Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/OBI_0002465 age since culture seeding measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum age of culture An age measurement datum that is the result of the measurement of the age of a cell since cultured (the process of seeding cells onto a culture dish). http://purl.obolibrary.org/obo/OBI_0002479 sequence read length measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum read length, read length measurement datum A measurement datum that is the result of the measurement of the number of bases in a DNA or RNA sequence. http://purl.obolibrary.org/obo/OBI_0002480 sequencing library input quantity measurement datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum library input amount A scalar measurement datum that indicates the amount of sequencing library used as input for a sequencer. http://purl.obolibrary.org/obo/OBI_0002482 specimen harvest quantity http://purl.obolibrary.org/obo/IAO_0000109 measurement datum harvest quantity A scalar measurement datum that indicates the amount of specimen collected. http://purl.obolibrary.org/obo/OBI_0002137 RNA Integrity Number value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification RIN value specification A value specification that specifies the value of the RNA Integrity Number as a real value between 1 (most degraded) and 10 (most intact). http://purl.obolibrary.org/obo/IAO_0000005 objective specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity goal specification a directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved. http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/IAO_0000030 information content entity data a data item is an information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements. http://purl.obolibrary.org/obo/IAO_0000573 line graph http://purl.obolibrary.org/obo/IAO_0000038 graph line chart A line graph is a type of graph created by connecting a series of data points together with a line. http://purl.obolibrary.org/obo/OBI_0000070 assay http://purl.obolibrary.org/obo/OBI_0000011 planned process scientific observation A planned process with the objective to produce information about the material entity that is the evaluant, by physically examining it or its proxies. http://purl.obolibrary.org/obo/OBI_0000086 reagent role http://purl.obolibrary.org/obo/BFO_0000023 role reagent A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer. http://purl.obolibrary.org/obo/OBI_0000094 material processing http://purl.obolibrary.org/obo/OBI_0000011 planned process material transformation A planned process which results in physical changes in a specified input material http://purl.obolibrary.org/obo/OBI_0000245 organization http://purl.obolibrary.org/obo/BFO_0000040 material entity organisation An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members. http://purl.obolibrary.org/obo/OBI_0000392 information processor function http://purl.obolibrary.org/obo/BFO_0000034 function data processor function An information processor function is a function that converts information from one form to another, by a lossless process or an extraction process. http://purl.obolibrary.org/obo/OBI_0000456 material transformation objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification artifact creation objective an objective specifiction that creates an specific output object from input materials. http://purl.obolibrary.org/obo/OBI_0000659 specimen collection process http://purl.obolibrary.org/obo/OBI_0000011 planned process specimen collection A planned process with the objective of collecting a specimen. http://purl.obolibrary.org/obo/OBI_0000801 spike train datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum spike train measurement A measurement datum which represents information about an ordered series of action potentials in an organism's CNS measured over time. http://purl.obolibrary.org/obo/OBI_0000938 categorical measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum nominal mesurement datum A measurement datum that is reported on a categorical scale http://purl.obolibrary.org/obo/OBI_0000944 handedness assay http://purl.obolibrary.org/obo/OBI_0000070 assay handedness test A handedness assay measures the unequal distribution of fine motor skill between the left and right hands typically in human subjects by means of some questionnaire and scoring procedure. http://purl.obolibrary.org/obo/OBI_0000968 device http://purl.obolibrary.org/obo/OBI_0000047 processed material instrument A material entity that is designed to perform a function in a scientific investigation, but is not a reagent. http://purl.obolibrary.org/obo/OBI_0000970 scalar score from composite inputs http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum questionaire score A measurement datum which is the result of combining multiple datum. For example, a mean or summary score. http://purl.obolibrary.org/obo/OBI_0001171 half life datum (t 1/2) http://purl.obolibrary.org/obo/IAO_0000416 time measurement datum t 1/2 The time it takes for 50% of a class of stochastic processes to occur. http://purl.obolibrary.org/obo/OBI_0001508 sampling time measurement datum http://purl.obolibrary.org/obo/IAO_0000416 time measurement datum time point A time measurement datum when an observation is made or a sample is taken from a material as measured from some reference point. http://purl.obolibrary.org/obo/OBI_0001619 specimen collection time measurement datum http://purl.obolibrary.org/obo/IAO_0000416 time measurement datum collection date A time measurement datum that is the measure of the time when the specimens are collected. http://purl.obolibrary.org/obo/OBI_0001620 latitude coordinate measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum latitude A measurement datum that is the measure of the latitude coordinate of a site. http://purl.obolibrary.org/obo/OBI_0001621 longitude coordinate measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum longitude A measurement datum that is the measure of the longitude coordinate of a site. http://purl.obolibrary.org/obo/OBI_0001877 random access memory http://purl.obolibrary.org/obo/IAO_0000178 material information bearer RAM Random-access memory (RAM) is a form of computer data storage. A random-access device allows stored data to be accessed directly in any random order. In contrast, other data storage media such as hard disks, CDs, DVDs and magnetic tape, as well as early primary memory types such as drum memory, read and write data only in a predetermined order, consecutively, because of mechanical design limitations. Therefore, the time to access a given data location varies significantly depending on its physical location http://purl.obolibrary.org/obo/OBI_0001905 secondary cultured cell population http://purl.obolibrary.org/obo/OBI_0100060 cultured cell population secondary cell culture sample A cultured cell population that is derived through one or more passages in culture. http://purl.obolibrary.org/obo/OBI_0001908 testable hypothesis http://purl.obolibrary.org/obo/IAO_0000030 information content entity hypothesis An information content entity that expresses an assertion that is intended to be tested. http://purl.obolibrary.org/obo/OBI_0001913 computation run time http://purl.obolibrary.org/obo/IAO_0000416 time measurement datum computation run time datum computation run time is a time measurement datum which corresponds the time expressed in second, minute, hour necessary for a computer program to complete a process execution, for example genome assembly. It is an important metrics as it indicates the resource occupancy and computer program efficiency. http://purl.obolibrary.org/obo/OBI_0001940 N50 http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum weighted median item size the weighted median item size or N50 is a weighted median of the lengths of items, equal to the length of the longest item i such that the sum of the lengths of items greater than or equal in length to i is greater than or equal to half the length of all of the items. With regard to assemblies the items are typically contigs or scaffolds. It therefore denotes the ability of the software to create contigs and provides information about the resulting sequence assembly http://purl.obolibrary.org/obo/OBI_0100060 cultured cell population http://purl.obolibrary.org/obo/OBI_0000047 processed material cell culture sample A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history. http://purl.obolibrary.org/obo/OBI_0200000 data transformation http://purl.obolibrary.org/obo/OBI_0000011 planned process data processing A planned process that produces output data from input data. http://purl.obolibrary.org/obo/OBI_0500000 study design http://purl.obolibrary.org/obo/IAO_0000104 plan specification experimental design A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution. http://purl.obolibrary.org/obo/OBI_0600037 cell culture splitting http://purl.obolibrary.org/obo/OBI_0600014 material component separation cell culture passaging The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing http://purl.obolibrary.org/obo/OBI_1110087 donor http://purl.obolibrary.org/obo/BFO_0000023 role donor role A role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro. http://purl.obolibrary.org/obo/SO_0000001 region http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant sequence A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids. http://purl.obolibrary.org/obo/CL_0000057 fibroblast http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell primary dermal fibroblast A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. http://purl.obolibrary.org/obo/DOID_17 musculoskeletal system disease http://purl.obolibrary.org/obo/DOID_7 disease of anatomical entity "Musuloskeletal disease" EXACT [SNOMEDCT_2005_07_31:268047003] A disease of anatomical entity that occurs in the muscular and/or skeletal system. http://purl.obolibrary.org/obo/DOID_7 disease of anatomical entity http://www.ebi.ac.uk/efo/EFO_0000408 disease "disease of set of heterogenous clusters" EXACT [] A disease that manifests in a defined anatomical structure. http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity polymer A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/OBI_0002210 histologic grade according to the Fuhrman Nuclear Grading System http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification Histologic Grade (Fuhrman Nuclear Grading System) A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System. http://purl.obolibrary.org/obo/OBI_0002224 pathologic primary tumor stage for colon and rectum according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pT: Pathologic spread colorectal primary tumor (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002232 pathologic primary tumor stage for lung according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pT: Pathologic spread lung primary tumor (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002243 pathologic primary tumor stage for kidney according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pT: Pathologic spread kidney primary tumor (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002256 pathologic primary tumor stage for ovary according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pT: Pathologic spread ovarian primary tumor (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002270 pathologic lymph node stage for colon and rectum according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pN: Pathologic spread colon lymph nodes (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes. http://purl.obolibrary.org/obo/OBI_0002279 pathologic lymph node stage for lung according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pN: Pathologic spread colon lymph nodes (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes. http://purl.obolibrary.org/obo/OBI_0002284 pathologic lymph node stage for kidney according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pN: Pathologic spread kidney lymph nodes (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes. http://purl.obolibrary.org/obo/OBI_0002287 pathologic lymph node stage for ovary according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification pN: Pathologic spread ovarian lymph nodes (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes. http://purl.obolibrary.org/obo/OBI_0002290 pathologic distant metastases stage for colon according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification M: colon distant metastases (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002298 pathologic distant metastases stage for lung according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification M: lung distant metastases (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002306 pathologic distant metastases stage for kidney according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification M: kidney distant Metastases (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002310 pathologic distant metastases stage for ovary according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification M: ovarian distant metastases (AJCC 7th Edition) A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery. http://purl.obolibrary.org/obo/OBI_0002314 clinical tumor stage group according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification Clinical tumor stage group (AJCC 7th Edition) A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems. http://purl.obolibrary.org/obo/OBI_0002326 International Federation of Gynecology and Obstetrics cervical cancer stage value specification http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification Clinical FIGO stage A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems. http://purl.obolibrary.org/obo/OBI_0002341 International Federation of Gynecology and Obstetrics ovarian cancer stage value specification http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification Pathologic Tumor Stage Grouping for ovarian cancer (FIGO) A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system. http://purl.obolibrary.org/obo/OBI_0002356 performance status value specification http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification Performance Status Scale A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life). http://purl.obolibrary.org/obo/OBI_0002357 Eastern Cooperative Oncology Group score value specification http://purl.obolibrary.org/obo/OBI_0002356 performance status value specification ECOG score A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient. http://purl.obolibrary.org/obo/OBI_0002363 Karnofsky score vaue specification http://purl.obolibrary.org/obo/OBI_0002356 performance status value specification Karnofsky Score A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment. http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity http://purl.obolibrary.org/obo/BFO_0000040 material entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/BFO_0000040 material entity A chemical entity constituting the smallest component of an element having the chemical properties of the element. http://purl.obolibrary.org/obo/PR_000016043 T-cell acute lymphocytic leukemia protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/OBI_0002138 temperature value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specification that specifies the temperature of some thing. http://purl.obolibrary.org/obo/OBI_0002139 volume value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specification that specifies the volume of some thing. http://purl.obolibrary.org/obo/OBI_0002556 minimum age value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specifcation that specifies the youngest age when specifying an age range. http://purl.obolibrary.org/obo/OBI_0002557 maximum age value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specifcation that specifies the oldest age when specifying an age range. http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The head is the anterior-most division of the body [GO]. http://purl.obolibrary.org/obo/UBERON_0000079 male reproductive system http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system The organs associated with producing offspring in the gender that produces spermatozoa. http://purl.obolibrary.org/obo/UBERON_0000403 scalp http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure The outer covering of the calvaria. It is composed of several layers: SKIN; subcutaneous connective tissue; the occipitofrontal muscle which includes the tendonous galea aponeurotica; Loose connective tissue; and the pericranium (the PERIOSTEUM of the SKULL). http://purl.obolibrary.org/obo/UBERON_0000474 female reproductive system http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system The organs and associated structures associated with bearing offspring in a female animal. http://purl.obolibrary.org/obo/UBERON_0000915 thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Subdivision of trunk that lies between the head and the abdomen. http://purl.obolibrary.org/obo/UBERON_0000991 gonad http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ Reproductive organ that produces and releases eggs (ovary) or sperm (testis). http://purl.obolibrary.org/obo/UBERON_0001003 skin epidermis http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outer epithelial layer of the skin that is superficial to the dermis. http://purl.obolibrary.org/obo/UBERON_0001007 digestive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. http://purl.obolibrary.org/obo/UBERON_0001008 renal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The renal system in an anatomical system that maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products.. http://purl.obolibrary.org/obo/UBERON_0001173 biliary tree http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A complex network of conduits that begins with the canals of Hering (intralobar bile duct) and progressively merges into a system of interlobular, septal, and major ducts which then coalesce to form the extrahepatic bile ducts, which finally deliver bile to the intestine, and in some species to the gallbladder. http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel Any of the tubular branching vessels that carry blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/UBERON_0001987 placenta http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell. http://purl.obolibrary.org/obo/UBERON_0002067 dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure the soft tissue that fills the cavities of bones http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. http://purl.obolibrary.org/obo/UBERON_0002390 hematopoietic system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Anatomical system that is involved in the production of hematopoietic cells. http://purl.obolibrary.org/obo/UBERON_0002495 long bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Long bone is a limb bone that is subcylindrical and has a shaft with periosteum separating the ends of the bones. Long bones are present only in the limbs[VSAO:wd]. http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages within the liver for the conveyance of bile. Includes right and left hepatic ducts even though these may join outside the liver to form the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0007798 vascular system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of all blood and lymph vessels. http://purl.obolibrary.org/obo/BFO_0000002 continuant http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that has temporal parts and that happens, unfolds or develops through time. http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n > 1 independent continuants c1, … cn which are not spatial regions are such that for all 1 i < j n, ci and cj share no common parts, are such that for each 1 i n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004]) http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. http://purl.obolibrary.org/obo/BFO_0000035 process boundary http://purl.obolibrary.org/obo/BFO_0000003 occurrent p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001]) http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. http://purl.obolibrary.org/obo/CLO_0000001 cell line cell http://purl.obolibrary.org/obo/OBI_0001866 secondary cultured cell A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture http://purl.obolibrary.org/obo/CLO_0000031 cell line http://purl.obolibrary.org/obo/OBI_0001905 secondary cultured cell population A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture). http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label http://purl.obolibrary.org/obo/IAO_0000009 datum label A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure. http://purl.obolibrary.org/obo/IAO_0000007 action specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity a directive information entity that describes an action the bearer will take http://purl.obolibrary.org/obo/IAO_0000009 datum label http://purl.obolibrary.org/obo/IAO_0000030 information content entity A label is a symbol that is part of some other datum and is used to either partially define the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant an information content entity is an entity that is generically dependent on some artifact and stands in relation of aboutness to some entity http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum a scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label. http://purl.obolibrary.org/obo/IAO_0000033 directive information entity http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity whose concretizations indicate to their bearer how to realize them in a process. http://purl.obolibrary.org/obo/IAO_0000038 graph http://purl.obolibrary.org/obo/IAO_0000309 diagram A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way. http://purl.obolibrary.org/obo/IAO_0000064 algorithm http://purl.obolibrary.org/obo/IAO_0000104 plan specification A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata. http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data item data about an ontology part is a data item about a part of an ontology, for example a term http://purl.obolibrary.org/obo/IAO_0000104 plan specification http://purl.obolibrary.org/obo/IAO_0000033 directive information entity A directive information entity with action specifications and objective specifications as parts that, when concretized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified. http://purl.obolibrary.org/obo/IAO_0000109 measurement datum http://purl.obolibrary.org/obo/IAO_0000027 data item A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device. http://purl.obolibrary.org/obo/IAO_0000178 material information bearer http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity in which a concretization of an information content entity inheres. http://purl.obolibrary.org/obo/IAO_0000308 figure http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something. http://purl.obolibrary.org/obo/IAO_0000309 diagram http://purl.obolibrary.org/obo/IAO_0000308 figure A figure that expresses one or more propositions http://purl.obolibrary.org/obo/IAO_0000310 document http://purl.obolibrary.org/obo/IAO_0000030 information content entity A collection of information content entities intended to be understood together as a whole http://purl.obolibrary.org/obo/IAO_0000408 length measurement datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A scalar measurement datum that is the result of measurement of length quality http://purl.obolibrary.org/obo/IAO_0000414 mass measurement datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A scalar measurement datum that is the result of measurement of mass quality http://purl.obolibrary.org/obo/IAO_0000416 time measurement datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A scalar measurement datum that is the result of measuring a temporal interval http://purl.obolibrary.org/obo/IAO_0000572 documenting http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process in which a document is created or added to by including the specified input in it. http://purl.obolibrary.org/obo/OBI_0000010 fluorescent reporter intensity http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum that represents the output of a scanner measuring the intensity value for each fluorescent reporter. http://purl.obolibrary.org/obo/OBI_0000011 planned process http://purl.obolibrary.org/obo/BFO_0000015 process A processual entity that realizes a plan which is the concretization of a plan specification. http://purl.obolibrary.org/obo/OBI_0000047 processed material http://purl.obolibrary.org/obo/BFO_0000040 material entity Is a material entity that is created or changed during material processing. http://purl.obolibrary.org/obo/OBI_0000054 ratio of collected to emitted light http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum measuring the amount of light collected s compared to the total amount of emitted light in the detector component of a flow cytometer instrument. The datum has a qualitative role http://purl.obolibrary.org/obo/OBI_0000066 investigation http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s). http://purl.obolibrary.org/obo/OBI_0000067 evaluant role http://purl.obolibrary.org/obo/BFO_0000023 role a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role http://purl.obolibrary.org/obo/OBI_0000079 culture medium http://purl.obolibrary.org/obo/OBI_0000047 processed material a processed material that provides the needed nourishment for microorganisms or cells grown in vitro. http://purl.obolibrary.org/obo/OBI_0000101 measured expression level http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum that is the outcome of the quantification of an assay for the activity of a gene, or the number of RNA transcripts. http://purl.obolibrary.org/obo/OBI_0000112 specimen role http://purl.obolibrary.org/obo/BFO_0000023 role a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation http://purl.obolibrary.org/obo/OBI_0000119 number of particles in subset http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum measuring the number of subjects in a defined subset in a flow cytometer instrument. The datum has a qualitative role http://purl.obolibrary.org/obo/OBI_0000125 number of lost events electronic http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum measuring the number of analysis events lost due to errors in data acquisition electronic coincidence in a flow cytometer instrument. The datum has a qualitative role. http://purl.obolibrary.org/obo/OBI_0000172 parameter threshold http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum measuring the minimal signal that must be detected to generate an electrical event, as compared to the maximal detected signal in a flow cytometer instrument. The datum has a qualitative role http://purl.obolibrary.org/obo/OBI_0000269 number of lost events computer http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum recording the number of measurement events lost due to overloading of the analysis chip in a flow cytometer instrument. The datum has a qualitative role http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/IAO_0000104 plan specification A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process. http://purl.obolibrary.org/obo/OBI_0000275 analyte role http://purl.obolibrary.org/obo/OBI_0002444 measurand role A measurand role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role. http://purl.obolibrary.org/obo/OBI_0000319 material to be added role http://purl.obolibrary.org/obo/BFO_0000023 role material to be added role is a protocol participant role realized by a material which is added into a material bearing the target of material addition role in a material addition process http://purl.obolibrary.org/obo/OBI_0000338 drawing a conclusion based on data http://purl.obolibrary.org/obo/OBI_0000011 planned process A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion http://purl.obolibrary.org/obo/OBI_0000339 planning http://purl.obolibrary.org/obo/BFO_0000015 process a process of creating or modifying a plan specification http://purl.obolibrary.org/obo/OBI_0000437 analyte measurement objective http://purl.obolibrary.org/obo/OBI_0000441 assay objective an assay objective to determine the presence or concentration of an analyte in the evaluant http://purl.obolibrary.org/obo/OBI_0000441 assay objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role) http://purl.obolibrary.org/obo/OBI_0000443 analyte assay http://purl.obolibrary.org/obo/OBI_0000070 assay An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant. http://purl.obolibrary.org/obo/OBI_0000453 measure function http://purl.obolibrary.org/obo/BFO_0000034 function Measure function is a function that is borne by a processed material and realized in a process in which information about some entity is expressed relative to some reference. http://purl.obolibrary.org/obo/OBI_0000455 consume data function http://purl.obolibrary.org/obo/BFO_0000034 function Process data function is a function that is borne by in a material entity by virtue of its structure. When realized the material entity consumes data. http://purl.obolibrary.org/obo/OBI_0000471 study design execution http://purl.obolibrary.org/obo/OBI_0000011 planned process a planned process that carries out a study design http://purl.obolibrary.org/obo/OBI_0000639 material separation objective http://purl.obolibrary.org/obo/OBI_0000456 material transformation objective is an objective to transform a material entity into spatially separated components. http://purl.obolibrary.org/obo/OBI_0000678 portioning objective http://purl.obolibrary.org/obo/OBI_0000639 material separation objective A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material. http://purl.obolibrary.org/obo/OBI_0000681 separation into different composition objective http://purl.obolibrary.org/obo/OBI_0000639 material separation objective A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities). http://purl.obolibrary.org/obo/OBI_0000684 specimen collection objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification A objective specification to obtain a material entity for potential use as an input during an investigation. http://purl.obolibrary.org/obo/OBI_0000789 survival rate http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement data that represents the percentage of people or animals in a study or treatment group who are alive for a given period of time after diagnosis or initiation of monitoring. http://purl.obolibrary.org/obo/OBI_0000806 material maintenance objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification An objective specification maintains some or all of the qualities of a material over time. http://purl.obolibrary.org/obo/OBI_0000811 primary structure of DNA macromolecule http://purl.obolibrary.org/obo/SO_0000001 region a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues. http://purl.obolibrary.org/obo/OBI_0000838 material maintenance http://purl.obolibrary.org/obo/OBI_0000011 planned process a process with that achieves the objective to maintain some or all of the characteristics of an input material over time http://purl.obolibrary.org/obo/OBI_0000953 processed specimen http://purl.obolibrary.org/obo/OBI_0100051 specimen A specimen that has been intentionally physically modified. http://purl.obolibrary.org/obo/OBI_0000963 categorical label http://purl.obolibrary.org/obo/IAO_0000009 datum label A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale. http://purl.obolibrary.org/obo/OBI_0000973 sequence data http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement. http://purl.obolibrary.org/obo/OBI_0000976 handedness categorical measurement datum http://purl.obolibrary.org/obo/OBI_0000938 categorical measurement datum A datum used to record the answer to a self assessment of whether a person uses their left hand, right hand primarily or each hand equally http://purl.obolibrary.org/obo/OBI_0000984 dose http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses. http://purl.obolibrary.org/obo/OBI_0000991 Edinburgh score http://purl.obolibrary.org/obo/OBI_0000970 scalar score from composite inputs A score that measures the dominance of a person's right or left hand in everyday activities. http://purl.obolibrary.org/obo/OBI_0001000 questionnaire http://purl.obolibrary.org/obo/IAO_0000310 document A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study. http://purl.obolibrary.org/obo/OBI_0001001 Edinburgh handedness assay http://purl.obolibrary.org/obo/OBI_0000944 handedness assay The Edinburgh Handedness assay is an assay in which a set of questions = the Edinburgh Handedness inventory - is asked and the answers to these questions are turned into a score, used to assess the dominance of a person's right or left hand in everyday activities. The inventory can be used by an observer assessing the person, or by a person self-reporting hand use. The latter method tends to be less reliable due to a person over-attributing tasks to the dominant hand. http://purl.obolibrary.org/obo/OBI_0001144 binding constant http://purl.obolibrary.org/obo/OBI_0001181 binding datum A binding datum about the disposition of two or more material entities to form complexes which comes in the form of a scalar and unit that are utilized in equations that model the binding process http://purl.obolibrary.org/obo/OBI_0001155 3D structural organization datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum that describes the structural orientation of a material entity in 3D space. http://purl.obolibrary.org/obo/OBI_0001156 age since planting measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing. http://purl.obolibrary.org/obo/OBI_0001157 age since hatching measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg. http://purl.obolibrary.org/obo/OBI_0001158 age measurement assay http://purl.obolibrary.org/obo/OBI_0000070 assay An assay that measures the duration of temporal interval of a process that is part of the life of the bearer, where the initial time point of the measured process is the beginning of some transitional state of the bearer such as birth or when planted. http://purl.obolibrary.org/obo/OBI_0001159 age since egg laying measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism. http://purl.obolibrary.org/obo/OBI_0001161 age since germination measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth. http://purl.obolibrary.org/obo/OBI_0001163 age since eclosion measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon. http://purl.obolibrary.org/obo/OBI_0001164 age since sowing measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination. http://purl.obolibrary.org/obo/OBI_0001165 age since coitus measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction. http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum http://purl.obolibrary.org/obo/IAO_0000416 time measurement datum A time measurement datum that is the result of measurement of age of an organism http://purl.obolibrary.org/obo/OBI_0001168 age since fertilization measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. http://purl.obolibrary.org/obo/OBI_0001169 age since birth measurement datum http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother. http://purl.obolibrary.org/obo/OBI_0001172 dose response curve http://purl.obolibrary.org/obo/IAO_0000573 line graph A data item of paired values, one indicating the dose of a material, the other quantitating a measured effect at that dose. The dosing intervals are chosen so that effect values be interpolated by a plotting a curve. http://purl.obolibrary.org/obo/OBI_0001180 half maximal effective concentration (EC50) http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time. http://purl.obolibrary.org/obo/OBI_0001181 binding datum http://purl.obolibrary.org/obo/IAO_0000027 data item A data item that states if two or more material entities have the disposition to form a complex, and if so, how strong that disposition is. http://purl.obolibrary.org/obo/OBI_0001191 half maximal inhibitory concentration (IC50) http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum Half maximal inhibitory concentration (IC50) is a scalar measurement datum that measures the effectiveness of a compound to competitively inhibit a given process, and corresponds to the concentration of the compound at which it reaches half of its maximum inhibitory effect. http://purl.obolibrary.org/obo/OBI_0001514 minimal inhibitory concentration http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A scalar measurement datum that indicates the lowest concentration at which a specific compound significantly inhibits a process from occurring compared to in the absence of the compound. http://purl.obolibrary.org/obo/OBI_0001522 sequence assembly algorithm http://purl.obolibrary.org/obo/IAO_0000064 algorithm An algorithm used to assemble individual sequence reads into larger contiguous sequences (contigs). Assembly details include but are not limited to assembler type (overlap-layout-consensus, deBruijn), assembler version, and any relevant quality control information such as per cent known genes/ESTs captured. http://purl.obolibrary.org/obo/OBI_0001525 PDB file http://purl.obolibrary.org/obo/OBI_0001155 3D structural organization datum A 3d structural organization datum capturing the results of X-ray crystallography or NMR experiment that is formatted as specified by the Protein Databank (http://www.wwpdb.org/docs.html). A PDB file can describe the structure of multiple molecules, each of which has a different chain identifier assigned. http://purl.obolibrary.org/obo/OBI_0001536 equilibrium dissociation constant (KD) http://purl.obolibrary.org/obo/OBI_0001144 binding constant A binding constant defined as the ratio of kon over koff (on-rate of binding divided by off-rate) http://purl.obolibrary.org/obo/OBI_0001548 equilibrium association constant (KA) http://purl.obolibrary.org/obo/OBI_0001144 binding constant A binding constant defined as the ratio of koff over kon (off-rate of binding divided by on-rate) http://purl.obolibrary.org/obo/OBI_0001554 rate measurement datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A scalar measurement datum that represents the number of events occuring over a time interval http://purl.obolibrary.org/obo/OBI_0001571 equilibrium dissociation constant (KD) approximated by IC50 http://purl.obolibrary.org/obo/OBI_0001191 half maximal inhibitory concentration (IC50) A measurement of an IC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, there is a single population of sites on the receptor that competitor and ligand are binding to, and the concentration of the receptor must be much less than the KD for the competitor and the ligand. In this case, according to Cheng and Prussoff, KD = IC50 / (1 + Lstot / KDs), in which Lstot is the total concentration of the labeled competitor and KDs is the KD value of that competitor. http://purl.obolibrary.org/obo/OBI_0001573 DNA sequence data http://purl.obolibrary.org/obo/OBI_0000973 sequence data A sequence data item that is about the primary structure of DNA http://purl.obolibrary.org/obo/OBI_0001581 equilibrium dissociation constant (KD) approximated by EC50 http://purl.obolibrary.org/obo/OBI_0001180 half maximal effective concentration (EC50) A measurement of an EC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, and the concentration of the receptor must be much less than the KD for the ligand. http://purl.obolibrary.org/obo/OBI_0001583 half life of binding datum http://purl.obolibrary.org/obo/OBI_0001171 half life datum (t 1/2) A half life datum of the time it takes for 50% of bound complexes in an ensemble to disassociate in absence of re-association. http://purl.obolibrary.org/obo/OBI_0001588 binding http://purl.obolibrary.org/obo/GO_0008150 biological_process The process of material entities forming complexes. http://purl.obolibrary.org/obo/OBI_0001596 PDB file chain http://purl.obolibrary.org/obo/OBI_0001155 3D structural organization datum A 3D structural organization datum that is part of a PDB file and has a specific chain identifier that identifies the entire information on a subset of the material entities http://purl.obolibrary.org/obo/OBI_0001603 binding off rate measurement datum (koff) http://purl.obolibrary.org/obo/OBI_0001554 rate measurement datum A rate measurement datum of how quickly bound complexes disassociate http://purl.obolibrary.org/obo/OBI_0001605 binding on rate measurement datum (kon) http://purl.obolibrary.org/obo/OBI_0001554 rate measurement datum A rate measurement datum of how quickly bound complexes form http://purl.obolibrary.org/obo/OBI_0001866 secondary cultured cell http://purl.obolibrary.org/obo/CL_0000010 cultured cell A cultured cell that has been passaged or derives from a cell that has been passaged in culture. http://purl.obolibrary.org/obo/OBI_0001867 establishing cell line http://purl.obolibrary.org/obo/OBI_0600036 establishing cell culture a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics (e.g. immortalization or some other stable genetic modification, or selection of some defined subset). http://purl.obolibrary.org/obo/OBI_0001872 sequence assembly process http://purl.obolibrary.org/obo/OBI_0200000 data transformation A data transformation that assembles two or more individual sequence reads into contiguous sequences (i.e., contigs). http://purl.obolibrary.org/obo/OBI_0001873 number of errors http://purl.obolibrary.org/obo/OBI_0001933 value specification a data item that is the number of times that a given process failed, as an integer http://purl.obolibrary.org/obo/OBI_0001874 random access memory size http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum random access memory size is a scalar measurement datum which denotes the amount of physical memory know as random access memory present of a computer or required by a computational process or data transformation http://purl.obolibrary.org/obo/OBI_0001879 reagent http://purl.obolibrary.org/obo/OBI_0000047 processed material A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output. http://purl.obolibrary.org/obo/OBI_0001909 conclusion based on data http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity that is inferred from data. http://purl.obolibrary.org/obo/OBI_0001912 cell freezing medium http://purl.obolibrary.org/obo/OBI_0000047 processed material A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles. http://purl.obolibrary.org/obo/OBI_0001929 mass value specification http://purl.obolibrary.org/obo/OBI_0001931 scalar value specification A value specification that specifies the mass of some thing. http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specification that is specifies one category out of a fixed number of nominal categories http://purl.obolibrary.org/obo/OBI_0001931 scalar value specification http://purl.obolibrary.org/obo/OBI_0001933 value specification A value specification that consists of two parts: a numeral and a unit label http://purl.obolibrary.org/obo/OBI_0001933 value specification http://purl.obolibrary.org/obo/IAO_0000030 information content entity An information content entity that specifies a value within a classification scheme or on a quantitative scale. http://purl.obolibrary.org/obo/OBI_0001939 genome coverage http://purl.obolibrary.org/obo/IAO_0000027 data item A data item that is the total number of bases in reads, divided by genome size, assumed to be the reference size (for instance of 3.10 Gb for human and 2.73 Gb for mouse) and refers to the percentage of the genome that is contained in the assembly based on size estimates; these are usually based on cytological techniques. Genome coverage of 90–95% is generally considered to be good, as most genomes contain a considerable fraction of repetitive regions that are difficult to sequence. So it is not a cause for concern if the genome coverage of an assembly is a bit less than 100%. http://purl.obolibrary.org/obo/OBI_0001941 contig N50 http://purl.obolibrary.org/obo/OBI_0001940 N50 N50 statistic computed for the contigs produced by the assembly process. A contig N50 is calculated by first ordering every contig by length from longest to shortest. Next, starting from the longest contig, the lengths of each contig are summed, until this running sum equals one-half of the total length of all contigs in the assembly. The contig N50 of the assembly is the length of the shortest contig in this list. http://purl.obolibrary.org/obo/OBI_0001945 scaffold N50 http://purl.obolibrary.org/obo/OBI_0001940 N50 N50 statistic computed for the scaffold produced by the assembly process. The method for computing the value is similar to that of contig N50 but uses scaffold information instead of contig information http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs. http://purl.obolibrary.org/obo/OBI_0100051 specimen http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity that has the specimen role. http://purl.obolibrary.org/obo/OBI_0200166 data transformation objective http://purl.obolibrary.org/obo/IAO_0000005 objective specification An objective specification to transformation input data into output data http://purl.obolibrary.org/obo/OBI_0400107 computer http://purl.obolibrary.org/obo/OBI_0000968 device A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions. http://purl.obolibrary.org/obo/OBI_0600014 material component separation http://purl.obolibrary.org/obo/OBI_0000094 material processing a material processing in which components of an input material become segregated in space http://purl.obolibrary.org/obo/OBI_0600024 maintaining cell culture http://purl.obolibrary.org/obo/OBI_0000838 material maintenance a protocol application in which cells are kept alive in a defined environment outside of an organism. part of cell_culturing http://purl.obolibrary.org/obo/OBI_0600036 establishing cell culture http://purl.obolibrary.org/obo/OBI_0000094 material processing a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line). http://purl.obolibrary.org/obo/PATO_0000011 age http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity A time quality inhering in a bearer by virtue of how long the bearer has existed. http://purl.obolibrary.org/obo/PATO_0000122 length http://purl.obolibrary.org/obo/BFO_0000019 quality A 1-D extent quality which is equal to the distance between two points. http://purl.obolibrary.org/obo/PATO_0000125 mass http://purl.obolibrary.org/obo/BFO_0000019 quality A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter. http://purl.obolibrary.org/obo/PATO_0000146 temperature http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity A physical quality of the thermal energy of a system. http://purl.obolibrary.org/obo/PATO_0000186 behavioral quality http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation. http://purl.obolibrary.org/obo/PATO_0000918 volume http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies. http://purl.obolibrary.org/obo/PATO_0001237 quality of a single physical entity http://purl.obolibrary.org/obo/BFO_0000019 quality A physical object quality which inheres in a single-bearer. http://purl.obolibrary.org/obo/PATO_0002201 handedness http://purl.obolibrary.org/obo/PATO_0000186 behavioral quality A behavioral quality inhering ina bearer by virtue of the bearer's unequal distribution of fine motor skill between its left and right hands or feet. http://purl.obolibrary.org/obo/PATO_0002202 left handedness http://purl.obolibrary.org/obo/PATO_0002201 handedness Handedness where the organism preferentially uses the left hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot. http://purl.obolibrary.org/obo/PATO_0002203 right handedness http://purl.obolibrary.org/obo/PATO_0002201 handedness Handedness where the organism preferentially uses the right hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot. http://purl.obolibrary.org/obo/PATO_0002204 ambidextrous handedness http://purl.obolibrary.org/obo/PATO_0002201 handedness Handedness where the organism exhibits no overall dominance in the use of right or left hand or foot in the performance of tasks that require one hand or foot or a dominant hand or foot. http://purl.obolibrary.org/obo/PR_000000001 protein http://purl.obolibrary.org/obo/PR_000018263 amino acid chain An amino acid chain that is produced de novo by ribosome-mediated translation of a genetically-encoded mRNA. http://purl.obolibrary.org/obo/PR_000001004 CD4 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence. http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. http://purl.obolibrary.org/obo/SO_0000148 supercontig http://purl.obolibrary.org/obo/SO_0000353 sequence_assembly One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's. http://purl.obolibrary.org/obo/SO_0000149 contig http://purl.obolibrary.org/obo/SO_0000353 sequence_assembly A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases. http://purl.obolibrary.org/obo/SO_0000353 sequence_assembly http://purl.obolibrary.org/obo/SO_0001248 assembly A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences. http://purl.obolibrary.org/obo/SO_0001248 assembly http://purl.obolibrary.org/obo/SO_0000001 region A region of the genome of known length that is composed by ordering and aligning two or more different regions. http://purl.obolibrary.org/obo/UO_0000001 length unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which is a standard measure of the distance between two points. http://purl.obolibrary.org/obo/UO_0000002 mass unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which is a standard measure of the amount of matter/energy of a physical object. http://purl.obolibrary.org/obo/UO_0000003 time unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which is a standard measure of the dimension in which events occur in sequence. http://purl.obolibrary.org/obo/UO_0000005 temperature unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which is a standard measure of the average kinetic energy of the particles in a sample of matter. http://purl.obolibrary.org/obo/UO_0000051 concentration unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which represents a standard measurement of how much of a given substance there is mixed with another substance. http://purl.obolibrary.org/obo/UO_0000095 volume unit http://purl.obolibrary.org/obo/IAO_0000003 measurement unit label A unit which is a standard measure of the amount of space occupied by any substance, whether solid, liquid, or gas. http://purl.obolibrary.org/obo/CHEBI_16991 deoxyribonucleic acid http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms. http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid. http://purl.obolibrary.org/obo/CL_0000000 cell type http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CL_0000010 cultured cell A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged. http://purl.obolibrary.org/obo/CL_0000003 native cell http://purl.obolibrary.org/obo/GO_0005623 cell A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment). http://purl.obolibrary.org/obo/CL_0000010 cultured cell http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro A cell in vitro that is or has been maintained or propagated as part of a cell culture. http://purl.obolibrary.org/obo/CL_0000021 female germ cell http://purl.obolibrary.org/obo/CL_0000586 germ cell Female germ cell is a germ cell that supports female gamete production. http://purl.obolibrary.org/obo/CL_0000031 neuroblast http://purl.obolibrary.org/obo/CL_0000055 non-terminally differentiated cell A cell that will develop into a neuron often after a migration phase. http://purl.obolibrary.org/obo/CL_0000034 stem cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell that self-renews as well as give rise to a single mature cell type. http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. http://purl.obolibrary.org/obo/CL_0000039 germ line cell http://purl.obolibrary.org/obo/CL_0000548 animal cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. http://purl.obolibrary.org/obo/CL_0000047 neuronal stem cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Neural stem cell is characterized as an undifferentiated cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple types of lineage-restricted progenitors. http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A stem cell that can give rise to multiple lineages of cells. http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell from which all cells of the body can form. http://purl.obolibrary.org/obo/CL_0000055 non-terminally differentiated cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A precursor cell with a limited number of potential fates. http://purl.obolibrary.org/obo/CL_0000056 myoblast http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. http://purl.obolibrary.org/obo/CL_0000066 epithelial cell http://purl.obolibrary.org/obo/CL_0000548 animal cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. http://purl.obolibrary.org/obo/CL_0000080 circulating cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. http://purl.obolibrary.org/obo/CL_0000098 sensory epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. http://purl.obolibrary.org/obo/CL_0000101 sensory neuron http://purl.obolibrary.org/obo/CL_0000526 afferent neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. http://purl.obolibrary.org/obo/CL_0000133 neurectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell Ectoderm destined to be nervous tissue. http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. http://purl.obolibrary.org/obo/CL_0000150 glandular epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A specialized epithelial cell that is capable of synthesizing and secreting certain biomolecules. http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell that specializes in controlled release of one or more substances. http://purl.obolibrary.org/obo/CL_0000152 exocrine cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct. http://purl.obolibrary.org/obo/CL_0000183 contractile cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell whose primary function is to shorten. http://purl.obolibrary.org/obo/CL_0000187 muscle cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle http://purl.obolibrary.org/obo/CL_0002371 somatic cell A somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/CL_0000206 chemoreceptor cell http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell A cell type found in the spherical or ovoid clusters of receptor cells found mainly in the epithelium of the tongue and constituting the end organs of the sense of taste. http://purl.obolibrary.org/obo/CL_0000211 electrically active cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell whose function is determined by the generation or the reception of an electric signal. http://purl.obolibrary.org/obo/CL_0000219 motile cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell that moves by its own activities. http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell A cell of the outer of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell A cell of the middle germ layer of the embryo. http://purl.obolibrary.org/obo/CL_0000223 endodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell A cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000307 tracheal epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell found in the trachea. http://purl.obolibrary.org/obo/CL_0000312 keratinocyte http://purl.obolibrary.org/obo/CL_0000362 epidermal cell An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell that is specialised to accumulate a particular substance(s). http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. http://purl.obolibrary.org/obo/CL_0000337 neuroblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000031 neuroblast An embryonic cell that develops into a nerve cell or neuron. http://purl.obolibrary.org/obo/CL_0000346 hair follicle dermal papilla cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A specialized mesenchymal cell that resides in the dermal papilla located at the bottom of hair follicles. This cell plays a pivotal roles in hair formation, growth, and cycling. http://purl.obolibrary.org/obo/CL_0000352 epiblast cell http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. http://purl.obolibrary.org/obo/CL_0000355 multi-potent skeletal muscle stem cell http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. http://purl.obolibrary.org/obo/CL_0000362 epidermal cell http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the integument (the outer layer of an organism). http://purl.obolibrary.org/obo/CL_0000393 electrically responsive cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell whose function is determined by its response to an electric signal. http://purl.obolibrary.org/obo/CL_0000404 electrically signaling cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell that initiates an electrical signal and passes that signal to another cell. http://purl.obolibrary.org/obo/CL_0000419 seam cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell An epithelial fate stem cell found in flatworms. http://purl.obolibrary.org/obo/CL_0000526 afferent neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron which conveys sensory information centrally from the periphery. http://purl.obolibrary.org/obo/CL_0000540 neuron http://purl.obolibrary.org/obo/CL_0002319 neural cell The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/CL_0000566 angioblastic mesenchymal cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell capable of developing into blood vessel endothelium. http://purl.obolibrary.org/obo/CL_0000578 experimentally modified cell in vitro http://purl.obolibrary.org/obo/CL_0001034 cell in vitro A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure. http://purl.obolibrary.org/obo/CL_0000586 germ cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell The reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell An elongated, spindle-shaped, cell that is located between the basal lamina and the plasmalemma of a muscle fiber. These cells are mostly quiescent, but upon activation they divide to produce cells that generate new muscle fibers. http://purl.obolibrary.org/obo/CL_0000646 basal cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell Undifferentiated; mitotic stem cell for other epithelial cell types; rounded or elliptical with little cytoplasm and few organelles; contain cytokeratin intermediate filament. http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A non-terminally differentiated cell that is capable of developing into a muscle cell. http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from neural plate and neural crest. http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A cell of a hematopoietic lineage. http://purl.obolibrary.org/obo/CL_0001008 Kit and Sca1-positive hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell A hematopoietic stem cell that has plasma membrane part Kit-positive, SCA-1-positive, CD150-positive and CD34-negative. http://purl.obolibrary.org/obo/CL_0001024 CD34-positive, CD38-negative hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. http://purl.obolibrary.org/obo/CL_0001034 cell in vitro http://purl.obolibrary.org/obo/GO_0005623 cell A cell that is maintained or propagated in a controlled artificial environment for use in an investigation. http://purl.obolibrary.org/obo/CL_0001035 bone cell http://purl.obolibrary.org/obo/CL_0000548 animal cell A connective tissue cell found in bone. http://purl.obolibrary.org/obo/CL_0002033 short term hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0001008 Kit and Sca1-positive hematopoietic stem cell A hematopoietic stem cell capable of rapid replenishment of myeloerythroid progenitors and limited self renewal capability. This cell is Kit-positive, Sca1-positive, CD34-positive, CD150-positive, and is Flt3-negative. http://purl.obolibrary.org/obo/CL_0002034 long term hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0001008 Kit and Sca1-positive hematopoietic stem cell A hematopoietic stem cell with long term self renewal capability. This cell is Kit-positive, Sca1-positive, CD150-positive, CD90-low, CD34-negative and Flt3-negative. http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell An epithelial cell derived from endoderm. http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell An epithelial cell derived from ectoderm. http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell Epithelial cell derived from mesoderm or mesenchyme. http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell http://purl.obolibrary.org/obo/CL_0001035 bone cell A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from general body ectoderm and ectoderm placodes. http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell found in the lining of the stomach. http://purl.obolibrary.org/obo/CL_0002180 mucous cell of stomach http://purl.obolibrary.org/obo/CL_0002659 glandular cell of stomach A mucous cell in the epithelium of the stomach. http://purl.obolibrary.org/obo/CL_0002183 stem cell of gastric gland http://purl.obolibrary.org/obo/CL_0002180 mucous cell of stomach A stomach epithelial cell that is olumnar in form with a few short apical microvilli; relatively undifferentiated mitotic cell from which other types of gland are derived; few in number, situated in the isthmus region of the gland and base of the gastric pit. http://purl.obolibrary.org/obo/CL_0002187 basal cell of epidermis http://purl.obolibrary.org/obo/CL_1000428 stem cell of epidermis A basally situated, mitotically active, columnar-shaped keratinocyte attached to the basement membrane. http://purl.obolibrary.org/obo/CL_0002195 hepatic stem cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A stem cell that can give rise to the cells of the liver. http://purl.obolibrary.org/obo/CL_0002196 hepatic oval stem cell http://purl.obolibrary.org/obo/CL_0002195 hepatic stem cell A transient hepatic stem cell observed after liver injury with a high nuclear to cytoplasm ratio that can differentiate into mature hepatocytes and bile duct cells. Arises from more than one tissue. http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract An epithelial cell of the tracheobronchial tree. http://purl.obolibrary.org/obo/CL_0002231 epithelial cell of prostate http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the prostate. http://purl.obolibrary.org/obo/CL_0002246 peripheral blood stem cell http://purl.obolibrary.org/obo/CL_0000080 circulating cell A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). http://purl.obolibrary.org/obo/CL_0002248 pluripotent stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A pluripotent stem cell has the ability to form cells from all three germ layers (ectoderm, mesoderm, and endoderm). However, unlike totipotent stem cells, they cell can not generate all the cells of the whole organism such as placenta. http://purl.obolibrary.org/obo/CL_0002249 primitive cardiac myocyte http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A stem cell that can differentiate into a cardiac myocyte. http://purl.obolibrary.org/obo/CL_0002250 intestinal crypt stem cell http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell A cell that is found in a zone occupying the bottom region of the crypt; provide the source of most of the cell types of the intestinal epithelium; proliferate by mitotic division; differentiates into columnar or goblet cells. http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/CL_0002259 neuroepithelial stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell The stem cell from which glial precursor cell arises from. http://purl.obolibrary.org/obo/CL_0002285 type III taste bud cell http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell A taste receptor cell that is characterized by morphologically identifiable synaptic contacts with the gustatory nerve fibers and expression of the synaptic membrane protein-25 (SNAP-25) and NCAM. http://purl.obolibrary.org/obo/CL_0002287 type IV taste receptor cell http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell A rounded, mitotically active stem cell which is the source of new cells of the taste bud; located basally. http://purl.obolibrary.org/obo/CL_0002319 neural cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A cell that is part of the nervous system. http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell A cell of the supporting or framework tissue of the body, arising chiefly from the embryonic mesoderm and including adipose tissue, cartilage, and bone. http://purl.obolibrary.org/obo/CL_0002321 embryonic cell http://purl.obolibrary.org/obo/CL_0000548 animal cell A cell of the embryo. http://purl.obolibrary.org/obo/CL_0002322 embryonic stem cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell A stem cell of embryonic origin. http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell of the bronchus. http://purl.obolibrary.org/obo/CL_0002329 basal epithelial cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell type that lacks the columnar shape typical for other respiratory epithelial cells. This cell type is able to differentiate into other respiratory epithelial cells in response to injury. http://purl.obolibrary.org/obo/CL_0002337 keratinocyte stem cell http://purl.obolibrary.org/obo/CL_0000312 keratinocyte A stem cell located in the bulge of the hair follicle that can give rise to regenerate the new follicle with each hair cycle and to reepithelialize the epidermis during wound repair. http://purl.obolibrary.org/obo/CL_0002339 prostate stem cell http://purl.obolibrary.org/obo/CL_0002341 basal cell of prostate epithelium A prostate epithelial cell that is CD133-positive, CD44-positive, integrin A2beta3-high. This cell is a stem cell for the prostate epithelium. http://purl.obolibrary.org/obo/CL_0002341 basal cell of prostate epithelium http://purl.obolibrary.org/obo/CL_0002231 epithelial cell of prostate An undifferentiated cell of the prostate epithelium that lacks secretory activity. http://purl.obolibrary.org/obo/CL_0002351 progenitor cell of endocrine pancreas http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A multi-fate stem cell that is able to differentiate into the pancreas alpha, beta and delta endocrine cells. This cell type expresses neurogenin-3 and Isl-1. http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell A hematopoietic stem cell that exists during embryogenesis. http://purl.obolibrary.org/obo/CL_0002353 fetal liver hematopoietic progenitor cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem cell that resides in the fetal liver. In mice, this cell type is first observed at E10.5. This cell type is MHC-positive, HSA-positive, AA4.1-positive, CD45-positive, Sca-1 positive, CD150-positive, CD48-negative and CD244-negative. http://purl.obolibrary.org/obo/CL_0002354 yolk sac hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem found in the yolk sac. In mice, this cell type is Sca-1-negative, CD45-negative, MHC-negative, HSA-positive, AA4.1-positive, CD44-positive. http://purl.obolibrary.org/obo/CL_0002359 placental hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem cell of the placenta. This cell type is first observed E10.5 This cell type may give rise to fetal liver hematopoietic stem cells. http://purl.obolibrary.org/obo/CL_0002360 AGM hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell A hematopoietic stem cell from the aorta-gonad-mesonephros region of the developing embryo. First seen at E10.5 in mouse embryos. May give rise to fetal liver HSC. http://purl.obolibrary.org/obo/CL_0002362 granule cell precursor http://purl.obolibrary.org/obo/CL_0000337 neuroblast (sensu Vertebrata) A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and NK1-positive. http://purl.obolibrary.org/obo/CL_0002368 respiratory epithelial cell http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An endo-epithelial cell of the respiratory tract. http://purl.obolibrary.org/obo/CL_0002371 somatic cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell of an organism that does not pass on its genetic material to the organism's offspring (i.e. a non-germ line cell). http://purl.obolibrary.org/obo/CL_0002451 mammary stem cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A multi-fate stem cell that is the source of cells for growth of the mammary gland during puberty and gestation. This cell type gives rise to both the luminal and myoepithelial cell types of the gland, and have been shown to have the ability to regenerate the entire organ in mice. This cell type also plays an important role in carcinogenesis of the breast. This cell type is Lin-, CD24-positive, CD29-hi. http://purl.obolibrary.org/obo/CL_0002537 amnion mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of the amnion membrane. http://purl.obolibrary.org/obo/CL_0002540 mesenchymal stem cell of the bone marrow http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell A mesenchymal stem cell that is part of the bone marrow. http://purl.obolibrary.org/obo/CL_0002541 chorionic membrane mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of the chorionic membrane. http://purl.obolibrary.org/obo/CL_0002563 intestinal epithelial cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell of the intestine. http://purl.obolibrary.org/obo/CL_0002568 mesenchymal stem cell of Wharton's jelly http://purl.obolibrary.org/obo/CL_0002569 mesenchymal stem cell of umbilical cord A mesenchymal stem cell that is part of Wharton's jelly. http://purl.obolibrary.org/obo/CL_0002569 mesenchymal stem cell of umbilical cord http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell A mesenchymal stem cell of the umbilical cord. http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of adipose tissue. http://purl.obolibrary.org/obo/CL_0002571 hepatic mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0002195 hepatic stem cell A mesenchymal stem cell of liver. http://purl.obolibrary.org/obo/CL_0002572 vertebral mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0001035 bone cell A mesenchymal stem cell of the vertebrae. http://purl.obolibrary.org/obo/CL_0002607 migratory enteric neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell A neural crest cell that gives rise to cells of the enteric nervous system. http://purl.obolibrary.org/obo/CL_0002619 adult endothelial progenitor cell http://purl.obolibrary.org/obo/CL_0000566 angioblastic mesenchymal cell An adult angioblastic cell released from the bone marrow, capable of blood circulation and participation in angiogenesis by differentiating into blood vessel endothelial cells. Their existence is controversial. http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell http://purl.obolibrary.org/obo/CL_0002368 respiratory epithelial cell A basal cell in the respiratory tract. http://purl.obolibrary.org/obo/CL_0002638 bronchioalveolar stem cell http://purl.obolibrary.org/obo/CL_1000351 basal cell of epithelium of respiratory bronchiole A respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole. This cell types gives rise to alveolar cell types and Clara cells in response to lung injury. This cell type expresses markers Scgb1a1 and Sftpc. http://purl.obolibrary.org/obo/CL_0002639 amniotic stem cell http://purl.obolibrary.org/obo/CL_0002323 amniocyte An amniotic stem cell is a mesenchymalstem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue type such as skin, cartilage, cardiac tissue, nerves, muscle, and bone http://purl.obolibrary.org/obo/CL_0002640 amniotic epithelial stem cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell An epithelial fate stem cell derived form the amnion membrane. http://purl.obolibrary.org/obo/CL_0002659 glandular cell of stomach http://purl.obolibrary.org/obo/CL_0002178 epithelial cell of stomach A glandular epithelial cell that is part of the stomach. http://purl.obolibrary.org/obo/CL_0002664 cardioblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. http://purl.obolibrary.org/obo/CL_0002672 retinal progenitor cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. http://purl.obolibrary.org/obo/CL_0002676 neural crest derived neuroblast http://purl.obolibrary.org/obo/CL_0000337 neuroblast (sensu Vertebrata) A neuroblast derived from a neural crest cell. http://purl.obolibrary.org/obo/CL_0005020 lymphangioblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell Lymphatic progenitor cells. http://purl.obolibrary.org/obo/CL_0005021 mesenchymal lymphangioblast http://purl.obolibrary.org/obo/CL_0005020 lymphangioblast Mesenchymal derived lymphatic progenitor cells that give rise to the superficial lymphatics. http://purl.obolibrary.org/obo/CL_0005022 vascular lymphangioblast http://purl.obolibrary.org/obo/CL_0005020 lymphangioblast Lymphatic progenitor cells, derived from the veins, that give rise to lymphatic endothelial cells. http://purl.obolibrary.org/obo/CL_0005026 hepatoblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell Multi fate stem cell that gives rise to to both hepatocytes and cholangiocytes as descendants. http://purl.obolibrary.org/obo/CL_0007004 premigratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. http://purl.obolibrary.org/obo/CL_1000348 basal cell of epithelium of trachea http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A basal cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/CL_1000349 basal cell of epithelium of bronchus http://purl.obolibrary.org/obo/CL_0002633 respiratory basal cell A basal cell found in the bronchus epithelium. http://purl.obolibrary.org/obo/CL_1000350 basal cell of epithelium of terminal bronchiole http://purl.obolibrary.org/obo/CL_1000352 basal cell of epithelium of lobular bronchiole A basal cell that is part of the epithelium of terminal bronchiole. http://purl.obolibrary.org/obo/CL_1000351 basal cell of epithelium of respiratory bronchiole http://purl.obolibrary.org/obo/CL_1000352 basal cell of epithelium of lobular bronchiole A basal cell that is part of the epithelium of respiratory bronchiole. http://purl.obolibrary.org/obo/CL_1000352 basal cell of epithelium of lobular bronchiole http://purl.obolibrary.org/obo/CL_1000349 basal cell of epithelium of bronchus A basal cell that is part of the epithelium of bronchiole. http://purl.obolibrary.org/obo/CL_1000428 stem cell of epidermis http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A somatic stem cell that is part of the epidermis. http://purl.obolibrary.org/obo/CL_1000447 epithelial cell of stratum germinativum of esophagus http://purl.obolibrary.org/obo/CL_0000646 basal cell A basal cell that is part of the epithelium of esophagus. http://purl.obolibrary.org/obo/CL_1000486 basal cell of urothelium http://purl.obolibrary.org/obo/CL_0000646 basal cell A basal cell that is part of the urothelium. http://purl.obolibrary.org/obo/CL_1001566 bronchioalveolar stem cells http://purl.obolibrary.org/obo/CL_0000034 stem cell a respiratory stem cell found at the junction of the terminal (conductive) bronchiole and the respiratory bronchiole, which gives rise to alveolar cell types and Clara cells in response to lung injury. http://purl.obolibrary.org/obo/DOID_4 disease http://purl.obolibrary.org/obo/BFO_0000016 disposition A disease is a disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism. http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. http://purl.obolibrary.org/obo/UBERON_0000065 respiratory tract http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts http://purl.obolibrary.org/obo/UBERON_0000160 intestine http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Segment of the alimentary canal extending from the stomach to the anus and, in humans and other mammals, consists of two segments, the small intestine and the large intestine. http://purl.obolibrary.org/obo/UBERON_0000178 blood http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure A fluid that is composed of blood plasma and erythrocytes. http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. http://purl.obolibrary.org/obo/UBERON_0000945 stomach http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0000948 heart http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. http://purl.obolibrary.org/obo/UBERON_0000949 endocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. http://purl.obolibrary.org/obo/UBERON_0000955 brain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs concerned with reproduction. http://purl.obolibrary.org/obo/UBERON_0000995 uterus http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct the female muscular organ of gestation in which the developing embryo or fetus is nourished until birth http://purl.obolibrary.org/obo/UBERON_0001004 respiratory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Functional system which consists of structures involved in respiration. http://purl.obolibrary.org/obo/UBERON_0001016 nervous system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. http://purl.obolibrary.org/obo/UBERON_0001017 central nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. http://purl.obolibrary.org/obo/UBERON_0001043 esophagus http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). http://purl.obolibrary.org/obo/UBERON_0001130 vertebral column http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of skeletal system that consists of all the vertebra and associated skeletal elements and joints in the body[modified from VSAO]. http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue Muscle tissue that consists primarily of skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0001558 lower respiratory tract http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified] http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]. http://purl.obolibrary.org/obo/UBERON_0002048 lung http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Respiration organ that develops as an oupocketing of the esophagus. http://purl.obolibrary.org/obo/UBERON_0002101 limb http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin A paired appendage that is evolved from a paired fin. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the girdle and its parts. http://purl.obolibrary.org/obo/UBERON_0002107 liver http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO]. http://purl.obolibrary.org/obo/UBERON_0002185 bronchus http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube the upper conducting airways of the lung; these airways arise from the terminus of the trachea http://purl.obolibrary.org/obo/UBERON_0002204 musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the muscular and skeletal systems. http://purl.obolibrary.org/obo/UBERON_0002330 exocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0002367 prostate gland http://purl.obolibrary.org/obo/UBERON_0010147 male accessory sex gland The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. http://purl.obolibrary.org/obo/UBERON_0002391 lymph http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system through lymph capillaries[WP]. http://purl.obolibrary.org/obo/UBERON_0002394 bile duct http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Any of the ducts that form the biliary tree, carrying bile from the liver to the small intestine. http://purl.obolibrary.org/obo/UBERON_0002405 immune system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. http://purl.obolibrary.org/obo/UBERON_0002416 integumental system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. http://purl.obolibrary.org/obo/UBERON_0003126 trachea http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]. http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An organ involved in reproduction http://purl.obolibrary.org/obo/UBERON_0003703 extrahepatic bile duct http://purl.obolibrary.org/obo/UBERON_0002394 bile duct Passages external to the liver for the conveyance of bile. These include the common bile duct and the common hepatic duct. http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the heart and blood vessels. http://purl.obolibrary.org/obo/UBERON_0005409 alimentary part of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The part of the digestive system that excludes the hepatobiliary system. http://purl.obolibrary.org/obo/UBERON_0006558 lymphatic part of lymphoid system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision An organ system subdivision that is a network of vessels capable of removing accumulating protein and fluid from the interstitial space and returning it to the vascular space. In some species, this network is connected to the immune system via lymph nodes and lymphocyte-producing organs, with the whole being the lymphoid system. http://purl.obolibrary.org/obo/UBERON_0006562 pharynx http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. http://purl.obolibrary.org/obo/OGG_0000000001 genome http://purl.obolibrary.org/obo/BFO_0000040 material entity A genome is a material entity that represents the entirety of an organism's hereditary information. The genome includes both the genes and the non-coding sequences of the DNA and RNA. http://purl.obolibrary.org/obo/OGG_0000000002 gene http://purl.obolibrary.org/obo/BFO_0000040 material entity A gene is a material entity that represents the entire DNA sequence required for synthesis of a functional protein or RNA molecule. http://purl.obolibrary.org/obo/OGG_0000000003 gene disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition a disposition that a gene can be used as a blueprint for generating a new form of product such as protein. http://purl.obolibrary.org/obo/OGG_0000000010 protein-coding gene disposition http://purl.obolibrary.org/obo/OGG_0000000003 gene disposition a gene disposition that a gene can be used as a blueprint for generating a protein (i.e., a gene encodes for a protein). http://purl.obolibrary.org/obo/OGG_0000000025 pseudo gene disposition http://purl.obolibrary.org/obo/OGG_0000000003 gene disposition a gene disposition that represents the disposition of gene being "pseudo", i.e., the gene is a pseudogene. http://purl.obolibrary.org/obo/OGG_1000002759 genome of Eukaryota http://purl.obolibrary.org/obo/OGG_0000000001 genome The genome of an organism of Eukaryota http://purl.obolibrary.org/obo/OGG_1000009606 genome of Homo sapiens http://purl.obolibrary.org/obo/OGG_1000002759 genome of Eukaryota The genome of an organism of Homo sapiens http://purl.obolibrary.org/obo/OGG_2000002759 gene of Eukaryota http://purl.obolibrary.org/obo/OGG_0000000002 gene A gene of an organism of Eukaryota http://purl.obolibrary.org/obo/OGG_2000009606 gene of Homo sapiens http://purl.obolibrary.org/obo/OGG_2000002759 gene of Eukaryota A gene of an organism of Homo sapiens http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens http://purl.obolibrary.org/obo/OGG_2000009606 gene of Homo sapiens A gene of Homo sapiens that has a protein-coding gene disposition http://purl.obolibrary.org/obo/OGG_2070009606 pseudo gene of Homo sapiens http://purl.obolibrary.org/obo/OGG_2000009606 gene of Homo sapiens A gene of Homo sapiens that has a pseudo gene disposition http://purl.obolibrary.org/obo/UBERON_0000025 tube http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. http://purl.obolibrary.org/obo/UBERON_0000026 appendage http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Major subdivision of an organism that protrudes from the body[DOS, CARO]. http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions. http://purl.obolibrary.org/obo/UBERON_0000055 vessel http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular structure that contains, conveys body fluid, such as blood or lymph. http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A tubular structure that transports secreted or excreted substances. http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. http://purl.obolibrary.org/obo/UBERON_0000062 organ http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that performs a specific function or group of functions [WP]. http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity. http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A multicellular structure that is a part of an organ. http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube An section of a respiratory tract. http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. http://purl.obolibrary.org/obo/UBERON_0000076 external ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. http://purl.obolibrary.org/obo/UBERON_0000077 mixed endoderm/mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure An anatomical structure that develops from the endoderm and the mesoderm. http://purl.obolibrary.org/obo/UBERON_0000085 morula http://purl.obolibrary.org/obo/UBERON_0000922 embryo A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/UBERON_0000087 inner cell mass http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A mass of cells that develop into the body of the embryo and some extraembryonic tissues http://purl.obolibrary.org/obo/UBERON_0000088 trophoblast http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure the mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta http://purl.obolibrary.org/obo/UBERON_0000091 bilaminar disc http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. http://purl.obolibrary.org/obo/UBERON_0000095 cardiac neural crest http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia] http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium The epithelial layer of the lung. http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A tube in the respiratory system. Examples: bronchus, bronchiole, trachea. http://purl.obolibrary.org/obo/UBERON_0000118 lung bud http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium Structure derived from foregut that becomes a lung[GO]. http://purl.obolibrary.org/obo/UBERON_0000162 cloaca http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures http://purl.obolibrary.org/obo/UBERON_0000163 embryonic cloaca http://purl.obolibrary.org/obo/UBERON_0000162 cloaca endoderm-lined chamber that develops as pouch-like dilation of the caudal end of the hindgut and receives the allantois ventrally and two mesonephric ducts laterally; caudally it ends blindly at the cloacal membrane formed by the union of proctodeal (anal pit) ectoderm and cloacal endoderm, with no intervening mesoderm[MP]. http://purl.obolibrary.org/obo/UBERON_0000164 primitive urogenital sinus http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure the ventral part of the cloaca remaining after septation of the rectum, which further develops into part of the bladder, part of the prostatic part of the male urethra and the urethra and vestibule in females http://purl.obolibrary.org/obo/UBERON_0000170 pair of lungs http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection The pair of anatomical structures comprised of a left lung and right lung. http://purl.obolibrary.org/obo/UBERON_0000171 respiration organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/UBERON_0000173 amniotic fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid. http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. http://purl.obolibrary.org/obo/UBERON_0000305 amnion http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure the thin innermost layer of the extraembryonic membranes that contains the amniotic fluid; the membrane forms a closed sac in which the embryo and later, the fetus, is suspended and protected http://purl.obolibrary.org/obo/UBERON_0000307 blastula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000323 late embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo An embryo that is at the late embryonic stage; this stage covers late steps of the embryogenesis with a fully formed embryo still developing before birth or egg hatching. http://purl.obolibrary.org/obo/UBERON_0000325 gastric gland http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut The branched tubular glands found in the mucosa of the fundus and body of the stomach which contain parietal cells that secrete hydrochloric acid and zymogenic cells that produce pepsin. http://purl.obolibrary.org/obo/UBERON_0000328 gut wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity). http://purl.obolibrary.org/obo/UBERON_0000333 intestinal gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of the intestinal mucosa. Examples include the intestinal crypts, duodenal gland[cjm]. http://purl.obolibrary.org/obo/UBERON_0000344 mucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP] http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma http://purl.obolibrary.org/obo/UBERON_0000064 organ part functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. http://purl.obolibrary.org/obo/UBERON_0000358 blastocyst http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]. http://purl.obolibrary.org/obo/UBERON_0000365 urothelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelial tissue layer that lines much of the urinary tract, including the renal pelvis, the ureters, the bladder, and parts of the urethra. http://purl.obolibrary.org/obo/UBERON_0000376 hindlimb stylopod http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment The part of the hindlimb between pelvis and the knee, corresponding to the femur. http://purl.obolibrary.org/obo/UBERON_0000379 tracheal mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a respiratory airway. http://purl.obolibrary.org/obo/UBERON_0000383 musculature of body http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. http://purl.obolibrary.org/obo/UBERON_0000410 bronchial mucosa http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A mucosa that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000412 dermal papilla http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A mesodermal signaling center of the hair follicle consisting of closely packed specialized mesenchymal fibroblasts. Framed by the enlarged bulb matrix in anagen. http://purl.obolibrary.org/obo/UBERON_0000463 organism substance http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has mass. http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has no mass. http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that is an individual member of a species and consists of more than one cell. http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical group that has its parts adjacent to one another. http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA] http://purl.obolibrary.org/obo/UBERON_0000486 multilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA] http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA] http://purl.obolibrary.org/obo/UBERON_0000913 interstitial fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Interstitial fluid is a bodily fluid consisting of a solution which bathes and surrounds the cells of multicellular animals. It is the main component of the extracellular fluid, which also includes plasma and transcellular fluid. http://purl.obolibrary.org/obo/UBERON_0000916 abdomen http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0000922 embryo http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/UBERON_0000923 germ layer http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. http://purl.obolibrary.org/obo/UBERON_0000925 endoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. http://purl.obolibrary.org/obo/UBERON_0000926 mesoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer The middle germ layer of the embryo, between the endoderm and ectoderm. http://purl.obolibrary.org/obo/UBERON_0000978 leg http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment The portion of the hindlimb that contains both the stylopod and zeugopod. http://purl.obolibrary.org/obo/UBERON_0000981 femur http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element Endochondral longbone connecting the pelvic girdle with posterior zeugopodium skeleton.[VSAO, modified]. http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint http://purl.obolibrary.org/obo/UBERON_0004905 articulation Anatomical cluster that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. http://purl.obolibrary.org/obo/UBERON_0000993 oviduct http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A tube or collection of tubes in an animal from the ovaries to the outside of the body. http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway http://purl.obolibrary.org/obo/UBERON_0003103 compound organ An airway through which respiratory air passes in organisms. http://purl.obolibrary.org/obo/UBERON_0001009 circulatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Portion of connective tissue composed of adipocytes enmeshed in areolar tissue http://purl.obolibrary.org/obo/UBERON_0001015 musculature http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A subdivision of the muscular system corresponding to a subdisivision of an organism. http://purl.obolibrary.org/obo/UBERON_0001040 yolk sac http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. http://purl.obolibrary.org/obo/UBERON_0001041 foregut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Anterior subdivision of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0001045 midgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Middle subdivision of a digestive tract[CJM]. In vertebrates: The middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine[GO]. http://purl.obolibrary.org/obo/UBERON_0001046 hindgut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The caudalmost subdivision of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. http://purl.obolibrary.org/obo/UBERON_0001049 neural tube http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/UBERON_0001084 skin of head http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin A zone of skin that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001096 wall of esophagus http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001167 wall of stomach http://purl.obolibrary.org/obo/UBERON_0000328 gut wall the layered structure that makes up the stomach, typiclly consists of a serous coat, a muscular coat, a mucous membrane, and other tissue layers in between http://purl.obolibrary.org/obo/UBERON_0001171 portal lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The triangular region on the periphery of the liver lobules that contain a bile duct and a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel. http://purl.obolibrary.org/obo/UBERON_0001172 hepatic acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The functional unit of the liver, consisting of a mass of hepatocytes from adjacent liver lobules aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids. http://purl.obolibrary.org/obo/UBERON_0001193 hepatic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the liver. http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa The mucosal layer that lines the stomach. http://purl.obolibrary.org/obo/UBERON_0001242 intestinal mucosa http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa Mucosal layer that lines the intestine. http://purl.obolibrary.org/obo/UBERON_0001246 interlobular bile duct http://purl.obolibrary.org/obo/UBERON_0003704 intrahepatic bile duct The canals that carry bile in the liver between the intralobular ducts and the biliary ductules; interlobular bile ducts are part of the interlobular portal triad. http://purl.obolibrary.org/obo/UBERON_0001262 wall of intestine http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a intestine [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001271 pelvic girdle region http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The organism subdivision that includes the pelvic girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. http://purl.obolibrary.org/obo/UBERON_0001276 epithelium of stomach http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium The epithelial layer of the stomach . http://purl.obolibrary.org/obo/UBERON_0001277 intestinal epithelium http://purl.obolibrary.org/obo/UBERON_0004808 gastrointestinal system epithelium Epithelial layer that lines the intestine. http://purl.obolibrary.org/obo/UBERON_0001279 portal triad http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A multi-organ-part structure that consists of three vessels of the portal lobule including the bile duct, a terminal branch of the hepatic artery and portal vein, and may also include a lymphatic vessel http://purl.obolibrary.org/obo/UBERON_0001280 liver parenchyma http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure The functional units of the liver including the lobules. http://purl.obolibrary.org/obo/UBERON_0001282 intralobular bile duct http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct the tubules located between the bile canaliculi and interlobular bile ducts near the outer edge of a classic liver lobule http://purl.obolibrary.org/obo/UBERON_0001353 anal region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anus and surrounding regions. Encompasses both internal and external regions, where present http://purl.obolibrary.org/obo/UBERON_0001434 skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. http://purl.obolibrary.org/obo/UBERON_0001441 hindlimb skeleton http://purl.obolibrary.org/obo/UBERON_0007273 pelvic appendage skeleton Subdivision of skeleton consisting of all skeletal elements in an hindlimb region. http://purl.obolibrary.org/obo/UBERON_0001464 hip http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The hip region is located lateral to the gluteal region (i.e. the buttock), inferior to the iliac crest, and overlying the greater trochanter of the thigh bone. In adults, three of the bones of the pelvis have fused into the hip bone which forms part of the hip region. The hip joint, scientifically referred to as the acetabulofemoral joint (art. coxae), is the joint between the femur and acetabulum of the pelvis and its primary function is to support the weight of the body in both static (e.g. standing) and dynamic (e.g. walking or running) postures. [WP,modified]. http://purl.obolibrary.org/obo/UBERON_0001474 bone element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of bone tissue. http://purl.obolibrary.org/obo/UBERON_0001555 digestive tract http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. http://purl.obolibrary.org/obo/UBERON_0001890 forebrain http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The most anterior region the brain including both the telencephalon and diencephalon. http://purl.obolibrary.org/obo/UBERON_0001901 epithelium of trachea http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium the epithelial lining of the trachea which contains numerous ciliated cells http://purl.obolibrary.org/obo/UBERON_0001955 epithelium of respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0002051 epithelium of bronchiole An epithelium that is part of a respiratory bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001958 terminal bronchiole epithelium http://purl.obolibrary.org/obo/UBERON_0002051 epithelium of bronchiole An epithelium that lines a terminal bronchiole. http://purl.obolibrary.org/obo/UBERON_0001969 blood plasma http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid The liquid component of blood, in which erythrocytes are suspended. http://purl.obolibrary.org/obo/UBERON_0001976 epithelium of esophagus http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium the epithelial layer that lines the luminal space of the esophagus http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A vessel through which blood circulates in the body. http://purl.obolibrary.org/obo/UBERON_0001983 crypt of Lieberkuhn http://purl.obolibrary.org/obo/UBERON_0000333 intestinal gland the tubular intestinal glands found in the mucosal membranes http://purl.obolibrary.org/obo/UBERON_0001992 papillary layer of dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The upper layer of the dermis beneath the epidermis, composed of dense irregular connective tissue[ncit,modified]. http://purl.obolibrary.org/obo/UBERON_0002017 portal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that conducts blood from the digestive organs, spleen, pancreas, and gallbladder to the liver[BTO]. http://purl.obolibrary.org/obo/UBERON_0002025 stratum basale of epidermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells http://purl.obolibrary.org/obo/UBERON_0002031 epithelium of bronchus http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium An epithelium that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue that contains fibers that are divided by transverse bands into striations. http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anatomical structure that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0002051 epithelium of bronchiole http://purl.obolibrary.org/obo/UBERON_0003350 epithelium of mucosa An epithelium that is part of a bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002072 hypodermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. http://purl.obolibrary.org/obo/UBERON_0002090 postcranial axial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. http://purl.obolibrary.org/obo/UBERON_0002091 appendicular skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]. http://purl.obolibrary.org/obo/UBERON_0002097 skin of body http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure The organ covering the body that consists of the dermis and epidermis. http://purl.obolibrary.org/obo/UBERON_0002100 trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. http://purl.obolibrary.org/obo/UBERON_0002103 hindlimb http://purl.obolibrary.org/obo/UBERON_0004709 pelvic appendage A (free) limb that is connected to a pelvic girdle region. The extent of this structure includes autopod, stylopod and zeugopod regions when present, but excludes the pelvic girdle and its parts. http://purl.obolibrary.org/obo/UBERON_0002167 right lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA] http://purl.obolibrary.org/obo/UBERON_0002168 left lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the left upper lobe and left lower lobe.[FMA] http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube the conducting airway of the lungs found terminal to the bronchi; these structures contain neither cartilage nor mucous-secreting glands; the epithelium of the bronchioles becomes thinner with each branching http://purl.obolibrary.org/obo/UBERON_0002187 terminal bronchiole http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole the last conducting structure of non-respiratory bronchioles; after this point, the airways have alveoli in their walls http://purl.obolibrary.org/obo/UBERON_0002188 respiratory bronchiole http://purl.obolibrary.org/obo/UBERON_0002186 bronchiole A bronchiole that is the first segment of the respiratory zone. http://purl.obolibrary.org/obo/UBERON_0002193 hemolymphoid system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. http://purl.obolibrary.org/obo/UBERON_0002199 integument http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The dermis, epidermis and hypodermis. http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA] http://purl.obolibrary.org/obo/UBERON_0002294 biliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Organ system subdivision that consists of the organs and ducts that are involved in the production and transportation of bile. In most species this is the gallbladder and the bile ducts (biliary tree). http://purl.obolibrary.org/obo/UBERON_0002329 somite http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0002331 umbilical cord http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure The connecting cord from the developing embryo to the placenta. http://purl.obolibrary.org/obo/UBERON_0002342 neural crest http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. http://purl.obolibrary.org/obo/UBERON_0002346 neurectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Embryonic ectoderm that gives rise to nervous tissue. http://purl.obolibrary.org/obo/UBERON_0002355 pelvic region of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The lower segment of the trunk, inferioposterior to the abdomen proper, in the transition area between the trunk and the lower limbs. http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas http://purl.obolibrary.org/obo/UBERON_0002412 vertebra http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The ossified form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0002417 abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The abdominal segment of the torso. http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. http://purl.obolibrary.org/obo/UBERON_0002423 hepatobiliary system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The part of the digestive system that contains the liver and the biliary system http://purl.obolibrary.org/obo/UBERON_0002428 limb bone http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A bone that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002465 lymphoid system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The lymphatic system in vertebrates is a network of conduits that carry a clear fluid called lymph. It also includes the lymphoid tissue through which the lymph travels. Lymphoid tissue is found in many organs, particularly the lymph nodes, and in the lymphoid follicles associated with the digestive system such as the tonsils. The system also includes all the structures dedicated to the circulation and production of lymphocytes, which includes the spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system[WP]. http://purl.obolibrary.org/obo/UBERON_0002469 esophagus mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002472 stylopod http://purl.obolibrary.org/obo/UBERON_0002529 limb segment The proximal free limb segment. Includes as parts the stylopod skeleton. http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. http://purl.obolibrary.org/obo/UBERON_0002513 endochondral bone http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element Replacement bone that forms within cartilage. http://purl.obolibrary.org/obo/UBERON_0002515 periosteum http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer the thick fibrous membrane that closely invests the entire surface of a bone except the articular cartilage at synovial joints http://purl.obolibrary.org/obo/UBERON_0002529 limb segment http://purl.obolibrary.org/obo/UBERON_0010538 paired limb/fin segment A major subdivision of a mature or developing limb, including both skeletal elements (or the mesenchyme that gives rise to the skeletal elements) and associated tissues, such as muscle, connective tissue, integument. Examples: autopod region, zeugopod region, stylopod region, metapodial region, arm region. Excludes the limb girdles. http://purl.obolibrary.org/obo/UBERON_0002530 gland http://purl.obolibrary.org/obo/UBERON_0000062 organ an organ that functions as a secretory or excretory organ http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA] http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. http://purl.obolibrary.org/obo/UBERON_0003056 pre-chordal neural plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The portion of neural plate anterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003059 presomitic mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. http://purl.obolibrary.org/obo/UBERON_0003061 blood island http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. http://purl.obolibrary.org/obo/UBERON_0003064 intermediate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/UBERON_0003075 neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA] http://purl.obolibrary.org/obo/UBERON_0003077 paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO] http://purl.obolibrary.org/obo/UBERON_0003081 lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. http://purl.obolibrary.org/obo/UBERON_0003082 myotome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. http://purl.obolibrary.org/obo/UBERON_0003084 heart primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. http://purl.obolibrary.org/obo/UBERON_0003089 sclerotome http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. http://purl.obolibrary.org/obo/UBERON_0003100 female organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce female gametes. http://purl.obolibrary.org/obo/UBERON_0003101 male organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce male gametes. http://purl.obolibrary.org/obo/UBERON_0003102 surface structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. http://purl.obolibrary.org/obo/UBERON_0003103 compound organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue consisting of loosely organized undifferentiated mesodermal cells that give rise to such structures as connective tissues, blood, lymphatics, bone, and cartilage[XAO]. A mesh-like cell arrangement, less compact than an epithelium[ZFA]. The part of the embryonic mesoderm, consisting of loosely packed, unspecialized cells set in a gelatinous ground substance, from which connective tissue, bone, cartilage, and the circulatory and lymphatic systems develop[BTO]. http://purl.obolibrary.org/obo/UBERON_0003124 chorion http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure the outermost extraembryonic membrane http://purl.obolibrary.org/obo/UBERON_0003258 endoderm of foregut http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium An endoderm that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003262 amniotic mesoderm http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme A mesenchyme that is part of a amnion. http://purl.obolibrary.org/obo/UBERON_0003265 chorionic mesenchyme http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme A mesenchyme that is part of a chorion. http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003350 epithelium of mucosa http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A layer of epithelial cells on the surface of the mucosa. http://purl.obolibrary.org/obo/UBERON_0003353 epithelium of hindgut http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a hindgut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003374 chorionic ectoderm http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure A extraembryonic structure that develops_from a ectoderm and is part of a chorion. http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A gland that is part of a digestive tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003422 mesenchyme of umbilical cord http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue A gelatinous substance within the umbilical cord, largely made up of mucopolysaccharides (hyaluronic acid and chondroitin sulfate). It also contains some fibroblasts and macrophages. It is derived from Extra Embryonic Mesoderm[WP] http://purl.obolibrary.org/obo/UBERON_0003464 hindlimb bone http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A bone that is part of a hindlimb region. Examples: any pes phalanx, femur. Counter-examples: ischium, pubis (they are part of the pelvic girdle) http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta. http://purl.obolibrary.org/obo/UBERON_0003606 limb long bone http://purl.obolibrary.org/obo/UBERON_0002428 limb bone A long bone that is part of a limb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003608 hindlimb long bone http://purl.obolibrary.org/obo/UBERON_0003606 limb long bone A long bone that is part of a hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003714 neural tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. http://purl.obolibrary.org/obo/UBERON_0003820 prostate bud http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud A region of the fetal urogenital sinus epithelium destined to become the prostate[GO]. http://purl.obolibrary.org/obo/UBERON_0003826 upper leg bone http://purl.obolibrary.org/obo/UBERON_0005893 leg bone A bone that is part of a hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003860 hindlimb mesenchyme http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme Mesenchyme that is part of a developing hindlimb [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003894 liver primordium http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction A small endodermal thickening in the foregut adjacent to the transverse septum. Invaginates forming the hepatic diverticulum. http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that carries blood from the capillaries toward the heart http://purl.obolibrary.org/obo/UBERON_0003928 digestive system duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that lines the lumen of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. http://purl.obolibrary.org/obo/UBERON_0004016 dermatome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any tube, opening or passage that connects two distinct anatomical spaces. http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the endoderm. http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the mesoderm. http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the ectoderm. http://purl.obolibrary.org/obo/UBERON_0004122 genitourinary system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Anatomical system that has as its parts the organs concerned with the production and excretion of urine and those concerned with reproduction. http://purl.obolibrary.org/obo/UBERON_0004139 cardiogenic plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The first recognizable structure derived from the heart field http://purl.obolibrary.org/obo/UBERON_0004140 primary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. http://purl.obolibrary.org/obo/UBERON_0004141 heart tube http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure A cardiac chamber surrounds an enclosed cavity within the heart http://purl.obolibrary.org/obo/UBERON_0004161 septum transversum http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]. http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals http://purl.obolibrary.org/obo/UBERON_0004185 endodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portions of the gut that is derived from endoderm. http://purl.obolibrary.org/obo/UBERON_0004288 skeleton http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. http://purl.obolibrary.org/obo/UBERON_0004290 dermomyotome http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure The bilaminar epithelium formed from the myotome and dermatome. http://purl.obolibrary.org/obo/UBERON_0004291 heart rudiment http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/UBERON_0004340 allantois http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane A membranous sac that develops from the posterior part of the alimentary canal in the embryos of mammals, birds, and reptiles, and it is important in the formation of the umbilical cord and placenta in mammals[VHOG]. http://purl.obolibrary.org/obo/UBERON_0004345 trophectoderm http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition http://purl.obolibrary.org/obo/UBERON_0004347 limb bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud An outgrowth on the lateral trunk of the embryo that develops into a limb. The limb bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/UBERON_0004375 bone of free limb or fin http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of an appendage [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004381 skeleton of limb http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton The collection of all skeletal elements in an individual limb. http://purl.obolibrary.org/obo/UBERON_0004536 lymph vasculature http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure A network of blunt ended vessels lacking direct connection to the blood vascular system. These vessels collect and drain fluids and macromolecules from interstitial spaces throughout the animal. They derive from a subpopulation of endothelial cells and have walls that are much thinner than the blood carrying vessels. Lymphatic vessels are usually classified as either superficial or deep. http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vascular network consisting of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004572 arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all arteries. http://purl.obolibrary.org/obo/UBERON_0004582 venous system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions. http://purl.obolibrary.org/obo/UBERON_0004647 liver lobule http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure the polygonal structure of the liver that consists of hepatocytes radiating outward from a hepatic vein http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin http://purl.obolibrary.org/obo/UBERON_0000026 appendage An appendage that is part of an appendage girdle complex. http://purl.obolibrary.org/obo/UBERON_0004709 pelvic appendage http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin Paired appendage that consists of the posterior appendicular skeleton and associated soft and hard tissues, but excludes the pelvic girdle and its associated soft and hard tissues. http://purl.obolibrary.org/obo/UBERON_0004716 conceptus http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. http://purl.obolibrary.org/obo/UBERON_0004734 gastrula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the gastrula stage. http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO] http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. http://purl.obolibrary.org/obo/UBERON_0004770 articular system http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical system that consists of all the joints of the body. http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa the mucous membrane lining the respiratory tract http://purl.obolibrary.org/obo/UBERON_0004786 gastrointestinal system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a gastrointestinal system. http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium the pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004808 gastrointestinal system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium An epithelium that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004871 somatic layer of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Layer of lateral plate mesoderm that forms the future body wall - underlies the ectoderm[WP]. http://purl.obolibrary.org/obo/UBERON_0004872 splanchnic layer of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. http://purl.obolibrary.org/obo/UBERON_0004874 somatopleure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. http://purl.obolibrary.org/obo/UBERON_0004902 urogenital sinus epithelium http://purl.obolibrary.org/obo/UBERON_0009846 embryonic cloacal epithelium The fetal urogenital sinus (from which the prostate derives) is a simple cylinder of stratified basal epithelium, surrounded by mesenchyme and positioned between the embryonic bladder and pelvic urethra http://purl.obolibrary.org/obo/UBERON_0004905 articulation http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that connects two or more adjacent skeletal elements or hardened body parts. http://purl.obolibrary.org/obo/UBERON_0004908 upper digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum. http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A proximal-distal subdivision of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of a wall of an organ that forms a layer. http://purl.obolibrary.org/obo/UBERON_0005039 mucosa of bronchiole http://purl.obolibrary.org/obo/UBERON_0000410 bronchial mucosa A mucosa that is part of a bronchiole [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005061 neural groove http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds. http://purl.obolibrary.org/obo/UBERON_0005062 neural fold http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of the two elevated edges of the neural groove[GO,MP]. http://purl.obolibrary.org/obo/UBERON_0005068 neural rod http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]. http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold A bud is a protrusion that forms from an epithelial sheet by localized folding. http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any anatomical structure that is part of the reproductive system. http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet bent on a linear axis. http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. http://purl.obolibrary.org/obo/UBERON_0005254 upper leg mesenchyme http://purl.obolibrary.org/obo/UBERON_0003860 hindlimb mesenchyme Mesenchyme that is part of a developing hindlimb stylopod [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a developing trunk. http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue A portion of tissue that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. http://purl.obolibrary.org/obo/UBERON_0005399 male reproductive gland http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland A sex gland that is part of a male reproductive system. http://purl.obolibrary.org/obo/UBERON_0005418 hindlimb bud http://purl.obolibrary.org/obo/UBERON_0005420 pelvic appendage bud A limb bud that develops into a hindlimb. http://purl.obolibrary.org/obo/UBERON_0005420 pelvic appendage bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud A limb bud that develops into a hindlimb or pelvic fin. http://purl.obolibrary.org/obo/UBERON_0005428 vagal neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]. http://purl.obolibrary.org/obo/UBERON_0005498 primitive heart tube http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that arises from the heart rudiment and will become the heart tube. http://purl.obolibrary.org/obo/UBERON_0005564 gonad primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Portion of tissue that gives rise to the immature gonad. http://purl.obolibrary.org/obo/UBERON_0005597 lung primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum. http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo. http://purl.obolibrary.org/obo/UBERON_0005728 extraembryonic mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue . http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure A acellular anatomical structure that is the bounding layer of a anatomical structure. http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. http://purl.obolibrary.org/obo/UBERON_0005806 portal system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature In the circulatory system of animals, a portal venous system occurs when a capillary bed drains into another capillary bed through veins, without first going through the heart. Both capillary beds and the blood vessels that connect them are considered part of the portal venous system. They are relatively uncommon as the majority of capillary beds drain into veins which then drain into the heart, not into another capillary bed. Portal venous systems are considered venous because the blood vessels that join the two capillary beds are either veins or venules. Examples of such systems include the hepatic portal system and the hypophyseal portal system. Unqualified, 'portal venous system' often refers to the hepatic portal system. For this reason, 'portal vein' most commonly refers to the hepatic portal vein[WP]. http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation A delimited region of dense mesenchyme within looser mesenchyme. http://purl.obolibrary.org/obo/UBERON_0005863 cartilaginous condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. http://purl.obolibrary.org/obo/UBERON_0005893 leg bone http://purl.obolibrary.org/obo/UBERON_0003464 hindlimb bone A bone that is part of the region of the hindlimb that includes the zeugopod and stylopod. Examples: patella, femur, tibia. Counter-examples: any pes phalanx http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA] http://purl.obolibrary.org/obo/UBERON_0005944 axial skeleton plus cranial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. http://purl.obolibrary.org/obo/UBERON_0005971 amniotic fold http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure A sheet of somatopleure that grows upward over the embryo and eventually meets in the midline enclosing the embryo, eventually giving rise to the amnion and chorion[Kardong]. http://purl.obolibrary.org/obo/UBERON_0006058 multi-limb segment region http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis A collection of two or more connected limb segments. Examples: arm (comprising stylopod and zeugopod regions). http://purl.obolibrary.org/obo/UBERON_0006234 femur pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element A femur endochondral element that is composed primarily of a pre-cartilage condensation. http://purl.obolibrary.org/obo/UBERON_0006235 foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junctions that overlaps the foregut and midgut. http://purl.obolibrary.org/obo/UBERON_0006238 future brain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic precursor of the brain. http://purl.obolibrary.org/obo/UBERON_0006240 future forebrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a forebrain. http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. http://purl.obolibrary.org/obo/UBERON_0006595 presumptive endoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into endoderm. http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Portion of embryonic tissue determined by fate mapping to become a structure. http://purl.obolibrary.org/obo/UBERON_0006601 presumptive ectoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into ectoderm. http://purl.obolibrary.org/obo/UBERON_0006603 presumptive mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into mesoderm. http://purl.obolibrary.org/obo/UBERON_0006614 aponeurosis http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer A sheet of extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0006661 epicranial aponeurosis http://purl.obolibrary.org/obo/UBERON_0006614 aponeurosis The galea aponeurotica (epicranial aponeurosis, aponeurosis epicranialis) is a tough layer of dense fibrous tissue which covers the upper part of the cranium; behind, it is attached, in the interval between its union with the Occipitales, to the external occipital protuberance and highest nuchal lines of the occipital bone; in front, it forms a short and narrow prolongation between its union with the Frontales. On either side it gives origin to the Auriculares anterior and superior; in this situation it loses its aponeurotic character, and is continued over the temporal fascia to the zygomatic arch as a layer of laminated areolar tissue. It is closely connected to the integument by the firm, dense, fibro-fatty layer which forms the superficial fascia of the scalp: it is attached to the pericranium by loose cellular tissue, which allows the aponeurosis, carrying with it the integument to move through a considerable distance. http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is composed primarily of secretory cells. http://purl.obolibrary.org/obo/UBERON_0006815 areolar connective tissue http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand. http://purl.obolibrary.org/obo/UBERON_0006866 terminal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The distalmost portion of the digestive tract, derived from the hindgut, and terminating with the anus. http://purl.obolibrary.org/obo/UBERON_0006924 stomach glandular epithelium http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium A glandular epithelium that lines the stomach. The stomach's glandular epithelium is characterized by the presence of gastric glands. http://purl.obolibrary.org/obo/UBERON_0006925 digestive system gland http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any gland that is part of the digestive system. http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA] http://purl.obolibrary.org/obo/UBERON_0006931 stomach glandular region mucosa http://purl.obolibrary.org/obo/UBERON_0001199 mucosa of stomach stomach mucosa that is lined with glandular epithelium and part of a stomach glandular region. http://purl.obolibrary.org/obo/UBERON_0006965 vascular cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. http://purl.obolibrary.org/obo/UBERON_0007005 cardiogenic splanchnic mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. http://purl.obolibrary.org/obo/UBERON_0007010 cleaving embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the cleavage stage. http://purl.obolibrary.org/obo/UBERON_0007100 primary circulatory organ http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0007135 neural keel http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. http://purl.obolibrary.org/obo/UBERON_0007196 tracheobronchial tree http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells. http://purl.obolibrary.org/obo/UBERON_0007273 pelvic appendage skeleton http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton The collection of all skeletal elements in a pelvic appendage region. http://purl.obolibrary.org/obo/UBERON_0007282 presumptive segmental plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0007284 presumptive neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A presumptive structure that has the potential to develop into a neural plate. http://purl.obolibrary.org/obo/UBERON_0007285 presumptive paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The part of the blastula that has the potential to develop into a paraxial mesoderm. http://purl.obolibrary.org/obo/UBERON_0007376 outer epithelium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. http://purl.obolibrary.org/obo/UBERON_0007383 enveloping layer of ectoderm http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium Outermost layer of cells surrounding the embryo. http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac http://purl.obolibrary.org/obo/UBERON_0009856 sac An epithelial tube that is open at one end only. http://purl.obolibrary.org/obo/UBERON_0007500 epithelial tube open at both ends http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube An epithelial tube open at both ends that allows fluid flow. http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A closed epithelium with a lumen. http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme with little extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchymal cells that are migrating. http://purl.obolibrary.org/obo/UBERON_0007592 ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA] http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium bearing vibratile cilia on the free surface. http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that connects two structures http://purl.obolibrary.org/obo/UBERON_0007688 anlage http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. http://purl.obolibrary.org/obo/UBERON_0007806 connecting stalk http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure A bridge of mesoderm connecting the caudal end of the young embryo with the trophoblastic tissues; the precursor of the umbilical cord. http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. http://purl.obolibrary.org/obo/UBERON_0007823 appendage girdle region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0007832 pelvic girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton Skeletal subdivision consisting of a set of bones linking the axial series to the hindlimb zeugopodium and offering anchoring areas for hindlimb and caudal musculature. http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of cartilage tissue and may be permanent or transient. http://purl.obolibrary.org/obo/UBERON_0008001 irregular bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid. http://purl.obolibrary.org/obo/UBERON_0008780 inner cell mass derived epiblast http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers http://purl.obolibrary.org/obo/UBERON_0008784 lower limb segment http://purl.obolibrary.org/obo/UBERON_0002529 limb segment A limb segment that is part of a hindlimb. http://purl.obolibrary.org/obo/UBERON_0008835 hepatic diverticulum http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum An out-pocket of thickened ventral foregut epithelium adjacent to the developing heart. Constitutes the first morphological sign of the embryonic liver. The anterior portion of the hepatic diverticulum gives rise to the liver and intrahepatic biliary tree, while the posterior portion forms the gall bladder and extrahepatic bile ducts. http://purl.obolibrary.org/obo/UBERON_0008874 pulmonary acinus http://purl.obolibrary.org/obo/UBERON_0010368 pulmonary lobule The part of the airway consisting of a respiratory bronchiole and all of its branches http://purl.obolibrary.org/obo/UBERON_0009142 entire embryonic mesenchyme http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Sum total of mesenchyme in the embryo. http://purl.obolibrary.org/obo/UBERON_0009497 epithelium of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0009521 anal membrane endodermal component http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An endoderm that is part of a anal region. http://purl.obolibrary.org/obo/UBERON_0009550 endoderm of foregut-midgut junction http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a foregut-midgut junction. http://purl.obolibrary.org/obo/UBERON_0009749 limb mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The primordial embryonic connective tissue of the developing limbs, autopods and digits, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to limb connective tissue, bone and musculature in conjunction with myotome cells. http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form. http://purl.obolibrary.org/obo/UBERON_0009846 embryonic cloacal epithelium http://purl.obolibrary.org/obo/UBERON_0012481 cloacal epithelium An epithelium that is part of a embryonic cloaca. http://purl.obolibrary.org/obo/UBERON_0009847 prostate field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop. http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0009856 sac Branch or outpocketing of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A division of the stomach. The stomach can be divided based on mucosal histology (glandular epithelium and gastric glands) and the relative position and type of gastric gland. http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has more than one cell as a part. http://purl.obolibrary.org/obo/UBERON_0010039 food storage organ http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element An organ of the digestive tract that is capable of retaining and storing food http://purl.obolibrary.org/obo/UBERON_0010083 future dermis http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that has the potential to develop into a dermis. http://purl.obolibrary.org/obo/UBERON_0010129 femur cartilage element http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element A femur endochondral element that is composed primarily of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0010147 male accessory sex gland http://purl.obolibrary.org/obo/UBERON_0005399 male reproductive gland Any gland, other than the gonad, associated with the genital tract, such as the ampulla of the ductus deferens and the bulbourethral, prostate and vesicular glands of the male. http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has some part that develops from the neural crest. http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Mesenchyme that is part of a extraembryonic membrane. http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification. http://purl.obolibrary.org/obo/UBERON_0010368 pulmonary lobule http://purl.obolibrary.org/obo/UBERON_0009911 lobule The smallest anatomical unit of the lung, measuring 0.50 to 2.00 cm in diameter. Each lobule is composed of 4-8 terminal bronchioles and their distal alveolar ducts and sacs. The lobules are separated by fibrous interlobular septa. http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Epithelium composed of cells that develops from the ectoderm[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a somatopleure. http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels. http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile. http://purl.obolibrary.org/obo/UBERON_0010538 paired limb/fin segment http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis An appendage segment that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0010709 pelvic complex http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex Appendage girdle complex that when present, encompasses the pelvic appendicular skeleton and the pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that is a segment of the limb skeleton. http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The subdivision of the skeleton of either the pectoral or pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle). http://purl.obolibrary.org/obo/UBERON_0010742 bone of pelvic complex http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a pelvic complex. Examples: pubis, ischium, fot phalanx, any tarsal bone, any bone of the pelvic fin or girdle. http://purl.obolibrary.org/obo/UBERON_0010758 subdivision of organism along appendicular axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along an axis perpedicular to the main body anterior-posterior axis. In vertebrates, this is typically a fin or limb segment. In insects, this includes segments of appendages such as antennae, as well as segments of the insect leg. http://purl.obolibrary.org/obo/UBERON_0010881 limb cartilage element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A skeletal element that is part of a limb and composed of cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0010882 limb bone pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A skeletal element that is part of a limb and composed of pre-cartilage tissue. http://purl.obolibrary.org/obo/UBERON_0010885 hindlimb cartilage element http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A cartilaginous condensation that has the potential to develop into a hindlimb bone. http://purl.obolibrary.org/obo/UBERON_0010886 hindlimb pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A pre-cartilage condensation that has the potential to develop into a hindlimb bone. http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011094 vertebra cartilage element http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011095 vertebra pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0010913 vertebral element The pre-cartilaginous form of a vertebral element, a skeletal element that forms around the notochord and is part of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. http://purl.obolibrary.org/obo/UBERON_0011137 axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011138 postcranial axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A subdivision of an anatomical system. http://purl.obolibrary.org/obo/UBERON_0011249 appendicular skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in an individual limb or fin. http://purl.obolibrary.org/obo/UBERON_0011583 stylopodial skeleton http://purl.obolibrary.org/obo/UBERON_0010712 limb skeleton subdivision Proximal element of a free limb skeleton consisting of the femur and humerus in the forelimb stylopodium and hindlimb stylopodium respectively[VSAO, modified]. http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011695 embryonic cardiovascular system http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system A cardiovascular system that is part of a conceptus. http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus An acinus that is part of a exocrine gland. http://purl.obolibrary.org/obo/UBERON_0011953 stomach glandular region http://purl.obolibrary.org/obo/UBERON_0009870 zone of stomach A region of the stomach that is lined with glandular epithelium. http://purl.obolibrary.org/obo/UBERON_0012168 umbilical cord blood http://purl.obolibrary.org/obo/UBERON_0000178 blood blood that remains in the placenta and in the attached umbilical cord after childbirth[WP]. http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified] http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Epithelium that derives from the mesoderm. [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012429 hematopoietic tissue http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue Blood-forming tissue, consisting of reticular fibers and cells. http://purl.obolibrary.org/obo/UBERON_0012476 skeleton of pelvic complex http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in a pelvic complex - i.e. the combination of free limb or fin plus pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0012481 cloacal epithelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelium that is part of a cloaca. http://purl.obolibrary.org/obo/UBERON_0013515 subdivision of oviduct http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A section through the tube or network of tubes that connects the ovaries to the outside of the body. http://purl.obolibrary.org/obo/UBERON_0013686 anatomical conduit space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0013701 main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. http://purl.obolibrary.org/obo/UBERON_0013702 body proper http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The region of the organism associated with the visceral organs. http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A organ component layer that is part of a integumental system. http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element http://purl.obolibrary.org/obo/UBERON_0000062 organ Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. http://purl.obolibrary.org/obo/UBERON_0014477 thoracic skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. http://purl.obolibrary.org/obo/UBERON_0014716 interlobular duct http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct A duct that is located between lobules, within the thin connective tissue septa that separate lobules. All interlobular ducts are excretory. http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). http://purl.obolibrary.org/obo/UBERON_0014903 primordial vasculature http://purl.obolibrary.org/obo/UBERON_0001048 primordium A portion of tissue that will develop into vasculature. http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element A hindlimb bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015052 femur endochondral element http://purl.obolibrary.org/obo/UBERON_0015022 hindlimb endochondral element A femur bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015061 limb endochondral element http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element A limb bone or its cartilage or pre-cartilage precursor. http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any structure that is placed on one side of the left-right axis of a bilaterian. http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium A epithelium that is part of a foregut. http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the central nervous system http://purl.obolibrary.org/obo/UBERON_0016880 future nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the nervous system http://purl.obolibrary.org/obo/UBERON_0016887 entire extraembryonic component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure An multicellular anatomical structure that has subparts of multiple organs as a part. http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A cluster of cells, largely surrounded by a morphological boundary. http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity A collection of anatomical structures that are alike in terms of their morphology or developmental origin. http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure http://purl.obolibrary.org/obo/UBERON_0003102 surface structure Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0000001 cell line cell A cell line cell that is cultured in vitro and possesses two capabilities: (1) it can self-renew, which means that it can divide indefinitely while remaining in an undifferentiated state; and (2) it is pluripotent or multipotent, which means that it can differentiate to form a specialized cell type. http://purl.obolibrary.org/obo/NCIT_C120538 Cell Density http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum A measurement of the number of cells per unit volume or area. http://purl.obolibrary.org/obo/CLO_0000005 cell line repository role http://purl.obolibrary.org/obo/BFO_0000023 role a role that inheres in a cell line repository organization. http://purl.obolibrary.org/obo/CLO_0000008 cell line repository http://purl.obolibrary.org/obo/OBI_0000245 organization an organization that serves as a repository of cell lines. http://purl.obolibrary.org/obo/IAO_0020021 identity document http://purl.obolibrary.org/obo/IAO_0000310 document a document that denotes some identity and is concretized by the bearer of some credential role http://purl.obolibrary.org/obo/IAO_0020022 documented identity http://purl.obolibrary.org/obo/IAO_0000030 information content entity a documented identity is the aggregate of all data items about an entity. Notice that a documented identity is not itself a document since a document is intended to be understood as a whole and data items about an individual are usually scattered across different documents. http://purl.obolibrary.org/obo/IAO_0020023 authentication http://purl.obolibrary.org/obo/BFO_0000015 process Authentication is the act of checking or verifying an identity claim (that is either tacit or explicit). http://purl.obolibrary.org/obo/IAO_0020024 credential role http://purl.obolibrary.org/obo/BFO_0000023 role a role that inheres in a concretization of an identity document and is realized by an authentication process http://purl.obolibrary.org/obo/IAO_0021003 social act http://purl.obolibrary.org/obo/BFO_0000015 process A process that is carried out by a conscious being or an aggregate of conscious beings and is spontaneous, directed towards other conscious beings and aggregates thereof and needs to be perceived. http://purl.obolibrary.org/obo/OMRSE_00000083 OMB ethnic identity datum http://purl.obolibrary.org/obo/OMRSE_00000100 ethnic identity datum An ethnic identity datum that is the output of an ethnic identification process that uses OMB terminology for ethnicity or terminology that is mapped the OMB ethnicity terms. http://purl.obolibrary.org/obo/OMRSE_00000098 racial identity datum http://purl.obolibrary.org/obo/OMRSE_00000132 identity datum A racial identity is an information content entity that is the output of some racial identitification process and is intended to be a truthful statement about the genetic or cultural race of a person. Unlike data items they are not necessilary contributed or acquired by a reliable method. http://purl.obolibrary.org/obo/OMRSE_00000100 ethnic identity datum http://purl.obolibrary.org/obo/OMRSE_00000132 identity datum An ethnic identity datum is an information content entity that is the output of some ethnic identitification process and is intended to be a truthful statement about the cultural or national heritage of a person. Unlike data items they are not necessilary contributed or acquired by a reliable method. http://purl.obolibrary.org/obo/OMRSE_00000127 hispanic or latino identity datum http://purl.obolibrary.org/obo/OMRSE_00000083 OMB ethnic identity datum An OMB ethnic identity datum that indicates the person identified is of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin regardless of race. http://purl.obolibrary.org/obo/OMRSE_00000128 not hispanic or latino identity datum http://purl.obolibrary.org/obo/OMRSE_00000083 OMB ethnic identity datum An OMB ethnic identity datum that indicates the person identified is not of Cuban, Mexican, Puerto Rican, South or Central American, or other Spanish culture or origin regardless of race. http://purl.obolibrary.org/obo/OMRSE_00000132 identity datum http://purl.obolibrary.org/obo/IAO_0000030 information content entity An identity datum is an information content entity that is the output of some identitification process and is intended to be a truthful statement about a person's social identity. Unlike data items they are not necessilary contributed or acquired by a reliable method. http://purl.obolibrary.org/obo/OMRSE_00000133 gender identity datum http://purl.obolibrary.org/obo/OMRSE_00000132 identity datum A gender identity is an information content entity that is the output of some gender identitification process and is intended to be a truthful statement about a person's subjective sense of their gender. Unlike data items they are not necessilary contributed or acquired by a reliable method. http://purl.obolibrary.org/obo/OMRSE_00000180 American Indian or Alaska Native identity datum http://purl.obolibrary.org/obo/OMRSE_00000185 OMB racial identity datum A racial identity that is the output of a racial identification process that uses OMB terminology for race or terminology that is mapped the OMB race terms and that indicates that the subject of the identity has origins in any of the original peoples of North and South America (including Central America), and maintains tribal affiliation or community attachment. http://purl.obolibrary.org/obo/OMRSE_00000181 Asian identity datum http://purl.obolibrary.org/obo/OMRSE_00000185 OMB racial identity datum A racial identity that is the output of a racial identification process that uses OMB terminology for race or terminology that is mapped the OMB race terms and that indicates that the subject of the identity has origins in any of the original peoples of the Far East, Southeast Asia, or the Indian subcontinent. http://purl.obolibrary.org/obo/OMRSE_00000182 black or African American identity datum http://purl.obolibrary.org/obo/OMRSE_00000185 OMB racial identity datum A racial identity that is the output of a racial identification process that uses OMB terminology for race or terminology that is mapped the OMB race terms and that indicates that the subject of the identity has origins in any of the black racial groups of Africa. http://purl.obolibrary.org/obo/OMRSE_00000183 Native Hawaiian or other Pacific Islander identity datum http://purl.obolibrary.org/obo/OMRSE_00000185 OMB racial identity datum A racial identity that is the output of a racial identification process that uses OMB terminology for race or terminology that is mapped the OMB race terms and that indicates that the subject of the identity has origins in any of the original peoples of Hawaii, Guam, Samoa, or other Pacific Islands. http://purl.obolibrary.org/obo/OMRSE_00000184 white identity datum http://purl.obolibrary.org/obo/OMRSE_00000185 OMB racial identity datum A racial identity that is the output of a racial identification process that uses OMB terminology for race or terminology that is mapped the OMB race terms and that indicates that the subject of the identity has origins in any of the original peoples of Europe, the Middle East, or North Africa. http://purl.obolibrary.org/obo/OMRSE_00000185 OMB racial identity datum http://purl.obolibrary.org/obo/OMRSE_00000098 racial identity datum A racial identity that is the output of a racial identification process that uses OMB terminology for race or terminology that is mapped the OMB race terms. http://purl.obolibrary.org/obo/NCIT_C71329 HLA Typing http://purl.obolibrary.org/obo/OBI_0000443 analyte assay A process in which blood or tissue samples are analyzed to determine their human leukocyte antigen (HLA) profiles. http://purl.obolibrary.org/obo/CL_0002323 amniocyte http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell A cell of a fetus which is suspended in the amniotic fluid. Amniocytes are considered to arise from several tissues including fetal skin, the fetal urinary tract, umbilical cord, and the inner amniotic surface. http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/BFO_0000015 process A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0008150 biological_process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0040011 locomotion http://purl.obolibrary.org/obo/GO_0008150 biological_process Self-propelled movement of a cell or organism from one location to another. http://purl.obolibrary.org/obo/PR_000001002 CD19 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction. http://purl.obolibrary.org/obo/PR_000001003 CD34 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain http://purl.obolibrary.org/obo/PR_000025796 integrin alpha An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule. http://purl.obolibrary.org/obo/PR_000001012 integrin alpha-M http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. http://purl.obolibrary.org/obo/PR_000001014 receptor-type tyrosine-protein phosphatase C isoform CD45R http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C A receptor-type tyrosine-protein phosphatase C that is a translation product of a mature transcript of the PTPRC gene, that includes the region encoded by the variable exons 4(A), 5(B), and 6(C). Example: UniProtKB:P08575-1. http://purl.obolibrary.org/obo/PR_000001020 CD3 epsilon http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration. http://purl.obolibrary.org/obo/PR_000001024 neural cell adhesion molecule 1 http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001083 CD2 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain. http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267). http://purl.obolibrary.org/obo/PR_000001289 membrane-spanning 4-domains subfamily A member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001307 CD44 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD44 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001308 CD48 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD48 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001327 cadherin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. http://purl.obolibrary.org/obo/PR_000001345 endoglin http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human ENG gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV http://purl.obolibrary.org/obo/PR_000000001 protein A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III. http://purl.obolibrary.org/obo/PR_000001408 ADP-ribosyl cyclase 1 http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase An ADP-ribosyl cyclase that is a translation product of the human CD38 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001444 cadherin-5 http://purl.obolibrary.org/obo/PR_000001327 cadherin A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001483 low affinity immunoglobulin gamma Fc region receptor III http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001785 prominin http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001786 prominin-1 http://purl.obolibrary.org/obo/PR_000001785 prominin A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001800 5'-nucleotidase http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human NT5E gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001809 CD59-like glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the CD59 or closely related gene. This gene is present as a single copy in human and has undergone a lineage-specific duplication in mouse. CD59 antigen has a core architecture consisting of one UPAR/Ly-6 domain (Pfam:PF00021), a small domain of about 70 amino acids and containing 5 conserved disulfide bonds. It is both N- and O-glycosylated and is a GPI-anchored protein that releases soluble forms in some tissues. http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. http://purl.obolibrary.org/obo/PR_000001833 SLAM family member 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human SLAMF1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001839 T-cell surface glycoprotein CD5 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001843 Thy-1 membrane glycoprotein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001869 interleukin-7 receptor subunit alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the KLRB1 gene or its closely related paralogs (KLRB1A-F). There are lineage-specific expansions in mouse and rat. http://purl.obolibrary.org/obo/PR_000001889 CD14 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001892 CD33 molecule http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001896 natural killer cell receptor 2B4 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD244 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001932 signal transducer CD24 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human CD24 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, a Lectin C-type domain (Pfam:PF00059), 5 or 6 EGF-like domains (Pfam:PF00008, Pfam:PF09064, or Pfam:PF07645), a transmembrane region, and a small cytoplasmic region (36-51 amino acids). http://purl.obolibrary.org/obo/PR_000001945 transferrin receptor protein 1 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor http://purl.obolibrary.org/obo/PR_000000001 protein A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain. http://purl.obolibrary.org/obo/PR_000002001 receptor-type tyrosine-protein kinase FLT3 http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002037 complement component C1q receptor http://purl.obolibrary.org/obo/PR_000001938 thrombomodulin-like receptor A thrombomodulin-like receptor that is a translation product of the human CD93 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002065 mast/stem cell growth factor receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002112 vascular endothelial growth factor receptor 2 http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002976 ly-6-like protein http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is the translation product of any of the LY6 genes (LY6A-LY6I). http://purl.obolibrary.org/obo/PR_000002977 killer cell lectin-like receptor subfamily B member 1C http://purl.obolibrary.org/obo/PR_000001874 KLRB1-like protein A KLRB1-like protein that is a translation product of the mouse Klrb1c gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002978 lymphocyte antigen 6G http://purl.obolibrary.org/obo/PR_000002976 ly-6-like protein A ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002979 lymphocyte antigen 6A-2/6E-1 http://purl.obolibrary.org/obo/PR_000002976 ly-6-like protein A ly-6-like protein that is a translation product of the mouse Ly6a gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002981 lymphocyte antigen 76 http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is a translation product of the mouse Ly76 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000018263 amino acid chain http://purl.obolibrary.org/obo/BFO_0000040 material entity An organic amino compound that is a polymer of amino acid chain components (unmodified amino-acid residues and/or modified amino-acid residues linked by peptide bonds or derivatives of such bonds. http://purl.obolibrary.org/obo/PR_000025796 integrin alpha http://purl.obolibrary.org/obo/PR_000000001 protein A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif. http://purl.obolibrary.org/obo/CL_0011115 precursor cell http://purl.obolibrary.org/obo/CL_0000003 native cell A cell that, by division or terminal differentiation, can give rise to other cell types. http://purl.obolibrary.org/obo/UBERON_0036146 cardiopharyngeal field http://purl.obolibrary.org/obo/UBERON_0007688 anlage An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. http://purl.obolibrary.org/obo/OBI_0002444 measurand role http://purl.obolibrary.org/obo/BFO_0000023 role A role borne by a material entity and realized in an assay which achieves the objective to measure the magnitude/concentration/amount of the measurand in the entity bearing evaluant role. http://purl.obolibrary.org/obo/CL_0008011 skeletal muscle satellite stem cell http://purl.obolibrary.org/obo/CL_0000594 skeletal muscle satellite cell A skeletal muscle satellite cell that divides by stem cell division. A proportion of this population undergoes symmetric stem cell division, producing two skeletal muscle satellite stem cells. The rest undergo asymmetric stem cell division - retaining their identity while budding off a daughter cell that differentiates into an adult skeletal muscle myoblast. http://purl.obolibrary.org/obo/CL_0011012 neural crest cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. http://purl.obolibrary.org/obo/CL_2000033 limb basal cell of epidermis http://purl.obolibrary.org/obo/CL_0002187 basal cell of epidermis Any basal cell of epidermis that is part of a limb. http://purl.obolibrary.org/obo/CL_2000061 placental amniotic mesenchymal stromal cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell Any mesenchymal stem cell that is part of a placenta. http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Any migratory neural crest cell that is part of a cardiac neural crest. http://purl.obolibrary.org/obo/CL_2000079 mesenchymal stem cell of femoral bone marrow http://purl.obolibrary.org/obo/CL_0002540 mesenchymal stem cell of the bone marrow Any mesenchymal stem cell of the bone marrow that is part of a femur. http://purl.obolibrary.org/obo/CL_2000080 mesenchymal stem cell of abdominal adipose http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose Any mesenchymal stem cell of adipose that is part of a abdomen. http://purl.obolibrary.org/obo/CL_2000083 hair follicle dermal papilla cell of scalp http://purl.obolibrary.org/obo/CL_0000346 hair follicle dermal papilla cell Any hair follicle dermal papilla cell that is part of a scalp. http://purl.obolibrary.org/obo/CL_2000095 cord blood hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell Any hematopoietic stem cell that is part of a umbilical cord blood. http://purl.obolibrary.org/obo/OSCI_0000000 cell cutlture passage number http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum that records how many times a cell culture has been subcultured. http://purl.obolibrary.org/obo/OBI_0002197 tissue section thickness http://purl.obolibrary.org/obo/IAO_0000408 length measurement datum A length measurement datum that is the result of an assay measuring the thickness of a tissue section. http://purl.obolibrary.org/obo/OBI_0002205 histologic grade according to AJCC 7th edition http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system. http://purl.obolibrary.org/obo/OBI_0002215 histologic grade for ovarian tumor http://purl.obolibrary.org/obo/OBI_0001930 categorical value specification A categorical value specification that is a histologic grade assigned to a ovarian tumor. http://purl.obolibrary.org/obo/OBI_0002216 histologic grade for ovarian tumor according to a two-tier grading system http://purl.obolibrary.org/obo/OBI_0002215 histologic grade for ovarian tumor A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors. http://purl.obolibrary.org/obo/OBI_0002219 histologic grade for ovarian tumor according to the World Health Organization http://purl.obolibrary.org/obo/OBI_0002215 histologic grade for ovarian tumor A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO). http://purl.obolibrary.org/obo/OBI_0002394 number of pregnancies http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum of the total number of pregnancies a woman has had. http://purl.obolibrary.org/obo/OBI_0002395 number of live births http://purl.obolibrary.org/obo/IAO_0000109 measurement datum A measurement datum of the total number of live births a female has had. http://purl.obolibrary.org/obo/OBI_0002396 age when gave birth to first child http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum An age measurement datum performed on a female when her first biological child was born. http://purl.obolibrary.org/obo/OMRSE_00000138 female gender identity datum http://purl.obolibrary.org/obo/OMRSE_00000133 gender identity datum a gender identity datum resulting from a gender identification process in which ‘female’ is selected based on the participant's subjective sense of gender http://purl.obolibrary.org/obo/OMRSE_00000141 male gender identity datum http://purl.obolibrary.org/obo/OMRSE_00000133 gender identity datum a gender identity datum resulting from a gender identification process in which ‘male’ is selected based on the participant's subjective sense of gender http://www.ebi.ac.uk/efo/EFO_0000253 amyotrophic lateral sclerosis http://purl.obolibrary.org/obo/DOID_319 spinal cord disease Motor Neuron Disease, Amyotrophic Lateral Sclerosis http://www.ebi.ac.uk/efo/EFO_0002970 myopathy http://purl.obolibrary.org/obo/DOID_66 muscle tissue disease muscular disease http://purl.obolibrary.org/obo/BFO_0000148 zero-dimensional temporal region http://purl.obolibrary.org/obo/BFO_0000008 temporal region temporal instant. http://purl.obolibrary.org/obo/NCBITaxon_9606 Homo sapiens http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae "human" EXACT genbank_common_name [] http://purl.obolibrary.org/obo/PATO_0000047 sex http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://mged.sourceforge.net/ontologies/MGEDOntology.owl#sex http://purl.obolibrary.org/obo/PATO_0000384 male http://purl.obolibrary.org/obo/PATO_0000047 sex http://mged.sourceforge.net/ontologies/MGEDOntology.owl#male http://purl.obolibrary.org/obo/DOID_1289 degenerative disease http://purl.obolibrary.org/obo/DOID_344 disease of biological process "degenerative disease" EXACT [NCI2004_11_17:C27090] http://purl.obolibrary.org/obo/DOID_13137 hereditary motor neuropathy proximal type I http://purl.obolibrary.org/obo/DOID_12377 spinal muscular atrophy "infantile muscular atrophy" EXACT [CSP2005:2057-3620] http://purl.obolibrary.org/obo/DOID_319 spinal cord disease http://purl.obolibrary.org/obo/DOID_331 central nervous system disease "myelopathy" RELATED [] http://purl.obolibrary.org/obo/DOID_870 neuropathy http://purl.obolibrary.org/obo/DOID_863 nervous system disease "Neuropathy, NOS" EXACT [SNOMEDCT_2005_07_31:42658009] http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae "mice C57BL/6xCBA/CaJ hybrid" RELATED misspelling [] http://purl.obolibrary.org/obo/NCBITaxon_2 Bacteria http://purl.obolibrary.org/obo/OBI_0100026 organism eubacteria http://purl.obolibrary.org/obo/OGG_3000000059 ACTA2 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens MYMY5 http://purl.obolibrary.org/obo/OGG_3000000286 ANK1 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens SPH2 http://purl.obolibrary.org/obo/OGG_3000081706 PPP1R14C http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens NY-BR-81 http://purl.obolibrary.org/obo/OGG_3000090273 CEACAM21 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens R29124_1 http://purl.obolibrary.org/obo/OGG_3000092737 DNER http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens bet http://purl.obolibrary.org/obo/CLO_0037317 mouse embryonic stem cell line cell http://purl.obolibrary.org/obo/CLO_0037279 embryonic stem cell line cell mES cell line cell http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata bony vertebrates http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/OBI_0100026 organism eukaryotes http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires "Rodents and rabbits" EXACT genbank_common_name [] http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi tetrapods http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda amniotes http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota Theria http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota "mammals" RELATED blast_name [] http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria vertebrates http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria Craniata http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria placentals http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires "rodents" RELATED blast_name [] http://purl.obolibrary.org/obo/OGG_3000008490 RGS5 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens MSTP129 http://purl.obolibrary.org/obo/OGG_3000009568 GABBR2 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens HRIHFB2099 http://purl.obolibrary.org/obo/CLO_0025503 GM00232 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell GM00232 http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini "apes" EXACT common_name [] http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires "primates" RELATED blast_name [] http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/NCBITaxon_314295 Hominoidea "great apes" EXACT common_name [] http://purl.obolibrary.org/obo/OGG_3000055655 NLRP2 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens CLR19.9 http://purl.obolibrary.org/obo/OGG_3000055824 PAG1 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens PAG http://purl.obolibrary.org/obo/DOID_4874 neurodegenerative disease http://purl.obolibrary.org/obo/DOID_863 nervous system disease "Neurodegenerative disease" EXACT [NCI2004_11_17:C4802] http://www.ebi.ac.uk/efo/EFO_0000801 muscular system http://www.ebi.ac.uk/efo/EFO_0000635 organism part muscule system http://www.ebi.ac.uk/efo/EFO_0000908 central nervous system http://www.ebi.ac.uk/efo/EFO_0000802 nervous system Neuraxis http://purl.obolibrary.org/obo/OGG_3000006876 TAGLN http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens TAGLN1 http://purl.obolibrary.org/obo/CLO_0037280 human embryonic stem cell line cell http://purl.obolibrary.org/obo/CLO_0037279 embryonic stem cell line cell hES cell line cell http://purl.obolibrary.org/obo/DOID_440 neuromuscular disease http://purl.obolibrary.org/obo/DOID_870 neuropathy http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037301 primary cultured fibroblast cell http://purl.obolibrary.org/obo/CLO_0037304 hematopoetic stem cell line cell http://purl.obolibrary.org/obo/CLO_0037303 adult stem cell line cell http://purl.obolibrary.org/obo/CLO_0037305 mesenchymal stem cell line cell http://purl.obolibrary.org/obo/CLO_0037303 adult stem cell line cell http://purl.obolibrary.org/obo/CLO_0037306 umbilical cord mesenchymal stem cell line cell http://purl.obolibrary.org/obo/CLO_0037305 mesenchymal stem cell line cell http://purl.obolibrary.org/obo/CLO_0037308 human induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037307 induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037308 human induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/PATO_0001396 cellular quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/PATO_0001400 unipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency http://purl.obolibrary.org/obo/PATO_0001403 pluripotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency http://purl.obolibrary.org/obo/DOID_4873 anterior horn cell disease http://purl.obolibrary.org/obo/DOID_481 hereditary degenerative disease of central nervous system http://purl.obolibrary.org/obo/DOID_231 motor neuron disease http://purl.obolibrary.org/obo/DOID_4874 neurodegenerative disease http://purl.obolibrary.org/obo/BFO_0000008 temporal region http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000011 spatiotemporal region http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000028 three-dimensional spatial region http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000034 function http://purl.obolibrary.org/obo/BFO_0000016 disposition http://www.ebi.ac.uk/efo/EFO_0000408 disease http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/OSCI_0000001 gene marker role http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/OSCI_0000021 feeder cell role http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/GO_0005575 cellular_component http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/CARO_0000006 material anatomical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000006 spatial region http://purl.obolibrary.org/obo/BFO_0000141 immaterial entity http://purl.obolibrary.org/obo/OSCI_0000036 concentration measurment datum http://purl.obolibrary.org/obo/IAO_0000032 scalar measurement datum http://purl.obolibrary.org/obo/IAO_0000582 time stamped measurement datum http://purl.obolibrary.org/obo/IAO_0000109 measurement datum http://purl.obolibrary.org/obo/OMRSE_00000134 identification process http://purl.obolibrary.org/obo/IAO_0021003 social act http://purl.obolibrary.org/obo/OSCI_0000035 cell culture medium additive http://purl.obolibrary.org/obo/OBI_0000047 processed material http://purl.obolibrary.org/obo/OSCI_0000031 TeSR http://purl.obolibrary.org/obo/OBI_0000079 culture medium http://purl.obolibrary.org/obo/OSCI_0000032 DMEM http://purl.obolibrary.org/obo/OBI_0000079 culture medium http://purl.obolibrary.org/obo/OSCI_0000033 F12 http://purl.obolibrary.org/obo/OBI_0000079 culture medium http://purl.obolibrary.org/obo/OSCI_0000011 stem cell producer http://purl.obolibrary.org/obo/OBI_0000245 organization http://purl.obolibrary.org/obo/OSCI_0000012 stem cell provider http://purl.obolibrary.org/obo/OBI_0000245 organization http://purl.obolibrary.org/obo/OSCI_0000017 cell line testing laboratory http://purl.obolibrary.org/obo/OBI_0000245 organization http://purl.obolibrary.org/obo/OSCI_0000023 feeder cell preparation protocol http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/OSCI_0000024 source cell storage/master cell banking protocol http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/OSCI_0000025 source cell procurement protocol http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/OSCI_0000026 material transferring protocol http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/OSCI_0000027 cell passage protocol http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/OSCI_0000028 establishment protocol (molecular induction protocol) http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/OSCI_0000029 cell culture protocol http://purl.obolibrary.org/obo/OBI_0000272 protocol http://purl.obolibrary.org/obo/OSCI_0000034 cell culture additive role http://purl.obolibrary.org/obo/OBI_0000319 material to be added role http://purl.obolibrary.org/obo/OSCI_0000016 age of donor at time of donation http://purl.obolibrary.org/obo/OBI_0001167 age measurement datum http://purl.obolibrary.org/obo/NCBITaxon_10239 Viruses http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/NCBITaxon_2157 Archaea http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/OSCI_0000030 donor http://purl.obolibrary.org/obo/OBI_0100026 organism http://purl.obolibrary.org/obo/PATO_0001397 cellular potency http://purl.obolibrary.org/obo/PATO_0001396 cellular quality http://purl.obolibrary.org/obo/CLO_0037250 mouse neural progenitor cell line cell http://purl.obolibrary.org/obo/CLO_0037245 mouse stem cell line cell http://purl.obolibrary.org/obo/CLO_0037251 C17.2 cell http://purl.obolibrary.org/obo/CLO_0037250 mouse neural progenitor cell line cell http://purl.obolibrary.org/obo/OSCI_0000022 feeder cell http://purl.obolibrary.org/obo/GO_0005623 cell http://purl.obolibrary.org/obo/CLO_0037321 primary cultured connective tissue cell http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CLO_0037453 W14-C146 cell http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CLO_0037454 F13-C004 cell http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CLO_0037455 W15-C166 cell http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CLO_0037456 SAB-701-022 cell http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CLO_0037457 W14-C138 cell http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CLO_0037458 W14-C152 cell http://purl.obolibrary.org/obo/CL_0000001 primary cultured cell http://purl.obolibrary.org/obo/CL_0000197 receptor cell http://purl.obolibrary.org/obo/CL_0000003 native cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell http://purl.obolibrary.org/obo/CL_0000003 native cell http://purl.obolibrary.org/obo/CL_0000016 male germ line stem cell http://purl.obolibrary.org/obo/CL_0000015 male germ cell http://purl.obolibrary.org/obo/CL_0000022 female germ line stem cell http://purl.obolibrary.org/obo/CL_0000021 female germ cell http://purl.obolibrary.org/obo/CL_0000085 germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000014 germ line stem cell http://purl.obolibrary.org/obo/CL_0000086 germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000014 germ line stem cell http://purl.obolibrary.org/obo/CL_0000087 male germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000086 germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000089 male germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000085 germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000088 female germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000086 germ line stem cell (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000090 female germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000085 germ line stem cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000338 neuroblast (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_0000031 neuroblast http://purl.obolibrary.org/obo/CL_1000042 forebrain neuroblast http://purl.obolibrary.org/obo/CL_0000031 neuroblast http://purl.obolibrary.org/obo/CL_0000014 germ line stem cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/CL_0000356 hair matrix stem cell http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/CL_0000357 stratified epithelial stem cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell http://purl.obolibrary.org/obo/CL_0000441 follicle stem cell http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell http://purl.obolibrary.org/obo/CL_0000468 neuroglioblast http://purl.obolibrary.org/obo/CL_0000055 non-terminally differentiated cell http://purl.obolibrary.org/obo/CL_0000354 blastemal cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell http://purl.obolibrary.org/obo/CL_0000076 squamous epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell http://purl.obolibrary.org/obo/CL_0000079 stratified epithelial cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell http://purl.obolibrary.org/obo/CL_0000082 epithelial cell of lung http://purl.obolibrary.org/obo/CL_0000066 epithelial cell http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0000377 tracheoblast http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0000240 stratified squamous epithelial cell http://purl.obolibrary.org/obo/CL_0000079 stratified epithelial cell http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell http://purl.obolibrary.org/obo/CL_0000197 receptor cell http://purl.obolibrary.org/obo/CL_0000324 metanephric mesenchyme stem cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0000383 nephrogenic mesenchyme stem cell http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0000114 surface ectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell http://purl.obolibrary.org/obo/CL_0000237 keratinizing barrier epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0000548 animal cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell http://purl.obolibrary.org/obo/CL_0000311 keratin accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000008 migratory cranial neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell http://purl.obolibrary.org/obo/CL_0000011 migratory trunk neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell http://purl.obolibrary.org/obo/CL_0000405 neuroepidermoblast http://purl.obolibrary.org/obo/CL_0000338 neuroblast (sensu Nematoda and Protostomia) http://purl.obolibrary.org/obo/CL_1000083 stratified keratinized epithelial stem cell http://purl.obolibrary.org/obo/CL_0000357 stratified epithelial stem cell http://purl.obolibrary.org/obo/CL_1000085 stratified non keratinized epithelial stem cell http://purl.obolibrary.org/obo/CL_0000357 stratified epithelial stem cell http://purl.obolibrary.org/obo/CL_0000469 ganglion mother cell http://purl.obolibrary.org/obo/CL_0000468 neuroglioblast http://purl.obolibrary.org/obo/CL_0000662 neuroglioblast (sensu Nematoda) http://purl.obolibrary.org/obo/CL_0000468 neuroglioblast http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell http://purl.obolibrary.org/obo/CL_0002371 somatic cell http://purl.obolibrary.org/obo/CL_0000015 male germ cell http://purl.obolibrary.org/obo/CL_0000586 germ cell http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract http://purl.obolibrary.org/obo/CL_0002368 respiratory epithelial cell http://purl.obolibrary.org/obo/DOID_44 tissue disease http://purl.obolibrary.org/obo/DOID_17 musculoskeletal system disease http://purl.obolibrary.org/obo/DOID_12377 spinal muscular atrophy http://purl.obolibrary.org/obo/DOID_319 spinal cord disease http://purl.obolibrary.org/obo/DOID_481 hereditary degenerative disease of central nervous system http://purl.obolibrary.org/obo/DOID_440 neuromuscular disease http://purl.obolibrary.org/obo/DOID_863 nervous system disease http://purl.obolibrary.org/obo/DOID_7 disease of anatomical entity http://purl.obolibrary.org/obo/DOID_331 central nervous system disease http://purl.obolibrary.org/obo/DOID_863 nervous system disease http://purl.obolibrary.org/obo/OGG_3000050509 COL5A3 http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens http://purl.obolibrary.org/obo/OGG_3000007425 VGF http://purl.obolibrary.org/obo/OGG_2060009606 protein-coding gene of Homo sapiens http://purl.obolibrary.org/obo/OGG_3000387845 EEF1A1P16 http://purl.obolibrary.org/obo/OGG_2070009606 pseudo gene of Homo sapiens http://purl.obolibrary.org/obo/CLO_0037319 human embryonic stem cell line cell derived by somatic cell nuclear transfer http://purl.obolibrary.org/obo/CLO_0037280 human embryonic stem cell line cell http://purl.obolibrary.org/obo/CLO_0037500 CS14iCTR-n6 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037501 CS83iCTR-33n1 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037502 CS25iCTR-18n2 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037503 CS28iALS-n2A cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037504 CS29iALS-n1N cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037505 CS30iALS-n1N cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037506 CS52iALS-n6A cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037507 CS32iSMA-n3 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037508 CS83iSMA-n5 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037509 CS77iSMA-n5 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037510 MSN01-3 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037511 MSN03-7 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037512 MSN05-1 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037513 MSN06-7 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037514 MSN02-4 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037515 MSN08-13 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037516 MSN09-4 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037517 MSN10-1 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037521 CS00iCTR-n2 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037522 CS29iALS-C9n1 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037523 CS30iALS-C9n1 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037528 CS28iALS-C9n2 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037529 CS52iALS-C9n6 cell http://purl.obolibrary.org/obo/CLO_0037320 human fibroblast-induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037301 primary cultured fibroblast cell http://purl.obolibrary.org/obo/CLO_0037321 primary cultured connective tissue cell http://purl.obolibrary.org/obo/GO_0005623 cell http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/GO_0044464 cell part http://purl.obolibrary.org/obo/CARO_0000014 cell part http://purl.obolibrary.org/obo/GO_0032991 macromolecular complex http://purl.obolibrary.org/obo/GO_0005575 cellular_component http://purl.obolibrary.org/obo/GO_0044425 membrane part http://purl.obolibrary.org/obo/GO_0005575 cellular_component http://purl.obolibrary.org/obo/GO_0071702 organic substance transport http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0048870 cell motility http://purl.obolibrary.org/obo/GO_0040011 locomotion http://purl.obolibrary.org/obo/GO_0007292 female gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation http://purl.obolibrary.org/obo/GO_0048232 male gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation http://purl.obolibrary.org/obo/GO_0048477 oogenesis http://purl.obolibrary.org/obo/GO_0007292 female gamete generation http://purl.obolibrary.org/obo/GO_0015833 peptide transport http://purl.obolibrary.org/obo/GO_0071702 organic substance transport http://purl.obolibrary.org/obo/GO_0044459 plasma membrane part http://purl.obolibrary.org/obo/GO_0044425 membrane part http://purl.obolibrary.org/obo/GO_0007283 spermatogenesis http://purl.obolibrary.org/obo/GO_0048232 male gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0051234 establishment of localization http://purl.obolibrary.org/obo/GO_0042886 amide transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0050912 detection of chemical stimulus involved in sensory perception of taste http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0051272 positive regulation of cellular component movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0065007 biological regulation http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_33553 Sciurognathi http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/NCBITaxon_33553 Sciurognathi http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://purl.obolibrary.org/obo/UBERON_0035050 excretory duct http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0009856 sac http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0018254 skeletal musculature http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0009911 lobule http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0000153 anterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0000154 posterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0003254 amniotic ectoderm http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0012361 internal anal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0011272 embryonic skin basal layer http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium http://purl.obolibrary.org/obo/UBERON_0008947 respiratory primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://www.ebi.ac.uk/efo/EFO_0000635 organism part http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity http://purl.obolibrary.org/obo/UBERON_0008202 bone of hip region http://purl.obolibrary.org/obo/UBERON_0001474 bone element http://purl.obolibrary.org/obo/UBERON_0003080 anterior neural tube http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0009881 anterior lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0004912 biliary bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0008836 liver bud http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0015410 heart plus pericardium http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0009618 trunk paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0005795 embryonic uterus http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0006596 presumptive blood http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0007026 presumptive gut http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/CLO_0037303 adult stem cell line cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037307 induced pluripotent stem cell line cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037245 mouse stem cell line cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037318 somatic cell nuclear transfer-derived stem cell line cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037518 FIBRNPC cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037519 CS14isALS-Tn16 cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037520 CS04iALS-SOD1H44Rn3 cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037524 CS166isALS-Tn2 cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037525 CS22iALS-SOD1I113Tn2 cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037526 CS138isALS-Tn1 cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037527 CS152isALS-Tn2 cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037530 CS11iALS-SOD1I113Tn10 cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/CLO_0037279 embryonic stem cell line cell http://purl.obolibrary.org/obo/CLO_0037224 stem cell line cell http://purl.obolibrary.org/obo/DOID_344 disease of biological process http://www.ebi.ac.uk/efo/EFO_0000408 disease http://www.ebi.ac.uk/efo/EFO_0000802 nervous system http://www.ebi.ac.uk/efo/EFO_0000635 organism part http://purl.obolibrary.org/obo/OMRSE_00000099 racial identification process http://purl.obolibrary.org/obo/OMRSE_00000134 identification process http://purl.obolibrary.org/obo/OMRSE_00000101 ethnic identification process http://purl.obolibrary.org/obo/OMRSE_00000134 identification process http://purl.obolibrary.org/obo/OMRSE_00000135 gender identification process http://purl.obolibrary.org/obo/OMRSE_00000134 identification process http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002376 immune system process http://purl.obolibrary.org/obo/GO_0002775 antimicrobial peptide production http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration http://purl.obolibrary.org/obo/GO_0002687 positive regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0002690 positive regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis http://purl.obolibrary.org/obo/GO_1902624 positive regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_1902622 regulation of neutrophil migration http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002776 antimicrobial peptide secretion http://purl.obolibrary.org/obo/GO_0002790 peptide secretion http://purl.obolibrary.org/obo/GO_0007281 germ cell development http://purl.obolibrary.org/obo/GO_0048468 cell development http://purl.obolibrary.org/obo/GO_0050877 nervous system process http://purl.obolibrary.org/obo/GO_0003008 system process http://purl.obolibrary.org/obo/GO_0050896 response to stimulus http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0065007 biological regulation http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0002376 immune system process http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0023052 signaling http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0051179 localization http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/OSCI_0000004 stem cell marker process http://purl.obolibrary.org/obo/GO_0008150 biological_process http://purl.obolibrary.org/obo/GO_0006928 movement of cell or subcellular component http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0032940 secretion by cell http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0051301 cell division http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0002790 peptide secretion http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0001649 osteoblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0060591 chondroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0003008 system process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process http://purl.obolibrary.org/obo/GO_0035637 multicellular organismal signaling http://purl.obolibrary.org/obo/GO_0023052 signaling http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0043234 protein complex http://purl.obolibrary.org/obo/GO_0032991 macromolecular complex http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex http://purl.obolibrary.org/obo/GO_0044425 membrane part http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process http://purl.obolibrary.org/obo/GO_0032101 regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048468 cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0016477 cell migration http://purl.obolibrary.org/obo/GO_0048870 cell motility http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0032879 regulation of localization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0051270 regulation of cellular component movement http://purl.obolibrary.org/obo/GO_0032879 regulation of localization http://purl.obolibrary.org/obo/GO_0019226 transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0035637 multicellular organismal signaling http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0017145 stem cell division http://purl.obolibrary.org/obo/GO_0051301 cell division http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex http://purl.obolibrary.org/obo/GO_0042613 MHC class II protein complex http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex http://purl.obolibrary.org/obo/GO_0051234 establishment of localization http://purl.obolibrary.org/obo/GO_0051179 localization http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation http://purl.obolibrary.org/obo/GO_0090023 positive regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0090022 regulation of neutrophil chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0048103 somatic stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/CARO_0000014 cell part http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/CARO_0000003 anatomical structure http://purl.obolibrary.org/obo/CARO_0000006 material anatomical entity http://purl.obolibrary.org/obo/CLO_0037413 GM03814 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037414 GM02183 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037415 ND30625 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037416 F09128 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037417 F09229 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037418 F10-330 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037419 F09152 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037421 83 Fibroblast cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037422 GM09677 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037423 MSF01 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037424 MSF02 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037425 MSF03 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037427 MSF05 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037428 MSF06 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037430 MSF08 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037431 MSF09 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037432 MSF10 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/CLO_0037443 GM05400 cell http://purl.obolibrary.org/obo/CLO_0037302 primary cultured human fibroblast cell http://purl.obolibrary.org/obo/NCBITaxon_9526 Catarrhini http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_314293 Simiiformes http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_207598 Homininae http://purl.obolibrary.org/obo/NCBITaxon_9604 Hominidae http://purl.obolibrary.org/obo/OSCI_0000005 neural stem cell marker process http://purl.obolibrary.org/obo/OSCI_0000004 stem cell marker process http://purl.obolibrary.org/obo/OSCI_0000006 iPSC marker process http://purl.obolibrary.org/obo/OSCI_0000004 stem cell marker process http://purl.obolibrary.org/obo/DOID_66 muscle tissue disease http://purl.obolibrary.org/obo/DOID_44 tissue disease http://purl.obolibrary.org/obo/CLO_0037313 H9 ES cell http://purl.obolibrary.org/obo/CLO_0037280 human embryonic stem cell line cell http://purl.obolibrary.org/obo/CLO_0037316 HUES3 ES cell http://purl.obolibrary.org/obo/CLO_0037280 human embryonic stem cell line cell http://purl.obolibrary.org/obo/CLO_0037281 Line H1 cell http://purl.obolibrary.org/obo/CLO_0037280 human embryonic stem cell line cell http://purl.obolibrary.org/obo/BFO_0000001 entity http://www.geneontology.org/formats/oboInOwl#ObsoleteClass obsolete class http://purl.obolibrary.org/obo/RO_0000079 function of http://purl.obolibrary.org/obo/RO_0000052 inheres in is function of a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000085 has function http://purl.obolibrary.org/obo/RO_0000053 is bearer of has_function a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/RO_0002131 overlaps has_part a core relation that holds between a whole and its part http://purl.obolibrary.org/obo/RO_0000087 has role http://purl.obolibrary.org/obo/RO_0000053 is bearer of has_role a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000081 role of http://purl.obolibrary.org/obo/RO_0000052 inheres in role_of a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/BFO_0000050 part of http://purl.obolibrary.org/obo/RO_0002131 overlaps part_of a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/BFO_0000138 proper part of occurrent http://purl.obolibrary.org/obo/BFO_0000132 part of occurrent b proper_occurrent_part_of c =Def. b occurrent_part_of c & b and c are not identical. (axiom label in BFO2 Reference: [005-001]) http://purl.obolibrary.org/obo/BFO_0000139 temporal part of http://purl.obolibrary.org/obo/BFO_0000132 part of occurrent b temporal_part_of c =Def.b occurrent_part_of c & & for some temporal region t, b occupies_temporal_region t & for all occurrents d, t (if d occupies_temporal_region t & t? occurrent_part_of t then (d occurrent_part_of a iff d occurrent_part_of b)). (axiom label in BFO2 Reference: [078-003]) http://purl.obolibrary.org/obo/BFO_0000158 bearer of at all times http://purl.obolibrary.org/obo/BFO_0000168 has specific dependent at all times b bearer_of c at t =Def. c s-depends_on b at t & b is an independent continuant that is not a spatial region. (axiom label in BFO2 Reference: [053-004]) http://purl.obolibrary.org/obo/BFO_0000186 part of continuant at all times that whole exists http://purl.obolibrary.org/obo/BFO_0000176 part of continuant at some time [copied from inverse property 'has continuant part at all times'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by http://purl.obolibrary.org/obo/RO_0002324 developmentally related to Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving Inverse of developmentally preceded by http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving http://purl.obolibrary.org/obo/RO_0002324 developmentally related to x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). http://purl.obolibrary.org/obo/RO_0002388 has potential to directly develop into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y http://purl.obolibrary.org/obo/IAO_0000219 denotes http://purl.obolibrary.org/obo/IAO_0000136 is about denotes is a primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically http://purl.obolibrary.org/obo/IAO_0000221 is quality measurement of http://purl.obolibrary.org/obo/IAO_0000136 is about m is a quality measurement of q at t when q is a quality there is a measurement process p that has specified output m, a measurement datum, that is about q http://purl.obolibrary.org/obo/IAO_0000413 is duration of http://purl.obolibrary.org/obo/IAO_0000136 is about relates a process to a time-measurement-datum that represents the duration of the process http://purl.obolibrary.org/obo/IAO_0000581 has time stamp http://purl.obolibrary.org/obo/BFO_0000051 has part relates a time stamped measurement datum to the time measurement datum that denotes the time when the measurement was taken http://purl.obolibrary.org/obo/IAO_0000583 has measurement datum http://purl.obolibrary.org/obo/BFO_0000051 has part relates a time stamped measurement datum to the measurement datum that was measured http://purl.obolibrary.org/obo/OBI_0000293 has_specified_input http://purl.obolibrary.org/obo/RO_0000057 has_participant A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. http://purl.obolibrary.org/obo/OBI_0000295 is_specified_input_of http://purl.obolibrary.org/obo/RO_0000056 participates in A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. http://purl.obolibrary.org/obo/OBI_0000299 has_specified_output http://purl.obolibrary.org/obo/RO_0000057 has_participant A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. http://purl.obolibrary.org/obo/OBI_0000312 is_specified_output_of http://purl.obolibrary.org/obo/RO_0000056 participates in A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. http://purl.obolibrary.org/obo/OBI_0000643 has grain http://purl.obolibrary.org/obo/BFO_0000051 has part the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car. http://purl.obolibrary.org/obo/OBI_0000999 has category label http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between a categorical measurement data item and the categorical label that indicates the value of that data item on the categorical scale. http://purl.obolibrary.org/obo/OBI_0001927 specifies value of http://purl.obolibrary.org/obo/IAO_0000136 is about A relation between a value specification and an entity which the specification is about. http://purl.obolibrary.org/obo/OBI_0001937 has specified numeric value http://purl.obolibrary.org/obo/OBI_0002135 has specified value A relation between a value specification and a number that quantifies it. http://purl.obolibrary.org/obo/OBI_0001938 has value specification http://purl.obolibrary.org/obo/BFO_0000051 has part A relation between an information content entity and a value specification that specifies its value. http://purl.obolibrary.org/obo/RO_0002220 adjacent to http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from x adjacent to y if and only if x and y share a boundary http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 part of inverse of starts with http://purl.obolibrary.org/obo/RO_0002202 develops from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y http://purl.obolibrary.org/obo/OGG_0000000014 is genome of organism http://purl.obolibrary.org/obo/BFO_0000176 part of continuant at some time a 'part of continuant at some time' relation that incides a genome belongs to a organism. http://purl.obolibrary.org/obo/OGG_0000000016 is gene of organism http://purl.obolibrary.org/obo/BFO_0000176 part of continuant at some time a relation between a gene and the organism where this gene belongs to the organism in nature. It does not include a foreign gene that is transferred to an organism by a genetic engineering method. http://purl.obolibrary.org/obo/BFO_0000187 has continuant part at all times that part exists http://purl.obolibrary.org/obo/BFO_0000178 has continuant part at some time forall(t) exists_at(y,t) -> exists_at(x,t) and 'has continuant part'(x,y,t) http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/BFO_0000052 inheres in at all times http://purl.obolibrary.org/obo/BFO_0000070 specifically depends on at all times b inheres_in c at t =Def. b is a dependent continuant & c is an independent continuant that is not a spatial region & b s-depends_on c at t. (axiom label in BFO2 Reference: [051-002]) http://purl.obolibrary.org/obo/CLO_0037207 derived from organism http://purl.obolibrary.org/obo/RO_0001000 derives from a 'cell line cell derives from' object property between an entity (e.g., cell line cell in CLO) and an organism where the cell line cell is derived from some cell from the organism. In CLO, this is a short cut relation that represents: 'derived from' some (cell and ('part of' some organism)) http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A is spatially_disjoint_from B if and only if they have no parts in common http://purl.obolibrary.org/obo/cl#has_low_plasma_membrane_amount has_low_plasma_membrane_amount http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. For the formal definition, see Masci et al (PMID:19243617). http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part http://purl.obolibrary.org/obo/BFO_0000051 has part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. http://purl.obolibrary.org/obo/RO_0002215 capable of http://purl.obolibrary.org/obo/RO_0002216 capable of part of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has the potential to develop into y iff x develops into y or if x is capable of developing into y http://purl.obolibrary.org/obo/BFO_0000162 has disposition at all times http://purl.obolibrary.org/obo/BFO_0000158 bearer of at all times a has_disposition b at t =Def. b disposition_of a at t. (axiom label in BFO2 Reference: [069-001]) http://purl.obolibrary.org/obo/BFO_0000118 has proper occurrent part http://purl.obolibrary.org/obo/BFO_0000117 has occurrent part b has_proper_occurrent_part c = Def. c proper_occurrent_part_of b. [XXX-001 http://purl.obolibrary.org/obo/RO_0002216 capable of part of http://purl.obolibrary.org/obo/RO_0002500 causal agent in c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. http://purl.obolibrary.org/obo/RO_0002410 causally related to http://purl.obolibrary.org/obo/RO_0002609 related via dependence to This relation groups causal relations between material entities and causal relations between processes http://purl.obolibrary.org/obo/RO_0002500 causal agent in http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process A relationship between a material entity and a process where the material entity has some causal role that influences the process http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. http://purl.obolibrary.org/obo/RO_0002608 has causal agent http://purl.obolibrary.org/obo/RO_0002410 causally related to Inverse of 'causal agent in' http://purl.obolibrary.org/obo/RO_0002203 develops into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/CLO_0037209 derived from cell http://purl.obolibrary.org/obo/RO_0001000 derives from http://purl.obolibrary.org/obo/IAO_0000039 has measurement unit label http://purl.obolibrary.org/obo/BFO_0000051 has part http://purl.obolibrary.org/obo/BFO_0000168 has specific dependent at all times http://purl.obolibrary.org/obo/BFO_0000125 has specific dependent at some time http://purl.obolibrary.org/obo/BFO_0000070 specifically depends on at all times http://purl.obolibrary.org/obo/BFO_0000169 specifically depends on at some time http://purl.obolibrary.org/obo/BFO_0000154 temporal projection of spatiotemporal http://purl.obolibrary.org/obo/BFO_0000157 during which exists http://purl.obolibrary.org/obo/BFO_0000156 has temporal occupant http://purl.obolibrary.org/obo/BFO_0000157 during which exists http://purl.obolibrary.org/obo/BFO_0000153 projects onto temporal region http://purl.obolibrary.org/obo/BFO_0000108 exists at http://purl.obolibrary.org/obo/BFO_0000155 occupies temporal region http://purl.obolibrary.org/obo/BFO_0000108 exists at http://purl.obolibrary.org/obo/RO_0000052 inheres in 'inheres in at all times' a relation between a specifically dependent continuant (the dependent) and an independent continuant (the bearer), in which the dependent specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000053 bearer of is bearer of a relation between an independent continuant (the bearer) and a specifically dependent continuant (the dependent), in which the dependent specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000056 participates in participates_in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000057 has participant has_participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000058 is concretized as concretized by at some time A relationship between a generically dependent continuant and a specifically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants. http://purl.obolibrary.org/obo/RO_0001000 derives_from derives_from a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0001001 derives into derives_into a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity http://purl.obolibrary.org/obo/RO_0002324 developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) http://purl.obolibrary.org/obo/OBI_0002135 has specified value A relation between a value specification and a literal. http://purl.obolibrary.org/obo/IAO_0000136 is about is_about is a (currently) primitive relation that relates an information artifact to an entity. http://purl.obolibrary.org/obo/IAO_0000417 is quality measured as inverse of the relation of is quality measurement of http://purl.obolibrary.org/obo/OBI_0000124 is_supported_by_data The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process http://purl.obolibrary.org/obo/OBI_0000417 achieves_planned_objective This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process. http://purl.obolibrary.org/obo/OBI_0000833 objective_achieved_by This relation obtains between a a objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process. http://purl.obolibrary.org/obo/RO_0000059 concretizes A relationship between a specifically dependent continuant and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant also depends on that same independent continuant. Multiple specifically dependent continuants can concretize the same generically dependent continuant. http://purl.obolibrary.org/obo/RO_0001025 located in a relation between two independent continuants, the target and the location, in which the target is entirely within the location http://purl.obolibrary.org/obo/BFO_0000117 has occurrent part b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001]) http://purl.obolibrary.org/obo/CLO_0000174 is in cell line repository an object property that specifies a cell line repository for a specifc cell line. http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A mereological relationship or a topological relationship http://purl.obolibrary.org/obo/BFO_0000132 part of occurrent [copied from inverse property 'has occurrent part'] b has_occurrent_part c = Def. c occurrent_part_of b. (axiom label in BFO2 Reference: [007-001]) http://purl.obolibrary.org/obo/BFO_0000176 part of continuant at some time [copied from inverse property 'has continuant part at some time'] b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) http://purl.obolibrary.org/obo/BFO_0000178 has continuant part at some time b has_continuant_part c at t = Def. c continuant_part_of b at t. (axiom label in BFO2 Reference: [006-001]) http://purl.obolibrary.org/obo/RO_0002609 related via dependence to A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes. http://purl.obolibrary.org/obo/BFO_0000054 realized in realized_in http://purl.obolibrary.org/obo/BFO_0000126 has spatiotemporal occupant http://purl.obolibrary.org/obo/BFO_0000130 occupies spatiotemporal region http://purl.obolibrary.org/obo/BFO_0000151 projects onto spatial region at some time http://purl.obolibrary.org/obo/BFO_0000152 spatial projection of spatiotemporal at some time http://purl.obolibrary.org/obo/BFO_0000055 realizes http://purl.obolibrary.org/obo/IAO_0000004 has measurement value http://purl.obolibrary.org/obo/BFO_0000083 occupies spatial region at some time http://purl.obolibrary.org/obo/BFO_0000123 has spatial occupant at some time http://purl.obolibrary.org/obo/BFO_0000086 has_quality http://purl.obolibrary.org/obo/BFO_0000125 has specific dependent at some time http://purl.obolibrary.org/obo/CLO_0000015 derives from patient having disease http://purl.obolibrary.org/obo/CLO_0000179 is disease model for http://www.ebi.ac.uk/efo/EFO_0000784 has_disease_location http://purl.obolibrary.org/obo/RO_0002222 temporal relation http://purl.obolibrary.org/obo/RO_0002328 functionally related to http://purl.obolibrary.org/obo/cl#lacks_plasma_membrane_part lacks_plasma_membrane_part http://purl.obolibrary.org/obo/BFO_0000169 specifically depends on at some time http://purl.obolibrary.org/obo/OSCI_0000008 date placed in storage http://purl.obolibrary.org/obo/OSCI_0000009 produced by http://purl.obolibrary.org/obo/OSCI_0000013 provided by http://purl.obolibrary.org/obo/BFO_0000058 concretized by at some time http://purl.obolibrary.org/obo/BFO_0000059 concretizes at some time http://purl.obolibrary.org/obo/BFO_0000157 during which exists http://purl.obolibrary.org/obo/BFO_0000108 exists at