Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/OAE_0000027 musculoskeletal or connective tissue AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event musculoskeletal and connective tissue disorder AE an adverse event that has an outcome of abnormal sign in a musculoskeletal or connective tissue. http://purl.obolibrary.org/obo/OAE_0000063 systematic AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event systematic adverse event an adverse event that occurs systematically throughout the systemic circulation. This is different from local adverse event that is limited or a certain location. http://purl.obolibrary.org/obo/OAE_0000162 sensory neuropathy AE http://purl.obolibrary.org/obo/OAE_0000418 neuropathy AE sensory neuropathy AE a peripheral neuropathy AE which has an outcome of sensory neuropathy that involves damage to nerves of the peripheral nervous system. http://purl.obolibrary.org/obo/OAE_0000183 circulatory shock AE http://purl.obolibrary.org/obo/OAE_0000493 cardiovascular AE shock a cardiovascular disorder AE that is a result of insufficient blood flow throughout the body. Shock often accompanies severe injury or illness. http://purl.obolibrary.org/obo/OAE_0000199 hair, skin or nail AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event hair, skin, and nail AE an adverse event that occurs in hair, skin, or nail. http://purl.obolibrary.org/obo/OAE_0000287 aplastic anaemia AE http://purl.obolibrary.org/obo/OAE_0000550 anemia AE aplastic anemia Aplastic anaemia AE is an anemia AE that occurs when the bone marrow, and the blood stem cells that reside there are damaged. This causes a deficiency of all three blood cell types (pancytopenia): red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia). http://purl.obolibrary.org/obo/OAE_0000310 dyspnea AE http://purl.obolibrary.org/obo/OAE_0000571 abnormal respiration AE dyspnoea AE dyspnoea AE is an abnormal respiration AE debilitating symptom that is the experience of unpleasant or uncomfortable respiratory sensations, shortness of breath, air hunger http://purl.obolibrary.org/obo/OAE_0000316 conduction system disorder AE http://purl.obolibrary.org/obo/OAE_0000084 cardiac disorder AE conduction disorder AE a cardiac disorder AE of the electrical conduction system that controls the heart rate, generates and conducts electrical impulses throughout the muscle of the heart, stimulating the heart to contract and pump blood. http://purl.obolibrary.org/obo/OAE_0000350 rhinitis AE http://purl.obolibrary.org/obo/OAE_0000564 respiratory system inflammation AE runny nose rhinitis AE is a respiratory system inflammation characterized by runny nose,irritation and inflammation of some internal areas of the nose http://purl.obolibrary.org/obo/OAE_0000361 fever AE http://purl.obolibrary.org/obo/OAE_0000624 abnormal body temperature AE pyrexia AE an abnormal body temperature AE which has an outcome of fever http://purl.obolibrary.org/obo/OAE_0000363 infection AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event infectious adverse event an adverse event that has an outcome of a pathogen infection, i.e., an infection caused by a pathogen such as a virus, bacterium, or parasite. http://purl.obolibrary.org/obo/OAE_0000373 pruritus AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE pruritus generalised AE a skin adverse event that has an outcome of pruritus http://purl.obolibrary.org/obo/OAE_0000375 myalgia AE http://purl.obolibrary.org/obo/OAE_0000374 pain AE muscle pain AE a pain AE that has outcome of myalgia. Myalgia means "muscle pain" and is a symptom of many diseases and disorders. http://purl.obolibrary.org/obo/OAE_0000376 urticaria AE http://purl.obolibrary.org/obo/OAE_0000362 rash AE hives Urticaria AE is a rash AE notable for dark red, raised, itchy bumps. http://purl.obolibrary.org/obo/OAE_0000379 leukocyte cell number increased AE http://purl.obolibrary.org/obo/OAE_0001673 leukocyte cell number abnormal AE white blood cell count increased AE a leukocyte cell number abnormal AE that has an outcome of greater than normal number of leukocytes, or nucleated cells of the myeloid or lymphoid lineages, found in blood or other tissue http://purl.obolibrary.org/obo/OAE_0000391 somnolence AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE drowsiness a behavior and neurological AE that has an outcome of somnolence http://purl.obolibrary.org/obo/OAE_0000392 paresthesia AE http://purl.obolibrary.org/obo/OAE_0000162 sensory neuropathy AE paraesthesia AE a sensory neuropathy AE that shows a sensation of tingling, pricking, or numbness of a person's skin with no apparent long-term physical effect. http://purl.obolibrary.org/obo/OAE_0000396 anorexia AE http://purl.obolibrary.org/obo/OAE_0000574 gustatory system AE decreased appetite AE a gustatory system AE which demonstrates a decreased sensation of appetite. http://purl.obolibrary.org/obo/OAE_0000398 cough AE http://purl.obolibrary.org/obo/OAE_0000571 abnormal respiration AE coughing AE an abnormal respiration AE that shows a sudden and often repetitively occurring reflex to keep the throat and airways clear http://purl.obolibrary.org/obo/OAE_0000403 hypertension AE http://purl.obolibrary.org/obo/OAE_0000381 abnormal blood pressure AE blood pressure increased an abnormal blood pressure AE that has an outcome of sustained high blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states http://purl.obolibrary.org/obo/OAE_0000416 gastrointestinal hemorrhage AE http://purl.obolibrary.org/obo/OAE_0000427 hemorrhage AE gastrointestinal haemorrhage AE a hemorrhage AE that has an outcome of gastrointestinal hemorrhage http://purl.obolibrary.org/obo/OAE_0000423 skin discoloration AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE skin discolouration AE skin discoloration AE is a skin adverse event that results in change in color of skin or mucus membranes http://purl.obolibrary.org/obo/OAE_0000427 hemorrhage AE http://purl.obolibrary.org/obo/OAE_0000493 cardiovascular AE haemorrhage AE a cardiovascular disorder AE that has an outcome of hemorrhage http://purl.obolibrary.org/obo/OAE_0000436 hepatobiliary or pancreatic AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event liver, biliary, and pancreatic disorder AE an adverse event that occurs in liver, biliary, and pancreatic areas. http://purl.obolibrary.org/obo/OAE_0000443 eye AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event eye disorder AE an AE that occurs in eye. http://purl.obolibrary.org/obo/OAE_0000461 cardiac arrest http://purl.obolibrary.org/obo/OAE_0000084 cardiac disorder AE heart arrest AE a cardiac disorder AE that has an outcome of heartarrest, the abrupt cessation of normal circulation of the blood due to failure of the heart to contract effectively during systole. http://purl.obolibrary.org/obo/OAE_0000465 ear AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event ear disorder AE an AE that occurs in ear. http://purl.obolibrary.org/obo/OAE_0000466 viral infection AE http://purl.obolibrary.org/obo/OAE_0000363 infection AE viral infection an infection AE that results in detrimental colonization of a host organism by virus http://purl.obolibrary.org/obo/OAE_0000468 jaundice AE http://purl.obolibrary.org/obo/OAE_0001135 liver AE icterus AE a liver/biliary system AE which has an outcome of jaundice, which is the clinical manifestation of hyperbilirubinemia, with deposition of bile pigments in the skin, resulting in yellowish staining of the skin and mucous membranes http://purl.obolibrary.org/obo/OAE_0000476 immune system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event immune system disorder AE an AE that occurs in immune system. http://purl.obolibrary.org/obo/OAE_0000493 cardiovascular AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event cardiovascular disorder AE an AE that occurs in cardiovascular system. http://purl.obolibrary.org/obo/OAE_0000505 dry mouth AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE xerostomia a digestive system AE which has an outcome of dry mouth, which is dryness of the mouth resulting from reduced salivary secretion http://purl.obolibrary.org/obo/OAE_0000508 epistaxis AE http://purl.obolibrary.org/obo/OAE_0000427 hemorrhage AE nosebleed a hemorrhage AE that has an outcome of epistaxis http://purl.obolibrary.org/obo/OAE_0000518 bone AE http://purl.obolibrary.org/obo/OAE_0000027 musculoskeletal or connective tissue AE bone disorder a musculoskeletal system AE that occurs in the bone http://purl.obolibrary.org/obo/OAE_0000544 abnormal gait AE http://purl.obolibrary.org/obo/OAE_0000581 movement disorder AE gait disturbance AE a movement disorder AE that has an outcome of unusual or distinctive way of walking http://purl.obolibrary.org/obo/OAE_0000550 anemia AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE anaemia AE a hematopoietic system AE which has an outcome of anemia, which is less than normal levels of red blood cells and/or hemoglobin within red blood cells, or volume of packed red blood cells in the bloodstream, resulting in insufficient oxygenation of tissues and organs http://purl.obolibrary.org/obo/OAE_0000551 hypotension AE http://purl.obolibrary.org/obo/OAE_0000381 abnormal blood pressure AE blood pressure decreased, low blood pressure an abnormal blood pressure AE that has an outcome of sustained low blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states http://purl.obolibrary.org/obo/OAE_0000556 edema AE http://purl.obolibrary.org/obo/OAE_0000546 abnormal fluid regulation AE oedema, swelling, dropsy an abnormal fluid regulation AE which has an outcome of edema, which is an accumulation of an excessive amount of watery fluid in cells or intercellular tissues http://purl.obolibrary.org/obo/OAE_0000568 allergy AE http://purl.obolibrary.org/obo/OAE_0000584 hypersensitivity AE anaphylactic reaction AE a hypersensitivity AE which results in an allergic response showing a marked increase in reactivity to an antigen upon subsequent exposure. http://purl.obolibrary.org/obo/OAE_0000570 nervous system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event nervous system disorder AE an AE that occurs in nervous system. http://purl.obolibrary.org/obo/OAE_0000572 apnea AE http://purl.obolibrary.org/obo/OAE_0000571 abnormal respiration AE MedDRA: 10002974 is for "apnoea"; MedDRA: 10002972 is for "apnea". an abnormal respiration AE which has an outcome of apnea, temporary cessation of breathing; sometimes episodic http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event disruptive behavioral disorder AE an adverse event that has an outcome of an abnormal behavior and neurological phenotype. http://purl.obolibrary.org/obo/OAE_0000584 hypersensitivity AE http://purl.obolibrary.org/obo/OAE_0000476 immune system AE hypersensitivity reaction AE Hypersensitivity AE is a immune system AE that is a set of undesirable reactions produced by the normal immune system, including allergies and autoimmunity. These reactions may be damaging, uncomfortable, or occasionally fatal. http://purl.obolibrary.org/obo/OAE_0000587 hypoventilation AE http://purl.obolibrary.org/obo/OAE_0000571 abnormal respiration AE respiratory depression AE an abnormal respiration AE which has an outcome of hypoventilation, i.e., reduced alveolar ventilation relative to metabolic carbon dioxide production; results in alveolar carbon dioxide pressure increasing above normal http://purl.obolibrary.org/obo/OAE_0000590 increased heart rate AE http://purl.obolibrary.org/obo/OAE_0000660 arrhythmia AE tachycardia an arrhythmia AE that has an outcome of greater than average resting heart beats per minute, usually measured by the number of times the heart ventricles contract per unit of time, usually per minute http://purl.obolibrary.org/obo/OAE_0000604 urinary incontinence AE http://purl.obolibrary.org/obo/OAE_0000622 urinary system AE MedDRA: 10046543 a urinary system AE that has an outcome of the symptom of urinary incontinence, which is the inability to control the urinary excretory functions. http://purl.obolibrary.org/obo/OAE_0000616 diarrhea AE http://purl.obolibrary.org/obo/OAE_0000603 abnormal defecation AE diarrhoea AE an abnormal defecation AE that has an outcome of diarrhea, which is abnormally frequent discharge of semi-solid or fluid fecal matter from the bowel http://purl.obolibrary.org/obo/OAE_0000619 hematuria AE http://purl.obolibrary.org/obo/OAE_0000622 urinary system AE haematuria AE a urinary system AE that results in the presence of blood in the urine http://purl.obolibrary.org/obo/OAE_0000628 investigation result abnormal AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event laboratory test abnormal an adverse event that is indicated by an abnormal result of an investigation that uses some laboratory equipment, device, or medical technology. http://purl.obolibrary.org/obo/OAE_0000645 erythema AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE reddish skin Erythema AE is a skin adverse event that showns redness of the skin caused by hyperemia of the capillaries in the lower layers of the skin. http://purl.obolibrary.org/obo/OAE_0000660 arrhythmia AE http://purl.obolibrary.org/obo/OAE_0000084 cardiac disorder AE cardiac arrhythmia AE a cardiac disorder AE which has an outcome of abnormal heart rhythm http://purl.obolibrary.org/obo/OAE_0000688 stomach discomfort AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE stomach upset AE a digestive system AE which has an outcome of stomach discomfort http://purl.obolibrary.org/obo/OAE_0000691 skin ulceration AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE skin ulcer AE a skin AE that shows a result of skin ulcer, i.e., a sore on the skin or a mucous membrane, accompanied by the disintegration of tissue. Ulcers can result in complete loss of the epidermis and often portions of the dermis and even subcutaneous fat. http://purl.obolibrary.org/obo/OAE_0000752 bone marrow depression AE http://purl.obolibrary.org/obo/OAE_0000753 bone marrow disorder AE hypocellular bone marrow a bone marrow disorder AE that has an outcome of an abnormal condition in which the bone marrow is unable to produce normal amounts of red blood cells, white blood cells and platelets http://purl.obolibrary.org/obo/OAE_0000779 cardiac failure AE http://purl.obolibrary.org/obo/OAE_0000084 cardiac disorder AE heart failure a cardiovascular disorder AE that results in the inability of the heart to provide sufficient pump action to distribute blood flow to meet the needs of the body http://purl.obolibrary.org/obo/OAE_0000801 cerebral hemorrhage AE http://purl.obolibrary.org/obo/OAE_0001551 brain AE cerebral haemorrhage AE a brain disorder AE with the outcome of hemorrhage or blood in the brain http://purl.obolibrary.org/obo/OAE_0000902 dysuria AE http://purl.obolibrary.org/obo/OAE_0000622 urinary system AE urination disorders AE Dysuria AE is an urinary system AE that results in painful urination http://purl.obolibrary.org/obo/OAE_0000937 eyelid edema AE http://purl.obolibrary.org/obo/OAE_0004244 eye edema AE eyelid oedema AE an eye edema AE that has an outcome of swelling in either or both the lower and upper eyelids, due to fluid buildup or inflammation in the delicate tissues surrounding the eye. http://purl.obolibrary.org/obo/OAE_0001004 hematochezia AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE haematochezia AE a digestive system AE that has an outcome of the passage of bloody stools http://purl.obolibrary.org/obo/OAE_0001012 hemolytic uremic syndrome AE http://purl.obolibrary.org/obo/OAE_0000364 syndrome AE haemolytic uraemic syndrome AE a hematopoietic system AE that has an outcome of hemolytic anemia, acute kidney failure and a low platelet count http://purl.obolibrary.org/obo/OAE_0001124 leukemoid reaction AE http://purl.obolibrary.org/obo/OAE_0000476 immune system AE leukaemoid reaction AE Immune system disorder AE that results in an increase in white blood cell count as a result of stress or infection http://purl.obolibrary.org/obo/OAE_0001135 liver AE http://purl.obolibrary.org/obo/OAE_0000436 hepatobiliary or pancreatic AE liver disorder Liver/biliary system AE that results in the disease of the liver http://purl.obolibrary.org/obo/OAE_0001166 melena AE http://purl.obolibrary.org/obo/OAE_0000603 abnormal defecation AE melaena AE Abnormal defecation AE that results in black feces associated with gastrointestinal hemorrhage http://purl.obolibrary.org/obo/OAE_0001215 neurotoxicity AE http://purl.obolibrary.org/obo/OAE_0000418 neuropathy AE toxic neuropathy AE a nervous system AE that alters the normal activity of the nervous system due to exposure to neurotoxins (which can be natural or artificial toxic substances), and causes damage to nervous tissue http://purl.obolibrary.org/obo/OAE_0001365 acute kidney injury AE http://purl.obolibrary.org/obo/OAE_0000328 kidney AE renal failure acute AE a kidney disorder AE that results in the rapid loss or decline of kidney function http://purl.obolibrary.org/obo/OAE_0001370 respiratory acidosis AE http://purl.obolibrary.org/obo/OAE_0000378 respiratory system AE respiratory failure AE a respiratory system AE that has an outcome of a condition where lungs cannot remove all the carbon dioxide the body produces, makes body fluid too acidic http://purl.obolibrary.org/obo/OAE_0001430 gastric hemorrhage AE http://purl.obolibrary.org/obo/OAE_0000416 gastrointestinal hemorrhage AE gastric haemorrhage AE A gastrointestinal hemorrhage AE that has an outcome of the bleeding in the stomach http://purl.obolibrary.org/obo/OAE_0001443 tachypnea AE http://purl.obolibrary.org/obo/OAE_0000571 abnormal respiration AE tachypnoea AE an abnormal repiration AE that shows an outcome of tachypnoea (i.e., abnormally rapid breathing or respiration) http://purl.obolibrary.org/obo/OAE_0001484 upper gastrointestinal hemorrhage AE http://purl.obolibrary.org/obo/OAE_0000416 gastrointestinal hemorrhage AE upper gastrointestinal haemorrhage AE a gastrointestinal hemorrhage AE that has an outcome of bleeding in the upper gastrointestinal tract http://purl.obolibrary.org/obo/OAE_0001509 vision blurred AE http://purl.obolibrary.org/obo/OAE_0000578 abnormal vision AE blurred vision AE an abnormal vision AE that results in unclear vision http://purl.obolibrary.org/obo/OAE_0001551 brain AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event brain disorder AE an adverse event that occurs in brain. http://purl.obolibrary.org/obo/OAE_0001587 urinary system investigation result abnormal AE http://purl.obolibrary.org/obo/OAE_0000628 investigation result abnormal AE renal system investigation result abnormal AE an investigation result abnormal AE that involves the renal and urinary tract and urinalyses http://purl.obolibrary.org/obo/OAE_0001664 hematology investigation result abnormal AE http://purl.obolibrary.org/obo/OAE_0000628 investigation result abnormal AE haematology investigation abnormal AE an investigation result abnormal AE that is characterized by an abnormal result of a hematology investigation http://purl.obolibrary.org/obo/OAE_0001750 severity of adverse event http://purl.obolibrary.org/obo/PATO_0001236 process quality AE severity a process quality that represents the level of severity of an adverse event. http://purl.obolibrary.org/obo/OAE_0001797 psychiatric disorder AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE mental disorder AE a behavior and neurological AE that has an outcome of a mental illness or psychiatiric disorder. The mental illness is a mental or behavioral pattern or anomaly that causes either suffering or an impaired ability to function in ordinary life (disability), and which is not developmentally or socially normative. http://purl.obolibrary.org/obo/OAE_0001836 AE severity G1 http://purl.obolibrary.org/obo/OAE_0001750 severity of adverse event AE severity Grade 1 a severity of AE that shows asymptomatic, or involves mild or minor symptoms, or is of marginal clinical relevance, or consists of clinical or diagnostic observations alone, or where intervention is not indicated, or where only non-prescription intervention is indicated. http://purl.obolibrary.org/obo/OAE_0001837 AE severity G2 http://purl.obolibrary.org/obo/OAE_0001750 severity of adverse event AE severity Grade 2 a severity of AE for which only minimal, local, or noninvasive intervention (e.g. packing, cautery) is indicated, or that limits instrumental activities of daily living (ADLs, e.g., shopping, laundry, transportation, or ability to conduct finances). http://purl.obolibrary.org/obo/OAE_0001838 AE severity G3 http://purl.obolibrary.org/obo/OAE_0001750 severity of adverse event AE severity Grade 3 a severity of AE that shows an outcome which is medically significant but not life-threatening; or for which inpatient care or prolongation of hospitalization are indicated; or that is an important medical event that does not result in hospitalization, but may jeopardize the patient or may require intervention either to prevent hospitalization, to prevent the AE from becoming life-threatening or causing death; or that is disabling; or that results in persistent or significant disability, incapacity, or limitation of self care activities of daily living (ADLs, getting in and out of bed, dressing, eating, getting around inside, bathing, or using the toilet). http://purl.obolibrary.org/obo/OAE_0001839 AE severity G4 http://purl.obolibrary.org/obo/OAE_0001750 severity of adverse event AE severity Grade 4 a severity of AE that has life-threatening consequences, for which urgent intervention is indicated, that puts the patient is at risk of death at the time of the event if immediate intervention is not undertaken, or that causes blindness or deafness (need to decide if unilateral or bilateral). http://purl.obolibrary.org/obo/OAE_0001840 AE severity G5 http://purl.obolibrary.org/obo/OAE_0001750 severity of adverse event AE severity Grade 5 a severity of AE that results in death. http://purl.obolibrary.org/obo/OAE_0001845 gastric disorder AE http://purl.obolibrary.org/obo/OAE_0000455 gastrointestinal disorder AE stomach disorder AE a gastrointestinal disorder AE that shows a problem with the stomach, ranging from indigestion and heartburn to peptic ulcers and GERD. http://purl.obolibrary.org/obo/OAE_0001899 hypoactive sexual desire disorder AE http://purl.obolibrary.org/obo/OAE_0001130 libido disorder AE hyposexuality AE Hypoactive sexual desire disorder AE is a libido disorder AE that is considered a sexual dysfunction and is characterized as a lack or absence of sexual fantasies and desire for sexual activity, as judged by a clinician. http://purl.obolibrary.org/obo/OAE_0001919 eructation AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE ructus AE Eructation AE is a digestive system AE that is the release of gas from the digestive tract (mainly esophagus and stomach) through the mouth. It is usually accompanied with a typical sound and, at times, an odor. http://purl.obolibrary.org/obo/OAE_0001922 stomach ache AE http://purl.obolibrary.org/obo/OAE_0000402 abdominal pain AE stomachache AE Stomachache AE is a pain AE that the pain in or near your stomach. It is a common symptom associated with transient disorders or serious disease. http://purl.obolibrary.org/obo/OAE_0001927 interstitial nephritis AE http://purl.obolibrary.org/obo/OAE_0000557 inflammation AE tubulointerstitial nephritis AE Interstitial nephritis AE is an inflammation AE that is a form of nephritis affecting the interstitium of the kidneys surrounding the tubules. This disease can be either acute, meaning it occurs suddenly, or chronic, meaning it is ongoing and eventually ends in kidney failure. http://purl.obolibrary.org/obo/OAE_0001990 herpes simplex AE http://purl.obolibrary.org/obo/OAE_0003233 herpes viral infection AE herpes catarrhalis AE a herpes viral infection AE tha is caused by both Herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). http://purl.obolibrary.org/obo/OAE_0001995 unconsciousness AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE loss of consciousness AE Unconsciousness AE is a sensory capability AE that is a state which occurs when the ability to maintain a awareness of self and environment is lost, it involves a complete or near-complete lack of responsiveness to people and other environmental stimuli. http://purl.obolibrary.org/obo/OAE_0001998 miosis AE http://purl.obolibrary.org/obo/OAE_0000443 eye AE myosis AE Miosis AE is an eye AE that is a term with various definitions, which generally include constriction of the pupil. http://purl.obolibrary.org/obo/OAE_0002050 hyperesthesia AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE hyperaesthesia AE a sensory capability AE that has an outcome of hyperaesthesia, meaning unusual or pathological sensitivity of the skin or of a particular sense http://purl.obolibrary.org/obo/OAE_0002095 fecal incontinence AE http://purl.obolibrary.org/obo/OAE_0000603 abnormal defecation AE faecal incontinence AE an abnormal defecation AE that has an outcome of fecal incontinence, the accidental passing of solid or liquid stool or mucus from the rectum http://purl.obolibrary.org/obo/OAE_0002112 epigastric discomfort AE http://purl.obolibrary.org/obo/OAE_0000081 discomfort AE upper Abdominal discomfort AE Epigastric discomfort is a discomfort AE that shows discomfort in the upper central region of the abdomen. http://purl.obolibrary.org/obo/OAE_0002299 obviously decreased blood pressure AE http://purl.obolibrary.org/obo/OAE_0000551 hypotension AE significantly decreased blood pressure AE Obviously decreased blood pressure AE is a hypotension AE that shows obviously sustained low blood pressure at a level that is likely to result in cardiovascular disease and/or other pathological states. http://purl.obolibrary.org/obo/OAE_0002330 proarrhythmic effect AE http://purl.obolibrary.org/obo/OAE_0000660 arrhythmia AE arhythmia auxo-action AE Proarrhythmic effect AE is an arrhythmia AE that is a new or more frequent occurrence of pre-existing arrhythmias, paradoxically precipitated by antiarrhythmic therapy, which means it is a side effect associated with the administration of some existing antiarrhythmic drugs, as well as drugs for other indications. In other words, it is a tendency of antiarrhythmic drugs to facilitate emergence of new arrhythmias. http://purl.obolibrary.org/obo/OAE_0002439 menstruation irregular AE http://purl.obolibrary.org/obo/OAE_0002421 menstrual disorder AE irregular menstruation AE Menstruation irregular AE is a endocrine system AE that is an abnormal variation in length of menstrual cycles in a female. http://purl.obolibrary.org/obo/OAE_0002485 cryptorchidism AE http://purl.obolibrary.org/obo/OAE_0000083 male reproductive system AE undescended testis cryptorchidism AE is a male reproductive system AE which results in the absence of one or both testes from the scrotum. http://purl.obolibrary.org/obo/OAE_0002552 epileptic seizure AE http://purl.obolibrary.org/obo/OAE_0000579 seizure AE epilepsy a seizure AE that shows a brief episode of signs and/or symptoms due to abnormal excessive or synchronous neuronal activity in the brain. http://purl.obolibrary.org/obo/OAE_0002626 injury or procedural complication AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event injury and procedural complication AE an adverse event that shows a result of injury or procedural complication. http://purl.obolibrary.org/obo/OAE_0003245 dysstasia AE http://purl.obolibrary.org/obo/OAE_0003243 coordination and balance disorder AE dystasia AE a coordination and balance disorder AE that has difficulty in standing http://purl.obolibrary.org/obo/OAE_0003247 gastrorrhexis AE http://purl.obolibrary.org/obo/OAE_0003248 rupture AE stomach rupture a gastric disorder AE that shows an rupture in the stomach http://purl.obolibrary.org/obo/OAE_0004214 acute gastric mucosal lesion AE http://purl.obolibrary.org/obo/OAE_0001845 gastric disorder AE AGML AE a gastric disorder AE that shows the body under stress, causing acute erosion, bleeding and ulcers, stomach or duodenal mucosa damage collectively. The main clinical manifestations include upper gastrointestinal bleeding and a small perforation. http://purl.obolibrary.org/obo/OAE_0004221 lumbago AE http://purl.obolibrary.org/obo/OAE_0000414 back pain AE low back pain AE a back pain AE that occurs at the low back http://purl.obolibrary.org/obo/OAE_0004233 percussion procedure http://purl.obolibrary.org/obo/OAE_0004232 physical examination percussion test a physical test by which a surface is tapped to determine the underlying structure, and is used in clinical examinations to assess the condition of the thorax or abdomen. http://purl.obolibrary.org/obo/OAE_0004234 cylindruria AE http://purl.obolibrary.org/obo/OAE_0000694 urine analysis result abnormal AE urinary casts present AE a urine analysis result abnomal AE that shows cylindrical structures produced by the kidney and present in the urine. http://purl.obolibrary.org/obo/OAE_0004262 feces pale AE http://purl.obolibrary.org/obo/OAE_0000532 abnormal stool AE faeces pale AE an abnormal stool AE that shows pale or clay-colored stool. http://purl.obolibrary.org/obo/OAE_0004280 hypomenorrhea AE http://purl.obolibrary.org/obo/OAE_0002421 menstrual disorder AE hypomenorrhoea AE a menstrual disorder AE that shows an extremely light menstrual blood flow http://purl.obolibrary.org/obo/OAE_0004285 low estrogen level AE http://purl.obolibrary.org/obo/OAE_0001647 endocrine investigation result abnormal AE hypoestrogenism AE an endocrine investigation result abnormal AE that is characterized by a lower than normal level of estrogen, the primary sex hormone in women http://purl.obolibrary.org/obo/OAE_0004288 pure red cell aplasia AE http://purl.obolibrary.org/obo/OAE_0000287 aplastic anaemia AE red-cell aplasia, pure an aplastic anemia AE that results in the suppression of erythropoiesis with little or no abnormality of leukocyte or platelet production. http://purl.obolibrary.org/obo/OAE_0004292 erythema nodosum AE http://purl.obolibrary.org/obo/OAE_0000645 erythema AE erythemanodosum AE an erythema AE that showns an erythematous eruption characterized by inflammatory nodules that are usually tender, multiple, and bilateral. Such a symptom is commonly associated with drug reactions or infection. http://purl.obolibrary.org/obo/OAE_0004298 premature ovarian failure AE http://purl.obolibrary.org/obo/OAE_0000082 female reproductive system AE primary ovarian insufficiency AE a female reproductive system AE that occurs at the ovaries where ovaries do not produce estrogen despite high levels of circulating gonadotropins in women under 40. http://purl.obolibrary.org/obo/OAE_0004349 asphyxia AE http://purl.obolibrary.org/obo/OAE_0000571 abnormal respiration AE asphyxiation AE An abnormal respiration AE that shows a severely deficient supply of oxygen to the body that arises from abnormal breathing. http://purl.obolibrary.org/obo/OBI_0000576 scattered molecular aggregate http://purl.obolibrary.org/obo/BFO_0000027 object aggregate Collective A scattered molecular aggregate is a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates http://purl.obolibrary.org/obo/OAE_0000001 adverse event http://purl.obolibrary.org/obo/OGMS_0000061 pathological bodily process adverse reaction a pathological bodily process that occurs after a medical intervention. An adverse event is likely caused by the medical intervention; however, such a causal association is not required to be an adverse event. http://purl.obolibrary.org/obo/CHEBI_10274 alpha-Elemolic acid http://purl.obolibrary.org/obo/CHEBI_36615 triterpenoid A triterpenoid that has formula C30H48O3. http://purl.obolibrary.org/obo/CHEBI_10352 beta-amyrin http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol A pentacyclic triterpenoid that is oleanane substituted at the 3beta-position by a hydroxy group and containing a double bond between positions 12 and 13. It is one of the most commonly occurring triterpenoids in higher plants. http://purl.obolibrary.org/obo/CHEBI_15341 beta-D-glucosiduronic acid http://purl.obolibrary.org/obo/CHEBI_24302 glucosiduronic acid A glucosiduronic acid resulting from the formal condensation of any substance with beta-D-glucuronic acid to form a glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_15756 hexadecanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain, sixteen-carbon, saturated long-chain fatty acid. http://purl.obolibrary.org/obo/CHEBI_15903 beta-D-glucose http://purl.obolibrary.org/obo/CHEBI_4167 D-glucopyranose D-Glucopyranose with beta configuration at the anomeric centre. http://purl.obolibrary.org/obo/CHEBI_16196 oleic acid http://purl.obolibrary.org/obo/CHEBI_36021 octadec-9-enoic acid An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry. http://purl.obolibrary.org/obo/CHEBI_17579 beta-carotene http://purl.obolibrary.org/obo/CHEBI_35163 cyclic carotene A cyclic carotene obtained by dimerisation of all-trans-retinol. A strongly-coloured red-orange pigment abundant in plants and fruit and the most active and important provitamin A carotenoid. http://purl.obolibrary.org/obo/CHEBI_22950 butan-4-olide http://purl.obolibrary.org/obo/CHEBI_47016 tetrahydrofuranone Any gamma-lactone having the lactone moiety derived from 4-hydroxybutanoic acid. http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). http://purl.obolibrary.org/obo/CHEBI_24129 furans http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Compounds containing at least one furan ring. http://purl.obolibrary.org/obo/CHEBI_24302 glucosiduronic acid http://purl.obolibrary.org/obo/CHEBI_35314 glycosiduronic acid Any substance produced by linking glucuronic acid to another substance via a glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_24654 hydroxy fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid carrying one or more hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_24689 hydroxycinnamic acid http://purl.obolibrary.org/obo/CHEBI_23252 cinnamic acids Any member of the class of cinnamic acids carrying one or more hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_24921 isoquinoline alkaloid http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid Any alkaloid that has a structure based on an isoquinoline nucleus. They are derived from the amino acids like tyrosine and phenylalanine. http://purl.obolibrary.org/obo/CHEBI_25000 lactone http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. http://purl.obolibrary.org/obo/CHEBI_25238 methoxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzene Any benzoic acid carrying one or more methoxy substituents. http://purl.obolibrary.org/obo/CHEBI_25409 monoterpenoid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid Any terpenoid derived from a monoterpene. The term includes compounds in which the C10 skeleton of the parent monoterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). http://purl.obolibrary.org/obo/CHEBI_25512 neurotransmitter http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. http://purl.obolibrary.org/obo/CHEBI_25698 ether http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound An organooxygen compound with formula ROR, where R is not hydrogen. http://purl.obolibrary.org/obo/CHEBI_26191 polyol http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound A compound that contains two or more hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_26377 pterocarpans http://purl.obolibrary.org/obo/CHEBI_38834 benzofurochromene Members of the class of benzofurochromene with a 6a,11a-dihydro-6H-[1]benzofuro[3,2-c]chromene skeleton and its substituted derivatives. They generally bear structural resemblance to isoflavanoids that possess antibiotic activity and are produced by plant tissues in response to infection. They are the 3,4-dihydroderivatives of coumestans. http://purl.obolibrary.org/obo/CHEBI_26773 stigmastane http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent A steroid fundamental parent that has formula C29H52. http://purl.obolibrary.org/obo/CHEBI_27024 toluenes http://purl.obolibrary.org/obo/CHEBI_22712 benzenes Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group. http://purl.obolibrary.org/obo/CHEBI_27311 volatile oil component http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite that is found naturally as a component of a volatile oil. http://purl.obolibrary.org/obo/CHEBI_27386 cinnamic acid http://purl.obolibrary.org/obo/CHEBI_23252 cinnamic acids A monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. It is found in Cinnamomum cassia. http://purl.obolibrary.org/obo/CHEBI_27667 beta-D-galactose http://purl.obolibrary.org/obo/CHEBI_4139 D-galactopyranose A D-galactopyranose having beta-configuration at the anomeric centre. http://purl.obolibrary.org/obo/CHEBI_28842 stearic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics. http://purl.obolibrary.org/obo/CHEBI_28875 tetradecanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain, fourteen-carbon, long-chain saturated fatty acid mostly found in milk fat. http://purl.obolibrary.org/obo/CHEBI_33261 organosulfur compound http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity An organosulfur compound is a compound containing at least one carbon-sulfur bond. http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity An organic compound having at least one hydroxy group attached to a carbon atom. http://purl.obolibrary.org/obo/CHEBI_33823 enol http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound Alkenols; the term refers specifically to vinylic alcohols, which have the structure HOCR'=CR2. Enols are tautomeric with aldehydes (R' = H) or ketones (R' =/= H). http://purl.obolibrary.org/obo/CHEBI_35187 monoterpene http://purl.obolibrary.org/obo/CHEBI_35186 terpene A C10 terpene. http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene, so may be considered as triterpenoids. http://purl.obolibrary.org/obo/CHEBI_36054 benzoate ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Esters of benzoic acid or substituted benzoic acids. http://purl.obolibrary.org/obo/CHEBI_36055 furoic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A monocarboxylic acid that consists of a furan ring having a single carboxylic acid group on any ring position and derivatives thereof. http://purl.obolibrary.org/obo/CHEBI_36233 disaccharide http://purl.obolibrary.org/obo/CHEBI_50699 oligosaccharide A compound in which two monosaccharides are joined by a glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_36481 oleanane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A triterpene that has formula C30H52. http://purl.obolibrary.org/obo/CHEBI_36740 alpha-pinene http://purl.obolibrary.org/obo/CHEBI_17187 pinene A pinene that is bicyclo[3.1.1]hept-2-ene substituted by methyl groups at positions 2, 6 and 6 respectively. http://purl.obolibrary.org/obo/CHEBI_36785 carbobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound A bicyclic compound in which all the ring atoms are carbon. http://purl.obolibrary.org/obo/CHEBI_36786 tetralins http://purl.obolibrary.org/obo/CHEBI_36785 carbobicyclic compound Compounds containing a tetralin skeleton. http://purl.obolibrary.org/obo/CHEBI_38032 carbotricyclic compound http://purl.obolibrary.org/obo/CHEBI_51959 organic tricyclic compound A carbopolyclic compound comprising of three carbocyclic rings. http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms. http://purl.obolibrary.org/obo/CHEBI_38260 pyrrolidines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound Any of a class of heterocyclic amines having a saturated five-membered ring. http://purl.obolibrary.org/obo/CHEBI_39236 alpha-farnesene http://purl.obolibrary.org/obo/CHEBI_39237 farnesene A farnesene that is 1,3,6,10-tetraene substituted by methyl groups at positions 3, 7 and 11 respectively. http://purl.obolibrary.org/obo/CHEBI_48318 fragrance http://purl.obolibrary.org/obo/CHEBI_33232 application A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell. http://purl.obolibrary.org/obo/CHEBI_49201 anti-ulcer drug http://purl.obolibrary.org/obo/CHEBI_23888 drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. http://purl.obolibrary.org/obo/CHEBI_50025 beta-pinene http://purl.obolibrary.org/obo/CHEBI_17187 pinene An isomer of pinene with an exocyclic double bond. It is a component of essential oils from many plants. http://purl.obolibrary.org/obo/CHEBI_50218 EC 3.1.4.* (phosphoric diester hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76760 EC 3.1.* (ester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*). http://purl.obolibrary.org/obo/CHEBI_50268 GABA modulator http://purl.obolibrary.org/obo/CHEBI_51374 GABA agent A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. http://purl.obolibrary.org/obo/CHEBI_50753 isoflavonoid http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid Any 1-benzopyran with an aryl substituent at position 3. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds. http://purl.obolibrary.org/obo/CHEBI_50902 genotoxin http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. http://purl.obolibrary.org/obo/CHEBI_50904 allergen http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. http://purl.obolibrary.org/obo/CHEBI_51681 dimethoxybenzene http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzene Any methoxybenzene that consists of a benzene skeleton substituted with two methoxy groups and its derivatives. http://purl.obolibrary.org/obo/CHEBI_55324 gastrointestinal drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug used for its effects on the gastrointestinal system, e.g. controlling gastric acidity, regulating gastrointestinal motility and water flow, and improving digestion. http://purl.obolibrary.org/obo/CHEBI_5686 heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclic compound having as ring members atoms of at least two different elements. http://purl.obolibrary.org/obo/CHEBI_59163 biomarker http://purl.obolibrary.org/obo/CHEBI_47867 indicator A substance used as an indicator of a biological state. http://purl.obolibrary.org/obo/CHEBI_62508 eudesmane sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid Any sesquiterpenoid having a eudesmane skeleton. http://purl.obolibrary.org/obo/CHEBI_63191 beta-caryophyllene http://purl.obolibrary.org/obo/CHEBI_35428 ortho-fused bicyclic hydrocarbon A sesquiterpene with a [7.2.0]-bicyclic structure comprising fused 9- and 4-membered rings, with a trans-ring junction, a trans-double bond between the 4- and 5-positions of the 9-membered ring, a methylidene group at position 9, and methyl groups at positions 3, 11, and 11. The most commonly occurring form is the (1R,9S)-(-)-enantiomer, which is found in many essential oils, particularly clove oil. http://purl.obolibrary.org/obo/CHEBI_64915 antiplasmodial drug http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria. http://purl.obolibrary.org/obo/CHEBI_67079 anti-inflammatory agent http://purl.obolibrary.org/obo/CHEBI_33232 application Any compound that has anti-inflammatory effects. http://purl.obolibrary.org/obo/CHEBI_67200 provitamin A http://purl.obolibrary.org/obo/CHEBI_50188 provitamin A provitamin that can be converted into vitamin A by enzymes from animal tissues. http://purl.obolibrary.org/obo/CHEBI_72544 flavonoids http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them. http://purl.obolibrary.org/obo/CHEBI_76956 Aspergillus metabolite http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus. http://purl.obolibrary.org/obo/CHEBI_76967 human xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. http://purl.obolibrary.org/obo/CHEBI_78308 asarone http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzene A phenylpropanoid that is benzene substituted by methoxy groups at positions 1, 2 and 4 and a propen-1-yl group at position 5. It has been isolated from Acorus. http://purl.obolibrary.org/obo/CHEBI_83056 Daphnia magna metabolite http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite A Daphnia metabolite produced by the species Daphnia magna. http://purl.obolibrary.org/obo/CHEBI_114185 (3bR,9bS)-6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e]isobenzofuran-1-one http://purl.obolibrary.org/obo/CHEBI_35789 oxo steroid An oxo steroid that has formula C20H24O3. http://purl.obolibrary.org/obo/CHEBI_15904 long-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid A fatty acid with a chain length ranging from C13 to C22. http://purl.obolibrary.org/obo/CHEBI_16739 2-furoate http://purl.obolibrary.org/obo/CHEBI_36056 furancarboxylate A furancarboxylate that is the conjugate base of 2-furoic acid. http://purl.obolibrary.org/obo/CHEBI_16810 2-oxoglutarate(2-) http://purl.obolibrary.org/obo/CHEBI_36147 oxo dicarboxylate An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid. http://purl.obolibrary.org/obo/CHEBI_16918 gallate http://purl.obolibrary.org/obo/CHEBI_36085 trihydroxybenzoate A trihydroxybenzoate that is the conjugate base of gallic acid. http://purl.obolibrary.org/obo/CHEBI_22743 benzyl alcohols http://purl.obolibrary.org/obo/CHEBI_33854 aromatic alcohol Compounds containing a phenylmethanol skeleton. http://purl.obolibrary.org/obo/CHEBI_24684 hydroxybutyric acid http://purl.obolibrary.org/obo/CHEBI_24654 hydroxy fatty acid Any compound comprising a butyric acid core carrying at least one hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_38716 carboxylic acid dianion A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_29749 ferulate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion obtained by the deprotonation of the carboxy group of ferulic acid. http://purl.obolibrary.org/obo/CHEBI_29806 fumarate(2-) http://purl.obolibrary.org/obo/CHEBI_36180 butenedioate A C4-dicarboxylate that is the E-isomer of but-2-enedioate(2-) http://purl.obolibrary.org/obo/CHEBI_30921 glutarate(2-) http://purl.obolibrary.org/obo/CHEBI_24329 glutarate A dicarboxylic acid dianion obtained by deprotonation of both the carboxy groups of glutaric acid. http://purl.obolibrary.org/obo/CHEBI_33707 gamma-amino acid http://purl.obolibrary.org/obo/CHEBI_83820 non-proteinogenic amino acid A non-proteinogenic amino-acid in which the amino group is located on the carbon atom at the position gamma to the carboxy group. http://purl.obolibrary.org/obo/CHEBI_37699 protein kinase inhibitor http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases. http://purl.obolibrary.org/obo/CHEBI_38756 methoxyisoflavone http://purl.obolibrary.org/obo/CHEBI_38757 isoflavones Members of the class of isoflavones with at least one methoxy substituent. http://purl.obolibrary.org/obo/CHEBI_47868 photosensitizing agent http://purl.obolibrary.org/obo/CHEBI_23888 drug A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells. http://purl.obolibrary.org/obo/CHEBI_50263 2-hydroxydicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid Any dicarboxylic acid carrying a hydroxy group on the carbon atom at position alpha to the carboxy group. http://purl.obolibrary.org/obo/CHEBI_64049 food acidity regulator http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents. http://purl.obolibrary.org/obo/CHEBI_64345 MALDI matrix material http://purl.obolibrary.org/obo/CHEBI_33232 application A compound used to form the matrix for MALDI (matrix-assisted laser desorption/ionization) mass spectrometry. MALDI matrix materials are crystalline compounds with a fairly low molecular weight, so as to allow facile vaporization, have strong absorption at UV or IR wavelengths (to rapidly and efficiently absorb laser irradiation), generally contain polar groups (enabling them to be used in aqueous solutions) and are frequently acidic (so assisting ionisation of the compound being studied, which is contained within the matrix material). http://purl.obolibrary.org/obo/CHEBI_68494 apoptosis inhibitor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. http://purl.obolibrary.org/obo/CHEBI_74783 astringent http://purl.obolibrary.org/obo/CHEBI_23888 drug A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions. http://purl.obolibrary.org/obo/CHEBI_77307 cardioprotective agent http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any protective agent that is able to prevent damage to the heart. http://purl.obolibrary.org/obo/CHEBI_131619 C27-steroid http://purl.obolibrary.org/obo/CHEBI_35341 steroid A steroid compound with a structure based on a 27-carbon (cholestane) skeleton. http://purl.obolibrary.org/obo/CHEBI_131699 EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_38234 DNA polymerase inhibitor A DNA polymerase inhibitor that interferes with the action of a DNA-directed DNA polymerase (EC 2.7.7.7). http://purl.obolibrary.org/obo/CHEBI_131702 stigmastane derivative http://purl.obolibrary.org/obo/CHEBI_35341 steroid Any steroid (or derivative) based on a stigmastane skeleton. http://purl.obolibrary.org/obo/CHEBI_131703 stigmastane sterol http://purl.obolibrary.org/obo/CHEBI_15889 sterol Any sterol based on a stigmastane skeleton. http://purl.obolibrary.org/obo/CHEBI_131900 pyranopyran http://purl.obolibrary.org/obo/CHEBI_36587 organic oxo compound Any organic heterobicyclic compound containing two ortho-fused pyran rings. http://purl.obolibrary.org/obo/CHEBI_131927 dicarboxylic acids and O-substituted derivatives http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens. http://purl.obolibrary.org/obo/CHEBI_13209 long-chain fatty acid ethyl ester http://purl.obolibrary.org/obo/CHEBI_78206 fatty acid ethyl ester A fatty acid ethyl ester resulting from the formal condensation of the carboxy group of a long-chain fatty acid with the hydroxy group of ethanol. http://purl.obolibrary.org/obo/CHEBI_132150 wilforine http://purl.obolibrary.org/obo/CHEBI_38164 organic heteropentacyclic compound An organic heteropentacyclic compound and pyridine alkaloid with formula C43H49NO18 originally isolated from the roots of Tripterygium wilfordii. http://purl.obolibrary.org/obo/CHEBI_132152 triptofordin C 2 http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle A dihydroagarofuran sesquiterpenoid that is isolated from Tripterygium wilfordii. http://purl.obolibrary.org/obo/CHEBI_132186 celacinnine http://purl.obolibrary.org/obo/CHEBI_24995 lactam A spermidine alkaloid that is isolated from Maytenus heterophylla and Maytenus senegalensis. http://purl.obolibrary.org/obo/CHEBI_132267 triptonide http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone A diterpene triepoxide that is triptobenzene K in which the acylhydroquinone moiety has undergone oxidation to the corresponding triepoxyketone derivative. It has been isolated from the roots of Tripterygium wilfordii. http://purl.obolibrary.org/obo/CHEBI_132314 Demethylzeylasteral http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity pubchem.ncbi.nlm.nih.gov/compound/10322911 http://purl.obolibrary.org/obo/CHEBI_132315 Triptohypol A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity pubchem.ncbi.nlm.nih.gov/compound/101936043 http://purl.obolibrary.org/obo/CHEBI_132333 triptolidenol http://purl.obolibrary.org/obo/CHEBI_37581 gamma-lactone A tetracyclic diterpenoid that is isolated from Tripterygium wilfordii and exhibits anti-inflammatory properties. http://purl.obolibrary.org/obo/CHEBI_132334 Wilforgine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity pubchem.ncbi.nlm.nih.gov/compound/124030 http://purl.obolibrary.org/obo/CHEBI_132336 triptriolide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/58636974 http://purl.obolibrary.org/obo/CHEBI_132337 triptoditerpenic acid B http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/192372#section=Top http://purl.obolibrary.org/obo/CHEBI_132338 triptohypol B http://purl.obolibrary.org/obo/CHEBI_51689 enone http://pubchem.ncbi.nlm.nih.gov/compound/101936044 http://purl.obolibrary.org/obo/CHEBI_132339 triptohypol D http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101062653 http://purl.obolibrary.org/obo/CHEBI_132340 triptohypol C http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10411574 http://purl.obolibrary.org/obo/CHEBI_132341 hypodiol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101936045#section=Top http://purl.obolibrary.org/obo/CHEBI_132342 triptohypol E http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/44559123 http://purl.obolibrary.org/obo/CHEBI_132343 Triptohypol F http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/91895434 http://purl.obolibrary.org/obo/CHEBI_132344 celastolide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101936042 http://purl.obolibrary.org/obo/CHEBI_132345 Canophyllal http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/586214 http://purl.obolibrary.org/obo/CHEBI_132346 neotriptophenolide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/133766#section=Top http://purl.obolibrary.org/obo/CHEBI_132347 triptonolide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/133221#section=Top http://purl.obolibrary.org/obo/CHEBI_132348 triptonoterpene http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone An abietane diterpenoid that is abieta-8(14),9(11),12-triene substituted at positions 3 and 14 respectively by oxo and hydroxy groups. It is found in Tripterygium wilfordii. http://purl.obolibrary.org/obo/CHEBI_132349 triptobenzene A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/15762008 http://purl.obolibrary.org/obo/CHEBI_132350 triptobenzene D http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101712250 http://purl.obolibrary.org/obo/CHEBI_132351 Triptobenzene H http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/53363843 http://purl.obolibrary.org/obo/CHEBI_132352 triptoquinone A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/132524#section=Top http://purl.obolibrary.org/obo/CHEBI_132353 triptoquinone B http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/11724191 http://purl.obolibrary.org/obo/CHEBI_132354 triptoquinone H http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101062652 http://purl.obolibrary.org/obo/CHEBI_132365 EC 1.14.11.2 (procollagen-proline dioxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76902 EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor An EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor that interferes with the action of procollagen-proline dioxygenase (EC 1.14.11.2). http://purl.obolibrary.org/obo/CHEBI_132367 acceptor beta-D-glucuronoside(1-) http://purl.obolibrary.org/obo/CHEBI_63551 carbohydrate acid derivative anion From EC 2.4.1.17: This entry denotes a family of enzymes accepting a wide range of substrates, including phenols, alcohols, amines and fatty acids. So R can also 'start' with an N http://purl.obolibrary.org/obo/CHEBI_132370 triptotriterpenic acid A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/127707 http://purl.obolibrary.org/obo/CHEBI_132371 triptocallic acid D http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/44575705#section=Top http://purl.obolibrary.org/obo/CHEBI_132372 triptocallic acid C http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101937091 http://purl.obolibrary.org/obo/CHEBI_132373 mesembryanthemoidigenic acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/6452118 http://purl.obolibrary.org/obo/CHEBI_132374 29-hydroxyfriedelan-3-one http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/91895429 http://purl.obolibrary.org/obo/CHEBI_132375 wilforic acid C http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101707494 http://purl.obolibrary.org/obo/CHEBI_132376 Wilforic acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101707492 http://purl.obolibrary.org/obo/CHEBI_132378 wilforol A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10096097 http://purl.obolibrary.org/obo/CHEBI_132379 wilforol B http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10366522 http://purl.obolibrary.org/obo/CHEBI_132380 cangoronin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/9869964#section=Top http://purl.obolibrary.org/obo/CHEBI_132381 2-O-deacetyleuonine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101408619 http://purl.obolibrary.org/obo/CHEBI_132382 tripfordine C http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101416498 http://purl.obolibrary.org/obo/CHEBI_132383 wilfordinine A http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium wilfordii and Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132384 wilfordinine B http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium wilfordii and Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132385 wilfordinine C http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium wilfordii and Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132386 wilformine http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium wilfordii and exhibits immunosuppressive and insecticidal properties. http://purl.obolibrary.org/obo/CHEBI_132387 wilfornine A http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium wilfordii. http://purl.obolibrary.org/obo/CHEBI_132388 hyponine D http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132389 hyponine E http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132390 hyponine F http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132392 neoeuonymine http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Euonymus Sieboldiana. http://purl.obolibrary.org/obo/CHEBI_132393 forrestine http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium forrestii, Platanus chiapensis and Maytenus chiapensis. http://purl.obolibrary.org/obo/CHEBI_132394 hypoglaunine C http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium hypoglaucum and Tripterygium wilfordii. http://purl.obolibrary.org/obo/CHEBI_132395 cangorinine E-1 http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is isolated from Tripterygium wilfordii. http://purl.obolibrary.org/obo/CHEBI_132396 regelidine http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle A sesquiterpene alkaloid that is isolated from the stem of Tripterygium regelii. http://purl.obolibrary.org/obo/CHEBI_132399 3-epi-fagomine http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A member of the class of hydroxypiperidines that is piperidine carrying a hydroxymethyl substituent at position 2 as well as two hydroxy substituents at positions 3 and 4 (the 2R,3R,4S-diastereomer). http://purl.obolibrary.org/obo/CHEBI_132401 marmesinin http://purl.obolibrary.org/obo/CHEBI_26369 psoralens A member of the class of psoralens that is (-)-marmesin in which the hydroxy hydrogen is replaced by a beta-D-glucosyl residue. http://purl.obolibrary.org/obo/CHEBI_132402 angelitriol http://purl.obolibrary.org/obo/CHEBI_27136 triol A member of the class of coumarins that is 7-methoxycoumarin in which the hydrogen at position 6 has been replaced by a 1,2,3-trihydroxy-3-methylbutyl group (the 1R,2S stereoisomer). Originally isolated from the roots of Angelica pubescens, angelitriol shows strong inhibitory effects on human platelet aggregation. http://purl.obolibrary.org/obo/CHEBI_132482 triptobenzene K http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone A tetracyclic diterpenoid with fromula C20H22O5, originally isolated from the dried root outer bark of Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132483 triptonoterpene methyl ether http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone An abietane diterpenoid that is abieta-8(14),9(11),12-triene substituted at positions 3, 11 and 14 respectively by oxo, hydroxy and methoxy groups. It is found in Tripterygium wilfordii and Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_132512 wilforidine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101335371 http://purl.obolibrary.org/obo/CHEBI_132513 celafurine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/15346742 http://purl.obolibrary.org/obo/CHEBI_132518 EC 3.2.1.23 (beta-galactosidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_52424 EC 3.2.1.* (glycosidase) inhibitor An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of beta-galactosidase (EC 3.2.1.23). http://purl.obolibrary.org/obo/CHEBI_132613 triptonoterpenol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/159330 http://purl.obolibrary.org/obo/CHEBI_132614 triptohairic acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/100929735 http://purl.obolibrary.org/obo/CHEBI_132615 orthosphenic acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/20056194#section=Top http://purl.obolibrary.org/obo/CHEBI_132616 triptotriterpenic acid B http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/195563 http://purl.obolibrary.org/obo/CHEBI_132617 triptotriterpenic acid C http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/130072 http://purl.obolibrary.org/obo/CHEBI_132618 triptotritepenonic acid A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/192337 http://purl.obolibrary.org/obo/CHEBI_132619 regelin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/163808 http://purl.obolibrary.org/obo/CHEBI_132620 6alpha-hydroxycholestanol http://purl.obolibrary.org/obo/CHEBI_36850 6alpha-hydroxy steroid A sterol that is cholestanol in which the hydrogen at the 6alpha position has been replaced by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_132621 16-hydroxytriptolide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/126556 http://purl.obolibrary.org/obo/CHEBI_132622 triptophenolide methyl ether http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/156286 http://purl.obolibrary.org/obo/CHEBI_132623 nodakenetin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/26305 http://purl.obolibrary.org/obo/CHEBI_132624 Columbianadin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/6436246 http://purl.obolibrary.org/obo/CHEBI_132625 CHEMBL299099 http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10659145#section=Top http://purl.obolibrary.org/obo/CHEBI_132626 columbianetin acetate http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/161409 http://purl.obolibrary.org/obo/CHEBI_132627 (+)-Angenomalin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/51520704#section=Top http://purl.obolibrary.org/obo/CHEBI_132628 isotalatizidine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/11452543 http://purl.obolibrary.org/obo/CHEBI_132629 neoline http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/120682 http://purl.obolibrary.org/obo/CHEBI_132630 benzoylmesaconine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/24832657 http://purl.obolibrary.org/obo/CHEBI_132631 senbusine A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/100930481 http://purl.obolibrary.org/obo/CHEBI_132632 hukbusine A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/102375480 http://purl.obolibrary.org/obo/CHEBI_132633 benzoylaconine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/78358486 http://purl.obolibrary.org/obo/CHEBI_132634 benzoylhypaconine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/78358526 http://purl.obolibrary.org/obo/CHEBI_132635 neojiangyouaconitine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/78358553 http://purl.obolibrary.org/obo/CHEBI_132636 deoxyaconitine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/6426870 http://purl.obolibrary.org/obo/CHEBI_132637 foresaconitine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/92044468 http://purl.obolibrary.org/obo/CHEBI_132638 crassicauline A http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/157539 http://purl.obolibrary.org/obo/CHEBI_132639 aconine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/20054813 http://purl.obolibrary.org/obo/CHEBI_132640 yunaconitine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/11250863 http://purl.obolibrary.org/obo/CHEBI_132641 chasmanine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/20055812 http://purl.obolibrary.org/obo/CHEBI_132642 foresticine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/185130 http://purl.obolibrary.org/obo/CHEBI_132643 N-deethylaconine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101552717 http://purl.obolibrary.org/obo/CHEBI_132644 hypaconine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101671038 http://purl.obolibrary.org/obo/CHEBI_132645 mesaconine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101671037 http://purl.obolibrary.org/obo/CHEBI_132646 oxonitine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/6708531 http://purl.obolibrary.org/obo/CHEBI_132647 futoenone http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/9819306 http://purl.obolibrary.org/obo/CHEBI_132648 galgravin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101749 http://purl.obolibrary.org/obo/CHEBI_132649 Acuminatin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/6441048 http://purl.obolibrary.org/obo/CHEBI_132650 burchellin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/100199 http://purl.obolibrary.org/obo/CHEBI_132651 kadsurenin C http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/45487142 http://purl.obolibrary.org/obo/CHEBI_132652 kadsurenin K http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3083438 http://purl.obolibrary.org/obo/CHEBI_132653 kaadsurenin L http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3083437 http://purl.obolibrary.org/obo/CHEBI_132654 kadsurenin M http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/208856 http://purl.obolibrary.org/obo/CHEBI_132655 Terpinen-4-ol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/11230 http://purl.obolibrary.org/obo/CHEBI_132656 gamma-Elemene http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/6432312 http://purl.obolibrary.org/obo/CHEBI_132657 piperlactam S http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/622222 http://purl.obolibrary.org/obo/CHEBI_132658 pipataline http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/9922008 http://purl.obolibrary.org/obo/CHEBI_132659 isostrychnine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/11024113 http://purl.obolibrary.org/obo/CHEBI_132660 isobrucine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3081763 http://purl.obolibrary.org/obo/CHEBI_132661 Isostrychnine N-oxide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/15631900 http://purl.obolibrary.org/obo/CHEBI_132662 Isobrucine N-oxide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101532797 http://purl.obolibrary.org/obo/CHEBI_132663 protostrychnine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101282059 http://purl.obolibrary.org/obo/CHEBI_132664 isopseudostrychnine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101575887 http://purl.obolibrary.org/obo/CHEBI_132665 Stryvomitine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101575886 http://purl.obolibrary.org/obo/CHEBI_132666 pseudostrychnine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/21723446 http://purl.obolibrary.org/obo/CHEBI_132667 pseudobrucine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3083630 http://purl.obolibrary.org/obo/CHEBI_132668 icajine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3083907 http://purl.obolibrary.org/obo/CHEBI_132669 novacine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10365034 http://purl.obolibrary.org/obo/CHEBI_132670 14-hydroxyicajine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/210990 http://purl.obolibrary.org/obo/CHEBI_132696 alpha-colubrine http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether A monoterpenoid indole alkaloid that is strychnine in which the hydrogen at position 3 has been replaced by a methoxy group. It is a minor alkaloid from Strychnos nux-vomica. http://purl.obolibrary.org/obo/CHEBI_132697 beta-colubrine http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether A monoterpenoid indole alkaloid that is strychnine in which the hydrogen at position 2 has been replaced by a methoxy group. It is a minor alkaloid from Strychnos nux-vomica. http://purl.obolibrary.org/obo/CHEBI_132699 10-Hydroxylicajine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/57412271 http://purl.obolibrary.org/obo/CHEBI_132700 11-Hydroxylicajine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/57412270 http://purl.obolibrary.org/obo/CHEBI_132702 5-Hydroxylvomicine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101575888 http://purl.obolibrary.org/obo/CHEBI_132703 strychnine N-oxide http://purl.obolibrary.org/obo/CHEBI_65323 monoterpenoid indole alkaloid An N-oxide resulting from the oxidation of the non-acylated nitrogen of strychnine. It is a metabolite of strychnine. http://purl.obolibrary.org/obo/CHEBI_132705 2-Hydroxy-3-methoxystrychnine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/21680050 http://purl.obolibrary.org/obo/CHEBI_132707 5-Oxobrucine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/57412268 http://purl.obolibrary.org/obo/CHEBI_132709 loganoside http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/91727262 http://purl.obolibrary.org/obo/CHEBI_132712 Secoxyloganin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/162868 http://purl.obolibrary.org/obo/CHEBI_132714 ethyl trans-caffeate http://purl.obolibrary.org/obo/CHEBI_23990 ethyl ester An ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. http://purl.obolibrary.org/obo/CHEBI_132715 stepharine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/98455 http://purl.obolibrary.org/obo/CHEBI_132718 stepharanine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10358881 http://purl.obolibrary.org/obo/CHEBI_132719 bianfugenine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/137399 http://purl.obolibrary.org/obo/CHEBI_132720 sinomendine http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/11759516 http://purl.obolibrary.org/obo/CHEBI_132721 dl-syrngaresinol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/100067 http://purl.obolibrary.org/obo/CHEBI_132788 paeoninorigenone http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/133475 http://purl.obolibrary.org/obo/CHEBI_132789 Oxypaeoniflorin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/21631105 http://purl.obolibrary.org/obo/CHEBI_132790 alpha-benzoyloxypaeoniflorin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/46883189 http://purl.obolibrary.org/obo/CHEBI_132791 beta-benzoyloxypaeoniflorin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/46883190 http://purl.obolibrary.org/obo/CHEBI_132792 (+)-Lactiflorin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/14605198 http://purl.obolibrary.org/obo/CHEBI_132793 albiforin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/24868421 http://purl.obolibrary.org/obo/CHEBI_132794 Pinen-10-yl vicianoside http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3036428#section=Top http://purl.obolibrary.org/obo/CHEBI_132795 Lactinolide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/14336593 http://purl.obolibrary.org/obo/CHEBI_132796 paeonilactinone http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A cyclic monoterpene ketone that is bicyclo[3.1.1]heptan-2-one which is substituted at positions 4, 6, and 6 by hydroxymethyl, methyl, and methyl groups (the 1R,4S,5R stereoisomer). It has been found in Japanese Paeoniae Radix, which has been used in various Chinese medicinal preparations as an anodyne, sedative, antispasmodic, and astringent. http://purl.obolibrary.org/obo/CHEBI_132815 6'-O-Acetylpaeoniflorin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/21575212 http://purl.obolibrary.org/obo/CHEBI_132816 6'-O-Galloylalbiflorin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/102516500 http://purl.obolibrary.org/obo/CHEBI_132817 Paeoniflorin Sulfonate http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101382399 http://purl.obolibrary.org/obo/CHEBI_132819 Trachelosperogenin B http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/23259303 http://purl.obolibrary.org/obo/CHEBI_132820 Matairesinoside http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/486612 http://purl.obolibrary.org/obo/CHEBI_132821 Epipinoresinol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/637584 http://purl.obolibrary.org/obo/CHEBI_132822 Salicifoliol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/102275941 http://purl.obolibrary.org/obo/CHEBI_132823 Clionasterol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/457801 http://purl.obolibrary.org/obo/CHEBI_132824 Spathulenol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/522266 http://purl.obolibrary.org/obo/CHEBI_132825 Aristoloterpenate-I http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10347702 http://purl.obolibrary.org/obo/CHEBI_132826 Versicolactone B http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/6438997 http://purl.obolibrary.org/obo/CHEBI_132827 Camphenilone http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/93073 http://purl.obolibrary.org/obo/CHEBI_132828 Isobornyl Formate http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/23623868 http://purl.obolibrary.org/obo/CHEBI_132829 delta-Terpineolacetate http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/91691738 http://purl.obolibrary.org/obo/CHEBI_132830 delta-Elemene http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/12309449 http://purl.obolibrary.org/obo/CHEBI_132831 beta-Maaliene http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101596917 http://purl.obolibrary.org/obo/CHEBI_132832 gurjunele http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/15560275 http://purl.obolibrary.org/obo/CHEBI_132833 L-Epicatechin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/1203 http://purl.obolibrary.org/obo/CHEBI_132835 naringenin 7-O-beta-D-glucuronide http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol A dihydroxyflavanone that is naringenin in which the phenolic hydrogen at position 7 has been replaced by a beta-D-glucuronosyl residue. http://purl.obolibrary.org/obo/CHEBI_132837 (E,E)-hepta-2,4-dienal http://purl.obolibrary.org/obo/CHEBI_51921 heptadienal A heptadienal in which the two double bonds are located at positions 2 and 4 (the E,E-geoisomer). http://purl.obolibrary.org/obo/CHEBI_132838 3-hydroxyheptanoic acid http://purl.obolibrary.org/obo/CHEBI_59554 medium-chain fatty acid A 3-hydroxy fatty acid that is heptanoic acid in which one of the hydrogens at position 3 is replaced by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_132839 (2R,5S)-linalyl oxide http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound A monoterpenoid that is 2-(2-hydroxypropan-2-yl)oxolane carying additional methyl and vinyl substituents both located at position 5 (the 2R,5S-diastereomer). http://purl.obolibrary.org/obo/CHEBI_132843 (E)-2-undecenal http://purl.obolibrary.org/obo/CHEBI_133173 2-undecenal A 2-undecenal in which the C=C bond has E configuration. http://purl.obolibrary.org/obo/CHEBI_132844 GLYCIDYL METHACRYLATE http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/7837 http://purl.obolibrary.org/obo/CHEBI_132845 (Z)-hex-3-en-1-yl methyl carbonate http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound A carbonate ester that is dimethyl carbonate in which one of the methyl groups has been replaced by a (Z)-hex-3-en-1-yl group. It has a floral scent and is used in the production of fruit or vegetable-like flavour additives. http://purl.obolibrary.org/obo/CHEBI_132846 8-Methyl-1-undecene http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/522552 http://purl.obolibrary.org/obo/CHEBI_132847 1-p-Menthene http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/21671 http://purl.obolibrary.org/obo/CHEBI_132848 Linaloyl Oxide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/522514 http://purl.obolibrary.org/obo/CHEBI_132849 Lauric Anhydride http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/69527 http://purl.obolibrary.org/obo/CHEBI_132850 trifloroside http://purl.obolibrary.org/obo/CHEBI_33853 phenols A secoiridoid glycoside that is (4aS,5R,6R)-6-hydroxy-5-vinyl-4,4a,5,6-tetrahydro-1H,3H-pyrano[3,4-c]pyran-1-one in which the hydroxy group has been converted to the corresponding 2,3,6-tri-O-acetyl-beta-D-glucoside, the 4-hydroxy group of which has been esterified by formal condensation with the carboxy group of 2,3-dihydroxybenzoic acid 3-beta-D-glucoside. It is a component of Gentiana scabra root extract, which is used as an internal remedy in traditional Korean medicine for the treatment of diabetes mellitus. http://purl.obolibrary.org/obo/CHEBI_132851 Roburic Acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/12315005 http://purl.obolibrary.org/obo/CHEBI_132852 lespedezol D1 http://purl.obolibrary.org/obo/CHEBI_38163 organic heterotetracyclic compound A member of the class of pterocarpans that is (6aR,11aR)-3,9-dihydroxypterocarpan in which the hydrogen at position 8 has been replaced by a methoxy group. http://purl.obolibrary.org/obo/CHEBI_132853 acteoside http://purl.obolibrary.org/obo/CHEBI_36087 cinnamate ester A glycoside that is the alpha-L-rhamnosyl-(1->3)-beta-D-glucoside of hydroxytyrosol in which the hydroxy group at position 4 of the glucopyranosyl moiety has undergone esterification by formal condensation with trans-caffeic acid. http://purl.obolibrary.org/obo/CHEBI_132854 9-hydroxyundec-10-enoic acid http://purl.obolibrary.org/obo/CHEBI_131869 hydroxy monounsaturated fatty acid A hydroxy monounsaturated fatty acid that is undec-10-enoic acid which is substituted by a hydroxy group at position 9. It has been isolated from the leaves of Corchorus olitorius, also known as the medicinal foodstuff moroheiya. http://purl.obolibrary.org/obo/CHEBI_132856 Viscumneoside I http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/42608078 http://purl.obolibrary.org/obo/CHEBI_132857 Viscumneoside III http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/195287 http://purl.obolibrary.org/obo/CHEBI_132858 Viscumneoside IV http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/5492426 http://purl.obolibrary.org/obo/CHEBI_132859 Viscumneoside V http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/195288 http://purl.obolibrary.org/obo/CHEBI_132860 Viscumneoside VI http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3082946 http://purl.obolibrary.org/obo/CHEBI_132861 Viscumneoside VII http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/5748462 http://purl.obolibrary.org/obo/CHEBI_132863 coriatin http://purl.obolibrary.org/obo/CHEBI_38163 organic heterotetracyclic compound A sesquiterpene lactone containing two epoxide groups and two tertiary hydroxy groups that has been isolated from the roots of Coriaria nepalensis. http://purl.obolibrary.org/obo/CHEBI_132864 Corianin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10880921 http://purl.obolibrary.org/obo/CHEBI_132865 Kaurenoic Acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/73062 http://purl.obolibrary.org/obo/CHEBI_132866 Deoxyfuconojirimycin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/122618 http://purl.obolibrary.org/obo/CHEBI_132867 1-DEOXYNOJIRIMYCIN http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/29435 http://purl.obolibrary.org/obo/CHEBI_132868 cyclomorusin A http://purl.obolibrary.org/obo/CHEBI_38164 organic heteropentacyclic compound An extended flavonoid that is cyclomulberrin in which the hydroxy group at position 10 has undergone oxidative cyclisation to position 3 of the 3-methylbut-2-en-1-yl substituent, with migration of the double bond into conjugation with the aromatic ring. It is a moderate inhibitor of acetylcholinesterase (IC50 = 16.2 - 36.6 muM), and a strong inhibitor of platelet-activating factor (PAF; 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) induced platelet aggregation. http://purl.obolibrary.org/obo/CHEBI_132869 cyclomulberrin http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone A extended flavonoid that is 6H,7H-chromeno[4,3-b]chromen-7-one which is substituted by a 2-methylprop-1-en-1-yl group at position 6, a 3-methylbut-2-en-1-yl group at position 11, and hydroxy groups at positions 3, 8, and 10. It is found in the bark of Morus species and has been reported to protect human neuronal cells derived from the human neuroblastoma SH-SY5Y cell line. http://purl.obolibrary.org/obo/CHEBI_132870 (-)-homalomenol C http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound An organic heterotricyclic compound and sesquiterpenoid that is 11-oxatricyclo[5.3.1.0(2,6)]undecane-1,8-diol which is substituted by methyl groups at positions 5 and 8, and by an isopropyl group at position 5. The absolute stereochemistry is not known; it is either 1R,2S,5R,6R,7R,8R (as shown), or the enantiomer. http://purl.obolibrary.org/obo/CHEBI_132871 (-)-homalomenol D http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound An organic heterotricyclic compound and sesquiterpenoid that is 11-oxatricyclo[5.3.1.0(2,6)]undecan-8-ol which is substituted by methyl groups at positions 2 and 8, and by an isopropyl group at position 5. The absolute stereochemistry is not known; it is either 1R,2R,5S,6S,7R,8R (as shown), or the enantiomer. http://purl.obolibrary.org/obo/CHEBI_132893 fangchinoline http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether A bisbenzylisoquinoline alkaloid that is (1beta)- berbaman which has been substituted by methyl groups at the 2 and 2' positions, by methoxy groups at the 6, 6', and 12 positions, and by a hydroxy group at position 7. Isolated from Stephania tetrandra, it has been found to possess neuroprotective and anti-tumour activity. http://purl.obolibrary.org/obo/CHEBI_132894 cassameridine http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone An oxoaporphine alkaloid that is 7H-dibenzo[de,g]quinolin-7-one which is substituted by methylenedioxy grups at the 1,2 and 9,10 positions. Compared with liriodenine, which lacks the 9,10-methylenedioxy group, cassameridine displays only moderate antifungal activity. http://purl.obolibrary.org/obo/CHEBI_132895 oxofangchirine http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether A bisbenzylisoquinoline alkaloid that is 1',2',3',4'-tetradehydroberbaman which has been substituted by a methyl group at position 2, methoxy groups at positions 6, 6', 7, and 12, and an oxo group at the 15' position. Isolated from Stephania tetrandra. http://purl.obolibrary.org/obo/CHEBI_132896 22108-99-2 http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/161379 http://purl.obolibrary.org/obo/CHEBI_132899 BETA-TERPINEOL http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/8748 http://purl.obolibrary.org/obo/CHEBI_132900 (+)-homalomenol A http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound A sesquiterpenoid that is perhydroindane which is substituted by a (2-methylprop-1-en-1-yl) group at position 1, methyl groups at positions 3a and 7, and hydroxy groups at positions 4 and 7 (the 1R,3aR,4R,7S,7aR stereoisomer). http://purl.obolibrary.org/obo/CHEBI_132901 (+)-homalomenol B http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound A sesquiterpenoid that is (+)-homalomenol A in which the double bond of the 2-methylpropen-1-yl group has migrated from the 1-2 position to the 2-3 position. http://purl.obolibrary.org/obo/CHEBI_132902 1,4,7-Eudesmanetriol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/101634632 http://purl.obolibrary.org/obo/CHEBI_132903 oplodiol http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol https://pubchem.ncbi.nlm.nih.gov/compound/12313756 http://purl.obolibrary.org/obo/CHEBI_132904 bullatantriol http://purl.obolibrary.org/obo/CHEBI_27136 triol A sesqiterpenoid that is octahydro-1H-indene which is substituted by a 2-hydroxy-2-methylpropyl group at position 1, methyl groups at positions 3a and 7, and hydroxy groups at positions 4 and 7 (the 1R,3aR,4R,7S,7aR stereoisomer). It has been isolated from various Homalomena species. http://purl.obolibrary.org/obo/CHEBI_132905 alpha-Cadinol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/10398656 http://purl.obolibrary.org/obo/CHEBI_132906 T-Muurolol http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/3084331 http://purl.obolibrary.org/obo/CHEBI_132907 Mucrolidin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity https://pubchem.ncbi.nlm.nih.gov/compound/14864716 http://purl.obolibrary.org/obo/CHEBI_132998 oxoaporphine alkaloid http://purl.obolibrary.org/obo/CHEBI_22750 benzylisoquinoline alkaloid Any benzylisoquinoline alkaloid that has a 7-keto-4H-dibenzo[de,g]quinoline skeleton. They are found in members of the Anonacea, Aracea, Hernandiaceae, Lauraceae, Magnoliaceae, Menispermaceae, Monimiaceae, Papaveraceae, and Ranunculaceae families. http://purl.obolibrary.org/obo/CHEBI_133018 diterpene triepoxide http://purl.obolibrary.org/obo/CHEBI_32955 epoxide A diterpenoid compound that contains three epoxide groups. http://purl.obolibrary.org/obo/CHEBI_133131 spiro-epoxide http://purl.obolibrary.org/obo/CHEBI_37948 oxaspiro compound An oxaspiro compound in which a carbon atom of an epoxide ring is the only common member of two rings. http://purl.obolibrary.org/obo/CHEBI_133135 chromenochromene http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound Any organic heteroolycyclic compound whose skeleton two ortho-fused chromene rings, and their derivatives. http://purl.obolibrary.org/obo/CHEBI_133173 2-undecenal http://purl.obolibrary.org/obo/CHEBI_133150 undecenal An undecenal that has formula C11H20O. http://purl.obolibrary.org/obo/CHEBI_13643 glycol http://purl.obolibrary.org/obo/CHEBI_23824 diol A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. http://purl.obolibrary.org/obo/CHEBI_15366 acetic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A simple monocarboxylic acid containing two carbons. http://purl.obolibrary.org/obo/CHEBI_15741 succinic acid http://purl.obolibrary.org/obo/CHEBI_28383 alpha,omega-dicarboxylic acid An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle. http://purl.obolibrary.org/obo/CHEBI_15771 loganin http://purl.obolibrary.org/obo/CHEBI_38606 cyclopentapyran An iridoid monoterpenoid isolated from the plant species of the genus Cornus. http://purl.obolibrary.org/obo/CHEBI_15889 sterol http://purl.obolibrary.org/obo/CHEBI_36834 3-hydroxy steroid A 3-hydroxy steroid closely related to cholestan-3-ol. http://purl.obolibrary.org/obo/CHEBI_15940 nicotinic acid http://purl.obolibrary.org/obo/CHEBI_26420 pyridinemonocarboxylic acid A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. http://purl.obolibrary.org/obo/CHEBI_16449 alanine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2. http://purl.obolibrary.org/obo/CHEBI_16632 vanillate http://purl.obolibrary.org/obo/CHEBI_25388 monohydroxybenzoate A methoxybenzoate that is the conjugate base of vanillic acid. http://purl.obolibrary.org/obo/CHEBI_16761 ADP http://purl.obolibrary.org/obo/CHEBI_37038 purine ribonucleoside 5'-diphosphate A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase. http://purl.obolibrary.org/obo/CHEBI_16765 tryptamine http://purl.obolibrary.org/obo/CHEBI_64365 aralkylamino compound An aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position. http://purl.obolibrary.org/obo/CHEBI_16857 L-threonine http://purl.obolibrary.org/obo/CHEBI_26986 threonine An optically active form of threonine having L-configuration. http://purl.obolibrary.org/obo/CHEBI_16947 citrate(3-) http://purl.obolibrary.org/obo/CHEBI_27092 tricarboxylic acid trianion A tricarboxylic acid trianion, obtained by deprotonation of the three carboxy groups of citric acid. http://purl.obolibrary.org/obo/CHEBI_17002 cholesterol ester http://purl.obolibrary.org/obo/CHEBI_35915 sterol ester Cholesterol esterified at the 3-hydroxy group. http://purl.obolibrary.org/obo/CHEBI_17351 linoleic acid http://purl.obolibrary.org/obo/CHEBI_25627 octadecadienoic acid An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry. http://purl.obolibrary.org/obo/CHEBI_17558 quercitrin http://purl.obolibrary.org/obo/CHEBI_76424 quercetin O-glycoside A quercetin O-glycoside that is quercetin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage. http://purl.obolibrary.org/obo/CHEBI_17620 ferulic acid http://purl.obolibrary.org/obo/CHEBI_24031 ferulic acids A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. http://purl.obolibrary.org/obo/CHEBI_17965 isoorientin http://purl.obolibrary.org/obo/CHEBI_83280 flavone C-glycoside A flavone C-glycoside consisting of luteolin having a beta-D-glucosyl residue at the 6-position. http://purl.obolibrary.org/obo/CHEBI_18059 lipid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. http://purl.obolibrary.org/obo/CHEBI_18262 dodecanoate http://purl.obolibrary.org/obo/CHEBI_78119 fatty acid anion 12:0 A medium-chain fatty acid anion that is the conjugate base of dodecanoic acid (lauric acid); major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_18295 histamine http://purl.obolibrary.org/obo/CHEBI_64365 aralkylamino compound A member of the class of imidazoles that is 1H-imidazole substituted at position C-4 by a 2-aminoethyl group. http://purl.obolibrary.org/obo/CHEBI_18310 alkane http://purl.obolibrary.org/obo/CHEBI_33653 aliphatic compound An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms. http://purl.obolibrary.org/obo/CHEBI_22583 antifeedant http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance that prevents pests from feeding. http://purl.obolibrary.org/obo/CHEBI_22917 phytogenic insecticide http://purl.obolibrary.org/obo/CHEBI_24852 insecticide An insecticide compound naturally occurring in plants. http://purl.obolibrary.org/obo/CHEBI_23357 cofactor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). http://purl.obolibrary.org/obo/CHEBI_23446 cyclic monoterpene ketone http://purl.obolibrary.org/obo/CHEBI_25408 monoterpene ketone A cyclic terpene ketone in which the terpene specified is monoterpene. http://purl.obolibrary.org/obo/CHEBI_23628 deoxyhexose http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose Any C6 deoxy sugar having at least one hydroxy group replaced by hydrogen. http://purl.obolibrary.org/obo/CHEBI_23778 dihydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_24676 hydroxybenzoic acid Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives. http://purl.obolibrary.org/obo/CHEBI_23824 diol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols. http://purl.obolibrary.org/obo/CHEBI_24128 furanocoumarin http://purl.obolibrary.org/obo/CHEBI_39432 furochromene Any furochromene that consists of a furan ring fused with a coumarin. The fusion may occur in different ways in give several isomers. http://purl.obolibrary.org/obo/CHEBI_24675 hydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_22718 benzoates Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_24833 oxoacid http://purl.obolibrary.org/obo/CHEBI_24651 hydroxides A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/CHEBI_24852 insecticide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. http://purl.obolibrary.org/obo/CHEBI_25367 molecule http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity Any polyatomic entity that is an electrically neutral entity consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_25413 monounsaturated fatty acid http://purl.obolibrary.org/obo/CHEBI_27208 unsaturated fatty acid Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment. http://purl.obolibrary.org/obo/CHEBI_25491 nematicide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance used to destroy pests of the phylum Nematoda (roundworms). http://purl.obolibrary.org/obo/CHEBI_25495 neohesperidoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A glycoside containing alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranosyl residue as the sugar unit. http://purl.obolibrary.org/obo/CHEBI_25629 stearate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A fatty acid anion 18:0 that is the conjugate base of stearic acid. Stearates have a variety of uses in the pharmaceutical industry. http://purl.obolibrary.org/obo/CHEBI_25646 octanoate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A straight-chain saturated fatty acid anion that is the conjugate base of octanoic acid (caprylic acid); believed to block adipogenesis. http://purl.obolibrary.org/obo/CHEBI_2571 aliphatic alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol An alcohol derived from an aliphatic compound. http://purl.obolibrary.org/obo/CHEBI_2580 unsaturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety. http://purl.obolibrary.org/obo/CHEBI_25835 hexadecanoate ester http://purl.obolibrary.org/obo/CHEBI_35748 fatty acid ester A fatty acid ester obtained by condensation of the carboxy group of palmitic acid with a hydroxy group of an alcohol or phenol. http://purl.obolibrary.org/obo/CHEBI_26013 pheromone http://purl.obolibrary.org/obo/CHEBI_26645 semiochemical A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour. http://purl.obolibrary.org/obo/CHEBI_26125 phytosterols http://purl.obolibrary.org/obo/CHEBI_26124 phytosteroid Sterols similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond. http://purl.obolibrary.org/obo/CHEBI_26155 plant growth regulator http://purl.obolibrary.org/obo/CHEBI_39317 growth regulator A chemical, natural or artificial, that can affect the rate of growth of a plant. http://purl.obolibrary.org/obo/CHEBI_26607 saturated fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess. http://purl.obolibrary.org/obo/CHEBI_26645 semiochemical http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger A molecular messenger released by an organism that affects the behaviour within or between species. http://purl.obolibrary.org/obo/CHEBI_26876 terpineol http://purl.obolibrary.org/obo/CHEBI_25411 monoterpenols A family of monoterpenols that have a p-menthane skeleton containing one double bond and bearing a single hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_27026 toxin http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Poisonous substance produced by a biological organism such as a microbe, animal or plant. http://purl.obolibrary.org/obo/CHEBI_27116 trihydroxyflavone http://purl.obolibrary.org/obo/CHEBI_24698 hydroxyflavone Any hydroxyflavone carrying three hydroxy groups at unspecified positions. http://purl.obolibrary.org/obo/CHEBI_27283 very long-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid A fatty acid which has a chain length greater than C22. http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion http://purl.obolibrary.org/obo/CHEBI_51151 dipolar compound A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer). http://purl.obolibrary.org/obo/CHEBI_28093 borneol http://purl.obolibrary.org/obo/CHEBI_22912 bornane monoterpenoid A bornane monoterpenoid that is 1,7,7-trimethylbicyclo[2.2.1]heptane substituted by a hydroxy group at position 2. http://purl.obolibrary.org/obo/CHEBI_28484 isovaleric acid http://purl.obolibrary.org/obo/CHEBI_38653 methylbutyric acid A C5, branched-chain saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_28802 flavonols http://purl.obolibrary.org/obo/CHEBI_24698 hydroxyflavone Any hydroxyflavone in which is the ring hydrogen at position 3 of the heterocyclic ring is replaced by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_28817 dodecane http://purl.obolibrary.org/obo/CHEBI_18310 alkane A straight-chain alkane with 12 carbon atoms. It has been form the essential oils of various plants including Zingiber officinale (ginger). http://purl.obolibrary.org/obo/CHEBI_28837 octanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid. http://purl.obolibrary.org/obo/CHEBI_28857 (Z)-hex-3-en-1-ol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A primary alcohol that consists of (3Z)-hex-3-ene substituted by a hydroxy group at position 1. http://purl.obolibrary.org/obo/CHEBI_28973 strychnine http://purl.obolibrary.org/obo/CHEBI_65323 monoterpenoid indole alkaloid A monoterpenoid indole alkaloid that is strychnidine bearing a keto substituent at the 10-position. http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated. http://purl.obolibrary.org/obo/CHEBI_30089 acetate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. http://purl.obolibrary.org/obo/CHEBI_30200 kaempferol 3-O-beta-D-glucoside http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative A kaempferol O-glucoside in which a glucosyl residue is attached at position 3 of kaempferol via a beta-glycosidic linkage. http://purl.obolibrary.org/obo/CHEBI_30363 isobutane http://purl.obolibrary.org/obo/CHEBI_18310 alkane An alkane that is propane substituted by a methyl group at position 2. http://purl.obolibrary.org/obo/CHEBI_30623 oxalate(2-) http://purl.obolibrary.org/obo/CHEBI_132952 oxalate A dicarboxylic acid dianion obtained by deprotonation of both carboxy groups of oxalic acid. http://purl.obolibrary.org/obo/CHEBI_30745 phenylacetic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A monocarboxylic acid that is toluene in which one of the hydrogens of the methyl group has been replaced by a carboxy group. http://purl.obolibrary.org/obo/CHEBI_30776 hexanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C6, straight-chain saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_30805 dodecanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil. http://purl.obolibrary.org/obo/CHEBI_30813 decanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C10, straight-chain saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_31001 octacosanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C28, very long straight-chain, saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_3193 Brucine http://purl.obolibrary.org/obo/CHEBI_65323 monoterpenoid indole alkaloid A monoterpenoid indole alkaloid that has formula C23H26N2O4. http://purl.obolibrary.org/obo/CHEBI_32878 alkene http://purl.obolibrary.org/obo/CHEBI_33645 acyclic olefin An acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. Acyclic branched or unbranched hydrocarbons having more than one double bond are alkadienes, alkatrienes, etc. http://purl.obolibrary.org/obo/CHEBI_33184 long-chain fatty acyl-CoA http://purl.obolibrary.org/obo/CHEBI_37554 fatty acyl-CoA A fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any long-chain (C13 to C22) fatty acid. http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_24433 group Any substituent group or skeleton containing carbon. http://purl.obolibrary.org/obo/CHEBI_33854 aromatic alcohol http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring. http://purl.obolibrary.org/obo/CHEBI_33893 reagent http://purl.obolibrary.org/obo/CHEBI_33232 application A substance used in a chemical reaction to detect, measure, examine, or produce other substances. http://purl.obolibrary.org/obo/CHEBI_33916 aldopentose http://purl.obolibrary.org/obo/CHEBI_15693 aldose A pentose with a (potential) aldehyde group at one end. http://purl.obolibrary.org/obo/CHEBI_33992 (-)-catechin http://purl.obolibrary.org/obo/CHEBI_23053 catechin The (-)-enantiomer of catechin. http://purl.obolibrary.org/obo/CHEBI_35191 triterpene http://purl.obolibrary.org/obo/CHEBI_35186 terpene A C30 terpene. http://purl.obolibrary.org/obo/CHEBI_35222 inhibitor http://purl.obolibrary.org/obo/CHEBI_24432 biological role A substance that diminishes the rate of a chemical reaction. http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group. http://purl.obolibrary.org/obo/CHEBI_35284 ammonium betaine http://purl.obolibrary.org/obo/CHEBI_35281 onium betaine Any neutral molecule having charge-separated forms with a quaternary ammonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom. http://purl.obolibrary.org/obo/CHEBI_35291 all-trans-retinoate http://purl.obolibrary.org/obo/CHEBI_15036 retinoate A retinoate that is the conjugate base of all-trans-retinoic acid. http://purl.obolibrary.org/obo/CHEBI_35294 carbopolycyclic compound http://purl.obolibrary.org/obo/CHEBI_35295 homopolycyclic compound A polyclic compound in which all of the ring members are carbon atoms. http://purl.obolibrary.org/obo/CHEBI_35493 antipyretic http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever. http://purl.obolibrary.org/obo/CHEBI_35516 cholestane http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent A steroid fundamental parent that has formula C27H48. http://purl.obolibrary.org/obo/CHEBI_35526 hypoglycemic agent http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug which lowers the blood glucose level. http://purl.obolibrary.org/obo/CHEBI_35617 flavouring agent http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that is used to added improve the taste or odour of a food. http://purl.obolibrary.org/obo/CHEBI_35705 immunosuppressive agent http://purl.obolibrary.org/obo/CHEBI_50846 immunomodulator An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. http://purl.obolibrary.org/obo/CHEBI_35753 tricarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion Any anion of a tricarboxylic acid formed by deprotonation of at least one carboxy group. http://purl.obolibrary.org/obo/CHEBI_35783 bornane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A monoterpene that has formula C10H18. http://purl.obolibrary.org/obo/CHEBI_35856 lipoxygenase inhibitor http://purl.obolibrary.org/obo/CHEBI_76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. http://purl.obolibrary.org/obo/CHEBI_35911 aconitane http://purl.obolibrary.org/obo/CHEBI_38525 terpene alkaloid fundamental parent A terpene alkaloid fundamental parent that has formula C18H27N. http://purl.obolibrary.org/obo/CHEBI_35969 3-hydroxy monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_61355 3-hydroxy carboxylic acid A hydroxy monocarboxylic acid that has a hydroxy group beta to the carboxy group. http://purl.obolibrary.org/obo/CHEBI_35972 dihydroxy monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35868 hydroxy monocarboxylic acid Any hydroxy monocarboxylic acid carrying at least two hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_36062 3,4-dihydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_33566 catechols A dihydroxybenzoic acid in which the hydroxy groups are located at positions 3 and 4. http://purl.obolibrary.org/obo/CHEBI_36084 dihydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_24675 hydroxybenzoate A hydroxybenzoate that is the conjugate base of dihydroxybenzoic acid. http://purl.obolibrary.org/obo/CHEBI_36130 cyclic terpene ketone http://purl.obolibrary.org/obo/CHEBI_36132 alicyclic ketone An alicyclic ketone in which the carbocyclic ring structure forms part of a terpene skeleton. http://purl.obolibrary.org/obo/CHEBI_36141 quinone http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included). http://purl.obolibrary.org/obo/CHEBI_36335 trypanocidal drug http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. http://purl.obolibrary.org/obo/CHEBI_36587 organic oxo compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element. http://purl.obolibrary.org/obo/CHEBI_36836 3beta-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol A 3-hydroxy steroid in which the 3-hydroxy substituent is in the beta-position. http://purl.obolibrary.org/obo/CHEBI_36976 nucleotide http://purl.obolibrary.org/obo/CHEBI_25608 nucleoside phosphate A nucleotide is a nucleoside phosphate. It is a phosphate ester that has a nucleoside moiety and has at least one phosphate moiety attached to the C-5 carbon of the ribose or deoxyribose moiety. http://purl.obolibrary.org/obo/CHEBI_37407 cyclic ether http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any ether in which the oxygen atom forms part of a ring. http://purl.obolibrary.org/obo/CHEBI_37485 hydroxyanthraquinones http://purl.obolibrary.org/obo/CHEBI_22580 anthraquinone An anthraquinone substituted with one or more hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_37963 pyranone http://purl.obolibrary.org/obo/CHEBI_26407 pyrans Any of a class of cyclic chemical compounds that contain an unsaturated six-membered ring with one ring oxygen atom and an oxo substituent. http://purl.obolibrary.org/obo/CHEBI_38131 lactol http://purl.obolibrary.org/obo/CHEBI_5653 hemiacetal Cyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues. http://purl.obolibrary.org/obo/CHEBI_38161 chelator http://purl.obolibrary.org/obo/CHEBI_52214 ligand A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. http://purl.obolibrary.org/obo/CHEBI_38231 phytotoxin http://purl.obolibrary.org/obo/CHEBI_76924 plant metabolite Any toxin produced by a plant. http://purl.obolibrary.org/obo/CHEBI_38234 DNA polymerase inhibitor http://purl.obolibrary.org/obo/CHEBI_76815 EC 2.7.7.* (nucleotidyltransferase) inhibitor Any inhibitor of a DNA polymerase. http://purl.obolibrary.org/obo/CHEBI_38462 EC 3.1.1.7 (acetylcholinesterase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. http://purl.obolibrary.org/obo/CHEBI_38684 tetrahydroxyflavone http://purl.obolibrary.org/obo/CHEBI_24698 hydroxyflavone Any hydroxyflavone carrying four hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_38749 dihydroxyflavanone http://purl.obolibrary.org/obo/CHEBI_24697 hydroxyflavanone Any hydroxyflavanone carrying two hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_38751 triamine http://purl.obolibrary.org/obo/CHEBI_88061 polyamine Any polyamine that contained three amino groups. http://purl.obolibrary.org/obo/CHEBI_39417 branched-chain saturated fatty acid http://purl.obolibrary.org/obo/CHEBI_35819 branched-chain fatty acid Any saturated fatty acid with a carbon side-chain or isopropyl termination. http://purl.obolibrary.org/obo/CHEBI_42504 pentadecanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain, fifteen-carbon carboxylic acid with no heteroatoms; a long-chain of mainly ruminant origin. http://purl.obolibrary.org/obo/CHEBI_43619 icosane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight chain alkane composed of 20 carbon atoms. It has been isolated from the leaves of Agave attenuata. http://purl.obolibrary.org/obo/CHEBI_44369 duvoglustat http://purl.obolibrary.org/obo/CHEBI_72490 2-(hydroxymethyl)piperidine-3,4,5-triol An optically active form of 2-(hydroxymethyl)piperidine-3,4,5-triol having 2R,3R,4R,5S-configuration. http://purl.obolibrary.org/obo/CHEBI_45571 heptanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C7, straight-chain fatty acid that contributes to the odour of some rancid oils. Used in the preparation of esters for the fragrance industry, and as an additive in cigarettes. http://purl.obolibrary.org/obo/CHEBI_46722 carbonate ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any carbonate that is carbonic acid in which the hydrogens have been replaced by organyl groups. http://purl.obolibrary.org/obo/CHEBI_47622 acetate ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any carboxylic ester where the carboxylic acid component is acetic acid. http://purl.obolibrary.org/obo/CHEBI_47788 3-oxo steroid http://purl.obolibrary.org/obo/CHEBI_35789 oxo steroid Any oxo steroid where an oxo substituent is located at position 3. http://purl.obolibrary.org/obo/CHEBI_47790 furofuran http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Organic heterobicyclic compounds containing a two furan rings ortho-fused to each other. http://purl.obolibrary.org/obo/CHEBI_48356 protic solvent http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent A polar solvent that is capable of acting as a hydron (proton) donor. http://purl.obolibrary.org/obo/CHEBI_48578 radical scavenger http://purl.obolibrary.org/obo/CHEBI_22586 antioxidant A role played by a substance that can react readily with, and thereby eliminate, radicals. http://purl.obolibrary.org/obo/CHEBI_48705 agonist http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. http://purl.obolibrary.org/obo/CHEBI_49080 marmesin http://purl.obolibrary.org/obo/CHEBI_26369 psoralens A psoralen that has formula C14H14O4. http://purl.obolibrary.org/obo/CHEBI_49211 syringaresinol http://purl.obolibrary.org/obo/CHEBI_25036 lignan A lignan that is 7,9':7',9-diepoxylignane substituted by hydroxy groups at positions 4 and 4' and methoxy groups at positions 3, 3', 5 and 5' respectively. http://purl.obolibrary.org/obo/CHEBI_50018 glycosyloxyflavone http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A member of the class of flavones having one or more glycosyl residues attached at unspecified positions. http://purl.obolibrary.org/obo/CHEBI_50177 dermatologic drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug used to treat or prevent skin disorders or for the routine care of skin. http://purl.obolibrary.org/obo/CHEBI_50202 naringenin http://purl.obolibrary.org/obo/CHEBI_38739 trihydroxyflavanone A trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'. http://purl.obolibrary.org/obo/CHEBI_50266 prodrug http://purl.obolibrary.org/obo/CHEBI_23888 drug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. http://purl.obolibrary.org/obo/CHEBI_50427 platelet aggregation inhibitor http://purl.obolibrary.org/obo/CHEBI_50248 hematologic agent A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. http://purl.obolibrary.org/obo/CHEBI_50503 laxative http://purl.obolibrary.org/obo/CHEBI_23888 drug An agent that produces a soft formed stool, and relaxes and loosens the bowels, typically used over a protracted period, to relieve constipation. Compare with cathartic, which is a substance that accelerates defecation. A substances can be both a laxative and a cathartic. http://purl.obolibrary.org/obo/CHEBI_50525 phenolate anion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion arising from deprotonation of the OH function of a phenol compound. http://purl.obolibrary.org/obo/CHEBI_50563 iridoid monoterpenoid http://purl.obolibrary.org/obo/CHEBI_25409 monoterpenoid One of a class of monoterpenoids biosynthesized from isoprene and often intermediates in the biosynthesis of alkaloids. Iridoids usually consist of a cyclopentane ring fused to a six-membered oxygen heterocycle. http://purl.obolibrary.org/obo/CHEBI_50582 alkenyl alcohol http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound Any aliphatic alcohol in which the carbon chain contains one or more olefinic bonds. http://purl.obolibrary.org/obo/CHEBI_50733 nutraceutical http://purl.obolibrary.org/obo/CHEBI_23888 drug A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. http://purl.obolibrary.org/obo/CHEBI_51026 macrocycle http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclic compound containing nine or more atoms as part of the cyclic system. http://purl.obolibrary.org/obo/CHEBI_51688 enal http://purl.obolibrary.org/obo/CHEBI_51718 alpha,beta-unsaturated aldehyde An alpha,beta-unsaturated aldehyde of general formula R(1)R(2)C=CR(3)-CH=O in which the aldehydic C=O function is conjugated to a C=C double bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_51702 enoate ester http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound An alpha,beta-unsaturated carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_51737 alpha,beta-unsaturated carboxylic ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester A carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) or R(1)C#C-C(=O)OR(2) (R(2) =/= H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_51751 enamide http://purl.obolibrary.org/obo/CHEBI_51750 alpha,beta-unsaturated carboxylic acid amide An alpha,beta-unsaturated carboxylic acid amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) in which the amide C=O function is conjugated to a C=C double bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A biological role played by the molecular entity or part thereof within a biochemical context. http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical http://purl.obolibrary.org/obo/CHEBI_33232 application Any substance introduced into a living organism with therapeutic or diagnostic purpose. http://purl.obolibrary.org/obo/CHEBI_52424 EC 3.2.1.* (glycosidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76761 EC 3.2.* (glycosylase) inhibitor An EC 3.2.* (glycosylase) inhibitor that interferes with the action of any glycosidase (i.e. enzymes hydrolysing O- and S-glycosyl compounds, EC 3.2.1.*). http://purl.obolibrary.org/obo/CHEBI_52557 tetracyclic diterpenoid http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid with a tetracyclic skeleton. http://purl.obolibrary.org/obo/CHEBI_53339 olefinic fatty acid http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound Any fatty acid containing at least one C=C double bond. http://purl.obolibrary.org/obo/CHEBI_58342 acyl-CoA(4-) http://purl.obolibrary.org/obo/CHEBI_58946 acyl-CoA oxoanion An acyl-CoA oxoanion arising from deprotonation of the phosphate and diphosphate OH groups of any acyl-CoA; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58946 acyl-CoA oxoanion http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion Any acyl coenzyme A thioester in which one or more of the phosphate and/or diphosphate groups has been deprotonated. http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion in which there is no C-C unsaturation. http://purl.obolibrary.org/obo/CHEBI_59768 aliphatic aldehyde http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde An aldehyde derived from an aliphatic compound http://purl.obolibrary.org/obo/CHEBI_59769 acetal http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' =/= H). Mixed acetals have R'' and R''' groups which differ. http://purl.obolibrary.org/obo/CHEBI_59770 cyclic acetal http://purl.obolibrary.org/obo/CHEBI_59769 acetal An acetal in the molecule of which the acetal carbon and one or both oxygen atoms thereon are members of a ring. http://purl.obolibrary.org/obo/CHEBI_59845 3-hydroxy fatty acid http://purl.obolibrary.org/obo/CHEBI_35969 3-hydroxy monocarboxylic acid Any fatty acid with a hydroxy functional group in the beta- or 3-position. beta-Hydroxy fatty acids accumulate during cardiac hypoxia, and can also be used as chemical markers of bacterial endotoxins. http://purl.obolibrary.org/obo/CHEBI_59997 EC 1.14.18.1 (tyrosinase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76845 EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC 1.14.18.1, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals. http://purl.obolibrary.org/obo/CHEBI_60004 mixture http://purl.obolibrary.org/obo/CHEBI_59999 chemical substance A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind. http://purl.obolibrary.org/obo/CHEBI_60164 ionic polymer http://purl.obolibrary.org/obo/CHEBI_60027 polymer An ionic polymer is a polymer, composed of ionic macromolecules. http://purl.obolibrary.org/obo/CHEBI_60926 amino monosaccharide http://purl.obolibrary.org/obo/CHEBI_28963 amino sugar Any amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group. http://purl.obolibrary.org/obo/CHEBI_61120 nucleobase-containing molecular entity http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene Any compound that has a nucleobase as a part. http://purl.obolibrary.org/obo/CHEBI_61355 3-hydroxy carboxylic acid http://purl.obolibrary.org/obo/CHEBI_24669 hydroxy carboxylic acid Any hydroxy carboxylic acid which contains a hydroxy group located beta- to the carboxylic acid group. http://purl.obolibrary.org/obo/CHEBI_61469 polyanionic polymer http://purl.obolibrary.org/obo/CHEBI_60164 ionic polymer A polymer, composed of polyanion macromolecules. http://purl.obolibrary.org/obo/CHEBI_61697 fatty acid derivative http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity derived from a fatty acid. http://purl.obolibrary.org/obo/CHEBI_61699 (-)-alpha-gurjunene http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A carbotricyclic compound and sesquiterpene that is 1a,2,3,4,4a,5,6,7b-octahydro-1H-cyclopropa[e]azulene which is substituted by methyl groups at positions 1, 1, 4 and 7 (the 1aR,4R,4aR,7bS- diastereoisomer). It has been isolated from plant species like Anaphalis nubigena and Jatropha ribifolia. http://purl.obolibrary.org/obo/CHEBI_61870 monounsaturated fatty acid aldehyde http://purl.obolibrary.org/obo/CHEBI_35746 fatty aldehyde Any fatty aldehyde with one double or triple bond located at any position in the aliphatic chain. http://purl.obolibrary.org/obo/CHEBI_62488 signalling molecule http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell. http://purl.obolibrary.org/obo/CHEBI_62643 anionic phospholipid http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-). http://purl.obolibrary.org/obo/CHEBI_62732 aromatic ester http://purl.obolibrary.org/obo/CHEBI_35701 ester An ester where the ester linkage is bonded directly to an aromatic system. http://purl.obolibrary.org/obo/CHEBI_63165 ribonucleoside monophosphate oxoanion http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion An organophosphate oxoanion resulting from deprotonation of at least one of the acidic hydroxy groups from the phosphate moiety of a ribonucleoside monophosphate. http://purl.obolibrary.org/obo/CHEBI_63353 disaccharide derivative http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from a disaccharide. http://purl.obolibrary.org/obo/CHEBI_63436 carbohydrate acid derivative http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from a carbohydrate acid. http://purl.obolibrary.org/obo/CHEBI_63473 aromatic amino-acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion An aromatic amino acid whose alpha-carboxylic acid group is ionized (non-protonated). http://purl.obolibrary.org/obo/CHEBI_63551 carbohydrate acid derivative anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative. http://purl.obolibrary.org/obo/CHEBI_63944 macrocyclic lactone http://purl.obolibrary.org/obo/CHEBI_51026 macrocycle Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule. http://purl.obolibrary.org/obo/CHEBI_64571 NMDA receptor agonist http://purl.obolibrary.org/obo/CHEBI_50103 excitatory amino acid agonist An excitatory amino acid agonist which binds to NMDA receptors and triggers a response. http://purl.obolibrary.org/obo/CHEBI_64621 quercetin O-glucoside http://purl.obolibrary.org/obo/CHEBI_76424 quercetin O-glycoside A quercetin O-glycoside that is an O-glucosylated derivative of quercetin. http://purl.obolibrary.org/obo/CHEBI_64909 poison http://purl.obolibrary.org/obo/CHEBI_24432 biological role Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism. http://purl.obolibrary.org/obo/CHEBI_64947 anti-HIV-1 agent http://purl.obolibrary.org/obo/CHEBI_64946 anti-HIV agent An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus. http://purl.obolibrary.org/obo/CHEBI_65255 food preservative http://purl.obolibrary.org/obo/CHEBI_64047 food additive Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes. http://purl.obolibrary.org/obo/CHEBI_65323 monoterpenoid indole alkaloid http://purl.obolibrary.org/obo/CHEBI_65321 terpenoid indole alkaloid A terpenoid indole alkaloid which is biosynthesised from L-tryptophan and diisoprenoid (usually secolaganin) building blocks. http://purl.obolibrary.org/obo/CHEBI_65331 alkyl caffeate ester http://purl.obolibrary.org/obo/CHEBI_36087 cinnamate ester A cinnamate ester obtained by formal condensation of caffeic acid with any alkyl alcohol. http://purl.obolibrary.org/obo/CHEBI_6570 lupeol http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol A pentacyclic triterpenoid that is lupane in which the hydrogen at the 3beta position is substituted by a hydroxy group. It occurs in the skin of lupin seeds, as well as in the latex of fig trees and of rubber plants. It is also found in many edible fruits and vegetables. http://purl.obolibrary.org/obo/CHEBI_6695 (+)-marmesin http://purl.obolibrary.org/obo/CHEBI_49080 marmesin A marmesin that has formula C14H14O4. http://purl.obolibrary.org/obo/CHEBI_6698 (-)-matairesinol http://purl.obolibrary.org/obo/CHEBI_37581 gamma-lactone A lignan that is gamma-butyrolactone in which the 3 and 4 positions are substituted by 4-hydroxy-3-methoxybenzyl groups (the 3R,4R-diastereomer). http://purl.obolibrary.org/obo/CHEBI_67232 EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_52424 EC 3.2.1.* (glycosidase) inhibitor An EC 3.2.1.* (glycosidase) inhibitor that inhibits the action of sucrose oligo-1,6-glucosidase (EC 3.2.1.10). http://purl.obolibrary.org/obo/CHEBI_67239 EC 3.2.1.20 (alpha-glucosidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_52424 EC 3.2.1.* (glycosidase) inhibitor An EC 3.2.1.* (glycosidase) inhibitor that interferes with the action of alpha-glucosidase (EC 3.2.1.20). http://purl.obolibrary.org/obo/CHEBI_68889 hydroxytyrosol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A member of the class of catechols that is benzene-1,2-diol substituted by a 2-hydroxyethyl group at position 4. Isolated from Olea europaea, it exhibits antioxidant and antineoplastic activities. http://purl.obolibrary.org/obo/CHEBI_69848 oppsit-4(15)-ene-1beta,11-diol http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid A sesquiterpenoid that has formula C15H26O2. http://purl.obolibrary.org/obo/CHEBI_70727 topoisomerase inhibitor http://purl.obolibrary.org/obo/CHEBI_76830 EC 5.99.1.* (miscellaneous isomerase) inhibitor An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA). http://purl.obolibrary.org/obo/CHEBI_70868 antileishmanial agent http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug An antiprotozoal drug used to treat or prevent infections caused by protozoan parasites that belong to the genus Leishmania. http://purl.obolibrary.org/obo/CHEBI_70994 hexacyclic triterpenoid http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound A triterpenoid that consists of a hexacyclic ring system. http://purl.obolibrary.org/obo/CHEBI_71037 extended flavonoid http://purl.obolibrary.org/obo/CHEBI_47916 flavonoid Any flavonoid with one or more rings fused on to the phenyl substituted benzopyran framework. http://purl.obolibrary.org/obo/CHEBI_71548 dihydroagarofuran sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid Any sesquiterpenoid with a dihydroagarofuran skeleton. http://purl.obolibrary.org/obo/CHEBI_71575 friedelane http://purl.obolibrary.org/obo/CHEBI_35191 triterpene A triterpene that is docosahydropicene substituted by 8 methyl groups at positions 2, 2, 4a, 6a, 8a, 9, 12b and 14a. http://purl.obolibrary.org/obo/CHEBI_72730 flavanone glycoside http://purl.obolibrary.org/obo/CHEBI_28863 flavanones A member of the class of flavanones having one or more glycosyl residues attached at unspecified positions. http://purl.obolibrary.org/obo/CHEBI_73216 EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*). http://purl.obolibrary.org/obo/CHEBI_73240 NF-kappaB inhibitor http://purl.obolibrary.org/obo/CHEBI_35222 inhibitor An inhibitor of NF-kappaB (nuclear factor kappa-light-chain-enhancer of activated B cells), a protein complex involved in the transcription of DNA. http://purl.obolibrary.org/obo/CHEBI_74518 anti-obesity agent http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Any substance which is used to reduce or control weight. http://purl.obolibrary.org/obo/CHEBI_74960 homoeriodictyol http://purl.obolibrary.org/obo/CHEBI_38739 trihydroxyflavanone A trihydroxyflavanone that consists of 3'-methoxyflavanone in which the three hydroxy substituents are located at positions 4', 5, and 7. http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite Any animal metabolite produced during a metabolic reaction in mammals. http://purl.obolibrary.org/obo/CHEBI_75769 B vitamin http://purl.obolibrary.org/obo/CHEBI_27314 water-soluble vitamin Any of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises vitamin B1, B2, B3, B5, B6, B7, B9, and B12. (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such.) http://purl.obolibrary.org/obo/CHEBI_76567 polyunsaturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_2580 unsaturated fatty acid anion Any unsaturated fatty acid anion containing more than one C-C unsaturated bond. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor http://purl.obolibrary.org/obo/CHEBI_76740 EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*). http://purl.obolibrary.org/obo/CHEBI_77636 fatty acyl-CoA(4-) http://purl.obolibrary.org/obo/CHEBI_58342 acyl-CoA(4-) An acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of any fatty acyl-CoA; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78206 fatty acid ethyl ester http://purl.obolibrary.org/obo/CHEBI_35748 fatty acid ester A fatty acid ester that is the carboxylic ester obtained by the formal condensation of a fatty acid with ethanol. http://purl.obolibrary.org/obo/CHEBI_78608 alpha-amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78884 4-terpineol http://purl.obolibrary.org/obo/CHEBI_26878 tertiary alcohol A terpineol that is 1-menthene carrying a hydroxy substituent at position 4. http://purl.obolibrary.org/obo/CHEBI_7889 Paeoniflorin http://purl.obolibrary.org/obo/CHEBI_61777 terpene glycoside A terpene glycoside that has formula C23H28O11. http://purl.obolibrary.org/obo/CHEBI_78954 (omega-1)-hydroxy fatty acid http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol A hydroxy fatty acid that is a straight-chain fatty acid in which one of the hydrogens attached to the carbon adjacent to the terminal methyl group (i.e. at the (omega-1) position) is replaced by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_8225 pinoresinol http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol A lignan that is tetrahydro-1H,3H-furo[3,4-c]furan substituted at positions 1 and 4 by 4-hydroxy-3-methoxyphenyl groups. http://purl.obolibrary.org/obo/CHEBI_82680 monounsaturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_2580 unsaturated fatty acid anion Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain. http://purl.obolibrary.org/obo/CHEBI_83039 crustacean metabolite http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill. http://purl.obolibrary.org/obo/CHEBI_83139 long-chain fatty acyl-CoA(4-) http://purl.obolibrary.org/obo/CHEBI_77636 fatty acyl-CoA(4-) A fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of any long-chain fatty acyl-CoA; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_83280 flavone C-glycoside http://purl.obolibrary.org/obo/CHEBI_20857 C-glycosyl compound Any C-glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a flavone skeleton, thus creating a C-C bond. http://purl.obolibrary.org/obo/CHEBI_84087 human urinary metabolite http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite Any metabolite (endogenous or exogenous) found in human urine samples. http://purl.obolibrary.org/obo/CHEBI_84497 (omega-1)-hydroxy fatty acid anion http://purl.obolibrary.org/obo/CHEBI_59835 hydroxy fatty acid anion A hydroxy fatty acid anion obtained by deprotonation of the carboxy group of any (omega-1)-hydroxy fatty acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_85348 11,12-saturated fatty acyl-CoA http://purl.obolibrary.org/obo/CHEBI_37554 fatty acyl-CoA Any fatty acyl-CoA in which the 11-12 bond of the fatty acyl group is saturated. http://purl.obolibrary.org/obo/CHEBI_86327 antifungal drug http://purl.obolibrary.org/obo/CHEBI_35718 antifungal agent Any antifungal agent used to prevent or treat fungal infections in humans or animals. http://purl.obolibrary.org/obo/CHEBI_20030 3-hexenal http://purl.obolibrary.org/obo/CHEBI_24578 hexenal A hexenal carrying an unsaturation at position 3. http://purl.obolibrary.org/obo/CHEBI_22211 aconitic acid http://purl.obolibrary.org/obo/CHEBI_27093 tricarboxylic acid A tricarboxylic acid that is prop-1-ene substituted by carboxy groups at positions 1, 2 and 3. http://purl.obolibrary.org/obo/CHEBI_22221 acyl group http://purl.obolibrary.org/obo/CHEBI_33247 organic group An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids. http://purl.obolibrary.org/obo/CHEBI_22290 aldaric acid http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid Dicarboxylic acids formed from aldoses by replacement of both terminal groups (CHO and CH2OH) by carboxy groups. http://purl.obolibrary.org/obo/CHEBI_22323 alkyl group http://purl.obolibrary.org/obo/CHEBI_33248 hydrocarbyl group A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom. http://purl.obolibrary.org/obo/CHEBI_22527 aminopurine http://purl.obolibrary.org/obo/CHEBI_26401 purines Any purine having at least one amino substituent. http://purl.obolibrary.org/obo/CHEBI_22563 anion http://purl.obolibrary.org/obo/CHEBI_24870 ion A monoatomic or polyatomic species having one or more elementary charges of the electron. http://purl.obolibrary.org/obo/CHEBI_22645 arenecarboxamide http://purl.obolibrary.org/obo/CHEBI_62733 aromatic amide A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system. http://purl.obolibrary.org/obo/CHEBI_22918 branched-chain amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid Any amino acid in which the parent hydrocarbon chain has one or more alkyl substituents http://purl.obolibrary.org/obo/CHEBI_22984 calcium atom http://purl.obolibrary.org/obo/CHEBI_22313 alkaline earth metal atom An alkaline earth metal atom that has formula Ca. http://purl.obolibrary.org/obo/CHEBI_23004 carbamoyl group http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid. http://purl.obolibrary.org/obo/CHEBI_23016 carbonates http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Organooxygen compounds that are salts or esters of carbonic acid, H2CO3. http://purl.obolibrary.org/obo/CHEBI_23042 carotene http://purl.obolibrary.org/obo/CHEBI_35193 tetraterpene Hydrocarbon carotenoids. http://purl.obolibrary.org/obo/CHEBI_23292 cis-3-hexenal http://purl.obolibrary.org/obo/CHEBI_20030 3-hexenal The cis-isomer of 3-hexenal. http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. http://purl.obolibrary.org/obo/CHEBI_23453 cycloalkane http://purl.obolibrary.org/obo/CHEBI_33664 monocyclic hydrocarbon Saturated monocyclic hydrocarbons (with or without side chains). http://purl.obolibrary.org/obo/CHEBI_23639 deoxy sugar http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate Any sugar having a hydroxy group replaced with a hydrogen atom. http://purl.obolibrary.org/obo/CHEBI_23677 diazole http://purl.obolibrary.org/obo/CHEBI_68452 azole An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring. http://purl.obolibrary.org/obo/CHEBI_2430 aconitine http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid that is 20-ethyl-3alpha,13,15alpha-trihydroxy-1alpha,6alpha,16beta-trimethoxy-4-(methoxymethyl)aconitane-8,14alpha-diol having acetate and benzoate groups at the 8- and 14-positions respectively. http://purl.obolibrary.org/obo/CHEBI_24397 glycophospholipid http://purl.obolibrary.org/obo/CHEBI_16247 phospholipid Any phospholipid that contain both phosphate and carbohydrate as integral structural components. http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/BFO_0000023 role A role played by the molecular entity or part thereof within a biological context. http://purl.obolibrary.org/obo/CHEBI_2452 Acutumidine http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid An alkaloid that has formula C18H22ClNO6. http://purl.obolibrary.org/obo/CHEBI_24532 organic heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_33832 organic cyclic compound A cyclic compound having as ring members atoms of carbon and at least of one other element. http://purl.obolibrary.org/obo/CHEBI_24548 hexadecenoic acid http://purl.obolibrary.org/obo/CHEBI_59202 straight-chain fatty acid A C16 straight-chain monounsaturated fatty acid having one C=C double bond. http://purl.obolibrary.org/obo/CHEBI_24578 hexenal http://purl.obolibrary.org/obo/CHEBI_61870 monounsaturated fatty acid aldehyde A monounsaturated fatty acid aldehyde that is hexene having an oxo group at position 1. http://purl.obolibrary.org/obo/CHEBI_24651 hydroxides http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)). http://purl.obolibrary.org/obo/CHEBI_24676 hydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_33853 phenols Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring. http://purl.obolibrary.org/obo/CHEBI_24697 hydroxyflavanone http://purl.obolibrary.org/obo/CHEBI_28863 flavanones A member of the class of flavanones that consists of flavanone with one or more hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_24698 hydroxyflavone http://purl.obolibrary.org/obo/CHEBI_24043 flavones Any flavone in which one or more ring hydrogens are replaced by hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_24835 inorganic molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity that contains no carbon. http://purl.obolibrary.org/obo/CHEBI_24850 insect attractant http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A chemical that lures insects to a trap, thereby removing them from crops, animals or stored products. http://purl.obolibrary.org/obo/CHEBI_24870 ion http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity having a net electric charge. http://purl.obolibrary.org/obo/CHEBI_25107 magnesium atom http://purl.obolibrary.org/obo/CHEBI_22313 alkaline earth metal atom An alkaline earth metal atom that has formula Mg. http://purl.obolibrary.org/obo/CHEBI_25240 methoxyflavanone http://purl.obolibrary.org/obo/CHEBI_28863 flavanones A member of the class of flavanones that consists of flavanone with one or more methoxy substituents. http://purl.obolibrary.org/obo/CHEBI_25241 methoxyflavone http://purl.obolibrary.org/obo/CHEBI_24043 flavones Any member of the class of flavones with at least one methoxy substituent. http://purl.obolibrary.org/obo/CHEBI_25408 monoterpene ketone http://purl.obolibrary.org/obo/CHEBI_26872 terpene ketone A terpene ketone derived from a monoterpene. http://purl.obolibrary.org/obo/CHEBI_25582 nonaprenol http://purl.obolibrary.org/obo/CHEBI_26199 polyprenol Any polyprenol composed of at least nine isoprene units. http://purl.obolibrary.org/obo/CHEBI_25634 octadecenoic acid http://purl.obolibrary.org/obo/CHEBI_53339 olefinic fatty acid Any member of the group of C18 monounsaturated fatty acids with the double bond located at any position in the chain. http://purl.obolibrary.org/obo/CHEBI_25639 octadienol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A primary alcohol that is octanol consisting of two double bonds at unspecified positions. http://purl.obolibrary.org/obo/CHEBI_25710 organophosphorus compound http://purl.obolibrary.org/obo/CHEBI_33285 heteroorganic entity An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters. http://purl.obolibrary.org/obo/CHEBI_25741 oxide http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity An oxide is a chemical compound of oxygen with other chemical elements. http://purl.obolibrary.org/obo/CHEBI_25805 oxygen atom http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen A chalcogen that has formula O. http://purl.obolibrary.org/obo/CHEBI_25901 pentose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose). http://purl.obolibrary.org/obo/CHEBI_25944 pesticide http://purl.obolibrary.org/obo/CHEBI_33232 application Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. http://purl.obolibrary.org/obo/CHEBI_25998 3-phenyllactic acid http://purl.obolibrary.org/obo/CHEBI_49302 2-hydroxy monocarboxylic acid A 2-hydroxy monocarboxylic acid that is lactic acid in which one of the methyl hydrogens is substituted by a phenyl group. http://purl.obolibrary.org/obo/CHEBI_26020 phosphate http://purl.obolibrary.org/obo/CHEBI_26079 phosphoric acid derivative Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom. http://purl.obolibrary.org/obo/CHEBI_26214 porphyrins http://purl.obolibrary.org/obo/CHEBI_36309 cyclic tetrapyrrole Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure. http://purl.obolibrary.org/obo/CHEBI_26216 potassium atom http://purl.obolibrary.org/obo/CHEBI_22314 alkali metal atom An alkali metal atom that has formula K. http://purl.obolibrary.org/obo/CHEBI_26395 purine nucleotide http://purl.obolibrary.org/obo/CHEBI_26401 purines Any nucleotide that has a purine nucleobase. http://purl.obolibrary.org/obo/CHEBI_26400 purine ribonucleotide http://purl.obolibrary.org/obo/CHEBI_26395 purine nucleotide Any ribonucleotide that has a purine nucleobase. http://purl.obolibrary.org/obo/CHEBI_26469 quaternary nitrogen compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen. http://purl.obolibrary.org/obo/CHEBI_26490 quinate http://purl.obolibrary.org/obo/CHEBI_36125 cyclitol carboxylic acid anion A cyclitol carboxylic acid anion that is conjugate base of quinic acid. http://purl.obolibrary.org/obo/CHEBI_26546 rhamnose http://purl.obolibrary.org/obo/CHEBI_33983 deoxymannose A deoxymannose sugar that is the 6-deoxy derivative of hexose. http://purl.obolibrary.org/obo/CHEBI_26605 saponin http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A glycoside that is a compound containing one or more hydrophilic glycoside moieties combined with a lipophilic triterpenoid or steroid derivative. Found in particular abundance in plant species. http://purl.obolibrary.org/obo/CHEBI_26718 solanesol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A nonaprenol that is hexatriaconta-2,6,10,14,18,22,26,30,34-nonaen-1-ol substituted by 9 methyl groups at positions 3, 7, 11, 15, 19, 23, 27, 31 and 35 (the all-trans0stereoisomer). http://purl.obolibrary.org/obo/CHEBI_26806 succinate http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of succinic acid. http://purl.obolibrary.org/obo/CHEBI_26872 terpene ketone http://purl.obolibrary.org/obo/CHEBI_17087 ketone Any terpenoid which contains a keto group. http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid http://purl.obolibrary.org/obo/CHEBI_24913 isoprenoid Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group. http://purl.obolibrary.org/obo/CHEBI_26932 tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_38077 polypyrrole A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. http://purl.obolibrary.org/obo/CHEBI_26935 tetraterpenoid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid Any terpenoid derived from a tetraterpene. The term includes compounds in which the C40 skeleton of the parent tetraterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). http://purl.obolibrary.org/obo/CHEBI_27325 xanthophyll http://purl.obolibrary.org/obo/CHEBI_23044 carotenoid A subclass of carotenoids consisting of the oxygenated carotenes. http://purl.obolibrary.org/obo/CHEBI_27560 boron atom http://purl.obolibrary.org/obo/CHEBI_33317 boron group element atom A boron group element atom that has formula B. http://purl.obolibrary.org/obo/CHEBI_27561 oxirane http://purl.obolibrary.org/obo/CHEBI_36389 saturated organic heteromonocyclic parent A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. http://purl.obolibrary.org/obo/CHEBI_27568 selenium atom http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen A chalcogen that has formula Se. http://purl.obolibrary.org/obo/CHEBI_27573 silicon atom http://purl.obolibrary.org/obo/CHEBI_33306 carbon group element atom A carbon group element atom that has formula Si. http://purl.obolibrary.org/obo/CHEBI_27589 procyanidin B4 http://purl.obolibrary.org/obo/CHEBI_72010 hydroxyflavan A proanthocyanidin obtained by the condensation of (-)-epicatechin and (+)-catechin units. http://purl.obolibrary.org/obo/CHEBI_27594 carbon atom http://purl.obolibrary.org/obo/CHEBI_33306 carbon group element atom A carbon group element atom that has formula C. http://purl.obolibrary.org/obo/CHEBI_27693 sitosterol http://purl.obolibrary.org/obo/CHEBI_35348 3beta-sterol A phytosterols that is stigmast-5-ene substituted by a beta-hydroxy group at position 3. http://purl.obolibrary.org/obo/CHEBI_27794 isoferulic acid http://purl.obolibrary.org/obo/CHEBI_24031 ferulic acids A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 4 and 3 respectively on the phenyl ring. http://purl.obolibrary.org/obo/CHEBI_28066 gentiobiose http://purl.obolibrary.org/obo/CHEBI_24405 glycosylglucose A glycosylglucose consisting of two D-glucopyranose units connected by a beta-(1->6)-linkage. http://purl.obolibrary.org/obo/CHEBI_28088 genistein http://purl.obolibrary.org/obo/CHEBI_55465 7-hydroxyisoflavones 7-Hydroxyisoflavone with additional hydroxy groups at positions 5 and 4'. It is a phytoestrogenic isoflavone with antioxidant properties. http://purl.obolibrary.org/obo/CHEBI_28179 benzamide http://purl.obolibrary.org/obo/CHEBI_22702 benzamides An aromatic amide that consists of benzene bearing a single carboxamido substituent. The parent of the class of benzamides. http://purl.obolibrary.org/obo/CHEBI_28230 hesperetin http://purl.obolibrary.org/obo/CHEBI_48024 3'-hydroxyflavanones A trihydroxyflavanone having the three hydroxy gropus located at the 3'-, 5- and 7-positions and an additional methoxy substituent at the 4'-position. http://purl.obolibrary.org/obo/CHEBI_28412 eriodictyol http://purl.obolibrary.org/obo/CHEBI_48024 3'-hydroxyflavanones A tetrahydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 7, 3' and 4' respectively. http://purl.obolibrary.org/obo/CHEBI_28527 rutin http://purl.obolibrary.org/obo/CHEBI_26587 rutinoside A rutinoside that is quercetin with the hydroxy group at position C-3 substituted with glucose and rhamnose sugar groups. http://purl.obolibrary.org/obo/CHEBI_28623 campesterol http://purl.obolibrary.org/obo/CHEBI_35348 3beta-sterol A phytosterol that has formula C28H48O. http://purl.obolibrary.org/obo/CHEBI_28659 phosphorus atom http://purl.obolibrary.org/obo/CHEBI_33300 pnictogen A pnictogen that has formula P. http://purl.obolibrary.org/obo/CHEBI_28685 molybdenum atom http://purl.obolibrary.org/obo/CHEBI_33350 chromium group element atom A chromium group element atom that has formula Mo. http://purl.obolibrary.org/obo/CHEBI_28694 copper atom http://purl.obolibrary.org/obo/CHEBI_33366 copper group element atom A copper group element atom that has formula Cu. http://purl.obolibrary.org/obo/CHEBI_28777 liquiritigenin http://purl.obolibrary.org/obo/CHEBI_38749 dihydroxyflavanone A dihydroxyflavanone compound having the two hydroxy substituents at the 4'- and 7-positions. Isolated from the root of Glycyrrhizae uralensis, it is a selective agonist for oestrogen receptor beta. http://purl.obolibrary.org/obo/CHEBI_28813 sinapyl alcohol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A primary alcohol, being cinnamyl alcohol hydroxylated at C-4 and methoxylated at C-3 and -5. http://purl.obolibrary.org/obo/CHEBI_28819 naringin http://purl.obolibrary.org/obo/CHEBI_63353 disaccharide derivative A disaccharide derivative that is (S)-naringenin substituted by a 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. http://purl.obolibrary.org/obo/CHEBI_28824 stigmasterol http://purl.obolibrary.org/obo/CHEBI_35348 3beta-sterol A 3beta-sterol that consists of 3beta-hydroxystigmastane having double bonds at the 5,6- and 22,23-positions. http://purl.obolibrary.org/obo/CHEBI_28897 pentadecane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight-chain alkane with 15 carbon atoms. It is a component of volatile oils isolated from plants species like Scandix balansae. http://purl.obolibrary.org/obo/CHEBI_28906 protoanemonin http://purl.obolibrary.org/obo/CHEBI_50523 butenolide A butenolide that has formula C5H4O2. http://purl.obolibrary.org/obo/CHEBI_28963 amino sugar http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups. http://purl.obolibrary.org/obo/CHEBI_29005 cyclohexane http://purl.obolibrary.org/obo/CHEBI_23453 cycloalkane An alicyclic hydrocarbon comprising a ring of six carbon atoms; the cyclic form of hexane, used as a raw material in the manufacture of nylon. http://purl.obolibrary.org/obo/CHEBI_29035 manganese(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation A divalent metal cation in which the metal is manganese. http://purl.obolibrary.org/obo/CHEBI_29036 copper(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation An ion of copper carrying a double positive charge. http://purl.obolibrary.org/obo/CHEBI_29103 potassium(1+) http://purl.obolibrary.org/obo/CHEBI_37247 elemental potassium A monoatomic monocation obtained from potassium. http://purl.obolibrary.org/obo/CHEBI_29108 calcium(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation A calcium cation that has formula Ca. http://purl.obolibrary.org/obo/CHEBI_29452 nerol http://purl.obolibrary.org/obo/CHEBI_24221 3,7-dimethylocta-2,6-dien-1-ol The (2Z)-stereoisomer of 3,7-dimethylocta-2,6-dien-1-ol. It has been isolated from the essential oils from plants like lemon grass. http://purl.obolibrary.org/obo/CHEBI_32362 heptanoate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A medium-chain fatty acid anion that is the conjugate base of heptanoic acid; shown in myocardial ischaemia/reperfusion studies to increase levels of C4 Kreb's cycle intermediates. http://purl.obolibrary.org/obo/CHEBI_32627 leucinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that is the conjugate base of leucine, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32628 leucinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that is the conjugate acid of leucine, arising from protonation of the amino group. http://purl.obolibrary.org/obo/CHEBI_32871 prolinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32872 prolinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group. http://purl.obolibrary.org/obo/CHEBI_32879 propane http://purl.obolibrary.org/obo/CHEBI_18310 alkane An alkane that has formula C3H8. http://purl.obolibrary.org/obo/CHEBI_32892 nonane http://purl.obolibrary.org/obo/CHEBI_18310 alkane A straight chain alkane composed of 9 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_32988 amide http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/CHEBI_33232 application http://purl.obolibrary.org/obo/BFO_0000023 role Intended use of the molecular entity or part thereof by humans. http://purl.obolibrary.org/obo/CHEBI_33238 monoatomic entity http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity A monoatomic entity is a molecular entity consisting of a single atom. http://purl.obolibrary.org/obo/CHEBI_33240 coordination entity http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands). http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_37175 organic hydride An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system. http://purl.obolibrary.org/obo/CHEBI_33248 hydrocarbyl group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group A univalent group formed by removing a hydrogen atom from a hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A chemical entity constituting the smallest component of an element having the chemical properties of the element. http://purl.obolibrary.org/obo/CHEBI_33253 nucleon http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle Heavy nuclear particle: proton or neutron. http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity all atoms of which have the same atomic number. http://purl.obolibrary.org/obo/CHEBI_33285 heteroorganic entity http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms. http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity A molecular entity containing one or more atoms of an alkali metal. http://purl.obolibrary.org/obo/CHEBI_33299 alkaline earth molecular entity http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal. http://purl.obolibrary.org/obo/CHEBI_33300 pnictogen http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth. http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity A p-block molecular entity containing any pnictogen. http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom Any p-block element belonging to the group 16 family of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity Any p-block molecular entity containing a chalcogen. http://purl.obolibrary.org/obo/CHEBI_33318 main group element atom http://purl.obolibrary.org/obo/CHEBI_33250 atom An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33452 benzylic group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group Arylmethyl groups and derivatives formed by substitution: ArCR2-. http://purl.obolibrary.org/obo/CHEBI_33521 metal atom http://purl.obolibrary.org/obo/CHEBI_33250 atom An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity. http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_33318 main group element atom Any main group element atom belonging to the p-block of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33563 glycolipid http://purl.obolibrary.org/obo/CHEBI_35740 liposaccharide Any member of class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar part acylated by one or more fatty acids and the glycerol part may be absent. http://purl.obolibrary.org/obo/CHEBI_33598 carbocyclic compound http://purl.obolibrary.org/obo/CHEBI_33597 homocyclic compound A homocyclic compound in which all of the ring members are carbon atoms. http://purl.obolibrary.org/obo/CHEBI_33645 acyclic olefin http://purl.obolibrary.org/obo/CHEBI_33641 olefin Acyclic branched or unbranched hydrocarbons having one or more carbon-carbon double bond. http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity A main group molecular entity that contains one or more atoms of a p-block element. http://purl.obolibrary.org/obo/CHEBI_33832 organic cyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound Any organic molecule that consists of atoms connected in the form of a ring. http://purl.obolibrary.org/obo/CHEBI_35193 tetraterpene http://purl.obolibrary.org/obo/CHEBI_35186 terpene A C40 terpene. http://purl.obolibrary.org/obo/CHEBI_35391 aspartate(1-) http://purl.obolibrary.org/obo/CHEBI_132943 aspartate An alpha-amino-acid anion that is the conjugate base of aspartic acid. http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion http://purl.obolibrary.org/obo/CHEBI_33273 polyatomic anion An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen. http://purl.obolibrary.org/obo/CHEBI_35512 ergostane http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent A steroid fundamental parent that has formula C28H50. http://purl.obolibrary.org/obo/CHEBI_35559 furan http://purl.obolibrary.org/obo/CHEBI_38179 monocyclic heteroarene A monocyclic heteroarene with a structure consisting of a 5-membered ring containing four carbons and one oxygen, with formula C4H4O. It is a toxic, flammable, low-boiling (31degreeC) colourless liquid. http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity Any molecular entity consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_36358 polyatomic ion http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity An ion consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_36513 cadinane http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A sesquiterpene consisting of decalin having two methyl substituents at the 1- and 6-positions, an isopropyl substituent at the 4-position and (1S,4S,4aS,6S,8aS)-configuration. http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_24870 ion A monoatomic or polyatomic species having one or more elementary charges of the proton. http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity An organochalcogen compound is a compound containing at least one carbon-chalcogen bond. http://purl.obolibrary.org/obo/CHEBI_37155 hydrogen butenedioate http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion A dicarboxylic acid monoanion that has formula C4H3O4. http://purl.obolibrary.org/obo/CHEBI_37206 hexol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A polyol that contains 6 hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_37554 fatty acyl-CoA http://purl.obolibrary.org/obo/CHEBI_17984 acyl-CoA An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any fatty acid. http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity A molecular entity consisting of two or more chemical elements. http://purl.obolibrary.org/obo/CHEBI_37838 carboacyl group http://purl.obolibrary.org/obo/CHEBI_22221 acyl group A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_38264 2-amino-3-methylpentanoic acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid A branched chain amino acid that consists of 3-methylpentanoic acid bearing an amino substituent at position 2. http://purl.obolibrary.org/obo/CHEBI_3830 camphene http://purl.obolibrary.org/obo/CHEBI_36785 carbobicyclic compound A monoterpene with a bicyclic skeleton that is bicyclo[2.2.1]heptane substituted by geminal methyl groups at position 2 and a methylidene group at position 3. It is a widespread natural product found in many essential oils. http://purl.obolibrary.org/obo/CHEBI_38632 membrane transport modulator http://purl.obolibrary.org/obo/CHEBI_52208 biophysical role Any agent that affects the transport of molecular entities across a biological membrane. http://purl.obolibrary.org/obo/CHEBI_38738 monomethoxyflavanone http://purl.obolibrary.org/obo/CHEBI_25240 methoxyflavanone Any methoxyflavanone that is flavanone substituted by a methoxy group. http://purl.obolibrary.org/obo/CHEBI_38739 trihydroxyflavanone http://purl.obolibrary.org/obo/CHEBI_24697 hydroxyflavanone A hydroxyflavanone carrying three hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_38834 benzofurochromene http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound An organic heteropolycyclic compound whose skeleton consists of a chromene ring fused onto a 1-benzofuran ring, together with their substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_39141 Bronsted acid http://purl.obolibrary.org/obo/CHEBI_37527 acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). http://purl.obolibrary.org/obo/CHEBI_39317 growth regulator http://purl.obolibrary.org/obo/CHEBI_24432 biological role Any chemical substance that inhibits the life-cycle of an organism. http://purl.obolibrary.org/obo/CHEBI_39745 dihydrogenphosphate http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated. http://purl.obolibrary.org/obo/CHEBI_412516 5-hydroxymethylfurfural http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A member of the class of furans that is furan which is substituted at positions 2 and 5 by formyl and hydroxymethyl substituents, respectively. Virtually absent from fresh foods, it is naturally generated in sugar-containing foods during storage, and especially by drying or cooking. It is the causative component in honey that affects the presystemic metabolism and pharmacokinetics of GZ in-vivo. http://purl.obolibrary.org/obo/CHEBI_41808 decane http://purl.obolibrary.org/obo/CHEBI_18310 alkane A straight-chain alkane with 10 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_45296 hexadecane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight-chain alkane with 16 carbon atoms. It is a component of essential oil isolated from long pepper. http://purl.obolibrary.org/obo/CHEBI_49212 (-)-syringaresinol http://purl.obolibrary.org/obo/CHEBI_49211 syringaresinol The (7beta,7'beta,8beta,8'beta)-stereoisomer of syringaresinol. http://purl.obolibrary.org/obo/CHEBI_49637 hydrogen atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom A s-block element atom that has formula 1.00794. http://purl.obolibrary.org/obo/CHEBI_49786 nickel(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation An ion of nickel carrying a double positive charge. http://purl.obolibrary.org/obo/CHEBI_50128 biflavonoid http://purl.obolibrary.org/obo/CHEBI_72720 flavonoid oligomer A flavonoid oligomer that is obtained by the oxidative coupling of at least two units of aryl-substituted benzopyran rings or its substituted derivatives, resulting in the two ring systems being joined together by a single atom or bond. http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid. http://purl.obolibrary.org/obo/CHEBI_51285 acenoquinone http://purl.obolibrary.org/obo/CHEBI_51269 acenes Quinones containing an acene fused ring system. http://purl.obolibrary.org/obo/CHEBI_51422 organodiyl group http://purl.obolibrary.org/obo/CHEBI_51446 organic divalent group Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s). http://purl.obolibrary.org/obo/CHEBI_59549 essential fatty acid http://purl.obolibrary.org/obo/CHEBI_26208 polyunsaturated fatty acid Any member of the sub-set of polyunsaturated fatty acid for which there is an absolute dietary requirement. http://purl.obolibrary.org/obo/CHEBI_59698 phosphoric acids http://purl.obolibrary.org/obo/CHEBI_33457 phosphorus oxoacid Compounds containing one or more phosphoric acid units. http://purl.obolibrary.org/obo/CHEBI_60248 nickel ion http://purl.obolibrary.org/obo/CHEBI_36914 inorganic ion A nickel atom having a net electric charge. http://purl.obolibrary.org/obo/CHEBI_60980 beta-glucoside http://purl.obolibrary.org/obo/CHEBI_24278 glucoside A glucoside in which the anomeric carbon of the glycosidic bond is in a beta configuration http://purl.obolibrary.org/obo/CHEBI_61078 purine nucleoside bisphosphate http://purl.obolibrary.org/obo/CHEBI_37123 nucleoside bisphosphate A nucleoside bisphosphate that has a purine nucleobase. http://purl.obolibrary.org/obo/CHEBI_61079 ribonucleoside bisphosphate http://purl.obolibrary.org/obo/CHEBI_37123 nucleoside bisphosphate A nucleoside bisphosphate where sugar of the nucleoside is ribose. http://purl.obolibrary.org/obo/CHEBI_61777 terpene glycoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A terpenoid in which one or more hydroxy functions are glycosylated. http://purl.obolibrary.org/obo/CHEBI_63161 glycosyl compound http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity. http://purl.obolibrary.org/obo/CHEBI_63471 branched-chain amino-acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion A branched-chain amino acid whose alpha-carboxylic acid group is ionized (not protonated). http://purl.obolibrary.org/obo/CHEBI_68452 azole http://purl.obolibrary.org/obo/CHEBI_38179 monocyclic heteroarene Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen. http://purl.obolibrary.org/obo/CHEBI_72720 flavonoid oligomer http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid A phenylpropanoid obtained by the coupling of two or more units of aryl-substituted benzopyran units and their substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_73992 alpha-L-rhamnopyranosyl-(1->2)-beta-D-glucopyranose http://purl.obolibrary.org/obo/CHEBI_36233 disaccharide A disaccharide consisting of alpha-L-rhamnose and beta-D-glucose linked via a 1->2 glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_76797 EC 2.5.1.18 (glutathione transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18). http://purl.obolibrary.org/obo/CHEBI_78095 hexadecenoate http://purl.obolibrary.org/obo/CHEBI_57560 long-chain fatty acid anion A long-chain unsaturated fatty acid anion that is the conjugate base of hexadecenoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78117 fatty acid anion 8:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 8 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78125 fatty acid anion 18:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 18 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78127 fatty acid anion 22:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 22 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_82663 elemental iron http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity An elemental molecular entity in which all of the atoms have atomic number 26. http://purl.obolibrary.org/obo/CHEBI_83811 proteinogenic amino acid derivative http://purl.obolibrary.org/obo/CHEBI_83821 amino acid derivative Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom. http://purl.obolibrary.org/obo/CHEBI_83820 non-proteinogenic amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid Any amino-acid that is not naturally encoded in the genetic code of any organism. http://purl.obolibrary.org/obo/CHEBI_84055 pentose phosphate http://purl.obolibrary.org/obo/CHEBI_33447 phospho sugar Any phospho sugar that is the phosphate derivative of pentose. http://purl.obolibrary.org/obo/CHEBI_88061 polyamine http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound Any organic amino compound that contains two or more amino groups. http://purl.obolibrary.org/obo/CHEBI_9023 santamarin http://purl.obolibrary.org/obo/CHEBI_37667 sesquiterpene lactone A sesquiterpene lactone of the eudesmanolide group. http://purl.obolibrary.org/obo/CHEBI_37619 L-galactopyranose http://purl.obolibrary.org/obo/CHEBI_37621 galactopyranose The L-enantiomer of galactopyranose. http://purl.obolibrary.org/obo/CHEBI_37621 galactopyranose http://purl.obolibrary.org/obo/CHEBI_28260 galactose The pyranose form of galactose. http://purl.obolibrary.org/obo/CHEBI_37627 L-glucopyranose http://purl.obolibrary.org/obo/CHEBI_37661 glucopyranose The L-enantiomer of glucopyranose. http://purl.obolibrary.org/obo/CHEBI_37659 oleanolic acid http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is olean-12-en-28-oic acid substituted by a beta-hydroxy group at position 3. http://purl.obolibrary.org/obo/CHEBI_38313 diazines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure). http://purl.obolibrary.org/obo/CHEBI_3882 Coriamyrtin http://purl.obolibrary.org/obo/CHEBI_37581 gamma-lactone A gamma-lactone that has formula C15H18O5. http://purl.obolibrary.org/obo/CHEBI_39142 Bronsted base http://purl.obolibrary.org/obo/CHEBI_22695 base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). http://purl.obolibrary.org/obo/CHEBI_39144 Lewis base http://purl.obolibrary.org/obo/CHEBI_22695 base A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct. http://purl.obolibrary.org/obo/CHEBI_39237 farnesene http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A sesquiterpene that is any of the four possible isomers of 3,7,11-trimethyl-1,3,6,10-dodecatetraene (alpha-farnesene) or of the two possible isomers of 7,11-dimethyl-3-methylene-1,6,10-dodecatriene. http://purl.obolibrary.org/obo/CHEBI_5653 hemiacetal http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A compound having the general formula RR'C(OH)OR'' (R'' =/= H). http://purl.obolibrary.org/obo/CHEBI_59948 columbianetin http://purl.obolibrary.org/obo/CHEBI_26878 tertiary alcohol The angular furanocoumarin analogue of the linear furanocoumarin marmesin. http://purl.obolibrary.org/obo/CHEBI_63962 Hsp90 inhibitor http://purl.obolibrary.org/obo/CHEBI_76939 EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor An EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor that blocks the action of heat shock protein 90. http://purl.obolibrary.org/obo/CHEBI_73398 indole skeleton http://purl.obolibrary.org/obo/CHEBI_73541 organic heterobicyclic ring A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring. http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*). http://purl.obolibrary.org/obo/CHEBI_76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76760 EC 3.1.* (ester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*). http://purl.obolibrary.org/obo/CHEBI_76815 EC 2.7.7.* (nucleotidyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*). http://purl.obolibrary.org/obo/CHEBI_76861 EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76730 EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*). http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor that interferes with one or more steps in a metabolic pathway. http://purl.obolibrary.org/obo/CHEBI_82828 oleanolate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of oleanolic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_83972 3-methyl fatty acid anion http://purl.obolibrary.org/obo/CHEBI_67013 methyl-branched fatty acid anion A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 3-methyl fatty acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_4867 Estragole http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound An olefinic compound that has formula C10H12O. http://purl.obolibrary.org/obo/CHEBI_49 (+)-Tetrandrine http://purl.obolibrary.org/obo/CHEBI_24922 isoquinolines A bisbenzylisoquinoline alkaloid that has formula C38H42N2O6. http://purl.obolibrary.org/obo/CHEBI_49083 (-)-marmesin http://purl.obolibrary.org/obo/CHEBI_49080 marmesin A marmesin that has formula C14H14O4. http://purl.obolibrary.org/obo/CHEBI_49156 (6S)-vomifoliol http://purl.obolibrary.org/obo/CHEBI_28258 vomifoliol A vomifoliol that has formula C13H20O3. http://purl.obolibrary.org/obo/CHEBI_49160 (6R,9S)-vomifoliol http://purl.obolibrary.org/obo/CHEBI_49161 (6R)-vomifoliol A (6R)-vomifoliol that has formula C13H20O3. http://purl.obolibrary.org/obo/CHEBI_49161 (6R)-vomifoliol http://purl.obolibrary.org/obo/CHEBI_28258 vomifoliol A vomifoliol that has formula C13H20O3. http://purl.obolibrary.org/obo/CHEBI_49249 beta-bisabolene http://purl.obolibrary.org/obo/CHEBI_49235 bisabolene A bisabolene that is cyclohexene substituted by a methyl group at position 1 and a 6-methylhepta-1,5-dien-2-yl group at position 4. http://purl.obolibrary.org/obo/CHEBI_4969 Fagomine http://purl.obolibrary.org/obo/CHEBI_26151 piperidines A piperidine that has formula C6H13NO3. http://purl.obolibrary.org/obo/CHEBI_50027 sabinene http://purl.obolibrary.org/obo/CHEBI_50030 thujene A thujene that is a bicyclic monoterpene isolated from the essential oils of various plant species. http://purl.obolibrary.org/obo/CHEBI_50030 thujene http://purl.obolibrary.org/obo/CHEBI_35187 monoterpene A monoterpene based on a thujane skeleton. http://purl.obolibrary.org/obo/CHEBI_50073 p-menthadiene http://purl.obolibrary.org/obo/CHEBI_35187 monoterpene A monoterpene that consists of an unsaturated p-menthane skeleton having two double bonds. http://purl.obolibrary.org/obo/CHEBI_50112 sex hormone http://purl.obolibrary.org/obo/CHEBI_24621 hormone Any hormone that is responsible for controlling sexual characteristics and reproductive function. http://purl.obolibrary.org/obo/CHEBI_50205 3,4-dihydroxybenzaldehyde http://purl.obolibrary.org/obo/CHEBI_50196 dihydroxybenzaldehyde A dihydroxybenzaldehyde that has formula C7H6O3. http://purl.obolibrary.org/obo/CHEBI_51061 hormone receptor modulator http://purl.obolibrary.org/obo/CHEBI_90710 receptor modulator A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A role played by the molecular entity or part thereof which causes the development of a pathological process. http://purl.obolibrary.org/obo/CHEBI_76760 EC 3.1.* (ester hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*). http://purl.obolibrary.org/obo/CHEBI_76838 EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*). http://purl.obolibrary.org/obo/CHEBI_76898 EC 1.14.14.1 (unspecific monooxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76838 EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1). http://purl.obolibrary.org/obo/CHEBI_88186 metal cation allergen http://purl.obolibrary.org/obo/CHEBI_25213 metal cation Any metal cation which causes the onset of an allergic reaction. http://purl.obolibrary.org/obo/CHEBI_90710 receptor modulator http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors. http://purl.obolibrary.org/obo/CHEBI_60798 excitatory amino acid antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist Any substance which inhibits the action of receptors for excitatory amino acids. http://purl.obolibrary.org/obo/CHEBI_6097 Kadsurenone http://purl.obolibrary.org/obo/CHEBI_35259 benzofurans A benzofuran that has formula C21H24O5. http://purl.obolibrary.org/obo/CHEBI_6113 karakoline http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound An organonitrogen heterocyclic compound that is aconitane bearing hydroxy groups at the 1alpha, 8, and 14alpha positions and substituted at on the nitrogen and at positions 4 and 16beta by ethyl, methyl, and methoxy groups, respectively. http://purl.obolibrary.org/obo/CHEBI_61293 adenyl nucleotide http://purl.obolibrary.org/obo/CHEBI_26395 purine nucleotide A nucleotide having adenine as the base. http://purl.obolibrary.org/obo/CHEBI_76730 EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH2 group of donors (EC 1.4.*.*). http://purl.obolibrary.org/obo/CHEBI_62513 gamma-eudesmol http://purl.obolibrary.org/obo/CHEBI_62508 eudesmane sesquiterpenoid A eudesmane sesquiterpenoid in which the eudesmane skeleton carries a hydroxy substituent at C-11 and has a double bond between C-4 and C-5. http://purl.obolibrary.org/obo/CHEBI_62854 beta-elemene http://purl.obolibrary.org/obo/CHEBI_48121 polyene A sesquiterpene that consists of cyclohexane bearing methyl and vinyl substituents at position 1 as well as two isopropenyl substituents at positions 2 and 4. http://purl.obolibrary.org/obo/CHEBI_63409 pentose derivative http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative A monosaccharide derivative that is formally obtained from a pentose. http://purl.obolibrary.org/obo/CHEBI_63797 3-hydroxy-4-methoxybenzoate http://purl.obolibrary.org/obo/CHEBI_25388 monohydroxybenzoate A monohydroxybenzoate that is the conjugate base of 3-hydroxy-4-methoxybenzoic acid, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_63798 3-hydroxy-4-methoxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_25389 monohydroxybenzoic acid A methoxybenzoic acid that is 4-methoxybenzoic acid bearing a hydroxy substituent at position 3. http://purl.obolibrary.org/obo/CHEBI_63921 2-butoxyethanol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A primary alcohol that is ethanol in which one of the methyl hydrogens is replaced by a butoxy group. A high-boiling (171degreeC) colourless liquid, it is used as a solvent for paints and inks, as well as in some dry cleaning solutions. http://purl.obolibrary.org/obo/CHEBI_63959 celastrol http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is 24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic acid bearing an oxo substituent at position 2, a hydroxy substituent at position 3 and two methyl groups at positions 9 and 13. An antioxidant and anti-inflammatory agent. Potently inhibits lipid peroxidation in mitochondria and inhibits TNF-alpha-induced NFkappaB activation. Also shown to inhibit topoisomerase II activity in vitro (IC50 = 7.41 muM). http://purl.obolibrary.org/obo/CHEBI_64106 protein kinase agonist http://purl.obolibrary.org/obo/CHEBI_48705 agonist An agonist that selectively binds to and activates a protein kinase receptor. http://purl.obolibrary.org/obo/CHEBI_76874 EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor http://purl.obolibrary.org/obo/CHEBI_76655 EC 2.1.* (C1-transferase) inhibitor An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*). http://purl.obolibrary.org/obo/CHEBI_76939 EC 3.6.4.10 (non-chaperonin molecular chaperone ATPase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76938 EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor An EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor that interferes with the action of a non-chaperonin molecular chaperone ATPase (EC 3.6.4.10). http://purl.obolibrary.org/obo/CHEBI_69542 (+)-isolariciresinol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A lignan that is 5,6,7,8-tetrahydronaphthalen-2-ol substituted by hydroxymethyl groups at positions 6 and 7, a methoxy group at position 3 and a 4-hydroxy-3-methoxyphenyl group at position 8. It has been isolated from the roots of Rubia yunnanensis. http://purl.obolibrary.org/obo/CHEBI_69581 Paeonol http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzene A methoxybenzene that has formula C9H10O3. http://purl.obolibrary.org/obo/CHEBI_69582 Paeoniflorigenone http://purl.obolibrary.org/obo/CHEBI_36054 benzoate ester A benzoate ester that has formula C17H18O6. http://purl.obolibrary.org/obo/CHEBI_69583 Benzoylpaeoniflorin http://purl.obolibrary.org/obo/CHEBI_61777 terpene glycoside A terpene glycoside that has formula C30H32O12. http://purl.obolibrary.org/obo/CHEBI_69584 Palbinone http://purl.obolibrary.org/obo/CHEBI_47786 16-oxo steroid A 16-oxo steroid that has formula C22H30O4. http://purl.obolibrary.org/obo/CHEBI_69657 kaempferol-3-rutinoside http://purl.obolibrary.org/obo/CHEBI_26587 rutinoside A kaempferol O-glucoside that is kaempferol attached to a rutinosyl [6-deoxy-alpha-L-mannosyl-(1->6)-beta-D-glucosyl] residue at position 3 via a glycosidic linkage. It has been isolated from the leaves of Solanum campaniforme. http://purl.obolibrary.org/obo/CHEBI_69669 Veraguensin http://purl.obolibrary.org/obo/CHEBI_25036 lignan A lignan that has formula C22H28O5. http://purl.obolibrary.org/obo/CHEBI_69670 5-Methoxygalbelgin http://purl.obolibrary.org/obo/CHEBI_25036 lignan A lignan that has formula C23H30O6. http://purl.obolibrary.org/obo/CHEBI_69686 pellitorine http://purl.obolibrary.org/obo/CHEBI_29348 fatty amide A fatty amide that has formula C14H25NO. http://purl.obolibrary.org/obo/CHEBI_69763 Euonymine http://purl.obolibrary.org/obo/CHEBI_37668 terpene lactone A terpene lactone that has formula C38H47NO18. http://purl.obolibrary.org/obo/CHEBI_69774 loliolide http://purl.obolibrary.org/obo/CHEBI_35259 benzofurans A benzofuran that has formula C11H16O3. http://purl.obolibrary.org/obo/CHEBI_69832 osthole http://purl.obolibrary.org/obo/CHEBI_86494 botanical anti-fungal agent A botanical anti-fungal agent that has formula C15H16O3. http://purl.obolibrary.org/obo/CHEBI_7005 morusin http://purl.obolibrary.org/obo/CHEBI_71037 extended flavonoid An extended flavonoid that is flavone substituted by hydroxy groups at positions 5, 2' and 4', a prenyl group at position 3 and a 2,2-dimethyl pyran group across positions 7 and 8. http://purl.obolibrary.org/obo/CHEBI_70253 4'-O-methylepigallocatechin http://purl.obolibrary.org/obo/CHEBI_23053 catechin A catechin that has formula C16H16O7. http://purl.obolibrary.org/obo/CHEBI_70682 Tormentic acid http://purl.obolibrary.org/obo/CHEBI_36615 triterpenoid A triterpenoid that has formula C30H48O5. http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor that inhibits the action of a transferase (EC 2.*) http://purl.obolibrary.org/obo/CHEBI_75092 morin http://purl.obolibrary.org/obo/CHEBI_52267 7-hydroxyflavonol A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5. http://purl.obolibrary.org/obo/CHEBI_76824 EC 6.4.1.* (carboxylase) inhibitor http://purl.obolibrary.org/obo/CHEBI_75604 EC 6.4.* (C-C bond-forming ligase) inhibitor An EC 6.4.* (C-C bond-forming ligase) inhibitor that interferes with the action of a carboxylating enzyme (EC 6.4.1.*). http://purl.obolibrary.org/obo/CHEBI_76830 EC 5.99.1.* (miscellaneous isomerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76697 EC 5.99.* (other isomerases) inhibitor An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class. http://purl.obolibrary.org/obo/CHEBI_78122 fatty acid anion 15:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 15 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_9429 tectorigenin http://purl.obolibrary.org/obo/CHEBI_55465 7-hydroxyisoflavones A methoxyisoflavone that is isoflavone substituted by a methoxy group at position 6 and hydroxy groups at positions 5, 7 and 4' respectively. http://purl.obolibrary.org/obo/CHEBI_71547 dihydroagarofuran http://purl.obolibrary.org/obo/CHEBI_35990 bridged compound A eudesmane sesquiterpenoid that is octahydro-2H-3,9a-methano-1-benzoxepine substituted by methyl groups at positions 2, 2, 5a and 9 (the 3R,5aS,9R,9aS stereoisomer). http://purl.obolibrary.org/obo/CHEBI_73541 organic heterobicyclic ring http://purl.obolibrary.org/obo/CHEBI_52845 cyclic organic group A bicyclic organic group that contains both carbon and hetero atoms. http://purl.obolibrary.org/obo/CHEBI_75381 EC 1.11.1.* (peroxidases) inhibitor http://purl.obolibrary.org/obo/CHEBI_76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*). http://purl.obolibrary.org/obo/CHEBI_7891 Paeonolide http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A glycoside that has formula C20H28O12. http://purl.obolibrary.org/obo/CHEBI_79 (-)-Arctigenin http://purl.obolibrary.org/obo/CHEBI_25036 lignan A lignan that has formula C21H24O6. http://purl.obolibrary.org/obo/CHEBI_7937 Parsonsine http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A macrolide that has formula C23H37NO7. http://purl.obolibrary.org/obo/CHEBI_7940 patchouli alcohol http://purl.obolibrary.org/obo/CHEBI_26878 tertiary alcohol A carbotricyclic compound and sesquiterpenoid tertiary alcohol that is tricyclo[5.3.1.0(3,8)]undecan-3-ol which is substituted at positions 2, 2, 6 and 8 by methyl groups (the 1R,3R,6S,7S,8S-diastereoisomer). http://purl.obolibrary.org/obo/CHEBI_80789 Acutumine http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid An alkaloid that has formula C19H24ClNO6. http://purl.obolibrary.org/obo/CHEBI_80791 Anemonin http://purl.obolibrary.org/obo/CHEBI_50523 butenolide A butenolide that has formula C10H8O4. http://purl.obolibrary.org/obo/CHEBI_80793 Arctiin http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A lignan that has formula C27H34O11. http://purl.obolibrary.org/obo/CHEBI_80819 Disinomenine http://purl.obolibrary.org/obo/CHEBI_25418 morphinane alkaloid A morphinane alkaloid that has formula C38H44N2O8. http://purl.obolibrary.org/obo/CHEBI_80850 Michelalbine http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid An alkaloid that has formula C17H15NO3. http://purl.obolibrary.org/obo/CHEBI_80907 Sweroside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A glycoside that has formula C16H22O9. http://purl.obolibrary.org/obo/CHEBI_80910 Tuduranine http://purl.obolibrary.org/obo/CHEBI_24921 isoquinoline alkaloid An isoquinoline alkaloid that has formula C18H19NO3. http://purl.obolibrary.org/obo/CHEBI_88081 fatty acid anion 23:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 23 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_81368 Sinactine http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid An alkaloid that has formula C20H21NO4. http://purl.obolibrary.org/obo/CHEBI_81369 Isosinomenine http://purl.obolibrary.org/obo/CHEBI_25418 morphinane alkaloid A morphinane alkaloid that has formula C19H23NO4. http://purl.obolibrary.org/obo/CHEBI_81371 Simiarenol http://purl.obolibrary.org/obo/CHEBI_36615 triterpenoid A triterpenoid that has formula C30H50O. http://purl.obolibrary.org/obo/CHEBI_82334 2,4-Hexadienal http://purl.obolibrary.org/obo/CHEBI_35746 fatty aldehyde A fatty aldehyde that has formula C6H8O. http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite http://purl.obolibrary.org/obo/CHEBI_83039 crustacean metabolite A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia http://purl.obolibrary.org/obo/CHEBI_88873 beta-Guaiene http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A sesquiterpene that has formula C15H24. http://purl.obolibrary.org/obo/CHEBI_9009 Salidroside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A glycoside that has formula C14H20O7. http://purl.obolibrary.org/obo/CHEBI_90709 nuclear receptor modulator http://purl.obolibrary.org/obo/CHEBI_90710 receptor modulator Any receptor modulator acting on nuclear receptors http://purl.obolibrary.org/obo/CHEBI_9163 Sinomenine http://purl.obolibrary.org/obo/CHEBI_25418 morphinane alkaloid A morphinane alkaloid that has formula C19H23NO4. http://purl.obolibrary.org/obo/OAE_0000002 medical intervention http://purl.obolibrary.org/obo/OBI_0000011 planned process medical intervention is a planned process that has the goal of diagnosing, preventing or relieving illness or injury. http://purl.obolibrary.org/obo/OAE_0000021 flushing AE http://purl.obolibrary.org/obo/OAE_0000423 skin discoloration AE a skin discoloration AE which has an outcome of flushing, a sudden reddening of the face, neck, or upper chest http://purl.obolibrary.org/obo/OAE_0000041 injury AE http://purl.obolibrary.org/obo/OAE_0002626 injury or procedural complication AE an injury and procedural complication AE which has an outcome of injury http://purl.obolibrary.org/obo/OAE_0000081 discomfort AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that resuls in an uncomfortable feeling. http://purl.obolibrary.org/obo/OAE_0000082 female reproductive system AE http://purl.obolibrary.org/obo/OAE_0000651 reproductive system AE a reproductive system AE that occurs on the female side. http://purl.obolibrary.org/obo/OAE_0000083 male reproductive system AE http://purl.obolibrary.org/obo/OAE_0000651 reproductive system AE a reproductive system AE that occurs on the male side. http://purl.obolibrary.org/obo/OAE_0000084 cardiac disorder AE http://purl.obolibrary.org/obo/OAE_0000493 cardiovascular AE a cardiovascular disorder AE that has a cardiac disorder outcome. http://purl.obolibrary.org/obo/OAE_0000115 intrinsic factor of adverse event http://purl.obolibrary.org/obo/BFO_0000023 role a role that is intrinsic to a patient and is associated with an adverse event. No causal effect between this factor and the adverse event is assumed. Examples include: age, race, organ dysfunction, disease, pregrancy, lactation, gender, and genetics. http://purl.obolibrary.org/obo/OAE_0000166 tremor AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE Tremor AE is a behavior and neurological AE that has an outcome of an involuntary trembling or quivering, and muscle contraction and relaxation. http://purl.obolibrary.org/obo/OAE_0000200 hair AE http://purl.obolibrary.org/obo/OAE_0000199 hair, skin or nail AE a hair, skin, and nail AE that occurs in hair. http://purl.obolibrary.org/obo/OAE_0000201 nail AE http://purl.obolibrary.org/obo/OAE_0000199 hair, skin or nail AE a hair, skin, and nail AE that occurs in nail. http://purl.obolibrary.org/obo/OAE_0000243 abdominal distension AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that results in a sensation of elevated abdominal pressure and volume http://purl.obolibrary.org/obo/OAE_0000268 agranulocytosis AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE a hematopoietic system AE that has an outcome of acute leukopenia, or lowered white blood cell count, most commonly of neutrophils causing neutropenia in circulating blood http://purl.obolibrary.org/obo/OAE_0000275 amenorrhoea AE http://purl.obolibrary.org/obo/OAE_0000082 female reproductive system AE a female reproductive system AE that is characterized by the absence of menstrual period in a woman of reproductive age http://purl.obolibrary.org/obo/OAE_0000302 balance disorder AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that has an outcome of a disturbance that causes an individual to feel unsteady, giddy, woozy, or have a sensation of movement, spinning, or floating. http://purl.obolibrary.org/obo/OAE_0000306 convulsion AE http://purl.obolibrary.org/obo/OAE_0000435 muscle AE convulsion AE is a muscle adverse event that results in a medical condition where body muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body http://purl.obolibrary.org/obo/OAE_0000328 kidney AE http://purl.obolibrary.org/obo/OAE_0000622 urinary system AE an adverse event that occurs in kidney. http://purl.obolibrary.org/obo/OAE_0000333 muscular weakness AE http://purl.obolibrary.org/obo/OAE_0000435 muscle AE a muscle AE that has an outcome of muscular weakness AE (i.e., lack of muscle strength). http://purl.obolibrary.org/obo/OAE_0000362 rash AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE a skin AE that shows the symptom of rash, i.e., an abnormal change in skin color, appearance, or texture. A rash may cause the skin to change color, itch, become warm, bumpy, dry, cracked or blistered, swell and may be painful. http://purl.obolibrary.org/obo/OAE_0000364 syndrome AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event An AE that has an outcome of syndrome. Syndrome is the association of several clinically recognizable features, signs (observed by a physician), symptoms (reported by the patient), phenomena or characteristics that often occur together, so that the presence of one feature alerts the physician to the presence of the others. http://purl.obolibrary.org/obo/OAE_0000374 pain AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that has an outcome of pain in a patient http://purl.obolibrary.org/obo/OAE_0000377 headache AE http://purl.obolibrary.org/obo/OAE_0000374 pain AE a pain AE that has an outcome of headache http://purl.obolibrary.org/obo/OAE_0000378 respiratory system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event an AE that occurs in respiratory system. http://purl.obolibrary.org/obo/OAE_0000381 abnormal blood pressure AE http://purl.obolibrary.org/obo/OAE_0000493 cardiovascular AE a cardiovascular disorder AE that has an outcome of abnormal blood pressure, representing altered tension of the blood within the systemic arteries http://purl.obolibrary.org/obo/OAE_0000388 dizziness AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that has an outcome of dizziness http://purl.obolibrary.org/obo/OAE_0000401 sweating AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE a skin adverse event that has an outcome of sweating http://purl.obolibrary.org/obo/OAE_0000411 asthma AE http://purl.obolibrary.org/obo/OAE_0000378 respiratory system AE a respiratory system AE which has an outcome of asthma http://purl.obolibrary.org/obo/OAE_0000414 back pain AE http://purl.obolibrary.org/obo/OAE_0000374 pain AE a pain AE that has an outcome of back pain http://purl.obolibrary.org/obo/OAE_0000418 neuropathy AE http://purl.obolibrary.org/obo/OAE_0000570 nervous system AE a nervous system AE that shows a damage to or disease affecting the nerves. http://purl.obolibrary.org/obo/OAE_0000426 speech disorder AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that has an outcome of disorder in speech http://purl.obolibrary.org/obo/OAE_0000430 nausea and vomiting AE http://purl.obolibrary.org/obo/OAE_0000554 abnormal digestion AE an abnormal digestion AE which has an outcome of nausea and vomiting http://purl.obolibrary.org/obo/OAE_0000435 muscle AE http://purl.obolibrary.org/obo/OAE_0000027 musculoskeletal or connective tissue AE a musculoskeletal system AE that occurs in muscle. http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event an AE that occurs in digestive system. http://purl.obolibrary.org/obo/OAE_0000440 facial paralysis AE http://purl.obolibrary.org/obo/OAE_0000539 paralysis AE a paralysis AE that has an outcome of paralysis in face http://purl.obolibrary.org/obo/OAE_0000449 erythema multiforme AE http://purl.obolibrary.org/obo/OAE_0000362 rash AE a rash AE which shows red, target-shaped or "bulls-eye" patches or sores on the skin. http://purl.obolibrary.org/obo/OAE_0000455 gastrointestinal disorder AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE which has an outcome of a gastrointestinal disorder http://purl.obolibrary.org/obo/OAE_0000464 liver function test abnormal AE http://purl.obolibrary.org/obo/OAE_0001694 liver related investigation result abnormal AE a liver related investigation result abnormal AE which shows an abnormal test result in a liver function test, indicating aberrant function of liver. http://purl.obolibrary.org/obo/OAE_0000471 palpitation AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that has an outcome of palpitation http://purl.obolibrary.org/obo/OAE_0000480 thrombocytopenic purpura AE http://purl.obolibrary.org/obo/OAE_0000487 purpura AE Thrombocytopenic purpura AE are purpura AE associated with a reduction in circulating blood platelets which can result from a variety of causes. http://purl.obolibrary.org/obo/OAE_0000482 amnesia AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that has an outcome of amnesia in a patient http://purl.obolibrary.org/obo/OAE_0000487 purpura AE http://purl.obolibrary.org/obo/OAE_0000423 skin discoloration AE a skin discoloration AE which has an outcome of purpura http://purl.obolibrary.org/obo/OAE_0000491 coma AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that has an outcome of coma http://purl.obolibrary.org/obo/OAE_0000495 urine abnormality AE http://purl.obolibrary.org/obo/OAE_0000622 urinary system AE a urinary system AE that has an outcome of urine abnormality AE http://purl.obolibrary.org/obo/OAE_0000499 increased salivation AE http://purl.obolibrary.org/obo/OAE_0000511 abnormal salivary gland physiology AE an abnormal salivary gland physiology AE which has an outcome of increased salivation, meaning greater than normal amounts of flowing saliva http://purl.obolibrary.org/obo/OAE_0000503 generalized spasm AE http://purl.obolibrary.org/obo/OAE_0000521 muscle spasm AE a muscle spasm AE which has an outcome of generalized spasm, which is an involuntary contraction of a muscle or group of muscles. Spasms may involve skeletal muscle (MUSCLE, SKELETAL) or smooth muscle (MUSCLE, SMOOTH). http://purl.obolibrary.org/obo/OAE_0000511 abnormal salivary gland physiology AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE which has an outcome of abnormal salivary gland physiology, which is any functional anomaly of any of the glands in the mouth that secrete saliva http://purl.obolibrary.org/obo/OAE_0000521 muscle spasm AE http://purl.obolibrary.org/obo/OAE_0000435 muscle AE a muscle adverse event which has an outcome of muscle spasm, which is an involuntary and often painful muscle contraction or cramps having a number of causes ranging from nutritional deficiency to serious nervous system conditions http://purl.obolibrary.org/obo/OAE_0000532 abnormal stool AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE which has an outcome of abnormal stool http://purl.obolibrary.org/obo/OAE_0000539 paralysis AE http://purl.obolibrary.org/obo/OAE_0000581 movement disorder AE a movement disorder AE that results in the loss of power of voluntary movement in a muscle through injury or disease of its nerve supply http://purl.obolibrary.org/obo/OAE_0000543 skin AE http://purl.obolibrary.org/obo/OAE_0000199 hair, skin or nail AE a hair, skin, and nail AE that occurs in skin. http://purl.obolibrary.org/obo/OAE_0000546 abnormal fluid regulation AE http://purl.obolibrary.org/obo/OAE_0000555 homeostasis AE a homeostasis AE which has an outcome of abnormal fluid regulation, which is any anomaly in the control of intracellular and/or extracellular fluid http://purl.obolibrary.org/obo/OAE_0000554 abnormal digestion AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE which has an outcome of abnormal digestion, which is an altered ability of the mechanical, chemical, and enzymatic processes of the body to convert ingested food into material suitable for assimilation for synthesis of tissues or liberation of energy http://purl.obolibrary.org/obo/OAE_0000555 homeostasis AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event an AE that occurs in the homeostasis system. http://purl.obolibrary.org/obo/OAE_0000557 inflammation AE http://purl.obolibrary.org/obo/OAE_0000476 immune system AE an immune system disorder AE that results in complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Inflammation is a protective attempt by the organism to remove the injurious stimuli as well as initiate the healing process for the tissue greater than expected response to injury, infection, or insult. http://purl.obolibrary.org/obo/OAE_0000564 respiratory system inflammation AE http://purl.obolibrary.org/obo/OAE_0000557 inflammation AE an inflammation AE which occurs in the respiratory system, which is reflected with the local accumulation of fluid, plasma proteins, and leukocytes in the respiratory system http://purl.obolibrary.org/obo/OAE_0000565 vasculitis AE http://purl.obolibrary.org/obo/OAE_0000557 inflammation AE an inflammation AE that has an outcome of vasculitis, which is an inflammation of a blood or lymph vessel http://purl.obolibrary.org/obo/OAE_0000571 abnormal respiration AE http://purl.obolibrary.org/obo/OAE_0000378 respiratory system AE a respiratory system AE which has an outcome of abnormal respiration, an anomaly in the movement of gases into and out of the lung http://purl.obolibrary.org/obo/OAE_0000573 deafness AE http://purl.obolibrary.org/obo/OAE_0000465 ear AE an ear disorder AE which has an outcome of deafness, which is an inability to hear http://purl.obolibrary.org/obo/OAE_0000574 gustatory system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event an adverse event that occurs in a gustatory system http://purl.obolibrary.org/obo/OAE_0000578 abnormal vision AE http://purl.obolibrary.org/obo/OAE_0000443 eye AE an eye disorder AE which has an outcome of abnormal vision, which is an inability or decreased ability to see http://purl.obolibrary.org/obo/OAE_0000579 seizure AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that shows a sudden surge of electrical activity in the brain. http://purl.obolibrary.org/obo/OAE_0000581 movement disorder AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that has an outcome of altered ability to coordinate voluntary movement or repetitive, compulsive movements http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event an adverse event which occurs in a hematopoietic system, which is any structural or developmental anomaly of the blood cells or the organs associated with the development and formation of blood cells http://purl.obolibrary.org/obo/OAE_0000589 mydriasis AE http://purl.obolibrary.org/obo/OAE_0000443 eye AE an eye disorder AE which has an outcome of mydriasis, which is dilation of one or both pupils regardless of light conditions http://purl.obolibrary.org/obo/OAE_0000592 opisthotonus AE http://purl.obolibrary.org/obo/OAE_0000581 movement disorder AE a muscle spasm AE that has an outcome of opisthotonus http://purl.obolibrary.org/obo/OAE_0000597 dysphagia AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a digestive system AE which has an outcome of dysphagia, which is a behavior and neurological AE that has an outcome of difficulty in swallowing food or liquid http://purl.obolibrary.org/obo/OAE_0000603 abnormal defecation AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE that has an outcome of abnormal defecation, an anomaly in the production and excretion of feces http://purl.obolibrary.org/obo/OAE_0000607 tinnitus AE http://purl.obolibrary.org/obo/OAE_0002129 hearing disorder AE an hearing disorder AE that shows a persistent sensation of buzzing, ringing, clicking, or other noises in the ear http://purl.obolibrary.org/obo/OAE_0000609 mouth mucosal ulceration AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE which has an outcome of mouth mucosal ulceration, which is lesions through the mucous membrane of the mouth, usually associated with loss of tissue http://purl.obolibrary.org/obo/OAE_0000622 urinary system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event an adverse event that has an outcome of urinary system AE is a functional anomaly of any of the organs involved in the production or excretion of urine http://purl.obolibrary.org/obo/OAE_0000624 abnormal body temperature AE http://purl.obolibrary.org/obo/OAE_0000555 homeostasis AE a homeostasis AE whic has an outcome of abnomal body temperature, which is a deviation in the level of heat natural to a living being http://purl.obolibrary.org/obo/OAE_0000630 ecchymosis AE http://purl.obolibrary.org/obo/OAE_0000427 hemorrhage AE a hemorrhage AE that has an outcome of ecchymosis http://purl.obolibrary.org/obo/OAE_0000651 reproductive system AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event reproductive system AE is an AE that occurs in the reproductive system. http://purl.obolibrary.org/obo/OAE_0000694 urine analysis result abnormal AE http://purl.obolibrary.org/obo/OAE_0001587 urinary system investigation result abnormal AE a urinary system investigation result abnormal AE that has an outcome of a urine analysis abnormality http://purl.obolibrary.org/obo/OAE_0000723 blood bilirubin level abnormal AE http://purl.obolibrary.org/obo/OAE_0001694 liver related investigation result abnormal AE a liver related investigation result abnormal AE that has an outcome of an abnormal amount of bilirubin in the blood http://purl.obolibrary.org/obo/OAE_0000724 blood bilirubin level increased AE http://purl.obolibrary.org/obo/OAE_0000723 blood bilirubin level abnormal AE a blood bilirubin level abnormal AE with an outcome of a increased amount of bilirubin, or a yellow breakdown product (broken down hemoglobin) of normal heme catabolism, in the blood http://purl.obolibrary.org/obo/OAE_0000753 bone marrow disorder AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE a hematopoietic system AE that has an outcome of disease in the bone marrow, the spongy tissue inside of some bones that contain stem cells that can develop into red blood cells, white blood cells or platelets http://purl.obolibrary.org/obo/OAE_0000784 cardiogenic shock AE http://purl.obolibrary.org/obo/OAE_0000551 hypotension AE a hypotension AE that has an outcome of the inability of the heart to supply enough blood to the organs of the body because of heart damage http://purl.obolibrary.org/obo/OAE_0000785 cardiomyopathy AE http://purl.obolibrary.org/obo/OAE_0000084 cardiac disorder AE a cardiovascular disorder AE that has an outcome of deterioration of the function of the myocardium, usually leads to heart failure http://purl.obolibrary.org/obo/OAE_0000842 coordination abnormal AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that results in a loss of coordination http://purl.obolibrary.org/obo/OAE_0000851 cutaneous vasculitis AE http://purl.obolibrary.org/obo/OAE_0000565 vasculitis AE an inflammation AE that has an outcome of inflamed blood vessels in the skin http://purl.obolibrary.org/obo/OAE_0000862 delirium AE http://purl.obolibrary.org/obo/OAE_0001797 psychiatric disorder AE a psychiatric disorder AE that results in a decline in level of cognitive function http://purl.obolibrary.org/obo/OAE_0000883 disturbance in attention AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that results in a loss of attention http://purl.obolibrary.org/obo/OAE_0000889 drug eruption AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE a skin AE that has an outcome of a range of adverse drugs reactions of the skin, most commonly rashes resembling measles http://purl.obolibrary.org/obo/OAE_0000909 electrocardiogram result abnormal AE http://purl.obolibrary.org/obo/OAE_0002612 cardiac function test abnormal AE a cardiac function test abnormal AE that has an outcome of abnormal electrical activity in the heart http://purl.obolibrary.org/obo/OAE_0000916 enteritis AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE with an outcome of inflammation in the intestine, especially the small intestine http://purl.obolibrary.org/obo/OAE_0000939 fall AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that has an outcome of patient falling http://purl.obolibrary.org/obo/OAE_0000956 fracture AE http://purl.obolibrary.org/obo/OAE_0000518 bone AE a bone disorder AE that has an outcome of complete or incomplete break in a bone resulting from the application of excessive force http://purl.obolibrary.org/obo/OAE_0000968 gastritis AE http://purl.obolibrary.org/obo/OAE_0001845 gastric disorder AE a gastric disorder AE that has an outcome of inflammation in the lining of the stomach http://purl.obolibrary.org/obo/OAE_0001026 hepatic failure AE http://purl.obolibrary.org/obo/OAE_0001135 liver AE a liver/biliary system AE that has an outcome of the inability of the liver to perform its normal synthetic and metabolic function http://purl.obolibrary.org/obo/OAE_0001035 hepatomegaly AE http://purl.obolibrary.org/obo/OAE_0001135 liver AE a liver/biliary system AE that has an outcome of swelling of the liver http://purl.obolibrary.org/obo/OAE_0001045 hyperhidrosis AE http://purl.obolibrary.org/obo/OAE_0000401 sweating AE a skin AE that results in excess perspiration http://purl.obolibrary.org/obo/OAE_0001129 leukopenia AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE a hematopoietic system AE that has an outcome of a lower than normal number of leukocytes, or nucleated cells of the myeloid or lymphoid lineages, found in blood or other tissue http://purl.obolibrary.org/obo/OAE_0001130 libido disorder AE http://purl.obolibrary.org/obo/OAE_0001797 psychiatric disorder AE a psychiatric disorder AE that results in a disorder in the patient's desire for sexual interaction http://purl.obolibrary.org/obo/OAE_0001201 myocarditis AE http://purl.obolibrary.org/obo/OAE_0000557 inflammation AE an inflammation AE that has an outcome of inflammation of the heart muscle http://purl.obolibrary.org/obo/OAE_0001209 nephrotic syndrome AE http://purl.obolibrary.org/obo/OAE_0000328 kidney AE a kidney disorder AE that has an outcome of a group of symptoms that include protein in the urine, low blood protein levels, high cholesterol levels, high triglyceride levels and swelling http://purl.obolibrary.org/obo/OAE_0001247 oral mucosa erosion AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE Digestive System AE that results in oral lesions http://purl.obolibrary.org/obo/OAE_0001275 pancytopenia AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE Hematopoietic System AE that results in a reduction in the amount of red and white blood cells and platelets in blood http://purl.obolibrary.org/obo/OAE_0001333 pseudomembranous colitis AE http://purl.obolibrary.org/obo/OAE_0000439 digestive system AE a digestive system AE that has an outcome of infection in the large intestine with an overgrowth of Clostridium difficile bacteria http://purl.obolibrary.org/obo/OAE_0001361 red blood cell count decreased AE http://purl.obolibrary.org/obo/OAE_0001711 red blood cell count abnormal AE a red blood cell count abnormal AE that has an outcome of a decrease in red blood cells http://purl.obolibrary.org/obo/OAE_0001397 skin hyperpigmentation AE http://purl.obolibrary.org/obo/OAE_0000423 skin discoloration AE a skin AE that has an outcome of darkening in an area of skin or nails caused by increased melanin http://purl.obolibrary.org/obo/OAE_0001403 sleep disorder AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that results in irregular sleep patterns http://purl.obolibrary.org/obo/OAE_0001433 suicide attempt AE http://purl.obolibrary.org/obo/OAE_0001797 psychiatric disorder AE a psychiatric disorder AE that results in attempted suicide http://purl.obolibrary.org/obo/OAE_0001448 thrombocytopenia AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE a hematopoietic system AE that has an outcome of decrease in platelets in the blood http://purl.obolibrary.org/obo/OAE_0001489 urinary retention AE http://purl.obolibrary.org/obo/OAE_0000622 urinary system AE Urinary system AE that results in an inability to urinate http://purl.obolibrary.org/obo/OAE_0001493 urine output decreased AE http://purl.obolibrary.org/obo/OAE_0000495 urine abnormality AE a urine abnormality AE that has an outcome of decreased urine output, less than 500 milliliters of urine in 24 hours http://purl.obolibrary.org/obo/OAE_0001527 multi-organ failure AE http://purl.obolibrary.org/obo/OAE_0000063 systematic AE A systematic adverse event that has an outcome of failure in mulitple organs http://purl.obolibrary.org/obo/OAE_0001570 cardiovascular investigation result abnormal AE http://purl.obolibrary.org/obo/OAE_0000628 investigation result abnormal AE an investigation result abnormal AE that involves an abnormal result of an investigation involving the cardiovascular system http://purl.obolibrary.org/obo/OAE_0001580 blood sodium increased http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality that has an increased level of sodium in the blood http://purl.obolibrary.org/obo/OAE_0001647 endocrine investigation result abnormal AE http://purl.obolibrary.org/obo/OAE_0000628 investigation result abnormal AE an investigation result abnormal AE that involves an abnormal result of an endocrine investigation http://purl.obolibrary.org/obo/OAE_0001665 red blood cell profile abnormal AE http://purl.obolibrary.org/obo/OAE_0001664 hematology investigation result abnormal AE a hematology investigation result abnormal AE that results in an abnormal red blood cell profile http://purl.obolibrary.org/obo/OAE_0001666 white blood cell profile abnormal AE http://purl.obolibrary.org/obo/OAE_0001664 hematology investigation result abnormal AE a hematology investigation result abnormal AE that is characterized by an abnormal white blood cell profile http://purl.obolibrary.org/obo/OAE_0001673 leukocyte cell number abnormal AE http://purl.obolibrary.org/obo/OAE_0001666 white blood cell profile abnormal AE a white blood cell profile abnormal AE that is characterized by an abnormal leukocyte cell number http://purl.obolibrary.org/obo/OAE_0001694 liver related investigation result abnormal AE http://purl.obolibrary.org/obo/OAE_0000628 investigation result abnormal AE an investigation result abnormal AE that is characterized by an abnormal liver related investigation result http://purl.obolibrary.org/obo/OAE_0001711 red blood cell count abnormal AE http://purl.obolibrary.org/obo/OAE_0001665 red blood cell profile abnormal AE a red blood cell profile abnormal AE that is characterized by an abnormal red blood cell count http://purl.obolibrary.org/obo/OAE_0001852 numbness AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that has an outcome of numbness, a loss of sensation of feeling in a part of the body. http://purl.obolibrary.org/obo/OAE_0001863 hemolytic anemia AE http://purl.obolibrary.org/obo/OAE_0000550 anemia AE Hemolytic anemia AE is an anemia AE associated with hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). Such an AE can be relatively harmless or life-threatening. http://purl.obolibrary.org/obo/OAE_0001880 heartburn AE http://purl.obolibrary.org/obo/OAE_0001845 gastric disorder AE Heartburn AE is a gastric disorder AE that also known as pyrosis, cardialgia, or acid indigestion. It's a burning sensation in the chest, just behind the breastbone or in the epigastrium, the upper central abdomen. The pain often rises in the chest and may radiate to the neck, throat, or angle of the jaw. http://purl.obolibrary.org/obo/OAE_0001885 mastauxe AE http://purl.obolibrary.org/obo/OAE_0000651 reproductive system AE Mastauxea AE is a reproductive system AE that shows enlargement of the breast. http://purl.obolibrary.org/obo/OAE_0001904 chromatosis AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE Chromatos AE is a skin AE shows that deposit of pigment in a normally unpigmented area or excessive pigmentation in a normally pigmented site. http://purl.obolibrary.org/obo/OAE_0001906 allergic rhinitis AE http://purl.obolibrary.org/obo/OAE_0000350 rhinitis AE Allergic rhinitis AE is a rhinitis AE that is an allergic inflammation of the nasal airways. It occurs when an allergen, such as pollen, dust, or animal dander (particles of shed skin and hair) is inhaled by an individual with a sensitized immune system. http://purl.obolibrary.org/obo/OAE_0001917 loose stools AE http://purl.obolibrary.org/obo/OAE_0000532 abnormal stool AE Loose stools AE is a abnormal stool AE that is usually a form of diarrhea and many conditions causing loose stool will be listed under diarrhea. It may also be related to watery stool (also within the spectrum of diarrhea). http://purl.obolibrary.org/obo/OAE_0001920 glossolalia AE http://purl.obolibrary.org/obo/OAE_0000426 speech disorder AE Glossolalia AE is a speech disorder AE that is the fluid vocalizing of speech-like syllables that lack any readily comprehended meaning. http://purl.obolibrary.org/obo/OAE_0001923 conduction block AE http://purl.obolibrary.org/obo/OAE_0000316 conduction system disorder AE Conduction block AE is a conduction system disorder AE that shows failure of impulse transmission at some point along a nerve fiber, although conduction along the segments proximal and distal to it are unaffected. http://purl.obolibrary.org/obo/OAE_0001924 photodermatitis AE http://purl.obolibrary.org/obo/OAE_0000086 dermatitis AE Photodermatitis AE is a dermatitis AE that referred to as sun poisoning or photoallergy, is a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. http://purl.obolibrary.org/obo/OAE_0001946 dysphoria AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE Dysphoria AE is a behavior and neurological AE that is a profound state of unease or dissatisfaction. In a psychiatric context, dysphoria may accompany depression, anxiety, or agitation. Common reactions to dysphoria include emotional distress or indifference. http://purl.obolibrary.org/obo/OAE_0002000 albuminuria AE http://purl.obolibrary.org/obo/OAE_0000495 urine abnormality AE Albuminuria AE is a urine abnormality AE that is a pathological condition wherein albumin is present in the urine. It is a type of proteinuria. http://purl.obolibrary.org/obo/OAE_0002003 contact dermatitis AE http://purl.obolibrary.org/obo/OAE_0000086 dermatitis AE Contact dermatitis AE is a dermatitis AE that is a type of skin inflammation.It results from exposure to allergens (allergic contact dermatitis) or irritants (irritant contact dermatitis). Phototoxic dermatitis occurs when the allergen or irritant is activated by sunlight. http://purl.obolibrary.org/obo/OAE_0002042 peripheral coldness AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE a sensory capability AE that has an outcome of peripheral coldness, or coldness of extremeties http://purl.obolibrary.org/obo/OAE_0002073 idiopathic thrombocytopenic purpura AE http://purl.obolibrary.org/obo/OAE_0000480 thrombocytopenic purpura AE a thrombocytopenic purpura AE with no known cause (idiopathic). Idiopathic thrombocytopenic purpura is a bleeding disorder in which the immune system destroys platelets, which are necesssary for normal blood clotting. Persons with this disorder have too few platelets in the blood. http://purl.obolibrary.org/obo/OAE_0002096 fear AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that has an outcome of fear, which is to be afraid and/or worried http://purl.obolibrary.org/obo/OAE_0002109 anaphylactic shock AE http://purl.obolibrary.org/obo/OAE_0000183 circulatory shock AE a circulatory AE that is a serious allergic reaction associated with systemic vasodilation that causes low blood pressure which is by definition 30% lower than the person's baseline or below standard values. http://purl.obolibrary.org/obo/OAE_0002113 acute intravascular hemolysis AE http://purl.obolibrary.org/obo/OAE_0000493 cardiovascular AE Acute intravascular hemolysis AE is a cardiovascular AE that has an outcome of disruption of red blood cells occurs while they are within blood vessels. http://purl.obolibrary.org/obo/OAE_0002121 skin redness AE http://purl.obolibrary.org/obo/OAE_0000645 erythema AE Skin redness AE is an erythema AE that is abnormal redness of the skin, often signaling a pathological condition, such as inflammation, infection, or sunburn. http://purl.obolibrary.org/obo/OAE_0002129 hearing disorder AE http://purl.obolibrary.org/obo/OAE_0000465 ear AE Hearing disorder AE is an ear disorder that shows impairment of the sense of hearing. http://purl.obolibrary.org/obo/OAE_0002135 increased defecation frequency AE http://purl.obolibrary.org/obo/OAE_0000532 abnormal stool AE Increased defecation frequency AE is a abnormal stool AE that shows defecation number increased. http://purl.obolibrary.org/obo/OAE_0002140 pain over the liver AE http://purl.obolibrary.org/obo/OAE_0000374 pain AE Pain over the liver AE is a pain AE that shows pain over the liver. http://purl.obolibrary.org/obo/OAE_0002184 numbness of tongue AE http://purl.obolibrary.org/obo/OAE_0001852 numbness AE Numbness of tongue AE is a numbness AE that shows abnormal feeling or loss of sensation in the tongue. http://purl.obolibrary.org/obo/OAE_0002185 numbness of the limbs AE http://purl.obolibrary.org/obo/OAE_0001852 numbness AE Numbness of the limbs AE is a numbness AE that shows reduced or loss of sensation on the skin of the arm and leg. http://purl.obolibrary.org/obo/OAE_0002206 insomnia AE http://purl.obolibrary.org/obo/OAE_0001403 sleep disorder AE a sleep disorder AE in which there is an inability to fall asleep or to stay asleep as long as desired. http://purl.obolibrary.org/obo/OAE_0002214 bleeding and coagulation disorders AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE Bleeding and coagulation disorders AE is a hematopoietic system AE that shows bleeding and coagulation disorders. http://purl.obolibrary.org/obo/OAE_0002220 skin allergy AE http://purl.obolibrary.org/obo/OAE_0000568 allergy AE an allergy AE that shows swelling and irritation of the skin, caused by an allergy to a substance in the environment. http://purl.obolibrary.org/obo/OAE_0002261 acousma AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE Acousma AE is a sensory capability AE that shows a hallucinatory impression of strange sounds. http://purl.obolibrary.org/obo/OAE_0002383 low bone density AE http://purl.obolibrary.org/obo/OAE_0000518 bone AE a bone disorder AE that has an outcome of low bone densityl, but not low enough to be considered osteoporosis http://purl.obolibrary.org/obo/OAE_0002414 gaze palsy AE http://purl.obolibrary.org/obo/OAE_0004344 palsy AE A palsy AE that has a symmetric limitation of the movements of both eyes in the same direction. http://purl.obolibrary.org/obo/OAE_0002421 menstrual disorder AE http://purl.obolibrary.org/obo/OAE_0000082 female reproductive system AE Menstrual disorder AE is an abnormal condition in a woman's menstrual cycle. http://purl.obolibrary.org/obo/OAE_0002425 cognitive disorder AE http://purl.obolibrary.org/obo/OAE_0001797 psychiatric disorder AE a psychiatric disorder AE that is a category of mental health disorders that primarily affect learning, memory, perception, and problem solving, and include amnesia, dementia, and delirium. http://purl.obolibrary.org/obo/OAE_0002440 generalised tonic-clonic seizure AE http://purl.obolibrary.org/obo/OAE_0000579 seizure AE Generalised tonic-clonic seizure AE is a seizure AE that is a type of generalized seizure that affects the entire brain. Tonic–clonic seizures are the seizure type most commonly associated with epilepsy and seizures in general, though it is a misconception that they are the only type. http://purl.obolibrary.org/obo/OAE_0002491 delusion AE http://purl.obolibrary.org/obo/OAE_0001797 psychiatric disorder AE a psychiatric disorder AE that results in a persistent false psychotic belief regarding the self or objects outside the self that is maintained despite indisputable evidence to the contrary. http://purl.obolibrary.org/obo/OAE_0002612 cardiac function test abnormal AE http://purl.obolibrary.org/obo/OAE_0001570 cardiovascular investigation result abnormal AE a cardiovascular investigation result abnormal AE that results in an abnormal result on a test used to evaluate heart function http://purl.obolibrary.org/obo/OAE_0002632 testicular disorder AE http://purl.obolibrary.org/obo/OAE_0000083 male reproductive system AE a male reproductive system AE that has involvement of the testis. http://purl.obolibrary.org/obo/OAE_0002658 euphoria AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE a behavior and neurological AE that has an exaggerated feeling of well-being which is disproportionate to events and stimuli. http://purl.obolibrary.org/obo/OAE_0002665 oligospermia AE http://purl.obolibrary.org/obo/OAE_0000083 male reproductive system AE a male reproductive system AE that has a decrease in the number of spermatozoa in the semen. http://purl.obolibrary.org/obo/OAE_0002807 medical procedure http://purl.obolibrary.org/obo/OAE_0000002 medical intervention a medical intervention that refers to any series of pre-defined steps that should be followed to achieve a desired result. http://purl.obolibrary.org/obo/OAE_0003233 herpes viral infection AE http://purl.obolibrary.org/obo/OAE_0000466 viral infection AE a viral infection AE that is caused by a herpes virus. Note that there are 8 herpesvirus types. http://purl.obolibrary.org/obo/OAE_0003244 aversion to greasy food AE http://purl.obolibrary.org/obo/OAE_0000396 anorexia AE an anorexia AE that has loss of appetite of greasy food. http://purl.obolibrary.org/obo/OAE_0003248 rupture AE http://purl.obolibrary.org/obo/OAE_0000041 injury AE an injury AE that refers to break or burst suddenly (esp. of a pipe, a vessel, or a bodily part such as an organ or membrane) http://purl.obolibrary.org/obo/OAE_0004215 bowel sounds increased AE http://purl.obolibrary.org/obo/OAE_0004217 bowel sounds abnormal AE a bowel sounds abnormal AE that shows an increased amount of bowel sounds. http://purl.obolibrary.org/obo/OAE_0004217 bowel sounds abnormal AE http://purl.obolibrary.org/obo/OAE_0000455 gastrointestinal disorder AE a gastrointestinal disorder AE that shows an abnormal amount of bowel sounds. http://purl.obolibrary.org/obo/OAE_0004220 hyperacusia AE http://purl.obolibrary.org/obo/OAE_0002129 hearing disorder AE a hearing disorder AE with an abnormally disproportionate increase in the sensation of loudness in response to auditory stimuli of normal volume http://purl.obolibrary.org/obo/OAE_0004232 physical examination http://purl.obolibrary.org/obo/OAE_0002807 medical procedure a medical procedure by which a medical professional investigates the body of a patient for signs of disease. http://purl.obolibrary.org/obo/OAE_0004239 visual disturbance AE http://purl.obolibrary.org/obo/OAE_0000443 eye AE an eye disorder AE that causes visual disturbance and interfere with normal sight. http://purl.obolibrary.org/obo/OAE_0004244 eye edema AE http://purl.obolibrary.org/obo/OAE_0000556 edema AE an edema AE that has an outcome of swelling in the eye. http://purl.obolibrary.org/obo/OAE_0004282 necrospermia AE http://purl.obolibrary.org/obo/OAE_0000083 male reproductive system AE a male reproductive system AE in which spermatozoa in seminal fluid are dead or motionless http://purl.obolibrary.org/obo/OAE_0004283 subfertility AE http://purl.obolibrary.org/obo/OAE_0000651 reproductive system AE a reproductive system AE that results in diminished ability to produce live offspring http://purl.obolibrary.org/obo/OAE_0004284 infertility AE http://purl.obolibrary.org/obo/OAE_0000651 reproductive system AE a reproductive system AE that results in an inability to conceive for at least one year after trying and having unprotected sex. http://purl.obolibrary.org/obo/OAE_0004286 dysfunctional uterine bleeding AE http://purl.obolibrary.org/obo/OAE_0000427 hemorrhage AE a hemorrhage AE that occurs at the uterus, but it is not related to menstruation. The irregular and unpredictable bleeding usually comes from a dysfunctional endometrium. http://purl.obolibrary.org/obo/OAE_0004287 testicular atrophy AE http://purl.obolibrary.org/obo/OAE_0002632 testicular disorder AE a testicular disorder AE that has a loss of testicular volume http://purl.obolibrary.org/obo/OAE_0004290 allergic cutaneous vasculitis AE http://purl.obolibrary.org/obo/OAE_0000851 cutaneous vasculitis AE a cutaneous vasculitis AE that results in inflammation of small blood vessels, characterized clinically by palpable purpura, which is a slightly elevated purpuric rash over one or more areas of the kin. http://purl.obolibrary.org/obo/OAE_0004291 melanoplakia AE http://purl.obolibrary.org/obo/OAE_0001397 skin hyperpigmentation AE a skin hyperpigmentation AE that shows the occurrence of pigmented patches on the tongue and buccal mucousmembranes. http://purl.obolibrary.org/obo/OAE_0004293 tonic spasm AE http://purl.obolibrary.org/obo/OAE_0000521 muscle spasm AE a muscle spasm AE that occurs when the contraction of a spasm is sustained or continuing. Such a spasm is generally severe because is is often caused by diseases that affect the central nervous system or brain, such as tetanus, rabies, and cerebral palsy. http://purl.obolibrary.org/obo/OAE_0004299 skin erosion AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE a skin adverse event that has an outcome of a discontinuity of the skin exhibiting incomplete loss of the epidermis, a lesion that is moist, circumscribed, and usually depressed. http://purl.obolibrary.org/obo/OAE_0004300 arrest of hematopoiesis AE http://purl.obolibrary.org/obo/OAE_0000588 hematopoietic system AE a hematopoietic system AE that has an outcome of an arrest of the formation of blood cellular components. http://purl.obolibrary.org/obo/OAE_0004301 acute arrest of hematopoiesis AE http://purl.obolibrary.org/obo/OAE_0004300 arrest of hematopoiesis AE an arrest of hematopoiesis AE that occurs quickly http://purl.obolibrary.org/obo/OAE_0004344 palsy AE http://purl.obolibrary.org/obo/OAE_0000539 paralysis AE A paralysis AE accompanied by involuntary tremors. http://purl.obolibrary.org/obo/OAE_0004348 optic hyperesthesia AE http://purl.obolibrary.org/obo/OAE_0002050 hyperesthesia AE A hyperaesthesia AE that occurs at the optic area, reflected by an abnormal sensitivity to light. http://purl.obolibrary.org/obo/OAE_0004350 myotonia AE http://purl.obolibrary.org/obo/OAE_0000435 muscle AE An muscle AE showing delayed relaxation (prolonged contraction) of the skeletal muscles after voluntary contraction or electrical stimulation http://purl.obolibrary.org/obo/OAE_0004351 neck myotonia AE http://purl.obolibrary.org/obo/OAE_0004350 myotonia AE An myotonia AE that occurs in the neck. http://purl.obolibrary.org/obo/UBERON_0000310 breast http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone The upper ventral region of an animal's torso. http://purl.obolibrary.org/obo/PATO_0001018 physical quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities. http://purl.obolibrary.org/obo/PATO_0001236 process quality http://purl.obolibrary.org/obo/BFO_0000019 quality A quality which inheres in an process. http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/BFO_0000019 quality A quality which inheres in a continuant. http://purl.obolibrary.org/obo/PO_0004518 bark http://purl.obolibrary.org/obo/PO_0009007 portion of plant tissue A portion of plant tissue (PO:0009007) outside the vascular cambium (PO:0005598) or the xylem (PO:0005352); in older trees may be divided into dead outer bark and living inner bark, which consists of secondary phloem (PO:0005043). http://purl.obolibrary.org/obo/PO_0006036 root epidermis http://purl.obolibrary.org/obo/PO_0009007 portion of plant tissue A portion of epidermis (PO:0005679) that is part of a root (PO:0009005). http://purl.obolibrary.org/obo/PO_0009001 fruit http://purl.obolibrary.org/obo/PO_0025496 multi-tissue plant structure A multi-tissue plant structure (PO:0025496) that develops from a gynoecium (PO:0009062), or a single carpel (PO:0009030), and at maturity may have as parts one or more seeds (PO:0009010). http://purl.obolibrary.org/obo/PO_0009005 root http://purl.obolibrary.org/obo/PO_0025004 plant axis A plant axis (PO:0025004) that lacks shoot axis nodes (PO:0005004) and usually grows indeterminately. http://purl.obolibrary.org/obo/PO_0009006 shoot system http://purl.obolibrary.org/obo/PO_0009011 plant structure A collective plant organ structure (PO:0025007) that produces shoot-borne portions of meristem tissue (PO:0009013) and the plant structures (PO:0009011) that arise from them. http://purl.obolibrary.org/obo/PO_0009007 portion of plant tissue http://purl.obolibrary.org/obo/PO_0009011 plant structure A plant structure (PO:0009011) that consists predominantly of similarly specialized plant cells (PO:0009002) of one or more types. http://purl.obolibrary.org/obo/PO_0009008 plant organ http://purl.obolibrary.org/obo/PO_0025496 multi-tissue plant structure A multi-tissue plant structure (PO:0025496) that is a functional unit, is a proper part of a whole plant (PO:0000003), and includes portions of plant tissue (PO:0009007) of at least two different types that derive from a common developmental path. http://purl.obolibrary.org/obo/PO_0009010 seed http://purl.obolibrary.org/obo/PO_0025496 multi-tissue plant structure A multi-tissue plant structure (PO:0025496) that develops from a plant ovule (PO:0020003) and has as parts a plant embryo (PO:0009009) enclosed in a seed coat (PO:0009088). http://purl.obolibrary.org/obo/PO_0009011 plant structure http://purl.obolibrary.org/obo/PO_0025131 plant anatomical entity An anatomical structure that is or was part of a plant, or was derived from a part of a plant. http://purl.obolibrary.org/obo/PO_0009047 stem http://purl.obolibrary.org/obo/PO_0025029 shoot axis A shoot axis (PO:0025029) that is the primary axis of a plant. http://purl.obolibrary.org/obo/PO_0025004 plant axis http://purl.obolibrary.org/obo/PO_0009008 plant organ An axial plant organ (PO:0009008). http://purl.obolibrary.org/obo/PO_0025029 shoot axis http://purl.obolibrary.org/obo/PO_0025004 plant axis A plant axis (PO:0025004) that is part of a shoot system (PO:0009006). http://purl.obolibrary.org/obo/PO_0025034 leaf http://purl.obolibrary.org/obo/PO_0009008 plant organ A phyllome (PO:0006001) that is not associated with a reproductive structure. http://purl.obolibrary.org/obo/PO_0025073 branch http://purl.obolibrary.org/obo/PO_0025029 shoot axis A shoot axis (PO:00025029) that develops from an axillary bud meristem (PO:0000232) or from equal divisions of a meristematic apical cell (PO:0030007). http://purl.obolibrary.org/obo/PO_0025131 plant anatomical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity An anatomical entity that is or was part of a plant. http://purl.obolibrary.org/obo/PO_0025496 multi-tissue plant structure http://purl.obolibrary.org/obo/PO_0009011 plant structure A plant structure (PO:0009011) that has as parts two or more portions of plant tissue (PO:0009007) of at least two different types and which through specific morphogenetic processes forms a single structural unit demarcated by primarily bona-fide boundaries from other structural units of different types. http://purl.obolibrary.org/obo/UBERON_0000017 exocrine pancreas http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element The part of the pancreas that is part of the exocrine system and which produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells [GO]. http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The head is the anterior-most division of the body [GO]. http://purl.obolibrary.org/obo/UBERON_0000057 urethra http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure the fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening http://purl.obolibrary.org/obo/UBERON_0000474 female reproductive system http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system The organs and associated structures associated with bearing offspring in a female animal. http://purl.obolibrary.org/obo/UBERON_0000915 thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Subdivision of trunk that lies between the head and the abdomen. http://purl.obolibrary.org/obo/UBERON_0000991 gonad http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ Reproductive organ that produces and releases eggs (ovary) or sperm (testis). http://purl.obolibrary.org/obo/UBERON_0001003 skin epidermis http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outer epithelial layer of the skin that is superficial to the dermis. http://purl.obolibrary.org/obo/UBERON_0001007 digestive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. http://purl.obolibrary.org/obo/UBERON_0001008 renal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products.. http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]. http://purl.obolibrary.org/obo/UBERON_0001161 body of stomach http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined[GO]. http://purl.obolibrary.org/obo/UBERON_0001173 biliary tree http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder. http://purl.obolibrary.org/obo/UBERON_0001174 common bile duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct the part of the biliary tree formed by the union of the cystic duct and the common hepatic duct http://purl.obolibrary.org/obo/UBERON_0001224 renal pelvis http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A funnel shaped proximal portion of the ureter that is formed by convergence of the major calices [MP]. http://purl.obolibrary.org/obo/UBERON_0001264 pancreas http://purl.obolibrary.org/obo/UBERON_0002075 viscus An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes[GO]. http://purl.obolibrary.org/obo/UBERON_0001456 face http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc). http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel Any of the tubular branching vessels that carry blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/UBERON_0001768 uvea http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest the pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]. http://purl.obolibrary.org/obo/UBERON_0001769 iris http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure the adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye http://purl.obolibrary.org/obo/UBERON_0001775 ciliary body http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure the thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes http://purl.obolibrary.org/obo/UBERON_0001893 telencephalon http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres. http://purl.obolibrary.org/obo/UBERON_0002037 cerebellum http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002067 dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow http://purl.obolibrary.org/obo/UBERON_0012429 hemopoietic tissue the soft tissue that fills the cavities of bones http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. http://purl.obolibrary.org/obo/UBERON_0002390 hematopoietic system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Anatomical system that is involved in the production of hematopoietic cells. http://purl.obolibrary.org/obo/UBERON_0002495 long bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Long bone is a limb bone that is subcylindrical and has a shaft with periosteum separating the ends of the bones. Long bones are present only in the limbs[VSAO:wd]. http://purl.obolibrary.org/obo/UBERON_0003074 mesonephric duct http://purl.obolibrary.org/obo/UBERON_0009201 nephric duct Paired organ that connects the primitive kidney Wolffian body (or mesonephros) to the cloaca and serves as the anlage for certain male reproductive organs. the Wolffian duct is what remains of the pronephric duct after the atrophy of the pronephros[WP]. In Zebrafish: Duct of the adult kidney (mesonephros), present bilaterally ventral to the somites and leading to the cloacal chamber[ZFA]. http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0007329 pancreatic duct http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A duct that is part of the pancreas and connected to the duodenum. http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]. http://purl.obolibrary.org/obo/UBERON_0007798 vascular system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of all blood and lymph vessels. http://purl.obolibrary.org/obo/UBERON_0018707 bladder organ http://purl.obolibrary.org/obo/UBERON_0009856 sac A membranous sac in animals that serves as the receptacle of a liquid or contains gas. http://purl.obolibrary.org/obo/BFO_0000002 continuant http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that has temporal parts and that happens, unfolds or develops through time. http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data item data about an ontology part is a data item about a part of an ontology, for example a term http://purl.obolibrary.org/obo/OBI_0000011 planned process http://purl.obolibrary.org/obo/BFO_0000015 process A processual entity that realizes a plan which is the concretization of a plan specification. http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/BFO_0000030 object A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. http://purl.obolibrary.org/obo/OGMS_0000090 treatment http://purl.obolibrary.org/obo/OBI_0000011 planned process A processual entity whose completion is hypothesized (by a healthcare provider) to alleviate the signs and symptoms associated with a disorder http://purl.obolibrary.org/obo/PATO_0000186 behavioral quality http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation. http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality that inheres in an entire organism or part of an organism. http://purl.obolibrary.org/obo/DRON_00000001 clinical drug role http://purl.obolibrary.org/obo/BFO_0000023 role the role of a material entity to prevent, diagnose, treat, or study disease and/or its effects http://purl.obolibrary.org/obo/CHEBI_131901 pyranopyranone http://purl.obolibrary.org/obo/CHEBI_131900 pyranopyran A pyranopyran in which at least one of the pyran rings in the pyranopyran skeleton is substituted by an oxo group. http://purl.obolibrary.org/obo/CHEBI_15600 (+)-catechin http://purl.obolibrary.org/obo/CHEBI_23053 catechin The (+)-enantiomer of catechin and a polyphenolic antioxidant plant metabolite. http://purl.obolibrary.org/obo/CHEBI_15648 (6aR,11aR)-3,9-dihydroxypterocarpan http://purl.obolibrary.org/obo/CHEBI_26377 pterocarpans A pterocarpan that has formula C15H12O4. http://purl.obolibrary.org/obo/CHEBI_16004 (R)-lactate http://purl.obolibrary.org/obo/CHEBI_24996 lactate An optically active form of lactate having (R)-configuration. http://purl.obolibrary.org/obo/CHEBI_16651 (S)-lactate http://purl.obolibrary.org/obo/CHEBI_24996 lactate An optically active form of lactate having (S)-configuration. http://purl.obolibrary.org/obo/CHEBI_16914 salicylic acid http://purl.obolibrary.org/obo/CHEBI_25389 monohydroxybenzoic acid A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. http://purl.obolibrary.org/obo/CHEBI_17968 butyrate http://purl.obolibrary.org/obo/CHEBI_78115 fatty acid anion 4:0 A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_17984 acyl-CoA http://purl.obolibrary.org/obo/CHEBI_51277 thioester A thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_23053 catechin http://purl.obolibrary.org/obo/CHEBI_72010 hydroxyflavan Members of the class of hydroxyflavan that have a flavan-3-ol skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_23451 cyclitol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom. http://purl.obolibrary.org/obo/CHEBI_24043 flavones http://purl.obolibrary.org/obo/CHEBI_47916 flavonoid A member of the class of flavonoid with a 2-aryl-1-benzopyran-4-one (2-arylchromen-4-one) skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_26912 oxolanes http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any oxacycle having an oxolane (tetrahydrofuran) skeleton. http://purl.obolibrary.org/obo/CHEBI_27300 vitamin D http://purl.obolibrary.org/obo/CHEBI_36853 hydroxy seco-steroid Vitamin D is a group of fat-soluble prohormones, which can be obtained from sun exposure, food and supplements. Vitamin D is biologically inactive and converted to the biologically active calcitriol via double hydroxylation in the body. http://purl.obolibrary.org/obo/CHEBI_28258 vomifoliol http://purl.obolibrary.org/obo/CHEBI_36739 fenchane monoterpenoid A fenchane monoterpenoid that is 3,5,5-trimethylcyclohex-2-en-1-one substituted by a hydroxy and a (1E)-3-hydroxybut-1-en-1-yl group at position 4. http://purl.obolibrary.org/obo/CHEBI_30845 2-furoic acid http://purl.obolibrary.org/obo/CHEBI_36055 furoic acid A furoic acid having the carboxylic acid group located at position 2. http://purl.obolibrary.org/obo/CHEBI_33566 catechols http://purl.obolibrary.org/obo/CHEBI_33570 benzenediols Any compound containing an o-diphenol component. http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated. http://purl.obolibrary.org/obo/CHEBI_36059 hydroxy monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion Any monocarboxylic acid anion carrying at least one hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_36762 abietane diterpenoid http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid based on an abietane skeleton. http://purl.obolibrary.org/obo/CHEBI_36834 3-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid Any hydroxy steroid carrying a hydroxy group at position 3. http://purl.obolibrary.org/obo/CHEBI_37054 3-hydroxybutyrate http://purl.obolibrary.org/obo/CHEBI_84196 3-hydroxy fatty acid anion A hydroxy fatty acid anion that is the conjugate base of 3-hydroxybutyric acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_38672 flavans http://purl.obolibrary.org/obo/CHEBI_47916 flavonoid Any flavonoid with a 3,4-dihydro-2-aryl-2H-1-benzopyran skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_50114 estrogen http://purl.obolibrary.org/obo/CHEBI_50112 sex hormone A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens. http://purl.obolibrary.org/obo/CHEBI_50523 butenolide http://purl.obolibrary.org/obo/CHEBI_37581 gamma-lactone A gamma-lactone that consists of a 2-furanone skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_50856 2-furoate ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any carboxylic ester where the carboxylic acid component is 2-furoic acid. http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion http://purl.obolibrary.org/obo/CHEBI_26079 phosphoric acid derivative An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated. http://purl.obolibrary.org/obo/CHEBI_59554 medium-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid with a chain length of between C6 and C12. http://purl.obolibrary.org/obo/CHEBI_64708 one-carbon compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity An organic molecular entity containing a single carbon atom (C1). http://purl.obolibrary.org/obo/CHEBI_71666 gamma-amino acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion An amino-acid anion in which the amino group is situated gamma- to the carboxylate group. http://purl.obolibrary.org/obo/CHEBI_75772 Saccharomyces cerevisiae metabolite http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae). http://purl.obolibrary.org/obo/CHEBI_76871 EC 2.1.1.* (methyltransferases) inhibitor http://purl.obolibrary.org/obo/CHEBI_76655 EC 2.1.* (C1-transferase) inhibitor An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*). http://purl.obolibrary.org/obo/CHEBI_8100 3-phenyllactate http://purl.obolibrary.org/obo/CHEBI_58896 2-hydroxy carboxylate A 2-hydroxy carboxylate that results from the removal of a proton from the carboxylic acid group of 3-phenyllactic acid. http://purl.obolibrary.org/obo/CHEBI_85234 human blood serum metabolite http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite Any metabolite (endogenous or exogenous) found in human blood serum samples. http://purl.obolibrary.org/obo/CHEBI_15864 luteolin http://purl.obolibrary.org/obo/CHEBI_27741 3'-hydroxyflavonoid A 3'-hydroxyflavonoid which is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immune system modulator. http://purl.obolibrary.org/obo/CHEBI_15901 5,6-dihydrouracil http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone A pyrimidine obtained by formal addition of hydrogen across the 5,6-position of uracil. http://purl.obolibrary.org/obo/CHEBI_17377 bergaptol http://purl.obolibrary.org/obo/CHEBI_52058 5-hydroxyfurocoumarin A 5-hydroxyfurocoumarin that has formula C11H6O4. http://purl.obolibrary.org/obo/CHEBI_18388 apigenin http://purl.obolibrary.org/obo/CHEBI_27116 trihydroxyflavone A trihydroxyflavone that is flavone substituted by hydroxy groups at positions 4', 5 and 7. http://purl.obolibrary.org/obo/CHEBI_23252 cinnamic acids http://purl.obolibrary.org/obo/CHEBI_79020 alpha,beta-unsaturated monocarboxylic acid Any alpha,beta-unsaturated monocarboxylic acid based on the cinnamic acid skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_30566 gamma-aminobutyrate http://purl.obolibrary.org/obo/CHEBI_71666 gamma-amino acid anion An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/CHEBI_4986 fatty acid methyl ester http://purl.obolibrary.org/obo/CHEBI_35748 fatty acid ester A fatty acid ester that is the carboxylic ester obtained by the formal condensation of a fatty acid with methanol. http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. http://purl.obolibrary.org/obo/CHEBI_59558 medium-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid. http://purl.obolibrary.org/obo/CHEBI_60809 adjuvant http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself. http://purl.obolibrary.org/obo/CHEBI_76206 xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced by metabolism of a xenobiotic compound. http://purl.obolibrary.org/obo/CHEBI_132944 octadec-9-enoate http://purl.obolibrary.org/obo/CHEBI_78049 octadecenoate An octadecenoate in which the double bond is at C-9. http://purl.obolibrary.org/obo/CHEBI_132950 tartrate http://purl.obolibrary.org/obo/CHEBI_33798 tetraric acid anion A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of any tartaric acid. http://purl.obolibrary.org/obo/CHEBI_132952 oxalate http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of oxalic acid. http://purl.obolibrary.org/obo/CHEBI_133291 saturated dicarboxylic acid dianion(2-) http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid that contains no carbon-carbon double bonds. http://purl.obolibrary.org/obo/CHEBI_133294 oxo dicarboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion Any dicarboxylic acid dianion carrying one or more oxo groups. http://purl.obolibrary.org/obo/CHEBI_13941 carbamate http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion An amino-acid anion that has formula CH2NO2. http://purl.obolibrary.org/obo/CHEBI_14321 glutamate(1-) http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group http://purl.obolibrary.org/obo/CHEBI_15035 retinal http://purl.obolibrary.org/obo/CHEBI_26534 retinals An enal that consists of 3,7-dimethyl-9-nona-2,4,6,8-tetraenal (double bond geometry unspecified) carrying a 2,6,6-trimethylcyclohex-1-en-1-yl group at the 9-position. http://purl.obolibrary.org/obo/CHEBI_15036 retinoate http://purl.obolibrary.org/obo/CHEBI_26537 retinoid A retinoid that has formula C20H27O2. http://purl.obolibrary.org/obo/CHEBI_15076 selenide http://purl.obolibrary.org/obo/CHEBI_36904 elemental selenium An elemental selenium that has formula Se. http://purl.obolibrary.org/obo/CHEBI_15339 acceptor http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity. http://purl.obolibrary.org/obo/CHEBI_15354 choline http://purl.obolibrary.org/obo/CHEBI_23217 cholines A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. http://purl.obolibrary.org/obo/CHEBI_15356 cysteine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. http://purl.obolibrary.org/obo/CHEBI_15384 limonene http://purl.obolibrary.org/obo/CHEBI_35187 monoterpene A monoterpene that is cyclohex-1-ene substituted by a methyl group at position 1 and a prop-1-en-2-yl group at position 4 respectively. http://purl.obolibrary.org/obo/CHEBI_15595 malate(2-) http://purl.obolibrary.org/obo/CHEBI_61336 C4-dicarboxylate A C4-dicarboxylate resulting from deprotonation of both carboxy groups of malic acid. http://purl.obolibrary.org/obo/CHEBI_15674 2,3-dihydroxybutanedioic acid http://purl.obolibrary.org/obo/CHEBI_26933 tetraric acid A tetraric acid that is butanedioic acid substituted by hydroxy groups at positions 2 and 3. http://purl.obolibrary.org/obo/CHEBI_15693 aldose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals. http://purl.obolibrary.org/obo/CHEBI_15740 formate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects. http://purl.obolibrary.org/obo/CHEBI_15792 malonate(2-) http://purl.obolibrary.org/obo/CHEBI_133291 saturated dicarboxylic acid dianion(2-) A dicarboxylic acid dianion obtained by the deprotonation of the carboxy groups of malonic acid. http://purl.obolibrary.org/obo/CHEBI_16101 ethylbenzene http://purl.obolibrary.org/obo/CHEBI_38976 alkylbenzene An alkylbenzene carrying an ethyl substituent. It is a constituent of coal tar and petroleum. http://purl.obolibrary.org/obo/CHEBI_16112 chlorogenic acid http://purl.obolibrary.org/obo/CHEBI_36087 cinnamate ester A cinnamate ester obtained by formal condensation of the carboxy group of trans-caffeic acid with the 3-hydroxy group of quinic acid. It is an intermediate metabolite in the biosynthesis of lignin. http://purl.obolibrary.org/obo/CHEBI_16134 ammonia http://purl.obolibrary.org/obo/CHEBI_37176 mononuclear parent hydride An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms. http://purl.obolibrary.org/obo/CHEBI_16148 heptadecane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight-chain alkane with 17 carbon atoms. It is a component of essential oils from plants like Opuntia littoralis and Annona squamosa. http://purl.obolibrary.org/obo/CHEBI_16179 retinyl ester http://purl.obolibrary.org/obo/CHEBI_26537 retinoid A carboxylic ester obtained by formal condensation of the hydroxy group of retinol with the carboxy group of any carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_16236 ethanol http://purl.obolibrary.org/obo/CHEBI_50584 alkyl alcohol A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_16247 phospholipid http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides. http://purl.obolibrary.org/obo/CHEBI_16335 adenosine http://purl.obolibrary.org/obo/CHEBI_22260 adenosines A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_16482 naphthalene http://purl.obolibrary.org/obo/CHEBI_35426 ortho-fused bicyclic arene An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia. http://purl.obolibrary.org/obo/CHEBI_16610 spermidine http://purl.obolibrary.org/obo/CHEBI_39474 polyazaalkane A triamine that is the 1,5,10-triaza derivative of decane. http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates. http://purl.obolibrary.org/obo/CHEBI_16701 nucleoside 5'-phosphate http://purl.obolibrary.org/obo/CHEBI_29075 mononucleotide A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated. http://purl.obolibrary.org/obo/CHEBI_16704 uridine http://purl.obolibrary.org/obo/CHEBI_27242 uridines A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a beta-N(1)-glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_16716 benzene http://purl.obolibrary.org/obo/CHEBI_33842 aromatic annulene A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system. http://purl.obolibrary.org/obo/CHEBI_16796 melatonin http://purl.obolibrary.org/obo/CHEBI_27162 tryptamines A member of the class of acetamides that is acetamide in which one of the hydrogens attached to the nitrogen atom is replaced by a 2-(5-methoxy-1H-indol-3-yl)ethyl group. It is a hormone secreted by the pineal gland in humans. http://purl.obolibrary.org/obo/CHEBI_16811 methionine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. http://purl.obolibrary.org/obo/CHEBI_16865 gamma-aminobutyric acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A gamma-amino acid that is butanoic acid with the amino substituent located at C-4. http://purl.obolibrary.org/obo/CHEBI_16933 ergosterol http://purl.obolibrary.org/obo/CHEBI_35348 3beta-sterol A phytosterol consiting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group. http://purl.obolibrary.org/obo/CHEBI_16980 geranial http://purl.obolibrary.org/obo/CHEBI_51688 enal A monoterpenoid that is (2E,6E)-octa-2,6-dienal substituted by methyl groups at positions 3 and 7. http://purl.obolibrary.org/obo/CHEBI_16995 oxalic acid http://purl.obolibrary.org/obo/CHEBI_28383 alpha,omega-dicarboxylic acid An alpha,omega-dicarboxylic acid that is ethane substituted by carboxyl groups at positions 1 and 2. http://purl.obolibrary.org/obo/CHEBI_16997 propane-1,2-diol http://purl.obolibrary.org/obo/CHEBI_26284 propane-1,2-diols The simplest member of the class of propane-1,2-diols, consisting of propane in which a hydrogen at position 1 and a hydrogen at position 2 are substituted by hydroxy groups. A colourless, viscous, hygroscopic, low-melting (-59degreeC) and high-boiling (188degreeC) liquid with low toxicity, it is used as a solvent, emulsifying agent, and antifreeze. http://purl.obolibrary.org/obo/CHEBI_17034 octadecanal http://purl.obolibrary.org/obo/CHEBI_73359 alpha-CH2-containing aldehyde An alpha-CH2-containing aldehyde that has formula C18H36O. http://purl.obolibrary.org/obo/CHEBI_17113 erythritol http://purl.obolibrary.org/obo/CHEBI_48299 butane-1,2,3,4-tetrol The meso-diastereomer of butane-1,2,3,4-tetrol. http://purl.obolibrary.org/obo/CHEBI_17135 long-chain fatty alcohol http://purl.obolibrary.org/obo/CHEBI_24026 fatty alcohol A fatty alcohol with a chain length of C13 or greater. http://purl.obolibrary.org/obo/CHEBI_17169 benzaldehyde http://purl.obolibrary.org/obo/CHEBI_22698 benzaldehydes An arenecarbaldehyde that consists of benzene bearing a single formyl substituent; the simplest aromatic aldehyde and parent of the class of benzaldehydes. http://purl.obolibrary.org/obo/CHEBI_17177 cinnamyl alcohol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A primary alcohol comprising an allyl core with a hydroxy substituent at the 1-position and a phenyl substituent at the 3-position (geometry of the C=C bond unspecified). http://purl.obolibrary.org/obo/CHEBI_17225 salutaridine http://purl.obolibrary.org/obo/CHEBI_25418 morphinane alkaloid A morphinane alkaloid from the opium poppy, in which the 5,6,8,14-tetradehydromorphinan-7-one skeleton is substituted at position 4 by a hydroxyl group, positions 3 and 6 by methoxy groups and position N17 by a methyl group. An intermediate in the biosynthesis of narcotic analgesics such as morphine and codeine. http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose An aldohexose used as a source of energy and metabolic intermediate. http://purl.obolibrary.org/obo/CHEBI_17258 7H-purine http://purl.obolibrary.org/obo/CHEBI_35584 purine The 7H-tautomer of purine. http://purl.obolibrary.org/obo/CHEBI_17309 pectin http://purl.obolibrary.org/obo/CHEBI_24174 galacturonan Any mixture of complex, colloidal, macromolecular plant galacturonans containing a large proportion of D-galactopyranosyluronic acid residues in alpha-(1->4) linkage, the carboxy groups of which may be esterified to varying degrees by methyl groups or be partially or completely converted into salts. The structure shown is that of the parent polygalacturonan. http://purl.obolibrary.org/obo/CHEBI_17376 cystine http://purl.obolibrary.org/obo/CHEBI_35489 organic disulfide A sulfur-containing amino acid obtained by the oxidation of two cysteine molecules which are then linked via a disulfide bond. http://purl.obolibrary.org/obo/CHEBI_17447 geraniol http://purl.obolibrary.org/obo/CHEBI_24221 3,7-dimethylocta-2,6-dien-1-ol A monoterpenoid consisting of two prenyl units linked head-to-tail and functionalised with a hydroxy group at its tail end. http://purl.obolibrary.org/obo/CHEBI_17488 scopoletin http://purl.obolibrary.org/obo/CHEBI_37912 hydroxycoumarin A hydroxycoumarin that is umbelliferone bearing a methoxy substituent at position 6. http://purl.obolibrary.org/obo/CHEBI_17544 hydrogencarbonate http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion The carbon oxoanion resulting from the removal of a proton from carbonic acid. http://purl.obolibrary.org/obo/CHEBI_17563 phthalate(2-) http://purl.obolibrary.org/obo/CHEBI_26092 phthalate A phthalate that is the dianion obtained by the deprotonation of both the carboxy groups of phthalic acid. http://purl.obolibrary.org/obo/CHEBI_17578 toluene http://purl.obolibrary.org/obo/CHEBI_38975 methylbenzene The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent. http://purl.obolibrary.org/obo/CHEBI_17745 coniferol http://purl.obolibrary.org/obo/CHEBI_33853 phenols A phenylpropanoid that is one of the main monolignols, produced by the reduction of the carboxy functional group in cinnamic acid and the addition of a hydroxy and a methoxy substituent to the aromatic ring. http://purl.obolibrary.org/obo/CHEBI_17750 glycine betaine http://purl.obolibrary.org/obo/CHEBI_22860 amino-acid betaine The amino acid betaine derived from glycine. http://purl.obolibrary.org/obo/CHEBI_17790 methanol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group. http://purl.obolibrary.org/obo/CHEBI_17822 serine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_17846 (S)-naringenin http://purl.obolibrary.org/obo/CHEBI_50202 naringenin The (S)-enantiomer of naringenin. http://purl.obolibrary.org/obo/CHEBI_17891 donor http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity. http://purl.obolibrary.org/obo/CHEBI_18002 (-)-secologanin http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde An iridoid monoterpenoid that is acetaldehyde in which on of the hydrogens of the methyl group has been replaced by a 2-(beta-D-glucopyranosyloxy)-3,4-dihydro-2H-pyran-4-yl group which is substituted at positions 3 and 5 by a vinyl and a methoxycarbonyl group, respectively (the 2S,3R,4S stereoisomer). http://purl.obolibrary.org/obo/CHEBI_18012 fumaric acid http://purl.obolibrary.org/obo/CHEBI_22958 butenedioic acid A butenedioic acid in which the C=C double bond has E geometry. It is an intermediate metabolite in the citric acid cycle. http://purl.obolibrary.org/obo/CHEBI_18052 loganate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that has formula C16H23O10. http://purl.obolibrary.org/obo/CHEBI_18088 formononetin http://purl.obolibrary.org/obo/CHEBI_55465 7-hydroxyisoflavones A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by a methoxy group at position 4'. http://purl.obolibrary.org/obo/CHEBI_18135 catechol http://purl.obolibrary.org/obo/CHEBI_33566 catechols A benzenediol comprising of a benzene core carrying two hydroxy substituents ortho to each other. http://purl.obolibrary.org/obo/CHEBI_18154 polysaccharide http://purl.obolibrary.org/obo/CHEBI_33694 biomacromolecule A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues. http://purl.obolibrary.org/obo/CHEBI_18237 glutamic acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2. http://purl.obolibrary.org/obo/CHEBI_18248 iron atom http://purl.obolibrary.org/obo/CHEBI_33356 iron group element atom An iron group element atom that has atomic number 26. http://purl.obolibrary.org/obo/CHEBI_18282 nucleobase http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound That part of DNA or RNA that may be involved in pairing. http://purl.obolibrary.org/obo/CHEBI_18291 manganese atom http://purl.obolibrary.org/obo/CHEBI_33352 manganese group element atom A manganese group element atom that has formula Mn. http://purl.obolibrary.org/obo/CHEBI_18330 isovitexin http://purl.obolibrary.org/obo/CHEBI_20857 C-glycosyl compound A C-glycosyl compound that consists of apigenin substituted by a 1,5-anhydro-D-glucitol moiety at position 6. http://purl.obolibrary.org/obo/CHEBI_18346 vanillin http://purl.obolibrary.org/obo/CHEBI_22698 benzaldehydes A member of the class of benzaldehydes carrying methoxy and hydroxy substituents at positions 3 and 4 respectively. http://purl.obolibrary.org/obo/CHEBI_18367 phosphate(3-) http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion A phosphate ion that is the conjugate base of hydrogenphosphate. http://purl.obolibrary.org/obo/CHEBI_18401 phenylacetate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of phenylacetic acid. http://purl.obolibrary.org/obo/CHEBI_18420 magnesium(2+) http://purl.obolibrary.org/obo/CHEBI_39127 magnesium cation A magnesium cation that has formula Mg. http://purl.obolibrary.org/obo/CHEBI_22153 acaricide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance used to destroy pests of the subclass Acari (mites and ticks). http://purl.obolibrary.org/obo/CHEBI_22210 aconitate(3-) http://purl.obolibrary.org/obo/CHEBI_27092 tricarboxylic acid trianion A tricarboxylic acid trianion that is the conjugate base of aconitic acid. http://purl.obolibrary.org/obo/CHEBI_22660 aspartic acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent http://purl.obolibrary.org/obo/CHEBI_22718 benzoates http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid. http://purl.obolibrary.org/obo/CHEBI_22750 benzylisoquinoline alkaloid http://purl.obolibrary.org/obo/CHEBI_24921 isoquinoline alkaloid Any isoquinoline alkaloid based on a benzylisoquinoline skeleton. http://purl.obolibrary.org/obo/CHEBI_22976 cadinene http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene Any sesquiterpene having a cadinane skeleton containing one or more C=C bonds. http://purl.obolibrary.org/obo/CHEBI_23044 carotenoid http://purl.obolibrary.org/obo/CHEBI_26935 tetraterpenoid One of a class of tetraterpenoids (C40), formally derived from the acyclic parent, psi,psi-carotene by hydrogenation, dehydrogenation, cyclization, oxidation, or combination of these processes. This class includes carotenes, xanthophylls and certain compounds that arise from rearrangement of the skeleton of psi,psi-carotene or by loss of part of this structure. Retinoids are excluded. http://purl.obolibrary.org/obo/CHEBI_23217 cholines http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion A quaternary ammonium ion based on the choline ion and its substituted derivatives thereof. http://purl.obolibrary.org/obo/CHEBI_23248 cinnamate http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid A member of the class of cinnamates that results from the deprotonation of the carboxy group of cinnamic acid. http://purl.obolibrary.org/obo/CHEBI_23509 cysteine derivative http://purl.obolibrary.org/obo/CHEBI_83821 amino acid derivative An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues. http://purl.obolibrary.org/obo/CHEBI_23888 drug http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. http://purl.obolibrary.org/obo/CHEBI_24433 group http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A defined linked collection of atoms or a single atom within a molecular entity. http://purl.obolibrary.org/obo/CHEBI_24621 hormone http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. http://purl.obolibrary.org/obo/CHEBI_24913 isoprenoid http://purl.obolibrary.org/obo/CHEBI_18059 lipid Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives. http://purl.obolibrary.org/obo/CHEBI_25017 leucine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group. http://purl.obolibrary.org/obo/CHEBI_25115 malate http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of malic acid. http://purl.obolibrary.org/obo/CHEBI_25187 p-menthan-3-ol http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol Any secondary alcohol that is one of the eight possible diastereoisomers of 5-methyl-2-(propan-2-yl)cyclohexan-1-ol. http://purl.obolibrary.org/obo/CHEBI_25389 monohydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_24676 hydroxybenzoic acid Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring. http://purl.obolibrary.org/obo/CHEBI_25418 morphinane alkaloid http://purl.obolibrary.org/obo/CHEBI_24921 isoquinoline alkaloid An isoquinoline alkaloid based on a morphinan skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_25626 octadecadienoate http://purl.obolibrary.org/obo/CHEBI_57560 long-chain fatty acid anion A long-chain, unsaturated fatty acid anion formed by deprotonation of the carboxy group of any octadecadienoic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_25728 osmolyte http://purl.obolibrary.org/obo/CHEBI_24432 biological role A solute used by a cell under water stress to maintain cell volume. http://purl.obolibrary.org/obo/CHEBI_25826 p-menthane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A monoterpene that has formula C10H20. http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin. http://purl.obolibrary.org/obo/CHEBI_26094 benzenedicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid A member of the class of benzoic acids in that consists of benzene substituted by two carboxy groups. http://purl.obolibrary.org/obo/CHEBI_26188 polyketide http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides. http://purl.obolibrary.org/obo/CHEBI_26536 retinoic acid http://purl.obolibrary.org/obo/CHEBI_26537 retinoid A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraenoic acid substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified). http://purl.obolibrary.org/obo/CHEBI_26606 sapogenin http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound Any organic polycyclic compound that is the aglycon moiety of a saponin; sapogenins may be steroids or triterpenoids. http://purl.obolibrary.org/obo/CHEBI_26650 serine family amino acid http://purl.obolibrary.org/obo/CHEBI_83813 proteinogenic amino acid An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class. http://purl.obolibrary.org/obo/CHEBI_26666 short-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid. http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group http://purl.obolibrary.org/obo/CHEBI_37838 carboacyl group A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_27208 unsaturated fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid containing at least one C=C or C#C bond. http://purl.obolibrary.org/obo/CHEBI_27510 umbelliferone http://purl.obolibrary.org/obo/CHEBI_37912 hydroxycoumarin A hydroxycoumarin that is coumarin substituted by a hydroxy group ay position 7. http://purl.obolibrary.org/obo/CHEBI_27741 3'-hydroxyflavonoid http://purl.obolibrary.org/obo/CHEBI_24698 hydroxyflavone Any hydroxyflavone with a hydroxy substituent at position 3'. http://purl.obolibrary.org/obo/CHEBI_28197 daidzein http://purl.obolibrary.org/obo/CHEBI_55465 7-hydroxyisoflavones A member of the class of 7-hydroxyisoflavones that is 7-hydroxyisoflavone substituted by an additional hydroxy group at position 4'. http://purl.obolibrary.org/obo/CHEBI_28358 rac-lactic acid http://purl.obolibrary.org/obo/CHEBI_60911 racemate A racemate comprising equimolar amounts of (R)- and (S)-lactic acid. http://purl.obolibrary.org/obo/CHEBI_28499 kaempferol http://purl.obolibrary.org/obo/CHEBI_52267 7-hydroxyflavonol A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. http://purl.obolibrary.org/obo/CHEBI_28616 carbamic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised. http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid. http://purl.obolibrary.org/obo/CHEBI_28885 butan-1-ol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A primary alcohol that is butane in which a hydrogen of one of the methyl groups is substituted by a hydroxy group. It it produced in small amounts in humans by the gut microbes. http://purl.obolibrary.org/obo/CHEBI_28976 carbonic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid A chalcocarbonic acid that has formula CH2O3. http://purl.obolibrary.org/obo/CHEBI_29033 iron(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation An iron cation that has formula Fe. http://purl.obolibrary.org/obo/CHEBI_29069 phthalic acid http://purl.obolibrary.org/obo/CHEBI_26094 benzenedicarboxylic acid A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions. http://purl.obolibrary.org/obo/CHEBI_29751 (-)-quinate http://purl.obolibrary.org/obo/CHEBI_26490 quinate A quinate that is the conjugate base of (-)-quinic acid. http://purl.obolibrary.org/obo/CHEBI_29987 glutamate(2-) http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion A dicarboxylic acid dianion that is the conjugate base of glutamate(1-). http://purl.obolibrary.org/obo/CHEBI_30031 succinate(2-) http://purl.obolibrary.org/obo/CHEBI_61336 C4-dicarboxylate A dicarboxylic acid dianion resulting from the removal of a proton from both of the carboxy groups of succinic acid. http://purl.obolibrary.org/obo/CHEBI_30746 benzoic acid http://purl.obolibrary.org/obo/CHEBI_22723 benzoic acids A compound comprising a benzene ring core carrying a carboxylic acid substituent. http://purl.obolibrary.org/obo/CHEBI_30762 salicylate http://purl.obolibrary.org/obo/CHEBI_25388 monohydroxybenzoate A monohydroxybenzoate that is the conjugate base of salicylic acid. http://purl.obolibrary.org/obo/CHEBI_30768 propionic acid http://purl.obolibrary.org/obo/CHEBI_26666 short-chain fatty acid A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group. http://purl.obolibrary.org/obo/CHEBI_30769 citric acid http://purl.obolibrary.org/obo/CHEBI_27093 tricarboxylic acid A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms. http://purl.obolibrary.org/obo/CHEBI_30779 succinate(1-) http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion A dicarboxylic acid monoanion resulting from the removal of a proton from one of the carboxy groups of succinic acid. http://purl.obolibrary.org/obo/CHEBI_30794 malonic acid http://purl.obolibrary.org/obo/CHEBI_28383 alpha,omega-dicarboxylic acid An alpha,omega-dicarboxylic acid in which the two carboxy groups are separated by a single methylene group. http://purl.obolibrary.org/obo/CHEBI_30823 oleate http://purl.obolibrary.org/obo/CHEBI_132944 octadec-9-enoate A C18, long straight-chain monounsaturated fatty acid anion; and the conjugate base of oleic acid, arising from deprotonation of the carboxylic acid group. http://purl.obolibrary.org/obo/CHEBI_30879 alcohol http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. http://purl.obolibrary.org/obo/CHEBI_30929 2,3-dihydroxybutanedioate http://purl.obolibrary.org/obo/CHEBI_61336 C4-dicarboxylate A tartaric acid anion that is the conjugate base of 3-carboxy-2,3-dihydroxypropanoate. http://purl.obolibrary.org/obo/CHEBI_32456 cysteinate(1-) http://purl.obolibrary.org/obo/CHEBI_63470 sulfur-containing amino-acid anion A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32458 cysteinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that has formula C3H8NO2S. http://purl.obolibrary.org/obo/CHEBI_32507 glycinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that is the conjugate acid of glycine, arising from protonation of the amino. http://purl.obolibrary.org/obo/CHEBI_32508 glycinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that is the conjugate base of glycine, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32544 nicotinate http://purl.obolibrary.org/obo/CHEBI_38181 pyridinemonocarboxylate A pyridinemonocarboxylate that is the conjugate base of nicotinic acid, arising from deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_32926 octadecane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight-chain alkane carrying 18 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_33249 organyl group http://purl.obolibrary.org/obo/CHEBI_51447 organic univalent group Any organic substituent group, regardless of functional type, having one free valence at a carbon atom. http://purl.obolibrary.org/obo/CHEBI_33252 atomic nucleus http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle A nucleus is the positively charged central portion of an atom, excluding the orbital electrons. http://purl.obolibrary.org/obo/CHEBI_33284 nutrient http://purl.obolibrary.org/obo/CHEBI_78295 food component A nutrient is a chemical element needed by all life forms. http://purl.obolibrary.org/obo/CHEBI_33447 phospho sugar http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid. http://purl.obolibrary.org/obo/CHEBI_33709 amino acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid A carboxylic acid containing one or more amino groups. http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside http://purl.obolibrary.org/obo/CHEBI_21731 N-glycosyl compound An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents. http://purl.obolibrary.org/obo/CHEBI_35107 azane http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride Saturated acyclic nitrogen hydrides having the general formula NnHn+2. http://purl.obolibrary.org/obo/CHEBI_35190 diterpene http://purl.obolibrary.org/obo/CHEBI_35186 terpene A C20 terpene. http://purl.obolibrary.org/obo/CHEBI_35237 cysteine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion that has formula C3H7NO2S. http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups. http://purl.obolibrary.org/obo/CHEBI_35397 tartrate(1-) http://purl.obolibrary.org/obo/CHEBI_48929 3-carboxy-2,3-dihydroxypropanoate A 3-carboxy-2,3-dihydroxypropanoate that is the conjugate base of tartaric acid. http://purl.obolibrary.org/obo/CHEBI_35481 non-narcotic analgesic http://purl.obolibrary.org/obo/CHEBI_35480 analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion Any dicarboxylic acid anion that is a monoanion obtained by the deprotonation of only one of the carboxy groups of the dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_35746 fatty aldehyde http://purl.obolibrary.org/obo/CHEBI_59768 aliphatic aldehyde An aldehyde formally arising from reduction of the carboxylic acid group of its corresponding fatty acid, having a carbonyl group at one end of the carbon chain. http://purl.obolibrary.org/obo/CHEBI_35819 branched-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid in which the parent hydrocarbon chain has one or more alkyl substituents; a common component in animal and bacterial lipids. The fatty acyl chain is usually saturated and the substituent a methyl group; however, unsaturated BCFAs are found in marine animals, and branches other than methyl are found in microbial lipids. http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug http://purl.obolibrary.org/obo/CHEBI_36043 antimicrobial drug Any antimicrobial drug which is used to treat or prevent protozoal infections. http://purl.obolibrary.org/obo/CHEBI_36021 octadec-9-enoic acid http://purl.obolibrary.org/obo/CHEBI_25634 octadecenoic acid An octadecenoic acid with a double bond at C-9. http://purl.obolibrary.org/obo/CHEBI_36145 oxo dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_25754 oxo carboxylic acid Any dicarboxylic acid carrying one or more oxo groups. http://purl.obolibrary.org/obo/CHEBI_36180 butenedioate http://purl.obolibrary.org/obo/CHEBI_61336 C4-dicarboxylate A C4-dicarboxylate that has formula C4H2O4. http://purl.obolibrary.org/obo/CHEBI_36208 shikimate http://purl.obolibrary.org/obo/CHEBI_36126 cyclohexenecarboxylate A cyclohexenecarboxylate that is the conjugate base of shikimic acid. http://purl.obolibrary.org/obo/CHEBI_36281 caffeic acid http://purl.obolibrary.org/obo/CHEBI_33566 catechols A hydroxycinnamic acid that is cinnamic acid in which the phenyl ring is substituted by hydroxy groups at positions 3 and 4. It exists in cis and trans forms; the latter is the more common. http://purl.obolibrary.org/obo/CHEBI_36540 ent-kaurane http://purl.obolibrary.org/obo/CHEBI_35190 diterpene A diterpene that has formula C20H34. http://purl.obolibrary.org/obo/CHEBI_36773 camphor http://purl.obolibrary.org/obo/CHEBI_23446 cyclic monoterpene ketone A cyclic monoterpene ketone that is bornane bearing an oxo substituent at position 2. A naturally occurring monoterpenoid. http://purl.obolibrary.org/obo/CHEBI_37527 acid http://purl.obolibrary.org/obo/CHEBI_51086 chemical role An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). http://purl.obolibrary.org/obo/CHEBI_38068 antimalarial http://purl.obolibrary.org/obo/CHEBI_64915 antiplasmodial drug A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. http://purl.obolibrary.org/obo/CHEBI_38181 pyridinemonocarboxylate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of a pyridinemonocarboxylic acid. A 'closed class'. http://purl.obolibrary.org/obo/CHEBI_38324 cholinergic agonist http://purl.obolibrary.org/obo/CHEBI_38323 cholinergic drug Any drug that binds to and activates cholinergic receptors. http://purl.obolibrary.org/obo/CHEBI_38742 tetrahydroxyflavanone http://purl.obolibrary.org/obo/CHEBI_24697 hydroxyflavanone A hydroxyflavanone with atleast four hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_38755 hydroxyisoflavone http://purl.obolibrary.org/obo/CHEBI_38757 isoflavones Member of the class of isoflavones bearing at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_42111 (R)-lactic acid http://purl.obolibrary.org/obo/CHEBI_78320 2-hydroxypropanoic acid An optically active form of lactic acid having (R)-configuration. http://purl.obolibrary.org/obo/CHEBI_46904 oxalate(1-) http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion A dicarboxylic acid monoanion that is the conjugate base of oxalic acid. http://purl.obolibrary.org/obo/CHEBI_47786 16-oxo steroid http://purl.obolibrary.org/obo/CHEBI_35789 oxo steroid Any oxo steroid carrying an oxo group at position 16. http://purl.obolibrary.org/obo/CHEBI_47909 3-oxo Delta(4)-steroid http://purl.obolibrary.org/obo/CHEBI_51689 enone A 3-oxo steroid conjugated to a C=C double bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_47916 flavonoid http://purl.obolibrary.org/obo/CHEBI_72544 flavonoids Any member of the 'superclass' flavonoids whose skeleton is based on 1-benzopyran with an aryl substituent at position 2. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds. http://purl.obolibrary.org/obo/CHEBI_48929 3-carboxy-2,3-dihydroxypropanoate http://purl.obolibrary.org/obo/CHEBI_132950 tartrate A tartaric acid anion that is the conjugate base of 2,3-dihydroxybutanedioic acid. http://purl.obolibrary.org/obo/CHEBI_4917 eugenol http://purl.obolibrary.org/obo/CHEBI_33853 phenols A phenylpropanoid formally derived from guaiacol with an allyl chain substituted para to the hydroxy group. http://purl.obolibrary.org/obo/CHEBI_50211 retinol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A retinoid consisting of 3,7-dimethylnona-2,4,6,8-tetraen-1-ol substituted at position 9 by a 2,6,6-trimethylcyclohex-1-en-1-yl group (geometry of the four exocyclic double bonds is not specified). http://purl.obolibrary.org/obo/CHEBI_50247 antidote http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any protective agent counteracting or neutralizing the action of poisons. http://purl.obolibrary.org/obo/CHEBI_50406 probe http://purl.obolibrary.org/obo/CHEBI_33232 application A role played by a molecular entity used to study the microscopic environment. http://purl.obolibrary.org/obo/CHEBI_50630 cyclooxygenase 1 inhibitor http://purl.obolibrary.org/obo/CHEBI_35544 EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. http://purl.obolibrary.org/obo/CHEBI_50699 oligosaccharide http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues. http://purl.obolibrary.org/obo/CHEBI_50905 teratogenic agent http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. http://purl.obolibrary.org/obo/CHEBI_50910 neurotoxin http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A poison that interferes with the functions of the nervous system. http://purl.obolibrary.org/obo/CHEBI_50926 angiogenesis modulating agent http://purl.obolibrary.org/obo/CHEBI_23888 drug An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents. http://purl.obolibrary.org/obo/CHEBI_51086 chemical role http://purl.obolibrary.org/obo/BFO_0000023 role A role played by the molecular entity or part thereof within a chemical context. http://purl.obolibrary.org/obo/CHEBI_57287 coenzyme A(4-) http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion Tetraanion of coenzyme A. http://purl.obolibrary.org/obo/CHEBI_57305 glycine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of glycine. http://purl.obolibrary.org/obo/CHEBI_57347 3-oxo-fatty acyl-CoA(4-) http://purl.obolibrary.org/obo/CHEBI_90726 3-oxoacyl-CoA(4-) An acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate groups of any 3-oxo-fatty acyl-CoA. http://purl.obolibrary.org/obo/CHEBI_58951 short-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6). http://purl.obolibrary.org/obo/CHEBI_58956 branched-chain saturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_58955 branched-chain fatty acid anion Any saturated fatty acid anion with a carbon side-chain or isopropyl termination. http://purl.obolibrary.org/obo/CHEBI_59202 straight-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid whose skeletal carbon atoms form an unbranched open chain. http://purl.obolibrary.org/obo/CHEBI_59203 straight-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid. http://purl.obolibrary.org/obo/CHEBI_59740 nucleophilic reagent http://purl.obolibrary.org/obo/CHEBI_39144 Lewis base A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons. http://purl.obolibrary.org/obo/CHEBI_59814 L-alpha-amino acid anion http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group. http://purl.obolibrary.org/obo/CHEBI_59869 L-alpha-amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_78608 alpha-amino acid zwitterion Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group. http://purl.obolibrary.org/obo/CHEBI_60242 monovalent inorganic cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one. http://purl.obolibrary.org/obo/CHEBI_60643 NMDA receptor antagonist http://purl.obolibrary.org/obo/CHEBI_60798 excitatory amino acid antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. http://purl.obolibrary.org/obo/CHEBI_61336 C4-dicarboxylate http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion A dicarboxylate that contains four carbon atoms. http://purl.obolibrary.org/obo/CHEBI_61903 oxo-fatty acyl-CoA http://purl.obolibrary.org/obo/CHEBI_37554 fatty acyl-CoA A fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any oxo-fatty acid. http://purl.obolibrary.org/obo/CHEBI_62049 acyl donor http://purl.obolibrary.org/obo/CHEBI_17891 donor Any donor that can transfer acyl groups between molecular entities. http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds. http://purl.obolibrary.org/obo/CHEBI_63563 oligosaccharide derivative http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from an oligosaccharide. http://purl.obolibrary.org/obo/CHEBI_63703 (-)-delta-cadinene http://purl.obolibrary.org/obo/CHEBI_22976 cadinene A member of the cadinene family of sesquiterpenes in which the double bonds are located at the 4-4a and 7-8 positions, and in which the isopropyl group at position 1 is cis to the hydrogen at the adjacent bridgehead carbon (the 1R,8aS-enantiomer). http://purl.obolibrary.org/obo/CHEBI_63794 retinoid X receptor agonist http://purl.obolibrary.org/obo/CHEBI_48705 agonist An agonist that selectively binds to and activates a retinoid X receptor. http://purl.obolibrary.org/obo/CHEBI_64570 EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76874 EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1). http://purl.obolibrary.org/obo/CHEBI_6650 malic acid http://purl.obolibrary.org/obo/CHEBI_66873 C4-dicarboxylic acid A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_66873 C4-dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid Any dicarboxylic acid that contains four carbon atoms. http://purl.obolibrary.org/obo/CHEBI_67013 methyl-branched fatty acid anion http://purl.obolibrary.org/obo/CHEBI_58955 branched-chain fatty acid anion Any branched-chain fatty acid anion containing methyl branches only. http://purl.obolibrary.org/obo/CHEBI_67198 retinoic acid receptor agonist http://purl.obolibrary.org/obo/CHEBI_90708 retinoic acid receptor modulator An agonist that selectively binds to and activates a retinoic acid receptor. http://purl.obolibrary.org/obo/CHEBI_67199 AP-1 antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist An antogonist that interferes with the action of activator protein 1 (AP-1). http://purl.obolibrary.org/obo/CHEBI_71476 EC 2.3.1.85 (fatty acid synthase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis. http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any molecule that consists of at least one carbon atom as part of the electrically neutral entity. http://purl.obolibrary.org/obo/CHEBI_73359 alpha-CH2-containing aldehyde http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde An aldehyde of general formula R-CH2-CH=O in which the aldehydic C=O function is attached to a CH2 group at the alpha-position. http://purl.obolibrary.org/obo/CHEBI_76395 EC 2.3.1.48 (histone acetyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48). http://purl.obolibrary.org/obo/CHEBI_76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76834 EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*). http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*). http://purl.obolibrary.org/obo/CHEBI_76989 phytoestrogen http://purl.obolibrary.org/obo/CHEBI_50114 estrogen Any compound produced by a plant that happens to have estrogenic activity. http://purl.obolibrary.org/obo/CHEBI_77131 sinapic acid http://purl.obolibrary.org/obo/CHEBI_33853 phenols A monohydroxycinnamic acid that is cinnamic acid in which the phenyl hydrogens at positions 3, 4, and 5 are replaced by methoxy, hydroxy, and methoxy groups, respectively. http://purl.obolibrary.org/obo/CHEBI_77396 long-chain primary fatty alcohol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A long-chain fatty alcohol in which the hydroxy group is attached to a methylene (CH2) group. http://purl.obolibrary.org/obo/CHEBI_77523 Maillard reaction product http://purl.obolibrary.org/obo/CHEBI_77521 thermal degradation product Any thermal degradation product obtained as a result of a chemical reaction between an amino acid and a reducing sugar (Maillard reaction, a non-enzymatic browning procedure that usually imparts flavour to starch-based food products). http://purl.obolibrary.org/obo/CHEBI_77941 EC 3.5.1.4 (amidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4). http://purl.obolibrary.org/obo/CHEBI_78049 octadecenoate http://purl.obolibrary.org/obo/CHEBI_82680 monounsaturated fatty acid anion A fatty acid anion containing 18 carbons and one double bond. Formed by deprotonation of the carboxylic acid group. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78675 fundamental metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced by all living cells. http://purl.obolibrary.org/obo/CHEBI_7896 hexadecanoate http://purl.obolibrary.org/obo/CHEBI_57560 long-chain fatty acid anion A long-chain fatty acid anion that is the conjugate base of hexadecanoic acid (palmitic acid); major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_79388 divalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of two. http://purl.obolibrary.org/obo/CHEBI_83411 beta-D-glucosiduronate http://purl.obolibrary.org/obo/CHEBI_132367 acceptor beta-D-glucuronoside(1-) A carbohydrate acid derivative anion obtained by deprotonation of the carboxy group of any beta-D-glucosiduronic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_84196 3-hydroxy fatty acid anion http://purl.obolibrary.org/obo/CHEBI_59835 hydroxy fatty acid anion A hydroxy fatty acid anion obtained by deprotonation of the carboxy group of any 3-hydroxy fatty acid. http://purl.obolibrary.org/obo/CHEBI_84588 trans-2,3-unsaturated fatty aldehyde http://purl.obolibrary.org/obo/CHEBI_35746 fatty aldehyde A fatty aldehyde with a trans-double bond at carbon 2. http://purl.obolibrary.org/obo/CHEBI_29340 hydridonitrate(2-) http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride A divalent inorganic anion resulting from the removal of two protons from ammonia. http://purl.obolibrary.org/obo/CHEBI_29994 D-aspartate(2-) http://purl.obolibrary.org/obo/CHEBI_29995 aspartate(2-) An aspartate(2-) that is the conjugate base of D-aspartate(1-). http://purl.obolibrary.org/obo/CHEBI_29995 aspartate(2-) http://purl.obolibrary.org/obo/CHEBI_61336 C4-dicarboxylate A C4-dicarboxylate that is the dianion obtained by the deprotonation of both the carboxy groups of aspartic acid. http://purl.obolibrary.org/obo/CHEBI_30165 boron(1+) http://purl.obolibrary.org/obo/CHEBI_33610 monoatomic boron A monoatomic boron that has formula B. http://purl.obolibrary.org/obo/CHEBI_30207 phosphorus(.) http://purl.obolibrary.org/obo/CHEBI_33466 monoatomic phosphorus A monoatomic phosphorus that has formula P. http://purl.obolibrary.org/obo/CHEBI_30240 fluorine(1+) http://purl.obolibrary.org/obo/CHEBI_36895 monoatomic fluorine A monoatomic fluorine that has formula F. http://purl.obolibrary.org/obo/CHEBI_30807 tetradecanoate http://purl.obolibrary.org/obo/CHEBI_78121 fatty acid anion 14:0 A long-chain fatty acid anion that is the conjugate base of myristic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_31014 lignocerate http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion A straight-chain saturated fatty acid anion that is the conjugate base of lignoceric acid, formed by deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32695 argininate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that has formula C6H13N4O2. http://purl.obolibrary.org/obo/CHEBI_32696 argininium(1+) http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that has formula C6H15N4O2. http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_24433 group Any substituent group which does not contain carbon. http://purl.obolibrary.org/obo/CHEBI_33658 arene http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon Any monocyclic or polycyclic aromatic hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_33702 polyatomic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation A cation consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_36337 strychnidine http://purl.obolibrary.org/obo/CHEBI_38514 quinoline alkaloid fundamental parent A quinoline alkaloid fundamental parent that has formula C21H24N2O. http://purl.obolibrary.org/obo/CHEBI_38716 carboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion Any dianion containing at least one carboxy group. http://purl.obolibrary.org/obo/CHEBI_49468 silver(1+) http://purl.obolibrary.org/obo/CHEBI_60242 monovalent inorganic cation A silver cation that has formula Ag. http://purl.obolibrary.org/obo/CHEBI_50313 onium cation http://purl.obolibrary.org/obo/CHEBI_50312 onium compound Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families. http://purl.obolibrary.org/obo/CHEBI_51060 hormone agonist http://purl.obolibrary.org/obo/CHEBI_51061 hormone receptor modulator A chemical substance which binds to specific hormone receptors activating the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. http://purl.obolibrary.org/obo/CHEBI_53666 kaurane diterpenoid http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid compound having a kaurane skeleton. http://purl.obolibrary.org/obo/CHEBI_58588 flavonol oxoanion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion The conjugate base of a flavonol compound. http://purl.obolibrary.org/obo/CHEBI_62031 polar amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_26167 polar amino acid Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group. http://purl.obolibrary.org/obo/CHEBI_63056 zinc cation http://purl.obolibrary.org/obo/CHEBI_27365 zinc ion Any zinc ion that is positively charged. http://purl.obolibrary.org/obo/CHEBI_64634 kaempferol O-glucoside http://purl.obolibrary.org/obo/CHEBI_50018 glycosyloxyflavone A glycosyloxyflavone that is an O-glucosylated derivative of kaempferol. http://purl.obolibrary.org/obo/CHEBI_64857 cosmetic http://purl.obolibrary.org/obo/CHEBI_33232 application The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it. http://purl.obolibrary.org/obo/CHEBI_72004 hexadec-9-enoic acid http://purl.obolibrary.org/obo/CHEBI_24548 hexadecenoic acid A hexadecenoic acid in which the double bond is located at position 9. http://purl.obolibrary.org/obo/CHEBI_90700 strychnine(1+) http://purl.obolibrary.org/obo/CHEBI_60521 indole alkaloid cation An indole alkaloid cation obtained by protonation of the tertiary amino group of strychnine. http://purl.obolibrary.org/obo/CHEBI_42630 propylbenzene http://purl.obolibrary.org/obo/CHEBI_38976 alkylbenzene An alkylbenzene that is benzene having one of its aromatic hydrogens substituted by a propyl group. http://purl.obolibrary.org/obo/CHEBI_4381 Delcosine http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid that has formula C24H39NO7. http://purl.obolibrary.org/obo/CHEBI_4384 Delphinine http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid that has formula C33H45NO9. http://purl.obolibrary.org/obo/CHEBI_4401 Denudatin B http://purl.obolibrary.org/obo/CHEBI_35259 benzofurans A benzofuran that has formula C21H24O5. http://purl.obolibrary.org/obo/CHEBI_51374 GABA agent http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. http://purl.obolibrary.org/obo/CHEBI_71224 flavan-3,3',4',5,5',7-hexol http://purl.obolibrary.org/obo/CHEBI_72010 hydroxyflavan A hydroxyflavan that is 3,4-dihydro-2H-chromene which is substituted at positions 3, 5, and 7 by hydroxy groups, and at position 2 by a 3,4,5-trihydroxyphenyl group. http://purl.obolibrary.org/obo/CHEBI_71227 (+)-epigallocatechin http://purl.obolibrary.org/obo/CHEBI_71224 flavan-3,3',4',5,5',7-hexol A flavan-3,3',4',5,5',7-hexol that has (2S,3S)-configuration. http://purl.obolibrary.org/obo/CHEBI_72490 2-(hydroxymethyl)piperidine-3,4,5-triol http://purl.obolibrary.org/obo/CHEBI_48590 hydroxypiperidine A hydroxypiperidine that has three hydroxy groups located at positions 3, 4 and 5 as well as a hydroxymethyl substituent at position 2. http://purl.obolibrary.org/obo/CHEBI_77659 emodin(1-) http://purl.obolibrary.org/obo/CHEBI_50525 phenolate anion A phenolate anion that is the conjugate base of emodin, obtained by deprotonation of the phenolic hydroxy group at position 2; major species at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_78795 pentadecanoate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A straight-chain, saturated fatty acid anion resulting from the deprotonation of the carboxy group of pentadecanoic acid. It is the major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_79007 tricosanoate http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion A very long-chain fatty acid anion that is the conjugate base of tricosanoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_85049 EC 1.10.3.1 (catechol oxidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_85048 EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of catechol oxidase (EC 1.10.3.1). http://purl.obolibrary.org/obo/CHEBI_85050 EC 1.10.3.2 (laccase) inhibitor http://purl.obolibrary.org/obo/CHEBI_85048 EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor Any EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor that interferes with the action of laccase (EC 1.10.3.2). http://purl.obolibrary.org/obo/CHEBI_85051 EC 1.13.11.24 (quercetin 2,3-dioxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor Any EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor that interferes with the action of quercetin 2,3-dioxygenase (EC 1.13.1.24). http://purl.obolibrary.org/obo/CHEBI_85052 EC 1.4.3.3 (D-amino-acid oxidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76861 EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor Any EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of D-amino-acid oxidase (EC 1.4.3.3). http://purl.obolibrary.org/obo/CHEBI_5831 Hypaconitine http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid that has formula C33H45NO10. http://purl.obolibrary.org/obo/CHEBI_59016 neohesperidin http://purl.obolibrary.org/obo/CHEBI_48024 3'-hydroxyflavanones A flavanone glycoside that is hesperitin having an 2-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety attached to the 7-hydroxy group. http://purl.obolibrary.org/obo/CHEBI_60247 silver ion http://purl.obolibrary.org/obo/CHEBI_33966 elemental silver A silver atom having a net electric charge. http://purl.obolibrary.org/obo/CHEBI_64641 divalent inorganic cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation An inorganic cation with a valency of two. http://purl.obolibrary.org/obo/CHEBI_67486 quercetin 3-O-beta-D-galactopyranoside http://purl.obolibrary.org/obo/CHEBI_76424 quercetin O-glycoside A quercetin O-glycoside that is quercetin with a beta-D-galactosyl residue attached at position 3. Isolated from Artemisia capillaris, it exhibits hepatoprotective activity. http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*). http://purl.obolibrary.org/obo/CHEBI_76845 EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme using a miscellaneous compound as one donor and incorporating one atom of oxygen (EC 1.14.18.*). http://purl.obolibrary.org/obo/CHEBI_76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76661 EC 2.3.* (acyltransferase) inhibitor An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*). http://purl.obolibrary.org/obo/CHEBI_6773 Mesaconitine http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid that has formula C33H45NO11. http://purl.obolibrary.org/obo/CHEBI_67894 uvaol http://purl.obolibrary.org/obo/CHEBI_36615 triterpenoid A triterpenoid that has formula C30H50O2. http://purl.obolibrary.org/obo/CHEBI_67939 erythrodiol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A pentacyclic triterpenoid that is beta-amyrin in which one of the hydrogens of the methyl group at position 28 has been replaced by a hydroxy group. It is a plant metabolite found in olive oil as well as in Rhododendron ferrugineum and other Rhododendron species. http://purl.obolibrary.org/obo/CHEBI_67949 3beta-acetoxyolean-18-en-28-oic acid http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is olean-18-ene substituted by an acetyloxy group at position 3 and a carboxy group at position 28. It has been isolated from Juglans sinensis. http://purl.obolibrary.org/obo/CHEBI_67951 3-oxo-23-hydroxyurs-12-en-28-oic acid http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is urs-12-ene substituted by an oxo group at position 3, a carboxy group at position 28 and a hydroxy group at position 23. It has been isolated from Juglans sinensis. http://purl.obolibrary.org/obo/CHEBI_68103 3-epioleanolic acid http://purl.obolibrary.org/obo/CHEBI_36615 triterpenoid A triterpenoid that has formula C30H48O3. http://purl.obolibrary.org/obo/CHEBI_68939 Tracheloside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside A lignan that has formula C27H34O12. http://purl.obolibrary.org/obo/CHEBI_68992 nantenine http://purl.obolibrary.org/obo/CHEBI_24921 isoquinoline alkaloid An isoquinoline alkaloid that has formula C20H21NO4. http://purl.obolibrary.org/obo/CHEBI_69080 methyl linoleate http://purl.obolibrary.org/obo/CHEBI_4986 fatty acid methyl ester A fatty acid methyl ester of linoleic acid. It has been isolated from Neolitsea daibuensis. http://purl.obolibrary.org/obo/CHEBI_69187 Methyl palmitate http://purl.obolibrary.org/obo/CHEBI_4986 fatty acid methyl ester A fatty acid methyl ester that has formula C17H34O2. http://purl.obolibrary.org/obo/CHEBI_69431 ergosta-4,6,8(14),22-tetraen-3-one http://purl.obolibrary.org/obo/CHEBI_50403 ergostanoid An ergostanoid that is (22E)-ergosta-4,6,8(14),22-tetraene substituted by an oxo group at position 3. It has been isolated from the mycelia of Cordyceps sinensis. http://purl.obolibrary.org/obo/CHEBI_9908 ursolic acid http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is urs-12-en-28-oic acid substituted by a beta-hydroxy group at position 3. http://purl.obolibrary.org/obo/CHEBI_77117 EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any such enzyme acting on the C-N bond of nitriles (EC 3.5.5.*). http://purl.obolibrary.org/obo/CHEBI_77413 tetracosan-1-ol http://purl.obolibrary.org/obo/CHEBI_78142 fatty alcohol 24:0 A long-chain primary fatty alcohol that is tetracosane in which a hydrogen attached to one of the terminal carbons is replaced by a hydroxy group. It has been isolated from a variety of plants, including grape seeds, evening primrose (Oenothera biennis), pitaya fruits (Hylocereus polyrhizus and Hylocereus undatus), and the flowers of Arabian jasmine (Jasminum sambac). http://purl.obolibrary.org/obo/CHEBI_77470 heptadecan-1-ol http://purl.obolibrary.org/obo/CHEBI_77396 long-chain primary fatty alcohol A long-chain fatty alcohol that is heptadecane in which one of the terminal methyl hydrogens is replaced by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_77521 thermal degradation product http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any product obtained as a result of thermally induced non-enzymatic degradation. http://purl.obolibrary.org/obo/CHEBI_78123 fatty acid anion 16:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 16 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78142 fatty alcohol 24:0 http://purl.obolibrary.org/obo/CHEBI_24026 fatty alcohol Any fatty alcohol containing 24 carbons. http://purl.obolibrary.org/obo/CHEBI_78309 alpha-asarone http://purl.obolibrary.org/obo/CHEBI_78308 asarone The trans-isomer of asarone. http://purl.obolibrary.org/obo/CHEBI_78315 4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one http://purl.obolibrary.org/obo/CHEBI_51689 enone A carbobicyclic compound that is bicyclo[3.1.1]heptane which is substituted by an oxo group at position 2 and by methyl groups at positions 4, 6 and 6, and which contains a double bond between positions 3 and 4. http://purl.obolibrary.org/obo/CHEBI_78316 (S)-(-)-verbenone http://purl.obolibrary.org/obo/CHEBI_78315 4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one A 4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one in which both chiral centres have S configuration. http://purl.obolibrary.org/obo/CHEBI_9955 (R)-(+)-verbenone http://purl.obolibrary.org/obo/CHEBI_78315 4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one A 4,6,6-trimethylbicyclo[3.1.1]hept-3-en-2-one in which both chiral centres have R configuration. It is a component of Spanish verbena oil, from Verbena triphylla. http://purl.obolibrary.org/obo/CHEBI_87529 myrcenol http://purl.obolibrary.org/obo/CHEBI_26878 tertiary alcohol A monoterpenoid that is oct-7-en-2-ol substituted by a methyl group at position 2 and a methylidene group at position 6 respectively. http://purl.obolibrary.org/obo/CHEBI_87604 1,1,6-trimethyltetralin http://purl.obolibrary.org/obo/CHEBI_35428 ortho-fused bicyclic hydrocarbon A member of the class of tetralins that is tetralin substituted by methyl groups at positions 1, 1 and 6 respectively. http://purl.obolibrary.org/obo/CHEBI_87609 3-furaldehyde http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde An aldehyde that is furan substituted by a formyl group at position 3. http://purl.obolibrary.org/obo/CHEBI_88534 Linalyl oxide http://purl.obolibrary.org/obo/CHEBI_26912 oxolanes An oxolane that has formula C10H18O2. http://purl.obolibrary.org/obo/CHEBI_9740 tripdiolide http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle An oxacycle that has formula C20H24O7. http://purl.obolibrary.org/obo/CHEBI_9747 triptolide http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle An oxacycle that has formula C20H24O6. http://purl.obolibrary.org/obo/CHEBI_9783 Tutin http://purl.obolibrary.org/obo/CHEBI_37581 gamma-lactone A gamma-lactone that has formula C15H18O6. http://purl.obolibrary.org/obo/UBERON_0000010 peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. http://purl.obolibrary.org/obo/UBERON_0000016 endocrine pancreas http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The part of the pancreas that is part of the endocrine system and is made up of islet cells, which produce insulin, glucagon and somatostatin. http://purl.obolibrary.org/obo/UBERON_0000020 sense organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is capable of transducing sensory stimulus to the nervous system. http://purl.obolibrary.org/obo/UBERON_0000056 ureter http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Muscular duct that propels urine from the kidneys to the urinary bladder, or related organs. http://purl.obolibrary.org/obo/UBERON_0000160 intestine http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. http://purl.obolibrary.org/obo/UBERON_0000165 mouth http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). http://purl.obolibrary.org/obo/UBERON_0000178 blood http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid A fluid that is composed of blood plasma and erythrocytes. http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. http://purl.obolibrary.org/obo/UBERON_0000945 stomach http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0000948 heart http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. http://purl.obolibrary.org/obo/UBERON_0000949 endocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. http://purl.obolibrary.org/obo/UBERON_0000955 brain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. http://purl.obolibrary.org/obo/UBERON_0000964 cornea http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure the transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure http://purl.obolibrary.org/obo/UBERON_0000965 lens of camera-type eye http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure Transparent part of camera-type eye that helps to refract light to be focused on the retina. http://purl.obolibrary.org/obo/UBERON_0000966 retina http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/UBERON_0000970 eye http://purl.obolibrary.org/obo/UBERON_0000020 sense organ An organ that detects light. http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs concerned with reproduction. http://purl.obolibrary.org/obo/UBERON_0000992 female gonad http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ the gonad of a female organism which contains germ cells http://purl.obolibrary.org/obo/UBERON_0000995 uterus http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct the female muscular organ of gestation in which the developing embryo or fetus is nourished until birth http://purl.obolibrary.org/obo/UBERON_0001004 respiratory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Functional system which consists of structures involved in respiration. http://purl.obolibrary.org/obo/UBERON_0001016 nervous system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. http://purl.obolibrary.org/obo/UBERON_0001017 central nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information. http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue Muscle tissue that consists primarily of skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0001165 pyloric antrum http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach the area at the bottom of the stomach on the caudal side of the pyloric canal that contains gastrin-producing G cells, which stimulate acid production, and the luminal pH-sensitive population of somatostatin-producing D cells http://purl.obolibrary.org/obo/UBERON_0001166 pylorus http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach the stomach tissue region surrounding and controlling the distal outlet of the stomach, which opens into the duodenum http://purl.obolibrary.org/obo/UBERON_0001245 anus http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Orifice at the opposite end of an animal's digestive tract from the mouth. Its function is to expel feces, unwanted semi-solid matter produced during digestion, which, depending on the type of animal, may be one or more of: matter which the animal cannot digest, such as bones; food material after all the nutrients have been extracted, for example cellulose or lignin; ingested matter which would be toxic if it remained in the digestive tract; and dead or excess gut bacteria and other endosymbionts. http://purl.obolibrary.org/obo/UBERON_0001255 urinary bladder http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP]. http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]. http://purl.obolibrary.org/obo/UBERON_0001705 nail http://purl.obolibrary.org/obo/UBERON_0009564 distal limb integumentary appendage A horn-like keratin structure covering the dorsal aspect of the terminal phalanges of fingers and toes[WP]. http://purl.obolibrary.org/obo/UBERON_0001711 eyelid http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A fold of skin that covers and protects part of the eyeball. Examples: upper eyelid, lower eyelid, nictitating membrane http://purl.obolibrary.org/obo/UBERON_0001776 optic choroid http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]. http://purl.obolibrary.org/obo/UBERON_0001982 capillary http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel Any of the smallest blood vessels connecting arterioles with venules. http://purl.obolibrary.org/obo/UBERON_0002101 limb http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin A paired appendage that is evolved from a paired fin. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the girdle and its parts. http://purl.obolibrary.org/obo/UBERON_0002107 liver http://purl.obolibrary.org/obo/UBERON_0006925 digestive gland An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. http://purl.obolibrary.org/obo/UBERON_0002108 small intestine http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Subdivision of digestive tract that connects the stomach to the large intestine and is where much of the digestion and absorption of food takes place (with the exception of ruminants). The mammalian small intestine is long and coiled and can be differentiated histologically into: duodenum, jejunem, ileum[WP,cjm,Kardong]. http://purl.obolibrary.org/obo/UBERON_0002110 gall bladder http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera An organ that aids digestion and stores bile produced by the liver[WP]. http://purl.obolibrary.org/obo/UBERON_0002113 kidney http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A paired organ of the urinary tract which has the production of urine as its primary function. http://purl.obolibrary.org/obo/UBERON_0002114 duodenum http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The first part of the small intestine. At the junction of the stomach and the duodenum the alimentary canal is inflected. The duodenum first goes anteriorly for a short distance, turns dorsally, and eventually caudally, thus it is a U-shaped structure with two horizontal sections (a ventral and a dorsal one). http://purl.obolibrary.org/obo/UBERON_0002204 musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the muscular and skeletal systems. http://purl.obolibrary.org/obo/UBERON_0002240 spinal cord http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO) http://purl.obolibrary.org/obo/UBERON_0002298 brainstem http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]. http://purl.obolibrary.org/obo/UBERON_0002330 exocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. http://purl.obolibrary.org/obo/UBERON_0002394 bile duct http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine. http://purl.obolibrary.org/obo/UBERON_0002405 immune system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. http://purl.obolibrary.org/obo/UBERON_0002416 integumental system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An organ involved in reproduction http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ A female organ involved in reproduction http://purl.obolibrary.org/obo/UBERON_0003221 phalanx http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element Endochondral bones that are often elongate and arranged in rows of articulating elements, and form the visible part of the digits. http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the heart and blood vessels. http://purl.obolibrary.org/obo/UBERON_0004913 hepatopancreatic ampulla http://purl.obolibrary.org/obo/UBERON_0002394 bile duct A dilation of the duodenal papilla that is the opening of the juncture of the common bile duct and the main pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0005409 alimentary part of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The part of the digestive system that excludes the hepatobiliary system. http://purl.obolibrary.org/obo/UBERON_0006562 pharynx http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. http://purl.obolibrary.org/obo/CHEBI_10019 Vomicine http://purl.obolibrary.org/obo/CHEBI_48513 carbazoles A carbazole that has formula C22H24N2O4. http://purl.obolibrary.org/obo/CHEBI_10039 Wilfordine http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid A sesquiterpenoid that has formula C43H49NO19. http://purl.obolibrary.org/obo/CHEBI_10213 alpha-amyrin http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol A pentacyclic triterpenoid that is ursane which contains a double bond between positions 12 and 13 and in which the hydrogen at the 3beta position is substituted by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_131604 Mycoplasma genitalium metabolite http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. http://purl.obolibrary.org/obo/CHEBI_133004 bisbenzylisoquinoline alkaloid http://purl.obolibrary.org/obo/CHEBI_22750 benzylisoquinoline alkaloid A type of benzylisoquinoline alkaloid whose structures are built up of two benzylisoquinoline units linked by ether bridges. Various structural patterns resulting from additional bridging between the two units by direct carbon-carbon bridging or by methylenedioxy groups are common. http://purl.obolibrary.org/obo/CHEBI_15705 L-alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid Any alpha-amino acid having L-configuration at the alpha-carbon. http://purl.obolibrary.org/obo/CHEBI_16708 adenine http://purl.obolibrary.org/obo/CHEBI_20706 6-aminopurines The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6. http://purl.obolibrary.org/obo/CHEBI_17087 ketone http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H). http://purl.obolibrary.org/obo/CHEBI_17120 hexanoate http://purl.obolibrary.org/obo/CHEBI_78116 fatty acid anion 6:0 A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid). http://purl.obolibrary.org/obo/CHEBI_17568 uracil http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. http://purl.obolibrary.org/obo/CHEBI_17859 glutaric acid http://purl.obolibrary.org/obo/CHEBI_28383 alpha,omega-dicarboxylic acid An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_18220 isoflavone http://purl.obolibrary.org/obo/CHEBI_38757 isoflavones A simplest member of the class of isoflavones that is 4H-chromen-4-one in which the hydrogen at position 3 is replaced by a phenyl group. http://purl.obolibrary.org/obo/CHEBI_18358 methoxsalen http://purl.obolibrary.org/obo/CHEBI_26369 psoralens A member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. http://purl.obolibrary.org/obo/CHEBI_18946 delta-lactone http://purl.obolibrary.org/obo/CHEBI_25000 lactone A lactone having a six-membered lactone ring. http://purl.obolibrary.org/obo/CHEBI_20706 6-aminopurines http://purl.obolibrary.org/obo/CHEBI_22527 aminopurine Any compound having 6-aminopurine (adenine) as part of its structure. http://purl.obolibrary.org/obo/CHEBI_20857 C-glycosyl compound http://purl.obolibrary.org/obo/CHEBI_63161 glycosyl compound A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a carbon atom, thus creating a C-C bond. http://purl.obolibrary.org/obo/CHEBI_21731 N-glycosyl compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond. http://purl.obolibrary.org/obo/CHEBI_22160 acetamides http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide Compounds with the general formula RNHC(=O)CH3. http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. http://purl.obolibrary.org/obo/CHEBI_22586 antioxidant http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. http://purl.obolibrary.org/obo/CHEBI_22587 antiviral agent http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent A substance that destroys or inhibits replication of viruses. http://purl.obolibrary.org/obo/CHEBI_22712 benzenes http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_22723 benzoic acids http://purl.obolibrary.org/obo/CHEBI_33859 aromatic carboxylic acid Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group. http://purl.obolibrary.org/obo/CHEBI_23990 ethyl ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any carboxylic ester resulting from the formal condensation of the carboxy group of a carboxylic acid with ethanol. http://purl.obolibrary.org/obo/CHEBI_24026 fatty alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol An aliphatic alcohol consisting of a chain of 8 to 22 carbon atoms. Fatty alcohols may be saturated or unsaturated and may be branched or unbranched. http://purl.obolibrary.org/obo/CHEBI_24373 glycine derivative http://purl.obolibrary.org/obo/CHEBI_83811 proteinogenic amino acid derivative A proteinogenic amino acid derivative resulting from reaction of glycine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom. http://purl.obolibrary.org/obo/CHEBI_24780 imidazoles http://purl.obolibrary.org/obo/CHEBI_23677 diazole A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. http://purl.obolibrary.org/obo/CHEBI_24828 indoles http://purl.obolibrary.org/obo/CHEBI_22728 benzopyrrole Any compound containing an indole skeleton. http://purl.obolibrary.org/obo/CHEBI_24922 isoquinolines http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound A class of organic heteropolycyclic compound consisting of isoquinoline and its substitution derivatives. http://purl.obolibrary.org/obo/CHEBI_24995 lactam http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. http://purl.obolibrary.org/obo/CHEBI_25036 lignan http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid Any phenylpropanoid derived from phenylalanine via dimerization of substituted cinnamic alcohols, known as monolignols, to a dibenzylbutane skeleton. Note that while individual members of the class have names ending ...lignane, ...lignene, ...lignadiene, etc., the class names lignan, neolignan, etc., do not end with an "e". http://purl.obolibrary.org/obo/CHEBI_25106 macrolide http://purl.obolibrary.org/obo/CHEBI_26188 polyketide A macrocyclic lactone with a ring of twelve or more members derived from a polyketide. http://purl.obolibrary.org/obo/CHEBI_25212 metabolite http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. http://purl.obolibrary.org/obo/CHEBI_25235 monomethoxybenzene http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzene Compounds containing a benzene skeleton substituted with one methoxy group. http://purl.obolibrary.org/obo/CHEBI_25248 methyl ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol. http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid An oxoacid containing a single carboxy group. http://purl.obolibrary.org/obo/CHEBI_25477 naphthalenes http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings. http://purl.obolibrary.org/obo/CHEBI_25697 organic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation Any organic ion with a net positive charge. http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol http://purl.obolibrary.org/obo/CHEBI_33853 phenols Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_26267 proanthocyanidin http://purl.obolibrary.org/obo/CHEBI_26848 tannin A flavonoid oligomer obtained by the the condensation of two or more units of hydroxyflavans. http://purl.obolibrary.org/obo/CHEBI_26420 pyridinemonocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33859 aromatic carboxylic acid A monocarboxylic acid in which the carboxy group is attached to a pyridine (or substituted pyridine) ring. http://purl.obolibrary.org/obo/CHEBI_26421 pyridines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). http://purl.obolibrary.org/obo/CHEBI_26848 tannin http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol Any of a group of astringent polyphenolic vegetable principles or compounds, chiefly complex glucosides of catechol and pyrogallol. http://purl.obolibrary.org/obo/CHEBI_26878 tertiary alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it. http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound http://purl.obolibrary.org/obo/CHEBI_36688 heterotricyclic compound An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms. http://purl.obolibrary.org/obo/CHEBI_27093 tricarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid An oxoacid containing three carboxy groups. http://purl.obolibrary.org/obo/CHEBI_27162 tryptamines http://purl.obolibrary.org/obo/CHEBI_24828 indoles Tryptamine and its substitution derivatives. http://purl.obolibrary.org/obo/CHEBI_28425 alpha-carotene http://purl.obolibrary.org/obo/CHEBI_35163 cyclic carotene A cyclic carotene with a beta- and an epsilon-ring at opposite ends respectively. http://purl.obolibrary.org/obo/CHEBI_28794 coumarin http://purl.obolibrary.org/obo/CHEBI_23403 coumarins A chromenone having the keto group located at the 2-position. http://purl.obolibrary.org/obo/CHEBI_29105 zinc(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation A zinc cation that has formula Zn. http://purl.obolibrary.org/obo/CHEBI_29347 monocarboxylic acid amide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A carboxamide derived from a monocarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_29348 fatty amide http://purl.obolibrary.org/obo/CHEBI_29347 monocarboxylic acid amide A monocarboxylic acid amide derived from a fatty acid. http://purl.obolibrary.org/obo/CHEBI_32955 epoxide http://purl.obolibrary.org/obo/CHEBI_37407 cyclic ether Any cyclic ether in which the oxygen atom forms part of a 3-membered ring. http://purl.obolibrary.org/obo/CHEBI_33229 vitamin http://purl.obolibrary.org/obo/CHEBI_78295 food component An organic substance that is distributed in foodstuffs, is distinct from the main organic components of food (protein, carbohydrate and fat) and is needed for the normal nutrition of the organism in question. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines. http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_24432 biological role A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. http://purl.obolibrary.org/obo/CHEBI_33282 antibacterial agent http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent A substance that kills or slows the growth of bacteria. http://purl.obolibrary.org/obo/CHEBI_33288 rodenticide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance used to destroy rodent pests. http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester http://purl.obolibrary.org/obo/CHEBI_35701 ester An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion An amino-acid anion obtained by deprotonation of any alpha-amino acid. http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. http://purl.obolibrary.org/obo/CHEBI_33599 spiro compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound A compound having one atom as the only common member of two rings. http://purl.obolibrary.org/obo/CHEBI_33643 cycloalkene http://purl.obolibrary.org/obo/CHEBI_33664 monocyclic hydrocarbon An unsaturated monocyclic hydrocarbon having at least one endocyclic double bond. http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group. http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2). http://purl.obolibrary.org/obo/CHEBI_33853 phenols http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. http://purl.obolibrary.org/obo/CHEBI_33859 aromatic carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring. http://purl.obolibrary.org/obo/CHEBI_35147 (6'R)-beta,epsilon-carotene http://purl.obolibrary.org/obo/CHEBI_28425 alpha-carotene An alpha-carotene that has formula C40H56. http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene http://purl.obolibrary.org/obo/CHEBI_35186 terpene A C15 terpene. http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion http://purl.obolibrary.org/obo/CHEBI_33702 polyatomic cation Ammonium, NH4(+), and derivatives formed by substitution by univalent groups. http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity Any heteroorganic entity containing at least one carbon-nitrogen bond. http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. http://purl.obolibrary.org/obo/CHEBI_35441 antiinfective agent http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance used in the prophylaxis or therapy of infectious diseases. http://purl.obolibrary.org/obo/CHEBI_35470 central nervous system drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. http://purl.obolibrary.org/obo/CHEBI_35472 anti-inflammatory drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance that reduces or suppresses inflammation. http://purl.obolibrary.org/obo/CHEBI_35480 analgesic http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. http://purl.obolibrary.org/obo/CHEBI_35488 central nervous system depressant http://purl.obolibrary.org/obo/CHEBI_35470 central nervous system drug A loosely defined group of drugs that tend to reduce the activity of the central nervous system. http://purl.obolibrary.org/obo/CHEBI_35489 organic disulfide http://purl.obolibrary.org/obo/CHEBI_48343 disulfide Compounds of structure RSSR in which R and R' are organic groups. http://purl.obolibrary.org/obo/CHEBI_35610 antineoplastic agent http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance that inhibits or prevents the proliferation of neoplasms. http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Any ether in which the oxygen is attached to at least one aryl substituent. http://purl.obolibrary.org/obo/CHEBI_35620 vasodilator agent http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug A drug used to cause dilation of the blood vessels. http://purl.obolibrary.org/obo/CHEBI_35623 anticonvulsant http://purl.obolibrary.org/obo/CHEBI_35488 central nervous system depressant A drug used to prevent seizures or reduce their severity. http://purl.obolibrary.org/obo/CHEBI_35674 antihypertensive agent http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it. http://purl.obolibrary.org/obo/CHEBI_35711 ursane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A triterpene that has formula C30H52. http://purl.obolibrary.org/obo/CHEBI_35718 antifungal agent http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. http://purl.obolibrary.org/obo/CHEBI_35748 fatty acid ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester A carboxylic ester in which the carboxylic acid component can be any fatty acid. http://purl.obolibrary.org/obo/CHEBI_35990 bridged compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound A polycyclic compound in which two rings have two or more atoms in common. http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. http://purl.obolibrary.org/obo/CHEBI_36615 triterpenoid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid Any terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound An organochalcogen compound containing at least one carbon-oxygen bond. http://purl.obolibrary.org/obo/CHEBI_37154 fumarate(1-) http://purl.obolibrary.org/obo/CHEBI_37155 hydrogen butenedioate A hydrogen butenedioate obtained by deprotonation of one of the carboxy groups of fumaric acid. http://purl.obolibrary.org/obo/CHEBI_37581 gamma-lactone http://purl.obolibrary.org/obo/CHEBI_25000 lactone A lactone having a five-membered lactone ring. http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide http://purl.obolibrary.org/obo/CHEBI_33256 primary amide An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom. http://purl.obolibrary.org/obo/CHEBI_37667 sesquiterpene lactone http://purl.obolibrary.org/obo/CHEBI_37668 terpene lactone Any member of a diverse class of complex, multicyclic phytochemicals showing a variety of skeleton arrangements and bioactivities, and having in common a sesquiterpenoid structure including a lactone ring. http://purl.obolibrary.org/obo/CHEBI_37948 oxaspiro compound http://purl.obolibrary.org/obo/CHEBI_33599 spiro compound A spiro compound in which at least one of the cyclic components is an oxygen heterocyle. http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any organic heterocyclic compound containing at least one ring oxygen atom. http://purl.obolibrary.org/obo/CHEBI_38325 muscarinic agonist http://purl.obolibrary.org/obo/CHEBI_38324 cholinergic agonist Any drug that binds to and activates a muscarinic cholinergic receptor. http://purl.obolibrary.org/obo/CHEBI_38958 indole alkaloid http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid An alkaloid containing an indole skeleton. http://purl.obolibrary.org/obo/CHEBI_38976 alkylbenzene http://purl.obolibrary.org/obo/CHEBI_33847 monocyclic arene A monocyclic arene that is benzene substituted with one or more alkyl groups. http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines http://purl.obolibrary.org/obo/CHEBI_38313 diazines Any compound having a pyrimidine as part of its structure. http://purl.obolibrary.org/obo/CHEBI_46955 anthracenes http://purl.obolibrary.org/obo/CHEBI_51269 acenes Compounds containing an anthracene skeleton. http://purl.obolibrary.org/obo/CHEBI_48422 angiogenesis inhibitor http://purl.obolibrary.org/obo/CHEBI_23888 drug An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. http://purl.obolibrary.org/obo/CHEBI_48550 EC 1.1.1.21 (aldehyde reductase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76835 EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). http://purl.obolibrary.org/obo/CHEBI_49164 (6S,9R)-vomifoliol http://purl.obolibrary.org/obo/CHEBI_49156 (6S)-vomifoliol A (6S)-vomifoliol with a R configuration for the hydroxy group at position 9. http://purl.obolibrary.org/obo/CHEBI_50176 keratolytic drug http://purl.obolibrary.org/obo/CHEBI_50177 dermatologic drug A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. http://purl.obolibrary.org/obo/CHEBI_50183 P450 inhibitor http://purl.obolibrary.org/obo/CHEBI_76898 EC 1.14.14.1 (unspecific monooxygenase) inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. http://purl.obolibrary.org/obo/CHEBI_50267 protective agent http://purl.obolibrary.org/obo/CHEBI_23888 drug Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent. http://purl.obolibrary.org/obo/CHEBI_50629 cyclooxygenase 2 inhibitor http://purl.obolibrary.org/obo/CHEBI_35544 EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. http://purl.obolibrary.org/obo/CHEBI_50750 EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor http://purl.obolibrary.org/obo/CHEBI_70727 topoisomerase inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (topoisomerase II), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_33582 carbon group molecular entity Any molecular entity that contains carbon. http://purl.obolibrary.org/obo/CHEBI_50903 carcinogenic agent http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. http://purl.obolibrary.org/obo/CHEBI_50995 secondary amino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups. http://purl.obolibrary.org/obo/CHEBI_51307 diester http://purl.obolibrary.org/obo/CHEBI_35701 ester A diester is a compound containing two ester groups. http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzene http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups. http://purl.obolibrary.org/obo/CHEBI_51689 enone http://purl.obolibrary.org/obo/CHEBI_51721 alpha,beta-unsaturated ketone An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_52214 ligand http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any molecule or ion capable of binding to a central metal atom to form coordination complexes. http://purl.obolibrary.org/obo/CHEBI_52898 azamacrocycle http://purl.obolibrary.org/obo/CHEBI_51026 macrocycle A cyclic macromolecule containing one or more nitrogen atoms in place of carbon either as the divalent group NH for the group CH2 or a single trivalent nitrogen atom for the group CH. http://purl.obolibrary.org/obo/CHEBI_53756 HIV-1 reverse transcriptase inhibitor http://purl.obolibrary.org/obo/CHEBI_52629 EC 3.1.26.13 (retroviral ribonuclease H) inhibitor An entity which inhibits the activity of HIV-1 reverse transcriptase. http://purl.obolibrary.org/obo/CHEBI_55465 7-hydroxyisoflavones http://purl.obolibrary.org/obo/CHEBI_38755 hydroxyisoflavone A hydroxyisoflavone compound having a hydroxy group at the 7-position. http://purl.obolibrary.org/obo/CHEBI_60027 polymer http://purl.obolibrary.org/obo/CHEBI_60004 mixture A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.. http://purl.obolibrary.org/obo/CHEBI_60911 racemate http://purl.obolibrary.org/obo/CHEBI_60004 mixture A racemate is an equimolar mixture of a pair of enantiomers. http://purl.obolibrary.org/obo/CHEBI_61655 steroid saponin http://purl.obolibrary.org/obo/CHEBI_26605 saponin Any saponin derived from a hydroxysteroid. http://purl.obolibrary.org/obo/CHEBI_61778 triterpenoid saponin http://purl.obolibrary.org/obo/CHEBI_61777 terpene glycoside A terpene glycoside in which the terpene moiety is a triterpenoid. http://purl.obolibrary.org/obo/CHEBI_62733 aromatic amide http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound An amide in which the amide linkage is bonded directly to an aromatic system. http://purl.obolibrary.org/obo/CHEBI_62868 hepatoprotective agent http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any compound that is able to prevent damage to the liver. http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from a monosaccharide. http://purl.obolibrary.org/obo/CHEBI_63726 neuroprotective agent http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any compound that can be used for the treatment of neurodegenerative disorders. http://purl.obolibrary.org/obo/CHEBI_64964 EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_35856 lipoxygenase inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 5-lipoxygenase (EC 1.13.11.34). http://purl.obolibrary.org/obo/CHEBI_65023 anti-asthmatic agent http://purl.obolibrary.org/obo/CHEBI_33232 application Any compound that has anti-asthmatic effects. http://purl.obolibrary.org/obo/CHEBI_68495 apoptosis inducer http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. http://purl.obolibrary.org/obo/CHEBI_72010 hydroxyflavan http://purl.obolibrary.org/obo/CHEBI_38672 flavans A member of the class of flavans in which one or more ring hydrogens are replaced by hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals. http://purl.obolibrary.org/obo/CHEBI_75771 mouse metabolite http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). http://purl.obolibrary.org/obo/CHEBI_76902 EC 1.14.11.* (oxidoreductase acting on paired donors, 2-oxoglutarate as one donor, incorporating 1 atom each of oxygen into both donors) inhibitor http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the function of any such enzyme using 2-oxoglutarate as one donor and incorporating one atom each of oxygen into both donors (EC 1.14.11.*). http://purl.obolibrary.org/obo/CHEBI_76924 plant metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. http://purl.obolibrary.org/obo/CHEBI_76971 Escherichia coli metabolite http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. http://purl.obolibrary.org/obo/CHEBI_78298 environmental contaminant http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any minor or unwanted substance introduced into the environment that can have undesired effects. http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity that contains at least one C=C bond. http://purl.obolibrary.org/obo/CHEBI_83925 non-proteinogenic alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids. http://purl.obolibrary.org/obo/CHEBI_88188 drug allergen http://purl.obolibrary.org/obo/CHEBI_23888 drug Any drug which causes the onset of an allergic reaction. http://purl.obolibrary.org/obo/CHEBI_16150 benzoate http://purl.obolibrary.org/obo/CHEBI_22718 benzoates The simplest member of the class of benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1. http://purl.obolibrary.org/obo/CHEBI_23354 coenzyme http://purl.obolibrary.org/obo/CHEBI_23357 cofactor A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. http://purl.obolibrary.org/obo/CHEBI_23858 behenate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A straight-chain saturated fatty acid anion that is the conjugate base of behenic acid, arising from deprotonation of the carboxylic acid group. http://purl.obolibrary.org/obo/CHEBI_26369 psoralens http://purl.obolibrary.org/obo/CHEBI_24128 furanocoumarin A furanocoumarin with a 7H-furo[3,2-g]chromen-7-one skeleton and its substituted derivatives thereof. http://purl.obolibrary.org/obo/CHEBI_26401 purines http://purl.obolibrary.org/obo/CHEBI_35875 imidazopyrimidine A class of imidazopyrimidines that consists of purine and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_27136 triol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A chemical compound containing three hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_30772 butyric acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group. http://purl.obolibrary.org/obo/CHEBI_33654 alicyclic compound http://purl.obolibrary.org/obo/CHEBI_33653 aliphatic compound An aliphatic compound having a carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system. http://purl.obolibrary.org/obo/CHEBI_33655 aromatic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character. http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid containing two carboxy groups. http://purl.obolibrary.org/obo/CHEBI_37808 butane http://purl.obolibrary.org/obo/CHEBI_18310 alkane A straight chain alkane composed of 4 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_59835 hydroxy fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion The conjugate base of any hydroxy fatty acid, formed by deprotonation of the carboxylic acid moiety. http://purl.obolibrary.org/obo/CHEBI_64996 EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_35856 lipoxygenase inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). http://purl.obolibrary.org/obo/CHEBI_65001 EC 3.1.1.3 (triacylglycerol lipase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3). http://purl.obolibrary.org/obo/CHEBI_65256 antimicrobial food preservative http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms. http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite http://purl.obolibrary.org/obo/CHEBI_75787 prokaryotic metabolite Any prokaryotic metabolite produced during a metabolic reaction in bacteria. http://purl.obolibrary.org/obo/CHEBI_76976 bacterial xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria. http://purl.obolibrary.org/obo/CHEBI_79020 alpha,beta-unsaturated monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C#C bond. http://purl.obolibrary.org/obo/CHEBI_84735 algal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae. http://purl.obolibrary.org/obo/CHEBI_25435 mutagen http://purl.obolibrary.org/obo/CHEBI_50902 genotoxin An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution. http://purl.obolibrary.org/obo/CHEBI_27994 luteolin 7-O-beta-D-glucoside http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative A glycosyloxyflavone that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. http://purl.obolibrary.org/obo/CHEBI_28941 behenic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain, C22, long-chain saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_30245 linoleate http://purl.obolibrary.org/obo/CHEBI_25626 octadecadienoate An octadecadienoate with cis- double bonds at the 9- and 12- positions; the conjugate base of linoleic acid. http://purl.obolibrary.org/obo/CHEBI_32361 nonanoate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A medium-chain fatty acid anion that is the conjugate base of nonanoic acid that in methyl ester form has significant nematicidal activity. http://purl.obolibrary.org/obo/CHEBI_33497 transition element molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity containing one or more atoms of a transition element. http://purl.obolibrary.org/obo/CHEBI_33855 arenecarbaldehyde http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde Any aldehyde in which the carbonyl group is attached to an aromatic moiety. http://purl.obolibrary.org/obo/CHEBI_35287 acylcholine http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion A choline ester formed from choline and a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_35442 antiparasitic agent http://purl.obolibrary.org/obo/CHEBI_35441 antiinfective agent A substance used to treat or prevent parasitic infections. http://purl.obolibrary.org/obo/CHEBI_53000 epitope http://purl.obolibrary.org/obo/CHEBI_24432 biological role The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. http://purl.obolibrary.org/obo/CHEBI_62499 methyl-branched fatty acid http://purl.obolibrary.org/obo/CHEBI_35819 branched-chain fatty acid Any branched-chain fatty acid containing methyl branches only. http://purl.obolibrary.org/obo/CHEBI_12777 vitamin A http://purl.obolibrary.org/obo/CHEBI_26537 retinoid A group of fat-soluble retinoids produced via metabolism of provitamin A carotenoids. Vitamin A is involved in immune function, vision, reproduction, and cellular communication. http://purl.obolibrary.org/obo/CHEBI_133150 undecenal http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound A monounsaturated fatty acid aldehyde that is undecanal which has undergone formal dehydrogenation to introduce a double bond at unspecified position. http://purl.obolibrary.org/obo/CHEBI_15355 acetylcholine http://purl.obolibrary.org/obo/CHEBI_35287 acylcholine Actylcholine is an ester of acetic acid and choline, which acts as a neurotransmitter. http://purl.obolibrary.org/obo/CHEBI_15367 all-trans-retinoic acid http://purl.obolibrary.org/obo/CHEBI_26536 retinoic acid A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry. http://purl.obolibrary.org/obo/CHEBI_17336 all-trans-retinol http://purl.obolibrary.org/obo/CHEBI_50211 retinol A retinol in which all four exocyclic double bonds have E- (trans-) geometry. http://purl.obolibrary.org/obo/CHEBI_17522 alditol http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group). http://purl.obolibrary.org/obo/CHEBI_17898 all-trans-retinal http://purl.obolibrary.org/obo/CHEBI_15035 retinal A retinal in which all four exocyclic double bonds have E- (trans-) geometry. http://purl.obolibrary.org/obo/CHEBI_18133 hexose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose). http://purl.obolibrary.org/obo/CHEBI_22469 alpha-terpineol http://purl.obolibrary.org/obo/CHEBI_26876 terpineol A terpineol that is propan-2-ol substituted by a 4-methylcyclohex-3-en-1-yl group at position 2. http://purl.obolibrary.org/obo/CHEBI_24020 fat-soluble vitamin http://purl.obolibrary.org/obo/CHEBI_33229 vitamin Vitamins like A, D, E and K that dissolve in fats and are stored in body tissues. Unlike the water-soluble vitamins, these are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess. http://purl.obolibrary.org/obo/CHEBI_26537 retinoid http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid Oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof. http://purl.obolibrary.org/obo/CHEBI_27689 decanoate http://purl.obolibrary.org/obo/CHEBI_78118 fatty acid anion 10:0 A fatty acid anion 10:0 that is the conjugate base of decanoic acid. http://purl.obolibrary.org/obo/CHEBI_30751 formic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects. http://purl.obolibrary.org/obo/CHEBI_30915 2-oxoglutaric acid http://purl.obolibrary.org/obo/CHEBI_36145 oxo dicarboxylic acid An oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle. http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group. http://purl.obolibrary.org/obo/CHEBI_38070 anti-arrhythmia drug http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. http://purl.obolibrary.org/obo/CHEBI_41139 N,N,N-trimethylglycinium http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion A quaternary ammonium ion in which the substituents on nitrogen are methyl (three) and carboxymethyl. http://purl.obolibrary.org/obo/CHEBI_57560 long-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion A fatty acid anion with a chain length of C13 or greater. http://purl.obolibrary.org/obo/CHEBI_61115 EC 3.5.1.98 (histone deacetylase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98). http://purl.obolibrary.org/obo/CHEBI_63410 all-trans-retinyl ester http://purl.obolibrary.org/obo/CHEBI_16179 retinyl ester A retintinyl ester in which all double bonds of the retinyl side-chain have trans-configuration. http://purl.obolibrary.org/obo/CHEBI_16119 shikimic acid http://purl.obolibrary.org/obo/CHEBI_79020 alpha,beta-unsaturated monocarboxylic acid A cyclohexenecarboxylic acid that is cyclohex-1-ene-1-carboxylic acid substituted by hydroxy groups at positions 3, 4 and 5 (the 3R,4S,5R stereoisomer). It is an intermediate metabolite in plants and microorganisms. http://purl.obolibrary.org/obo/CHEBI_17 (+)-Cassythicine http://purl.obolibrary.org/obo/CHEBI_24921 isoquinoline alkaloid An isoquinoline alkaloid that has formula C19H19NO4. http://purl.obolibrary.org/obo/CHEBI_17053 L-aspartic acid http://purl.obolibrary.org/obo/CHEBI_22658 aspartate family amino acid The L-enantiomer of aspartic acid. http://purl.obolibrary.org/obo/CHEBI_17364 D-aspartic acid http://purl.obolibrary.org/obo/CHEBI_16733 D-alpha-amino acid The D-enantiomer of aspartic acid. http://purl.obolibrary.org/obo/CHEBI_17521 (-)-quinic acid http://purl.obolibrary.org/obo/CHEBI_26493 quinic acid The (-)-enantiomer of quinic acid. http://purl.obolibrary.org/obo/CHEBI_20067 3-hydroxybutyric acid http://purl.obolibrary.org/obo/CHEBI_78954 (omega-1)-hydroxy fatty acid A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics. http://purl.obolibrary.org/obo/CHEBI_22658 aspartate family amino acid http://purl.obolibrary.org/obo/CHEBI_83813 proteinogenic amino acid An L-alpha-amino acid which is L-aspartic acid or any of the essential amino acids biosynthesised from it (asparagine, lysine, methionine, threonine and isoleucine). A closed class. http://purl.obolibrary.org/obo/CHEBI_22676 auxin http://purl.obolibrary.org/obo/CHEBI_37848 plant hormone Any of a group of compounds, both naturally occurring and synthetic, that induce cell elongation in plant stems (from Greek alphaupsilonxialphanuomega, "to grow"). http://purl.obolibrary.org/obo/CHEBI_22698 benzaldehydes http://purl.obolibrary.org/obo/CHEBI_33855 arenecarbaldehyde Any arenecarbaldehyde that consists of a formyl substituted benzene ring and its substituted derivatives thereof. http://purl.obolibrary.org/obo/CHEBI_23982 ethanols http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol Any primary alcohol based on an ethanol skeleton. http://purl.obolibrary.org/obo/CHEBI_24669 hydroxy carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid with at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_24996 lactate http://purl.obolibrary.org/obo/CHEBI_36059 hydroxy monocarboxylic acid anion A hydroxy monocarboxylic acid anion that is the conjugate base of lactic acid, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_25388 monohydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_24675 hydroxybenzoate A hydroxybenzoate carrying a single hydroxy substituent at unspecified position. http://purl.obolibrary.org/obo/CHEBI_25608 nucleoside phosphate http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates. http://purl.obolibrary.org/obo/CHEBI_25883 pentahydroxyflavone http://purl.obolibrary.org/obo/CHEBI_24698 hydroxyflavone A hydroxyflavone substituted by five hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_26078 phosphoric acid http://purl.obolibrary.org/obo/CHEBI_59698 phosphoric acids A phosphorus oxoacid that consits of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. http://purl.obolibrary.org/obo/CHEBI_26130 biological pigment http://purl.obolibrary.org/obo/CHEBI_52208 biophysical role An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light. http://purl.obolibrary.org/obo/CHEBI_26199 polyprenol http://purl.obolibrary.org/obo/CHEBI_26244 prenols Any member of the class of prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units. http://purl.obolibrary.org/obo/CHEBI_26244 prenols http://purl.obolibrary.org/obo/CHEBI_30879 alcohol Any alcohol possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of one or more isoprene units (biogenetic precursors of the isoprenoids). http://purl.obolibrary.org/obo/CHEBI_26271 proline http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2. http://purl.obolibrary.org/obo/CHEBI_26493 quinic acid http://purl.obolibrary.org/obo/CHEBI_36123 cyclitol carboxylic acid A cyclitol carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_26986 threonine http://purl.obolibrary.org/obo/CHEBI_38263 2-amino-3-hydroxybutanoic acid An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 1-hydroxyethyl group. http://purl.obolibrary.org/obo/CHEBI_27266 valine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group. http://purl.obolibrary.org/obo/CHEBI_27570 histidine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. http://purl.obolibrary.org/obo/CHEBI_28044 phenylalanine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group. http://purl.obolibrary.org/obo/CHEBI_28938 ammonium http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion An onium cation obtained by protonation of ammonia. http://purl.obolibrary.org/obo/CHEBI_29016 arginine http://purl.obolibrary.org/obo/CHEBI_24436 guanidines An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. http://purl.obolibrary.org/obo/CHEBI_29337 azanide http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion A nitrogen hydride that has formula H2N. http://purl.obolibrary.org/obo/CHEBI_29993 L-aspartate(2-) http://purl.obolibrary.org/obo/CHEBI_29995 aspartate(2-) An aspartate(2-) that is the conjugate base of L-aspartate(1-). http://purl.obolibrary.org/obo/CHEBI_30778 gallic acid http://purl.obolibrary.org/obo/CHEBI_27115 trihydroxybenzoic acid A trihydroxybenzoic acid in which the hydroxy groups are at positions 3, 4, and 5. http://purl.obolibrary.org/obo/CHEBI_30795 malonate(1-) http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion A dicarboxylic acid monoanion that has formula C3H3O4. http://purl.obolibrary.org/obo/CHEBI_30816 vanillic acid http://purl.obolibrary.org/obo/CHEBI_25389 monohydroxybenzoic acid A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3. http://purl.obolibrary.org/obo/CHEBI_30916 2-oxoglutarate(1-) http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion A dicarboxylic acid monoanion resulting from selective deprotonation of the 1-carboxy group of 2-oxoglutaric acid. http://purl.obolibrary.org/obo/CHEBI_32439 alaninate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that is the conjugate base of alanine, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32440 alaninium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that is the conjugate acid of alanine. http://purl.obolibrary.org/obo/CHEBI_32644 methioninate http://purl.obolibrary.org/obo/CHEBI_63470 sulfur-containing amino-acid anion A sulfur-containing amino-acid anion that is the conjugate base of methionine, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32646 methioninium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation A sulfur-containing amino-acid anion that is the conjugate acid of methionine, arising from protonation of the amino group. http://purl.obolibrary.org/obo/CHEBI_32820 L-threoninate http://purl.obolibrary.org/obo/CHEBI_32832 threoninate An L-alpha-amino acid anion that is the conjugate base of L-threonine, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32822 L-threoninium http://purl.obolibrary.org/obo/CHEBI_32833 threoninium The L-enantiomer of threoninium. http://purl.obolibrary.org/obo/CHEBI_32827 D-threoninate http://purl.obolibrary.org/obo/CHEBI_32832 threoninate The D-enantiomer of threoninate. http://purl.obolibrary.org/obo/CHEBI_32828 D-threoninium http://purl.obolibrary.org/obo/CHEBI_32833 threoninium The D-enantiomer of threoninium. http://purl.obolibrary.org/obo/CHEBI_33256 primary amide http://purl.obolibrary.org/obo/CHEBI_32988 amide A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/CHEBI_33287 fertilizer http://purl.obolibrary.org/obo/CHEBI_33286 agrochemical A fertilizer is any substance that is added to soil or water to assist the growth of plants. http://purl.obolibrary.org/obo/CHEBI_33457 phosphorus oxoacid http://purl.obolibrary.org/obo/CHEBI_33408 pnictogen oxoacid A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons. http://purl.obolibrary.org/obo/CHEBI_33576 sulfur-containing carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid having a sulfur substituent. http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CHEBI_33942 ribose http://purl.obolibrary.org/obo/CHEBI_33916 aldopentose Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature. http://purl.obolibrary.org/obo/CHEBI_35008 tetralin http://purl.obolibrary.org/obo/CHEBI_35428 ortho-fused bicyclic hydrocarbon An ortho-fused bicyclic hydrocarbon that is 1,2,3,4-tetrahydro derivative of naphthalene. http://purl.obolibrary.org/obo/CHEBI_35589 9H-purine http://purl.obolibrary.org/obo/CHEBI_35584 purine The 9H-tautomer of purine. http://purl.obolibrary.org/obo/CHEBI_35679 antilipemic drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter. http://purl.obolibrary.org/obo/CHEBI_35808 citrate(2-) http://purl.obolibrary.org/obo/CHEBI_36300 tricarboxylic acid dianion A tricarboxylic acid dianion obtained by deprotonation of two of the three carboxy groups of citric acid. http://purl.obolibrary.org/obo/CHEBI_35821 anticholesteremic drug http://purl.obolibrary.org/obo/CHEBI_35679 antilipemic drug A substance used to lower plasma cholesterol levels. http://purl.obolibrary.org/obo/CHEBI_36009 omega-6 fatty acid http://purl.obolibrary.org/obo/CHEBI_59549 essential fatty acid A family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the n-6 position, i.e., the sixth bond from the methyl end of the fatty acid. http://purl.obolibrary.org/obo/CHEBI_36043 antimicrobial drug http://purl.obolibrary.org/obo/CHEBI_35441 antiinfective agent A drug used to treat or prevent microbial infections. http://purl.obolibrary.org/obo/CHEBI_37604 cis-octadec-9-ene http://purl.obolibrary.org/obo/CHEBI_37605 octadec-9-ene An octadec-9-ene that has formula C18H36. http://purl.obolibrary.org/obo/CHEBI_37631 beta-L-glucose http://purl.obolibrary.org/obo/CHEBI_37627 L-glucopyranose A L-glucopyranose with a beta-configuration at the anomeric position. http://purl.obolibrary.org/obo/CHEBI_37848 plant hormone http://purl.obolibrary.org/obo/CHEBI_24621 hormone A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds. http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid http://purl.obolibrary.org/obo/CHEBI_59202 straight-chain fatty acid Any saturated fatty acid lacking a side-chain. http://purl.obolibrary.org/obo/CHEBI_39474 polyazaalkane http://purl.obolibrary.org/obo/CHEBI_46686 azaalkane Any azaalkane in which two or more carbons in the chain are replaced by nitrogen. http://purl.obolibrary.org/obo/CHEBI_4167 D-glucopyranose http://purl.obolibrary.org/obo/CHEBI_17634 D-glucose A glucopyranose having D-configuration. http://purl.obolibrary.org/obo/CHEBI_422 (S)-lactic acid http://purl.obolibrary.org/obo/CHEBI_78320 2-hydroxypropanoic acid An optically active form of lactic acid having (S)-configuration. http://purl.obolibrary.org/obo/CHEBI_42223 emodin http://purl.obolibrary.org/obo/CHEBI_37488 trihydroxyanthraquinone A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by hydroxy groups at positions 1, 3, and 8 and by a methyl group at position 6. It is present in the roots and barks of numerous plants (particularly rhubarb and buckthorn), moulds, and lichens. It is an active ingredient of various Chinese herbs. http://purl.obolibrary.org/obo/CHEBI_456216 ADP(3-) http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion An organophosphate oxoanion that is the trianion of adenosine 5'-diphosphate arising from deprotonation of all three OH groups of the diphosphate; major species present at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_46787 solvent http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A liquid that can dissolve other substances (solutes) without any change in their chemical composition. http://purl.obolibrary.org/obo/CHEBI_48024 3'-hydroxyflavanones http://purl.obolibrary.org/obo/CHEBI_24697 hydroxyflavanone Any hydroxyflavanone with a hydroxy substituent at position 3' of the phenyl ring. http://purl.obolibrary.org/obo/CHEBI_48218 antiseptic drug http://purl.obolibrary.org/obo/CHEBI_35441 antiinfective agent A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body). http://purl.obolibrary.org/obo/CHEBI_48219 disinfectant http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity. http://purl.obolibrary.org/obo/CHEBI_48299 butane-1,2,3,4-tetrol http://purl.obolibrary.org/obo/CHEBI_33729 tetritol A tetritol that is butane substituted by hydroxy groups at positions 1, 2, 3 and 4. http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent http://purl.obolibrary.org/obo/CHEBI_46787 solvent A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds. http://purl.obolibrary.org/obo/CHEBI_50248 hematologic agent http://purl.obolibrary.org/obo/CHEBI_23888 drug Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. http://purl.obolibrary.org/obo/CHEBI_50276 EC 5.99.1.2 (DNA topoisomerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_70727 topoisomerase inhibitor A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. http://purl.obolibrary.org/obo/CHEBI_50584 alkyl alcohol http://purl.obolibrary.org/obo/CHEBI_2571 aliphatic alcohol An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position. http://purl.obolibrary.org/obo/CHEBI_50847 immunological adjuvant http://purl.obolibrary.org/obo/CHEBI_50846 immunomodulator A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. http://purl.obolibrary.org/obo/CHEBI_52092 ethoxide http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the conjugate base of ethanol. http://purl.obolibrary.org/obo/CHEBI_52267 7-hydroxyflavonol http://purl.obolibrary.org/obo/CHEBI_28802 flavonols Any flavonol carrying a 7-hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_57545 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion A flavonoid oxoanion that is the conjugate base of luteolin, arising from selective deprotonation of the 7-hydroxy group. http://purl.obolibrary.org/obo/CHEBI_57644 chlorogenate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of chlorogenic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57694 quercetin-7-olate http://purl.obolibrary.org/obo/CHEBI_58588 flavonol oxoanion Conjugate base of quercetin arising from selective deprotonation of the 7-hydroxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57757 D-threonine zwitterion http://purl.obolibrary.org/obo/CHEBI_59871 D-alpha-amino acid zwitterion A D-alpha-amino acid zwitterion that is D-threonine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57770 trans-caffeate http://purl.obolibrary.org/obo/CHEBI_36059 hydroxy monocarboxylic acid anion The conjugate base of trans-caffeic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57834 spermidine(3+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion An ammonium ion that is the trication of spermidine, formed by protonation at all three nitrogens. http://purl.obolibrary.org/obo/CHEBI_57867 nucleoside 5'-phosphate dianion http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion The conjugate base of a nucleoside 5'-phosphate. http://purl.obolibrary.org/obo/CHEBI_57887 tryptaminium http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion An ammonium ion that is the conjugate acid of tryptamine arising from protonation of the primary amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57926 L-threonine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion Zwitterionic form of L-threonine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57930 nucleoside diphosphate(3-) http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion Trianion of nucleoside diiphosphate arising from deprotonation of all three free OH groups of the diphosphate; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion lacking a carbon side-chain. http://purl.obolibrary.org/obo/CHEBI_59871 D-alpha-amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group. http://purl.obolibrary.org/obo/CHEBI_59888 gamma-aminobutyric acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion Zwitterionic form of gamma-aminobutyric acid having an anionic carboxy group and a protonated amino group. http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation http://purl.obolibrary.org/obo/CHEBI_64641 divalent inorganic cation A metal cation with a valence of two. http://purl.obolibrary.org/obo/CHEBI_60895 D-alpha-amino acid anion http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion Any alpha-amino acid anion in which the parent amino acid has D-configuration. http://purl.obolibrary.org/obo/CHEBI_62215 allelochemical http://purl.obolibrary.org/obo/CHEBI_25212 metabolite A class of secondary metabolites developed by many plants to influence the behaviour, growth or survival of herbivores, and thus acting as a defence against herbivory. http://purl.obolibrary.org/obo/CHEBI_64018 protein kinase C agonist http://purl.obolibrary.org/obo/CHEBI_64106 protein kinase agonist An agonist that selectively binds to and activates a protein kinase C receptor http://purl.obolibrary.org/obo/CHEBI_64365 aralkylamino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound An organic amino compound in which an aminoalkyl group is linked to an arene. http://purl.obolibrary.org/obo/CHEBI_64558 methionine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of methionine; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_66916 alanine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of alanine; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_73181 EC 1.11.1.11 (L-ascorbate peroxidase) inhibitors http://purl.obolibrary.org/obo/CHEBI_75381 EC 1.11.1.* (peroxidases) inhibitor An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11). http://purl.obolibrary.org/obo/CHEBI_77020 EC 1.10.99.2 [ribosyldihydronicotinamide dehydrogenase (quinone)] inhibitor http://purl.obolibrary.org/obo/CHEBI_77019 EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor An EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor that interferes with the action of ribosyldihydronicotinamide dehydrogenase (quinone), EC 1.10.99.2. http://purl.obolibrary.org/obo/CHEBI_77119 EC 1.1.1.189 (prostaglandin-E2 9-reductase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76835 EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of prostaglandin-E2 9-reductase (EC 1.1.1.189). http://purl.obolibrary.org/obo/CHEBI_77182 food colouring http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199). http://purl.obolibrary.org/obo/CHEBI_77966 food stabiliser http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that is used to preserve the structure of food. http://purl.obolibrary.org/obo/CHEBI_77970 food thickening agent http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that is used to increase the viscosity of foodstuffs. http://purl.obolibrary.org/obo/CHEBI_78017 food propellant http://purl.obolibrary.org/obo/CHEBI_76414 propellant A propellant that is used to expel foods from an aerosol container. http://purl.obolibrary.org/obo/CHEBI_78116 fatty acid anion 6:0 http://purl.obolibrary.org/obo/CHEBI_59558 medium-chain fatty acid anion Any saturated fatty acid anion containing 6 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78295 food component http://purl.obolibrary.org/obo/CHEBI_52211 physiological role Any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants. http://purl.obolibrary.org/obo/CHEBI_78320 2-hydroxypropanoic acid http://purl.obolibrary.org/obo/CHEBI_49302 2-hydroxy monocarboxylic acid A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_78433 refrigerant http://purl.obolibrary.org/obo/CHEBI_33232 application A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure. http://purl.obolibrary.org/obo/CHEBI_78444 EC 3.1.1.1 (carboxylesterase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 ). http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. http://purl.obolibrary.org/obo/CHEBI_79387 trivalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of three. http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of one. http://purl.obolibrary.org/obo/CHEBI_83038 Daphnia galeata metabolite http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite A Daphnia metabolite produced by the species Daphnia galeata. http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane http://purl.obolibrary.org/obo/CHEBI_18310 alkane Any alkane having a chain length of at least 13 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_83813 proteinogenic amino acid http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration. http://purl.obolibrary.org/obo/CHEBI_84264 EC 3.5.1.19 (nicotinamidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19). http://purl.obolibrary.org/obo/CHEBI_85046 skin lightening agent http://purl.obolibrary.org/obo/CHEBI_64857 cosmetic Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin. http://purl.obolibrary.org/obo/CHEBI_86494 botanical anti-fungal agent http://purl.obolibrary.org/obo/CHEBI_33285 heteroorganic entity Heteroorganic entities that are plant metabolites which have significant antifungal properties. http://purl.obolibrary.org/obo/CHEBI_87518 ADP(2-) http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion An organophosphate oxoanion obtained by deprotonation of two of the three diphosphate OH groups of adenosine 5'-diphosphate. http://purl.obolibrary.org/obo/CHEBI_17964 pipecolic acid http://purl.obolibrary.org/obo/CHEBI_26148 piperidinemonocarboxylic acid A piperidinemonocarboxylic acid in which the carboxy group is located at position C-2. http://purl.obolibrary.org/obo/CHEBI_1879 2-(4-hydroxyphenyl)ethanol http://purl.obolibrary.org/obo/CHEBI_33853 phenols A phenol substituted at position 4 by a 2-hydroxyethyl group. http://purl.obolibrary.org/obo/CHEBI_19591 2-hexenal http://purl.obolibrary.org/obo/CHEBI_24578 hexenal A hexenal having the double bond at the 2-position. http://purl.obolibrary.org/obo/CHEBI_22695 base http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base). http://purl.obolibrary.org/obo/CHEBI_22958 butenedioic acid http://purl.obolibrary.org/obo/CHEBI_66873 C4-dicarboxylic acid A C4-dicarboxylic acid that has formula C4H4O4. http://purl.obolibrary.org/obo/CHEBI_24221 3,7-dimethylocta-2,6-dien-1-ol http://purl.obolibrary.org/obo/CHEBI_26199 polyprenol An octadienol that has formula C10H18O. http://purl.obolibrary.org/obo/CHEBI_24329 glutarate http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of glutaric acid. http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent A compound consisting of carbon and hydrogen only. http://purl.obolibrary.org/obo/CHEBI_24898 isoleucine http://purl.obolibrary.org/obo/CHEBI_38264 2-amino-3-methylpentanoic acid A 2-amino-3-methylpentanoic acid having either (2R,3R)- or (2S,3S)-configuration. http://purl.obolibrary.org/obo/CHEBI_25627 octadecadienoic acid http://purl.obolibrary.org/obo/CHEBI_26208 polyunsaturated fatty acid Any straight-chain, C18 polyunsaturated fatty acid having two C=C double bonds. http://purl.obolibrary.org/obo/CHEBI_27616 psoralen http://purl.obolibrary.org/obo/CHEBI_26369 psoralens The simplest member of the class of psoralens that is 7H-furo[3,2-g]chromene having a keto group at position 7. It has been found in plants like Psoralea corylifolia and Ficus salicifolia. http://purl.obolibrary.org/obo/CHEBI_27961 1,8-cineole http://purl.obolibrary.org/obo/CHEBI_23243 cineole A cineole that has formula C10H18O. http://purl.obolibrary.org/obo/CHEBI_28591 guaiacol http://purl.obolibrary.org/obo/CHEBI_33853 phenols A monomethoxybenzene that consists of phenol with a methoxy substituent at the ortho position. http://purl.obolibrary.org/obo/CHEBI_28972 (R)-propane-1,2-diol http://purl.obolibrary.org/obo/CHEBI_16997 propane-1,2-diol A propane-1,2-diol that has formula C3H8O2. http://purl.obolibrary.org/obo/CHEBI_29002 (S)-propane-1,2-diol http://purl.obolibrary.org/obo/CHEBI_16997 propane-1,2-diol A propane-1,2-diol that has formula C3H8O2. http://purl.obolibrary.org/obo/CHEBI_30632 loganic acid http://purl.obolibrary.org/obo/CHEBI_38606 cyclopentapyran A cyclopentapyran that is 1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid substituted at positions 1, 6 and 7 by beta-D-glucosyloxy, hydroxy and methyl groups respectively http://purl.obolibrary.org/obo/CHEBI_30800 phthalate(1-) http://purl.obolibrary.org/obo/CHEBI_26092 phthalate A phthalate that is the conjugate base of phthalic acid. http://purl.obolibrary.org/obo/CHEBI_32845 serinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that is the conjugate base of serine. http://purl.obolibrary.org/obo/CHEBI_32846 serinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that is the conjugate acid of serine. http://purl.obolibrary.org/obo/CHEBI_33227 (E)-cinnamyl alcohol http://purl.obolibrary.org/obo/CHEBI_17177 cinnamyl alcohol The E (trans) stereoisomer of cinnamyl alcohol. http://purl.obolibrary.org/obo/CHEBI_33292 fuel http://purl.obolibrary.org/obo/CHEBI_33232 application An energy-rich substance that can be transformed with release of usable energy. http://purl.obolibrary.org/obo/CHEBI_33653 aliphatic compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds. http://purl.obolibrary.org/obo/CHEBI_33694 biomacromolecule http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A macromolecule formed by a living organism. http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose http://purl.obolibrary.org/obo/CHEBI_18133 hexose A hexose with a (potential) aldehyde group at one end. http://purl.obolibrary.org/obo/CHEBI_35243 serine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amnio group of serine. http://purl.obolibrary.org/obo/CHEBI_35492 cystine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion that is the tautomer of cystine. http://purl.obolibrary.org/obo/CHEBI_35518 campestane http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent A steroid fundamental parent that has formula C28H50. http://purl.obolibrary.org/obo/CHEBI_35544 EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76840 EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. http://purl.obolibrary.org/obo/CHEBI_35584 purine http://purl.obolibrary.org/obo/CHEBI_35570 mancude organic heterobicyclic parent A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines. http://purl.obolibrary.org/obo/CHEBI_35586 1H-purine http://purl.obolibrary.org/obo/CHEBI_35584 purine The 1H-tautomer of purine. http://purl.obolibrary.org/obo/CHEBI_35588 3H-purine http://purl.obolibrary.org/obo/CHEBI_35584 purine The 3H-tautomer of purine. http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n. http://purl.obolibrary.org/obo/CHEBI_35649 morphinan http://purl.obolibrary.org/obo/CHEBI_38515 isoquinoline alkaloid fundamental parent An isoquinoline alkaloid fundamental parent that has formula C16H21N. http://purl.obolibrary.org/obo/CHEBI_35710 pinane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A monoterpene that is bicyclo[3.1.1]heptane substituted by methyl groups at positions 2, 6 and 6. http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion http://purl.obolibrary.org/obo/CHEBI_33461 phosphorus oxoanion A phosphorus oxoanion that is the conjugate base of phosphoric acid. http://purl.obolibrary.org/obo/CHEBI_35907 glutarate(1-) http://purl.obolibrary.org/obo/CHEBI_24329 glutarate A dicarboxylic acid monoanion that is the conjugate base of glutaric acid. http://purl.obolibrary.org/obo/CHEBI_36110 pipecolate http://purl.obolibrary.org/obo/CHEBI_36109 piperidinecarboxylate A piperidinecarboxylate that is the conjugate base of pipecolic acid. http://purl.obolibrary.org/obo/CHEBI_36124 (+)-quinic acid http://purl.obolibrary.org/obo/CHEBI_26493 quinic acid The (+)-enantiomer of quinic acid. http://purl.obolibrary.org/obo/CHEBI_38637 tyrosine kinase inhibitor http://purl.obolibrary.org/obo/CHEBI_37699 protein kinase inhibitor Any protein kinase inhibitor that interferes with the action of tyrosine kinase. http://purl.obolibrary.org/obo/CHEBI_39127 magnesium cation http://purl.obolibrary.org/obo/CHEBI_33513 alkaline earth cation Any magnesium ion that is positively charged. http://purl.obolibrary.org/obo/CHEBI_41609 carbonate http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion A carbon oxoanion that has formula 60.00890. http://purl.obolibrary.org/obo/CHEBI_4194 D-hexose http://purl.obolibrary.org/obo/CHEBI_18133 hexose A hexose that has D-configuration at position 5. http://purl.obolibrary.org/obo/CHEBI_42639 gamma-butyrolactone http://purl.obolibrary.org/obo/CHEBI_22950 butan-4-olide A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2. http://purl.obolibrary.org/obo/CHEBI_43254 (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone A pyrimidone that has formula C4H6N2O2. http://purl.obolibrary.org/obo/CHEBI_43474 hydrogenphosphate http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion A phosphate ion that is the conjugate base of dihydrogenphosphate. http://purl.obolibrary.org/obo/CHEBI_47016 tetrahydrofuranone http://purl.obolibrary.org/obo/CHEBI_26912 oxolanes Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring. http://purl.obolibrary.org/obo/CHEBI_47867 indicator http://purl.obolibrary.org/obo/CHEBI_33232 application Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc. http://purl.obolibrary.org/obo/CHEBI_48873 cholinergic antagonist http://purl.obolibrary.org/obo/CHEBI_38323 cholinergic drug Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. http://purl.obolibrary.org/obo/CHEBI_49000 2-phenylethanol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A primary alcohol that is ethanol substituted by a phenyl group at position 2. http://purl.obolibrary.org/obo/CHEBI_50201 (R)-naringenin http://purl.obolibrary.org/obo/CHEBI_50202 naringenin The (R)-enantiomer of naringenin. http://purl.obolibrary.org/obo/CHEBI_50524 catecholate(1-) http://purl.obolibrary.org/obo/CHEBI_50525 phenolate anion A phenolate anion that is the conjugate base of catechol. http://purl.obolibrary.org/obo/CHEBI_50684 cross-linking reagent http://purl.obolibrary.org/obo/CHEBI_33893 reagent A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified. http://purl.obolibrary.org/obo/CHEBI_50846 immunomodulator http://purl.obolibrary.org/obo/CHEBI_23888 drug Biologically active substance whose activity affects or plays a role in the functioning of the immune system. http://purl.obolibrary.org/obo/CHEBI_50908 hepatotoxic agent http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. http://purl.obolibrary.org/obo/CHEBI_52058 5-hydroxyfurocoumarin http://purl.obolibrary.org/obo/CHEBI_24128 furanocoumarin A furanocoumarin which bears a hydroxy group at position 5. http://purl.obolibrary.org/obo/CHEBI_52090 methoxide http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the conjugate base of methanol. http://purl.obolibrary.org/obo/CHEBI_55323 antidiarrhoeal drug http://purl.obolibrary.org/obo/CHEBI_55324 gastrointestinal drug Any drug found useful in the symptomatic treatment of diarrhoea. http://purl.obolibrary.org/obo/CHEBI_58043 nucleoside 5'-monophosphate(2-) http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion The dianion of a nucleoside monophosphate: major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58061 salutaridinium(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion The conjugate acid of salutaridine; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58192 quercitrin-7-olate http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion Conjugate base of quercitrin arising from selective deprotonation of the 7-hydroxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58292 (S)-naringenin(1-) http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion A flavonoid oxoanion that is the conjugate base of (S)-naringenin, arising from selective deprotonation of the 7-hydroxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58333 isoorientin(1-) http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion A flavonoid oxoanion that is the conjugate base of isoorientin, arising from selective deprotonation of the 7-hydroxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58432 histaminium http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion An ammonium ion that is the conjugate acid of histamine protonated on the side-chain nitrogen. http://purl.obolibrary.org/obo/CHEBI_58447 isovitexin-7-olate http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion The 7-oxoanion of isovitexin. http://purl.obolibrary.org/obo/CHEBI_58470 apigenin-7-olate http://purl.obolibrary.org/obo/CHEBI_25696 organic anion The 7-oxoanion of apigenin http://purl.obolibrary.org/obo/CHEBI_58896 2-hydroxy carboxylate http://purl.obolibrary.org/obo/CHEBI_36059 hydroxy monocarboxylic acid anion The conjugate base of a 2-hydroxy carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_61296 adenyl ribonucleotide http://purl.obolibrary.org/obo/CHEBI_61293 adenyl nucleotide A purine riboncleotide where adenine is the purine. http://purl.obolibrary.org/obo/CHEBI_62803 fuel additive http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any additive that enhances the efficiency of fuel. http://purl.obolibrary.org/obo/CHEBI_62873 odorant receptor agonist http://purl.obolibrary.org/obo/CHEBI_48705 agonist An agonist that selectively binds to and activates an odorant receptor. http://purl.obolibrary.org/obo/CHEBI_63047 food emulsifier http://purl.obolibrary.org/obo/CHEBI_63046 emulsifier A food additive used to form or maintain a uniform emulsion of two (or more) phases in a food. http://purl.obolibrary.org/obo/CHEBI_64477 monolignol http://purl.obolibrary.org/obo/CHEBI_76924 plant metabolite A metabolite of plant origin (phytochemical) which acts as a source material for biosynthesis of both lignans and lignin. http://purl.obolibrary.org/obo/CHEBI_64763 EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor http://purl.obolibrary.org/obo/CHEBI_50218 EC 3.1.4.* (phosphoric diester hydrolase) inhibitor An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C (EC 3.1.4.11). http://purl.obolibrary.org/obo/CHEBI_64951 anti-HBV agent http://purl.obolibrary.org/obo/CHEBI_22587 antiviral agent An antiviral agent that destroys or inhibits the replication of the hepatitis B virus. http://purl.obolibrary.org/obo/CHEBI_67195 gap junctional intercellular communication inhibitor http://purl.obolibrary.org/obo/CHEBI_35222 inhibitor An inhibitor that interferes with the process of gap junctional intercellular communication. http://purl.obolibrary.org/obo/CHEBI_68837 pectate http://purl.obolibrary.org/obo/CHEBI_61469 polyanionic polymer An polyanionic polymer obtained by global deprotonation of the carboxy groups of pectin. http://purl.obolibrary.org/obo/CHEBI_73136 EC 1.1.1.184 [carbonyl reductase (NADPH)] inhibitor http://purl.obolibrary.org/obo/CHEBI_76835 EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of carbonyl reductase (NADPH), EC 1.1.1.184. http://purl.obolibrary.org/obo/CHEBI_76424 quercetin O-glycoside http://purl.obolibrary.org/obo/CHEBI_50018 glycosyloxyflavone Any glycosyloxyflavone that is an O-glycosylated derivative of quercetin. http://purl.obolibrary.org/obo/CHEBI_77035 expectorant http://purl.obolibrary.org/obo/CHEBI_23888 drug Compounds that are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing. Compare with mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration, and antitussives, which suppress the cough reflex. http://purl.obolibrary.org/obo/CHEBI_77118 EC 3.5.5.1 (nitrilase) inhhibitor http://purl.obolibrary.org/obo/CHEBI_77117 EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor An EC 3.5.5.* (hydrolase acting on C-N bonds in nitriles) inhibitor that interferes with the action of nitrilase (EC 3.5.5.1). http://purl.obolibrary.org/obo/CHEBI_77688 formononetin(1-) http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion A flavonoid oxoanion that is the conjugate base of formononetin, obtained by deprotonation of the 7-hydroxy group. Major microspecies at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_77728 bergaptol(1-) http://purl.obolibrary.org/obo/CHEBI_50525 phenolate anion A phenolate anion that is the conjugate base of bergaptol, obtained by deprotonation of the phenolic hydroxy substituent. Major microspecies at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_78016 food gelling agent http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that enhances the texture of a foodstuff by gel formation. http://purl.obolibrary.org/obo/CHEBI_78113 fatty acid anion 3:0 http://purl.obolibrary.org/obo/CHEBI_58951 short-chain fatty acid anion Any saturated fatty acid anion containing 3 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78115 fatty acid anion 4:0 http://purl.obolibrary.org/obo/CHEBI_58951 short-chain fatty acid anion Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78119 fatty acid anion 12:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 12 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_79056 plasticiser http://purl.obolibrary.org/obo/CHEBI_33232 application Any compound that is used as an additive to increase the plasticity or fluidity of a substance, particularly but not exclusively to synthetic polymers. http://purl.obolibrary.org/obo/CHEBI_83821 amino acid derivative http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues. http://purl.obolibrary.org/obo/CHEBI_90 (-)-epicatechin http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol A catechin with (2R,3R)-configuration. http://purl.obolibrary.org/obo/CHEBI_30512 silver atom http://purl.obolibrary.org/obo/CHEBI_33366 copper group element atom A copper group element atom that has formula Ag. http://purl.obolibrary.org/obo/CHEBI_30582 silicon(1+) http://purl.obolibrary.org/obo/CHEBI_37763 elemental silicon An elemental silicon that has formula Si. http://purl.obolibrary.org/obo/CHEBI_3063 Berbamine http://purl.obolibrary.org/obo/CHEBI_24922 isoquinolines A bisbenzylisoquinoline alkaloid that has formula C37H40N2O6. http://purl.obolibrary.org/obo/CHEBI_3086 betulin http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-hydroxymethyl substituents. http://purl.obolibrary.org/obo/CHEBI_3087 betulinic acid http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is lupane having a double bond at position 20(29) as well as 3beta-hydroxy and 28-carboxy substituents. It is found in the bark and other plant parts of several species of plants including Syzygium claviflorum. It exhibits anti-HIV, antimalarial, antineoplastic and anti-inflammatory properties. http://purl.obolibrary.org/obo/CHEBI_31002 octacosanoate http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion A very long straight-chain saturated fatty acid anion and the conjugate base of octacosanoic acid (montanic acid), arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_31003 melissic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C30, very long straight-chain, saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_31004 melissate http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion A very long straight-chain saturated fatty acid anion that is the conjugate base of melissic acid, arising from deprotonation of the carboxylic acid group. http://purl.obolibrary.org/obo/CHEBI_31013 cerotate http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion The conjugate base of cerotic acid. http://purl.obolibrary.org/obo/CHEBI_3151 Bornyl acetate http://purl.obolibrary.org/obo/CHEBI_25409 monoterpenoid A monoterpenoid that has formula C12H20O2. http://purl.obolibrary.org/obo/CHEBI_32154 stearyl alcohol http://purl.obolibrary.org/obo/CHEBI_78138 fatty alcohol 18:0 A fatty alcohol consisting of a hydroxy function at C-1 of an unbranched saturated chain of 18 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_35804 citrate(1-) http://purl.obolibrary.org/obo/CHEBI_36299 tricarboxylic acid monoanion A tricarboxylic acid monoanion that is the conjugate base of citric acid, obtained by deprotonation of one of the three carboxy groups. http://purl.obolibrary.org/obo/CHEBI_36485 lupane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A triterpene that has formula C30H52. http://purl.obolibrary.org/obo/CHEBI_36523 humulane http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A terpenoid fundamental parent that has formula C15H30. http://purl.obolibrary.org/obo/CHEBI_37606 octadecene http://purl.obolibrary.org/obo/CHEBI_32878 alkene An alkene that is octadecane containing one double bond at unspecified position. http://purl.obolibrary.org/obo/CHEBI_42255 (-)-epigallocatechin http://purl.obolibrary.org/obo/CHEBI_71224 flavan-3,3',4',5,5',7-hexol A flavan-3,3',4',5,5',7-hexol having (2R,3R)-configuration. http://purl.obolibrary.org/obo/CHEBI_49414 molybdenum(4+) http://purl.obolibrary.org/obo/CHEBI_37239 molybdenum cation A molybdenum cation that has formula 95.94000. http://purl.obolibrary.org/obo/CHEBI_50103 excitatory amino acid agonist http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent An agent that binds to and activates excitatory amino acid receptors. http://purl.obolibrary.org/obo/CHEBI_68330 gallocatechin http://purl.obolibrary.org/obo/CHEBI_71224 flavan-3,3',4',5,5',7-hexol A catechin that is a flavan substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7 (the trans isomaer). It is isolated from Acacia mearnsii. http://purl.obolibrary.org/obo/CHEBI_78121 fatty acid anion 14:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 14 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78128 fatty acid anion 24:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 24 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78129 fatty acid anion 26:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 26 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78130 fatty acid anion 28:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 28 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78131 fatty acid anion 30:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 30 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78138 fatty alcohol 18:0 http://purl.obolibrary.org/obo/CHEBI_24026 fatty alcohol Any fatty alcohol containing 18 carbons. http://purl.obolibrary.org/obo/CHEBI_90318 EC 6.4.1.1 (pyruvate carboxylase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76824 EC 6.4.1.* (carboxylase) inhibitor An EC 6.4.1.* (carboxylase) inhibitor that interferes with the action of pyruvate carboxylase (EC 6.4.1.1). http://purl.obolibrary.org/obo/CHEBI_32369 undecanoate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A medium-chain fatty acid anion that is the conjugate base of undecanoic acid; used in tandem with testosterone cation in the treatment of male hypogonadism. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_32402 catecholate(2-) http://purl.obolibrary.org/obo/CHEBI_50525 phenolate anion A phenolate anion that is the conjugate base of catecholate(1-). http://purl.obolibrary.org/obo/CHEBI_32457 cysteinate(2-) http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that has formula C3H5NO2S. http://purl.obolibrary.org/obo/CHEBI_32530 histidinate(2-) http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that has formula C6H7N3O2. http://purl.obolibrary.org/obo/CHEBI_32532 histidinium(2+) http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that has formula C6H11N3O2. http://purl.obolibrary.org/obo/CHEBI_32594 barium atom http://purl.obolibrary.org/obo/CHEBI_22313 alkaline earth metal atom An alkaline earth metal atom that has formula Ba. http://purl.obolibrary.org/obo/CHEBI_32697 argininium(2+) http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that has formula C6H16N4O2. http://purl.obolibrary.org/obo/CHEBI_32927 nonadecane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight-chain alkane with 19 carbon atoms. It has been found as a component of essential oils isolated from Artemisia armeniaca. http://purl.obolibrary.org/obo/CHEBI_32931 henicosane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane An alkane that has 21 carbons and a straight-chain structure. It has been isolated from plants like Periploca laevigata and Carthamus tinctorius. http://purl.obolibrary.org/obo/CHEBI_32936 tetracosane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight-chain alkane containing 24 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_33233 fundamental particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A particle not known to have substructure. http://purl.obolibrary.org/obo/CHEBI_33273 polyatomic anion http://purl.obolibrary.org/obo/CHEBI_36358 polyatomic ion An anion consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_33324 strontium atom http://purl.obolibrary.org/obo/CHEBI_22313 alkaline earth metal atom An alkaline earth metal atom that has formula Sr. http://purl.obolibrary.org/obo/CHEBI_33467 phosphorus(1+) http://purl.obolibrary.org/obo/CHEBI_33466 monoatomic phosphorus A monoatomic phosphorus that has formula P. http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_25367 molecule Any molecule that consists of a series of atoms joined together to form a ring. http://purl.obolibrary.org/obo/CHEBI_33597 homocyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclic compound having as ring members atoms of the same element only. http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A molecule that features two fused rings. http://purl.obolibrary.org/obo/CHEBI_33637 ortho-fused compound http://purl.obolibrary.org/obo/CHEBI_35293 fused compound A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms. http://purl.obolibrary.org/obo/CHEBI_33641 olefin http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes. http://purl.obolibrary.org/obo/CHEBI_33662 annulene http://purl.obolibrary.org/obo/CHEBI_33664 monocyclic hydrocarbon A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms. http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element. http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33497 transition element molecular entity A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element. http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity Hydrides are chemical compounds of hydrogen with other chemical elements. http://purl.obolibrary.org/obo/CHEBI_33847 monocyclic arene http://purl.obolibrary.org/obo/CHEBI_33658 arene A monocyclic aromatic hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_33848 polycyclic arene http://purl.obolibrary.org/obo/CHEBI_33666 polycyclic hydrocarbon A polycyclic aromatic hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_35104 strontium(2+) http://purl.obolibrary.org/obo/CHEBI_39129 strontium cation A strontium cation that has formula Sr. http://purl.obolibrary.org/obo/CHEBI_35986 nonan-1-ol http://purl.obolibrary.org/obo/CHEBI_24026 fatty alcohol A fatty alcohol consisting of a hydroxy function at C-1 of an unbranched saturated chain of nine carbon atoms. It has been isolated as a component of volatile oils from plants like Hordeum vulgare. http://purl.obolibrary.org/obo/CHEBI_35998 tridecane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight chain alkane containing 13 carbon atoms. It forms a component of the essential oils isolated from plants such as Abelmoschus esculentus. http://purl.obolibrary.org/obo/CHEBI_36339 baryon http://purl.obolibrary.org/obo/CHEBI_36344 hadron Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy). http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle http://purl.obolibrary.org/obo/BFO_0000040 material entity A particle smaller than an atom. http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A nucleus or any of its constituents in any of their energy states. http://purl.obolibrary.org/obo/CHEBI_36403 monocyclic olefin http://purl.obolibrary.org/obo/CHEBI_33642 cyclic olefin A monocyclic hydrocarbon having any number of double bonds. http://purl.obolibrary.org/obo/CHEBI_37136 barium(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation A barium cation that has formula 137.32700. http://purl.obolibrary.org/obo/CHEBI_64709 organic acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity that is acidic and contains carbon in covalent linkage. http://purl.obolibrary.org/obo/CHEBI_71449 hexadec-9-enoate http://purl.obolibrary.org/obo/CHEBI_78095 hexadecenoate A long-chain unsaturated fatty acid anion that is the conjugate base of hexadec-9-enoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_76042 aromatic amino-acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid. http://purl.obolibrary.org/obo/CHEBI_91007 aromatic carboxylate http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_48121 polyene http://purl.obolibrary.org/obo/CHEBI_33641 olefin An olefin that contains more than one carbon-carbon double bond. http://purl.obolibrary.org/obo/CHEBI_59999 chemical substance http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types. http://purl.obolibrary.org/obo/CHEBI_5171 friedelin http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is perhydropicene which is substituted by an oxo group at position 3 and by methyl groups at the 4, 4a, 6b, 8a, 11, 11, 12b, and 14a-positions (the 4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS-enantiomer). It is the major triterpenoid constituent of cork. http://purl.obolibrary.org/obo/CHEBI_51718 alpha,beta-unsaturated aldehyde http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde An aldehyde of general formula R(1)R(2)C=CR(3)-CH=O or RC#C-CH=O in which the aldehydic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_51721 alpha,beta-unsaturated ketone http://purl.obolibrary.org/obo/CHEBI_17087 ketone A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_51750 alpha,beta-unsaturated carboxylic acid amide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A monocarboxylic amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) or R(1)C#C-C(=O)NR(2)R(3) in which the amide C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. http://purl.obolibrary.org/obo/CHEBI_5203 Futoquinol http://purl.obolibrary.org/obo/CHEBI_25409 monoterpenoid A monoterpenoid that has formula C21H22O5. http://purl.obolibrary.org/obo/CHEBI_52629 EC 3.1.26.13 (retroviral ribonuclease H) inhibitor http://purl.obolibrary.org/obo/CHEBI_76785 EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor An inhibitor of ribonuclease H (EC 3.1.26.13), an enzyme required for specific hydrolysis of the RNA strand of an RNA/DNA hybrid. http://purl.obolibrary.org/obo/CHEBI_52845 cyclic organic group http://purl.obolibrary.org/obo/CHEBI_33247 organic group An organic group that consists of a closed ring. It may be a substituent or a skeleton. http://purl.obolibrary.org/obo/CHEBI_53309 polyanionic macromolecule http://purl.obolibrary.org/obo/CHEBI_53368 ionic macromolecule A polymer carrying multiple negative charges. http://purl.obolibrary.org/obo/CHEBI_53368 ionic macromolecule http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A macromolecule containing ionic groups. http://purl.obolibrary.org/obo/CHEBI_60090 7-hydroxyflavon-3-olate http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion Conjugate base of a 7-hydroxyflavonol compound arising from selective deprotonation of the 3-hydroxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_61910 very long-chain fatty acyl-CoA http://purl.obolibrary.org/obo/CHEBI_37554 fatty acyl-CoA A fatty acyl-CoA in which the fatty acyl group has a chain length greater than C22. http://purl.obolibrary.org/obo/CHEBI_76761 EC 3.2.* (glycosylase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor A hydrolase inhibitor that interferes with the action of any glycosylase (EC 3.2.*.*). http://purl.obolibrary.org/obo/CHEBI_76785 EC 3.1.26.* (endoribonucleases producing 5'-phosphomonoesters) inhibitor http://purl.obolibrary.org/obo/CHEBI_76760 EC 3.1.* (ester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any endoribonuclease producing 5'-phosphomonoesters (EC 3.1.26.*). http://purl.obolibrary.org/obo/CHEBI_66060 hypoglaunine B http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A sesquiterpene alkaloid that is a macrolide incorporating a substituted pyridine and dihydroagarofuran moieties. Isolated from root barks of Tripterygium hypoglaucum, it exhibits anti-HIV activity. http://purl.obolibrary.org/obo/CHEBI_66153 salaspermic acid http://purl.obolibrary.org/obo/CHEBI_70994 hexacyclic triterpenoid A hexacyclic triterpenoid that is D:A-friedooleanan-29-oic acid substituted by a hydroxy group at position 3 and an epoxy group across positions 3 and 24 (the (3beta,20alpha stereoisomer). Isolated from Salacia macrosperma and Tripterygium wilfordii, it exhibits anti-HIV activity. http://purl.obolibrary.org/obo/CHEBI_66275 tripterifordin http://purl.obolibrary.org/obo/CHEBI_38164 organic heteropentacyclic compound A kaurane diterpenoid that is (5beta,8alpha,13alpha)-18,20-epoxykauran-18-one substituted by a hydroxy group at position 16. Isolated from the roots of Tripterygium wilfordii, it exhibits anti-HIV activity. http://purl.obolibrary.org/obo/CHEBI_66276 triptonine A http://purl.obolibrary.org/obo/CHEBI_37668 terpene lactone A sesquiterpene alkaloid with anti-HIV activity isolated from Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_66277 triptonine B http://purl.obolibrary.org/obo/CHEBI_37668 terpene lactone A sesquiterpene alkaloid with anti-HIV activity isolated from Tripterygium hypoglaucum. http://purl.obolibrary.org/obo/CHEBI_6641 Magnoflorine http://purl.obolibrary.org/obo/CHEBI_24921 isoquinoline alkaloid An isoquinoline alkaloid that has formula C20H24NO4. http://purl.obolibrary.org/obo/CHEBI_66439 sciscllascilloside E-1 http://purl.obolibrary.org/obo/CHEBI_63566 pentasaccharide derivative A triterpenoid saponin isolated from Scilla scilloides and has been shown to exhibit anti-tumour activity. http://purl.obolibrary.org/obo/CHEBI_66470 (+)-sesamin http://purl.obolibrary.org/obo/CHEBI_38298 benzodioxoles A lignan that consists of tetrahydro-1H,3H-furo[3,4-c]furan substituted by 1,3-benzodioxole groups at positions 1 and 4 (the 1S,3aR,4S,6aR stereoisomer). Isolated from Cinnamomum camphora, it exhibits cytotoxic activity. http://purl.obolibrary.org/obo/CHEBI_66769 Polpunonic acid http://purl.obolibrary.org/obo/CHEBI_36615 triterpenoid A triterpenoid that has formula C30H48O3. http://purl.obolibrary.org/obo/CHEBI_67244 (-)-lariciresinol http://purl.obolibrary.org/obo/CHEBI_33853 phenols A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2R,3S,4S-diastereomer). http://purl.obolibrary.org/obo/CHEBI_67246 (+)-lariciresinol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A lignan that is tetrahydrofuran substituted at positions 2, 3 and 4 by 4-hydroxy-3-methoxyphenyl, hydroxymethyl and 4-hydroxy-3-methoxybenzyl groups respectively (the 2S,3R,4R-diastereomer). http://purl.obolibrary.org/obo/CHEBI_67554 daucosterol http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative A steroid saponin that is sitosterol attached to a beta-D-glucopyranosyl residue at position 3 via a glycosidic linkage. It has bee isolated from Panax japonicus var. major and Breynia fruticosa. http://purl.obolibrary.org/obo/CHEBI_90708 retinoic acid receptor modulator http://purl.obolibrary.org/obo/CHEBI_90709 nuclear receptor modulator A nuclear receptor modulator that affects the retinoic acid receptor http://purl.obolibrary.org/obo/CHEBI_92157 octadeca-9,12-dienoic acid http://purl.obolibrary.org/obo/CHEBI_18059 lipid A lipid that has formula C18H32O2. http://purl.obolibrary.org/obo/CHEBI_9380 syringin http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A monosaccharide derivative that is trans-sinapyl alcohol attached to a beta-D-glucopyranosyl residue at position 1 via a glycosidic linkage. http://purl.obolibrary.org/obo/CHEBI_9392 Talatizamine http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid that has formula C24H39NO5. http://purl.obolibrary.org/obo/UBERON_0000006 islet of Langerhans http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster the clusters of hormone-producing cells that are scattered throughout the pancreas http://purl.obolibrary.org/obo/UBERON_0000015 anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. http://purl.obolibrary.org/obo/UBERON_0000019 camera-type eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid. http://purl.obolibrary.org/obo/UBERON_0000025 tube http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. http://purl.obolibrary.org/obo/UBERON_0000026 appendage http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Major subdivision of an organism that protrudes from the body[DOS, CARO]. http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. http://purl.obolibrary.org/obo/UBERON_0000043 tendon http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue Dense regular connective tissue that connects muscle to bone[VSAO]. http://purl.obolibrary.org/obo/UBERON_0000047 simple eye http://purl.obolibrary.org/obo/UBERON_0000970 eye An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity. http://purl.obolibrary.org/obo/UBERON_0000055 vessel http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular structure that contains, conveys body fluid, such as blood or lymph. http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A tubular structure that transports secreted or excreted substances. http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. http://purl.obolibrary.org/obo/UBERON_0000062 organ http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that performs a specific function or group of functions [WP]. http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity. http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A multicellular structure that is a part of an organ. http://purl.obolibrary.org/obo/UBERON_0000066 fully formed stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. http://purl.obolibrary.org/obo/UBERON_0000067 embryo stage part http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage that is part of the embryo stage. http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A life cycle stage that starts with fertilization and ends with the fully formed embryo. http://purl.obolibrary.org/obo/UBERON_0000071 death stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage End of the life of an organism. http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. http://purl.obolibrary.org/obo/UBERON_0000076 external ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. http://purl.obolibrary.org/obo/UBERON_0000080 mesonephros http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The second stage of the kidney. It serves as the main excretory organ of aquatic vertebrates and as a temporary embryonic kidney in higher vertebrates. It is composed of the mesonephric duct (also called the Wolffian duct), mesonephric tubules, and associated capillary tufts. A single tubule and its associated capillary tuft is called a mesonephric excretory unit; these units are similar in structure and function to nephrons of the adult kidney. The mesonephros is derived from intermediate mesoderm in the vertebrate embryo. http://purl.obolibrary.org/obo/UBERON_0000081 metanephros http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine[GO] http://purl.obolibrary.org/obo/UBERON_0000083 mesonephric tubule http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube A mesonephric tubule is an epithelial tube that is part of the mesonephros[GO]. Genital ridge that is next to the mesonephros[WP]. http://purl.obolibrary.org/obo/UBERON_0000084 ureteric bud http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct An epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme[MP] http://purl.obolibrary.org/obo/UBERON_0000092 post-embryonic stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage stage succeeding embryo, including mature structure http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA] http://purl.obolibrary.org/obo/UBERON_0000104 life cycle http://purl.obolibrary.org/obo/BFO_0000015 process An entire span of an organism's life, commencing with the zygote stage and ending in the death of the organism. http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage http://purl.obolibrary.org/obo/BFO_0000015 process A spatiotemporal region encompassing some part of the life cycle of an organism. http://purl.obolibrary.org/obo/UBERON_0000106 zygote stage http://purl.obolibrary.org/obo/UBERON_0000067 embryo stage part A stage at which the organism is a single cell produced by means of sexual reproduction. http://purl.obolibrary.org/obo/UBERON_0000107 cleavage stage http://purl.obolibrary.org/obo/UBERON_0000067 embryo stage part The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. http://purl.obolibrary.org/obo/UBERON_0000108 blastula stage http://purl.obolibrary.org/obo/UBERON_0000067 embryo stage part An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000109 gastrula stage http://purl.obolibrary.org/obo/UBERON_0000067 embryo stage part A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/UBERON_0000110 neurula stage http://purl.obolibrary.org/obo/UBERON_0000067 embryo stage part Staged defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/UBERON_0000111 organogenesis stage http://purl.obolibrary.org/obo/UBERON_0000067 embryo stage part A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. http://purl.obolibrary.org/obo/UBERON_0000161 orifice http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0000162 cloaca http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures http://purl.obolibrary.org/obo/UBERON_0000163 embryonic cloaca http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]. http://purl.obolibrary.org/obo/UBERON_0000164 primitive urogenital sinus http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure the ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females http://purl.obolibrary.org/obo/UBERON_0000174 excreta http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is the product of an excretion process that will be eliminated from the body. An excretion process is elimination by an organism of the waste products that arise as a result of metabolic activity http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. http://purl.obolibrary.org/obo/UBERON_0000307 blastula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000320 duodenal mucosa http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine A mucosa that is part of a duodenum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000325 gastric gland http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. http://purl.obolibrary.org/obo/UBERON_0000328 gut wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity). http://purl.obolibrary.org/obo/UBERON_0000344 mucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP] http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma http://purl.obolibrary.org/obo/UBERON_0000064 organ part functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. http://purl.obolibrary.org/obo/UBERON_0000383 musculature of body http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. http://purl.obolibrary.org/obo/UBERON_0000409 serous gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland A gland in which the principal secretory cells are serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland A gland in which the principal secretory cells are mucus secreting cells. http://purl.obolibrary.org/obo/UBERON_0000456 bodily secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is produced by exocrine glands. http://purl.obolibrary.org/obo/UBERON_0000463 organism substance http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has mass. http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has no mass. http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that is an individual member of a species and consists of more than one cell. http://purl.obolibrary.org/obo/UBERON_0000471 compound organ component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Multi-tissue structure that is part of a compound organ. http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical group that has its parts adjacent to one another. http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA] http://purl.obolibrary.org/obo/UBERON_0000486 multilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA] http://purl.obolibrary.org/obo/UBERON_0000487 simple squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA] http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ Compound organ that contains one or more macroscopic anatomical spaces. http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA] http://purl.obolibrary.org/obo/UBERON_0000912 mucus http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Mucus is a bodily fluid consisting of a slippery secretion of the lining of the mucous membranes in the body. It is a viscous colloid containing antiseptic enzymes (such as lysozyme) and immunoglobulins. Mucus is produced by goblet cells in the mucous membranes that cover the surfaces of the membranes. It is made up of mucins and inorganic salts suspended in water. http://purl.obolibrary.org/obo/UBERON_0000916 abdomen http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0000922 embryo http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/UBERON_0000923 germ layer http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. http://purl.obolibrary.org/obo/UBERON_0000925 endoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. http://purl.obolibrary.org/obo/UBERON_0000926 mesoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer The middle germ layer of the embryo, between the endoderm and ectoderm. http://purl.obolibrary.org/obo/UBERON_0000930 stomodeum http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity. http://purl.obolibrary.org/obo/UBERON_0000931 proctodeum http://purl.obolibrary.org/obo/UBERON_0016566 pit Inward fold on the surface of the embryonic ectoderm that develops into an ectodermal terminal part of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint http://purl.obolibrary.org/obo/UBERON_0004905 articulation Anatomical cluster that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. http://purl.obolibrary.org/obo/UBERON_0000993 oviduct http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A tube or collection of tubes in an animal from the ovaries to the outside of the body. http://purl.obolibrary.org/obo/UBERON_0001009 circulatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Portion of connective tissue composed of adipocytes enmeshed in areolar tissue http://purl.obolibrary.org/obo/UBERON_0001015 musculature http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A subdivision of the muscular system corresponding to a subdisivision of an organism. http://purl.obolibrary.org/obo/UBERON_0001021 nerve http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. http://purl.obolibrary.org/obo/UBERON_0001033 gustatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The sensory system for the sense of taste. http://purl.obolibrary.org/obo/UBERON_0001041 foregut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Anterior subdivision of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0001045 midgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]. http://purl.obolibrary.org/obo/UBERON_0001046 hindgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The caudalmost subdivision of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. http://purl.obolibrary.org/obo/UBERON_0001049 neural tube http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/UBERON_0001064 ventral pancreatic duct http://purl.obolibrary.org/obo/UBERON_0007329 pancreatic duct A duct joining the pancreas to the common bile duct to supply pancreatic juices which aid in digestion provided by the exocrine pancreas. The pancreatic duct joins the common bile duct just prior to the ampulla of Vater, after which both ducts perforate the medial side of the second portion of the duodenum at the major duodenal papilla. http://purl.obolibrary.org/obo/UBERON_0001088 urine http://purl.obolibrary.org/obo/UBERON_0000174 excreta Excretion that is the output of a kidney http://purl.obolibrary.org/obo/UBERON_0001090 synovial fluid http://purl.obolibrary.org/obo/UBERON_0007794 serous fluid Transudate contained in the synovial cavity of joints, and in the cavity of tendon sheaths and bursae. http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Traditional gross anatomy divided the liver into four lobes based on surface features. The falciform ligament is visible on the front (anterior side) of the liver. This divides the liver into a left anatomical lobe, and a right anatomical lobe. http://purl.obolibrary.org/obo/UBERON_0001114 right lobe of liver http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver The right lobe is much larger than the left; the proportion between them being as six to one. It occupies the right hypochondrium, and is separated from the left lobe on its upper surface by the falciform ligament; on its under and posterior surfaces by the left sagittal fossa; and in front by the umbilical notch. It is of a somewhat quadrilateral form, its under and posterior surfaces being marked by three fossæ: the porta and the fossæ for the gall-bladder and inferior vena cava, which separate its left part into two smaller lobes; the quadrate and caudate lobes. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001115 left lobe of liver http://purl.obolibrary.org/obo/UBERON_0001113 lobe of liver The left lobe is smaller and more flattened than the right. It is situated in the epigastric and left hypochondriac regions. Its upper surface is slightly convex and is moulded on to the diaphragm; its under surface presents the gastric impression and omental tuberosity. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. http://en.wikipedia.org/wiki/ The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). http://purl.obolibrary.org/obo/UBERON_0001137 dorsum http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.. http://purl.obolibrary.org/obo/UBERON_0001152 cystic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct the tubular structure that conducts gall bladder contents from the gall bladder to the common bile duct http://purl.obolibrary.org/obo/UBERON_0001167 wall of stomach http://purl.obolibrary.org/obo/UBERON_0009034 stomach region the layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between http://purl.obolibrary.org/obo/UBERON_0001168 wall of small intestine http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine An anatomical wall that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001171 portal lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. http://purl.obolibrary.org/obo/UBERON_0001172 hepatic acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids. http://purl.obolibrary.org/obo/UBERON_0001175 common hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct Predominantly extrahepatic bile duct which is formed by the junction of the right and left hepatic ducts, which are predominantly intrahepatic, and, in turn, joins the cystic duct to form the common bile duct[GAID]. The common hepatic duct is the duct formed by the convergence of the right hepatic duct (which drains bile from the right functional lobe of the liver) and the left hepatic duct (which drains bile from the left functional lobe of the liver). The common hepatic duct then joins the cystic duct coming from the gallbladder to form the common bile duct[WP]. http://purl.obolibrary.org/obo/UBERON_0001176 right hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The duct that drains bile from the right half of the liver and joins the left hepatic duct to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0001177 left hepatic duct http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct The duct that drains bile from the left half of the liver and joins the right hepatic duct to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0001193 hepatic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the liver. http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach http://purl.obolibrary.org/obo/UBERON_0009034 stomach region The mucosal layer that lines the stomach. http://purl.obolibrary.org/obo/UBERON_0001202 pyloric sphincter http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter A strong ring of smooth muscle at the end of the pyloric canal which lets food pass from the stomach to the duodenum. It receives sympathetic innervation from the celiac ganglion[WP]. http://purl.obolibrary.org/obo/UBERON_0001204 mucosa of small intestine http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa A mucosa that is part of a small intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa The innermost membrane of the four coats of the intestinal wall, the other three being the submucosa, muscular layers, and serosa. (Berk et al., Gastroenterology, 4th ed, v.3, p1479) http://purl.obolibrary.org/obo/UBERON_0001246 interlobular bile duct http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad. http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001263 pancreatic acinus http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus The secretory units of the exocrine pancreas, where fluid containing digestive enzymes is produced; consists of a group of secretory cells surrounding a luminal space that connects to the pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0001271 pelvic girdle region http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium The epithelial layer of the stomach . http://purl.obolibrary.org/obo/UBERON_0001279 portal triad http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The functional units of the liver including the lobules. http://purl.obolibrary.org/obo/UBERON_0001282 intralobular bile duct http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct the tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule http://purl.obolibrary.org/obo/UBERON_0001353 anal region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anus and surrounding regions. Encompasses both internal and external regions, where present http://purl.obolibrary.org/obo/UBERON_0001434 skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. http://purl.obolibrary.org/obo/UBERON_0001443 chest http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk Subdivision of trunk proper, which is demarcated from the neck by the plane of the superior thoracic aperture and from the abdomen internally by the inferior surface of the diaphragm and externally by the costal margin and associated with the thoracic vertebral column and ribcage and from the back of the thorax by the external surface of the posterolateral part of the rib cage, the anterior surface of the thoracic vertebral column and the posterior axillary lines; together with the abdomen and the perineum, it constitutes the trunk proper[FMA]. http://purl.obolibrary.org/obo/UBERON_0001474 bone element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of bone tissue. http://purl.obolibrary.org/obo/UBERON_0001484 articular capsule http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001555 digestive tract http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/UBERON_0001556 lower urinary tract http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Subdivision of urinary system which consists of the urinary bladder and the urethra. http://purl.obolibrary.org/obo/UBERON_0001605 ciliary muscle http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. http://purl.obolibrary.org/obo/UBERON_0001690 ear http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. http://purl.obolibrary.org/obo/UBERON_0001772 corneal epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium the smooth stratified squamous epithelium that covers the outer surface of the cornea http://purl.obolibrary.org/obo/UBERON_0001773 sclera http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]. http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Any of the layers that make up the retina[MP]. http://purl.obolibrary.org/obo/UBERON_0001801 anterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive) http://purl.obolibrary.org/obo/UBERON_0001802 posterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive) http://purl.obolibrary.org/obo/UBERON_0001890 forebrain http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The most anterior region the brain including both the telencephalon and diencephalon. http://purl.obolibrary.org/obo/UBERON_0001891 midbrain http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. http://purl.obolibrary.org/obo/UBERON_0001895 metencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. http://purl.obolibrary.org/obo/UBERON_0001896 medulla oblongata http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]. http://purl.obolibrary.org/obo/UBERON_0001943 midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN10:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. http://purl.obolibrary.org/obo/UBERON_0001969 blood plasma http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid The liquid component of blood, in which erythrocytes are suspended. http://purl.obolibrary.org/obo/UBERON_0001970 bile http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium. http://purl.obolibrary.org/obo/UBERON_0001979 venule http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins http://purl.obolibrary.org/obo/UBERON_0001980 arteriole http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel The smallest division of the artery located between the muscular arteries and the capillaries[GO]. http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A vessel through which blood circulates in the body. http://purl.obolibrary.org/obo/UBERON_0001988 feces http://purl.obolibrary.org/obo/UBERON_0000174 excreta Portion of semisolid bodily waste discharged through the anus[MW,modified] http://purl.obolibrary.org/obo/UBERON_0002017 portal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]. http://purl.obolibrary.org/obo/UBERON_0002020 gray matter http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons. http://purl.obolibrary.org/obo/UBERON_0002028 hindbrain http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue that contains fibers that are divided by transverse bands into striations. http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anatomical structure that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0002072 hypodermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. http://purl.obolibrary.org/obo/UBERON_0002075 viscus http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen. http://purl.obolibrary.org/obo/UBERON_0002090 postcranial axial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The post-cranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. http://purl.obolibrary.org/obo/UBERON_0002091 appendicular skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]. http://purl.obolibrary.org/obo/UBERON_0002097 skin of body http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The organ covering the body that consists of the dermis and epidermis. http://purl.obolibrary.org/obo/UBERON_0002100 trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. http://purl.obolibrary.org/obo/UBERON_0002104 visual system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system subserving the sense of vision. http://purl.obolibrary.org/obo/UBERON_0002105 vestibulo-auditory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system Sensory system responsible for the perception of spatial orientation and auditory stimuli. http://purl.obolibrary.org/obo/UBERON_0002120 pronephros http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensible for larval life[GO]. http://purl.obolibrary.org/obo/UBERON_0002193 hemolymphoid system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. http://purl.obolibrary.org/obo/UBERON_0002199 integument http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The dermis, epidermis and hypodermis. http://purl.obolibrary.org/obo/UBERON_0002200 vasculature of head http://purl.obolibrary.org/obo/UBERON_0002049 vasculature Vasculature that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ Vasculature that is part of the eye region. http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA] http://purl.obolibrary.org/obo/UBERON_0002224 thoracic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the coelemic cavity lumen that is enclosed by the walls of the thorax. http://purl.obolibrary.org/obo/UBERON_0002294 biliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree). http://purl.obolibrary.org/obo/UBERON_0002323 coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities. http://purl.obolibrary.org/obo/UBERON_0002328 notochord http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. http://purl.obolibrary.org/obo/UBERON_0002329 somite http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0002342 neural crest http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. http://purl.obolibrary.org/obo/UBERON_0002346 neurectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Embryonic ectoderm that gives rise to nervous tissue. http://purl.obolibrary.org/obo/UBERON_0002355 pelvic region of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs. http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas http://purl.obolibrary.org/obo/UBERON_0002417 abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The abdominal segment of the torso. http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. http://purl.obolibrary.org/obo/UBERON_0002423 hepatobiliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The part of the digestive system that contains the liver and the biliary system http://purl.obolibrary.org/obo/UBERON_0002428 limb bone http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A bone that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002470 autopod region http://purl.obolibrary.org/obo/UBERON_0002529 limb segment Terminal segment of free limb, immediately distal to the zeugopod region. The fully developed autopod consists of the autopod skeleton plus associated structures such as integument, muscle tissue, vasculature etc. The autopod is divided into mesopodial, metapodiual, and acropodial segments. Examples: human hand, mouse paw, human foot http://purl.obolibrary.org/obo/UBERON_0002471 zeugopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment The middle free limb segment, between the autopod and stylopod segments. Includes as parts the zeugopodial skeleton. Examples: There are two types of zeugopod: forelimb zeugopod (aka forearm), hindlimb zeugopod (aka crus). http://purl.obolibrary.org/obo/UBERON_0002472 stylopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment The proximal free limb segment. Includes as parts the stylopod skeleton. http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. http://purl.obolibrary.org/obo/UBERON_0002513 endochondral bone http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element Replacement bone that forms within cartilage. http://purl.obolibrary.org/obo/UBERON_0002529 limb segment http://purl.obolibrary.org/obo/UBERON_0010538 paired limb/fin segment A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles. http://purl.obolibrary.org/obo/UBERON_0002530 gland http://purl.obolibrary.org/obo/UBERON_0000062 organ an organ that functions as a secretory or excretory organ http://purl.obolibrary.org/obo/UBERON_0002531 paired fin bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud An outgrowth on the lateral trunk of the embryo that develops into a paired fin. The fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA] http://purl.obolibrary.org/obo/UBERON_0002534 paired fin http://purl.obolibrary.org/obo/UBERON_0008897 fin Fin that is one of a pair located ventrally on the organism. http://purl.obolibrary.org/obo/UBERON_0002544 digit http://purl.obolibrary.org/obo/UBERON_0005881 autopodial extension A subdivision of the autopod that has as part a series of phalanges together with associated vasculature, musculature, integument and nerves. It is continuous with the metapodial subdivision of the autopod, but does not include the metapodials. In species such as humans, fully formed digits are distinct, whereas in other species the digits may be connected by interdigital webbing, or may be completely unseparated (for example, in cetaceans). http://purl.obolibrary.org/obo/UBERON_0002546 cranial placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. http://purl.obolibrary.org/obo/UBERON_0003052 midbrain-hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/UBERON_0003055 periderm http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A temporary epithelium that derives from the outer layer of the ectdoerm and is shed once the inner layer differentiates to form a true epidermis. http://purl.obolibrary.org/obo/UBERON_0003056 pre-chordal neural plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The portion of neural plate anterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003057 chordal neural plate http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The portion of neural plate posterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003059 presomitic mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. http://purl.obolibrary.org/obo/UBERON_0003060 pronephric duct http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium In mammals, the pronephric duct is the predecessor of the Wolffian duct[WP]. http://purl.obolibrary.org/obo/UBERON_0003061 blood island http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. http://purl.obolibrary.org/obo/UBERON_0003064 intermediate mesoderm http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/UBERON_0003068 axial mesoderm http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. http://purl.obolibrary.org/obo/UBERON_0003072 optic cup http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]. http://purl.obolibrary.org/obo/UBERON_0003073 lens placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]. http://purl.obolibrary.org/obo/UBERON_0003075 neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA] http://purl.obolibrary.org/obo/UBERON_0003077 paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO] http://purl.obolibrary.org/obo/UBERON_0003081 lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. http://purl.obolibrary.org/obo/UBERON_0003082 myotome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. http://purl.obolibrary.org/obo/UBERON_0003084 heart primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. http://purl.obolibrary.org/obo/UBERON_0003089 sclerotome http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. http://purl.obolibrary.org/obo/UBERON_0003100 female organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce female gametes. http://purl.obolibrary.org/obo/UBERON_0003101 male organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce male gametes. http://purl.obolibrary.org/obo/UBERON_0003102 surface structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. http://purl.obolibrary.org/obo/UBERON_0003103 compound organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage[XAO]. A mesh-like cell arrangement, less compact than an epithelium[ZFA]. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop[BTO]. http://purl.obolibrary.org/obo/UBERON_0003220 metanephric mesenchyme http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure one of the two embryological structures that give rise to the kidney (the other is the ureteric bud). The metanephric blastema mostly develops into nephrons, but can also form parts of the collecting duct system.[WP]. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros[GO] http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut http://purl.obolibrary.org/obo/UBERON_0003408 gland of gut A gland that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003314 eye mesenchyme http://purl.obolibrary.org/obo/UBERON_0010312 immature eye Mesenchyme that is part of a developing camera-type eye. http://purl.obolibrary.org/obo/UBERON_0003350 epithelium of mucosa http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A layer of epithelial cells on the surface of the mucosa. http://purl.obolibrary.org/obo/UBERON_0003386 smooth muscle of eye http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi http://purl.obolibrary.org/obo/UBERON_0003408 gland of gut http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A gland that is part of a digestive tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta. http://purl.obolibrary.org/obo/UBERON_0003606 limb long bone http://purl.obolibrary.org/obo/UBERON_0002428 limb bone A long bone that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003657 limb joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Any joint that is part of a (free) limb. http://purl.obolibrary.org/obo/UBERON_0003714 neural tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. http://purl.obolibrary.org/obo/UBERON_0003821 metapodium bone http://purl.obolibrary.org/obo/UBERON_0012357 digitopodium bone A bone of the metapodial skeleton http://purl.obolibrary.org/obo/UBERON_0003841 autopod joint http://purl.obolibrary.org/obo/UBERON_0003657 limb joint A limb joint that is part of an autopod [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003842 neural tube lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a neural tube. http://purl.obolibrary.org/obo/UBERON_0003849 mesencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a midbrain. http://purl.obolibrary.org/obo/UBERON_0003850 telencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a telencephalon. http://purl.obolibrary.org/obo/UBERON_0003852 rhombencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a hindbrain. http://purl.obolibrary.org/obo/UBERON_0003853 spinal cord neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a spinal cord. http://purl.obolibrary.org/obo/UBERON_0003886 future coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that has the potential to develop into a coelemic cavity lumen. http://purl.obolibrary.org/obo/UBERON_0003887 intraembryonic coelom http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom http://purl.obolibrary.org/obo/UBERON_0003894 liver primordium http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum. http://purl.obolibrary.org/obo/UBERON_0003902 retinal neural layer http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina The part of the retina that contains neurons and photoreceptor cells[GO]. http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/UBERON_0003918 kidney mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney[GO]. http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that carries blood from the capillaries toward the heart http://purl.obolibrary.org/obo/UBERON_0003921 pancreas primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure embryonic structure that develops into pancreatic bud. http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac The embryonic pancreas develops from two separate anlagen in the foregut epithelium, one dorsal and two ventral pancreatic buds[PMID]. http://purl.obolibrary.org/obo/UBERON_0003923 dorsal pancreatic bud http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud pancreatic bud that gives rise to the accessory pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0003924 ventral pancreatic bud http://purl.obolibrary.org/obo/UBERON_0003922 pancreatic epithelial bud pancreatic bud that gives rise to the major pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0003928 digestive system duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that lines the lumen of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0004016 dermatome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. http://purl.obolibrary.org/obo/UBERON_0004022 germinal neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells http://purl.obolibrary.org/obo/UBERON_0004058 biliary ductule http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure One of the fine terminal elements of the bile duct system, leaving the portal canal, and pursuing a course at the periphery of a lobule of the liver[BTO]. the excretory ducts of the liver that connect the interlobular ductules to the right or left hepatic duct[MP] http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer. http://purl.obolibrary.org/obo/UBERON_0004062 neural tube marginal layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter http://purl.obolibrary.org/obo/UBERON_0004088 orbital region http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any tube, opening or passage that connects two distinct anatomical spaces. http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the endoderm. http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the mesoderm. http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the ectoderm. http://purl.obolibrary.org/obo/UBERON_0004122 genitourinary system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction. http://purl.obolibrary.org/obo/UBERON_0004128 optic vesicle http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. http://purl.obolibrary.org/obo/UBERON_0004139 cardiogenic plate http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The first recognizable structure derived from the heart field http://purl.obolibrary.org/obo/UBERON_0004140 primary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. http://purl.obolibrary.org/obo/UBERON_0004141 heart tube http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A cardiac chamber surrounds an enclosed cavity within the heart http://purl.obolibrary.org/obo/UBERON_0004161 septum transversum http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]. http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The external genitalia are the outer sex organs, such as the penis or vulva in mammals http://purl.obolibrary.org/obo/UBERON_0004185 endodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portions of the gut that is derived from endoderm. http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A muscle that is part of the eye region. http://purl.obolibrary.org/obo/UBERON_0004288 skeleton http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. http://purl.obolibrary.org/obo/UBERON_0004290 dermomyotome http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure The bilaminar epithelium formed from the myotome and dermatome. http://purl.obolibrary.org/obo/UBERON_0004291 heart rudiment http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/UBERON_0004300 distal phalanx http://purl.obolibrary.org/obo/UBERON_0003221 phalanx Distal-most phalanx within a digit. http://purl.obolibrary.org/obo/UBERON_0004301 middle phalanx http://purl.obolibrary.org/obo/UBERON_0003221 phalanx A phalanx located between proximal and distal phalanges. http://purl.obolibrary.org/obo/UBERON_0004302 proximal phalanx http://purl.obolibrary.org/obo/UBERON_0003221 phalanx Proximal-most phalanx within a digit. http://purl.obolibrary.org/obo/UBERON_0004341 primitive streak http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The primitive streak is a structure that forms during the early stages of avian, reptilian and mammalian embryonic development[WP]. the midline ridge of the embryonic epiblast that later develops into mesoderm and endoderm[MP] http://purl.obolibrary.org/obo/UBERON_0004347 limb bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/UBERON_0004348 optic eminence http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic structure that gives rise to the corneal ectoderm http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/UBERON_0004370 anterior limiting lamina of cornea http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane. http://purl.obolibrary.org/obo/UBERON_0004375 bone of free limb or fin http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of an appendage [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004381 skeleton of limb http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton The collection of all skeletal elements in an individual limb. http://purl.obolibrary.org/obo/UBERON_0004456 entire sense organ system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Sum of all sensory systems in an organism. http://purl.obolibrary.org/obo/UBERON_0004529 anatomical projection http://purl.obolibrary.org/obo/UBERON_0034768 morphological feature A projection or outgrowth of tissue from a larger body or organ. http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vascular network consisting of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004572 arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all arteries. http://purl.obolibrary.org/obo/UBERON_0004582 venous system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions. http://purl.obolibrary.org/obo/UBERON_0004590 sphincter muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A structure, usually a circular muscle, that normally maintains constriction of a natural body passage or orifice and which relaxes as required by normal physiological functioning. http://purl.obolibrary.org/obo/UBERON_0004647 liver lobule http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure the polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin http://purl.obolibrary.org/obo/UBERON_0000026 appendage An appendage that is part of a appendage girdle complex. http://purl.obolibrary.org/obo/UBERON_0004716 conceptus http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres. http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An organ subunit that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004734 gastrula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the gastrula stage. http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. http://purl.obolibrary.org/obo/UBERON_0004770 articular system http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical system that consists of all the joints of the body. http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a gastrointestinal system. http://purl.obolibrary.org/obo/UBERON_0004808 gastrointestinal system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004819 kidney epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium the cellular avascular layer of the kidney luminar surfaces http://purl.obolibrary.org/obo/UBERON_0004872 splanchnic layer of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. http://purl.obolibrary.org/obo/UBERON_0004874 somatopleure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. http://purl.obolibrary.org/obo/UBERON_0004875 nephrogenic cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A portion of the urogenital ridge which is the source of much of the urinary system[WP]. http://purl.obolibrary.org/obo/UBERON_0004876 urogenital fold http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure One of of the pair of folds derived from the cloacal folds which give rise to a portion of the external genitalia; in male embryos they close over the urethral plate and fuse to form the spongy (penile) urethra and ventral aspect of the penis, not including the glans; failure of fusion of the urethral folds leads to hypospadias; in female embryos they fuse only anterior to the anus and form the labia minora[MP]. http://purl.obolibrary.org/obo/UBERON_0004880 chordamesoderm http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The central region of trunk mesoderm. This tissue forms the notochord http://purl.obolibrary.org/obo/UBERON_0004905 articulation http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that connects two or more adjacent skeletal elements or hardened body parts. http://purl.obolibrary.org/obo/UBERON_0004914 duodenal papilla http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ One of the two small elevations on the mucosa of the duodenum, the major at the entrance of the conjoined pancreatic and common bile ducts and the minor at the entrance of the accessory pancreatic duct. http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A proximal-distal subdivision of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of a wall of an organ that forms a layer. http://purl.obolibrary.org/obo/UBERON_0004998 mucosa of pylorus http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach A mucosa that is part of a pylorus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005061 neural groove http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds. http://purl.obolibrary.org/obo/UBERON_0005062 neural fold http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of the two elevated edges of the neural groove[GO,MP]. http://purl.obolibrary.org/obo/UBERON_0005068 neural rod http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]. http://purl.obolibrary.org/obo/UBERON_0005080 metanephric ureteric bud http://purl.obolibrary.org/obo/UBERON_0000084 ureteric bud The portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros[GO]. http://purl.obolibrary.org/obo/UBERON_0005081 ureter ureteric bud http://purl.obolibrary.org/obo/UBERON_0000084 ureteric bud The portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter[GO]. http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode http://purl.obolibrary.org/obo/UBERON_0001048 primordium An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO] http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. http://purl.obolibrary.org/obo/UBERON_0005095 kidney rudiment http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure . http://purl.obolibrary.org/obo/UBERON_0005103 mesonephric epithelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelium that is part of a mesonephros [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any anatomical structure that is part of the reproductive system. http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet bent on a linear axis. http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster A structure consisting of multiple cell components but which is not itself a cell and does not have (complete) cells as a part. http://purl.obolibrary.org/obo/UBERON_0005171 hepatic duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Any portion of the ducts that carry bile from the liver to the common bile duct. This may include both intrahapetic components (parts of left and right hepatic ducts) and extrahapetic components (common hepatic duct, plus hilar portion). http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back. http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. http://purl.obolibrary.org/obo/UBERON_0005179 pelvic region element http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element An organ or element that is part of the pelvic region. Examples: reproductive organs (in some organisms), urinary bladder, bones of the pelvis. http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a developing trunk. http://purl.obolibrary.org/obo/UBERON_0005290 myelencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A portion of tissue that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An array of photoreceptors and any supporting cells found in an eye. http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array. http://purl.obolibrary.org/obo/UBERON_0005425 presumptive neural retina http://purl.obolibrary.org/obo/UBERON_0010312 immature eye Portion of tissue that is the inner layer of the optic cup and will become the neural retina. http://purl.obolibrary.org/obo/UBERON_0005426 lens vesicle http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Portion of tissue that gives rise to the lens. http://purl.obolibrary.org/obo/UBERON_0005427 corneal primordium http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. http://purl.obolibrary.org/obo/UBERON_0005498 primitive heart tube http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that arises from the heart rudiment and will become the heart tube. http://purl.obolibrary.org/obo/UBERON_0005564 gonad primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Portion of tissue that gives rise to the immature gonad. http://purl.obolibrary.org/obo/UBERON_0005721 pronephric mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A mesoderm that has the potential to develop into a pronephros. http://purl.obolibrary.org/obo/UBERON_0005731 fin field http://purl.obolibrary.org/obo/UBERON_0005732 paired limb/fin field A limb/fin field that has_potential_to_developmentally_contribute_to a paired fin bud. http://purl.obolibrary.org/obo/UBERON_0005732 paired limb/fin field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A ring of cells capable of forming a limb or paired fin[Gilbert,modified]. http://purl.obolibrary.org/obo/UBERON_0005733 limb field http://purl.obolibrary.org/obo/UBERON_0005732 paired limb/fin field A ring of cells capable of forming a limb. http://purl.obolibrary.org/obo/UBERON_0005753 caudal part of nephrogenic cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The metanephros develops from the most caudal part of the nephrogenic cord that is itself derived from the intermediate plate mesoderm. http://purl.obolibrary.org/obo/UBERON_0005754 rostral part of nephrogenic cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The initial renal anlage that develops from the most rostral part of the nephrogenic cord is termed the pronephros. http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure A acellular anatomical structure that is the bounding layer of a anatomical structure. http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. http://purl.obolibrary.org/obo/UBERON_0005792 nephric ridge http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Nephric tubules (nephrons) form embryonically along the nephric ridge. The ridge comprises three regions; anterior, middle and posterior. The functional kidney uses nephrons from only one or two regions of the ridge. A pronephric kidney uses only the nephrons from the anterior region of the ridge. A mesonephric kidney uses only the middle region, a metanephric kidney uses only the posterior region and an opisthonephric kidney uses the middle and posterior regions. http://purl.obolibrary.org/obo/UBERON_0005806 portal system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]. http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation A delimited region of dense mesenchyme within looser mesenchyme. http://purl.obolibrary.org/obo/UBERON_0005863 cartilaginous condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. http://purl.obolibrary.org/obo/UBERON_0005881 autopodial extension http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A subdivision of the autopod that corresponds to one or more bones arranged in series branching from the main limb axis. http://purl.obolibrary.org/obo/UBERON_0005906 serous sac http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA] http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA] http://purl.obolibrary.org/obo/UBERON_0005944 axial skeleton plus cranial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa http://purl.obolibrary.org/obo/UBERON_0000064 organ part Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers. http://purl.obolibrary.org/obo/UBERON_0006215 rhombic lip http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure the posterior section of the developing metencephalon recognized transiently within the vertebrate embryo; the rhombic lip extends posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cell and can be divided into eight structural units based on rhombomeres 1-8 (r1-r8), recognized at early stages of hindbrain development; producing granule cells and five brainstem nuclei, the rhombic lip plays an important role in developing a complex cerebellar neural system http://purl.obolibrary.org/obo/UBERON_0006217 cloacal membrane http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The membrane that covers the embryonic cloaca, formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm; the urorectal septum joins the cloacal membrane and divides it into an anal membrane and a urogenital membrane; the point where the urorectal septum intersects the cloacal membrane is the future site of the perineal body; proliferation of mesoderm and ectoderm around the cloacal membrane produces primordial tissues of the external genitalia in both sexes: the genital tubercle, genital folds, and genital swellings. http://purl.obolibrary.org/obo/UBERON_0006235 foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junctions that overlaps the foregut and midgut. http://purl.obolibrary.org/obo/UBERON_0006238 future brain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic precursor of the brain. http://purl.obolibrary.org/obo/UBERON_0006240 future forebrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a forebrain. http://purl.obolibrary.org/obo/UBERON_0006242 gall bladder primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A sac-like cavity ventral to the liver, lying in the sub-mesodermal space and closed by a thin sheet of ectodermal cells, from which the future gall bladder develops. http://purl.obolibrary.org/obo/UBERON_0006267 notochordal plate http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. http://purl.obolibrary.org/obo/UBERON_0006268 notochordal process http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. http://purl.obolibrary.org/obo/UBERON_0006553 renal duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A tube in the kidney that collect and transport urine. http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube that is part of a excretory system. http://purl.obolibrary.org/obo/UBERON_0006595 presumptive endoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into endoderm. http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Portion of embryonic tissue determined by fate mapping to become a structure. http://purl.obolibrary.org/obo/UBERON_0006601 presumptive ectoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into ectoderm. http://purl.obolibrary.org/obo/UBERON_0006603 presumptive mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into mesoderm. http://purl.obolibrary.org/obo/UBERON_0006658 interphalangeal joint http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint A joint that connects one phalanx to another along a proximodistal axis. http://purl.obolibrary.org/obo/UBERON_0006716 mesopodium region http://purl.obolibrary.org/obo/UBERON_0002529 limb segment The third segment of the limb, including either the wrist segment (carpus) or the ankle segment (tarsus) http://purl.obolibrary.org/obo/UBERON_0006717 autopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision The collection of all skeletal elements in an autopodium region. http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is composed primarily of secretory cells. http://purl.obolibrary.org/obo/UBERON_0006866 terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a organ. http://purl.obolibrary.org/obo/UBERON_0006909 lumen of digestive tract http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a digestive tract. http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. http://purl.obolibrary.org/obo/UBERON_0006924 stomach glandular epithelium http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands. http://purl.obolibrary.org/obo/UBERON_0006925 digestive gland http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A gland, such as the liver or pancreas, that secretes into the alimentary canal substances necessary for digestion. http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA] http://purl.obolibrary.org/obo/UBERON_0006931 stomach glandular region mucosa http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region. http://purl.obolibrary.org/obo/UBERON_0006965 vascular cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n http://purl.obolibrary.org/obo/UBERON_0007005 cardiac mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. http://purl.obolibrary.org/obo/UBERON_0007010 cleaving embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the cleavage stage. http://purl.obolibrary.org/obo/UBERON_0007100 primary circulatory organ http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0007135 neural keel http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Mesenchyme that develops_from a cranial neural crest. http://purl.obolibrary.org/obo/UBERON_0007277 presumptive hindbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. http://purl.obolibrary.org/obo/UBERON_0007281 presumptive midbrain hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that gives rise to the midbrain hindbrain boundary. http://purl.obolibrary.org/obo/UBERON_0007282 presumptive segmental plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0007284 presumptive neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A presumptive structure that has the potential to develop into a neural plate. http://purl.obolibrary.org/obo/UBERON_0007285 presumptive paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a paraxial mesoderm. http://purl.obolibrary.org/obo/UBERON_0007297 presumptive pronephric mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a pronephric mesoderm. http://purl.obolibrary.org/obo/UBERON_0007324 pancreatic lobule http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A dense accumulation of exocrine glands in the pancreas often surrounding islets of Langerhans. http://purl.obolibrary.org/obo/UBERON_0007376 outer epithelium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. http://purl.obolibrary.org/obo/UBERON_0007377 stratum compactum http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer Portion of the dermis characterized by a well-arranged, plywood-like, collagenous network. http://purl.obolibrary.org/obo/UBERON_0007383 enveloping layer of ectoderm http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium Outermost layer of cells surrounding the embryo. http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac http://purl.obolibrary.org/obo/UBERON_0009856 sac An epithelial tube that is open at one end only. http://purl.obolibrary.org/obo/UBERON_0007500 epithelial tube open at both ends http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube An epithelial tube open at both ends that allows fluid flow. http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A closed epithelium with a lumen. http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme with little extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchymal cells that are migrating. http://purl.obolibrary.org/obo/UBERON_0007617 synovial cavity of joint http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical cavity that surrounded_by a synovial joint. http://purl.obolibrary.org/obo/UBERON_0007625 pigment epithelium of eye http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules. http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that connects two structures http://purl.obolibrary.org/obo/UBERON_0007687 kidney field http://purl.obolibrary.org/obo/UBERON_0007688 anlage region of the embryo into the area in which the kidney rudiment will develop. http://purl.obolibrary.org/obo/UBERON_0007688 anlage http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. http://purl.obolibrary.org/obo/UBERON_0007794 serous fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Any fluid produced by a serous gland. http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. http://purl.obolibrary.org/obo/UBERON_0007823 appendage girdle region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0007832 pelvic girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton Skeletal subdivision consisting of a set of bones linking the axial series to the hindlimb zeugopodium and offering anchoring areas for hindlimb and caudal musculature. http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of cartilage tissue and may be permanent or transient. http://purl.obolibrary.org/obo/UBERON_0007845 regular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue. http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts). http://purl.obolibrary.org/obo/UBERON_0008835 hepatic diverticulum http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. http://purl.obolibrary.org/obo/UBERON_0008858 pyloric canal http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach The short narrow part of the stomach extending from the pyloric antrum to the pyloric sphincter http://purl.obolibrary.org/obo/UBERON_0008861 pyloric gastric gland http://purl.obolibrary.org/obo/UBERON_0000414 mucous gland The gastric glands in the pyloric region of the stomach; the pyloric glands secrete mucin, which coats the stomach and protects it, and hormones such as gastrin and enkephalin[MP]. http://purl.obolibrary.org/obo/UBERON_0008897 fin http://purl.obolibrary.org/obo/UBERON_0000026 appendage An external projection of an aquatic animal as a fish used in propelling or guiding the body[BTO]. http://purl.obolibrary.org/obo/UBERON_0009034 stomach region http://purl.obolibrary.org/obo/UBERON_0000064 organ part An organ part that is part of a stomach. http://purl.obolibrary.org/obo/UBERON_0009117 indifferent gonad http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A gonad prior to differentiating into a definitive testis or ovary. http://purl.obolibrary.org/obo/UBERON_0009142 entire embryonic mesenchyme http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Sum total of mesenchyme in the embryo. http://purl.obolibrary.org/obo/UBERON_0009201 nephric duct http://purl.obolibrary.org/obo/UBERON_0006555 excretory tube A nephric duct is a tube that drains a primitive kidney[GO]. http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0009550 endoderm of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0009551 distal segment of digit http://purl.obolibrary.org/obo/UBERON_0002529 limb segment A segment of a digit containing the distal phalanx, and overlapping the distal interphalangeal joint[CJM]. The digit tip is derived from multiple and distinct embryonic origins, and includes the distal bone with associated marrow cavity and haematopoietic cells, ventral (flexor) and dorsal (extensor) tendons, sweat glands with myoepithelial and luminal secreting cells and associated neurons for innervation, dermis with resident melanocytes and dendritic cells, mesenchyme with resident fibroblasts, skin epidermis with hair follicles, a nail organ composed of six specific parts (the root, nail bed, nail plate, eponychium (cuticle), perionychium and hyponychium). http://purl.obolibrary.org/obo/UBERON_0009564 distal limb integumentary appendage http://purl.obolibrary.org/obo/UBERON_0013703 integumentary projection A nail, hoof or claw. http://purl.obolibrary.org/obo/UBERON_0009616 presumptive midbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a midbrain. http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells. http://purl.obolibrary.org/obo/UBERON_0009768 distal interphalangeal joint http://purl.obolibrary.org/obo/UBERON_0006658 interphalangeal joint An inter-phalangeal joint that connects a distal phalanx to either a medial or proximal phalanx. http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form. http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0009856 sac Branch or outpocketing of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland. http://purl.obolibrary.org/obo/UBERON_0009877 metapodium region http://purl.obolibrary.org/obo/UBERON_0002529 limb segment Intermediate segment of the autopod, between the mesopodial region and and acropodial region. Examples: metacarpal region, metatarsal region http://purl.obolibrary.org/obo/UBERON_0009878 mesopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision The collection of all skeletal elements in a mesopodium. Examples: the tarsal skeleton, the carpal skeleton http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a developing face. http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has more than one cell as a part. http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element An organ of the digestive tract that is capable of retaining and storing food http://purl.obolibrary.org/obo/UBERON_0010081 future common hepatic duct http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system An extrahepatic bile duct that has the potential to develop into a common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0010083 future dermis http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Mesenchyme that has the potential to develop into a dermis. http://purl.obolibrary.org/obo/UBERON_0010092 future metencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a metencephalon. http://purl.obolibrary.org/obo/UBERON_0010096 future myelencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a myelencephalon. http://purl.obolibrary.org/obo/UBERON_0010130 autopod plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The distal elements of the developing limb of vertebrates that will give rise to the pedal appendages (e.g. manus, pes, paw) http://purl.obolibrary.org/obo/UBERON_0010230 eyeball of camera-type eye http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The core globe-shaped component of the camera-type eye. http://purl.obolibrary.org/obo/UBERON_0010285 midbrain basal plate http://purl.obolibrary.org/obo/UBERON_0002020 gray matter Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. http://purl.obolibrary.org/obo/UBERON_0010286 midbrain neural tube http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of neural tube that gives rise to the midbrain. http://purl.obolibrary.org/obo/UBERON_0010312 immature eye http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Developing anatomical structure that develops into the eyeball and associated structures. http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An anatomical structure that develops from the neural crest. http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has some part that develops from the neural crest. http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification. http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Epithelium composed of cells that develops from the ectoderm[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a somatopleure. http://purl.obolibrary.org/obo/UBERON_0010409 ocular surface region http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms. http://purl.obolibrary.org/obo/UBERON_0010427 ciliary processes http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens. http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. http://purl.obolibrary.org/obo/UBERON_0010538 paired limb/fin segment http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis An appendage segment that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0010543 acropodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision The subdivision of the skeleton that consists of all the skeletal elements at the distalmost end of the autopodium - i.e. the bones of the digits or their cartilaginous precursors[VSAO,modified]. http://purl.obolibrary.org/obo/UBERON_0010546 metapodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision Subdivision of skeleton that corresponds to metapodium region, between acropodial skeleton and mesopdoial skeleton. http://purl.obolibrary.org/obo/UBERON_0010702 digit mesenchyme http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme Mesenchyme of the digit region. http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes both an appendage and its accociated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0010709 pelvic complex http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that is a segment of the limb skeleton. http://purl.obolibrary.org/obo/UBERON_0010713 paired fin skeleton http://purl.obolibrary.org/obo/UBERON_0012353 fin skeleton The collection of all skeletal elements in a single paired fin. http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The subdivision of the skeleton of either the pectoral or pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle). http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along an axis perpedicular to the main body anterior-posterior axis. In vertebrates, this is typically a fin or limb segment. In insects, this includes segments of appendages such as antennae, as well as segments of the insect leg. http://purl.obolibrary.org/obo/UBERON_0010881 limb cartilage element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A skeletal element that is part of a limb and composed of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0010882 limb bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A skeletal element that is part of a limb and composed of pre-cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. http://purl.obolibrary.org/obo/UBERON_0011137 axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011138 post-cranial axial skeletal system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Subdivision of the skeletal system which consists of the post-cranial axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011139 synovial limb joint http://purl.obolibrary.org/obo/UBERON_0003657 limb joint Any synovial joint that is part of a (free) limb. http://purl.obolibrary.org/obo/UBERON_0011143 upper urinary tract http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Subdivision of urinary system which consists of the kidney and the ureters. http://purl.obolibrary.org/obo/UBERON_0011185 gastrointestinal sphincter http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A sphincter muscle that is part of the gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A multi cell part structure that is part of a central nervous system. http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A subdivision of an anatomical system. http://purl.obolibrary.org/obo/UBERON_0011249 appendicular skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011250 autopod bone http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A bone that is part of a autopod region. Note that this incudes the carpal and tarsal bones. http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in an individual limb or fin. http://purl.obolibrary.org/obo/UBERON_0011583 stylopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision Proximal element of a free limb skeleton consisting of the femur and humerus in the forelimb stylopodium and hindlimb stylopodium respectively[VSAO, modified]. http://purl.obolibrary.org/obo/UBERON_0011584 zeugopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision Section of the forelimb skeleton located between the stylopodium and the autopodium. http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011695 embryonic cardiovascular system http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system A cardiovascular system that is part of a conceptus. http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that does not develop into a component of the nervous system. http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus An acinus that is part of a exocrine gland. http://purl.obolibrary.org/obo/UBERON_0011892 anterior uvea http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris. http://purl.obolibrary.org/obo/UBERON_0011899 epimysium http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. http://purl.obolibrary.org/obo/UBERON_0011953 stomach glandular region http://purl.obolibrary.org/obo/UBERON_0009034 stomach region A region of the stomach that is lined with glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0011997 coelom http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The aggregate of the coelemic cavity lumen plus the membranes that line the lumen. http://purl.obolibrary.org/obo/UBERON_0012140 digitopodium region http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod A segment of the autopod consisting of both acropodial region and metapodial region, but excluding the mesopodial/basopodial region. http://purl.obolibrary.org/obo/UBERON_0012150 skeleton of digitopodium http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision A subdivision of the autopod skeleton consisting of both acropodial skeleon and metapodial skeleton, but excluding the mesopodial/basopodial skeleton. http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified] http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Epithelium that derives from the mesoderm. [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012292 embryonic cloacal fold http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure One of the pair of mesenchymal swellings (folds) located on either side of the cloacal membrane during the indifferent stage of embryonic development; cranial to the cloacal membrane the folds unite to form the genital tubercle; caudally the folds are subdivided into urogenital folds anteriorly and anal folds posteriorly http://purl.obolibrary.org/obo/UBERON_0012353 fin skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision consisting of all the skeletal elements in a single fin. http://purl.obolibrary.org/obo/UBERON_0012354 acropodium region http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod The segment of the autopod that is distal to the metapodial region and consists of the digits. http://purl.obolibrary.org/obo/UBERON_0012357 digitopodium bone http://purl.obolibrary.org/obo/UBERON_0011250 autopod bone A bone that is part of a the digitopodium skeleton - i.e. the acropodial skeleton or the metapodial skeleton. http://purl.obolibrary.org/obo/UBERON_0012429 hemopoietic tissue http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue Blood-forming tissue, consisting of reticular fibers and cells. Also known as hemopoietic tissue http://purl.obolibrary.org/obo/UBERON_0012430 tunica fibrosa of eyeball http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth. http://purl.obolibrary.org/obo/UBERON_0012476 skeleton of pelvic complex http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in a pelvic complex - i.e. the combination of free limb or fin plus pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0013241 embryonic urethral groove http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The precursor of the urethra http://purl.obolibrary.org/obo/UBERON_0013514 space surrounding organism http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The space that surrounds an organism. http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A section through the tube or network of tubes that connects the ovaries to the outside of the body. http://purl.obolibrary.org/obo/UBERON_0013686 anatomical conduit space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0013701 main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. http://purl.obolibrary.org/obo/UBERON_0013702 body proper http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The region of the organism associated with the visceral organs. http://purl.obolibrary.org/obo/UBERON_0013703 integumentary projection http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa Anatomical projection that is part of the integumentl system. http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A organ component layer that is part of a integumental system. http://purl.obolibrary.org/obo/UBERON_0013756 venous blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element http://purl.obolibrary.org/obo/UBERON_0000062 organ Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. http://purl.obolibrary.org/obo/UBERON_0014371 future telencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that gives rise to the telencephalon. http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Mesenchyme that develops_from the neural crest[Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0014477 thoracic skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory. http://purl.obolibrary.org/obo/UBERON_0014719 intralobular duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is located within a lobule, with no more connective tissue intervening between ducts and secretory units (i.e., acini or tubules) than between adjacent secretory units. Intercalated and striated ducts are intralobular http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). http://purl.obolibrary.org/obo/UBERON_0014903 primordial vasculature http://purl.obolibrary.org/obo/UBERON_0001048 primordium A portion of tissue that will develop into vasculature. http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A phalanx bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A limb bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A endochondral element that is part of a autopod region. http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage http://purl.obolibrary.org/obo/UBERON_0015063 autopod endochondral element A autopod endochondral element that is composed primarily of a cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any structure that is placed on one side of the left-right axis of a bilaterian. http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A epithelium that is part of a camera-type eye. http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium A epithelium that is part of a foregut. http://purl.obolibrary.org/obo/UBERON_0016566 pit http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface An roughly circular indentation in a surface. http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the central nervous system http://purl.obolibrary.org/obo/UBERON_0016880 future nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the nervous system http://purl.obolibrary.org/obo/UBERON_0016887 entire extraembryonic component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element A viscus that is part of a abdomen. http://purl.obolibrary.org/obo/UBERON_0019207 chorioretinal region http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The part of the eye that consists of both the retina and the optic choroid http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]. http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An embryonic or larval epithelium that is committed to form part of the nervous system. http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. http://purl.obolibrary.org/obo/UBERON_0034768 morphological feature http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A part of an organism or organ that is continuous with its surroundings and distinguished from its surroundings based on morphology. http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure An multicellular anatomical structure that has subparts of multiple organs as a part. http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A cluster of cells, largely surrounded by a morphological boundary. http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity A collection of anatomical structures that are alike in terms of their morphology or developmental origin. http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. http://purl.obolibrary.org/obo/UBERON_0034932 epithelium of biliary system http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The epithelial layer covering the biliary system. This includes the epithelium of the gallbladder (when present) as well as the intrahepatic and extrahepatic bile ducts. http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure http://purl.obolibrary.org/obo/UBERON_0003102 surface structure Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. http://purl.obolibrary.org/obo/UBERON_5002544 digit plus metapodial segment http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A subdivision of the autopod consisting of digit plus the region incorporating a single metapodial element. These segments are typically repeated along the pre-axiom to post-axial axis. http://purl.obolibrary.org/obo/UBERON_5102544 individual digit of digitopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision A subdivision of the skeleton of the autopod consisting of the phalanges of a single digit plus the associated metapodial element. http://purl.obolibrary.org/obo/DRON_00000005 drug product http://purl.obolibrary.org/obo/BFO_0000040 material entity a material entity (1) containing at least one scattered molecular aggregate as part that is the bearer of an active ingredient role and (2) that is itself the bearer of a clinical drug role http://purl.obolibrary.org/obo/DRON_00000028 active ingredient http://purl.obolibrary.org/obo/DRON_00000030 role of scattered molecular aggregate a role of a scattered molecular aggregate that is part of a drug product that is realized by (1) administration of the drug to an organism followed by (2) some change in the structure or functioning of some part of the organism http://purl.obolibrary.org/obo/DRON_00000030 role of scattered molecular aggregate http://purl.obolibrary.org/obo/BFO_0000023 role a role borne by a scattered molecular aggregate and realized by its grains participating in one or more processes http://purl.obolibrary.org/obo/DRON_00000031 drug administration http://purl.obolibrary.org/obo/OGMS_0000090 treatment a treatment that has as participants an extended organism and a drug product and that results in part of the drug product being located in the extended organism http://purl.obolibrary.org/obo/OGMS_0000061 pathological bodily process http://purl.obolibrary.org/obo/OGMS_0000060 bodily process A bodily process that is clinically abnormal. http://purl.obolibrary.org/obo/CHEBI_10545 electron http://purl.obolibrary.org/obo/CHEBI_36338 lepton Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV. http://purl.obolibrary.org/obo/CHEBI_15346 coenzyme A http://purl.obolibrary.org/obo/CHEBI_37240 adenosine 3',5'-bisphosphate A thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit. http://purl.obolibrary.org/obo/CHEBI_15385 (+)-delta-cadinene http://purl.obolibrary.org/obo/CHEBI_22976 cadinene A member of the cadinene family of sesquiterpenes in which the double bonds are located at the 4-4a and 7-8 positions, and in which the isopropyl group at position 1 is cis to the hydrogen at the adjacent bridgehead carbon (the 1S,8aR-enantiomer). http://purl.obolibrary.org/obo/CHEBI_15428 glycine http://purl.obolibrary.org/obo/CHEBI_26650 serine family amino acid The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. http://purl.obolibrary.org/obo/CHEBI_15440 squalene http://purl.obolibrary.org/obo/CHEBI_35191 triterpene A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration. http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. http://purl.obolibrary.org/obo/CHEBI_17268 myo-inositol http://purl.obolibrary.org/obo/CHEBI_24848 inositol An inositol having myo- configuration. http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group. http://purl.obolibrary.org/obo/CHEBI_17987 benzyl alcohol http://purl.obolibrary.org/obo/CHEBI_22743 benzyl alcohols An aromatic alcohol that consists of benzene bearing a single hydroxymethyl substituent. http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_63161 glycosyl compound A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively. http://purl.obolibrary.org/obo/CHEBI_24436 guanidines http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas. http://purl.obolibrary.org/obo/CHEBI_24848 inositol http://purl.obolibrary.org/obo/CHEBI_23451 cyclitol Any cyclohexane-1,2,3,4,5,6-hexol. http://purl.obolibrary.org/obo/CHEBI_25754 oxo carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any compound that has an aldehydic or ketonic group as well as a carboxylic acid group in the same molecule. http://purl.obolibrary.org/obo/CHEBI_27417 p-xylene http://purl.obolibrary.org/obo/CHEBI_27338 xylene A xylene with methyl groups at positions 1 and 4. http://purl.obolibrary.org/obo/CHEBI_28063 o-xylene http://purl.obolibrary.org/obo/CHEBI_27338 xylene A xylene substituted by methyl groups at positions 1 and 3. http://purl.obolibrary.org/obo/CHEBI_28863 flavanones http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone Members of the class of flavans with a 3,4-dihydro-2-aryl-2H-1-benzopyran-4-one skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_28903 decan-1-ol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A fatty alcohol consisting of a hydroxy function at C-1 of an unbranched saturated chain of ten carbon atoms. http://purl.obolibrary.org/obo/CHEBI_29019 nonanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C9 straight-chain saturated fatty acid which occurs naturally as esters of the oil of pelargonium. Has antifungal properties, and is also used as a herbicide as well as in the preparation of plasticisers and lacquers. http://purl.obolibrary.org/obo/CHEBI_32368 undecanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain, eleven-carbon saturated medium-chain fatty acid found in body fluids; the most fungitoxic of the C7:0 - C18:0 fatty acid series. http://purl.obolibrary.org/obo/CHEBI_33286 agrochemical http://purl.obolibrary.org/obo/CHEBI_33232 application An agrochemical is a substance that is used in agriculture or horticulture. http://purl.obolibrary.org/obo/CHEBI_33642 cyclic olefin http://purl.obolibrary.org/obo/CHEBI_33641 olefin The inclusive term for any cyclic hydrocarbon having any number of double bonds. http://purl.obolibrary.org/obo/CHEBI_36338 lepton http://purl.obolibrary.org/obo/CHEBI_36340 fermion Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin). http://purl.obolibrary.org/obo/CHEBI_37912 hydroxycoumarin http://purl.obolibrary.org/obo/CHEBI_23403 coumarins Any coumarin carrying at least one hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines A pyrimidine carrying one or more oxo substituents. http://purl.obolibrary.org/obo/CHEBI_38757 isoflavones http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone Any isoflavonoid with a 3-aryl-1-benzopyran-4-one (3-aryl-4H-chromen-4-one) skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_38975 methylbenzene http://purl.obolibrary.org/obo/CHEBI_38976 alkylbenzene Any alkylbenzene that is benzene substituted with one or more methyl groups. http://purl.obolibrary.org/obo/CHEBI_46342 undecane http://purl.obolibrary.org/obo/CHEBI_18310 alkane A straight-chain alkane with 11 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_50401 cholestanoid http://purl.obolibrary.org/obo/CHEBI_35341 steroid Any steroid based on a cholestane skeleton and its derivatives. http://purl.obolibrary.org/obo/CHEBI_51277 thioester http://purl.obolibrary.org/obo/CHEBI_26959 thiocarboxylic ester A compound of general formula RC(=O)SR'. Compare with thionoester, RC(=S)OR'. http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). http://purl.obolibrary.org/obo/CHEBI_15489 3-oxo-fatty acyl-CoA http://purl.obolibrary.org/obo/CHEBI_61903 oxo-fatty acyl-CoA An oxo fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any 3-oxo-fatty acid.. http://purl.obolibrary.org/obo/CHEBI_16243 quercetin http://purl.obolibrary.org/obo/CHEBI_52267 7-hydroxyflavonol A pentahydroxyflavone having the five hydroxy groups placed at the 3-, 3'-, 4'-, 5- and 7-positions. http://purl.obolibrary.org/obo/CHEBI_16433 trans-caffeic acid http://purl.obolibrary.org/obo/CHEBI_36281 caffeic acid The trans-isomer of caffeic acid. http://purl.obolibrary.org/obo/CHEBI_17272 propionate http://purl.obolibrary.org/obo/CHEBI_78113 fatty acid anion 3:0 The conjugate base of propionic acid; a key precursor in lipid biosynthesis. http://purl.obolibrary.org/obo/CHEBI_17580 linalool http://purl.obolibrary.org/obo/CHEBI_26878 tertiary alcohol A monoterpenoid that is octa-1,6-diene substituted by methyl groups at positions 3 and 7 and a hydroxy group at position 3. It has been isolated from plants like Ocimum canum. http://purl.obolibrary.org/obo/CHEBI_22860 amino-acid betaine http://purl.obolibrary.org/obo/CHEBI_35284 ammonium betaine Any amino acid-derived zwitterion - such as glycine betaine (N,N,N-trimethylammonioacetate) - in which the ammonium nitrogen carries three methyl substituents. http://purl.obolibrary.org/obo/CHEBI_28866 tetracosanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C24 straight-chain saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_31009 hexacosanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A 26-carbon, straight-chain, saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_36132 alicyclic ketone http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone A cyclic ketone in which the carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system. http://purl.obolibrary.org/obo/CHEBI_36241 3,4-dihydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_36084 dihydroxybenzoate A dihydroxybenzoate having the two hydroxy groups located at the 3- and 4-positions. http://purl.obolibrary.org/obo/CHEBI_37488 trihydroxyanthraquinone http://purl.obolibrary.org/obo/CHEBI_37485 hydroxyanthraquinones A member of the class of hydroxyanthraquinones carrying three hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_42394 tricosanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A very long-chain fatty acid that is tricosane in which one of the methyl groups has been oxidised to the corresponding carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_58955 branched-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion with a carbon side-chain or isopropyl termination. http://purl.obolibrary.org/obo/CHEBI_131869 hydroxy monounsaturated fatty acid http://purl.obolibrary.org/obo/CHEBI_25413 monounsaturated fatty acid Any monounsaturated fatty acid carrying one or more hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_16113 cholesterol http://purl.obolibrary.org/obo/CHEBI_35348 3beta-sterol A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group. http://purl.obolibrary.org/obo/CHEBI_16398 D-threonine http://purl.obolibrary.org/obo/CHEBI_26986 threonine An optically active form of threonine having D-configuration. http://purl.obolibrary.org/obo/CHEBI_17608 D-aldohexose http://purl.obolibrary.org/obo/CHEBI_4194 D-hexose Any D-aldose having a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/CHEBI_17634 D-glucose http://purl.obolibrary.org/obo/CHEBI_17608 D-aldohexose A glucose with D-configuration. http://purl.obolibrary.org/obo/CHEBI_18254 ribonucleoside http://purl.obolibrary.org/obo/CHEBI_47019 dihydroxytetrahydrofuran Any nucleoside where the sugar component is D-ribose. http://purl.obolibrary.org/obo/CHEBI_26208 polyunsaturated fatty acid http://purl.obolibrary.org/obo/CHEBI_27208 unsaturated fatty acid Any fatty acid containing more than one double bond. Acids in this group are reported to have cardioprotective effects; and levels are lowered in chronic fatigue syndrome. http://purl.obolibrary.org/obo/CHEBI_28260 galactose http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose An aldohexose that is the C-4 epimer of glucose. http://purl.obolibrary.org/obo/CHEBI_29990 D-aspartate(1-) http://purl.obolibrary.org/obo/CHEBI_35391 aspartate(1-) An aspartate(1-) that is the conjugate base of D-aspartic acid. http://purl.obolibrary.org/obo/CHEBI_29991 L-aspartate(1-) http://purl.obolibrary.org/obo/CHEBI_62031 polar amino acid zwitterion An aspartate(1-) that is the conjugate base of L-aspartic acid. http://purl.obolibrary.org/obo/CHEBI_48706 antagonist http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. http://purl.obolibrary.org/obo/CHEBI_48741 beta-phellandrene http://purl.obolibrary.org/obo/CHEBI_50034 phellandrene One of a pair of phellandrene cyclic monoterpene double-bond isomers in which one double bond is exocyclic (cf. alpha-phellandrene, where both of them are endoocyclic). http://purl.obolibrary.org/obo/CHEBI_51921 heptadienal http://purl.obolibrary.org/obo/CHEBI_51688 enal An seven carbon-enal containing one extra C=C double bond, which may or may not be conjugated with the aldehydic C=O and alpha,beta-double bond systems. http://purl.obolibrary.org/obo/CHEBI_26833 sulfur atom http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen A chalcogen that has formula S. http://purl.obolibrary.org/obo/CHEBI_26959 thiocarboxylic ester http://purl.obolibrary.org/obo/CHEBI_35701 ester An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur. http://purl.obolibrary.org/obo/CHEBI_27081 transition element atom http://purl.obolibrary.org/obo/CHEBI_33521 metal atom An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell. http://purl.obolibrary.org/obo/CHEBI_27363 zinc atom http://purl.obolibrary.org/obo/CHEBI_33340 zinc group element atom A zinc group element atom that has formula Zn. http://purl.obolibrary.org/obo/CHEBI_28409 triacontan-1-ol http://purl.obolibrary.org/obo/CHEBI_78145 fatty alcohol 30:0 A fatty alcohol 30:0 that has formula C30H62O. http://purl.obolibrary.org/obo/CHEBI_28838 lutein http://purl.obolibrary.org/obo/CHEBI_23045 carotenol A carotenol that has formula C40H56O2. http://purl.obolibrary.org/obo/CHEBI_32504 phenylalaninate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An aromatic amino-acid anion that is the conjugate base of phenylalanine, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32505 phenylalaninium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that is the conjugate acid of phenylalanine, arising from protonation of the amino group. http://purl.obolibrary.org/obo/CHEBI_32529 histidinate(1-) http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An alpha-amino-acid anion that has formula C6H8N3O2. http://purl.obolibrary.org/obo/CHEBI_32531 histidinium(1+) http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that has formula C6H10N3O2. http://purl.obolibrary.org/obo/CHEBI_32859 valinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion A branched-chain amino-acid anion that has formula C5H10NO2. http://purl.obolibrary.org/obo/CHEBI_32860 valinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An alpha-amino-acid cation that has formula C5H12NO2. http://purl.obolibrary.org/obo/CHEBI_32943 octacosane http://purl.obolibrary.org/obo/CHEBI_83563 long-chain alkane A straight-chain alkane containing 28 carbon atoms. http://purl.obolibrary.org/obo/CHEBI_33289 avicide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance used to destroy bird pests (class Aves). http://purl.obolibrary.org/obo/CHEBI_33672 heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom. http://purl.obolibrary.org/obo/CHEBI_35186 terpene http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]. http://purl.obolibrary.org/obo/CHEBI_35369 pentasaccharide http://purl.obolibrary.org/obo/CHEBI_50699 oligosaccharide An oligomer comprising five monomeric monosaccharide units. http://purl.obolibrary.org/obo/CHEBI_37620 beta-L-galactose http://purl.obolibrary.org/obo/CHEBI_37619 L-galactopyranose A L-galactopyranose with a beta-configuration at the anomeric position. http://purl.obolibrary.org/obo/CHEBI_38077 polypyrrole http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound A compound composed of two or more pyrrole units. http://purl.obolibrary.org/obo/CHEBI_38263 2-amino-3-hydroxybutanoic acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An alpha-amino acid that is butanoic acid substituted by an amino group at position 2 and a hydroxy group at position 3. http://purl.obolibrary.org/obo/CHEBI_38323 cholinergic drug http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. http://purl.obolibrary.org/obo/CHEBI_38653 methylbutyric acid http://purl.obolibrary.org/obo/CHEBI_62499 methyl-branched fatty acid A methyl-branched fatty acid comprising a butyric acid core carrying a single methyl substituent. http://purl.obolibrary.org/obo/CHEBI_38717 carboxylic acid trianion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A trianion containing at least one carboxy group. http://purl.obolibrary.org/obo/CHEBI_39442 fluorescent probe http://purl.obolibrary.org/obo/CHEBI_50406 probe A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy. http://purl.obolibrary.org/obo/CHEBI_4139 D-galactopyranose http://purl.obolibrary.org/obo/CHEBI_12936 D-galactose A galactopyranose having D-configuration. http://purl.obolibrary.org/obo/CHEBI_47 (+)-syringaresinol http://purl.obolibrary.org/obo/CHEBI_49211 syringaresinol The (7alpha,7'alpha,8alpha,8'alpha)-stereoisomer of syringaresinol. http://purl.obolibrary.org/obo/CHEBI_48942 isovalerate http://purl.obolibrary.org/obo/CHEBI_58956 branched-chain saturated fatty acid anion A branched-chain saturated fatty acid anion that is the conjugate base of isovaleric acid; reported to improve ruminal fermentation and feed digestion in cattle. http://purl.obolibrary.org/obo/CHEBI_50188 provitamin http://purl.obolibrary.org/obo/CHEBI_24432 biological role A substance that can be converted into a vitamin by animal tissues. http://purl.obolibrary.org/obo/CHEBI_51151 dipolar compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case. http://purl.obolibrary.org/obo/CHEBI_52303 sterol methyltransferase inhibitor http://purl.obolibrary.org/obo/CHEBI_76871 EC 2.1.1.* (methyltransferases) inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of sterol methyltransferase. http://purl.obolibrary.org/obo/CHEBI_58573 kaempferol oxoanion http://purl.obolibrary.org/obo/CHEBI_58588 flavonol oxoanion The 3-oxoanion of kaempferol. http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion with a chain length greater than C22. http://purl.obolibrary.org/obo/CHEBI_61249 hesperetin(1-) http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion A flavonoid oxoanion that is the conjugate base of hesperetin arising from selective deprtotonation of the 7-hydroxy group. http://purl.obolibrary.org/obo/CHEBI_63470 sulfur-containing amino-acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion A sulfur-containing amino acid whose alpha-carboxylic acid group is ionized (not protonated). http://purl.obolibrary.org/obo/CHEBI_63566 pentasaccharide derivative http://purl.obolibrary.org/obo/CHEBI_63563 oligosaccharide derivative An oligosaccharide derivative that is formally obtained from a pentasaccharide. http://purl.obolibrary.org/obo/CHEBI_64047 food additive http://purl.obolibrary.org/obo/CHEBI_78295 food component Any substance which is added to food to preserve or enhance its flavour and/or appearance. http://purl.obolibrary.org/obo/CHEBI_64946 anti-HIV agent http://purl.obolibrary.org/obo/CHEBI_22587 antiviral agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. http://purl.obolibrary.org/obo/CHEBI_74224 genistein(1-) http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the conjugate base of genistein, obtained by selective deprotonation of the 7-hydroxy group. http://purl.obolibrary.org/obo/CHEBI_77484 EC 1.1.1.25 (shikimate dehydrogenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76835 EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25). http://purl.obolibrary.org/obo/CHEBI_77764 daidzein(1-) http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion A flavonoid oxoanion obtained by deprotonation of the 7-hydroxy group of daidzein. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_77791 luteolin 7-O-beta-D-glucoside(1-) http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion A flavonoid oxoanion obtained by deprotonation of the 5-hydroxy group of luteolin 7-O-beta-D-glucoside. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_78118 fatty acid anion 10:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 10 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78145 fatty alcohol 30:0 http://purl.obolibrary.org/obo/CHEBI_24026 fatty alcohol Any fatty alcohol containing 30 carbons. http://purl.obolibrary.org/obo/CHEBI_83146 Daphnia tenebrosa metabolite http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite A Daphnia metabolite produced by the species Daphnia tenebrosa. http://purl.obolibrary.org/obo/CHEBI_34687 dibutyl phthalate http://purl.obolibrary.org/obo/CHEBI_35484 phthalate ester A phthalate ester that is the diester obtained by the formal condensation of the carboxy groups of phthalic acid with two molecules of butan-1-ol. http://purl.obolibrary.org/obo/CHEBI_34698 diethyl phthalate http://purl.obolibrary.org/obo/CHEBI_35484 phthalate ester The diethyl ester of benzene-1,2-dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_34768 furfural http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde An aldehyde that is furan with the hydrogen at position 2 substituted by a formyl group. http://purl.obolibrary.org/obo/CHEBI_34833 1,3,5-trimethylbenzene http://purl.obolibrary.org/obo/CHEBI_38641 trimethylbenzene A trimethylbenzene carrying methyl substituents at positions 1, 3 and 5. http://purl.obolibrary.org/obo/CHEBI_35148 (6'S)-beta,epsilon-carotene http://purl.obolibrary.org/obo/CHEBI_28425 alpha-carotene An alpha-carotene that has formula C40H56. http://purl.obolibrary.org/obo/CHEBI_3518 Celabenzine http://purl.obolibrary.org/obo/CHEBI_52898 azamacrocycle An azamacrocycle that has formula C23H29N3O2. http://purl.obolibrary.org/obo/CHEBI_35281 onium betaine http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom. http://purl.obolibrary.org/obo/CHEBI_35568 mancude ring http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds. http://purl.obolibrary.org/obo/CHEBI_35592 2H-pyran http://purl.obolibrary.org/obo/CHEBI_35594 pyran A pyran that has formula C5H6O. http://purl.obolibrary.org/obo/CHEBI_35593 4H-pyran http://purl.obolibrary.org/obo/CHEBI_35594 pyran A pyran that has formula C5H6O. http://purl.obolibrary.org/obo/CHEBI_35673 abietane http://purl.obolibrary.org/obo/CHEBI_35190 diterpene A diterpene that has formula C20H36. http://purl.obolibrary.org/obo/CHEBI_35709 thujane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A monoterpene that has formula C10H18. http://purl.obolibrary.org/obo/CHEBI_35934 evonine http://purl.obolibrary.org/obo/CHEBI_38528 pyridine alkaloid fundamental parent A pyridine alkaloid fundamental parent that has formula C36H43NO17. http://purl.obolibrary.org/obo/CHEBI_36340 fermion http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi. http://purl.obolibrary.org/obo/CHEBI_36343 composite particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A subatomic particle known to have substructure (i.e. consisting of smaller particles). http://purl.obolibrary.org/obo/CHEBI_36344 hadron http://purl.obolibrary.org/obo/CHEBI_36343 composite particle Hadron is a subatomic particle which experiences the strong force. http://purl.obolibrary.org/obo/CHEBI_36480 bisabolane http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A terpenoid fundamental parent that has formula C15H30. http://purl.obolibrary.org/obo/CHEBI_36522 eudesmane http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A terpenoid fundamental parent that has formula C15H28. http://purl.obolibrary.org/obo/CHEBI_36539 kaurane http://purl.obolibrary.org/obo/CHEBI_35190 diterpene A diterpene that has formula C20H34. http://purl.obolibrary.org/obo/CHEBI_36562 main-group coordination entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity A coordination entity in which the central atom to which the ligands are attached comes from groups 1, 2, 13, 14, 15, 16, 17, or 18 of the periodic table. http://purl.obolibrary.org/obo/CHEBI_36611 fenchane http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent A monoterpene that is bicyclo[2.2.1]heptane substituted by methy groups at positions 1, 3 and 3. http://purl.obolibrary.org/obo/CHEBI_36756 farnesane http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10. http://purl.obolibrary.org/obo/CHEBI_37605 octadec-9-ene http://purl.obolibrary.org/obo/CHEBI_37606 octadecene An octadecene that has formula C18H36. http://purl.obolibrary.org/obo/CHEBI_42491 flavone http://purl.obolibrary.org/obo/CHEBI_24043 flavones The simplest member of the class of flavones that consists of 4H-chromen-4-one bearing a phenyl substituent at position 2. http://purl.obolibrary.org/obo/CHEBI_43572 kojic acid http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A pyranone that is 4H-pyran substituted by a hydroxy group at position 5, a hydroxymethyl group at position 2 and an oxo group at position 4. It has been isolated from the fungus Aspergillus oryzae. http://purl.obolibrary.org/obo/CHEBI_48343 disulfide http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity Compounds of structure RSSR'. http://purl.obolibrary.org/obo/CHEBI_51269 acenes http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives. http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. http://purl.obolibrary.org/obo/CHEBI_5254 galactolipid http://purl.obolibrary.org/obo/CHEBI_33563 glycolipid A glycolipid and which the glyco component is specified as galactosyl. http://purl.obolibrary.org/obo/CHEBI_63046 emulsifier http://purl.obolibrary.org/obo/CHEBI_51086 chemical role The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability. http://purl.obolibrary.org/obo/CHEBI_76835 EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76726 EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*). http://purl.obolibrary.org/obo/CHEBI_76840 EC 1.14.99.* (miscellaneous oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any enzyme in the EC 1.14.99.* (miscellaneous) category. http://purl.obolibrary.org/obo/CHEBI_60038 flavonoid oxoanion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion Any anion arising from deprotonation of at least one OH group in a flavonoid compound. http://purl.obolibrary.org/obo/CHEBI_60521 indole alkaloid cation http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion Any cation arising from protonation of at least one of the amino functions in an indole alkaloid. http://purl.obolibrary.org/obo/CHEBI_69579 hederagenin http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A sapogenin that is olean-12-en-28-oic acid substituted by hydroxy groups at positions 3 and 23 (the 3beta stereoisomer). http://purl.obolibrary.org/obo/CHEBI_84948 11,12-saturated fatty acyl-CoA(4-) http://purl.obolibrary.org/obo/CHEBI_77636 fatty acyl-CoA(4-) Any fatty acyl-CoA(4-) in which the 11-12 bond of the fatty acyl group is saturated. This is needed for a reaction together with CHEBI:84947 http://purl.obolibrary.org/obo/CHEBI_90726 3-oxoacyl-CoA(4-) http://purl.obolibrary.org/obo/CHEBI_58342 acyl-CoA(4-) An acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of any 3-oxoacyl-CoA; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_6451 Licarin A http://purl.obolibrary.org/obo/CHEBI_35259 benzofurans A benzofuran that has formula C20H22O4. http://purl.obolibrary.org/obo/CHEBI_64557 trans-sinapyl alcohol http://purl.obolibrary.org/obo/CHEBI_28813 sinapyl alcohol Sinapyl alcohol in which the configuration of the propenyl double bond is E. It is one of the main monolignols. http://purl.obolibrary.org/obo/CHEBI_65321 terpenoid indole alkaloid http://purl.obolibrary.org/obo/CHEBI_38958 indole alkaloid An indole alkaloid which is biosynthesised from L-tryptophan and isoprenoid building blocks. http://purl.obolibrary.org/obo/CHEBI_65460 avicularin http://purl.obolibrary.org/obo/CHEBI_76424 quercetin O-glycoside A quercetin O-glycoside in which an alpha-L-arabinofuranosyl residue is attached at position 3 of quercetin via a glycosidic linkage. It is isolated particularly from Juglans regia and Foeniculum vulgare. http://purl.obolibrary.org/obo/CHEBI_66682 maslinic acid http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. http://purl.obolibrary.org/obo/CHEBI_75596 EC 5.* (isomerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*). http://purl.obolibrary.org/obo/CHEBI_75603 EC 6.* (ligase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. http://purl.obolibrary.org/obo/CHEBI_75604 EC 6.4.* (C-C bond-forming ligase) inhibitor http://purl.obolibrary.org/obo/CHEBI_75603 EC 6.* (ligase) inhibitor A ligase inhibitor that interferes with the action of a C-C bond-forming ligase (EC 6.4.*.*). http://purl.obolibrary.org/obo/CHEBI_75630 procyanidin B3 http://purl.obolibrary.org/obo/CHEBI_72010 hydroxyflavan A proanthocyanidin consisting of two molecules of (+)-catechin joined by a bond between positions 4 and 8' in alpha-configuration. It can be found in red wine, in barley, in beer, in peach or in Jatropha macrantha, the Huanarpo Macho. http://purl.obolibrary.org/obo/CHEBI_75632 procyanidin B2 http://purl.obolibrary.org/obo/CHEBI_72010 hydroxyflavan A proanthocyanidin consisting of two molecules of (-)-epicatechin joined by a bond between positions 4 and 8' in a beta-configuration. Procyanidin B2 can be found in Cinchona pubescens (Chinchona, in the rind, bark and cortex), in Cinnamomum verum (Ceylon cinnamon, in the rind, bark and cortex), in Crataegus monogyna (Common hawthorn, in the flower and blossom), in Uncaria guianensis (Cat's claw, in the root), in Vitis vinifera (Common grape vine, in the leaf), in Litchi chinensis (litchi, in the pericarp), in the apple, in Ecdysanthera utilis and in red wine. http://purl.obolibrary.org/obo/CHEBI_75787 prokaryotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea. http://purl.obolibrary.org/obo/CHEBI_7602 nobiletin http://purl.obolibrary.org/obo/CHEBI_25241 methoxyflavone A methoxyflavone that is flavone substituted by methoxy groups at positions 5, 6, 7, 8, 3' and 4' respectively. http://purl.obolibrary.org/obo/CHEBI_76024 lacceroate http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion A very long-chain fatty acid anion that is the conjugate base of lacceroic acid, obtained by deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_76125 (+)-epicatechin http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol A catechin that is flavan carrying five hydroxy substituents at positions 3, 3', 4', 5 and 7 (the 2S,3S-stereoisomer). http://purl.obolibrary.org/obo/CHEBI_76215 lacceroic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain saturated fatty acid that is dotriacontane in which one of the methyl groups has been oxidised to the corresponding carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_76414 propellant http://purl.obolibrary.org/obo/CHEBI_33232 application A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans. http://purl.obolibrary.org/obo/CHEBI_76655 EC 2.1.* (C1-transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*). http://purl.obolibrary.org/obo/CHEBI_76661 EC 2.3.* (acyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*). http://purl.obolibrary.org/obo/CHEBI_76697 EC 5.99.* (other isomerases) inhibitor http://purl.obolibrary.org/obo/CHEBI_75596 EC 5.* (isomerase) inhibitor An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*). http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*). http://purl.obolibrary.org/obo/CHEBI_76726 EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*). http://purl.obolibrary.org/obo/CHEBI_76737 EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on diphenols and related substances as donors (EC 1.10.*.*). http://purl.obolibrary.org/obo/CHEBI_76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*). http://purl.obolibrary.org/obo/CHEBI_76740 EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*. http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*). http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*). http://purl.obolibrary.org/obo/CHEBI_76834 EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*). http://purl.obolibrary.org/obo/CHEBI_76938 EC 3.6.4.* (hydrolases acting on ATP; involved in cellular and subcellular movement) inhibitor http://purl.obolibrary.org/obo/CHEBI_73216 EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme acting on ATP and involved in cellular and subcellular movement (EC 3.6.4.*). http://purl.obolibrary.org/obo/CHEBI_77019 EC 1.10.99.* (oxidoreductases acting on diphenols and related substances as donors, other acceptors) inhibitor http://purl.obolibrary.org/obo/CHEBI_76737 EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme in the EC 1.10.99.* category. http://purl.obolibrary.org/obo/CHEBI_83795 3-oxolacceroyl-CoA(4-) http://purl.obolibrary.org/obo/CHEBI_84948 11,12-saturated fatty acyl-CoA(4-) A 3-oxo-fatty acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of 3-oxolacceroyl-CoA; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_84268 nonanal http://purl.obolibrary.org/obo/CHEBI_35746 fatty aldehyde A fatty aldehyde formally arising from reduction of nonanoic acis. Metabolite observed in cancer metabolism. http://purl.obolibrary.org/obo/CHEBI_84304 cholesteryl myristate http://purl.obolibrary.org/obo/CHEBI_17002 cholesterol ester A cholesterol ester obtained by the formal condensation of the hydroxy group of cholesterol with the carboxy group of myristic acid. http://purl.obolibrary.org/obo/CHEBI_84584 3-oxolacceroyl-CoA http://purl.obolibrary.org/obo/CHEBI_15489 3-oxo-fatty acyl-CoA A 3-oxo-fatty acyl-CoA obtained from the formal condensation of the thiol group of coenzyme A with the carboxy group of 3-oxolacceroic acid. http://purl.obolibrary.org/obo/CHEBI_84932 ethyl hexadecanoate http://purl.obolibrary.org/obo/CHEBI_25835 hexadecanoate ester A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of palmitic acid with the hydroxy group of ethanol. http://purl.obolibrary.org/obo/CHEBI_84940 ethyl oleate http://purl.obolibrary.org/obo/CHEBI_13209 long-chain fatty acid ethyl ester A long-chain fatty acid ethyl ester resulting from the formal condensation of the carboxy group of oleic acid with the hydroxy group of ethanol. http://purl.obolibrary.org/obo/CHEBI_85048 EC 1.10.3.* (oxidoreductase acting on diphenols and related substances as donors with oxygen as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76737 EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor An EC 1.10.* (oxidoreductase acting on diphenols and related substances as donors) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.10.3.*). http://purl.obolibrary.org/obo/UBERON_0003071 eye primordium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles. http://purl.obolibrary.org/obo/UBERON_0035804 future mouth http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The primordial mouth region of the developing head. http://purl.obolibrary.org/obo/OAE_0000601 vomiting AE http://purl.obolibrary.org/obo/OAE_0000554 abnormal digestion AE regurgitation AE http://purl.obolibrary.org/obo/OAE_0000626 double vision AE http://purl.obolibrary.org/obo/OAE_0000578 abnormal vision AE diplopia AE http://purl.obolibrary.org/obo/OAE_0003230 behavior abnormal quality http://purl.obolibrary.org/obo/PATO_0000186 behavioral quality a behavioral quality where the behavior in an organism is abnormal. http://purl.obolibrary.org/obo/TCMDPO_0000333 Tiger Bone TCD http://purl.obolibrary.org/obo/TCMDPO_0000036 祛风湿强筋骨药 虎骨 http://purl.obolibrary.org/obo/TCMDPO_0000229 Nux Vomica TCD http://purl.obolibrary.org/obo/TCMDPO_0000046 活血疗伤药 马钱子 http://purl.obolibrary.org/obo/TCMDPO_0000157 Doubleteeth Pubescent Angelica Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 独活 http://purl.obolibrary.org/obo/TCMDPO_0000331 Fourstamen Stephania Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 粉防己 http://purl.obolibrary.org/obo/TCMDPO_0000192 Prepared Common Monkshood Branched Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000010 温里药 附子 http://purl.obolibrary.org/obo/TCMDPO_0000339 Ovientvine Stem TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 青风藤 http://purl.obolibrary.org/obo/TCMDPO_0000015 活血化瘀药 http://purl.obolibrary.org/obo/TCMDPO_0000001 中药饮片 Promoting Blood Circulation and Removing Blood Stasis Drugs http://purl.obolibrary.org/obo/TCMDPO_0000001 中药饮片 http://purl.obolibrary.org/obo/DRON_00000005 drug product TCM decoction pieces http://purl.obolibrary.org/obo/TCMDPO_0000007 祛风湿药 http://purl.obolibrary.org/obo/TCMDPO_0000001 中药饮片 Dispelling Pathogenic Wind and Dampeness Drugs http://purl.obolibrary.org/obo/TCMDPO_0000010 温里药 http://purl.obolibrary.org/obo/TCMDPO_0000001 中药饮片 Warming Interior Drug http://purl.obolibrary.org/obo/TCMDPO_0000020 补虚药 http://purl.obolibrary.org/obo/TCMDPO_0000001 中药饮片 Supplementing and Boosting Drugs http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 http://purl.obolibrary.org/obo/TCMDPO_0000007 祛风湿药 Wind-damp Dispelling and Cold-dispersing Drugs http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 http://purl.obolibrary.org/obo/TCMDPO_0000007 祛风湿药 Winddamp-dispelling and Heat-clearing Drugs http://purl.obolibrary.org/obo/TCMDPO_0000036 祛风湿强筋骨药 http://purl.obolibrary.org/obo/TCMDPO_0000007 祛风湿药 Winddamp-dispelling and Tendon-bone-strengthening Drugs http://purl.obolibrary.org/obo/TCMDPO_0000057 补血药 http://purl.obolibrary.org/obo/TCMDPO_0000020 补虚药 Blood-supplementing Drugs http://purl.obolibrary.org/obo/TCMDPO_0000063 四气（中药） http://purl.obolibrary.org/obo/BFO_0000019 quality Four Natures (TCD) http://purl.obolibrary.org/obo/TCMDPO_0000064 中药五味 http://purl.obolibrary.org/obo/BFO_0000019 quality Five Flavours (TCD) http://purl.obolibrary.org/obo/TCMDPO_0000152 Black-tail Snake TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 乌梢蛇 http://purl.obolibrary.org/obo/TCMDPO_0000155 Paniculate Swallowwort Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 Paniculate Swallowwort Root http://purl.obolibrary.org/obo/TCMDPO_0000158 Oriental Variegated Coralbean Bark TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 海桐皮 http://purl.obolibrary.org/obo/TCMDPO_0000160 Siegesbeckia Herb TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 豨莶草 http://purl.obolibrary.org/obo/TCMDPO_0000161 Mulberry Twig TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 桑枝 http://purl.obolibrary.org/obo/TCMDPO_0000163 Largeleaf Gentian Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 秦艽 http://purl.obolibrary.org/obo/TCMDPO_0000165 Obscured Homalomena Rhizome TCD http://purl.obolibrary.org/obo/TCMDPO_0000036 祛风湿强筋骨药 千年健 http://purl.obolibrary.org/obo/TCMDPO_0000288 Debark Peony Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000057 补血药 白芍 http://purl.obolibrary.org/obo/TCMDPO_0000328 Common Threewingnut Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 雷公藤 http://purl.obolibrary.org/obo/TCMDPO_0000330 Silk-worm Droppings TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 Silk-worm Droppings http://purl.obolibrary.org/obo/TCMDPO_0000332 Kadsura Pepper Stem TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 海风藤 http://purl.obolibrary.org/obo/TCMDPO_0000336 Common Floweringqince Fruit TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 木瓜 http://purl.obolibrary.org/obo/TCMDPO_0000338 Wooly Datchmanspipe Herb TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 Wooly Datchmanspipe Herb http://purl.obolibrary.org/obo/TCMDPO_0000329 Tripterygii Hypoglauci Radix TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 昆明山海棠 http://purl.obolibrary.org/obo/TCMDPO_0000168 Acanthopanax Root Bark TCD http://purl.obolibrary.org/obo/TCMDPO_0000036 祛风湿强筋骨药 五加皮 http://purl.obolibrary.org/obo/TCMDPO_0000159 Harlequin Glorybower Leaf TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 臭梧桐 http://purl.obolibrary.org/obo/TCMDPO_0000167 Chinese Taxillus Herb TCD http://purl.obolibrary.org/obo/TCMDPO_0000036 祛风湿强筋骨药 桑寄生 http://purl.obolibrary.org/obo/TCMDPO_0000046 活血疗伤药 http://purl.obolibrary.org/obo/TCMDPO_0000015 活血化瘀药 Blood-activating and Trauma-curing Drugs http://purl.obolibrary.org/obo/TCMDPO_0000156 Chinese Clematis Root TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 威灵仙 http://purl.obolibrary.org/obo/TCMDPO_0000334 Chinese Starjasmine Stem TCD http://purl.obolibrary.org/obo/TCMDPO_0000035 祛风湿清热药 络石藤 http://purl.obolibrary.org/obo/TCMDPO_0000337 Chinese Pine Nodular Branch TCD http://purl.obolibrary.org/obo/TCMDPO_0000034 祛风湿散寒药 松节 http://purl.obolibrary.org/obo/CHEBI_23847 diterpene alkaloid http://purl.obolibrary.org/obo/CHEBI_26871 terpene alkaloid http://purl.obolibrary.org/obo/CHEBI_49193 diterpene lactone http://purl.obolibrary.org/obo/CHEBI_37668 terpene lactone http://purl.obolibrary.org/obo/CHEBI_24688 monohydroxycinnamic acid http://purl.obolibrary.org/obo/CHEBI_24689 hydroxycinnamic acid http://purl.obolibrary.org/obo/CHEBI_37668 terpene lactone http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid http://purl.obolibrary.org/obo/CHEBI_23243 cineole http://purl.obolibrary.org/obo/CHEBI_37407 cyclic ether http://purl.obolibrary.org/obo/CHEBI_22912 bornane monoterpenoid http://purl.obolibrary.org/obo/CHEBI_25409 monoterpenoid http://purl.obolibrary.org/obo/CHEBI_25186 p-menthane monoterpenoid http://purl.obolibrary.org/obo/CHEBI_25409 monoterpenoid http://purl.obolibrary.org/obo/CHEBI_36739 fenchane monoterpenoid http://purl.obolibrary.org/obo/CHEBI_25409 monoterpenoid http://purl.obolibrary.org/obo/CHEBI_37038 purine ribonucleoside 5'-diphosphate http://purl.obolibrary.org/obo/CHEBI_37075 ribonucleoside 5'-diphosphate http://purl.obolibrary.org/obo/CHEBI_22728 benzopyrrole http://purl.obolibrary.org/obo/CHEBI_38180 polycyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_38298 benzodioxoles http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_35570 mancude organic heterobicyclic parent http://purl.obolibrary.org/obo/CHEBI_35571 mancude organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_38606 cyclopentapyran http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_35875 imidazopyrimidine http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_17187 pinene http://purl.obolibrary.org/obo/CHEBI_35187 monoterpene http://purl.obolibrary.org/obo/CHEBI_35789 oxo steroid http://purl.obolibrary.org/obo/CHEBI_17087 ketone http://purl.obolibrary.org/obo/CHEBI_35788 seco-steroid http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_50403 ergostanoid http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_47880 steroid ester http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_37572 alpha-L-arabinofuranoside http://purl.obolibrary.org/obo/CHEBI_35376 alpha-L-arabinoside http://purl.obolibrary.org/obo/CHEBI_24405 glycosylglucose http://purl.obolibrary.org/obo/CHEBI_36233 disaccharide http://purl.obolibrary.org/obo/CHEBI_35428 ortho-fused bicyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33637 ortho-fused compound http://purl.obolibrary.org/obo/CHEBI_39205 dibenzopyrrole http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound http://purl.obolibrary.org/obo/CHEBI_26151 piperidines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_23232 chromenes http://purl.obolibrary.org/obo/CHEBI_38443 1-benzopyran http://purl.obolibrary.org/obo/CHEBI_33670 heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_33661 monocyclic compound http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_49103 drug metabolite http://purl.obolibrary.org/obo/CHEBI_76967 human xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_36147 oxo dicarboxylate http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_26092 phthalate http://purl.obolibrary.org/obo/CHEBI_22712 benzenes http://purl.obolibrary.org/obo/CHEBI_35484 phthalate ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester http://purl.obolibrary.org/obo/CHEBI_26288 propanediol http://purl.obolibrary.org/obo/CHEBI_13643 glycol http://purl.obolibrary.org/obo/CHEBI_35348 3beta-sterol http://purl.obolibrary.org/obo/CHEBI_36836 3beta-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35740 liposaccharide http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative http://purl.obolibrary.org/obo/CHEBI_33983 deoxymannose http://purl.obolibrary.org/obo/CHEBI_23628 deoxyhexose http://purl.obolibrary.org/obo/CHEBI_36085 trihydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_24675 hydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_33408 pnictogen oxoacid http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound http://purl.obolibrary.org/obo/CHEBI_35115 elemental manganese http://purl.obolibrary.org/obo/CHEBI_25154 manganese molecular entity http://purl.obolibrary.org/obo/CHEBI_35219 plant growth retardant http://purl.obolibrary.org/obo/CHEBI_26155 plant growth regulator http://purl.obolibrary.org/obo/CHEBI_37015 ribonucleoside 5'-phosphate http://purl.obolibrary.org/obo/CHEBI_16701 nucleoside 5'-phosphate http://purl.obolibrary.org/obo/CHEBI_33721 carbohydrate acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_51447 organic univalent group http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_51446 organic divalent group http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_22289 aldaric acid anion http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_22599 arabinose http://purl.obolibrary.org/obo/CHEBI_33916 aldopentose http://purl.obolibrary.org/obo/CHEBI_33666 polycyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_24163 galactoside http://purl.obolibrary.org/obo/CHEBI_35313 hexoside http://purl.obolibrary.org/obo/CHEBI_24278 glucoside http://purl.obolibrary.org/obo/CHEBI_35313 hexoside http://purl.obolibrary.org/obo/CHEBI_132943 aspartate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion http://purl.obolibrary.org/obo/CHEBI_36300 tricarboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_35753 tricarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_27092 tricarboxylic acid trianion http://purl.obolibrary.org/obo/CHEBI_38717 carboxylic acid trianion http://purl.obolibrary.org/obo/CHEBI_36299 tricarboxylic acid monoanion http://purl.obolibrary.org/obo/CHEBI_35753 tricarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_36853 hydroxy seco-steroid http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_49302 2-hydroxy monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35868 hydroxy monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_36123 cyclitol carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33598 carbocyclic compound http://purl.obolibrary.org/obo/CHEBI_26561 ribonucleotide http://purl.obolibrary.org/obo/CHEBI_26562 ribose phosphate http://purl.obolibrary.org/obo/CHEBI_29075 mononucleotide http://purl.obolibrary.org/obo/CHEBI_36976 nucleotide http://purl.obolibrary.org/obo/CHEBI_131906 4-pyranones http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone http://purl.obolibrary.org/obo/CHEBI_27171 organic heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33672 heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_35259 benzofurans http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_51914 organic heterohexacyclic compound http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_52157 organic heteroheptacyclic compound http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_22727 benzopyran http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_38163 organic heterotetracyclic compound http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_38164 organic heteropentacyclic compound http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_48360 amphiprotic solvent http://purl.obolibrary.org/obo/CHEBI_48359 protophilic solvent http://purl.obolibrary.org/obo/CHEBI_36087 cinnamate ester http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid http://purl.obolibrary.org/obo/CHEBI_37096 adenosine 5'-phosphate http://purl.obolibrary.org/obo/CHEBI_37021 purine ribonucleoside 5'-monophosphate http://purl.obolibrary.org/obo/CHEBI_22251 adenosine bisphosphate http://purl.obolibrary.org/obo/CHEBI_61079 ribonucleoside bisphosphate http://purl.obolibrary.org/obo/CHEBI_33798 tetraric acid anion http://purl.obolibrary.org/obo/CHEBI_22289 aldaric acid anion http://purl.obolibrary.org/obo/CHEBI_26933 tetraric acid http://purl.obolibrary.org/obo/CHEBI_66873 C4-dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_30356 isobutyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_45557 sec-butyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_30353 isopropyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_25696 organic anion http://purl.obolibrary.org/obo/CHEBI_25699 organic ion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion http://purl.obolibrary.org/obo/CHEBI_36914 inorganic ion http://purl.obolibrary.org/obo/CHEBI_35376 alpha-L-arabinoside http://purl.obolibrary.org/obo/CHEBI_22601 arabinoside http://purl.obolibrary.org/obo/CHEBI_22702 benzamides http://purl.obolibrary.org/obo/CHEBI_22645 arenecarboxamide http://purl.obolibrary.org/obo/CHEBI_38443 1-benzopyran http://purl.obolibrary.org/obo/CHEBI_22727 benzopyran http://purl.obolibrary.org/obo/CHEBI_33609 elemental boron http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity http://purl.obolibrary.org/obo/CHEBI_35155 elemental calcium http://purl.obolibrary.org/obo/CHEBI_22985 calcium molecular entity http://purl.obolibrary.org/obo/CHEBI_35163 cyclic carotene http://purl.obolibrary.org/obo/CHEBI_23042 carotene http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation http://purl.obolibrary.org/obo/CHEBI_25430 monoatomic polycation http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_25414 monoatomic monocation http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_30412 monoatomic dication http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_20961 D-galactoside http://purl.obolibrary.org/obo/CHEBI_24163 galactoside http://purl.obolibrary.org/obo/CHEBI_35436 D-glucoside http://purl.obolibrary.org/obo/CHEBI_24278 glucoside http://purl.obolibrary.org/obo/CHEBI_37711 phosphatidyl oligosaccharide http://purl.obolibrary.org/obo/CHEBI_24385 glycoglycerolipid http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_52208 biophysical role http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_52211 physiological role http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_33670 heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_27115 trihydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_24676 hydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_24031 ferulic acids http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether http://purl.obolibrary.org/obo/CHEBI_33461 phosphorus oxoanion http://purl.obolibrary.org/obo/CHEBI_33459 pnictogen oxoanion http://purl.obolibrary.org/obo/CHEBI_36914 inorganic ion http://purl.obolibrary.org/obo/CHEBI_24870 ion http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_33465 elemental pnictogen http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_27365 zinc ion http://purl.obolibrary.org/obo/CHEBI_37253 elemental zinc http://purl.obolibrary.org/obo/CHEBI_24867 monoatomic ion http://purl.obolibrary.org/obo/CHEBI_33238 monoatomic entity http://purl.obolibrary.org/obo/CHEBI_25699 organic ion http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_33976 magnesium coordination entity http://purl.obolibrary.org/obo/CHEBI_35217 alkaline earth coordination entity http://purl.obolibrary.org/obo/CHEBI_33973 elemental magnesium http://purl.obolibrary.org/obo/CHEBI_25108 magnesium molecular entity http://purl.obolibrary.org/obo/CHEBI_33515 transition element cation http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_39124 calcium ion http://purl.obolibrary.org/obo/CHEBI_35155 elemental calcium http://purl.obolibrary.org/obo/CHEBI_33504 alkali metal cation http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_33513 alkaline earth cation http://purl.obolibrary.org/obo/CHEBI_33299 alkaline earth molecular entity http://purl.obolibrary.org/obo/CHEBI_25111 magnesium porphyrin http://purl.obolibrary.org/obo/CHEBI_38251 magnesium tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_37237 elemental molybdenum http://purl.obolibrary.org/obo/CHEBI_25370 molybdenum molecular entity http://purl.obolibrary.org/obo/CHEBI_26937 monoatomic tetracation http://purl.obolibrary.org/obo/CHEBI_25430 monoatomic polycation http://purl.obolibrary.org/obo/CHEBI_25555 nitrogen atom http://purl.obolibrary.org/obo/CHEBI_33300 pnictogen http://purl.obolibrary.org/obo/CHEBI_35555 mancude organic heteromonocyclic parent http://purl.obolibrary.org/obo/CHEBI_35571 mancude organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_26407 pyrans http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_36389 saturated organic heteromonocyclic parent http://purl.obolibrary.org/obo/CHEBI_36388 saturated organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_25703 organic phosphate http://purl.obolibrary.org/obo/CHEBI_26020 phosphate http://purl.obolibrary.org/obo/CHEBI_35580 N-oxide http://purl.obolibrary.org/obo/CHEBI_25741 oxide http://purl.obolibrary.org/obo/CHEBI_26562 ribose phosphate http://purl.obolibrary.org/obo/CHEBI_25900 aldopentose phosphate http://purl.obolibrary.org/obo/CHEBI_36360 phosphorus oxoacids and derivatives http://purl.obolibrary.org/obo/CHEBI_26082 phosphorus molecular entity http://purl.obolibrary.org/obo/CHEBI_33464 elemental phosphorus http://purl.obolibrary.org/obo/CHEBI_33465 elemental pnictogen http://purl.obolibrary.org/obo/CHEBI_25216 metalloporphyrin http://purl.obolibrary.org/obo/CHEBI_33909 metallotetrapyrrole http://purl.obolibrary.org/obo/CHEBI_37247 elemental potassium http://purl.obolibrary.org/obo/CHEBI_26217 potassium molecular entity http://purl.obolibrary.org/obo/CHEBI_26284 propane-1,2-diols http://purl.obolibrary.org/obo/CHEBI_26288 propanediol http://purl.obolibrary.org/obo/CHEBI_26396 purine ribonucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_17668 ribonucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_26397 purine ribonucleoside monophosphate http://purl.obolibrary.org/obo/CHEBI_26558 ribonucleoside monophosphate http://purl.obolibrary.org/obo/CHEBI_37021 purine ribonucleoside 5'-monophosphate http://purl.obolibrary.org/obo/CHEBI_37010 ribonucleoside 5'-monophosphate http://purl.obolibrary.org/obo/CHEBI_27848 alpha-L-rhamnoside http://purl.obolibrary.org/obo/CHEBI_26547 rhamnoside http://purl.obolibrary.org/obo/CHEBI_37010 ribonucleoside 5'-monophosphate http://purl.obolibrary.org/obo/CHEBI_37015 ribonucleoside 5'-phosphate http://purl.obolibrary.org/obo/CHEBI_36904 elemental selenium http://purl.obolibrary.org/obo/CHEBI_26628 selenium molecular entity http://purl.obolibrary.org/obo/CHEBI_37763 elemental silicon http://purl.obolibrary.org/obo/CHEBI_26677 silicon molecular entity http://purl.obolibrary.org/obo/CHEBI_26657 sesquiterpene alkaloid http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_26871 terpene alkaloid http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid http://purl.obolibrary.org/obo/CHEBI_25411 monoterpenols http://purl.obolibrary.org/obo/CHEBI_26874 terpenol http://purl.obolibrary.org/obo/CHEBI_36309 cyclic tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_47882 cyclic polypyrrole http://purl.obolibrary.org/obo/CHEBI_23045 carotenol http://purl.obolibrary.org/obo/CHEBI_27325 xanthophyll http://purl.obolibrary.org/obo/CHEBI_23443 cyclic amide http://purl.obolibrary.org/obo/CHEBI_32988 amide http://purl.obolibrary.org/obo/CHEBI_37958 dye http://purl.obolibrary.org/obo/CHEBI_33232 application http://purl.obolibrary.org/obo/CHEBI_33466 monoatomic phosphorus http://purl.obolibrary.org/obo/CHEBI_33464 elemental phosphorus http://purl.obolibrary.org/obo/CHEBI_33610 monoatomic boron http://purl.obolibrary.org/obo/CHEBI_33609 elemental boron http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_35552 heterocyclic organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_35573 organic mancude parent http://purl.obolibrary.org/obo/CHEBI_35568 mancude ring http://purl.obolibrary.org/obo/CHEBI_25585 nonmetal atom http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_33434 elemental halogen http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity http://purl.obolibrary.org/obo/CHEBI_26217 potassium molecular entity http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_22985 calcium molecular entity http://purl.obolibrary.org/obo/CHEBI_33299 alkaline earth molecular entity http://purl.obolibrary.org/obo/CHEBI_25108 magnesium molecular entity http://purl.obolibrary.org/obo/CHEBI_33299 alkaline earth molecular entity http://purl.obolibrary.org/obo/CHEBI_37133 barium molecular entity http://purl.obolibrary.org/obo/CHEBI_33299 alkaline earth molecular entity http://purl.obolibrary.org/obo/CHEBI_35217 alkaline earth coordination entity http://purl.obolibrary.org/obo/CHEBI_36562 main-group coordination entity http://purl.obolibrary.org/obo/CHEBI_37131 strontium molecular entity http://purl.obolibrary.org/obo/CHEBI_33299 alkaline earth molecular entity http://purl.obolibrary.org/obo/CHEBI_26082 phosphorus molecular entity http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33459 pnictogen oxoanion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion http://purl.obolibrary.org/obo/CHEBI_35881 pnictogen hydride http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/CHEBI_25806 oxygen molecular entity http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_26628 selenium molecular entity http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_22313 alkaline earth metal atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_22314 alkali metal atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_22744 benzyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_23378 copper cation http://purl.obolibrary.org/obo/CHEBI_37404 elemental copper http://purl.obolibrary.org/obo/CHEBI_24875 iron cation http://purl.obolibrary.org/obo/CHEBI_82663 elemental iron http://purl.obolibrary.org/obo/CHEBI_25155 manganese cation http://purl.obolibrary.org/obo/CHEBI_35115 elemental manganese http://purl.obolibrary.org/obo/CHEBI_25516 nickel cation http://purl.obolibrary.org/obo/CHEBI_60248 nickel ion http://purl.obolibrary.org/obo/CHEBI_60253 silver cation http://purl.obolibrary.org/obo/CHEBI_60247 silver ion http://purl.obolibrary.org/obo/CHEBI_37239 molybdenum cation http://purl.obolibrary.org/obo/CHEBI_37237 elemental molybdenum http://purl.obolibrary.org/obo/CHEBI_33306 carbon group element atom http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_33317 boron group element atom http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_24385 glycoglycerolipid http://purl.obolibrary.org/obo/CHEBI_33563 glycolipid http://purl.obolibrary.org/obo/CHEBI_22916 boron molecular entity http://purl.obolibrary.org/obo/CHEBI_33581 boron group molecular entity http://purl.obolibrary.org/obo/CHEBI_26677 silicon molecular entity http://purl.obolibrary.org/obo/CHEBI_33582 carbon group molecular entity http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon http://purl.obolibrary.org/obo/CHEBI_27364 zinc molecular entity http://purl.obolibrary.org/obo/CHEBI_33673 zinc group molecular entity http://purl.obolibrary.org/obo/CHEBI_33581 boron group molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33582 carbon group molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_25370 molybdenum molecular entity http://purl.obolibrary.org/obo/CHEBI_33741 chromium group molecular entity http://purl.obolibrary.org/obo/CHEBI_25154 manganese molecular entity http://purl.obolibrary.org/obo/CHEBI_33743 manganese group molecular entity http://purl.obolibrary.org/obo/CHEBI_24873 iron molecular entity http://purl.obolibrary.org/obo/CHEBI_33744 iron group molecular entity http://purl.obolibrary.org/obo/CHEBI_23377 copper molecular entity http://purl.obolibrary.org/obo/CHEBI_33745 copper group molecular entity http://purl.obolibrary.org/obo/CHEBI_33964 silver molecular entity http://purl.obolibrary.org/obo/CHEBI_33745 copper group molecular entity http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound http://purl.obolibrary.org/obo/CHEBI_33655 aromatic compound http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_38251 magnesium tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_33976 magnesium coordination entity http://purl.obolibrary.org/obo/CHEBI_25900 aldopentose phosphate http://purl.obolibrary.org/obo/CHEBI_84055 pentose phosphate http://purl.obolibrary.org/obo/CHEBI_35426 ortho-fused bicyclic arene http://purl.obolibrary.org/obo/CHEBI_35428 ortho-fused bicyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_22601 arabinoside http://purl.obolibrary.org/obo/CHEBI_35312 pentoside http://purl.obolibrary.org/obo/CHEBI_26124 phytosteroid http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_36849 6-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_33909 metallotetrapyrrole http://purl.obolibrary.org/obo/CHEBI_36309 cyclic tetrapyrrole http://purl.obolibrary.org/obo/CHEBI_26079 phosphoric acid derivative http://purl.obolibrary.org/obo/CHEBI_36359 phosphorus oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_36359 phosphorus oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_7524 nerolidol http://purl.obolibrary.org/obo/CHEBI_36757 farnesane sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_36961 chalcocarbonic acid http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound http://purl.obolibrary.org/obo/CHEBI_50312 onium compound http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_23403 coumarins http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid http://purl.obolibrary.org/obo/CHEBI_38497 respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_38496 electron-transport chain inhibitor http://purl.obolibrary.org/obo/CHEBI_25355 mitochondrial respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_38497 respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_41402 carboxymethyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_50326 sulfanylmethyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_50340 3-carbamimidamidopropyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_24712 hydroxymethyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_50329 2-carboxyethyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_50338 1H-imidazol-4-ylmethyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_50341 1-hydroxyethyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride http://purl.obolibrary.org/obo/CHEBI_35881 pnictogen hydride http://purl.obolibrary.org/obo/CHEBI_22580 anthraquinone http://purl.obolibrary.org/obo/CHEBI_46955 anthracenes http://purl.obolibrary.org/obo/CHEBI_23019 carbonyl group http://purl.obolibrary.org/obo/CHEBI_51422 organodiyl group http://purl.obolibrary.org/obo/CHEBI_22798 beta-D-glucoside http://purl.obolibrary.org/obo/CHEBI_35436 D-glucoside http://purl.obolibrary.org/obo/CHEBI_37075 ribonucleoside 5'-diphosphate http://purl.obolibrary.org/obo/CHEBI_37015 ribonucleoside 5'-phosphate http://purl.obolibrary.org/obo/CHEBI_37134 elemental barium http://purl.obolibrary.org/obo/CHEBI_37133 barium molecular entity http://purl.obolibrary.org/obo/CHEBI_39123 calcium cation http://purl.obolibrary.org/obo/CHEBI_33513 alkaline earth cation http://purl.obolibrary.org/obo/CHEBI_39125 barium cation http://purl.obolibrary.org/obo/CHEBI_33513 alkaline earth cation http://purl.obolibrary.org/obo/CHEBI_39129 strontium cation http://purl.obolibrary.org/obo/CHEBI_33513 alkaline earth cation http://purl.obolibrary.org/obo/CHEBI_39130 strontium ion http://purl.obolibrary.org/obo/CHEBI_39131 elemental strontium http://purl.obolibrary.org/obo/CHEBI_48359 protophilic solvent http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent http://purl.obolibrary.org/obo/CHEBI_48513 carbazoles http://purl.obolibrary.org/obo/CHEBI_39205 dibenzopyrrole http://purl.obolibrary.org/obo/CHEBI_38496 electron-transport chain inhibitor http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor http://purl.obolibrary.org/obo/CHEBI_50034 phellandrene http://purl.obolibrary.org/obo/CHEBI_33643 cycloalkene http://purl.obolibrary.org/obo/NCBITaxon_152363 Sinomenium acutum http://purl.obolibrary.org/obo/NCBITaxon_1461172 Menispermoideae http://purl.obolibrary.org/obo/NCBITaxon_425106 Stephania tetrandra http://purl.obolibrary.org/obo/NCBITaxon_1461172 Menispermoideae http://purl.obolibrary.org/obo/NCBITaxon_364270 Apiineae http://purl.obolibrary.org/obo/NCBITaxon_91882 campanulids http://purl.obolibrary.org/obo/NCBITaxon_183075 Sigesbeckia http://purl.obolibrary.org/obo/NCBITaxon_91882 campanulids http://purl.obolibrary.org/obo/OAE_0000123 lactation factor of adverse event http://purl.obolibrary.org/obo/OAE_0000115 intrinsic factor of adverse event http://purl.obolibrary.org/obo/OAE_0000402 abdominal pain AE http://purl.obolibrary.org/obo/OAE_0000374 pain AE http://purl.obolibrary.org/obo/OAE_0004231 kidney area percussion pain AE http://purl.obolibrary.org/obo/OAE_0000374 pain AE http://purl.obolibrary.org/obo/OAE_0000698 vasodilatation AE http://purl.obolibrary.org/obo/OAE_0000493 cardiovascular AE http://purl.obolibrary.org/obo/OAE_0000086 dermatitis AE http://purl.obolibrary.org/obo/OAE_0000543 skin AE http://purl.obolibrary.org/obo/OAE_0000582 sensory capability AE http://purl.obolibrary.org/obo/OAE_0000580 behavioral and neurological AE http://purl.obolibrary.org/obo/OAE_0000307 difficulty in walking AE http://purl.obolibrary.org/obo/OAE_0000581 movement disorder AE http://purl.obolibrary.org/obo/OAE_0000542 ataxia AE http://purl.obolibrary.org/obo/OAE_0000581 movement disorder AE http://purl.obolibrary.org/obo/OAE_0001047 toxin-induced cardiomyopathy AE http://purl.obolibrary.org/obo/OAE_0000785 cardiomyopathy AE http://purl.obolibrary.org/obo/OAE_0000808 alcohol cardiomyopathy AE http://purl.obolibrary.org/obo/OAE_0001047 toxin-induced cardiomyopathy AE http://purl.obolibrary.org/obo/TCMDPO_0000335 微寒（中药） http://purl.obolibrary.org/obo/TCMDPO_0000067 寒（中药） http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/OGMS_0000060 bodily process http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/TCMDPO_0000065 毒性 http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/BFO_0000029 site http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000027 object aggregate http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000030 object http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000029 site http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/CHEBI_38445 chromenone http://purl.obolibrary.org/obo/CHEBI_23232 chromenes http://purl.obolibrary.org/obo/CHEBI_47017 tetrahydrofuranol http://purl.obolibrary.org/obo/CHEBI_26912 oxolanes http://purl.obolibrary.org/obo/CHEBI_36091 cinnamates http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_36125 cyclitol carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_36056 furancarboxylate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_36109 piperidinecarboxylate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_36126 cyclohexenecarboxylate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_22256 adenosine phosphate http://purl.obolibrary.org/obo/CHEBI_61296 adenyl ribonucleotide http://purl.obolibrary.org/obo/CHEBI_46686 azaalkane http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound http://purl.obolibrary.org/obo/CHEBI_26849 tartaric acid http://purl.obolibrary.org/obo/CHEBI_15674 2,3-dihydroxybutanedioic acid http://purl.obolibrary.org/obo/CHEBI_33720 carbohydrate acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid http://purl.obolibrary.org/obo/CHEBI_26391 purine nucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_16862 nucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_17668 ribonucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_16862 nucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_26392 purine nucleoside monophosphate http://purl.obolibrary.org/obo/CHEBI_17188 nucleoside 5'-monophosphate http://purl.obolibrary.org/obo/CHEBI_26558 ribonucleoside monophosphate http://purl.obolibrary.org/obo/CHEBI_17188 nucleoside 5'-monophosphate http://purl.obolibrary.org/obo/CHEBI_37624 L-glucose http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_37661 glucopyranose http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_24174 galacturonan http://purl.obolibrary.org/obo/CHEBI_18154 polysaccharide http://purl.obolibrary.org/obo/CHEBI_26432 pyrimidine nucleobase http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines http://purl.obolibrary.org/obo/CHEBI_26386 purine nucleobase http://purl.obolibrary.org/obo/CHEBI_26401 purines http://purl.obolibrary.org/obo/CHEBI_25236 methoxybenzoate http://purl.obolibrary.org/obo/CHEBI_22718 benzoates http://purl.obolibrary.org/obo/CHEBI_37404 elemental copper http://purl.obolibrary.org/obo/CHEBI_23377 copper molecular entity http://purl.obolibrary.org/obo/CHEBI_28966 chlorophyll http://purl.obolibrary.org/obo/CHEBI_25111 magnesium porphyrin http://purl.obolibrary.org/obo/CHEBI_23366 compatible osmolytes http://purl.obolibrary.org/obo/CHEBI_25728 osmolyte http://purl.obolibrary.org/obo/CHEBI_42485 formyl group http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group http://purl.obolibrary.org/obo/CHEBI_15193 tartrate(2-) http://purl.obolibrary.org/obo/CHEBI_30929 2,3-dihydroxybutanedioate http://purl.obolibrary.org/obo/CHEBI_46883 carboxy group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group http://purl.obolibrary.org/obo/CHEBI_33937 macronutrient http://purl.obolibrary.org/obo/CHEBI_33284 nutrient http://purl.obolibrary.org/obo/CHEBI_27027 micronutrient http://purl.obolibrary.org/obo/CHEBI_33284 nutrient http://purl.obolibrary.org/obo/CHEBI_35131 aldose phosphate http://purl.obolibrary.org/obo/CHEBI_33447 phospho sugar http://purl.obolibrary.org/obo/CHEBI_33856 aromatic amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid http://purl.obolibrary.org/obo/CHEBI_26167 polar amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid http://purl.obolibrary.org/obo/CHEBI_26834 sulfur-containing amino acid http://purl.obolibrary.org/obo/CHEBI_33576 sulfur-containing carboxylic acid http://purl.obolibrary.org/obo/CHEBI_32613 isoleucinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation http://purl.obolibrary.org/obo/CHEBI_32833 threoninium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation http://purl.obolibrary.org/obo/CHEBI_26394 purine nucleoside http://purl.obolibrary.org/obo/CHEBI_26401 purines http://purl.obolibrary.org/obo/CHEBI_26440 pyrimidine nucleoside http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines http://purl.obolibrary.org/obo/CHEBI_26547 rhamnoside http://purl.obolibrary.org/obo/CHEBI_35315 deoxy hexoside http://purl.obolibrary.org/obo/CHEBI_35594 pyran http://purl.obolibrary.org/obo/CHEBI_26407 pyrans http://purl.obolibrary.org/obo/CHEBI_36850 6alpha-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_36849 6-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_27242 uridines http://purl.obolibrary.org/obo/CHEBI_39446 pyrimidine ribonucleosides http://purl.obolibrary.org/obo/CHEBI_26816 carbohydrate phosphate http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester http://purl.obolibrary.org/obo/CHEBI_43176 hydroxy group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_46629 oxo group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_33703 amino-acid cation http://purl.obolibrary.org/obo/CHEBI_33702 polyatomic cation http://purl.obolibrary.org/obo/UBERON_0005604 extrahepatic part of hepatic duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct http://purl.obolibrary.org/obo/NCBITaxon_228726 Vincetoxicum pycnostelma http://purl.obolibrary.org/obo/NCBITaxon_4056 Apocynaceae http://purl.obolibrary.org/obo/NCBITaxon_69389 Trachelospermum jasminoides http://purl.obolibrary.org/obo/NCBITaxon_4056 Apocynaceae http://purl.obolibrary.org/obo/NCBITaxon_450288 Piper wallichii http://purl.obolibrary.org/obo/NCBITaxon_16736 Piperales http://purl.obolibrary.org/obo/NCBITaxon_158558 Aristolochia mollissima http://purl.obolibrary.org/obo/NCBITaxon_16736 Piperales http://purl.obolibrary.org/obo/NCBITaxon_1461172 Menispermoideae http://purl.obolibrary.org/obo/NCBITaxon_41768 Ranunculales http://purl.obolibrary.org/obo/NCBITaxon_1463138 Ranunculoideae http://purl.obolibrary.org/obo/NCBITaxon_41768 Ranunculales http://purl.obolibrary.org/obo/NCBITaxon_40917 Heracleum http://purl.obolibrary.org/obo/NCBITaxon_364270 Apiineae http://purl.obolibrary.org/obo/NCBITaxon_265764 Eleutherococcus gracilistylus http://purl.obolibrary.org/obo/NCBITaxon_364270 Apiineae http://purl.obolibrary.org/obo/NCBITaxon_28545 Strychnos nux-vomica http://purl.obolibrary.org/obo/NCBITaxon_4055 Gentianales http://purl.obolibrary.org/obo/NCBITaxon_4056 Apocynaceae http://purl.obolibrary.org/obo/NCBITaxon_4055 Gentianales http://purl.obolibrary.org/obo/NCBITaxon_50765 Gentiana macrophylla http://purl.obolibrary.org/obo/NCBITaxon_4055 Gentianales http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone http://purl.obolibrary.org/obo/CHEBI_17087 ketone http://purl.obolibrary.org/obo/CHEBI_26509 quinoline alkaloid http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid http://purl.obolibrary.org/obo/CHEBI_26416 pyridine alkaloid http://purl.obolibrary.org/obo/CHEBI_26421 pyridines http://purl.obolibrary.org/obo/CHEBI_38524 spermidine alkaloid http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid http://purl.obolibrary.org/obo/CHEBI_26799 styrenes http://purl.obolibrary.org/obo/CHEBI_22712 benzenes http://purl.obolibrary.org/obo/CHEBI_38631 aminoalkylindole http://purl.obolibrary.org/obo/CHEBI_24828 indoles http://purl.obolibrary.org/obo/CHEBI_23483 cyclohexenecarboxylic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35868 hydroxy monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_24669 hydroxy carboxylic acid http://purl.obolibrary.org/obo/CHEBI_26148 piperidinemonocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_26151 piperidines http://purl.obolibrary.org/obo/CHEBI_48590 hydroxypiperidine http://purl.obolibrary.org/obo/CHEBI_26151 piperidines http://purl.obolibrary.org/obo/CHEBI_26399 purine ribonucleoside http://purl.obolibrary.org/obo/CHEBI_18254 ribonucleoside http://purl.obolibrary.org/obo/CHEBI_36757 farnesane sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_39432 furochromene http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_27314 water-soluble vitamin http://purl.obolibrary.org/obo/CHEBI_33229 vitamin http://purl.obolibrary.org/obo/CHEBI_35915 sterol ester http://purl.obolibrary.org/obo/CHEBI_47880 steroid ester http://purl.obolibrary.org/obo/CHEBI_32612 isoleucinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion http://purl.obolibrary.org/obo/CHEBI_32832 threoninate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion http://purl.obolibrary.org/obo/CHEBI_38180 polycyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_38179 monocyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_33570 benzenediols http://purl.obolibrary.org/obo/CHEBI_33853 phenols http://purl.obolibrary.org/obo/CHEBI_49235 bisabolene http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene http://purl.obolibrary.org/obo/CHEBI_49289 humulene http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene http://purl.obolibrary.org/obo/CHEBI_25872 pentacyclic triterpenoid http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound http://purl.obolibrary.org/obo/CHEBI_66987 radiation protective agent http://purl.obolibrary.org/obo/CHEBI_50267 protective agent http://purl.obolibrary.org/obo/CHEBI_6060 Isosorbide http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_3815 Collagen http://purl.obolibrary.org/obo/CHEBI_60027 polymer http://purl.obolibrary.org/obo/CHEBI_16733 D-alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_83925 non-proteinogenic alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_39446 pyrimidine ribonucleosides http://purl.obolibrary.org/obo/CHEBI_18254 ribonucleoside http://purl.obolibrary.org/obo/CHEBI_28383 alpha,omega-dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33729 tetritol http://purl.obolibrary.org/obo/CHEBI_17522 alditol http://purl.obolibrary.org/obo/CHEBI_26534 retinals http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde http://purl.obolibrary.org/obo/CHEBI_50196 dihydroxybenzaldehyde http://purl.obolibrary.org/obo/CHEBI_22698 benzaldehydes http://purl.obolibrary.org/obo/CHEBI_52618 2-hydroxy carboxylic acid http://purl.obolibrary.org/obo/CHEBI_24669 hydroxy carboxylic acid http://purl.obolibrary.org/obo/CHEBI_16862 nucleoside diphosphate http://purl.obolibrary.org/obo/CHEBI_25608 nucleoside phosphate http://purl.obolibrary.org/obo/CHEBI_17188 nucleoside 5'-monophosphate http://purl.obolibrary.org/obo/CHEBI_25608 nucleoside phosphate http://purl.obolibrary.org/obo/CHEBI_37123 nucleoside bisphosphate http://purl.obolibrary.org/obo/CHEBI_25608 nucleoside phosphate http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_16640 D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid http://purl.obolibrary.org/obo/CHEBI_37711 phosphatidyl oligosaccharide http://purl.obolibrary.org/obo/CHEBI_51121 fluorescent dye http://purl.obolibrary.org/obo/CHEBI_37958 dye http://purl.obolibrary.org/obo/CHEBI_48355 non-polar solvent http://purl.obolibrary.org/obo/CHEBI_46787 solvent http://purl.obolibrary.org/obo/CHEBI_28034 beta-D-galactoside http://purl.obolibrary.org/obo/CHEBI_20961 D-galactoside http://purl.obolibrary.org/obo/CHEBI_37240 adenosine 3',5'-bisphosphate http://purl.obolibrary.org/obo/CHEBI_22251 adenosine bisphosphate http://purl.obolibrary.org/obo/CHEBI_22260 adenosines http://purl.obolibrary.org/obo/CHEBI_26399 purine ribonucleoside http://purl.obolibrary.org/obo/CHEBI_26587 rutinoside http://purl.obolibrary.org/obo/CHEBI_26548 rhamnosylglucoside http://purl.obolibrary.org/obo/CHEBI_51959 organic tricyclic compound http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound http://purl.obolibrary.org/obo/CHEBI_38525 terpene alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35506 alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_38482 indole alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35506 alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_38515 isoquinoline alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35506 alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_38514 quinoline alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35506 alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_38528 pyridine alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35506 alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_36892 elemental fluorine http://purl.obolibrary.org/obo/CHEBI_33434 elemental halogen http://purl.obolibrary.org/obo/CHEBI_33340 zinc group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_33352 manganese group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_33356 iron group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_33350 chromium group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_33366 copper group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_33661 monocyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_35295 homopolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_35293 fused compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_35427 ortho-fused polycyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33637 ortho-fused compound http://purl.obolibrary.org/obo/CHEBI_33842 aromatic annulene http://purl.obolibrary.org/obo/CHEBI_33847 monocyclic arene http://purl.obolibrary.org/obo/CHEBI_33664 monocyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_36688 heterotricyclic compound http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33608 hydrogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33673 zinc group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33741 chromium group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33743 manganese group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33744 iron group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33745 copper group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_37176 mononuclear parent hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_37175 organic hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation http://purl.obolibrary.org/obo/CHEBI_33703 amino-acid cation http://purl.obolibrary.org/obo/CHEBI_35296 ortho-fused polycyclic arene http://purl.obolibrary.org/obo/CHEBI_35427 ortho-fused polycyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33966 elemental silver http://purl.obolibrary.org/obo/CHEBI_33964 silver molecular entity http://purl.obolibrary.org/obo/CHEBI_39128 magnesium ion http://purl.obolibrary.org/obo/CHEBI_33973 elemental magnesium http://purl.obolibrary.org/obo/CHEBI_35662 terpenoid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_35506 alkaloid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_39126 barium ion http://purl.obolibrary.org/obo/CHEBI_37134 elemental barium http://purl.obolibrary.org/obo/CHEBI_47019 dihydroxytetrahydrofuran http://purl.obolibrary.org/obo/CHEBI_47017 tetrahydrofuranol http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_9694 Panthera tigris http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_16736 Piperales http://purl.obolibrary.org/obo/NCBITaxon_1437183 Mesangiospermae http://purl.obolibrary.org/obo/NCBITaxon_71240 eudicotyledons http://purl.obolibrary.org/obo/NCBITaxon_1437183 Mesangiospermae http://purl.obolibrary.org/obo/NCBITaxon_714477 Homalomena occulta http://purl.obolibrary.org/obo/NCBITaxon_1437183 Mesangiospermae http://purl.obolibrary.org/obo/NCBITaxon_227910 Taxillus sutchuenensis http://purl.obolibrary.org/obo/NCBITaxon_1437201 Pentapetalae http://purl.obolibrary.org/obo/NCBITaxon_71274 asterids http://purl.obolibrary.org/obo/NCBITaxon_1437201 Pentapetalae http://purl.obolibrary.org/obo/NCBITaxon_71275 rosids http://purl.obolibrary.org/obo/NCBITaxon_1437201 Pentapetalae http://purl.obolibrary.org/obo/NCBITaxon_35924 Paeonia lactiflora http://purl.obolibrary.org/obo/NCBITaxon_1437201 Pentapetalae http://purl.obolibrary.org/obo/NCBITaxon_1437183 Mesangiospermae http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_8587 Ptyas dhumnades http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_7091 Bombyx mori http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_36603 Chaenomeles http://purl.obolibrary.org/obo/NCBITaxon_3744 Rosales http://purl.obolibrary.org/obo/NCBITaxon_3498 Morus alba http://purl.obolibrary.org/obo/NCBITaxon_3744 Rosales http://purl.obolibrary.org/obo/NCBITaxon_41768 Ranunculales http://purl.obolibrary.org/obo/NCBITaxon_71240 eudicotyledons http://purl.obolibrary.org/obo/NCBITaxon_1437201 Pentapetalae http://purl.obolibrary.org/obo/NCBITaxon_71240 eudicotyledons http://purl.obolibrary.org/obo/NCBITaxon_91882 campanulids http://purl.obolibrary.org/obo/NCBITaxon_71274 asterids http://purl.obolibrary.org/obo/NCBITaxon_91888 lamiids http://purl.obolibrary.org/obo/NCBITaxon_71274 asterids http://purl.obolibrary.org/obo/NCBITaxon_91835 fabids http://purl.obolibrary.org/obo/NCBITaxon_71275 rosids http://purl.obolibrary.org/obo/NCBITaxon_434238 Pistacia terebinthus http://purl.obolibrary.org/obo/NCBITaxon_71275 rosids http://purl.obolibrary.org/obo/NCBITaxon_3744 Rosales http://purl.obolibrary.org/obo/NCBITaxon_91835 fabids http://purl.obolibrary.org/obo/NCBITaxon_123484 Tripterygium http://purl.obolibrary.org/obo/NCBITaxon_91835 fabids http://purl.obolibrary.org/obo/NCBITaxon_3845 Erythrina variegata http://purl.obolibrary.org/obo/NCBITaxon_91835 fabids http://purl.obolibrary.org/obo/NCBITaxon_54229 Clerodendrum trichotomum http://purl.obolibrary.org/obo/NCBITaxon_91888 lamiids http://purl.obolibrary.org/obo/NCBITaxon_4055 Gentianales http://purl.obolibrary.org/obo/NCBITaxon_91888 lamiids http://purl.obolibrary.org/obo/UBERON_0009615 midbrain hindbrain boundary neural plate http://purl.obolibrary.org/obo/UBERON_0000015 anatomical boundary http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0009856 sac http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0018254 skeletal musculature http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0009911 lobule http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0000153 anterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0000154 posterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0012361 internal anal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0012469 external anal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0011272 embryonic skin basal layer http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium http://purl.obolibrary.org/obo/UBERON_0010375 pancreas dorsal primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0010376 pancreas ventral primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0005795 embryonic uterus http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0009196 indifferent external genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/UBERON_0009708 dorsal pancreas http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0009709 ventral pancreas http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0012139 segment of autopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0009581 midbrain mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0009618 trunk paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0009881 anterior lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/UBERON_0004912 biliary bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0008836 liver bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0015410 heart plus pericardium http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0003076 posterior neural tube http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0003080 anterior neural tube http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0006241 future spinal cord http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0006596 presumptive blood http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0007026 presumptive gut http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0022288 surface of eyeball http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface http://purl.obolibrary.org/obo/UBERON_0009920 optic neural crest http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0010700 phalanx pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015023 phalanx endochondral element http://purl.obolibrary.org/obo/UBERON_0010701 phalanx cartilage element http://purl.obolibrary.org/obo/UBERON_0015064 autopod cartilage http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/CHEBI_26874 terpenol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol http://purl.obolibrary.org/obo/CHEBI_35313 hexoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_50274 secoiridoid glycoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_35312 pentoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_35314 glycosiduronic acid http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_35315 deoxy hexoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_26548 rhamnosylglucoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_38641 trimethylbenzene http://purl.obolibrary.org/obo/CHEBI_38975 methylbenzene http://purl.obolibrary.org/obo/CHEBI_27338 xylene http://purl.obolibrary.org/obo/CHEBI_38975 methylbenzene http://purl.obolibrary.org/obo/CHEBI_12936 D-galactose http://purl.obolibrary.org/obo/CHEBI_28260 galactose http://purl.obolibrary.org/obo/CHEBI_37618 L-galactose http://purl.obolibrary.org/obo/CHEBI_28260 galactose http://purl.obolibrary.org/obo/CHEBI_62754 glycine receptor antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_27081 transition element atom http://purl.obolibrary.org/obo/CHEBI_37253 elemental zinc http://purl.obolibrary.org/obo/CHEBI_27364 zinc molecular entity http://purl.obolibrary.org/obo/CHEBI_47882 cyclic polypyrrole http://purl.obolibrary.org/obo/CHEBI_38077 polypyrrole http://purl.obolibrary.org/obo/CHEBI_35571 mancude organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_35573 organic mancude parent http://purl.obolibrary.org/obo/CHEBI_36388 saturated organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_35552 heterocyclic organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_36895 monoatomic fluorine http://purl.obolibrary.org/obo/CHEBI_36892 elemental fluorine http://purl.obolibrary.org/obo/CHEBI_39131 elemental strontium http://purl.obolibrary.org/obo/CHEBI_37131 strontium molecular entity http://purl.obolibrary.org/obo/NCBITaxon_205465 Tripterygium hypoglaucum http://purl.obolibrary.org/obo/NCBITaxon_123484 Tripterygium http://purl.obolibrary.org/obo/NCBITaxon_458696 Tripterygium wilfordii http://purl.obolibrary.org/obo/NCBITaxon_123484 Tripterygium http://purl.obolibrary.org/obo/NCBITaxon_748693 Clematis chinensis http://purl.obolibrary.org/obo/NCBITaxon_1463138 Ranunculoideae http://purl.obolibrary.org/obo/NCBITaxon_85363 Aconitum carmichaelii http://purl.obolibrary.org/obo/NCBITaxon_1463138 Ranunculoideae http://purl.obolibrary.org/obo/TCMDPO_0000324 微苦（中药） http://purl.obolibrary.org/obo/TCMDPO_0000076 苦（中药） http://purl.obolibrary.org/obo/TCMDPO_0000090 膀胱经 http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/TCMDPO_0000089 肾经 http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/TCMDPO_0000069 胆经 http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/TCMDPO_0000086 胃经 http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/TCMDPO_0000066 肝经 http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/TCMDPO_0000085 脾经 http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/TCMDPO_0000087 心经 http://purl.obolibrary.org/obo/TCMDPO_0000062 药物作用部位 http://purl.obolibrary.org/obo/TCMDPO_0000067 寒（中药） http://purl.obolibrary.org/obo/TCMDPO_0000063 四气（中药） http://purl.obolibrary.org/obo/TCMDPO_0000068 热（中药） http://purl.obolibrary.org/obo/TCMDPO_0000063 四气（中药） http://purl.obolibrary.org/obo/TCMDPO_0000071 温（中药） http://purl.obolibrary.org/obo/TCMDPO_0000063 四气（中药） http://purl.obolibrary.org/obo/TCMDPO_0000072 凉（中药） http://purl.obolibrary.org/obo/TCMDPO_0000063 四气（中药） http://purl.obolibrary.org/obo/TCMDPO_0000075 平（中药） http://purl.obolibrary.org/obo/TCMDPO_0000063 四气（中药） http://purl.obolibrary.org/obo/TCMDPO_0000076 苦（中药） http://purl.obolibrary.org/obo/TCMDPO_0000064 中药五味 http://purl.obolibrary.org/obo/TCMDPO_0000070 酸（中药） http://purl.obolibrary.org/obo/TCMDPO_0000064 中药五味 http://purl.obolibrary.org/obo/TCMDPO_0000077 甘（中药） http://purl.obolibrary.org/obo/TCMDPO_0000064 中药五味 http://purl.obolibrary.org/obo/TCMDPO_0000079 咸（中药） http://purl.obolibrary.org/obo/TCMDPO_0000064 中药五味 http://purl.obolibrary.org/obo/TCMDPO_0000078 辛（中药） http://purl.obolibrary.org/obo/TCMDPO_0000064 中药五味 http://purl.obolibrary.org/obo/TCMDPO_0000080 大毒 http://purl.obolibrary.org/obo/TCMDPO_0000065 毒性 http://purl.obolibrary.org/obo/TCMDPO_0000081 有毒 http://purl.obolibrary.org/obo/TCMDPO_0000065 毒性 http://purl.obolibrary.org/obo/TCMDPO_0000326 大热 http://purl.obolibrary.org/obo/TCMDPO_0000068 热（中药） http://purl.obolibrary.org/obo/TCMDPO_0000325 微温（中药） http://purl.obolibrary.org/obo/TCMDPO_0000071 温（中药） http://purl.obolibrary.org/obo/OAE_0003243 coordination and balance disorder AE coordination and balance disturbance AE a cross product of coordination abnormal AE and balance disorder AE http://purl.obolibrary.org/obo/BFO_0000001 entity http://purl.obolibrary.org/obo/RO_0002087 immediately_preceded_by http://purl.obolibrary.org/obo/BFO_0000062 preceded_by starts_at_end_of X immediately_preceded_by Y iff: end(X) simultaneous_with start(Y) http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/RO_0002507 has material contribution from has_part a core relation that holds between a whole and its part http://purl.obolibrary.org/obo/BFO_0000062 preceded_by http://purl.obolibrary.org/obo/RO_0002086 ends after preceded_by X preceded_by Y iff: end(Y) before_or_simultaneous_with start(X) http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002131 overlaps part_of a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/RO_0002224 starts with http://purl.obolibrary.org/obo/RO_0002222 temporally related to started by x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002230 ends with http://purl.obolibrary.org/obo/RO_0002222 temporally related to finished by x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/OAE_0002081 adverse event occurs in http://purl.obolibrary.org/obo/BFO_0000066 occurs in a 'occurs in' relation that is applied at the adverse event setting and indicates where an adverse event occurs in. http://purl.obolibrary.org/obo/RO_0002178 supplies http://purl.obolibrary.org/obo/RO_0002170 connected to relation between an artery and the structure is supplies with blood. http://purl.obolibrary.org/obo/uberon/core#distally_connected_to distally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. http://purl.obolibrary.org/obo/uberon/core#in_central_side_of in_central_side_of http://purl.obolibrary.org/obo/BFO_0000050 part of X in_central_side Y <=> if Y is subdivided into left and right portions around some median divisor, all parts of X are closer to the median divisor than the outermost lateral sides. http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to proximally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/RO_0002222 temporally related to x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 part of Relation between occurrents, shares a start boundary with. http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/BSPO_0000122 in_posterior_side_of http://purl.obolibrary.org/obo/BFO_0000050 part of X posterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the posterior portion. http://purl.obolibrary.org/obo/BSPO_0000123 in_anterior_side_of http://purl.obolibrary.org/obo/BFO_0000050 part of X anterior_side_of Y <=> if Y is subdivided into two anterior and posterior portions, X is part_of the anterior portion. http://purl.obolibrary.org/obo/BSPO_0000124 in_proximal_side_of http://purl.obolibrary.org/obo/BFO_0000050 part of X proximal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the proximal portion. http://purl.obolibrary.org/obo/BSPO_0000125 in_distal_side_of http://purl.obolibrary.org/obo/BFO_0000050 part of X distal_side_of Y <=> if Y is subdivided into distal and proximal portions, X is part_of the distal portion. http://purl.obolibrary.org/obo/BSPO_0000126 in_lateral_side_of http://purl.obolibrary.org/obo/BFO_0000050 part of X in_lateral_side_of Y <=> if X is in_left_side_of Y or X is in_right_side_of Y. X is often, but not always a paired structure http://purl.obolibrary.org/obo/BSPO_0001106 proximalmost_part_of http://purl.obolibrary.org/obo/BSPO_0000124 in_proximal_side_of X proximalmost_part_of Y <=> X is part_of Y and X is adjacent_to the proximal boundary of Y http://purl.obolibrary.org/obo/BSPO_0001108 distalmost_part_of http://purl.obolibrary.org/obo/BSPO_0000125 in_distal_side_of X distalmost_part_of Y <=> X is part_of Y and X is adjacent_to the distal boundary of Y http://purl.obolibrary.org/obo/RO_0002473 composed primarily of http://purl.obolibrary.org/obo/BFO_0000051 has part x composed_primarily_of y iff: more than half of the mass of x is made from parts of y http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to transitively_connected to Binary relationship: x connected_to y if and only if there exists some z such that z connects x and y in a ternary connected_to(x,y,z) relationship. http://purl.obolibrary.org/obo/RO_0002488 existence starts during http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after Relation between continuant c and occurrent s, such that every instance of c comes into existing during some s. http://purl.obolibrary.org/obo/RO_0002489 existence starts with http://purl.obolibrary.org/obo/RO_0002488 existence starts during Relation between continuant and occurrent, such that c comes into existence at the start of p. http://purl.obolibrary.org/obo/RO_0002492 existence ends during http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before Relation between continuant c and occurrent s, such that every instance of c ceases to exist during some s, if it does not die prematurely. http://purl.obolibrary.org/obo/RO_0002493 existence ends with http://purl.obolibrary.org/obo/RO_0002492 existence ends during Relation between continuant and occurrent, such that c ceases to exist at the end of p. http://purl.obolibrary.org/obo/RO_0002551 has skeleton http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between a subdivision of an organism and the single subdivision of skeleton that provides structural support for that subdivision. http://purl.obolibrary.org/obo/RO_0002082 simultaneous_with http://purl.obolibrary.org/obo/RO_0002229 ends Relation between occurrents, shares start and end boundaries. http://purl.obolibrary.org/obo/RO_0002229 ends http://purl.obolibrary.org/obo/BFO_0000050 part of Relation between occurrents, shares an end boundary with. http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with http://purl.obolibrary.org/obo/RO_0002222 temporally related to <= http://purl.obolibrary.org/obo/RO_0002090 immediately precedes http://purl.obolibrary.org/obo/BFO_0000063 precedes meets http://purl.obolibrary.org/obo/RO_0002091 starts during http://purl.obolibrary.org/obo/RO_0002222 temporally related to io http://purl.obolibrary.org/obo/RO_0002092 happens during http://purl.obolibrary.org/obo/RO_0002093 ends during during http://purl.obolibrary.org/obo/RO_0002093 ends during http://purl.obolibrary.org/obo/RO_0002222 temporally related to overlaps http://purl.obolibrary.org/obo/RO_0002494 transformation of http://purl.obolibrary.org/obo/RO_0002202 develops_from http://purl.obolibrary.org/obo/RO_0002351 has member http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/RO_0002371 attaches_to http://purl.obolibrary.org/obo/RO_0002177 attaches_to_part_of http://purl.obolibrary.org/obo/RO_0002202 develops_from http://purl.obolibrary.org/obo/RO_0002507 has material contribution from http://purl.obolibrary.org/obo/RO_0002086 ends after http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002007 bounding layer of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002572 luminal space of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002576 skeleton of http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002203 develops_into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/uberon/core#existence_starts_and_ends_during existence starts and ends during http://purl.obolibrary.org/obo/RO_0002492 existence ends during http://purl.obolibrary.org/obo/RO_0002495 immediate transformation of http://purl.obolibrary.org/obo/RO_0002494 transformation of http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from http://purl.obolibrary.org/obo/RO_0002507 has material contribution from http://purl.obolibrary.org/obo/uberon/core#evolved_from evolved_from http://purl.obolibrary.org/obo/RO_0002158 homologous_to http://purl.obolibrary.org/obo/RO_0000052 inheres in inheres_in a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000056 participates in participates_in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000057 has participant has_participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/BFO_0000066 occurs in unfolds_in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/OAE_0001788 has participant quality an object property that represents a relation between a process and a quality, in which the process has a participant that has the quality. http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to transitively distally connected to . http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to transitively proximally connected to . http://purl.obolibrary.org/obo/BFO_0000067 contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0002219 surrounded_by x surrounded_by y iff: x is adjacent to y and for every region r adjacent to x, r overlaps y http://purl.obolibrary.org/obo/RO_0002220 adjacent_to x adjacent_to y iff: x and y share a boundary http://purl.obolibrary.org/obo/RO_0002176 connects Binary relationship: z connects x if and only if there exists some y such that z connects x and y in a ternary connected_to(x,y,z) relationship. http://purl.obolibrary.org/obo/BSPO_0000096 anterior_to x anterior_to y iff x is further along the antero-posterior axis than y, towards the head. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail: bearer http://purl.obolibrary.org/obo/BSPO_0000097 distal_to x distal_to y iff x is further along the proximo-distal axis than y, towards the appendage tip. A proximo-distal axis extends from tip of an appendage (distal) to where it joins the body (proximal). http://purl.obolibrary.org/obo/BSPO_0000098 dorsal_to x dorsal_to y iff x is further along the dorso-ventral axis than y, towards the back. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly). http://purl.obolibrary.org/obo/BSPO_0000099 posterior_to x posterior_to y iff x is further along the antero-posterior axis than y, towards the body/tail. An antero-posterior axis is an axis that bisects an organism from head end to opposite end of body or tail. http://purl.obolibrary.org/obo/BSPO_0000100 proximal_to x proximal_to y iff x is closer to the point of attachment with the body than y. http://purl.obolibrary.org/obo/BSPO_0000102 ventral_to x ventral_to y iff x is further along the dorso-ventral axis than y, towards the front. A dorso-ventral axis is an axis that bisects an organism from back (e.g. spinal column) to front (e.g. belly). http://purl.obolibrary.org/obo/BSPO_0000107 deep_to Further away from the surface of the organism. Thus, the muscular layer is deep to the skin, but superficial to the intestines. http://purl.obolibrary.org/obo/BSPO_0000108 superficial_to Near the outer surface of the organism. Thus, skin is superficial to the muscle layer. http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A mereological relationship or a topological relationship http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into x has the potential to develop into y iff x develops into y or if x is capable of developing into y http://purl.obolibrary.org/obo/uberon/core#conduit_for conduit for x is a conduit for y iff y passes through the lumen of x. http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y http://purl.obolibrary.org/obo/RO_0002221 surrounds inverse of surrounded_by http://purl.obolibrary.org/obo/RO_0002256 developmentally_induced_by t1 developmentally_induced_by t2 if there is a process of organ induction (GO:0001759) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor tissue type T to T', where T' develops_from T. http://purl.obolibrary.org/obo/BFO_0000054 realized in realized_in http://purl.obolibrary.org/obo/BFO_0000053 is_bearer_of bearer_of http://purl.obolibrary.org/obo/OAE_0001735 is evidence of http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by http://purl.obolibrary.org/obo/uberon/core#channels_from channels_from http://purl.obolibrary.org/obo/uberon/core#channels_into channels_into http://purl.obolibrary.org/obo/RO_0001015 location_of http://purl.obolibrary.org/obo/RO_0002002 has boundary http://purl.obolibrary.org/obo/RO_0001025 located_in http://purl.obolibrary.org/obo/RO_0003000 produces http://purl.obolibrary.org/obo/RO_0003001 produced_by http://purl.obolibrary.org/obo/chebi#has_functional_parent has functional parent http://purl.obolibrary.org/obo/chebi#has_parent_hydride has parent hydride http://purl.obolibrary.org/obo/chebi#is_conjugate_acid_of is conjugate acid of http://purl.obolibrary.org/obo/chebi#is_conjugate_base_of is conjugate base of http://purl.obolibrary.org/obo/chebi#is_enantiomer_of is enantiomer of http://purl.obolibrary.org/obo/chebi#is_substituent_group_from is substituent group from http://purl.obolibrary.org/obo/chebi#is_tautomer_of is tautomer of http://purl.obolibrary.org/obo/RO_0000087 has role http://purl.obolibrary.org/obo/chebi#BFO_0000051 has part http://purl.obolibrary.org/obo/RO_0002150 continuous_with http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002177 attaches_to_part_of http://purl.obolibrary.org/obo/RO_0002433 contributes to morphology of http://purl.obolibrary.org/obo/RO_0002507 has material contribution from http://purl.obolibrary.org/obo/uberon/core#channel_for channel for http://purl.obolibrary.org/obo/uberon/core#protects protects http://purl.obolibrary.org/obo/uberon/core#subdivision_of subdivision of http://purl.obolibrary.org/obo/uberon/core#transitively_connected_to transitively_connected to http://www.obofoundry.org/ro/ro.owl#has_proper_part has_proper_part http://purl.obolibrary.org/obo/TCMDPO_0000321 具有...药性 http://purl.obolibrary.org/obo/RO_0002158 homologous_to http://purl.obolibrary.org/obo/RO_0002285 developmentally_replaces http://purl.obolibrary.org/obo/TCMDPO_0000320 归...经 http://purl.obolibrary.org/obo/TCMDPO_0000322 具有...药味 http://purl.obolibrary.org/obo/TCMDPO_0000323 具有...毒性