Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/OGI_0000027 sequence tagged site http://purl.obolibrary.org/obo/OGI_0000020 genomic site STS any unique piece of DNA for which a specific PCR assay has been designed, so that any DNA sample can be easily tested for its presence or absense. http://purl.obolibrary.org/obo/OGI_0000082 genotype http://purl.obolibrary.org/obo/OGI_0000019 genetic interval aggregate genotype diploid collective of allele which comes from different homologus chromosomes respecitvely. http://purl.obolibrary.org/obo/OGI_0000085 SNP interval http://purl.obolibrary.org/obo/OGI_0000002 genetic interval single nucleotide polymorphism interval a genetic interval that bears the SNP quality and has only one nucleotide residue http://purl.obolibrary.org/obo/OAE_0000361 fever AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event pyrexia AE an abnormal body temperature AE which has an outcome of fever http://purl.obolibrary.org/obo/OAE_0000429 Guillain-Barre syndrome AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event GBS AE a nervous system AE that has the symptom of GBS. Guillain-Barre syndrome (GBS) is a disorder in which the body's immune system attacks part of the peripheral nervous system. The first symptoms of this disorder include varying degrees of weakness or tingling sensations in the legs. In many instances, the weakness and abnormal sensations spread to the arms and upper body. These symptoms can increase in intensity until the muscles cannot be used at all and the patient is almost totally paralyzed. In these cases, the disorder is life-threatening and is considered a medical emergency. Usually Guillain-Barre occurs a few days or weeks after the patient has had symptoms of a respiratory or gastrointestinal viral infection. Occasionally, surgery or vaccinations will trigger the syndrome. Reference: http://www.ninds.nih.gov/disorders/gbs/gbs.htm. http://purl.obolibrary.org/obo/OAE_0000481 multiple sclerosis AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event encephalomyelitis disseminata multiple sclerosis AE is an immune system disorder AE, or an autoimmune condition in which the immune system attacks the central nervous system, leading to demyelination. http://purl.obolibrary.org/obo/VO_0000642 Influenza virus vaccine http://purl.obolibrary.org/obo/VO_0000609 viral vaccine Influenza vaccine A viral vaccine that protects against infection with influenza virus. http://purl.obolibrary.org/obo/OGSF_0000000 genetic susceptibility http://purl.obolibrary.org/obo/BFO_0000016 disposition genetic predisposition a disposition that is physically based on some genetic material, such as one or more gene mutations or variant, such that if the genome of an organism has the genetic material as its part, the organism may have an increased likelihood or chance to develop: 1) a particular disease; 2) a peculiar biological/bodily process. http://purl.obolibrary.org/obo/PATO_0000719 viable http://purl.obolibrary.org/obo/PATO_0000169 viability live A viability quality inhering in a bearer or a population by virtue of the bearer's ability to survive and develop normally or the long term survival ability of a given population. http://purl.obolibrary.org/obo/OGI_0000075 radiation hybrid map http://purl.obolibrary.org/obo/OGI_0000074 genetics map RH map A map based on the co-occurrence of markers in a panel of radiation hybrid cell lines, resulting in an ordering of markers along a chromosome backbone. http://purl.obolibrary.org/obo/BFO_0000002 continuant http://purl.obolibrary.org/obo/BFO_0000001 entity endurant An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant substantial entity A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant trope A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/IAO_0000030 information content entity data a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements. http://purl.obolibrary.org/obo/IAO_0000300 textual entity http://purl.obolibrary.org/obo/IAO_0000030 information content entity text A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc. http://purl.obolibrary.org/obo/IAO_0000312 publication about an investigation http://purl.obolibrary.org/obo/IAO_0000311 publication scientific publication A publication that is about an investigation http://purl.obolibrary.org/obo/OBI_0000066 investigation http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s). http://purl.obolibrary.org/obo/OBI_0000174 study group role http://purl.obolibrary.org/obo/BFO_0000023 role study group population a study population role where the bearer is a population of material entities and the role is realized in the implementation of a study design wherein the entities bearing the study population role are observed or subjected to intervention according to the study design and are biological replicates, i.e. they receive the same treatment under the protocol http://purl.obolibrary.org/obo/OBI_0200000 data transformation http://purl.obolibrary.org/obo/OBI_0000011 planned process data processing A data transformation is a process which produces output data from input data http://purl.obolibrary.org/obo/SO_0000001 region http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant sequence A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids. http://purl.obolibrary.org/obo/VO_0000002 vaccination http://purl.obolibrary.org/obo/OBI_0600007 administering substance in vivo vaccine administration a process of administering substance in vivo that involves in adding a vaccine into a host (e.g., human) in vivo with the intent to invoke a protective or therapeutic adaptive immune response. http://purl.obolibrary.org/obo/VO_0001375 organism vaccinated with a licensed vaccine http://purl.obolibrary.org/obo/VO_0001374 vaccinated organism vaccinee a vaccinated organism that is vaccinated with a licensed vaccine http://purl.obolibrary.org/obo/OGI_0000002 genetic interval http://purl.obolibrary.org/obo/OGI_0000001 biological material interval genomic material interval the spatial continuous physical entity which contains ordered genomic sets(DNA, RNA, Allele, Marker,etc.) between and including two points(Nucleic_Acid_Base_Residue) on a chromosome or RNA molecule which must have a liner primary sequence sturcture. http://purl.obolibrary.org/obo/OAE_0000001 adverse event http://purl.obolibrary.org/obo/OGMS_0000061 pathological bodily process adverse reaction a pathological bodily process that occurs after a medical intervention. http://purl.obolibrary.org/obo/VO_0000410 Pandemrix http://purl.obolibrary.org/obo/VO_0000642 Influenza virus vaccine Pandemrix H1N1 Pandemrix is an influenza vaccine for influenza pandemics, such as the H1N1 2009 flu pandemic colloquially called the swine flu. The vaccine was developed by GlaxoSmithKline and patented in September 2006. http://purl.obolibrary.org/obo/VO_0000771 BCG vaccine http://purl.obolibrary.org/obo/VO_0000001 vaccine Bacillus Calmette Guerin BCG Vaccine is a Mycobacterium tuberculosis vaccine that is a live attenuated strain of Mycobacterium bovis (Bacillus Calmette Guerin; BCG). http://purl.obolibrary.org/obo/SO_0001023 SO:allele http://purl.obolibrary.org/obo/SO_0001411 biological_region SO:allele An allele is one of a set of coexisting sequence variants of a gene. http://purl.obolibrary.org/obo/REO_0000826 genetic material http://purl.obolibrary.org/obo/BFO_0000040 material entity genomic nucleic acid A nucleic acid macromolecule or submolecule that is part of a cell or virion and has been inherited from an ancestor cell or virion, and/or can be replicated and inherited by its progeny. http://purl.obolibrary.org/obo/SO_0001411 biological_region http://purl.obolibrary.org/obo/SO_0000001 region biological region A region defined by its disposition to be involved in a biological process. http://purl.obolibrary.org/obo/SO_0000704 SO:gene http://purl.obolibrary.org/obo/SO_0001411 biological_region SO:gene A region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions. http://purl.obolibrary.org/obo/ERO_0000019 genome wide association study http://purl.obolibrary.org/obo/OGSF_0000017 case control genetic association study GWAS A genome wide association study is an examination of genetic variation across a given genome, designed to identify genetic associations with observable traits. http://purl.obolibrary.org/obo/VO_0000494 vaccine immunization http://purl.obolibrary.org/obo/VO_0000491 active immunization artificial active immunization artificial active immunization is an active immunization that occurs when a person or animal is vaccinated with a specific vaccine. http://purl.obolibrary.org/obo/VO_0000590 vaccine preparation http://purl.obolibrary.org/obo/OBI_0000011 planned process vaccine production vaccine preparation is a manufacturing process to produce a vaccine. http://purl.obolibrary.org/obo/VO_0000179 vaccine component http://purl.obolibrary.org/obo/BFO_0000040 material entity cardinal part of vaccine a processed material that is output of the vaccine preparation and part of a vaccine. http://purl.obolibrary.org/obo/VO_0000452 preventive vaccine function http://purl.obolibrary.org/obo/VO_0000278 vaccine function prophylactic vaccine function preventive vaccine function is a vaccine function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which protects against a specific disorder. http://purl.obolibrary.org/obo/OGI_0000033 alternative allele of SNP http://purl.obolibrary.org/obo/OGI_0000062 allele of SNP allele of SNP that designated by smaller allele frequency in a population than a more common allele's frequency. http://purl.obolibrary.org/obo/OGI_0000008 allele http://purl.obolibrary.org/obo/OGI_0000006 DNA segment Mutually exclusive alternative forms of the same genetic interval occupying the same locus on homologous chromosomes, differing in DNA sequence and governing the same biochemical and developmental process. http://purl.obolibrary.org/obo/OGI.owl#Author author http://purl.obolibrary.org/obo/BFO_0000040 material entity a human being that bears an author role. http://purl.obolibrary.org/obo/OGI.owl#Enhancer enhancer http://purl.obolibrary.org/obo/OGI_0000042 gene regulatory element a set of short sequence elements which stimulate transcription of a gene and whose function is not critically dependent on their precise position or orientation. http://purl.obolibrary.org/obo/OGI.owl#Promoter promoter http://purl.obolibrary.org/obo/OGI_0000042 gene regulatory element a combination of short sequence elements, normally just upstream of a gene, to which RNA polymerase binds in order to initiate transcription of the gene. http://purl.obolibrary.org/obo/OGI_0000010 protein interval http://purl.obolibrary.org/obo/OGI_0000001 biological material interval The biological material interval that is a protein, which is made of amino acid chain. http://purl.obolibrary.org/obo/OGI_0000012 genetic variation http://purl.obolibrary.org/obo/BFO_0000019 quality Genetic variationis a variation in alleles of genes, occurs both within and among populations. http://purl.obolibrary.org/obo/OGI_0000022 locus http://purl.obolibrary.org/obo/OGI_0000020 genomic site a unique chromosomal location defining the position of an individual gene or DNA sequence. http://purl.obolibrary.org/obo/OGI_0000035 allele of gene http://purl.obolibrary.org/obo/OGI_0000008 allele allele that is a set of alternative forms of the same gene occupying the same gene locus. http://purl.obolibrary.org/obo/OGI_0000037 allele of polymorphism http://purl.obolibrary.org/obo/OGI_0000008 allele allele that is set of alternative form of the polymorphic region that occupy the same locus on chromosomes. http://purl.obolibrary.org/obo/OGI_0000051 genetic marker http://purl.obolibrary.org/obo/OGI_0000003 DNA interval A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. It can be described as a variation (which may arise due to mutation or alteration in the genomic loci) that can be observed. A genetic marker may be a short DNA sequence, such as a sequence surrounding a single base-pair change (single nucleotide polymorphism, SNP), or a long one, like minisatellites. http://purl.obolibrary.org/obo/OGI_0000062 allele of SNP http://purl.obolibrary.org/obo/OGI_0000037 allele of polymorphism The two alternative forms of SNP that occupying the same SNP site on the chromosome. http://purl.obolibrary.org/obo/OGI_0000064 probe http://purl.obolibrary.org/obo/OGI_0000003 DNA interval a fragment of DNA of variable length (usually 100-1000 bases long), which is used to detect in DNA or RNA samples the presence of nucleotide sequences (the DNA target) that are complementary to the sequence in the probe. http://purl.obolibrary.org/obo/OGI_0000077 genetic physical map http://purl.obolibrary.org/obo/OGI_0000074 genetics map An ordered set of genomic DNA clones demarcated with restriction endonuclease recognition or sequence tagged sites. The distance between sites is mesured in base pair. http://purl.obolibrary.org/obo/OGI_0000083 mitochondiral genome http://purl.obolibrary.org/obo/SO_0001026 genome genome that is located in mitochondria. http://purl.obolibrary.org/obo/OGI_0000086 chromosome abnormality http://purl.obolibrary.org/obo/OGI_0000012 genetic variation A chromosome anomaly, abnormality or aberration reflects an atypical number of chromosomes or a structural abnormality in one or more chromosomes. http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGI_0000012 genetic variation strictly, the existense of two or more variants(alleles, phenotypes, sequence variants, chromosomal structural variants) at significant frequencies (i.e. more than 1%) in the population. http://purl.obolibrary.org/obo/OGI_0000104 minor allele frequency http://purl.obolibrary.org/obo/IAO_0000027 data item is the ratio of chromosomes in the population carrying the less common variant to those with the more common variant. http://purl.obolibrary.org/obo/OGSF_0000001 genetic susceptibility to pathological bodily process http://purl.obolibrary.org/obo/OGSF_0000000 genetic susceptibility a genetic susceptibility that lead to the increased possibilities to initiate a patholoical bodily process in the organism, whose genome has related genetic susceptibility factor (he physical basis of this genetic susceptibility) as its part. http://purl.obolibrary.org/obo/OGSF_0000002 genetic susceptibility to biological process http://purl.obolibrary.org/obo/OGSF_0000000 genetic susceptibility a genetic susceptibility that lead to the increased possibilities to initiate a biological process in an organism, whose genome has related genetic susceptibility factor (he physical basis of this genetic susceptibility) as its part. http://purl.obolibrary.org/obo/OGSF_0000003 genetic susceptibility to adverse event http://purl.obolibrary.org/obo/OGSF_0000001 genetic susceptibility to pathological bodily process a genetic susceptibility that lead to the increased possibilities to initiate adverse event in an organism, whose genome has related genetic susceptibility factor (he physical basis of this genetic susceptibility) as its part. http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor http://purl.obolibrary.org/obo/BFO_0000040 material entity a genetic material that is the material base of genetic susceptibility http://purl.obolibrary.org/obo/OGSF_0000005 susceptibility gene http://purl.obolibrary.org/obo/OGI_0000004 gene genetic susceptibility factor that is a gene http://purl.obolibrary.org/obo/OGSF_0000006 susceptibility haplotype http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor genetic susceptibility factor that is a haplotype http://purl.obolibrary.org/obo/OGSF_0000007 susceptibility allele of SNP http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor genetic susceptibility factor that is a Simple Nucleotide Polymorphism (SNP). http://purl.obolibrary.org/obo/OGSF_0000008 susceptibility genotype http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor genetic susceptibility factor that is a genotype http://purl.obolibrary.org/obo/OGSF_0000009 susceptibility allele http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor genetic susceptibility factor that is an allele http://purl.obolibrary.org/obo/OGSF_0000015 genetic susceptibility to drug adverse event http://purl.obolibrary.org/obo/OGSF_0000003 genetic susceptibility to adverse event a genetic susceptibility to adverse event that is proceded by a drug administration http://purl.obolibrary.org/obo/OGSF_0000018 initial GWAS study http://purl.obolibrary.org/obo/ERO_0000019 genome wide association study The first Genome Wide Association Study that conducted in a population to observe the genetic association with a phenotype or trait. http://purl.obolibrary.org/obo/OGSF_0000019 replicate GWAS study http://purl.obolibrary.org/obo/ERO_0000019 genome wide association study the GWAS study that intend to repeat initial GWAS study's observation over a different population using a different design and methods by different investigation teams. http://purl.obolibrary.org/obo/OGSF_0000031 positive conclusion of genetic susceptibility http://purl.obolibrary.org/obo/OGSF_0000012 textual conclusion of genetic susceptibility The textual conclusion from the paper that mentioned the genetic susceptibility of the genetic susceptibility factors that is statistically meaningful (statistically supported). http://purl.obolibrary.org/obo/OGSF_0000033 neutral conclusion of genetic susceptibility http://purl.obolibrary.org/obo/OGSF_0000012 textual conclusion of genetic susceptibility The textual conclusion from the paper that mentioned the genetic susceptibility of a genetic susceptibility factors is neither deny nor support by statistical calculation. http://purl.obolibrary.org/obo/OGSF_0001039 genetic susceptibility to adverse event following Pandemix vaccination http://purl.obolibrary.org/obo/OGSF_0000010 genetic susceptibility to vaccine adverse event a genetic susceptibility to adverse event that is proceded by a vaccination process. http://purl.obolibrary.org/obo/OGSF_0001040 genetic susceptibility to multiple scelorosis AE following Pandemix vaccination http://purl.obolibrary.org/obo/OGSF_0001039 genetic susceptibility to adverse event following Pandemix vaccination a genetic susceptibility to adverse event that is proceded by a vaccination process. http://purl.obolibrary.org/obo/CHEBI_33708 amino-acid residue http://purl.obolibrary.org/obo/OGI_0000009 genetic interval base residue When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue. http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. http://purl.obolibrary.org/obo/OAE_0000004 vaccine adverse event http://purl.obolibrary.org/obo/OAE_0000001 adverse event an adverse event that is induced by vaccination. http://purl.obolibrary.org/obo/OAE_0000053 wheezing AE http://purl.obolibrary.org/obo/OAE_0000001 adverse event a respiratory system AE which has an outcome of wheezing http://purl.obolibrary.org/obo/OAE_0000063 systematic adverse event http://purl.obolibrary.org/obo/OAE_0000001 adverse event an adverse event that occurs systematically in a patient's body. http://purl.obolibrary.org/obo/VO_0000609 viral vaccine http://purl.obolibrary.org/obo/VO_0000001 vaccine A vaccine that protects against some viral disease. http://purl.obolibrary.org/obo/PATO_0000169 viability http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity An organismal quality inhering in a bearer or a population by virtue of the bearer's ability or inability to survive and develop normally or the number of surviving individuals in a given population. http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/BFO_0000019 quality A quality which inheres in a continuant. http://purl.obolibrary.org/obo/PATO_0002146 virulence http://purl.obolibrary.org/obo/PATO_0001995 organismal quality A quality inhering in a bearer by virtue of the bearer's pathogenicity. http://purl.obolibrary.org/obo/OGSF_0000017 case control genetic association study http://purl.obolibrary.org/obo/OGSF_0000016 genetic association investigation Genetic association investigation that use to observe the non-random differences of a genetic factor's frequency between case group and control group. http://purl.obolibrary.org/obo/OGI_0000076 linkage map http://purl.obolibrary.org/obo/OGI_0000074 genetics map A map based upon frequency of recombination between genomic segments, resulting in the ordering of markers along a chromosome backbone, usually measured in centiMorgans (cM). http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. http://purl.obolibrary.org/obo/BFO_0000035 process boundary http://purl.obolibrary.org/obo/BFO_0000003 occurrent p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. http://purl.obolibrary.org/obo/IAO_0000005 objective specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved. http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant an information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity http://purl.obolibrary.org/obo/IAO_0000033 directive information entity http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity whose concretizations indicate to their bearer how to realize them in a process. http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data item data about an ontology part is a data item about a part of an ontology, for example a term http://purl.obolibrary.org/obo/IAO_0000144 conclusion textual entity http://purl.obolibrary.org/obo/IAO_0000300 textual entity A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers. http://purl.obolibrary.org/obo/IAO_0000310 document http://purl.obolibrary.org/obo/IAO_0000030 information content entity A collection of information content entities intended to be understood together as a whole http://purl.obolibrary.org/obo/IAO_0000311 publication http://purl.obolibrary.org/obo/IAO_0000310 document A document that has been accepted by a publisher http://purl.obolibrary.org/obo/IAO_0000442 author role http://purl.obolibrary.org/obo/BFO_0000023 role A role inhering in a person or organization that is realized when the bearer participates in the work which is the basis of the document, in the writing of the document, and signs it with their name. http://purl.obolibrary.org/obo/OBI_0000011 planned process http://purl.obolibrary.org/obo/BFO_0000015 process A processual entity that realizes a plan which is the concretization of a plan specification. http://purl.obolibrary.org/obo/OBI_0000016 regulation-assigned role http://purl.obolibrary.org/obo/OBI_0000017 regulatory role Regulation-assigned role is a regulatory role defined by legislation or governmental orders http://purl.obolibrary.org/obo/OBI_0000017 regulatory role http://purl.obolibrary.org/obo/BFO_0000023 role a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body. http://purl.obolibrary.org/obo/OBI_0000047 processed material http://purl.obolibrary.org/obo/BFO_0000040 material entity Is a material entity that is created or changed during material processing. http://purl.obolibrary.org/obo/OBI_0000097 study subject role http://purl.obolibrary.org/obo/BFO_0000023 role study subject role inheres in an entity and realized through the execution of a study design in which the entity participates by being that which the results are about. http://purl.obolibrary.org/obo/OBI_0000175 p-value http://purl.obolibrary.org/obo/IAO_0000027 data item A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone. http://purl.obolibrary.org/obo/OBI_0000181 population http://purl.obolibrary.org/obo/BFO_0000040 material entity a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area http://purl.obolibrary.org/obo/OBI_0000245 organization http://purl.obolibrary.org/obo/BFO_0000040 material entity An organization is a continuant entity which can play roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. http://purl.obolibrary.org/obo/OBI_0000319 material to be added role http://purl.obolibrary.org/obo/BFO_0000023 role material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process http://purl.obolibrary.org/obo/OBI_0000444 target of material addition role http://purl.obolibrary.org/obo/BFO_0000023 role target of material addition role is a role realized by an entity into which a material is added in a material addition process http://purl.obolibrary.org/obo/OBI_0000725 host role http://purl.obolibrary.org/obo/BFO_0000023 role host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role http://purl.obolibrary.org/obo/OBI_0000811 primary structure of DNA macromolecule http://purl.obolibrary.org/obo/OGI_0000013 primary structure of biological interval a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues. http://purl.obolibrary.org/obo/OBI_0000845 primary structure of RNA molecule http://purl.obolibrary.org/obo/OGI_0000013 primary structure of biological interval The primary structure of an RNA molecule that is completely defined by the set of its nucleic residue parts and the linear order induced by the peptide bonds that hold them together http://purl.obolibrary.org/obo/OBI_0000896 secondary structure of RNA molecule http://purl.obolibrary.org/obo/OBI_0000885 secondary structure of sequence macromolecule http://purl.obolibrary.org/obo/OBI_0001225 genetic population background information http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information a genetic characteristics information which is a part of genotype information that identifies the population of organisms http://purl.obolibrary.org/obo/OBI_0001294 wild type organism genotype information http://purl.obolibrary.org/obo/OBI_0001305 genotype information a genotype information about an organism and includes information that there are no known modifications to the genetic background. Generally it is the genotype information of a representative individual from a class of organisms. http://purl.obolibrary.org/obo/OBI_0001305 genotype information http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc. http://purl.obolibrary.org/obo/OBI_0001352 allele information http://purl.obolibrary.org/obo/OBI_0001364 genetic alteration information a genetic alteration information that about one of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on sequence. Polymorphisms are included in this definition. http://purl.obolibrary.org/obo/OBI_0001364 genetic alteration information http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc. http://purl.obolibrary.org/obo/OBI_0001369 wild type allele information http://purl.obolibrary.org/obo/OBI_0001352 allele information an allele information that is about the allele found most frequently in natural populations, or in standard laboratory stocks for a given organism. http://purl.obolibrary.org/obo/OBI_0001404 genetic characteristics information http://purl.obolibrary.org/obo/IAO_0000027 data item a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes. http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. http://purl.obolibrary.org/obo/OBI_0600007 administering substance in vivo http://purl.obolibrary.org/obo/OBI_0000011 planned process A process by which a substance is intentionally given to an organism http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A physical object quality which inheres in a single-bearer. http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity A quality that inheres in an entire organism or part of an organism. http://purl.obolibrary.org/obo/VO_0000001 vaccine http://purl.obolibrary.org/obo/OBI_0000047 processed material A vaccine is a processed material with the function that when administered, it prevents or ameliorates a disorder in a target organism by inducing or modifying adaptive immune responses specific to the antigens in the vaccine. http://purl.obolibrary.org/obo/OGSF_0000010 genetic susceptibility to vaccine adverse event http://purl.obolibrary.org/obo/OGSF_0000003 genetic susceptibility to adverse event a genetic susceptibility to adverse event that is proceded by a vaccination process. http://purl.obolibrary.org/obo/CHEBI_16842 formaldehyde http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity The simplest aldehyde. http://purl.obolibrary.org/obo/OGI_0000001 biological material interval http://purl.obolibrary.org/obo/BFO_0000040 material entity the spatial continuous physical entity which contains ordered biological sets (DNA segments, Genetic Markers, Nucleic Acid Base Residues, RNA segments, Protein segments) between two boundaries: start boundary and end boundary on a chromosome, RNA or protein. http://purl.obolibrary.org/obo/GO_0005575 cellular_component http://purl.obolibrary.org/obo/BFO_0000040 material entity The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together. http://purl.obolibrary.org/obo/OGMS_0000061 pathological bodily process http://purl.obolibrary.org/obo/BFO_0000015 process A bodily process that is clinically abnormal. http://purl.obolibrary.org/obo/VO_0000137 adjuvant role http://purl.obolibrary.org/obo/BFO_0000023 role A role that inheres in a material entity that helps or enhances the effect of other agents, such as a drug or vaccine. http://purl.obolibrary.org/obo/VO_0000363 licensed vaccine http://purl.obolibrary.org/obo/VO_0000001 vaccine A vaccine that is licensed for commercial use. http://purl.obolibrary.org/obo/VO_0000576 thimerosal vaccine preservative http://purl.obolibrary.org/obo/VO_0000851 vaccine preservative vaccine preservative that has thimerosal as part. http://purl.obolibrary.org/obo/VO_0001346 formaldehyde vaccine preservative http://purl.obolibrary.org/obo/VO_0000851 vaccine preservative a vaccine preservative that contains formaldehyde. http://purl.obolibrary.org/obo/VO_0003036 sucrose vaccine stabilizer http://purl.obolibrary.org/obo/VO_0003034 sugar vaccine stabilizer a vaccine stabilizer that is specifically made by a sucrose. http://purl.obolibrary.org/obo/CHEBI_9546 thimerosal http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity An organomercury compound (approximately 49% mercury by weight) used as an antiseptic and antifungal agent. http://purl.obolibrary.org/obo/VO_0000884 aluminum vaccine adjuvant http://purl.obolibrary.org/obo/VO_0000093 mineral salt vaccine adjuvant a mineral salt vaccine adjuvant that is composed of aluminum salt. http://purl.obolibrary.org/obo/OGMS_0000033 genetic predisposition to disease of type X http://purl.obolibrary.org/obo/OGSF_0000000 genetic susceptibility A predisposition to disease of type X whose physical basis is a constitutional abnormality in an organism's genome. This abnormality is the physical basis for the increased risk of acquiring the disease X. http://purl.obolibrary.org/obo/OGI_0000014 biological sequence http://purl.obolibrary.org/obo/BFO_0000040 material entity the liner sequence of simple repeating units composes DNA molecule, RNA molecule or Protein. http://purl.obolibrary.org/obo/GO_0005634 nucleus http://purl.obolibrary.org/obo/GO_0043226 organelle A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. http://purl.obolibrary.org/obo/GO_0005694 chromosome http://purl.obolibrary.org/obo/GO_0043226 organelle A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. http://purl.obolibrary.org/obo/GO_0005739 mitochondrion http://purl.obolibrary.org/obo/GO_0043226 organelle A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. http://purl.obolibrary.org/obo/GO_0006260 DNA replication http://purl.obolibrary.org/obo/GO_0008150 biological_process The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA. http://purl.obolibrary.org/obo/GO_0006351 transcription, DNA-dependent http://purl.obolibrary.org/obo/GO_0008150 biological_process The cellular synthesis of RNA on a template of DNA. http://purl.obolibrary.org/obo/GO_0006412 translation http://purl.obolibrary.org/obo/GO_0008150 biological_process The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome. http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/BFO_0000015 process Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end. http://purl.obolibrary.org/obo/GO_0010467 gene expression http://purl.obolibrary.org/obo/GO_0008150 biological_process The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0043226 organelle http://purl.obolibrary.org/obo/GO_0005575 cellular_component Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. http://purl.obolibrary.org/obo/OGSF_0000032 negative conclusion of genetic susceptibility http://purl.obolibrary.org/obo/OGSF_0000012 textual conclusion of genetic susceptibility The textual conclusion from the paper that mentioned the genetic susceptibility of a genetic susceptibility factors that is denied by statistical calculation. http://purl.obolibrary.org/obo/ERO_0000016 clinical trial http://purl.obolibrary.org/obo/OBI_0000066 investigation An interventional study that contains a set of procedures in medical research and drug development that are conducted to allow safety (or more specifically, information about adverse drug reactions and adverse effects of other treatments) and efficacy data to be collected for health interventions (e.g., drugs, diagnostics, devices, therapy protocols) that is performed over phases. http://purl.obolibrary.org/obo/ERO_0000348 case-only study http://purl.obolibrary.org/obo/OBI_0000066 investigation Observational study whereby there is a single group of individuals with specific characteristics. This is a method that analyzes data from a case series and is used in case-crossover studies, in case-specular designs, and in molecular and genetic epidemiology to assess relationships between environmental exposures and genotypes. http://purl.obolibrary.org/obo/OGI_0000007 textual sequence of genetic interval http://purl.obolibrary.org/obo/IAO_0000030 information content entity the textual sequencial sets of 'A,T,C,G' or 'A,U,C,G' represent the primary structure of a genetic interval. http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000003 DNA interval naturally material segment of DNA molecule located in a chromosome http://purl.obolibrary.org/obo/OGI_0000088 mutation http://purl.obolibrary.org/obo/OGI_0000012 genetic variation In genetics, a mutation is a change of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal genetic element. http://purl.obolibrary.org/obo/OGI_0000004 gene http://purl.obolibrary.org/obo/OGI_0000002 genetic interval a genertically dependent continuant that correspond to one or more DNA sequences that carry the coding information required to produce a specific protein, and that protein in turn carries out a particular function within te cell. http://purl.obolibrary.org/obo/OGSF_0000016 genetic association investigation http://purl.obolibrary.org/obo/OBI_0000066 investigation investigation that aims to test whether single-locus alleles or genotype frequencies (or more generally, multilocus haplotype frequencies) differ between two groups of individuals (usually diseased subjects and healthy controls). Genetic association studies are based on the principle that genotypes can be compared "directly", i.e. with the sequences of the actual genomes. http://purl.obolibrary.org/obo/VO_0000278 vaccine function http://purl.obolibrary.org/obo/BFO_0000034 function vaccine function is a function that inheres in a vaccine that induces protective immune response against a disease. It is realized in the immunization process in the host. http://purl.obolibrary.org/obo/VO_0000490 immunization http://purl.obolibrary.org/obo/BFO_0000015 process immunization is a processual entity that primes or modifies an adaptivie immune response to some antigens. http://purl.obolibrary.org/obo/VO_0000491 active immunization http://purl.obolibrary.org/obo/VO_0000490 immunization Active immunization is an immunization process that entails the introduction of a foreign molecule into the body, which causes the body itself to generate adaptive immunity against the target. http://purl.obolibrary.org/obo/VO_0001274 vaccine host role http://purl.obolibrary.org/obo/OBI_0000725 host role a role of host that contains vaccine. It is a role that inheres in an organism that is the target of a vaccine administration (vaccination process). http://purl.obolibrary.org/obo/VO_0001374 vaccinated organism http://purl.obolibrary.org/obo/OBI_0100026 organism an organism that is vaccinated with a vaccine http://purl.obolibrary.org/obo/VO_0000093 mineral salt vaccine adjuvant http://purl.obolibrary.org/obo/VO_0000580 vaccine adjuvant a vaccine adjuvant that is formed as a mineral salt. http://purl.obolibrary.org/obo/VO_0000147 vaccine adjuvant role http://purl.obolibrary.org/obo/VO_0000137 adjuvant role an adjuvant role that inheres in a material entity which is added as part of a vaccine and induces enhanced adaptive immune response to the vaccine antigen. http://purl.obolibrary.org/obo/VO_0000420 pathogen organism component in vaccine http://purl.obolibrary.org/obo/VO_0000179 vaccine component a vaccine component that originates from an organism such as a pathogen or a modified organism. http://purl.obolibrary.org/obo/VO_0000495 induction of adaptive immune response to antigen http://purl.obolibrary.org/obo/VO_0000491 active immunization induction of adaptive immune response to antigen is an active immunization process that results in induction of adaptive immune response to some antigens, for example, in a vaccine. http://purl.obolibrary.org/obo/VO_0000496 disorder prevention http://purl.obolibrary.org/obo/BFO_0000015 process disorder prevention is a processual entity that prevents a disorder that is the physical basis of a disease. http://purl.obolibrary.org/obo/VO_0000497 disorder treatment http://purl.obolibrary.org/obo/BFO_0000015 process disorder treatment is a processual entity that leads to treat a disorder that is the physical basis of a disease. http://purl.obolibrary.org/obo/VO_0000498 modification of adaptive immune response to antigen http://purl.obolibrary.org/obo/VO_0000491 active immunization modification of adaptive immune response to antigen is an active immunization process that results in modification of an adaptive immune response to some antigens, for example, in a therapeutic vaccine. http://purl.obolibrary.org/obo/VO_0000562 therapeutic vaccine function http://purl.obolibrary.org/obo/VO_0000278 vaccine function The therapeutic vaccine function is a function realized by the process of vaccination and leading to induction of an adaptive immune response to the antigens in a vaccine, which ameliorates a specific disorder. http://purl.obolibrary.org/obo/VO_0000580 vaccine adjuvant http://purl.obolibrary.org/obo/VO_0000850 vaccine additive a vaccine component that is chemical substance added to vaccine and enhance and direct immune response to protective antigen. Many of vaccine adjuvants cause a range of serious side-effects. http://purl.obolibrary.org/obo/VO_0000585 immunization objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification immunization objective is the specification of an objective to achieve immunization. http://purl.obolibrary.org/obo/VO_0000630 licensed vaccine role http://purl.obolibrary.org/obo/OBI_0000016 regulation-assigned role licensed vaccine role is a regulation-assigned role that indicates that a vaccine obtains official approval for commercial production and selling on the market. http://purl.obolibrary.org/obo/VO_0000651 Smallpox virus vaccine http://purl.obolibrary.org/obo/VO_0000609 viral vaccine A viral vaccine that protects against infection with Smallpox virus. http://purl.obolibrary.org/obo/VO_0000850 vaccine additive http://purl.obolibrary.org/obo/VO_0000179 vaccine component a vaccine component that is added to the immunogen by the vaccine manufacturer for a specific purpose. Additives include adjuvants, preservatives and stablizers, as well as materials that are added to affect pH and isotonicity. http://purl.obolibrary.org/obo/VO_0000853 vaccine stabilizer http://purl.obolibrary.org/obo/VO_0000850 vaccine additive a vaccine additive that helps to protect the vaccine from adverse conditions such as the freeze-drying process (for those vaccines that are freeze-dried) or heat. http://purl.obolibrary.org/obo/VO_0000885 vaccine preservative role http://purl.obolibrary.org/obo/BFO_0000023 role a role inhers in a vaccine component that when added into a vccine formmulation, it can prevent the growth of bacteria or fungi that inadvertently may be introduced into the vaccine during administrating process or the manufacturing process. http://purl.obolibrary.org/obo/VO_0001479 vaccine target specification http://purl.obolibrary.org/obo/IAO_0000005 objective specification The objective that intends to produce vaccine via the vaccine preparation process. http://purl.obolibrary.org/obo/VO_0003026 vaccine stabilizer role http://purl.obolibrary.org/obo/BFO_0000023 role a role inheres in vaccine component when added into vaccine's formulation, it tends to inhibit the reaction between two or more other vaccine substances in the final vaccine formulation; it also helps to protect the vaccine from adverse conditions such as the freeze-drying process or heat. http://purl.obolibrary.org/obo/VO_0003034 sugar vaccine stabilizer http://purl.obolibrary.org/obo/VO_0000853 vaccine stabilizer a vaccine stabilizer that is specifically made by a sugar. http://purl.obolibrary.org/obo/OGI_0000026 polymorphic site http://purl.obolibrary.org/obo/OGI_0000020 genomic site a genomic site that is occupied by alleles of polymorphism http://purl.obolibrary.org/obo/OGI_0000046 linkage disequilibrium block http://purl.obolibrary.org/obo/OGI_0000006 DNA segment LD block http://purl.obolibrary.org/obo/OGSF_0000012 textual conclusion of genetic susceptibility http://purl.obolibrary.org/obo/IAO_0000144 conclusion textual entity textual conclusion of genetic association http://purl.obolibrary.org/obo/BFO_0000148 zero-dimensional temporal region http://purl.obolibrary.org/obo/BFO_0000008 temporal region temporal instant. http://purl.obolibrary.org/obo/VO_0000851 vaccine preservative http://purl.obolibrary.org/obo/VO_0000850 vaccine additive antimicrobial agent in vaccine http://purl.obolibrary.org/obo/OGSF_0001013 T allele of rs2070874 SNP http://purl.obolibrary.org/obo/OGI_0000033 alternative allele of SNP http://purl.obolibrary.org/obo/OGSF_0001010 T allele of rs1801133 SNP http://purl.obolibrary.org/obo/OGSF_0000007 susceptibility allele of SNP http://purl.obolibrary.org/obo/OGSF_0001014 C allele of rs2243268 SNP http://purl.obolibrary.org/obo/OGI_0000033 alternative allele of SNP http://purl.obolibrary.org/obo/OGSF_0001015 A allele of rs2243290 SNP http://purl.obolibrary.org/obo/OGI_0000033 alternative allele of SNP http://purl.obolibrary.org/obo/OGSF_0001012 A allele of rs839 SNP http://purl.obolibrary.org/obo/OGSF_0000007 susceptibility allele of SNP http://purl.obolibrary.org/obo/OGSF_0001011 G allele of rs9282763 SNP http://purl.obolibrary.org/obo/OGSF_0000007 susceptibility allele of SNP http://purl.obolibrary.org/obo/OGI.owl#CpG_Island CpG Island http://purl.obolibrary.org/obo/OGI_0000042 gene regulatory element http://purl.obolibrary.org/obo/OGI_0000038 allele shared by sibs http://purl.obolibrary.org/obo/OGI_0000008 allele http://purl.obolibrary.org/obo/OGI_0000036 allele of phenotype http://purl.obolibrary.org/obo/OGI_0000008 allele http://purl.obolibrary.org/obo/OGI_0000078 cytogenetic map http://purl.obolibrary.org/obo/OGI_0000074 genetics map http://purl.obolibrary.org/obo/OGSF_0001019 haplotype 1 in IRF1 gene http://purl.obolibrary.org/obo/OGSF_0000006 susceptibility haplotype http://purl.obolibrary.org/obo/OGSF_0001020 haplotype 2 in IL4 gene http://purl.obolibrary.org/obo/OGSF_0000006 susceptibility haplotype http://purl.obolibrary.org/obo/OGI.owl#Polymer polymer http://purl.obolibrary.org/obo/OGI.owl#Biological_Macromolecule biological macromolecule http://purl.obolibrary.org/obo/OGI.owl#Biological_Macromolecule biological macromolecule http://purl.obolibrary.org/obo/OGI.owl#Biological_Molecule biological molecule http://purl.obolibrary.org/obo/OGI.owl#Biological_Small_Molecule biological small molecule http://purl.obolibrary.org/obo/OGI.owl#Biological_Molecule biological molecule http://purl.obolibrary.org/obo/OGI.owl#RNA_Molecule RNA molecule http://purl.obolibrary.org/obo/OGI.owl#Nucleic_Acid nucleic acid http://purl.obolibrary.org/obo/OGI.owl#Nucleic_Acid nucleic acid http://purl.obolibrary.org/obo/OGI.owl#Polymer polymer http://purl.obolibrary.org/obo/OGI.owl#Polypeptide polypeptide http://purl.obolibrary.org/obo/OGI.owl#Polymer polymer http://purl.obolibrary.org/obo/OGI.owl#Protein protein http://purl.obolibrary.org/obo/OGI.owl#Polymer polymer http://purl.obolibrary.org/obo/OGI.owl#Histone histone http://purl.obolibrary.org/obo/OGI.owl#Protein protein http://purl.obolibrary.org/obo/OGI.owl#Coding_RNA_Molecule coding RNA molecule http://purl.obolibrary.org/obo/OGI.owl#RNA_Molecule RNA molecule http://purl.obolibrary.org/obo/OGI.owl#Non_Coding_RNA_Molecule non codling RNA molecule http://purl.obolibrary.org/obo/OGI.owl#RNA_Molecule RNA molecule http://purl.obolibrary.org/obo/OGI.owl#Transcript transcript http://purl.obolibrary.org/obo/OGI.owl#RNA_Molecule RNA molecule http://purl.obolibrary.org/obo/OGI.owl#rRNA ribosomal RNA http://purl.obolibrary.org/obo/OGI.owl#RNA_Molecule RNA molecule http://purl.obolibrary.org/obo/OGI.owl#tRNA transfer RNA http://purl.obolibrary.org/obo/OGI.owl#RNA_Molecule RNA molecule http://purl.obolibrary.org/obo/OGI.owl#miRNA Micro RNAs http://purl.obolibrary.org/obo/OGI.owl#RNA_Molecule RNA molecule http://purl.obolibrary.org/obo/OGI.owl#Primary_Transcript primary transcript http://purl.obolibrary.org/obo/OGI.owl#Transcript transcript http://purl.obolibrary.org/obo/OGI.owl#mRNA messenger RNA http://purl.obolibrary.org/obo/OGI.owl#Transcript transcript http://purl.obolibrary.org/obo/OGSF_0000104 three dimention structure of genetic interval http://purl.obolibrary.org/obo/OGI.owl_0000014 three dimention structure of biological interval http://purl.obolibrary.org/obo/OGI_0000087 genomic aberration http://purl.obolibrary.org/obo/OGI_0000012 genetic variation http://purl.obolibrary.org/obo/OGI_0000016 circular http://purl.obolibrary.org/obo/OGI_0000013 primary structure of biological interval http://purl.obolibrary.org/obo/OGI_0000017 linear http://purl.obolibrary.org/obo/OGI_0000013 primary structure of biological interval http://purl.obolibrary.org/obo/OGSF_0000103 two dimentional structure of genetic interval http://purl.obolibrary.org/obo/OGI_0000015 two dimention structure of biological interval http://purl.obolibrary.org/obo/OGI_0000081 gene family http://purl.obolibrary.org/obo/OGI_0000019 genetic interval aggregate http://purl.obolibrary.org/obo/OGI_0000102 interactive gene group http://purl.obolibrary.org/obo/OGI_0000019 genetic interval aggregate http://purl.obolibrary.org/obo/OGI_0000080 contig http://purl.obolibrary.org/obo/OGI_0000019 genetic interval aggregate http://purl.obolibrary.org/obo/OGI_0000028 location on cytogenetic map http://purl.obolibrary.org/obo/OGI_0000021 location on map http://purl.obolibrary.org/obo/OGI_0000034 location on linkage map http://purl.obolibrary.org/obo/OGI_0000021 location on map http://purl.obolibrary.org/obo/OGI_0000032 location on genetic physical map http://purl.obolibrary.org/obo/OGI_0000021 location on map http://purl.obolibrary.org/obo/OGI_0000023 gene locus http://purl.obolibrary.org/obo/OGI_0000022 locus http://purl.obolibrary.org/obo/OGI_0000024 linked loci http://purl.obolibrary.org/obo/OGI_0000022 locus http://purl.obolibrary.org/obo/OGI_0000030 entrez gene cytogenetic band http://purl.obolibrary.org/obo/OGI_0000028 location on cytogenetic map http://purl.obolibrary.org/obo/OGI_0000029 ensembl cytogenetic band http://purl.obolibrary.org/obo/OGI_0000028 location on cytogenetic map http://purl.obolibrary.org/obo/OGI_0000031 HGNC cytogenetic band http://purl.obolibrary.org/obo/OGI_0000028 location on cytogenetic map http://purl.obolibrary.org/obo/OGSF_0001003 DRB1*15:01 http://purl.obolibrary.org/obo/OGSF_0000009 susceptibility allele http://purl.obolibrary.org/obo/OGI_0000061 allele of copy number polymorphism http://purl.obolibrary.org/obo/OGI_0000037 allele of polymorphism http://purl.obolibrary.org/obo/OGI_0000060 allel of repeat sequnce polymorphism http://purl.obolibrary.org/obo/OGI_0000037 allele of polymorphism http://purl.obolibrary.org/obo/OGI_0000053 protein marker http://purl.obolibrary.org/obo/OGI_0000051 genetic marker http://purl.obolibrary.org/obo/OGI_0000052 DNA marker http://purl.obolibrary.org/obo/OGI_0000051 genetic marker http://purl.obolibrary.org/obo/OGI_0000058 STS microsatellite marker http://purl.obolibrary.org/obo/OGI_0000056 microsatellite marker http://purl.obolibrary.org/obo/OGI.owl#STS_Non_Polymorphic_Marker STS non polymorphic marker http://purl.obolibrary.org/obo/OGI_0000055 STS marker http://purl.obolibrary.org/obo/OGI_0000103 ancestrol allele of SNP http://purl.obolibrary.org/obo/OGI_0000062 allele of SNP http://purl.obolibrary.org/obo/OGI_0000065 genetic marker probe http://purl.obolibrary.org/obo/OGI_0000064 probe http://purl.obolibrary.org/obo/OGI_0000079 sequence feature map http://purl.obolibrary.org/obo/OGI_0000077 genetic physical map http://purl.obolibrary.org/obo/OGI_0000091 copy number polymorphism http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGI_0000095 restriction fragment length polymorphism http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGI_0000092 deletion polymorphism http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGI_0000093 insertion polymorphism http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGI_0000096 single-strand conformatinal polymorphism http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGI_0000090 SNP http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGI_0000094 repeat sequence polymorphism http://purl.obolibrary.org/obo/OGI_0000089 genetic polymorohism http://purl.obolibrary.org/obo/OGSF_0000011 susceptibility gene http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor http://purl.obolibrary.org/obo/OGSF_0000014 susceptibility interactive gene group http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor http://purl.obolibrary.org/obo/OGSF_0000034 susceptibility SNP http://purl.obolibrary.org/obo/OGSF_0000004 genetic susceptibility factor http://purl.obolibrary.org/obo/OGSF_0000022 human case group http://purl.obolibrary.org/obo/OGSF_0000021 human study subject group http://purl.obolibrary.org/obo/OGSF_0000023 human control group http://purl.obolibrary.org/obo/OGSF_0000021 human study subject group http://purl.obolibrary.org/obo/OGSF_0001022 human vaccinee experiencing systematic adverse event http://purl.obolibrary.org/obo/OGSF_0001021 human vaccinee http://purl.obolibrary.org/obo/OGSF_0001042 wheezing AE after influenza vaccination http://purl.obolibrary.org/obo/OAE_0000053 wheezing AE http://purl.obolibrary.org/obo/OGSF_0001028 systematic adverse event after smallpox vaccination http://purl.obolibrary.org/obo/OAE_0000063 systematic adverse event http://purl.obolibrary.org/obo/OGSF_0001006 multiple sclerosis AE after Pandemrix vaccination http://purl.obolibrary.org/obo/OAE_0000481 multiple sclerosis AE http://purl.obolibrary.org/obo/VO_0000173 attenuated http://purl.obolibrary.org/obo/PATO_0002146 virulence http://purl.obolibrary.org/obo/NCBITaxon_35237 dsDNA viruses, no RNA stage http://purl.obolibrary.org/obo/NCBITaxon_10239 Viruses http://purl.obolibrary.org/obo/NCBITaxon_439488 ssRNA viruses http://purl.obolibrary.org/obo/NCBITaxon_10239 Viruses http://purl.obolibrary.org/obo/NCBITaxon_11320 Influenza A virus http://purl.obolibrary.org/obo/NCBITaxon_197911 Influenzavirus A http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000001 entity http://purl.obolibrary.org/obo/BFO_0000008 temporal region http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000011 spatiotemporal region http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000028 three-dimensional spatial region http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000034 function http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/OGI_0000011 biological interval structure http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/OGI_0000018 genetic marker role http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/VO_0000415 vaccine additive role http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/VO_0001275 immunization target role http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/OGI_0000074 genetics map http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/OGI.owl#Biological_Molecule biological molecule http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/OGI.owl#Book book http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/OGSF_0000025 human study subject group size http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/OGSF_0000028 odds ratio http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/OGSF_0000020 human study subject http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/OGSF_0001000 multiple sclerosis AE patient http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/VO_0000299 company http://purl.obolibrary.org/obo/OBI_0000245 organization http://purl.obolibrary.org/obo/NCBITaxon_10239 Viruses http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/OGSF_0000026 odds ratio measurement http://purl.obolibrary.org/obo/OBI_0200000 data transformation http://purl.obolibrary.org/obo/OGSF_0000027 logistic regression measurement http://purl.obolibrary.org/obo/OBI_0200000 data transformation http://purl.obolibrary.org/obo/OGSF_0001007 pandemrix vaccination http://purl.obolibrary.org/obo/VO_0000002 vaccination http://purl.obolibrary.org/obo/OGSF_0001041 smallpox vaccination http://purl.obolibrary.org/obo/VO_0000002 vaccination http://purl.obolibrary.org/obo/OGSF_0001043 influenza vaccination http://purl.obolibrary.org/obo/VO_0000002 vaccination http://purl.obolibrary.org/obo/OGI_0000063 allele of microsatellite http://purl.obolibrary.org/obo/OGI_0000060 allel of repeat sequnce polymorphism http://purl.obolibrary.org/obo/OGI_0000057 non STS microsatellite marker http://purl.obolibrary.org/obo/OGI_0000056 microsatellite marker http://purl.obolibrary.org/obo/OGI_0000097 microsatellite polymorphism http://purl.obolibrary.org/obo/OGI_0000094 repeat sequence polymorphism http://purl.obolibrary.org/obo/OGI_0000098 minisatellite polymorphism http://purl.obolibrary.org/obo/OGI_0000094 repeat sequence polymorphism http://purl.obolibrary.org/obo/OGI_0000099 satellite polymorphism http://purl.obolibrary.org/obo/OGI_0000094 repeat sequence polymorphism http://purl.obolibrary.org/obo/NCBITaxon_114727 H1N1 subtype http://purl.obolibrary.org/obo/NCBITaxon_11320 Influenza A virus http://purl.obolibrary.org/obo/OGI_0000009 genetic interval base residue http://purl.obolibrary.org/obo/OGI_0000001 biological material interval http://purl.obolibrary.org/obo/OGI_0000003 DNA interval http://purl.obolibrary.org/obo/OGI_0000002 genetic interval http://purl.obolibrary.org/obo/OGI_0000005 RNA interval http://purl.obolibrary.org/obo/OGI_0000002 genetic interval http://purl.obolibrary.org/obo/OGI_0000067 adenine residue http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/OGI_0000068 cytosine residue http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/OGI_0000069 guanine residue http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/OGI_0000070 thymine residue http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/NCBITaxon_10255 Variola virus http://purl.obolibrary.org/obo/NCBITaxon_10241 Chordopoxvirinae http://purl.obolibrary.org/obo/NCBITaxon_197911 Influenzavirus A http://purl.obolibrary.org/obo/NCBITaxon_11308 Orthomyxoviridae http://purl.obolibrary.org/obo/NCBITaxon_197912 Influenzavirus B http://purl.obolibrary.org/obo/NCBITaxon_11308 Orthomyxoviridae http://purl.obolibrary.org/obo/NCBITaxon_197913 Influenzavirus C http://purl.obolibrary.org/obo/NCBITaxon_11308 Orthomyxoviridae http://purl.obolibrary.org/obo/NCBITaxon_35324 unclassified Orthomyxoviridae http://purl.obolibrary.org/obo/NCBITaxon_11308 Orthomyxoviridae http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_10241 Chordopoxvirinae http://purl.obolibrary.org/obo/NCBITaxon_35237 dsDNA viruses, no RNA stage http://purl.obolibrary.org/obo/NCBITaxon_11308 Orthomyxoviridae http://purl.obolibrary.org/obo/NCBITaxon_35301 ssRNA negative-strand viruses http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_35301 ssRNA negative-strand viruses http://purl.obolibrary.org/obo/NCBITaxon_439488 ssRNA viruses http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/OGI_0000084 nuclear genome http://purl.obolibrary.org/obo/SO_0001026 genome http://purl.obolibrary.org/obo/OGI_0000059 SNP marker http://purl.obolibrary.org/obo/OGI_0000054 polymorphic DNA marker http://purl.obolibrary.org/obo/OGI_0000056 microsatellite marker http://purl.obolibrary.org/obo/OGI_0000054 polymorphic DNA marker http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/OGI_0000009 genetic interval base residue http://purl.obolibrary.org/obo/OGI.owl_0000014 three dimention structure of biological interval http://purl.obolibrary.org/obo/OGI_0000011 biological interval structure http://purl.obolibrary.org/obo/OGI_0000013 primary structure of biological interval http://purl.obolibrary.org/obo/OGI_0000011 biological interval structure http://purl.obolibrary.org/obo/OGI_0000015 two dimention structure of biological interval http://purl.obolibrary.org/obo/OGI_0000011 biological interval structure http://purl.obolibrary.org/obo/OBI_0000885 secondary structure of sequence macromolecule http://purl.obolibrary.org/obo/OGI_0000011 biological interval structure http://purl.obolibrary.org/obo/OGI_0000025 amino acid sequence http://purl.obolibrary.org/obo/OGI_0000014 biological sequence http://purl.obolibrary.org/obo/OGI_0000071 nucleotide sequence http://purl.obolibrary.org/obo/OGI_0000014 biological sequence http://purl.obolibrary.org/obo/OGI.owl#Genomic_DNA genomic DNA http://purl.obolibrary.org/obo/OGI.owl#DNA_Molecule Dexyribonuleic acid molecule http://purl.obolibrary.org/obo/OGI.owl#cDNA complementary DNA http://purl.obolibrary.org/obo/OGI.owl#DNA_Molecule Dexyribonuleic acid molecule http://purl.obolibrary.org/obo/OGI.owl#msDNA multicopy single-stranded DNA http://purl.obolibrary.org/obo/OGI.owl#DNA_Molecule Dexyribonuleic acid molecule http://purl.obolibrary.org/obo/OGI.owl#mtDNA Mitochondrial DNA http://purl.obolibrary.org/obo/OGI.owl#DNA_Molecule Dexyribonuleic acid molecule http://purl.obolibrary.org/obo/NCBITaxon_11309 unidentified influenza virus http://purl.obolibrary.org/obo/NCBITaxon_35324 unclassified Orthomyxoviridae http://purl.obolibrary.org/obo/OGI_0000066 RNA segment http://purl.obolibrary.org/obo/OGI_0000005 RNA interval http://purl.obolibrary.org/obo/OGI_1000004 start point of interval http://purl.obolibrary.org/obo/OGI_1000002 boundary point of interval http://purl.obolibrary.org/obo/OGI_1000003 end point of interval http://purl.obolibrary.org/obo/OGI_1000002 boundary point of interval http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/OGI_0000042 gene regulatory element http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000043 haplotype http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000040 chromosome part http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000044 intergenic region http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000045 intron http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000048 mutant http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000049 part of exon http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000050 part of intron http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000041 exon http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000047 linkage interval http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000039 CDS http://purl.obolibrary.org/obo/OGI_0000006 DNA segment http://purl.obolibrary.org/obo/OGI_0000055 STS marker http://purl.obolibrary.org/obo/OGI_0000052 DNA marker http://purl.obolibrary.org/obo/OGI_0000054 polymorphic DNA marker http://purl.obolibrary.org/obo/OGI_0000052 DNA marker http://purl.obolibrary.org/obo/OGI_0000101 segmental Mutation http://purl.obolibrary.org/obo/OGI_0000088 mutation http://purl.obolibrary.org/obo/OGI_0000100 point mutation http://purl.obolibrary.org/obo/OGI_0000088 mutation http://purl.obolibrary.org/obo/OGI.owl#Polypeptide_Encoding_Gene polypeptide coding gene http://purl.obolibrary.org/obo/OGI_0000004 gene http://purl.obolibrary.org/obo/OGI.owl#Pseudogene pseudogene http://purl.obolibrary.org/obo/OGI_0000004 gene http://purl.obolibrary.org/obo/OGI.owl#RNA_Gene RNA gene http://purl.obolibrary.org/obo/OGI_0000004 gene http://purl.obolibrary.org/obo/OGSF_0000030 human gene http://purl.obolibrary.org/obo/OGI_0000004 gene http://purl.obolibrary.org/obo/OGSF_0001004 HLA DBR1 gene http://purl.obolibrary.org/obo/OGSF_0000030 human gene http://purl.obolibrary.org/obo/OGSF_0001018 IL4 gene http://purl.obolibrary.org/obo/OGSF_0000030 human gene http://purl.obolibrary.org/obo/OGSF_0001016 MTHFR gene http://purl.obolibrary.org/obo/OGSF_0000030 human gene http://purl.obolibrary.org/obo/OGSF_0001017 IRF1 gene http://purl.obolibrary.org/obo/OGSF_0000030 human gene http://purl.obolibrary.org/obo/OGSF_0000035 genetic association with adverse event clinical trail http://purl.obolibrary.org/obo/OGSF_0000016 genetic association investigation http://purl.obolibrary.org/obo/OGI_0000073 DNA sequence http://purl.obolibrary.org/obo/OGI_0000071 nucleotide sequence http://purl.obolibrary.org/obo/OGI_0000072 RNA sequence http://purl.obolibrary.org/obo/OGI_0000071 nucleotide sequence http://purl.obolibrary.org/obo/OGSF_0001021 human vaccinee http://purl.obolibrary.org/obo/VO_0001374 vaccinated organism http://purl.obolibrary.org/obo/VO_0000624 whole pathogen organism as vaccine component http://purl.obolibrary.org/obo/VO_0000420 pathogen organism component in vaccine http://purl.obolibrary.org/obo/SO_0001026 genome A genome is the sum of genetic material within a cell or virion. http://purl.obolibrary.org/obo/OGI_1000001 biomolecule boundary biomolecule boundary is the surface of a biomolecule ,which is a lower dimensional part of a molecule. biomolecule bounday can separate a biological molecule from the rest of the existing entities in the world.(for example, DNA molecule is separate from rest part in the cell nucleus by DNA molecule boundary) http://purl.obolibrary.org/obo/OGI_0000019 genetic interval aggregate http://purl.obolibrary.org/obo/OGI_0000021 location on map http://purl.obolibrary.org/obo/OGSF_0000021 human study subject group http://purl.obolibrary.org/obo/BFO_0000001 entity http://purl.obolibrary.org/obo/OGI.owl#DNA_Molecule Dexyribonuleic acid molecule http://purl.obolibrary.org/obo/OGI_0000020 genomic site http://purl.obolibrary.org/obo/OGI_1000002 boundary point of interval http://purl.obolibrary.org/obo/RO_0002218 has active participant http://purl.obolibrary.org/obo/BFO_0000057 has participant at some time has agent x has participant y if and only if x realizes some active role that inheres in y http://purl.obolibrary.org/obo/RO_0002217 actively participates in http://purl.obolibrary.org/obo/BFO_0000056 participates_in agent in x actively participates in y if and only if x participates in y and x realizes some active role http://purl.obolibrary.org/obo/RO_0002224 starts with http://purl.obolibrary.org/obo/RO_0002222 temporally related to started by x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002230 ends with http://purl.obolibrary.org/obo/RO_0002222 temporally related to finished by x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/BFO_0000121 has temporal part http://purl.obolibrary.org/obo/BFO_0000117 has occurrent part [copied from inverse property 'temporal part of'] b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003]) http://purl.obolibrary.org/obo/BFO_0000139 temporal part of http://purl.obolibrary.org/obo/BFO_0000132 part of occurrent b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003]) http://purl.obolibrary.org/obo/BFO_0000186 part of continuant at all times that whole exists http://purl.obolibrary.org/obo/BFO_0000176 part of continuant at some time [copied from inverse property 'has continuant part at all times'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) http://purl.obolibrary.org/obo/inheres_in inheres_in http://purl.obolibrary.org/obo/inheres_in_part_of inheres_in_part_of A relation between a dependent continuant D and an entity E. D inheres_in E iff: given any d that instantiates D at t, there exists some e that instantiates E at t and d *inheres_in* e at t. Here *inheres_in* is the primitive instance level relation. http://purl.obolibrary.org/obo/OBI_0000293 has_specified_input http://purl.obolibrary.org/obo/BFO_0000057 has participant at some time A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. http://purl.obolibrary.org/obo/OBI_0000299 has_specified_output http://purl.obolibrary.org/obo/BFO_0000057 has participant at some time A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. http://purl.obolibrary.org/obo/OBI_0000312 is_specified_output_of http://purl.obolibrary.org/obo/BFO_0000056 participates_in A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 is part of inverse of starts with http://purl.obolibrary.org/obo/BFO_0000177 part of continuant at all times http://purl.obolibrary.org/obo/BFO_0000176 part of continuant at some time [copied from inverse property 'has continuant part at all times that part exists'] forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t) http://purl.obolibrary.org/obo/BFO_0000187 has continuant part at all times that part exists http://purl.obolibrary.org/obo/BFO_0000178 has continuant part at some time forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t) http://purl.obolibrary.org/obo/BFO_0000052 inheres in at all times http://purl.obolibrary.org/obo/BFO_0000070 specifically depends on at all times b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002]) http://purl.obolibrary.org/obo/BFO_0000053 bearer of at some time http://purl.obolibrary.org/obo/BFO_0000125 has specific dependent at some time b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004]) http://purl.obolibrary.org/obo/BFO_0000087 has role at some time http://purl.obolibrary.org/obo/BFO_0000053 bearer of at some time a has_role b at t =Def. b role_of a at t. (axiom label in BFO2 Reference: [068-001]) http://purl.obolibrary.org/obo/BFO_0000085 has function at some time http://purl.obolibrary.org/obo/BFO_0000053 bearer of at some time a has_function b at t =Def. b function_of a at t. (axiom label in BFO2 Reference: [070-001]) http://purl.obolibrary.org/obo/BFO_0000110 has continuant part at all times http://purl.obolibrary.org/obo/BFO_0000178 has continuant part at some time b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) http://purl.obolibrary.org/obo/BFO_0000118 has proper occurrent part http://purl.obolibrary.org/obo/BFO_0000117 has occurrent part b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001 http://purl.obolibrary.org/obo/RO_0002229 ends http://purl.obolibrary.org/obo/BFO_0000050 is part of inverse of ends with http://purl.obolibrary.org/obo/role_of role_of http://purl.obolibrary.org/obo/inheres_in inheres_in A relation between a role R and an entity E. R role_of E iff: R inheres_in E and R is a role http://purl.obolibrary.org/obo/BFO_0000060 preceded by http://purl.obolibrary.org/obo/RO_0002089 starts_before preceded_by http://purl.obolibrary.org/obo/RO_0002081 before_or_simultaneous_with http://purl.obolibrary.org/obo/RO_0002222 temporally related to <= http://purl.obolibrary.org/obo/RO_0002087 immediately_preceded_by http://purl.obolibrary.org/obo/BFO_0000062 is preceded by starts_at_end_of http://purl.obolibrary.org/obo/RO_0002090 immediately_precedes http://purl.obolibrary.org/obo/BFO_0000060 preceded by meets http://purl.obolibrary.org/obo/BFO_0000062 is preceded by http://purl.obolibrary.org/obo/RO_0002086 ends_after preceded_by http://purl.obolibrary.org/obo/RO_0002091 starts_during http://purl.obolibrary.org/obo/RO_0002222 temporally related to io http://purl.obolibrary.org/obo/RO_0002092 happens_during http://purl.obolibrary.org/obo/RO_0002093 ends_during during http://purl.obolibrary.org/obo/RO_0002093 ends_during http://purl.obolibrary.org/obo/RO_0002222 temporally related to overlaps http://purl.obolibrary.org/obo/RO_0002085 encompasses http://purl.obolibrary.org/obo/RO_0002088 during_which_starts di http://purl.obolibrary.org/obo/RO_0002083 before http://purl.obolibrary.org/obo/RO_0002081 before_or_simultaneous_with http://purl.obolibrary.org/obo/RO_0002082 simultaneous_with http://purl.obolibrary.org/obo/RO_0002081 before_or_simultaneous_with http://purl.obolibrary.org/obo/OGSF_0001008 is positive supporting statistical evidence of http://purl.obolibrary.org/obo/IAO_0000136 is about http://purl.obolibrary.org/obo/OGSF_0001009 is negative statistical evidence of http://purl.obolibrary.org/obo/IAO_0000136 is about http://purl.obolibrary.org/obo/BFO_0000086 has quality at some time http://purl.obolibrary.org/obo/BFO_0000053 bearer of at some time http://purl.obolibrary.org/obo/RO_0002089 starts_before http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002086 ends_after http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002084 during_which_ends http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002088 during_which_starts http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/BFO_0000070 specifically depends on at all times http://purl.obolibrary.org/obo/BFO_0000169 specifically depends on at some time http://purl.obolibrary.org/obo/BFO_0000154 temporal projection of spatiotemporal http://purl.obolibrary.org/obo/BFO_0000157 during which exists http://purl.obolibrary.org/obo/BFO_0000156 has temporal occupant http://purl.obolibrary.org/obo/BFO_0000157 during which exists http://purl.obolibrary.org/obo/BFO_0000153 projects onto temporal region http://purl.obolibrary.org/obo/BFO_0000108 exists at http://purl.obolibrary.org/obo/BFO_0000155 occupies temporal region http://purl.obolibrary.org/obo/BFO_0000108 exists at http://purl.obolibrary.org/obo/OBI_0000304 is_manufactured_by has_manufacturer c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the "Manufacturer Role", and those people/and or machines were members or of directed by the organization to do this. http://purl.obolibrary.org/obo/OGSF_0000013 is_allele_of_gene allele of is a relation to link an allele with its original form http://purl.obolibrary.org/obo/IAO_0000136 is about is_about is a (currently) primitive relation that relates an information artifact to an entity. http://purl.obolibrary.org/obo/OBI_0000417 achieves_planned_objective This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process. http://purl.obolibrary.org/obo/BFO_0000117 has occurrent part b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001]) http://purl.obolibrary.org/obo/BFO_0000132 part of occurrent [copied from inverse property 'has occurrent part'] b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001]) http://purl.obolibrary.org/obo/BFO_0000176 part of continuant at some time [copied from inverse property 'has continuant part at some time'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) http://purl.obolibrary.org/obo/BFO_0000178 has continuant part at some time b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) http://purl.obolibrary.org/obo/bearer_of bearer_of A relation between an entity and a dependent continuant; the reciprocal relation of inheres_in http://purl.obolibrary.org/obo/BFO_0000056 participates_in participates_in http://purl.obolibrary.org/obo/BFO_0000057 has participant at some time has_participant http://purl.obolibrary.org/obo/BFO_0000126 has spatiotemporal occupant http://purl.obolibrary.org/obo/BFO_0000130 occupies spatiotemporal region http://purl.obolibrary.org/obo/BFO_0000151 projects onto spatial region at some time http://purl.obolibrary.org/obo/BFO_0000152 spatial projection of spatiotemporal at some time http://purl.obolibrary.org/obo/BFO_0000054 realized in http://purl.obolibrary.org/obo/BFO_0000055 realizes http://purl.obolibrary.org/obo/chebi#is_substituent_group_from is substituent group from http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/BFO_0000083 occupies spatial region at some time http://purl.obolibrary.org/obo/BFO_0000123 has spatial occupant at some time http://purl.obolibrary.org/obo/BFO_0000125 has specific dependent at some time http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/OGSF_0001031 hasOddsRatio http://purl.obolibrary.org/obo/BFO_0000050 is part of http://purl.obolibrary.org/obo/OGSF_0001032 hasPvalue http://purl.obolibrary.org/obo/BFO_0000169 specifically depends on at some time http://purl.obolibrary.org/obo/ERO_0001518 has_phase http://purl.obolibrary.org/obo/OGSF_0000024 hasSize http://purl.obolibrary.org/obo/BFO_0000058 is concretization of http://purl.obolibrary.org/obo/BFO_0000059 concretizes at some time http://purl.obolibrary.org/obo/BFO_0000157 during which exists http://purl.obolibrary.org/obo/BFO_0000108 exists at http://purl.obolibrary.org/obo/so_has_part has_part http://purl.obolibrary.org/obo/so_member_of member_of http://purl.obolibrary.org/obo/so_variant_of variant_of http://purl.obolibrary.org/obo/VO_0001243 vaccine immunization for host http://purl.obolibrary.org/obo/VO_0003355 vaccine immunization against microbe http://purl.obolibrary.org/obo/inheres_in_part_of inheres_in_part_of