 local infection A local infection for which symptoms are observed in parts of the host's extended organism that are distant from the infection. http://purl.obolibrary.org/obo/IDO_0000477 acute infectious disease course http://purl.obolibrary.org/obo/IDO_0000495 infectious disease course An infectious disease course that begins soon after infection is established and progresses rapidly to severe stages. http://purl.obolibrary.org/obo/IDO_0000479 infectious disease incidence http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the number of realizations of an infectious disease for which the infectious disease course begins during a specified period of time. http://purl.obolibrary.org/obo/IDO_0000480 infection incidence http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the number of organisms in the population that become infected with an infectious agent during a specified period of time. http://purl.obolibrary.org/obo/IDO_0000483 infectious disease incidence rate http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the infectious disease incidence proportion per unit time. http://purl.obolibrary.org/obo/IDO_0000484 infection incidence rate http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the infection incidence proportion per unit time. http://purl.obolibrary.org/obo/IDO_0000485 infectious disease prevalence http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the number of realizations of an infectious disease in the population at a specified time. http://purl.obolibrary.org/obo/IDO_0000486 infection prevalence http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the number of organisms in the population infected with an infectious agent at a specified time. http://purl.obolibrary.org/obo/IDO_0000487 infectious disease lifetime prevalence http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the number of organisms in the population who have, at any point during their lives, been bearers of an infectious disease and experienced realization of the disease. http://purl.obolibrary.org/obo/IDO_0000488 infectious agent seroprevalence http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the number of organisms in the population that have antibody specific for an infectious agent in their serum at a specified time. http://purl.obolibrary.org/obo/IDO_0000489 infectious disease mortality rate http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population and is the per capita number of deaths in the population resulting from an infectious disease over a specified period of time. http://purl.obolibrary.org/obo/IDO_0000490 infectious disease endemicity http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population in virtue of the fact that infections of the type that causes an infectious disease are maintained in the population via intra-population transmission or by transmission from a local reservoir. http://purl.obolibrary.org/obo/IDO_0000491 infectious disease endemic level http://purl.obolibrary.org/obo/IDO_0000485 infectious disease prevalence An infectious disease prevalence that is typical for an infectious disease in an organism population. http://purl.obolibrary.org/obo/IDO_0000492 infectious disease endemic rate http://purl.obolibrary.org/obo/IDO_0000483 infectious disease incidence rate An infectious disease incidence rate that is typical for an infectious disease in an organism population. http://purl.obolibrary.org/obo/IDO_0000493 infectious disease hyper-endemicity http://purl.obolibrary.org/obo/IDO_0000490 infectious disease endemicity An infectious disease endemicity that inheres in an organism population in virtue of the fact that the infectious disease endemic level for an infectious disease is persistently high in the population. http://purl.obolibrary.org/obo/IDO_0000494 infectious disease sporadicity http://purl.obolibrary.org/obo/BFO_0000019 quality A quality that inheres in an organism population by virtue of the fact that realizations of an infectious disease occur in the population with a fluctuating prevalence. http://purl.obolibrary.org/obo/IDO_0000495 infectious disease course http://purl.obolibrary.org/obo/OGMS_0000063 disease course A disease course that is the realization of an infectious disease. http://purl.obolibrary.org/obo/IDO_0000496 long-term non-progressing infectious disease course http://purl.obolibrary.org/obo/IDO_0000590 chronic infectious disease course A chronic infectious disease course that does not progress to severe stages for a long period of time. http://purl.obolibrary.org/obo/IDO_0000497 immunization against infectious agent http://purl.obolibrary.org/obo/BFO_0000015 process A process by which an organism acquires immunity to an infectious agent. http://purl.obolibrary.org/obo/IDO_0000499 vaccination against infectious agent http://purl.obolibrary.org/obo/IDO_0000498 active immunization against infectious agent An active immunization that begins with exposure of an organism to a vaccine. http://purl.obolibrary.org/obo/IDO_0000500 variolation http://purl.obolibrary.org/obo/IDO_0000498 active immunization against infectious agent An active immunization that begins with exposure to smallpox in the form of a scab from a pustule and results in immunity against smallpox. http://purl.obolibrary.org/obo/IDO_0000501 passive immunization against infectious agent http://purl.obolibrary.org/obo/IDO_0000497 immunization against infectious agent An immunization that begins with transfer to an organism of molecules not produced by that organism and that confer immunity against an infectious agent. http://purl.obolibrary.org/obo/IDO_0000503 infectious disease pandemic http://purl.obolibrary.org/obo/BFO_0000015 process A process in which multiple infectious disease epidemics of the same type of infectious disease unfold over overlapping periods of time and affect organism populations located in different geographic regions, including different countries and continents. http://purl.obolibrary.org/obo/IDO_0000504 infectious disorder http://purl.obolibrary.org/obo/OGMS_0000045 disorder An infection that is clinically abnormal. http://purl.obolibrary.org/obo/IDO_0000505 viremia http://purl.obolibrary.org/obo/IDO_0000472 extracellular infection An infection that has as part virus particles located in the blood. http://purl.obolibrary.org/obo/IDO_0000506 bacteremia http://purl.obolibrary.org/obo/IDO_0000472 extracellular infection An infection that has as part bacteria located in the blood. http://purl.obolibrary.org/obo/IDO_0000507 _obsolete_septicemia http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class A bacteremia in which the baceteria are replicating. http://purl.obolibrary.org/obo/IDO_0000508 virion http://purl.obolibrary.org/obo/NCBITaxon_10239 Viruses A virus that is in its assembled state consisting of genomic material (DNA or RNA) surrounded by coating molecules. http://purl.obolibrary.org/obo/IDO_0000511 infected population http://purl.obolibrary.org/obo/IDO_0000509 organism population An organism population whose members have an infection. http://purl.obolibrary.org/obo/IDO_0000512 diseased population http://purl.obolibrary.org/obo/IDO_0000509 organism population An organism population in whose members an infectious disease is being realized. http://purl.obolibrary.org/obo/IDO_0000513 infectious agent population http://purl.obolibrary.org/obo/IDO_0000509 organism population An organism population whose members each have an infectious disposition. http://purl.obolibrary.org/obo/IDO_0000516 _obsolete_configured infectious organism population http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class An infectious organism population with a certain configuration quality (OGMS:0000039) (distributed across a spatial region (e.g., anatomical location in a host) in a particular way). Put e.g. In comments http://purl.obolibrary.org/obo/IDO_0000519 incubation period http://purl.obolibrary.org/obo/BFO_0000038 one-dimensional temporal region A continuous temporal interval beginning with the extablishment of an infectious agent colony and ending with the onset of symptoms (or infectious disease course?). http://purl.obolibrary.org/obo/IDO_0000520 communicability period http://purl.obolibrary.org/obo/BFO_0000038 one-dimensional temporal region A continuous temporal interval during which an infectious agent host bears a contagiousness disposition. http://purl.obolibrary.org/obo/IDO_0000522 symbiont http://purl.obolibrary.org/obo/OBI_0100026 organism An organism bearing a symbiont role. http://purl.obolibrary.org/obo/IDO_0000523 obligatory symbiont http://purl.obolibrary.org/obo/IDO_0000522 symbiont An organism that can only reach developmental maturity, replicate, or persist in symbiosis. http://purl.obolibrary.org/obo/IDO_0000524 mutualist http://purl.obolibrary.org/obo/IDO_0000522 symbiont An organism bearing a mutualist role. http://purl.obolibrary.org/obo/IDO_0000525 commensal http://purl.obolibrary.org/obo/IDO_0000522 symbiont An organism bearing a commensal role. http://purl.obolibrary.org/obo/IDO_0000526 parasite http://purl.obolibrary.org/obo/IDO_0000522 symbiont A organism bearing a parasite role. http://purl.obolibrary.org/obo/IDO_0000527 _obsolete_infectious organism http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class An infectious agent that is an organism. http://purl.obolibrary.org/obo/IDO_0000528 pathogen http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity with a pathogenic disposition. http://purl.obolibrary.org/obo/IDO_0000534 paratenic host http://purl.obolibrary.org/obo/IDO_0000531 host An organism bearing a paratenic host role. http://purl.obolibrary.org/obo/IDO_0000536 parasite host http://purl.obolibrary.org/obo/IDO_0000531 host An organism bearing a parasite host role. http://purl.obolibrary.org/obo/IDO_0000537 infectious agent host http://purl.obolibrary.org/obo/IDO_0000538 pathogen host An organism bearing an infectious agent host role. http://purl.obolibrary.org/obo/IDO_0000538 pathogen host http://purl.obolibrary.org/obo/IDO_0000531 host An organism bearing a pathogen host role. http://purl.obolibrary.org/obo/IDO_0000539 infectious agent carrier http://purl.obolibrary.org/obo/IDO_0000537 infectious agent host An organism bearing the infectious agent carrier role. http://purl.obolibrary.org/obo/IDO_0000540 infectious agent vector http://purl.obolibrary.org/obo/OBI_0100026 organism An organism bearing an infectious agent vector role. http://purl.obolibrary.org/obo/IDO_0000541 mechanical vector of infectious agent http://purl.obolibrary.org/obo/IDO_0000540 infectious agent vector An infectious agent vector bearing a mechanical vector of infectious agent role. http://purl.obolibrary.org/obo/IDO_0000542 biological vector of infectious agent http://purl.obolibrary.org/obo/IDO_0000540 infectious agent vector An infectious agent vector bearing a biological vector of infectious agent role. http://purl.obolibrary.org/obo/IDO_0000543 vehicle of infectious agent http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing an infectious agent vehicle role. http://purl.obolibrary.org/obo/IDO_0000544 fomite http://purl.obolibrary.org/obo/IDO_0000543 vehicle of infectious agent A material entity bearing a fomite role. http://purl.obolibrary.org/obo/IDO_0000545 infectious agent reservoir http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing an infectious agent reservoir role. http://purl.obolibrary.org/obo/IDO_0000547 virulence factor http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A biological macromolecule produced by a pathogen and that has a virulence factor disposition. http://purl.obolibrary.org/obo/IDO_0000549 toxin http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity that has a toxin disposition. http://purl.obolibrary.org/obo/IDO_0000550 exotoxin http://purl.obolibrary.org/obo/IDO_0000549 toxin A molecular entity bearing an exotoxin disposition. http://purl.obolibrary.org/obo/IDO_0000551 enterotoxin http://purl.obolibrary.org/obo/IDO_0000550 exotoxin A molecular entity with an exotoxin disposition, the realization of which damages cells of the host intestinal mucosa. http://purl.obolibrary.org/obo/IDO_0000552 endotoxin http://purl.obolibrary.org/obo/IDO_0000549 toxin A molecular entity with a toxin disposition and that is a structural component of a pathogen and is released from the pathogen only upon cytolysis. http://purl.obolibrary.org/obo/IDO_0000553 infectious agent portal of entry http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An anatomical entity bearing an infectious agent portal of entry role. http://purl.obolibrary.org/obo/IDO_0000554 infectious agent portal of exit http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity An anatomical entity bearing an infectious agent portal of exit role. http://purl.obolibrary.org/obo/IDO_0000555 disinfectant http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing a disinfectant role. http://purl.obolibrary.org/obo/IDO_0000556 antiseptic http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing an antiseptic role. http://purl.obolibrary.org/obo/IDO_0000558 antimicrobial http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity with an antimicrobial disposition. http://purl.obolibrary.org/obo/IDO_0000559 antiviral http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing an antiviral disposition. http://purl.obolibrary.org/obo/IDO_0000560 antifungal http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing an antifungal disposition. http://purl.obolibrary.org/obo/IDO_0000561 antiparasitic http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing an antiparasitic disposition. http://purl.obolibrary.org/obo/IDO_0000564 viricide http://purl.obolibrary.org/obo/IDO_0000559 antiviral A material entity with an antiviral disposition that is realized in a process of killing viruses. http://purl.obolibrary.org/obo/IDO_0000565 microbistatic http://purl.obolibrary.org/obo/IDO_0000558 antimicrobial A material entity with an antimicrobial disposition that is realized in a process of inhibiting the growth of microorganisms. http://purl.obolibrary.org/obo/IDO_0000566 primary infection http://purl.obolibrary.org/obo/IDO_0000504 infectious disorder An infection bearing the primary infection role. http://purl.obolibrary.org/obo/IDO_0000567 secondary infection http://purl.obolibrary.org/obo/IDO_0000504 infectious disorder An infection bearing the secondary infection role. http://purl.obolibrary.org/obo/IDO_0000568 zoonosis http://purl.obolibrary.org/obo/IDO_0000436 infectious disease An infectious disease that has as its physical basis an infectious disorder composed of infectious agents that have a zoonotic disposition. http://purl.obolibrary.org/obo/IDO_0000570 subclinical infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection that is part of an asymptomatic host. http://purl.obolibrary.org/obo/IDO_0000571 resistant entity http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity that has a resistance disposition. http://purl.obolibrary.org/obo/IDO_0000572 chronic carrier of infectious agent http://purl.obolibrary.org/obo/IDO_0000539 infectious agent carrier An organism who has been bearer of the infectious agent carrier role for an extended period of time. http://purl.obolibrary.org/obo/IDO_0000573 symptomatic host of infectious agent http://purl.obolibrary.org/obo/IDO_0000537 infectious agent host An organism who is host to an infectious agent and has symptoms of the infectious disease associated with the infectious agent http://purl.obolibrary.org/obo/IDO_0000574 _obsolete_invasin http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class synonym of invasion factor http://purl.obolibrary.org/obo/IDO_0000575 _obsolete_viral latency http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000576 innate immunity to infectious agent http://purl.obolibrary.org/obo/IDO_0000448 immunity to infectious agent An immunity to infectious agent that inheres in an organism in virtue of germline encoded components that directly recognize components of potential pathogens. http://purl.obolibrary.org/obo/IDO_0000577 _obsolete_adaptive immunity to infectious agent http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class An immunity to infectious agent realized in an adaptive immune response. http://purl.obolibrary.org/obo/IDO_0000578 humoral immunity to infectious agent http://purl.obolibrary.org/obo/IDO_0000448 immunity to infectious agent An immunity to infectious agent that inheres in an organism in virtue of components of its circulating body fluid. http://purl.obolibrary.org/obo/IDO_0000580 passive immunity to infectious agent http://purl.obolibrary.org/obo/IDO_0000448 immunity to infectious agent An immunity to infectious agent that inheres in an organism in virtue of antibodies not produced by that organism. http://purl.obolibrary.org/obo/IDO_0000582 long-term non-progressor http://purl.obolibrary.org/obo/OBI_0100026 organism An organism experiencing a long-term non-progressing infectious disease course. http://purl.obolibrary.org/obo/IDO_0000583 emerging pathogen http://purl.obolibrary.org/obo/IDO_0000596 infectious agent An infectious agent whose infection incidence is increasing following its first introduction into a new host Species. http://purl.obolibrary.org/obo/IDO_0000584 cytotoxin http://purl.obolibrary.org/obo/IDO_0000549 toxin A molecular entity with a toxin disposition, the realization of which damages host cells. http://purl.obolibrary.org/obo/IDO_0000585 collective pathogenic disposition http://purl.obolibrary.org/obo/IDO_0000455 collective disposition A collective disposition to initiate processes that result in a disorder. http://purl.obolibrary.org/obo/IDO_0000587 genetic resistance to infectious agent http://purl.obolibrary.org/obo/IDO_0000446 resistance to infectious agent A resistance to infectious agent that inheres in an organism in virtue of a specific allele or combination of alleles in its genome. http://purl.obolibrary.org/obo/IDO_0000588 collective resistance disposition http://purl.obolibrary.org/obo/IDO_0000455 collective disposition A collective disposition the realization of which mitigates the damaging effects of some entity on members of the collection. http://purl.obolibrary.org/obo/IDO_0000591 _obsolete_communicable disposition http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class An infectious disposition to be transmitted directly from one human host to another. http://purl.obolibrary.org/obo/IDO_0000592 immune population http://purl.obolibrary.org/obo/IDO_0000509 organism population An organism population whose members have acquired immunity to an infectious agent. http://purl.obolibrary.org/obo/IDO_0000593 transmission period http://purl.obolibrary.org/obo/BFO_0000038 one-dimensional temporal region A continuous temporal interval during which a transmission process occurs. http://purl.obolibrary.org/obo/IDO_0000594 direct host exposure to infectious agent http://purl.obolibrary.org/obo/IDO_0000658 host exposure to infectious agent A process in which a potential host of an infectious agent comes into direct physical contact with the infectious agent. http://purl.obolibrary.org/obo/IDO_0000595 potential host of infectious agent http://purl.obolibrary.org/obo/OBI_0100026 organism An organism that has the capability to bear a host of infectious agent role. http://purl.obolibrary.org/obo/IDO_0000596 infectious agent http://purl.obolibrary.org/obo/IDO_0000528 pathogen An organism that has an infectious disposition. http://purl.obolibrary.org/obo/IDO_0000597 host exposure to environment containing infectious agent http://purl.obolibrary.org/obo/IDO_0000658 host exposure to infectious agent A process in which a potential host of an infectious agent is exposed to an environment in which the infectious agent is present and physical contact between the two can occur, but such contact is not planned. http://purl.obolibrary.org/obo/IDO_0000598 host living with infected household contact http://purl.obolibrary.org/obo/IDO_0000597 host exposure to environment containing infectious agent A host exposure to environment with infectious agent where the environment is a household that also has an infected host http://purl.obolibrary.org/obo/IDO_0000599 host living in endemic area http://purl.obolibrary.org/obo/IDO_0000597 host exposure to environment containing infectious agent A host exposure to environment with infectious agent where the environment is an area in which an infectious agent is endemic http://purl.obolibrary.org/obo/IDO_0000600 release of infectious human pathogen in laboratory http://purl.obolibrary.org/obo/IDO_0000597 host exposure to environment containing infectious agent A host exposure to environment with infectious agent where the exposure is accidental; the environment is a laboratory, and the infectious agent is infectious in humans. http://purl.obolibrary.org/obo/IDO_0000601 host coming into contact with vector of infectious agent http://purl.obolibrary.org/obo/IDO_0000597 host exposure to environment containing infectious agent A host exposure to environment with infectious agent where the environment contains an infectious agent vector. http://purl.obolibrary.org/obo/IDO_0000602 host exposure to substance that might have infectious agent http://purl.obolibrary.org/obo/IDO_0000597 host exposure to environment containing infectious agent A host exposure to environment with infectious agent where the environment contains a material entity that has been assessed to confer a risk of infection. http://purl.obolibrary.org/obo/IDO_0000603 process of establishing an infection http://purl.obolibrary.org/obo/BFO_0000015 process A process by which an infectious agent, established in a host, becomes part of an infection in the host. http://purl.obolibrary.org/obo/IDO_0000604 colonization of host http://purl.obolibrary.org/obo/IDO_0000625 establishment of localization in host An establishment of localization in host process in which an organism establishes itself in a host. http://purl.obolibrary.org/obo/IDO_0000605 _obsolete_biological object colony http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class A biological object or group of biological objects in close spatial proximity. http://purl.obolibrary.org/obo/IDO_0000606 establishment of a clinically abnormal colony http://purl.obolibrary.org/obo/IDO_0000604 colonization of host A colonization of host process that results in a clinically abnormal colony. http://purl.obolibrary.org/obo/IDO_0000607 production http://purl.obolibrary.org/obo/BFO_0000015 process A process in which an entity comes into being as a result of the process. http://purl.obolibrary.org/obo/IDO_0000608 replication http://purl.obolibrary.org/obo/IDO_0000607 production A production process in which a participant creates a copy of itself. http://purl.obolibrary.org/obo/IDO_0000609 colonization of human anterior nares http://purl.obolibrary.org/obo/IDO_0000650 colonization of human A colonization of human process in which the colonized site is the anterior nares. http://purl.obolibrary.org/obo/IDO_0000610 immunosuppression http://purl.obolibrary.org/obo/BFO_0000015 process A process that attenuates an immune response. http://purl.obolibrary.org/obo/IDO_0000611 physiologic immunosuppression http://purl.obolibrary.org/obo/IDO_0000610 immunosuppression An immunosuppression which unfolds as part of the natural self-regulation of an immune response. http://purl.obolibrary.org/obo/IDO_0000612 pathologic immunosuppression http://purl.obolibrary.org/obo/IDO_0000610 immunosuppression An immunosuppression process which arises as the result of a disorder. http://purl.obolibrary.org/obo/IDO_0000613 _obsolete_biological object http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class primitive http://purl.obolibrary.org/obo/IDO_0000614 _obsolete_replicating biological material entity http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class A biological material entity that is capable of replication. http://purl.obolibrary.org/obo/IDO_0000615 colony http://purl.obolibrary.org/obo/IDO_0000509 organism population An organism population persisting in a site it has colonized. http://purl.obolibrary.org/obo/IDO_0000616 infectious agent colony http://purl.obolibrary.org/obo/IDO_0000615 colony A colony whose members are infectious agents. http://purl.obolibrary.org/obo/IDO_0000617 immunodeficiency http://purl.obolibrary.org/obo/OGMS_0000045 disorder A disorder of an immune system component that results in defective functioning of the immune system. http://purl.obolibrary.org/obo/IDO_0000618 immunocompetence http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition that is the ability to mount a normal immune response. http://purl.obolibrary.org/obo/IDO_0000619 immunosuppressive disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition whose realization negatively regulates an immune response. http://purl.obolibrary.org/obo/IDO_0000622 disposition to form a non-parasitic colony http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to colonize an organism and participate in mutualism or commensalism with that organism. http://purl.obolibrary.org/obo/IDO_0000623 communicability http://purl.obolibrary.org/obo/IDO_0000452 infectious disposition An infectious disposition to be transmitted directly from one organism to another of the same Species by horizontal transmission. http://purl.obolibrary.org/obo/IDO_0000624 _obsolete_host range http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class A quality that inheres in an infection and is the likelihood that infectious agents part of the infection will spread to other hosts. http://purl.obolibrary.org/obo/IDO_0000625 establishment of localization in host http://purl.obolibrary.org/obo/GO_0051234 establishment of localization An establishment of localization process in which a material entity reaches a site in an organism in which it can survive, grow, multiply, or mature. http://purl.obolibrary.org/obo/IDO_0000626 appearance of disorder http://purl.obolibrary.org/obo/BFO_0000015 process A process by which a disorder comes into existence. http://purl.obolibrary.org/obo/IDO_0000627 acute infection http://purl.obolibrary.org/obo/IDO_0000504 infectious disorder An infectious disorder that is the physical basis for an unfolding acute infectious disease course. http://purl.obolibrary.org/obo/IDO_0000631 community-acquired infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection resulting from a transmission process that did not unfold in a health care facility. http://purl.obolibrary.org/obo/IDO_0000632 neurotoxin http://purl.obolibrary.org/obo/IDO_0000549 toxin A molecular entity with a toxin disposition, the realization of which damages or interferes with the function of nerve tissue. http://purl.obolibrary.org/obo/IDO_0000633 metatstatic infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection established as a result of spread from another infection in a non-adjacent location in the extended organism of the host. http://purl.obolibrary.org/obo/IDO_0000635 source of infection role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by a material entity in virtue of the fact that it contains a site from which an infectious agent is transmitted. http://purl.obolibrary.org/obo/IDO_0000636 sepsis http://purl.obolibrary.org/obo/BFO_0000015 process A process that is a systemic inflammatory response to infection. http://purl.obolibrary.org/obo/IDO_0000637 severe sepsis http://purl.obolibrary.org/obo/IDO_0000636 sepsis A sepsis that results in organ dysfunction, hypotension, or hypofusion of at least one organ. http://purl.obolibrary.org/obo/IDO_0000638 nursing-home acquired infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection resulting from a transmission process that unfolds in a nursing home. http://purl.obolibrary.org/obo/IDO_0000639 infectious human pathogen http://purl.obolibrary.org/obo/IDO_0000596 infectious agent An infectious agent with a capability to infect human hosts. http://purl.obolibrary.org/obo/IDO_0000640 acquired immunodeficiency http://purl.obolibrary.org/obo/IDO_0000617 immunodeficiency An immunodeficiency that is not caused by a genetic predisposition. http://purl.obolibrary.org/obo/IDO_0000642 simple infection http://purl.obolibrary.org/obo/IDO_0000586 infection An infection comprised of infectious organisms all of the same Species. http://purl.obolibrary.org/obo/IDO_0000643 re-emerging pathogen http://purl.obolibrary.org/obo/IDO_0000596 infectious agent An infectious agent whose infection incidence is increasing in a host population as a result of changes in the biology of the host or pathogen, or changes in their interactions. http://purl.obolibrary.org/obo/IDO_0000644 pregnancy-induced immunosuppression http://purl.obolibrary.org/obo/IDO_0000610 immunosuppression An immunosuppression induced by progesterone and other factors upregulated in pregnant women. http://purl.obolibrary.org/obo/IDO_0000645 candidiasis http://purl.obolibrary.org/obo/IDO_0000586 infection An infection that has as part organisms of the Genus Candida. http://purl.obolibrary.org/obo/IDO_0000646 trichomoniasis http://purl.obolibrary.org/obo/IDO_0000586 infection An infection that has as part organisms of the Species Trichomonas vaginalis. http://purl.obolibrary.org/obo/IDO_0000647 leptospirosis http://purl.obolibrary.org/obo/IDO_0000586 infection An infection that has as part organisms of the Genus Leptospira. http://purl.obolibrary.org/obo/IDO_0000648 Shigellosis http://purl.obolibrary.org/obo/IDO_0000586 infection An infection located in the bowel and that has as part organisms of the Genus Shigella. http://purl.obolibrary.org/obo/IDO_0000649 amebiasis http://purl.obolibrary.org/obo/IDO_0000586 infection An infection located in the colon and that has as part organisms of the Species Entamoeba histolytica http://purl.obolibrary.org/obo/IDO_0000650 colonization of human http://purl.obolibrary.org/obo/IDO_0000604 colonization of host A colonization of host process in which the host is of Species Homo sapiens. http://purl.obolibrary.org/obo/IDO_0000652 colonization of human perineum http://purl.obolibrary.org/obo/IDO_0000650 colonization of human A colonization of human process in which the colonized site is a perineum. http://purl.obolibrary.org/obo/IDO_0000653 reverse zoonosis http://purl.obolibrary.org/obo/IDO_0000436 infectious disease An infectious disease that has as its physical basis an infectious disorder composed of infectious agents that have a reverse zoonotic disposition. http://purl.obolibrary.org/obo/IDO_0000655 transmissibility disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to undergo a transmission process. http://purl.obolibrary.org/obo/IDO_0000656 horizontal pathogen transmission process http://purl.obolibrary.org/obo/TRANS_0000000 transmission process A pathogen transmission process in which a pathogen is transmitted from one host to another of the same Species, and the two hosts are not in a parent-child relationship. http://purl.obolibrary.org/obo/IDO_0000657 process that results in death http://purl.obolibrary.org/obo/BFO_0000015 process A process that results in death. http://purl.obolibrary.org/obo/IDO_0000658 host exposure to infectious agent http://purl.obolibrary.org/obo/BFO_0000015 process A process in which a potential host of an infectious agent is exposed to an infectious agent. http://purl.obolibrary.org/obo/IDO_0000659 susceptible organism http://purl.obolibrary.org/obo/OBI_0100026 organism An organism that is not infected with an infectious agent and lacks protective immunity to the infectious agent. http://purl.obolibrary.org/obo/IDO_0000662 life-sustaining process http://purl.obolibrary.org/obo/GO_0008150 biological_process A process which is necessary for the survival of an organism. http://purl.obolibrary.org/obo/IDO_0000663 negative regulation of life-sustaining process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that stops, prevents, or reduces the frequency, rate or extent of a life-sustaining process. http://purl.obolibrary.org/obo/IDO_0000665 source of infection http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity bearing a source of infection role. http://purl.obolibrary.org/obo/IDO_0000667 parasitic disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to participate in a process of symbiosis in which the bearer derives a growth, survival, or fitness advantage from symbiosis while the other symbiont's growth, survival, or fitness is reduced. http://purl.obolibrary.org/obo/IDO_0001002 transition to clinical abnormality http://purl.obolibrary.org/obo/BFO_0000015 process A process by which a part of an organism or something contained in an organism becomes clinically abnormal. http://purl.obolibrary.org/obo/OGMS_0000020 symptom http://purl.obolibrary.org/obo/BFO_0000001 entity A quality of a patient that is observed by the patient or a processual entity experienced by the patient, either of which is hypothesized by the patient to be a realization of a disease. http://purl.obolibrary.org/obo/OGMS_0000045 disorder http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease. http://purl.obolibrary.org/obo/BFO_0000148 zero-dimensional temporal region http://purl.obolibrary.org/obo/BFO_0000008 temporal region temporal instant. http://purl.obolibrary.org/obo/BFO_0000008 temporal region http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000011 spatiotemporal region http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000009 two-dimensional spatial region http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000018 zero-dimensional spatial region http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000026 one-dimensional spatial region http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000028 three-dimensional spatial region http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000038 one-dimensional temporal region http://purl.obolibrary.org/obo/BFO_0000008 temporal region http://purl.obolibrary.org/obo/BFO_0000182 history http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000034 function http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000024 fiat object http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000027 object aggregate http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000030 object http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000142 one-dimensional continuant fiat boundary http://purl.obolibrary.org/obo/BFO_0000140 continuant fiat boundary http://purl.obolibrary.org/obo/BFO_0000146 two-dimensional continuant fiat boundary http://purl.obolibrary.org/obo/BFO_0000140 continuant fiat boundary http://purl.obolibrary.org/obo/BFO_0000147 zero-dimensional continuant fiat boundary http://purl.obolibrary.org/obo/BFO_0000140 continuant fiat boundary http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/BFO_0000029 site http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/NCBITaxon_10239 Viruses http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/NCBITaxon_2157 Archaea http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/IDO_0000000 _obsolete_process http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000001 _obsolete_role http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000002 _obsolete_quality http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000003 _obsolete_object http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class 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http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000211 _obsolete_quality of pathogen http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000213 _obsolete_resistance http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000214 _obsolete_refractoriness http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000215 _obsolete_quality of host population http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000216 _obsolete_herd immunity http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000217 _obsolete_quality of infectious disease http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000218 _obsolete_case of infectious disease http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000220 _obsolete_infectivity period http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000222 _obsolete_infectious disease course http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000223 _obsolete_host recovery period http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000224 _obsolete_intrinsic incubation period http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000225 _obsolete_extrinsic incubation period http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000228 _obsolete_pathogen outbreak http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000229 _obsolete_oral-fecal transmission http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000230 _obsolete_vertical transmission http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000231 _obsolete_horizontal transmission http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000232 _obsolete_pathogen life cycle stage http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000233 _obsolete_infectious disease progression stage http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000300 _obsolete_progression rate http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000301 _obsolete_rapid progression http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000302 _obsolete_long-term non-progression http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000303 _obsolete_highly exposed persistently seronegative http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/IDO_0000305 _obsolete_co-infected http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/BFO_0000001 entity http://www.geneontology.org/formats/oboInOwl#ObsoleteClass Obsolete Class http://purl.obolibrary.org/obo/RO_0002234 has output http://purl.obolibrary.org/obo/RO_0000057 has participant produces p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p. http://purl.obolibrary.org/obo/RO_0000079 function of http://purl.obolibrary.org/obo/RO_0000052 inheres in is function of a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000080 quality of http://purl.obolibrary.org/obo/RO_0000052 inheres in quality_of a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000085 has function http://purl.obolibrary.org/obo/RO_0000053 bearer of has_function a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000086 has quality http://purl.obolibrary.org/obo/RO_0000053 bearer of has_quality a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002350 member of http://purl.obolibrary.org/obo/BFO_0000050 part of member part of is member of is a mereological relation between a item and a collection. http://purl.obolibrary.org/obo/RO_0000087 has role http://purl.obolibrary.org/obo/RO_0000053 bearer of has_role a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000081 role of http://purl.obolibrary.org/obo/RO_0000052 inheres in role_of a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002351 has member http://purl.obolibrary.org/obo/BFO_0000051 has part has member is a mereological relation between a collection and an item. http://purl.obolibrary.org/obo/RO_0000091 has disposition http://purl.obolibrary.org/obo/RO_0000053 bearer of a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002212 negatively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates x negatively regulates y if and only if the progression of x reduces the frequency, rate or extent of y http://purl.obolibrary.org/obo/RO_0002213 positively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates x positively regulates y if and only if the progression of x increases the frequency, rate or extent of y http://purl.obolibrary.org/obo/RO_0000092 disposition of http://purl.obolibrary.org/obo/RO_0000052 inheres in http://purl.obolibrary.org/obo/RO_0002297 results in formation of http://purl.obolibrary.org/obo/IDO_0000660 results_in http://purl.obolibrary.org/obo/RO_0000052 inheres in inheres_in a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000053 bearer of is bearer of a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000056 participates in participates_in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000057 has participant has_participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0001000 derives from derives_from a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0001001 derives into derives_into a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0001015 location of location_of a relation between two independent continuants, the location and the target, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0002000 2D boundary of is boundary of a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0002002 has 2D boundary has_2D_boundary a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0001025 located in located_in a relation between two independent continuants, the target and the location, in which the target is entirely within the location http://purl.obolibrary.org/obo/BFO_0000051 has part has_part a core relation that holds between a whole and its part http://purl.obolibrary.org/obo/BFO_0000050 part of part_of a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/BFO_0000066 occurs in unfolds_in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0002215 capable of has function realized in A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. http://purl.obolibrary.org/obo/BFO_0000067 contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0000058 is concretized as A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants. http://purl.obolibrary.org/obo/RO_0000059 concretizes A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant. http://purl.obolibrary.org/obo/RO_0002211 regulates x regulates y if and only if the x is the realization of a function to exert an effect on the frequency, rate or extent of y http://purl.obolibrary.org/obo/BFO_0000054 realized in realized_in http://purl.obolibrary.org/obo/BFO_0000062 preceded by preceded_by http://purl.obolibrary.org/obo/BFO_0000055 realizes http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/IDO_0000664 has_material_basis_in http://purl.obolibrary.org/obo/IDO_0000660 results_in