Term IRI	Term label	Parent term IRI	Parent term label	Alternative term	Definition
http://purl.obolibrary.org/obo/OBI_0002465	age since culture seeding measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum	age of culture	An age measurement datum that is the result of the measurement of the age of a cell since cultured (the process of seeding cells onto a culture dish).
http://purl.obolibrary.org/obo/OBI_0002472	dbGaP study identifier	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol	dbGaP accession number	A central registered identifier symbol that denotes a specific study in dbGaP.
http://purl.obolibrary.org/obo/OBI_0002475	number of PCR cycles during library construction	http://purl.obolibrary.org/obo/IAO_0000027	data item	library construction PCR cycles	A data item that is the number of PCR cycles used during the construction of a sequencing library.
http://purl.obolibrary.org/obo/OBI_0002479	sequence read length measurement datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	read length, read length measurement datum	A measurement datum that is the result of the measurement of the number of bases in a DNA or RNA sequence.
http://purl.obolibrary.org/obo/OBI_0002480	sequencing library input quantity measurement datum	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum	library input amount	A scalar measurement datum that indicates the amount of sequencing library used as input for a sequencer.
http://purl.obolibrary.org/obo/OBI_0002482	specimen harvest quantity	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	harvest quantity	A scalar measurement datum that indicates the amount of specimen collected.
http://purl.obolibrary.org/obo/OBI_0002464	SRS identifier	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol	SRA sample accession number	An accession number that applies to a database record for an individual sample object in an NCBI Sequence Read Archive (SRA) submission. These records are imported from the NCBI BioSample database.
http://purl.obolibrary.org/obo/OBI_0002485	transcript analysis by single-end sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	transcript analysis by single-end sequencing	A sequencing assay that incorporates single-end reads and sequencing technology to determine transcripts, gene structures, and gene expressions.
http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module	http://purl.obolibrary.org/obo/IAO_8000000	ontology module	subset ontology	An ontology module that is extracted from a main ontology module and includes only a subset of entities or axioms.
http://purl.obolibrary.org/obo/OBI_0003250	biomedical laboratory organization	http://purl.obolibrary.org/obo/OBI_0000245	organization	laboratory	An organization that performs assays, processes specimens, analyses data and conducts planned processes relevant to the life sciences.
http://purl.obolibrary.org/obo/OBI_0002586	digital acquisition card	http://purl.obolibrary.org/obo/OBI_0000968	device	digital acquisition and digital generation card	The digital acquisition card acts as the interface between the computer and a measurement device via the computer bus. It converts the signal generated by a measurement device (output from device) to a digital signal via an analog-to-digital converter, ADC. It also converts a digital signal to an analog signal via a digital-to-analog converter, DAC. This analog signal (e.g., stimulus) is fed to a measurement device (input to device).
http://purl.obolibrary.org/obo/OBI_0002992	prevalence of pathogen in specimens	http://purl.obolibrary.org/obo/IAO_0000027	data item	prevalence of pathogen	A data item that is the frequency of detection of a specified pathogenic organism in collected specimens.
http://purl.obolibrary.org/obo/OBI_0002136	RNA Integrity Number calculation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	RIN calculation	A data transformation using the RIN algorithm to generate a quality measure of RNA based on features from an electrophoretic trace.
http://purl.obolibrary.org/obo/OBI_0002137	RNA Integrity Number value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification	RIN value specification	A value specification that specifies the value of the RNA Integrity Number as a real value between 1 (most degraded) and 10 (most intact).
http://purl.obolibrary.org/obo/OBI_0002142	Nanostring nCounter miRNA expression assay	http://purl.obolibrary.org/obo/OBI_0001926	microRNA profiling assay	microRNA counts	A microRNA profiling assay using digital molecular barcoding technology to quantify target microRNA molecules without the need for amplification.
http://purl.obolibrary.org/obo/OBI_0002143	bromouride labeling and sequencing after UV exposure	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	BruUV-seq	An RNA-seq assay to identify transcription start sites and active enhancer elements through isolation of bromouridine (Bru) labelled RNAs after UV light exposure introduces transcription-blocking lesions.
http://purl.obolibrary.org/obo/OBI_0002144	extrachromosomal circular DNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	circulome-seq	An assay which aims at identifying the endogenous population of extrachromosomal circular DNA originating from a subset of genomic loci and potentially having profound consequences on the regulatory and coding capabilities of these regions. The assay includes creation of a library out of the circular DNA molecules and subsequent sequencing using parallelized sequencing methods.
http://purl.obolibrary.org/obo/OBI_0002146	HIV antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	HIV I/II Ab assay	An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) antigens.
http://purl.obolibrary.org/obo/OBI_0002147	HIV group O antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	HIV I/II Plus O assay	An antigen specific antibodies assay that is meant to detect antibodies that bind to human immunodeficiency virus (HIV) group O antigens.
http://purl.obolibrary.org/obo/OBI_0002148	surface HBV antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	HBsAb assay	An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) surface antigens.
http://purl.obolibrary.org/obo/OBI_0002149	core HBV antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	HBcAb assay	An antigen specific antibodies assay that is meant to detect antibodies that bind to hepatitis B virus (HBV) core antigens.
http://purl.obolibrary.org/obo/OBI_0002150	core HBV IgM antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	HBcAb-IgM assay	An antigen specific antibodies assay that is meant to detectimmunoglobulin M (IgM) antibodies that bind to hepatitis B virus (HBV) core antigens.
http://purl.obolibrary.org/obo/OBI_0002151	HCV antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	HCV Ab assay	An antigen specific antibodies assay that is meant to detect antibodies that bind to Hepacivirus C (HCV) antigens.
http://purl.obolibrary.org/obo/OBI_0002152	EBV IgG antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	EBV IgG Ab assay	An antigen specific antibodies assay that is meant to detect immunoglobulin G (IgG) antibodies that bind to Epstein-Barr virus (EBV) antigens.
http://purl.obolibrary.org/obo/OBI_0002153	EBV IgM antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	EBV IgM Ab assay	An antigen specific antibodies assay that is meant to detect immunoglobulin M (IgM) antibodies that bind to Epstein-Barr virus (EBV) antigens.
http://purl.obolibrary.org/obo/OBI_0002154	CMV antibody assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	CMV Ab assay	An antigen specific antibodies assay that is meant to detect antibodies that bind to cytomegalovirus (CMV) antigens.
http://purl.obolibrary.org/obo/OBI_0002155	venereal disease research laboratory test	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	VDRL test	An analyte assay that is meant to detect general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. VDRL tests require a microscope and can be done on cerebrospinal fluid as well as blood.
http://purl.obolibrary.org/obo/OBI_0002156	rapid plasma reagin test	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	RPR assay	An analyte assay that is meant to detect with the aid of carbon or charcoal particles general antibodies that react with substances that are produced by cellular damage caused by Treponema pallidum indicating a syphilis infection. RPR tests can be done without a microscope.
http://purl.obolibrary.org/obo/OBI_0002157	HBV surface antigen assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	HBsAg assay	An analyte assay that is meant to detect hepatitis B virus (HBV) surface antigens.
http://purl.obolibrary.org/obo/OBI_0002158	HIV-1 nucleic acid testing	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	HIV-1 NAT	An analyte assay that is meant to detect human immunodeficiency virus (HIV-1) nucleic acids.
http://purl.obolibrary.org/obo/OBI_0002159	HCV nucleic acid testing	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	HCV NAT	An analyte assay that is meant to detect hepatitis C virus (HCV) nucleic acids.
http://purl.obolibrary.org/obo/OBI_0002160	multiplexed indexed T7 ChIP-seq assay	http://purl.obolibrary.org/obo/OBI_0000716	ChIP-seq assay	Mint-ChIP-seq	A ChIP-seq assay which leverages T7 promoter amplification to allow low sample input and chromatin barcoding and pool-and-split multiplexing for high-throughput, quantitative profiling of chromatin states.
http://purl.obolibrary.org/obo/OBI_0002161	systematic evolution of ligands by exponential enrichment assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay	SELEX	A binding assay that identifies protein-binding sites on nucleic acids by selecting high-affinity target ligands from a randomized pool. The process is repeated in rounds, then the bound nucleic acids are separated from the unbound nucleic acids and amplified by PCR._
http://purl.obolibrary.org/obo/OBI_0002171	dot blot assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	dot blot analysis	An analyte assay that detects molecules in a mixture dotted on a membrane using DNA probes or antibodies.
http://purl.obolibrary.org/obo/OBI_0002172	Northwestern blot assay	http://purl.obolibrary.org/obo/OBI_0001591	direct binding assay	Northwestern assay	A direct binding assay that detects interactions of labeled RNA with immobilized protein on a membrane.
http://purl.obolibrary.org/obo/OBI_0002175	ATP bioluminescence assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	cell viability ATP quantitation assay	An analyte assay that detects ATP concentration through light intensity when luciferase catalyzes the oxidation of luciferin in the presence of ATP, magnesium ions, and molecular oxygen.
http://purl.obolibrary.org/obo/OBI_0002183	two electrode voltage clamp assay	http://purl.obolibrary.org/obo/OBI_0002182	voltage clamp assay	TEVC	The two electrode voltage clamp (TEVC) method utilizes two low-resistance pipettes, one sensing voltage and the other injecting current. The microelectrodes are filled with conductive solution and inserted into the cell to artificially control membrane potential. The membrane acts as a dielectric as well as a resistor, while the fluids on either side of the membrane function as capacitors.[9] The microelectrodes compare the membrane potential against a command voltage, giving an accurate reproduction of the currents flowing across the membrane. Current readings can be used to analyze the electrical response of the cell to different applications. This technique is mainly used in the Oocyte preparation.
http://purl.obolibrary.org/obo/OBI_0002184	cut open oocyte voltage clamp assay	http://purl.obolibrary.org/obo/OBI_0002182	voltage clamp assay	COVG	The cut-open oocyte Vaseline gap (COVG) voltage-clamp technique is designed to solve weaknesses in the two elextrode voltage clamp by maximizing the benefits of the Xenopus oocyte expression system by improving on clamp speed, signal-to-noise ratio, and ability to effectively perfuse the oocyte. In this way, it was possible to combine the most popular transient expression system, and the associated benefits of molecular cloning and site-directed mutagenesis, with the superior voltage-clamp properties of cut-open cell techniques.
http://purl.obolibrary.org/obo/OBI_0002186	electroencephalography	http://purl.obolibrary.org/obo/OBI_0000454	extracellular electrophysiology recording assay	EEG	An extracellular electrophysiology assay where electrodes are mounted outside the brain (either on the surface of the scalp on onto the brain surface itself during surgery) to measure the electrical field over the external surface.
http://purl.obolibrary.org/obo/OBI_0003350	T2 weighted FSE  magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003348	T2 weighted magnetic resonance image data set	T2 weighted TSE magnetic resonance image data set	T2 weighted image collected using a fast/turbo spin echo sequence.
http://purl.obolibrary.org/obo/OBI_0003556	topical administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo	transcutaneous administration	An administration of a substance onto the surface of the skin of an organism.
http://purl.obolibrary.org/obo/OBI_0003570	intracarotid administration	http://purl.obolibrary.org/obo/OBI_0003561	intra-arterial administration	i.c. administration	An intra-arterial administration in which the substance is administered into the carotid artery.
http://purl.obolibrary.org/obo/OBI_0003575	scratching	http://purl.obolibrary.org/obo/BFO_0000015	process	abrading	A process in which the target material entity is scraped by another material entity.
http://purl.obolibrary.org/obo/OBI_0003687	m6A-MTase sequencing assay	http://purl.obolibrary.org/obo/OBI_0003686	chromatin accessibility assay	Fiber-seq	A DNA methylation profiling assay in which chromatin stencils are created by treating nuclei with m6A methyltransferase (MTase) and then sequenced using single-molecule circular consensus sequencing to identify regions of accessible DNA at nucleotide resolution.
http://purl.obolibrary.org/obo/OBI_0003739	manual muscle testing 8 score	http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item	MMT-8	A clinical data item that quantifies the muscle function of a person based on the person's ability to hold a series of eight body positions that target different muscle groups.
http://purl.obolibrary.org/obo/OBI_0003740	childhood myositis assessment scale score	http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item	CMAS	A clinical data item that quantifies the degree of muscle function in a child with myositis based on performance of 14 tasks associated with muscular strength and endurance.
http://purl.obolibrary.org/obo/OBI_0001970	multiplexed sequencing library	http://purl.obolibrary.org/obo/OBI_0000047	processed material	DNA-barcoded sequencing library	a multiplexed library is a material entity which is the output of a library preparation process that uses a ligation step to attach a unique multiplexing sequence identifier to a specific sample, then mixes several such tagged samples prior to the library amplification process proper. A multiplexed library allows the sequencing of several samples in one sequencing run.
http://purl.obolibrary.org/obo/OBI_0000014	regulator role	http://purl.obolibrary.org/obo/OBI_0000017	regulatory role	regulator	a regulatory role involved with making and/or enforcing relevant legislation and governmental orders
http://purl.obolibrary.org/obo/OBI_0000018	material supplier role	http://purl.obolibrary.org/obo/OBI_0000947	service provider role	material provider role	a role realized through the process of supplying materials such as animal subjects, reagents or other materials used in an investigation.
http://purl.obolibrary.org/obo/OBI_0000020	contract research organization role	http://purl.obolibrary.org/obo/OBI_0000116	worker role	contract research organization	a worker role of carrying out the study according to the protocol document or study plan delivered by the PI, under the control of the study director.  This role cannot make decisions about the study execution
http://purl.obolibrary.org/obo/OBI_0000023	classified data set	http://purl.obolibrary.org/obo/IAO_0000100	data set	data set with assigned class labels	A data set that is produced as the output of a class prediction data transformation and consists of a data set with assigned class labels.
http://purl.obolibrary.org/obo/OBI_0000025	reference substance role	http://purl.obolibrary.org/obo/BFO_0000023	role	reference substance	a role inhering in a material entity that is realized when  characteristics or responses elicited by the substance are used for comparison or reference.
http://purl.obolibrary.org/obo/OBI_0000026	cytological stain role	http://purl.obolibrary.org/obo/OBI_0000250	dye role	cytological stain	A dye role that is realized when the stain is used to colour cells and or cellular components for the purposes of visualization
http://purl.obolibrary.org/obo/OBI_0000032	clinical research coordinator role	http://purl.obolibrary.org/obo/OBI_0000116	worker role	clinical research coordinator	a worker role comprised of handling the administrative duties of a trial or study.
http://purl.obolibrary.org/obo/OBI_0000040	drug role	http://purl.obolibrary.org/obo/BFO_0000023	role	drug	a role borne by a molecular entity and is realized in a process of absorption by an organism  alters, or effects  (or is assumed to effect) a function(s) which inhere in an organism
http://purl.obolibrary.org/obo/OBI_0000048	chromatography device	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control	chromatography instrument	A device that facilitates the separation of mixtures. The function of a chromatography device involves passing a mixture dissolved in a "mobile phase" through a stationary phase, which separates the analyte to be measured from other molecules in the mixture and allows it to be isolated.
http://purl.obolibrary.org/obo/OBI_0000056	notified body role	http://purl.obolibrary.org/obo/OBI_0000273	role of regulator of consumables and medical devices	notified body	Notified body is regulator of consumables and medical devices charged by the Competent Authority with verifying compliance of medical devices (not drugs) with the applicable Essential Requirements stated in the Medical Device Directive
http://purl.obolibrary.org/obo/OBI_0000060	trial monitor role	http://purl.obolibrary.org/obo/OBI_0000102	responsible party role	trial monitor	a responsible party involved in planning, overseeing the conduct of a study or study component, and interpreting data from a study
http://purl.obolibrary.org/obo/OBI_0000064	positive reference substance role	http://purl.obolibrary.org/obo/OBI_0000025	reference substance role	positive reference substance	a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a "100%" response
http://purl.obolibrary.org/obo/OBI_0000068	reporting party role	http://purl.obolibrary.org/obo/OBI_0000202	investigation agent role	submitter	a study personnel role played by a party who reports the outcome of a study component
http://purl.obolibrary.org/obo/OBI_0000070	assay	http://purl.obolibrary.org/obo/OBI_0000011	planned process	scientific observation	A planned process that has the objective to produce information about a material entity (the evaluant) by examining it.
http://purl.obolibrary.org/obo/OBI_0000073	sample preparation for assay	http://purl.obolibrary.org/obo/OBI_0000094	material processing	study	A sample_preparation_for_assay is a protocol_application including material_enrollments and biomaterial_transformations. definition_source: OBI.
http://purl.obolibrary.org/obo/OBI_0000086	reagent role	http://purl.obolibrary.org/obo/OBI_0003610	reactant role	reagent	A role inhering in a biological or chemical entity that is intended to be applied in a scientific technique to participate (or have molecular components that participate) in a chemical reaction that facilitates the generation of data about some entity distinct from the bearer, or the generation of some specified material output distinct from the bearer.
http://purl.obolibrary.org/obo/OBI_0000089	role of regulator of chemical manufacturer	http://purl.obolibrary.org/obo/OBI_0000014	regulator role	regulator of chemical manufacture	a regulator involved with making and enforcing legislation and governmental orders relevant to chemical manufacture
http://purl.obolibrary.org/obo/OBI_0000092	role of certified IRB professional	http://purl.obolibrary.org/obo/OBI_0000016	regulation-assigned role	certified IRB professional	a role of which inheres in a Homo sapiens and realized during administration and oversight of the daily activities of Institutional Review Boards (IRBs) in the USA
http://purl.obolibrary.org/obo/OBI_0000093	patient role	http://purl.obolibrary.org/obo/BFO_0000023	role	patient	a role which inheres in a person and is realized by the process of being under the care of a physician or health care provider
http://purl.obolibrary.org/obo/OBI_0000094	material processing	http://purl.obolibrary.org/obo/OBI_0000011	planned process	material transformation	A planned process which results in physical changes in a specified input material
http://purl.obolibrary.org/obo/OBI_0000102	responsible party role	http://purl.obolibrary.org/obo/OBI_0000202	investigation agent role	responsible party	a study personnel role played by a party who is accountable for the execution of a study component and can make decisions about the conduct of the study
http://purl.obolibrary.org/obo/OBI_0000103	principal investigator role	http://purl.obolibrary.org/obo/OBI_0000102	responsible party role	principal investigator	a responsible party role played by a person responsible for the overall conduct of a study
http://purl.obolibrary.org/obo/OBI_0000110	pH indicator dye role	http://purl.obolibrary.org/obo/OBI_0000250	dye role	pH indicator dye	the role of a dye that is realized when the dye is used in an experiment to measure the pH in a material entity
http://purl.obolibrary.org/obo/OBI_0000116	worker role	http://purl.obolibrary.org/obo/OBI_0000202	investigation agent role	worker	a personnel role played by a party who executes a component of the study plan; this can occur before, during, after or outside the study timeline
http://purl.obolibrary.org/obo/OBI_0000140	obsolete_label role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	label	Label role is a role which inheres in a material entity and which is realized in a detection of label assay
http://purl.obolibrary.org/obo/OBI_0000143	baseline participant role	http://purl.obolibrary.org/obo/OBI_0000220	reference subject role	baseline participant	a reference participant role which is realized by making the reference to qualities at the start of the study or intervention
http://purl.obolibrary.org/obo/OBI_0000144	role of independent data monitoring committee	http://purl.obolibrary.org/obo/OBI_0000060	trial monitor role	independent data monitoring committee	a trial monitor role charged recommending whether to continue, modify, or end the trial
http://purl.obolibrary.org/obo/OBI_0000145	pathologist role	http://purl.obolibrary.org/obo/OBI_0000116	worker role	Pathologist	a worker role of being responsible for making the histopathology diagnoses associated with data from a study; this activity occurs outside the study timeline
http://purl.obolibrary.org/obo/OBI_0000154	role of Institutional Review Board	http://purl.obolibrary.org/obo/OBI_0000014	regulator role	Internal Review Board	the role of a organization that is realized by members reviewing study designs for their agreement with regulations
http://purl.obolibrary.org/obo/OBI_0000161	crossover population role	http://purl.obolibrary.org/obo/OBI_0000220	reference subject role	crossover population	a role realized when a participant serves as reference to itself
http://purl.obolibrary.org/obo/OBI_0000162	complete nutrient role	http://purl.obolibrary.org/obo/OBI_0000204	nutrient role	complete nutrient	A nutrient role that inheres in a material entity and is realized in the use of that material entity by an organism to provide all needed nourishment.
http://purl.obolibrary.org/obo/OBI_0000163	radiolabel role	http://purl.obolibrary.org/obo/OBI_0002743	molecular label role	radiolabel	a molecular label role which inheres in a material entity which is realized by the process of radioactivity detection
http://purl.obolibrary.org/obo/OBI_0000169	placebo role	http://purl.obolibrary.org/obo/OBI_0000214	negative reference substance role	placebo	a negative reference substance is a reference role in which the substance playing the reference substance role is physically similar in appearance to the test substance
http://purl.obolibrary.org/obo/OBI_0000174	study group role	http://purl.obolibrary.org/obo/BFO_0000023	role	study group population	a study population role where the bearer is a population of material entities and the role is realized in the implementation of a study design wherein the entities bearing the study population role are observed or subjected to intervention according to the study design and are biological replicates, i.e. they receive the same treatment under the protocol
http://purl.obolibrary.org/obo/OBI_0000188	role of pathology review board	http://purl.obolibrary.org/obo/OBI_0000116	worker role	pathology review board	a worker role comprised of providing a confirmed and consensus diagnosis for histopathology results obtained during the investigation
http://purl.obolibrary.org/obo/OBI_0000192	microtiter plate	http://purl.obolibrary.org/obo/OBI_0000967	container	microplate	A microtiter_plate is a flat plate with multiple wells used as small test tubes.
http://purl.obolibrary.org/obo/OBI_0000196	role of impartial witness	http://purl.obolibrary.org/obo/OBI_0000016	regulation-assigned role	impartial witness	a role which inheres in a Homo sapiens and is realized during a clinical trial - the impartial witness is independent of the trial and cannot be unfairly influenced by people involved with the trial
http://purl.obolibrary.org/obo/OBI_00001975	chromatin immunoprecipitation	http://purl.obolibrary.org/obo/OBI_0000690	immunoprecipitation	ChIP	An immunoprecipitation in which chromatin (i.e. packaged DNA which can include protein and RNA complexes) is cut into short regions, reversibly cross linked, and antibodies or tags are used to select for pieces of chromatin with desired characteristics.
http://purl.obolibrary.org/obo/OBI_0000198	biological replicate role	http://purl.obolibrary.org/obo/OBI_0000220	reference subject role	biological replicate	a reference participant role realized by equivalent treatment of participants
http://purl.obolibrary.org/obo/OBI_0000202	investigation agent role	http://purl.obolibrary.org/obo/BFO_0000023	role	investigator	A role borne by an entity and that is realized in a process that is part of an investigation in which an objective is achieved. These processes include, among others: planning, overseeing, funding, reviewing.
http://purl.obolibrary.org/obo/OBI_0000204	nutrient role	http://purl.obolibrary.org/obo/BFO_0000023	role	nutrient	a role that inheres in a material entity and is realized in the use of that material entity by an organism when it is used in that organism's metabolism and provides nourishment.
http://purl.obolibrary.org/obo/OBI_0000207	obsolete health care provider role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	health care provider	a worker role of providing medical care either within or outside the study timeline
http://purl.obolibrary.org/obo/OBI_0000211	proxy respondent role	http://purl.obolibrary.org/obo/OBI_0000116	worker role	proxy respondent	Proxy respondent is a worker role of describing patient's symptoms or condition to medical personnel
http://purl.obolibrary.org/obo/OBI_0000214	negative reference substance role	http://purl.obolibrary.org/obo/OBI_0000025	reference substance role	negative reference substance	a reference role in which the characteristics or responses elicited by the substance playing the reference substance role are used to establish a "no effect" response
http://purl.obolibrary.org/obo/OBI_0000215	role of legally acceptable representative	http://purl.obolibrary.org/obo/OBI_0000016	regulation-assigned role	legally acceptable representative	a role which inheres in a human or organization who are able subject to applicable law to consent, on behalf of a prospective subject, to the subject`s participation in as clinical trial.
http://purl.obolibrary.org/obo/OBI_0000220	reference subject role	http://purl.obolibrary.org/obo/OBI_0000097	participant under investigation role	reference participant	a reference subject  role which inheres in an organism or entity of organismal origin so that the characteristics or responses of the participant playing the reference participant role are used for comparison or reference
http://purl.obolibrary.org/obo/OBI_0000221	vital dye role	http://purl.obolibrary.org/obo/OBI_0000250	dye role	vital dye	A dye role that is realized when used to detect live cells in an experiment
http://purl.obolibrary.org/obo/OBI_0000224	sub-investigator role	http://purl.obolibrary.org/obo/OBI_0000116	worker role	sub-investigator	a worker role authorized to make study-related decisions and carry out tasks related to the study; this role occurs during the study timeline
http://purl.obolibrary.org/obo/OBI_0000234	trial statistician role	http://purl.obolibrary.org/obo/OBI_0000116	worker role	trial statistician	a worker role that analyzes data obtained during a trial or study; this role occurs after the trial or study is completed or terminated.
http://purl.obolibrary.org/obo/OBI_0000243	sponsor role	http://purl.obolibrary.org/obo/OBI_0000102	responsible party role	sponsor	a responsible party role involved with any of the following activities:  initiating, managing and funding a study
http://purl.obolibrary.org/obo/OBI_0000248	feed role	http://purl.obolibrary.org/obo/OBI_0000162	complete nutrient role	feed	a role that inheres in a material entity and is realized in the use of that material entity by lab animal to provide all needed nourishment.
http://purl.obolibrary.org/obo/OBI_0000249	technical replicate role	http://purl.obolibrary.org/obo/OBI_0000220	reference subject role	technical replicate	technical replicate role is realized when two portions from one evaluant are used in replicate runs of an assay
http://purl.obolibrary.org/obo/OBI_0000250	dye role	http://purl.obolibrary.org/obo/OBI_0002743	molecular label role	dye	A molecular label role which inheres in a material entity and which is realized in the process of detecting a molecular dye that imparts color to some material of interest.
http://purl.obolibrary.org/obo/OBI_0000264	obsolete_sample population	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	recruited population	A sample population is an object aggregate that is selected from the population, e.g. the fish in the net that were sampled from the lake, the people that responded to the call for volunteers.
http://purl.obolibrary.org/obo/OBI_0000273	role of regulator of consumables and medical devices	http://purl.obolibrary.org/obo/OBI_0000014	regulator role	drug regulatoy authority	a regulator involved with making and enforcing legislation and governmental orders relevant to the development, testing, manufacture and use of food, drugs and medical devices
http://purl.obolibrary.org/obo/OBI_0000286	precipitate	http://purl.obolibrary.org/obo/OBI_0000047	processed material	precipited material	a precipitate is a material entity which is output of a precipitation process
http://purl.obolibrary.org/obo/OBI_0000291	transcription factor binding site assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay	TF binding	An assay tthat determines DNA regions specifically recognized by proteins that function as transcription factors
http://purl.obolibrary.org/obo/OBI_0000318	eluate	http://purl.obolibrary.org/obo/OBI_0000047	processed material	eluted material	a eluate is a material entity which results from an elution, e.g. from a chromatography column. it has as part a material entity with role mobile phase
http://purl.obolibrary.org/obo/OBI_0000366	metabolite profiling assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	metabolomic assay	An assay that detects and identifies chemical entities resulting from biochemical and cellular metabolism
http://purl.obolibrary.org/obo/OBI_0000384	electricity supply function	http://purl.obolibrary.org/obo/OBI_0000391	energy supply function	power supply	An electricity supply function is an energy supply function to transfer electricity from one source to another, typically a consumer of the electricity or as a stimulus during a neuroscience experiment.
http://purl.obolibrary.org/obo/OBI_0000389	isoelectric focusing device	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control	isoelectric focusing unit	An isoelectric focusing device is a device in which isoelectric focusing can be performed. An isoelectric focussing device had the function to contain and control the contained environment and transfer electrical energy from a power supply to a separation medium and the charged material to be separated.
http://purl.obolibrary.org/obo/OBI_0000392	information processor function	http://purl.obolibrary.org/obo/BFO_0000034	function	data processor function	An information processor function is a function that converts information from one form to another, by a lossless process or an extraction process.
http://purl.obolibrary.org/obo/OBI_0000393	signal conversion function	http://purl.obolibrary.org/obo/OBI_0000392	information processor function	transduction function	A signal conversion function is an information processor function which transforms a signal into another type of signal. For example an analog-to-digital_converter, Ac/Ac converter, a synapse converts electrical action potentials into an intermediate chemical signal. The post synapse converts it back into an electric one passed on to the axon.
http://purl.obolibrary.org/obo/OBI_0000398	image creation device	http://purl.obolibrary.org/obo/OBI_0000832	measurement device	image acquisition device	An image creation device is a device which captures a digitized image of an object
http://purl.obolibrary.org/obo/OBI_0000415	polymerase chain reaction	http://purl.obolibrary.org/obo/OBI_0600058	enzymatic amplification	PCR	PCR is the process in which a DNA polymerase is used to amplify a piece of DNA by in vitro enzymatic replication. As PCR progresses, the DNA thus generated is itself used as a template for replication. This sets in motion a chain reaction in which the DNA template is exponentially amplified.
http://purl.obolibrary.org/obo/OBI_0000423	extract	http://purl.obolibrary.org/obo/OBI_0000047	processed material	extracted material	an extract is a material entity which results from an extraction process
http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	transcription profiling	An assay that determines gene expression and transcription activity using ribonucleic acids collected from a material entity.
http://purl.obolibrary.org/obo/OBI_0000435	genotyping assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	genotype profiling	An assay which generates data about a genotype from a specimen of genomic DNA. A variety of techniques and instruments can be used to produce information about sequence variation at particular genomic positions.
http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification	artifact  creation objective	an objective specifiction that creates an specific output object from input materials.
http://purl.obolibrary.org/obo/OBI_0000466	thermal conductivity detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	TCD, hot wire detector	The most commonly used detector in preparative GC is the thermal conductivity detector (hot wire detector). Even this detector, however, is often too sensitive and has too high a flow impedance. Under such circumstances, the procedure mentioned above must be employed. The eluent from the preparative column is split and a small portion diverted through the detector (sometimes with further dilution with carrier gas to reduce sensitivity).
http://purl.obolibrary.org/obo/OBI_0000480	Bruker high resolution probe	http://purl.obolibrary.org/obo/OBI_0000561	Bruker NMR probe	HR Probe	BRUKER BIOSPIN's experienced Research & Development group not only delivers top-performance probes for the more common experiments, but also a wealth of special probes for almost any application. For high resolution (HR) NMR we offer probes with a variety of important characteristics and features.
http://purl.obolibrary.org/obo/OBI_0000506	photoionization detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	PID	The selective determination of aromatic hydrocarbons or organo-heteroatom species is the job of the photoionization detector (PID). This device uses ultraviolet light as a means of ionizing an analyte exiting from a GC column. The ions produced by this process are collected by electrodes. The current generated is therefore a measure of the analyte concentration. f the amount of ionization is reproducible for a given compound, pressure, and light source then the current collected at the PID's reaction cell electrodes is reproducibly proportional to the amount of that compound entering the cell. The reason why the compounds that are routinely analyzed are either aromatic hydrocarbons or heteroatom containing compounds (like organosulfur or organophosphorus species) is because these species have ionization potentials (IP) that are within reach of commercially available UV lamps. The available lamp energies range from 8.3 to 11.7 ev, that is, lambda max ranging from 150 nm to 106 nm. Although most PIDs have only one lamp, lamps in the PID are exchanged depending on the compound selectivity required in the analysis.
http://purl.obolibrary.org/obo/OBI_0000509	electron capture detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	ECD	The electron capture detector is a GC detector that uses a radioactive Beta emitter (electrons) to ionize some of the carrier gas and produce a current between a biased pair of electrodes. When organic molecules that contain electronegative functional groups, such as halogens, phosphorous, and nitro groups pass by the detector, they capture some of the electrons and reduce the current measured between the electrodes.
http://purl.obolibrary.org/obo/OBI_0000520	clinical chemistry assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	detection of analyte in blood sample	An analyte assay which uses analytical methods to produce measurements and data on the concentration of chemical parameters (analytes) present in a bodily fluid collected from an organism.
http://purl.obolibrary.org/obo/OBI_0000521	flame ionization detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	FID	A flame ionization detector is a GC detector that consist of a hydrogen/air flame and a collector plate which are normally heated independently of the chromatographic oven. Heating is necessary in order to prevent condensation of water generated by the flame and also to prevent any hold-up of solutes as they pass from the column to the flame. There is an electrode above the flame to collect the ions formed at a hydrogen/air flame. The number of ions hitting the collector is measured and a signal is generated. Flame ionization detectors are most widely used and generally applicable for gas chromatography and hence is used for routine and general purpose analysis. It is easy to use but destructive of the sample.
http://purl.obolibrary.org/obo/OBI_0000523	magic angle spinning rotor	http://purl.obolibrary.org/obo/OBI_0000968	device	MAS rotor	A rotor device that holds the NMR sample and enables the adjustment of the orientation of the rotation axis for a sample in a NMR instrument in the magic angle.
http://purl.obolibrary.org/obo/OBI_0000527	flow high resolution probe	http://purl.obolibrary.org/obo/OBI_0000480	Bruker high resolution probe	flow HR-probe	Hyphenated analytical techniques combining mass spectrometry and chromatography are well-established laboratory tools. The combination of chromatography and NMR has also made its way into the analytical laboratory. Further developments even combine all three techniques into an LC-NMR/NMR-MS system. The use of solid phase extraction provides an efficient interface between chromatography and NMR with demands for special type of flow probes.
http://purl.obolibrary.org/obo/OBI_0000537	copy number variation profiling assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	CNV analysis	An assay that determines lost or amplified genomic regions of DNA by comparing genomic DNA originating from tissues from the same or different individuals using specific techniques such as CGH, array CGH, SNP genotyping
http://purl.obolibrary.org/obo/OBI_0000552	reverse transcribed polymerase chain reaction	http://purl.obolibrary.org/obo/OBI_0600058	enzymatic amplification	reverse transcription polymerase chain reaction	reverse transcribe pcr is a process which allow amplification of cDNA during a pcr reaction while the cDNA results from a retrotranscription of messenger RNA isolated from a material entity.
http://purl.obolibrary.org/obo/OBI_0000566	NMR instrument	http://purl.obolibrary.org/obo/OBI_0000832	measurement device	magnetic resonance imaging scanner	An Instrument which is used to carry out a NMR analysis of some sample.
http://purl.obolibrary.org/obo/OBI_0000569	mass selective detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	mass spectrometry detector	A mass selective detector is a GC detector that uses mass spectrometry. It is based upon the ionization of solute molecules in the ion source and the separation of the ions generated on the basis of their mass/charge ratio by an analyzer unit. This may be a magnetic sector analyzer, a quadruple mass filter, or an ion trap. Ions are detected by a dynode electron multiplier.
http://purl.obolibrary.org/obo/OBI_0000576	scattered molecular aggregate	http://purl.obolibrary.org/obo/BFO_0000040	material entity	Collective	a material entity that consists of all the molecules of a specific type that are located in some bounded region and which is part of a more massive material entity that has parts that are other such aggregates
http://purl.obolibrary.org/obo/OBI_0000588	flame photometric detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	FPD	The determination of sulfur or phosphorus containing compounds is the job of the flame photometric detector (FPD). This device uses the chemiluminescent reactions of these compounds in a hydrogen/air flame as a source of analytical information that is relatively specific for substances containing these two kinds of atoms. The emitting species for sulfur compounds is excited S2. The lambda max for emission of excited S2 is approximately 394 nm. The emitter for phosphorus compounds in the flame is excited HPO (lambda max = doublet 510-526 nm). In order to selectively detect one or the other family of compounds as it elutes from the GC column, an interference filter is used between the flame and the photomultiplier tube (PMT) to isolate the appropriate emission band. The drawback here being that the filter must be exchanged between chromatographic runs if the other family of compounds is to be detected.
http://purl.obolibrary.org/obo/OBI_0000591	Bruker BEST NMR system	http://purl.obolibrary.org/obo/OBI_0000464	Bruker autosampler	Bruker Efficient Sample Transfer NMR	The introduction of biological screening and combinatorial chemistry for chemical synthesis has also introduced new requirements for NMR automation, e.g., the use of well plates for sample input, increased demands on throughput, and the need for quick and simple interpretation of the acquired NMR data.
http://purl.obolibrary.org/obo/OBI_0000595	pulsed amperometric detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device	PAD	A chromatography detector as used by high-performance anion exchange chromatography that provides sensitive and specific detection of carbohydrates. Pulsed Electrochemical Detection (PED) allows simple, sensitive, and direct detection of numerous polar aliphatic compounds, especially carbohydrates. This technique exploits the electrocatalytic activity of noble metal electrode surfaces to oxidize various polar functional groups. In PED, multi-step potential-time waveforms at Au and Pt electrodes realize amperometric/coulometric detection while maintaining uniform and reproducible electrode activity. The response mechanisms in PED are dominated by the surface properties of the electrode, and, as a consequence, members of each chemical class of compounds produce virtually identical voltammetric responses. Thus, the full potential is realized when combined with high performance liquid chromatography (HPLC).
http://purl.obolibrary.org/obo/OBI_0000607	high resolution magic angle spin probe	http://purl.obolibrary.org/obo/OBI_0000480	Bruker high resolution probe	high resolution MAS, hr-MAS	Samples that are neither solid nor liquid, being of biological, chemical, or pharmaceutical interest, reveal highly resolved spectra when magic angle spinning is applied. The correct solution is a gradient, such that the field varies along the spinner axis. This so-called Magic Angle Gradient is employed in Brukers high resolution Magic Angle Spinning (hr-MAS) probes, and is implemented in such a way that it is compatible with the stator and does not interfere with the sample eject or insert. Bruker BioSpin has developed a series of dedicated probes for standard bore magnets to accommodate the rapidly expanding field of hr-MAS. These probes are available in double (e.g. 1H and 13C) and triple resonance (e.g. 1H, 13C, 15N) modes and come equipped with a deuterium lock channel. The probes have automatic sample ejection and insertion capability, with the availability of an optional sample changer, enabling fully automated sample runs. Probes can be equipped with an optional B0 gradient, directed along the magic angle, so that gradient spectroscopy can be done used.
http://purl.obolibrary.org/obo/OBI_0000612	Bruker MATCH tube holder system	http://purl.obolibrary.org/obo/OBI_0000484	NMR sample holder	Bruker Multiple Adjustable Tube Clamp Holder	The Bruker Multiple Adjustable Tube Clamp Holder MATCH system is a holder for 100 mm long NMR sample tubes with diameters ranging from micro tubes up to 5 mm NMR tubes. The MATCH insert fits into a standard 10 mm Bruker spinner and is suitable for all non-spinning applications.n   The MATCH system provides an easy and cost efficient means of optimizing the signal-to-noise ratio of each sample. By matching the NMR tube diameter to the size of the sample, most of the sample can be placed in the active column of the NMR coil. This leads to an enhanced signal detection compared to diluting the same sample quantity in a larger tube.
http://purl.obolibrary.org/obo/OBI_0000615	protein expression profiling assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	proteomic analysis	An assay that determines protein expression and translation activity using protein extracts collected from a material entity.
http://purl.obolibrary.org/obo/OBI_0000616	high resolution probe with automatic tuning and matching	http://purl.obolibrary.org/obo/OBI_0000480	Bruker high resolution probe	High Resolution Probes with Automatic Tuning and Matching, HR_probe_with_ATM	The Automatic Tuning and Matching (ATM) option for AVANCE spectrometers is available for double resonance probes in fixed-frequency and broadband tunable configurations with either direct or indirect detection. Thus, for multinuclear operation, as often required for applications in inorganic chemistry, ATM facilitates the accurate setting of 90 degree pulse widths on both observe and decoupling channels for each chosen nucleus and each individual sample - even with full automation. Triple resonance probes in fixed-frequency configurations, as typically used for inverse detection with high-field systems.
http://purl.obolibrary.org/obo/OBI_0000623	NMR spectroscopy assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	Nuclear magnetic resonance spectroscopy	An assay that exploits the magnetic properties of certain nuclei (those with a spin) to resonate when placed in particular magnetic field conditions. Instruments recording NMR spectrum and sets of analysis can be used to deduce identity of chemical as well as composition of complex chemical mixtures.
http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	nucleotide sequencing	A sequencing assay which determines information on the sequence of a DNA molecule.
http://purl.obolibrary.org/obo/OBI_0000629	Bruker solid magic angle spinning probe	http://purl.obolibrary.org/obo/OBI_0000561	Bruker NMR probe	solid MAS probe	Magic angle spinning, nowadays a routine technique for solids NMR, still offers the capability of innovation. The high mechanical performance of MAS probes in conjunction with efficient rf pulse techniques open new exciting fields in solids NMR of biological samples and in the field of quadrupolar nuclei.
http://purl.obolibrary.org/obo/OBI_0000630	hematology assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	haematology	An assay that studies blood and blood producing organs using a variety of techniques and instruments
http://purl.obolibrary.org/obo/OBI_0000634	DNA methylation profiling assay	http://purl.obolibrary.org/obo/OBI_0002020	epigenetic modification assay	DNA methylation profiling	An assay that measures the state of methylation of DNA molecules using genomic DNA collected from a material entity using a range of techniques and instrument such as DNA sequencers and often relying on treatment with bisulfites to ensure cytosine conversion.
http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	http://purl.obolibrary.org/obo/OBI_0000481	chromatography detector	FID	A gas chromatography detector is a chromatography detector that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a gas chromatographic process and thus permits the senses to appreciate the nature of the separation. There is no LC detector that has an equivalent performance to the flame ionization detector (FID) used in GC. In general, LC detectors have sensitivities of two to three orders of magnitude less than their GC counterparts and linear dynamic ranges one to two orders of magnitude lower. Only highly specific LC detectors have sensitivities that can approach those of GC detectors.
http://purl.obolibrary.org/obo/OBI_0000642	atomic emission detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector	AED	Instead of measuring simple gas phase (carbon containing) ions created in a flame as with the flame ionization detector, or the change in background current because of electronegative element capture of thermal electrons as with the electron capture detector, the AED has a much wider applicability because it is based on the detection of atomic emissions. The strength of the AED lies in the detector's ability to simultaneously determine the atomic emissions of many of the elements in analytes that elute from a GC capillary column (called eluants or solutes in some books). As eluants come off the capillary column they are fed into a microwave powered plasma (or discharge) cavity where the compounds are destroyed and their atoms are excited by the energy of the plasma. The light that is emitted by the excited particles is separated into individual lines via a photodiode array. The associated computer then sorts out the individual emission lines and can produce chromatograms made up of peaks from eluants that contain only a specific element.
http://purl.obolibrary.org/obo/OBI_0000648	clustered data set	http://purl.obolibrary.org/obo/IAO_0000100	data set	data set with assigned discovered class labels	A data set that is produced as the output of a class discovery data transformation and consists of a data set with assigned discovered class labels.
http://purl.obolibrary.org/obo/OBI_0000658	data representational model	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	data structure specification	An information content entity representing the relationships between data items.
http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process	http://purl.obolibrary.org/obo/OBI_0000011	planned process	specimen collection	A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed.
http://purl.obolibrary.org/obo/OBI_0000661	enzyme-linked immunosorbent assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	ELISA	An analyte assay where binding of an enzyme linked antibody to a material entity that is immobilized on solid support is detected utilizing a chemiluminescent reaction. Depending on the setup, the enzyme-linked antibody could be binding directly to the analyte, or it serves as a secondary antibody detecting binding of the primary antibody to the analyte.
http://purl.obolibrary.org/obo/OBI_0000663	class prediction data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	supervised classification data transformation	A class prediction data transformation (sometimes called supervised classification) is a data transformation that has objective class prediction.
http://purl.obolibrary.org/obo/OBI_0000665	obsolete intracellular cytokine staining assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	ICS	The measurement of cytokines within the cytoplasm of a cell by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0000667	obsolete MHC multimer staining assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	MHC tetramer assay	An MHC multimer assay is an assay that detects T cells capable of binding the MHC:ligand complexes present in the multimer. The multimer is fluorescently labelled. The T cells bound to multimers are counted in a flow cytometer
http://purl.obolibrary.org/obo/OBI_0000674	center value	http://purl.obolibrary.org/obo/IAO_0000027	data item	median	A data item that is produced as the output of a center calculation data transformation and represents the center value of the input data.
http://purl.obolibrary.org/obo/OBI_0000675	statistical hypothesis test objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	hypothesis test objective	is a data transformation objective where the aim is to estimate statistical significance with the aim of proving or disproving a hypothesis by means of some data transformation.
http://purl.obolibrary.org/obo/OBI_0000679	average value	http://purl.obolibrary.org/obo/IAO_0000027	data item	arithmetic mean	A  data item that is produced as the output of an averaging data transformation and represents the average value of the input data.
http://purl.obolibrary.org/obo/OBI_0000689	454 Genome Sequence 20	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	GS 20	is a DNA sequencer first manufactured by 454 Life Science Corporation in 2005, and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information.
http://purl.obolibrary.org/obo/OBI_0000693	MeDIP-seq assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	Methylated DNA immunoprecipitation sequencing assay	A DNA methylation profiling assay that identifies methylated sites in genomic DNA and determines the methylation pattern that affect gene transcription using immunoprecipitation of methylated genomic DNA, creation of a library of corresponding DNA fragments (either single or paired-end fragments) and subsequent sequencing using parallelized sequencing methods.
http://purl.obolibrary.org/obo/OBI_0000695	chain termination sequencing assay	http://purl.obolibrary.org/obo/OBI_0000734	DNA sequencing by synthesis assay	dye terminator sequencing	A DNA sequencing assay which rely on the use of dideoxynucleotides used in 4 distinct sequencing reaction on the same DNA sample. The dideoxynucleotides, once incorporated in the complementary DNA strand being synthesized by the DNA polymerase prevent any further chain elongation. The newly generated sequences are resolved on a polyacrylamide gel using electrophoresis and labels (either fluorochrome or radioactivity) are used to determine the nucleotide present at a given position
http://purl.obolibrary.org/obo/OBI_0000697	Helicos sequencing assay	http://purl.obolibrary.org/obo/OBI_0000734	DNA sequencing by synthesis assay	true single molecule sequencing	A DNA sequencing by synthesis assay that identifiies the sequnece of billions of DNA molecules immobilized to a surface using DNA polymerase and fluorescently labeled nucleotides added one at a time. The sequencing process does not require an amplification step and is typically able to produce reads of 25 base pair length.
http://purl.obolibrary.org/obo/OBI_0000698	obsolete_DNA ligase	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	ligase	A DNA ligase is an enzyme that covalently joins two compatible pieces of DNA through the cleavage of an ATP molecule
http://purl.obolibrary.org/obo/OBI_0000700	support vector machine	http://purl.obolibrary.org/obo/OBI_0000663	class prediction data transformation	SVM	A support vector machine is a data transformation with a class prediction objective based on the construction of a separating hyperplane that maximizes the margin between two data sets of vectors in n-dimensional space.
http://purl.obolibrary.org/obo/OBI_0000701	self-organizing map	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation	SOM	A self-organizing map (SOM) is an artificial neural network with objective class discovery that uses a neighborhood function to preserve the topological properties of a dataset to produce low-dimensional (typically 2) discretized representation of the training data set. A set of artificial neurons learn to map points in an input space to coordinates in an output space. The input space can have different dimensions and topology from the output space, and the SOM will attempt to preserve these.
http://purl.obolibrary.org/obo/OBI_0000702	454 Genome Sequencer FLX	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	GS-FLX	is a DNA sequencer which was first manufactured by 454 Life Science Corporation in 2008 and enables pyrosequencing to be performed. It comprises both optics and fluidics subsystems, which are controlled by a computer subsystem. The fluidics subsystem ensures accurate reagent dispensing. It consists of a reagents cassette (which holds the reagent containers), a sipper manifold, pumps, valves, and debubblers. The fluidics subsystem flows the sequencing reagents across the wells of the PicoTiterPlate device, and moves the spent reagents from the PicoTiterPlate device to the waste receptacle. The optics subsystem consists of a CCD camera and a camera controller. The camera captures the light emitted in the wells of the PicoTiterPlate device during each step of the sequencing cycle, and sends the digital images to the computer subsystem for processing. The computer controls the other Sequencer subsystems, and processes the digital images sent by the camera to extract the DNA sequence information.  It has the ability to sequence 400-600 million base pairs per run with 400-500 base pair read lengths.
http://purl.obolibrary.org/obo/OBI_0000709	yeast artificial chromosome vector	http://purl.obolibrary.org/obo/CHEBI_4705	double-stranded DNA	YAC	a double-stranded DNA that was engineered to contain a yeast origin of replication, encodes for a selectable gene product, contains a cloning site, and has yeast telomerase sequences
http://purl.obolibrary.org/obo/OBI_0000711	library preparation	http://purl.obolibrary.org/obo/OBI_0000094	material processing	library construction	is a process which results in the creation of a library from fragments of DNA using cloning vectors or oligonucleotides with the role of adaptors.
http://purl.obolibrary.org/obo/OBI_0000716	ChIP-seq assay	http://purl.obolibrary.org/obo/OBI_0001954	ChIP assay	chromatin immunoprecipitation sequencing assay	An assay in which chromatin is immunoprecipitated and subsequently analyzed using a DNA sequencing step to identify which parts of DNA are part of the isolated chromatin
http://purl.obolibrary.org/obo/OBI_0000722	paired-end library	http://purl.obolibrary.org/obo/OBI_0000047	processed material	paired-end tag (PET) library	is a collection of short paired tags from the two ends of DNA fragments are extracted and covalently linked as ditag constructs
http://purl.obolibrary.org/obo/OBI_0000724	Solexa sequencing assay	http://purl.obolibrary.org/obo/OBI_0000734	DNA sequencing by synthesis assay	reversible terminator sequencing	A DNA sequencing by synthesis assay that identifies sequence information using DNA polymerase and reversible terminator, requiring immobilization of genomic DNA fragments onto a surface and a specific clonal amplification step known as bridge PCR. Reliance on a reversible terminator allows cycles of DNA chain extension by DNA polymerase and imaging without the need of electrophoretic separation of newly synthesized DNA fragment as with Sanger sequencing.
http://purl.obolibrary.org/obo/OBI_0000727	k-nearest neighbors	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation	k-NN	A k-nearest neighbors is a data transformation which achieves a class discovery or partitioning objective, in which an input data object with vector y is assigned to a class label based upon the k closest training data set points to y; where k is the largest value that class label is assigned.
http://purl.obolibrary.org/obo/OBI_0000736	single fragment library	http://purl.obolibrary.org/obo/OBI_0000047	processed material	fragment library	is a collection of short tags from DNA fragments, are extracted and covalently linked as single tag constructs
http://purl.obolibrary.org/obo/OBI_0000744	material sampling process	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process	sampling	A specimen gathering process with the objective to obtain a specimen that is representative of the input material entity
http://purl.obolibrary.org/obo/OBI_0000747	material sample	http://purl.obolibrary.org/obo/OBI_0100051	specimen	sample population	A material entity that has the material sample role
http://purl.obolibrary.org/obo/OBI_0000749	CART	http://purl.obolibrary.org/obo/OBI_0000707	decision tree building data transformation	classification and regression trees	A CART (classification and regression trees) is a data transformation method for producing a classification or regression model with a tree-based structure.
http://purl.obolibrary.org/obo/OBI_0000750	study design independent variable	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	independent variable	a directive information entity that is part of a study design. Independent variables are entities whose values are selected to determine its relationship to an observed phenomenon (the dependent variable). In such an experiment, an attempt is made to find evidence that the values of the independent variable determine the values of the dependent variable (that which is being measured). The independent variable can be changed as required, and its values do not represent a problem requiring explanation in an analysis, but are taken simply as given. The dependent variable on the other hand, usually cannot be directly controlled
http://purl.obolibrary.org/obo/OBI_0000751	study design dependent variable	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	dependent variable	dependent variable specification is part of a study design. The dependent variable is the event studied and expected to change when the independent variable varies.
http://purl.obolibrary.org/obo/OBI_0000785	study design controlled variable	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	controlled variable	Controlled variable specification  is a part of a study design. They are the entities that could vary, but are kept constant to prevent their influence on the effect of the independent variable on the dependent.
http://purl.obolibrary.org/obo/OBI_0000787	human antithrombin-III in blood assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	AT-III assay	An assay that measures the amount of antithrombin III in blood.
http://purl.obolibrary.org/obo/OBI_0000791	multiple testing correction objective	http://purl.obolibrary.org/obo/OBI_0200186	error correction objective	multiple comparison correction objective	A multiple testing correction objectives is a data transformation objective where the aim is to correct for a set of statistical inferences considered simultaneously
http://purl.obolibrary.org/obo/OBI_0000795	glucometer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device	glucose meter	A measurement device with the function to measure and record the level/amount of glucose in a blood sample
http://purl.obolibrary.org/obo/OBI_0000796	purification objective	http://purl.obolibrary.org/obo/OBI_0000681	separation into different composition objective	isolation objective	The objective to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest
http://purl.obolibrary.org/obo/OBI_0000801	spike train datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	spike train measurement	A measurement datum which represents information about an ordered series of action potentials in an organism's CNS measured over time.
http://purl.obolibrary.org/obo/OBI_0000805	antithrombin-III berichrome assay	http://purl.obolibrary.org/obo/OBI_0000787	human antithrombin-III in blood assay	AT-III assay	An antithrombin-III (AT-III) assay in which exogenous bovine thrombin and heparin are added to test plasma to form a thrombin-heparin-AT complex. The residual thrombin not bound then hydrolyzes the p-nitroalanine substrate to produce a yellow color, which is read at 405 nm. The intensity of color produced is inversely proportional to the AT present. A calibration is done with standard human plasma reagent and results for a given specimen are reported as a percentage relative to the standard
http://purl.obolibrary.org/obo/OBI_0000807	presentation of stimulus	http://purl.obolibrary.org/obo/OBI_0000011	planned process	stimulation of organism	A planned process with the objective to expose an organism to a stimulus.
http://purl.obolibrary.org/obo/OBI_0000816	micro electrode	http://purl.obolibrary.org/obo/OBI_0000832	measurement device	micro electrode measuring device	An electrode of very fine caliber consisting usually of a fine wire or a glass tube of capillary diameter drawn to a fine point and filled with saline or a metal used in physiological experiments to stimulate or record action currents of extracellular or intracellular origin in the nervous system.
http://purl.obolibrary.org/obo/OBI_0000820	activated partial thromboplastin time assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay	aPTT assay	An assay that evaluates blood coagulation by measuring the time required for the appearance of fibrin strands following the mixing blood or plasma with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of blood coaguation . It is used as a screening test and to monitor heparin therapy.
http://purl.obolibrary.org/obo/OBI_0000836	test tube	http://purl.obolibrary.org/obo/OBI_0000522	vial	sample tube	A test tube is a device consisting of a glass or plastic tubing, open at the top, usually with a rounded U-shaped bottom which has the function to contain material
http://purl.obolibrary.org/obo/OBI_0000860	northern blot assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	northern blot	An assay that determines the presence of gene transcripts by hybridizing labeled RNA or DNA probes against messenger RNAs isolated from tissue or cell cultures, resolved on denaturing gel, transfered by a blotting procedure to a solid support. Detection of hybridization signals is carried out by immunofluorescence or radioactivity measurements using photographic films or digital imaging devices such as Phosphor Imager.
http://purl.obolibrary.org/obo/OBI_0000865	96-well neutralization assay	http://purl.obolibrary.org/obo/OBI_0000872	serum neutralization of viral infectivity assay	microneutralization assay	A serum neutralization of viral infectivity assay which is performed in a 96-well plate.
http://purl.obolibrary.org/obo/OBI_0000871	viral hemagglutination assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	viral haemagglutinin assay	An assay that quantifies viruses by their hemagglutination activity.
http://purl.obolibrary.org/obo/OBI_0000872	serum neutralization of viral infectivity assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay	influenza neutralization assay	An analyte assay that measures virus-neutralizing abilities of different sera. Different dilutions of serum are mixed with virus and used to infect cells. At the lower dilutions, antibodies will block infection, but at higher dilutions, there will be too few antibodies to have an effect.The neutralization titer is expressed as the reciprocal of the highest dilution at which virus infection is blocked.
http://purl.obolibrary.org/obo/OBI_0000875	viral hemagglutination inhibition assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	viral haemagglutinin inhibition assay	An assay that measures the ability of an evaluant to inhibit hemagglutination by a virus. Hemagglutinin is a viral protein which binds to sialic acid receptors on cells or to erythrocytes, causing the cells to clump. Loss of clumping indicates that the evaluant blocks binding of hemagglutinin to sialic acid receptors.
http://purl.obolibrary.org/obo/OBI_0000877	cell line immortalization	http://purl.obolibrary.org/obo/OBI_0001867	establishing cell line	'establishing immortal cell line through directed genetic modification'	an establishing cell line process whereby a mortal cell line is intentionally genetically modified to be capable of indefinite propagation and re-established as a new immortal cell line
http://purl.obolibrary.org/obo/OBI_0000892	Southern blot assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	Southern blot	An analyte assay that detects the presence of a specific sequence in a DNA sample, which has been digested by restriction enzymes, resolved by gel electrophoresis, and blotted to a solid support, followed by hybridization of a probe raised against a specific sequence and detected with fluorescence or radioactivity.
http://purl.obolibrary.org/obo/OBI_0000893	real time polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	quantitative real time polymerase chain reaction	An assay, based on the PCR, that amplifies and simultaneously quantifies a specific DNA molecule based on the use of complementary probes/primers. It enables both detection and quantification (as absolute number of copies or relative amount when normalized to DNA input or additional normalizing genes) of one or more specific sequences in a DNA sample.
http://purl.obolibrary.org/obo/OBI_0000906	induced hemagglutination	http://purl.obolibrary.org/obo/OBI_0000094	material processing	hemeagglutination	The clumping or clustering of red blood cells caused by certain viruses, antibodies, or other substances
http://purl.obolibrary.org/obo/OBI_0000911	real time reverse-transcription polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	RT-rt PCR	An assay that uses a reverse transcription step (an RNA strand is reverse transcribed into its DNA complement using the enzyme reverse transcriptase) before a PCR assay.
http://purl.obolibrary.org/obo/OBI_0000916	flow cytometry assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay	FACS	A cytometry assay in which an input cell population is put in solution, is passed by a laser, and optical sensors are used to detect scattering of the laser light and/or fluorescence of specific markers to count and characterize the particles in solution.
http://purl.obolibrary.org/obo/OBI_0000918	Dulbecco's modified Eagle medium	http://purl.obolibrary.org/obo/OBI_0000079	culture medium	D-MEM	A culture medium containing iron, phenol red, amino acids, salts, glucose and vitamins.
http://purl.obolibrary.org/obo/OBI_0000919	animal euthanization	http://purl.obolibrary.org/obo/OBI_0600006	killing	animal sacrifice	A process in which is the end of life of animal is brought about in accordance with local regulations on treatment of animal subjects and using a method which causes minimal pain and distress to the animal subject
http://purl.obolibrary.org/obo/OBI_0000920	cytometric bead array assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	Luminex assay	An analyte assay in which a series of beads coated with antibodies, antigens, or other small molecules are used to detect an analyte of interest.
http://purl.obolibrary.org/obo/OBI_0000930	calorimeter	http://purl.obolibrary.org/obo/OBI_0000832	measurement device	calorimetry instrument?	A measurement device that is used to calculate the heat flow of a chemical reaction or physical change.
http://purl.obolibrary.org/obo/OBI_0000933	positron emission tomography scanner	http://purl.obolibrary.org/obo/OBI_0000398	image creation device	PET scanner?	A device that produces a three-dimensional image or picture of functional processes in the body. It detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on a biologically active molecule.
http://purl.obolibrary.org/obo/OBI_0000938	categorical measurement datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	nominal mesurement datum	A measurement datum that is reported on a categorical scale.
http://purl.obolibrary.org/obo/OBI_0000944	handedness assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	handedness test	An assay that measures the unequal distribution of fine motor skill between the left and right hands typically in human subjects by means of some questionnaire and scoring procedure.
http://purl.obolibrary.org/obo/OBI_0000966	in live organism assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	in vivo assay	An assay in which a measurement is made by observing entities located in an organism.
http://purl.obolibrary.org/obo/OBI_0000968	device	http://purl.obolibrary.org/obo/OBI_0000047	processed material	instrument	A material entity that is designed to perform a function in a scientific investigation, but is not a reagent.
http://purl.obolibrary.org/obo/OBI_0000970	scalar score from composite inputs	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	questionaire score	A measurement datum which is the result of combining multiple datum. For example, a mean or summary score.
http://purl.obolibrary.org/obo/OBI_0000982	computed tomography scanner	http://purl.obolibrary.org/obo/OBI_0000398	image creation device	X-ray computed tomography scanner	An image acquisition device that generates a three-dimensional image of the inside of an object from a large series of two-dimensional X-ray images taken around a single axis of rotation.
http://purl.obolibrary.org/obo/OBI_0001002	Faraday cage	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device	Faraday shield	A device formed by conducting material or by a mesh of such material, that blocks out external static electric fields.
http://purl.obolibrary.org/obo/OBI_0001005	RNASE CL3 structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using RNAse CL3	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse CL3 as reagent and enzymatic probe.
http://purl.obolibrary.org/obo/OBI_0001006	CMCT structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using CMCT probe	A single-nucleotide-resolution nucleic acid structure mapping assay which uses CMCT as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure
http://purl.obolibrary.org/obo/OBI_0001007	image creation	http://purl.obolibrary.org/obo/OBI_0000011	planned process	image acquisition	A planned process that captures an image of an object.
http://purl.obolibrary.org/obo/OBI_0001008	MPE-Fe(II) structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using Fe-MP probe	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at the nucleotide resolution scale using Fe-MP as reagent and chemical probe.
http://purl.obolibrary.org/obo/OBI_0001011	ENU structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using ENU probe	A single-nucleotide-resolution nucleic acid structure mapping assay that determines the secondary structure of a nucleic acid at the nucleotide resolution scale which uses ENU as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001012	RNASE V1 structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using RNAse V1	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse V1 as reagent and enzymatic probe
http://purl.obolibrary.org/obo/OBI_0001015	DMS structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using DMS probe	A single-nucleotide-resolution nucleic acid structure mapping assay which determins nucleic acid secondary structure at a nucleotide resolution scale using DMS as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001016	DNASE 1 structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using DNAse I	A single-nucleotide-resolution deoxyribonucleic acid structure mapping assay which uses DNAse 1 as reagent and enzymatic probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure
http://purl.obolibrary.org/obo/OBI_0001018	Rhodium DNA structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using Rhodium probe	A single-nucleotide-resolution nucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using Rhodium as reagent and chemical probe.
http://purl.obolibrary.org/obo/OBI_0001019	RNA ADA I RNA structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using RNA adenosine deaminase I	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNA adenosine deaminase I as reagent and enzymatic probe.
http://purl.obolibrary.org/obo/OBI_0001020	Lead structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using Lead probe	A single-nucleotide-resolution nucleic acid structure mapping assay that determines nucleic acid secondary structure at nucleotide resolution scale using lead as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001021	RNASE T2 structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using RNAse T2	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse T2 as reagent and enzymatic probe
http://purl.obolibrary.org/obo/OBI_0001023	Fe-BABE RNA structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using Fe-BABE probe	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic secondary structure at a nucleotide resolution scale using Fe-BABE as reagent and chemical probe.
http://purl.obolibrary.org/obo/OBI_0001024	RNASE U2 structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using RNAse U2	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAase U2 as reagent and enzymatic probe
http://purl.obolibrary.org/obo/OBI_0001026	NMIA RNA structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using NMIA probe	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at the nucleotide resolution scale using NMIA as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001027	Terbium RNA structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using Terbium probe	A single-nucleotide-resolution nucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using Terbium as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001029	OH-radical structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	single nucleotide resolution mapping assay using OH-radical probe	A single-nucleotide-resolution nucleic acid structure mapping assay hat determines nucleic acid secondary structure at a nucleotide resolution scale using hydroxyl radical as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001030	RNASE T1 structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using RNAse T1	A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale uses RNAse T1 as reagent and enzymatic probe.
http://purl.obolibrary.org/obo/OBI_0001031	array image creation	http://purl.obolibrary.org/obo/OBI_0001007	image creation	array image acquisition	An image creation process that generate an image from the array.
http://purl.obolibrary.org/obo/OBI_0001035	Nuclease S1 structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	single nucleotide resolution mapping assay using Nuclease S1	A single-nucleotide-resolution deoxyribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using DNAse 1 as reagent and enzymatic probe.
http://purl.obolibrary.org/obo/OBI_0001041	stabilization function	http://purl.obolibrary.org/obo/BFO_0000034	function	isolation function	A stabilization function is a function that holds or isolates an entity such as an instrument or specimen steadfast or at an unfluctuating level or quantity.
http://purl.obolibrary.org/obo/OBI_0001138	X-ray source	http://purl.obolibrary.org/obo/OBI_0000968	device	x-ray generator	A device that is used to generate X-rays.
http://purl.obolibrary.org/obo/OBI_0001143	labeled nucleic acid extract	http://purl.obolibrary.org/obo/OBI_0000924	labeled specimen	labeled extract	a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments.
http://purl.obolibrary.org/obo/OBI_0001158	age determination assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	age measurement assay	An assay that determines the duration of part of the life of an organism, where the initial time point is the beginning of some transitional state (such as birth or when planted).
http://purl.obolibrary.org/obo/OBI_0001171	half life datum (t 1/2)	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum	t 1/2	The time it takes for 50% of a class of stochastic processes to occur.
http://purl.obolibrary.org/obo/OBI_0001174	passive immunization	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo	adoptive transfer	The injection of immune effector material (antibodies, T cells or B cells) into an organism so that the organisms immune system gains its  immune effector function to recognize specific antigens.
http://purl.obolibrary.org/obo/OBI_0001178	efficacy of epitope intervention experiment	http://purl.obolibrary.org/obo/OBI_0000070	assay	efficacy of in vivo intervention	An assay that tests  if inducing an epitope specific immune response in an organism has an effect, such as the ability to prevent, treat or exacerbate diseases in the organism.
http://purl.obolibrary.org/obo/OBI_0001179	epitope protection from infectious challenge experiment	http://purl.obolibrary.org/obo/OBI_0001184	epitope protection experiment	protection from infectious challenge	An epitope protection experiment in which the ability of the epitope to protect the host from an infection is assessed.
http://purl.obolibrary.org/obo/OBI_0001183	epitope protection from tumor challenge experiment	http://purl.obolibrary.org/obo/OBI_0001184	epitope protection experiment	protection from tumor challenge	An epitope protection experiment in which the ability of the epitope to protect the host from developing tumors is assessed.
http://purl.obolibrary.org/obo/OBI_0001184	epitope protection experiment	http://purl.obolibrary.org/obo/OBI_0001178	efficacy of epitope intervention experiment	protection from challenge	An efficacy of epitope intervention experiment that tests the efficacy of inducing an immune epitope response to prevent disease in a host.
http://purl.obolibrary.org/obo/OBI_0001185	selectively maintained organism	http://purl.obolibrary.org/obo/OBI_0100026	organism	ecotype	An organism that is bred to have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms
http://purl.obolibrary.org/obo/OBI_0001186	epitope protection from infectious challenge experiment based on pathogen burden	http://purl.obolibrary.org/obo/OBI_0001179	epitope protection from infectious challenge experiment	burden after infectious challenge	An epitope protection from infectious challenge experiment in which the readout is a reduction in the presence of pathogens in the host compared to controls.
http://purl.obolibrary.org/obo/OBI_0001188	epitope disease exacerbation experiment	http://purl.obolibrary.org/obo/OBI_0001178	efficacy of epitope intervention experiment	exacerbation assay	An efficacy of epitope intervention experiment that tests the ability of inducing an epitope immune response to increase the severity of an existing disease in the host.
http://purl.obolibrary.org/obo/OBI_0001189	epitope protection experiment based on survival	http://purl.obolibrary.org/obo/OBI_0001184	epitope protection experiment	host survival after challenge	An epitope protection experiment that determines the success of the epitope intervention based on increased survival of the host.
http://purl.obolibrary.org/obo/OBI_0001190	epitope treatment experiment	http://purl.obolibrary.org/obo/OBI_0001178	efficacy of epitope intervention experiment	decreased disease symptoms after treatment	An epitope intervention experiment that tests the ability of inducing an epitope immune response to treat an existing disease  in the host.
http://purl.obolibrary.org/obo/OBI_0001248	ChIP-chip assay	http://purl.obolibrary.org/obo/OBI_0001954	ChIP assay	ChIP-on-chip assay	An assay in which chromatin is immunoprecipitated and subsequently analyzed using a DNA microarray to identify which parts of DNA are part of the isolated chromatin
http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	http://purl.obolibrary.org/obo/OBI_0001177	RNA sequencing assay	transcription profiling by high throughput sequencing	An RNA sequencing assay that determines an RNA sequence by analyzing the transcibed regions of the genome and or to quantitate transcript abundance.
http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	genome tiling array	A DNA microarray which has short fragments of nucleic acid immobilized on a substrate. These are designed to cover the whole genome of the target species. Tiling arrays are used to determine genome binding in ChIP assays or to identify transcribed regions.
http://purl.obolibrary.org/obo/OBI_0001393	comparative genomic hybridization by array assay	http://purl.obolibrary.org/obo/OBI_0001985	microarray assay	array CGH	An assay that measures changes in DNA sequence copy number using a microarray. For example the analysis of LOH in tumor cells vs a non diseased sample or the comparison of clinical isolated of disease causing bacteria.
http://purl.obolibrary.org/obo/OBI_0001403	ChIP-chip design	http://purl.obolibrary.org/obo/OBI_0001425	protein binding site identification design	ChIP-on-chip design	A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and DNA microarray (chip) assays.
http://purl.obolibrary.org/obo/OBI_0001442	q-value	http://purl.obolibrary.org/obo/OBI_0000071	quantitative confidence value	FDR adjusted p-value	A quantitative confidence value that measures the minimum false discovery rate that is incurred when calling that test significant. 
To compute q-values, it is necessary to know the p-value produced by a test and possibly set a false discovery rate level.
http://purl.obolibrary.org/obo/OBI_0001463	transcription profiling by array assay	http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay	RNA profiling by array assay	A transcription profiling assay that uses array technology.
http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism	http://purl.obolibrary.org/obo/OBI_0100051	specimen	tissue specimen	A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm).
http://purl.obolibrary.org/obo/OBI_0001486	disposition to be bound by an MHC protein complex	http://purl.obolibrary.org/obo/BFO_0000016	disposition	MHC ligand disposition	Is the disposition borne by a material entity that is realized in a process of being bound in the antigen binding grove of an MHC protein complex.
http://purl.obolibrary.org/obo/OBI_0001488	epitope tolerance induction experiment	http://purl.obolibrary.org/obo/OBI_0001178	efficacy of epitope intervention experiment	tolerance induction	An efficacy of epitope intervention experiment that tests the ability of the intervention to decrease an existing immune response
http://purl.obolibrary.org/obo/OBI_0001508	sampling time measurement datum	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum	time point	A time measurement datum when an observation is made or a sample is taken from a material as measured from some reference point.
http://purl.obolibrary.org/obo/OBI_0001566	50% dissociation of binding temperature (Tm)	http://purl.obolibrary.org/obo/OBI_0003142	quantitative binding datum	melting temperature (Tm)	A quantitative binding datum that specifies the temperature at which half of the binding partners are forming a complex and the other half are unbound.
http://purl.obolibrary.org/obo/OBI_0001616	specimen identifier	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol	specimen ID	A CRID symbol denotes a specimen and used to distinguish one specimen from another in an investigation.
http://purl.obolibrary.org/obo/OBI_0001617	PubMed ID	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol	PubMed Identifier	A CRID symbol that is sufficient to look up a citation from the PubMed, a literature database of life sciences and biomedical information.
http://purl.obolibrary.org/obo/OBI_0001619	specimen collection time measurement datum	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum	collection date	A time measurement datum that is the measure of the time when the specimens are collected.
http://purl.obolibrary.org/obo/OBI_0001620	latitude coordinate measurement datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	latitude	A measurement datum that is the measure of the latitude coordinate of a site.
http://purl.obolibrary.org/obo/OBI_0001621	longitude coordinate measurement datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	longitude	A measurement datum that is the measure of the longitude coordinate of a site.
http://purl.obolibrary.org/obo/OBI_0001624	organism species detection assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	organism identification assay	An organism detection assay that identifies the organism species in a specimen.
http://purl.obolibrary.org/obo/OBI_0001626	Bioinformatics Resource Center	http://purl.obolibrary.org/obo/OBI_0000245	organization	BRC	An organization that  is one of the Internet-based research centers established and funded by NIAID (the National Institute of Allergy and Infectious Diseases). The Bioinformatics Resource Centers (BRCs) were formed in response to the threats posed by emerging and re-emerging pathogens, particularly CDC Category A, B, and C pathogens, and their potential use in bioterrorism. The intention of NIAID in funding these bioinformatics centers is to assist researchers involved in the experimental characterization of such pathogens and the formation of drugs, vaccines, or diagnostic tools to combat them.
http://purl.obolibrary.org/obo/OBI_0001670	RNA protection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	RNAse protection assay	An assay that determines the presence and estimates abundance of transcript species by first creating an homo or heteroduplex by adding a specific, complementary sequence to the sequence of interest and then exposing the mixture of ribonuclease, which will degrade only single stranded molecules. A detection step will reveal if the sample contained a sequence of interest.
http://purl.obolibrary.org/obo/OBI_0001671	electrophoretic mobility shift assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay	gel shift assay	An assay that measures information about Protein-DNA or Protein-RNA interactions using gel electrophoresis and relying on the fact the molecular interactions will cause the heterodimer to be retarded on the gel when compared to controls corresponding to protein extract alone and protein extract + neutral nucleic acid.
http://purl.obolibrary.org/obo/OBI_0001673	nano-cap analysis of gene expression assay	http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay	nano-CAGE	A transcription profiling assay that is performed using a very low amount (nanogram scale) of mRNA samples using Cap analysis gene expression (CAGE).
http://purl.obolibrary.org/obo/OBI_0001674	cap analysis of gene expression assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	CAGE	A transcription profiling assay which measures RNA transcript abundances in biological samples by extracting 5' ends of capped transcripts, RTPCR and sequence those. Copy numbers of CAGE tags provide a way of quantification and provide a measure of expression of the transcriptome
http://purl.obolibrary.org/obo/OBI_0001679	yeast 2-hybrid assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay	Y2H	An assay that detects protein protein interactions and protein DNA interactions by testing for physical interactions (such as binding) between two proteins or a single protein and a DNA molecule, respectively. The premise behind the test is the activation of downstream reporter gene(s) by the binding of a transcription factor onto an upstream activating sequence (UAS). For two-hybrid screening, the transcription factor is split into two separate fragments, called the binding domain (BD) and activating domain (AD). The BD is the domain responsible for binding to the UAS and the AD is the domain responsible for the activation of transcription. The Y2H is thus a protein-fragment complementation assay.
http://purl.obolibrary.org/obo/OBI_0001680	Sos-recruitment assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay	SRS	A binding assay that detects interacting proteins for a targeted domain where mammalian guanyl nucleotide exchange factor (GEF) Sos is recruited to the Saccharomyces cerevisiae plasma membrane harboring a temperature-sensitive Ras GEF, Cdc25-2, allowing growth at the nonpermissive temperature using the Sos recruitment system, a kind of yeast 2 hybrid system.
http://purl.obolibrary.org/obo/OBI_0001681	yeast one-hybrid assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay	Y1H	An assay that determines protein DNA interactions using a single fusion protein in which the activating domain is linked directly to the binding domain.
http://purl.obolibrary.org/obo/OBI_0001682	bacterial one-hybrid assay	http://purl.obolibrary.org/obo/OBI_0001681	yeast one-hybrid assay	B1H	An assay that identifies the sequence-specific target site of a DNA-binding domain. In this system, a given transcription factor (TF) is expressed as a fusion to a subunit of RNA polymerase. In parallel, a library of randomized oligonucleotides representing potential TF target sequences, is cloned into a separate vector containing the selectable genes HIS3 and URA3. If the DNA-binding domain (bait) binds a potential DNA target site (prey) in vivo, it will recruit RNA polymerase to the promoter and activate transcription of the reporter genes in that clone. The two reporter genes, HIS3 and URA3, allow for positive and negative selections, respectively. At the end of the process, positive clones are sequenced and examined with motif-finding tools in order to resolve the favoured DNA target sequence
http://purl.obolibrary.org/obo/OBI_0001684	methylation-specific polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	MSP	An assay that uses initial modification of DNA by sodium bisulfite, converting all unmethylated, but not methylated, cytosines to uracil, and subsequent amplification with primers specific for methylated versus unmethylated DNA.
http://purl.obolibrary.org/obo/OBI_0001685	amplification of intermethylated sites assay	http://purl.obolibrary.org/obo/OBI_0000634	DNA methylation profiling assay	intermethylated site amplification	An assay that estimates genome-wide DNA methylation and measures methylation of DNA sequences. AIMS is based on the differential enzymatic digestion of genomic DNA with methylation-sensitive and methylation-insensitive isoschizomers followed by restrained PCR amplification of methylated sequences.
http://purl.obolibrary.org/obo/OBI_0001686	in-situ hybridization assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	in situ hybridization	An assay that localizes a specific DNA or RNA sequence within a portion or section of tissue using artificially induced nucleic hybridization.
http://purl.obolibrary.org/obo/OBI_0001699	antibody cross-blocking assay	http://purl.obolibrary.org/obo/OBI_0001593	competitive inhibition of binding assay	antibody inhibition of antibody binding	A competitive inhibition of binding assay in which two antibodies that are known to bind the same antigen are tested for the ability of one antibody to inhibit binding of the other antibody to the antigen, thereby determining if they have overlapping binding sites.
http://purl.obolibrary.org/obo/OBI_0001755	selection criterion	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	selection rule	A directive information entity which defines and states a principle of standard by which selection process may take place.
http://purl.obolibrary.org/obo/OBI_0001848	chromatin interaction analysis by paired-end tag sequencing assay	http://purl.obolibrary.org/obo/OBI_0002438	nuclear ligation assay	ChIA-PET assay	An assay that incorporates chromatin immunoprecipitation (ChIP)-based enrichment, chromatin proximity ligation, Paired-End Tags, and high-throughput sequencing to determine de novo long-range chromatin interactions genome-wide.
http://purl.obolibrary.org/obo/OBI_0001849	structural analysis by paired-end tag sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	DNA-PET assay	An assay that incorporates Paired-End Tags and sequencing technology to determine structural variants.
http://purl.obolibrary.org/obo/OBI_0001850	transcript analysis by paired-end tag sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	RNA-PET assay	A transcription profiling assay that determines transcripts, gene structures, and gene expressions using Paired-End Tags and sequencing technology.
http://purl.obolibrary.org/obo/OBI_0001857	RNP (ribonuclear particle) immunoprecipitation high- throughput sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	RIP-seq assay	An analyte assay that combines immunoprecipitation of an RNA-binding protein and RNA-seq to identify mRNAs associated with selected RNA binding proteins (RBPs).
http://purl.obolibrary.org/obo/OBI_0001858	cross-linking immunoprecipitation high-throughput sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	HITS-CLIP	An analyte assay that employs UV-crosslinking between RNA and a protein, followed by immunoprecipitation with antibodies for the protein, fragmentation, and high-throughput screening for RNA sequences that interact with a particular RNA-binding protein.
http://purl.obolibrary.org/obo/OBI_0001859	formaldehyde-assisted isolation of regulatory elements assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	FAIRE-seq assay	An assay to determine the sequences of those DNA regions in the genome associated with regulatory activity.
http://purl.obolibrary.org/obo/OBI_0001861	methylation-sensitive restriction enzyme sequencing assay	http://purl.obolibrary.org/obo/OBI_0001266	DNA methylation profiling by high throughput sequencing assay	MRE-seq assay	An assay that identifies unmethylated CpGs using methylation sensitive restriction enzymes to fragment DNA.
http://purl.obolibrary.org/obo/OBI_0001862	reduced representation bisulfite sequencing assay	http://purl.obolibrary.org/obo/OBI_0000748	bisulfite sequencing assay	reduced representation bisulfite-seq	A bisulfite sequencing assay that identifies genomic methylation patterns using a bisulfite based protocol that enriches CG-rich parts of the genome.
http://purl.obolibrary.org/obo/OBI_0001863	shotgun bisulfite-seq assay	http://purl.obolibrary.org/obo/OBI_0000748	bisulfite sequencing assay	whole-genome shotgun bisulfite sequencing	A bisulfite sequencing assay that identifies methylated cytosines across the genome using high throughput sequencing.
http://purl.obolibrary.org/obo/OBI_0001864	RNA Annotation and Mapping of Promoters for the Analysis of Gene Expression assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	RAMPAGE	An transcription profiling assay that identifies transcription start sites (TSS), the quantification of their expression and the characterization of their transcripts using high throughput sequencing.
http://purl.obolibrary.org/obo/OBI_0001868	genetic material	http://purl.obolibrary.org/obo/CHEBI_33696	nucleic acid	hereditary genetic material	A nucleic acid macromolecule that is part of a cell or virion and is inherited from an immediate ancestor, or incorporated in a manner that it has the disposition to be replicated and inherited by descendants.
http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	http://purl.obolibrary.org/obo/OBI_0100060	cultured cell population	immune cell culture sample	a cultured cell population comprised of a single type of immune system cell
http://purl.obolibrary.org/obo/OBI_0001877	random access memory	http://purl.obolibrary.org/obo/IAO_0000178	material information bearer	RAM	Random-access memory (RAM) is a form of computer data storage. A random-access device allows stored data to be accessed directly in any random order. In contrast, other data storage media such as hard disks, CDs, DVDs and magnetic tape, as well as early primary memory types such as drum memory, read and write data only in a predetermined order, consecutively, because of mechanical design limitations. Therefore, the time to access a given data location varies significantly depending on its physical location
http://purl.obolibrary.org/obo/OBI_0001905	secondary cultured cell population	http://purl.obolibrary.org/obo/OBI_0100060	cultured cell population	secondary cell culture sample	A cultured cell population that is derived through one or more passages in culture.
http://purl.obolibrary.org/obo/OBI_0001908	testable hypothesis	http://purl.obolibrary.org/obo/IAO_0000030	information content entity	hypothesis	An information content entity that expresses an assertion that is intended to be tested.
http://purl.obolibrary.org/obo/OBI_0001913	computation run time	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum	computation run time datum	computation run time is a time measurement datum which corresponds the time expressed in second, minute, hour necessary for a computer program to complete a process execution, for example genome assembly. It is an important metrics as it indicates the resource occupancy and computer program efficiency.
http://purl.obolibrary.org/obo/OBI_0001914	multiplex ligation-mediated amplification	http://purl.obolibrary.org/obo/OBI_0000415	polymerase chain reaction	Multiplex ligation-dependent probe amplification	A polymerase chain reaction that amplifies multiple targets with a single primer pair mediated by hybridization of a primer with its target sequence using ligation.
http://purl.obolibrary.org/obo/OBI_0001915	DNA replication timing by array assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	Repli-chip assay	An assay which quantifies the timing of DNA replication as a function of genome position using array technology.
http://purl.obolibrary.org/obo/OBI_0001918	RNA-binding protein immunoprecipitation array profiling assay	http://purl.obolibrary.org/obo/OBI_0001985	microarray assay	RIP-chip assay	An assay that combines immunoprecipitation of an RNA-binding protein and array technology to identify mRNAs associated with selected RNA binding proteins (RBPs).
http://purl.obolibrary.org/obo/OBI_0001919	Carbon-copy chromosome conformation capture assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	5C assay	An assay that measures the organization of chromosomes at the genome-wide scale.
http://purl.obolibrary.org/obo/OBI_0001920	DNA replication timing by sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	Repli-seq assay	An assay in which timing of DNA replication is quantified as a function of genome position based on genome-wide sequencing.
http://purl.obolibrary.org/obo/OBI_0001922	microRNA profiling by high throughput sequencing assay	http://purl.obolibrary.org/obo/OBI_0001926	microRNA profiling assay	miRNA-HTS	A microRNA profiling assay that analyzes the microRNA component of the transcriptome using high throughput sequencing technology.
http://purl.obolibrary.org/obo/OBI_0001924	micrococcal nuclease digestion followed by high throughput sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	MNase-seq assay	An assay that identifies nucleosome positioning by genome wide sequencing of regions sensitive to digestion by micrococal nuclease
http://purl.obolibrary.org/obo/OBI_0001925	chromatin immunoprecipitation with exonuclease sequencing assay	http://purl.obolibrary.org/obo/OBI_0000716	ChIP-seq assay	ChIP-exo assay	A ChIP-seq assay which uses immunoprecipitation to isolate protein bound DNA followed by an exonuclease step to degrade DNA that is not protein bound to provide greater resolution of the DNA binding site
http://purl.obolibrary.org/obo/OBI_0001926	microRNA profiling assay	http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay	microRNA expression assay	A transcription profiling assay that quantifies the microRNA species within a biological sample.
http://purl.obolibrary.org/obo/OBI_0001928	selection	http://purl.obolibrary.org/obo/OBI_0000011	planned process	selection process	A planned process with the objective to create a group of entities by applying a predefined criteria to a larger group of entities.
http://purl.obolibrary.org/obo/OBI_0001940	N50	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum	weighted median item size	the weighted median item size or N50 is a weighted median of the lengths of items, equal to the length of the longest item i such that the sum of the lengths of items greater than or equal in length to i is greater than or equal to half the length of all of the items. With regard to assemblies the items are typically contigs or scaffolds. It therefore denotes the ability of the software to create contigs and provides information about the resulting sequence assembly
http://purl.obolibrary.org/obo/OBI_0001942	grant agency	http://purl.obolibrary.org/obo/OBI_0000245	organization	funding organization	An organization that provides funding support for projects such as investigations.
http://purl.obolibrary.org/obo/OBI_0001946	forward PCR primer	http://purl.obolibrary.org/obo/CHEBI_16991	deoxyribonucleic acid	sense primer	A short oligonucleotide complementary to target DNA (5'->3' on plus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.
http://purl.obolibrary.org/obo/OBI_0001951	reverse PCR primer	http://purl.obolibrary.org/obo/CHEBI_16991	deoxyribonucleic acid	reverse primer	A short oligonucleotide complementary to target DNA (5'->3' on minus strand) that acts as the leader for DNA extension in a PCR reaction. The polymerase starts replication at the 3'-end of the primer, and copies the opposite strand. A primer is characterized by its 'melting temperature' (Tm) and pairs of primers should have similar Tm.
http://purl.obolibrary.org/obo/OBI_0001954	ChIP assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	chromatin immunoprecipitation assay	An assay in which portions of chromatin, the ordered and organized complex of DNA and its interaction partners that make up a chormosome, is extracted and purified by immunoprecipitation with antibodies or tags, and subsequently analyzed
http://purl.obolibrary.org/obo/OBI_0001960	taxonomic diversity assessment by targeted gene survey	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	targeted gene survey DNA barcoding	An assay that dteremines taxonomic and community diversity information by sequencing specific genomic regions used as marker of identity or diversity.
http://purl.obolibrary.org/obo/OBI_0001964	decision-theoretic analysis objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification	decision analysis objective	An objective specification which what includes a description of two or more alternative actions to take in a particular situation and a metric that enables comparisons of the two actions. The objective specified is achieved in a planned process which includes a data transformation, the output of which is an identification of the 'best' choice according to the metric.
http://purl.obolibrary.org/obo/OBI_0001971	Ion 316 Chip v2	http://purl.obolibrary.org/obo/OBI_0001973	ion semiconductor chip	Ion PGM 316 Chip v2	An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 316 chip is compatible with the Ion Torrent PGM and has a run time of: 3.0 hours for 200 bp reads with an output of 30-50 Mb, 4.9 hours for 400 bp reads with an output of 60 Mb-1 Gb.
http://purl.obolibrary.org/obo/OBI_0001972	Ion 318 Chip v2	http://purl.obolibrary.org/obo/OBI_0001973	ion semiconductor chip	Ion PGM 318 Chip v2	An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 318 chip is compatible with the Ion Torrent PGM and has a run time of: 4.4 hours for 200 bp reads with an output of 60 Mb-1 Gb, 7.3 hours for 400 bp reads with an output of 1.2 Gb-2 Gb.
http://purl.obolibrary.org/obo/OBI_0001973	ion semiconductor chip	http://purl.obolibrary.org/obo/OBI_0000364	ion detector	ion semiconductor	An ion detector that is organized as an electronic circuit whose components, such as transistors and resistors, are etched or deposited on a single slice of semiconductor material to produce a chip. The specific chip detects ion charge induced when an ion passes by or hits a surface.
http://purl.obolibrary.org/obo/OBI_0001974	Ion 314 Chip v2	http://purl.obolibrary.org/obo/OBI_0001973	ion semiconductor chip	Ion PGM 314 Chip v2	An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 314 chip is compatible with the Ion Torrent PGM and has a run time of: 2.3 hours for 200 bp reads with an output of 30-50 Mb, 3.7 hours for 400 bp reads with an output of 60-100 Mb.
http://purl.obolibrary.org/obo/OBI_0002000	Illumina Genome Analyzer IIx	http://purl.obolibrary.org/obo/OBI_0000703	Illumina Genome Analyzer II	Illumina GA IIx	An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIx is the most widely adopted next-generation sequencing platform and proven and published across the broadest range of research applications.
http://purl.obolibrary.org/obo/OBI_0002001	Illumina HiSeq 2000	http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	HiSeq 2000	A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and a throughput of up to 55 Gb per day. Built upon sequencing by synthesis technology, the machine is optimized for generation of data for multiple samples in a single run.
http://purl.obolibrary.org/obo/OBI_0002002	Illumina HiSeq 2500	http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	HiSeq 2500	A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and a throughput of up to 160 Gb per day. Built upon sequencing by synthesis technology, the machine is optimized for generation of data for batching multiple samples or rapid results on a few samples.
http://purl.obolibrary.org/obo/OBI_0002003	Illumina MiSeq	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	MiSeq	A DNA sequencer which is manufactured by the Illumina corporation. Built upon sequencing by synthesis technology, the machine provides an end-to-end solution (cluster generation, amplification, sequencing, and data analysis) in a single machine.
http://purl.obolibrary.org/obo/OBI_0002004	Methylation 450K BeadChip	http://purl.obolibrary.org/obo/OBI_0001870	Illumina methylation BeadChip	Illumina Infinium Human Methylation 450K BeadChip	A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 485,000 methylation sites per sample at single-nucleotide resolution.
http://purl.obolibrary.org/obo/OBI_0002005	Methylation 27K BeadChip	http://purl.obolibrary.org/obo/OBI_0001870	Illumina methylation BeadChip	Illumina Infinium Human Methylation 27K BeadChip	A methylation BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array interrogates ~ 27,000 CpG sites per sample at single-nucleotide resolution.
http://purl.obolibrary.org/obo/OBI_0002006	1M-Duo Infinium HD BeadChip	http://purl.obolibrary.org/obo/OBI_0001869	Illumina BeadChip	Illumina Human 1M-Duo Infinium HD BeadChip	A BeadChip which is manufactured by the Illumina corporation. Built upon BeadChip tehcnology, the array integrates ~ 1 million markers per sample for genotyping, and copy number variation (CNV) and Cytogenetic analysis.
http://purl.obolibrary.org/obo/OBI_0002007	SOLiD 3 Plus System	http://purl.obolibrary.org/obo/OBI_0000696	AB SOLiD System	Applied Biosystems SOLiD 3 Plus System	A DNA sequencer which is manufacted by the Applied Biosystems corporation. Built upon SOLiD sequencing technology, the machine generates greater than 1 billion mappable reads per run.
http://purl.obolibrary.org/obo/OBI_0002008	Mouse 385K Whole Genome CGH Tiling Array	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	Nimblegen Mouse 385K Whole Genome CGH Tiling Array	A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 385,000 features.
http://purl.obolibrary.org/obo/OBI_0002009	Mouse 3x720K Whole Genome CGH Tiling Array	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	Nimblegen Mouse 3x720K Whole Genome CGH Tiling Array	A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for mouse DNA against 3x720,000 features.
http://purl.obolibrary.org/obo/OBI_0002010	Human 3x720K Whole Genome CGH Tiling Array	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	Nimblegen Human 3x720K Whole Genome CGH Tiling Array	A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 3x720,000 features.
http://purl.obolibrary.org/obo/OBI_0002011	Human 2.1M Whole-Genome CGH Tiling Array v2.0	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	Nimblegen Human 2.1M Whole-Genome CGH Tiling Array v2.0	A tiling array which is manufactured by the Nimblegen corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 2.1 million features.
http://purl.obolibrary.org/obo/OBI_0002012	PacBio RS II	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	Pacific Biosciences RS II	A DNA sequencer which is manufactured by the Pacific Biosciences corporation. Built upon single molecule real-time sequencing technology, the machine is optimized for generation with long reads and high consensus accuracy.
http://purl.obolibrary.org/obo/OBI_0002014	DNA methylation profiling by ChIP-chip assay	http://purl.obolibrary.org/obo/OBI_0002020	epigenetic modification assay	DNA methylation ChIP-chip	An epigenetic modification assay that identifies sites of DNA methylation using ChIP-chip technologies.
http://purl.obolibrary.org/obo/OBI_0002015	transcription profiling by MPSS assay	http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay	expression MPSS	A transcription profiling assay that uses Massive Parallel Signature Sequencing (MPSS).
http://purl.obolibrary.org/obo/OBI_0002016	histone modification identification by ChIP-chip assay	http://purl.obolibrary.org/obo/OBI_0002020	epigenetic modification assay	histone modification ChIP-chip	An epigenetic modification assay that identifies regions containing specific histones and their modifications using ChIP-chip techniques.
http://purl.obolibrary.org/obo/OBI_0002017	histone modification identification by ChIP-Seq assay	http://purl.obolibrary.org/obo/OBI_0002020	epigenetic modification assay	histone modification ChIP-Seq	An epigenetic modification assay that identifies regions containing specific histones and their modifications using ChIP-Seq techniques.
http://purl.obolibrary.org/obo/OBI_0002018	transcription factor binding site identification by ChIP-chip assay	http://purl.obolibrary.org/obo/OBI_0001248	ChIP-chip assay	TF Binding ChIP-chip	A transcription factor binding site assay that utilizes ChIP-chip technology.
http://purl.obolibrary.org/obo/OBI_0002019	transcription factor binding site identification by ChIP-Seq assay	http://purl.obolibrary.org/obo/OBI_0000716	ChIP-seq assay	TF Binding ChIP-Seq	A transcription factor binding site assay that utilizes ChIP-seq technology.
http://purl.obolibrary.org/obo/OBI_0002021	Illumina NextSeq 500	http://purl.obolibrary.org/obo/OBI_0003684	Illumina NextSeq series instrument	NextSeq 500	A DNA sequencer which is a desktop sequencer ideal for smaller-scale studies manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology.
http://purl.obolibrary.org/obo/OBI_0002022	Illumina HiSeq 1000	http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	HiSeq 1000	A DNA sequencer which is manufactured by the Illumina corporation, with a single flow cell and a throughput of up to 35 Gb per day. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology.
http://purl.obolibrary.org/obo/OBI_0002023	Human Genome U133 Plus 2.0 tiling array	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	Affymetrix HT Human Genome U133 Plus 2 Array Plate Set	A tiling array which is  a comprehensive whole human genome expression array manufactured by the Affymetrix corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 47,000 transcripts and variants.
http://purl.obolibrary.org/obo/OBI_0002024	SOLiD 4 System	http://purl.obolibrary.org/obo/OBI_0000696	AB SOLiD System	SOLiD 4	An AB SOLid System which is manufacted by the Applied Biosystems corporation. Built upon SOLiD sequencing technology, the machine generates greater than 1 billion mappable reads per run.
http://purl.obolibrary.org/obo/OBI_0002025	Human Exon 1.0 ST tilling array	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	Human Exon 1.0 ST Array	A tiling microarray which is manufactured by the Affymetrix corporation. Built to analyze 3' DNA sequence copy number by comparative genomic hybridization for human DNA against 28,000 genes. It  can be used for gene expression and alternative splicing assay
http://purl.obolibrary.org/obo/OBI_0002026	Human Genome U133 tiling array	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	HG-U133 array	A tiling array which is manufactured by the Affymetrix corporation. Built to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 39,000 transcripts and variants.
http://purl.obolibrary.org/obo/OBI_0002027	Illumina Genome Analyzer IIe	http://purl.obolibrary.org/obo/OBI_0000703	Illumina Genome Analyzer II	Illumina GA IIe	An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIe makes industry-leading next-generation sequencing technology accessible to more laboratories.
http://purl.obolibrary.org/obo/OBI_0002029	serial analysis of gene expression assay	http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay	SAGE	A transcription profiling assay that quantifies RNA through creating short signature tags of the messages and ligating them into a larger molecule than was sequenced.
http://purl.obolibrary.org/obo/OBI_0002030	genotyping by tiling array assay	http://purl.obolibrary.org/obo/OBI_0001274	genotyping by array assay	DNA sequence variation detection by tiling array	A genotyping by array assay that uses tiling array technology.
http://purl.obolibrary.org/obo/OBI_0002031	genotyping by SNP array assay	http://purl.obolibrary.org/obo/OBI_0001274	genotyping by array assay	DNA sequence variation detection by snp array	A genotyping by array assay that uses SNP array technology.
http://purl.obolibrary.org/obo/OBI_0002032	parallel analysis of RNA structure assay	http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	PARS	A single-nucleotide-resolution nucleic acid structure mapping assay that performs simultaneous in vitro profiling of the secondary structure of thousands of RNA species at single nucleotide resolution using enzymatic probing based on deep sequencing fragments of RNAs that were treated with structure-specific enzymes
http://purl.obolibrary.org/obo/OBI_0002033	translation-associated transcript leader sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	TATL-seq	An RNA-seq assay that combines TL-seq with polysome fractionation
http://purl.obolibrary.org/obo/OBI_0002034	transcript leader sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	TL-seq	An RNA-seq assay that combines enzymatic capture of m(7)G-capped mRNA 5' ends with high-throughput sequencing.
http://purl.obolibrary.org/obo/OBI_0002035	peptide mass fingerprinting assay	http://purl.obolibrary.org/obo/OBI_0000470	mass spectrometry assay	protein fingerprinting	A mass spectrometry assay that measures the absolute mass of the cleaved peptides derived from an unknown protein of interest. These masses are then compared to values for known protein sequences to identify the unknown protein.
http://purl.obolibrary.org/obo/OBI_0002038	ribosomal profiling by sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	ribosomal profiling	A RNA-seq assay that sequences only mRNA protected by the ribosome during translation.
http://purl.obolibrary.org/obo/OBI_0002039	assay for transposase-accessible chromatin using sequencing	http://purl.obolibrary.org/obo/OBI_0003686	chromatin accessibility assay	ATAC-seq assay	An assay to capture the location of open chromatin, DNA-binding proteins, individual nucleosomes and chromatin compaction at nucleotide resolution by Tn5 transposase insertion.
http://purl.obolibrary.org/obo/OBI_0002040	chromatin isolation by RNA purification sequencing assay	http://purl.obolibrary.org/obo/OBI_0000874	detection of specific nucleic acid polymers with complementary probes	Chromatin Isolation by RNA purification	A detection of specific nucleic acids with complementary probes assay that measures regions of the genome which are bound by a specific RNA (or a by a ribonucleoprotein containing the RNA of interest) using high-throughput sequencing.
http://purl.obolibrary.org/obo/OBI_0002041	self-transcribing active regulatory region sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	STARR-seq assay	An RNA-seq assay that identifies the sequences that act as transcriptional enhancers in a direct, quantitative, and genome-wide manner from sheared genomic DNA.
http://purl.obolibrary.org/obo/OBI_0002042	carbon-copy chromosome conformation capture assay followed by sequencing assay	http://purl.obolibrary.org/obo/OBI_0001919	Carbon-copy chromosome conformation capture assay	Carbon-copy chromosome conformation capture assay followed by sequencing	A carbon-copy chromosome conformation capture assay to analyze the organization of chromosomes in an unbiased, genome-wide manner using high throughput sequening following carbon-copy chromosome conformation capture.
http://purl.obolibrary.org/obo/OBI_0002043	individual-nucleotide resolution cross-linking and immunoprecipitation sequencing assay	http://purl.obolibrary.org/obo/OBI_0001858	cross-linking immunoprecipitation high-throughput sequencing assay	iCLIP assay	A cross-linking immunoprecipitation high-throughput sequencing assay that identifies protein-RNA interactions using UV light to covalently bind proteins and RNA molecules, allowing for a very stringent purification of the linked protein-RNA complexes.
http://purl.obolibrary.org/obo/OBI_0002044	RNA Bind-n-Seq assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	RNBS assay	An RNA-seq assay that comprehensively characterizes sequence and structural specificity of RNA binding proteins (RBPs).
http://purl.obolibrary.org/obo/OBI_0002045	polyA-site sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	poly(A)-site sequencing assay	A RNA-seq assay that quantitatively profiles RNA polyadenylation at the transcriptome level.
http://purl.obolibrary.org/obo/OBI_0002046	surface plasmon resonance sensor chip	http://purl.obolibrary.org/obo/OBI_0000968	device	sensor chip	A device that is used as a binding surface for ligand during a surface plasmon resonance assay, consisting of a glass plate to which a metal film is attached
http://purl.obolibrary.org/obo/OBI_0002048	Illumina HiSeq 3000	http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	HiSeq 3000	A DNA sequencer manufactured by Illumina corporation, with a single flow cell and a throughput of more than 200 Gb per day.
http://purl.obolibrary.org/obo/OBI_0002049	Illumina HiSeq 4000	http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	HiSeq 4000	A DNA sequencer manufactured by Illumina corporation, with two flow cell and a throughput of more than 400 Gb per day.
http://purl.obolibrary.org/obo/OBI_0002077	specimens derived from shared ancestor	http://purl.obolibrary.org/obo/OBI_0002076	collection of specimens	specimen family	A collection of specimens derived from one common specimen via one or more material processing process(es).
http://purl.obolibrary.org/obo/OBI_0002079	specimens collected in one encounter	http://purl.obolibrary.org/obo/OBI_0002076	collection of specimens	specimen set	A collection of specimens that is collected from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.
http://purl.obolibrary.org/obo/OBI_0002082	reporter gene assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	reporter gene detection assay	An assay that detects expression of a reporter gene that was inserted under the control of a regulatory sequence of interest.
http://purl.obolibrary.org/obo/OBI_0002083	enhancer activity detection by reporter gene assay	http://purl.obolibrary.org/obo/OBI_0002082	reporter gene assay	enhancer reporter gene assay	A reporter gene assay that detects expression of a reporter gene that was inserted under the control of an enhancer of interest.
http://purl.obolibrary.org/obo/OBI_0002084	transcription cofactor activity region identification by ChIP-Seq assay	http://purl.obolibrary.org/obo/OBI_0000716	ChIP-seq assay	chromatin modifier binding site identification by ChIP-Seq assay	A ChIP-seq assay that identifies regions of chromatin bound to a chromatin modifying protein, e.g. a histone acetyltransferase.
http://purl.obolibrary.org/obo/OBI_0002085	transcript expression location detection by hybridization chain reaction assay	http://purl.obolibrary.org/obo/OBI_0001686	in-situ hybridization assay	transcript expression location detection by fluorescent HCR.	An in situ hybridization assay in which the location (e.g. anatomical/tissue) of a transcript is detected by a multiplexed fluorescent in situ hybridization, based on orthogonal amplification with hybridization chain reactions (HCR). RNA probes complementary to mRNA targets trigger chain reactions in which fluorophore-labeled RNA hairpins self-assemble into tethered fluorescent amplification polymers.
http://purl.obolibrary.org/obo/OBI_0002086	Tet-assisted bisulfite sequencing assay	http://purl.obolibrary.org/obo/OBI_0000748	bisulfite sequencing assay	Tet-assisted bisulfite sequencing	A bisulfite sequencing assay that identifies genomic methylation patterns by using a bisulfite based protocol with the Tet enzyme to differentiate 5-hydroxylmethylcytosine (5hmC) from 5-methylcytosine (5mC) through a step-wise oxidative demethylation of 5mC, converting it to 5-carboxylcytosine (5caC) while keeping 5hmC protected.
http://purl.obolibrary.org/obo/OBI_0002090	rapid amplification of cDNA ends	http://purl.obolibrary.org/obo/OBI_0000552	reverse transcribed polymerase chain reaction	RACE	A reverse transcribed polymerase chain reaction that is used to amplify a mRNA sequence between a defined internal site and the 5' or 3' end of the mRNA.
http://purl.obolibrary.org/obo/OBI_0002091	5' rapid amplification of cDNA ends	http://purl.obolibrary.org/obo/OBI_0002090	rapid amplification of cDNA ends	5' RACE	A rapid amplication of cDNA ends to amplify a mRNA sequence between a defined internal site and the 5' end of the mRNA.
http://purl.obolibrary.org/obo/OBI_0002092	3' rapid amplification of cDNA ends	http://purl.obolibrary.org/obo/OBI_0002090	rapid amplification of cDNA ends	3' RACE	A rapid amplication of cDNA ends to amplify a mRNA sequence between a defined internal site and the 3' end of the mRNA.
http://purl.obolibrary.org/obo/OBI_0002093	5' RNA ligase mediated rapid amplification of cDNA ends	http://purl.obolibrary.org/obo/OBI_0002091	5' rapid amplification of cDNA ends	5' RLM RACE	A 5' rapid amplification pf cDNA ends that uses RNA ligase to add an RNA adapter oligonucleotide to intact 5' mRNA ends, allowing the amplification of cDNA only from full-length, capped mRNA.
http://purl.obolibrary.org/obo/OBI_0002094	MethylC-Capture sequencing assay	http://purl.obolibrary.org/obo/OBI_0000748	bisulfite sequencing assay	MethylC-Capture Sequencing	A bisulfite sequencing assay in which a whole-genome sequencing library is prepared, bisulfite converted and amplified, followed by a capture enriching for targeted bisulfite-converted DNA fragments that are are subsequently identified by DNA sequencing.
http://purl.obolibrary.org/obo/OBI_0002106	carboxyfluorescein succinimidyl ester staining assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	CFSE assay	An assay using carboxyfluorescein succinimidyl ester staining.
http://purl.obolibrary.org/obo/OBI_0002107	bio-layer interferometry assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay	biolayer interferometry, BLI	A binding assay that detects a shift in the interference pattern reflected from a layer of immobilized material on the biosensor tip to measure binding to- or dissociating from the material on the biosensor.
http://purl.obolibrary.org/obo/OBI_0002108	small-angle scattering 3D molecular structure determination assay	http://purl.obolibrary.org/obo/OBI_0003117	3D molecular structure determination assay	SAXS	A 3D molecular structure determination assay in which the scattering pattern of a neutron or x-ray beam targeted at a material entity is recorded at small angles relative to the incident beam to determine the size, shape and structure of the material entity examined.
http://purl.obolibrary.org/obo/OBI_0002109	Human 6x630K CGH Whole Genome Tiling Array	http://purl.obolibrary.org/obo/OBI_0001307	tiling microarray	NimbleGen Human 6x630K CGH Whole Genome Tiling Array	A tiling array which is manufactured by the Nimblegen corporation to analyze DNA sequence copy number by comparative genomic hybridization for human DNA against 6x630,000 features.
http://purl.obolibrary.org/obo/OBI_0002110	digital object identifier	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol	DOI	A centrally registered identifier symbol used to uniquely identify objects given by International DOI Foundation. The DOI system is particularly used for electronic documents such as journal articles.
http://purl.obolibrary.org/obo/OBI_0002111	enhanced cross-linking immunoprecipitation high-throughput sequencing assay	http://purl.obolibrary.org/obo/OBI_0002043	individual-nucleotide resolution cross-linking and immunoprecipitation sequencing assay	eCLIP	An iCLIP assay that is enhanced to robustly identify protein-RNA interactions with high efficiency through improvements in library preparation of RNA fragments.
http://purl.obolibrary.org/obo/OBI_0002112	small RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	short RNA-seq	An RNA-seq assay which is targeting small RNA (< 200 bp) sequences such as, but not exclusive to, miRNAs using, for example, small RNA library preparation kits.
http://purl.obolibrary.org/obo/OBI_0002113	bromouridine labeling and sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	Bru-seq	An RNA-seq assay to identify spans of nascent transcription in the genome through isolation of recent bromouridine (Bru) labelled RNAs.
http://purl.obolibrary.org/obo/OBI_0002114	bromouridine pulse-chase and sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	BruChase-seq	An RNA-seq assay to identify RNA populations of specific ages through isolation of RNAs first labelled with bromouridine (Bru) followed by chasing in uridine for different periods of time.
http://purl.obolibrary.org/obo/OBI_0002115	cytometry time of flight assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay	mass cytometry assay	A cytometry assay in which the presence of molecules of interest on or in cells is indicated by binding of antibodies labeled with rare earth element tags which are detected by time-of-flight mass spectrometry.
http://purl.obolibrary.org/obo/OBI_0002116	high performance liquid chromotography assay	http://purl.obolibrary.org/obo/OBI_0001630	analytical chromatography	HPLC	An analytical chromatography assay that utilizes a high performance liquid chromatography instrument for separation of compounts in a solution.
http://purl.obolibrary.org/obo/OBI_0002117	whole genome sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	WGS	A DNA sequencing assay that intends to provide information about the sequence of an entire genome of an organism.
http://purl.obolibrary.org/obo/OBI_0002118	exome sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	WES	A DNA sequencing assay that intends to provide information about the sequence of the protein coding components of a genome (exons).
http://purl.obolibrary.org/obo/OBI_0002120	mixed lymphocyte reaction assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay	MLR	A cytometry assay where lymphocytes from two individuals are co-cultured with the lymphocytes from one of the allogeneic individuals (Responders) being labeled (with 3H Thymidine or BrdU) and the proliferation of the labeled cells is measured, which is thought to reflect recognition of histocompatibility antigens on the unlabeled cells (stimulators).
http://purl.obolibrary.org/obo/OBI_0002121	killer cell immunoglobulin-like receptor typing assay	http://purl.obolibrary.org/obo/OBI_0000435	genotyping assay	KIR typing	A genotyping assay in which the alleles of genes encoding for killer cell immunoglobulin-like receptors are determined.
http://purl.obolibrary.org/obo/OBI_0002122	major histocompatibility typing assay	http://purl.obolibrary.org/obo/OBI_0000435	genotyping assay	MHC typing, HLA typing	A genotyping assay in which the alleles of genes encoding for major histocompatibility complex molecules are determined.
http://purl.obolibrary.org/obo/OBI_0002503	feces specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism	stool specimen	A specimen that is derived from feces.
http://purl.obolibrary.org/obo/OBI_0002504	digestive system fluid or secretion specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen	gastric fluid specimen	A specimen that is derived from digestive system fluid or secretion.
http://purl.obolibrary.org/obo/OBI_0002511	vitreous humor specimen	http://purl.obolibrary.org/obo/OBI_2000004	eye specimen	vitreous fluid specimen	A specimen that is derived from vireous humor.
http://purl.obolibrary.org/obo/OBI_0002521	renal medulla specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism	kidney medulla specimen	A specimen that is derived from renal medulla.
http://purl.obolibrary.org/obo/OBI_0002523	breast specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism	mammary tissue specimen	A specimen that is derived from breast.
http://purl.obolibrary.org/obo/OBI_0002526	skin of body specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism	skin specimen	A specimen that is derived from skin.
http://purl.obolibrary.org/obo/OBI_0002531	cortex of kidney specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism	kidney cortex specimen	A specimen that is derived from cortex of kidney.
http://purl.obolibrary.org/obo/OBI_0002535	esophagus muscularis mucosa specimen	http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen	esophagus muscularis specimen	A specimen that is derived from esophagus muscularis mucosa.
http://purl.obolibrary.org/obo/OBI_0002536	cerebral cortex specimen	http://purl.obolibrary.org/obo/OBI_0002516	brain specimen	brain cortex specimen	A specimen that is derived from cerebral cortex.
http://purl.obolibrary.org/obo/OBI_0002538	cerebellum specimen	http://purl.obolibrary.org/obo/OBI_0002516	brain specimen	brain cerebellum specimen	A specimen that is derived from cerebellum.
http://purl.obolibrary.org/obo/OBI_0100016	blood plasma specimen	http://purl.obolibrary.org/obo/OBI_0000953	processed specimen	plasma	a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended.
http://purl.obolibrary.org/obo/OBI_0100046	phosphate buffered saline solution	http://purl.obolibrary.org/obo/OBI_0302729	chemical solution	PBS buffer	Phosphate buffered saline (abbreviated PBS) is a buffer solution commonly used in biochemistry. It is a salty solution containing sodium chloride, sodium phosphate and in some preparations potassium chloride and potassium phosphate. The buffer helps to maintain a constant pH. The concentration usually matches the human body (isotonic).
http://purl.obolibrary.org/obo/OBI_0100056	obsolete_immortal cell line culture	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	permanent cell line	A cell line that is expected to be capable of indefinite propagation in an vitro culture.
http://purl.obolibrary.org/obo/OBI_0100058	xenograft	http://purl.obolibrary.org/obo/OBI_0000047	processed material	xenotransplant	A material entity which results from the transplantation of living cells, tissues or organs  from on organism of one species to an organism of another species.
http://purl.obolibrary.org/obo/OBI_0100060	cultured cell population	http://purl.obolibrary.org/obo/OBI_0000047	processed material	cell culture sample	A processed material comprised of a collection of cultured cells that has been continuously maintained together in culture and shares a common propagation history.
http://purl.obolibrary.org/obo/OBI_0100061	primary cultured cell population	http://purl.obolibrary.org/obo/OBI_0100060	cultured cell population	primary cell culture sample	A cultured cell population comprised of cells expanded directly from living tissue prior to being passaged.
http://purl.obolibrary.org/obo/OBI_0100062	obsolete_cell line	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	cell line sample	A secondary cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (ie has been successively passaged together in culture).
http://purl.obolibrary.org/obo/OBI_0100063	cultured clonal cell population	http://purl.obolibrary.org/obo/OBI_0100060	cultured cell population	clonal cell culture sample	A cultured cell population comprised of cells which can all be traced back to a single ancestor cell, and which therefore can be treated as identical.
http://purl.obolibrary.org/obo/OBI_0100067	bronchial alveolar lavage	http://purl.obolibrary.org/obo/OBI_0003666	lavage fluid specimen	BAL	Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space.
http://purl.obolibrary.org/obo/OBI_0100086	glucose in solution	http://purl.obolibrary.org/obo/BFO_0000040	material entity	glucose molecules	A scattered aggregate of glucose molecules in a liquid
http://purl.obolibrary.org/obo/OBI_0200000	data transformation	http://purl.obolibrary.org/obo/OBI_0000011	planned process	data processing	A planned process that produces output data from input data.
http://purl.obolibrary.org/obo/OBI_0200022	variance stabilizing transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation	variance stabilising transformation	A variance stabilizing transformation is a data transformation, described in PMID 12169536, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (6) in this paper. One of the goals is to obtain an output matrix whose rows have equal variances. The method relies on various assumptions described in the paper.
http://purl.obolibrary.org/obo/OBI_0200029	mean centering	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation	mean centring	A mean centering is a data transformation that takes as input an n-dimensional (real) vector, performs a mean calculation on its components, and subtracts the resulting mean from each component of the input.
http://purl.obolibrary.org/obo/OBI_0200030	median centering	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation	median centring	A median centering is a data transformation that takes as input an n-dimensional (real) vector, performs a median calculation on its components, and subtracts the resulting median from each component of the input.
http://purl.obolibrary.org/obo/OBI_0200034	jackknifing method	http://purl.obolibrary.org/obo/OBI_0000792	statistical model validation	jackknifing	Jacknifing is a re-sampling data transformation process used to estimate the precision of sampling statistics and is a resampling method
http://purl.obolibrary.org/obo/OBI_0200050	dimensionality reduction	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation	data projection	A dimensionality reduction is data partitioning which transforms each input m-dimensional vector (x_1, x_2, ..., x_m) into an output n-dimensional vector (y_1, y_2, ..., y_n), where n is smaller than m.
http://purl.obolibrary.org/obo/OBI_0200051	principal components analysis dimensionality reduction	http://purl.obolibrary.org/obo/OBI_0200050	dimensionality reduction	pca data reduction	A principal components analysis dimensionality reduction is a dimensionality reduction achieved by applying principal components analysis and by keeping low-order principal components and excluding higher-order ones.
http://purl.obolibrary.org/obo/OBI_0200064	centroid mass spectrum analysis	http://purl.obolibrary.org/obo/OBI_0200085	mass spectrometry analysis	centroiding	A centroid mass spectrum is a data transformation in which many points are used to delineate a mass spectral peak, is converted into mass-centroided data by a data compression algorithm. The centroided mass peak is located at the weighted center of mass of the profile peak. The normalized area of the peak provides the mass intensity data.
http://purl.obolibrary.org/obo/OBI_0200073	family wise error rate correction method	http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	FWER correction	A family wise error rate correction method is a multiple testing procedure that controls the probability of at least one false positive.
http://purl.obolibrary.org/obo/OBI_0200080	network analysis	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	network topology analysis	A data transformation that takes as input data that describes biological networks in terms of the node (a.k.a. vertex) and edge graph elements and their characteristics and generates as output properties of the constituent nodes and edges, the sub-graphs, and the entire network.
http://purl.obolibrary.org/obo/OBI_0200082	longitudinal data analysis	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	correlation analysis	Longitudinal analysis is a data transformation used to perform repeated observations of the same items over long periods of time.
http://purl.obolibrary.org/obo/OBI_0200083	survival analysis objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	survival analysis	A data transformation objective which has the data transformation aims to model time to event data (where events are e.g. death and or disease recurrence); the purpose of survival analysis is to model the underlying distribution of event times and to assess the dependence of the event time on other explanatory variables
http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	http://purl.obolibrary.org/obo/OBI_0000668	error correction data transformation	multiple testing procedure	A multiple testing correction method is a hypothesis test performed simultaneously on M > 1 hypotheses.  Multiple testing procedures produce a set of rejected hypotheses that is an estimate for the set of false null hypotheses while controlling for a suitably define Type I error rate
http://purl.obolibrary.org/obo/OBI_0200091	inter-rater reliability objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	inter-rater agreement	a data transformation objective of determining the concordance or agreement between human judges.
http://purl.obolibrary.org/obo/OBI_0200092	Westfall and Young family wise error rate correction	http://purl.obolibrary.org/obo/OBI_0200073	family wise error rate correction method	Westfall and Young FWER correction	Is a data transformation process in which the Westfall and Young method is applied with the aim of controlling for multiple testing
http://purl.obolibrary.org/obo/OBI_0200098	soft independent modeling of class analogy analysis	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation	SIMCA	Soft independent modeling by class analogy (SIMCA) is a descriptive statistics method for supervised classification of data. The method requires a training data set consisting of samples (or objects) with a set of attributes and their class membership. The term soft refers to the fact the classifier can identify samples as belonging to multiple classes and not necessarily producing a classification of samples into non-overlapping classes.
http://purl.obolibrary.org/obo/OBI_0200100	canonical variate analysis	http://purl.obolibrary.org/obo/OBI_0200171	partitioning data transformation	CVA	canonical variate analysis is a form of discriminant analysis that takes several continuous predictor variables and uses the entire set to predict several criterion variables, each of which is also continuous. CVA simultaneously calculates a linear composite of all x variables and  a linear composite of all y variables. Unlike other multivariate techniques, these weighted composites are derived in pairs. Each linear combination is called a canonical variate and takes the general linear form.
http://purl.obolibrary.org/obo/OBI_0200105	partial least square regression analysis	http://purl.obolibrary.org/obo/OBI_0200102	regression analysis method	PLS-RA	Partial least squares regression is an extension of the multiple linear regression model (see, e.g., Multiple Regression or General Stepwise Regression). In its simplest form, a linear model specifies the (linear) relationship between a dependent (response) variable Y, and a set of predictor variables, the X's, so that
Y = b0 + b1X1 + b2X2 + ... + bpXp
In this equation b0 is the regression coefficient for the intercept and the bi values are the regression coefficients (for variables 1 through p) computed from the data.
http://purl.obolibrary.org/obo/OBI_0200107	partial least square discriminant analysis	http://purl.obolibrary.org/obo/OBI_0200106	discriminant analysis	PLS-DA	PLS Discriminant Analysis (PLS-DA) is a discriminant analysis performed in order to sharpen the separation between groups of observations, by hopefully rotating PCA (Principal Components Analysis) components such that a maximum separation among classes is obtained, and to understand which variables carry the class separating information.
http://purl.obolibrary.org/obo/OBI_0200111	data visualization	http://purl.obolibrary.org/obo/OBI_0000011	planned process	data encoding as image	A planned process with the objective to graphically represent some data by inputing the data and outputting images, diagrams or animations.
http://purl.obolibrary.org/obo/OBI_0200125	data combination	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	data pooling	A data transformation in which individual input data elements and values are merged together into a output set of data elements and values.
http://purl.obolibrary.org/obo/OBI_0200141	log base	http://purl.obolibrary.org/obo/OBI_0200140	mathematical feature	logarithmic base	The log base is a feature of a logarithmic function which is defined in http://en.wikipedia.org/wiki/Logarithm. Its value can be any positive real number different from 1.
http://purl.obolibrary.org/obo/OBI_0200149	unit-variance scaling	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation	autoscaling	A unit-variance scaling is a data transformation that divides all measurements of a variable by the standard deviation of that variable.
http://purl.obolibrary.org/obo/OBI_0200154	agglomerative hierarchical clustering	http://purl.obolibrary.org/obo/OBI_0200042	hierarchical clustering	bottom-up hierarchical clustering	An agglomerative hierarchical clustering is a hierarchical clustering which starts with separate clusters and then successively combines these clusters until there is only one cluster remaining.
http://purl.obolibrary.org/obo/OBI_0200155	divisive hierarchical clustering	http://purl.obolibrary.org/obo/OBI_0200042	hierarchical clustering	top-down hierarchical clustering	A divisive hierarchical clustering is a hierarchical clustering which starts with a single cluster and then successively splits resulting clusters until only clusters of individual objects remain.
http://purl.obolibrary.org/obo/OBI_0200160	generalized family wise error rate correction method	http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	gFWER correction	A generalized FWER correction method is a multiple testing procedure that controls the probability of at least k+1 false positives, where k is a user-supplied integer.
http://purl.obolibrary.org/obo/OBI_0200161	quantile number of false positives correction method	http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	QNFP	A quantile number of false positives correction method is a MTP that controls for the pth quantile of the distribution of the number of false positives out of the total number of tests performed'
http://purl.obolibrary.org/obo/OBI_0200162	tail probability for the proportion of false positives correction method	http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	TPPFP correction method	A TPPFP correction method is a MTP that controls the probability that the proportion of false positives among all rejected hypotheses is no greater than a constant q, where q is between 0 and 1.
http://purl.obolibrary.org/obo/OBI_0200163	false discovery rate correction method	http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	FDR correction method	The false discovery rate is a  data transformation used in multiple hypothesis testing to correct for multiple comparisons. It controls the expected proportion of incorrectly rejected null hypotheses (type I errors) in a list of rejected hypotheses. It is a less conservative comparison procedure with greater power than familywise error rate (FWER) control, at a cost of increasing the likelihood of obtaining type I errors. .
http://purl.obolibrary.org/obo/OBI_0200164	proportion of expected false positives correction method	http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	PEFP correction method	A proportion of expected false positives correction method is a multiple testing procedure that controls the ratio of the expected value of the numbers of false positives to the expected value of the numbers of rejected hypotheses.
http://purl.obolibrary.org/obo/OBI_0200165	quantile proportion of false positives correction method	http://purl.obolibrary.org/obo/OBI_0200089	multiple testing correction method	QPFP correction method	A quantile proportion of false positives correction method is a multiple testing procedure that controls the pth quantile of the distribution of the proportion of false positives among the rejected hypothesis (false discovery rate).
http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation	unsupervised classification data transformation	A class discovery data transformation (sometimes called unsupervised classification) is a data transformation that has objective class discovery.
http://purl.obolibrary.org/obo/OBI_0200178	class discovery objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	clustering objective	A class discovery objective (sometimes called unsupervised classification) is a data transformation objective where the aim is to organize input data  (typically vectors of attributes) into classes, where the number of classes and their specifications are not known a priori. Depending on usage, the class assignment can be definite or probabilistic.
http://purl.obolibrary.org/obo/OBI_0200179	class prediction objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	classification objective	A class prediction objective (sometimes called supervised classification) is a data transformation objective where the aim is to create a predictor from training data through a machine learning technique. The training data consist of pairs of objects (typically vectors of attributes) and
class labels for these objects. The resulting predictor can be used to attach class labels to any valid novel input object. Depending on usage, the prediction can be definite or probabilistic. A classification is learned from the training data and can then be tested on test data.
http://purl.obolibrary.org/obo/OBI_0200188	cross validation objective	http://purl.obolibrary.org/obo/OBI_0200172	partitioning objective	rotation estimation objective	A cross validation objective is a data transformation objective in which the aim is to partition a sample of data into subsets such that the analysis is initially performed on a single subset, while the other subset(s) are retained for subsequent use in confirming and validating the initial analysis.
http://purl.obolibrary.org/obo/OBI_0200189	merging objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	combining objective	A merging objective is a data transformation objective in which the data transformation has the aim of performing a union of two or more sets.
http://purl.obolibrary.org/obo/OBI_0200195	proportional hazards model estimation	http://purl.obolibrary.org/obo/OBI_0200194	survival analysis data transformation	Cox proportional hazards model	Proportional hazards model is a data transformation model to estimate the effects of different covariates influencing the times-to-failure of a system.
http://purl.obolibrary.org/obo/OBI_0302714	obsolete_collection (of entities of organismal origin)	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	set	a collection is a bfo:aggregate object, that is a set of material object of the same kind
http://purl.obolibrary.org/obo/OBI_0302729	chemical solution	http://purl.obolibrary.org/obo/BFO_0000040	material entity	liquid chemical solution	A material entity  that is made up of at least 2 scattered molecular aggregates, one playing the role of solvent and the other one playing the role of solute.
http://purl.obolibrary.org/obo/OBI_0302731	buffer role	http://purl.obolibrary.org/obo/BFO_0000023	role	buffer	a role which inheres in some molecular entity realized during the process of buffering
http://purl.obolibrary.org/obo/OBI_0302736	comet assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay	single cell gel electrophoresis assay	An assay that measures DNA damage (DNA breakage) in eucaryotic cells exposed to a challenge by determining the size and shape of DNA migration by detecting fluorescently labeled DNA from a cell placed in an electric field using gel electrophoresis
http://purl.obolibrary.org/obo/OBI_0302737	PCR-SSCP assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	polymerase chain reaction-single strand conformation polymorphism assay	An assay that identifies DNA sequence variation (mutation, deletion, insertions) in target DNA sequences amplified using polymerase chain reaction using gel electrophoresis and denaturating conditions
http://purl.obolibrary.org/obo/OBI_0302898	intentional overdosing	http://purl.obolibrary.org/obo/OBI_0000919	animal euthanization	lethal injection	intentional overdosing is a process by which an excess dose of a chemical compound is given with the intent of causing death
http://purl.obolibrary.org/obo/OBI_0302912	electroporation	http://purl.obolibrary.org/obo/OBI_0600033	cell permeabilization	electropermeabilization	a process in which a significant increase in the electrical conductivity and permeability of the cell plasma membrane caused by an externally applied electrical field. It is usually used in molecular biology as a way of introducing some substance into a cell, such as loading it with a molecular probe, a drug that can change the cell's function, or a piece of coding DNA
http://purl.obolibrary.org/obo/OBI_0400007	analog-to-digital converter	http://purl.obolibrary.org/obo/OBI_0000968	device	A2D	An analog-to-digital_converter is an instrument that converts an infinite resolution analog signal to a finite resolution digital signal.
http://purl.obolibrary.org/obo/OBI_0400043	flow cell	http://purl.obolibrary.org/obo/OBI_0000967	container	flow_cell	Aparatus in the fluidic subsystem where the sheath and sample meet. Can be one of several types; jet-in-air, quartz cuvette, or a hybrid of the two. The sample flows through the center of a fluid column of sheath fluid in the flow cell.
http://purl.obolibrary.org/obo/OBI_0400050	Guava Personal Cell Analysis	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer	Guava_PCA	A  Guava_Personal_Cell_Analysis System is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses only tubes to introduce specimen. The Guava PCA cytometer is a small portable cytometer particularly useful for field measurement.
http://purl.obolibrary.org/obo/OBI_0400051	Guava Personal Cell Analysis-96	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer	Guava_PCA-96	The Guava_Personal_Cell_Analysis-96 Systems is a flow_cytometer_analyser that includes a single 532 nm laser, and filters and PMTs to collect up to 2 fluorescent parameters. It includes a photodiode forward scatter collector. Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The PCA96 uses either tubes or 96 well plates to introduce specimen. The Guava PCA -96 cytometer is a small portable cytometer particularly useful for field measurement.
http://purl.obolibrary.org/obo/OBI_0400064	laser	http://purl.obolibrary.org/obo/OBI_0400065	light source	light amplification by the stimulated emission of radiation	A laser (acronym for light amplification by the stimulated emission of radiation) is a light source that emits photons of the same characteristics in a coherent beam. A laser uses a solid, liquid or gaseous lasing medium, that contains molecules, of which some atoms have electrons that emit photons of the same frequency when falling back to their normal orbital after excitation (pumping) by external means A laser is the most common way to irradiate a cell in a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0400112	liquid handler	http://purl.obolibrary.org/obo/OBI_0000968	device	liquid_handling_instrument	A device that is used for automated liquid transfer and handling.
http://purl.obolibrary.org/obo/OBI_0400116	thermal cycler	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control	thermocycler	An instrument that is capable of repeatedly altering and maintaining specific temperatures for defined periods of time.
http://purl.obolibrary.org/obo/OBI_0400118	vortexer	http://purl.obolibrary.org/obo/OBI_0001033	perturbation device	vortex_mixer	A vortexer is an instrument that mixes small vials of liquid by creating a rotation of the liquid around its own center. It consists of an electric motor with the drive shaft oriented vertically and attached to a cupped rubber piece mounted slightly off-center. As the motor runs the rubber piece oscillates rapidly in a circular motion. When a test tube or other appropriate container is pressed into the rubber cup (or touched to its edge) the motion is transmitted to the liquid inside and a vortex is created.
http://purl.obolibrary.org/obo/OBI_0400121	molecular crosslinker	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device	molecular crosslinker	A device that is able to chemically join two or more molecules.
http://purl.obolibrary.org/obo/OBI_0400140	gel tank	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control	electrophoresis unit	A device which holds a gel and running buffers to allow electrophoresis to be performed. A gel tank has the function to contain and to control the contained environment and transfer energy from an energy supply through the running buffers to the gel matrix and the material with charged molecules in an electric field across a porous matrix or medium with the objective to separate the charged molecules.
http://purl.obolibrary.org/obo/OBI_0400142	power supply	http://purl.obolibrary.org/obo/OBI_0000968	device	power supply unit	A power supply is an device or part of a device that permits the required application of a defined electrical charge to an instrument. The power supply may permit the defined application of a given amount of current for a defined length of time.
http://purl.obolibrary.org/obo/OBI_0400146	multispectral imaging flow cytometer	http://purl.obolibrary.org/obo/OBI_0000398	image creation device	MIFC	A multispectral_imaging_flow_cytometer is an instrument which combines quantitative image analysis and flow cytometry in a single platform. It measures the amount, location and movement of molecules on, in, or between cells, and  the location and co-localization of multiple markers on or in cells. It can also quantitate morphologically distinct cell subpopulations.
http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	http://purl.obolibrary.org/obo/OBI_0400147	microarray	DNA-array	A DNA-microarray is a microarray that is used as a physical 2D immobilisation matrix for DNA sequences. DNA microarray-bound DNA fragments are used as targets for a hybridising probed sample.
http://purl.obolibrary.org/obo/OBI_0400171	animal cage	http://purl.obolibrary.org/obo/OBI_0000967	container	laboratory cage	A processed material which has the function to define a bounded habitat which is amenable to keeping animals.
http://purl.obolibrary.org/obo/OBI_0500000	study design	http://purl.obolibrary.org/obo/IAO_0000104	plan specification	experimental design	A plan specification comprised of protocols (which may specify how and what kinds of data will be gathered) that are executed as part of an investigation and is realized during a study design execution.
http://purl.obolibrary.org/obo/OBI_0500006	parallel group design	http://purl.obolibrary.org/obo/OBI_0500000	study design	independent measure design	A parallel group design or independent measure design is a study design which uses unique experimental unit each experimental group, in other word no two individuals are shared between experimental groups, hence also known as parallel group design. Subjects of a treatment group receive a unique combination of independent variable values making up a treatment
http://purl.obolibrary.org/obo/OBI_0500026	eligibility criterion	http://purl.obolibrary.org/obo/OBI_0001755	selection criterion	eligibility rule	an eligibility criterion (rule) is_a selection criterion which 
defines and states the requirements (positive or negative) for an entity to be considered as suitable for a given task or participation in a process.
http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500026	eligibility criterion	inclusion rule	an inclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity suitable for a given task or participation in a given process. For instance, in a study protocol, inclusion criteria indicate the conditions that prospective subjects MUST meet to be eligible for participation in a study.
http://purl.obolibrary.org/obo/OBI_0600002	tumor grading	http://purl.obolibrary.org/obo/OBI_0000070	assay	grading of tumor	An assay that determines the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus.
http://purl.obolibrary.org/obo/OBI_0600003	obsolete performing a clinical assessment	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	clinical diagnosis	A protocol application during which a series of tests are made of a patient leading to determination of disease state, or condition.
http://purl.obolibrary.org/obo/OBI_0600006	killing	http://purl.obolibrary.org/obo/OBI_0000094	material processing	sacrifice	A protocol application in which an organism is intentionally put to death
http://purl.obolibrary.org/obo/OBI_0600010	material acquisition	http://purl.obolibrary.org/obo/OBI_0600008	acquisition	material procurement	An acquisition in which possession of a material entity is gained.
http://purl.obolibrary.org/obo/OBI_0600013	information acquisition	http://purl.obolibrary.org/obo/OBI_0600008	acquisition	data collection	An acquisition in which possession of information is gained.
http://purl.obolibrary.org/obo/OBI_0600015	group assignment	http://purl.obolibrary.org/obo/OBI_0000011	planned process	study assignment	group assignment is a process which has an organism as specified input and during which a role is assigned
http://purl.obolibrary.org/obo/OBI_0600016	pooling specimens	http://purl.obolibrary.org/obo/OBI_0000652	material combination	sample pooling	physical combination of several instances of like material
http://purl.obolibrary.org/obo/OBI_0600018	material portioning	http://purl.obolibrary.org/obo/OBI_0600014	material component separation	apportioning	a material processing in which the input substance is partitioned into a number of portions that are similar in composition.
http://purl.obolibrary.org/obo/OBI_0600020	histological assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	histopathology	An assay that uses visual examination of cells or tissue (or images of them) to make an assessment regarding a quality of the cells or tissue. This assay can include steps of staining, imaging, and judgement.
http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay	http://purl.obolibrary.org/obo/OBI_0003587	cell culture assay	ELISPOT assay	A cytometry assay in which cells are cultured on a surface coated with a capture antibody binding a secretory material of interest which subsequently gets stained resulting in a spot for each cell producing the secretory material of interest.
http://purl.obolibrary.org/obo/OBI_0600037	cell culture splitting	http://purl.obolibrary.org/obo/OBI_0600014	material component separation	cell culture passaging	The act of taking part of a homogeneous cell culture and creating one or more additional separate cultures of similar qualities. input: cell_culture, output cell_culture min cardinality 2. part of cell culturing
http://purl.obolibrary.org/obo/OBI_0600038	addition of molecular label	http://purl.obolibrary.org/obo/OBI_0000094	material processing	labeling	a material processing technique intended to add a molecular label to some input material entity, to allow detection of the molecular target of this label in a detection of molecular label assay
http://purl.obolibrary.org/obo/OBI_0600040	synthesis	http://purl.obolibrary.org/obo/OBI_0000094	material processing	synthesize	the construction of a biomaterial from simpler biomaterials
http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation	http://purl.obolibrary.org/obo/OBI_0000094	material processing	genetic modification	the introduction. alteration or integration of genetic material into a cell or organism
http://purl.obolibrary.org/obo/OBI_0600055	DNA restriction enzyme digestion	http://purl.obolibrary.org/obo/OBI_0600050	specific enzymatic cleavage	restriction enzyme assay	A specific enzymatic cleavage of DNA molecules using endonucleases that cleave DNA molecules at specific sites based on the surrounding nucleotide sequence
http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning	http://purl.obolibrary.org/obo/OBI_0000094	material processing	molecular cloning	a planned process with the objective to insert genetic material into a cloning vector for future replication of the inserted material
http://purl.obolibrary.org/obo/OBI_1000029	phage display library	http://purl.obolibrary.org/obo/OBI_0000731	recombinant vector	display library	a phage display library is a collection of materials in which a mixture of genes or gene fragments is expressed and can be individually selected and amplified.
http://purl.obolibrary.org/obo/OBI_1000036	cell lysate	http://purl.obolibrary.org/obo/OBI_0000047	processed material	lysed material	a cell lysate is a material entity which is output of a cell lysis process
http://purl.obolibrary.org/obo/OBI_1000049	whole mount tissue	http://purl.obolibrary.org/obo/OBI_0000953	processed specimen	whole mount sample	A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide
http://purl.obolibrary.org/obo/OBI_1000207	assay bead	http://purl.obolibrary.org/obo/OBI_0000047	processed material	bead	A globular or round particle of defined physicochemical properties and size which can be exploited as either the primary substance for detection or as a secondary solid platform for the attachment of bioactive molecules.
http://purl.obolibrary.org/obo/OBI_1110010	disposition to cause an allergic reaction	http://purl.obolibrary.org/obo/BFO_0000016	disposition	allergenic disposition	The role borne by a material entity that is realized when it is recognized by the immune system and results in the occurrence of an allergic disease.
http://purl.obolibrary.org/obo/OBI_1110043	cultured adherent cell population	http://purl.obolibrary.org/obo/OBI_0100060	cultured cell population	adherent cell culture sample	A mixed cell population that is characterized by its ability to bind to tissue culture flasks or plates. This population typically contains macrophages and other cells capable of playing the antigen presenting cell role.
http://purl.obolibrary.org/obo/OBI_1110044	cultured PBMC cell population	http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	PBMC cell culture sample	A mixed cell population obtained by processing whole blood. The cells are characterized by having a similar density and are largely mononuclear cells (includes T cells, B cells, and other cell types).
http://purl.obolibrary.org/obo/OBI_1110045	disposition to be bound by an adaptive immune receptor	http://purl.obolibrary.org/obo/BFO_0000016	disposition	epitope disposition	Is the disposition borne by a material entity that is realized in a process of being bound by a adaptive immune receptor.
http://purl.obolibrary.org/obo/OBI_1110047	cultured CD3+ T cell population	http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	CD3+ T cell culture sample	A T cell population characterized by expressing the CD3 molecule on its surface.
http://purl.obolibrary.org/obo/OBI_1110048	cultured CD3- T cell population	http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	CD3- T cell culture sample	A T cell population characterized by not expressing the CD3 molecule on its surface.
http://purl.obolibrary.org/obo/OBI_1110050	cultured CD4- T cell population	http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	CD4- T cell culture sample	A T cell population characterized by not expressing the CD4 molecule on its surface.
http://purl.obolibrary.org/obo/OBI_1110051	cultured CD8- T cell population	http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	CD8- T cell culture sample	A T cell population characterized by not expressing the CD8 molecule on its surface.
http://purl.obolibrary.org/obo/OBI_1110052	cultured CD4-/CD8- T cell population	http://purl.obolibrary.org/obo/OBI_1110051	cultured CD8- T cell population	CD4-/CD8- T cell culture sample	A T cell population characterized by not expressing the CD4 nor the CD8 molecule on its surface.
http://purl.obolibrary.org/obo/OBI_1110085	antigen presentation function	http://purl.obolibrary.org/obo/BFO_0000034	function	APC	a function inhering in a cell  that expresses MHC molecules which is realized in the process of antigen processing and presentation of antigen derived parts by MHC molecules on the cell surface.
http://purl.obolibrary.org/obo/OBI_1110087	donor role	http://purl.obolibrary.org/obo/BFO_0000023	role	donor role	A role which inheres in an organism or part thereof from which any part including cell, organ or tissue is removed with the intention that the donated part will be placed into another organism and/or cultured in vitro.
http://purl.obolibrary.org/obo/OBI_1110092	adjuvant role	http://purl.obolibrary.org/obo/BFO_0000023	role	adjuvent role	Adjuvant role is a role that inheres in a material entity and which is realized through a process of modifying a biological response.
http://purl.obolibrary.org/obo/OBI_1110095	blood specimen collection	http://purl.obolibrary.org/obo/OBI_0600005	collecting specimen from organism	blood harvesting	A specimen collection in which blood is collected from an organism.
http://purl.obolibrary.org/obo/OBI_1110106	cultured antigen presenting cell population	http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	antigen presenting cell culture sample	a cell culture including cells that have an antigen presentation function
http://purl.obolibrary.org/obo/OBI_1110107	cultured effector T cell population	http://purl.obolibrary.org/obo/OBI_0001875	cultured immune cell population	effector T cell culture sample	A cell culture including cells that have an effector T cell function
http://purl.obolibrary.org/obo/OBI_1110132	obsolete CD8 receptor	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	CD8	A transmembrane glycoprotein that serves as a co-receptor for the T cell receptor.
http://purl.obolibrary.org/obo/OBI_1110207	assay detecting IFN-gamma production	http://purl.obolibrary.org/obo/OBI_0000070	assay	IFNg release	An assay that determines information about the production of the cytokine interferon gamma
http://purl.obolibrary.org/obo/PATO_0001632	anterior to	http://purl.obolibrary.org/obo/PATO_0000140	position	frontal	A spatial quality inhering in a bearer by virtue of the bearer's being located toward the front of an organism relative to another entity.
http://purl.obolibrary.org/obo/PR_000023089	DNA ligase	http://purl.obolibrary.org/obo/PR_000000001	protein	ligase	A protein that is a translation product of the Escherichia coli K-12 ligA gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/REO_0000171	obsolete molecular label role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	molecular tracer role	A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay.
http://purl.obolibrary.org/obo/REO_0000280	obsolete molecular label	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class	molecular tracer	A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay
http://purl.obolibrary.org/obo/SO_0000001	region	http://purl.obolibrary.org/obo/BFO_0000031	generically dependent continuant	primary structure of sequence macromolecule	A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids.
http://purl.obolibrary.org/obo/SO_0000104	polypeptide	http://purl.obolibrary.org/obo/SO_0000001	region	polypeptide sequence	A sequence of amino acids linked by peptide bonds which may lack appreciable tertiary structure and may not be liable to irreversible denaturation.
http://purl.obolibrary.org/obo/OBI_0003550	odor baited CDC light trap	http://purl.obolibrary.org/obo/OBI_0002926	Centers for Disease Control and Prevention light trap	human odour baited light trap	A CDC light trap that uses odorous gas from a human being as an attractant, by pumping it from the room where the human being sleeps into the trap.
http://purl.obolibrary.org/obo/OBI_0003551	resting clay pot trap	http://purl.obolibrary.org/obo/OBI_0002939	resting arthropod trap	resting clay pot catch	A resting arthropod trap that consists of a container composed primarily of clay.
http://purl.obolibrary.org/obo/OBI_0003552	proximity ligation-assisted ChIP-seq	http://purl.obolibrary.org/obo/OBI_0002439	chromosome conformation capture assay	PLAC-seq	A chromosome conformation capture assay in which proximity ligation is conducted in nuclei prior to chromatin shearing and immunoprecipitation. Immunopreciptation with an antibody that targets a transcription factor or histone modification allows for selection and enrichment of specific genomic regions for investigation of long-range chromosomal interactions.
http://purl.obolibrary.org/obo/OBI_0004002	non-randomized clinical trial	http://purl.obolibrary.org/obo/OBI_0003699	clinical trial	nonrandomized clinical trial	A clinical trial in which the participants are not assigned by chance to different treatment groups. Participants may choose which group they want to be in, or they may be assigned to the groups by the researchers.
http://purl.obolibrary.org/obo/OBI_0002457	precision nuclear run-on sequencing assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	precision nuclear run-on and sequencing assay	An RNA-seq assay that maps the genome-wide distribution of transcriptionally-engaged Pol II at base-pair resolution by using biotin-labeled ribonucleotide triphosphate analogs (biotin-NTP) for nuclear run-on reactions, allowing the efficient affinity purification of nascent RNAs for high throughput sequencing from their 3' ends.
http://purl.obolibrary.org/obo/OBI_0002458	chromosome conformation capture-on-chip assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	circularized chromosome conformation capture assay	A nuclear ligation assay which uses cross-linking of proteins to proteins and DNA, followed by two rounds of digestion and ligation, inverse PCR, and characterization by microarray or DNA sequencing. This enables unbiased genome-wide screens for DNA contacts made by single genomic sites of interest.
http://purl.obolibrary.org/obo/OBI_0002459	genotype phasing by Hi-C assay	http://purl.obolibrary.org/obo/OBI_0000435	genotyping assay	haplotype reconstruction by Hi-C assay	A genotyping assay in which carbon-copy chromosome conformation is used to detect polymorphism in DNA samples.
http://purl.obolibrary.org/obo/OBI_0002571	polyA-selected RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	mRNA-seq	An RNA-seq assay to study transcriptomes through the enrichment of polyadenylated transcripts or removal of ribosomal RNA prior to high-throughput sequencing.
http://purl.obolibrary.org/obo/OBI_0002572	polyA-depleted RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	polyA-depleted RNA-seq	An RNA-seq assay to study non-polyadenylated transcripts, such as, but not exclusive to unspliced and circular isoforms, through the depletion of polyadenylated transcripts prior to high-throughput sequencing.
http://purl.obolibrary.org/obo/OBI_0002575	isoform sequencing	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	ISO-seq	A method for sequencing isoforms by enriching a cDNA library for full-length reads spanning entire transcript isoforms.
http://purl.obolibrary.org/obo/OBI_0003386	Illumina HiSeq 1500	http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	HiSeq 1500	A DNA sequencer which is manufactured by the Illumina corporation, with a single flow cell. Built upon sequencing by synthesis technology, the machine employs dual surface imaging and offers two high-output options and one rapid-run option.
http://purl.obolibrary.org/obo/OBI_0003391	Affymetrix Mouse Genome 430 2.0 Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	GeneChip Mouse Genome 430 2.0 Array	A DNA microarray manufactured by Affymetrix, which includes complete coverage of the GeneChip Mouse Expression Set 430, for analysis of over 39,000 transcripts and variants from more than 34,000 well-characterized mouse genes and UniGene clusters, on a single array. The sequences for this array were selected from GenBank™, dbEST, and RefSeq., and sequence clusters cretaed from the UniGene database.
http://purl.obolibrary.org/obo/OBI_0003392	Affymetrix Mouse Genome 430A 2.0 Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	GeneChip Mouse Genome 430A 2.0 Array	A DNA microarray manufactured by Affymetrix for gene expression analysis focusing on approximately 14,000 well-characterized genes in the transcribed mouse genome using single-array cartridge. Sequences used in the design of the array were selected from GenBank™, dbEST, and RefSeq. The sequence clusters were created from the UniGene database.
http://purl.obolibrary.org/obo/OBI_0003393	Affymetrix Mouse Gene 1.0 ST Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	GeneChip Mouse Gene 1.0 ST Array	A DNA microarray manufactured by Affymetrix, which is a whole-transcript array that includes probes to measure both messenger (mRNA) and long intergenic non-coding RNA transcripts (lincRNA). This whole-transcript array design provides a complete expression profile of mRNA as well as the intermediary lincRNA transcripts that impact the mRNA expression profile.
http://purl.obolibrary.org/obo/OBI_0003394	Affymetrix Mouse Gene 2.1 ST Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	GeneChip Mouse Gene 2.1 ST Array	A DNA microarray manufactured by Affymetrix, which is a whole-transcript array that includes probes to measure both messenger (mRNA) and long intergenic non-coding RNA transcripts (lincRNA).To supplement the lincRNA data contained in RefSeq, we used sequence and transcript data from lncRNA db.
http://purl.obolibrary.org/obo/OBI_0003395	Affymetrix Rhesus Macaque Genome Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	GeneChip Rhesus Macaque Genome Array	A DNA microarray manufactured by Affymetrix,which is a single-labeled high-density oligonucleotide array, designed to study gene expression in the rhesus animal model and to interrogate rhesus transcripts orthologous to the 3' end of human transcripts. The array consists of over 52,000 probe sets representing more than 20,000 genes, and several relevant viral organisms for studying host-disease immune response.
http://purl.obolibrary.org/obo/OBI_0003396	Affymetrix Human Transcriptome Array 2.0	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	GeneChip Human Transcriptome Array 2.0	A DNA microarray manufactured by Affymetrix, to go beyond gene-level expression profiling to accurately detect all known transcript isoforms produced by a gene. The array design covers >245,000 coding transcripts, >40,000 non-coding transcripts and >339,000 probe sets covering exon-exon junctions, thus ensuring uniform coverage of the transcriptome.
http://purl.obolibrary.org/obo/OBI_0003397	Affymetrix Human Genome U219 Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	Applied Biosystems GeneChip PrimeView Human Gene Expression Array	A DNA microarray manufactured by Affymetrix, which comprises more than 530,000 probes covering more than 36,000 transcripts and variants, which represent more than 20,000 genes mapped through RefSeq or via UniGene annotation. Sequences used in the design of the array were selected from the RefSeq version 36, UniGene database 219, and full-length human mRNAs from GenBank™.
http://purl.obolibrary.org/obo/OBI_0003398	Affymetrix Human Gene 2.0 ST Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray	GeneChip Human Gene 2.0 ST Array	A DNA microarray manufactured by Affymetrix, which provides the most accurate, sensitive, and comprehensive measurement of protein coding (mRNA) and long intergenic non-coding RNA (lincRNA) transcripts. The array design covers >33,500 coding transcripts and >11,000 lincRNA transcripts thus enabling researchers to understand whole-transcriptome gene expression at the gene and exon levels, which allows the study of transcript variants and alternative splicing events.
http://purl.obolibrary.org/obo/OBI_0003415	peripheral blood mononuclear cell specimen	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen	PBMC specimen	A processed specimen that is extracted from whole blood using gradient centrifugation that separates the blood into a layer of peripheral blood mononuclear cells under the top layer of plasma. It contains lymphocytes, monocytes or macrophages that are critical components in the immune system.
http://purl.obolibrary.org/obo/OBI_0003457	epitope protection from infectious challenge experiment based on survival	http://purl.obolibrary.org/obo/OBI_0001179	epitope protection from infectious challenge experiment	survival after infectious challenge	An epitope protection from infectious challenge experiment that determines the success of the epitope intervention based on increased survival of the host compared to controls.
http://purl.obolibrary.org/obo/OBI_0003458	epitope protection from tumor challenge experiment based on burden	http://purl.obolibrary.org/obo/OBI_0001183	epitope protection from tumor challenge experiment	burden after tumor challenge	An epitope protection from tumor challenge experiment in which the readout is a reduction in the presence of malignant cells in the host compared to controls.
http://purl.obolibrary.org/obo/OBI_0003459	epitope protection from tumor challenge experiment based on survival	http://purl.obolibrary.org/obo/OBI_0001183	epitope protection from tumor challenge experiment	survival after tumor challenge	An epitope protection from tumor challenge experiment that determines the success of the epitope intervention based on increased survival of the host compared to controls.
http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity	polymer	A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
http://purl.obolibrary.org/obo/OBI_0003664	Illumina NovaSeq X Plus	http://purl.obolibrary.org/obo/OBI_0003685	Illumina NovaSeq series instrument	NovaSeq X System	A DNA sequencer with three flow cell types manufactured by Illumina. It features a dual-flow cell configuration, allowing to reach an output of up to 16 Tb (52-104 billion reads per run). The sequencer utilizes XLEAP-SBS chemistry, an advanced version of Illumina's sequencing by synthesis (SBS) technology, which enables faster and more accurate sequencing.
http://purl.obolibrary.org/obo/OBI_0002997	arthropod attractor role	http://purl.obolibrary.org/obo/BFO_0000023	role	attractant	A role of a material entity realized in drawing an arthropod in the direction of the material.
http://purl.obolibrary.org/obo/OBI_0003003	landing arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0002904	adult arthropod specimen collection process	collection of landing insects	An arthropod specimen collection process that occurs while the arthropods land on a surface.
http://purl.obolibrary.org/obo/OBI_0003007	arthropod trap containing small non-human animal bait	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap	trap containing small non-human animal bait	An arthropod trap that uses as attractant an animal that is not human and is the size of a chicken or smaller.
http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex	http://purl.obolibrary.org/obo/BFO_0000040	material entity	protein complex	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
http://purl.obolibrary.org/obo/GO_0032640	tumor necrosis factor production	http://purl.obolibrary.org/obo/GO_0071706	tumor necrosis factor superfamily cytokine production	TNF alpha production	The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
http://purl.obolibrary.org/obo/GO_0032641	lymphotoxin A production	http://purl.obolibrary.org/obo/GO_0071706	tumor necrosis factor superfamily cytokine production	TNF beta production	The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.
http://purl.obolibrary.org/obo/GO_0042571	immunoglobulin complex, circulating	http://purl.obolibrary.org/obo/GO_0019814	immunoglobulin complex	antibody	An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.
http://purl.obolibrary.org/obo/OBI_0003589	serum anti-Epstein-Barr virus antibody level assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay	EBV	An antigen specific antibodies assay that is meant to detect antibodies that bind to Epstein-Barr virus (EBV) antigens in a serum sample.
http://purl.obolibrary.org/obo/OBI_0003590	serum anti-cytomegalovirus antibody level assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay	CMV	A CMV antibody assay that has serum as an input.
http://purl.obolibrary.org/obo/OBI_0003591	chronic allograft damage index score	http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item	CADI	A clinical data item that quantifies the degree of tissue damage in biopsies taken from transplanted kidneys.
http://purl.obolibrary.org/obo/OBI_0003592	sequential organ failure assessment score	http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item	SOFA score	A clinical data item that quantifies the degree of function of a critically ill patient's organs.
http://purl.obolibrary.org/obo/OBI_0003593	physician's global assessment of disease activity	http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item	MD global, PGA	A clinical data item that quantifies a physician's judgement of the overall activity of some specific disease in a patient.
http://purl.obolibrary.org/obo/OBI_0003594	human leukocyte antigen mismatch count	http://purl.obolibrary.org/obo/OBI_0001404	genetic characteristics information	HLA mismatch count, HLA mismatch	A genetic characteristics information that is about the number of dissimilarities in the human leukocyte antigen gene complexes of two humans.
http://purl.obolibrary.org/obo/OBI_0003598	single cell B cell receptor repertoire sequencing assay	http://purl.obolibrary.org/obo/OBI_0002991	B cell receptor repertoire sequencing assay	single-cell BCR assay	A B cell receptor repertoire sequencing assay that determines the sequence of DNA or RNA molecules that encode the repertoire of B cell receptors that can be traced to a single cell of origin.
http://purl.obolibrary.org/obo/OBI_0003599	single cell T cell receptor repertoire sequencing assay	http://purl.obolibrary.org/obo/OBI_0002990	T cell receptor repertoire sequencing assay	single-cell TCR assay	A T cell receptor repertoire sequencing assay that determines the sequence of DNA or RNA molecules that encode the repertoire of T cell receptors that can be traced to a single cell of origin.
http://purl.obolibrary.org/obo/OBI_0003601	quartz crystal microbalance assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	QCM	An assay that measures the change in frequency of a quartz crystal resonator resulting from the addition or removal of a small mass of a ligand specifically binding at the surface of the resonator.
http://purl.obolibrary.org/obo/OBI_0003602	quartz crystal microbalance assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0003601	quartz crystal microbalance assay	QCM measuring KD	A quartz crystal microbalance assay that measures the dissociation constant [KD] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0003604	multiplexed error-robust fluorescence in situ hybridization assay	http://purl.obolibrary.org/obo/OBI_0003094	fluorescence in-situ hybridization assay	MERFISH	A fluorescence in-situ hybridization assay that uses combinatorial FISH labeling with error resistant encoding schemes for highly multiplexed single-molecule imaging.
http://purl.obolibrary.org/obo/OBI_0003605	single molecule fluorescence in situ hybridization	http://purl.obolibrary.org/obo/OBI_0003094	fluorescence in-situ hybridization assay	smFISH	A fluorescence in-situ hybridization assay that detects single RNA molecules in fixed cells, allowing for both the quantification and localization at the single-cell level and single-molecule resolution.
http://purl.obolibrary.org/obo/OBI_0003606	Illumina NextSeq 1000	http://purl.obolibrary.org/obo/OBI_0003684	Illumina NextSeq series instrument	NextSeq 1000	A DNA sequencer which is manufactured by the Illumina corporation using sequence-by-synthesis chemistry that fits on a benchtop and uses P1 and P2 flow cells.
http://purl.obolibrary.org/obo/OBI_0003662	single-nucleus methylcytosine and transcriptome sequencing assay	http://purl.obolibrary.org/obo/OBI_0001266	DNA methylation profiling by high throughput sequencing assay	snmCT-seq	A DNA methylation profiling by high throughput sequencing assay that measures the cytosine DNA methylation and gene expression signature of single nuclei.
http://purl.obolibrary.org/obo/OBI_0003667	oral lavage fluid	http://purl.obolibrary.org/obo/OBI_0003666	lavage fluid specimen	mouth rinse specimen	A specimen collected through oral cavity lavage that contains the reagents used to for the lavage process, organisms, cells, cellular secretions, and other biomaterials present in the oral cavity space.
http://purl.obolibrary.org/obo/OBI_0002651	image guided biopsy	http://purl.obolibrary.org/obo/OBI_0002654	needle biopsy	imaging guided biopsy	A biopsy which uses an imaging procedure to guide a needle biopsy.
http://purl.obolibrary.org/obo/OBI_0002652	computed tomography assisted biopsy	http://purl.obolibrary.org/obo/OBI_0002651	image guided biopsy	Computed Tomography-Guided Needle Biopsy	A needle biopsy guided by real-time computed tomography (CT) scan images.
http://purl.obolibrary.org/obo/OBI_0002655	fine needle aspiration biopsy	http://purl.obolibrary.org/obo/OBI_0002654	needle biopsy	FNAB	A biopsy that uses a thin needle to extract cells.
http://purl.obolibrary.org/obo/OBI_0002656	core needle biopsy	http://purl.obolibrary.org/obo/OBI_0002654	needle biopsy	CNB	A biopsy that uses a hollow tube to collect a core of tissue.
http://purl.obolibrary.org/obo/OBI_0002657	surgical biopsy	http://purl.obolibrary.org/obo/OBI_0002650	biopsy	open biopsy	A biopsy involving a surgical incision into an organism to access the biopsy material.
http://purl.obolibrary.org/obo/OBI_0002660	abdominal wall fat pad biopsy	http://purl.obolibrary.org/obo/OBI_0002650	biopsy	fat biopsy	A biopsy involving the collection of a small part of the abdominal wall fat pad.
http://purl.obolibrary.org/obo/OBI_0002661	tail biopsy	http://purl.obolibrary.org/obo/OBI_0002650	biopsy	snip	A biopsy involving the collection of the tip of a mamallian tail.
http://purl.obolibrary.org/obo/OBI_0002663	skinpunch biopsy	http://purl.obolibrary.org/obo/OBI_0002650	biopsy	punch biopsy; skin biopsy	A biopsy that involves the collection of a cylinder of skin (including epidermis, dermis and superficial fat) using a punch tool.
http://purl.obolibrary.org/obo/OBI_0002745	vacuum-assisted biopsy	http://purl.obolibrary.org/obo/OBI_0002654	needle biopsy	VAB	A biopsy performed with a needle augmented with a vacuum device.
http://purl.obolibrary.org/obo/OBI_0002750	Oxford Nanopore MinION	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	ONT MinION, MinION	A portable DNA sequencer which is manufactured by the Oxford Nanopore Technologies corporation, that uses consumable flow cells producing up to 30 Gb of DNA sequence data per flow cell. The sequencer produces real-time results and utilizes nanopore technology with up to 512 nanopore channels in the sensor array.
http://purl.obolibrary.org/obo/OBI_0002751	Oxford Nanopore GridION Mk1	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	Oxford Nanopore GridION X5, GridION Mk1	A DNA sequencer that is manufactured by the Oxford Nanopore Technologies corporation, that can run and analyze up to five individual flow cells producing up to 150 Gb of data per run. The sequencer produces real-time results and utilizes nanopore technology with the option of running the flow cells concurrently or individually.
http://purl.obolibrary.org/obo/OBI_0002752	Oxford Nanopore PromethION	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	PromethION	A DNA sequencer that is manufactured by the Oxford Nanopore Technologies corporation, capable of running up to 48 flow cells and producing up to 7.6 Tb of data per run. The sequencer produces real-time results and utilizes Nanopore technology, with each flow cell allowing up to 3,000 nanopores to be sequencing simultaneously.
http://purl.obolibrary.org/obo/OBI_0002753	PRO-cap	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	PRO-CAP	Precision nuclear run-on and sequencing to detect Pol II initiation sites
http://purl.obolibrary.org/obo/OBI_0002759	ribosomal RNA-depleted RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	rRNA-deleted RNA sequencing assay	An RNA-seq assay in which highly abundant ribosomal RNAs are removed from total RNA before sequencing, resulting in more efficient transcript/gene detection.
http://purl.obolibrary.org/obo/OBI_0002761	lipid profiling assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	lipidomic assay	An analyte assay assay that detects and identifies lipids resulting from biochemical and cellular metabolism.
http://purl.obolibrary.org/obo/OBI_0002762	single-nucleus ATAC-seq	http://purl.obolibrary.org/obo/OBI_0002039	assay for transposase-accessible chromatin using sequencing	snATAC-seq	An ATAC-seq assay in which single nuclei are isolated from frozen tissue samples, through a protocol designed to maximally preserve nucleus integrity during sample processing and optimize transposase-mediated fragmentation of chromatin in individual nuclei.
http://purl.obolibrary.org/obo/OBI_0002763	16s ribosomal gene sequencing assay	http://purl.obolibrary.org/obo/OBI_0002767	amplicon sequencing assay	16S rRNA sequencing assay	An amplicon sequencing assay in which the amplicon is derived from universal primers used to amplify the 16S ribosomal RNA gene from isolate bacterial genomic DNA or metagenomic DNA from a microbioal community. Resulting sequences are compared to reference 16S sequence databases to identify or classify bacteria present within a given sample.
http://purl.obolibrary.org/obo/OBI_0002764	single-cell ATAC-seq	http://purl.obolibrary.org/obo/OBI_0002039	assay for transposase-accessible chromatin using sequencing	scATAC-seq	An ATAC assay designed to robustly map the accessible genome of individual cells, using sequencing integrated into a programmable microfluidics platform, in order to provide insights into cell-to-cell variation in accessibility profiles.
http://purl.obolibrary.org/obo/OBI_0002765	microbiome protein expression profiling assay	http://purl.obolibrary.org/obo/OBI_0000615	protein expression profiling assay	metaproteomic assay	A protein expression profiling assay of microbial proteins extracted from a microbioal community of mixed species from a given microbiome.
http://purl.obolibrary.org/obo/OBI_0002773	single-value binding of antibody with reporter to antigen assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	IA	An assay that detects the linking of antigens and antibodies via special signaling mechanisms, such as EIA, ELISA, chemiluminescence, etc. that produces one measure (quantitative or qualitative) of the analyte of interest
http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model	http://purl.obolibrary.org/obo/OBI_0000658	data representational model	PBPK	A data representation model that predicts the absorption, distribution, metabolism, and excretion (ADME) of chemical substances in biological species based on physiological principles using mathematical modelling technique.
http://purl.obolibrary.org/obo/PBPKO_00004	whole body pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model	All organs PBPK	A physiologically based pharmacokinetic model that contains an explicit representation of the organs most relevant to the ADME of the compound.
http://purl.obolibrary.org/obo/PBPKO_00140	absorption	http://purl.obolibrary.org/obo/GO_0008150	biological process	A	A biological process by which a compound moves from its site of administration into the systemic circulation or a target tissue.
http://purl.obolibrary.org/obo/PBPKO_00144	enterohepatic recirculation	http://purl.obolibrary.org/obo/GO_0008150	biological process	EHR	A biological process involving recycling of compounds through the liver via biliary excretion, intestinal reabsorption, portal circulation return, and re-excretion.
http://purl.obolibrary.org/obo/PBPKO_00219	abcc3	http://purl.obolibrary.org/obo/PBPKO_00217	transporter	ABCC3	A transporter (ATP-binding cassette subfamily C member 3) involved in bile metabolism and transport.
http://purl.obolibrary.org/obo/PBPKO_00220	abcc2	http://purl.obolibrary.org/obo/PBPKO_00217	transporter	ABCC2	A transporter (ATP-binding cassette subfamily C member 2) involved in transporting various molecules across cell membranes.
http://purl.obolibrary.org/obo/PBPKO_00141	absorption rate constant gut	https://github.com/Crispae/pbpko/blob/main/pbpko.owl#OWLClass_6a86eddf_f1dc_4deb_90e9_3d52926078cd	absorption rate constant	Kac gut	An absorption rate constant parameter representing the rate constant for the movement of a compound from the gut to systemic circulation or another compartment.
http://purl.obolibrary.org/obo/PBPKO_00142	absorption rate constant intestine	https://github.com/Crispae/pbpko/blob/main/pbpko.owl#OWLClass_6a86eddf_f1dc_4deb_90e9_3d52926078cd	absorption rate constant	Kac intestine	An absorption rate constant parameter representing the movement of a compound from the intestine to systemic circulation or another compartment.
http://purl.obolibrary.org/obo/PBPKO_00143	gastric emptying rate	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	ge	A biochemical parameter representing the rate at which the stomach empties its contents into the small intestine.
http://purl.obolibrary.org/obo/PBPKO_00147	volume of distribution	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	Vd	A biochemical parameter representing the apparent volume into which a compound distributes in the body relative to its plasma concentration.
http://purl.obolibrary.org/obo/PBPKO_00150	fraction unbound gut	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fugut	An unbound fraction parameter specifically for the gut compartment.
http://purl.obolibrary.org/obo/PBPKO_00151	fraction unbound stomach	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fustomach	An unbound fraction parameter specifically for the stomach compartment.
http://purl.obolibrary.org/obo/PBPKO_00152	fraction unbound intestine	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fuintestine	An unbound fraction parameter specifically for the intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00153	fraction unbound pancreas	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fupancreas	An unbound fraction parameter specifically for the pancreas compartment.
http://purl.obolibrary.org/obo/PBPKO_00154	fraction unbound liver	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fuliver	An unbound fraction parameter specifically for the liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00155	fraction unbound kidney	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fukidney	An unbound fraction parameter specifically for the kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00156	fraction unbound muscle	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fumuscle	An unbound fraction parameter specifically for the muscle compartment.
http://purl.obolibrary.org/obo/PBPKO_00157	fraction unbound heart	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fuheart	An unbound fraction parameter specifically for the heart compartment.
http://purl.obolibrary.org/obo/PBPKO_00158	fraction unbound fat	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fufat	An unbound fraction parameter specifically for the fat (adipose) compartment.
http://purl.obolibrary.org/obo/PBPKO_00159	fraction unbound gonad	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fugonad	An unbound fraction parameter specifically for the gonad compartment.
http://purl.obolibrary.org/obo/PBPKO_00160	fraction unbound skin	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fuskin	An unbound fraction parameter specifically for the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00161	fraction unbound bone	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fubone	An unbound fraction parameter specifically for the bone compartment.
http://purl.obolibrary.org/obo/PBPKO_00162	fraction unbound spleen	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fuspleen	An unbound fraction parameter specifically for the spleen compartment.
http://purl.obolibrary.org/obo/PBPKO_00163	fraction unbound lung	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fulung	An unbound fraction parameter specifically for the lung compartment.
http://purl.obolibrary.org/obo/PBPKO_00164	fraction unbound enterocytes	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fuenterocytes	An unbound fraction parameter specifically within enterocytes.
http://purl.obolibrary.org/obo/PBPKO_00166	gut plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	gut plasma pc	A partition coefficient representing the ratio of compound concentration in gut to plasma.
http://purl.obolibrary.org/obo/PBPKO_00167	stomach plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	stomach plasma pc	A partition coefficient representing the ratio of compound concentration in stomach to plasma.
http://purl.obolibrary.org/obo/PBPKO_00168	intestine plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	intestine plasma pc	A partition coefficient representing the ratio of compound concentration in intestine to plasma.
http://purl.obolibrary.org/obo/PBPKO_00169	pancreas plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	pancreas plasma pc	A partition coefficient representing the ratio of compound concentration in pancreas to plasma.
http://purl.obolibrary.org/obo/PBPKO_00170	liver plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	liver plasma pc	A partition coefficient representing the ratio of compound concentration in liver to plasma.
http://purl.obolibrary.org/obo/PBPKO_00171	kidney plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	kidney plasma pc	A partition coefficient representing the ratio of compound concentration in kidney to plasma.
http://purl.obolibrary.org/obo/PBPKO_00172	muscle plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	muscle plasma pc	A partition coefficient representing the ratio of compound concentration in muscle to plasma.
http://purl.obolibrary.org/obo/PBPKO_00173	heart plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	heart plasma pc	A partition coefficient representing the ratio of compound concentration in heart to plasma.
http://purl.obolibrary.org/obo/PBPKO_00174	fat plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	k_fat_plasma	A partition coefficient representing the ratio of compound concentration in fat (adipose tissue) to plasma.
http://purl.obolibrary.org/obo/PBPKO_00175	gonad plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	gonads plasma pc	A partition coefficient representing the ratio of compound concentration in gonads to plasma.
http://purl.obolibrary.org/obo/PBPKO_00176	skin plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	skin plasma pc	A partition coefficient representing the ratio of compound concentration in skin to plasma.
http://purl.obolibrary.org/obo/PBPKO_00177	bone plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	k_bone_plasma	A partition coefficient representing the ratio of compound concentration in bone to plasma.
http://purl.obolibrary.org/obo/PBPKO_00178	spleen plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	spleen plasma pc	A partition coefficient representing the ratio of compound concentration in spleen to plasma.
http://purl.obolibrary.org/obo/PBPKO_00179	lung plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	lung plasma pc	A partition coefficient representing the ratio of compound concentration in lung to plasma.
http://purl.obolibrary.org/obo/PBPKO_00180	rich perfused plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	rich perfused plasma pc	A partition coefficient representing the ratio of compound concentration in the lumped richly perfused compartment to plasma.
http://purl.obolibrary.org/obo/PBPKO_00181	poor perfused plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	poor perfused plasma pc	A partition coefficient representing the ratio of compound concentration in the lumped poorly perfused compartment to plasma.
http://purl.obolibrary.org/obo/PBPKO_00182	skin stratum corneum partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	skin sc pc	A partition coefficient representing the ratio of compound concentration in the stratum corneum to the rest of the skin.
http://purl.obolibrary.org/obo/PBPKO_00183	air plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	air plasma pc	A partition coefficient representing the ratio of compound concentration in air to plasma.
http://purl.obolibrary.org/obo/PBPKO_00187	blood:plasma ratio	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	bp	A biochemical parameter representing the ratio of compound concentration in whole blood to that in plasma.
http://purl.obolibrary.org/obo/PBPKO_00189	catalytic rate constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	kcat	A biochemical parameter quantifying enzymatic reaction velocity (kcat), representing the maximum number of substrate molecules converted per active site per unit time.
http://purl.obolibrary.org/obo/PBPKO_00211	maximum rate in intestine	http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	vmax intestine	A maximum rate (Vmax) of an enzyme catalysed reaction for a compound in the intestine when the enzyme is saturated with substrate.
http://purl.obolibrary.org/obo/PBPKO_00212	Michaelis constant  intestine	http://biomodels.net/SBO/SBO_0000027	Michaelis constant	km intestine	Michaelis constant representing the substrate concentration at which the reaction rate in the intestine is half of Vmax (Km).
http://purl.obolibrary.org/obo/PBPKO_00213	maximum rate in liver	http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	vmax liver	A maximum rate (Vmax) of an enzyme catalysed reaction for a compound in the liver when the enzyme is saturated with substrate.
http://purl.obolibrary.org/obo/PBPKO_00214	Michaelis constant  liver	http://biomodels.net/SBO/SBO_0000027	Michaelis constant	km liver	Michaelis constant representing the substrate concentration at which the reaction rate in the liver is half of Vmax (Km).
http://purl.obolibrary.org/obo/PBPKO_00216	dissociation constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	kd	A biochemical parameter (Kd) measuring the affinity of a compound for its binding partner (e.g., receptor, protein).
http://purl.obolibrary.org/obo/PBPKO_00221	degradation rate constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	kdeg	A biochemical parameter (kdeg) representing the rate constant for the degradation of a metabolizing enzyme or transporter.
http://purl.obolibrary.org/obo/PBPKO_00222	inhibition constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	ki	A biochemical parameter (Ki) representing the inhibition constant for a specific enzyme or transporter interaction.
http://purl.obolibrary.org/obo/PBPKO_00235	intrinsic clearance rate	http://purl.obolibrary.org/obo/PBPKO_00229	clearance rate	clint	A clearance rate representing the inherent ability of an organ or tissue to eliminate a compound, independent of blood flow or binding.
http://purl.obolibrary.org/obo/PBPKO_00304	maximum rate of basolateral transporter in vitro	http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	vmax baso in vitro	Maximum rate (Vmax) of transport via a basolateral transporter, measured in vitro.
http://purl.obolibrary.org/obo/PBPKO_00305	Michaelis constant baso	http://biomodels.net/SBO/SBO_0000027	Michaelis constant	km baso	Michaelis constant representing the substrate concentration at half-maximal velocity (Km) for a basolateral transporter.
http://purl.obolibrary.org/obo/PBPKO_00306	maximum rate of apical transporter in vitro	http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	vmax apical in vitro	A maximum rate (Vmax) of an enzyme catalysed reaction for a compound across the apical membrane of an organ, measured in vitro, when the enzyme is saturated with substrate.
http://purl.obolibrary.org/obo/PBPKO_00307	Michaelis constant apical	http://biomodels.net/SBO/SBO_0000027	Michaelis constant	km apical	Michaelis constant representing the substrate concentration at half-maximal velocity (Km) for an apical transporter.
http://purl.obolibrary.org/obo/PBPKO_00310	influx constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	kiff	A biochemical parameter (kin) describing the rate constant for compound movement into a cell or compartment.
http://purl.obolibrary.org/obo/PBPKO_00311	efflux rate constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	keffluxc	A biochemical parameter (kefflux) describing the rate constant for compound movement out of a cell or compartment.
http://purl.obolibrary.org/obo/PBPKO_00315	effective permeability	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	peff	A biochemical parameter (Peff) representing the rate at which a compound passes through a biological barrier (e.g., intestinal wall).
http://purl.obolibrary.org/obo/PBPKO_00363	hippocampus brain partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	hippocampus brain pc	A partition coefficient representing the ratio of compound concentration in the hippocampus to the overall brain.
http://purl.obolibrary.org/obo/PBPKO_00364	cerebrum brain partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	cerebrum brain pc	A partition coefficient representing the ratio of compound concentration in the cerebrum to the overall brain.
http://purl.obolibrary.org/obo/PBPKO_00365	cerebellum brain partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	cerebellum brain pc	A partition coefficient representing the ratio of compound concentration in the cerebellum to the overall brain.
http://purl.obolibrary.org/obo/PBPKO_00366	frontalcortex brain partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	frontalcortex brain pc	A partition coefficient representing the ratio of compound concentration in the frontal cortex to the overall brain.
http://purl.obolibrary.org/obo/PBPKO_00367	apparent permeability cerebrum to rest of brain	http://purl.obolibrary.org/obo/PBPKO_00612	apparent permeability	papp cerebrum brain	Apparent permeability of a compound specifically between the cerebrum and the rest of the brain.
http://purl.obolibrary.org/obo/PBPKO_00368	apparent permeability cerebellum to rest of brain	http://purl.obolibrary.org/obo/PBPKO_00612	apparent permeability	papp cerebellum brain	Apparent permeability of a compound specifically between the cerebellum and the rest of the brain.
http://purl.obolibrary.org/obo/PBPKO_00369	apparent permeability hippocampus to rest of brain	http://purl.obolibrary.org/obo/PBPKO_00612	apparent permeability	papp hippocampus brain	Apparent permeability of a compound specifically between the hippocampus and the rest of the brain.
http://purl.obolibrary.org/obo/PBPKO_00370	apparent permeability cortex to rest of brain	http://purl.obolibrary.org/obo/PBPKO_00612	apparent permeability	papp cortex brain	Apparent permeability of a compound specifically between the cortex and the rest of the brain.
http://purl.obolibrary.org/obo/PBPKO_00389	maximum rate in fetus	http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	vmax fetus	A maximum rate (Vmax) of an enzyme catalysed reaction for a compound in fetus when the enzyme is saturated with substrate.
http://purl.obolibrary.org/obo/PBPKO_00390	amniotic transfer coefficient	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	atc	A biochemical parameter representing the rate at which a compound transfers from maternal circulation to amniotic fluid.
http://purl.obolibrary.org/obo/PBPKO_00391	liverfetus plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	liverfetus plasma pc	A partition coefficient representing the ratio of compound concentration in the fetal liver to plasma.
http://purl.obolibrary.org/obo/PBPKO_00392	brainfetus plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	brainfetus plasma pc	A partition coefficient representing the ratio of compound concentration in the fetal brain to plasma.
http://purl.obolibrary.org/obo/PBPKO_00393	kidneyfetus plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	kidneyfetus plasma pc	A partition coefficient representing the ratio of compound concentration in the fetal kidney to plasma.
http://purl.obolibrary.org/obo/PBPKO_00394	restbodyfetus plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	restbody plasma pc	A partition coefficient representing the ratio of compound concentration in the fetal rest of body compartment to plasma.
http://purl.obolibrary.org/obo/PBPKO_00432	particle density	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	ps	A biochemical/physical parameter representing the mass per unit volume of particles (e.g., of the administered compound).
http://purl.obolibrary.org/obo/PBPKO_00434	intestinal transit time	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	itt	A biochemical parameter representing the time required for a compound to move through the intestine.
http://purl.obolibrary.org/obo/PBPKO_00437	fraction unbound milk	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fumilk	An unbound fraction parameter specifically for milk.
http://purl.obolibrary.org/obo/PBPKO_00442	milk plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	milk plasma pc	A partition coefficient representing the ratio of compound concentration in milk to plasma.
http://purl.obolibrary.org/obo/PBPKO_00515	brain plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	brain plasma pc	A partition coefficient representing the ratio of compound concentration in the brain to plasma.
http://purl.obolibrary.org/obo/PBPKO_00517	mammary gland plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	mam plasma pc	A partition coefficient representing the ratio of compound concentration in the mammary gland to plasma.
http://purl.obolibrary.org/obo/PBPKO_00518	restbody plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	restbody plasma pc	A partition coefficient representing the ratio of compound concentration in the rest of body compartment to plasma.
http://purl.obolibrary.org/obo/PBPKO_00519	tissue plasma partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	kt	A partition coefficient representing the ratio of compound concentration in a generic tissue to plasma.
http://purl.obolibrary.org/obo/PBPKO_00520	urinary rate constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	kurine c	A biochemical parameter (rate constant) representing the rate at which a compound is cleared via urine, often scaled by body weight.
http://purl.obolibrary.org/obo/PBPKO_00534	urinary rate	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	kurine	A biochemical parameter representing the rate at which a compound is cleared via urine.
http://purl.obolibrary.org/obo/PBPKO_00535	resorption maximum	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	tmc	A biochemical parameter (Tm) representing the maximum rate of tubular resorption (e.g., in the kidney).
http://purl.obolibrary.org/obo/PBPKO_00536	resorption	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	tm	A biochemical parameter or process representing the resorption of a compound (e.g., tubular resorption).
http://purl.obolibrary.org/obo/PBPKO_00537	octanol air partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	koa	A partition coefficient (Koa) representing the ratio of compound concentration in octanol to air at equilibrium.
https://github.com/Crispae/pbpko/blob/main/pbpko.owl#OWLClass_6a86eddf_f1dc_4deb_90e9_3d52926078cd	absorption rate constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	ka	A biochemical parameter representing the rate constant at which a compound is absorbed into systemic circulation or a target compartment from the site of administration
http://purl.obolibrary.org/obo/PBPKO_00127	molecular weight	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	MW	A physicochemical parameter representing the sum of the weights of all atoms in a molecule.
http://purl.obolibrary.org/obo/PBPKO_00129	distribution coefficient	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	Log D	A physicochemical parameter representing the logarithm of the ratio of concentrations of a compound in a mixture of two immiscible phases at equilibrium, specifically describing lipophilicity (LogD).
http://purl.obolibrary.org/obo/PBPKO_00131	logarithmic solubility	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	log S	A physicochemical parameter representing the 10-based logarithm of a compound's solubility (typically in mol/L).
http://purl.obolibrary.org/obo/PBPKO_00133	acid dissociation constant	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	pka	A physicochemical parameter representing the negative base-10 logarithm (pKa) of the acid dissociation constant (Ka).
http://purl.obolibrary.org/obo/PBPKO_00134	basic dissociation constant	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	pKb pK(b) pK(B) affinity constant, Base dissociation constant	A physicochemical parameter representing the negative base-10 logarithm (pKb) of the base dissociation constant (Kb).
http://purl.obolibrary.org/obo/PBPKO_00136	hydrogen acceptor count	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	A	A physicochemical parameter representing the integer number of hydrogen bond acceptors in a molecular entity.
http://purl.obolibrary.org/obo/PBPKO_00431	diffusion coefficient	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	D	A physicochemical parameter representing the amount of substance diffusing across a unit area per unit time under a unit concentration gradient.
http://purl.obolibrary.org/obo/PBPKO_00007	body mass index	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	BMI	A physiological parameter calculated as an individual's weight (kg) divided by the square of their height (m).
http://purl.obolibrary.org/obo/PBPKO_00008	bodyweight	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	bw	A physiological parameter representing the mass or quantity of heaviness of an individual.
http://purl.obolibrary.org/obo/PBPKO_00009	height	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	ht	A physiological parameter describing the distance from the bottom to the top of someone standing upright.
http://purl.obolibrary.org/obo/PBPKO_00010	surface area	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	BSA/SA	A physiological parameter representing the total area that the surface of an object occupies.
http://purl.obolibrary.org/obo/PBPKO_00013	cardiac output rate	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	CO	A blood flow rate parameter representing the volume of blood pumped by the heart compartment per unit of time.
http://purl.obolibrary.org/obo/PBPKO_00014	blood flow rate to stomach	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qstomach	A blood flow rate parameter specifically describing the rate to the stomach compartment.
http://purl.obolibrary.org/obo/PBPKO_00015	fraction of blood flow to stomach	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqstomach	The dimensionless fraction of cardiac output delivered to the stomach compartment.
http://purl.obolibrary.org/obo/PBPKO_00016	blood flow rate to intestine	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qintestine	A blood flow parameter specifically describing the rate to the intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00017	fraction of blood flow to intestine	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqintestine	The dimensionless fraction of cardiac output delivered to the intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00018	blood flow rate to small intestine	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qsmall intestine	A blood flow rate parameter specifically describing the rate to the small intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00019	fraction of blood flow to small intestine	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqsmallintestine	The dimensionless fraction of cardiac output delivered to the small intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00020	blood flow rate to large intestine	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qlargeintestine	A blood flow rate parameter specifically describing the rate to the large intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00021	fraction of blood flow to large intestine	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqlargeinestine	The dimensionless fraction of cardiac output delivered to the large intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00022	blood flow rate to pancreas	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qpancreas	A blood flow rate parameter specifically describing the rate to the pancreas compartment.
http://purl.obolibrary.org/obo/PBPKO_00023	fraction of blood flow to pancreas	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqpancreas	The dimensionless fraction of cardiac output delivered to the pancreas compartment.
http://purl.obolibrary.org/obo/PBPKO_00024	blood flow rate to liver	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qliver	A blood flow rate parameter specifically describing the rate to the liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00025	fraction of blood flow to liver	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqliver	The dimensionless fraction of cardiac output delivered to the liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00026	blood flow rate to kidney	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qkidney	A blood flow rate parameter specifically describing the rate to the kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00027	fraction of blood flow to kidney	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqkidney	The dimensionless fraction of cardiac output delivered to the kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00028	blood flow rate to muscle	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qmuscle	A blood flow rate parameter specifically describing the rate to the muscle compartment.
http://purl.obolibrary.org/obo/PBPKO_00029	fraction of blood flow to muscle	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqmuscle	The dimensionless fraction of cardiac output delivered to the muscle compartment.
http://purl.obolibrary.org/obo/PBPKO_00030	blood flow rate to heart	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qheart	A blood flow rate parameter specifically describing the rate to the heart compartment.
http://purl.obolibrary.org/obo/PBPKO_00031	fraction of blood flow to heart	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqheart	The dimensionless fraction of cardiac output delivered to the heart compartment.
http://purl.obolibrary.org/obo/PBPKO_00032	blood flow rate to fat	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qfat	A blood flow rate parameter specifically describing the rate to the fat (adipose tissue) compartment.
http://purl.obolibrary.org/obo/PBPKO_00033	fraction of blood flow to fat	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqfat	The dimensionless fraction of cardiac output delivered to the fat compartment.
http://purl.obolibrary.org/obo/PBPKO_00034	blood flow rate to gonad	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qgonad	A blood flow parameter specifically describing the rate to the gonads compartment.
http://purl.obolibrary.org/obo/PBPKO_00035	fraction of blood flow to gonad	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqgonad	The dimensionless fraction of cardiac output delivered to the gonad compartment.
http://purl.obolibrary.org/obo/PBPKO_00036	blood flow rate to skin	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qskin	A blood flow rate parameter specifically describing the rate to the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00037	fraction of blood flow to skin	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqskin	The dimensionless fraction of cardiac output delivered to the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00038	blood flow rate to bone	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qbone	A blood flow rate parameter specifically describing the rate to the bone compartment.
http://purl.obolibrary.org/obo/PBPKO_00039	fraction of blood flow to bone	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqbone	The dimensionless fraction of cardiac output delivered to the bone compartment.
http://purl.obolibrary.org/obo/PBPKO_00040	blood flow rate to brain	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qbrain	A blood flow rate parameter specifically describing the rate to the brain compartment.
http://purl.obolibrary.org/obo/PBPKO_00041	fraction of blood flow to brain	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqbrain	The dimensionless fraction of cardiac output delivered to the brain compartment.
http://purl.obolibrary.org/obo/PBPKO_00042	blood flow rate to spleen	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qspleen	A blood flow rate parameter specifically describing the rate to the spleen compartment.
http://purl.obolibrary.org/obo/PBPKO_00043	fraction of blood flow to spleen	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqspleen	The dimensionless fraction of cardiac output delivered to the spleen compartment.
http://purl.obolibrary.org/obo/PBPKO_00044	blood flow rate to lung	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qlung	A blood flow rate parameter specifically describing the rate to the lung compartment.
http://purl.obolibrary.org/obo/PBPKO_00045	fraction of blood flow to lung	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqlung	The dimensionless fraction of cardiac output delivered to the lung compartment.
http://purl.obolibrary.org/obo/PBPKO_00046	blood flow rate to poorly perfused	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qpoorlyperfused	A blood flow rate parameter specifically describing the rate to the poorly perfused organ/tissue compartment.
http://purl.obolibrary.org/obo/PBPKO_00047	fraction of blood flow to poorly perfused	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqpoorlyperfused	The dimensionless fraction of cardiac output delivered to the poorly perfused compartment.
http://purl.obolibrary.org/obo/PBPKO_00048	blood flow rate to richly perfused	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qrichlyperfused	A blood flow rate parameter specifically describing the rate to the richly perfused organ/tissue compartment.
http://purl.obolibrary.org/obo/PBPKO_00049	fraction of blood flow to richly perfused	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqrichlyperfused	The dimensionless fraction of cardiac output delivered to the richly perfused compartment.
http://purl.obolibrary.org/obo/PBPKO_00050	blood flow rate to restbody	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qrestbody	A blood flow rate parameter specifically describing the rate to the rest of body compartment (total minus specified organs).
http://purl.obolibrary.org/obo/PBPKO_00051	fraction of blood flow to restbody	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqrestbody	The dimensionless fraction of cardiac output delivered to the rest of the body compartment.
http://purl.obolibrary.org/obo/PBPKO_00052	blood flow rate to gall bladder	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qgallbladder	A blood flow rate parameter specifically describing the rate to the gall bladder compartment.
http://purl.obolibrary.org/obo/PBPKO_00053	fraction of blood flow to gall bladder	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqgallbladder	The dimensionless fraction of cardiac output delivered to the gall bladder compartment.
http://purl.obolibrary.org/obo/PBPKO_00054	blood flow rate to portal vein	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qportalvein	A blood flow rate parameter specifically describing the rate to the portal vein compartment.
http://purl.obolibrary.org/obo/PBPKO_00055	fraction of blood flow to portal vein	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqportalvein	The dimensionless fraction of cardiac output delivered to the portal vein compartment.
http://purl.obolibrary.org/obo/PBPKO_00056	blood flow rate to lymph	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qlymph	A blood flow rate parameter specifically describing the rate to the lymph compartment.
http://purl.obolibrary.org/obo/PBPKO_00057	fraction of blood flow to lymph	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqlymph	The dimensionless fraction of cardiac output delivered to the lymph compartment.
http://purl.obolibrary.org/obo/PBPKO_00058	amount of metabolized	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	ametab	An output parameter representing the total amount of compound metabolized.
http://purl.obolibrary.org/obo/PBPKO_00060	fraction of blood flow to stratum corneum	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	scfblood	The dimensionless fraction of cardiac output delivered to the stratum corneum compartment.
http://purl.obolibrary.org/obo/PBPKO_00061	fraction of exposed skin	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fskin e	A dimensionless fraction of volume defined as the exposed skin volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00062	fraction of unexposed skin	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fskin u	A dimensionless fraction of volume defined as the unexposed skin volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00065	glomerular filtration rate	http://purl.obolibrary.org/obo/PBPKO_00636	bodily fluid flow rate parameter	gfr	A bodily fluid flow rate parameter (or physiological process measure) describing the flow rate of filtered fluid through the kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00067	volume of stomach	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vstomach	A volume parameter representing the total volume of the stomach compartment.
http://purl.obolibrary.org/obo/PBPKO_00068	fraction of stomach	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fstomach	A dimensionless fraction of volume defined as the stomach volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00069	volume of intestine	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vintestine	A volume parameter representing the total volume of the intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00070	fraction of intestine	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fintestine	A dimensionless fraction of volume defined as the intestine volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00071	volume of small intestine	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vsmall intestine	A volume parameter representing the total volume of the small intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00072	fraction of small intestine	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fsmall intestine	A dimensionless fraction of volume defined as the small intestine volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00073	volume of large intestine	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vlarge intestine	A volume parameter representing the total volume of the large intestine compartment.
http://purl.obolibrary.org/obo/PBPKO_00074	fraction of large intestine	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	flarge intestine	A dimensionless fraction of volume defined as the large intestine volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00075	volume of pancreas	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vpancreas	A volume parameter representing the total volume of the pancreas compartment.
http://purl.obolibrary.org/obo/PBPKO_00076	fraction of pancreas	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fpancreas	A dimensionless fraction of volume defined as the pancreas volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00077	volume of liver	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vliver	A volume parameter representing the total volume of the liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00078	fraction of liver	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fliver	A dimensionless fraction of volume defined as the liver volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00079	volume of kidney	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vkidney	A volume parameter representing the total volume of the kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00080	fraction of kidney	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fkidney	A dimensionless fraction of volume defined as the kidney volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00081	volume of muscle	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vmuscle	A volume parameter representing the total volume of muscle compartment.
http://purl.obolibrary.org/obo/PBPKO_00082	fraction of muscle	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fmuscle	A dimensionless fraction of volume defined as the muscle volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00083	volume of heart	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vheart	A volume parameter representing the total volume of the heart compartment.
http://purl.obolibrary.org/obo/PBPKO_00084	fraction of heart	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fheart	A dimensionless fraction of volume defined as the heart volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00085	volume of fat	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vfat	A volume parameter representing the total volume of fat (adipose tissue) compartment.
http://purl.obolibrary.org/obo/PBPKO_00086	fraction of fat	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	ffat	A dimensionless fraction of volume defined as the fat volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00087	volume of gonad	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vgonad	A volume parameter representing the total volume of the gonad compartment.
http://purl.obolibrary.org/obo/PBPKO_00088	fraction of gonad	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fgonad	A dimensionless fraction of volume defined as the gonad volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00089	volume of skin	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vskin	A volume parameter representing the total volume of the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00090	fraction of skin	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fskin	A dimensionless fraction of volume defined as the skin volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00091	volume of bone	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vbone	A volume parameter representing the total volume of bone compartment.
http://purl.obolibrary.org/obo/PBPKO_00092	fraction of bone	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fbone	A dimensionless fraction of volume defined as the bone volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00093	volume of brain	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vbrain	A volume parameter representing the total volume of the brain compartment.
http://purl.obolibrary.org/obo/PBPKO_00094	fraction of brain	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fbrain	A dimensionless fraction of volume defined as the brain volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00095	volume of spleen	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vspleen	A volume parameter representing the total volume of the spleen compartment.
http://purl.obolibrary.org/obo/PBPKO_00096	fraction of spleen	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fspleen	A dimensionless fraction of volume defined as the spleen volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00097	volume of lung	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vlung	A volume parameter representing the total volume of the lung compartment.
http://purl.obolibrary.org/obo/PBPKO_00098	fraction of lung	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	flung	A dimensionless fraction of volume defined as the lung volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00099	volume of poorly perfused	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vpoorly perfused	A volume parameter representing the total volume of the poorly perfused compartment.
http://purl.obolibrary.org/obo/PBPKO_00100	fraction of poorly perfused	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fpoorly perfused	A dimensionless fraction of volume defined as the poorly perfused compartment volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00101	volume of richly perfused	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vrichly perfused	A volume parameter representing the total volume of the richly perfused compartment.
http://purl.obolibrary.org/obo/PBPKO_00102	fraction of richly perfused	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	frichly perfused	A dimensionless fraction of volume defined as the richly perfused compartment volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00103	volume of plasma	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vplasma	A volume parameter representing the total volume of plasma compartment.
http://purl.obolibrary.org/obo/PBPKO_00104	fraction of plasma	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fplasma	A dimensionless fraction of volume defined as the plasma volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00105	volume of rest body	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vrest body	A volume parameter representing the total volume of the rest of body compartment.
http://purl.obolibrary.org/obo/PBPKO_00106	fraction of rest body	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	frest body	A dimensionless fraction of volume defined as the rest of body volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00107	volume of stratum corneum with respect to blood	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	scvblood	A volume parameter representing the total volume of stratum corneum compartment with respect to blood/plasma.
http://purl.obolibrary.org/obo/PBPKO_00108	volume of blood	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vblood	A volume parameter representing the total volume of blood compartment.
http://purl.obolibrary.org/obo/PBPKO_00109	volume of exposed skin	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vskin e	A volume parameter representing the total volume of the exposed skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00111	volume of unexposed skin	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vskin u	A volume parameter representing the total volume of the unexposed skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00112	volume of stratum corneum exposed	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vskin sc e	A volume parameter representing the total volume of the exposed stratum corneum compartment.
http://purl.obolibrary.org/obo/PBPKO_00113	volume of unexposed stratum corneum	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vskin sc u	A volume parameter representing the total volume of the unexposed stratum corneum compartment.
http://purl.obolibrary.org/obo/PBPKO_00114	fraction alveolar volume	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	falv	A dimensionless fraction of volume defined as the alveolar volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00115	volume of gall bladder	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vgall bladder	A volume parameter representing the total volume of the gall bladder compartment.
http://purl.obolibrary.org/obo/PBPKO_00116	fraction of gall bladder	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fgall bladder	A dimensionless fraction of volume defined as the gall bladder volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00117	volume of portal vein	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vportal vein	A volume parameter representing the total volume of the portal vein compartment.
http://purl.obolibrary.org/obo/PBPKO_00118	fraction of portal vein	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fportal vein	A dimensionless fraction of volume defined as the portal vein volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00119	volume of lymph	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vlymph	A volume parameter representing the total volume of lymph compartment.
http://purl.obolibrary.org/obo/PBPKO_00120	fraction of lymph	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	flymph	A dimensionless fraction of volume defined as the lymph volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00334	infant lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage	Inf	A lifestage parameter representing a very young child, typically under one year of age.
http://purl.obolibrary.org/obo/PBPKO_00335	toddler lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage	Tdl	A lifestage parameter representing a young child, typically between one and three years old.
http://purl.obolibrary.org/obo/PBPKO_00348	cerebrospinal fluid volume	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	spinal csf volume	A volume parameter representing the total volume of cerebrospinal fluid (CSF) compartment in the spinal region.
http://purl.obolibrary.org/obo/PBPKO_00349	cranial cerebrospinal fluid volume	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	cranial csf volume	A volume parameter representing the total volume of cerebrospinal fluid (CSF) compartment in the cranial region.
http://purl.obolibrary.org/obo/PBPKO_00352	spinal cerebrospinal fluid flow rate	http://purl.obolibrary.org/obo/PBPKO_00636	bodily fluid flow rate parameter	spinal csf flow	A bodily fluid flow rate parameter representing the flow rate of cerebrospinal fluid (CSF) compartment in the spinal region.
http://purl.obolibrary.org/obo/PBPKO_00355	volume of hippocampus	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vhippocampus	A volume parameter representing the total volume of the hippocampus compartment.
http://purl.obolibrary.org/obo/PBPKO_00356	volume of frontal cortex	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vfrontal cortex	A volume parameter representing the total volume of the frontal cortex compartment.
http://purl.obolibrary.org/obo/PBPKO_00357	volume of cerebrum	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vcerebrum	A volume parameter representing the total volume of the cerebrum compartment.
http://purl.obolibrary.org/obo/PBPKO_00358	volume of cerebellum	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vcerebellum	A volume parameter representing the total volume of the cerebellum compartment.
http://purl.obolibrary.org/obo/PBPKO_00359	blood flow rate to hippocampus	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qhippocampus	A blood flow rate parameter specifically describing the rate to the hippocampus compartment.
http://purl.obolibrary.org/obo/PBPKO_00360	blood flow rate to frontal cortex	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qfrontalcortex	A blood flow rate parameter specifically describing the rate to the frontal cortex compartment.
http://purl.obolibrary.org/obo/PBPKO_00361	blood flow rate to cerebrum	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qcerebrum	A blood flow rate parameter specifically describing the rate to the cerebrum compartment.
http://purl.obolibrary.org/obo/PBPKO_00362	blood flow rate to cerebellum	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qcerebellum	A blood flow rate parameter specifically describing the rate to the cerebellum compartment.
http://purl.obolibrary.org/obo/PBPKO_00373	volume of fetus	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vfetus	A volume parameter representing the total volume of the fetus.
http://purl.obolibrary.org/obo/PBPKO_00374	volume of placenta	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vplacenta	A volume parameter representing the total volume of the placental compartment.
http://purl.obolibrary.org/obo/PBPKO_00375	volume of amniotic fluid	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vaf	A volume parameter representing the total volume of the amniotic fluid compartment.
http://purl.obolibrary.org/obo/PBPKO_00376	volume of liver fetus	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vliver fetus	A volume parameter representing the total volume of the fetal liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00377	volume of brain fetus	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vbrainfetus	A volume parameter representing the total volume of the fetal brain compartment.
http://purl.obolibrary.org/obo/PBPKO_00378	volume of kidney fetus	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vkidneyfetus	A volume parameter representing the total volume of the fetal kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00379	volume of rest body fetus	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vrest body fetus	A volume parameter representing the total volume of the rest of body compartment within the fetus.
http://purl.obolibrary.org/obo/PBPKO_00382	fetal cardiac output rate	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	fco	A blood flow rate parameter representing the volume of blood pumped by the fetal heart compartment per unit time.
http://purl.obolibrary.org/obo/PBPKO_00383	blood flow rate to liverfetus	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qliverfetus	A blood flow rate parameter specifically describing the rate to the fetal liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00384	blood flow rate to kidneyfetus	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qkidneyfetus	A blood flow rate parameter specifically describing the rate to the fetal kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00385	blood flow rate to brain fetus	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qbrainfetus	A blood flow rate parameter specifically describing the rate to the fetal brain compartment.
http://purl.obolibrary.org/obo/PBPKO_00386	blood flow rate to restbody fetus	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qrestbodyfetus	A blood flow rate parameter specifically describing the rate to the rest of body compartment within the fetus.
http://purl.obolibrary.org/obo/PBPKO_00387	gestational age	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	ga	A physiological parameter representing the age of a pregnancy, typically measured in weeks.
http://purl.obolibrary.org/obo/PBPKO_00388	gestational week	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	gw	A physiological parameter representing the specific week of gestation.
http://purl.obolibrary.org/obo/PBPKO_00409	fraction of blood flow to duodenum	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqduodenum	The dimensionless fraction of cardiac output delivered to the duodenum compartment.
http://purl.obolibrary.org/obo/PBPKO_00410	fraction of blood flow to jejunum	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqjejunum	The dimensionless fraction of cardiac output delivered to the jejunum compartment.
http://purl.obolibrary.org/obo/PBPKO_00411	fraction of blood flow to ileum	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqileum	The dimensionless fraction of cardiac output delivered to the ileum compartment.
http://purl.obolibrary.org/obo/PBPKO_00412	fraction of blood flow to colon	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqcolon	The dimensionless fraction of cardiac output delivered to the colon compartment.
http://purl.obolibrary.org/obo/PBPKO_00413	fraction of blood flow to cecum	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqcecum	The dimensionless fraction of cardiac output delivered to the cecum compartment.
http://purl.obolibrary.org/obo/PBPKO_00414	blood flow rate to duodenum	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qduodenum	A blood flow rate parameter specifically describing the rate to the duodenum compartment.
http://purl.obolibrary.org/obo/PBPKO_00415	blood flow rate to jejunum	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qjejunum	A blood flow rate parameter specifically describing the rate to the jejunum compartment.
http://purl.obolibrary.org/obo/PBPKO_00416	blood flow rate to ileum	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qileum	A blood flow rate parameter specifically describing the rate to the ileum compartment.
http://purl.obolibrary.org/obo/PBPKO_00417	blood flow rate to colon	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qcolon	A blood flow rate parameter specifically describing the rate to the colon compartment.
http://purl.obolibrary.org/obo/PBPKO_00418	blood flow rate to cecum	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qcecum	A blood flow rate parameter specifically describing the rate to the cecum compartment.
http://purl.obolibrary.org/obo/PBPKO_00419	fraction of duodenum	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fduodenum	A dimensionless fraction of volume defined as the duodenum volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00420	fraction of jejunum	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fjejunum	A dimensionless fraction of volume defined as the jejunum volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00421	fraction of ileum	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fileum	A dimensionless fraction of volume defined as the ileum volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00422	fraction of colon	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fcolon	A dimensionless fraction of volume defined as the colon volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00423	fraction of cecum	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fcecum	A dimensionless fraction of volume defined as the cecum volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00424	volume of duodenum	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vduodenum	A volume parameter representing the total volume of the duodenum compartment.
http://purl.obolibrary.org/obo/PBPKO_00425	volume of jejunum	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vjejunum	A volume parameter representing the total volume of the jejunum compartment.
http://purl.obolibrary.org/obo/PBPKO_00426	volume of ileum	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vileum	A volume parameter representing the total volume of the ileum compartment.
http://purl.obolibrary.org/obo/PBPKO_00427	volume of colon	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vcolon	A volume parameter representing the total volume of the colon compartment.
http://purl.obolibrary.org/obo/PBPKO_00428	volume of cecum	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vcecum	A volume parameter representing the total volume of the cecum compartment.
http://purl.obolibrary.org/obo/PBPKO_00508	fraction of filtrate	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	ffiltrate	A dimensionless fraction of volume defined as the filtrate volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00509	fraction of gut	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fgut	A dimensionless fraction of volume defined as the gut volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00510	fraction of mammary gland	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fmam	A dimensionless fraction of volume defined as the mammary gland volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00511	fraction of blood flow to filtrate	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqfiltrate	The dimensionless fraction of cardiac output delivered to the filtrate compartment.
http://purl.obolibrary.org/obo/PBPKO_00512	fraction of blood flow to bone marrow	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqbm	The dimensionless fraction of cardiac output delivered to the bone marrow compartment.
http://purl.obolibrary.org/obo/PBPKO_00513	fraction of blood flow to gut	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqgut	The dimensionless fraction of cardiac output delivered to the gut compartment.
http://purl.obolibrary.org/obo/PBPKO_00514	fraction of blood flow to mammary gland	http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	fqmam	The dimensionless fraction of cardiac output delivered to the mammary gland compartment.
http://purl.obolibrary.org/obo/PBPKO_00522	volume of filtrate	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vfiltrate	A volume parameter representing the total volume of the filtrate compartment.
http://purl.obolibrary.org/obo/PBPKO_00523	volume of bone marrow	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vbm	A volume parameter representing the total volume of the bone marrow compartment.
http://purl.obolibrary.org/obo/PBPKO_00524	volume of gut	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vgut	A volume parameter representing the total volume of the gut compartment.
http://purl.obolibrary.org/obo/PBPKO_00525	volume of mammary gland	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vmam	A volume parameter representing the total volume of the mammary gland compartment.
http://purl.obolibrary.org/obo/PBPKO_00526	volume of mass balance	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vmass bal	A volume parameter representing the check for total mass balance of all compartments (sum of organ volumes should equal body volume/weight equivalent, depending on units).
http://purl.obolibrary.org/obo/PBPKO_00527	hematocrit volume	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	vhct	A volume parameter representing the total volume of red blood cells in whole blood.
http://purl.obolibrary.org/obo/PBPKO_00528	cardiac output rate of plasma	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qcplasma	A blood flow rate parameter representing the cardiac output specifically related to plasma flow.
http://purl.obolibrary.org/obo/PBPKO_00529	blood flow rate to filtrate	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qfiltrate	A blood flow rate parameter specifically describing the rate to the filtrate compartment (representing glomerular filtration).
http://purl.obolibrary.org/obo/PBPKO_00530	blood flow rate to bone marrow	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qbm	A blood flow parameter specifically describing the rate to the bone marrow compartment.
http://purl.obolibrary.org/obo/PBPKO_00531	blood flow rate to gut	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qgut	A blood flow rate parameter specifically describing the rate to the gut compartment.
http://purl.obolibrary.org/obo/PBPKO_00532	blood flow rate to mammary gland	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qmam	A blood flow rate parameter specifically describing the rate to the mammary gland compartment.
http://purl.obolibrary.org/obo/PBPKO_00533	blood flow rate for mass balance	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	qmassbal	A blood flow rate parameter representing the check for total blood flow mass balance of all the compartments (sum of organ flows should equal cardiac output).
http://purl.obolibrary.org/obo/PBPKO_00243	intravenous bolus exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure	IVB	A route of exposure involving rapid injection directly into a vein.
http://purl.obolibrary.org/obo/PBPKO_00244	intravenous infusion exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure	IVI	A route of exposure involving continuous administration directly into a vein over time.
http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment	http://purl.obolibrary.org/obo/PBPKO_00636	bodily fluid flow rate parameter	Q	A bodily fluid flow rate parameter representing the rate of blood flow in different parts of the body
http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	Vorgan	A physiological parameter representing the volume of a specific organ or tissue.
http://purl.obolibrary.org/obo/PBPKO_00110	fraction of surface area exposed	http://purl.obolibrary.org/obo/PBPKO_00010	surface area	fsa exposed	A surface area parameter representing the fraction of skin surface area actually exposed.
http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	FU	A biochemical parameter representing the fraction of a compound that is not bound (e.g., to proteins).
http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	Kp	A biochemical parameter representing the ratio of the concentration of a compound in a particular tissue to its concentration in plasma/blood at equilibrium.
http://purl.obolibrary.org/obo/PBPKO_00184	skin diffusion coefficient	http://purl.obolibrary.org/obo/PBPKO_00431	diffusion coefficient	kp sc	A diffusion coefficient representing the diffusion of a compound across the skin.
http://purl.obolibrary.org/obo/PBPKO_00185	human serum albumin	http://purl.obolibrary.org/obo/BFO_0000040	material entity	HSA	A material entity representing distribution-related protein (most abundant in human plasma) that binds various compounds.
http://purl.obolibrary.org/obo/PBPKO_00229	clearance rate	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	cl	A biochemical parameter representing the volume of biological fluid cleared of a compound per unit time.
http://purl.obolibrary.org/obo/PBPKO_00253	peak concentration	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	Cmax	An output parameter representing the highest concentration (Cmax) of a compound achieved after exposure.
http://purl.obolibrary.org/obo/PBPKO_00254	maximum steady state concentration	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	cmaxss	An output parameter representing the maximum concentration (Cmax,ss) achieved at steady state during repeated dosing.
http://purl.obolibrary.org/obo/PBPKO_00255	maximum time	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	tmax	An output parameter representing the time (Tmax) required to reach the peak concentration.
http://purl.obolibrary.org/obo/PBPKO_00256	area under curve	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	AUC	An output parameter representing the integral of the concentration-time curve (AUC), indicating total exposure.
http://purl.obolibrary.org/obo/PBPKO_00257	area under curve 0 to t	http://purl.obolibrary.org/obo/PBPKO_00256	area under curve	auc 0 to t	An area under curve parameter calculated from time zero to a specific time point t (AUC0-t).
http://purl.obolibrary.org/obo/PBPKO_00258	area under curve last	http://purl.obolibrary.org/obo/PBPKO_00256	area under curve	auclast	An area under curve parameter calculated from time zero to the time of the last measurable concentration (AUClast).
http://purl.obolibrary.org/obo/PBPKO_00259	area under curve 0 to infinity	http://purl.obolibrary.org/obo/PBPKO_00256	area under curve	auc 0 infinity	An area under curve parameter extrapolated from time zero to infinity (AUC0-inf), representing total exposure after a single dose.
http://purl.obolibrary.org/obo/PBPKO_00260	area under moment curve	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	aumc	An output parameter calculated as the integral of the product of time and concentration versus time (AUMC).
http://purl.obolibrary.org/obo/PBPKO_00261	mean residence time	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	MRT	An output parameter representing the average time a compound resides in the body (MRT).
http://purl.obolibrary.org/obo/PBPKO_00262	half-life	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	t1/2	An output parameter representing the time required for the compound concentration to decrease by half (t1/2).
http://purl.obolibrary.org/obo/PBPKO_00263	bioavailability	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	f	An output parameter representing the rate and extent to which an active compound is absorbed and becomes available at the site of action or systemic circulation.
http://purl.obolibrary.org/obo/PBPKO_00264	relative bioavailability	http://purl.obolibrary.org/obo/PBPKO_00263	bioavailability	frel	A bioavailability parameter comparing the rate and extent of absorption of a test compound to a reference compound.
http://purl.obolibrary.org/obo/PBPKO_00265	mean absorption time	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	MAT	An output parameter representing the average time for a compound to be absorbed into systemic circulation (MAT).
http://purl.obolibrary.org/obo/PBPKO_00266	mean dissolution time	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	MDT	An output parameter representing the average time for a compound to dissolve in the body (MDT).
http://purl.obolibrary.org/obo/PBPKO_00267	bioequivalence	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	be	An output parameter indicating comparable bioavailability between test and reference formulations under similar conditions.
http://purl.obolibrary.org/obo/PBPKO_00268	absolute bioavailability	http://purl.obolibrary.org/obo/PBPKO_00263	bioavailability	fabs	A bioavailability parameter comparing the amount reaching systemic circulation after non-IV administration to the amount available after IV administration.
http://purl.obolibrary.org/obo/PBPKO_00272	amount in urine	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	aurine	The amount of compound in the urine compartment.
http://purl.obolibrary.org/obo/PBPKO_00273	amount in feces	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	afeces	The amount of compound in the feces compartment.
http://purl.obolibrary.org/obo/PBPKO_00277	steady state area under curve	http://purl.obolibrary.org/obo/PBPKO_00256	area under curve	aucss	An area under curve parameter calculated over a dosing interval at steady state (AUCss).
http://purl.obolibrary.org/obo/PBPKO_00549	concentration in plasma	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cplasma	The total concentration of compound in the plasma compartment.
http://purl.obolibrary.org/obo/PBPKO_00284	tolerable daily intake	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	tdi	An output parameter (or exposure limit) estimating the amount of a substance that can be ingested daily over a lifetime without appreciable health risk (TDI).
http://purl.obolibrary.org/obo/PBPKO_00286	estimated daily intake	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	edi	An output parameter estimating the amount of a compound consumed daily (EDI).
http://purl.obolibrary.org/obo/PBPKO_00287	biomonitoring equivalent	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	be	An output parameter representing the concentration of a chemical (or metabolite) in a biological medium consistent with exposure guidance values (BE).
http://purl.obolibrary.org/obo/PBPKO_00289	reference dose	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	RfD	An output parameter (or exposure limit) estimating the daily oral or dermal exposure likely to be without appreciable risk over a lifetime (RfD).
http://purl.obolibrary.org/obo/PBPKO_00290	acceptable daily intake	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	adi	An output parameter (or exposure limit) estimating the amount of a substance in food/water that can be consumed daily without appreciable health risk (ADI).
http://purl.obolibrary.org/obo/PBPKO_00298	concentration in hair	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	chair	The total concentration of compound in the hair compartment.
http://purl.obolibrary.org/obo/PBPKO_00299	concentration in nail	http://purl.obolibrary.org/obo/PBPKO_00297	biological matrix concentration	cnail	A biological matrix concentration specifically representing the total concentration of compound in the nail compartment.
http://purl.obolibrary.org/obo/PBPKO_00300	concentration in teeth	http://purl.obolibrary.org/obo/PBPKO_00297	biological matrix concentration	cteeth	A biological matrix concentration specifically representing the total concentration of compound in the teeth compartment.
http://purl.obolibrary.org/obo/PBPKO_00301	concentration in blood	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cblood	The total concentration of compound in the blood compartment.
http://purl.obolibrary.org/obo/PBPKO_00302	concentration in urine	http://purl.obolibrary.org/obo/PBPKO_00297	biological matrix concentration	curine	A biological matrix concentration specifically representing the total concentration of compound in the urine compartment.
http://purl.obolibrary.org/obo/PBPKO_00351	blood brain barrier compartment	http://purl.obolibrary.org/obo/PBPKO_00495	barrier compartment	bbb cpt	A barrier compartment representing the blood-brain barrier (BBB).
http://purl.obolibrary.org/obo/PBPKO_00354	blood cerebrospinal fluid compartment	http://purl.obolibrary.org/obo/PBPKO_00495	barrier compartment	bc csf compartment	A barrier compartment representing the blood-cerebrospinal fluid barrier (BCSFB).
http://purl.obolibrary.org/obo/OBI_0002543	atrial appendage specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from the atrium auricular region.
http://purl.obolibrary.org/obo/OBI_0002550	sigmoid colon specimen	http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen		A specimen that is derived from sigmoid colon.
http://purl.obolibrary.org/obo/OBI_0002466	alignment counting algorithm	http://purl.obolibrary.org/obo/IAO_0000064	algorithm		An algorithm used to assign aligned sequence reads, resulting from a reference genome transcriptome alignment algorithm, to sequence features (e.g. genes or transcripts).
http://purl.obolibrary.org/obo/OBI_0002467	alignment counting application	http://purl.obolibrary.org/obo/IAO_0000594	software application		A software application that implements an alignment counting algorithm, used to count the overlap of aligned sequencing reads with genes.
http://purl.obolibrary.org/obo/OBI_0002468	base calling algorithm	http://purl.obolibrary.org/obo/IAO_0000064	algorithm		An algorithm that assigns nucleotides to temporal or spatial peaks generated by a detector, such as peaks of light intensities generated by a DNA sequencer
http://purl.obolibrary.org/obo/OBI_0002469	base calling application	http://purl.obolibrary.org/obo/IAO_0000594	software application		A base-calling application that implments a base-calling algorithm to convert BCL (binary base call) files, (e.g., those generated by Illumina sequencing systems) to standard FASTQ file formats for downstream analysis.
http://purl.obolibrary.org/obo/OBI_0002461	BCL format	http://purl.obolibrary.org/obo/IAO_0000098	data format specification		A data format specification that is a binary file containing base calling data. These files are created by sequencing machines during the act of sequencing, and contain data about each of the nucleotide clusters on a sequencing flow cell.
http://purl.obolibrary.org/obo/OBI_0002470	bcl2fastq software application	http://purl.obolibrary.org/obo/OBI_0002469	base calling application		A base calling application that implments a base calling algorithm to convert BCL (binary base call) files generated by Illumina sequencing systems to standard FASTQ file formats for downstream analysis.
http://purl.obolibrary.org/obo/OBI_0002471	date process started	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the date when a process was initiated.
http://purl.obolibrary.org/obo/OBI_0002462	ERCC RNA spike-in	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A processed material developed by the External RNA Controls Consortium (ERCC) that  consists of 92 transcripts, derived and traceable from NIST-certified DNA plasmids.
http://purl.obolibrary.org/obo/OBI_0002473	material amplification role	http://purl.obolibrary.org/obo/OBI_0000116	worker role		A worker role played by the person who runs the enzymatic amplifying process.
http://purl.obolibrary.org/obo/OBI_0002474	material sequencing library preparation role	http://purl.obolibrary.org/obo/OBI_0000116	worker role		A worker role played by the person who performs the library preparation process to generate a sequencing library for a sample to be sequenced.
http://purl.obolibrary.org/obo/OBI_0002487	microraft	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A material separation device also commerically known as Isoraft, that is used to isolate single cells.
http://purl.obolibrary.org/obo/OBI_0002476	number of rounds of amplification	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the number of times an amplification reaction happened.
http://purl.obolibrary.org/obo/OBI_0002488	pipette	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is a laboratory tool commonly used in chemistry, biology and medicine to transport a measured volume of liquid, often as a media dispenser.
http://purl.obolibrary.org/obo/OBI_0002477	reference genome role	http://purl.obolibrary.org/obo/OBI_0000025	reference substance role		A reference substance role that is played by a reference genome when used during sequence alignment.
http://purl.obolibrary.org/obo/OBI_0002478	reference genome-transcriptome alignment algorithm	http://purl.obolibrary.org/obo/IAO_0000064	algorithm		An algorithm that attempts to align a nucleic acid sequence to a reference genome and transcriptome.
http://purl.obolibrary.org/obo/OBI_0002481	single-end library	http://purl.obolibrary.org/obo/OBI_0002754	cDNA library		A cDNA library that is a collection of short tags from only one end of DNA fragments.
http://purl.obolibrary.org/obo/OBI_0002463	SIRV RNA spike-in	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A processed material that consists of transcript isoforms of 7 spike-in RNA variant (SIRV) genes and possibly the 92 External RNA Controls Consortium (ERCC) RNA spike-in genes.
http://purl.obolibrary.org/obo/OBI_0002483	spike-in dilution factor	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that indicates the dilution of spike-in added to a specimen.
http://purl.obolibrary.org/obo/OBI_0002484	star algorithm	http://purl.obolibrary.org/obo/OBI_0002478	reference genome-transcriptome alignment algorithm		A reference genome transcriptome alignment algorithm that is a standalone RNA-seq alignment algorithm that uses uncompressed suffix arrays and a mapping algorithm similar to those used in large-scale genome alignment tools to align RNA-seq reads to a genomic reference.
http://purl.obolibrary.org/obo/OBI_0002486	verse algorithm	http://purl.obolibrary.org/obo/OBI_0002466	alignment counting algorithm		An alignment counting algorithm that assigns gene features to genomic alignments using a hierarchical assignment scheme, which allows simultaneous quantification of multiple feature types or annotation levels without repeatedly assigning reads.
http://purl.obolibrary.org/obo/OBI_0003112	Olink assay	http://purl.obolibrary.org/obo/OBI_0003113	proximity extension assay		A proximity extension assay that uses quantitative polymerase chain reaction (qPCR) technology to determine the concentration/presence of proteins using a high-multiplex, high-throughput protein biomarker platform. The assay utilizes two distinct oligonucleotide-labeled antibodies (‘probes’) that bind at different sites for each detected protein. When the two probes are in close proximity, a new PCR target sequence is formed by a proximity-dependent DNA polymerization event. The resulting sequence is subsequently detected and quantified using standard real-time PCR.
http://purl.obolibrary.org/obo/OBI_0003232	cerebrospinal fluid assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has a cerebrospinal fluid specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003233	endotracheal aspirate assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has an endotracheal aspirate specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003234	induced sputum assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has an induced sputum specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003235	lung assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has a lung specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003236	milk assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has a milk specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003237	feces assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has a feces specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003238	umbilical cord blood assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that has an umbilical cord blood specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003239	saliva assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has a saliva specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003240	cerebrospinal fluid microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a cerebrospinal fluid specimen.
http://purl.obolibrary.org/obo/OBI_0003241	endotracheal tube aspirate microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in an endotracheal aspirate specimen.
http://purl.obolibrary.org/obo/OBI_0003242	induced sputum microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in an induced sputum specimen.
http://purl.obolibrary.org/obo/OBI_0003243	blood assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of a blood assay.
http://purl.obolibrary.org/obo/OBI_0003244	blood microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a blood microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003245	feces assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of a feces assay.
http://purl.obolibrary.org/obo/OBI_0003246	feces microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a feces microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003247	urine assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of a urine assay.
http://purl.obolibrary.org/obo/OBI_0003248	urine microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a urine microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003249	induced sputum assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of a induced sputum assay.
http://purl.obolibrary.org/obo/OBI_0003251	induced sputum microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of an induced sputum microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003252	cerebrospinal fluid assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of a cerebrospinal fluid assay.
http://purl.obolibrary.org/obo/OBI_0003253	cerebrospinal fluid microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a cerebrospinal fluid microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003254	endotracheal aspirate assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		An organism detection datum that is the specified output of an endotracheal aspirate assay.
http://purl.obolibrary.org/obo/OBI_0003255	endotracheal tube aspirate microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of an endotracheal tube aspirate microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003256	lung microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a lung microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003257	nasopharyngeal or oropharyngeal swab microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a nasopharyngeal or oropharyngeal swab microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003258	pleural fluid microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a pleural fluid microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003259	umbilical cord blood assay datum	http://purl.obolibrary.org/obo/OBI_0003243	blood assay datum		A data item that is the specified output of an umbilical cord blood assay.
http://purl.obolibrary.org/obo/OBI_0003260	umbilical cord blood microbiology datum	http://purl.obolibrary.org/obo/OBI_0003259	umbilical cord blood assay datum		An organism detection datum that is the specified output of an umbilical cord blood microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003261	bacteria in blood datum	http://purl.obolibrary.org/obo/OBI_0003244	blood microbiology datum		A blood microbiology datum that is about bacteria.
http://purl.obolibrary.org/obo/OBI_0003262	virus in blood datum	http://purl.obolibrary.org/obo/OBI_0003244	blood microbiology datum		A blood microbiology datum that is about a virus.
http://purl.obolibrary.org/obo/OBI_0003263	eukaryota in blood datum	http://purl.obolibrary.org/obo/OBI_0003244	blood microbiology datum		A blood microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003264	bacteria in feces datum	http://purl.obolibrary.org/obo/OBI_0003246	feces microbiology datum		A feces microbiology datum that is about bacteria.
http://purl.obolibrary.org/obo/OBI_0003265	eukaryota in feces datum	http://purl.obolibrary.org/obo/OBI_0003246	feces microbiology datum		A feces microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003266	virus in feces datum	http://purl.obolibrary.org/obo/OBI_0003246	feces microbiology datum		A feces microbiology datum that is about a virus.
http://purl.obolibrary.org/obo/OBI_0003267	eukaryota in urine datum	http://purl.obolibrary.org/obo/OBI_0003248	urine microbiology datum		A urine microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003268	bacteria in induced sputum datum	http://purl.obolibrary.org/obo/OBI_0003251	induced sputum microbiology datum		An induced sputum microbiology datum that is about bacteria.
http://purl.obolibrary.org/obo/OBI_0003269	eukaryota in induced sputum datum	http://purl.obolibrary.org/obo/OBI_0003251	induced sputum microbiology datum		An induced sputum microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003270	virus in induced sputum datum	http://purl.obolibrary.org/obo/OBI_0003251	induced sputum microbiology datum		An induced sputum microbiology datum that is about a virus.
http://purl.obolibrary.org/obo/OBI_0003271	bacteria in endotracheal tube aspirate datum	http://purl.obolibrary.org/obo/OBI_0003255	endotracheal tube aspirate microbiology datum		An endotracheal tube aspirate microbiology datum that is about bacteria.
http://purl.obolibrary.org/obo/OBI_0003272	bacteria in lung datum	http://purl.obolibrary.org/obo/OBI_0003256	lung microbiology datum		A lung microbiology datum that is about bacteria.
http://purl.obolibrary.org/obo/OBI_0003273	eukaryota in lung datum	http://purl.obolibrary.org/obo/OBI_0003256	lung microbiology datum		A lung microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003274	virus in lung datum	http://purl.obolibrary.org/obo/OBI_0003256	lung microbiology datum		A lung microbiology datum that is about a virus.
http://purl.obolibrary.org/obo/OBI_0003275	bacteria in nasopharyngeal or oropharyngeal swab datum	http://purl.obolibrary.org/obo/OBI_0003257	nasopharyngeal or oropharyngeal swab microbiology datum		A nasopharyngeal or oropharyngeal swab microbiology datum that is about bacteria.
http://purl.obolibrary.org/obo/OBI_0003283	pleural fluid microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a pleural fluid specimen.
http://purl.obolibrary.org/obo/OBI_0003284	umbilical cord blood microbiology assay	http://purl.obolibrary.org/obo/OBI_0002649	blood microbiology assay		An organism detection assay that detects microorganisms in an umbilical cord blood specimen.
http://purl.obolibrary.org/obo/OBI_0003285	nasopharyngeal or oropharyngeal swab microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a nasopharyngeal or oropharyngeal swab specimen.
http://purl.obolibrary.org/obo/OBI_0003608	disease severity reduction objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification that is fulfilled by reducing the severity of a disease in a particular organism.
http://purl.obolibrary.org/obo/OBI_0003660	in vitro CRISPR screen using single-cell RNA-seq	http://purl.obolibrary.org/obo/OBI_0003659	in vitro CRISPR screen assay		An in vitro CRISPR screen assay that uses single-cell RNA-Seq to detect induced changes in gene expression.
http://purl.obolibrary.org/obo/PATO_0103000	quantitative	http://purl.obolibrary.org/obo/PATO_0000001	quality		A quality of an entity that can be represented numerically, including anything that can be counted, measured, or given a numerical value.
http://purl.obolibrary.org/obo/OBI_0003712	assay of organismal behavior	http://purl.obolibrary.org/obo/OBI_0002441	physical examination of an organism		A physical examination to assess behavior quality in a live organism.
http://purl.obolibrary.org/obo/OBI_0003716	blood pressure assay	http://purl.obolibrary.org/obo/OBI_0003715	vital sign assay		A vital sign assay that determines the blood pressure (force of blood against the artery walls) of an organism.
http://purl.obolibrary.org/obo/CHEBI_39867	valproic acid	http://purl.obolibrary.org/obo/CHEBI_35366	fatty acid		A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
http://purl.obolibrary.org/obo/CHEBI_16526	carbon dioxide	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A one-carbon compound with formula CO2 in which the carbon is attached to each oxygen atom by a double bond. A colourless, odourless gas under normal conditions, it is produced during respiration by all animals, fungi and microorganisms that depend directly or indirectly on living or decaying plants for food.
http://purl.obolibrary.org/obo/CHEBI_17347	testosterone	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5..
http://purl.obolibrary.org/obo/CHEBI_17855	triglyceride	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Any glyceride resulting from the condensation of all three hydroxy groups of glycerol (propane-1,2,3-triol) with fatty acids.
http://purl.obolibrary.org/obo/CHEBI_17996	chloride	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A halide anion formed when chlorine picks up an electron to form an an anion.
http://purl.obolibrary.org/obo/CHEBI_31624	fluorescein (lactone form)	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		A xanthene dye that is highly fluorescent, detectable even when present in minute quantities. Used forensically to detect traces of blood, in analytical chemistry as an indicator in silver nitrate titrations and in microscopy.
http://purl.obolibrary.org/obo/CHEBI_6495	lipoprotein	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		A clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
http://purl.obolibrary.org/obo/CHEBI_22868	bile salt	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A sodium salt of the conjugate of any bile acid with either glycine or taurine.
http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity	http://purl.obolibrary.org/obo/BFO_0000040	material entity		Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity.
http://purl.obolibrary.org/obo/CHEBI_23995	N-ethyl-N-nitrosourea	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
http://purl.obolibrary.org/obo/CHEBI_24636	proton	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Nuclear particle of charge number +1, spin 1/2 and rest mass of 1.007276470(12) u.
http://purl.obolibrary.org/obo/CHEBI_2637	amikacin	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group.
http://purl.obolibrary.org/obo/CHEBI_26710	sodium chloride	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An inorganic chloride salt having sodium(1+) as the counterion.
http://purl.obolibrary.org/obo/CHEBI_28619	acrylamide	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A member of the class of acrylamides that results from the formal condensation of acrylic acid with ammonia.
http://purl.obolibrary.org/obo/CHEBI_28864	tobramycin	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring.
http://purl.obolibrary.org/obo/CHEBI_29101	sodium(1+)	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A monoatomic monocation obtained from sodium.
http://purl.obolibrary.org/obo/CHEBI_29103	potassium(1+)	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A monoatomic monocation obtained from potassium.
http://purl.obolibrary.org/obo/CHEBI_32875	methyl group	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An alkyl group that is the univalent group derived from methane by removal of a hydrogen atom.
http://purl.obolibrary.org/obo/CHEBI_33250	atom	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A chemical entity constituting the smallest component of an element having the chemical properties of the element.
http://purl.obolibrary.org/obo/CHEBI_37445	folic acids	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid units.
http://purl.obolibrary.org/obo/CHEBI_37972	phosphorus-32 atom	http://purl.obolibrary.org/obo/OBI_0001879	reagent		The radioactive isotope of phosphorus with relative atomic mass 31.973907 and half-life of 14.26 days.
http://purl.obolibrary.org/obo/CHEBI_37973	phosphorus-33 atom	http://purl.obolibrary.org/obo/OBI_0001879	reagent		The radioactive isotope of phosphorus with relative atomic mass 32.971725, half-life of 25.34 days and nuclear spin (1)/2.
http://purl.obolibrary.org/obo/CHEBI_39025	high-density lipoprotein	http://purl.obolibrary.org/obo/CHEBI_6495	lipoprotein		A class of lipoproteins of small size (4-13 nm) and dense (greater than 1.063 g/ml) particles. They are synthesized in the liver without a lipid core, accumulate cholesterol esters from peripheral tissues and transport them to the liver for re-utilization or elimination from the body (the reverse cholesterol transport).
http://purl.obolibrary.org/obo/CHEBI_39026	low-density lipoprotein	http://purl.obolibrary.org/obo/CHEBI_6495	lipoprotein		A class of lipoproteins of small size (18-25 nm) and low density (1.019-1.063 g/ml) particles with a core composed mainly of cholesterol esters and smaller amounts of triglycerides. The surface monolayer consists mostly of phospholipids, a single copy of apolipoprotein B-100, and free cholesterol molecules. The main function of LDL is to transport cholesterol and cholesterol esters from the liver. Excessive levels are associated with cardiovascular disease.
http://purl.obolibrary.org/obo/CHEBI_39027	very-low-density lipoprotein	http://purl.obolibrary.org/obo/CHEBI_6495	lipoprotein		A class of lipoproteins of large size (30-80 nm), very low density (0.93-1.006 g/ml) particles with a core composed mainly of triglycerides and a surface monolayer of phospholipids and cholesterol into which are imbedded the apolipoproteins B, E, and C. VLDL facilitate the transport of endogenously made triglycerides to extrahepatic tissues.
http://purl.obolibrary.org/obo/CHEBI_42098	digoxigenin	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		A hydroxy steroid that consists of 5beta-cardanolide having a double bond at the 20(22)-position as well as hydroxy groups at the 3beta-, 12beta- and 14beta-positions. It has been isolated from the plant species of the genus Digitalis.
http://purl.obolibrary.org/obo/CHEBI_47774	low-density lipoprotein cholesterol	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Cholesterol esters and free cholesterol which are contained in or bound to low-density lipoproteins (LDL).
http://purl.obolibrary.org/obo/CHEBI_47775	high-density lipoprotein cholesterol	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Cholesterol esters and free cholesterol which are contained in or bound to high-density lipoproteins (HDL).
http://purl.obolibrary.org/obo/CHEBI_59050	dimethyl sulfate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		The dimethyl ester of sulfuric acid.
http://purl.obolibrary.org/obo/CHEBI_9754	tris	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC.
http://purl.obolibrary.org/obo/CHEBI_50076	chromium-51	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A synthetic radioactive isotope of chromium having a half-life of 27.7 days and decaying by electron capture with emission of gamma rays (0.32 MeV); it is used to label red blood cells for measurement of mass or volume, survival time, and sequestration studies, for the diagnosis of gastrointestinal bleeding, and to label platelets to study their survival.
http://purl.obolibrary.org/obo/CHEBI_61057	tacrolimus hydrate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A hydrate that is the monohydrate form of tacrolimus.
http://purl.obolibrary.org/obo/PR_000016261	serotransferrin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human TF gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000016801	transthyretin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human TTR gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/OBI_0002140	temperature measurement assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay to determine the temperature of an evaluant.
http://purl.obolibrary.org/obo/OBI_0002566	file merge	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation in which data contained in 2 or more files are merged into a single file.
http://purl.obolibrary.org/obo/OBI_0002567	sequence alignment	http://purl.obolibrary.org/obo/OBI_0200187	sequence analysis data transformation		A data transformation in which one or more sequences (reads) are positioned on a reference sequence template (often a reference set of genes), according to the genetic base-pairing paradigm.
http://purl.obolibrary.org/obo/OBI_0002568	sequence data feature count tabulation	http://purl.obolibrary.org/obo/OBI_0200187	sequence analysis data transformation		The counting of features (typically, genes) within aligned sequence data, and organization of these counts into one or more tables.
http://purl.obolibrary.org/obo/OBI_0002569	trimmed sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		The results of a data transformation of sequence data in which (e.g., low quality) read bases are removed, to achieve some specific objective.
http://purl.obolibrary.org/obo/OBI_0002578	adapter sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		Nucleotide sequences of molecules that are ligated to assay samples prior to sequencing of these samples;  these sequences are provided by assay kit manufacturers and typically used to combine sequencing of multiple samples in one assay run.
http://purl.obolibrary.org/obo/OBI_0002579	adapter-trimmed sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		The results of a data transformation of sequence data in which reference subsequences corresponding to ligated library adapters are removed.
http://purl.obolibrary.org/obo/OBI_0002580	aligned sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		The results of a sequence alignment.
http://purl.obolibrary.org/obo/OBI_0002581	merged aligned sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		The results of a data transformation of sequence data in which files containing aligned sequence data are merged together
http://purl.obolibrary.org/obo/OBI_0002582	sequence library feature count data	http://purl.obolibrary.org/obo/IAO_0000100	data set		The results of a sequence data feature count tabulation.
http://purl.obolibrary.org/obo/OBI_0002583	DNA methylation profiling data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		The results of a DNA methylation profiling assay
http://purl.obolibrary.org/obo/OBI_0002584	differential expression analysis data	http://purl.obolibrary.org/obo/IAO_0000100	data set		The results of a differential expression analysis.
http://purl.obolibrary.org/obo/OBI_0002585	sequence trimming	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation in which subsequences of a molecular sequence are cut (removed).
http://purl.obolibrary.org/obo/OBI_0002587	machine learning	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to give a computer the ability to use patterns in data to progressively improve its performance on a specific task, achieved by using statistical techniques instead of explicitly programming the ability.
http://purl.obolibrary.org/obo/OBI_0002588	supervised machine learning	http://purl.obolibrary.org/obo/OBI_0002587	machine learning		A machine learning process using a function that maps an input to an output based on example input-output pairs. It infers a function from labeled training data consisting of a set of training examples.
http://purl.obolibrary.org/obo/OBI_0003229	plasma proteomics assay	http://purl.obolibrary.org/obo/OBI_0001318	proteomic profiling by array assay		A proteomics profiling assay that detects proteins in a blood plasma specimen.
http://purl.obolibrary.org/obo/GO_0140730	amphiregulin production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of amphiregulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.
http://purl.obolibrary.org/obo/OBI_0003365	milk assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of a milk assay.
http://purl.obolibrary.org/obo/UBERON_0000310	breast	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The upper ventral region of the torso of an organism.
http://purl.obolibrary.org/obo/PATO_0000001	quality	http://purl.obolibrary.org/obo/BFO_0000020	specifically dependent continuant		A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities
http://purl.obolibrary.org/obo/PATO_0000025	composition	http://purl.obolibrary.org/obo/PATO_0000141	structure		A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts.
http://purl.obolibrary.org/obo/PATO_0000033	concentration of	http://purl.obolibrary.org/obo/PATO_0000070	amount		A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance.
http://purl.obolibrary.org/obo/PATO_0000051	morphology	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure.
http://purl.obolibrary.org/obo/PATO_0000070	amount	http://purl.obolibrary.org/obo/PATO_0103000	quantitative		The number of entities of this type that are part of the whole organism.
http://purl.obolibrary.org/obo/PATO_0000117	size	http://purl.obolibrary.org/obo/PATO_0000051	morphology		A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude.
http://purl.obolibrary.org/obo/PATO_0000140	position	http://purl.obolibrary.org/obo/PATO_0001018	physical quality		A spatial quality inhering in a bearer by virtue of the bearer's spatial location relative to other objects in the vicinity.
http://purl.obolibrary.org/obo/PATO_0000141	structure	http://purl.obolibrary.org/obo/PATO_0000051	morphology		A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form.
http://purl.obolibrary.org/obo/PATO_0000165	time	http://purl.obolibrary.org/obo/PATO_0001018	physical quality		A quality in which events occur in sequence.
http://purl.obolibrary.org/obo/PATO_0000169	viability	http://purl.obolibrary.org/obo/PATO_0001995	organismal quality		An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population.
http://purl.obolibrary.org/obo/PATO_0000402	branched	http://purl.obolibrary.org/obo/PATO_0000001	quality		A branchiness quality inhering in a bearer by virtue of the bearer's having branches.
http://purl.obolibrary.org/obo/PATO_0001018	physical quality	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities.
http://purl.obolibrary.org/obo/PATO_0001020	damage	http://purl.obolibrary.org/obo/PATO_0000141	structure		A structural quality inhering in a bearer by virtue of whether the bearer has been harmed or injured or spoiled.
http://purl.obolibrary.org/obo/PATO_0001199	linear	http://purl.obolibrary.org/obo/PATO_0000001	quality		A shape quality inhering in a bearer by virtue of the bearer's being narrow, with the two opposite margins parallel.
http://purl.obolibrary.org/obo/PATO_0001241	physical object quality	http://purl.obolibrary.org/obo/BFO_0000019	quality		A quality which inheres in a continuant.
http://purl.obolibrary.org/obo/PATO_0001296	luminous flux	http://purl.obolibrary.org/obo/PATO_0001300	optical quality		A scalar optical quality which obtains by the magnitude of the light emitted by the bearer.
http://purl.obolibrary.org/obo/PATO_0001300	optical quality	http://purl.obolibrary.org/obo/PATO_0070060	quality of interaction of a substance with electromagnetic radiation		An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light.
http://purl.obolibrary.org/obo/PATO_0001335	bacterial mating type	http://purl.obolibrary.org/obo/PATO_0001895	mating type		A mating type that indicates whether the F plasmid has integrated into the chromosome.
http://purl.obolibrary.org/obo/PATO_0001337	yeast mating type	http://purl.obolibrary.org/obo/PATO_0001895	mating type		A yeast mating type.
http://purl.obolibrary.org/obo/PATO_0001342	Saccharomyces cerevisiae mating type	http://purl.obolibrary.org/obo/PATO_0001337	yeast mating type		A S. cerevisiae mating type.
http://purl.obolibrary.org/obo/PATO_0001343	Schizosaccharomyces pombe mating type	http://purl.obolibrary.org/obo/PATO_0001337	yeast mating type		A S. pombe mating type determined by the gene configuration on the mat1 locus.
http://purl.obolibrary.org/obo/PATO_0001393	euploid	http://purl.obolibrary.org/obo/PATO_0001374	ploidy		A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes.
http://purl.obolibrary.org/obo/PATO_0001470	ratio	http://purl.obolibrary.org/obo/PATO_0000001	quality		A quality inhering in a bearer by virtue of the bearer's magnitude in proportion to the magnitude of another entity.
http://purl.obolibrary.org/obo/PATO_0001574	flow rate	http://purl.obolibrary.org/obo/PATO_0001906	movement quality		A physical quality inhering in a bearer by virtue of the bearer's motion characteristic.
http://purl.obolibrary.org/obo/PATO_0001708	1-D extent	http://purl.obolibrary.org/obo/PATO_0000117	size		A size quality inhering in an bearer by virtue of the bearer's extension in one dimension.
http://purl.obolibrary.org/obo/PATO_0001710	3-D extent	http://purl.obolibrary.org/obo/PATO_0000117	size		A size quality inhering in an bearer by virtue of the bearer's extension in three dimensions.
http://purl.obolibrary.org/obo/PATO_0001740	activity (of a radionuclide)	http://purl.obolibrary.org/obo/PATO_0002198	quality of a substance		A radiation quality inhering in a radioactive substance by virtue of its transformation (disintegration) rate.
http://purl.obolibrary.org/obo/PATO_0001894	phenotypic sex	http://purl.obolibrary.org/obo/PATO_0000047	biological sex		An organismal quality inhering in a bearer by virtue of the bearer's physical expression of sexual characteristics.
http://purl.obolibrary.org/obo/PATO_0001895	mating type	http://purl.obolibrary.org/obo/PATO_0000047	biological sex		A biological sex quality inhering in an individual or a population that undergo sexual reproduction.
http://purl.obolibrary.org/obo/PATO_0001906	movement quality	http://purl.obolibrary.org/obo/PATO_0001018	physical quality		A physical quality inhering in a bearer by virtue of the bearer's participation in movement.
http://purl.obolibrary.org/obo/PATO_0002003	population quality	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		A quality that inheres in an entire population or part of a population.
http://purl.obolibrary.org/obo/PATO_0002027	osmolality	http://purl.obolibrary.org/obo/PATO_0000033	concentration of		A concentration quality inhering in a bearer by virtue of the bearer's amount of osmoles of solute per kilogram of solvent.
http://purl.obolibrary.org/obo/PATO_0002124	laminar	http://purl.obolibrary.org/obo/PATO_0000001	quality		A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer.
http://purl.obolibrary.org/obo/PATO_0002198	quality of a substance	http://purl.obolibrary.org/obo/PATO_0001018	physical quality		A quality inhering in a bearer by virtue of its constitution.
http://purl.obolibrary.org/obo/UBERON_0036149	suprapubic skin	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Area of skin in the hypoastric region of the abdomen.
http://purl.obolibrary.org/obo/OBI_0002134	assay measuring epitope specific chemokine (C-C motif) ligand 20 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 20 production by T cells.
http://purl.obolibrary.org/obo/OBI_0002138	temperature value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that specifies the temperature of some thing.
http://purl.obolibrary.org/obo/OBI_0002139	volume value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that specifies the volume of some thing.
http://purl.obolibrary.org/obo/OBI_0002141	volume measurement assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay to determine the volume of an evaluant.
http://purl.obolibrary.org/obo/OBI_0002162	footprinting assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures ligand binding and conformational changes by the solvent accessibility of the backbone, bases, or side-chain structures of macromolecules through their sensitivity to chemical or enzymatic cleavage or modification reactions.
http://purl.obolibrary.org/obo/OBI_0002163	DNAse footprinting assay	http://purl.obolibrary.org/obo/OBI_0002162	footprinting assay		An enzymatic footprinting assay that determines protein-binding sites on DNA by identifying bound fragments that are protected from DNAse I-catalyzed hydrolysis
http://purl.obolibrary.org/obo/OBI_0002164	mammalian 2-hybrid assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay that increases the expression of a reporter gene in mammalian cells by proteins of interest attached to two portions of the transcriptional activator, bringing those portions closer together.
http://purl.obolibrary.org/obo/OBI_0002165	protein localization assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that determines the specific location of a protein. Subcellular localization is distinguished from tissue-based localization based on the type of microscopy applied.
http://purl.obolibrary.org/obo/OBI_0002166	tissue-based protein localization assay	http://purl.obolibrary.org/obo/OBI_0002165	protein localization assay		A protein localization assay that determines the specific location of a protein in a living tissue sample.
http://purl.obolibrary.org/obo/OBI_0002167	subcellular protein localization assay	http://purl.obolibrary.org/obo/OBI_0002165	protein localization assay		A protein localization assay that determines the specific subcellular location of a protein. The location is visualized through electron microscopy.
http://purl.obolibrary.org/obo/OBI_0002168	subcellular protein immunohistochemistry assay	http://purl.obolibrary.org/obo/OBI_0001986	immunohistochemistry		An immunohistochemistry assay that uses antibodies to display the specific subcellular location of proteins.
http://purl.obolibrary.org/obo/OBI_0002169	ChIP-qPCR assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay		A ChIP assay that uses quantitative PCR to determine levels of specific DNA in immunoprecipitated samples.
http://purl.obolibrary.org/obo/OBI_0002170	genomic SELEX	http://purl.obolibrary.org/obo/OBI_0002161	systematic evolution of ligands by exponential enrichment assay		A systematic evolution of ligands by exponential enrichment assay that starts with a library derived from genomic DNA instead of synthetically derived random DNA molecules.
http://purl.obolibrary.org/obo/OBI_0002173	Southwestern blot assay	http://purl.obolibrary.org/obo/OBI_0001591	direct binding assay		A direct binding assay that detects interactions of labeled DNA with immobilized protein on a membrane.
http://purl.obolibrary.org/obo/OBI_0002174	immunocytochemistry	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		An immuno staining assay in which samples of intact cells are examined that have had most, if not all, of their surrounding extracellular matrix removed
http://purl.obolibrary.org/obo/OBI_0002176	electrophysiology assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the electrical properties of biological cells or tissues. Typically, this assay will generate measurements of voltage changes or electric current (or other associated variables such as impedence or capacitance).
http://purl.obolibrary.org/obo/OBI_0002177	patch clamp assay	http://purl.obolibrary.org/obo/OBI_0000447	intracellular electrophysiology recording assay		An intracellular electrophysiology assay where a glass micropipette is sealed to the surface of the cell membrane as a recording electrode to study ion channel activity. The key distinction of this technique is the electrical resistance of the seal between the cell membrane and the pipette is of the order 10-100 gigaohms, permitting high-resolution current measurements over the cell membrane in several different standard configurations.
http://purl.obolibrary.org/obo/OBI_0002178	whole-cell patch clamp assay	http://purl.obolibrary.org/obo/OBI_0002177	patch clamp assay		A patch-clamp assay where the electrode is left in place on the cell, as in cell-attached recordings, but the membrane patch has been perforated, providing access from the interior of the pipette to the intracellular space of the cell. Measurements made with this technique involve recording currents through multiple channels simultaneously, over the membrane of the entire cell.
http://purl.obolibrary.org/obo/OBI_0002179	cell-attached patch clamp assay	http://purl.obolibrary.org/obo/OBI_0002177	patch clamp assay		A patch-clamp assay where the electrode is left in place on the cell, and the membrane patch has been left intact been perforated. This maintains the separation of the interior of the pipette to the intracellular space of the cell. Measurements made with this technique involve recording currents through multiple channels simultaneously, over the membrane of the entire cell.
http://purl.obolibrary.org/obo/OBI_0002180	inside-out patch clamp assay	http://purl.obolibrary.org/obo/OBI_0002177	patch clamp assay		A patch-clamp assay where a patch of the membrane is attached to the patch pipette, detached from the rest of the cell, and the cytosolic surface of the membrane is exposed to the external media, or bath. This provides the experimenter has access to the intracellular surface of the membrane via the bath and can manipulate the environment at the intracellular surface of single ion channels. For example, channels that are activated by intracellular ligands can then be studied through a range of ligand concentrations.
http://purl.obolibrary.org/obo/OBI_0002181	outside-out patch clamp assay	http://purl.obolibrary.org/obo/OBI_0002177	patch clamp assay		A patch-clamp assay where a patch of the membrane is attached to the patch pipette. In this configuration, the external surface of the cell membrane is exposed as the outside of the membrane patch relative to the patch electrode. An outside-out patch starts with a gigaohm seal in a whole-cell recording configuration. The electrode is slowly withdrawn from the cell, until a fragment of membrane bulges away from the cell, which detaches and reforms as a convex membrane on the end of the electrode, with the original external surface of the membrane facing outward from the electrode. This provides the experimenter with access to the extracellular surface of the membrane via the bath and can manipulate the environment at the extracellular surface of single ion channels.
http://purl.obolibrary.org/obo/OBI_0002182	voltage clamp assay	http://purl.obolibrary.org/obo/OBI_0000447	intracellular electrophysiology recording assay		An cellular electrophysiology assay where the membrane potential of a cell is controlled by the experimentalist. This is accomplished through a feedback mechanism where any change in membrane potential is countered by permitting electrical current to flow into or out of the cell.
http://purl.obolibrary.org/obo/OBI_0002185	current clamp assay	http://purl.obolibrary.org/obo/OBI_0000447	intracellular electrophysiology recording assay		The current clamp technique records the membrane potential by injecting current into a cell through the recording electrode. Unlike in the voltage clamp mode, where the membrane potential is held at a level determined by the experimenter, in "current clamp" mode the membrane potential is free to vary, and the amplifier records whatever voltage the cell generates on its own or as a result of stimulation. This technique is used to study how a cell responds when electric current enters a cell; this is important for instance for understanding how neurons respond to neurotransmitters that act by opening membrane ion channels.
http://purl.obolibrary.org/obo/OBI_0002187	single-unit recording	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		An extracellular electrophysiology assay where a single microelectrode is placed in close proximity to a single neuron to measure voltage and current changes over time. This is the technicque used by Hubel and Wiesel to measure firing properties of primary visual cortex neurons in the 1950s in their original Nobel-prize winning study. A classic, old technique.
http://purl.obolibrary.org/obo/OBI_0002188	multi-unit recording	http://purl.obolibrary.org/obo/OBI_0000454	extracellular electrophysiology recording assay		An extracellular electrophysiology assay where a collection of microelectrodes (often in an 'array' configuration) is placed into neural tissue to measure the distribution of voltage and current changes for a population of cells over time.
http://purl.obolibrary.org/obo/OBI_0002189	local field potential recording	http://purl.obolibrary.org/obo/OBI_0000454	extracellular electrophysiology recording assay		An extracellular electrophysiology assay where a microelectrode is placed in the extracellular space of brain tissue to measure action potential and compared to an electrode either outside or inside that tissue.
http://purl.obolibrary.org/obo/OBI_0002544	esophagogastric junction specimen	http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen		A specimen that is derived from the esophagogastric junction.
http://purl.obolibrary.org/obo/OBI_0002545	ileum specimen	http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen		A specimen that is derived from ileum.
http://purl.obolibrary.org/obo/OBI_0002546	liver specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from liver.
http://purl.obolibrary.org/obo/OBI_0002547	minor salivary gland specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from minor salivary gland.
http://purl.obolibrary.org/obo/OBI_0002548	omentum specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from omentum.
http://purl.obolibrary.org/obo/OBI_0002549	ovary specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from female gonad.
http://purl.obolibrary.org/obo/OBI_0002551	suprapubic skin specimen	http://purl.obolibrary.org/obo/OBI_0002526	skin of body specimen		A specimen that is derived from suprapubic skin.
http://purl.obolibrary.org/obo/OBI_0002552	testis specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from testis.
http://purl.obolibrary.org/obo/OBI_0002553	uterus specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from uterus.
http://purl.obolibrary.org/obo/OBI_0002555	age group inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states an age bracket which, if met, makes an entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002556	minimum age value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specifcation that specifies the youngest age when specifying an age range.
http://purl.obolibrary.org/obo/OBI_0002557	maximum age value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specifcation that specifies the oldest age when specifying an age range.
http://purl.obolibrary.org/obo/OBI_0002558	use of medication inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states a a set of medications, which, if used by an entity, makes that entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002559	hospital patient inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion defines that a human being has to be a hospital patient to be suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002560	family status inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more family statuses, which, if met, makes a human being suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002561	sex inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more sexes which, if met, makes an entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002562	country of residence inclusion criteria	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more countries of residence which, if met, makes a human being suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002563	ethnicity inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criteria that defines and states one or more ethnicities which, if met, makes an entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002564	histopathology assay	http://purl.obolibrary.org/obo/OBI_0600020	histological assay		A histological assay that is intended to check for the presence or level of a specific disease.
http://purl.obolibrary.org/obo/UBERON_8470000	placental blood	http://purl.obolibrary.org/obo/UBERON_0000178	blood		Blood located in the placenta.
http://purl.obolibrary.org/obo/OBI_0003335	diffusion weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003334	reconstructed magnetic resonance image data set		A type of magnetic resonance image data set collected using at least three diffusion gradients of some factor "b," which is a function of the amplitude, duration, and interval of the gradiants.
http://purl.obolibrary.org/obo/OBI_0003338	task-based functional magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003336	functional magnetic resonance image data set		A type of functional MRI in which the participant is given a task or tasks, which are timed with the acquisition
http://purl.obolibrary.org/obo/OBI_0003339	perfusion weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003334	reconstructed magnetic resonance image data set		An magnetic resonance image data set that captures volume and flow of blood in the brain.
http://purl.obolibrary.org/obo/OBI_0003340	proton density magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003334	reconstructed magnetic resonance image data set		An magnetic resonance image data set in which the contrast emphasizes density of protons, supressing T1 and T2 effects
http://purl.obolibrary.org/obo/OBI_0003341	T1 weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003334	reconstructed magnetic resonance image data set		An magnetic resonance image acquired using a T1 weighted magnetic resonance image acquisition sequence.
http://purl.obolibrary.org/obo/OBI_0003342	post-Gd T1 weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003341	T1 weighted magnetic resonance image data set		A T1 weighted image data set where gadolidium contrast agent has been administered to the participant before image acquistion.
http://purl.obolibrary.org/obo/OBI_0003343	T1 weighted GRE magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003341	T1 weighted magnetic resonance image data set		T1 weighted image data set collected using a gradient recall echo sequence.
http://purl.obolibrary.org/obo/OBI_0003344	high resolution T1 weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003343	T1 weighted GRE magnetic resonance image data set		A T1-weighted image data set acquired from an NMR/MRI machine with at least a 3 Tesla magnet and in which the voxel size is isotropic.
http://purl.obolibrary.org/obo/OBI_0003345	baseline high resolution T1 weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003343	T1 weighted GRE magnetic resonance image data set		A T1w image data set collected at an evaluant's first visit in a study.
http://purl.obolibrary.org/obo/OBI_0003346	follow-up high resolution T1 weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003343	T1 weighted GRE magnetic resonance image data set		A T1w image data set collected at a later time than the evaluant's first scan.
http://purl.obolibrary.org/obo/OBI_0003347	T1 weighted SE magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003341	T1 weighted magnetic resonance image data set		A T1 weighted image data set acquired using a spin echo sequence.
http://purl.obolibrary.org/obo/OBI_0003348	T2 weighted magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003334	reconstructed magnetic resonance image data set		A magnetic resonance image produced by a T2 weighted magnetic resonance image acquisition sequence.
http://purl.obolibrary.org/obo/OBI_0003349	T2 weighted FLAIR magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003348	T2 weighted magnetic resonance image data set		A T2 weighted image data set collected using a FLAIR sequence.
http://purl.obolibrary.org/obo/OBI_0003351	T2 weighted SE magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003348	T2 weighted magnetic resonance image data set		A type of T2-weighted image in which the acquisition is performed using a 2D spin-echo technique
http://purl.obolibrary.org/obo/OBI_0003352	T2 weighted STIR magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003348	T2 weighted magnetic resonance image data set		A T2 weighted magnetic resonance image data set collected using a STIR sequence to suppress the signal coming from fat.
http://purl.obolibrary.org/obo/OBI_0003353	T2* weighted GRE magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003348	T2 weighted magnetic resonance image data set		T2* weighted image data set collected using a gradient echo sequence.
http://purl.obolibrary.org/obo/OBI_0003357	brain region atlas image data set	http://purl.obolibrary.org/obo/OBI_0003333	computed image data set		An image data set consisting of values computed from multiple image data sets encoded to represent the spatial location of individual functional or structural regions of a canonical brain.
http://purl.obolibrary.org/obo/OBI_0003358	probabilistic brain region atlas image dataset	http://purl.obolibrary.org/obo/OBI_0003357	brain region atlas image data set		A brain atlas consisting of weighted values that respresent the probability that a voxel X is part of some brain component Y, typically derived from multiple image data sets.
http://purl.obolibrary.org/obo/OBI_0003359	deterministic brain region atlas image data set	http://purl.obolibrary.org/obo/OBI_0003357	brain region atlas image data set		A brain atlas consisting of discrete integer values where a value X denotes a voxel is part of some brain component Y.
http://purl.obolibrary.org/obo/OBI_0003360	image segmentation map	http://purl.obolibrary.org/obo/OBI_0003333	computed image data set		An image data set of integer values in which each value corresponds to some shared characteristic or computed property. The values often belong to a group of pixels or voxels that share the same characteristic, such as a tissue type or anatomical region.
http://purl.obolibrary.org/obo/OBI_0003361	lesion mask	http://purl.obolibrary.org/obo/OBI_0003360	image segmentation map		An image data set where voxel intensity values greater than zero encode the location of some brain lesion and voxels outside the lesion have an intensity value of zero.
http://purl.obolibrary.org/obo/OBI_0003362	T1 lesion mask	http://purl.obolibrary.org/obo/OBI_0003361	lesion mask		A lesion mask where the lesions are derived from a T1 weighted image data set.
http://purl.obolibrary.org/obo/OBI_0003363	T2 FLAIR lesion mask	http://purl.obolibrary.org/obo/OBI_0003361	lesion mask		A lesion mask where the lesions are derived from a T2 FLAIR image data set.
http://purl.obolibrary.org/obo/OBI_0003553	intragastric administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the stomach of an organism.
http://purl.obolibrary.org/obo/OBI_0003554	intracolonic administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the colon of an organism.
http://purl.obolibrary.org/obo/OBI_0003555	vaginal administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the vagina of an organism.
http://purl.obolibrary.org/obo/OBI_0003557	cervical administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance to the cervix of an organism.
http://purl.obolibrary.org/obo/OBI_0003558	conjunctival administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance to the conjunctiva of an organism.
http://purl.obolibrary.org/obo/OBI_0003559	intratracheal administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the trachea of an organism.
http://purl.obolibrary.org/obo/OBI_0003560	intra-amniotic administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the amnion of an organism.
http://purl.obolibrary.org/obo/OBI_0003561	intra-arterial administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the artery of an organism.
http://purl.obolibrary.org/obo/OBI_0003562	intracerebral administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the cerebrum of an organism.
http://purl.obolibrary.org/obo/OBI_0003563	intracranial administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the cranium of an organism.
http://purl.obolibrary.org/obo/OBI_0003564	intraepidermal administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the epidermis of an organism.
http://purl.obolibrary.org/obo/OBI_0003565	intralymphatic administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the lymphatic system of an organism.
http://purl.obolibrary.org/obo/OBI_0003566	lymph node administration	http://purl.obolibrary.org/obo/OBI_0003565	intralymphatic administration		An intralymphatic administration in which the substance is administered into a lymph node.
http://purl.obolibrary.org/obo/OBI_0003567	urethral administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the urethra of an organism.
http://purl.obolibrary.org/obo/OBI_0003568	skin scarification administration	http://purl.obolibrary.org/obo/OBI_0003564	intraepidermal administration		An intraepidermal administration in which the skin is scratched before the substance is administered to the skin.
http://purl.obolibrary.org/obo/OBI_0003569	intrauteral administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An adminstration of a substance into the uterus of an organism.
http://purl.obolibrary.org/obo/OBI_0003571	intraocular administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance to the eye of an organism.
http://purl.obolibrary.org/obo/OBI_0003572	intraplacental administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the placenta of an organism.
http://purl.obolibrary.org/obo/OBI_0003573	intrarectal administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the rectum of an organism.
http://purl.obolibrary.org/obo/OBI_0003574	intrasplenic administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into the spleen of an organism.
http://purl.obolibrary.org/obo/OBI_0003603	intratumoral administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of a substance into a tumor of an organism.
http://purl.obolibrary.org/obo/OBI_0003607	disease causation objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification that is fulfilled by causing a disease in a particular organism.
http://purl.obolibrary.org/obo/OBI_0003609	disease prevention objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification that is fulfilled by preventing the development of a disease in a particular organism.
http://purl.obolibrary.org/obo/OBI_0003610	reactant role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role borne by a biological or chemical entity that participates or has molecular components that participate in a chemical reaction.
http://purl.obolibrary.org/obo/OBI_0003611	precursor role	http://purl.obolibrary.org/obo/OBI_0003610	reactant role		A role borne by a biological or chemical entity which serves as the core component of a chemical reaction process, upon which other reactants, like reagents or solvents, act.
http://purl.obolibrary.org/obo/OBI_0003612	electron microscopy assay determining the 3D structure of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0003118	electron-microscopy 3D molecular structure determination assay		An electron-microscopy 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a T cell epitope:MHC:TCR complex.
http://purl.obolibrary.org/obo/OBI_0003613	electron microscopy assay determining the 3D structure of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0003118	electron-microscopy 3D molecular structure determination assay		An electron-microscopy 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a MHC:ligand complex.
http://purl.obolibrary.org/obo/OBI_0003614	disease prevalence reduction objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification that is fulfilled by reducing the prevalence of a disease in a population of organisms.
http://purl.obolibrary.org/obo/OBI_0003615	antibody purification of MHC protein complex	http://purl.obolibrary.org/obo/OBI_0001505	purification		A purification to separate a material entity into different compositions of which one fraction contains a higher concentration of MHC protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003616	antibody purification of MHC class I protein complex	http://purl.obolibrary.org/obo/OBI_0003615	antibody purification of MHC protein complex		An antibody purification of MHC protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of MHC class I protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003617	antibody purification of human MHC class I protein complex	http://purl.obolibrary.org/obo/OBI_0003635	antibody purification of pig MHC class I protein complex, cattle MHC class I protein complex, and/or human MHC class I protein complex		An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of human MHC class I protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003618	antibody purification of HLA protein complex with A2 serotype	http://purl.obolibrary.org/obo/OBI_0003620	antibody purification of HLA protein complex with A2 serotype and/or HLA protein complex with A28 serotype		An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A2 serotype, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003619	antibody purification of HLA protein complex with A24 serotype	http://purl.obolibrary.org/obo/OBI_0003617	antibody purification of human MHC class I protein complex		An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A24 serotype, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003620	antibody purification of HLA protein complex with A2 serotype and/or HLA protein complex with A28 serotype	http://purl.obolibrary.org/obo/OBI_0003617	antibody purification of human MHC class I protein complex		An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A2 serotype and/or HLA protein complex with A28 serotype, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003621	antibody purification of HLA protein complex with A29 serotype	http://purl.obolibrary.org/obo/OBI_0003617	antibody purification of human MHC class I protein complex		An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A29 serotype, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003622	antibody purification of HLA protein complex with B27 serotype	http://purl.obolibrary.org/obo/OBI_0003617	antibody purification of human MHC class I protein complex		An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with B27 serotype, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003623	antibody purification of HLA-C protein complex	http://purl.obolibrary.org/obo/OBI_0003617	antibody purification of human MHC class I protein complex		An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA-C protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003624	antibody purification of pig MHC class I protein complex	http://purl.obolibrary.org/obo/OBI_0003635	antibody purification of pig MHC class I protein complex, cattle MHC class I protein complex, and/or human MHC class I protein complex		An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of pig MHC class I protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003625	antibody purification of cattle MHC class I protein complex	http://purl.obolibrary.org/obo/OBI_0003635	antibody purification of pig MHC class I protein complex, cattle MHC class I protein complex, and/or human MHC class I protein complex		An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of cattle MHC class I protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003626	antibody purification of rat MHC class I protein complex	http://purl.obolibrary.org/obo/OBI_0003616	antibody purification of MHC class I protein complex		An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of rat MHC class I protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003627	antibody purification of mouse MHC class I protein complex	http://purl.obolibrary.org/obo/OBI_0003616	antibody purification of MHC class I protein complex		An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of mouse MHC class I protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003628	antibody purification of H2-Dd protein complex	http://purl.obolibrary.org/obo/OBI_0003632	antibody purification of H2-Dd protein complex and/or H2-Kd protein complex		An antibody purification of mouse MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-Dd protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003629	antibody purification of H2-Db protein complex	http://purl.obolibrary.org/obo/OBI_0003631	antibody purification of H2-Ld protein complex, H2-Db protein complex, and/or H2-Dq protein complex		An antibody purification of mouse MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-Db protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003630	antibody purification of H2-Kd protein complex	http://purl.obolibrary.org/obo/OBI_0003632	antibody purification of H2-Dd protein complex and/or H2-Kd protein complex		An antibody purification of mouse MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-Kd protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003632	antibody purification of H2-Dd protein complex and/or H2-Kd protein complex	http://purl.obolibrary.org/obo/OBI_0003627	antibody purification of mouse MHC class I protein complex		An antibody purification of mouse MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-Dd protein complex and/or H2-Kd protein complex while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003633	antibody purification of mouse MHC class I protein complex with H2-b haplotype and/or mouse MHC protein complex with H2-p haplotype	http://purl.obolibrary.org/obo/OBI_0003627	antibody purification of mouse MHC class I protein complex		An antibody purification of mouse MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of mouse MHC class I protein complex with H2-b haplotype and/or mouse MHC protein complex with H2-p haplotype while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003634	antibody purification of H2-Kb protein complex, H2-Ks protein complex, and/or H2-Kq protein complex	http://purl.obolibrary.org/obo/OBI_0003627	antibody purification of mouse MHC class I protein complex		An antibody purification of mouse MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of mouse H2-Kb protein complex, H2-Ks protein complex, and/or H2-Kq protein complex while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003635	antibody purification of pig MHC class I protein complex, cattle MHC class I protein complex, and/or human MHC class I protein complex	http://purl.obolibrary.org/obo/OBI_0003616	antibody purification of MHC class I protein complex		An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of pig MHC class I protein complex, cattle MHC class I protein complex, and/or human MHC class I protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003636	antibody purification of MHC class II protein complex	http://purl.obolibrary.org/obo/OBI_0003615	antibody purification of MHC protein complex		An antibody purification of MHC protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of MHC class II protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003637	antibody purification of cattle MHC class II protein complex	http://purl.obolibrary.org/obo/OBI_0003636	antibody purification of MHC class II protein complex		An antibody purification of MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of cattle MHC class II protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003638	antibody purification of human MHC class II protein complex	http://purl.obolibrary.org/obo/OBI_0003636	antibody purification of MHC class II protein complex		An antibody purification of MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of human MHC class II protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003639	antibody purification of HLA-DP protein complex	http://purl.obolibrary.org/obo/OBI_0003638	antibody purification of human MHC class II protein complex		An antibody purification of human MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA-DP protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003640	antibody purification of HLA-DR protein complex	http://purl.obolibrary.org/obo/OBI_0003638	antibody purification of human MHC class II protein complex		An antibody purification of human MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA-DR protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003641	antibody purification of HLA protein complex with DQ3 serotype	http://purl.obolibrary.org/obo/OBI_0003638	antibody purification of human MHC class II protein complex		An antibody purification of human MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with DQ3 serotype, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003642	antibody purification of mouse MHC class II protein complex	http://purl.obolibrary.org/obo/OBI_0003646	antibody purification of mouse MHC class II protein complex and/or rat MHC class II protein complex with RT1-A haplotype		An antibody purification of MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of mouse MHC class II protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003643	antibody purification of H2-IA protein complex	http://purl.obolibrary.org/obo/OBI_0003642	antibody purification of mouse MHC class II protein complex		An antibody purification of mouse MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-IA protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003644	antibody purification of H2-IAg7 protein complex	http://purl.obolibrary.org/obo/OBI_0003643	antibody purification of H2-IA protein complex		An antibody purification of mouse MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-IAg7 protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003645	antibody purification of H2-IAd protein complex	http://purl.obolibrary.org/obo/OBI_0003643	antibody purification of H2-IA protein complex		An antibody purification of mouse MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-IAd protein complex, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003646	antibody purification of mouse MHC class II protein complex and/or rat MHC class II protein complex with RT1-A haplotype	http://purl.obolibrary.org/obo/OBI_0003636	antibody purification of MHC class II protein complex		An antibody purification of MHC class II protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of mouse MHC class II protein complex and/or rat MHC class II protein complex with RT1-A haplotype, while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003650	Illumina Infinium MethylationEPIC v2.0 BeadChip	http://purl.obolibrary.org/obo/OBI_0001870	Illumina methylation BeadChip		An Illumina methylation BeadChip that targets  935,000 methylation sites per sample at single-nucleotide resolution.
http://purl.obolibrary.org/obo/OBI_0003651	multidimensional fatigue inventory score	http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item		A clinical data item that quantifies the severity of a person's fatigue as measured by a 20-item self-report instrument.
http://purl.obolibrary.org/obo/OBI_0003686	chromatin accessibility assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that determines which regions of a DNA molecule are in the form of euchromatin and thus able to make direct physical contact with (i.e. are accessible to) other molecules such as RNA polymerase, transcription factors, etc.
http://purl.obolibrary.org/obo/OBI_0003708	infrared gas analyzer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A measurement device that measures the concentration of gases in an air sample based on their absorption of infrared radiation.
http://purl.obolibrary.org/obo/OBI_0003726	maximum data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation that has as its output the greatest value in the input data set.
http://purl.obolibrary.org/obo/OBI_0003734	clinical history collection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		A clinical assay that produces a data item indicating whether an organism has ever had a particular disease, lifestyle factor, immune exposure, or medical procedure.
http://purl.obolibrary.org/obo/OBI_0003735	disease severity assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the severity of a disease in an organism.
http://purl.obolibrary.org/obo/OBI_0003736	genetic characteristic assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that produces information about a genetic characteristic of an organism.
http://purl.obolibrary.org/obo/OBI_0004001	randomized clinical trial	http://purl.obolibrary.org/obo/OBI_0003699	clinical trial		A clinical trial in which the participants are divided by chance into separate groups that compare different treatments or other interventions. Using chance to divide people into groups means that the groups will be similar and that the effects of the treatments they receive can be compared more fairly. At the time of the trial, it is not known which treatment is best.
http://purl.obolibrary.org/obo/HP_0000855	Insulin resistance	http://purl.obolibrary.org/obo/BFO_0000016	disposition		Increased resistance towards insulin, that is, diminished effectiveness of insulin in reducing blood glucose levels.
http://purl.obolibrary.org/obo/HP_0002664	Neoplasm	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		An organ or organ-system abnormality that consists of uncontrolled autonomous cell-proliferation which can occur in any part of the body as a benign or malignant neoplasm (tumor).
http://purl.obolibrary.org/obo/UBERON_0000002	uterine cervix	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Lower, narrow portion of the uterus where it joins with the top end of the vagina.
http://purl.obolibrary.org/obo/UBERON_0000057	urethra	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The fibromuscular tubular canal through which urine is discharged from the bladder to the exterior via the external urinary meatus; in males, the urethra is joined by the ejaculatory ducts and serves as a passageway for semen during ejaculation, as well as a canal for urine during voiding; in females, the urethra is shorter and emerges above the vaginal opening.
http://purl.obolibrary.org/obo/UBERON_0000473	testis	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A gonad of a male animal. A gonad produces and releases sperm.
http://purl.obolibrary.org/obo/UBERON_0000947	aorta	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation.
http://purl.obolibrary.org/obo/UBERON_0001003	skin epidermis	http://purl.obolibrary.org/obo/UBERON_0000483	epithelium		The outer epithelial layer of the skin that is superficial to the dermis.
http://purl.obolibrary.org/obo/UBERON_0001037	strand of hair	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A filament, mostly protein, that grows from follicles found in the dermis[WP].
http://purl.obolibrary.org/obo/UBERON_0001264	pancreas	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		An endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating hormones[GO].
http://purl.obolibrary.org/obo/UBERON_0001557	upper respiratory tract	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The segment of the respiratory tract that starts proximally with the nose and ends distally with the cricoid cartilage, before continuing to the trachea.
http://purl.obolibrary.org/obo/UBERON_0001621	coronary artery	http://purl.obolibrary.org/obo/UBERON_0001637	artery		An artery that supplies the myocardium.
http://purl.obolibrary.org/obo/UBERON_0001638	vein	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Any of the tubular branching vessels that carry blood from the capillaries toward the heart.
http://purl.obolibrary.org/obo/UBERON_0001728	nasopharynx	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The section of the pharynx that lies above the soft palate.
http://purl.obolibrary.org/obo/UBERON_0001729	oropharynx	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The portion of the pharynx that lies between the soft palate and the upper edge of the epiglottis.
http://purl.obolibrary.org/obo/UBERON_0001797	vitreous humor	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		A transparent, semigelatinous substance that fills the cavity behind the crystalline lens of the eye and in front of the retina.
http://purl.obolibrary.org/obo/UBERON_0001893	telencephalon	http://purl.obolibrary.org/obo/UBERON_0000481	multi-tissue structure		Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres.
http://purl.obolibrary.org/obo/UBERON_0001987	placenta	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin[GO]. The fetal portion of the placenta is known as the villous chorion. The maternal portion is known as the decidua basalis. The two portions are held together by anchoring villi that are anchored to the decidua basalis by the cytotrophoblastic shell.
http://purl.obolibrary.org/obo/UBERON_0002037	cerebellum	http://purl.obolibrary.org/obo/UBERON_0000481	multi-tissue structure		Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA].
http://purl.obolibrary.org/obo/UBERON_0002067	dermis	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP].
http://purl.obolibrary.org/obo/UBERON_0002369	adrenal gland	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Either of a pair of complex endocrine organs near the anterior medial border of the kidney consisting of a mesodermal cortex that produces glucocorticoid, mineralocorticoid, and androgenic hormones and an ectodermal medulla that produces epinephrine and norepinephrine[BTO].
http://purl.obolibrary.org/obo/UBERON_0002371	bone marrow	http://purl.obolibrary.org/obo/UBERON_0000479	tissue		The soft tissue that fills the cavities of bones.
http://purl.obolibrary.org/obo/UBERON_0002386	forelimb zeugopod	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The middle limb segment of the pectoral free limb, between the autopod and stylopod segments. Includes as parts the forelimb zeugopodial skeleton, which includes as parts the radius and ulna, or their cartilage precursors, or evolutionary variants.
http://purl.obolibrary.org/obo/UBERON_0007650	esophagogastric junction	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The junction between the esophagus and the stomach epithelium.
http://purl.obolibrary.org/obo/BFO_0000002	continuant	http://purl.obolibrary.org/obo/BFO_0000001	entity		An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
http://purl.obolibrary.org/obo/BFO_0000003	occurrent	http://purl.obolibrary.org/obo/BFO_0000001	entity		An entity that has temporal parts and that happens, unfolds or develops through time.
http://purl.obolibrary.org/obo/BFO_0000004	independent continuant	http://purl.obolibrary.org/obo/BFO_0000002	continuant		b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002])
http://purl.obolibrary.org/obo/BFO_0000015	process	http://purl.obolibrary.org/obo/BFO_0000003	occurrent		p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003])
http://purl.obolibrary.org/obo/BFO_0000017	realizable entity	http://purl.obolibrary.org/obo/BFO_0000020	specifically dependent continuant		A specifically dependent continuant  that inheres in continuant  entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances.
http://purl.obolibrary.org/obo/BFO_0000020	specifically dependent continuant	http://purl.obolibrary.org/obo/BFO_0000002	continuant		b is a relational specifically dependent continuant = Def. b is a specifically dependent continuant and there are n &gt; 1 independent continuants c1, … cn which are not spatial regions are such that for all 1  i &lt; j  n, ci  and cj share no common parts, are such that for each 1  i  n, b s-depends_on ci at every time t during the course of b’s existence (axiom label in BFO2 Reference: [131-004])
http://purl.obolibrary.org/obo/BFO_0000023	role	http://purl.obolibrary.org/obo/BFO_0000017	realizable entity		A realizable entity  the manifestation of which brings about some result or end that is not essential to a continuant  in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant  in some kinds of natural, social or institutional contexts.
http://purl.obolibrary.org/obo/BFO_0000031	generically dependent continuant	http://purl.obolibrary.org/obo/BFO_0000002	continuant		b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001])
http://purl.obolibrary.org/obo/BFO_0000035	process boundary	http://purl.obolibrary.org/obo/BFO_0000003	occurrent		p is a process boundary =Def. p is a temporal part of a process & p has no proper temporal parts. (axiom label in BFO2 Reference: [084-001])
http://purl.obolibrary.org/obo/BFO_0000040	material entity	http://purl.obolibrary.org/obo/BFO_0000004	independent continuant		An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
http://purl.obolibrary.org/obo/BFO_0000140	continuant fiat boundary	http://purl.obolibrary.org/obo/BFO_0000141	immaterial entity		b is a continuant fiat boundary = Def. b is an immaterial entity that is of zero, one or two dimensions and does not include a spatial region as part. (axiom label in BFO2 Reference: [029-001])
http://purl.obolibrary.org/obo/BFO_0000144	process profile	http://purl.obolibrary.org/obo/BFO_0000015	process		b is a process_profile =Def. there is some process c such that b process_profile_of c (axiom label in BFO2 Reference: [093-002])
http://purl.obolibrary.org/obo/BFO_0000145	relational quality	http://purl.obolibrary.org/obo/BFO_0000019	quality		b is a relational quality = Def. for some independent continuants c, d and for some time t: b quality_of c at t & b quality_of d at t. (axiom label in BFO2 Reference: [057-001])
http://purl.obolibrary.org/obo/CLO_0000001	cell line cell	http://purl.obolibrary.org/obo/OBI_0001866	secondary cultured cell		A cultured cell that is part of a cell line - a stable and homogeneous population of cells with a common biological origin and propagation history in culture

http://purl.obolibrary.org/obo/CLO_0000018	mortal cell line cell	http://purl.obolibrary.org/obo/CLO_0000001	cell line cell		A cell line cell that is capable of replicating a limited number of times in culture before undergoing senescence.
http://purl.obolibrary.org/obo/CLO_0000019	immortal cell line cell	http://purl.obolibrary.org/obo/CLO_0000001	cell line cell		A cell line cell that is expected to be capable of an unlimited number of divisions, and is thus able to support indefinite propagation in vitro as part of an immortal cell line.
http://purl.obolibrary.org/obo/CLO_0000031	cell line	http://purl.obolibrary.org/obo/OBI_0001905	secondary cultured cell population		A cultured cell population that represents a genetically stable and homogenous population of cultured cells that shares a common propagation history (i.e. has been successively passaged together in culture).  

http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line	http://purl.obolibrary.org/obo/CLO_0000031	cell line		A cell line that is expected to be capable of indefinite propagation in an vitro culture.
http://purl.obolibrary.org/obo/CLO_0009829	mortal cell line	http://purl.obolibrary.org/obo/CLO_0000031	cell line		A cell line is able to support only a limited number of passages in vitro.
http://purl.obolibrary.org/obo/ENVO_00001998	soil	http://purl.obolibrary.org/obo/BFO_0000040	material entity		An environmental material which is primarily composed of minerals, varying proportions of sand, silt, and clay, organic material such as humus, interstitial gases, liquids, and a broad range of resident micro- and macroorganisms.
http://purl.obolibrary.org/obo/ENVO_00002257	podzol	http://purl.obolibrary.org/obo/ENVO_00001998	soil		Podzols are soils with a typically ash-grey upper subsurface horizon, bleached by loss of organic matter and iron oxides, on top of a dark accumulation horizon with brown, reddish or black illuviated humus and/or reddish Fe compounds. Podzols occur in humid areas in the boreal and temperate zones and locally also in the tropics.
http://purl.obolibrary.org/obo/ENVO_00010483	environmental material	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity which other material entities in an environmental system are primarily or partially composed of.
http://purl.obolibrary.org/obo/GAZ_00000448	geographic location	http://purl.obolibrary.org/obo/BFO_0000029	site		A reference to a place on the Earth, by its name or by its geographical location.
http://purl.obolibrary.org/obo/IAO_0000001	conditional specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A directive information entity that specifies what should happen if the trigger condition is fulfilled.
http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label	http://purl.obolibrary.org/obo/IAO_0000009	datum label		A measurement unit label is as a label that is part of a scalar measurement datum and denotes a unit of measure.
http://purl.obolibrary.org/obo/IAO_0000005	objective specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A directive information entity that describes an intended process endpoint. When part of a plan specification the concretization is realized in a planned process in which the bearer tries to effect the world so that the process endpoint is achieved.
http://purl.obolibrary.org/obo/IAO_0000006	narrative object	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A narrative object is an information content entity that is a set of propositions.
http://purl.obolibrary.org/obo/IAO_0000009	datum label	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A label is a symbol that is part of some other datum and is used to either partially define  the denotation of that datum or to provide a means for identifying the datum as a member of the set of data with the same label
http://purl.obolibrary.org/obo/IAO_0000010	software	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		Software is a plan specification composed of a series of instructions that can be 
interpreted by or directly executed by a processing unit.
http://purl.obolibrary.org/obo/IAO_0000027	data item	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that is intended to be a truthful statement about something (modulo, e.g., measurement precision or other systematic errors) and is constructed/acquired by a method which reliably tends to produce (approximately) truthful statements.
http://purl.obolibrary.org/obo/IAO_0000028	symbol	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity.
http://purl.obolibrary.org/obo/IAO_0000030	information content entity	http://purl.obolibrary.org/obo/BFO_0000031	generically dependent continuant		A generically dependent continuant that is about some thing.
http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A scalar measurement datum is a measurement datum that is composed of two parts, numerals and a unit label.
http://purl.obolibrary.org/obo/IAO_0000033	directive information entity	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity whose concretizations indicate to their bearer how to realize them in a process.
http://purl.obolibrary.org/obo/IAO_0000037	dot plot	http://purl.obolibrary.org/obo/IAO_0000038	graph		A dot plot is a report graph which is a graphical representation of data where each data point is represented by a single dot placed on coordinates corresponding to data point values in particular dimensions.
http://purl.obolibrary.org/obo/IAO_0000038	graph	http://purl.obolibrary.org/obo/IAO_0000308	figure		A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way.
http://purl.obolibrary.org/obo/IAO_0000055	rule	http://purl.obolibrary.org/obo/IAO_0000001	conditional specification		A rule is an executable which guides, defines, restricts actions.
http://purl.obolibrary.org/obo/IAO_0000064	algorithm	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which describes the inputs and output of mathematical functions as well as workflow of execution for achieving an predefined objective. Algorithms are realized usually by means of implementation as computer programs for execution by automata.
http://purl.obolibrary.org/obo/IAO_0000078	curation status specification	http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part		The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
http://purl.obolibrary.org/obo/IAO_0000079	density plot	http://purl.obolibrary.org/obo/IAO_0000038	graph		A density plot is a report graph which is a graphical representation of data where the tint of a particular pixel corresponds to some kind of function corresponding the the amount of data points relativelly with their distance from the the pixel.
http://purl.obolibrary.org/obo/IAO_0000088	report	http://purl.obolibrary.org/obo/IAO_0000310	document		A document assembled by an author for the purpose of providing information for the audience. A report is the output of a documenting process and has the objective to be consumed by a specific audience. Topic of the report is on something that has completed. A report is not a single figure. Examples of reports are journal article, patent application, grant progress report, case report (not patient record).
http://purl.obolibrary.org/obo/IAO_0000098	data format specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A data format specification is the information content borne by the document published defining the specification.
Example: The ISO document specifying what encompasses an XML document; The instructions in a XSD file
http://purl.obolibrary.org/obo/IAO_0000100	data set	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is an aggregate of other data items of the same type that have something in common. Averages and distributions can be determined for data sets.
http://purl.obolibrary.org/obo/IAO_0000101	image	http://purl.obolibrary.org/obo/IAO_0000308	figure		An image is an affine projection to a two dimensional surface, of measurements of some quality of an entity or entities repeated at regular intervals across a spatial range, where the measurements are represented as color and luminosity on the projected on surface.
http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part	http://purl.obolibrary.org/obo/IAO_0000027	data item		Data about an ontology part is a data item about a part of an ontology, for example a term
http://purl.obolibrary.org/obo/IAO_0000104	plan specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		A directive information entity with action specifications and objective specifications as parts, and that may be concretized as a realizable entity that, if realized, is realized in a process in which the bearer tries to achieve the objectives by taking the actions specified.
http://purl.obolibrary.org/obo/IAO_0000109	measurement datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A measurement datum is an information content entity that is a recording of the output of a measurement such as produced by a device.
http://purl.obolibrary.org/obo/IAO_0000144	conclusion textual entity	http://purl.obolibrary.org/obo/OBI_0001909	conclusion based on data		A textual entity that expresses the results of reasoning about a problem, for instance as typically found towards the end of scientific papers.
http://purl.obolibrary.org/obo/IAO_0000178	material information bearer	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity in which a concretization of an information content entity inheres.
http://purl.obolibrary.org/obo/IAO_0000179	histogram	http://purl.obolibrary.org/obo/IAO_0000038	graph		A histogram is a report graph which is a statistical description of a
distribution in terms of occurrence frequencies of different event classes.
http://purl.obolibrary.org/obo/IAO_0000180	heatmap	http://purl.obolibrary.org/obo/IAO_0000038	graph		A heatmap is a report graph which is a graphical representation of data
where the values taken by a variable(s) are shown as colors in a
two-dimensional map.
http://purl.obolibrary.org/obo/IAO_0000183	dendrogram	http://purl.obolibrary.org/obo/IAO_0000038	graph		A dendrogram is a report graph which is a tree diagram
frequently used to illustrate the arrangement of the clusters produced by a
clustering algorithm.
http://purl.obolibrary.org/obo/IAO_0000184	scatter plot	http://purl.obolibrary.org/obo/IAO_0000038	graph		A scatterplot is a graph which uses Cartesian coordinates to display values for two variables for a set of data. The data is displayed as a collection of points, each having the value of one variable determining the position on the horizontal axis and the value of the other variable determining the position on the vertical axis.
http://purl.obolibrary.org/obo/IAO_0000225	obsolescence reason specification	http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part		The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value.
http://purl.obolibrary.org/obo/IAO_0000300	textual entity	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A textual entity is a part of a manifestation (FRBR sense), a generically dependent continuant whose concretizations are patterns of glyphs intended to be interpreted as words, formulas, etc.
http://purl.obolibrary.org/obo/IAO_0000306	table	http://purl.obolibrary.org/obo/IAO_0000300	textual entity		A textual entity that contains a two-dimensional arrangement of texts repeated at regular intervals across a spatial range, such that the spatial relationships among the constituent texts expresses propositions
http://purl.obolibrary.org/obo/IAO_0000308	figure	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity consisting of a two dimensional arrangement of information content entities such that the arrangement itself is about something.
http://purl.obolibrary.org/obo/IAO_0000310	document	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A collection of information content entities intended to be understood together as a whole
http://purl.obolibrary.org/obo/IAO_0000311	publication	http://purl.obolibrary.org/obo/IAO_0000310	document		A document that is the output of a publishing process.
http://purl.obolibrary.org/obo/IAO_0000312	publication about an investigation	http://purl.obolibrary.org/obo/IAO_0000311	publication		A publication that is about an investigation
http://purl.obolibrary.org/obo/IAO_0000401	one dimensional cartesian spatial coordinate datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A cartesion spatial coordinate datum that  uses one value to specify a position along a one dimensional spatial region
http://purl.obolibrary.org/obo/IAO_0000408	length measurement datum	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		A scalar measurement datum that is the result of measurement of length quality
http://purl.obolibrary.org/obo/IAO_0000409	denotator type	http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part		A denotator type indicates how a term should be interpreted from an ontological perspective.
http://purl.obolibrary.org/obo/IAO_0000414	mass measurement datum	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		A scalar measurement datum that is the result of measurement of mass quality
http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		A scalar measurement datum that is the result of measuring a temporal interval
http://purl.obolibrary.org/obo/IAO_0000422	postal address	http://purl.obolibrary.org/obo/IAO_0000300	textual entity		A textual entity that is used as directive to deliver something to a person, or organization
http://purl.obolibrary.org/obo/IAO_0000572	documenting	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which a document is created or added to by including the specified input in it.
http://purl.obolibrary.org/obo/IAO_0000573	line graph	http://purl.obolibrary.org/obo/IAO_0000038	graph		A line graph is a type of graph created by connecting a series of data
points together with a line.
http://purl.obolibrary.org/obo/IAO_0000574	assigning a centrally registered identifier	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which a new CRID is created, associated with an entity, and stored in the CRID registry thereby registering it as being associated with some entity
http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol	http://purl.obolibrary.org/obo/IAO_0000028	symbol		A symbol that is part of a CRID and that is sufficient to look up a record from the CRID's registry.
http://purl.obolibrary.org/obo/IAO_0000579	centrally registered identifier registry	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process.
http://purl.obolibrary.org/obo/IAO_0000594	software application	http://purl.obolibrary.org/obo/IAO_0000010	software		A software application is software that can be directly executed by some processing unit.
http://purl.obolibrary.org/obo/IDO_0000586	infection	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A part of an extended organism that itself has as part a population of one or more infectious agents and that (1) exists as a result of processes initiated by members of the infectious agent population and is (2) clinically abnormal in virtue of the presence of this infectious agent population, or (3) has a disposition to bring clinical abnormality to immunocompetent organisms of the same Species as the host (the organism corresponding to the extended organism) through transmission of a member or offspring of a member of the infectious agent population.
http://purl.obolibrary.org/obo/IDO_0000666	human pathogenicity disposition	http://purl.obolibrary.org/obo/IDO_0000450	pathogenic disposition		A disposition to initiate processes that result in a disorder in a human organism.
http://purl.obolibrary.org/obo/OBI_0000006	role of being consumer safety officer	http://purl.obolibrary.org/obo/OBI_0000273	role of regulator of consumables and medical devices		the role of a human being that is realized by enforcing regulations to ensure consumer safety
http://purl.obolibrary.org/obo/OBI_0000010	fluorescent reporter intensity	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum that represents the output of a scanner measuring the intensity value for each fluorescent reporter.
http://purl.obolibrary.org/obo/OBI_0000011	planned process	http://purl.obolibrary.org/obo/BFO_0000015	process		A process that realizes a plan which is the concretization of a plan specification.
http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		Biological_feature_identification_objective is an objective role carried out by the proposition defining the aim of a study designed to examine or characterize a particular biological feature.
http://purl.obolibrary.org/obo/OBI_0000016	regulation-assigned role	http://purl.obolibrary.org/obo/OBI_0000017	regulatory role		Regulation-assigned role is a regulatory role defined by legislation or governmental orders
http://purl.obolibrary.org/obo/OBI_0000017	regulatory role	http://purl.obolibrary.org/obo/BFO_0000023	role		a role which inheres in material entities and is realized in the processes of making, enforcing or being defined by legislation or orders issued by a governmental body.
http://purl.obolibrary.org/obo/OBI_0000021	list-mode data file	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A list-mode data file is a binary digital entity where events are stored sequentially, parameter by parameter.
http://purl.obolibrary.org/obo/OBI_0000029	centrifuge pellet role	http://purl.obolibrary.org/obo/BFO_0000023	role		pellet role is a role which inheres in a material entity and is realized by a material separation process using gravitational force generated by a centrifuge in which the material bearing the pellet role is the heavier or heaviest component of the output material..
http://purl.obolibrary.org/obo/OBI_0000034	supernatant role	http://purl.obolibrary.org/obo/BFO_0000023	role		supernatant role is a role which inheres in a material entity and is realized by a material separation process using gravitational force in which the material bearing the supernatant role is the liquid component of the output material.
http://purl.obolibrary.org/obo/OBI_0000038	chromatography column	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		Chromatography column in chemistry is a tube and contents (typically glass) used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms.
http://purl.obolibrary.org/obo/OBI_0000041	pump valve switch	http://purl.obolibrary.org/obo/OBI_0000968	device		A pump valve switch is a cardinal part of a liquid chromatography instrument that controls the flow.
http://purl.obolibrary.org/obo/OBI_0000043	xenotransplantation	http://purl.obolibrary.org/obo/OBI_0000105	transplantation		is the transplantation of living cells, tissues or \norgans from one species to another such as from pigs to humans
http://purl.obolibrary.org/obo/OBI_0000044	physical document	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A physical document is an object serving as a record of information by means of symbolic marks.
http://purl.obolibrary.org/obo/OBI_0000045	waiting	http://purl.obolibrary.org/obo/OBI_0600009	exposure of material to environment		A planned process where an agent does not take any new actions towards a particular objective for a period of time until a set of conditions is met.
http://purl.obolibrary.org/obo/OBI_0000047	processed material	http://purl.obolibrary.org/obo/BFO_0000040	material entity		Is a material entity that is created or changed during material processing.
http://purl.obolibrary.org/obo/OBI_0000049	mass spectrometer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A mass spectrometer is an instrument which is used to measure the mass to charge ratio of ions. All mass spectrometers consist of three basic parts: an ion source, a mass analyzer, and a detector system. The stages within the mass spectrometer are: 1. Production of ions from the sample 2. Separation of ions with different masses 3. Detection of the number of ions of each mass produced 4.Collection of data to generate the mass spectrum
http://purl.obolibrary.org/obo/OBI_0000050	obsolete_platform	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A platform is an object_aggregate that is the set of instruments and software needed to perform a process. definition_source: OBI.
http://purl.obolibrary.org/obo/OBI_0000051	liquid chromatography mass spectrometry platform	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A liquid chromatography mass spectrometry platform is a platform that is the collection of instrument, software and reagents needed to perform a liquid chromatography mass spectrometry protocol. definition_source: OBI.
http://purl.obolibrary.org/obo/OBI_0000052	microarray platform	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A microarray platform is a platform that contains the instruments, software and reagents needed to perform a microarray protocol. definition_source: OBI.
http://purl.obolibrary.org/obo/OBI_0000054	ratio of collected to emitted light	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum measuring the amount of light collected s compared to the total amount of emitted light in the detector component of a flow cytometer instrument. The datum has a qualitative role
http://purl.obolibrary.org/obo/OBI_0000055	software optimization objective	http://purl.obolibrary.org/obo/OBI_0000242	software testing objective		Software_optimization is a software_testing_objective role describing a study designed to identify the best software or parameters of the software.
http://purl.obolibrary.org/obo/OBI_0000057	allotransplantation	http://purl.obolibrary.org/obo/OBI_0000105	transplantation		is the transplantation of organs between members of the same species.
http://purl.obolibrary.org/obo/OBI_0000059	gamma counter	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A processed material which measures gamma radiation
http://purl.obolibrary.org/obo/OBI_0000065	polyethylene glycol p-(1,1,3,3-tetramethylbutyl)-phenyl ether	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		triton X100 is a chemical entity which belongs to the group of The pluronics which are triblock copolymers of ethylene oxide and propylene oxide. Triton x-100 is_used_as detergent due to its non-ionic surfactant properties
http://purl.obolibrary.org/obo/OBI_0000066	investigation	http://purl.obolibrary.org/obo/OBI_0000011	planned process		a planned process that consists of parts: planning, study design execution, documentation and which produce conclusion(s).
http://purl.obolibrary.org/obo/OBI_0000067	evaluant role	http://purl.obolibrary.org/obo/BFO_0000023	role		a role that inheres in a material entity that is realized in an assay in which data is generated about the bearer of the evaluant role
http://purl.obolibrary.org/obo/OBI_0000071	quantitative confidence value	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item which is used to indicate the degree of uncertainty about a measurement.
http://purl.obolibrary.org/obo/OBI_0000075	diagnosis textual entity	http://purl.obolibrary.org/obo/IAO_0000300	textual entity		diagnosis is an assessment of a disease or injury, its likely prognosis and treatment.
http://purl.obolibrary.org/obo/OBI_0000076	unplanned occurrence effecting an investigation	http://purl.obolibrary.org/obo/BFO_0000015	process		a process which is external in origin to the investigation that has an impact on the outcome.
http://purl.obolibrary.org/obo/OBI_0000078	eMedical record	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An eMedical record is a digital document derived from a computer system used primarily for patient care in a clinical setting.  Not required to be compliant with requirements of 21 CFR Part 11.
http://purl.obolibrary.org/obo/OBI_0000079	culture medium	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a processed material that provides the needed nourishment for microorganisms or cells grown in vitro.
http://purl.obolibrary.org/obo/OBI_0000083	electronic case report tabulation	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An electronic case report tabulation is a digital document containing tabular data about multiple trial participants which is part of a clinical regulatory submission.  An eCRT has the property that it can be audited and compliant with requirements of 21 CFR Part 11  and has format suited to review by regulators.
http://purl.obolibrary.org/obo/OBI_0000084	polystyrene tube	http://purl.obolibrary.org/obo/OBI_0000836	test tube		A polystyrene tube is a test tube made of polystyrene
http://purl.obolibrary.org/obo/OBI_0000091	detector reagent role	http://purl.obolibrary.org/obo/BFO_0000023	role		a role which inheres in a molecular entity and is realized by the process of recording or registering a stimulus.
http://purl.obolibrary.org/obo/OBI_0000096	protocol testing objective	http://purl.obolibrary.org/obo/OBI_0000208	methodology testing objective		Protocol_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different protocols.
http://purl.obolibrary.org/obo/OBI_0000097	participant under investigation role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role that is realized through the execution of a study design in which the bearer of the role participates and in which data about that bearer is collected.
http://purl.obolibrary.org/obo/OBI_0000100	obsolete_role of being first subject treated	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		First subject treated role is a study subject role borne by the subject realized in the application of the process specified in intervention study design with no previous study subject realizing the role prior in the study
http://purl.obolibrary.org/obo/OBI_0000101	measured expression level	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum that is the outcome of the quantification of an assay for the activity of a gene, or the number of RNA transcripts.
http://purl.obolibrary.org/obo/OBI_0000105	transplantation	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a protocol application to replace an organ or tissue of an organism
http://purl.obolibrary.org/obo/OBI_0000109	obsolete biological vector role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a biological vector role is a material to be added role that is realized by the process of transmitting material to the organism that is the target of the transmission.
http://purl.obolibrary.org/obo/OBI_0000112	specimen role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen.
http://purl.obolibrary.org/obo/OBI_0000113	sequence feature identification objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		Sequence_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features exhibited at the level of a macromolecular sequence, e.g. nucleic acid, protein, polysaccharide.
http://purl.obolibrary.org/obo/OBI_0000115	intervention design	http://purl.obolibrary.org/obo/OBI_0500000	study design		An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays.
http://purl.obolibrary.org/obo/OBI_0000117	Bernoulli trial	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay where the output data is a datum with one of two values denoting success and failure.
http://purl.obolibrary.org/obo/OBI_0000118	gene list	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set of the names or identifiers of genes that are the outcome of an analysis or have been put together for the purpose of an analysis.
http://purl.obolibrary.org/obo/OBI_0000119	number of particles in subset	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum measuring the number of subjects in a defined subset in a flow cytometer instrument. The datum has a qualitative role
http://purl.obolibrary.org/obo/OBI_0000125	number of lost events electronic	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum measuring the number of analysis events lost due to errors in data acquisition electronic coincidence in a flow cytometer instrument. The datum has a qualitative role.
http://purl.obolibrary.org/obo/OBI_0000129	calibration substance role	http://purl.obolibrary.org/obo/OBI_0000025	reference substance role		A reference substance role that is realized when characteristics or responses elicited by the bearer are used to ensure an instrument is within protocol specification of accuracy or performance
http://purl.obolibrary.org/obo/OBI_0000131	molecular feature identification objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		Molecular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize molecular features of a biological system, e.g. expression profiling, copy number of molecular components, epigenetic modifications.
http://purl.obolibrary.org/obo/OBI_0000134	hardware testing objective	http://purl.obolibrary.org/obo/OBI_0000208	methodology testing objective		Hardware_testing_objective is a methodology_testing_objective role describing a study designed to examine the effects of using different hardware, e.g. scanner.
http://purl.obolibrary.org/obo/OBI_0000136	incubator	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device in which environmental conditions (light, photoperiod, temperature, humidity, etc.) can be controlled
http://purl.obolibrary.org/obo/OBI_0000146	supernatant collection system harvesting frame	http://purl.obolibrary.org/obo/OBI_0000967	container		A device that is designed for collecting 90% of the supernatant in a microplate well and separating the living cell with no stress, eliminating centrifugation and other similar techniques. It can be used in a variety of release assays with different radioactive isotopes, such as Cr51 or I125.
http://purl.obolibrary.org/obo/OBI_0000151	filter paper	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A device manufacture with the intent to provide a porous unsized paper used for filtering.
http://purl.obolibrary.org/obo/OBI_0000153	cell co-culturing	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A material combination in which cell cultures of two or more different types are are combined and allowed to culture as one.
http://purl.obolibrary.org/obo/OBI_0000158	eSource document	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		an eSource document is a digital document consisting of a logical collection of Source data and other eSource documents that can be presented in an ordered way and capture the time of completion, change, and any signatures
http://purl.obolibrary.org/obo/OBI_0000164	clonal cDNA library	http://purl.obolibrary.org/obo/OBI_0000731	recombinant vector		Mixed population of cDNAs (complementaryDNA) made from mRNA from a defined source, usually a specific cell type. This term should be associated only to nucleic acid interactors not to their proteins product. For instance in 2h screening use living cells (MI:0349) as sample process.

ALT DEF (PRS):: a cDNA library is a collection of host cells, typically E.Coli cells but not exclusively. modified by transfer of plasmid DNA molecule used as vector containing a fragment or totality of cDNA molecule (the insert) .  cDNA library may have an array of role and applications.
http://purl.obolibrary.org/obo/OBI_0000167	electronic case report form	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An electronic case report form is a digital document used to record all of the protocol required information to be reported for each trial subject. An eCRF has the property that it can be audited and compliant with requirements of 21 CFR Part 11.
http://purl.obolibrary.org/obo/OBI_0000171	autotransplantation	http://purl.obolibrary.org/obo/OBI_0000105	transplantation		is the transplantation of tissue from one part of \nthe body to another in the same individual. )
http://purl.obolibrary.org/obo/OBI_0000172	parameter threshold	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum measuring the minimal signal that must be detected to generate an electrical event, as compared to the maximal detected signal in a flow cytometer instrument. The datum has a qualitative role
http://purl.obolibrary.org/obo/OBI_0000175	p-value	http://purl.obolibrary.org/obo/OBI_0000071	quantitative confidence value		A quantitative confidence value that represents the probability of obtaining a result at least as extreme as that actually obtained, assuming that the actual value was the result of chance alone.
http://purl.obolibrary.org/obo/OBI_0000181	population	http://purl.obolibrary.org/obo/BFO_0000040	material entity		a population is a collection of individuals from the same taxonomic class living, counted or sampled at a particular site or in a particular area
http://purl.obolibrary.org/obo/OBI_0000182	NMR 3D molecular structure determination assay	http://purl.obolibrary.org/obo/OBI_0003117	3D molecular structure determination assay		A 3D molecular structure determination assay that uses magnetic properties of atomic nuclei to determine the 3D structure and dynamics of molecules in the input sample.
http://purl.obolibrary.org/obo/OBI_0000185	imaging assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that produces a picture of an entity.
http://purl.obolibrary.org/obo/OBI_0000186	protocol optimization objective	http://purl.obolibrary.org/obo/OBI_0000096	protocol testing objective		Protocol_optimization is a protocol_testing_objective role describing a study designed to identify the best protocol.  This may be carried out by comparing different protocols or by modifying the parameters used within a single protocol.
http://purl.obolibrary.org/obo/OBI_0000201	radioactivity detection	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the amount of radiation in the radioactive spectrum (alpha, beta or gamma rays) emitted from an input material.
http://purl.obolibrary.org/obo/OBI_0000205	obsolete_dropout role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		Dropout is a study subject role borne by an entity realized by a process of leaving the study earlier than the protocol specified and where the bearer of the dropout role had been borne study subject role prior to bearing dropout role.
http://purl.obolibrary.org/obo/OBI_0000208	methodology testing objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		Methodology_testing_objective is an objective role carried out by a proposition defining the aim of the study is to examine the effect of using different methodologies.
http://purl.obolibrary.org/obo/OBI_0000210	analytical cytology data file	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A digital entity intended to capture data in analytical cytology domain.
http://purl.obolibrary.org/obo/OBI_0000213	fluorescence compensation matrix	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A fluorescence compensation matrix is a square matrix which is used as the left multiplier of the vector of fluorescence values while performing digital fluorescence compensation. Also, fluorescence compensation matrix is the inverse of the fluorescence spillover matrix.
http://purl.obolibrary.org/obo/OBI_0000218	investigation results report	http://purl.obolibrary.org/obo/IAO_0000088	report		An investigation report is a report on the results of an investigation.
http://purl.obolibrary.org/obo/OBI_0000219	cellular feature identification objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		Cellular_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the cellular level, e.g. stage of cell cycle, stage of differentiation.
http://purl.obolibrary.org/obo/OBI_0000223	obsolete_blinded medication role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		Is a role which inheres in a material entity which is manufactured to be similar in appearance to a test material entity in e.g. a clinical trial to prevent participants from detecting which is the active and inactive substance
http://purl.obolibrary.org/obo/OBI_0000227	data encoding	http://purl.obolibrary.org/obo/IAO_0000572	documenting		a documenting process to encode an information entity into a digital document
http://purl.obolibrary.org/obo/OBI_0000231	enzymatic cleavage	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a material processing that digests the fraction of input material that is susceptible to that enzyme
http://purl.obolibrary.org/obo/OBI_0000232	hardware optimization objective	http://purl.obolibrary.org/obo/OBI_0000134	hardware testing objective		Hardware_optimization is a hardware_testing_objective describing a study designed to identify the best hardware.
http://purl.obolibrary.org/obo/OBI_0000233	obsolete_defined_material	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		Place holder class, Utility class to gather the defined classes
http://purl.obolibrary.org/obo/OBI_0000235	standard error	http://purl.obolibrary.org/obo/OBI_0000071	quantitative confidence value		A quantitative confidence value which is the standard deviations of the sample in a frequency distribution, obtained by dividing the standard deviation by the total number of cases in the frequency distribution.
http://purl.obolibrary.org/obo/OBI_0000237	antigen role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role of a material entity that is being recognized in whole or in part by receptors of the immune system such as antibodies or T cell receptors.
http://purl.obolibrary.org/obo/OBI_0000242	software testing objective	http://purl.obolibrary.org/obo/OBI_0000208	methodology testing objective		Software_testing_objective is a hardware_optimization role describing a study designed to examine the effects of using different software or software parameters, e.g. data processing software.
http://purl.obolibrary.org/obo/OBI_0000245	organization	http://purl.obolibrary.org/obo/BFO_0000040	material entity		An entity that can bear roles, has members, and has a set of organization rules. Members of organizations are either organizations themselves or individual people. Members can bear specific organization member roles that are determined in the organization rules. The organization rules also determine how decisions are made on behalf of the organization by the organization members.
http://purl.obolibrary.org/obo/OBI_0000251	cluster	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set which is a subset of data that are a similar to each other in some way.
http://purl.obolibrary.org/obo/OBI_0000252	cohort role	http://purl.obolibrary.org/obo/OBI_0000198	biological replicate role		a cohort role is a biological replicate role played by a group of study participants who share a common characteristic of interest to the study.
http://purl.obolibrary.org/obo/OBI_0000253	artificially induced nucleic acid hybridization	http://purl.obolibrary.org/obo/OBI_0000094	material processing		Is a material transformation in which strands of nucleic acids that are (somewhat) complementary form a double-stranded molecule. Has input at least two single stranded molecules of nucleic acid molecules.
http://purl.obolibrary.org/obo/OBI_0000257	DNA extraction	http://purl.obolibrary.org/obo/OBI_0666667	nucleic acid extraction		A DNA extraction is a nucleic acid extraction where the desired output material is DNA.
http://purl.obolibrary.org/obo/OBI_0000260	plan	http://purl.obolibrary.org/obo/BFO_0000017	realizable entity		A plan is a realizable entity that is the inheres in a bearer who is committed to realizing it as a planned process.
http://purl.obolibrary.org/obo/OBI_0000268	organism feature identification objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		Organism_feature_identification_objective is a biological_feature_identification_objective role describing a study designed to examine or characterize a biological feature monitored at the level of the organism, e.g. height, weight, stage of development, stage of life cycle.
http://purl.obolibrary.org/obo/OBI_0000269	number of lost events computer	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum recording the number of measurement events lost due to overloading of the analysis chip in a flow cytometer instrument. The datum has a qualitative role
http://purl.obolibrary.org/obo/OBI_0000272	protocol	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which has sufficient level of detail and quantitative information to communicate it between investigation agents, so that different investigation agents will reliably be able to independently reproduce the process.
http://purl.obolibrary.org/obo/OBI_0000274	adding a material entity into a target	http://purl.obolibrary.org/obo/OBI_0000652	material combination		is a process with the objective to place a material entity bearing the 'material to be added role' into a material bearing the 'target of material addition role'.
http://purl.obolibrary.org/obo/OBI_0000275	analyte role	http://purl.obolibrary.org/obo/OBI_0002444	measurand role		A measurand role borne by a molecular entity or an atom and realized in an analyte assay which achieves the objective to measure the magnitude/concentration/amount of the analyte in the entity bearing evaluant role.
http://purl.obolibrary.org/obo/OBI_0000278	disease stage	http://purl.obolibrary.org/obo/GO_0008150	biological process		a part of an occurrence of a disease process which is associated with position in the normal progression of the disease
http://purl.obolibrary.org/obo/OBI_0000281	intraperitoneal injection	http://purl.obolibrary.org/obo/OBI_0000429	intraperitoneal administration		is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe
http://purl.obolibrary.org/obo/OBI_0000288	protein-protein interaction detection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that determines interactions between proteins, such as protein-protein binding.
http://purl.obolibrary.org/obo/OBI_0000296	obsolete_enrollment	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		enrollment is a process of identifying a set of objects for further use in an investigation based on a set of criteria or rules
http://purl.obolibrary.org/obo/OBI_0000310	adverse event trigger	http://purl.obolibrary.org/obo/IAO_0000001	conditional specification		revisit?
http://purl.obolibrary.org/obo/OBI_0000319	material to be added role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role of a material entity that is realized in an "adding a material entity into a target" process where the bearer of the role is added into another material entity (the target).
http://purl.obolibrary.org/obo/OBI_0000323	obsolete_peritoneum	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		is the serous membrane that forms the lining of the abdominal cavity
http://purl.obolibrary.org/obo/OBI_0000338	drawing a conclusion based on data	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which data gathered in an investigation is evaluated in the context of existing knowledge with the objective to generate more general conclusions or to conclude that the data does not allow one to draw general conclusion
http://purl.obolibrary.org/obo/OBI_0000339	planning	http://purl.obolibrary.org/obo/BFO_0000015	process		a process of creating or modifying a plan specification
http://purl.obolibrary.org/obo/OBI_0000341	histological sample preparation	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process		histological sample preparation is the preparation of an input tissue via slicing and labeling to make tissue microstructure of interest visible in a future histology assay
http://purl.obolibrary.org/obo/OBI_0000343	inductive reasoning	http://purl.obolibrary.org/obo/OBI_0000338	drawing a conclusion based on data		a interpreting data that is used to ascribe properties or relations to types based on an observation instance (i.e., on a number of observations or experiences); or to formulate laws based on limited observations of recurring phenomenal patterns.
http://purl.obolibrary.org/obo/OBI_0000345	mass analyzer	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A Mass analyzer is a device that separates ions according to their mass-to-charge ratio. All mass spectrometers are based on dynamics of charged particles in electric and magnetic fields in vacuum where the two laws of Lorentz force law and Newton's second law of motion apply.
http://purl.obolibrary.org/obo/OBI_0000355	hypothesis-driven investigation	http://purl.obolibrary.org/obo/OBI_0000066	investigation		is an investigation with the goal to test one or more hypothesis
http://purl.obolibrary.org/obo/OBI_0000356	hypothesis generating investigation	http://purl.obolibrary.org/obo/OBI_0000066	investigation		is an investigation in which data is generated and analyzed with the purpose of generating new hypothesis
http://purl.obolibrary.org/obo/OBI_0000361	ion source	http://purl.obolibrary.org/obo/OBI_0000968	device		An ion source is a device that is part of a mass spectrometer that ionizes the material under analysis. The ions are then transported by magnetic or electric fields to the mass analyzer.  Techniques for ionization have been key to determining what types of samples can be analyzed by mass spectrometry. Electron ionization and chemical ionization are used for gases and vapors. In chemical ionization sources, the material is ionized by chemical ion-molecule reactions during collisions in the source. Two techniques often used with liquid and solid biological samples include electrospray ionization (due to John Fenn PMID 2675315.) and matrix-assisted laser desorption/ionization (MALDI, due to M. Karas and F. Hillenkamp (Measuring Mass: From Positive Rays to Proteins by Michael A. Grayson (Editor) (ISBN 0-941901-31-9))).
http://purl.obolibrary.org/obo/OBI_0000364	ion detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		An ion detector is a device that measures and records the charge induced or current produced when an ion passes by or hits a surface.  Example: In a scanning instrument the signal produced in the detector during the course of the scan versus where the instrument is in the scan (at what m/Q) will produce a mass spectrum, a record of ions as a function of m/Q.
http://purl.obolibrary.org/obo/OBI_0000367	light emission function	http://purl.obolibrary.org/obo/OBI_0000374	excitation function		A light emission function is an excitation function to excite a material to a specific excitation state that it emits light.
http://purl.obolibrary.org/obo/OBI_0000368	record function	http://purl.obolibrary.org/obo/BFO_0000034	function		A record function is a function that registers or collects information in a particular format on a particular recording medium. For example on paper or a digital representation
http://purl.obolibrary.org/obo/OBI_0000369	magnify function	http://purl.obolibrary.org/obo/BFO_0000034	function		A magnify function is a function to increase the size of a transmitted object image through the precise arrangement of energy diffraction elements along an imaging path.
http://purl.obolibrary.org/obo/OBI_0000370	contain function	http://purl.obolibrary.org/obo/BFO_0000034	function		A contain function is a function to constrain a material entities location in space
http://purl.obolibrary.org/obo/OBI_0000371	heat function	http://purl.obolibrary.org/obo/BFO_0000034	function		A heat function is a function that increases the internal kinetic energy of a material
http://purl.obolibrary.org/obo/OBI_0000372	material separation function	http://purl.obolibrary.org/obo/BFO_0000034	function		A material separation function is a function that increases the resolution between two or more material entities. The  to distinction between the entities is usually based on some associated physical quality.
http://purl.obolibrary.org/obo/OBI_0000373	ionize process	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a physical process of converting an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions. This excludes chemical processes of dissociation.
http://purl.obolibrary.org/obo/OBI_0000374	excitation function	http://purl.obolibrary.org/obo/BFO_0000034	function		A excitation function is a function  to inject energy by bombarding a material with energetic particles (e.g., photons) thereby imbuing internal material components such as electrons with additional energy.  These internal, 'excited' particles may lead to the rupturing of covalent chemical bonds or may quickly relax back to there unexcited state with an exponential time course thereby locally emitting energy in the form of photons.
http://purl.obolibrary.org/obo/OBI_0000375	freeze function	http://purl.obolibrary.org/obo/BFO_0000034	function		A freeze function is a function to decrease the internal kinetic energy of a material below the freezing point of that type of material.
http://purl.obolibrary.org/obo/OBI_0000376	synthesizing function	http://purl.obolibrary.org/obo/BFO_0000034	function		A synthesizing function is a function to assemble new output materials from distinct input materials.  The output materials typically consist of chemically distinct monomeric objects or object aggregate polymers.
http://purl.obolibrary.org/obo/OBI_0000377	perturb function	http://purl.obolibrary.org/obo/BFO_0000034	function		A perturb function is a function that disrupts the normal function of a system induced through either internal or external means.  External means of perturbation include: (1) displacement fields in the physical sense - e.g., temperature change, osmotic shock, pressure change; (2) application of small molecules such as drugs or toxins to perturb the function of specific pathways or application of surfactants to perturb the normal function of plasma membrane.  Internal means of perturbation include: (1) manipulation of gene function via gene knockout or transcript knockdown via RNAi; (2) directed genetic mutation leading to minimal aa alterations that interfere with peptide function.
http://purl.obolibrary.org/obo/OBI_0000378	filter function	http://purl.obolibrary.org/obo/OBI_0000372	material separation function		A filter function is a function to prevent the flow of certain entities based on a quality or qualities of the entity while allowing entities which have different qualities to pass through
http://purl.obolibrary.org/obo/OBI_0000379	mechanical function	http://purl.obolibrary.org/obo/BFO_0000034	function		A mechanical function is a function that is realised via mechanical work (through an certain amount of energy transferred by some force).
http://purl.obolibrary.org/obo/OBI_0000380	gas filter function	http://purl.obolibrary.org/obo/OBI_0000378	filter function		A gas filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a gas-solid mixture
http://purl.obolibrary.org/obo/OBI_0000381	liquid filter function	http://purl.obolibrary.org/obo/OBI_0000378	filter function		A liquid filter function is a filter function which prevents the flow of solid objects, defined by specific qualities, in a liquid-solid mixture
http://purl.obolibrary.org/obo/OBI_0000383	transfer function	http://purl.obolibrary.org/obo/BFO_0000034	function		A transfer function is a function to displace a material from one location to another.
http://purl.obolibrary.org/obo/OBI_0000385	ionization function	http://purl.obolibrary.org/obo/BFO_0000034	function		An ionization function is a function to physically convert an atom or molecule into an ion by adding or removing charged particles such as electrons or other ions.
http://purl.obolibrary.org/obo/OBI_0000387	cool function	http://purl.obolibrary.org/obo/BFO_0000034	function		A cool function is a function to decrease the internal kinetic energy of a material below the initial kinetic energy of that type of material.
http://purl.obolibrary.org/obo/OBI_0000388	connection function	http://purl.obolibrary.org/obo/BFO_0000034	function		A connection function is a function to couple two or more flow channels so that material or signals can be transported from one set of channels to another.
http://purl.obolibrary.org/obo/OBI_0000390	thermostatic circulator	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		A thermostatic circulator is a device which cools or heats a circulating liquid. It has the function to contain control the contained environment and transfer energy from or to the circulating liquid
http://purl.obolibrary.org/obo/OBI_0000391	energy supply function	http://purl.obolibrary.org/obo/BFO_0000034	function		An energy supply function is a function to supply or transfer energy from an energy source to a consumer of the energy
http://purl.obolibrary.org/obo/OBI_0000394	blot module	http://purl.obolibrary.org/obo/OBI_0000968	device		A blot module is a device which has the function to conatin and facilitate the material transfer process blotting to be realised
http://purl.obolibrary.org/obo/OBI_0000395	signal amplification function	http://purl.obolibrary.org/obo/OBI_0000393	signal conversion function		A signal amplification function is a signal conversion function to inject energy into an input signal so as to produce an output signal with increased differential magnitude while also seeking to minimize increases in the signal to noise ratio. For example, to produce a 0.1 KW output signal from a 1 mW RMS input signal.
http://purl.obolibrary.org/obo/OBI_0000397	image acquisition function	http://purl.obolibrary.org/obo/OBI_0000453	measure function		An image acquisition function is a function to acquire an image of a material
http://purl.obolibrary.org/obo/OBI_0000399	solid support function	http://purl.obolibrary.org/obo/BFO_0000034	function		A solid support function is a function of a device on which an entity is kept in a defined position and prevented in its movement
http://purl.obolibrary.org/obo/OBI_0000400	display function	http://purl.obolibrary.org/obo/OBI_0000392	information processor function		A display function is a function to present information by translating that information through some lookup process into visual form.
http://purl.obolibrary.org/obo/OBI_0000401	environment control function	http://purl.obolibrary.org/obo/BFO_0000034	function		An environmental control function is a function that regulates a contained environment within specified parameter ranges. For example the control of light exposure, humidity and temperature.
http://purl.obolibrary.org/obo/OBI_0000403	sort function	http://purl.obolibrary.org/obo/OBI_0000372	material separation function		A sort function is a function to distinguish material components based on some associated physical quality or entity and to partition the separate components into distinct fractions according to a defined order.
http://purl.obolibrary.org/obo/OBI_0000404	gel dryer	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		A gel dryer is a device which has the function to contain and to control the contained environment to facilitate the drying of gels
http://purl.obolibrary.org/obo/OBI_0000405	primer role	http://purl.obolibrary.org/obo/OBI_0000857	complementary nucleotide probe role		a complementary nucleotide probe role which inheres in nucleic acid molecular entity and is realized by the use of the entity bearing the role to initiate chain elongation.
http://purl.obolibrary.org/obo/OBI_0000406	PCR product	http://purl.obolibrary.org/obo/CHEBI_4705	double-stranded DNA		is double stranded DNA that is the specified output of a polymerase chain reaction
http://purl.obolibrary.org/obo/OBI_0000407	viral RNA extraction	http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction		The extraction of RNA from an input material that specifically isolates viral RNA
http://purl.obolibrary.org/obo/OBI_0000409	nucleic acid template role	http://purl.obolibrary.org/obo/OBI_0000025	reference substance role		a reference substance role which inheres in nucleic acid material entity and is realized in the process of using the nucleic acid bearing the template role as a reference during synthesis of a reverse copy.
http://purl.obolibrary.org/obo/OBI_0000410	recombinant plasmid	http://purl.obolibrary.org/obo/OBI_0000731	recombinant vector		a plasmid in which extraneous DNA has been inserted.
http://purl.obolibrary.org/obo/OBI_0000411	cloning vector role	http://purl.obolibrary.org/obo/OBI_0000319	material to be added role		A material to be added role played by a small, self-replicating DNA or RNA molecule - usually a plasmid or chromosome - and realized in a process whereby foreign DNA or RNA is inserted into the vector during the process of cloning.
http://purl.obolibrary.org/obo/OBI_0000413	cell cycle synchronization	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a process with the objective to obtain a cell culture in which all cells are in the same stage of the cell cycle
http://purl.obolibrary.org/obo/OBI_0000416	cloning insert role	http://purl.obolibrary.org/obo/BFO_0000023	role		cloning insert role is a role which inheres in DNA or RNA and is realized by the process of being inserted into a cloning vector in a cloning process.
http://purl.obolibrary.org/obo/OBI_0000418	measuring glucose concentration in blood serum assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An assay that determines the concentration of glucose molecules in a blood serum sample
http://purl.obolibrary.org/obo/OBI_0000419	reverse transcriptase	http://purl.obolibrary.org/obo/OBI_0000427	enzyme		enzyme and has_function some GO:0003964 (RNA-directed DNA polymerase
activity)
http://purl.obolibrary.org/obo/OBI_0000420	obsolete_trypsinized material	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A material entity that has undergone a process of digestion with trypsin
http://purl.obolibrary.org/obo/OBI_0000422	syringe	http://purl.obolibrary.org/obo/OBI_0000968	device		A processed material which is used to introduce or draw fluids from a material entity. A syringe is made of a piston and body. the movement of the piston in the body determines the amount/volume of fluid to inject or draw
http://purl.obolibrary.org/obo/OBI_0000425	averaging objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		An averaging objective is a data transformation objective where the aim is to perform mean calculations on the input of the data transformation.
http://purl.obolibrary.org/obo/OBI_0000426	injection	http://purl.obolibrary.org/obo/OBI_0000274	adding a material entity into a target		injection is process which aims at introducing a compound or a mixture into a material entity (either biological entity or instrument) by relying on devices such as syringe or injector connection, attached or forced into a vascular system (veins of an organism or tubes of a machine) or in a tissue.
http://purl.obolibrary.org/obo/OBI_0000427	enzyme	http://purl.obolibrary.org/obo/BFO_0000040	material entity		(protein or rna) or has_part (protein or rna) and
has_function some GO:0003824 (catalytic activity)
http://purl.obolibrary.org/obo/OBI_0000429	intraperitoneal administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		The administration of a substance into the peritoneum of an organism
http://purl.obolibrary.org/obo/OBI_0000430	plasmid	http://purl.obolibrary.org/obo/CHEBI_4705	double-stranded DNA		plasmid = DNA and has_quality circular and has_function
(is_realized_as some gene expression) GO:0010467
http://purl.obolibrary.org/obo/OBI_0000431	injection into organ section	http://purl.obolibrary.org/obo/OBI_0000426	injection		A process in which an input substance is injected into a organ section.
http://purl.obolibrary.org/obo/OBI_0000432	polyacrylamide gel	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a material entity resulting from the polymerization of acrylamide with TEMED in some buffer solution
http://purl.obolibrary.org/obo/OBI_0000433	DNA sequence feature detection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay with the objective to determine a sequence feature of DNA
http://purl.obolibrary.org/obo/OBI_0000434	adding material objective	http://purl.obolibrary.org/obo/OBI_0000686	material combination objective		is the specification of an objective to add a material into a target material. The adding is asymmetric in the sense that the target material largely retains its identity
http://purl.obolibrary.org/obo/OBI_0000436	needle	http://purl.obolibrary.org/obo/OBI_0000968	device		A needle is a sharp, hollow device used to penetrate tissue or soft material. When attached to a syringe. it allows delivery of a specific volume of liquid or gaseous mixture.
http://purl.obolibrary.org/obo/OBI_0000437	analyte measurement objective	http://purl.obolibrary.org/obo/OBI_0000441	assay objective		an assay objective to determine the presence or concentration of an analyte in the evaluant
http://purl.obolibrary.org/obo/OBI_0000438	DNA sequence variation detection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures changes (expansion, amplification, deletion, mutation) in the sequence of a DNA molecule.
http://purl.obolibrary.org/obo/OBI_0000439	agarose gel	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a material entity resulting from the polymerization of agarose after heating agarose suspended in some buffer solution
http://purl.obolibrary.org/obo/OBI_0000441	assay objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		an objective specification to determine a specified type of information about an evaluated entity (the material entity bearing evaluant role)
http://purl.obolibrary.org/obo/OBI_0000442	obsolete_heart	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		The heart is a muscular organ found in all vertebrates that is responsible for pumping blood throughout the blood vessels by repeated, rhythmic contractions
http://purl.obolibrary.org/obo/OBI_0000443	analyte assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay with the objective to capture information about the presence, concentration, or amount of an analyte in an evaluant.
http://purl.obolibrary.org/obo/OBI_0000444	target of material addition role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role of a material entity that is realized in an "adding a material entity into a target" process where the bearer of the role (the target) receives the addition of another material entity.
http://purl.obolibrary.org/obo/OBI_0000445	mass measurement assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that determines the mass of an evaluant
http://purl.obolibrary.org/obo/OBI_0000446	obsolete_identification	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a process by which the identity (what a thing is) of a material entity is established within a certain confidence interval
http://purl.obolibrary.org/obo/OBI_0000447	intracellular electrophysiology recording assay	http://purl.obolibrary.org/obo/OBI_0002176	electrophysiology assay		An electrophysiology assay where the recording location of the electrode is intracellular.
http://purl.obolibrary.org/obo/OBI_0000448	packed column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A packed column is a chromatography column where the particles of the solid stationary phase or the support coated with a liquid stationary phase may fill the whole inside volume of the tube.
http://purl.obolibrary.org/obo/OBI_0000449	obsolete_defined_output	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		This is only a placeholder for defined classes, as are its siblings _defined_material and _defined protocol application. Its children should be defined classes constructed as output of a process.
http://purl.obolibrary.org/obo/OBI_0000450	regulatory agency	http://purl.obolibrary.org/obo/OBI_0000245	organization		A regulatory agency is a organization that has responsibility over or for  the legislation (acts and regulations) for a given sector of the government.
http://purl.obolibrary.org/obo/OBI_0000451	normalized data set	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set that is produced as the output of a normalization data transformation.
http://purl.obolibrary.org/obo/OBI_0000453	measure function	http://purl.obolibrary.org/obo/BFO_0000034	function		Measure function is a function that is borne by a processed material  and realized in a process in which information about some entity is expressed relative to some reference.
http://purl.obolibrary.org/obo/OBI_0000454	extracellular electrophysiology recording assay	http://purl.obolibrary.org/obo/OBI_0002176	electrophysiology assay		An electrophysiology assay where the recording location of the electrode is extracellular.
http://purl.obolibrary.org/obo/OBI_0000455	consume data function	http://purl.obolibrary.org/obo/BFO_0000034	function		Process data function is a function that is borne by in a material entity by virtue of its structure. When realized the material entity consumes data.
http://purl.obolibrary.org/obo/OBI_0000457	manufacturing	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A planned process with the objective to produce a processed material which will have a function for future use.
http://purl.obolibrary.org/obo/OBI_0000458	manufacturing objective	http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective		is the objective to manufacture a material of a certain function (device)
http://purl.obolibrary.org/obo/OBI_0000463	column chromatography detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		There is a wide range of detectors available for both GC and LC each having their own particular areas of application. In general the more catholic the response, the less sensitive the detector and the most sensitive detectors are those that have a specific response. The performance of all detectors should be properly specified so that the user can determine which is most suitable for a specific application. Such specifications are also essential to compare the performance of different detectors supplied by alternative instrument manufactures. Detector specifications should be presented in a standard form and in standard units, so that detectors can be compared that function on widely different principles.
http://purl.obolibrary.org/obo/OBI_0000464	Bruker autosampler	http://purl.obolibrary.org/obo/OBI_0000555	autosampler		A Bruker autosampler is an autosampler made by Bruker.
http://purl.obolibrary.org/obo/OBI_0000465	organic acid column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		An organic acid column is a chromatography column which enables (reversed-phase) separation of hydrophilic aliphatic and aromatic organic acids with UV detection. Organic acid columns allow retention of polar and apolar organic acids and are hydrolysis resistant.
http://purl.obolibrary.org/obo/OBI_0000467	Bruker US 2 NMR magnet	http://purl.obolibrary.org/obo/OBI_0000597	Bruker NMR magnet		An actively-shielded superconducting magnet from Bruker that combines Bruker BioSpin's advanced, proprietary UltraShield active shielding and UltraStabilized sub-cooling technologies. This shielded and stabilized (US2) magnet system delivers high sensitivity and spectral dispersion.
http://purl.obolibrary.org/obo/OBI_0000468	protein column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A protein column is a chromatography column used for the separation of complex protein mixtures. Protein columns enable sample desalting, followed by chromatographic separation or fractionation of complex protein samples, e.g. immunodepleted serum or plasma proteins.
http://purl.obolibrary.org/obo/OBI_0000469	solvent mixer	http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument		A liquid chromatography device that mixes different solvents, e.g. under high pressure and in differrent volumes ranging from 5 ml to 5 L capacity. Powerful magnetic mixers provide vigorous agitation required for high pressure reaction chemistry.
http://purl.obolibrary.org/obo/OBI_0000470	mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that identifies the amount and type of material entities present in a sample by fragmenting the sample and measuring the mass-to-charge ratio of the resulting particles.
http://purl.obolibrary.org/obo/OBI_0000471	study design execution	http://purl.obolibrary.org/obo/OBI_0000011	planned process		a planned process that carries out a study design
http://purl.obolibrary.org/obo/OBI_0000473	Bruker NMR Case sample changer	http://purl.obolibrary.org/obo/OBI_0000464	Bruker autosampler		The NMR Case is an economical NMR sample changer for laboratories with modest automation needs. It expands the maximum number of samples your spectrometer can process during unattended operation to 24. The NMR Case consists of multiple components. The NMR Case exchange module installed atop your cryostat. The two front legs are adjustable, making the NMR Case compatible with many different cryostats.
http://purl.obolibrary.org/obo/OBI_0000474	nano pump system	http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system		A pump system optimized for nano flow chromatography.
http://purl.obolibrary.org/obo/OBI_0000475	Bruker AutoClean system	http://purl.obolibrary.org/obo/OBI_0000498	NMR tube washing system		NMR tubes are often used once and discarded, creating needless waste. With the Bruker BioSpin Autoclean system you can now recycle 5mm, 3mm, or 5mm/3mm step-down (Wilmad 520-1B) NMR tubes. AutoClean NMR Tube Washing System is a simple way to recoup the substantial investment your organization makes in quality NMR tubes, and cut back on needless waste material.
http://purl.obolibrary.org/obo/OBI_0000476	manual injection system	http://purl.obolibrary.org/obo/OBI_0000504	sample injection system		The traditional hardware system that allows a human to inject a sample into an inlet by hand, using a syringe.
http://purl.obolibrary.org/obo/OBI_0000477	Varian GEMINI spectrometer	http://purl.obolibrary.org/obo/OBI_0000611	Varian NMR instrument		An older Varian Broadband NMR spectrometer.
http://purl.obolibrary.org/obo/OBI_0000478	column connector	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A device that connects two or more columns together in a functional way with leak-tight connection, low dead volume, low thermal mass and high inertness.
http://purl.obolibrary.org/obo/OBI_0000479	solid NMR probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe that is designed to hold a solid sample.
http://purl.obolibrary.org/obo/OBI_0000481	chromatography detector	http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument		A chromatography detector is a device that locates in the dimensions of space and time, the positions of the components of a mixture that has been subjected to a chromatographic process and thus permits the senses to appreciate the nature of the separation.  Defining characteristics are Dynamic Range, Response Index or Linearity, Linear Dynamic range, Detector Response,  Detector Noise Level, Detector Sensitivity or Minimum Detectable Concentration, Total System Dispersion, Sensor Dimensions, Detector Time Constant, Pressure Sensitivity, Flow Sensitivity, Operating Temperature Range.
http://purl.obolibrary.org/obo/OBI_0000482	normal phase column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A normal phase column is a chromatography column in which the stationary phase is more polar than the mobile phase. Its counterpart is the reversed phase column.
http://purl.obolibrary.org/obo/OBI_0000483	APOLLO console	http://purl.obolibrary.org/obo/OBI_0000599	tecmag NMR console		The APOLLO is a compact, modular, multiple-DSP, Windows XP Professional-based console that can be equipped with up to 8 DDS-based RF transmitter channels configurable from 2 kHz to 3.5 GHz. Each transmitter channel produces a nominal 1V output and has the most agile frequency, phase and amplitude control of any system on the market. An array of additional options are available including multiple RF transmitters, linear high-power RF amplifiers, digital receiver arrays, low noise figure preamplifiers, a gradient control system, shim unit, MAS spin-speed controller, variable temperature unit, digital lock system and probe/coil interface. With its numerous options, the Apollo can be configured for any NMR, NQR or MRI application.
http://purl.obolibrary.org/obo/OBI_0000484	NMR sample holder	http://purl.obolibrary.org/obo/OBI_0000968	device		An NMR sample holder is the part of an NMR instrument, which carries the NMR probe,sample tube and the nmr sample.
http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		Any instrument that is used to carry out a chromatography experiment.
http://purl.obolibrary.org/obo/OBI_0000486	continuous wave NMR instrument	http://purl.obolibrary.org/obo/OBI_0000566	NMR instrument		Continuous wave NMR spectrometers are similar to optical spectrometers, but the sample is held in a strong magnetic field, where the frequency of the source is slowly scanned (in some instruments, the source frequency is held constant, and the field is scanned).
http://purl.obolibrary.org/obo/OBI_0000487	fourier transformation NMR instrument	http://purl.obolibrary.org/obo/OBI_0000566	NMR instrument		In fourier transformation NMR, all frequencies in a spectrum are irradiated simultaneously with a radio frequency pulse. Following the pulse, the nuclei return to thermal equilibrium. A time domain emission signal is recorded by the instrument as the nuclei relax. A frequency domain spectrum is obtained by Fourier transformation.
http://purl.obolibrary.org/obo/OBI_0000489	nitrogen phosphorous detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector		The nitrogen phosphorus detector (NPD) (sometimes called the thermionic detector) is a very sensitive, specific detector the design of which, is based on the FID. Physically the sensor appears to be very similar to the FID but, in fact, operates on an entirely different principle. The nitrogen phosphorous detector (sometimes called the thermionic detector) is a very sensitive but specific detector that responds almost exclusively to nitrogen and phosphorous compounds. It is based on the flame ionization detector but differs in that it contains a rubidium or cesium silicate (glass) bead situated in a heater coil, a little distance from the hydrogen flame. If the detector is to respond to both nitrogen and phosphorous then the hydrogen flow should be minimal so that the gas does not ignite at the jet. If the detector is to respond to phosphorous only, a large flow of hydrogen is used which is burnt at the jet. The heated bead emits electrons by thermionic emission. These electrons are collected under a potential of a few volts by an appropriately placed anode, and provides a background current. When a solute containing nitrogen or phosphorous is eluted from the column, the partially combusted nitrogen and phosphorous materials are adsorbed on the surface of the bead. The adsorbed material reduces the work function of the surface and, as consequence, the emission of electrons is increased which raises the current collected at the electrode. The sensitivity of the detector to phosphorous is about 10-12 gram per ml and for nitrogen about 10-11 gram per ml at a signal to nose ratio of 2. The alkali bead as a finite life and needs regular replacement.
http://purl.obolibrary.org/obo/OBI_0000490	cation exchange column	http://purl.obolibrary.org/obo/OBI_0000560	ion exchange column		A cation exchange column is a chromatography column that is used in cation exchange chromatography.
http://purl.obolibrary.org/obo/OBI_0000491	direct detection NMR probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe designed to allow the direct detection of acquisition nuclei.
http://purl.obolibrary.org/obo/OBI_0000492	Bruker B-ACS system	http://purl.obolibrary.org/obo/OBI_0000464	Bruker autosampler		The Bruker Automatic Sample Changer (B-ACS 60/120), used in conjunction with Bruker DISNMR, UXNMR or XWIN-NMR software, provides dialog-guided facilities which allow the user to easily and effectively perform automatic (continuous) experiments. Features include a 60 or 120 sample capacity, random accessing of samples, positive sample identification with the optional bar code reader, and temperature control of individual samples with the optional sample heater unit.
http://purl.obolibrary.org/obo/OBI_0000493	rapid resolution column	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A rapid resolution column is a chromatography column as marketed by Agilent, which is used with a rapid resolution cartridge to ensure a fast chromatography process with good separation resolution.
http://purl.obolibrary.org/obo/OBI_0000494	liquid chromatography autosampler	http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument		Designed to perform capillary LC with injection of sample volumes ranging from nL to L.
http://purl.obolibrary.org/obo/OBI_0000495	vacuum degasser	http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system		A degassing system used for degassing solvents in liquid chromatography. Dissolved gasses, usually nitrogen and oxygen from the air, tend to be evolved in the mobile phase as the pressure is reduced when the mobile phase leaves the liquid chromatography column and enters the detector. Gasses in the mobile phase in the detector can produce completely unacceptable noise and, thus, must be removed. The dissolved gasses were originally removed under vacuum but, unfortunately, are soon replaced if the solvent is left in contact with air at atmospheric pressure. For this reason degassing is now usually carried out by bubbling helium through the mobile phase reservoirs. Secondly, vacuum is used in the thermionic detector. This consists of a device, very similar in design to the thermionic valve which is attached to a vacuum and a small quantity of the eluent from a gas chromatography column allowed to bleed through it. Helium is used as the carrier gas. The presence of solute vapor causes the thermionic current to fall. This type of detector tends to become contaminated rather readily.
http://purl.obolibrary.org/obo/OBI_0000496	capillary column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A capillary column is a thin tube with a small inner diameter, usually around 0.5 mm.
http://purl.obolibrary.org/obo/OBI_0000497	sample inlet	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		The column inlet (or injector) provides the means to introduce a sample into a continuous flow of carrier gas. The inlet is a piece of hardware attached to the column head.
http://purl.obolibrary.org/obo/OBI_0000498	NMR tube washing system	http://purl.obolibrary.org/obo/OBI_0000968	device		An automatic cleaning system for NMR tubes that removes previous probe and sample residues in order to allow for tube recycling.
http://purl.obolibrary.org/obo/OBI_0000499	NMR console	http://purl.obolibrary.org/obo/OBI_0000968	device		A component of an NMR instrument that controls the activities of the other components.
http://purl.obolibrary.org/obo/OBI_0000500	dual loop autosampler	http://purl.obolibrary.org/obo/OBI_0000494	liquid chromatography autosampler		A dual loop autosampler is an autosampler that is designed for handling both analytical (10 mL/min flow rate) to preparative scale sample purification (100 mL/min flow rate).
http://purl.obolibrary.org/obo/OBI_0000501	variable wavelength detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A chromatography detector, that can detect signals within a certain range at user-defined wavelengths.
http://purl.obolibrary.org/obo/OBI_0000503	Bruker LC-NMR platform	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		The LC-NMR/MS setup was first introduced by Bruker BioSpin in 1999. An LC-NMR system including a Bruker Peak Sampling Unit (BPSU-36) was coupled with a Bruker Daltonics esquire series ion trap mass spectrometer via a Bruker NMR-MS interface (BNMI). Since October 2004 the Bruker Daltonics microTOF-LC time-of-flight mass spectrometer can also be integrated in an LC-NMR setup.
http://purl.obolibrary.org/obo/OBI_0000504	sample injection system	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		An automated chromatography system that injects the sample into the chromatography columns in order to increase speed and minimize human involvement in the purification process for  better reproducibility.
http://purl.obolibrary.org/obo/OBI_0000505	multiple wavelength detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A chromatography detector, that can detect many discrete wavelengths in parallel and produces a multiple wavelength chromatographic profile.
http://purl.obolibrary.org/obo/OBI_0000507	gas generator	http://purl.obolibrary.org/obo/OBI_0000542	gas chromatography equipment		An instrument that generates gases for use with the gas chromatograph. Previously gas was obtained from gas tanks or gas cylinders. However, over the past decade the use of gas generators have become more popular as it avoids having gases at high pressure in the laboratory which is perceived by some as potentially dangerous. In addition, the use of a hydrogen generator avoids the use of a cylinder of hydrogen at high pressure which is also perceived by some as a serious fire hazard despite the fact that they have been used in laboratories, quite safely for nearly a century.
http://purl.obolibrary.org/obo/OBI_0000508	column jacket	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A column jacket is a piece of column chromatography equipment that covers a column in order to ensure thermoisolation and create a controllable thermostatic microenvironment.
http://purl.obolibrary.org/obo/OBI_0000510	reversed phase column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A reversed phase column is a chromatography column in which the mobile phase is more polar than the stationary phase. Its counterpart is the normal phase column.
http://purl.obolibrary.org/obo/OBI_0000511	injector lubricant	http://purl.obolibrary.org/obo/OBI_0000601	chromatography consumable		A lubricant used in liquid chromatography that eases sample injector penetration.
http://purl.obolibrary.org/obo/OBI_0000512	isolation of cell population	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a process in which a population of cells with certain characteristics is isolated from a larger population
http://purl.obolibrary.org/obo/OBI_0000513	DISCOVERY console	http://purl.obolibrary.org/obo/OBI_0000599	tecmag NMR console		The Discovery console is a Windows XP Professional-based, integrated console designed especially for Solid-State NMR. The console includes everything needed to interface to any magnet and solids probe - from computer to cables to duplexing network.
http://purl.obolibrary.org/obo/OBI_0000514	Bruker AMX series NMR instrument	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		A series of older Bruker NMR magnets, now out of production. The Bruker AMX500 has proven an extremely reliable workhorse, with excellent lineshape yielding superior water suppression even without gradients. The Oxford 11.7 Tesla 5.2 cm bore magnet rests on a TMC vibration damping table. Homogeneity is controlled by a BSN-18 and BSN-2 with 19 shim controls. In addition to the 5 mm triple resonance probe, the AMX is equipped with a 10mm broadband observe probe.
http://purl.obolibrary.org/obo/OBI_0000515	chromatofocusing column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A chromatofocusing column is a chromatography column in which a resin is equilibrated at one pH and eluted at a second pH. The use of a weak ion-exchange resin causes a pH gradient to be formed at the solvent front owing to the buffering action of the resin. This pH gradient in turn leads to an ordering of proteins by isoelectric point. Molecules of charge sign opposite the resin bind; those of charge sign like the resin do not bind.
http://purl.obolibrary.org/obo/OBI_0000516	NMR probe	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		Part of an NMR instrument that detects the signals emitted from a sample. No single probe can perform the full range of experiments, and probes that are designed to perform more than one type of measurement usually suffer from performance compromises. The probe represents a rather fragile single point of failure that can render an NMR system completely unusable if the probe is dropped or otherwise damaged. Probes are usually characterised by Sample diameter and Frequency.n  alt The instrument that transmits and receives radiofrequency to and from the NMR sample.
http://purl.obolibrary.org/obo/OBI_0000517	NMR magnet	http://purl.obolibrary.org/obo/OBI_0000968	device		A magnet which induces a certain frequency (MHz) and which has a certain bore diameter.n  alt The NMR signal is a natural physical property of the certain atomic nuclei but it can only be detected with an external magnetic field. A magnet is a fundamental part of an NMR instrument which induces an electromagnetic force field (RF pulse) and by this excites and aligns the spins of the electrons of the NMR acquisition nucleus. It is usually a big (superconducting) electromagnet which is cooled by liquid helium and can be adjusted to a frequency between 200 and 950 MHz. The magnetic field strength is measured in Tesla or Gauss.
http://purl.obolibrary.org/obo/OBI_0000518	trap column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A trap column is a chromatography column which is used prior to a, e.g. mass spectrometry, separation to clean up or concentrate controlled amounts of samples prior to elution to a detector.
http://purl.obolibrary.org/obo/OBI_0000519	flow probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe that allows the automatized flow-through of a sample. The sample is aspirated via a syringe pump into the Flow probe, the NMR spectrum is acquired and when the experiment is complete, the sample is returned to back to an external source (well plate) or flushed to waste. Sometimes pulsed field gradients (PFG) can be established in flow probes.
http://purl.obolibrary.org/obo/OBI_0000522	vial	http://purl.obolibrary.org/obo/OBI_0000967	container		A container made from solid material and primarily used for holding liquid.
http://purl.obolibrary.org/obo/OBI_0000524	Varian VXR spectrometer	http://purl.obolibrary.org/obo/OBI_0000611	Varian NMR instrument		A Varian NMR spectrometer.
http://purl.obolibrary.org/obo/OBI_0000525	splitless GC injector	http://purl.obolibrary.org/obo/OBI_0000504	sample injection system		Injected sample enters column immediately (while split valve to split vent is closed). Here a sample is introduced into a heated small chamber via a syringe through a septum - the heat facilitates volatilization of the sample and sample matrix. The carrier gas then either sweeps the entirety (splitless mode) or a portion (split mode) of the sample into the column. In split mode, a part of the sample/carrier gas mixture in the injection chamber is exhausted through the split vent.
http://purl.obolibrary.org/obo/OBI_0000526	preparative autosampler	http://purl.obolibrary.org/obo/OBI_0000494	liquid chromatography autosampler		For preparative LC with injection of sample volumes ranging from L to mL ranges.
http://purl.obolibrary.org/obo/OBI_0000528	liquid chromatography valve	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A sample valve that must be able to sustain pressures up to 10,000 p.s.i., although it is most likely to operate on a continuous basis, at pressures of 3,000 p.s.i. or less. The higher the operating pressure the tighter the valve seating surfaces must be forced together to eliminate any leak. It follows that any abrasive material, however fine, that passes into the valve can cause the valve seating to become scored each time it is rotated which will ultimately lead to leaks. This will cause the sample size to vary between samples and eventually affect the accuracy of the analysis. It follows that any solid material must be carefully removed from any sample before filling the valve. The sample volume of an internal loop valve is situated in the connecting slot of the valve rotor and can be used only for relatively small sample volumes. Internal sample loop valves provide samples with volumes ranging from 0.1 ml to about 0.5 ml. Valve operation is shown in figure 6. The left-hand side diagram shows the load position. The sample occupies the rotor slot and has been filled by passing the sample from an appropriate syringe through the rotor slot to waste. While loading the sample, the mobile phase supply is passed through the valve directly to the column. To place the sample onto the column, the valve is then rotated and the valve slot containing the sample is now placed between the solvent supply and the column. As a result, the sample is passed into the column by the flow of solvent.
http://purl.obolibrary.org/obo/OBI_0000529	JEOL NMR probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe that is manufactured by JEOL.
http://purl.obolibrary.org/obo/OBI_0000530	Bruker UltraShield Plus NMR magnet	http://purl.obolibrary.org/obo/OBI_0000597	Bruker NMR magnet		An NMR magnet of which Brukers claims it is the latest and most advanced self-shielding NMR magnet technology ever developed. These magnets are the ultimate advancement in high performance, actively-shielded NMR solutions. They offer unprecedented shielding performance whilst ensuring no compromise in system homogeneity, stability or cryogenic specifications.
http://purl.obolibrary.org/obo/OBI_0000531	Bruker CryoProbe	http://purl.obolibrary.org/obo/OBI_0000561	Bruker NMR probe		The Bruker BioSpin CryoProbe is a high-performance cryogenically cooled probe developed for high-resolution applications. It has improved signal/noise (S/N) ratios obtained by reducing the operating temperature of the coil and the pre-amplifier. As a result, the efficiency of the coil is improved and the noise of the coil and the pre-amplifier are reduced.The dramatic increase in the S/N ratio by a factor of 3-4, as compared to conventional probes, leads to a possible reduction in experiment time of up to 16 or a reduction in required sample concentration by a factor of up to 4. The CryoProbes possess key characteristics for NMR analysis:n   Significant S/N gains (with moderately salty samples also)n   Short pulse widthsn   Short ring down timesn   Linear behavior in power responsen   Gradient capabilityn   CryoProbes are available as Triple Resonance, Dual, Selective X Detection, MicroImaging, and Quad Nucleus Probes configurations at 400 MHz and highern   All high resolution probes have a lock circuitn   All high resolution probes have Z-gradient.
http://purl.obolibrary.org/obo/OBI_0000532	column cartridge	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A device that binds the chromatography column and additional connector elements and / or valves or syringes into one physical unity for further processing.
http://purl.obolibrary.org/obo/OBI_0000533	affinity column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		An affinity column is a chromatography column that is used in affinity chromatography. Differences in the affinity of molecules to be separated to a stationary phase are used for discriminate retention.
http://purl.obolibrary.org/obo/OBI_0000534	tecmag NMR instrument	http://purl.obolibrary.org/obo/OBI_0000566	NMR instrument		An NMR instrument that is manufactured by tecmag.
http://purl.obolibrary.org/obo/OBI_0000535	gel filtration column	http://purl.obolibrary.org/obo/OBI_0000618	size exclusion column		A Gel filtration column is a chromatography column for size-exclusion chromatography, in which the stationary phase is a gel. The main application of gel filtration chromatography is the fractionation of proteins and other water-soluble polymers.
http://purl.obolibrary.org/obo/OBI_0000536	fraction collector	http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument		A fraction detector is a device that allows regular or specified samples to be taken from a column eluate and stored in a retrievable form. The storage vessels are usually small sample tubes or vials that are oriented in a rotating disk or in a moving belt, there movement usually being controlled by a microprocessor. On receiving a signal from the microprocessor, the next vial is placed under the column outlet and the eluate collected until receiving another signal from the computer. Once the properties of the chromatogram that describes the separation has been ascertained, then the collection program can be defined. The fractions can be collected on a basis of time either at regular intervals or a specific times to collect specific peaks. Alternatively the fractions can be collected by monitoring the detector output and when a peak starts to elute the fraction collector is activated and the peak collected in a specific vial. When the peak returns to base line the column eluate is then directed to waste until the next peak starts eluting. Fraction collectors are in common use with most liquid chromatographs. They are used to collect samples for further purification, subsequent examination by spectroscopic techniques or for biological or organoleptic testing.
http://purl.obolibrary.org/obo/OBI_0000538	in-line filter	http://purl.obolibrary.org/obo/OBI_0000592	chromatography detector filter		A solvent filter that sits between the pump and the injection valve that prevents dust particles, general debris and, to some extent, bacteria from entering the chromatography system. Contaminants can interfere with the low-pressure gradient former or the pump and particles entering valves may interfere with the proper function. The result could cause an increased baseline noise, non-repeatable gradient forming, unreliable flow rate or other interferences. Solvent in-line filters are low-pressure filters and will allow a high flow rate due to a large surface area and large porosity.
http://purl.obolibrary.org/obo/OBI_0000539	imaging NMR probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe that is designed for generating pictures from sample states via NMR imaging.
http://purl.obolibrary.org/obo/OBI_0000540	isolation of adherent cells	http://purl.obolibrary.org/obo/OBI_0000512	isolation of cell population		a material separation process in which cells that stick to the container in which they are grown as a cell culture are separated from those in the liquid component of the culture. The output of this process are adherent cells.
http://purl.obolibrary.org/obo/OBI_0000541	Bruker AC series NMR instrument	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		A series of older Bruker NMR magnets, now out of production.
http://purl.obolibrary.org/obo/OBI_0000542	gas chromatography equipment	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		Any device used in a gas chromatography experiment.
http://purl.obolibrary.org/obo/OBI_0000543	syringe filter	http://purl.obolibrary.org/obo/OBI_0000592	chromatography detector filter		A small membrane filter of defined pore size, that filters samples from a syringe.
http://purl.obolibrary.org/obo/OBI_0000544	Bruker SampleRail system	http://purl.obolibrary.org/obo/OBI_0000968	device		This Instrument system automatically prepares an NMR sample, inserts it into an NMR magnet, performs NMR experiments on the sample, and transports it back to the preparation system.   The SampleRail fulfills the transporting tasks from the preparation system into the NMR magnet and back.
http://purl.obolibrary.org/obo/OBI_0000545	column compartment	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		For chromatography analyses, the ability to maintain a stable column environment regardless of ambient temperature fluctuations is critical for maintaining retention time precision. In order to ensure such stable conditions at different chromatography steps a column compartment can be installed that ensures e.g. stable temperature of the column in a given step.
http://purl.obolibrary.org/obo/OBI_0000546	capillary pump system	http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system		A pump system optimized for capillary chromatography.
http://purl.obolibrary.org/obo/OBI_0000547	evaporative light scattering detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		The evaporative light scattering detector, as its name implies, utilizes a spray that continuously atomizes the column eluent into small droplets. These droplets are allowed to evaporate, leaving the solutes as fine particulate matter suspended in the atomizing gas.
http://purl.obolibrary.org/obo/OBI_0000548	isolation of PBMCs	http://purl.obolibrary.org/obo/OBI_0000512	isolation of cell population		a process in which cells with a single nucleus are isolated from a blood sample
http://purl.obolibrary.org/obo/OBI_0000549	column cartridger	http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument		A chromatography device where the column cartridge is inserted into and stabilised.
http://purl.obolibrary.org/obo/OBI_0000550	nitrogen generator	http://purl.obolibrary.org/obo/OBI_0000507	gas generator		A gas generator that generates nitrogen gas.
http://purl.obolibrary.org/obo/OBI_0000551	needle assembly	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		The needle assembly attached to the autosampler, comprises the injector needle that feeds a sample or carrier gas into the inlet
http://purl.obolibrary.org/obo/OBI_0000553	Bruker Capillary LC-NMR platform	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		Capillary LC-NMR is a hyphenated technique coupling capillary liquid chromatography and NMR, which increases sensitivity dramatically through the use of miniaturization of the chromatographic techniques and NMR detection volume. LC-NMR hyphenated systems separate a mixture into its pure components and couple the output to NMR for automatic sample analysis. The ever increasing need to measure lower sample amounts and lower level impurities demands the highest NMR sensitivity. Traditional LC-NMR systems with relatively large peak volumes are not optimized for such low levels of detection. Bruker BioSpin, together with Waters and Protasis has developed a Capillary LC-NMR system. The latest capillary LC attributes and highest capillary flow probe sensitivity combine with state of the art NMR systems technology. Greater mass sensitivity and faster spectral analysis with smaller sample volumes is possible. This system is ideal for analysis of metabolites and impurities associated with the drug development process.
http://purl.obolibrary.org/obo/OBI_0000554	gas chromatography oven	http://purl.obolibrary.org/obo/OBI_0000542	gas chromatography equipment		A gas chromatography oven is an oven with a heated connection between the GC and the MS instrument in a GCMS-analysis, that keeps compounds in the gas phase as they leave the GC oven.
http://purl.obolibrary.org/obo/OBI_0000555	autosampler	http://purl.obolibrary.org/obo/OBI_0000968	device		An optional part of an NMR instrument used to hold samples prior to NMR analysis and that sequentially loads these samples into the analytical part of the NMR instrument. n   alt The autosampler is an automatic sample changer device.
http://purl.obolibrary.org/obo/OBI_0000556	isocratic pump system	http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system		A pump system optimized for isocratic chromatography.
http://purl.obolibrary.org/obo/OBI_0000557	flash pump system	http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system		Any pump system used in flash column chromatography to push the solvent through the column. Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).
http://purl.obolibrary.org/obo/OBI_0000558	Varian UNITY INOVA spectrometer	http://purl.obolibrary.org/obo/OBI_0000611	Varian NMR instrument		The UNITY INOVA is also the easiest spectrometer to use and is also the choice of those interested in using advanced NMR techniques in their own research, but without becoming, or hiring, an NMR expert. A complete set of turnkey operating environments is available for the UNITY INOVA covering the structure and dynamics of biological macromolecules, small molecules, solids, and imaging. These packages put the combined NMR expertise of the entire Varian NMR community at your fingertips.
http://purl.obolibrary.org/obo/OBI_0000559	liquid NMR probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe that is designed to hold a liquid sample.
http://purl.obolibrary.org/obo/OBI_0000560	ion exchange column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		An ion exchange column is a chromatography column that is used in ion exchange chromatography and anion or cation exchange resins to enable separation.
http://purl.obolibrary.org/obo/OBI_0000561	Bruker NMR probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe that is manufactured by Bruker.
http://purl.obolibrary.org/obo/OBI_0000562	anion trap column	http://purl.obolibrary.org/obo/OBI_0000518	trap column		An anion trap column is a trap column and ion-exchange column which contains cationic anion-exchange resins.
http://purl.obolibrary.org/obo/OBI_0000563	fluorescene detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A single wavelength detector, where the excitation light wavelength is normally a mercury lamp generated high intensity UV light at 253.7 nm. Many substances that fluoresce will be excited by light of this wavelength and hence be detected.
http://purl.obolibrary.org/obo/OBI_0000564	tecmag EAGLE probe	http://purl.obolibrary.org/obo/OBI_0000479	solid NMR probe		The Eagle is a 4 mm 1H/X solid-state MAS probe with a top spinning speed of 18 kHz. Its simple design is robust, reliable and easy to spin. Configurations are available for 200 to 600 MHz wide bore magnets on Tecmag, Bruker, Chemagnetics, JEOL and Varian spectrometers.
http://purl.obolibrary.org/obo/OBI_0000565	electrical conductivity detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		The electrical conductivity detector measures the conductivity of the mobile phase. There is usually background conductivity which must be backed-off by suitable electronic adjustments. If the mobile phase contains buffers, the detector gives a base signal that completely overwhelms that from any solute usually making detection impossible. Thus, the electrical conductivity detector a bulk property detector. and senses all ions whether they are from a solute or from the mobile phase. In order to prevent polarization of the sensing electrodes, AC voltages must be used and so it is the impedance not the resistance of the electrode system that is actually measured. From a physical chemistry stand point the conductivity of a solution is more important than its resistance. However, it is the resistance (impedance) of the electrode system that determines the current across it. The resistance of any conductor varies directly as its length and inversely as its cross sectional area.
http://purl.obolibrary.org/obo/OBI_0000567	Bruker UltraShield NMR magnet	http://purl.obolibrary.org/obo/OBI_0000597	Bruker NMR magnet		An NMR magnet manufactured by Bruker that ensures field homogeneity without amplified effects from vibrations or thermal changes. This magnet technology uses active shielding and optimizes coil design.
http://purl.obolibrary.org/obo/OBI_0000568	piston-seal	http://purl.obolibrary.org/obo/OBI_0000601	chromatography consumable		The seal made by a piston in a diaphragm pump. The unique property of the reciprocating diaphragm pump is that the actuating piston does not come into direct contact with the mobile phase and thus, the demands on the piston-cylinder seal are not so great. The diaphragm has a relatively high surface area and thus, the movement of the diaphragm is relatively small and consequently the pump can be operated at a fairly high frequency. High frequency pumping results in a very significant reduction in pulse amplitude and, in addition, high frequency pulses are more readily damped by the column system. Nevertheless, it must be emphasized that diaphragm pumps are not pulseless.
http://purl.obolibrary.org/obo/OBI_0000570	spin column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A spin column is a chromatography column which is suitable for putting it into a centrifuge. A spin column enforces separation through increased G-forces while spinning the column in a centrifuge. It is often used in DNA gel extraction kits.
http://purl.obolibrary.org/obo/OBI_0000571	manufacturer role	http://purl.obolibrary.org/obo/BFO_0000023	role		Manufacturer role is a role which inheres in a person or organization and which is realized by a manufacturing process.
http://purl.obolibrary.org/obo/OBI_0000572	transfer line	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A combination of devices that are used in connection with a sampling head for transferring components of an applied sample to the analyzing part of a chromatography system.
http://purl.obolibrary.org/obo/OBI_0000573	gradient pump system	http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system		A pump system optimized for gradient chromatography.
http://purl.obolibrary.org/obo/OBI_0000574	high temperature column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A high temperature column is a chromatography column which is suitable for and withstands very high temperatures in chromatography ovens.
http://purl.obolibrary.org/obo/OBI_0000575	Bruker Ultrastabilized NMR magnet	http://purl.obolibrary.org/obo/OBI_0000597	Bruker NMR magnet		An NMR magnet manufactured by Bruker for Ultra-High Field NMR, available from 750 MHz to 900 MHz, which provides reliable operation at reduced temperature and ambient pressure via being rigidly mounted and stabilized.
http://purl.obolibrary.org/obo/OBI_0000577	obsolete_molecular concentration	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A concentration is a relational quality that inheres in a material entity towards molecular scattered aggregate that is part of it by virtue of some ratio of masses of the two or the counts of the grains of the two or volume occupied by the larger material entity.
http://purl.obolibrary.org/obo/OBI_0000578	NMR sample tube	http://purl.obolibrary.org/obo/OBI_0000836	test tube		The sample-tube holds the NMR sample and sits in the nmr probe. It is usually a glass tube of 5-20mm diameter.
http://purl.obolibrary.org/obo/OBI_0000579	Varian UNITY spectrometer	http://purl.obolibrary.org/obo/OBI_0000611	Varian NMR instrument		The predecessor series of the Varian UNITY INOVA spectrometer.
http://purl.obolibrary.org/obo/OBI_0000580	AVANCE II spectrometer	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		A spectrometer suitable for metabolomics and in vivo NMR studies but structural analysis of small molecules and low molecular weight proteins can also be performed. To accomplish these studies there are six probe-heads available. A successor, the AVANCE III came out recently.
http://purl.obolibrary.org/obo/OBI_0000581	y-column connector	http://purl.obolibrary.org/obo/OBI_0000478	column connector		A column connector that connects one column on one side with two columns at the other side, hence building a Y shaped structure.
http://purl.obolibrary.org/obo/OBI_0000582	Bruker LC-NMR/MS platform	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		Includes the connection to a high-resolution TOF-LC-MS system.
http://purl.obolibrary.org/obo/OBI_0000583	refractive index detector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		For analyzing non-UV absorbing substances, such as carbohydrates, lipids and polymers. This is also the detector of choice for gel permeation chromatography. The refractive index detector is one of the least sensitive LC detectors. It is very sensitive to changes in ambient temperature, pressure changes, flow-rate changes and can not be used for gradient elution. Despite these many disadvantages, this detector is extremely useful for detecting those compounds that are nonionic, do not adsorb in the UV, and do not fluoresce. There are many optical systems used in refractive index detectors but one of the most common is the differential refractive index detector.
http://purl.obolibrary.org/obo/OBI_0000584	anion exchange column	http://purl.obolibrary.org/obo/OBI_0000560	ion exchange column		An anion exchange column is a chromatography column that is used in anion exchange chromatography and which enables the separation of anion mixtures.
http://purl.obolibrary.org/obo/OBI_0000586	plunger column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A plunger column is a chromatography column with adjustable heigth control. By means of an adjustable endpiece (plunger) the user can adjust the column length without disturbing the packed bed. Plunger columns can equalize volume changes and thus avoids dead volumes within the column.
http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system	http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument		Better flow rates can be achieved by using a pump or by using compressed gas (e.g. air, nitrogen, or argon) to push the solvent through the column (flash column chromatography).
http://purl.obolibrary.org/obo/OBI_0000590	Bruker 1mm MicroProbe	http://purl.obolibrary.org/obo/OBI_0000561	Bruker NMR probe		Over the past few years there has been a significantly growing demand for miniaturization in all areas ofmodern research and development. Evoked by many exciting applications, there is a need for analytical methods which require less amounts of sample. Bruker BioSpin meets this challenge with a revolutionary NMR probe design: The 1mm MicroProbe. It operates with disposable 1mm capillary sample tubes and the sample volume of 5 microliters enables the use of lowest amounts of sample to run all high resolution NMR experiments with outstanding sensitivity and up to 16 times faster measurements. Due to the TXI-type probe design, the z-gradient coil and the automatic matching and tuning accessory, the 1mm MicroProbe can be used for a wide variety of NMR experiments. The key advantages of this probe include:n   up to 4 times higher mass sensitivity than 5mm conventional probes (with respect to the same sample amount)n   excellent solvent suppression propertiesn   virtually no salt effectn   discrete samples in tubes that can be sealed and storedn   automation accessory for sample preparation and handling available.
http://purl.obolibrary.org/obo/OBI_0000592	chromatography detector filter	http://purl.obolibrary.org/obo/OBI_0000601	chromatography consumable		An optical filter that is used to obtain monochromatic light of a defined wavelength from detector lamps.
http://purl.obolibrary.org/obo/OBI_0000593	cation trap column	http://purl.obolibrary.org/obo/OBI_0000518	trap column		A cation trap column is a trap column and ion-exchange column which contains anionic cation-exchange resins.
http://purl.obolibrary.org/obo/OBI_0000594	column adapter	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		An Adapter that enabled the connection of a column to additional devices.
http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument	http://purl.obolibrary.org/obo/OBI_0000566	NMR instrument		An NMR instrument that is manufactured by Bruker.
http://purl.obolibrary.org/obo/OBI_0000597	Bruker NMR magnet	http://purl.obolibrary.org/obo/OBI_0000517	NMR magnet		An NMR magnet that is manufactured by Bruker.
http://purl.obolibrary.org/obo/OBI_0000598	ozone-induced chemiluminescence detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector		Although there are many direct ozone chemiluminescent reactions with various gaseous molecules, the incorporation of a conversion step to convert various non-chemiluminescent analytes to a species capable of reacting with ozone to produce chemiluminescence broadens the horizon of this technique tremendously. The conversion of nearly all nitrogen- and sulfur-containing compounds to their respective chemiluminescent species for universal nitrogen and sulfur detection has made nitrogen/sulfur chemiluminescence detection the most widely used analytical methods based upon ozone-induced chemiluminescence. In addition to non-chromatographic applications, nitrogen/sulfur chemiluminescence detection has been adapted to various chromatographic techniques from gas chromatography to liquid and supercritical fluid chromatography as specialized element-specific detectors. The characteristics of these detectors are evaluated and compared to other element-selective detection techniques. The unique features of the chemiluminescence detectors have made them powerful tools in many diverse fields of analytical chemistry.
http://purl.obolibrary.org/obo/OBI_0000599	tecmag NMR console	http://purl.obolibrary.org/obo/OBI_0000499	NMR console		An NMR console manufactured by tecmac.
http://purl.obolibrary.org/obo/OBI_0000600	JEOL NMR instrument	http://purl.obolibrary.org/obo/OBI_0000566	NMR instrument		An NMR instrument that is manufactured by JEOL.
http://purl.obolibrary.org/obo/OBI_0000601	chromatography consumable	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A chromatography consumable is a consumable that is used in a chromatography experiment.
http://purl.obolibrary.org/obo/OBI_0000602	column frit	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A part of the column content that separates column packing compartments. In radial columns the packing is supported between two cylindrical frits and the gap between represents the bed height or column length. The outer frit is the column inlet and consequently the sample initially has a large area of stationary phase with which to interact. Frits are porous metal products to prevent unwanted particles from entering the chromatography system. These particles may come from the sample, the solvent or debris generated by the chromatography system itself. Such particles entering the system may lead to clogging of capillaries, interference with the chromatography by changing chromatographic parameters or disturbance of the detector function. Characteristics of a frit, besides the diameter and the thickness, is the porosity (pore distribution, density).
http://purl.obolibrary.org/obo/OBI_0000603	liquid chromatography column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A liquid chromatography column is a chromatography column that is used in liquid chromatography, i.e. a column that is provided with a liquid sample mix.
http://purl.obolibrary.org/obo/OBI_0000604	detector lamp	http://purl.obolibrary.org/obo/OBI_0000601	chromatography consumable		A lamp used in a chromatography detector that excites sample molecules at certain frequencies / emission wavelengths, e.g. Mercury Vapor Lamp (253.7 nm), Zinc Vapor Lamp (2123.9 nm and 307.6 nm), Cadmium Vapor Lamp (228.8, 326.1,340.3, and 346.6 nm). To obtain monochromatic light an appropriate light filter would be needed.
http://purl.obolibrary.org/obo/OBI_0000605	chart recorder	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		The chart recorder is a device that transduces signal-intensities into a graphical peak output: As the separated components of the gas sample emerge into the detector, the change in voltage in the detecting bridge circuit causes a representative peak to be drawn on a chart recorder. The position of the peak along the time axis of the chart measures the component's retention time, which identifies the component. This is directly related to carrier gas flow rate, temperature and column packing and dimensions. The area under each peak is proportional to the concentration of the component of the sample. The area of the peaks inscribed on the chart recorder can be determined by multiplying the height of the peak in mm, by the width of the peak in mm at 1/2 the peak height. The calibration curves for use with the chart recorder are therefore peak area plotted against concentration.
http://purl.obolibrary.org/obo/OBI_0000606	open tubular column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		An open tubular column is a chromatography column in which the particles of the solid stationary phase or the support coated with a liquid stationary phase are concentrated on or along the inside tube wall leaving an open, unrestricted path for the mobile phase in the middle part of the tube.
http://purl.obolibrary.org/obo/OBI_0000608	hydrogen generator	http://purl.obolibrary.org/obo/OBI_0000507	gas generator		A gas generator that generates hydrogen gas.
http://purl.obolibrary.org/obo/OBI_0000609	glass column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A glass column is a chromatography column made out of glass that is usually used for larger scale and preparative liquid chromatography separations.
http://purl.obolibrary.org/obo/OBI_0000610	auto injector	http://purl.obolibrary.org/obo/OBI_0000504	sample injection system		A gas chromatography device that can auto-inject a small number of samples an inlet.
http://purl.obolibrary.org/obo/OBI_0000611	Varian NMR instrument	http://purl.obolibrary.org/obo/OBI_0000566	NMR instrument		An NMR instrument that is manufactured by Varian.
http://purl.obolibrary.org/obo/OBI_0000613	Bruker SPE-NMR platform	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		A Solid Phase Extraction (SPE) system provides an interface between liquid chromatography (LC) and NMR. For the process of LC-SPE  NMR a chromatographic separation is done and the peaks of interest are trapped on an individual SPE cartridge after the column. The peak selection is done either by UV detection or by evaluation of the on-line registered MS or MSn spectra.
http://purl.obolibrary.org/obo/OBI_0000614	guard column	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		Guard columns are installed between the injection valve and the analytical or preparative column and here will remove contaminants and prolong the lifetime of the columns.
http://purl.obolibrary.org/obo/OBI_0000617	fluorine-induced chemiluminescence detector	http://purl.obolibrary.org/obo/OBI_0000637	gas chromatography detector		A gas chromatographic detection system based on the low pressure, gas phase chemiluminescence of the reaction mixture of molecular fluorine with organo-sulfur, -selenium, and -tellurium compounds separated from (gas phase) headspace samples. This detector was originally developed in the research group of John Birks at the University of Colorado, USA and was manufactured and sold by Sievers Instruments (Boulder Colorado, USA). This system can be divided up into three parts: the chromatograph, transfer line, and reaction cell; PMT and photon counting electronics; and the molecular fluorine generator.
http://purl.obolibrary.org/obo/OBI_0000618	size exclusion column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A size exclusion column is a chromatography column as used in size exclusion chromatography and which enables the separation of mixtures according to differrences in molecular size.
http://purl.obolibrary.org/obo/OBI_0000619	chromatography splitter	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		An adjustable restriction that is placed in the waste outlet to allow the necessary pressure to develop at the column inlet to force a flow (q ml/min) through the column. If the flow of mobile phase is Q ml/min then the waste flow will be (Q-q) ml/min. by adjusting the waste flow, the proportion of the sample entering the capillary column can be varied over a wide range of values and the necessary minimum permissible volume for the particular column in use can be selected for analysis. Unfortunately, the fraction taken in this way may not be representative of the original sample. This is due to the individual solutes in the mixture having different diffusivities and, thus, they distribute themselves across the sampling tube in an irregular manner. In general, the components with higher diffusivities (e.g., those solutes of lower molecular weight) will diffuse away from the bulk sample more quickly than those having lower diffusivities.
http://purl.obolibrary.org/obo/OBI_0000620	Bruker micro imaging probe	http://purl.obolibrary.org/obo/OBI_0000561	Bruker NMR probe		For medical, biological and material sciences research, avance imaging systems provide optimal object handling and performance with a variety of samples types. Two classes of imaging probes are available: in vivo probes for handling and sustaining live objects such as animals and plants, and conventional imaging probes for materials samples.
http://purl.obolibrary.org/obo/OBI_0000621	custom made column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A custom made column ia a chromatography column which is specifically tailored according to the needs of the separation as requested by a scientist or working group.
http://purl.obolibrary.org/obo/OBI_0000622	gel permeation column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		A gel permeation column is a chromatography column which is used in gel permeation chromatography and which employs as the stationary phase a swollen gel made by polymerizing and cross-linking styrene in the presence of a diluent which is a nonsolvent for the styrene polymer. The polymer to be analyzed is introduced at the top of the column and then is elutriated with a solvent. The polymer molecules diffuse through the gel at rates depending on their molecular size.
http://purl.obolibrary.org/obo/OBI_0000624	Bruker SampleJet system	http://purl.obolibrary.org/obo/OBI_0000464	Bruker autosampler		Bruker BioSpin introduces the SampleJet, a robot for NMR tube automation. The SampleJet has been consciously designed to meet the growing customer demand for simplicity, versatility and higher throughput in NMR sample tube automation.n  The SampleJet utilizes the modern-day industry standard for sample arrangements-the 96 well plate array. Therefore, the samples may be handled by standard lab automation devices before or after the NMR measurement.
http://purl.obolibrary.org/obo/OBI_0000625	JEOL ECX NMR spectrometer	http://purl.obolibrary.org/obo/OBI_0000600	JEOL NMR instrument		The ECX series of NMR spectrometers is designed for any laboratory needing an easy-to-use, reliable, routine NMR system. The ECX NMR series is available from 300 to 500 MHz. The console is designed around a modular, digital NMR electronics chassis controlled by an intelligent acquisition computer. For unprecedented flexibility, the JEOL NMR system offers a Windows XP, Mac OSX or LINUX. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.
http://purl.obolibrary.org/obo/OBI_0000627	quaternary pump system	http://purl.obolibrary.org/obo/OBI_0000589	chromatography pump system		A pump system that pump and mix up to four different solvents in parallel.
http://purl.obolibrary.org/obo/OBI_0000628	carbon nanotube column	http://purl.obolibrary.org/obo/OBI_0000038	chromatography column		Carbon nanotubes (CNTs) are known to have high thermal and mechanical stability and have the potential to be high-performance separation media that utilize the nanoscale interactions. CNT can be applied in long capillary tubes for the development of gas chromatography columns. A film of CNTs can be deposited by chemical vapor deposition (CVD) to form the stationary phase in the open tubular format. Altering the CVD conditions can vary the thickness and the morphology of the CNT film, which opens the possibility of selectivity tuning. The ability to fabricate long tubes coated with CNTs can be readily employed in other gas- and liquid-phase separations as well.
http://purl.obolibrary.org/obo/OBI_0000631	Varian MERCURY spectrometer	http://purl.obolibrary.org/obo/OBI_0000611	Varian NMR instrument		MERCURYplus spectrometers provide superior control, stability, and performance for high-productivity environments. Surface-mount electronics enable a small footprint without compromising data quality. Modular design allows flexible configuration. Direct digital synthesis, linear amplifiers, and other innovative RF and digital technologies enable push-button operation.
http://purl.obolibrary.org/obo/OBI_0000632	Bruker Metabolic Profiler	http://purl.obolibrary.org/obo/OBI_0000596	Bruker NMR instrument		An NMR platform for conducting metabonomics studies, traditional metabolism studies, and analysis of complex mixtures, featuring an Avance NMR spectrometer and a microTOF from Bruker Daltonics. By combining the structural resolving power of NMR with mass accuracy of the microTOF Bruker offers a complete system for metabolic research. The Metabolic Profiler provides a simple, easy to use and inexpensive base-system to acquire the spectroscopic data, needed to do basic metabolic profiling including metabonomic statistical analysis.
http://purl.obolibrary.org/obo/OBI_0000633	column heater	http://purl.obolibrary.org/obo/OBI_0000485	chromatography instrument		The glass liner can be fitted with a separate heater and the volatilization temperature can, thus, be controlled. This flash heater system is available in most chromatographs. By using a syringe with a long needle, the tip can be made to penetrate past the liner and discharge its contents directly into the column packing. This procedure is called 'on-column injection' and, as it reduces peak dispersion on injection and thus, provides higher column efficiencies, is often the preferred procedure.
http://purl.obolibrary.org/obo/OBI_0000635	JEOL CapNMR probe	http://purl.obolibrary.org/obo/OBI_0000529	JEOL NMR probe		The JEOL ECA and ECX NMR spectrometers now support the MRM/Protasis CapNMR Probe for well plate-based and microvial-based NMR analysis. The CapNMR probe is available at proton frequencies ranging from 300 MHz to 800 MHz in both indirect configurations (e.g. 1H{13C} and 1H {31P}) and also in triple resonance configurations (e.g. 1H{13C, 15N}, 1H{31P, 15N}). Both employ a high-strength z-directed field gradient. The flowprobes come with the choice of two flowcell volumes: a 5 μl flowcell with an NMR active volume of 2.5 μl, and a 10 μl flowcell with an NMR active volume of 5 μl. The fluidic connections are 75 μm i.d. and 1/32 o.d. FEP Teflon with hastelloy unions for exceptional solvent compatibility.
http://purl.obolibrary.org/obo/OBI_0000636	acquisition computer	http://purl.obolibrary.org/obo/OBI_0400107	computer		A Computer used for NMR, can be divided into central processing unit (CPU), consisting of instruction, interpretation and arithmetic unit plus fast access memory, and peripheral devices such as bulk data storage and input and output devices (including, via the interface, the spectrometer). Under software control, the computer controls the RF pulses and gradients necessary to acquire data, and process the data to produce spectra or images. Note that devices such as the spectrometer may themselves incorporate small computers.
http://purl.obolibrary.org/obo/OBI_0000638	gas purifier	http://purl.obolibrary.org/obo/OBI_0000542	gas chromatography equipment		Gas purifiers are instruments used for the removal of gas impurities like hydrocarbons, oxygen, and moisture from carrier gas and fuel gases for GC or GC-MS systems.
http://purl.obolibrary.org/obo/OBI_0000639	material separation objective	http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective		is an objective to transform a material entity into spatially separated components.
http://purl.obolibrary.org/obo/OBI_0000640	indirect detection probe	http://purl.obolibrary.org/obo/OBI_0000516	NMR probe		An NMR probe designed to allow the indirect detection of acquisition nuclei.
http://purl.obolibrary.org/obo/OBI_0000641	JEOL ECA NMR spectrometer	http://purl.obolibrary.org/obo/OBI_0000600	JEOL NMR instrument		The ECA series of NMR spectrometers is a high performance, research grade NMR system configurable to a wide range off applications. The ECA NMR is available from 300 to 930 MHz field strengths and is 1GHz ready. The system is designed around a modular, digital NMR electronics chassis controlled from a UNIX or Windows workstation and acquisition system. Both the workstation and spectrometer may be connected to a standard network, allowing seamless remote operation anywhere in the world.
http://purl.obolibrary.org/obo/OBI_0000649	data set of features	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set that is produced as the output of a descriptive statistical calculation data transformation and consists of producing a data set that represents one or more features of interest about the input data set.
http://purl.obolibrary.org/obo/OBI_0000650	differential expression analysis data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A differential expression analysis data transformation is a data transformation that has an objective of differential expression analysis.  Frequently this data transformation involves summarizing or otherwise aggregating signals from various samples categorized into groups, and calculating measures of group differences from these aggregated signals.
http://purl.obolibrary.org/obo/OBI_0000651	urine specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		a portion of urine collected from an organism
http://purl.obolibrary.org/obo/OBI_0000652	material combination	http://purl.obolibrary.org/obo/OBI_0000094	material processing		is a material processing with the objective to combine two or more material entities as input into a single material entity as output.
http://purl.obolibrary.org/obo/OBI_0000653	fuzzy clustering objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A fuzzy clustering objective is a data transformation objective where the aim is to assign input objects (typically vectors of attributes) a probability that a point belongs to a class, where the number of class and their specifications are not known a priori.
http://purl.obolibrary.org/obo/OBI_0000654	device setting	http://purl.obolibrary.org/obo/BFO_0000019	quality		a quality inheres_in some device and is concretization of some (device_setting_specification and is_about a quality of the device
http://purl.obolibrary.org/obo/OBI_0000655	blood specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		a material entity derived from a portion of blood collected from an organism
http://purl.obolibrary.org/obo/OBI_0000656	data set of predicted values according to fitted curve	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set which is the output of a curve fitting data transformation in which the aim is to find a curve which matches a series of data points and possibly other constraints.
http://purl.obolibrary.org/obo/OBI_0000660	background corrected data set	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set that is produced as the output of a background correction data transformation.
http://purl.obolibrary.org/obo/OBI_0000662	error corrected data set	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set that is produced as the output of an error correction data transformation and consists of producing a data set which has had erroneous contributions from the input to the data transformation removed (corrected for).
http://purl.obolibrary.org/obo/OBI_0000664	BrdU incorporation assay	http://purl.obolibrary.org/obo/OBI_0000891	cell proliferation assay		A cell proliferation assay in which cells are cultured in the presence of BrdU which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle), substituting for thymidine during DNA replication, which can be quantified by BrdU specific antibodies.
http://purl.obolibrary.org/obo/OBI_0000666	background correction data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A background correction data transformation (sometimes called supervised classification) is a data transformation that has the objective background correction.
http://purl.obolibrary.org/obo/OBI_0000668	error correction data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		An error correction data transformation is a data transformation that has the objective of error correction, where the aim is to remove (correct for) erroneous contributions from the input to the data transformation.
http://purl.obolibrary.org/obo/OBI_0000669	tritiated thymidine incorporation assay	http://purl.obolibrary.org/obo/OBI_0000891	cell proliferation assay		A cell proliferation assay in which cells are cultured in the presence of tritiated thymidine which is incorporated into newly synthesized DNA of replicating cells (during the S phase of the cell cycle). The radioactivity of tritiated thymidine in a cell is a proxy for cells that were actively replicating.
http://purl.obolibrary.org/obo/OBI_0000671	sample from organism	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		a material obtained from an organism in order to be a representative of the whole
http://purl.obolibrary.org/obo/OBI_0000673	statistical hypothesis test	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A statistical hypothesis test data transformation is a data transformation that has objective statistical hypothesis test.
http://purl.obolibrary.org/obo/OBI_0000676	reduced dimension data set	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set that is produced as the output of a data vector reduction data transformation and consists of producing a data set which has fewer vectors than the input data set.
http://purl.obolibrary.org/obo/OBI_0000678	portioning objective	http://purl.obolibrary.org/obo/OBI_0000639	material separation objective		A material separation objective aiming to separate material into multiple portions, each of which contains a similar composition of the input material.
http://purl.obolibrary.org/obo/OBI_0000680	whole organism preparation	http://purl.obolibrary.org/obo/OBI_0100051	specimen		A material entity which is the output of a process in which one or more whole organisms are prepared in a way to make it easier to study them, and in which the great majority of organismal parts are maintained
http://purl.obolibrary.org/obo/OBI_0000681	separation into different composition objective	http://purl.obolibrary.org/obo/OBI_0000639	material separation objective		A material separation objective aiming to separate a material entity that has parts of different types, and end with at least one output that is a material with parts of fewer types (modulo impurities).
http://purl.obolibrary.org/obo/OBI_0000682	obsolete_study result	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		Study result is an information content entity  that is a specified data output of a study.
http://purl.obolibrary.org/obo/OBI_0000684	specimen collection objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed.
http://purl.obolibrary.org/obo/OBI_0000685	creating a mixture of molecules in solution	http://purl.obolibrary.org/obo/OBI_0000652	material combination		is a process with the objective to prepare a liquid solution of one or more chemicals at desired concentrations.
http://purl.obolibrary.org/obo/OBI_0000686	material combination objective	http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective		is an objective to obtain an output material that contains several input materials.
http://purl.obolibrary.org/obo/OBI_0000687	nucleotide overhang cloning	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		Nucleotide overhang cloning is the process of inserting nucleic acid into a vector using nucleotide overhangs used to prevent self ligation
http://purl.obolibrary.org/obo/OBI_0000688	rodent care protocol	http://purl.obolibrary.org/obo/OBI_0000715	animal care protocol		A rodent care protocol is an animal protocol in which the animals being taken care of are rodents.
http://purl.obolibrary.org/obo/OBI_0000690	immunoprecipitation	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		is a process which realizes a material separation objective by relying on antibodies to specifically binding to material entity
http://purl.obolibrary.org/obo/OBI_0000691	ABI 377 automated sequencer	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer		is a DNA sequencer which is manufactured by Applied Biosystems corporation (formerly Perkin-Elmer). It allows automated chain termination DNA sequencing. It has part polyacrylamide gel electrophoresis system and a laser -based detection system to detect fluorescence intensity emitted by the dyes attached to the dideoxyterminator nucleotides or to the primers.
http://purl.obolibrary.org/obo/OBI_0000692	recombination enzyme based cloning	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		a recombination enzyme based cloning is a recombinant vector cloning process that uses complementary nucleotide sequences in both the insert genetic material and the cloning vector with a recombination enzyme to directly create a recombinant vector
http://purl.obolibrary.org/obo/OBI_0000694	animal feeding	http://purl.obolibrary.org/obo/OBI_0000011	planned process		animal feeding is a process in which animals are provided with food
http://purl.obolibrary.org/obo/OBI_0000696	AB SOLiD System	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer		is a DNA sequencer which is manufactured by Applied Biosystems and which enable DNA sequencing by ligation
http://purl.obolibrary.org/obo/OBI_0000699	survival assessment assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the occurrence of death events in one or more organisms over time
http://purl.obolibrary.org/obo/OBI_0000703	Illumina Genome Analyzer II	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer		is a DNA sequence which is manufactured by Illumina (Solexa) corporation. it support sequencing of single or paired end clone libraries relying on sequencing by synthesis technology
http://purl.obolibrary.org/obo/OBI_0000704	decision tree induction objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A decision tree induction objective is a data transformation objective in which a tree-like graph of edges and nodes is created and from which the selection of each branch requires that some type of logical decision is made.
http://purl.obolibrary.org/obo/OBI_0000705	Edman degradation	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay		A sequencing assay in which the amino acid sequence of input peptides or proteins is determined by iteratively cleaving of the amino-terminal (N-terminal) residue without disrupting the peptide bonds and identifying it by e.g. chromatography or electropheresis.
http://purl.obolibrary.org/obo/OBI_0000706	SOLiD sequencing assay	http://purl.obolibrary.org/obo/OBI_0000723	DNA sequencing by ligation assay		A DNA sequencing by ligation assay that identifies sequence information using primers to hybridize to the P1 adapter sequence within the library template, fluorescently labeled di-base probes to compete for ligation to the sequencing primer, multiple cycles of ligation, detection and cleavage to determine the eventual read length, following a series of ligation cycles, the extension product is removed and the template is reset with a primer complementary to the n-1 position for a second round of ligation cycles.
http://purl.obolibrary.org/obo/OBI_0000707	decision tree building data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A decision tree building data transformation is a data transformation that has objective decision tree induction.
http://purl.obolibrary.org/obo/OBI_0000708	laboratory animal care	http://purl.obolibrary.org/obo/OBI_0000011	planned process		a process that realizes an animal care protocol that specifies how animals are kept and maintained
http://purl.obolibrary.org/obo/OBI_0000710	Li-Cor 4300 DNA Analysis System	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer		is a DNA sequencer which is manufactured by Li-Cor corporation and enable automated chain termination based DNA sequencing
http://purl.obolibrary.org/obo/OBI_0000712	pathogen challenge	http://purl.obolibrary.org/obo/OBI_0003456	in vivo challenge		The administration of a live pathogenic organism to a host.
http://purl.obolibrary.org/obo/OBI_0000713	GenePattern software	http://purl.obolibrary.org/obo/IAO_0000010	software		a software that provides access to more than 100 tools for gene expression analysis, proteomics, SNP analysis and common data processing tasks.
http://purl.obolibrary.org/obo/OBI_0000714	graph of vertices	http://purl.obolibrary.org/obo/IAO_0000038	graph		A construct that consists of many nodes connected with edges. The edges represent a relationship between the objects represented by the nodes.  A graph can be equivalently represented as a matrix.
http://purl.obolibrary.org/obo/OBI_0000715	animal care protocol	http://purl.obolibrary.org/obo/OBI_0000272	protocol		An animal care protocol is a protocol which specifies the environment in which animals are being kept in captivity for research purposes
http://purl.obolibrary.org/obo/OBI_0000717	HeliScope Single Molecule Sequencer	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer		is a DNA sequencer manufacturer by Helicos Corporation to carry out Single Molecule sequencing using reversible termination chemistry
http://purl.obolibrary.org/obo/OBI_0000718	pathogen role	http://purl.obolibrary.org/obo/BFO_0000023	role		pathogen role is a role which inheres in an organism and realized in the process of disease course in the organism bearing host role caused by the organism bearing pathogen role
http://purl.obolibrary.org/obo/OBI_0000719	vaccine production	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A planned process with the objective to create a vaccine.
http://purl.obolibrary.org/obo/OBI_0000720	immunologic adjuvant role	http://purl.obolibrary.org/obo/OBI_1110092	adjuvant role		The role a material entity plays when it is co-administered with an immunogen in order to enhance the immune response to the immunogen.
http://purl.obolibrary.org/obo/OBI_0000721	glucose tolerance test	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures glucose clearance from blood over time by repeated glucose measurement in blood serum or plasma after the administration of a glucose bolus in-vivo. This assay can be used to evaluate the severity of insulin resistance or the efficiency of glucose clearance.
http://purl.obolibrary.org/obo/OBI_0000723	DNA sequencing by ligation assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay		A DNA sequencing assay that performs chain extension during the sequencing reaction step using DNA ligase
http://purl.obolibrary.org/obo/OBI_0000725	host role	http://purl.obolibrary.org/obo/BFO_0000023	role		host role is a role played by an organism and realized by providing nourishment, shelter or a means of reproduction to another organism within the organism playing the host role
http://purl.obolibrary.org/obo/OBI_0000726	peak matching	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Peak matching is a data transformation performed on a dataset of a graph of ordered data points (e.g. a spectrum) with the objective of pattern matching local maxima above a noise threshold
http://purl.obolibrary.org/obo/OBI_0000728	rodent care	http://purl.obolibrary.org/obo/OBI_0000708	laboratory animal care		rodent care  is the process by which rodents are being provided with a controlled living environment while kept in captivity for the purpose of research.
http://purl.obolibrary.org/obo/OBI_0000729	cloning plasmid	http://purl.obolibrary.org/obo/OBI_0000737	cloning vector		A cloning plasmid is a plasmid that was engineered to contain a bacterial origin of replication, encodes for a selectable gene product and contains a cloning site.
http://purl.obolibrary.org/obo/OBI_0000730	pyrosequencing assay	http://purl.obolibrary.org/obo/OBI_0000734	DNA sequencing by synthesis assay		A DNA sequencing by synthesis assay which sequences a single strand of DNA by synthesizing the complementary strand along it, one base pair at a time, and detecting which base was actually added at each step. The template DNA is immobilized, and solutions of A, C, G, and T nucleotides are added and removed after the reaction, sequentially. Light is produced only when the nucleotide solution complements the first unpaired base of the template. The sequence of solutions which produce chemiluminescent signals allows the determination of the sequence of the template. ssDNA template is hybridized to a sequencing primer and incubated with the enzymes DNA polymerase, ATP sulfurylase, luciferase and apyrase, and with the substrates adenosine 5-prime phosphosulfate (APS) and luciferin.
http://purl.obolibrary.org/obo/OBI_0000731	recombinant vector	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A recombinant vector is created by a recombinant vector cloning process, and contains nucleic acids that can be amplified. It retains functions of the original cloning vector.
http://purl.obolibrary.org/obo/OBI_0000732	restriction enzyme	http://purl.obolibrary.org/obo/PR_000000001	protein		an enzyme that has a specific target cleavage sites within nucleic acids
http://purl.obolibrary.org/obo/OBI_0000734	DNA sequencing by synthesis assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay		A DNA sequencing assay that relies on DNA polymerase activity to perform chain extension during the sequencing reaction step.
http://purl.obolibrary.org/obo/OBI_0000735	NTP-2000	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a material consisting of 14.5% protein, 8.5% fat and 9.5% fiber produced to feed rodents
http://purl.obolibrary.org/obo/OBI_0000737	cloning vector	http://purl.obolibrary.org/obo/CHEBI_33696	nucleic acid		A cloning vector is an engineered material that is used as an input material for a recombinant vector cloning process to carry inserted nucleic acids. It contains an origin of replication for a specific destination host organism, encodes for a selectable gene product and contains a cloning site.
http://purl.obolibrary.org/obo/OBI_0000738	restriction enzyme based cloning	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		restriction enzyme based cloning is a recombinant vector cloning process that has as an input genetic material that was cleaved with restriction enzymes, and a cloning vector that was cleaved with complementary restriction enzymes. It uses ligase to chemically join the input genetic material and the cloning vector to create a recombinant vector.
http://purl.obolibrary.org/obo/OBI_0000739	Student's t-test	http://purl.obolibrary.org/obo/OBI_0000673	statistical hypothesis test		Studen't t-test is a data transformation with the objective of a statistical hypothesis test in which the test statistic has a Student's t distribution if the null hypothesis is true. It is applied when the population is assumed to be normally distributed but the sample sizes are small enough that the statistic on which inference is based is not normally distributed because it relies on an uncertain estimate of standard deviation rather than on a precisely known value.
http://purl.obolibrary.org/obo/OBI_0000740	material sample role	http://purl.obolibrary.org/obo/OBI_0000112	specimen role		A material sample role is a specimen role borne by a material entity that is the output of a material sampling process.
http://purl.obolibrary.org/obo/OBI_0000741	topologically preserved clustered data set	http://purl.obolibrary.org/obo/OBI_0000648	clustered data set		A clustered data set in which the topology, i.e. the spatial properties between data points, is preserved from the original input data from which it was derived.
http://purl.obolibrary.org/obo/OBI_0000742	nucleic acid restriction enzyme digest	http://purl.obolibrary.org/obo/CHEBI_33696	nucleic acid		A nucleic acid digest is a material that is the output of a process in which nucleic acids are combined with a restriction enzyme resulting in digested fragments with defined ends based on the enzymes cleavage site
http://purl.obolibrary.org/obo/OBI_0000743	immune response assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that determines information about an immune response
http://purl.obolibrary.org/obo/OBI_0000748	bisulfite sequencing assay	http://purl.obolibrary.org/obo/OBI_0000634	DNA methylation profiling assay		A DNA methylation profiling assay which determines the methylation status of genomic DNA using DNA sequencing techniques preceded by a bisulfite based chemical modification of genomic DNA at CpG island location.
http://purl.obolibrary.org/obo/OBI_0000784	anticoagulant-containing test tube	http://purl.obolibrary.org/obo/OBI_0000836	test tube		A 'blue top' test tube that contains anticoagulant for storing blood specimens'
http://purl.obolibrary.org/obo/OBI_0000788	fluorescently labeled MHC multimer	http://purl.obolibrary.org/obo/OBI_0001936	molecular-labeled material		A complex of two or more linked MHC molecules including a fluorescent label that can be loaded with a ligand, and is used in flow cytometry assay to bind to T cell receptors of T cells specific for the ligand
http://purl.obolibrary.org/obo/OBI_0000789	survival rate	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement data that represents the percentage of people or animals in a study or treatment group who are alive for a given period of time after diagnosis or initiation of monitoring.
http://purl.obolibrary.org/obo/OBI_0000790	recombinant BAC cloning	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		Recombinant BAC cloning is a  process with the objective to insert genetic material into an F plasmid based bacterial artificial chromosome for future replication of the inserted material
http://purl.obolibrary.org/obo/OBI_0000792	statistical model validation	http://purl.obolibrary.org/obo/OBI_0200171	partitioning data transformation		A data transformation which assesses how the results of a statistical analysis will generalize to an independent data set.
http://purl.obolibrary.org/obo/OBI_0000793	double blind study execution	http://purl.obolibrary.org/obo/OBI_0000822	single blind study execution		A double blind study execution is defined as any study execution in which neither the subjects nor the investigators are informed of which study arm the subjects are part of during the portion of the trial when the subjects are being treated
http://purl.obolibrary.org/obo/OBI_0000797	obsolete_primary structure of protein	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		The primary structure of a protein that is completely defined by the set of its amino acid residue parts and the linear order induced by the peptide bonds that hold them together
http://purl.obolibrary.org/obo/OBI_0000798	capsule shell	http://purl.obolibrary.org/obo/BFO_0000040	material entity		a small rounded gelatinous container
http://purl.obolibrary.org/obo/OBI_0000799	recombinant phage cloning	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		Recombinant phage cloning is the process of using a phage plus some insert nucleic acid for the purposes of amplification of the insert material achieved by phage assembly in vitro.
http://purl.obolibrary.org/obo/OBI_0000800	cross linking	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A process in which bonds are created that link one polymer to another
http://purl.obolibrary.org/obo/OBI_0000802	prothrombin time assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the prothrombin ratio, which is the prothrombin time for a patient, divided by the result for control plasma. Most commonly the test is preformed using blood plasma. Blood is drawn into a test tube containing liquid citrate, which acts as an anticoagulant. An excess of calcium is added to enable the blood to clot again.Tissue factor (also known as factor III or thromboplastin) is added, and the time the sample takes to clot is measured optically as the prothrombin time, which is compared to a control sample.
http://purl.obolibrary.org/obo/OBI_0000803	denaturing	http://purl.obolibrary.org/obo/OBI_0000094	material processing		Is a process in which the tertiary or secondary structure of a polymer is disrupted
http://purl.obolibrary.org/obo/OBI_0000804	informing investigator of subject study arm	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to make the investigator aware of which study arm a patient is participating in.
http://purl.obolibrary.org/obo/OBI_0000806	material maintenance objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification maintains some or all of the qualities of a material over time.
http://purl.obolibrary.org/obo/OBI_0000808	spectrolyse heparin antifactor-Xa assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that quantitatively measures heparin in human plasma using Factor Xa and Antithrombin III in excess, where the rate of Factor Xa inhibition is directly proportional to the heparin concentration. The residual Factor Xa activity, measured with a Factor Xa-specific chromogenic substrate, is inversely proportional to the heparin concentration.
http://purl.obolibrary.org/obo/OBI_0000809	amplified DNA	http://purl.obolibrary.org/obo/CHEBI_16991	deoxyribonucleic acid		DNA that has been produced in an enzymatic amplification process
http://purl.obolibrary.org/obo/OBI_0000810	informed consent process	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to inform a person or their legal representative of legally and ethically relevant facts about a process that the person in question is asked to participate in, and which results in a documented decision as to whether the person in question will participate.
http://purl.obolibrary.org/obo/OBI_0000811	primary structure of DNA macromolecule	http://purl.obolibrary.org/obo/SO_0000001	region		a quality of a DNA molecule that inheres in its bearer due to the order of its DNA nucleotide residues.
http://purl.obolibrary.org/obo/OBI_0000812	measuring neural activity in the caudate nucleus assay	http://purl.obolibrary.org/obo/OBI_0000454	extracellular electrophysiology recording assay		An assay that measures neural activity in the caudate nucleus
http://purl.obolibrary.org/obo/OBI_0000813	to be treated with active ingredient role	http://purl.obolibrary.org/obo/OBI_0000097	participant under investigation role		A study subject role which begins to exist when a subject is assigned to be one of those who will receive active ingredient, and is realized in a study execution in which they receive the active ingredient
http://purl.obolibrary.org/obo/OBI_0000814	guar gum	http://purl.obolibrary.org/obo/BFO_0000040	material entity		Guar gum, also called guaran, is a galactomannan. It is primarily the ground endosperm of guar beans. The guar seeds are dehusked, milled and screened to obtain the guar gum.[1] It is typically produced as a free flowing, pale, off-white colored, coarse to fine ground powder.
http://purl.obolibrary.org/obo/OBI_0000815	Berichrom(r) Antithrombin III (A) Kit	http://purl.obolibrary.org/obo/OBI_0000047	processed material		For the chromogenic determination of antithrombin III. Autoanalyzer method for undiluted samples. For the quantitative chromogenic determination of the functional activity of antithrombin III in plasma on autoanalyzers for the diagnosis of diminished AT III synthesis, increased consumption, and for monitoring substitution therapy. Berichrom(r) Antithrombin III (A) is used for the rapid determination of the physiologically active antithrombin III and permits the diagnosis of congenital and acquired antithrombin III deficiency, a condition frequently associated with an increased risk of thrombosis. Acquired antithrombin III deficiencies frequently occur due to consumption following major operations or due to disseminated intravascular coagulation (DIC) in cases of septicaemia, nephroses, liver parenchymal damage (hepatitis, drug intoxication, alcoholism) and estrogen-containing contraceptives. The test permits early detection of patients at increased risk for thrombosis. Kit contains: 6 x for 5.0 mL Thrombin (bovine), 3 x for 3.0 mL Substrate Reagent, 1 x 30.0 mL Buffer Solution
http://purl.obolibrary.org/obo/OBI_0000817	fucoidan	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Fucoidan is a sulfated polysaccharide (MW: average 20,000) found mainly in various species of brown seaweed such as kombu, limu moui,bladderwrack, wakame, mozuku, and hijiki (variant forms of fucoidan have also been found in animal species, including the sea cucumber).
http://purl.obolibrary.org/obo/OBI_0000818	calibration	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to establish the relationship between data produced by a measurement device and physical qualities. This is done by using the measurement device under defined conditions, and either tuning it to adjust the measured output, or record the output and use it as a reference in future measurements.
http://purl.obolibrary.org/obo/OBI_0000819	anticoagulant tube storage of blood specimen	http://purl.obolibrary.org/obo/OBI_0302893	storage		Storage of a blood specimen in a tube with anticoagulant
http://purl.obolibrary.org/obo/OBI_0000821	filled capsule	http://purl.obolibrary.org/obo/OBI_0000827	pill		A pill in the form of a small rounded gelatinous container with medicine inside.
http://purl.obolibrary.org/obo/OBI_0000822	single blind study execution	http://purl.obolibrary.org/obo/OBI_0000826	treatment portion of study execution		A single blind study execution is defined as any study execution in which the subjects are not informed of which study arm they are part of during the portion of the trial when the subjects are being treated
http://purl.obolibrary.org/obo/OBI_0000823	thrombin time assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the time between the addition of the thrombin and the clot formation in plasma.
http://purl.obolibrary.org/obo/OBI_0000824	recombinant YAC cloning	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		Recombinant YAC cloning is a  process with the objective to insert genetic material into a yeast artificial chromosome vector for future replication of the inserted material
http://purl.obolibrary.org/obo/OBI_0000825	to be treated with placebo role	http://purl.obolibrary.org/obo/OBI_0000097	participant under investigation role		A study subject role which begins to exist when a subject is assigned to be one of those who will receive a placebo, and realized in a study execution in which they receive the placebo
http://purl.obolibrary.org/obo/OBI_0000826	treatment portion of study execution	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process, part of a study design execution, during which the treatment of subjects is ongoing
http://purl.obolibrary.org/obo/OBI_0000827	pill	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A dose of medicine or placebo in the form of a small pellet.
http://purl.obolibrary.org/obo/OBI_0000828	research organization	http://purl.obolibrary.org/obo/OBI_0000245	organization		An organization formed with a goal to have its members conduct investigations
http://purl.obolibrary.org/obo/OBI_0000830	obsolete_primary structure of sequence macromolecule	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A quality inhering in a molecule that is completely defined by the linear sequence of a set of residues which are connected by directional, linear bonds
http://purl.obolibrary.org/obo/OBI_0000831	DNA residue methylation	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		a quality of a DNA residue that has a methyl group attached to it
http://purl.obolibrary.org/obo/OBI_0000832	measurement device	http://purl.obolibrary.org/obo/OBI_0000968	device		A device in which a measure function inheres.
http://purl.obolibrary.org/obo/OBI_0000834	high molecular weight DNA extract	http://purl.obolibrary.org/obo/OBI_0001051	DNA extract		The output of an extraction process in which DNA molecules above a molecular weight cutoff are purified in order to exclude DNA from organellas.
http://purl.obolibrary.org/obo/OBI_0000835	manufacturer	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A person or organization that has a manufacturer role.
http://purl.obolibrary.org/obo/OBI_0000837	oral ingestion of pill	http://purl.obolibrary.org/obo/OBI_0000952	oral administration		An adding a material entity to target with the entity is a pill and the target is the mouth
http://purl.obolibrary.org/obo/OBI_0000838	material maintenance	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to maintain some or all of the characteristics of an input material over time.
http://purl.obolibrary.org/obo/OBI_0000839	labeled oligonucleotide	http://purl.obolibrary.org/obo/OBI_0001936	molecular-labeled material		a labeled oligonucleotide is a short nucleic acid which underwent a labeling process resulting in a radioactive isotope such as P32 or P33 added to its backbone for instance by end labeling with polynucleotide kinase which added radiolabeled ATP to the 5' end of oligonucleotide
http://purl.obolibrary.org/obo/OBI_0000840	unblinding process	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process that is the part of the study execution in which the subjects are told what study arm they are in and in which the investigators are told which subjects are in which trials.
http://purl.obolibrary.org/obo/OBI_0000841	subject agrees they understand informed consent document	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which a subject receives an informed consent document and agrees that they have understood it.
http://purl.obolibrary.org/obo/OBI_0000842	informing subject of study arm	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to make the subject aware of which study arm they are participating in.
http://purl.obolibrary.org/obo/OBI_0000843	Sysmex CA-6000 Coagulation Analyzer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		The Sysmex CA-6000 automated coagulation analyzer is a random access instrument that is capable of performing 20 clot-based and chromogenic assays
http://purl.obolibrary.org/obo/OBI_0000844	obsolete hospital	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A medical organization at which sick or injured people are given clinical care
http://purl.obolibrary.org/obo/OBI_0000845	primary structure of RNA molecule	http://purl.obolibrary.org/obo/SO_0000001	region		The primary structure of an RNA molecule that is completely defined by the set of its nucleic residue parts and the linear order induced by the peptide bonds that hold them together
http://purl.obolibrary.org/obo/OBI_0000847	test substance role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role born by a material entity and realized in a process where the substance is used as specified as the independent variable for an investigation
http://purl.obolibrary.org/obo/OBI_0000848	polyA RNA extraction	http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction		A RNA extraction process typically involving the use of poly dT oligomers in which the desired output material is polyA RNA.
http://purl.obolibrary.org/obo/OBI_0000849	organellar RNA extraction	http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction		A RNA extraction process in which the desired output material is RNA in the organelle(s).
http://purl.obolibrary.org/obo/OBI_0000852	record of missing knowledge	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity created to indicate that information about something is not available to the person recording it.
http://purl.obolibrary.org/obo/OBI_0000854	western blot assay	http://purl.obolibrary.org/obo/OBI_0001978	immunoblot assay		An analyte assay that detects specific peptides in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with_ antibodies specific to the analyte molecules.
http://purl.obolibrary.org/obo/OBI_0000855	total RNA extraction	http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction		A RNA extraction process in which total cellular and organelle RNA are extracted.
http://purl.obolibrary.org/obo/OBI_0000856	obsolete intracellular material detection by flow cytometry assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An assay in which the presence of a material inside a cell is measured by permeabilizing the cell membrane to allow entry of specific antibodies, and counting the stained cells using a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0000857	complementary nucleotide probe role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role played by a nucleic acid molecule that is used in a planned process for its ability to bind a nucleic acid molecules with complementary nucleotide sequence
http://purl.obolibrary.org/obo/OBI_0000858	record of unknown sex	http://purl.obolibrary.org/obo/OBI_0000852	record of missing knowledge		a record indicating that the biological sex of an organism is not known.
http://purl.obolibrary.org/obo/OBI_0000859	cytoplasmic RNA extraction	http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction		A RNA extraction process in which the desired output material is RNA in the cytoplasm.
http://purl.obolibrary.org/obo/OBI_0000861	Likelihood-ratio test	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Likelihood-ratio is a data transformation which tests whether there is evidence of the need to move from a simple model to a more complicated one (where the simple model is nested within the complicated one); tests of the goodness-of-fit between two models.
http://purl.obolibrary.org/obo/OBI_0000862	nuclear RNA extract	http://purl.obolibrary.org/obo/OBI_0000880	RNA extract		A RNA extract that is the output of an extraction process in which RNA molecules found in the nucleus, including mRNA precursors (pre-mRNA), are extracted.
http://purl.obolibrary.org/obo/OBI_0000867	establishing cancer cell line	http://purl.obolibrary.org/obo/OBI_0001867	establishing cell line		is a planned process in which the objective is to generate a cell line from a natural population of cancer cells which are already immortal
http://purl.obolibrary.org/obo/OBI_0000868	pattern matching objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A pattern matching objective aims to detect the presence of the constituents of a given pattern. In contrast to pattern recognition, the pattern is rigidly specified. Patterns are typicall sequences or trees.
http://purl.obolibrary.org/obo/OBI_0000869	polyA RNA extract	http://purl.obolibrary.org/obo/OBI_0000880	RNA extract		A RNA extract that is the output of an extraction process in which RNA molecules with poly A tail at its 3' end are purified.
http://purl.obolibrary.org/obo/OBI_0000870	single-nucleotide-resolution nucleic acid structure mapping assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that provides information about the secondary structure of nucleic acids using chemical or enzymatic probing to establish the extent of base-pairing or solvent accessiblity.
http://purl.obolibrary.org/obo/OBI_0000873	pre-mortem specimen	http://purl.obolibrary.org/obo/OBI_0001506	specimen with pre- or post-mortem status		a specimen that was taken from a live organism
http://purl.obolibrary.org/obo/OBI_0000874	detection of specific nucleic acid polymers with complementary probes	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay in which a specified input material (the evaluant) is examined for the presence or quantity of specified nucleic acid polymers, which are identified based on the use of complementary nucleic acid probes.
http://purl.obolibrary.org/obo/OBI_0000876	cytoplasmic RNA extract	http://purl.obolibrary.org/obo/OBI_0000880	RNA extract		A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted.
http://purl.obolibrary.org/obo/OBI_0000879	random primed DNA labeling	http://purl.obolibrary.org/obo/OBI_0600038	addition of molecular label		a labeling in which random primers are used to uniformly label input DNA
http://purl.obolibrary.org/obo/OBI_0000880	RNA extract	http://purl.obolibrary.org/obo/OBI_0001010	nucleic acid extract		an extract which is the output of an extraction process in which RNA molecules are isolated from a specimen.
http://purl.obolibrary.org/obo/OBI_0000882	cell-cell killing assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that monitors a cell population to track how many are killed by other cells.
http://purl.obolibrary.org/obo/OBI_0000883	in vivo cell killing assay	http://purl.obolibrary.org/obo/OBI_0000882	cell-cell killing assay		A cell killing assay that measures if and how many target cells are killed within an organism.
http://purl.obolibrary.org/obo/OBI_0000885	secondary structure of sequence macromolecule	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		A quality inhering in a molecule that refers to general three-dimensional form of local segments of biopolymers such as proteins and nucleic acids (DNA/RNA). It does not, however, describe specific atomic positions in three-dimensional space, which are considered to be tertiary structure.
Secondary structure was introduced by Kaj Ulrik Linderstrøm-Lang in the 1952 Lane medical lectures at Stanford.
http://purl.obolibrary.org/obo/OBI_0000888	nuclear RNA extraction	http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction		A RNA extraction process in which the desired output material is RNA in the nucleus.
http://purl.obolibrary.org/obo/OBI_0000889	survival curve	http://purl.obolibrary.org/obo/IAO_0000573	line graph		A survival curve is a report graph which is a graphical representation of data where the percentage of survival is plotted as a function of time.
http://purl.obolibrary.org/obo/OBI_0000891	cell proliferation assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay which measures the degreee to which input cells are replicating.
http://purl.obolibrary.org/obo/OBI_0000894	protein extract	http://purl.obolibrary.org/obo/OBI_0000423	extract		a protein extract is the output of an extraction process from tissues or cell cultures resulting in a solution of cellular and/or organellar proteins in buffer solution used to prevent degradation,
http://purl.obolibrary.org/obo/OBI_0000895	total RNA extract	http://purl.obolibrary.org/obo/OBI_0000880	RNA extract		A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen.
http://purl.obolibrary.org/obo/OBI_0000896	secondary structure of RNA molecule	http://purl.obolibrary.org/obo/OBI_0000885	secondary structure of sequence macromolecule		
http://purl.obolibrary.org/obo/OBI_0000897	DEPC structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing		A single-nucleotide-resolution nucleic acid structure mapping assay which determines nucleic acid secondary structure at a nucleotide resolution scale using DEPC as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0000899	organellar RNA extract	http://purl.obolibrary.org/obo/OBI_0000880	RNA extract		A RNA extract that is the output of an extraction process in which RNA molecules found in an organelle, e.g., mitochondrion, ER, or chloroplast, excluding the nucleus, are extracted.
http://purl.obolibrary.org/obo/OBI_0000902	post mortem specimen	http://purl.obolibrary.org/obo/OBI_0001506	specimen with pre- or post-mortem status		a specimen that was taken from a dead organism
http://purl.obolibrary.org/obo/OBI_0000903	in vitro cell killing assay	http://purl.obolibrary.org/obo/OBI_0003587	cell culture assay		A cell killing assay that measures if and how many target cells are actively killed by other cells in a cell culture.
http://purl.obolibrary.org/obo/OBI_0000904	reporter cell line analyte detection bioassay	http://purl.obolibrary.org/obo/OBI_0003587	cell culture assay		An analyte assay in which a cell line whose growth is known to be affected by the presence of a specific type of material (the anlyte) is cultured in the presence of an input material (the evaluant) in order to detect presence of the analyte in the evaluant.
http://purl.obolibrary.org/obo/OBI_0000905	sequence feature annotation	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		Information about a sequence region
http://purl.obolibrary.org/obo/OBI_0000907	supplying	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to provide material entities to be used in an investigation.
http://purl.obolibrary.org/obo/OBI_0000908	labeled DNA extract	http://purl.obolibrary.org/obo/OBI_0001143	labeled nucleic acid extract		a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments.
http://purl.obolibrary.org/obo/OBI_0000909	cloacal specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium.
http://purl.obolibrary.org/obo/OBI_0000910	radio immuno assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay in which a radioactive labeled antigen or antibody is used to determine the interaction between an antigen and its receptor. This can be used to detect the presence of an antigen of interest in an input sample or determine the specificity of an input antibody.
http://purl.obolibrary.org/obo/OBI_0000912	X-ray crystallography 3D molecular structure determination assay	http://purl.obolibrary.org/obo/OBI_0003117	3D molecular structure determination assay		A 3D molecular structure determination assay in which the diffraction of pattern of X-ray beams in a crystal of purified material entities is used to resolve the 3-dimensional structure of the material entity of interest.
http://purl.obolibrary.org/obo/OBI_0000913	promoter activity detection by reporter gene assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay in which the activity of a promoter in a cell is monitored by using a reporter gene that was inserted in a genomic location under control of the promoter and whose expression can be easily detected based on qualities or functions of the gene.
http://purl.obolibrary.org/obo/OBI_0000914	nasopharyngeal aspirate specimen	http://purl.obolibrary.org/obo/OBI_2000007	nasopharynx specimen		A specimen which derives from nasopharyngeal mucosa after aspiration.
http://purl.obolibrary.org/obo/OBI_0000915	freezing storage	http://purl.obolibrary.org/obo/OBI_0302893	storage		A storage process in temperature that maintenance the frozen status of the stored entities.
http://purl.obolibrary.org/obo/OBI_0000917	nasal swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination.
http://purl.obolibrary.org/obo/OBI_0000921	labeled RNA extract	http://purl.obolibrary.org/obo/OBI_0001143	labeled nucleic acid extract		a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments.
http://purl.obolibrary.org/obo/OBI_0000922	frozen specimen	http://purl.obolibrary.org/obo/OBI_0001472	specimen with known storage state		A specimen that has been frozen in order to store it.
http://purl.obolibrary.org/obo/OBI_0000923	surface plasmon resonance binding assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay that uses the detection of electromagnetic waves in a surface to detect material entities adsorbed to the surface, which change the local optical index of refraction.
http://purl.obolibrary.org/obo/OBI_0000924	labeled specimen	http://purl.obolibrary.org/obo/OBI_0001936	molecular-labeled material		A specimen  that has been modified in order to be able to detect it in future experiments
http://purl.obolibrary.org/obo/OBI_0000925	infectious agent	http://purl.obolibrary.org/obo/OBI_0100026	organism		is a material entity bearing the disposition to infect an organism
http://purl.obolibrary.org/obo/OBI_0000927	lyophilization storage	http://purl.obolibrary.org/obo/OBI_0302893	storage		a storage process with input material entity and output freeze dried material for long time storage
http://purl.obolibrary.org/obo/OBI_0000928	material combination function	http://purl.obolibrary.org/obo/BFO_0000034	function		A material separation function is a function that decreases the resolution between two or more material entities.
http://purl.obolibrary.org/obo/OBI_0000929	obsolete_training service provider role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a service provider role which is realized by a servicer provider organization performing some training
http://purl.obolibrary.org/obo/OBI_0000931	study intervention	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process that is the part of the execution of an intervention design study which is varied between two or more subjects in the study.
http://purl.obolibrary.org/obo/OBI_0000932	material separation device	http://purl.obolibrary.org/obo/OBI_0000968	device		A device with a separation function realized in a planed process
http://purl.obolibrary.org/obo/OBI_0000934	intramuscular injection	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		is the injection of a material entity (bearing the administered substance role) into the muscle (bearing the target role) of an organism using a syringe
http://purl.obolibrary.org/obo/OBI_0000935	micromanipulator	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to physically interact with a sample under a microscope, where a level of precision of movement is necessary that cannot be achieved by the unaided human hand.
http://purl.obolibrary.org/obo/OBI_0000936	obsolete_material access provider role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a service provider role which is realized by a servicer provider organization performing access to some material
http://purl.obolibrary.org/obo/OBI_0000939	training process	http://purl.obolibrary.org/obo/OBI_0000011	planned process		a process that achieves a training objective
http://purl.obolibrary.org/obo/OBI_0000940	optical microscope	http://purl.obolibrary.org/obo/OBI_0400169	microscope		A microscope that produces an image of an object by targeting it with an electro-magnetic beam in the visible frequency range
http://purl.obolibrary.org/obo/OBI_0000941	service consumer role	http://purl.obolibrary.org/obo/BFO_0000023	role		a role which inheres in a person who uses a service
http://purl.obolibrary.org/obo/OBI_0000942	intradermal injection	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		is the injection of a material entity (bearing the administered substance role) into the dermis (bearing the target role) of an organism using a syringe
http://purl.obolibrary.org/obo/OBI_0000943	chemical cleavage	http://purl.obolibrary.org/obo/OBI_0000094	material processing		chemical cleavage is a protocol application relying on a chemical compound to cause the fragmentation of an input material that is susceptible to that chemical agent
http://purl.obolibrary.org/obo/OBI_0000945	vibration isolation table	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device  that supports another device such as a precision instrument by isolating it from vibration that is transmitted from the floor.
http://purl.obolibrary.org/obo/OBI_0000946	sterilization function	http://purl.obolibrary.org/obo/BFO_0000034	function		a function to remove viable organisms from an input material
http://purl.obolibrary.org/obo/OBI_0000947	service provider role	http://purl.obolibrary.org/obo/BFO_0000023	role		is a role which inheres in a person or organization and is realized in in a planned process which provides access to training, materials or execution of protocols for an organization or person
http://purl.obolibrary.org/obo/OBI_0000948	oscilloscope	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device that measures and displayes signal voltages, usually as a two-dimensional graph of one or more electrical potential differences (vertical axis) plotted as a function of time or of some other voltage (horizontal axis).
http://purl.obolibrary.org/obo/OBI_0000949	accessed material role	http://purl.obolibrary.org/obo/BFO_0000023	role		is realized in a planned process where the bearer participates
http://purl.obolibrary.org/obo/OBI_0000950	paraffin specimen	http://purl.obolibrary.org/obo/OBI_0001472	specimen with known storage state		a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin
http://purl.obolibrary.org/obo/OBI_0000951	compound treatment design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		an intervention design in which the treatment is the administration of a compound
http://purl.obolibrary.org/obo/OBI_0000952	oral administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administering substance in vivo into the mouth of an organism
http://purl.obolibrary.org/obo/OBI_0000953	processed specimen	http://purl.obolibrary.org/obo/OBI_0100051	specimen		A specimen that has been intentionally physically modified.
http://purl.obolibrary.org/obo/OBI_0000954	subcutaneous injection	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		is the injection of a material entity (bearing the administered substance role) into the hypodermis (bearing the target role) of an organism using a syringe
http://purl.obolibrary.org/obo/OBI_0000955	electrode puller	http://purl.obolibrary.org/obo/OBI_0000968	device		A device used in the first step in making electrodes, that applies constant tension on a glass capillary tube and eventually breaks it while heating it; this produces a very fine point on the capillary tube.
http://purl.obolibrary.org/obo/OBI_0000957	self reported handedness assessment	http://purl.obolibrary.org/obo/OBI_0000944	handedness assay		An assay where a person makes a statement that indicates what handedness he has from a choice of different categories.
http://purl.obolibrary.org/obo/OBI_0000959	vibrotome	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A preparation device that uses a vibrating razor blade to cut through tissue.
http://purl.obolibrary.org/obo/OBI_0000960	reagent application function	http://purl.obolibrary.org/obo/BFO_0000034	function		A function that is realized when a reagent is automatically added to some research material.
http://purl.obolibrary.org/obo/OBI_0000961	addition of molecular tracer function	http://purl.obolibrary.org/obo/OBI_0000960	reagent application function		A reagent application function that is realized when a molecular tracer, such as an antibody or probe is automatically transferred to a biological specimen.
http://purl.obolibrary.org/obo/OBI_0000962	training objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification which is fulfilled by the provision of some training.
http://purl.obolibrary.org/obo/OBI_0000963	categorical label	http://purl.obolibrary.org/obo/IAO_0000009	datum label		A label that is part of a categorical datum and that indicates the value of the data item on the categorical scale.
http://purl.obolibrary.org/obo/OBI_0000964	in live cell assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay in which a measurement is made by observing entities located in a live cell.
http://purl.obolibrary.org/obo/OBI_0000965	lyophilized specimen	http://purl.obolibrary.org/obo/OBI_0001472	specimen with known storage state		a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage.
http://purl.obolibrary.org/obo/OBI_0000967	container	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that can be used to restrict the location of material entities over time
http://purl.obolibrary.org/obo/OBI_0000971	fresh specimen	http://purl.obolibrary.org/obo/OBI_0001472	specimen with known storage state		a specimen that is output of a specimen creation process used for an investigation without storage.
http://purl.obolibrary.org/obo/OBI_0000972	obsolete_electrically powered device	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a processed material created to have a function and which requires electrical power to execute
http://purl.obolibrary.org/obo/OBI_0000973	sequence data	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum that representing the primary structure of a macromolecule(it's sequence) sometimes associated with an indicator of confidence of that measurement.
http://purl.obolibrary.org/obo/OBI_0000975	cell-cell binding detection by flow cytometry assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A binding assay which uses a flow cytometer to detect pairs of cells that are bound to each other by staining them with different fluorescent labels.
http://purl.obolibrary.org/obo/OBI_0000976	handedness categorical measurement datum	http://purl.obolibrary.org/obo/OBI_0000938	categorical measurement datum		A datum used to record the answer to a self assessment of whether a person uses their left hand, right hand primarily or each hand equally
http://purl.obolibrary.org/obo/OBI_0000977	paraffin storage	http://purl.obolibrary.org/obo/OBI_0302893	storage		a storage process with input organism or anatomical entity and paraffin and output material embedded in paraffin for long term storage
http://purl.obolibrary.org/obo/OBI_0000978	in container assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay in which a measurement is made by observing entities located in a container.
http://purl.obolibrary.org/obo/OBI_0000980	obsolete_protocol service provider role	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a service provider role which is realized by a servicer provider organization performing a protocol execution
http://purl.obolibrary.org/obo/OBI_0000981	agar stab specimen	http://purl.obolibrary.org/obo/OBI_0001472	specimen with known storage state		a specimen that is output of a process that cell culture inoculated into agar for long term storage.
http://purl.obolibrary.org/obo/OBI_0000983	intranasal mucosal administration	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		The administration of a substance into the intranasal mucosis of an organism
http://purl.obolibrary.org/obo/OBI_0000984	dose	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum that measures the quantity of something that may be administered to an organism or that an organism may be exposed to. Quantities of nutrients, drugs, vaccines and toxins are referred to as doses.
http://purl.obolibrary.org/obo/OBI_0000985	growth condition intervention design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		A study design in which the independent variable is the environmental condition in which the specimen is growing
http://purl.obolibrary.org/obo/OBI_0000986	obsolete_DNA sequencing training service	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A training process with the objective to provide a trainee with the skill to run DNA sequencing experiments
http://purl.obolibrary.org/obo/OBI_0000988	obsolete performing a diagnosis	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		The interpretation of the information available about bodily features (clinical picture) of a patient resulting in a diagnosis
http://purl.obolibrary.org/obo/OBI_0000989	PCR instrument	http://purl.obolibrary.org/obo/OBI_0400116	thermal cycler		A device that is used to amplify a single or few copies of a piece of DNA across several orders of magnitude, generating thousands to millions of copies of a particular DNA sequence.
http://purl.obolibrary.org/obo/OBI_0000990	electron microscope	http://purl.obolibrary.org/obo/OBI_0400169	microscope		A microscope that produces an image of an object by targeting it with an electron beam
http://purl.obolibrary.org/obo/OBI_0000991	Edinburgh score	http://purl.obolibrary.org/obo/OBI_0000970	scalar score from composite inputs		A score that measures the dominance of a person's right or left hand in everyday activities.
http://purl.obolibrary.org/obo/OBI_0000992	DNA sequencing service	http://purl.obolibrary.org/obo/OBI_0001904	sequencing service		A DNA sequencing  process provided as a service - which is the realization of some DNA sequencing in which the service provider role is realized.
http://purl.obolibrary.org/obo/OBI_0000993	service provision objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective which is fulfilled by the provision of some service e.g. a training service
http://purl.obolibrary.org/obo/OBI_0000994	intravenous injection	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		is the injection of a material entity (bearing the administered substance role) into the vein (bearing the target role) of an organism using a syringe
http://purl.obolibrary.org/obo/OBI_0000995	administration of material to specimen	http://purl.obolibrary.org/obo/OBI_0000274	adding a material entity into a target		The directed combination of a material entity with a specimen.
http://purl.obolibrary.org/obo/OBI_0000996	device creation objective	http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective		an objective which aims to create a device with a specified function
http://purl.obolibrary.org/obo/OBI_0000997	growth environment	http://purl.obolibrary.org/obo/BFO_0000040	material entity		The collection of material entities and their qualities that are located near a live organism, tissue or cell and can influence its growth.
http://purl.obolibrary.org/obo/OBI_0001000	questionnaire	http://purl.obolibrary.org/obo/IAO_0000310	document		A document with a set of printed or written questions with a choice of answers, devised for the purposes of a survey or statistical study.
http://purl.obolibrary.org/obo/OBI_0001001	Edinburgh handedness assay	http://purl.obolibrary.org/obo/OBI_0000944	handedness assay		An assay that uses a set of questions (the Edinburgh Handedness inventory) to generate a score that can be used to assess the dominance of a person's right or left hand in everyday activities. The inventory can be used by an observer assessing the person, or by a person self-reporting hand use. The latter method tends to be less reliable due to a person over-attributing tasks to the dominant hand.
http://purl.obolibrary.org/obo/OBI_0001003	agar stab storage	http://purl.obolibrary.org/obo/OBI_0302893	storage		a storage process with input cell culture and agar and output agar stab for long time storage
http://purl.obolibrary.org/obo/OBI_0001009	obsolete_qualitative binding detection assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A binding assay where the specified output determines if two or more material entities do or do not have the disposition to form a complex above a threshold level of significance. The threshold can be defined through detection limits of the instrument, the use of experimental controls that establish what is considered significant binding, or a predefined cutoff based on what binding is considered significant in a certain context.
http://purl.obolibrary.org/obo/OBI_0001010	nucleic acid extract	http://purl.obolibrary.org/obo/OBI_0000953	processed specimen		An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen.
http://purl.obolibrary.org/obo/OBI_0001013	kethoxal structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing		A single-nucleotide-resolution nucleic acid structure mapping assay that determines nucleic acid secondary structure at nucleotide resolution scale using kethoxal as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001014	single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing	http://purl.obolibrary.org/obo/OBI_0000870	single-nucleotide-resolution nucleic acid structure mapping assay		A single-nucleotide-resolution nucleic acid structure mapping assay that determines structural information about the RNA species under study using proteins acting as enzymatic probes.
http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing	http://purl.obolibrary.org/obo/OBI_0000870	single-nucleotide-resolution nucleic acid structure mapping assay		A single-nucleotide-resolution nucleic acid structure mapping assay that determines structural information about the RNA species under study using small chemical compounds acting as chemical probes.
http://purl.obolibrary.org/obo/OBI_0001022	gene dosage assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures changes in phenotype due to increased or decreased dosage of a single allele of a gene.
http://purl.obolibrary.org/obo/OBI_0001025	binding constant determination assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay where the specified output is a binding constant
http://purl.obolibrary.org/obo/OBI_0001028	feature extraction	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A planed process with objective of obtaining quantified values from an image.
http://purl.obolibrary.org/obo/OBI_0001032	light emission device	http://purl.obolibrary.org/obo/OBI_0000968	device		A device which has a function to emit light.
http://purl.obolibrary.org/obo/OBI_0001033	perturbation device	http://purl.obolibrary.org/obo/OBI_0000968	device		A perturbation device is a device which is designed to perform a perturb function
http://purl.obolibrary.org/obo/OBI_0001034	environmental control device	http://purl.obolibrary.org/obo/OBI_0000968	device		An environmental control device is a device which has the function to control some aspect of the environment such as temperature, or humidity.
http://purl.obolibrary.org/obo/OBI_0001036	specimen fixation function	http://purl.obolibrary.org/obo/BFO_0000034	function		a function that allows specific identification of individual speciment from one another.
http://purl.obolibrary.org/obo/OBI_0001037	obsolete_specimen fixation function	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A specimen fixation function is a function that holds or fastens an entity in a fixed position.
http://purl.obolibrary.org/obo/OBI_0001038	Ruthenium structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing		A single-nucleotide-resolution nucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using Rhutenium as reagent and chemical probe
http://purl.obolibrary.org/obo/OBI_0001039	inline probing RNA structure mapping assay	http://purl.obolibrary.org/obo/OBI_0001017	single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing		A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at nucleotide resolution scale using intromolecular reactivity
http://purl.obolibrary.org/obo/OBI_0001040	current amplification function	http://purl.obolibrary.org/obo/BFO_0000034	function		A current amplification function is an amplification function that increases the amplitude of a current.
http://purl.obolibrary.org/obo/OBI_0001042	pump function	http://purl.obolibrary.org/obo/OBI_0000383	transfer function		a transfer unction where the transfer requires work to move the entity, often against a gradient.
http://purl.obolibrary.org/obo/OBI_0001043	cell transfer function	http://purl.obolibrary.org/obo/OBI_0000383	transfer function		is a transfer function that displaces cells from one place to another
http://purl.obolibrary.org/obo/OBI_0001044	angiograph	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device that records the patterns of pulse waves inside blood vessels.
http://purl.obolibrary.org/obo/OBI_0001045	capillary blotter	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to transfer nucleic acids from agarose gels onto a membrane, based on the movement of buffer from a reservoir through the gel and the blotting membrane to a stack of dry blotting paper by capillary force. The molecules are carried to the blotting membrane on which they are adsorbed.
http://purl.obolibrary.org/obo/OBI_0001046	bioreactor	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device or system that supports a biologically active environment.
http://purl.obolibrary.org/obo/OBI_0001047	pH meter	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device that is used to measure the pH (acidity or alkalinity) of a liquid.
http://purl.obolibrary.org/obo/OBI_0001048	digital camera	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		An image acquisition device that takes video or still photographs, or both, digitally by recording images via an electronic image sensor.
http://purl.obolibrary.org/obo/OBI_0001049	chip spotting device	http://purl.obolibrary.org/obo/OBI_0000968	device		A device for dropping and immobilizing a solution of biomolecules, for example, nucleic acids such as probe DNA, mRNA, and peptide nucleic acid (PNA), and proteins on a DNA microarray surface to manufacture a DNA microarray.
http://purl.obolibrary.org/obo/OBI_0001050	RNA extraction/purification instrument	http://purl.obolibrary.org/obo/OBI_0001114	nucleic acid extraction/purification instrument		A device that is used to isolate and collect RNA for subsequent molecular analysis.
http://purl.obolibrary.org/obo/OBI_0001051	DNA extract	http://purl.obolibrary.org/obo/OBI_0001010	nucleic acid extract		The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas.
http://purl.obolibrary.org/obo/OBI_0001052	two-photon laser/detector	http://purl.obolibrary.org/obo/OBI_0400065	light source		A light source used in fluorescence imaging that allows the imaging of living tissue up to a depth of 1 mm, based on the concept that two photons of low energy can excite a fluorophore in a quantum event, resulting in the emission of a fluorescence photon, typically at a higher energy than either of the two excitatory photons.
http://purl.obolibrary.org/obo/OBI_0001053	electrophoresis system	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A device that moves charged particles through a medium by using an electric field induced by electrodes.
http://purl.obolibrary.org/obo/OBI_0001054	PET synthesizer	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to produce targeted molecular pharmaceuticals for use in positron emission tomography.
http://purl.obolibrary.org/obo/OBI_0001055	spinning-disk confocal microscope	http://purl.obolibrary.org/obo/OBI_0001079	confocal microscope		A confocal microscope that uses a Nipkow disk, a mechanical, geometrically operating image scanning device.
http://purl.obolibrary.org/obo/OBI_0001056	DNA synthesizer	http://purl.obolibrary.org/obo/OBI_0400113	oligonucleotide synthesizer		An oligonucleotide synthesizer that is used to custom-build DNA molecules to contain a particular sequence of nucleotides.
http://purl.obolibrary.org/obo/OBI_0001057	high performance liquid chromatography instrument	http://purl.obolibrary.org/obo/OBI_0001139	liquid chromatography instrument		A liquid chromatography instrument that consists of a reservoir of mobile phase, a pump, an injector, a separation column, and a detector. The pump (rather than gravity) provides the higher pressure required to propel the mobile phase and analyte through the densely packed column.
http://purl.obolibrary.org/obo/OBI_0001058	microplate reader	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A measurement device that detects biological, chemical or physical events of samples in microtiter plates.
http://purl.obolibrary.org/obo/OBI_0001059	ELISA microplate reader	http://purl.obolibrary.org/obo/OBI_0001058	microplate reader		A microplate reader that is used for enzyme-linked immunosorbent assays (ELISA).
http://purl.obolibrary.org/obo/OBI_0001060	spot cutter	http://purl.obolibrary.org/obo/OBI_0000968	device		A robotic device that is used to excise spots from gels.
http://purl.obolibrary.org/obo/OBI_0001061	microwave synthesis system	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to apply microwave irradiation to chemical reactions.
http://purl.obolibrary.org/obo/OBI_0001062	densitometer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device that measures the degree of darkness (the optical density) of a photographic or semitransparent material or of a reflecting surface.
http://purl.obolibrary.org/obo/OBI_0001063	automatic staining machine	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to automatically stain tissue sections on slides or tissue specimens.
http://purl.obolibrary.org/obo/OBI_0001064	automatic tissue processor	http://purl.obolibrary.org/obo/OBI_0000968	device		A device for processing histological tissue having a tissue carrier basket suspended from a turntable overlying a plurality of beakers suspended from a carrier plate. The turntable is raised, indexed, and lowered by a suitable driving mechanism to move the tissue basket sequentially through the beakers. Timers can each be programmed to control the movement of the turntable to provide various different cycles for processing the tissue. Some of the beakers are received in individual thermal baths to heat and control the temperature of the substances received in the beakers for treating the tissue.
http://purl.obolibrary.org/obo/OBI_0001065	stereo microscope	http://purl.obolibrary.org/obo/OBI_0000940	optical microscope		An optical microscope that uses two separate optical paths with two objectives and two eyepieces to provide slightly different viewing angles to the left and right eyes.
http://purl.obolibrary.org/obo/OBI_0001066	top loading balance	http://purl.obolibrary.org/obo/OBI_0001135	balance		A balance that consists of a metal plate on which to place an object and a digital readout of the measurement of its mass.
http://purl.obolibrary.org/obo/OBI_0001067	perfusion station	http://purl.obolibrary.org/obo/OBI_0000968	device		A device or system in which perfusion units are integrated.
http://purl.obolibrary.org/obo/OBI_0001068	SPECT scanner	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		A nuclear medicine tomographic imaging device that uses gamma rays to provide 3D information, typically presented as cross-sectional slices through the specimen but with the ability to be freely reformatted or manipulated as required.
http://purl.obolibrary.org/obo/OBI_0001069	array manufacturer role	http://purl.obolibrary.org/obo/OBI_0000571	manufacturer role		a manufacturer role which is played by the person or organization that manufactured the array
http://purl.obolibrary.org/obo/OBI_0001070	scintillation counter	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device that is used to measure ionizing radiation.
http://purl.obolibrary.org/obo/OBI_0001071	programmable array microscope	http://purl.obolibrary.org/obo/OBI_0001079	confocal microscope		A confocal microscope that uses a programmable spatial light modulator for generating an arbitrary pattern of conjugate illumination and detection apertures.
http://purl.obolibrary.org/obo/OBI_0001072	cryostat	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device consisting of a vessel, similar in construction to a vacuum flask, that is used to maintain cold cryogenic temperatures. FIX THIS DEFINITION
http://purl.obolibrary.org/obo/OBI_0001073	microtome knife maker	http://purl.obolibrary.org/obo/OBI_0000968	device		A glass cutting and breaking device that is used to produce glass knives used in ultramicrotomy.
http://purl.obolibrary.org/obo/OBI_0001074	cryofixation device	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used for the fixation or stabilization of biological materials as the first step in specimen preparation for electron microscopy.
http://purl.obolibrary.org/obo/OBI_0001075	hybridization oven	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		A device that creates an appropriate environment for nucleic acid hybridization.
http://purl.obolibrary.org/obo/OBI_0001076	incubator shaker	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		An incubating device that provides shaking motion for biomedical applications (e.g., cell cultures).
http://purl.obolibrary.org/obo/OBI_0001077	small-animal image acquisition device	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		A device that is used to image small laboratory animals (e.g., rats and mice) in vivo.
http://purl.obolibrary.org/obo/OBI_0001078	infrared image acquisition device	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		An image acquisition device that is responsive to an infrared emissive target within a given field of view.
http://purl.obolibrary.org/obo/OBI_0001079	confocal microscope	http://purl.obolibrary.org/obo/OBI_0400169	microscope		A microscope that is used to increase micrograph contrast and/or reconstruct three-dimensional images by using a spatial pinhole to eliminate out-of-focus light in specimens that are thicker than the focal plane.
http://purl.obolibrary.org/obo/OBI_0001080	patch clamp device	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device used in electrophysiology that allows the study of single or multiple ion channels in cells.
http://purl.obolibrary.org/obo/OBI_0001081	gel imaging system	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		A device that is used to acquire images of laboratory gels.
http://purl.obolibrary.org/obo/OBI_0001082	protein separation apparatus	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A device that is used for the separation of proteins.
http://purl.obolibrary.org/obo/OBI_0001083	multichannel electronic pipette	http://purl.obolibrary.org/obo/OBI_0001118	multichannel pipette		A multichannel pipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense the aspirated volume or a series of aliquots in successive dispensing operations.
http://purl.obolibrary.org/obo/OBI_0001084	vitrification apparatus	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to effect the transition of a substance into a glass.
http://purl.obolibrary.org/obo/OBI_0001085	radiography instrument	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		An image acquisition device that uses ionizing electromagnetic radiation such as X-rays to view objects.
http://purl.obolibrary.org/obo/OBI_0001086	radiation measurement device	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device that consists of a radiosensitive detector and a means of recording the effects of radiation on the detector.
http://purl.obolibrary.org/obo/OBI_0001087	lyophilizer	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to freeze dry material.
http://purl.obolibrary.org/obo/OBI_0001088	tandem mass spectrometer	http://purl.obolibrary.org/obo/OBI_0000049	mass spectrometer		A mass spectrometer in which ions are subjected to two or more sequential stages of analysis (which may be separated spatially or temporally) according to the quotient mass/charge.
http://purl.obolibrary.org/obo/OBI_0001089	microhardness tester	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A hardness testing device that is used in light-optical microscopes.
http://purl.obolibrary.org/obo/OBI_0001090	multimode microplate reader	http://purl.obolibrary.org/obo/OBI_0001058	microplate reader		A microplate reader that can detect multiple types of absorbance, luminescence or fluorescence.
http://purl.obolibrary.org/obo/OBI_0001091	mechanical balance	http://purl.obolibrary.org/obo/OBI_0001135	balance		A balance that is used to compare the weights of two bodies, to determine the difference in mass (or weight).
http://purl.obolibrary.org/obo/OBI_0001092	computer cluster	http://purl.obolibrary.org/obo/OBI_0400107	computer		A group of linked computers, working together closely so that in many respects they form a single computer.
http://purl.obolibrary.org/obo/OBI_0001093	microtome knife sharpener	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to sharpen knives used in microtomy.
http://purl.obolibrary.org/obo/OBI_0001094	plate shaker	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that provides shaking motion for microplates.
http://purl.obolibrary.org/obo/OBI_0001095	coagulation analyzer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device for automatically analyzing blood coagulation in a clinical laboratory.
http://purl.obolibrary.org/obo/OBI_0001096	laser capture microdissection microscope	http://purl.obolibrary.org/obo/OBI_0400169	microscope		A microscope that uses low-energy laser beams and special transfer film to lift single cells from a tissue.
http://purl.obolibrary.org/obo/OBI_0001097	liquid extraction robot	http://purl.obolibrary.org/obo/OBI_0400112	liquid handler		A liquid handling device that provides automatic liquid extraction.
http://purl.obolibrary.org/obo/OBI_0001098	ultrasound machine	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		A device that is used to visualize subcutaneous body structures including tendons, muscles, joints, vessels and internal organs.
http://purl.obolibrary.org/obo/OBI_0001099	immunoblot scanner	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		A device that is used for the imaging of immunoblots.
http://purl.obolibrary.org/obo/OBI_0001100	microcentrifuge	http://purl.obolibrary.org/obo/OBI_0400106	centrifuge		A type of centrifuge that is designed for small tubes (0.2 ml to 2.0 ml), has a compact design, and has a small footprint.
http://purl.obolibrary.org/obo/OBI_0001101	electronic repeater pipette	http://purl.obolibrary.org/obo/OBI_0001128	micropipette		A micropipette that can be programmed by the user to aspirate a volume of liquid reagent or sample and dispense a series of aliquots in successive dispensing operations.
http://purl.obolibrary.org/obo/OBI_0001102	electron paramagnetic resonance spectrometer	http://purl.obolibrary.org/obo/OBI_0400115	spectrophotometer		An spectrophotometer that is used to investigate chemical species that have one or more unpaired electrons, such as organic and inorganic free radicals or inorganic complexes possessing a transition metal ion.
http://purl.obolibrary.org/obo/OBI_0001103	rocker	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that provides three-dimensional motion for biomedical applications (e.g., gel trays).
http://purl.obolibrary.org/obo/OBI_0001104	analytical balance	http://purl.obolibrary.org/obo/OBI_0001135	balance		A balance with weighing pan(s) inside a transparent enclosure that is used to measure mass to a very high degree of precision and accuracy.
http://purl.obolibrary.org/obo/OBI_0001105	scanning force microscope	http://purl.obolibrary.org/obo/OBI_0400169	microscope		A microscope that forms images of surfaces using a physical probe that scans the specimen.
http://purl.obolibrary.org/obo/OBI_0001106	pulsed-field gel electrophoresis system	http://purl.obolibrary.org/obo/OBI_0001121	gel electrophoresis system		A gel electrophoresis system in which the gel matrix is subjected to an electric field that periodically changes direction.
http://purl.obolibrary.org/obo/OBI_0001107	tissue embedding station	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to perform paraffin embedding of tissue specimens.
http://purl.obolibrary.org/obo/OBI_0001108	nucleic acid sequencer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		An device that is used to determine the order of nucleotides in nucleic acid sequences.
http://purl.obolibrary.org/obo/OBI_0001109	bead array reader	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		A device that is used to acquire and image bead array data.
http://purl.obolibrary.org/obo/OBI_0001110	real-time PCR machine	http://purl.obolibrary.org/obo/OBI_0000989	PCR instrument		An PCR instrument that enables both detection and quantification of one or more specific sequences in a DNA sample.
http://purl.obolibrary.org/obo/OBI_0001111	paraffin oven	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device that is used for the warming of paraffin embedding medium.
http://purl.obolibrary.org/obo/OBI_0001112	autoclave	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device that is used to sterilize equipment and supplies by subjecting them to high pressure steam at 121 C or more, typically for 15 to 20 minutes depending on the size of the load and the contents.
http://purl.obolibrary.org/obo/OBI_0001113	microplate washer	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to wash immunoassays in microwell strips and plates with professional accuracy. WHAT IS PROFESSIONAL ACCURACY??
http://purl.obolibrary.org/obo/OBI_0001114	nucleic acid extraction/purification instrument	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A device that is used to isolate and collect nucleic acids (DNA or RNA) for subsequent molecular analysis.
http://purl.obolibrary.org/obo/OBI_0001115	ELISA microplate washer	http://purl.obolibrary.org/obo/OBI_0001113	microplate washer		A microplate washer that is used for enzyme-linked immunosorbent assays (ELISA).
http://purl.obolibrary.org/obo/OBI_0001116	vacuum manifold	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used for the vacuum-driven processing of multiwell strips or plates, or spin columns. IS THIS AN INSTRUMENT? IS THE DEFINTION CORRECT - TO DISTRIBUTE PRESSURE EVENLY.
http://purl.obolibrary.org/obo/OBI_0001117	DNA extraction/purification instrument	http://purl.obolibrary.org/obo/OBI_0001114	nucleic acid extraction/purification instrument		A device that is used to isolate and collect DNA for subsequent molecular analysis.
http://purl.obolibrary.org/obo/OBI_0001118	multichannel pipette	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A pipetting system that has a plurality of tip fittings and is used for multi-well plate applications.
http://purl.obolibrary.org/obo/OBI_0001119	cell harvester	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to harvest cells from microplates and deposit samples on a filter mat. NOT AN INSTRUMENT?
http://purl.obolibrary.org/obo/OBI_0001120	portable fluorometer	http://purl.obolibrary.org/obo/OBI_0400143	fluorometer		A compact fluorometer that can be carried or moved with ease.
http://purl.obolibrary.org/obo/OBI_0001121	gel electrophoresis system	http://purl.obolibrary.org/obo/OBI_0001053	electrophoresis system		An electrophoresis system in which an electric field is applied to a gel matrix
http://purl.obolibrary.org/obo/OBI_0001122	diffractometer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A measurement device for analyzing the structure of a material from the scattering pattern produced when a beam of radiation or particles (e.g. X rays or neutrons) interacts with it.
http://purl.obolibrary.org/obo/OBI_0001123	microdissection instrument	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used for the dissection of tissues under magnification.
http://purl.obolibrary.org/obo/OBI_0001124	micropipette puller	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is used to fabricate glass micropipettes.
http://purl.obolibrary.org/obo/OBI_0001125	laser scanning confocal microscope	http://purl.obolibrary.org/obo/OBI_0001079	confocal microscope		A confocal microscope that obtains high-resolution optical images with depth selectivity, in which a laser beam passes through a light source aperture and then is focused by an objective lens into a small (ideally diffraction limited) focal volume within or on the surface of a specimen.
http://purl.obolibrary.org/obo/OBI_0001126	digital microscope	http://purl.obolibrary.org/obo/OBI_0400169	microscope		A microscope that uses optics and a charge-coupled device (CCD) camera to output a digital image to a monitor.
http://purl.obolibrary.org/obo/OBI_0001127	freeze substitution system	http://purl.obolibrary.org/obo/OBI_0000968	device		A device or system for dehydrating and then chemically fixing electron microscopy samples at low temperatures in preparation for various treatments including embedding in resins.
http://purl.obolibrary.org/obo/OBI_0001128	micropipette	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A microinjection device that is used to measure very small volumes of liquids.
http://purl.obolibrary.org/obo/OBI_0001129	voltage clamp device	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A device that is used to measure the ion currents across the membrane of excitable cells, such as neurons, while holding the membrane voltage at a set level.
http://purl.obolibrary.org/obo/OBI_0001130	vacuum oven	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device that heats materials in a vacuum.
http://purl.obolibrary.org/obo/OBI_0001131	slide warmer	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device that is used to heat microscope slides.
http://purl.obolibrary.org/obo/OBI_0001132	capillary electrophoresis instrument	http://purl.obolibrary.org/obo/OBI_0001053	electrophoresis system		An electrophoresis system that is used to separate ionic species by their charge and frictional forces and mass.
http://purl.obolibrary.org/obo/OBI_0001133	denaturing high-performance liquid chromatography instrument	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A high performance liquid chromatography instrument that employs temperature-dependent separation of DNA containing mismatched base pairs from PCR-amplified DNA fragments for chromatographic mutation analysis.
http://purl.obolibrary.org/obo/OBI_0001134	agarose gel electrophoresis system	http://purl.obolibrary.org/obo/OBI_0001121	gel electrophoresis system		A gel electrophoresis system that is used to separate DNA or RNA molecules by size, achieved by moving negatively charged nucleic acid molecules through an agarose matrix with an electric field.
http://purl.obolibrary.org/obo/OBI_0001135	balance	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A measuring instrument that is used to determine the weight or mass of an object.
http://purl.obolibrary.org/obo/OBI_0001136	surface plasmon resonance instrument	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A tool for measuring adsorption of material onto planar metal (typically gold and silver) surfaces or onto the surface of metal nanoparticles.
http://purl.obolibrary.org/obo/OBI_0001137	protein sequencer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		An device that is used to determine the order of amino acids in protein sequences.
http://purl.obolibrary.org/obo/OBI_0001139	liquid chromatography instrument	http://purl.obolibrary.org/obo/OBI_0000048	chromatography device		A chromatography device that dissolves a mixture in liquid mobile phase to separate the analyte to be measured from other molecules in the mixture and allows it to be isolated
http://purl.obolibrary.org/obo/OBI_0001140	spike-in quality control role	http://purl.obolibrary.org/obo/OBI_0000025	reference substance role		a reference substance role that is borne by a material entity with a known amount which is mixed into the evaluant of assays for quality control or data normalization purposes
http://purl.obolibrary.org/obo/OBI_0001141	individual organism identifier	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol		a CRID symbol used to distinguish one individual organism from another.
http://purl.obolibrary.org/obo/OBI_0001142	dye swap quality control role	http://purl.obolibrary.org/obo/OBI_0000025	reference substance role		a reference substance role that is borne by a material entity used in a dye swap design experiment for quality control or data normalization purposes
http://purl.obolibrary.org/obo/OBI_0001144	binding constant	http://purl.obolibrary.org/obo/OBI_0003142	quantitative binding datum		A quantitative binding datum that is expressed as a scalar number and a unit, which can be utilized in equations that model the binding process independent of the specific assay performed.
http://purl.obolibrary.org/obo/OBI_0001145	3D structure determination of bound molecular complex assay	http://purl.obolibrary.org/obo/OBI_0003117	3D molecular structure determination assay		A 3D molecular structure determination assay in which a complex of 2 or more molecular enties is characterized which provides information on their binding configuration.
http://purl.obolibrary.org/obo/OBI_0001146	binding assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay with the objective to characterize the disposition of two or more material entities to form a complex.
http://purl.obolibrary.org/obo/OBI_0001147	cell culture expansion	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a process that results in the increase of cell numbers
http://purl.obolibrary.org/obo/OBI_0001148	gene knock out	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation		a genetic transformation that renders a gene non-functional, e.g. due to a point mutation, or the removal of all, or part of, the gene using recombinant methods.
http://purl.obolibrary.org/obo/OBI_0001149	gene knock in	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation		a genetic transformation that involves the insertion of a protein coding cDNA sequence at a particular locus in an organism's chromosome. Typically, this is done in mice since the technology for this process is more refined, and because mouse embryonic stem cells are easily manipulated. The difference between knock-in technology and transgenic technology is that a knock-in involves a gene inserted into a specific locus, and is a "targeted" insertion.
http://purl.obolibrary.org/obo/OBI_0001150	chromosomal substitution	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation		A genetic transformation in which all, or part, of a chromosome from a donor replaces that of the recipient. It does not include chromosome recombination. For single gene insertion, use the term 'gene knock in'.
http://purl.obolibrary.org/obo/OBI_0001151	genetically modified material	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a material entity, organism or cell,  that is the output of a genetic transformation process.
http://purl.obolibrary.org/obo/OBI_0001152	transfection	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation		a genetic transformation which relies on the use of physical, electrical and chemical phenomena to introduce DNA or RNA into a cell
http://purl.obolibrary.org/obo/OBI_0001153	genetic transformation objective	http://purl.obolibrary.org/obo/OBI_0000456	material transformation objective		a material transformation objective aims to create genetically modified organism or cell
http://purl.obolibrary.org/obo/OBI_0001154	induced mutagenesis	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation		A genetic transformation that is the modification of the genetic material (either coding or non-coding) of an organism caused by mutagenic processes, compounds, or irradiation.
http://purl.obolibrary.org/obo/OBI_0001155	3D structural organization datum	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum that describes the structural orientation of a material entity in 3D space.
http://purl.obolibrary.org/obo/OBI_0001156	age since planting measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since planting, the process of placing a plant in media (e.g. soil) to allow it to grow, which excludes sowing.
http://purl.obolibrary.org/obo/OBI_0001157	age since hatching measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since hatching, the process of emergence from an egg.
http://purl.obolibrary.org/obo/OBI_0001159	age since egg laying measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since egg laying, the process of the production of egg(s) by an organism.
http://purl.obolibrary.org/obo/OBI_0001160	assay validation objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		an objective specification to check the accuracy or the quality of the results of an assay by comparison with independent results
http://purl.obolibrary.org/obo/OBI_0001161	age since germination measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since germination, the process consisting of physiological and developmental changes by a seed, spore, pollen grain (microspore), or zygote that occur after release from dormancy, and encompassing events prior to and including the first visible indications of growth.
http://purl.obolibrary.org/obo/OBI_0001162	validation by reverse transcription PCR design	http://purl.obolibrary.org/obo/OBI_0500000	study design		a study design in which checks the accuracy or the quality of the result of an assay  by comparing with reverse transcription PCR results
http://purl.obolibrary.org/obo/OBI_0001163	age since eclosion measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since eclosion, the process of emergence of an adult insect from its pupa or cocoon.
http://purl.obolibrary.org/obo/OBI_0001164	age since sowing measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since sowing, the process of placing a seed or spore in some media with the intention to invoke germination.
http://purl.obolibrary.org/obo/OBI_0001165	age since coitus measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since coitus, the process of copulation that occurs during the process of sexual reproduction.
http://purl.obolibrary.org/obo/OBI_0001166	validation by real time PCR design	http://purl.obolibrary.org/obo/OBI_0500000	study design		a study design in which the accuracy or the quality of the result of an assay is checked by comparing with real time PCR results
http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum		A time measurement datum that is the result of measurement of age of an organism
http://purl.obolibrary.org/obo/OBI_0001168	age since fertilization measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since fertilization, the process of the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote.
http://purl.obolibrary.org/obo/OBI_0001169	age since birth measurement datum	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum that is the result of the measurement of the age of an organism since birth, the process of emergence and separation of offspring from the mother.
http://purl.obolibrary.org/obo/OBI_0001170	reverse transcription polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay		An assay that determines the concentration of RNA in a sample in which an RNA strand is first reverse transcribed into its DNA complement (complementary DNA, or cDNA) using the enzyme reverse transcriptase, and the resulting cDNA is amplified using traditional or real-time PCR.
http://purl.obolibrary.org/obo/OBI_0001172	dose response curve	http://purl.obolibrary.org/obo/IAO_0000573	line graph		A data item of paired values, one indicating the dose of a material, the other quantitating a measured effect at that dose. The dosing intervals are chosen so that effect values be interpolated by a plotting a curve.
http://purl.obolibrary.org/obo/OBI_0001173	service	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which a service provider performs a task (i.e. a planned process) for a service consumer.
http://purl.obolibrary.org/obo/OBI_0001175	selective organism creation objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		an objective specification to generate a population or type of organism within species that have some uniform behavioral, morphological, physiological, or genetic characteristics with similarly bred organisms.
http://purl.obolibrary.org/obo/OBI_0001176	Individual epitope immunization in vivo	http://purl.obolibrary.org/obo/OBI_1110015	Immunization in vivo		An immunization in which an individual epitope is administered into a host organism.
http://purl.obolibrary.org/obo/OBI_0001177	RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay		An assay that determines the sequence of an RNA molecule.
http://purl.obolibrary.org/obo/OBI_0001180	half maximal effective concentration (EC50)	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		half maximal effective concentration (EC50) is a scalar measurement datum corresponding to the concentration of a compound which induces a response halfway between the baseline and maximum after some specified exposure time.
http://purl.obolibrary.org/obo/OBI_0001181	binding datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that states if two or more material entities have the disposition to form a complex, and if so, how strong that disposition is.
http://purl.obolibrary.org/obo/OBI_0001182	negative binding datum	http://purl.obolibrary.org/obo/OBI_0003141	categorical binding datum		A categorical binding datum that states that there is no significant disposition of two or more entities to form a complex.
http://purl.obolibrary.org/obo/OBI_0001187	infectious agent detection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the presence or amount of an infectious agent in an evaluant
http://purl.obolibrary.org/obo/OBI_0001191	half maximal inhibitory concentration (IC50)	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		Half maximal inhibitory concentration (IC50) is a scalar measurement datum that measures the effectiveness of a compound to competitively inhibit a given process, and corresponds to the concentration of the compound at which it reaches half of its maximum inhibitory effect.
http://purl.obolibrary.org/obo/OBI_0001192	epitope specific immune intervention	http://purl.obolibrary.org/obo/OBI_0001174	passive immunization		An administration in vivo to either actively or passively immunize an organism in order to induce a response against a specific immune epitope
http://purl.obolibrary.org/obo/OBI_0001193	epitope specific cytokine production by T cells	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		A process of cytokine production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001194	ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects transforming growth factor-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001195	operator variation design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that assesses the operator performance and relation to data consistency and quality.
http://purl.obolibrary.org/obo/OBI_0001196	cytometric bead array assay measuring epitope specific IP-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects IP-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001197	comparative genome hybridization by array design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that detects genomic copy number variations using microarray technology.
http://purl.obolibrary.org/obo/OBI_0001198	assay measuring epitope specific interleukin-27 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-27 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001199	in vivo design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that is conducted entirely in a living organism, e.g. a compound treatment in a mouse model.
http://purl.obolibrary.org/obo/OBI_0001200	genotyping by high throughput sequencing design	http://purl.obolibrary.org/obo/OBI_0001444	genotyping design		A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using high througput sequencing techniques.
http://purl.obolibrary.org/obo/OBI_0001201	epitope specific tolerance induction by T cells	http://purl.obolibrary.org/obo/GO_0002507	tolerance induction		A process of tolerance induction by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001202	innate behavior design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which the innate behavior of the organism is examined, e.g. path finding in bees.
http://purl.obolibrary.org/obo/OBI_0001203	detection of specific nucleic acids with complementary probes assay measuring epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001264	assay measuring epitope specific transforming growth factor-beta production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects transforming growth factor-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001204	SNP microarray	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray used to detect polymorphisms in DNA samples
http://purl.obolibrary.org/obo/OBI_0001205	cell component comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that compares samples from different cell components.
http://purl.obolibrary.org/obo/OBI_0001206	ELISPOT assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects granulocyte macrophage colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001207	epitope specific macrophage inflammatory protein-1 alpha production by T cells	http://purl.obolibrary.org/obo/GO_0071608	macrophage inflammatory protein-1 alpha production		A process of macrophage inflammatory protein-1 alpha production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001208	epitope specific T cell activation	http://purl.obolibrary.org/obo/GO_0042110	T cell activation		A process of T cell activation resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001209	assay measuring epitope specific interleukin-10 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001210	cytometric bead array assay measuring epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects transforming growth factor-beta production by T cells
http://purl.obolibrary.org/obo/OBI_0001211	ex vivo design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design where all or part of an organism is removed and studied in vitro, e.g. part of a mouse is removed and cultured in vitro. A cell culture with an established cell line is an in vitro experiment.
http://purl.obolibrary.org/obo/OBI_0001212	epitope specific type IV hypersensitivity by T cells	http://purl.obolibrary.org/obo/GO_0001806	type IV hypersensitivity		A process of type IV hypersensitivity by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001214	normalization testing design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that tests different normalization procedures.
http://purl.obolibrary.org/obo/OBI_0001215	intracellular material detection assay measuring epitope specific perforin release	http://purl.obolibrary.org/obo/OBI_0001497	assay measuring epitope specific perforin release by T cells		A flow cytometry assay that detects epitope specific perforin release by T cells.
http://purl.obolibrary.org/obo/OBI_0001216	cell culture analyte detection bioassay measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_0001445	assay measuring epitope specific interleukin-2 production by T cells		A reporter cell line analyte detection bioassay that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001217	assay measuring epitope specific interleukin-22 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001218	assay measuring epitope specific interleukin-8 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-8 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001219	epitope specific chemokine (C-C motif) ligand 1 production by T cells	http://purl.obolibrary.org/obo/GO_0071610	chemokine (C-C motif) ligand 1 production		A process of chemokine (C-C motif) ligand 1 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001220	cell culture analyte detection bioassay measuring epitope specific interleukin-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0001209	assay measuring epitope specific interleukin-10 production by T cells		A reporter cell line analyte detection bioassay that detects interleukin-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001221	ChIP-chip by SNP array assay	http://purl.obolibrary.org/obo/OBI_0001248	ChIP-chip assay		A ChIP-ChIP assay in which immunoprecipitated chromatin is run on a SNP array to detect polymorphism specific DNA elements in the isolated chromatin
http://purl.obolibrary.org/obo/OBI_0001222	ELISA measuring epitope specific RANTES production by T cells	http://purl.obolibrary.org/obo/OBI_0001232	assay measuring epitope specific RANTES production by T cells		An enzyme-linked immunosorbent assay that detects RANTES production by T cells.
http://purl.obolibrary.org/obo/OBI_0001223	cytometric bead array assay measuring epitope specific interleukin-1 beta production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-1 beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001225	genetic population background information	http://purl.obolibrary.org/obo/OBI_0001404	genetic characteristics information		a genetic characteristics information which is a part of genotype information that identifies the population of organisms
http://purl.obolibrary.org/obo/OBI_0001226	environmental history design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which some aspect of the organism's environmental history is studied, such as exposure to teratogen, radiation, climate etc.
http://purl.obolibrary.org/obo/OBI_0001227	ELISPOT assay measuring epitope specific interleukin-6 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-6 production by T cells
http://purl.obolibrary.org/obo/OBI_0001228	in vivo assay measuring epitope specific helper T cell enhancement of a B cell mediated immune response	http://purl.obolibrary.org/obo/OBI_0001495	in vivo assay measuring epitope specific T cell helper activity		A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance an antibody response.
http://purl.obolibrary.org/obo/OBI_0001229	plasmon resonance assay measuring the dissociation constant [KD] of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0002097	assay measuring the dissociation constant [KD] of a T cell epitope:MHC:TCR complex		A surface plasmon resonance binding assay that measures the dissociation constant [KD] of an epitope:MHC complex binding with a T cell receptor.
http://purl.obolibrary.org/obo/OBI_0001230	assay measuring epitope specific interleukin-5 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-5 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001231	ELISA measuring epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001264	assay measuring epitope specific transforming growth factor-beta production by T cells		An enzyme-linked immunosorbent assay that detects transforming growth factor-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001232	assay measuring epitope specific RANTES production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects RANTES production by T cells.
http://purl.obolibrary.org/obo/OBI_0001233	assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects granulocyte macrophage colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001234	epigenetic modification identification objective	http://purl.obolibrary.org/obo/OBI_0000131	molecular feature identification objective		A molecular feature identification objective that aims to detect epigenetic modifications, such as DNA methylation, histone modifications.
http://purl.obolibrary.org/obo/OBI_0001235	transcription profiling by tiling array assay	http://purl.obolibrary.org/obo/OBI_0001463	transcription profiling by array assay		A transcription profiling by array assay that uses a tiling path array.
http://purl.obolibrary.org/obo/OBI_0001236	ELISA measuring epitope specific interleukin-22 production by T cells	http://purl.obolibrary.org/obo/OBI_0001217	assay measuring epitope specific interleukin-22 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001237	assay measuring epitope specific interleukin-21 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001238	ELISA measuring epitope specific interleukin-9 production by T cells	http://purl.obolibrary.org/obo/OBI_0001253	assay measuring interleukin-9 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001239	transcription profiling by high throughput sequencing design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which sequencing technology (e.g. Solexa/454) is used to generate RNA sequence, analyse the transcibed regions of the genome, and/or to quantitate transcript abundance
http://purl.obolibrary.org/obo/OBI_0001240	intracellular cytokine staining assay measuring epitope specific interleukin-6 production by T cells	http://purl.obolibrary.org/obo/OBI_0001451	assay measuring epitope specific interleukin-6 production by T cells		A flow cytometry assay that detects interleukin-6 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001241	cell culture analyte detection bioassay measuring epitope specific interleukin-4 production by T cells	http://purl.obolibrary.org/obo/OBI_0001450	assay measuring epitope specific interleukin-4 production by T cells		A reporter cell line analyte detection bioassay that detects interleukin-4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001242	detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001788	detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects tumor necrosis factor alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001243	cytometric bead array assay measuring epitope specific monocyte chemotactic protein-1 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects monocyte chemotactic protein-1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001244	ELISA measuring epitope specific interleukin-23 production by T cells	http://purl.obolibrary.org/obo/OBI_0001363	assay measuring epitope specific interleukin-23 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-23 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001245	detection of specific nucleic acids with complementary probes assay measuring epitope specific perforin release	http://purl.obolibrary.org/obo/OBI_0001497	assay measuring epitope specific perforin release by T cells		A detection of specific nucleic acids with complementary probes assay that detects epitope specific perforin release by T cells.
http://purl.obolibrary.org/obo/OBI_0001246	ELISA measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		An enzyme-linked immunosorbent assay that detects tumor necrosis factor superfamily cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_0001247	genotyping by high throughput sequencing assay	http://purl.obolibrary.org/obo/OBI_0000435	genotyping assay		A genotyping assay that uses a high througput sequencer
http://purl.obolibrary.org/obo/OBI_0001249	epitope specific T cell tolerance induction	http://purl.obolibrary.org/obo/GO_0002517	T cell tolerance induction		A process of T cell tolerance induction resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001250	obsolete intracellular material detection by flow cytometry assay  of epitope specific cytotoxic T cell degranulation	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An intracellular material detection by flow cytometry assay  that measures epitope specific cytotoxic T cell degranulation
http://purl.obolibrary.org/obo/OBI_0001251	assay measuring epitope specific interleukin-13 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-13 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001252	array platform variation design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which the array platform is compared, e.g. Agilent versus Affymetrix.
http://purl.obolibrary.org/obo/OBI_0001253	assay measuring interleukin-9 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001254	epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/GO_0032632	interleukin-3 production		A process of interleukin-3 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001255	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-5 production by T cells	http://purl.obolibrary.org/obo/OBI_0001230	assay measuring epitope specific interleukin-5 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-5 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001256	epitope specific lymphotoxin A production by T cells	http://purl.obolibrary.org/obo/GO_0032641	lymphotoxin A production		A process of lymphotoxin A production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001257	epitope specific interleukin-1 alpha production by T cells	http://purl.obolibrary.org/obo/GO_0032610	interleukin-1 alpha production		A process of interleukin-1 alpha production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001258	ChIP-seq design	http://purl.obolibrary.org/obo/OBI_0001425	protein binding site identification design		A study design which aims to identify protein and DNA interactions using a combination of chromatin immunoprecipitation and high throughput sequencing. Massively parallel sequence analyses are used in conjunction with whole-genome sequence databases to analyze the interaction pattern of any protein with DNA, or the pattern of any epigenetic chromatin modifications.
http://purl.obolibrary.org/obo/OBI_0001259	translational bias design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that characterizes the association of transcripts and translation machinery.
http://purl.obolibrary.org/obo/OBI_0001260	ELISA measuring epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/OBI_0001406	assay measuring epitope specific interleukin-3 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-3 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001261	ELISA measuring epitope specific interleukin-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001388	assay measuring epitope specific interleukin-1 alpha production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001262	epitope specific interleukin-27 production by T cells	http://purl.obolibrary.org/obo/GO_0032631	interleukin-27 production		A process of interleukin-27 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001263	in vivo assay measuring epitope specific helper T cell enhancement of a T cell mediated immune response	http://purl.obolibrary.org/obo/OBI_0001495	in vivo assay measuring epitope specific T cell helper activity		A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance a T cell response.
http://purl.obolibrary.org/obo/OBI_0001264	assay measuring epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects transforming growth factor-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001265	FWER adjusted p-value	http://purl.obolibrary.org/obo/OBI_0000071	quantitative confidence value		A quantitative confidence value resulting from a multiple testing error correction method which adjusts the p-value used as input to control for Type I error in the context of multiple pairwise tests
http://purl.obolibrary.org/obo/OBI_0001266	DNA methylation profiling by high throughput sequencing assay	http://purl.obolibrary.org/obo/OBI_0000634	DNA methylation profiling assay		A DNA methylation profiling assay in which the methylation state of DNA is determined and can be compared between samples using sequencing based technology
http://purl.obolibrary.org/obo/OBI_0001267	epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/GO_0071604	transforming growth factor beta production		A process of transforming growth factor-beta production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001268	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-12 production by T cells	http://purl.obolibrary.org/obo/OBI_0001391	assay measuring epitope specific interleukin-12 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-12 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001269	assay measuring epitope specific cytotoxic T cell degranulation	http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding		A T cell epitope dependent biological activity assay that detects cytotoxic T cell degranulation.
http://purl.obolibrary.org/obo/OBI_0001270	cell culture analyte detection bioassay measuring epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001264	assay measuring epitope specific transforming growth factor-beta production by T cells		A reporter cell line analyte detection bioassay that detects transforming growth factor-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001272	ELISPOT assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects tumor necrosis factor superfamily cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_0001273	cell culture analyte detection bioassay measuring epitope specific interleukin-5 production by T cells	http://purl.obolibrary.org/obo/OBI_0001230	assay measuring epitope specific interleukin-5 production by T cells		A reporter cell line analyte detection bioassay that detects interleukin-5 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001274	genotyping by array assay	http://purl.obolibrary.org/obo/OBI_0001985	microarray assay		A genotyping assay that uses an array
http://purl.obolibrary.org/obo/OBI_0001275	epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/GO_0032619	interleukin-16 production		A process of interleukin-16 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001276	assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects production of chemokine (C-C motif) ligand 1 by T cells.
http://purl.obolibrary.org/obo/OBI_0001277	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_0001445	assay measuring epitope specific interleukin-2 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001278	DNA methylation profiling by array design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which the methylation state of DNA is determined and is compared between samples using array technology.
http://purl.obolibrary.org/obo/OBI_0001279	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-22 production by T cells	http://purl.obolibrary.org/obo/OBI_0001217	assay measuring epitope specific interleukin-22 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001280	assay measuring epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001281	ELISA measuring epitope specific IP-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0001308	assay measuring epitope specific IP-10 production by T cells		An enzyme-linked immunosorbent assay that detects IP-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001282	translation profiling assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An assay in which surface-bound, translationally competent ribosome complexes are used to generate a translation profile for mRNA, which mRNA may be a single molecular species, or a combination of species, including complex mixtures such as those found in the set of mRNAs isolated from a cell or tissue. One or more components of the surface-bound ribosome complex may be labeled at specific positions to permit analysis of multiple or single molecules for determination of ribosomal conformational changes and translation kinetics. Translation profiles are used as the basis for comparison of an mRNA or set of mRNA species. The translation profile can be used to determine such characteristics as kinetics of initiation, kinetic of elongation, identity of the polypeptide product, and the like. Analysis of translation profiles may be used to determine differential gene expression, optimization of mRNA sequences for expression, screening drug candidates for an effect on translation.
http://purl.obolibrary.org/obo/OBI_0001283	ELISA measuring epitope specific interleukin-15 production by T cells	http://purl.obolibrary.org/obo/OBI_0001292	assay measuring epitope specific interleukin-15 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-15 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001284	cytometric bead array assay measuring epitope specific interleukin-12 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-12 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001285	in vitro design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that is done in a test tube or a culture dish, e.g. A bacterial invasion assay in an established cell culture.
http://purl.obolibrary.org/obo/OBI_0001286	RNAi profiling by array design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which experiment double stranded RNA is synthesized with a sequence complementary to a gene(s) of interest and introduced into a cell or organism, where it is recognized as exogenous genetic material and activates the RNAi pathway resulting in knockdown of the transcripts and providing a means to study downstream changes in gene expression.
http://purl.obolibrary.org/obo/OBI_0001288	ELISA measuring epitope specific lymphotoxin A production by T cells	http://purl.obolibrary.org/obo/OBI_0001327	assay measuring epitope specific lymphotoxin A production by T cells		An enzyme-linked immunosorbent assay that detects lymphotoxin A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001289	cytometric bead array assay measuring epitope specific interleukin-5 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-5 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001290	transcription profiling by array design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that identifies forms and abundance of transcripts in the genome using microarray technology.
http://purl.obolibrary.org/obo/OBI_0001291	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17 production by T cells	http://purl.obolibrary.org/obo/OBI_0001295	assay measuring epitope specific interleukin-17 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-17 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001292	assay measuring epitope specific interleukin-15 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-15 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001293	disease state design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which the pathological condition of a part, organ, or system of an organism is studied. The etiology may be from infection, genetic defect, or environmental stress.
http://purl.obolibrary.org/obo/OBI_0001294	wild type organism genotype information	http://purl.obolibrary.org/obo/OBI_0001305	genotype information		a genotype information about an organism and includes information that there are no known modifications to the genetic background. Generally it is the genotype information of a representative individual from a class of organisms.
http://purl.obolibrary.org/obo/OBI_0001295	assay measuring epitope specific interleukin-17 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-17 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001296	cytometric bead array assay measuring epitope specific interleukin-17 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-17 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001297	cytometric bead array assay measuring epitope specific interleukin-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001298	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-21 production by T cells	http://purl.obolibrary.org/obo/OBI_0001237	assay measuring epitope specific interleukin-21 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001299	intracellular cytokine staining assay measuring epitope specific interleukin-5 production by T cells	http://purl.obolibrary.org/obo/OBI_0001230	assay measuring epitope specific interleukin-5 production by T cells		A flow cytometry assay that detects interleukin-5 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001300	cytometric bead array assay measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001301	cell culture analyte detection bioassay measuring epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/OBI_0001280	assay measuring epitope specific interleukin-16 production by T cells		A reporter cell line analyte detection bioassay that detects interleukin-16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001302	ELISA measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001333	assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells		An enzyme-linked immunosorbent assay that detects macrophage inflammatory protein-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001303	intracellular cytokine staining assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001233	assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells		A flow cytometry assay that detects granulocyte macrophage colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001304	RNAi profiling by array assay	http://purl.obolibrary.org/obo/OBI_0001985	microarray assay		An assay in which double stranded RNA is synthesized with a sequence complementary to a gene(s) of interest and introduced into a cell or organism, where it is recognized as exogenous genetic material and activates the RNAi pathway resulting in knockdown of the transcripts and providing a means to study downstream changes in gene expression.
http://purl.obolibrary.org/obo/OBI_0001305	genotype information	http://purl.obolibrary.org/obo/OBI_0001404	genetic characteristics information		a genetic characteristics information that is about the genetic material of an organism and minimally includes information about the genetic background and can in addition contain information about specific alleles, genetic modifications, etc.
http://purl.obolibrary.org/obo/OBI_0001306	RNA stability design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that examines the stability and/or decay of RNA transcripts.
http://purl.obolibrary.org/obo/OBI_0001308	assay measuring epitope specific IP-10 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects IP-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001309	intracellular cytokine staining assay measuring epitope specific interleukin-13 production by T cells	http://purl.obolibrary.org/obo/OBI_0001251	assay measuring epitope specific interleukin-13 production by T cells		A flow cytometry assay that detects interleukin-13 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001310	species comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that assays differences between distinct species.
http://purl.obolibrary.org/obo/OBI_0001311	X-ray crystallography assay determining the 3D structure of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0001999	3D molecular structure determination assay of a T cell epitope:MHC:TCR complex		A X-ray crystallography 3D molecular structure determination assay that characterizes the 3-dimensional molecular structure of a T cell epitope:MHC:TCR complex.
http://purl.obolibrary.org/obo/OBI_0001313	transcription profiling by RT-PCR design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design which aims to examine the transcriptome of a biological sample by reverse transcription PCR (RT-PCR).
http://purl.obolibrary.org/obo/OBI_0001314	epitope specific T cell enhancement of B cell mediated immune response	http://purl.obolibrary.org/obo/GO_0035399	helper T cell enhancement of B cell mediated immune response		A process of T cell enhancement of B cell mediated immune response resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001315	ELISA measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells	http://purl.obolibrary.org/obo/OBI_0001276	assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells		An enzyme-linked immunosorbent assay that detects chemokine (C-C motif) ligand 1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001316	epitope specific interleukin-21 production by T cells	http://purl.obolibrary.org/obo/GO_0032625	interleukin-21 production		A process of interleukin-21 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001317	flow cytometry assay measuring cell-cell binding of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_1110124	assay measuring qualitative binding of a T cell epitope:MHC:TCR complex		A flow cytometry assay that measures the cell-cell binding of an epitope:MHC complex binding with a T cell receptor.
http://purl.obolibrary.org/obo/OBI_0001318	proteomic profiling by array assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An assay that detects proteins in a sample (quantified or otherwise analyzed), e.g. antibody profiling using an array based technology.
http://purl.obolibrary.org/obo/OBI_0001319	cell culture analyte detection bioassay measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001414	assay measuring epitope specific interferon-gamma production by T cells		A reporter cell line analyte detection bioassay that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001322	ELISPOT assay measuring epitope specific granzyme B release by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects  epitope specific granzyme B release by T cells.
http://purl.obolibrary.org/obo/OBI_0001323	microRNA profiling by array design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which a microRNA array is used to analyse the microRNA component of the transcriptome.
http://purl.obolibrary.org/obo/OBI_0001324	in vivo assay measuring T cell epitope specific tolerance induction	http://purl.obolibrary.org/obo/OBI_0001488	epitope tolerance induction experiment		An efficacy of T cell epitope intervention experiment that uses a tolerance induction intervention experiment.
http://purl.obolibrary.org/obo/OBI_0001325	detection of specific nucleic acids with complementary probes assay measuring epitope specific RANTES production by T cells	http://purl.obolibrary.org/obo/OBI_0001232	assay measuring epitope specific RANTES production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects RANTES production by T cells.
http://purl.obolibrary.org/obo/OBI_0001326	cytometric bead array assay measuring epitope specific interleukin-4 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-4 production by T cells
http://purl.obolibrary.org/obo/OBI_0001327	assay measuring epitope specific lymphotoxin A production by T cells	http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A T cell epitope specific cytokine production assay that detects lymphotoxin A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001328	organism development design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that assays events associated with development. Development applies to organism(s) acquiring a mature state.
http://purl.obolibrary.org/obo/OBI_0001329	family history design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which the family history such as traits, characteristics, susceptibility to disease is studied.
http://purl.obolibrary.org/obo/OBI_0001330	ELISA measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells	http://purl.obolibrary.org/obo/OBI_0001459	assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells		An enzyme-linked immunosorbent assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001331	transcription profiling identification objective	http://purl.obolibrary.org/obo/OBI_0000131	molecular feature identification objective		A molecular feature identification objective that aims to characterize the abundance of transcripts
http://purl.obolibrary.org/obo/OBI_0001332	DNA methylation profiling by array assay	http://purl.obolibrary.org/obo/OBI_0000634	DNA methylation profiling assay		A DNA methylation profiling assay in which the methylation state of DNA is determined and can be compared between samples using array technology
http://purl.obolibrary.org/obo/OBI_0001333	assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects macrophage inflammatory protein-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001334	epitope specific granulocyte colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/GO_0071611	granulocyte colony-stimulating factor production		A process of granulocyte colony stimulating factor production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001335	microRNA profiling by array assay	http://purl.obolibrary.org/obo/OBI_0001926	microRNA profiling assay		An assay that analyses the microRNA component of the transcriptome using a microRNA array.
http://purl.obolibrary.org/obo/OBI_0001336	quality control testing design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which some aspects of the experiment is quality controlled for the purposes of quality assurance.
http://purl.obolibrary.org/obo/OBI_0001337	clinical history design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that the organism's clinical history of diagnosis, treatments, e.g. vaccinations, surgery etc. is studied.
http://purl.obolibrary.org/obo/OBI_0001339	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-4 production by T cells	http://purl.obolibrary.org/obo/OBI_0001450	assay measuring epitope specific interleukin-4 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001341	cell culture analyte detection bioassay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001233	assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells		A reporter cell line analyte detection bioassay that detects granulocyte macrophage colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001342	intracellular cytokine staining assay measuring epitope specific interleukin-21 production by T cells	http://purl.obolibrary.org/obo/OBI_0001237	assay measuring epitope specific interleukin-21 production by T cells		A flow cytometry assay that detects interleukin-21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001343	detection of specific nucleic acids with complementary probes assay measuring epitope specific monocyte chemotactic protein-1 production by T cells	http://purl.obolibrary.org/obo/OBI_0001465	assay measuring epitope specific monocyte chemotactic protein-1 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects monocyte chemotactic protein-1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001344	ELISA measuring epitope specific monocyte chemotactic protein-1 production by T cells	http://purl.obolibrary.org/obo/OBI_0001465	assay measuring epitope specific monocyte chemotactic protein-1 production by T cells		An enzyme-linked immunosorbent assay that detects monocyte chemotactic protein-1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001345	assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001346	ELISA measuring epitope specific interleukin-21 production by T cells	http://purl.obolibrary.org/obo/OBI_0001237	assay measuring epitope specific interleukin-21 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001348	in vivo skin test assay measuring T cell epitope specific type IV hypersensitivity	http://purl.obolibrary.org/obo/OBI_0001484	assay measuring T cell epitope specific in vivo activity		An efficacy of T cell epitope intervention experiment that detects epitope specific type IV hypersensitivity.
http://purl.obolibrary.org/obo/OBI_0001349	cytometric bead array assay measuring epitope specific interleukin-13 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-13 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001350	detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001414	assay measuring epitope specific interferon-gamma production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001351	epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/GO_0071706	tumor necrosis factor superfamily cytokine production		A process of tumor necrosis factor superfamily cytokine production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001352	allele information	http://purl.obolibrary.org/obo/OBI_0001364	genetic alteration information		a genetic alteration information that about one of two or more alternative forms of a gene or marker sequence and differing from other alleles at one or more mutational sites based on sequence. Polymorphisms are included in this definition.
http://purl.obolibrary.org/obo/OBI_0001353	cytometric bead array assay measuring epitope specific tumor necrosis factor alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001416	assay measuring epitope specific tumor necrosis factor alpha production by T cells		A cytometric bead array assay that detects tumor necrosis factor alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001354	ELISPOT assay measuring epitope specific interleukin-17 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-17 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001356	detection of specific nucleic acids with complementary probes assay measuring epitope specific interferon-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001390	assay measuring epitope specific interferon-beta production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interferon-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001357	detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001233	assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects granulocyte macrophage colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001358	post-transcriptional modification design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		A study design in which a modification of the transcriptome, proteome (not genome) is made, for example RNAi, antibody targeting.
http://purl.obolibrary.org/obo/OBI_0001359	ELISA measuring epitope specific interleukin-8 production by T cells	http://purl.obolibrary.org/obo/OBI_0001218	assay measuring epitope specific interleukin-8 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-8 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001360	cytometric bead array assay measuring epitope specific interleukin-6 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-6 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001361	transcription profiling by RT-PCR assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay		A transcription profiling assay that uses reverse transcription PCR (RT-PCR).
http://purl.obolibrary.org/obo/OBI_0001362	epitope specific chemokine (C-C motif) ligand 4 production by T cells	http://purl.obolibrary.org/obo/GO_0071606	chemokine (C-C motif) ligand 4 production		A process of chemokine (C-C motif) ligand 4 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001363	assay measuring epitope specific interleukin-23 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-23 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001364	genetic alteration information	http://purl.obolibrary.org/obo/OBI_0001404	genetic characteristics information		a genetic characteristics information that is about known changes or the lack thereof from the genetic background, including allele information, duplication, insertion, deletion, etc.
http://purl.obolibrary.org/obo/OBI_0001365	cellular process design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that aims to study the processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
http://purl.obolibrary.org/obo/OBI_0001366	epitope specific RANTES production by T cells	http://purl.obolibrary.org/obo/GO_0071609	chemokine (C-C motif) ligand 5 production		A process of RANTES production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001367	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0001209	assay measuring epitope specific interleukin-10 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001368	cytometric bead array assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects tumor necrosis factor superfamily cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_0001369	wild type allele information	http://purl.obolibrary.org/obo/OBI_0001352	allele information		an allele information that is about the allele found most frequently in natural populations, or in standard laboratory stocks for a given organism.
http://purl.obolibrary.org/obo/OBI_0001370	intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells	http://purl.obolibrary.org/obo/OBI_0001345	assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells		A flow cytometry assay that detects chemokine (C-C motif) ligand 4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001371	epitope specific granzyme B production by T cells	http://purl.obolibrary.org/obo/GO_0071613	granzyme B production		A process of granzyme B production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001373	epitope specific interleukin-8 production by T cells	http://purl.obolibrary.org/obo/GO_0032637	interleukin-8 production		A process of interleukin-8 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001374	injury design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which the response of an organism(s) to injury or damage is studied.
http://purl.obolibrary.org/obo/OBI_0001376	intracellular cytokine staining assay measuring epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/OBI_0001406	assay measuring epitope specific interleukin-3 production by T cells		A flow cytometry assay that detects interleukin-3 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001377	organism status comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that compares samples from live and dead organisms.
http://purl.obolibrary.org/obo/OBI_0001378	ELISA measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells	http://purl.obolibrary.org/obo/OBI_0001345	assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells		An enzyme-linked immunosorbent assay that detects chemokine (C-C motif) ligand 4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001379	cytometric bead array assay measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001380	assay measuring epitope specific interleukin-18 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-18 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001381	epitope specific interleukin-23 production by T cells	http://purl.obolibrary.org/obo/GO_0032627	interleukin-23 production		A process of interleukin-23 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001382	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-27 production by T cells	http://purl.obolibrary.org/obo/OBI_0001198	assay measuring epitope specific interleukin-27 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-27 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001383	detection of specific nucleic acids with complementary probes assay measuring epitope specific IP-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0001308	assay measuring epitope specific IP-10 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects IP-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001384	cell culture analyte detection bioassay measuring epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/OBI_0001406	assay measuring epitope specific interleukin-3 production by T cells		A reporter cell line analyte detection bioassay that detects interleukin-3 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001385	intracellular cytokine staining assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A flow cytometry assay that detects tumor necrosis factor superfamily cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_0001386	epitope specific monocyte chemotactic protein-1 production by T cells	http://purl.obolibrary.org/obo/GO_0071605	monocyte chemotactic protein-1 production		A process of monocyte chemotactic protein-1 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001387	genotyping by array design	http://purl.obolibrary.org/obo/OBI_0001444	genotyping design		A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using microarray technology.
http://purl.obolibrary.org/obo/OBI_0001388	assay measuring epitope specific interleukin-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001389	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-6 production by T cells	http://purl.obolibrary.org/obo/OBI_0001451	assay measuring epitope specific interleukin-6 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-6 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001390	assay measuring epitope specific interferon-beta production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interferon-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001391	assay measuring epitope specific interleukin-12 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-12 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001392	in vivo assay measuring epitope specific T cell killing	http://purl.obolibrary.org/obo/OBI_1110130	assay measuring epitope specific T cell killing		An in vivo cell killing assay that measures the killing of antigen presenting cells (APC) by T cells whose TCR recognizes an epitope presented by the APC.
http://purl.obolibrary.org/obo/OBI_0001394	epitope specific cytotoxic T cell degranulation	http://purl.obolibrary.org/obo/GO_0043316	cytotoxic T cell degranulation		A process of cytotoxic T cell degranulation resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001395	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-23 production by T cells	http://purl.obolibrary.org/obo/OBI_0001363	assay measuring epitope specific interleukin-23 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-23 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001396	stimulus or stress design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		A study design in which the response of an organism(s) to the stress or stimulus is studied, e.g. osmotic stress, heat shock, radiation exposure, behavioral treatment etc.
http://purl.obolibrary.org/obo/OBI_0001397	cytometric bead array assay measuring epitope specific granulocyte colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects granulocyte colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001398	protein and DNA interaction identification objective	http://purl.obolibrary.org/obo/OBI_0000113	sequence feature identification objective		A sequence feature identification objective that aims to characterize the interactions between protein and DNA which includes identification of transcription factor binding sites.
http://purl.obolibrary.org/obo/OBI_0001399	epitope specific interleukin-22 production by T cells	http://purl.obolibrary.org/obo/GO_0032626	interleukin-22 production		A process of interleukin-22 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects tumor necrosis factor superfamily cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_0001401	protocol optimization design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design where different protocols or protocol parameters are compared aims to find an optimized protocol
http://purl.obolibrary.org/obo/OBI_0001402	promoter activity detection by reporter gene assay measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_0001445	assay measuring epitope specific interleukin-2 production by T cells		A promoter activity detection by reporter gene assay that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001404	genetic characteristics information	http://purl.obolibrary.org/obo/IAO_0000027	data item		a data item that is about genetic material including polymorphisms, disease alleles, and haplotypes.
http://purl.obolibrary.org/obo/OBI_0001405	cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects macrophage inflammatory protein-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001406	assay measuring epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-3 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001407	assay measuring epitope specific T cell activation	http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding		A T cell epitope dependent biological activity assay that detects T cell activation.
http://purl.obolibrary.org/obo/OBI_0001408	imprinting design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design where differences in genetic imprinting of maternally- and paternally-inherited chromosomes (e.g., due to in vivo differences in chemical modification and/or chromatin structure) are compared.
http://purl.obolibrary.org/obo/OBI_0001409	cell cycle design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that assays events that occur in relation to the cell cycle, which is the period between the formation of a cell, by division of its mother cell and the time when the cell itself divides to form two daughter cells.
http://purl.obolibrary.org/obo/OBI_0001410	translation profiling design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which surface-bound, translationally competent ribosome complexes are used to generate a translation profile for mRNA, where mRNA may be a single molecular species, or a combination of species, including complex mixtures such as those found in the set of mRNAs isolated from a cell or tissue. One or more components of the surface-bound ribosome complex may be labeled at specific positions to permit analysis of multiple or single molecules for determination of ribosomal conformational changes and translation kinetics. Translation profiles are used as the basis for comparison of an mRNA or set of mRNA species. The translation profile can be used to determine such characteristics as kinetics of initiation, kinetic of elongation, identity of the polypeptide product, and the like. Analysis of translation profiles may be used to determine differential gene expression, optimization of mRNA sequences for expression, screening drug candidates for an effect on translation.
http://purl.obolibrary.org/obo/OBI_0001411	cell type comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that compares cells of different type, for example different cell lines.
http://purl.obolibrary.org/obo/OBI_0001412	cytometric bead array assay measuring epitope specific RANTES production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects RANTES production by T cells.
http://purl.obolibrary.org/obo/OBI_0001413	cell culture analyte detection bioassay measuring epitope specific interleukin-6 production by T cells	http://purl.obolibrary.org/obo/OBI_0001451	assay measuring epitope specific interleukin-6 production by T cells		A reporter cell line analyte detection bioassay that detects interleukin-6 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001414	assay measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001415	epitope specific interleukin-9 production by T cells	http://purl.obolibrary.org/obo/GO_0032638	interleukin-9 production		A process of interleukin-9 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001416	assay measuring epitope specific tumor necrosis factor alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		An assay of epitope specific tumor necrosis factor alpha production by T cells that detects tumor necrosis factor production.
http://purl.obolibrary.org/obo/OBI_0001417	ChIP-chip by tiling array design	http://purl.obolibrary.org/obo/OBI_0001403	ChIP-chip design		A study design which aims to identify protein binding sites in genomic DNA by a combination of chromatin immunoprecipitation and tiling microarray (chip) assays.
http://purl.obolibrary.org/obo/OBI_0001418	dose response design	http://purl.obolibrary.org/obo/OBI_0000951	compound treatment design		A study design that examines the relationship between the size of the administered dose and the extent of the response.
http://purl.obolibrary.org/obo/OBI_0001419	ChIP-chip by tiling array assay	http://purl.obolibrary.org/obo/OBI_0001248	ChIP-chip assay		A ChIP-ChIP assay in which immunoprecipitated chromatin is run on a tiling array that covers stretches of DNA to to detect which elements in those stretches are present in the isolated chromatin
http://purl.obolibrary.org/obo/OBI_0001420	epitope specific helper T cell enhancement of T cell mediated immune response	http://purl.obolibrary.org/obo/GO_0035398	helper T cell enhancement of T cell mediated immune response		A process of helper T cell enhancement of T cell mediated immune response resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001421	epitope specific interferon-beta production by T cells	http://purl.obolibrary.org/obo/GO_0032608	interferon-beta production		A process of interferon-beta production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001422	organism part comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that compares tissues, regions, organs within or between organisms
http://purl.obolibrary.org/obo/OBI_0001423	intracellular material detection measuring epitope specific granzyme B release by T cells	http://purl.obolibrary.org/obo/OBI_0001436	assay measuring epitope specific granzyme B release by T cells		A flow cytometry assay that detects epitope specific granzyme B release by T cells
http://purl.obolibrary.org/obo/OBI_0001425	protein binding site identification design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that investigates protein binding sites on nucleic acids.
http://purl.obolibrary.org/obo/OBI_0001426	sex comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that assays differences associated with an organism's sex, gender or mating type.
http://purl.obolibrary.org/obo/OBI_0001427	transcription profiling by tiling array design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which gene expression on a genome-wide basis is evaluated, without bias toward coding or noncoding regions, using tiling arrays containing oligonucleotides that are either overlapping or spaced at regular intervals.
http://purl.obolibrary.org/obo/OBI_0001429	cell differentiation design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that assays events associated with cell development or differentiation.
http://purl.obolibrary.org/obo/OBI_0001430	transcription profiling design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that identifies forms and abundance of transcripts in the genome.
http://purl.obolibrary.org/obo/OBI_0001432	operon identification design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that identifies locations and members of operons in a genome.
http://purl.obolibrary.org/obo/OBI_0001433	radio immuno assay measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001414	assay measuring epitope specific interferon-gamma production by T cells		A radio immuno assay that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001435	DNA methylation profiling by high throughput sequencing design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which the methylation state of DNA is determined and is compared between samples using high throughput sequencing technology.
http://purl.obolibrary.org/obo/OBI_0001436	assay measuring epitope specific granzyme B release by T cells	http://purl.obolibrary.org/obo/OBI_0001269	assay measuring epitope specific cytotoxic T cell degranulation		A T cell epitope specific cytotoxic T cell degranulation assay that detects granzyme B release by T cells.
http://purl.obolibrary.org/obo/OBI_0001437	intracellular cytokine staining assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells	http://purl.obolibrary.org/obo/OBI_0001459	assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells		A flow cytometry assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001438	ELISA measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001456	assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells		An enzyme-linked immunosorbent assay that detects macrophage inflammatory protein-1 gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001439	epitope specific chemokine (C-X-C motif) ligand 9 production by T cells	http://purl.obolibrary.org/obo/GO_0035393	chemokine (C-X-C motif) ligand 9 production		A process of chemokine (C-X-C motif) ligand 9 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001440	all pairs design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which all specimens are compared to every other specimen.
http://purl.obolibrary.org/obo/OBI_0001441	proteomic profiling by array design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which proteins in a sample are detected, quantified or otherwise analysed, through an array-based technology.
http://purl.obolibrary.org/obo/OBI_0001444	genotyping design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs.
http://purl.obolibrary.org/obo/OBI_0001445	assay measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001446	epitope specific interleukin-15 production by T cells	http://purl.obolibrary.org/obo/GO_0032618	interleukin-15 production		A process of interleukin-15 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001447	epitope specific macrophage inflammatory protein-1 gamma production by T cells	http://purl.obolibrary.org/obo/GO_0071607	macrophage inflammatory protein-1 gamma production		A process of macrophage inflammatory protein-1 gamma production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001448	individual genetic characteristics comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design where genotype, haplotype, or other individual genetic characteristics are compared.
http://purl.obolibrary.org/obo/OBI_0001449	assay measuring epitope specific interleukin-1 beta production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-1 beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001450	assay measuring epitope specific interleukin-4 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001451	assay measuring epitope specific interleukin-6 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-6 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001452	cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0003488	cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A reporter cell line analyte detection bioassay that detects tumor necrosis factor alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001453	intracellular cytokine staining assay measuring epitope specific lymphotoxin A production by T cells	http://purl.obolibrary.org/obo/OBI_0001385	intracellular cytokine staining assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A flow cytometry assay that detects lymphotoxin A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001454	pathogenicity design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which an infective agent such as a bacterium, virus, protozoan, fungus etc. infects a host organism(s) and the infective agent is assayed.
http://purl.obolibrary.org/obo/OBI_0001455	ELISPOT assay measuring epitope specific interleukin-5 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-5 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001456	assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects macrophage inflammatory protein-1 gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001457	cytometric bead array assay measuring epitope specific interleukin-8 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-8 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001459	assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001460	genetic modification design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		A study design in which an organism(s) is studied that has had genetic material removed, rearranged, mutagenized or added, such as in a knock out.
http://purl.obolibrary.org/obo/OBI_0001461	ELISA measuring epitope specific granzyme B release by T cells	http://purl.obolibrary.org/obo/OBI_0001436	assay measuring epitope specific granzyme B release by T cells		An enzyme-linked immunosorbent assay that detects epitope specific granzyme B release by T cells.
http://purl.obolibrary.org/obo/OBI_0001462	epitope specific IP-10 production by T cells	http://purl.obolibrary.org/obo/GO_0071612	IP-10 production		A process of IP-10 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001464	strain comparison design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that assays differences between multiple strains, cultivars, serovars, isolates, lines from organisms of a single species.
http://purl.obolibrary.org/obo/OBI_0001465	assay measuring epitope specific monocyte chemotactic protein-1 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects monocyte chemotactic protein-1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001466	intracellular cytokine staining assay measuring epitope specific interleukin-12 production by T cells	http://purl.obolibrary.org/obo/OBI_0001391	assay measuring epitope specific interleukin-12 production by T cells		A flow cytometry assay that detects interleukin-12 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001467	in vivo assay measuring T cell epitope specific disease exacerbation	http://purl.obolibrary.org/obo/OBI_0001484	assay measuring T cell epitope specific in vivo activity		An efficacy of T cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment.
http://purl.obolibrary.org/obo/OBI_0001468	cell specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture.
http://purl.obolibrary.org/obo/OBI_0001469	monospecific T cell recognition assay measuring MHC ligand processing and presentation	http://purl.obolibrary.org/obo/OBI_1110125	assay measuring MHC ligand processing and presentation		A MHC ligand processing and presentation assay in which the presence of a specific ligand in an eluate is detected using the response of T cells that are known to be monospecific for that ligand as a readout.
http://purl.obolibrary.org/obo/OBI_0001470	epitope specific interleukin-17F production by T cells	http://purl.obolibrary.org/obo/GO_0097088	interleukin-17F production		A process of interleukin-17F production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001471	T cell epitope specific immune intervention	http://purl.obolibrary.org/obo/OBI_0001192	epitope specific immune intervention		An epitope specific immune intervention in which the induced response targets a T cell epitope
http://purl.obolibrary.org/obo/OBI_0001472	specimen with known storage state	http://purl.obolibrary.org/obo/OBI_0100051	specimen		A specimen for which it is known whether it has been subjected to storage of a specified type.
http://purl.obolibrary.org/obo/OBI_0001473	in vivo assay measuring T cell epitope specific protection after tumor burden challenge	http://purl.obolibrary.org/obo/OBI_0003461	in vivo assay measuring T cell epitope specific protection from tumor challenge		An in vivo assay measuring T cell epitope specific protection from tumor challenge using tumor burden.
http://purl.obolibrary.org/obo/OBI_0001474	lowess group transformation	http://purl.obolibrary.org/obo/OBI_0001477	lowess transformation		A lowess transformation where a potentially different normalization curve is generated and used for two or more groups (delineated by some criteria); criteria could include blocks (e.g. print-tip groups) on an array, or the day on which mass spectrometry was performed.
http://purl.obolibrary.org/obo/OBI_0001475	in vivo assay measuring T cell epitope specific protection from infectious challenge based on pathogen burden	http://purl.obolibrary.org/obo/OBI_0003460	in vivo assay measuring T cell epitope specific protection from pathogen challenge		An in vivo assay measuring T cell epitope specific protection from pathogen challenge using pathogen burden.
http://purl.obolibrary.org/obo/OBI_0001476	phage display binding assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay in which a collection of phages expressing a library of different peptides or protein fragnments is used to infect cells, followed by screening for cells that bind a protein of interest, and identifiying the sequence of infecting phages to determine a suitable binding partner.
http://purl.obolibrary.org/obo/OBI_0001477	lowess transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A data transformation of normalizing ratio data by using a locally weighted polynomial regression (typically after a log transformation). The regression can be performed on log ratios resulting from the relation of two data sets versus the average log intensity data from the same two data sets or it can be performed on raw or log transformed values from one data set versus values from another. The goal could be to remove intensity-dependent dye-specific effects from the set of pair wise ratios. This method can be applied globally, or limited by one or more specified criteria.
http://purl.obolibrary.org/obo/OBI_0001478	mass spectrometry assay measuring MHC ligand processing and presentation	http://purl.obolibrary.org/obo/OBI_1110125	assay measuring MHC ligand processing and presentation		A MHC ligand processing and presentation assay that uses a mass spectrometry assay to identify eluted ligands
http://purl.obolibrary.org/obo/OBI_0001480	phage display library panning	http://purl.obolibrary.org/obo/OBI_0000094	material processing		Phage display library panning is a process in which a diverse collection of phages encoding peptides or proteins are screened and the ones encoding active peptides/proteins are selected in an iterative process similar to natural selection.
http://purl.obolibrary.org/obo/OBI_0001481	lowess global transformation	http://purl.obolibrary.org/obo/OBI_0001477	lowess transformation		A lowess transformation where the same normalization curve is used for all members of the data set; e.g. Features on an array, picked spots on a gel, or measured metabolites in a sample.
http://purl.obolibrary.org/obo/OBI_0001482	intracellular cytokine staining assay measuring epitope specific transforming growth factor-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001264	assay measuring epitope specific transforming growth factor-beta production by T cells		A flow cytometry assay that detects transforming growth factor-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001483	cell collecting	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		A planned process that collects cells from culture.
http://purl.obolibrary.org/obo/OBI_0001484	assay measuring T cell epitope specific in vivo activity	http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding		A T cell epitope dependent biological activity determination assay that uses an in vivo intervention experiment.
http://purl.obolibrary.org/obo/OBI_0001485	purified MHC molecule preparation	http://purl.obolibrary.org/obo/OBI_0001633	purified material		A mixture containing MHC molecules that was purified to remove non-MHC molecular entities.
http://purl.obolibrary.org/obo/OBI_0001487	B cell epitope specific immune intervention	http://purl.obolibrary.org/obo/OBI_0001192	epitope specific immune intervention		An epitope specific immune intervention in which the induced response targets a B cell epitope
http://purl.obolibrary.org/obo/OBI_0001489	mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from cellular MHC	http://purl.obolibrary.org/obo/OBI_0001478	mass spectrometry assay measuring MHC ligand processing and presentation		A mass spectrometry of MHC ligands assay that identifies eluted ligands from cell bound MHC.
http://purl.obolibrary.org/obo/OBI_0001490	cytometric bead array measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects granulocyte macrophage colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001491	binding assay using radioactivity detection	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay that uses radioactivity detection as an indicator of binding.
http://purl.obolibrary.org/obo/OBI_0001492	in vivo assay measuring T cell epitope specific protection based on survival	http://purl.obolibrary.org/obo/OBI_0003462	in vivo assay measuring T cell epitope specific protection from other challenge		An in vivo assay measuring T cell epitope specific protection from other challenge using survival.
http://purl.obolibrary.org/obo/OBI_0001493	cell bound MHC competitive binding assay of a MHC:ligand complex using T cell epitope recognition	http://purl.obolibrary.org/obo/OBI_0001550	assay measuring binding of a cell-bound-MHC:ligand complex		A cell bound MHC binding assay that uses a T cell epitope recognition assay.
http://purl.obolibrary.org/obo/OBI_0001494	linear amplification	http://purl.obolibrary.org/obo/OBI_0600058	enzymatic amplification		An enzymatic amplification which amplifies nucleic acid sequence by making many copies off the same template.
http://purl.obolibrary.org/obo/OBI_0001495	in vivo assay measuring epitope specific T cell helper activity	http://purl.obolibrary.org/obo/OBI_0001484	assay measuring T cell epitope specific in vivo activity		A T cell epitope dependent biological activity assay that detects the ability of epitope specific helper T cells to enhance either B cell or T cell adaptive immune response function.
http://purl.obolibrary.org/obo/OBI_0001496	intracellular cytokine staining assay measuring epitope specific interleukin-22 production by T cells	http://purl.obolibrary.org/obo/OBI_0001217	assay measuring epitope specific interleukin-22 production by T cells		A flow cytometry assay that detects interleukin-22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001497	assay measuring epitope specific perforin release by T cells	http://purl.obolibrary.org/obo/OBI_0001269	assay measuring epitope specific cytotoxic T cell degranulation		A T cell epitope specific cytotoxic T cell degranulation assay that detects perforin release by T cells.
http://purl.obolibrary.org/obo/OBI_0001498	atmosphere	http://purl.obolibrary.org/obo/OBI_0000997	growth environment		A growth environment pertaining to the atmospheric conditions that is used to culture or grow an organism.
http://purl.obolibrary.org/obo/OBI_0001499	binding assay using fluorescence detection	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay that uses fluorescence detection as an indicator of binding.
http://purl.obolibrary.org/obo/OBI_0001500	coelution assay measuring MHC ligand processing and presentation using T cell recognition of HPLC fractionated eluate compared to synthetic ligand	http://purl.obolibrary.org/obo/OBI_1110125	assay measuring MHC ligand processing and presentation		A MHC ligand processing and presentation assay in which an HPL chromatography is run to separate an input mixture of ligands eluted from MHC into fractions. These fractions are tested for recognition by T cells and compared to the recognition of a synthetic ligand that is presumed to be the recognized epitope. Identical HPLC fractionation and T cell recognition patterns confirm that the specific ligand was presented by MHC molecules.
http://purl.obolibrary.org/obo/OBI_0001501	fluorescence detection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay in which a material's fluorescence is determined.
http://purl.obolibrary.org/obo/OBI_0001502	epitope specific perforin production by T cells	http://purl.obolibrary.org/obo/GO_0035944	perforin production		The production of perforin, an immune mediator molecule involved in T cell degranulation,  resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001503	MHC protein complex binding to ligand	http://purl.obolibrary.org/obo/OBI_0001588	binding		The process in which a ligand binds to an MHC molecule to form a stable complex.
http://purl.obolibrary.org/obo/OBI_0001504	dissection	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A planned process that separates and isolates tissues for surgical purposes, or for the analysis or study of their structures.
http://purl.obolibrary.org/obo/OBI_0001505	purification	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		A planned process to separate a material entity into different compositions of which one or more have are purified fractions that contain higher concentration of a desired component, while others contain impurities and are not of interest
http://purl.obolibrary.org/obo/OBI_0001506	specimen with pre- or post-mortem status	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism.
http://purl.obolibrary.org/obo/OBI_0001507	in vivo assay measuring T cell epitope specific treatment of disease	http://purl.obolibrary.org/obo/OBI_0001484	assay measuring T cell epitope specific in vivo activity		An efficacy of T cell epitope intervention experiment that detects a decrease in disease.
http://purl.obolibrary.org/obo/OBI_0001510	mass spectrometry assay measuring MHC ligand processing and presentation of MHC ligands eluted from secreted MHC	http://purl.obolibrary.org/obo/OBI_0001478	mass spectrometry assay measuring MHC ligand processing and presentation		A mass spectrometry of MHC ligands that identifies eluted ligands from secreted MHC.
http://purl.obolibrary.org/obo/OBI_0001511	disposition to be a product of antigen processing and presentation	http://purl.obolibrary.org/obo/BFO_0000016	disposition		A disposition of a material entity to be presented by MHC molecules on the cell surface as a result of antigen processing by an antigen presenting cell.
http://purl.obolibrary.org/obo/OBI_0001512	cytometric bead array assay measuring epitope specific interleukin-17A production by T cells	http://purl.obolibrary.org/obo/OBI_0001773	assay measuring epitope specific interleukin-17A production by T cells		A cytometric bead array assay that detects interleukin-17A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001513	radioactivity detection assay measuring competitive binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001555	assay measuring binding of a purified-MHC:ligand complex		A radioactivity detection assay that detects loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001514	minimal inhibitory concentration	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		A scalar measurement datum that indicates the lowest concentration at which a specific compound significantly inhibits a process from occurring compared to in the absence of the compound.
http://purl.obolibrary.org/obo/OBI_0001515	material maintenance service	http://purl.obolibrary.org/obo/OBI_0001528	material service		A material processing service in which a service provider makes physical modifications to a specified input material, such that at least one of the specified outputs of this process is a modified version of a specified input material.
http://purl.obolibrary.org/obo/OBI_0001516	radioactivity detection assay measuring half maximal effective concentration [EC50] to determine direct binding of a cell-lysate-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001991	assay measuring the half maximal effective concentration [EC50] of a MHC:ligand complex		A radioactivity detection assay that measures half maximal effective concentration (EC50) to detect the direct binding of a cell-lysate-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001517	radioactivity detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001992	assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex		A radioactivity detection assay that measures half maximal inhibitory concentration (IC50) to detect the loss of binding of a known reference ligand to cell-bound-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001518	epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells	http://purl.obolibrary.org/obo/GO_0072535	tumor necrosis factor (ligand) superfamily member 11 production		A process of tumor necrosis factor (ligand) superfamily member 11 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001519	fluorescence detection assay measuring direct binding of a cell-lysate-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001579	assay measuring binding of a cell-lysate-MHC:ligand complex		A fluorescence detection assay that detects direct binding of a cell-lysate-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001520	fluorescence detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001992	assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex		A fluorescence detection assay that measures half maximal inhibitory concentration (IC50) to detect the loss of binding of a known reference ligand to cell-bound-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001521	ELISA measuring epitope specific granulocyte colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001600	assay measuring epitope specific granulocyte colony stimulating factor production by T cells		An enzyme-linked immunosorbent assay that detects granulocyte colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001522	sequence assembly algorithm	http://purl.obolibrary.org/obo/IAO_0000064	algorithm		An algorithm used to assemble individual sequence reads into larger contiguous sequences (contigs).  Assembly details include but are not limited to assembler type (overlap-layout-consensus, deBruijn), assembler version, and any relevant quality control information such as per cent known genes/ESTs captured.
http://purl.obolibrary.org/obo/OBI_0001523	cytometric bead array assay measuring epitope specific interleukin-17F production by T cells	http://purl.obolibrary.org/obo/OBI_0001772	assay measuring epitope specific interleukin-17F production by T cells		A cytometric bead array assay that detects interleukin-17F production by T cells.
http://purl.obolibrary.org/obo/OBI_0001524	fluorescence detection assay measuring equilibrium association constant [KA] to determine direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001987	assay measuring the association constant [KA] of a MHC:ligand complex		A fluorescence detection assay that measures equilibrium association constant (KA) to detect the direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001525	PDB file	http://purl.obolibrary.org/obo/OBI_0001155	3D structural organization datum		A 3d structural organization datum capturing the results of X-ray crystallography or NMR experiment that is formatted as specified by the Protein Databank (http://www.wwpdb.org/docs.html). A PDB file can describe the structure of multiple molecules, each of which has a different chain identifier assigned.
http://purl.obolibrary.org/obo/OBI_0001526	epitope specific interleukin-17A production by T cells	http://purl.obolibrary.org/obo/GO_0097087	interleukin-17A production		A process of interleukin-17A production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001527	support service	http://purl.obolibrary.org/obo/OBI_0001173	service		A service  in which the service provider assists the consumer in activities directly or indirectly associated with the production and analysis of experimental research data.
http://purl.obolibrary.org/obo/OBI_0001528	material service	http://purl.obolibrary.org/obo/OBI_0001173	service		A service which has a material entity as specified input and/or specified output.
http://purl.obolibrary.org/obo/OBI_0001529	data analysis service	http://purl.obolibrary.org/obo/OBI_0001530	data service		A service in which a service consumer provides some input data and a service provider transforms, models, or interprets the input data and returns this generated data as output.
http://purl.obolibrary.org/obo/OBI_0001530	data service	http://purl.obolibrary.org/obo/OBI_0001173	service		A service that has some information content entity as input and output.
http://purl.obolibrary.org/obo/OBI_0001531	fluorescence detection assay measuring half life to determine direct binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001990	assay measuring the half life of a MHC:ligand complex		A fluorescence detection assay that measures half life to detect the direct binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001532	cytometric bead array assay measuring epitope specific interleukin-9 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001533	data storage service	http://purl.obolibrary.org/obo/OBI_0001530	data service		A storage service in which a service consumer provides data as input which a service provider stores and returns as output in its original form.
http://purl.obolibrary.org/obo/OBI_0001534	fluorescence detection assay measuring competitive binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001555	assay measuring binding of a purified-MHC:ligand complex		A fluorescence detection assay that detects loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001535	epitope specific interleukin-7 production by T cells	http://purl.obolibrary.org/obo/GO_0032636	interleukin-7 production		A process of interleukin-7 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001536	equilibrium dissociation constant (KD)	http://purl.obolibrary.org/obo/OBI_0001144	binding constant		A binding constant defined as the ratio of kon over koff (on-rate of binding divided by off-rate)
http://purl.obolibrary.org/obo/OBI_0001537	fluorescence detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001988	assay measuring the dissociation constant [KD] of a MHC:ligand complex		A fluorescence detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001538	training service	http://purl.obolibrary.org/obo/OBI_0001173	service		A service  in which the service provider offers educational materials or events, such as courses, workshops or graduate programs, to the service consumer.
http://purl.obolibrary.org/obo/OBI_0001539	fluorescence detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001988	assay measuring the dissociation constant [KD] of a MHC:ligand complex		A fluorescence detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to cell-bound-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001540	obsolete T cell recognition of eluted MHC ligand assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An assay that identifies an MHC ligand using a T cell response assay as a readout
http://purl.obolibrary.org/obo/OBI_0001541	fluorescence detection assay measuring binding on rate [kon] to determine direct binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001994	assay measuring the MHC ligand binding on rate [kon] of a MHC:ligand complex		A fluorescence detection assay measuring binding on rate (kon) to detect direct binding of a purified-MHC:ligand complex.
http://purl.obolibrary.org/obo/OBI_0001542	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-13 production by T cells	http://purl.obolibrary.org/obo/OBI_0001251	assay measuring epitope specific interleukin-13 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-13 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001543	fluorescence detection assay measuring equilibrium dissociation constant [KD] to determine direct binding of a purified-MHC:ligand complex approximated by EC50	http://purl.obolibrary.org/obo/OBI_0001988	assay measuring the dissociation constant [KD] of a MHC:ligand complex		A fluorescence detection assay that measures equilibrium dissociation constant (KD) to detect direct binding of a purified-MHC molecule with a ligand and provides EC50 values determined under assay conditions where the EC50 approximates a KD value.
http://purl.obolibrary.org/obo/OBI_0001544	radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a cell-lysate-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001988	assay measuring the dissociation constant [KD] of a MHC:ligand complex		A radioactivity detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to cell-lysate-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001545	intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001333	assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells		A flow cytometry assay that detects macrophage inflammatory protein-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001546	comparative phenotypic assessment	http://purl.obolibrary.org/obo/OBI_0001834	drawing a conclusion		Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms to make a conclusion about a phenotypic difference
http://purl.obolibrary.org/obo/OBI_0001547	material analysis service	http://purl.obolibrary.org/obo/OBI_0001528	material service		A service in which a service consumer provides some input material and a service provider performs some analysis of this material to generate data that is returned to the service consumer.
http://purl.obolibrary.org/obo/OBI_0001548	equilibrium association constant (KA)	http://purl.obolibrary.org/obo/OBI_0001144	binding constant		A binding constant defined as the ratio of koff over kon (off-rate of binding divided by on-rate)
http://purl.obolibrary.org/obo/OBI_0001549	radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001988	assay measuring the dissociation constant [KD] of a MHC:ligand complex		A radioactivity detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to cell-bound-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001550	assay measuring binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0002072	assay measuring qualitative binding of a MHC:ligand complex		A qualitative binding assay that detects the binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001551	access service	http://purl.obolibrary.org/obo/OBI_0001173	service		A service in which a service consumer receives the right to use a resource (instrument, database, software, etc) that is owned or managed by a service provider.  Ownership of the accessed resource remains with the service provider during and after provision of service.
http://purl.obolibrary.org/obo/OBI_0001552	intracellular cytokine staining assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells	http://purl.obolibrary.org/obo/OBI_0001607	assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells		A flow cytometry assay that detects tumor necrosis factor (ligand) superfamily member 11 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001553	assay measuring a binding constant of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0003145	assay measuring quantitative binding of a MHC:ligand complex		A MHC:ligand binding assay that measures a binding constant.
http://purl.obolibrary.org/obo/OBI_0001554	rate measurement datum	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		A scalar measurement datum that represents the number of events occuring over a time interval
http://purl.obolibrary.org/obo/OBI_0001555	assay measuring binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0002072	assay measuring qualitative binding of a MHC:ligand complex		A qualitative binding assay that detects the binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001556	radioactivity detection assay measuring direct binding of a cell-lysate-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001579	assay measuring binding of a cell-lysate-MHC:ligand complex		A radioactivity detection assay that detects direct binding of a cell-lysate-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001557	material storage service	http://purl.obolibrary.org/obo/OBI_0001515	material maintenance service		A storage service in which a service consumer provides some material as input which a service provider stores and returns as output.
http://purl.obolibrary.org/obo/OBI_0001558	radioactivity detection assay measuring half life to determine direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001990	assay measuring the half life of a MHC:ligand complex		A radioactivity detection assay that measures half life to detect the direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001559	fluorescence detection assay measuring half life to determine direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001990	assay measuring the half life of a MHC:ligand complex		A fluorescence detection assay that measures half life to detect the direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001560	obsolete cell lysate MHC binding constant determination assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An assay that measures the affinity of a ligand to a MHC in a cell lysate preparation and that quantifies the affinity with a binding constant.
http://purl.obolibrary.org/obo/OBI_0001561	fluorescence detection assay measuring half maximal effective concentration [EC50] to determine direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001991	assay measuring the half maximal effective concentration [EC50] of a MHC:ligand complex		A fluorescence detection assay that measures half maximal effective concentration (EC50) to detect direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001562	intracellular cytokine staining assay measuring epitope specific interleukin-17F production by T cells	http://purl.obolibrary.org/obo/OBI_1110178	intracellular cytokine staining assay measuring epitope specific interleukin-17 production by T cells		A flow cytometry assay that detects interleukin-17F production by T cells.
http://purl.obolibrary.org/obo/OBI_0001563	material processing service	http://purl.obolibrary.org/obo/OBI_0001528	material service		A service in which a service provider makes physical changes to a specified input material entity with the objective of producing a new material entity form input materials, or modifying the input material entity, and returning this as output to the service consumer.
http://purl.obolibrary.org/obo/OBI_0001564	radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a purified-MHC:ligand complex approximated by IC50	http://purl.obolibrary.org/obo/OBI_0001989	radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a purified-MHC:ligand complex		A radioactivity detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation and provides IC50 values determined under assay conditions where the IC50 approximates a KD value.
http://purl.obolibrary.org/obo/OBI_0001565	radioactivity detection assay measuring half life to determine direct binding of a cell-lysate-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001990	assay measuring the half life of a MHC:ligand complex		A radioactivity detection assay that measures half life to detect the direct binding of a cell-lysate-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001567	radioactivity detection assay measuring binding off rate [koff] to determine direct binding of a cell-lysate-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001993	assay measuring the off rate measurement [koff] of a MHC:ligand complex		A radioactivity detection assay that measures binding off rate [koff] to detect direct binding of a cell-lysate-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001568	radioactivity detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001992	assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex		A radioactivity detection assay that measures half maximal inhibitory concentration (IC50) to detect the loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001569	fluorescence detection assay measuring binding off rate [koff] to determine direct binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001993	assay measuring the off rate measurement [koff] of a MHC:ligand complex		A fluorescence detection assay that measures binding off rate [koff] to detect direct binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001570	assay measuring epitope specific vascular endothelial growth factor production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects vascular endothelial growth factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001571	equilibrium dissociation constant (KD) approximated by IC50	http://purl.obolibrary.org/obo/OBI_0003144	IC50 binding datum		A measurement of an IC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium, there is a single population of sites on the receptor that competitor and ligand are binding to, and the concentration of the receptor must be much less than the KD for the competitor and the ligand.  In this case, according to Cheng and Prussoff, KD = IC50 / (1 + Lstot / KDs), in which Lstot is the total concentration of the labeled competitor and KDs is the KD value of that competitor.
http://purl.obolibrary.org/obo/OBI_0001572	obsolete cell bound MHC binding constant determination assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An assay that measures the affinity of a ligand to MHC moleculs bound to the cell surface and that quantifies the affinity with a binding constant.
http://purl.obolibrary.org/obo/OBI_0001573	DNA sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		A sequence data item that is about the primary structure of DNA
http://purl.obolibrary.org/obo/OBI_0001574	obsolete cell lysate MHC competitive binding assay using radioactivity detection	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		competitive inhibition of binding assay measuring MHC ligand binding by radioactivity detection using MHC derived from a cell lysate
http://purl.obolibrary.org/obo/OBI_0001575	assigning gene property based on phenotypic assessment	http://purl.obolibrary.org/obo/OBI_0000338	drawing a conclusion based on data		Interpreting data from assays that evaluate the qualities or dispositions inhering in an organism or organism part and comparing it to data from other organisms that have a defined genetic difference, and assigning a property to the product of the targeted gene as a result.
http://purl.obolibrary.org/obo/OBI_0001576	obsolete purified MHC binding constant determination assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An assay that measures the affinity of a ligand to a purified MHC complex preparation and that quantifies the affinity with a binding constant.
http://purl.obolibrary.org/obo/OBI_0001577	cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-22 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001578	ELISA measuring epitope specific vascular endothelial growth factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001570	assay measuring epitope specific vascular endothelial growth factor production by T cells		An enzyme-linked immunosorbent assay that detects vascular endothelial growth factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001579	assay measuring binding of a cell-lysate-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0002072	assay measuring qualitative binding of a MHC:ligand complex		A qualitative binding assay that detects the binding of a cell-lysate-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001580	material transport service	http://purl.obolibrary.org/obo/OBI_0001528	material service		A service in which a service provider facilitates the transport of some material entity to a specified destination for the service consumer.
http://purl.obolibrary.org/obo/OBI_0001581	equilibrium dissociation constant (KD) approximated by EC50	http://purl.obolibrary.org/obo/OBI_0003143	EC50 binding datum		A measurement of an EC50 value under specific assay conditions approximates KD, namely the binding reaction is at an equilibrium,  and the concentration of the receptor must be much less than the KD for the ligand.
http://purl.obolibrary.org/obo/OBI_0001582	obsolete cell bound MHC direct binding assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		direct binding assay measuring MHC ligand binding using MHC derived from a cell
http://purl.obolibrary.org/obo/OBI_0001583	half life of binding datum	http://purl.obolibrary.org/obo/OBI_0001171	half life datum (t 1/2)		A half life datum of the time it takes for 50% of bound complexes in an ensemble to disassociate in absence of re-association.
http://purl.obolibrary.org/obo/OBI_0001584	phage display binding assay measuring binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001555	assay measuring binding of a purified-MHC:ligand complex		A phage display binding assay that detects direct binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001585	cytometric bead array assay measuring epitope specific interleukin-7 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-7 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001586	radioactivity detection assay measuring half life to determine direct binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001990	assay measuring the half life of a MHC:ligand complex		A radioactivity detection assay that measures half life to detect the direct binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001587	assay measuring epitope specific interleukin-7 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-7 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001588	binding	http://purl.obolibrary.org/obo/GO_0008150	biological process		The process of material entities forming complexes.
http://purl.obolibrary.org/obo/OBI_0001589	intracellular cytokine staining assay measuring epitope specific interleukin-17A production by T cells	http://purl.obolibrary.org/obo/OBI_1110178	intracellular cytokine staining assay measuring epitope specific interleukin-17 production by T cells		A flow cytometry assay that detects interleukin-17A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001590	fluorescence detection assay measuring direct binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001555	assay measuring binding of a purified-MHC:ligand complex		A fluorescence detection assay that detects direct binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001591	direct binding assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay that measures the formation or disassociation of a complex of 2 material entities directly without use of a competitve ligand.
http://purl.obolibrary.org/obo/OBI_0001592	fluorescence detection assay measuring half maximal effective concentration [EC50] to determine direct binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001991	assay measuring the half maximal effective concentration [EC50] of a MHC:ligand complex		A fluorescence detection assay that measures half maximal effective concentration (EC50) to detect direct binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001593	competitive inhibition of binding assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay that detects the inhibition of binding between 2 material entities known to form a complex by the addition of a third material entity of interest. Inhibition of binding between the 2 materials reflects binding by the third material.
http://purl.obolibrary.org/obo/OBI_0001594	fluorescence detection assay measuring competitive binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001550	assay measuring binding of a cell-bound-MHC:ligand complex		A fluorescence detection assay that detects loss of binding of a known reference ligand to cell-bound-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001595	X-ray crystallography assay determining the 3D structure of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0002050	3D molecular structure determination assay of a MHC:ligand complex		A X-ray crystallography 3D molecular structure determination assay that characterizes the 3-dimensional molecular structure of a MHC:ligand complex.
http://purl.obolibrary.org/obo/OBI_0001596	PDB file chain	http://purl.obolibrary.org/obo/OBI_0001155	3D structural organization datum		A 3D structural organization datum that is part of a PDB file and has a specific chain identifier that identifies the entire information on a subset of the material entities.
http://purl.obolibrary.org/obo/OBI_0001597	cell bound MHC competitive binding assay measuring half maximal inhibitory concentration [IC50] of a MHC:ligand complex using T cell epitope recognition	http://purl.obolibrary.org/obo/OBI_0001992	assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex		A cell bound MHC ligand binding half maximal inhibitory concentration (IC50) determination assay that uses a T cell epitope recognition assay to measure ligand binding.
http://purl.obolibrary.org/obo/OBI_0001598	data maintenance service	http://purl.obolibrary.org/obo/OBI_0001530	data service		A maintenance service in which a service provider actively manages or maintains data or a database for the service consumer.  Maintenance of the data is performed to maintain its integrity or enhance its quality or utility for the consumer, but new data is not generated as a result of the maintenance.
http://purl.obolibrary.org/obo/OBI_0001599	radioactivity detection assay measuring competitive binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001550	assay measuring binding of a cell-bound-MHC:ligand complex		A radioactivity detection assay that detects loss of binding of a known reference ligand to cell-bound-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001600	assay measuring epitope specific granulocyte colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects granulocyte colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001601	cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-21 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001602	radioactivity detection assay measuring direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001550	assay measuring binding of a cell-bound-MHC:ligand complex		A radioactivity detection assay that detects direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001603	binding off rate measurement datum (koff)	http://purl.obolibrary.org/obo/OBI_0001554	rate measurement datum		A rate measurement datum of how quickly bound complexes disassociate
http://purl.obolibrary.org/obo/OBI_0001604	fluorescence detection assay measuring 50% dissociation of binding temperature [Tm] of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0003145	assay measuring quantitative binding of a MHC:ligand complex		A fluorescence detection assay that measures the 50% dissociation of binding temperature of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001605	binding on rate measurement datum (kon)	http://purl.obolibrary.org/obo/OBI_0001554	rate measurement datum		A rate measurement datum of how quickly bound complexes form
http://purl.obolibrary.org/obo/OBI_0001606	fluorescence detection assay measuring direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001550	assay measuring binding of a cell-bound-MHC:ligand complex		A fluorescence detection assay that detects direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001607	assay measuring epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells	http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		An assay of epitope specific tumor necrosis factor (ligand) superfamily member 11 production by T cells that detects tumor necrosis factor production.
http://purl.obolibrary.org/obo/OBI_0001608	radioactivity detection assay measuring direct binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001555	assay measuring binding of a purified-MHC:ligand complex		A radioactivity detection assay that detects direct binding of a purified-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001609	intracellular cytokine staining assay measuring epitope specific interleukin-8 production by T cells	http://purl.obolibrary.org/obo/OBI_0001218	assay measuring epitope specific interleukin-8 production by T cells		A flow cytometry assay that detects interleukin-8 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001610	cytometric bead array assay measuring epitope specific intracellular cytokine staining (ICS) IL-23 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-23 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001611	obsolete purified MHC direct binding assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		direct binding assay measuring MHC ligand binding using MHC derived from a purified MHC molecule preparation
http://purl.obolibrary.org/obo/OBI_0001612	epitope specific vascular endothelial growth factor production by T cells	http://purl.obolibrary.org/obo/GO_0010573	vascular endothelial growth factor production		A process of vascular endothelial growth factor production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001613	fluorescence detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001992	assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex		A fluorescence detection assay that measures half maximal inhibitory concentration (IC50) to detect the loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001614	GenBank ID	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol		A CRID symbol uniquely indentifies the submitted GeneBank sequence record.
http://purl.obolibrary.org/obo/OBI_0001615	investigation description	http://purl.obolibrary.org/obo/OBI_0001898	comment on investigation		A textual entity that describes an investigation.
http://purl.obolibrary.org/obo/OBI_0001618	average depth of sequence coverage	http://purl.obolibrary.org/obo/OBI_0000679	average value		An average value of the depth of sequence coverage based both on external (e.g. Cot-based size estimates) and internal (average coverage in the assembly) measures of genome size.
http://purl.obolibrary.org/obo/OBI_0001622	investigation title	http://purl.obolibrary.org/obo/OBI_0001898	comment on investigation		A textual entity that denotes an investigation.
http://purl.obolibrary.org/obo/OBI_0001623	organism species detection objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		A biological feature identification objective to identify the organism species in a specimen.
http://purl.obolibrary.org/obo/OBI_0001625	sequence annotation algorithm	http://purl.obolibrary.org/obo/IAO_0000064	algorithm		An algorithm used to identify sequence features (e.g. protein coding regions) in the assembled contig sequence.  This may also include a description of any manual curation that may have generated or validated the annotation.
http://purl.obolibrary.org/obo/OBI_0001627	country name	http://purl.obolibrary.org/obo/IAO_0000300	textual entity		A textual entity that denotes a geographic location that is a site or part of a site that is identified as a country in the political geography.
http://purl.obolibrary.org/obo/OBI_0001628	investigation identifier	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol		A CRID symbol used to identify an investigation.
http://purl.obolibrary.org/obo/OBI_0001629	grant identifier	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol		A CRID symbol used to identify a grant.
http://purl.obolibrary.org/obo/OBI_0001630	analytical chromatography	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that uses a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials and thereby detect its presence in an input material.
http://purl.obolibrary.org/obo/OBI_0001631	electron microscopy imaging assay	http://purl.obolibrary.org/obo/OBI_0002119	microscopy assay		An imaging assay in which an electrons are used to probe the density, shape and composition of an input material which are detected in an electron microscope and utilized to produce an image of the material.
http://purl.obolibrary.org/obo/OBI_0001632	immuno staining assay	http://purl.obolibrary.org/obo/OBI_0600017	assay detecting a molecular label		A assay detecting a molecular label assay in which the label is attached to an antibody so that substances are marked based on the antibody's binding specificity.
http://purl.obolibrary.org/obo/OBI_0001633	purified material	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A material entity that is generated by a purification process in which an input material is separated to obtain a fraction with a higher concentration of a desired component
http://purl.obolibrary.org/obo/OBI_0001634	calorimetric binding assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay in which the heat generated or absorbed during a binding event is measured, which allows determination of binding constants, reaction stoichiometry, enthalpy and entropy.
http://purl.obolibrary.org/obo/OBI_0001635	antibody binding detection by fluorescence quenching	http://purl.obolibrary.org/obo/OBI_0001979	fluorescence quenching binding assay		A binding assay in which affinity is measured by detecting a change in fluorescence (usually quenching) that occurs upon binding of the antibody to the ligand. The fluorescent signal that is affected by binding is either from an exogenous fluorophore attached to the ligand, or is the intrisic fluorescence of aromatic (tryptophan) residues on the binding site of the antibody (no conjugated fluorophore necessary) or, less commonly, on the ligand binding region (epitope).
http://purl.obolibrary.org/obo/OBI_0001636	grant	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification of organization A to give money to organization B so that B conducts investigations. Organization A has funder role and Organization B has research organization role.
http://purl.obolibrary.org/obo/OBI_0001638	antigen inhibition assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex approximated by IC50	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		A B cell epitope equilibrium dissociation constant (KD) assay that provides IC50 values determined under assay conditions where the IC50 approximates a KD value using a B cell epitope antigen inhibition of binding assay.
http://purl.obolibrary.org/obo/OBI_0001639	assay measuring epitope specific Ig-mediated histamine release	http://purl.obolibrary.org/obo/OBI_0001704	assay measuring epitope specific activation of additional immune response in vitro		A B cell epitope specific activation of additional immune response assay that detects histamine release in vitro.
http://purl.obolibrary.org/obo/OBI_0001640	assay measuring epitope specific immunoglobulin-mediated antigen activation	http://purl.obolibrary.org/obo/OBI_0001706	assay measuring biological activity resulting from B cell epitope:antibody binding		A B cell epitope dependent biological activity determination assay that detects antigen activation.
http://purl.obolibrary.org/obo/OBI_0001641	assay measuring epitope specific complement-dependent cytotoxicity	http://purl.obolibrary.org/obo/OBI_0001704	assay measuring epitope specific activation of additional immune response in vitro		A B cell epitope specific activation of additional immune response assay that detects complement-dependent cytotoxicity in vitro .
http://purl.obolibrary.org/obo/OBI_0001642	assay measuring epitope specific antibody-dependent cellular cytotoxicity	http://purl.obolibrary.org/obo/OBI_0001704	assay measuring epitope specific activation of additional immune response in vitro		A B cell epitope specific activation of additional immune response assay that detects antibody-dependent cellular cytotoxicity in vitro.
http://purl.obolibrary.org/obo/OBI_0001643	assay measuring epitope specific immunoglobulin-mediated neutralization	http://purl.obolibrary.org/obo/OBI_0001706	assay measuring biological activity resulting from B cell epitope:antibody binding		A B cell epitope dependent biological activity determination assay that detects neutralization of the antigen.
http://purl.obolibrary.org/obo/OBI_0001644	assay measuring epitope specific opsonization	http://purl.obolibrary.org/obo/OBI_0001704	assay measuring epitope specific activation of additional immune response in vitro		A B cell epitope specific activation of additional immune response assay that detects opsonization in vitro .
http://purl.obolibrary.org/obo/OBI_0001645	calorimetry assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A calorimetric binding assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001646	electron microscopy assay determining the 3D structure of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0003118	electron-microscopy 3D molecular structure determination assay		An electron-microscopy 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a B cell epitope:antibody complex
http://purl.obolibrary.org/obo/OBI_0001647	NMR assay determining the 3D structure of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001721	3D molecular structure determination assay of an antigen:antibody complex		A nuclear magnetic resonance 3D molecular structure determination assay that characterizes the 3-dimensional structure of a B cell epitope:antibody complex.
http://purl.obolibrary.org/obo/OBI_0001648	cross blocking assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A cross-blocking assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001649	RIA measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A radio immuno assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001650	immunoblot assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001978	immunoblot assay		An immunoblot assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001651	plasmon resonance assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A surface plasmon resonance binding assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001652	immuno staining assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		An immuno staining assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001653	immunoprecipitation assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		An immunoprecipitation assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001654	mass spectrometry assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A mass spectrometry assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001655	phage display assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A phage display binding assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001656	electron microscopy assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		An electron microscopy imaging assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001657	ELISA measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		An enzyme-linked immunosorbent assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001658	ELISPOT assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001659	flow cytometry assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A flow cytometry assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001660	intracellular material detection assay measuring epitope specific granzyme A release by T cells	http://purl.obolibrary.org/obo/OBI_0001809	assay measuring epitope specific granzyme A release by T cells		A flow cytometry assay that detects epitope specific granzyme A release by T cells.
http://purl.obolibrary.org/obo/OBI_0001661	chromatography assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		An analytical chromatography assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001662	NMR assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A B cell epitope qualitative binding to antibody assay that uses a nuclear magnetic resonance assay.
http://purl.obolibrary.org/obo/OBI_0001663	ELISA measuring epitope specific granulysin release by T cells	http://purl.obolibrary.org/obo/OBI_0001810	assay measuring epitope specific granulysin release by T cells		An enzyme-linked immunosorbent assay that detects epitope specific granulysin release by T cells.
http://purl.obolibrary.org/obo/OBI_0001664	intracellular material detection assay measuring epitope specific granulysin release by T cells	http://purl.obolibrary.org/obo/OBI_0001810	assay measuring epitope specific granulysin release by T cells		A flow cytometry assay that detects epitope specific granulysin release by T cells.
http://purl.obolibrary.org/obo/OBI_0001665	fluorescence detection assay measuring binding off rate [koff] to determine direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001993	assay measuring the off rate measurement [koff] of a MHC:ligand complex		A fluorescence detection assay that measures binding off rate [koff] to detect direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001666	fluorescence detection assay measuring binding on rate [kon] to determine direct binding of a cell-bound-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001994	assay measuring the MHC ligand binding on rate [kon] of a MHC:ligand complex		A fluorescence detection assay that measures binding on rate (kon) to detect direct binding of a cell-bound-MHC molecule with a ligand.
http://purl.obolibrary.org/obo/OBI_0001667	fluorescence detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a purified-MHC:ligand complex approximated by IC50	http://purl.obolibrary.org/obo/OBI_0001613	fluorescence detection assay measuring half maximal inhibitory concentration [IC50] to determine competitive binding of a purified-MHC:ligand complex		A fluorescence detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation and provides IC50 values determined under assay conditions where the IC50 approximates a KD value.
http://purl.obolibrary.org/obo/OBI_0001668	split-ubiquitin assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		A binding assay that screens membrane soluble proteins by fusion of two integral membrane proteins (bait and prey) to two different ubiquitin moieties. One moiety is also fused to a transcription factor (TF) that can be cleaved off by ubiquitin specific proteases. Upon bait and prey interaction, Nub and Cub-moieties assemble, reconstituting the split-ubiquitin. The reconstituted split-ubiquitin molecule is recognized by ubiquitin specific proteases, which cleave off the reporter protein, allowing it to induce the transcription of reporter genes.
http://purl.obolibrary.org/obo/OBI_0001669	far-western blot assay	http://purl.obolibrary.org/obo/OBI_0001146	binding assay		An assay that measures protein-protein interactions by separating target proteins on an SDS-PAGE gel, transfering them to a solid substrate, hybridizing with a protein probe and visualizing bound proteins using a probe-directed antibody. This is a adaptation on the western blot assay.
http://purl.obolibrary.org/obo/OBI_0001672	gene knock-down assay	http://purl.obolibrary.org/obo/OBI_0003587	cell culture assay		An assay which transiently disrupts gene transcripts by expressing antisense RNA constructs or delivering RNA interfering molecules in cells.
http://purl.obolibrary.org/obo/OBI_0001675	ELISA measuring epitope specific interleukin-17A production by T cells	http://purl.obolibrary.org/obo/OBI_1110162	ELISA measuring epitope specific interleukin-17 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-17A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001676	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-7 production by T cells	http://purl.obolibrary.org/obo/OBI_0001587	assay measuring epitope specific interleukin-7 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-7 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001677	epitope specific granulysin production by T cells	http://purl.obolibrary.org/obo/GO_0036262	granulysin production		A process of granulysin production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001678	epitope specific granzyme A production by T cells	http://purl.obolibrary.org/obo/GO_0035746	granzyme A production		A process of granzyme A production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001683	chromosome organization assay by fluorescence in-situ hybridization	http://purl.obolibrary.org/obo/OBI_0001686	in-situ hybridization assay		An in-situ hybridization assay that uses fluorescence to detect chromosomal integrity
http://purl.obolibrary.org/obo/OBI_0001687	contact representative role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role inhering in a person who represents an institution, organization, or service provider and realized when communication is directed at them about the entity they represent.
http://purl.obolibrary.org/obo/OBI_0001689	cytochalasin-induced inhibition of actin polymerization assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay which uses compound cytochalasin (CHEBI: 23528) to block actin polymerization-dependent cell motility (GO:0070358) and actin filament polymerization (GO:0030041).
http://purl.obolibrary.org/obo/OBI_0001690	molecular function identification objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		is an objective specification which aims to discover molecular function realized by a molecular entity
http://purl.obolibrary.org/obo/OBI_0001691	cellular structure feature identification objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		is an objective specification which aims to discover cellular structure properties
http://purl.obolibrary.org/obo/OBI_0001692	in vivo assay measuring B cell epitope specific protection from fertility	http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity		An efficacy of B cell epitope intervention experiment that uses a epitope protection experiment based on reduction of fertility.
http://purl.obolibrary.org/obo/OBI_0001693	in vivo assay measuring B cell epitope specific tolerance induction	http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity		An efficacy of B cell epitope intervention experiment that uses a tolerance induction intervention experiment.
http://purl.obolibrary.org/obo/OBI_0001694	in vivo assay measuring B cell epitope specific induction of hypersensitivity	http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity		An efficacy of B cell epitope intervention experiment that detects a hypersensitivity response by monitoring skin reactions.
http://purl.obolibrary.org/obo/OBI_0001695	assay measuring epitope specific immune complex formation	http://purl.obolibrary.org/obo/OBI_0001704	assay measuring epitope specific activation of additional immune response in vitro		A B cell epitope specific activation of additional immune response assay that detects agglutination in vitro.
http://purl.obolibrary.org/obo/OBI_0001696	in vivo assay measuring B cell epitope specific protection based on survival	http://purl.obolibrary.org/obo/OBI_0003467	in vivo assay measuring B cell epitope specific protection from other challenge		An in vivo assay measuring B cell epitope specific protection from other challenge using survival.
http://purl.obolibrary.org/obo/OBI_0001697	in vivo assay measuring B cell epitope specific treatment of disease	http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity		An efficacy of B cell epitope intervention experiment that detects a decrease in disease.
http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity	http://purl.obolibrary.org/obo/OBI_0001706	assay measuring biological activity resulting from B cell epitope:antibody binding		A B cell epitope dependent biological activity determination assay that uses an in vivo intervention experiment.
http://purl.obolibrary.org/obo/OBI_0001700	immunoprecipitation assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay in which an input material is mixed with antibodies and bound antigen:antibody complexes are separated out using immunoprecipitation. Either the antibody has known specificy, and the antigen mixture is tested for the presence of a specific antigen, or the antigen solution is well defined and the antibody solution is tested for the presence of antigen specific antibodies.
http://purl.obolibrary.org/obo/OBI_0001701	antigen inhibition assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A B cell epitope qualitative binding to antibody assay that measures the ability of an antigen to inhibit antibody binding to a known ligand.
http://purl.obolibrary.org/obo/OBI_0001702	immunoglobulin binding to epitope	http://purl.obolibrary.org/obo/OBI_1110014	epitope binding by adaptive immune receptor		a process of an immunoglobulin complex binding to a material entity at the immunoglobulin complementarity determining region (CDR).
http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_1110127	assay measuring binding of a B cell epitope:antibody complex		An assay that detects the binding of an antigen with an antibody, and produces a qualitative measurement of the binding as an output.
http://purl.obolibrary.org/obo/OBI_0001704	assay measuring epitope specific activation of additional immune response in vitro	http://purl.obolibrary.org/obo/OBI_0001706	assay measuring biological activity resulting from B cell epitope:antibody binding		A B cell epitope dependent biological activity determination assay that detects secondary in vitro activity.
http://purl.obolibrary.org/obo/OBI_0001705	assay measuring epitope specific antigen inhibition of antibody activity	http://purl.obolibrary.org/obo/OBI_0001706	assay measuring biological activity resulting from B cell epitope:antibody binding		A B cell epitope dependent biological activity determination assay that detects inhibition of the antibody's activity by the antigen.
http://purl.obolibrary.org/obo/OBI_0001706	assay measuring biological activity resulting from B cell epitope:antibody binding	http://purl.obolibrary.org/obo/OBI_0003127	B cell epitope assay		A B cell epitope assay that measures the immune response process resulting from the binding of an antibody receptor to epitope or recognition of the epitope.
http://purl.obolibrary.org/obo/OBI_0001707	immunoglobulin mediated histamine release	http://purl.obolibrary.org/obo/GO_0008150	biological process		The release of histamine by cells stimulated through their Fc receptors which are loaded with immunoglobulins.
http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001709	assay measuring a binding constant of a B cell epitope:antibody complex		A B cell epitope binding constant determination assay that measures the dissociation constant KD.
http://purl.obolibrary.org/obo/OBI_0001709	assay measuring a binding constant of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0003146	assay measuring quantitative binding of an antigen:antibody complex		A B cell epitope recognition assay that quantitavely characterizes the binding of an antibody / BCR with a ligand by determining a binding constant.
http://purl.obolibrary.org/obo/OBI_0001710	in vivo assay measuring B cell epitope specific protection from challenge	http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity		An efficacy of B cell epitope intervention experiment that uses a epitope protection experiment.
http://purl.obolibrary.org/obo/OBI_0001711	in vivo assay measuring B cell epitope specific disease exacerbation	http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity		An efficacy of B cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment.
http://purl.obolibrary.org/obo/OBI_0001712	obsolete B cell epitope direct binding assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A direct binding assay using a assay
http://purl.obolibrary.org/obo/OBI_0001713	B cell epitope specific opsonization	http://purl.obolibrary.org/obo/GO_0008228	opsonization		opsonization resulting from antibody binding to epitope
http://purl.obolibrary.org/obo/OBI_0001714	B cell epitope specific immunoglobulin-mediated neutralization	http://purl.obolibrary.org/obo/GO_0097282	immunoglobulin-mediated neutralization		immunoglobulin-mediated neutralization resulting from antibody binding to epitope
http://purl.obolibrary.org/obo/OBI_0001715	obsolete B cell epitope competitive binding assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A competitive inhibition of binding assay using a assay
http://purl.obolibrary.org/obo/OBI_0001716	B cell epitope specific complement-dependent cytotoxicity	http://purl.obolibrary.org/obo/GO_0097278	complement-dependent cytotoxicity		complement-dependent cytotoxicity resulting from antibody binding to epitope
http://purl.obolibrary.org/obo/OBI_0001717	B cell epitope specific antibody-dependent cellular cytotoxicity	http://purl.obolibrary.org/obo/GO_0001788	antibody-dependent cellular cytotoxicity		antibody-dependent cellular cytotoxicity resulting from antibody binding to epitope
http://purl.obolibrary.org/obo/OBI_0001718	assay measuring the on rate [kon] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001709	assay measuring a binding constant of a B cell epitope:antibody complex		A B cell epitope binding constant determination assay that measures the on rate.
http://purl.obolibrary.org/obo/OBI_0001719	assay measuring the association constant [KA] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001709	assay measuring a binding constant of a B cell epitope:antibody complex		A B cell epitope binding constant determination assay that measures the association constant KA.
http://purl.obolibrary.org/obo/OBI_0001720	B cell epitope specific immune complex formation	http://purl.obolibrary.org/obo/GO_0097281	immune complex formation		immune complex formation resulting from antibody binding to epitope
http://purl.obolibrary.org/obo/OBI_0001721	3D molecular structure determination assay of an antigen:antibody complex	http://purl.obolibrary.org/obo/OBI_0003127	B cell epitope assay		A 3D structure determination of bound molecular complex assay that characterizes the 3-dimensional structure of an antigen:antobody complex.
http://purl.obolibrary.org/obo/OBI_0001722	B cell epitope specific hypersensitivity	http://purl.obolibrary.org/obo/GO_0002524	hypersensitivity		hypersensitivity resulting from antibody binding to epitope
http://purl.obolibrary.org/obo/OBI_0001723	assay measuring the off rate [koff] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001709	assay measuring a binding constant of a B cell epitope:antibody complex		A B cell epitope binding constant determination assay that measures the off rate.
http://purl.obolibrary.org/obo/OBI_0001724	viral hemagglutination inhibition assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A viral hemagglutination inhibition assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001725	B cell epitope specific histamine secretion mediated by immunoglobulin	http://purl.obolibrary.org/obo/GO_0097280	histamine secretion mediated by immunoglobulin		histamine secretion mediated by immunoglobulin resulting from antibody binding to epitope
http://purl.obolibrary.org/obo/OBI_0001726	quenching assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A fluorescence quenching assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001727	RIA measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		A radio immuno assay that measures the dissociation constant [KD] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001728	ELISA measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		An enzyme-linked immunosorbent assay that measures the dissociation constant [KD] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001729	quenching assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		A fluorescence quenching assay that measures the dissociation constant [KD] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001730	surface plasmon resonance assay measuring the association constant [KA] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001719	assay measuring the association constant [KA] of a B cell epitope:antibody complex		A surface plasmon resonance binding assay that measures the association constant [KA] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001731	surface plasmon resonance assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		A surface plasmon resonance binding assay that measures the dissociation constant [KD] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001732	quenching assay measuring the association constant [KA] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001719	assay measuring the association constant [KA] of a B cell epitope:antibody complex		A fluorescence quenching assay that measures the association constant [KA] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001733	calorimetry assay measuring the association constant [KA] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001719	assay measuring the association constant [KA] of a B cell epitope:antibody complex		A calorimetric binding assay that measures the association constant [KA] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001734	calorimetry assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		A calorimetric binding assay that measures the dissociation constant [KD] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001735	ELISA measuring the association constant [KA] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001719	assay measuring the association constant [KA] of a B cell epitope:antibody complex		An enzyme-linked immunosorbent assay that measures the association constant [KA] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001736	RIA measuring the association constant [KA] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001719	assay measuring the association constant [KA] of a B cell epitope:antibody complex		A radio immuno assay that measures the association constant [KA] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001737	obsolete B cell epitope specific X-ray crystallography assay	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A X-ray crystallography assay measuring epitope specfic antibody binding event in angstroms
http://purl.obolibrary.org/obo/OBI_0001738	X-ray crystallography assay determining the 3D structure of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001721	3D molecular structure determination assay of an antigen:antibody complex		A X-ray crystallography 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a B cell epitope:antibody complex.
http://purl.obolibrary.org/obo/OBI_0001739	surface plasmon resonance assay measuring the off rate [koff] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001723	assay measuring the off rate [koff] of a B cell epitope:antibody complex		A surface plasmon resonance binding assay that measures the off rate [koff] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001740	quenching assay measuring the off rate [koff] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001723	assay measuring the off rate [koff] of a B cell epitope:antibody complex		A fluorescence quenching assay that measures the off rate [koff] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001741	surface plasmon resonance assay measuring the on rate [kon] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001718	assay measuring the on rate [kon] of a B cell epitope:antibody complex		A surface plasmon resonance binding assay that measures the on rate [kon] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001742	quenching assay measuring the on rate [kon] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001718	assay measuring the on rate [kon] of a B cell epitope:antibody complex		A fluorescence quenching assay that measures the on rate [kon] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001743	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001449	assay measuring epitope specific interleukin-1 beta production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-1 beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001744	intracellular cytokine staining assay measuring epitope specific interleukin-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001388	assay measuring epitope specific interleukin-1 alpha production by T cells		A flow cytometry assay that detects interleukin-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001745	ELISPOT assay measuring epitope specific interleukin-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001746	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001388	assay measuring epitope specific interleukin-1 alpha production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001747	cytometric bead array assay measuring epitope specific interleukin-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001748	ELISPOT assay measuring epitope specific interferon-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interferon-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001749	intracellular cytokine staining assay measuring epitope specific interferon-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001390	assay measuring epitope specific interferon-beta production by T cells		A flow cytometry assay that detects interferon-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001750	intracellular cytokine staining assay measuring epitope specific granulocyte colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001600	assay measuring epitope specific granulocyte colony stimulating factor production by T cells		A flow cytometry assay that detects granulocyte colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001751	ELISA measuring epitope specific interferon-beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001390	assay measuring epitope specific interferon-beta production by T cells		An enzyme-linked immunosorbent assay that detects interferon-beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001752	detection of specific nucleic acids with complementary probes assay measuring epitope specific granulocyte colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001600	assay measuring epitope specific granulocyte colony stimulating factor production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects granulocyte colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001753	ELISPOT assay measuring epitope specific granulocyte colony stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects granulocyte colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001754	cytometric bead array assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001756	ELISPOT assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects chemokine (C-X-C motif) ligand 9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001757	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells	http://purl.obolibrary.org/obo/OBI_0001459	assay measuring epitope specific chemokine (C-X-C motif) ligand 9 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-X-C motif) ligand 9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001758	ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects chemokine (C-C motif) ligand 4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001759	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells	http://purl.obolibrary.org/obo/OBI_0001776	assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-X-C motif) ligand 12 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001760	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells	http://purl.obolibrary.org/obo/OBI_0001779	assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-X-C motif) ligand 13 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001761	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells	http://purl.obolibrary.org/obo/OBI_0001778	assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-X-C motif) ligand 16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001762	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells	http://purl.obolibrary.org/obo/OBI_0001774	assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-C motif) ligand 21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001763	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells	http://purl.obolibrary.org/obo/OBI_0001777	assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-C motif) ligand 22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001764	cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects chemokine (C-C motif) ligand 4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001765	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells	http://purl.obolibrary.org/obo/OBI_0001345	assay measuring epitope specific chemokine (C-C motif) ligand 4 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-C motif) ligand 4 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001766	detection of specific nucleic acids with complementary probes assay measuring epitope specific vascular endothelial growth factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001570	assay measuring epitope specific vascular endothelial growth factor production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects vascular endothelial growth factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001767	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells	http://purl.obolibrary.org/obo/OBI_0001775	assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-C motif) ligand 19 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001768	intracellular cytokine staining assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells	http://purl.obolibrary.org/obo/OBI_0001276	assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells		A flow cytometry assay that detects chemokine (C-C motif) ligand 1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001769	specimen collector role	http://purl.obolibrary.org/obo/OBI_0000202	investigation agent role		An Investigation agent role borne by a person or organization which 
is realized in a specimen collection process.
http://purl.obolibrary.org/obo/OBI_0001770	intracellular cytokine staining assay measuring epitope specific vascular endothelial growth factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001570	assay measuring epitope specific vascular endothelial growth factor production by T cells		A flow cytometry assay that detects vascular endothelial growth factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001771	ELISPOT assay measuring epitope specific vascular endothelial growth factor production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects vascular endothelial growth factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001772	assay measuring epitope specific interleukin-17F production by T cells	http://purl.obolibrary.org/obo/OBI_0001295	assay measuring epitope specific interleukin-17 production by T cells		An assay of epitope specific interleukin-17 production by T cells that detects interleukin-17F production.
http://purl.obolibrary.org/obo/OBI_0001773	assay measuring epitope specific interleukin-17A production by T cells	http://purl.obolibrary.org/obo/OBI_0001295	assay measuring epitope specific interleukin-17 production by T cells		An assay of epitope specific interleukin-17 production by T cells that detects interleukin-17A production.
http://purl.obolibrary.org/obo/OBI_0001774	assay measuring epitope specific chemokine (C-C motif) ligand 21 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001775	assay measuring epitope specific chemokine (C-C motif) ligand 19 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 19 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001776	assay measuring epitope specific chemokine (C-X-C motif) ligand 12 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 12 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001777	assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-C motif) ligand 22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001778	assay measuring epitope specific chemokine (C-X-C motif) ligand 16 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001779	assay measuring epitope specific chemokine (C-X-C motif) ligand 13 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects chemokine (C-X-C motif) ligand 13 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001780	ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects macrophage inflammatory protein-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001781	cytometric bead array assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects macrophage inflammatory protein-1 gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001782	detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001456	assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects macrophage inflammatory protein-1 gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001783	intracellular cytokine staining assay measuring epitope specific monocyte chemotactic protein-1 production by T cells	http://purl.obolibrary.org/obo/OBI_0001465	assay measuring epitope specific monocyte chemotactic protein-1 production by T cells		A flow cytometry assay that detects monocyte chemotactic protein-1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001784	ELISPOT assay measuring epitope specific monocyte chemotactic protein-1 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects monocyte chemotactic protein-1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001785	intracellular cytokine staining assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001456	assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells		A flow cytometry assay that detects macrophage inflammatory protein-1 gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001786	ELISPOT assay measuring epitope specific macrophage inflammatory protein-1 gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects inflammatory protein-1 gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_0001787	cytometric bead array assay measuring epitope specific vascular endothelial growth factor production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects vascular endothelial growth factor production by T cells.
http://purl.obolibrary.org/obo/OBI_0001788	detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects tumor necrosis factor superfamily cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_0001789	intracellular cytokine staining assay measuring epitope specific RANTES production by T cells	http://purl.obolibrary.org/obo/OBI_0001232	assay measuring epitope specific RANTES production by T cells		A flow cytometry assay that detects RANTES production by T cells.
http://purl.obolibrary.org/obo/OBI_0001790	ELISPOT assay measuring epitope specific RANTES production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects RANTES production by T cells.
http://purl.obolibrary.org/obo/OBI_0001791	ELISPOT assay measuring epitope specific lymphotoxin A production by T cells	http://purl.obolibrary.org/obo/OBI_0001327	assay measuring epitope specific lymphotoxin A production by T cells		An enzyme-linked immunospot assay that detects lymphotoxin A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001792	detection of specific nucleic acids with complementary probes assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001333	assay measuring epitope specific macrophage inflammatory protein-1 alpha production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects macrophage inflammatory protein-1 alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0001793	cytometric bead array assay measuring epitope specific lymphotoxin A production by T cells	http://purl.obolibrary.org/obo/OBI_0001368	cytometric bead array assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A cytometric bead array assay that detects lymphotoxin A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001794	detection of specific nucleic acids with complementary probes assay measuring epitope specific lymphotoxin A production by T cells	http://purl.obolibrary.org/obo/OBI_0001788	detection of specific nucleic acids with complementary probes assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects lymphotoxin A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001795	ELISPOT assay measuring epitope specific IP-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects IP-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001796	intracellular cytokine staining assay measuring epitope specific IP-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0001308	assay measuring epitope specific IP-10 production by T cells		A flow cytometry assay that detects IP-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001797	ELISPOT assay measuring epitope specific interleukin-9 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001798	intracellular cytokine staining assay measuring epitope specific interleukin-9 production by T cells	http://purl.obolibrary.org/obo/OBI_0001253	assay measuring interleukin-9 production by T cells		A flow cytometry assay that detects interleukin-9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001799	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-9 production by T cells	http://purl.obolibrary.org/obo/OBI_0001253	assay measuring interleukin-9 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-9 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001800	ELISPOT assay measuring epitope specific interleukin-8 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-8 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001801	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-8 production by T cells	http://purl.obolibrary.org/obo/OBI_0001218	assay measuring epitope specific interleukin-8 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-8 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001802	ELISPOT assay measuring epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-3 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001803	ELISA measuring epitope specific interleukin-7 production by T cells	http://purl.obolibrary.org/obo/OBI_0001587	assay measuring epitope specific interleukin-7 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-7 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001804	ELISPOT assay measuring epitope specific interleukin-7 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-7 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001805	intracellular cytokine staining assay measuring epitope specific interleukin-7 production by T cells	http://purl.obolibrary.org/obo/OBI_0001587	assay measuring epitope specific interleukin-7 production by T cells		A flow cytometry assay that detects interleukin-7 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001806	intracellular cytokine staining assay measuring epitope specific interleukin-27 production by T cells	http://purl.obolibrary.org/obo/OBI_0001198	assay measuring epitope specific interleukin-27 production by T cells		A flow cytometry assay that detects interleukin-27 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001807	cytometric bead array assay measuring epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-3 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001808	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-3 production by T cells	http://purl.obolibrary.org/obo/OBI_0001406	assay measuring epitope specific interleukin-3 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-3 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001809	assay measuring epitope specific granzyme A release by T cells	http://purl.obolibrary.org/obo/OBI_0001269	assay measuring epitope specific cytotoxic T cell degranulation		A T cell epitope specific cytotoxic T cell degranulation assay that detects granzyme A release by T cells.
http://purl.obolibrary.org/obo/OBI_0001810	assay measuring epitope specific granulysin release by T cells	http://purl.obolibrary.org/obo/OBI_0001269	assay measuring epitope specific cytotoxic T cell degranulation		A T cell epitope specific cytotoxic T cell degranulation assay that detects granulysin release by T cells.
http://purl.obolibrary.org/obo/OBI_0001811	cytometric bead array assay measuring epitope specific interleukin-27 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-27 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001812	intracellular cytokine staining assay measuring epitope specific interleukin-23 production by T cells	http://purl.obolibrary.org/obo/OBI_0001363	assay measuring epitope specific interleukin-23 production by T cells		A flow cytometry assay that detects interleukin-23 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001813	ELISPOT assay measuring epitope specific interleukin-27 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-27 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001814	ELISA measuring epitope specific interleukin-27 production by T cells	http://purl.obolibrary.org/obo/OBI_0001198	assay measuring epitope specific interleukin-27 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-27 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001815	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-18 production by T cells	http://purl.obolibrary.org/obo/OBI_0001380	assay measuring epitope specific interleukin-18 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-18 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001816	epitope specific chemokine (C-X-C motif) ligand 13 production by T cells	http://purl.obolibrary.org/obo/GO_0097391	chemokine (C-X-C motif) ligand 13 production		A process of chemokine (C-X-C motif) ligand 13 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001817	ELISPOT assay measuring epitope specific interleukin-18 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-18 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001818	epitope specific chemokine (C-X-C motif) ligand 12 production by T cells	http://purl.obolibrary.org/obo/GO_0097390	chemokine (C-X-C motif) ligand 12 production		A process of chemokine (C-X-C motif) ligand 12 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001819	epitope specific chemokine (C-C motif) ligand 22 production by T cells	http://purl.obolibrary.org/obo/GO_0071924	chemokine (C-C motif) ligand 22 production		A process of chemokine (C-C motif) ligand 22 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001820	epitope specific chemokine (C-X-C motif) ligand 16 production by T cells	http://purl.obolibrary.org/obo/GO_0097392	chemokine (C-X-C motif) ligand 16 production		A process of chemokine (C-X-C motif) ligand 16 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001821	ELISPOT assay measuring epitope specific interleukin-22 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001822	ELISPOT assay measuring epitope specific interleukin-23 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-23 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001823	epitope specific chemokine (C-C motif) ligand 21 production by T cells	http://purl.obolibrary.org/obo/GO_0097389	chemokine (C-C motif) ligand 21 production		A process of chemokine (C-C motif) ligand 21 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001824	intracellular cytokine staining assay measuring epitope specific interleukin-18 production by T cells	http://purl.obolibrary.org/obo/OBI_0001380	assay measuring epitope specific interleukin-18 production by T cells		A flow cytometry assay that detects interleukin-18 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001825	epitope specific chemokine (C-C motif) ligand 19 production by T cells	http://purl.obolibrary.org/obo/GO_0097388	chemokine (C-C motif) ligand 19 production		A process of chemokine (C-C motif) ligand 19 production by T cells resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0001826	ELISPOT assay measuring epitope specific interleukin-21 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-21 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001827	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells	http://purl.obolibrary.org/obo/OBI_0001276	assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-C motif) ligand 1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001828	cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects chemokine (C-C motif) ligand 1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001829	ELISPOT assay measuring epitope specific chemokine (C-C motif) ligand 1 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects chemokine (C-C motif) ligand 1 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001830	ELISPOT assay measuring epitope specific interleukin-17F production by T cells	http://purl.obolibrary.org/obo/OBI_0001772	assay measuring epitope specific interleukin-17F production by T cells		An enzyme-linked immunospot assay that detects interleukin-17F production by T cells.
http://purl.obolibrary.org/obo/OBI_0001831	ELISA measuring epitope specific interleukin-17F production by T cells	http://purl.obolibrary.org/obo/OBI_1110162	ELISA measuring epitope specific interleukin-17 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-17F production by T cells.
http://purl.obolibrary.org/obo/OBI_0001832	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17F production by T cells	http://purl.obolibrary.org/obo/OBI_0001772	assay measuring epitope specific interleukin-17F production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-17F production by T cells.
http://purl.obolibrary.org/obo/OBI_0001833	ELISPOT assay measuring epitope specific interleukin-17A production by T cells	http://purl.obolibrary.org/obo/OBI_0001773	assay measuring epitope specific interleukin-17A production by T cells		An enzyme-linked immunospot assay that detects interleukin-17A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001834	drawing a conclusion	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which new information is inferred from existing information.
http://purl.obolibrary.org/obo/OBI_0001835	cytometric bead array assay measuring epitope specific interleukin-18 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-18 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001836	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/OBI_0001280	assay measuring epitope specific interleukin-16 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001837	ELISA measuring epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/OBI_0001280	assay measuring epitope specific interleukin-16 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001838	ELISPOT assay measuring epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001839	intracellular cytokine staining assay measuring epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/OBI_0001280	assay measuring epitope specific interleukin-16 production by T cells		A flow cytometry assay that detects interleukin-16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001840	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-17A production by T cells	http://purl.obolibrary.org/obo/OBI_0001773	assay measuring epitope specific interleukin-17A production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-17A production by T cells.
http://purl.obolibrary.org/obo/OBI_0001841	intracellular cytokine staining assay measuring epitope specific interleukin-1 beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001449	assay measuring epitope specific interleukin-1 beta production by T cells		A flow cytometry assay that detects interleukin-1 beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001842	ELISPOT assay measuring epitope specific interleukin-1 beta production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-1 beta production by T cells.
http://purl.obolibrary.org/obo/OBI_0001843	detection of specific nucleic acids with complementary probes measuring epitope specific interleukin-15 production by T cells	http://purl.obolibrary.org/obo/OBI_0001292	assay measuring epitope specific interleukin-15 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-15 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001844	ELISPOT assay measuring epitope specific interleukin-12 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-12 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001845	intracellular cytokine staining assay measuring epitope specific interleukin-15 production by T cells	http://purl.obolibrary.org/obo/OBI_0001292	assay measuring epitope specific interleukin-15 production by T cells		A flow cytometry assay that detects interleukin-15 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001846	ELISPOT assay measuring epitope specific interleukin-15 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-15 production by T cells.
http://purl.obolibrary.org/obo/OBI_0001851	transcription start site identification objective	http://purl.obolibrary.org/obo/OBI_0001331	transcription profiling identification objective		A transcription profiling identification objective that aims to characterize the transcription start sites of genes.
http://purl.obolibrary.org/obo/OBI_0001852	paired-end library preparation	http://purl.obolibrary.org/obo/OBI_0000711	library preparation		A library preparation that results in the creation of a library of the 5' and 3' ends of DNA or cDNA fragments using adaptors and endonucleases. The preparation may or may not include cloning process.
http://purl.obolibrary.org/obo/OBI_0001853	DNase I hypersensitive sites sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay		An assay that identifies the location of regulatory regions, based on the genome-wide sequencing of regions super sensitive to cleavage by DNase I.
http://purl.obolibrary.org/obo/OBI_0001854	protein and RNA interaction identification objective	http://purl.obolibrary.org/obo/OBI_0000113	sequence feature identification objective		A sequence feature identification objective that aims to characterize the interactions between protein and RNA.
http://purl.obolibrary.org/obo/OBI_0001865	assay array	http://purl.obolibrary.org/obo/OBI_0000968	device		A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface.
http://purl.obolibrary.org/obo/OBI_0001866	secondary cultured cell	http://purl.obolibrary.org/obo/CL_0000010	cultured cell		A cultured cell that has been passaged or derives from a cell that has been passaged in culture.
http://purl.obolibrary.org/obo/OBI_0001867	establishing cell line	http://purl.obolibrary.org/obo/OBI_0600036	establishing cell culture		a process whereby a new type of cell line is created, either through passaging of a primary cell culture to relative genetic stability and compositional homogeneity, or through some experimental modification of an existing cell line to produce a new line with novel characteristics  (e.g. immortalization or some other stable genetic modification, or selection of some defined subset).
http://purl.obolibrary.org/obo/OBI_0001869	Illumina BeadChip	http://purl.obolibrary.org/obo/OBI_0001865	assay array		An array that consists of 3-micron silica beads that self assemble in microwells on either of two materials: fiber optic bundles or planar silica slides.
http://purl.obolibrary.org/obo/OBI_0001870	Illumina methylation BeadChip	http://purl.obolibrary.org/obo/OBI_0001869	Illumina BeadChip		A BeadChip made for an analyte assay that generates information about DNA methylation.
http://purl.obolibrary.org/obo/OBI_0001871	LSRFortessa X-20	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A flow cytometer analyzer manifactured by Becton ans Dickinson. Can be configured with up to 5 lasers, 488nm, 532 or 561 nm, 640 nm, 405 nm, 355 nm for measuring up to 20 parameters simultaneously.
http://purl.obolibrary.org/obo/OBI_0001872	sequence assembly process	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation that assembles two or more individual sequence reads into contiguous sequences (i.e., contigs).
http://purl.obolibrary.org/obo/OBI_0001873	number of errors	http://purl.obolibrary.org/obo/OBI_0001933	value specification		a data item that is the number of times that a given process failed, as an integer
http://purl.obolibrary.org/obo/OBI_0001874	random access memory size	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		random access memory size is a scalar measurement datum which denotes the amount of physical memory know as random access memory present of a computer or required by a computational process or data transformation
http://purl.obolibrary.org/obo/OBI_0001876	cell culture	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A material entity comprised of cultured cells and the media in which they are being propagated or stored.
http://purl.obolibrary.org/obo/OBI_0001878	establishing primary cell culture	http://purl.obolibrary.org/obo/OBI_0600036	establishing cell culture		an establishing cell culture process whereby cells explanted directly from an organismal source or specimen, and placed in culture for maintenance or propagation as a primary cell culture
http://purl.obolibrary.org/obo/OBI_0001879	reagent	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A biological or chemical entity that bears a reagent role in virtue of it being intended for application in a scientific technique  to participate in (or have molecular parts that participate in) a chemical reaction that facilitates the generation of data about some distinct entity, or the generation of some distinct material specified output.
http://purl.obolibrary.org/obo/OBI_0001880	organization of specimen provider principal investigator	http://purl.obolibrary.org/obo/OBI_0000245	organization		An organization that is the affiliation of the principal investigator providing the specimens for the investigation
http://purl.obolibrary.org/obo/OBI_0001881	organization of Bioinformatics Resource Center contact person	http://purl.obolibrary.org/obo/OBI_0000245	organization		An organization that is the affiliation of the person who is contact representative of a Bioinformatics Resource Center
http://purl.obolibrary.org/obo/OBI_0001882	target material in specimen specification	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which specifies the type of material that will be assayed in an investigation.
http://purl.obolibrary.org/obo/OBI_0001883	Bioinformatics Resource Center contact person	http://purl.obolibrary.org/obo/NCBITaxon_9606	Homo sapiens		A person who is the contact representative of a Bioinformatics Resource Center
http://purl.obolibrary.org/obo/OBI_0001884	specimen-based scope of investigation specification	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which specifies the scope of an investigation based on the heterogeneity of organisms or type of material that are the specified input of specimen collection.
http://purl.obolibrary.org/obo/OBI_0001885	specimen repository organization	http://purl.obolibrary.org/obo/OBI_0000245	organization		An organization that provides a service to store and distribute specimens
http://purl.obolibrary.org/obo/OBI_0001887	email address of Bioinformatics Resource Center contact person	http://purl.obolibrary.org/obo/IAO_0000429	email address		An email address of the person who is contact representative of a Bioinformatics Resource Center
http://purl.obolibrary.org/obo/OBI_0001888	sequencing facility contact person	http://purl.obolibrary.org/obo/NCBITaxon_9606	Homo sapiens		A person who is the contact representative at the sequencing facility
http://purl.obolibrary.org/obo/OBI_0001889	specimen provider principal investigator	http://purl.obolibrary.org/obo/NCBITaxon_9606	Homo sapiens		A person who is a principal investigator and provides the specimen
http://purl.obolibrary.org/obo/OBI_0001890	email address of specimen collector	http://purl.obolibrary.org/obo/IAO_0000429	email address		An email address of the person collecting the specimen
http://purl.obolibrary.org/obo/OBI_0001891	sequencing facility organization	http://purl.obolibrary.org/obo/OBI_0002198	molecular analysis facility organization		An organization that provides sequence determination service
http://purl.obolibrary.org/obo/OBI_0001892	specification of data to be generated in an investigation	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification which indicates the type of data that will be generated and submitted to a database.
http://purl.obolibrary.org/obo/OBI_0001893	organization of specimen collector	http://purl.obolibrary.org/obo/OBI_0000245	organization		An organization that is the affiliation of the person collecting the specimen
http://purl.obolibrary.org/obo/OBI_0001894	email address of sequencing facility contact person	http://purl.obolibrary.org/obo/IAO_0000429	email address		An email address of the contact representative at the sequencing facility
http://purl.obolibrary.org/obo/OBI_0001895	specimen collector	http://purl.obolibrary.org/obo/NCBITaxon_9606	Homo sapiens		A person who collects the specimen
http://purl.obolibrary.org/obo/OBI_0001896	investigation assay specification	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which indicates the assay type used to obtain data.
http://purl.obolibrary.org/obo/OBI_0001897	organization of sequencing facility contact person	http://purl.obolibrary.org/obo/OBI_0000245	organization		An organization that is the affiliation of the contact representative at the sequencing facility
http://purl.obolibrary.org/obo/OBI_0001898	comment on investigation	http://purl.obolibrary.org/obo/IAO_0000300	textual entity		A textual entity that is about any of the aspects of an investigation worth noting
http://purl.obolibrary.org/obo/OBI_0001899	target capture specification	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification which specifies how the material enrichment procedure will influence the scale, or type of material that will be assayed in the specimen.
http://purl.obolibrary.org/obo/OBI_0001900	specimen identifier assigned by specimen repository	http://purl.obolibrary.org/obo/OBI_0001616	specimen identifier		A specimen identifier which is assigned by a specimen repository
http://purl.obolibrary.org/obo/OBI_0001901	specimen identifier assigned by sequencing facility	http://purl.obolibrary.org/obo/OBI_0001616	specimen identifier		A specimen identifier which is assigned by a sequencing facility
http://purl.obolibrary.org/obo/OBI_0001902	sample preparation for sequencing assay	http://purl.obolibrary.org/obo/OBI_0000073	sample preparation for assay		A sample preparation for assay that preparation of nucleic acids for a sequencing assay
http://purl.obolibrary.org/obo/OBI_0001903	email address of specimen provider principal investigator	http://purl.obolibrary.org/obo/IAO_0000429	email address		An email address of the principal investigator providing the specimens for the investigation
http://purl.obolibrary.org/obo/OBI_0001904	sequencing service	http://purl.obolibrary.org/obo/OBI_0001547	material analysis service		A service provides sequencing service which is the realization of some sequencing such as RNA and DNA sequencing in which the service provider role is realized.
http://purl.obolibrary.org/obo/OBI_0001906	cancer cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		An immortal cell line derived from a transformed cell that was part of a malignant tumor.
http://purl.obolibrary.org/obo/OBI_0001907	immortalizing cell line transformation	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation		a genetic transformation of a cell line cell with transgenic constructs intended to confer the capability for indefinite propagation in culture
http://purl.obolibrary.org/obo/OBI_0001909	conclusion based on data	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that is inferred from data.
http://purl.obolibrary.org/obo/OBI_0001910	primary cell culture	http://purl.obolibrary.org/obo/OBI_0001876	cell culture		A cell culture comprised of primary cultured cells and the media in which they are being actively propaged or quiescently stored.
http://purl.obolibrary.org/obo/OBI_0001911	cell line culture	http://purl.obolibrary.org/obo/OBI_0001876	cell culture		A cell culture comprised of cell line cells and the media in which they are being actively propagated or quiescently stored.
http://purl.obolibrary.org/obo/OBI_0001912	cell freezing medium	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A processed material that serves as a liquid vehicle for freezing cells for long term quiescent stroage, which contains chemicls needed to sustain cell viability across freeze-thaw cycles.
http://purl.obolibrary.org/obo/OBI_0001916	DNA replication identification objective	http://purl.obolibrary.org/obo/OBI_0000131	molecular feature identification objective		A molecular feature identification objective that aims to examine charateristics of DNA replication, such as replication time.
http://purl.obolibrary.org/obo/OBI_0001917	chromosome conformation identification objective	http://purl.obolibrary.org/obo/OBI_0000131	molecular feature identification objective		A molecular feature identification objective that aims to determine spatial organization of chromatin.
http://purl.obolibrary.org/obo/OBI_0001921	RNA-binding protein immunoprecipitation tiling array profiling assay	http://purl.obolibrary.org/obo/OBI_0001918	RNA-binding protein immunoprecipitation array profiling assay		An RNA-binding protein immunoprecipitation array profiling assay that combines immunoprecipitation of an RNA-binding protein and RNA tiling array to identify mRNAs associated with selected RNA binding proteins (RBPs).
http://purl.obolibrary.org/obo/OBI_0001923	protein sequencing by tandem mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay		A sequencing assay that detremines amino acid sequences of proteins using multiple rounds of mass spectrometry and molecule fragmentation.
http://purl.obolibrary.org/obo/OBI_0001929	mass value specification	http://purl.obolibrary.org/obo/OBI_0001931	scalar value specification		A value specification that specifies the mass of some thing.
http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that is specifies one category out of a fixed number of nominal categories
http://purl.obolibrary.org/obo/OBI_0001931	scalar value specification	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that consists of two parts: a numeral and a unit label
http://purl.obolibrary.org/obo/OBI_0001932	comparing prediction to measurement	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which predicted values for some thing are compared to measured values for that thing.
http://purl.obolibrary.org/obo/OBI_0001933	value specification	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that specifies a value within a classification scheme or on a quantitative scale.
http://purl.obolibrary.org/obo/OBI_0001934	predicted value	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		an information content entity that has been generated by a prediction process in which an estimate of a value of an entity is made which can be measured but without performing such a measurement. The value specification is intended to be close to the value a measurement process would produce modulo a prediction error.
http://purl.obolibrary.org/obo/OBI_0001935	predicted mass value	http://purl.obolibrary.org/obo/OBI_0001934	predicted value		A predicted value where the prediction specifies the mass of some thing.
http://purl.obolibrary.org/obo/OBI_0001936	molecular-labeled material	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a material entity that is the specified output of an addition of molecular label process that aims to label some molecular target to allow for its detection in a detection of molecular label assay
http://purl.obolibrary.org/obo/OBI_0001939	genome coverage	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the total number of bases in reads, divided by genome size, assumed to be the reference size (for instance of 3.10 Gb for human and 2.73 Gb for mouse) and refers to the percentage of the genome that is contained in the assembly based on size estimates; these are usually based on cytological techniques. Genome coverage of 90–95% is generally considered to be good, as most genomes contain a considerable fraction of repetitive regions that are difficult to sequence. So it is not a cause for concern if the genome coverage of an assembly is a bit less than 100%.
http://purl.obolibrary.org/obo/OBI_0001941	contig N50	http://purl.obolibrary.org/obo/OBI_0001940	N50		N50 statistic computed for the contigs produced by the assembly process. A contig N50 is calculated by first ordering every contig by length from longest to shortest. Next, starting from the longest contig, the lengths of each contig are summed, until this running sum equals one-half of the total length of all contigs in the assembly. The contig N50 of the assembly is the length of the shortest contig in this list.
http://purl.obolibrary.org/obo/OBI_0001943	software pipeline	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		A plan specification that specifies a chain encoded in software of processing elements (processes, threads, coroutines, etc.), arranged so that the output of each element is the input of the next. Usually some amount of buffering is provided between consecutive elements.
http://purl.obolibrary.org/obo/OBI_0001944	sequence annotation	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process that identifies and reports sequence features (e.g. protein coding regions) in sequence data.
http://purl.obolibrary.org/obo/OBI_0001945	scaffold N50	http://purl.obolibrary.org/obo/OBI_0001940	N50		N50 statistic computed for the scaffold produced by the assembly process. The method for computing the value is similar to that of contig N50 but uses scaffold information instead of contig information
http://purl.obolibrary.org/obo/OBI_0001947	sequence annotation provider	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A person or organization reporting the feature annotation results from the analysis of a macromolecular sequence.
http://purl.obolibrary.org/obo/OBI_0001948	sequence assembly name	http://purl.obolibrary.org/obo/IAO_0000300	textual entity		A textual entity that is used to denote a sequence assembly.
http://purl.obolibrary.org/obo/OBI_0001949	sequence annotation reporting role	http://purl.obolibrary.org/obo/OBI_0000068	reporting party role		A reporting party role that is realized by a person or organization who reports the feature annotation results from the analysis of a macromolecular sequence.
http://purl.obolibrary.org/obo/OBI_0001952	flash freezing	http://purl.obolibrary.org/obo/OBI_0001953	freezing		A freezing process by which material entities are quickly frozen by subjecting them to cryogenic temperatures, or in direct contact with Liquid nitrogen at -320.8F or -196°C.
http://purl.obolibrary.org/obo/OBI_0001953	freezing	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process with the objective to bring some material entity to a temperature below its freezing point.
http://purl.obolibrary.org/obo/OBI_0001955	competitive binding reference ligand role	http://purl.obolibrary.org/obo/OBI_0000064	positive reference substance role		A positive reference substance role that inheres in a material entity that is known to bind to a target entity, and that is realized in a competitive binding assay that has as specified input the target entity, an evaluant and the positive reference substance, where the binding of the evaluant to the target is measured based on the evaluant's ability to compete with the positive reference substance for binding to the target.
http://purl.obolibrary.org/obo/OBI_0001956	assay using chromatin immunoprecipitation	http://purl.obolibrary.org/obo/OBI_0001700	immunoprecipitation assay		An assay that produces data about protein-DNA interaction or DNA epigenetic modification using immunoprecipitation
http://purl.obolibrary.org/obo/OBI_0001957	hardware testing design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that aims to compare different types of hardware for performance, reproducibility, accuracy and precision.
http://purl.obolibrary.org/obo/OBI_0001958	systematic review study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design for identifying in the literature prior studies of a pre-determined phenomenon or set of related phenomena according to certain criteria, extracting findings from these studies, and summarizing these findings and/or attempting to draw new conclusions from them which were not justified by any of the individual, prior studies. Many systematic reviews also assess the quality of the studies so reviewed.
http://purl.obolibrary.org/obo/OBI_0001959	multiplexed nucleotide library sequencing	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A planned process which consists in running a set of samples as a pool on a sequencing instrument, while retaining the ability to associate individual results to each of the individual input samples through the use of a ligated oligonucleotide (the "multiplex identifier sequence"). This oligonucleotide is  introduced during the sequence library preparation, and is unique to and specific for all library fragments derived from each sample in a sample pool.
http://purl.obolibrary.org/obo/OBI_0001961	PCR program	http://purl.obolibrary.org/obo/IAO_0000104	plan specification		a PCR program is a plan specification which is executed during a polymerase chain reaction (PCR) by a thermocycler instrument that will iterate through the changes in temperature and duration of each of the annealing, denaturation, elongation steps for as many times as specified by the program.
http://purl.obolibrary.org/obo/OBI_0001962	target gene specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		is a directive information specifying a coding genomic region which is the focus of a planned process such as an assay, for instance in a environmental gene survey
http://purl.obolibrary.org/obo/OBI_0001963	target subfragment specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		is a directive information specifying a genomic region, possibly located in a coding genomic region, which is the focus of a planned process such as an assay, for instance in a environmental gene survey
http://purl.obolibrary.org/obo/OBI_0001965	decision analysis study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		a study design that has a decision analysis objective specification as part
http://purl.obolibrary.org/obo/OBI_0001966	sequence library data demultiplexing	http://purl.obolibrary.org/obo/OBI_0200187	sequence analysis data transformation		is a data transformation which uses sequence alignment and  'multiplex identifier sequence' information to separate all reads belonging to a given single sample following the sequencing of a multiplexed library
http://purl.obolibrary.org/obo/OBI_0001967	multiplexing sequence identifier	http://purl.obolibrary.org/obo/CHEBI_16991	deoxyribonucleic acid		A multiplexing sequence identifier is a nucleic acid sequence which is used in a ligation step of library preparation process to allow pooling of samples while maintaining ability to identify individual source material and creation of a multiplexed library
http://purl.obolibrary.org/obo/OBI_0001968	operational taxonomic unit matrix	http://purl.obolibrary.org/obo/IAO_0000027	data item		Operational Taxonomic Unit matrix  is a data item, organized as a table, where organismal taxonomic units, computed by sequence analysis and genetic distance calculation, are counted in a set of biological or environmental samples. The table is  used to appraise biodiversity of a population or community of living organism.
http://purl.obolibrary.org/obo/OBI_0001969	biodiversity assessment objective	http://purl.obolibrary.org/obo/OBI_0000015	biological feature identification objective		biodiversity assessment objective is an objective of a planned process aimed at producing data item whose interpretation should provide insight about variety of biological species found in a biological sample at macroscopic or microscopic level
http://purl.obolibrary.org/obo/OBI_0001976	hydrogen/deuterium exchange footprinting assay	http://purl.obolibrary.org/obo/OBI_0002162	footprinting assay		A footprinting assay that uses a chemical reaction whereby a covalently bonded hydrogen atom is replaced by a deuterium atom, or vice versa in order to gather information about the solvent accessibility of parts of a molecule and thus its tertiary structure.
http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that counts and/or measures characteristics of cells.
http://purl.obolibrary.org/obo/OBI_0001978	immunoblot assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that detects specific molecules in an input material by separating it using gel electrophoresis, transfering the separated molecules to a membrane, and staining them with_ antibodies specific to the analyte molecules.
http://purl.obolibrary.org/obo/OBI_0001979	fluorescence quenching binding assay	http://purl.obolibrary.org/obo/OBI_0001499	binding assay using fluorescence detection		A binding assay in which the proximity of two entities is monitored by measuring a fluorescent signal of one of the entities that gets reduced if the two entities are cliose to each other.
http://purl.obolibrary.org/obo/OBI_0001980	in vivo intervention experiment	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay in which the effect of a targeted process (the intervention) on an organism is tested.
http://purl.obolibrary.org/obo/OBI_0001981	disease exacerbation in vivo intervention experiment	http://purl.obolibrary.org/obo/OBI_0001980	in vivo intervention experiment		An in vivo intervention experiment that tests the ability of the intervention to increase the severity of a disease in the host.
http://purl.obolibrary.org/obo/OBI_0001982	protection from challenge in vivo intervention experiment	http://purl.obolibrary.org/obo/OBI_0001980	in vivo intervention experiment		An in vivo intervention experiment that tests the ability of the intervention to prevent occurrence of a disease in a host.
http://purl.obolibrary.org/obo/OBI_0001983	tolerance induction intervention experiment	http://purl.obolibrary.org/obo/OBI_0001980	in vivo intervention experiment		An in vivo intervention experiment that tests the ability of the intervention to decrease an immune response.
http://purl.obolibrary.org/obo/OBI_0001984	treatment intervention experiment	http://purl.obolibrary.org/obo/OBI_0001980	in vivo intervention experiment		An in vivo intervention experiment in which the ability of the intervention to reduce or cure the effects of a disease are tested.
http://purl.obolibrary.org/obo/OBI_0001985	microarray assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay where binding of the analyte to immobilized matrix is measured.
http://purl.obolibrary.org/obo/OBI_0001986	immunohistochemistry	http://purl.obolibrary.org/obo/OBI_0001632	immuno staining assay		An immunostaining assay to detect and potentially localize antigens within the cells of a tissue section.
http://purl.obolibrary.org/obo/OBI_0001987	assay measuring the association constant [KA] of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001553	assay measuring a binding constant of a MHC:ligand complex		A MHC binding constant determination assay measuring equilibrium association constant (KA).
http://purl.obolibrary.org/obo/OBI_0001988	assay measuring the dissociation constant [KD] of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001553	assay measuring a binding constant of a MHC:ligand complex		A MHC binding constant determination assay measuring equilibrium dissociation constant (KD).
http://purl.obolibrary.org/obo/OBI_0001989	radioactivity detection assay measuring equilibrium dissociation constant [KD] to determine competitive binding of a purified-MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001988	assay measuring the dissociation constant [KD] of a MHC:ligand complex		A radioactivity detection assay that measures equilibrium dissociation constant (KD) to detect the loss of binding of a known reference ligand to purified-MHC due to competition by the ligand under investigation.
http://purl.obolibrary.org/obo/OBI_0001990	assay measuring the half life of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001553	assay measuring a binding constant of a MHC:ligand complex		A MHC binding constant determination assay measuring half life of binding.
http://purl.obolibrary.org/obo/OBI_0001991	assay measuring the half maximal effective concentration [EC50] of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0003145	assay measuring quantitative binding of a MHC:ligand complex		A MHC binding constant determination assay measuring half maximal effective concentration (EC50).
http://purl.obolibrary.org/obo/OBI_0001992	assay measuring the half maximal inhibitory concentration [IC50] of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0003145	assay measuring quantitative binding of a MHC:ligand complex		A MHC binding constant determination assay measuring half maximal inhibitory concentration (IC50).
http://purl.obolibrary.org/obo/OBI_0001993	assay measuring the off rate measurement [koff] of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001553	assay measuring a binding constant of a MHC:ligand complex		A MHC binding constant determination assay measuring binding off rate measurement data item (koff).
http://purl.obolibrary.org/obo/OBI_0001994	assay measuring the MHC ligand binding on rate [kon] of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0001553	assay measuring a binding constant of a MHC:ligand complex		A MHC binding constant determination assay measuring binding on rate (kon).
http://purl.obolibrary.org/obo/OBI_0001995	chromatography assay measuring the association constant [KA] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001719	assay measuring the association constant [KA] of a B cell epitope:antibody complex		An analytical chromatography assay that measures the association constant [KA] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001996	chromatography assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		An analytical chromatography assay that measures the dissociation constant [KD] of an antigen binding with an antibody.
http://purl.obolibrary.org/obo/OBI_0001997	hydrogen/deuterium exchange footprinting assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0002449	footprinting assay measuring binding of a B cell epitope:antibody complex		A hydrogen/deuterium exchange footprinting assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001998	immunohistochemistry assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001986	immunohistochemistry		A immunohistochemistry assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0001999	3D molecular structure determination assay of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0003128	T cell epitope assay		A 3D structure determination of bound molecular complex assay that characterizes the 3-dimensional structure of a T cell epitope:MHC:TCR complex.
http://purl.obolibrary.org/obo/OBI_0002013	nCounter Human miRNA Expression array	http://purl.obolibrary.org/obo/OBI_0001865	assay array		A human array which is manufacutred by NanoString Technologies. Built upon color-coded molecular barcodes technology, the array profiles miRNA with increased specificity and sensitivty than microarrays.
http://purl.obolibrary.org/obo/OBI_0002020	epigenetic modification assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that identifies epigenetic modifications including histone modifications, open chromatin, and DNA methylation.
http://purl.obolibrary.org/obo/OBI_0002028	SAGE ditag library preparation	http://purl.obolibrary.org/obo/OBI_0000711	library preparation		A library preparation in which tags identifiying transcripts are created, ligated to form ditags, amplified, concatemerized and ligated into a vector to create a library.
http://purl.obolibrary.org/obo/OBI_0002036	array based nucleic acid structure mapping assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay which aims to provide information about the in vivo organization/structure of nucleic acids using chemical or enzymatic probes using a microarray.
http://purl.obolibrary.org/obo/OBI_0002037	micrococcal nuclease digestion followed by tiling array assay	http://purl.obolibrary.org/obo/OBI_0002036	array based nucleic acid structure mapping assay		An array based nucleic acid structure mapping assay that identifies nucleosome positions genome wide, by detection of regions protected by nucleosomes from digestion by micrococal nuclease using tiling array assays
http://purl.obolibrary.org/obo/OBI_0002047	enzyme-linked antibody	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A processed material that is comprised of an antibody that is covalently linked to an enzyme through bioconjugation. The enzyme can be used as a detection method when the enzyme's reaction produces a detectable signal, for example a color change when the substrate is added.
http://purl.obolibrary.org/obo/OBI_0002050	3D molecular structure determination assay of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0002075	MHC ligand assay		A 3D structure determination of bound molecular complex assay that characterizes the 3-dimensional structure of a MHC:ligand complex.
http://purl.obolibrary.org/obo/OBI_0002051	in vivo assay measuring B cell epitope specific protection from infectious challenge based on pathogen burden	http://purl.obolibrary.org/obo/OBI_0003465	in vivo assay measuring B cell epitope specific protection from pathogen challenge		An in vivo assay measuring B cell epitope specific protection from pathogen challenge using pathogen burden.
http://purl.obolibrary.org/obo/OBI_0002052	in vivo assay measuring B cell epitope specific protection after tumor burden challenge	http://purl.obolibrary.org/obo/OBI_0003466	in vivo assay measuring B cell epitope specific protection from tumor challenge		An in vivo assay measuring B cell epitope specific protection from tumor challenge using tumor burden.
http://purl.obolibrary.org/obo/OBI_0002053	microarray assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001985	microarray assay		A microarray assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0002054	NMR assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001708	assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex		A B cell epitope equilibrium dissociation constant (KD) determination assay that uses a nuclear magnetic resonance assay.
http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding	http://purl.obolibrary.org/obo/OBI_0003128	T cell epitope assay		A T cell epitope recognition assay that measures the immune response process resulting from the binding of a T cell receptor to epitope or the recongition of the epitope.
http://purl.obolibrary.org/obo/OBI_0002056	assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects production of chemokine (C-C motif) ligand 17 production by T cells.
http://purl.obolibrary.org/obo/OBI_0002057	assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects macrophage migration inhibitory factor (MIF) production by T cells.
http://purl.obolibrary.org/obo/OBI_0002058	assay measuring epitope specific oncostatin M production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects oncostatin M production by T cells.
http://purl.obolibrary.org/obo/OBI_0002059	assay measuring a binding constant of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0003147	assay measuring quantitative binding of an epitope:MHC:TCR complex		A T cell epitope recognition assay that quantitavely characterizes the binding of a TCR with a ligand by determining a binding constant.
http://purl.obolibrary.org/obo/OBI_0002060	detection of specific nucleic acids with complementary probes assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells	http://purl.obolibrary.org/obo/OBI_0002056	assay measuring epitope specific chemokine (C-C motif) ligand 17 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects chemokine (C-C motif) ligand 17 production by T cells.
http://purl.obolibrary.org/obo/OBI_0002061	cytometric bead array assay measuring epitope specific chemokine (C-C motif) ligand 22 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects chemokine (C-C motif) ligand 22 production by T cells.
http://purl.obolibrary.org/obo/OBI_0002062	in vitro assay measuring epitope specific T cell killing	http://purl.obolibrary.org/obo/OBI_1110130	assay measuring epitope specific T cell killing		An in vitro cell killing assay that measures the killing of antigen presenting cells (APC) by T cells whose TCR recognizes an epitope presented by the APC.
http://purl.obolibrary.org/obo/OBI_0002063	cytometric bead array assay measuring epitope specific granzyme A release by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects epitope specific granzyme A release by T cells.
http://purl.obolibrary.org/obo/OBI_0002064	detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme A release by T cells	http://purl.obolibrary.org/obo/OBI_0001809	assay measuring epitope specific granzyme A release by T cells		A detection of specific nucleic acids with complementary probes assay that detects epitope specific granzyme A release by T cells.
http://purl.obolibrary.org/obo/OBI_0002065	cytometric bead array assay measuring epitope specific granzyme B release by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects epitope specific granzyme B release by T cells.
http://purl.obolibrary.org/obo/OBI_0002066	detection of specific nucleic acids with complementary probes assay measuring epitope specific granzyme B release by T cells	http://purl.obolibrary.org/obo/OBI_0001436	assay measuring epitope specific granzyme B release by T cells		A detection of specific nucleic acids with complementary probes assay that detects epitope specific granzyme B release by T cells
http://purl.obolibrary.org/obo/OBI_0002067	cytometric bead array assay measuring epitope specific macrophage migration inhibitory factor (MIF) production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects macrophage migration inhibitory factor (MIF) production by T cells.
http://purl.obolibrary.org/obo/OBI_0002068	cytometric bead array assay measuring epitope specific oncostatin M production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects oncostatin M production by T cells.
http://purl.obolibrary.org/obo/OBI_0002069	ELISPOT assay measuring epitope specific perforin release by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects epitope specific perforin release by T cells.
http://purl.obolibrary.org/obo/OBI_0002070	in vivo assay measuring epitope specific proliferation of T cells	http://purl.obolibrary.org/obo/OBI_1110131	assay measuring epitope specific proliferation of T cells		A T cell epitope specific proliferation assay that is performed in vivo.
http://purl.obolibrary.org/obo/OBI_0002071	in vitro assay measuring epitope specific proliferation of T cells	http://purl.obolibrary.org/obo/OBI_1110131	assay measuring epitope specific proliferation of T cells		A T cell epitope specific proliferation assay that is performed on cells in vitro.
http://purl.obolibrary.org/obo/OBI_0002072	assay measuring qualitative binding of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_1110126	assay measuring binding of a MHC:ligand complex		An assay that detects the binding of a MHC molecule with a ligand, and produces a qualitative measurement of the binding as an output.
http://purl.obolibrary.org/obo/OBI_0002073	in vivo assay measuring T cell epitope specific protection from challenge	http://purl.obolibrary.org/obo/OBI_0001484	assay measuring T cell epitope specific in vivo activity		An efficacy of T cell epitope intervention experiment that uses a epitope protection experiment.
http://purl.obolibrary.org/obo/OBI_0002074	assay measuring T cell epitope specific suppression in vitro	http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding		T cell epitope dependent biological activity assay that detects suppression of an in vitro response.
http://purl.obolibrary.org/obo/OBI_0002075	MHC ligand assay	http://purl.obolibrary.org/obo/OBI_1110128	immune epitope assay		An immune epitope assay that characterizes the structrue of a MHC-ligand complex, or detects the processing and presentation of a ligand by an antigen presenting cell, or the binding of a ligand to an MHC molecule.
http://purl.obolibrary.org/obo/OBI_0002076	collection of specimens	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that has two or more specimens as its parts.
http://purl.obolibrary.org/obo/OBI_0002078	specimen set collection process	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process		A specimen collection process that generates multiple specimens from one source (e.g. one organism) during a time period which for the purpose of the study can be considered to be taken at the same sampling time.
http://purl.obolibrary.org/obo/OBI_0002080	human specimen set	http://purl.obolibrary.org/obo/OBI_0002079	specimens collected in one encounter		A specimen set that is collected from one person during a time period which for the purpose of the study can be considered to be taken at the same sampling time.
http://purl.obolibrary.org/obo/OBI_0002081	specimens collected longitudinally	http://purl.obolibrary.org/obo/OBI_0002076	collection of specimens		A collection of specimens that was derived from the same source material entity at different time points in order to observe changes in that entity.
http://purl.obolibrary.org/obo/OBI_0002087	containing a specimen function	http://purl.obolibrary.org/obo/OBI_0000370	contain function		A contain function that involves physical contact with a specimen. This function is typically performed in such a way that the specimen is usable for an investigation or assay.
http://purl.obolibrary.org/obo/OBI_0002088	specimen container	http://purl.obolibrary.org/obo/OBI_0000967	container		A container with the function of containing a specimen.
http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A container with an environmental control function.
http://purl.obolibrary.org/obo/OBI_0002095	specimen family creation	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A material processing that has as its input a specimen and as its output a collection of specimens.
http://purl.obolibrary.org/obo/OBI_0002096	carboxyfluorescein succinimidyl ester staining assay measuring epitope specific proliferation of T cells	http://purl.obolibrary.org/obo/OBI_0002106	carboxyfluorescein succinimidyl ester staining assay		A CFSE assay that detects T cell epitope specific proliferation in vitro.
http://purl.obolibrary.org/obo/OBI_0002097	assay measuring the dissociation constant [KD] of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0002059	assay measuring a binding constant of a T cell epitope:MHC:TCR complex		A T cell epitope binding constant determination assay that measures the dissociation constant KD.
http://purl.obolibrary.org/obo/OBI_0002098	assay measuring the on rate [kon] of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0002059	assay measuring a binding constant of a T cell epitope:MHC:TCR complex		A T cell epitope binding constant determination assay that measures the on rate.
http://purl.obolibrary.org/obo/OBI_0002099	assay measuring the off rate [koff] of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0002059	assay measuring a binding constant of a T cell epitope:MHC:TCR complex		A T cell epitope binding constant determination assay that measures the off rate.
http://purl.obolibrary.org/obo/OBI_0002100	assay measuring the association constant [KA] of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0002059	assay measuring a binding constant of a T cell epitope:MHC:TCR complex		A T cell epitope binding constant determination assay that measures the association constant KA.
http://purl.obolibrary.org/obo/OBI_0002101	small-angle scattering assay determining the 3D structure of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0002108	small-angle scattering 3D molecular structure determination assay		A small-angle scattering 3D molecular structure determination assay that characterizes the 3-dimensional molecular structure of a B cell epitope:antibody complex
http://purl.obolibrary.org/obo/OBI_0002102	bio-layer interferometry assay measuring the on rate [kon] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0002107	bio-layer interferometry assay		A bio-layer interferometry assay that measures the on rate of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0002103	bio-layer interferometry assay measuring the off rate [koff] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0002107	bio-layer interferometry assay		A bio-layer interferometry assay that measures the off rate of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0002104	bio-layer interferometry assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0002107	bio-layer interferometry assay		A bio-layer interferometry assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0002105	bio-layer interferometry assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0002107	bio-layer interferometry assay		A bio-layer interferometry assay that measures the dissociation constant [KD] of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0002119	microscopy assay	http://purl.obolibrary.org/obo/OBI_0000185	imaging assay		An imaging assay that utilizes a microscope to magnify features of the visualized material of interest that are not visible to naked eye.
http://purl.obolibrary.org/obo/OBI_0002500	amniotic fluid specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from amniotic fluid.
http://purl.obolibrary.org/obo/OBI_0002501	bile specimen	http://purl.obolibrary.org/obo/OBI_0002504	digestive system fluid or secretion specimen		A specimen that is derived from bile.
http://purl.obolibrary.org/obo/OBI_0002502	cerebrospinal fluid specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from cerbrospinal fluid.
http://purl.obolibrary.org/obo/OBI_0002505	milk specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from milk.
http://purl.obolibrary.org/obo/OBI_0002506	pericardial fluid specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from pericardial fluid.
http://purl.obolibrary.org/obo/OBI_0002507	saliva specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from saliva.
http://purl.obolibrary.org/obo/OBI_0002508	sputum specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from sputum.
http://purl.obolibrary.org/obo/OBI_0002509	sweat specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from sweat.
http://purl.obolibrary.org/obo/OBI_0002510	synovial fluid specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from synovial fluid.
http://purl.obolibrary.org/obo/OBI_0002512	bone marrow specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from bone marrow.
http://purl.obolibrary.org/obo/OBI_0002513	placenta specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from placenta.
http://purl.obolibrary.org/obo/OBI_0002514	peritoneal fluid specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from peritoneal fluid.
http://purl.obolibrary.org/obo/OBI_0002515	pleural fluid specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from pleural fluid.
http://purl.obolibrary.org/obo/OBI_0002516	brain specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from brain.
http://purl.obolibrary.org/obo/OBI_0002517	hair specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from hair.
http://purl.obolibrary.org/obo/OBI_0002518	prostate gland specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from prostate gland.
http://purl.obolibrary.org/obo/OBI_0002519	skeletal muscle tissue specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from skeletal muscle.
http://purl.obolibrary.org/obo/OBI_0002520	heart specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from heart.
http://purl.obolibrary.org/obo/OBI_0002522	adrenal gland specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from adrenal gland.
http://purl.obolibrary.org/obo/OBI_0002524	urinary bladder specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from urinary bladder.
http://purl.obolibrary.org/obo/OBI_0002525	tibial artery specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from tibial artery.
http://purl.obolibrary.org/obo/OBI_0002527	pancreas specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from pancreas.
http://purl.obolibrary.org/obo/OBI_0002528	stomach specimen	http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen		A specimen that is derived from stomach.
http://purl.obolibrary.org/obo/OBI_0002529	pituitary gland specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from pituitary gland.
http://purl.obolibrary.org/obo/OBI_0002530	adipose tissue specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from adipose tissue.
http://purl.obolibrary.org/obo/OBI_0002532	esophagus mucosa specimen	http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen		A specimen that is derived from esophagus mucosa.
http://purl.obolibrary.org/obo/OBI_0002533	colon specimen	http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen		A specimen that is derived from colon.
http://purl.obolibrary.org/obo/OBI_0002534	lung specimen	http://purl.obolibrary.org/obo/OBI_0002783	lower respiratory tract specimen		A specimen that is derived from lung.
http://purl.obolibrary.org/obo/OBI_0002537	thyroid gland specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from thyroid gland.
http://purl.obolibrary.org/obo/OBI_0002539	tibial nerve specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from tibial nerve.
http://purl.obolibrary.org/obo/OBI_0002540	coronary artery specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from coronary artery.
http://purl.obolibrary.org/obo/OBI_0002541	spleen specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from spleen.
http://purl.obolibrary.org/obo/OBI_0002542	aorta specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from aorta.
http://purl.obolibrary.org/obo/OBI_0005246	injection function	http://purl.obolibrary.org/obo/BFO_0000034	function		The function of a device realized when administering a substance in vivo, applied particularly to the forcible insertion of a liquid or gas by means of a syringe, pump, etc.
http://purl.obolibrary.org/obo/OBI_0100010	Epstein Barr virus transformed B cell	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A material entity which results from viral transformation process using EBV as transformation agent when applied to B-cell entity
http://purl.obolibrary.org/obo/OBI_0100014	chimera	http://purl.obolibrary.org/obo/OBI_0100026	organism		An organism which contains cells or tissues with a different genotype
http://purl.obolibrary.org/obo/OBI_0100015	obsolete_anatomical entity	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An anatomical entity is a material entity that is part of a multicellular organism, and which is large enough so that it forms an identifiable structure in the organism. Specifically, it excludes granular parts of the organism, such as atoms, molecules, cells, which can be removed from the organism without affecting it. It is defined as the union of 'multi-tissue structure', 'body substance' and 'portion of tissue'
http://purl.obolibrary.org/obo/OBI_0100017	blood serum specimen	http://purl.obolibrary.org/obo/OBI_0100016	blood plasma specimen		A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors.
http://purl.obolibrary.org/obo/OBI_0100026	organism	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that is an individual living system, such as animal, plant, bacteria or virus, that is capable of replicating or reproducing, growth and maintenance in the right environment. An organism may be unicellular or made up, like humans, of many billions of cells divided into specialized tissues and organs.
http://purl.obolibrary.org/obo/OBI_0100035	obsolete_immortal cell	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a cell derived from a multicellular organism that has the potential to replicate indefinitely
http://purl.obolibrary.org/obo/OBI_0100039	obsolete_fragment derived from protein	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A material entity which is derived from a  protein
http://purl.obolibrary.org/obo/OBI_0100051	specimen	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that is collected for potential use as an input upon which measurements or observations are performed.
http://purl.obolibrary.org/obo/OBI_0100055	obsolete_cell line cell	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A material entity that represents generations of a primary culture.
http://purl.obolibrary.org/obo/OBI_0100064	screening library	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a screening library is a collection of materials engineered to identify qualities of a subset of its members during a screening process?
http://purl.obolibrary.org/obo/OBI_0100065	synthetic peptide	http://purl.obolibrary.org/obo/CHEBI_16670	peptide		a synthetic peptide is an material entity which is artificially engineered and results from the synthesis of a chain of amino acids which may also be found in natural protein and be identical in sequence to a protein fragment
http://purl.obolibrary.org/obo/OBI_0100066	organ section	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A processed material which derives from an organ and results from a process of dissection or histological sample preparation a portion(formerly an organ section is portion of an organ removed from the context of the organ)
http://purl.obolibrary.org/obo/OBI_0100069	obsolete_polymer	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
http://purl.obolibrary.org/obo/OBI_0200001	geometric mean calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A data transformation in which the mean is calculated by taking the nth root of the product of all of the observations in a data (n being the number of all observations).
http://purl.obolibrary.org/obo/OBI_0200002	logistic-log curve fitting	http://purl.obolibrary.org/obo/OBI_0200072	curve fitting data transformation		A logistic-log curve fitting is a curve fitting where a curve of the form y=d+((a-d)/(1+(x/c)^b)) is obtained, where a, b, c, and d are determined so to optimize its fit to the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n).
http://purl.obolibrary.org/obo/OBI_0200003	logit-log curve fitting	http://purl.obolibrary.org/obo/OBI_0200072	curve fitting data transformation		A logit-log curve fitting is a curve fitting where first the limits y_0 an y_infty of y when x->0 and x->infinity, respectively, are estimated from the input data points (x_1, y_1), (x_2,y_2), ..., (x_n, y_n). Then a curve with equation log((y-y_0)/(y_infty-y))=a+b log(x) is obtained, where a and b are determined to optimize its fit to the input data points.
http://purl.obolibrary.org/obo/OBI_0200004	log-log curve fitting	http://purl.obolibrary.org/obo/OBI_0200072	curve fitting data transformation		A log-log curve fitting is a curve fitting where first a logarithmic transformation is applied both to the x and the y coordinates of the input data points (x_1, y_1), (x_2, y_2), ..., (x_n, y_n), and then coefficients a and b are determined to optimize the fit of log(y)=a+b*log(x) to these input data points.
http://purl.obolibrary.org/obo/OBI_0200005	feature extraction objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A feature extraction objective is a data transformation objective where the aim of the data transformation is to generate quantified values from a scanned image.
http://purl.obolibrary.org/obo/OBI_0200006	biexponential transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A biexponential transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation B(y)-x=0, where B denotes a b transformation.
http://purl.obolibrary.org/obo/OBI_0200007	box-cox transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A box-cox transformation is a data transformation according to the methods of Box and Cox as described in the article Box, G. E. P. and Cox, D.R. (1964) An analysis of transformations. Journal of Royal Statistical Society, Series B, vol. 26, pp. 211-246.
http://purl.obolibrary.org/obo/OBI_0200008	hyperlog transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A hyperlog transformation ia a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation EH(y)-x=0, where EH denotes an eh transformation.
http://purl.obolibrary.org/obo/OBI_0200010	loess scale group transformation one-channel	http://purl.obolibrary.org/obo/OBI_0200025	loess scale group transformation		A loess scale group transformation one-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation one-channel, to render the M group variances similar.
http://purl.obolibrary.org/obo/OBI_0200011	logical transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A logical transformation is a data transformation that, for each (one dimensional) real number input x, outputs an approximation (found, e.g. with the Newton's method) to a solution y of the equation S(y)-x=0, where S denotes an s transformation.
http://purl.obolibrary.org/obo/OBI_0200012	loess scale group transformation two-channel	http://purl.obolibrary.org/obo/OBI_0200025	loess scale group transformation		A loess scale group transformation two-channel is a loess scale group transformation consisting in the application of a scale adjustment following a loess group transformation two-channel, to render the M group variances similar.
http://purl.obolibrary.org/obo/OBI_0200013	loess global transformation one-channel	http://purl.obolibrary.org/obo/OBI_0200023	loess global transformation		A loess global transformation one-channel is a loess global transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.
http://purl.obolibrary.org/obo/OBI_0200014	split-scale transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A split-scale transformation is a data transformation which is an application of a function f described as follows to a (one dimensional) real number input. f(x)=a*x+b if x=for x>t; where log denotes a logarithmic transformation and a, b, c, d, r, t are real constants, with a, c, d, r, t positive, chosen so that f is continuous with a continuous derivative at the transition point t.
http://purl.obolibrary.org/obo/OBI_0200015	loess global transformation two-channel	http://purl.obolibrary.org/obo/OBI_0200023	loess global transformation		A loess global transformation two-channel is a loess global transformation in the special case where the input the result of an MA transformation applied to intensities from the two channels of a two-channel assay.
http://purl.obolibrary.org/obo/OBI_0200016	sine transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A sine transformation is a data transformation which consists in applying the sine function to a (one dimensional) real number input. The sine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Sine.html.
http://purl.obolibrary.org/obo/OBI_0200017	cosine transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A cosine transformation is a data transformation which consists in applying the cosine function to a (one dimensional) real number input. The cosine function is one of the basic trigonometric functions and a definition is provided, e.g., at http://mathworld.wolfram.com/Cosine.html.
http://purl.obolibrary.org/obo/OBI_0200018	loess group transformation one-channel	http://purl.obolibrary.org/obo/OBI_0200024	loess group transformation		A loess group transformation one-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from two related one-channel assays.
http://purl.obolibrary.org/obo/OBI_0200019	loess group transformation two-channel	http://purl.obolibrary.org/obo/OBI_0200024	loess group transformation		A loess group transformation two-channel is a loess group transformation in the special case where the input is the result of an MA transformation applied to intensities from the two channels of a two-channel assay.
http://purl.obolibrary.org/obo/OBI_0200020	homogeneous polynomial transformation	http://purl.obolibrary.org/obo/OBI_0200093	polynomial transformation		A homogeneous polynomial transformation is a polynomial transformation where all the term of the polynomial have the same degree.
http://purl.obolibrary.org/obo/OBI_0200021	linlog transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A linlog transformation is a data transformation, described in PMID 16646782, whose input is a matrix [y_ik] and whose output is a matrix obtained by applying formula (9) of this paper, where values below an appropriately determined threshold (dependent on the row i) are transformed via a polynomial of degree 1, and values above this threshold are transformed via a logarithm.
http://purl.obolibrary.org/obo/OBI_0200023	loess global transformation	http://purl.obolibrary.org/obo/OBI_0200071	loess transformation		A loess global transformation is a loess transformation where only one loess fitting is performed, utilizing one subset of (or possibly all of) the data points in the input so that there is only one resulting loess curve y=f(x) which is used for the transformation.
http://purl.obolibrary.org/obo/OBI_0200024	loess group transformation	http://purl.obolibrary.org/obo/OBI_0200071	loess transformation		A loess group transformation is a loess transformation where the input is partitioned into groups and for each group a loess fitting is performed, utilizing a subset of (or possibly all of) the data points in that group. Thus, a collection of loess curves y=f_i(x) is generated, one per group. Each (x, y) in the input is transformed into (x, y-f_i(x)), where f_i(x) is the curve corresponding to the group to which that data point belongs.
http://purl.obolibrary.org/obo/OBI_0200025	loess scale group transformation	http://purl.obolibrary.org/obo/OBI_0200185	scaling data transformation		A loess scale group transformation is a data transformation consisting in the application of a scale adjustment following a loess group transformation, to render the group variances for the second variable (y) similar.  Has objective scaling.
http://purl.obolibrary.org/obo/OBI_0200026	total intensity transformation single	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A total intensity transformation single is a data transformation that takes as input an n-dimensional (real) vector and multiplies each component of this vector by a coefficient, where the coefficient is obtained by taking the sum of the input components or of a subset of these, multiplied by a constant of choice.
http://purl.obolibrary.org/obo/OBI_0200027	total intensity transformation paired	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A total intensity transformation paired is a data transformation that takes as input two n-dimensional (real) vectors and multiplies each component of the first vector by a coefficient, where the coefficient is obtained by taking the ratio of the sum of the second input components or of a subset of these by the sum of the first input components or of a subset of these (the same subset is used for the two vectors).
http://purl.obolibrary.org/obo/OBI_0200028	quantile transformation	http://purl.obolibrary.org/obo/OBI_0200181	center calculation data transformation		A quantile transformation is a data transformation that takes as input a collection of data sets, where each can be thought as an n-dimensional (real) vector, and which transforms each data set so that the resulting output data sets have equal quantiles.
http://purl.obolibrary.org/obo/OBI_0200031	differential expression analysis objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A differential expression analysis objective is a data transformation objective whose input consists of expression levels of entities (such as transcripts or proteins), or of sets of such expression levels, under two or more conditions and whose output reflects which of these are likely to have different expression across such conditions.
http://purl.obolibrary.org/obo/OBI_0200032	K-fold cross validation method	http://purl.obolibrary.org/obo/OBI_0000792	statistical model validation		K-fold cross-validation randomly partitions the original sample into K subsamples. Of the K subsamples, a single subsample is retained as the validation data for testing the model, and the remaining K - 1 subsamples are used as training data. The cross-validation process is then repeated K times (the folds), with each of the K subsamples used exactly once as the validation data. The K results from the folds then can be averaged (or otherwise combined) to produce a single estimation. The advantage of this method over repeated random sub-sampling is that all observations are used for both training and validation, and each observation is used for validation exactly once. 10-fold cross-validation is commonly used
http://purl.obolibrary.org/obo/OBI_0200033	leave one out cross validation method	http://purl.obolibrary.org/obo/OBI_0000792	statistical model validation		is a data transformation :  leave-one-out cross-validation (LOOCV) involves using a single observation from the original sample as the validation data, and the remaining observations as the training data. This is repeated such that each observation in the sample is used once as the validation data
http://purl.obolibrary.org/obo/OBI_0200035	boostrapping	http://purl.obolibrary.org/obo/OBI_0000792	statistical model validation		Bootstrapping is a statistical method for estimating the sampling distribution of a statistic by sampling with replacement from the original data, most often with the purpose of deriving robust estimates of standard errors and confidence intervals of a population parameter like a mean, median, proportion, odds ratio, correlation coefficient or regression coefficient
http://purl.obolibrary.org/obo/OBI_0200036	Benjamini and Hochberg false discovery rate correction method	http://purl.obolibrary.org/obo/OBI_0200163	false discovery rate correction method		A data transformation process in which the Benjamini and Hochberg method sequential p-value procedure  is applied with the aim of correcting false discovery rate
http://purl.obolibrary.org/obo/OBI_0200037	pareto scaling	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A pareto scaling is a data transformation that divides all measurements of a variable by the square root of the standard deviation of that variable.
http://purl.obolibrary.org/obo/OBI_0200040	modular decomposition	http://purl.obolibrary.org/obo/OBI_0200080	network analysis		Molecular decomposition is the partition of a network into distinct subgraphs for the purpose of identifying functional clusters. The network data is run through any of several existing algorithms designed to partition a network into distinct subgraphs for the purpose of isolating groups of functionally linked biological elements such as proteins.
http://purl.obolibrary.org/obo/OBI_0200041	k-means clustering	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		A k-means clustering is a data transformation which achieves a class discovery or partitioning objective, which takes as input a collection of objects (represented as points in multidimensional space) and which partitions them into a specified number k of clusters. The algorithm attempts to find the centers of natural clusters in the data. The most common form of the algorithm starts by partitioning the input points into k initial sets, either at random or using some heuristic data. It then calculates the mean point, or centroid, of each set. It constructs a new partition by associating each point with the closest centroid. Then the centroids are recalculated for the new clusters, and the algorithm repeated by alternate applications of these two steps until convergence, which is obtained when the points no longer switch clusters (or alternatively centroids are no longer changed).
http://purl.obolibrary.org/obo/OBI_0200042	hierarchical clustering	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		A hierarchical clustering is a data transformation which achieves a class discovery objective, which takes as input data item and builds a hierarchy of clusters. The traditional representation of this hierarchy is a tree (visualized by a dendrogram), with the individual input objects at one end (leaves) and a single cluster containing every object at the other (root).
http://purl.obolibrary.org/obo/OBI_0200043	average linkage hierarchical clustering	http://purl.obolibrary.org/obo/OBI_0200154	agglomerative hierarchical clustering		An average linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the average distance between objects from the first cluster and objects from the second cluster.
http://purl.obolibrary.org/obo/OBI_0200044	complete linkage hierarchical clustering	http://purl.obolibrary.org/obo/OBI_0200154	agglomerative hierarchical clustering		an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the maximum distance between objects from the first cluster and objects from the second cluster.
http://purl.obolibrary.org/obo/OBI_0200045	single linkage hierarchical clustering	http://purl.obolibrary.org/obo/OBI_0200154	agglomerative hierarchical clustering		A single linkage hierarchical clustering is an agglomerative hierarchical clustering which generates successive clusters based on a distance measure, where the distance between two clusters is calculated as the minimum distance between objects from the first cluster and objects from the second cluster.
http://purl.obolibrary.org/obo/OBI_0200049	Benjamini and Yekutieli false discovery rate correction method	http://purl.obolibrary.org/obo/OBI_0200163	false discovery rate correction method		A data transformation in which the Benjamini and Yekutieli method is applied with the aim of correcting false discovery rate
http://purl.obolibrary.org/obo/OBI_0200052	probabilistic algorithm	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A probabilistic algorithm is one which involves an element of probability or randomness in the transformation of the data.
http://purl.obolibrary.org/obo/OBI_0200053	expectation maximization	http://purl.obolibrary.org/obo/OBI_0200052	probabilistic algorithm		EM is a probabilistic algorithm used to estimate the maximum likelihood of parameters from existing data where the model involves unobserved latent variables. The input to this method is the data model for which the estimation is performed over and the output is an approximated probability function.
http://purl.obolibrary.org/obo/OBI_0200054	global modularity calculation	http://purl.obolibrary.org/obo/OBI_0200147	network graph quality calculation		A network graph quality calculation in which an input data set of subgraph modules and their in-degree and out-degree qualities is used to calculate the average modularity of subgraphs within the network.
http://purl.obolibrary.org/obo/OBI_0200055	dye swap merge	http://purl.obolibrary.org/obo/OBI_0200057	replicate analysis		A dye swap merge is a replicate analysis which takes as input data from paired two-channel microarray assays where the sample labeled with one dye in the first assay is labeled with the other dye in the second assay and vice versa. The output for each reporter is obtained by combining its (raw or possibly pre-processed) M values in the two assays, where the M value in an assay is defined as the difference of the log intensities in the two channels. This can be used as a normalization step, when appropriate assumptions are met.
http://purl.obolibrary.org/obo/OBI_0200056	moving average	http://purl.obolibrary.org/obo/OBI_0200170	averaging data transformation		A moving average is a data transformation in which center calculations, usually mean calculations, are performed on values within a sliding window across the input data set.
http://purl.obolibrary.org/obo/OBI_0200057	replicate analysis	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A replicate analysis is a data transformation in which data from replicates are combined, e.g. through descriptive statistics calculations, and the results might be utilized for a variety of purposes, like assessing reproducibility, identifying outliers, normalizing, etc.
http://purl.obolibrary.org/obo/OBI_0200058	b cell epitope prediction	http://purl.obolibrary.org/obo/OBI_0200187	sequence analysis data transformation		A B cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a B Cell Epitope.
http://purl.obolibrary.org/obo/OBI_0200059	mhc binding prediction	http://purl.obolibrary.org/obo/OBI_0200187	sequence analysis data transformation		An MHC binding prediction takes an input of a biomaterial sequence and through an analysis of this sequence, produces as output a prediction of the likelihood that the biomaterial will bind to an MHC molecule.
http://purl.obolibrary.org/obo/OBI_0200060	t cell epitope prediction	http://purl.obolibrary.org/obo/OBI_0200187	sequence analysis data transformation		A T cell epitope prediction takes as input an antigen sequence, and through an analysis of this sequence, produces as output a prediction of the likelihood the biomaterial is a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0200061	data imputation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Imputation is a means of filling in missing data values from a predictive distribution of the missing values.  The predictive distribution can be created either based on a formal statistical model (i,e, a multivariate normal distribution) or an algorithm.
http://purl.obolibrary.org/obo/OBI_0200062	continuum mass spectrum analysis	http://purl.obolibrary.org/obo/OBI_0200085	mass spectrometry analysis		A continuum mass spectrum is a data transformation that contains the full profile of the detected signals for a given ion.
http://purl.obolibrary.org/obo/OBI_0200063	characteristic path length calculation	http://purl.obolibrary.org/obo/OBI_0200085	mass spectrometry analysis		Quantifying subgraph navigability based on shortest-path length averaged over all pairs of subgraph vertices
http://purl.obolibrary.org/obo/OBI_0200066	Holm-Bonferroni family-wise error rate correction method	http://purl.obolibrary.org/obo/OBI_0200073	family wise error rate correction method		a data transformation that performs more than one hypothesis test simultaneously, a closed-test procedure, that  controls the familywise error rate for all the k hypotheses at level α in the strong sense. Objective: multiple testing correction
http://purl.obolibrary.org/obo/OBI_0200070	edge weighting	http://purl.obolibrary.org/obo/OBI_0200080	network analysis		Edge weighting is the substitution or transformation of edge length using numerical data.  Data input include a symmetric adjacency matrix for a network and a second data set, for example a list of interactor pairs and a confidence score associated with the experimental detection of each pair's interaction.  Each element in the adjacency matrix is transformed or replaced with the corresponding number in the second data set.  Output data are a modified adjacency matrix reflecting the transformed state of the network.
http://purl.obolibrary.org/obo/OBI_0200071	loess transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A loess transformation is a data transformation that takes as input a collection of real number pairs (x, y) and, after performing (one or more) loess fittings, utilizes the resulting curves to transform each (x, y) in the input into (x, y-f(x)) where f(x) is one of the fitted curves.
http://purl.obolibrary.org/obo/OBI_0200072	curve fitting data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A curve fitting is a data transformation that has objective curve fitting and that consists of finding a curve which matches a series of data points and possibly other constraints.
http://purl.obolibrary.org/obo/OBI_0200074	submatrix extraction	http://purl.obolibrary.org/obo/OBI_0200050	dimensionality reduction		A submatrix extraction is a projection whose input is a matrix and whose output is a matrix obtained by selecting certain rows and columns from the input. (Note that, if one represents the input matrix as a vector obtained by concatenating its rows, then extracting a submatrix is equivalent to projecting this vector into that composed by the entries belonging to the rows and columns of interest from the input matrix.)
http://purl.obolibrary.org/obo/OBI_0200075	row submatrix extraction	http://purl.obolibrary.org/obo/OBI_0200074	submatrix extraction		A row submatrix extraction is a submatrix extraction where all the columns of the input matrix are retained and selection only occurs on the rows.
http://purl.obolibrary.org/obo/OBI_0200076	column submatrix extraction	http://purl.obolibrary.org/obo/OBI_0200074	submatrix extraction		A column submatrix extraction is a submatrix extraction where all the rows of the input matrix are retained and selection only occurs on the columns.
http://purl.obolibrary.org/obo/OBI_0200077	gating	http://purl.obolibrary.org/obo/OBI_0200182	data vector reduction data transformation		Gating is a property-based vector selection with the objective of partitioning a data vector set into vector subsets based on dimension values of individual vectors (events), in which vectors represent individual physical particles (often cells) of a sample and dimension values represent light intensity qualities as measured by flow cytometry.
http://purl.obolibrary.org/obo/OBI_0200078	descriptive statistical calculation objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A descriptive statistical calculation objective is a data transformation objective which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.
http://purl.obolibrary.org/obo/OBI_0200079	arithmetic mean calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		An arithmetic mean calculation is a descriptive statistics calculation in which the mean is calculated by taking the sum of all of the observations in a data set divided by the total number of observations. It gives a measure of the 'center of gravity' for the data set. It is also known as the first moment.
http://purl.obolibrary.org/obo/OBI_0200081	sequence analysis objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A sequence analysis objective is a data transformation objective which aims to analyse some ordered biological data for sequential patterns.
http://purl.obolibrary.org/obo/OBI_0200085	mass spectrometry analysis	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation which has the objective of spectrum analysis.
http://purl.obolibrary.org/obo/OBI_0200086	spread calculation data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A spread calculation is a data transformation that has objective spread calculation.
http://purl.obolibrary.org/obo/OBI_0200088	Kaplan Meier	http://purl.obolibrary.org/obo/OBI_0200194	survival analysis data transformation		a nonparametric (actuarial) data transformation technique for estimating time-related events. It is a univariate analysis that estimates the probability of the proportion of subjects in remission at a particular time, starting from the initiation of active date (time zero), and takes into account those lost to follow-up or not yet in remission at end of study (censored)
http://purl.obolibrary.org/obo/OBI_0200093	polynomial transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A polynomial transformation is a data transformation that is obtained through a polynomial, where a polynomial is a mathematical expression involving a sum of powers in one or more variables multiplied by coefficients (e.g. see http://mathworld.wolfram.com/Polynomial.html). The number of variables and the degree are properties of a polynomial. The degree of a polynomial is the highest power of its terms, where the terms of a polynomial are the individual summands with the coefficients omitted.
http://purl.obolibrary.org/obo/OBI_0200094	logarithmic transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A logarithmic transformation is a data transformation consisting in the application of the logarithm function with a given base a (where a>0 and a is not equal to 1) to a (one dimensional) positive real number input. The logarithm function with base a can be defined as the inverse of the exponential function with the same base. See e.g. http://en.wikipedia.org/wiki/Logarithm.
http://purl.obolibrary.org/obo/OBI_0200095	exponential transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		An exponential transformation is a data transformation consisting in the application of the exponential function with a given base a (where a>0 and a is typically not equal to 1) to a (one dimensional) real number input. For alternative definitions and properties of this function see, e.g., http://en.wikipedia.org/wiki/Exponential_function and http://en.wikipedia.org/wiki/Characterizations_of_the_exponential_function.
http://purl.obolibrary.org/obo/OBI_0200097	non-negative matrix factorization	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Non negative matrix factorization is a data transformation in which factorises a matrix and which forces that all elements must be equal to or greater than zero.
http://purl.obolibrary.org/obo/OBI_0200099	discriminant function analysis	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		Discriminant function analysis is a form of discriminant analysis used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.
http://purl.obolibrary.org/obo/OBI_0200101	linear discriminant functional analysis	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		Linear discriminant functional analysis (LDFA) is a multivariate technique used in special applications where there are several intact groups (random assignment may be impossible) and they have been measured on several independent measures. Thus, you will want to describe how these groups differ on the basis of these measures. In this case, classification and prediction is the main objective.
http://purl.obolibrary.org/obo/OBI_0200102	regression analysis method	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Regression analysis is a descriptive statistics technique that examines the relation of a dependent variable (response variable) to specified independent variables (explanatory variables). Regression analysis can be used as a descriptive method of data analysis (such as curve fitting) without relying on any assumptions about underlying processes generating the data.
http://purl.obolibrary.org/obo/OBI_0200103	multiple linear regression analysis	http://purl.obolibrary.org/obo/OBI_0200102	regression analysis method		multiple linear regression is a regression method that models the relationship between a dependent variable Y, independent variables Xi, i = 1, ..., p, and a random term epsilon. The model can be written as
    Y = \beta_0 + \beta_1 X_1 + \beta_2 X_2 + \cdots +\beta_p X_p + \varepsilon
where \beta_0 =  0 is the intercept ("constant" term), the \beta_i s  are the respective parameters of independent variables, and p is the number of parameters to be estimated in the linear regression.
http://purl.obolibrary.org/obo/OBI_0200104	principal component regression	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		The Principal Component Regression method is a regression analysis method that combines the Principal Component Analysis (PCA)spectral decomposition with an Inverse Least Squares (ILS) regression method to create a quantitative model for complex samples. Unlike quantitation methods based directly on Beer's Law which attempt to calculate the absorbtivity coefficients for the constituents of interest from a direct regression of the constituent concentrations onto the spectroscopic responses, the PCR method regresses the concentrations on the PCA scores.
http://purl.obolibrary.org/obo/OBI_0200106	discriminant analysis	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Discriminant function analysis is used to determine which variables discriminate between two or more naturally occurring groups. Analysis is used to determine which variable(s) are the best predictors of a particular outcome.
http://purl.obolibrary.org/obo/OBI_0200108	eh transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		An eh transformation is a data transformation obtained by applying the function EH described in what follows to a (one dimensional) real number input. EH(x)=exp(x*d/r)+b*(d/r)*x-1, if x>=0, and EH(x)=-exp(-x*d/r)+b*(d/r)*x+1, otherwise. Here exp denotes an exponential transformation and b, d, r are positive real constants with the objective of normalization.
http://purl.obolibrary.org/obo/OBI_0200109	b transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		A b transformation is a data transformation obtained by applying the function B described in what follows to a (one dimensional) real number input. B(x)= a*exp(b*x)-c*exp(-d*x)+f, where exp denotes an exponential transformation and a, b, c, d, f are real constants with a, b, c, d positive with the objective of normalization.
http://purl.obolibrary.org/obo/OBI_0200110	s transformation	http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation		An s transformation is a data transformation obtained by applying the function S described in what follows to a (one dimensional) real number input. S(x)=T*exp(w-m)*(exp(x-w)-(p^2)*exp((w-x)/p)+p^2-1) if x>=w, S(x)=-S(w-x) otherwise; where exp denotes an exponential_transformations, 'p^' denotes the exponential transformation with base p; T, w, m, p are real constants with T, m, and p positive and w non-negative, and where w and p are related by w=2p*ln(p)(p+1) with the objective of normalization.
http://purl.obolibrary.org/obo/OBI_0200113	similarity calculation	http://purl.obolibrary.org/obo/OBI_0200175	class discovery data transformation		A similarity calculation is a data transformation that attaches to each pair of objects in the input a number that is meant to reflect how 'close' or 'similar' those objects are.
http://purl.obolibrary.org/obo/OBI_0200114	euclidean distance calculation	http://purl.obolibrary.org/obo/OBI_0200113	similarity calculation		An euclidean distance calculation is a similarity calculation that attaches to each pair of real number vectors of the same dimension n the square root of the sum of the square differences between corresponding components. The smaller this number, the more similar the two vectors are considered.
http://purl.obolibrary.org/obo/OBI_0200115	pearson correlation coefficient calculation	http://purl.obolibrary.org/obo/OBI_0200113	similarity calculation		A pearson correlation coefficient calculation is a similarity calculation which attaches to each pair of random variables X and Y the ratio of their covariance by the product of their standard deviations. Given a series of n measurements of X and Y written as x_i and y_i where i = 1, 2, ..., n, then their Pearson correlation coefficient refers to the "sample correlation coefficient" and is written as the sum over i of the ratios (x_i-xbar)*(y_i-ybar)/((n-1)*s_x*s_y) where xbar and ybar are the sample means of X and Y , s_x and s_y are the sample standard deviations of X and Y. The closer the pearson correlation coefficient is to 1, the more similar the inputs are considered.
http://purl.obolibrary.org/obo/OBI_0200116	loess fitting	http://purl.obolibrary.org/obo/OBI_0200072	curve fitting data transformation		A loess fitting is a curve fitting obtained by localized regression. The latter refers to fitting a polynomial (straight line, quadratic, cubic, etc) to data values within a window covering a fraction of the total number of observations. As the window slides along the axis, a new polynomial is fit to the observations falling within the window. This continues until all points are fit with a local polynomial. The results are then smoothed together to form a curve. The smoothness of loess fits is controlled by a smoothing parameter (often denoted as alpha, usually between 1/4 and 1) and the degree of the polynomial that is fitted by the method (usually denoted by lambda).
http://purl.obolibrary.org/obo/OBI_0200117	mode calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A mode calculation is a descriptive statistics calculation in which the mode is calculated which is the most common value in a data set. It is most often used as a measure of center for discrete data.
http://purl.obolibrary.org/obo/OBI_0200118	quantile calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A quantile calculation is a descriptive statistics calculation in which the kth quantile is the data value for which an approximate k fraction of the data is less than or equal to that value.  See http://www.stat.wvu.edu/SRS/Modules/Quantiles/quantiles.html for details.
http://purl.obolibrary.org/obo/OBI_0200119	median calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A median calculation is a  descriptive statistics calculation in which the midpoint of the data set (the 0.5 quantile) is calculated.  First, the observations are sorted in increasing order.  For an odd number of observations, the median is the middle value of the sorted data.  For an even number of observations, the median is the average of the two middle values.
http://purl.obolibrary.org/obo/OBI_0200120	variance calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A variance calculation is a descriptive statistics calculation in which the variance is defined as the average squared distance of each observation in the data set to the mean of the data set.  It is also known as the second central moment.
http://purl.obolibrary.org/obo/OBI_0200121	standard deviation calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A standard deviation calculation is a descriptive statistics calculation defined as the square root of the variance.  Also thought of as the average distance of each value to the mean.
http://purl.obolibrary.org/obo/OBI_0200122	interquartile-range calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		The interquartile range is a descriptive statistics calculation defined as the difference between the 0.75 quantile and the 0.25 quantile for a set of data.
http://purl.obolibrary.org/obo/OBI_0200123	skewness calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A skewness calculation is a descriptive statistics calculation defined as a parameter that describes how much a distribution (or a data set) varies from a bell-shaped curve.  See http://www.riskglossary.com/link/skewness.htm for details.  It is also known as the third central moment
http://purl.obolibrary.org/obo/OBI_0200124	kurtosis calculation	http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation		A kurtosis calculation is a descriptive statistics calculation defined as a parameter that measures how large or small the tails of a distribution are relative to the mean.  For details, see http://davidmlane.com/hyperstat/A53638.html
http://purl.obolibrary.org/obo/OBI_0200126	network graph construction	http://purl.obolibrary.org/obo/OBI_0200080	network analysis		A network analysis in which an input data set describing objects and relationships between objects is transformed into an output representation of these objects as nodes and the relationships as edges of a network graph.
http://purl.obolibrary.org/obo/OBI_0200127	weighted network graph construction	http://purl.obolibrary.org/obo/OBI_0200126	network graph construction		A network graph construction in which an input data set describing objects and quantitative relationships between objects is transformed into and output representation of these objects as nodes and the quantitative relationships as weighted edges of a network graph.
http://purl.obolibrary.org/obo/OBI_0200128	directed network graph construction	http://purl.obolibrary.org/obo/OBI_0200126	network graph construction		A network graph construction in which an input data set describing objects and directional relationships between objects is transformed into and output representation of these objects as nodes and the directional relationships as directed edges of a network graph.
http://purl.obolibrary.org/obo/OBI_0200129	node quality calculation	http://purl.obolibrary.org/obo/OBI_0200080	network analysis		A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the node objects in the network.
http://purl.obolibrary.org/obo/OBI_0200130	node degree calculation	http://purl.obolibrary.org/obo/OBI_0200129	node quality calculation		A node quality calculation in which an input data set describing object nodes and relationship edges between object nodes is used to enumerate the number of unique relationships of an individual object node.
http://purl.obolibrary.org/obo/OBI_0200131	quantitative node degree calculation	http://purl.obolibrary.org/obo/OBI_0200129	node quality calculation		A node quality calculation in which an input data set describing object nodes and quantitative relationship edges between object nodes is used to sum all of the quantitative relationships of an individual object node.
http://purl.obolibrary.org/obo/OBI_0200132	node in-degree calculation	http://purl.obolibrary.org/obo/OBI_0200129	node quality calculation		A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing into an individual object node.
http://purl.obolibrary.org/obo/OBI_0200133	node out-degree calculation	http://purl.obolibrary.org/obo/OBI_0200129	node quality calculation		A node quality calculation in which an input data set describing object nodes and directional relationship edges between object nodes is used to enumerate the number of unique relationships pointing out of an individual object node.
http://purl.obolibrary.org/obo/OBI_0200134	node shortest path identification	http://purl.obolibrary.org/obo/OBI_0200129	node quality calculation		A node quality calculation in which a path describing the shortest path needed to transverse through connected nodes and edges to arrive at a specific target node in the network.
http://purl.obolibrary.org/obo/OBI_0200135	edge quality calculation	http://purl.obolibrary.org/obo/OBI_0200080	network analysis		A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of one of the edge relationships in the network.
http://purl.obolibrary.org/obo/OBI_0200136	edge betweenness calculation	http://purl.obolibrary.org/obo/OBI_0200135	edge quality calculation		An edge quality calculation in which the input is a data sets of shortest paths between all pairs of node in the network and the output is the sum of all shortest paths that traverse the specific edge.
http://purl.obolibrary.org/obo/OBI_0200137	network subgraph quality calculation	http://purl.obolibrary.org/obo/OBI_0200080	network analysis		A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of a subgraph partition of the network.
http://purl.obolibrary.org/obo/OBI_0200138	subgraph degree calculation	http://purl.obolibrary.org/obo/OBI_0200137	network subgraph quality calculation		A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships of an individual subgraph.
http://purl.obolibrary.org/obo/OBI_0200139	quantitative subgraph degree calculation	http://purl.obolibrary.org/obo/OBI_0200137	network subgraph quality calculation		A network subgraph quality calculation in which an input data set describing subgraphs and quantitative relationship edges between subgraphs and other network objects is used to sum the quantitative relationships of an individual subgraph.
http://purl.obolibrary.org/obo/OBI_0200140	mathematical feature	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		feature is a (parent_class) that describes a characteristic, trait or quality of a data transformation
http://purl.obolibrary.org/obo/OBI_0200143	subgraph in-degree calculation	http://purl.obolibrary.org/obo/OBI_0200137	network subgraph quality calculation		A network subgraph quality calculation in which an input data set describing subgraphs and directional relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing into an individual subgraph.
http://purl.obolibrary.org/obo/OBI_0200144	subgraph out-degree calculation	http://purl.obolibrary.org/obo/OBI_0200137	network subgraph quality calculation		A network subgraph quality calculation in which an input data set describing subgraphs and relationship edges between subgraphs and other network objects is used to enumerate the number of unique relationships pointing out of an individual subgraph.
http://purl.obolibrary.org/obo/OBI_0200145	intra subgraph connectivity calculation	http://purl.obolibrary.org/obo/OBI_0200137	network subgraph quality calculation		A network subgraph quality calculation in which an input data set describing internal nodes, edges and node degrees is used to determine the average node degree within the subgraph.
http://purl.obolibrary.org/obo/OBI_0200146	subgraph modularity calculation	http://purl.obolibrary.org/obo/OBI_0200137	network subgraph quality calculation		A network subgraph quality calculation in which an input data set of subgraph in-degree and out-degree qualities is used to calculate the ratio of indegree to outdegree as a measure of modularity.
http://purl.obolibrary.org/obo/OBI_0200147	network graph quality calculation	http://purl.obolibrary.org/obo/OBI_0200080	network analysis		A network analysis in which an input data set describing node objects and edge relationships between node objects is used to determine the output quality of the network as a whole.
http://purl.obolibrary.org/obo/OBI_0200150	MA transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		An MA transformation is a data transformation which takes as input a collection of data points (g_1, r_1), (g_2, r_2), ..., (g_n, r_n)  with the r_i and g_i positive real numbers, and whose output is the collection of data points (A_1, M_1), (A_2, M_2), ..., (A_n, M_n) where, for each i, A_i=(log(g_i)+log(r_i))/2 and M_i=log(r_i)-log(g_i). Here log denotes a logarithmic transformation.
http://purl.obolibrary.org/obo/OBI_0200151	exponential base	http://purl.obolibrary.org/obo/OBI_0200140	mathematical feature		The exponential base is a feature of an exponential function which is defined in http://en.wikipedia.org/wiki/Exponential_function. Its value can be any positive real number (typically different from 1).
http://purl.obolibrary.org/obo/OBI_0200152	polynomial degree	http://purl.obolibrary.org/obo/OBI_0200140	mathematical feature		The polynomial degree is a feature of a polynomial function defined as the highest power of the polynomial's terms, where the terms of a polynomial are the individual summands with the coefficients omitted.
http://purl.obolibrary.org/obo/OBI_0200153	number of variables	http://purl.obolibrary.org/obo/OBI_0200140	mathematical feature		The number of variables is a feature of any function (including polynomial functions) with domain contained in an n-dimensional vector space and is defined as n, the dimension of such space.
http://purl.obolibrary.org/obo/OBI_0200156	data partitioning	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		Data partitioning is a data transformation with the objective of partitioning or separating input data into output subsets.
http://purl.obolibrary.org/obo/OBI_0200157	data vector reduction objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		Data vector reduction is a data transformation objective in which k m-dimensional input vectors are reduced to j m-dimensional output vectors, where j is smaller than k.
http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective	http://purl.obolibrary.org/obo/IAO_0000005	objective specification		An objective specification to transformation input data into output data
http://purl.obolibrary.org/obo/OBI_0200167	data normalization objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A normalization objective is a data transformation objective where the aim is to remove
systematic sources of variation to put the data on equal footing in order
to create a common base for comparisons.
http://purl.obolibrary.org/obo/OBI_0200168	correction objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A correction objective is a data transformation objective where the aim is to correct for error, noise or other impairments to the input of the data transformation or derived from the data transformation itself
http://purl.obolibrary.org/obo/OBI_0200169	normalization data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A normalization data transformation is a data transformation that has objective normalization.
http://purl.obolibrary.org/obo/OBI_0200170	averaging data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		An averaging data transformation is a data transformation that has objective averaging.
http://purl.obolibrary.org/obo/OBI_0200171	partitioning data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A partitioning data transformation is a data transformation that has objective partitioning.
http://purl.obolibrary.org/obo/OBI_0200172	partitioning objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A partitioning objective is a data transformation objective where the aim is to generate a collection of disjoint non-empty subsets whose union equals a non-empty input set.
http://purl.obolibrary.org/obo/OBI_0200173	background correction objective	http://purl.obolibrary.org/obo/OBI_0200168	correction objective		A background correction objective is a data transformation objective where the aim is to remove irrelevant contributions from the measured signal, e.g. those due to instrument noise or sample preparation.
http://purl.obolibrary.org/obo/OBI_0200174	curve fitting objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A curve fitting objective is a data transformation objective in which the aim is to find a curve which matches a series of data points and possibly other constraints.
http://purl.obolibrary.org/obo/OBI_0200176	Fisher's exact test	http://purl.obolibrary.org/obo/OBI_0000673	statistical hypothesis test		Fisher's exact test is a data transformation used to determine if there are nonrandom associations between two Fisher's exact test is a statistical significance test used in the analysis of contingency tables where sample sizes are small where the significance of the deviation from a null hypothesis can be calculated exactly, rather than relying on an approximation that becomes exact in the limit as the sample size grows to infinity, as with many statistical tests.
http://purl.obolibrary.org/obo/OBI_0200177	center calculation objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A center calculation objective is a data transformation objective where the aim is to calculate the center of an input data set.
http://purl.obolibrary.org/obo/OBI_0200180	spread calculation objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		is a data transformation objective whereby the aim is to the calculate the spread of a dataset, spread is a descriptive statistic which describes the variability of values in a data set.
http://purl.obolibrary.org/obo/OBI_0200181	center calculation data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A center calculation data transformation is a data transformation that has objective of center calculation.
http://purl.obolibrary.org/obo/OBI_0200182	data vector reduction data transformation	http://purl.obolibrary.org/obo/OBI_0000707	decision tree building data transformation		A data vector reduction is a data transformation that has objective data vector reduction and that consists of reducing the input vectors k to a smaller number of output vectors j, where j<k.
http://purl.obolibrary.org/obo/OBI_0200183	scaling objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		is a data transformation objective where all, or some of a data set is adjusted by some data transformation according to some scale, for example a user defined minimum or maximum
http://purl.obolibrary.org/obo/OBI_0200184	descriptive statistical calculation data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A descriptive statistical calculation data transformation is a data transformation that has objective descriptive statistical calculation and which concerns any calculation intended to describe a feature of a data set, for example, its center or its variability.
http://purl.obolibrary.org/obo/OBI_0200185	scaling data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A scaling data transformation is a data transformation that has objective scaling.
http://purl.obolibrary.org/obo/OBI_0200186	error correction objective	http://purl.obolibrary.org/obo/OBI_0200168	correction objective		An error correction objective is a data transformation objective where the aim is to remove (correct for) erroneous contributions arising from the input data, or the transformation itself.
http://purl.obolibrary.org/obo/OBI_0200187	sequence analysis data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A sequence analysis data transformation is a data transformation that has objective sequence analysis and has the aim of analysing ordered biological data for sequential patterns.
http://purl.obolibrary.org/obo/OBI_0200190	clustered data visualization	http://purl.obolibrary.org/obo/OBI_0200111	data visualization		A data visualization which has input of a clustered data set and produces an output of a report graph which is capable of rendering data of this type.
http://purl.obolibrary.org/obo/OBI_0200191	gene list visualization	http://purl.obolibrary.org/obo/OBI_0200111	data visualization		Adata visualization which has input of a gene list and produces an output of a report graph which is capable of rendering data of this type.
http://purl.obolibrary.org/obo/OBI_0200192	classified data visualization	http://purl.obolibrary.org/obo/OBI_0200111	data visualization		A data visualization which has input of a classified data set and produces an output of a report graph which is capable of rendering data of this type.
http://purl.obolibrary.org/obo/OBI_0200193	background corrected data visualization	http://purl.obolibrary.org/obo/OBI_0200111	data visualization		A data visualization which has input of a background corrected data set and produces an output of a report graph which is capable of rendering data of this type.
http://purl.obolibrary.org/obo/OBI_0200194	survival analysis data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation which has the objective of performing survival analysis.
http://purl.obolibrary.org/obo/OBI_0200196	correlation study objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		A data transformation objective in which correlation is obtained (often measured as a correlation coefficient, ρ) which indicates the strength and direction of a relationship between two random variables.
http://purl.obolibrary.org/obo/OBI_0200197	spectrum analysis objective	http://purl.obolibrary.org/obo/OBI_0200166	data transformation objective		is a data transformation objective where the aim is to analyse some aspect of spectral data by some data transformation process.
http://purl.obolibrary.org/obo/OBI_0200198	obsolete tandem mass spectrometry	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		Tandem mass spectrometry is a data transformation that uses two or more analyzers separated by a region in which ions can be induced to fragment by transfer of energy (frequently by collision with other molecules.
http://purl.obolibrary.org/obo/OBI_0200199	gas chromatography mass spectrometry	http://purl.obolibrary.org/obo/OBI_0200085	mass spectrometry analysis		Gas chromatography mass spectrometry is a data transformation combining mass spectrometry and  
gas chromatography for the qualitative as well as quantitative  
determinations of compounds.
http://purl.obolibrary.org/obo/OBI_0200200	chi square test	http://purl.obolibrary.org/obo/OBI_0000673	statistical hypothesis test		The chi-square test is a data transformation with the objective of statistical hypothesis testing, in which the sampling distribution of the test statistic is a chi-square distribution when the null hypothesis is true, or any in which this is asymptotically true, meaning that the sampling distribution (if the null hypothesis is true) can be made to approximate a chi-square distribution as closely as desired by making the sample size large enough.
http://purl.obolibrary.org/obo/OBI_0200201	ANOVA	http://purl.obolibrary.org/obo/OBI_0000673	statistical hypothesis test		A statistical hypothesis test in which the means of several groups are all equal.
http://purl.obolibrary.org/obo/OBI_0300310	sequential design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		Any design in which the decision as to whether to enroll the next patient, pair of patients, or block of patients is determined by whether the cumulative treatment difference for all previous patients is within specified limits.  Enrollment is continued if the difference does not exceed the limits.  It is terminated if it does
http://purl.obolibrary.org/obo/OBI_0300311	observation design	http://purl.obolibrary.org/obo/OBI_0500000	study design		observation design is a study design in which subjects are monitored in the absence of any active intervention by experimentalists.
http://purl.obolibrary.org/obo/OBI_0302716	pool of specimens	http://purl.obolibrary.org/obo/OBI_0000953	processed specimen		A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g.  mixing the DNA collected from the individual fish.
http://purl.obolibrary.org/obo/OBI_0302732	solvent role	http://purl.obolibrary.org/obo/OBI_0003610	reactant role		solvent role is a role which inheres in a molecular entity capable of ensuring the dissolution of another chemical entity and realized by the process of solvation
http://purl.obolibrary.org/obo/OBI_0302733	solute role	http://purl.obolibrary.org/obo/BFO_0000023	role		solute role is a role played by a chemical entity which is dissolved by another chemical entity (the solvent) when creating a solution
http://purl.obolibrary.org/obo/OBI_0302743	obsolete_liver	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		liver is an anatomical entity which constituent are mainly hepatocytes, which has a function of detoxification, hematopoietic center, glucose and fat metabolism management. liver is only found in animals , all Vertebrates and some families of invertebrates
http://purl.obolibrary.org/obo/OBI_0302745	obsolete_adipose tissue	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		adipose tissue is a tissue which main constituents are adipocytes. adipose tissue can be classified base on its location (site) but also based on adipocyte subtypes (brown or white) which reflect functional differences and is only found in animals, Vertebrates or invertebrates.
http://purl.obolibrary.org/obo/OBI_0302835	denatured polymer	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		Is a polymer which has lost secondary or tertiary structure
http://purl.obolibrary.org/obo/OBI_0302837	decapitated organism	http://purl.obolibrary.org/obo/OBI_0000047	processed material		decapitated organism is an organism which has had it's head removed
http://purl.obolibrary.org/obo/OBI_0302838	validated information	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		an information content entity which results from a validation process aimed at confirming a claim, a finding or a predicted information entity about a material entity or a process by experimental means.
http://purl.obolibrary.org/obo/OBI_0302840	curated information	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that has undergone a digital curation performed by a curator for accuracy checks and compliance with curation requirements. Information which has been assessed for accuracy by domain experts.
http://purl.obolibrary.org/obo/OBI_0302846	randomized group participant role	http://purl.obolibrary.org/obo/BFO_0000023	role		a role that borne by an organism and realized by some group randomization process
http://purl.obolibrary.org/obo/OBI_0302847	methylated polymer	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		A methylated polymer which has artificially acquired one or more methyl groups
http://purl.obolibrary.org/obo/OBI_0302859	genetically modified organism	http://purl.obolibrary.org/obo/OBI_0100026	organism		an organism that is the output of a genetic transformation process
http://purl.obolibrary.org/obo/OBI_0302867	predicted data item	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that was generated on the basis of a calculation or logical reasoning
http://purl.obolibrary.org/obo/OBI_0302868	mean-centered data	http://purl.obolibrary.org/obo/OBI_0000451	normalized data set		a data item which has been processed by a mean centering data transformation where each output value is produced by subtracting the mean from the inout value
http://purl.obolibrary.org/obo/OBI_0302874	edited document	http://purl.obolibrary.org/obo/IAO_0000310	document		A document which is the output of a document editing process
http://purl.obolibrary.org/obo/OBI_0302876	dissolved material entity	http://purl.obolibrary.org/obo/OBI_0000576	scattered molecular aggregate		A material entity that has been going through a process of being put into solution
http://purl.obolibrary.org/obo/OBI_0302884	extraction	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		A material separation in which a desired component of an input material is separated from the remainder
http://purl.obolibrary.org/obo/OBI_0302885	filtration	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		filtration is a process which separates components suspended in a fluid based on granularity properties relying on a filter device
http://purl.obolibrary.org/obo/OBI_0302886	centrifugation	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		centrifugation is a process separating molecules by size or density using centrifugal forces generated by a spinning rotor. G-forces of several hundred thousand times gravity are generated in ultracentrifugation
http://purl.obolibrary.org/obo/OBI_0302887	staining	http://purl.obolibrary.org/obo/OBI_0000094	material processing		Staining is a process which results in the addition a class-specific (DNA, proteins, lipids, carbohydrates) dye to a substrate to qualify or quantify the presence of a specific compound.
http://purl.obolibrary.org/obo/OBI_0302888	washing	http://purl.obolibrary.org/obo/OBI_0000094	material processing		washing is a process by which a material entity acting as  contaminant (e.g. excess staining reagent) is removed by application of one or more cycles of solution in flow.
http://purl.obolibrary.org/obo/OBI_0302889	planned irradiation	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A planned process by which a material entity is exposed to radiative energy, which could be ionizing radiation (such as gamma rays, X-rays, charged particles or neutrons) or non-ionizing radiation (such as UV light or microwaves)
http://purl.obolibrary.org/obo/OBI_0302890	polymerization	http://purl.obolibrary.org/obo/OBI_0000094	material processing		polymerization is process by which molecular entity of small mass are aggregated in motifs over the course of a chemical reaction catalyzed by enzymes or other molecular entities acting as catalyst. polymerization results in molecular entity of high molecular weight
http://purl.obolibrary.org/obo/OBI_0302891	trypsination	http://purl.obolibrary.org/obo/OBI_0600056	protease cleavage		trypsination is a protease cleavage which uses enzyme trypsin to act on proteins present in an input material entity
http://purl.obolibrary.org/obo/OBI_0302892	enzymatic ligation	http://purl.obolibrary.org/obo/OBI_0000094	material processing		An enzymatic ligation is a planned process in which molecules  are joined by covalent bonds through the action of an material entity with a ligase activity
http://purl.obolibrary.org/obo/OBI_0302893	storage	http://purl.obolibrary.org/obo/OBI_0000838	material maintenance		A planned process with the objective to preserve and protect material entities by placing them in an identified location which may have a controlled environment.
http://purl.obolibrary.org/obo/OBI_0302894	cell lysis	http://purl.obolibrary.org/obo/OBI_0600006	killing		cell lysis is a process by which cell membrane integrity of live cells  is compromised and leads to cell death. Cell lysis may be achieved by means of viral action or osmotic shock.
http://purl.obolibrary.org/obo/OBI_0302895	electrocution	http://purl.obolibrary.org/obo/OBI_0000919	animal euthanization		electrocution is process by which electric current is applied to a material with quality alive and result the termination of life process.
http://purl.obolibrary.org/obo/OBI_0302896	cervical dislocation	http://purl.obolibrary.org/obo/OBI_0000919	animal euthanization		cervical dislocation is a process by which a Vertebrate organism has its life terminated by rupturing spinal cord between cervical vertebrae induced by excessive mechanical torsion
http://purl.obolibrary.org/obo/OBI_0302897	asphyxiation	http://purl.obolibrary.org/obo/OBI_0000919	animal euthanization		asphyxiation is a process by which oxygen supplies are restricted (by mechanical, e.g obstructing airways or chemical means, e.g. increasing CO2 partial pressure) resulting in termination of life in oxygen reliant organisms.
http://purl.obolibrary.org/obo/OBI_0302899	decapitation	http://purl.obolibrary.org/obo/OBI_0000919	animal euthanization		decapitation is a process by which the head of a living organism is physically removed from the body, usually resulting in rapid death (in the case of Rhodnius prolixus, it might take a bit longer..)
http://purl.obolibrary.org/obo/OBI_0302900	group randomization	http://purl.obolibrary.org/obo/OBI_0600015	group assignment		A group assignment which relies on chance to assign materials to a group of materials in order to avoid bias in experimental set up.
http://purl.obolibrary.org/obo/OBI_0302901	obsolete_activation	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		a process by which a material entity status is modified and conferred a capability of reacting (this sounds like a circular definition , hugh!)
http://purl.obolibrary.org/obo/OBI_0302902	immobilization	http://purl.obolibrary.org/obo/OBI_0000094	material processing		immbolization is a process by which material entity become (possibly covalently but not necessarily) attached to the surface of another material entity used a substratum.
http://purl.obolibrary.org/obo/OBI_0302903	nucleic acid hybridization	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a planned process by which totally or partially complementary, single-stranded nucleic acids are  combined into a single molecule called heteroduplex or homoduplex to an extent depending on the amount of complementarity.
http://purl.obolibrary.org/obo/OBI_0302905	elution	http://purl.obolibrary.org/obo/OBI_0000094	material processing		the process of extracting one material from another by washing with a solvent to remove adsorbed material from an adsorbent (as in washing of loaded ion-exchange resins to remove captured ions)
http://purl.obolibrary.org/obo/OBI_0302906	DNA Subtraction	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a material separation process by which repetitive genomic DNA is removed during the construction of cDNA library.
http://purl.obolibrary.org/obo/OBI_0302908	document editing	http://purl.obolibrary.org/obo/OBI_0000011	planned process		is a planned process with specified input original document and specified output edited document
http://purl.obolibrary.org/obo/OBI_0302910	prediction	http://purl.obolibrary.org/obo/OBI_0000011	planned process		a process by which an  event or an entity is described before it actually happens or is being discovered and identified.
http://purl.obolibrary.org/obo/OBI_0302911	validation	http://purl.obolibrary.org/obo/OBI_0000011	planned process		a planned process with objective to check that the accuracy or the quality of a claim or prediction  satisfies some criteria and which is assessed by comparing with independent results
http://purl.obolibrary.org/obo/OBI_0302914	digital curation	http://purl.obolibrary.org/obo/IAO_0000572	documenting		Digital curation is the process of establishing and developing long term repositories of digital assets for current and future reference by researchers, scientists, and historians, and scholars generally.
http://purl.obolibrary.org/obo/OBI_0400005	A10-Analyzer	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A A10 is a flow_cytometer_analyser manufactured by Apogee. It uses an arc lamp as a light source, with choices of 75W Xe, 75W Xe/Hg or 100W Hg arc lamps. It has filters and collectors for up to three fluorescent parameters and two scatter parameters. It uses analog electronics. The A10 can be used for measuring the properties of individual cells.
http://purl.obolibrary.org/obo/OBI_0400006	A40-MiniFCM	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A A40-MiniFCM is a flow_cytometer_analyser that allows for the choice of one of four lasers (375nm, 405nm,488nm, 532nm, 635nm), and PMTs and filters for collecting up to four parameters. It uses digital electronics. A military version of this cytometer is available as well. The A40-MiniFCM is geared towards the most demanding applications such as archaea, bacteria and large virus.
http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer	http://purl.obolibrary.org/obo/OBI_0400044	flow cytometer		An analyser is a flow_cytometer that is used to measure properties of particles (whole cells, nuclei, chromosomes, diatoms, plankton, bacteria, viruses) by moving these particles through a detection chamber. An analyser is used to collect data for analysis.
http://purl.obolibrary.org/obo/OBI_0400009	arc lamp	http://purl.obolibrary.org/obo/OBI_0400065	light source		Arc lamp is a light source that produces light by an electric arc (or voltaic arc). The lamp consists of two electrodes typically made of tungsten which are separated by a gas. The type of lamp is often named by the gas contained in the bulb; including neon, argon, xenon, krypton, sodium, metal halide, and mercury. The electric arc in an arc lamp consists of gas which is initially ionized by a voltage and is therefore electrically conductive. To start an arc lamp, usually a very high voltage is needed to ignite or strike the arc. This requires an electrical circuit sometimes called an igniter, which is part of a larger circuit called the ballast. The ballast supplies a suitable voltage and current to the lamp as its electrical characteristics change with temperature and time. Older cytometers may use arc lamps to irradiate particles at the interrogation point.
http://purl.obolibrary.org/obo/OBI_0400010	argon ion laser	http://purl.obolibrary.org/obo/OBI_0400060	ion laser		An argon-ion laser is an ion laser that uses argon ions as the lasing medium. These lasers are used primarily to emit light at wave lengths of 458 nm, 488 nm or 514.5 nm, though it is possible to use them to emit several wavelengths of blue and green light. Argon-ion lasers can emit light at many different wave lenghts, and excite a number of different flourochromes.
http://purl.obolibrary.org/obo/OBI_0400011	avalanche photodiode	http://purl.obolibrary.org/obo/OBI_0400083	photodiode		An avalanche photodiode is typically used to collect photons emitted by forward scatter because it is far less sensitive, and less likely o be burned out, than a PMT. A photodiode with high quantum efficiency and a mechanism for producing gains as high as a few thousand.
http://purl.obolibrary.org/obo/OBI_0400012	Bactiflow	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A Bactiflow is a flow_cytometer_analyser manufactured by Chemunex SA. It is a cell counter for bacteria and other micro organisms. Bacteria are stained with a fluorochrome and the number of particles that fluoresce are counted. The system uses digital electronics, a single laser and a single detector. An ALS version is available as well - Automatic Labeling System. The Bactiflow is specialized cytometer used exclusively for counting microbes.
http://purl.obolibrary.org/obo/OBI_0400013	band pass filter	http://purl.obolibrary.org/obo/OBI_0400079	optical filter		A band pass filter is an optical filter that passes wavelengths of light within a certain range and rejects (attenuates) frequencies outside that range. The passed wavelengths are indicated in the specifications of the filter and its name. A 480/20 band-pass filter pass light with at wavelengths of 460 to 500 nm and attenuates all others.
http://purl.obolibrary.org/obo/OBI_0400014	BioSorter1000	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A BioSorter1000 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 1000 is an instrument for analyzing and sorting objects from 200-600 microns in diameter.
http://purl.obolibrary.org/obo/OBI_0400015	BioSorter2000	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A BioSorter2000 is a sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 2000 is an instrument for analyzing and sorting objects from 500 microns to 1.5 millimeters in diameter.
http://purl.obolibrary.org/obo/OBI_0400016	BioSorter250	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A BioSorter250 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 250 is an instrument for analyzing and sorting objects from 40-200 microns in diameter.
http://purl.obolibrary.org/obo/OBI_0400017	BioSorter500	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A BioSorter500 is a flow_cytometer_sorter manufactured by Union Biometrica. It includes analog electronics, 488/514 nm multi-line Argon-ion laser for fluorescence and a light stabilized 670 nm forward scatter laser for extinction and time-of-flight. It has filters and PMTs for 3 fluorescent parameters and photodiodes for scatter, time of flight, and extinction. The flow cell is quartz cuvette. The BioSorterTM 500 is an instrument for analyzing and sorting objects from 100-250 microns in diameter and less than 2mm in length.
http://purl.obolibrary.org/obo/OBI_0400018	Cell Lab Quanta SC	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A Cell Lab Quanta SC is a flow_cytometer_analyser manufactured by Becman Coulter. It features a mercury arc lamp optimized at 366, 405, and 435 nm, and a 488 nm laser diode. It has filters and PMTs to collect up to 3 fluorescent parameters, and a photodiode for side scatter detection. This cytometer uses Couter-Volume for cell size measurements. The Cell Lab Quanta SC can be used for measuring the properties of individual cells.
http://purl.obolibrary.org/obo/OBI_0400019	charge plate	http://purl.obolibrary.org/obo/OBI_0000968	device		Part of the fluidics subsystem. Charge plates are used or sorters. They create an charged electric field when particles deemed to be desired for further analysis are shaken form the piexo electric crystal. The charged particles are drawn toward the charged plate, and the altered drop location causes the particles to fall into a collection tube. Charge plates enable sorting.
http://purl.obolibrary.org/obo/OBI_0400020	cell sorter collection tube	http://purl.obolibrary.org/obo/OBI_0000836	test tube		Part of the fluidics subsystem. The collection tube is a vessel for capturing cells of interest that have been identified by a sorter. The collection tube is the end location of sorted cells.
http://purl.obolibrary.org/obo/OBI_0400022	Cyan	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A Cyan is a flow_cytometer_analyser manufactured by Dako Cytomation. It features include digital electronics, three lasers: 488 nm, 635 nm, and 405 nm, and filters and collectors for nine fluorescent parameters and two scatter parameters. The Cyan can be used for measuring the properties of individual cells.
http://purl.obolibrary.org/obo/OBI_0400023	CYFlow ML	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A CyFlow_ML is a flow_cytometer_analyser manufactured by Partec. It is a digital machine which uses 4 light sources: triple laser configurations including new powerful 200mW@488nm blue solid state laser + 100W UV lamp for highest resolution DNA analysis, and can collect 16 optical parameters: FSC1, FSC2, SSC, FL1-FL13. Ultracompact high end desktop multilaser Flow Cytometer for all applications in cell analysis and absolute counting.
http://purl.obolibrary.org/obo/OBI_0400024	CyFlow SL	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37, highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser , other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing Compact mobile Flow Cytometer for any kind of cell analysis and absolute volumetric counting. The CyFlow_SL allows to analyze forward and side scatter signals in combination with up to 3 fluorescence channels.
http://purl.obolibrary.org/obo/OBI_0400025	CyFlow SL3	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A CyFlow_Sl3 is a flow_cytometer_analyser manufactured by Partec. Its specs are: ultracompact and fully equipped mobile/portable instrument, dimensions [cm]: L 43 x H 16 x D 37 , highest stability/robustness and highest precision, 5 optical parameters: FSC, SSC, FL-1, FL-2, FL-3, 20mW@488nm blue solid state laser, other laser light sources optional (UV, violet, green, red), WindowsTM XP FloMax (software for real time data acquisition, data display, and data evaluation), parallel 16 bit digital pulse processing. The CyFlow SL3 is a compact and dedicated portable Flow Cytometer for accurate and affordable cell analysis and true volumetric absolute counting in HIV Monitoring and AIDS patient follow-up by precise and direct CD4 and CD4% measurement.
http://purl.obolibrary.org/obo/OBI_0400026	CyFlow Space	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A CyFlow_Space is a flow_cytometer_sorter manufactured by Partec. Its specs are: 8optical parameters, 6 colours:FSC, SSC, FL1-FL6 , 3laser light sources: 200mW@488nm blue solid state laser 25mW@635nm red diode laser 50mW@405nm violet or 8mW@375nm ultraviolet diode laser _ultracompact desktop high end instrument. Parallel 16bit digital pulse processing. The CyFlow Space is a 6-Colour FCM System and Cell Sorter for Clinical Routine and Research.
http://purl.obolibrary.org/obo/OBI_0400027	CytoBuoy flow cytometer analyzer	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A flow cytometer analyser which is manufactured by Cyto Buoy Inc. They are the buoy mounted version of the CytoSense, equipped with wireless transmission of control and data files. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters.
http://purl.obolibrary.org/obo/OBI_0400028	CytoSence	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A CytoSense is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSense is the basic instrument, which can be used for normal laboratory applications, as well as for autonomous monitoring with internal data logging or direct data transmission. The special instrument design and its splashproof housing allow operation on moving platforms and outdoor sites.
http://purl.obolibrary.org/obo/OBI_0400029	CytoSub	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A CytoSub is a flow_cytometer_analyser manufactured by Cyto Buoy Inc. They are a single laser, multi parameter instrument. Various types of micro-laser are offered; available measuring parameters are forward light scatter, side scatter, and fluorescence (max. 9 colour bands). The current series have 5 parameters. The CytoSub is the submersible version equipped with a high pressure sample inlet loop and a high pressure housing to allow underwater operation down to 200 m, lowered on a cable or mounted on a flooded underwater vehicle.
http://purl.obolibrary.org/obo/OBI_0400030	dichroic filter	http://purl.obolibrary.org/obo/OBI_0400079	optical filter		A dichroic filter is an optical filter which is used to selectively pass light of a small range of colors while reflecting other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.
http://purl.obolibrary.org/obo/OBI_0400031	dichroic mirror	http://purl.obolibrary.org/obo/OBI_0400079	optical filter		A dichroic mirror is an optical filter which is used to selectively reflect light of a small range of colors while passing other colors. A dichroic filter passes the specified range of light whereas a dichroic mirror reflects the specified range of light.
http://purl.obolibrary.org/obo/OBI_0400032	differential pressure gauge	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		Part of the fluidics subsystem. The differential pressure gauge monitors the difference between sample and sheath fluid pressures in systems where pressure is used to force the sample fluid to flow in the center of the sheath fluid. A differential pressure gauge can be used by the operator to make sure that the sample fluid is at a greater pressure than the sheath fluid, which maintains a core of sample fluid.
http://purl.obolibrary.org/obo/OBI_0400033	diode laser	http://purl.obolibrary.org/obo/OBI_0400064	laser		A diode laser is a laser in which the active medium is a p-n junction semiconductor laser diode, similar to that found in a light-emitting diode. Laser diodes emit at wavelengths from 375 nm to 1800 nm, and wavelengths of over 3 micrometer have been demonstrated. A diode laser can by used to irradiate cells in a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0400034	dye laser	http://purl.obolibrary.org/obo/OBI_0400064	laser		A dye laser is a laser in which the lasing medium is a fluorescent dye, usually dissolved in an organic solvent such as ethanol or ethylene glycol. The particular dye used determines the wavelengths the laser can emit. The laser medium is places between two parallel mirrors for light emission amplification.
http://purl.obolibrary.org/obo/OBI_0400036	FACS Calibur	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		The FACS Calibur is one of the most popular cytometers in use for research.
http://purl.obolibrary.org/obo/OBI_0400037	FACS Canto	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A FACS_Canto is a flow_cytometer_analyser manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm, and a HeNe 633 nm lasers, and filters and PMTs for collecting up to 6 fluorescent parameters. The FACS_Canto is an analyser usually used in clinical applications.
http://purl.obolibrary.org/obo/OBI_0400038	FACS Canto2	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A FACS_Canto2 is a flow_cytometer_analyser manufactured by BD. It features digital electronics, two solid state lasers at 488 and 633 nm with the option for a third 405 nm laser, and filters and collectors for measuring up to 8 fluorescent paramters with either the 2 or 3 laser option. The FACS_Canto2 is an analyser usually used in clinical applications.
http://purl.obolibrary.org/obo/OBI_0400039	FACS Scan	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A FACS_Scan is a flow_cytometer_analyser manufactured by Becton Dickinson. IT features analog electronics, one 488 nm solid state laser, and the filters and PMTs to collect up to three fluorescent parameters The FACS_Scan is usually used for research applications.
http://purl.obolibrary.org/obo/OBI_0400040	FACSAria	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A FASCSAria is a flow_cytometer_sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser, a solid state 407 nm violet laser, and a HeNe (633 nm) ion laser. The Aria has the filters and PMTs to collect side scatter and 9 fluorescent parameters. The Aria has a photodiode detector for forward scatter collector. The flow cell is Quartz cuvette. The FACSAria is a sorter used to collect and analyse cells using up to 11 parameters.
http://purl.obolibrary.org/obo/OBI_0400041	FACSvantage	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		The FACSvantage is a flow_cytometer_sorter manufactured by Becton Dickinson. It has analog electronics, three lasers (several options are available), and the filters and PMTs to collect 6 fluorescent parameters and side scatter, and a photodiode to collect forward scatter. The FACSvantage can be used to analyse, sort and collect cells.
http://purl.obolibrary.org/obo/OBI_0400042	FC 500	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A FC_500 is a flow_cytometer_analyser manufactured by Beckman Coulter. It features digital electronics, 488 nm and 635 nm lasers, filters and PMTs for 5 fluorescent parameters, a diode for collecting side scatter and a solid state detector for forward scatter. The FC 500 is an analyser usually used for either research or clinical applications.
http://purl.obolibrary.org/obo/OBI_0400044	flow cytometer	http://purl.obolibrary.org/obo/OBI_0400137	cytometer		A flow_cytometer is an instrument for counting, examining and sorting microscopic particles in suspension. It allows simultaneous multiparametric analysis of the physical and/or chemical characteristics of single cells flowing through an optical and/or electronic detection apparatus. A flow cytometer is an instrument that can be used to quantitatively measure the properties of individual cells in a flowing medium.
http://purl.obolibrary.org/obo/OBI_0400045	fluid pressure regulator	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		Part of the fluidic subsystem. The fluid pressure regulator maintains constant pressure within the sheath and or sample lines by filling the lines with enough gas to push the fluid at the desired rate. The gas is usually air, and less frequently nitrogen. In the sheath line, the gas is pushed into the sheath tank. In the sample line the gas is pushed into the collection tube. Fluid pressure regulators maintain great enough pressure to push sample fluid out of the tube and sheath fluid out of the sheath tank.
http://purl.obolibrary.org/obo/OBI_0400047	gas laser	http://purl.obolibrary.org/obo/OBI_0400064	laser		A gas laser is a laser in which the lasing medium is a gas. The laser medium is places between two parallel mirrors for light emission amplification. The gas is excited to emit light via an external light source or an electric current discharging through the gas.
http://purl.obolibrary.org/obo/OBI_0400048	Guava EasyCyte Mini	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A Guava_EasyCyte_Mini is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 3 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The mini accepts tubes only for inputting cells or beads. The Guava_EasyCyte_Mini cytometer is a small portable cytometer particularly useful for field measurement.
http://purl.obolibrary.org/obo/OBI_0400049	Guava EasyCyte Plus	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A Guava_EasyCyte_Plus System is a flow_cytometer_analyser that includes a single 488 nm laser, and filters and PMTs to collect up to 4 fluorescent parameters. It includes a photodiode forward scatter collector and an optional photodiode for side scatter collection.Guava cytometers use aspiration instead of fluid systems to transport cells within the machine. The EasyCyte plus accepts 96 well plates as well as tubes. The Guava_EasyCyte_Plus cytometer is a small portable cytometer particularly useful for field measurement.
http://purl.obolibrary.org/obo/OBI_0400052	helium cadmium ion laser	http://purl.obolibrary.org/obo/OBI_0400073	metal vapor laser		A helium-cadmium laser is a metal vapor laser that emits wavelengths of 442, 325 and 354 nms. This laser is a metal vapor laser. A helium-cadmium laser can by used to irradiate cells in a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0400053	helium neon ion laser	http://purl.obolibrary.org/obo/OBI_0400060	ion laser		A helium-neon laser (HeNe) is an ion laser that uses helium and neon gas-ions as lasing medium. HeNe lasers emit at 543 nm and 633 nm most commonly and can also be used at 543, 594, and 611 nm.
http://purl.obolibrary.org/obo/OBI_0400054	Amnis ImageStream	http://purl.obolibrary.org/obo/OBI_0400146	multispectral imaging flow cytometer		The ImageStream is a multispectral_imaging_flow_cytometer manufactured by Amnis. Its has digital electronics, a single standard 488 nm solid state laser. In addition an optional 658 nm and your choice of either a 405 nm or 375 nm solid state laser can be added. Information is collected using cameras. The ImageStream system CCD camera produces six images of each cell, including darkfield, brightfield, and up to four fluorescent colors. Each image is used to calculate over 40 features, so a six-image assay results in ~250 morphometric and photometric features per cell. The ImageStream is a flow cytometer that takes pictures of the cells in flow. It has both components, an Image cytometer and a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0400055	inFlux Analyzer	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		The inFlux Analyzer is a flow_cytometer_analyser manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx analyser can be used to measure the properties of individual cells.
http://purl.obolibrary.org/obo/OBI_0400056	Influx Cell Sorter	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A Influx Cell Sorter is a flow_cytometer_sorter manufactured by Cytopeia. It is a digital machine, with these laser options: Coherent 70, 90, 300 series water cooled lasers, solid state UV 355nm, Violet 408nm, Violet-Blue 479nm, Blue-488nm, Green-531nm, Red-635nm, Red-647nm. The sorting is multi-way, index, and proportional sorting. Filters and PMTs are used for all parameters (including forward light scatter), and up to 12 PMTs can be included. The Influx cell sorter can be used to measure, sort, and collect ndividual cells.
http://purl.obolibrary.org/obo/OBI_0400059	interrogation_point	http://purl.obolibrary.org/obo/BFO_0000029	site		Point within the fluidic subsystem at which the laser intersects the stream, illuminating the cells where they emit their fluorescence and scatter the light. The laser irradiates the cell at the interrogation point.
http://purl.obolibrary.org/obo/OBI_0400060	ion laser	http://purl.obolibrary.org/obo/OBI_0400047	gas laser		An ion laser is a gas laser which uses an ionized gas as its lasing medium.
http://purl.obolibrary.org/obo/OBI_0400061	jet_in_air_flow_chamber	http://purl.obolibrary.org/obo/BFO_0000029	site		A flow cell in which the cells are pinched off as droplets and allowed to drop through the air. The laser intersects with the cell in mid-air. A jet in air flow chamber allows the laser to intersect with the cells without any intermittent media other than air.
http://purl.obolibrary.org/obo/OBI_0400062	krypton ion laser	http://purl.obolibrary.org/obo/OBI_0400060	ion laser		A krypton-ion laser is an ion laser that uses krypton as the lasing medium. These lasers can emit at 468, 476, 482, 520, 531, 568, 647 (the most powerful line), and 676 nm all at once. They have much lower gain than argon lasers however.
http://purl.obolibrary.org/obo/OBI_0400063	LactoScope C4	http://purl.obolibrary.org/obo/OBI_0400115	spectrophotometer		A LactoScope_C4 is a spectrophotometer with which the composition of milk and milk products is analysed via infrared technology. The LactoScope determines the amount of the constituents fat, protein, lactose and the total solids content with extreme accuracy.
http://purl.obolibrary.org/obo/OBI_0400065	light source	http://purl.obolibrary.org/obo/OBI_0001032	light emission device		A light source is an optical subsystem that provides light for use in a distant area using a delivery system (e.g., fiber optics). Light sources may include one of a variety of lamps (e.g., xenon, halogen, mercury). Most light sources are operated from line power, but some may be powered from batteries. They are mostly used in endoscopic, microscopic, and other examination and/or in surgical procedures. The light source is part of the optical subsystem. In a flow cytometer the light source directs high intensity light at particles at the interrogation point. The light source in a flow cytometer is usually a laser.
http://purl.obolibrary.org/obo/OBI_0400066	logarithmic voltage amplifier	http://purl.obolibrary.org/obo/OBI_0400101	voltage amplifier		A logarithmic voltage amplifier is an analog electronic circuit that puts out a voltage or current proportional to the voltage or current at its input, with logarithmic proportionality. In an analog system, the logarithmic voltage amplifier is used to present parameters with a high dynamic range on a more useful scale.
http://purl.obolibrary.org/obo/OBI_0400067	long pass filter	http://purl.obolibrary.org/obo/OBI_0400079	optical filter		A long pass filter is an optical filter that passes high wavelengths of light but attenuates (or reduces) wavelengths lower than the cutoff frequency. A long pass filter with a cutoff of 500 nm would pass all wavelengths greater than 500 nm.
http://purl.obolibrary.org/obo/OBI_0400068	LSR2	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A LSR2 is a sorter manufactured by Becton Dickinson. It features digital electronics, a solid state 488 nm blue laser and optionally can also have any combination of solid state UV (355 nm) and violet (405 nm) lasers and the a HeNe (633 nm) ion laser. The LSR2 has the filters and PMTs to work with 13 fluorescent parameters. The LSR II is one of the most common sorters in use.
http://purl.obolibrary.org/obo/OBI_0400069	Luminex 100	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		The Luminex 100 is a flow_cytometer_analyser manufactured by Luminex. It is a single laser system (575 nm) with avalanche photodiodes in red and infrared and a single PMT for fluorescence. The flow chamber is a square quartz cuvette.
http://purl.obolibrary.org/obo/OBI_0400070	Luminex 200	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A Luminex_200 is a flow_cytometer_analyser manufactured by Luminex. The optical specifications are: Reporter laser: 532 nm, nominal output 10 - 15 mW, maximum 500 mW, frequency-doubled diode; mode of operation, continuous wave (CW). Classification laser: 635 nm, 9.1 __ 6%, maximum output 25 mW, diode; mode of operation, continuous wave (CW) Reporter detector: Photomultiplier tube, detection bandwidth of 565 - 585 nm Classification detector and doublet discriminator: Avalanche photo diodes with temperature compensation
http://purl.obolibrary.org/obo/OBI_0400071	MACS Quant	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A MACS Quant is a flow_cytometer_analyser manufactured by Miltenyi. It uses digital electronics, and has three lasers of wavelengths 405 nm, 488 nm, and 635 nm. It has filters and detectors to collect 7 fluorescent parameters and 2 scatter parameters. The MACS Quant is an analyser usually used in research applications.
http://purl.obolibrary.org/obo/OBI_0400073	metal vapor laser	http://purl.obolibrary.org/obo/OBI_0400047	gas laser		A metal vapor laser is a gas laser in which the lasing medium is metal vapor. A metal vapor laser can by used to irradiate cells in a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0400074	mixed argon-krypton gas laser	http://purl.obolibrary.org/obo/OBI_0400060	ion laser		A mixed argon krypton gas laser is an ion laser in which the lasing medium is a mixture of argon and krypton. A mixed argon-krypton laser can by used to irradiate cells in a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0400075	MoFlo	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A MoFlo is a flow_cytometer_sorter manufactured by Dako Cytomation. It features digital electronics, the option to include several lasers (solid state 488 nm, 635 nm, and a 351 nm diode laser), and has the filtering and collection capacity for up to 10 flouresecent parameters. The MoFlo is an instrument that can be used to both analyze quantitatively and collect cells in a flowing medium.
http://purl.obolibrary.org/obo/OBI_0400076	multi-well plate	http://purl.obolibrary.org/obo/OBI_0400081	particle delivery vessel		A particle deliver vessel. A multi-well plate is a vessel that can deliver multiple samples to a flow cytometer in a specified order. It must be used with a plate loader.
http://purl.obolibrary.org/obo/OBI_0400077	neodymium-YAG laser	http://purl.obolibrary.org/obo/OBI_0400096	solid state laser		A Neodymium-YAG (yttrium aluminum garnet) laser is a solid state laser in which the lasing medium is a solid rod of crystalline material pumped by a flash lamp or a diode laser. Typical output wavelengths are 355, 532, and 1064 nm. A neodymium-YAG laser can by used to irradiate cells in a flow cytometer.
http://purl.obolibrary.org/obo/OBI_0400078	obscuration bar	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		An obscuration bar is a an optical subsystem which is a strip of metal or other material that serves to block out direct light from the illuminating beam. The obscuration bar prevents the bright light scattered in the forward directions from burning out the collection device.
http://purl.obolibrary.org/obo/OBI_0400079	optical filter	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		An optical filter is an optical subsystem that selectively transmits light having certain properties (often, a particular range of wavelengths, that is, range of colours of light), while blocking the remainder. They are commonly used in photography, in many optical instruments, and to colour stage lighting Optical filters can be arranged to segregate and collect light by wave length.
http://purl.obolibrary.org/obo/OBI_0400080	optical subsystem	http://purl.obolibrary.org/obo/OBI_0000968	device		A device or part of a device that deals with the behavior and properties of light and the interaction of light with matter. Commonly optical subsystems consist of an excitation optics and collection optics. The excitation optics of a flow cytometer optical subsystem consist of the laser and lenses that are used to shape and focus the laser beam. The collections optics consist of a collection lens to collect light emitted from the particle laser beam interaction and a system of optical mirrors and filters to route specified wavelengths of the collected light to designated optical detectors. The optical subsystem in a flow cytometer consists of the equipment used to irradiate particles, and collect the light either emitted or scattered by those particles.
http://purl.obolibrary.org/obo/OBI_0400081	particle delivery vessel	http://purl.obolibrary.org/obo/OBI_0000047	processed material		Part of the fluidics subsystem. A particle delivery vessel is used to introduce either a single sample or multiple samples to a flow cytometer. The most common particle delivery vessel is a sample tube.
http://purl.obolibrary.org/obo/OBI_0400082	photodetector	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A photodetector is a device used to detect and measure the intensity of radiant energy through photoelectric action. In a cytometer, photodetectors measure either the number of photons of laser light scattered on impact with a cell (for example), or the flourescence emitted by excitation of a fluorescent dye.
http://purl.obolibrary.org/obo/OBI_0400083	photodiode	http://purl.obolibrary.org/obo/OBI_0400082	photodetector		A photodiode is a semiconductor photodetector used to detect light and generate an electrical current. Typically used in forward scatter (FSC) detection. The photodiode collects the forward light scatter in a cytometer.
http://purl.obolibrary.org/obo/OBI_0400084	photomultiplier tube	http://purl.obolibrary.org/obo/OBI_0000967	container		A photomultiplier is a device that is normally in the form of a tube, that uses a photocathode to convert photons into photoelectrons which are then amplified. PMTs are typically used to detect SSC and fluorescent parameters. Cytometers have a PMT for each color they can collect.
http://purl.obolibrary.org/obo/OBI_0400085	piezo electric crystal	http://purl.obolibrary.org/obo/OBI_0000047	processed material		Apparatus in the fluidic subsystem of sorters that vibrates to break up the stream coming out of the flow chamber into droplets for sorting. The peizo electric crystal vibrates in a manner that breaks off droplets at regular intervals. Not all droplets contain a cell.
http://purl.obolibrary.org/obo/OBI_0400086	plate loader	http://purl.obolibrary.org/obo/OBI_0000968	device		Part of the fluidics system. A plate loader positions the wells of a multi-well plate under the aspiration tube is a preset order. A plate loader is used for high throughput applications.
http://purl.obolibrary.org/obo/OBI_0400087	preamplifier	http://purl.obolibrary.org/obo/OBI_0400101	voltage amplifier		A preamplifier is part of the electronics subsystem. It converts the current output from its associated detector to a voltage. The preamplifier is the first stage in analog electronics signal processing.
http://purl.obolibrary.org/obo/OBI_0400088	quartz cuvette flow chamber	http://purl.obolibrary.org/obo/OBI_0400043	flow cell		A flow cell in which the laser irradiates the cell as it passes through a quartz cuvette. A quartz cuvette flow chamber can be used to allow the laser to irradiate cells.
http://purl.obolibrary.org/obo/OBI_0400089	Reflection	http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter		A Reflection is a sorter manufactured by iCyte. It uses digital signal processing, and can be configured with lasers of the users choice from among these excitation wavelengths: 355, 405,488, 532, 635nm. It accommodates up to 48 traditional PMTs. Options include an acousto-optical tunable filter (AOTF) and 16 channel spectrometer (370 to 730 nm). The various detection components can be uniquely configured across multiple Highly Automated Parallel Sorting (HAPS) modules. The Reflection can be used to analyse, sort, and collect cells.
http://purl.obolibrary.org/obo/OBI_0400091	cytometer sample tube	http://purl.obolibrary.org/obo/OBI_0000836	test tube		A particle delivery vessel. The cytometer sample tube is a vessel in which the sample is introduced to the cytometer. Frequently the tube is placed on the cytometer in such a manner that a seal is formed between the tube and cytometer, and gas is used to create enough pressure to push the sample out of the tube and into the cytometer.
http://purl.obolibrary.org/obo/OBI_0400094	sheath tank	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		Part of the fluidics system. The sheath tank is the vessel that holds the sheath fluid at a constant pressure, allowing for it to be pushed into the flow chamber at a constant rate. The sheath tank holds the pressurized sheath fluid.
http://purl.obolibrary.org/obo/OBI_0400095	short pass filter	http://purl.obolibrary.org/obo/OBI_0400079	optical filter		A short pass filter is an optical filter that passes low wavelengths of light but attenuates (or reduces) wavelengths higher than the cutoff frequency. A short pass filter with a cutoff of 500 nm would pass all wavelengths less than 500 nm.
http://purl.obolibrary.org/obo/OBI_0400096	solid state laser	http://purl.obolibrary.org/obo/OBI_0400064	laser		A solid-state laser is a laser that uses a lasing medium that is a solid, rather than a liquid such as dye lasers or a gas such as gas lasers. Semiconductor-based diode lasers are also in the solid state, but are generally considered separately from solid-state lasers. The first laser developed was an optical pumped ruby crystal solid state laser.
http://purl.obolibrary.org/obo/OBI_0400097	Somacount	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		A Somacount is a flow_cytometer_analyser manufactured by Bently Instruments. It is a specialized tool for counting somatic cells in milk by specifically staining them with Ethidium Bromide and counting the cells that fluoresce. It has one laser, and the filters and a PMT for the single parameter. There are three sizes available, the 150, 300, and 500 with the number indicating the maximum number of cells that can be analysed per hour. The Somacount is an example of a very specific use cytometer; it exclusively counts somatic cells in milk.
http://purl.obolibrary.org/obo/OBI_0400098	SomaScope	http://purl.obolibrary.org/obo/OBI_0400008	flow cytometer analyzer		The SomaScope is an instrument to quantify somatic cells in milk.
http://purl.obolibrary.org/obo/OBI_0400099	flow cytometer sorter	http://purl.obolibrary.org/obo/OBI_0400044	flow cytometer		A flow_cytometer_sorter is a flow_cytometer that analyzes and separates or sorts particles passing through (based on properties measured during analysis) to collect cells of interest.
http://purl.obolibrary.org/obo/OBI_0400100	syringe pump	http://purl.obolibrary.org/obo/OBI_0000967	container		Part of the fluidics system. A syringe pump can be used to inject the sample fluid and cells into the sheath fluid in the flow chamber. Syringe pumps are useful for creating stable flow rates.
http://purl.obolibrary.org/obo/OBI_0400101	voltage amplifier	http://purl.obolibrary.org/obo/OBI_0000968	device		A voltage amplifier is a device that amplifies the voltage signal.
http://purl.obolibrary.org/obo/OBI_0400102	waste tank	http://purl.obolibrary.org/obo/OBI_0000967	container		Part of the fluidics systems. In analyzers the sheath and sample fluid, once analyzed is dumped into a waste tank. The waste tank is where the fluids passing through the cytometer end up after the analysis is finished.
http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A DNA sequencer is an instrument that determines the order of deoxynucleotides in deoxyribonucleic acid sequences.
http://purl.obolibrary.org/obo/OBI_0400104	array scanner	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		An processed material which acquires images of fluorescence (induced with lasers) from labeled molecules on the surface of the microarray chip
http://purl.obolibrary.org/obo/OBI_0400105	arrayer	http://purl.obolibrary.org/obo/OBI_0000968	device		A device which deposits biological material onto a substrate in a defined pattern.
http://purl.obolibrary.org/obo/OBI_0400106	centrifuge	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A device with a rapidly rotating container that applies centrifugal force to its contents
http://purl.obolibrary.org/obo/OBI_0400107	computer	http://purl.obolibrary.org/obo/OBI_0000968	device		A computer is an instrument which manipulates (stores, retrieves, and processes) data according to a list of instructions.
http://purl.obolibrary.org/obo/OBI_0400108	heating block	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A heating block is an instrument or part of an instrument which raises or maintains the temperature of a sample to a defined constant temperature during certain parts of an assay
http://purl.obolibrary.org/obo/OBI_0400109	homogenizer	http://purl.obolibrary.org/obo/OBI_0001033	perturbation device		A homogenizer is an instrument for the homogenization of various types of material, such as tissue, plant, food, soil, and many others.
http://purl.obolibrary.org/obo/OBI_0400110	hybridization chamber	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		A device which is used to maintain constant contact of a liquid on an array.  This can be either a glass vial or slide.
http://purl.obolibrary.org/obo/OBI_0400111	hybridization station	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device which is used to maintain the temperature of one or more hybridization_chamber(s) at a defined, constant temperature.
http://purl.obolibrary.org/obo/OBI_0400113	oligonucleotide synthesizer	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		An instrument used to chemically synthesize oligonucleotides.
http://purl.obolibrary.org/obo/OBI_0400114	sonicator	http://purl.obolibrary.org/obo/OBI_0001033	perturbation device		A device that converts a variable electrical current to mechanical vibration of a metallic probe. The device is used for the lysis of cells, the mixing of compounds or solutions, to framgent molecules of DNA, or to create emulsions.
http://purl.obolibrary.org/obo/OBI_0400115	spectrophotometer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A spectrophotometer is an instrument that measures the intensity of light as a function of the color, or more specifically, the wavelength of light, transmitted by a substance.
http://purl.obolibrary.org/obo/OBI_0400117	vacuum dryer	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		An instrument which removes liquid by the application of negative pressure,  i.e. vacuum.
http://purl.obolibrary.org/obo/OBI_0400119	microarray wash station	http://purl.obolibrary.org/obo/OBI_0001034	environmental control device		A device that is used to wash Affymetrix-type arrays.
http://purl.obolibrary.org/obo/OBI_0400120	temperature control bath	http://purl.obolibrary.org/obo/OBI_0002089	container with environmental control		A temperature_control_bath is a device that has the function to regulate the temperature of a material, the function to contain fluid and the function to vary and maintain the temperature of the contained fluid. Heat exchange (energy transfer) between the material and the heating element is facilitated via the contained fluid. A temperature_control_bath is composed of a container, a heating element and/or a cooling element and a means to adjust the needed temperature. In most cases also a timer and a means to stir the fluid is provided as well.
http://purl.obolibrary.org/obo/OBI_0400135	image cytometer	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		An image_cytometer is an instrument for image-based study or measurement of cells.
http://purl.obolibrary.org/obo/OBI_0400137	cytometer	http://purl.obolibrary.org/obo/OBI_0000832	measurement device		A cytometer is an instrument for counting and/or measuring characteristics of cells.
http://purl.obolibrary.org/obo/OBI_0400143	fluorometer	http://purl.obolibrary.org/obo/OBI_0400115	spectrophotometer		A fluorometer is an instrument for the detection and measurement of parameters of fluoresence, which in turn are used to identify the presence and amount of specific molecules in the sample.
http://purl.obolibrary.org/obo/OBI_0400147	microarray	http://purl.obolibrary.org/obo/OBI_0001865	assay array		A processed material that is made to be used in an analyte assay. It consists of a physical immobilisation matrix in which substances that bind the analyte are placed in regular spatial position.
http://purl.obolibrary.org/obo/OBI_0400149	protein microarray	http://purl.obolibrary.org/obo/OBI_0400147	microarray		A protein-microarray is a microarray, ususlly a piece of glass, on which different molecules of protein have been affixed at separate locations in an ordered manner. These are used to identify protein-protein or protein-small molecule interactions.
http://purl.obolibrary.org/obo/OBI_0400153	droplet sorter	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A droplet sorter is part_of a flow cytometer sorter that converts the carrier fluid stream into individual droplets, and these droplets are directed into separate locations for recovery (enriching the original sample for particles of interest based on qualities determined by gating) or disposal.
http://purl.obolibrary.org/obo/OBI_0400155	water bath	http://purl.obolibrary.org/obo/OBI_0400120	temperature control bath		A water bath is a temperature control bath in which a water acts as contact medium enabling temperature transfer from the heating element or cooling element to the sample. The temperature can be controlled in the 0 to 100 degree centigrade range (under normal pressure).
http://purl.obolibrary.org/obo/OBI_0400157	oil bath	http://purl.obolibrary.org/obo/OBI_0400120	temperature control bath		An oil bath is a temperature control bath in which oil acts as contact medium for the temperature transfer (from heating or cooling elements to the sample).
http://purl.obolibrary.org/obo/OBI_0400158	digital-to-analog converter	http://purl.obolibrary.org/obo/OBI_0000968	device		A digital-to-analog_converter is an instrument that converts a finite resolution digital signal into an infinite resolution analog signal.
http://purl.obolibrary.org/obo/OBI_0400168	microtome	http://purl.obolibrary.org/obo/OBI_0000932	material separation device		A microtome is a mechanical instrument used to cut biological specimens into very thin segments for further treatment (e.g. ISH) and ultimately microscopic or histologic examination. Most microtomes provide cooling facilities (cryo-microtome) and use a steel blade to cut a slice of defined thickness. Some are automatic, and some are driven by hand.
http://purl.obolibrary.org/obo/OBI_0400169	microscope	http://purl.obolibrary.org/obo/OBI_0000398	image creation device		A microscope is an instrument which magnifies the view on objects (too small to be viewed by the naked eye) under increased resolution. A microscope can be an optical instrument but also and electronic instrument. There are various kind of optical microscopes, e.g confocal microscope, epifluoresence microscope)
http://purl.obolibrary.org/obo/OBI_0400170	microscope slide	http://purl.obolibrary.org/obo/OBI_0000968	device		A microscope slide is a device usually made of glass which is used as a solid matrix for (biological) material deposited on its surface and which is compatible for use with a microscope instrument
http://purl.obolibrary.org/obo/OBI_0500001	clinical study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		Plan for the precise procedure to be followed in a clinical trial, including planned and actual timing of events, choice of control group, method of allocating treatments, blinding methods; assigns a subject to pass through one or more epochs in the course of a trial. Specific design elements, e.g., crossover, parallel; dose-escalation [Modified from Pocock, Clinical Trials: A Practical Approach]
http://purl.obolibrary.org/obo/OBI_0500002	repeated measure design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		a study design which use the same individuals and exposure them to a set of conditions. The effect of order and practice can be confounding factor in such designs
http://purl.obolibrary.org/obo/OBI_0500003	cross over design	http://purl.obolibrary.org/obo/OBI_0500002	repeated measure design		a repeated measure design which ensures that experimental units receive, in sequence, the treatment (or the control), and then, after a specified time interval (aka *wash-out periods*), switch to the control (or treatment). In this design, subjects (patients in human context) serve as their own controls, and randomization may be used to determine the ordering which a subject receives the treatment and control
http://purl.obolibrary.org/obo/OBI_0500004	n-to-1 design	http://purl.obolibrary.org/obo/OBI_0500003	cross over design		N-of-1 design is a cross-over design in which the same patient is repeatedly randomised to receive either the experimental treatment or its control (Senn, 1993).
http://purl.obolibrary.org/obo/OBI_0500005	matched pairs design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A matched pair design is a study design which use groups of individuals associated (hence matched) to each other based on a set of criteria, one member going to one treatment, the other member receiving the other treatment.
http://purl.obolibrary.org/obo/OBI_0500007	randomized complete block design	http://purl.obolibrary.org/obo/OBI_0000115	intervention design		A randomized complete block design is_a study design which assigns randomly treatments to block. The number of units per block equals the number of treatment so each block receives each treatment exactly once (hence the qualifier 'complete'). The design was originally devised from field trials used in agronomy and agriculture. The analysis assumes that there is no interaction between block and treatment. The method was then used in other settings So The randomised complete block design is a design in which the subjects are matched according to a variable which the experimenter wishes to control. The subjects are put into groups (blocks) of the same size as the number of treatments. The members of each block are then randomly assigned to different treatment groups.
http://purl.obolibrary.org/obo/OBI_0500008	balanced incomplete block design	http://purl.obolibrary.org/obo/OBI_0500014	factorial design		balanced incomplete block design is a kind of factorial design where all treatment pairs occur together within a block an equal number ?? times. ??ii' is the number of times treatment i occurs with i'
http://purl.obolibrary.org/obo/OBI_0500009	loop design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A loop experiment design is where labeled extracts are compared in consecutive pairs. synonym: circular design
http://purl.obolibrary.org/obo/OBI_0500010	reference design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A reference experiment design type is where all samples are compared to a common reference.
http://purl.obolibrary.org/obo/OBI_0500011	latin square design	http://purl.obolibrary.org/obo/OBI_0500007	randomized complete block design		Latin square design is_a study design which allows in its simpler form controlling 2 levels of nuisance variables (also known as blocking variables).he 2 nuisance factors are divided into a tabular grid with the property that each row and each column receive each treatment exactly once.
http://purl.obolibrary.org/obo/OBI_0500012	graeco latin square design	http://purl.obolibrary.org/obo/OBI_0500007	randomized complete block design		Greco-Latin square design is a study design which relates to Latin square design
http://purl.obolibrary.org/obo/OBI_0500013	hyper graeco latin square design	http://purl.obolibrary.org/obo/OBI_0500007	randomized complete block design		PRS to do
http://purl.obolibrary.org/obo/OBI_0500014	factorial design	http://purl.obolibrary.org/obo/OBI_0500000	study design		factorial design is_a study design which is used to evaluate two or more factors simultaneously. The treatments are combinations of levels of the factors. The advantages of factorial designs over one-factor-at-a-time experiments is that they are more efficient and they allow interactions to be detected. In statistics, a factorial design experiment is an experiment whose design consists of two or more factors, each with discrete possible values or levels, and whose experimental units take on all possible combinations of these levels across all such factors. Such an experiment allows studying the effect of each factor on the response variable, as well as the effects of interactions between factors on the response variable.
http://purl.obolibrary.org/obo/OBI_0500015	2x2 factorial design	http://purl.obolibrary.org/obo/OBI_0500014	factorial design		a factorial design which has 2 experimental factors (aka independent variables) and 2 factor levels per experimental factors
http://purl.obolibrary.org/obo/OBI_0500016	fractional factorial design	http://purl.obolibrary.org/obo/OBI_0500014	factorial design		A fractional factorial design is_a study design in which only an adequately chosen fraction of the treatment combinations required for the complete factorial experiment is selected to be run
http://purl.obolibrary.org/obo/OBI_0500017	dye swap design	http://purl.obolibrary.org/obo/OBI_0500000	study design		An experiment design type where the label orientations are reversed. exact synonym: flip dye, dye flip
http://purl.obolibrary.org/obo/OBI_0500018	replicate design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A replicate experimental design type is where a series of replicates are performed to evaluate reproducibility or as a pilot study to determine the appropriate number of replicates for a subsequent experiments.
http://purl.obolibrary.org/obo/OBI_0500019	self vs self design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that investigates variance and error estimates in the experimental system, and is where the same extract is compared.
http://purl.obolibrary.org/obo/OBI_0500020	time series design	http://purl.obolibrary.org/obo/OBI_0500000	study design		Groups of assays that are related as part of a time series.
http://purl.obolibrary.org/obo/OBI_0500022	stopping rule	http://purl.obolibrary.org/obo/IAO_0000055	rule		a stopping rule (criterion) is_a *rule* which causes a *stopping process* to happen
http://purl.obolibrary.org/obo/OBI_0500023	compliance rule	http://purl.obolibrary.org/obo/IAO_0000055	rule		a compliance rule is a rule which ensures a compliance process occurs
http://purl.obolibrary.org/obo/OBI_0500024	standard compliance rule	http://purl.obolibrary.org/obo/OBI_0500023	compliance rule		a  standard compliance rule is a compliance rule which defines conformity to a representation standard
http://purl.obolibrary.org/obo/OBI_0500025	ethical standard compliance rule	http://purl.obolibrary.org/obo/OBI_0500024	standard compliance rule		an ethical standard compliance rule is_a *compliance rule* which enable a  *ethical compliance process* to occur
http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500026	eligibility criterion		an exclusion criterion (rule) is_a *eligibility criterion*  which defines and states a condition which, if met, makes an entity unsuitable for a given task or participation in a given process. For instance, in a study protocol, exclusion criteria indicate the conditions that prospective subjects SHOULD NOT meet to be eligible for participation in a study
http://purl.obolibrary.org/obo/OBI_0600000	adding substance to cell culture	http://purl.obolibrary.org/obo/OBI_0000274	adding a material entity into a target		is process in which a material substance is added to a cell culture
http://purl.obolibrary.org/obo/OBI_0600004	human subject enrollment	http://purl.obolibrary.org/obo/OBI_0001928	selection		A planned process with the objective to obtain a population of human subjects to participate in an investigation by determining eligibility of subjects and obtaining informed consent.
http://purl.obolibrary.org/obo/OBI_0600005	collecting specimen from organism	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process		a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation
http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo	http://purl.obolibrary.org/obo/OBI_0000274	adding a material entity into a target		A process by which a substance is intentionally given to an organism resulting in exposure of the organism to that substance.
http://purl.obolibrary.org/obo/OBI_0600008	acquisition	http://purl.obolibrary.org/obo/OBI_0001928	selection		A planned process with the objective of gaining possession of an entity.
http://purl.obolibrary.org/obo/OBI_0600009	exposure of material to environment	http://purl.obolibrary.org/obo/OBI_0000011	planned process		a planned process in which an input material is exposed to a defined set of conditions in a controlled environment. The environment is a specified input.
http://purl.obolibrary.org/obo/OBI_0600011	acclimatization	http://purl.obolibrary.org/obo/OBI_0600009	exposure of material to environment		A protocol application in which an object is left in an environment for some period of time, until some qualities of interest are in equilibrium with that environment.
http://purl.obolibrary.org/obo/OBI_0600012	environmental material collection process	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process		environmental_material_collection is an acquisition where an object is taken from an environment and put into a storage container. Roles include, environment, thing collected, container, acquirer.
http://purl.obolibrary.org/obo/OBI_0600014	material component separation	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a material processing in which components of an input material become segregated in space
http://purl.obolibrary.org/obo/OBI_0600017	assay detecting a molecular label	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that detects the presence or a quality of a molecular label which is a proxy for the detection of the molecular target to which the label is attached
http://purl.obolibrary.org/obo/OBI_0600019	non-specific labeling	http://purl.obolibrary.org/obo/OBI_0600038	addition of molecular label		The addition of a reagent labeling the entire input biomaterial enabling future detection of the output biomaterial
http://purl.obolibrary.org/obo/OBI_0600021	cell fixation	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a protocol application to preserve defined  qualities of cells or tissues (sample) which may otherwise change over time
http://purl.obolibrary.org/obo/OBI_0600022	excision	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		the use physical means to remove a portion of a substance from the rest
http://purl.obolibrary.org/obo/OBI_0600023	non specific enzymatic cleavage	http://purl.obolibrary.org/obo/OBI_0000231	enzymatic cleavage		an enzymatic cleavage that uses an enzyme without a strong affinity for specific cleavage sites in the input material
http://purl.obolibrary.org/obo/OBI_0600024	maintaining cell culture	http://purl.obolibrary.org/obo/OBI_0000838	material maintenance		A planned process with the objective to keep cells alive in a defined environment outside of an organism.
http://purl.obolibrary.org/obo/OBI_0600025	substance detection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that detects a specified substance
http://purl.obolibrary.org/obo/OBI_0600026	longitudinal mass measurement assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures the mass of a material at two or more time points
http://purl.obolibrary.org/obo/OBI_0600027	artificially induced cell membrane lysis	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a material transformation to break the membranes of cells, releasing the cells contents; input=>cells; output=>cell_lysate
http://purl.obolibrary.org/obo/OBI_0600028	artificially induced reverse transcription	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a protocol with the objective to transcribe single-stranded RNA into complementary DNA (cDNA)
http://purl.obolibrary.org/obo/OBI_0600029	isolation of cell culture supernatant	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a protocol which results in the separation of supernatant material from a cell culture
http://purl.obolibrary.org/obo/OBI_0600030	experimental disease induction	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a protocol application to induce a specific disease in an organism
http://purl.obolibrary.org/obo/OBI_0600032	artificially induced DNA repair	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a protocol application to repair damaged DNA molecules
http://purl.obolibrary.org/obo/OBI_0600033	cell permeabilization	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A protocol application to permeabilize cell membranes, allowing molecules to more easily pass through the membrane than was possible prior to the protocol application
http://purl.obolibrary.org/obo/OBI_0600034	precipitation	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a protocol application to cause a material to precipitate (becoming a solid) out of solution. Input is a solution, output is a solution plus a solid component (the precipitate)
http://purl.obolibrary.org/obo/OBI_0600036	establishing cell culture	http://purl.obolibrary.org/obo/OBI_0000094	material processing		a process through which a new type of cell culture or cell line is created, either through the isolation and culture of one or more cells from a fresh source, or the deliberate experimental modification of an existing cell culture (e.g passaging a primary culture to become a secondary culture or line, or the immortalization or stable genetic modification of an existing culture or line).
http://purl.obolibrary.org/obo/OBI_0600039	artificially induced methylation	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A planned process of adding methyl groups to polymers
http://purl.obolibrary.org/obo/OBI_0600041	concentrate	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a protocol application to create an output material with an increased density of a material of interest that is part of the input material by separating other parts of the input material
http://purl.obolibrary.org/obo/OBI_0600042	recombinant plasmid cloning	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		the insertion of a particular DNA fragment into a plasmid in order to make copies of a biomaterial
http://purl.obolibrary.org/obo/OBI_0600044	lavage	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		A protocol application to separate cells and/or cellular secretions from an anatomical space by the introduction and removal of fluid
http://purl.obolibrary.org/obo/OBI_0600045	3D structure determination assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that determines the 3-dimensional configuration of an input material.
http://purl.obolibrary.org/obo/OBI_0600046	preparative chromatography	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		the use of a biomaterial's preferential affinity for either the mobile phase or the stationary phase to separate it from other materials of differing affinity
http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay the uses chemical or biochemical means to infer the sequence of a biomaterial
http://purl.obolibrary.org/obo/OBI_0600048	vector mediated amplification	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		The process of creating a copy of some biological entity in cell culture
http://purl.obolibrary.org/obo/OBI_0600049	DNA polymerase amplification	http://purl.obolibrary.org/obo/OBI_0600058	enzymatic amplification		DNA polymerase amplification is an enzymatic amplification which uses DNA polymerase enzyme to make copies of a DNA contained in biomaterial used as input
http://purl.obolibrary.org/obo/OBI_0600050	specific enzymatic cleavage	http://purl.obolibrary.org/obo/OBI_0000231	enzymatic cleavage		an enzymatic cleavage that uses an enzyme with a strong affinity for specific cleavage sites in the input material
http://purl.obolibrary.org/obo/OBI_0600051	gradient separation	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a protocol application that uses different concentrations of materials in a defined order to create a gradient to facilitate the separation of an input material into its components with specific qualities
http://purl.obolibrary.org/obo/OBI_0600052	dialysis	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a protocol application that uses diffusion through a semi-permeable membrane to separate an input material into two fractions of different composition
http://purl.obolibrary.org/obo/OBI_0600053	electrophoresis	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		a protocol application that uses an electrical potential to move material through a defined matrix in order to separate it by its resistance to movement and its charge
http://purl.obolibrary.org/obo/OBI_0600054	selection by survival	http://purl.obolibrary.org/obo/OBI_0000094	material processing		the use of environmental conditions to select for the organism or cells that have a certain trait
http://purl.obolibrary.org/obo/OBI_0600056	protease cleavage	http://purl.obolibrary.org/obo/OBI_0000231	enzymatic cleavage		protease cleavage is an enzymatic cleavage which relies on enzyme with protease activity to act on proteins and produce polypeptides (protein fragments).
http://purl.obolibrary.org/obo/OBI_0600057	enzymatic DNA replication	http://purl.obolibrary.org/obo/OBI_0600058	enzymatic amplification		the use of enzymes to duplicate DNA molecule any process used to make additional copies of a biomaterial
http://purl.obolibrary.org/obo/OBI_0600058	enzymatic amplification	http://purl.obolibrary.org/obo/OBI_0000094	material processing		the use of enzymes to increase the number of molecules of a biomaterial
http://purl.obolibrary.org/obo/OBI_0600059	DNA transduction	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation		a genetic transformation which relies on the use of lysogenic infection to transfer DNA sequences into an organism
http://purl.obolibrary.org/obo/OBI_0600060	DNA transfection	http://purl.obolibrary.org/obo/OBI_0001152	transfection		a transfection which relies on the use of physical, electrical and chemical phenomena to introduce DNA into a cell
http://purl.obolibrary.org/obo/OBI_0600063	vector mediated expression	http://purl.obolibrary.org/obo/OBI_0600064	recombinant vector cloning		vector mediated expression sis the generation of copies of biomaterial by in a cell_culture modified for this purpose by insertion of an expression vector
http://purl.obolibrary.org/obo/OBI_0600065	obsolete_defined processes	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		Place holder class, see editor note
http://purl.obolibrary.org/obo/OBI_0600067	specific labeling	http://purl.obolibrary.org/obo/OBI_0600038	addition of molecular label		a labeling in which the labeling reagent used  has a specificity to bind only certain components of the input material
http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction	http://purl.obolibrary.org/obo/OBI_0666667	nucleic acid extraction		A RNA extraction is a nucleic acid extraction where the desired output material is RNA
http://purl.obolibrary.org/obo/OBI_0666667	nucleic acid extraction	http://purl.obolibrary.org/obo/OBI_0302884	extraction		a material separation to recover the nucleic acid fraction of an input material
http://purl.obolibrary.org/obo/OBI_1000023	cell culture supernatant	http://purl.obolibrary.org/obo/OBI_0000047	processed material		Supernatant of a cell culture is a material entity which contains media, supplements, and secreted products of the cells and becomes the environment of cultivated cell.
http://purl.obolibrary.org/obo/OBI_1000024	cell pellet	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A material entity which results from the aggregation of cells produced by the application of centrifugal force to a liquid containing cells in suspension
http://purl.obolibrary.org/obo/OBI_1000042	peptide construct	http://purl.obolibrary.org/obo/OBI_0000047	processed material		a material entity synthesized to contain a number of peptides conjugated together in a non-linear fashion
http://purl.obolibrary.org/obo/OBI_1000048	transgenic organism	http://purl.obolibrary.org/obo/OBI_0302859	genetically modified organism		a transgenic organism is material entity which derives from an organism which has been modified to express a gene not normally part of it
http://purl.obolibrary.org/obo/OBI_1110001	epitope	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity with the disposition to be bound by an adaptive immune receptor.
http://purl.obolibrary.org/obo/OBI_1110002	obsolete_occurrence of disease	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		An occurrence of disease is a process involving pathologic changes within an organism
http://purl.obolibrary.org/obo/OBI_1110003	host exposure to infectious agent	http://purl.obolibrary.org/obo/GO_0008150	biological process		a process in which an infectious agent comes into physical contact with a host organism.
http://purl.obolibrary.org/obo/OBI_1110007	administration in vivo with infectious agent	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		is an administration of an infectious agent to a host organism
http://purl.obolibrary.org/obo/OBI_1110008	occurrence of infectious disease	http://purl.obolibrary.org/obo/OGMS_0000063	disease course		Is an occurrence of a disease caused by an infection
http://purl.obolibrary.org/obo/OBI_1110011	allergic reaction	http://purl.obolibrary.org/obo/OBI_1110122	pathologic process		an allergic reaction is an pathologic immune response by an organism to a non-self entity that is normally harmless(the allergen)
http://purl.obolibrary.org/obo/OBI_1110012	occurrence of allergy	http://purl.obolibrary.org/obo/OGMS_0000063	disease course		The process of an allergic disease occurring in an organism.
http://purl.obolibrary.org/obo/OBI_1110013	ELISPOT assay measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110014	epitope binding by adaptive immune receptor	http://purl.obolibrary.org/obo/GO_0008150	biological process		is the process in which an adaptive immune receptor binds to a material entity (realizing its disposition). The binding affinity is significant enough to trigger an immune response. Specifically, transient non-specific binding of adaptive immune receptors occurring during immune surveillance is not considered significant binding.
http://purl.obolibrary.org/obo/OBI_1110015	Immunization in vivo	http://purl.obolibrary.org/obo/OBI_1110094	immunization		Process of administering an object playing the role of immunogen to a living organism
http://purl.obolibrary.org/obo/OBI_1110016	adaptive immune effector function	http://purl.obolibrary.org/obo/BFO_0000034	function		A function realized as an immune response, which inheres in a T cell, B cell or antibody which derives from or is produced by a cell with prior antigen experience.
http://purl.obolibrary.org/obo/OBI_1110017	living with infected household contact	http://purl.obolibrary.org/obo/OBI_1110111	environmental proximity to infectious agent		a process in which a a human being lives in the same household as another human being that is known to be infected with an infectious agent
http://purl.obolibrary.org/obo/OBI_1110018	living in endemic area	http://purl.obolibrary.org/obo/OBI_1110111	environmental proximity to infectious agent		a process in which a potential host organism lives in a geographic area in which an infectious agent is present to such a degree of frequency that contact is likely
http://purl.obolibrary.org/obo/OBI_1110019	pathogen release in laboratory accident	http://purl.obolibrary.org/obo/OBI_1110111	environmental proximity to infectious agent		a process in which a an infectious agent maintained in a laboratory setting is not contained as planned, leading to potential exposure of human beings to the agent
http://purl.obolibrary.org/obo/OBI_1110020	Immunization in vitro	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A planned process with the objective to administer an object playing the role of immunogen to a cell culture.
http://purl.obolibrary.org/obo/OBI_1110021	infection process	http://purl.obolibrary.org/obo/OBI_1110122	pathologic process		the detrimental process in which an infectious agent colonizes or replicates in a host environment
http://purl.obolibrary.org/obo/OBI_1110022	adaptive immune receptor	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		is a receptor produced by cells of the adaptive immune system with the purpose of binding epitopes.
http://purl.obolibrary.org/obo/OBI_1110023	immunogen	http://purl.obolibrary.org/obo/BFO_0000040	material entity		a material entity bearing the immunogen role
http://purl.obolibrary.org/obo/OBI_1110024	environmental exposure to infectious agent	http://purl.obolibrary.org/obo/GO_0008150	biological process		Is a process in which an infectious agent is in direct contact with a potential host organism in its habitat. This is preceded by proximity to the infectious agent
http://purl.obolibrary.org/obo/OBI_1110026	host of immune response	http://purl.obolibrary.org/obo/OBI_0100026	organism		An organism in which an immune response process occurs.
http://purl.obolibrary.org/obo/OBI_1110028	293-T cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from human embryonic kidney cells. This cell line contains the SV40 Large T-antigen, allowing episomal replication of transfected plasmids containing the SV40 origin of replication.
http://purl.obolibrary.org/obo/OBI_1110029	C1R cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from human B cells. This cell line was created by EBV transformation (B-lymphoblastoid cell-line (BLCL)).
http://purl.obolibrary.org/obo/OBI_1110030	experimental infection of cell culture	http://purl.obolibrary.org/obo/OBI_0600000	adding substance to cell culture		is the administration of an infectious agent to a cell culture with the objective to have the agent colonize and replicate in culture
http://purl.obolibrary.org/obo/OBI_1110031	EL-4 cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from mouse (C57BL/6N) lymphoma cells.
http://purl.obolibrary.org/obo/OBI_1110032	HeLa cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from human cervical cancer cells.
http://purl.obolibrary.org/obo/OBI_1110033	JAWS II cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from mouse dendritic cells.
http://purl.obolibrary.org/obo/OBI_1110034	antigen	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that has the antigen role.
http://purl.obolibrary.org/obo/OBI_1110035	Jurkat cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from human T cells.
http://purl.obolibrary.org/obo/OBI_1110036	JY cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		The JY cell line is an Epstein-Barr virus (EBV)-immortalised b cell lymphoblastoid line.(wikipedia)
http://purl.obolibrary.org/obo/OBI_1110037	assay measuring binding of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_0003128	T cell epitope assay		A T cell epitope assay that measures the binding of T cell receptor to an epitope.
http://purl.obolibrary.org/obo/OBI_1110038	RMA cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from a mouse lymphoma, specifically a Rauscher virus-induced tumor.This cell ine is antigen processing-defective and expresses a very low level of MHC molecules on its surface.
http://purl.obolibrary.org/obo/OBI_1110039	T2 cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A human T-B lymphoblastoid hybrid cell line
http://purl.obolibrary.org/obo/OBI_1110040	infectious disease	http://purl.obolibrary.org/obo/OGMS_0000031	disease		is a disease caused by an infectious agent
http://purl.obolibrary.org/obo/OBI_1110041	lymph node cell specimen	http://purl.obolibrary.org/obo/OBI_0001468	cell specimen		A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types.
http://purl.obolibrary.org/obo/OBI_1110046	organ harvesting	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		The process of removing an organ from its source organism
http://purl.obolibrary.org/obo/OBI_1110049	allergy	http://purl.obolibrary.org/obo/OGMS_0000031	disease		is a disease in which an abnormally strong inflammatory immune response is triggered against non-self entities, and the immune response has no protective effect
http://purl.obolibrary.org/obo/OBI_1110053	cancer	http://purl.obolibrary.org/obo/OGMS_0000031	disease		A disease characterized by abnormal and uncontrolled cell division
http://purl.obolibrary.org/obo/OBI_1110054	autoimmune disease	http://purl.obolibrary.org/obo/OGMS_0000031	disease		Is a disease characterized by an immune response of an organism against parts of itself
http://purl.obolibrary.org/obo/OBI_1110055	obsolete_disease	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		placeholder to be imported from disease ontology
http://purl.obolibrary.org/obo/OBI_1110056	epitope specific IL-2 release by T cells	http://purl.obolibrary.org/obo/GO_0032623	interleukin-2 production		A biological process where T cells produce IL-2 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110057	MHC:epitope complex binding to TCR	http://purl.obolibrary.org/obo/OBI_1110014	epitope binding by adaptive immune receptor		a process of an MHC molecule binding to an entity playing the role of epitope to create an MHC:epitope complex which is then bound by a TCR molecule.
http://purl.obolibrary.org/obo/OBI_1110059	ELISPOT assay measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_1110061	exposure resulting in immune reactivity	http://purl.obolibrary.org/obo/GO_0008150	biological process		a process in which an organism (host) is exposed to some material entity, which results in an immune reactivity
http://purl.obolibrary.org/obo/OBI_1110082	immunogen role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role of a material entity that is realized when the material elicits an immune response targeting itself in whole or in part.
http://purl.obolibrary.org/obo/OBI_1110083	host of immune response role	http://purl.obolibrary.org/obo/BFO_0000023	role		is a role borne by an organism. It is realized by the organism during an immunization or an immune response taking place inside or on the surface of the organism, and in which the responding or stimulated immune system is part of the host.
http://purl.obolibrary.org/obo/OBI_1110084	effector T cell function	http://purl.obolibrary.org/obo/OBI_1110016	adaptive immune effector function		The function inhering in a T cell that is realized in an immune response that results from the T cell receptor binding to the MHC:epitope complex.
http://purl.obolibrary.org/obo/OBI_1110086	restricting MHC role	http://purl.obolibrary.org/obo/BFO_0000023	role		The role played by an MHC molecule by binding a material entity playing the role of epitope when that epitope/MHC molecule pair are recognized (bound) by a TCR molecule on the surface of a cell playing the role of effector cell.
http://purl.obolibrary.org/obo/OBI_1110091	immune epitope carrier role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role inhering in a material entity that is covalently bound to an epitope in order to increase the epitopes immunogenicity.
http://purl.obolibrary.org/obo/OBI_1110093	disposition to infect an organism	http://purl.obolibrary.org/obo/BFO_0000016	disposition		Is a role borne by an agent, and realized when in contact with or inside another organism in which it is capable of replicating and causing disease
http://purl.obolibrary.org/obo/OBI_1110094	immunization	http://purl.obolibrary.org/obo/GO_0008150	biological process		The process of an epitope that is part of or derived from an immunogen coming into contact with adaptive immune cells resulting in these cells acquiring immune effector functions specific for the epitope.
http://purl.obolibrary.org/obo/OBI_1110099	L cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from mouse fibroblasts.
http://purl.obolibrary.org/obo/OBI_1110108	material to be added	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that is added to another material entity in an “adding a material entity into a target” process.
http://purl.obolibrary.org/obo/OBI_1110109	target of material addition	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity that receives the addition of another material entity in an “adding a material entity into a target” process.
http://purl.obolibrary.org/obo/OBI_1110111	environmental proximity to infectious agent	http://purl.obolibrary.org/obo/GO_0008150	biological process		Is a process in which an infectious agent comes close enough to a potential host organism in its habitat that a contact can result
http://purl.obolibrary.org/obo/OBI_1110114	contact to pathogen carrying biological vector	http://purl.obolibrary.org/obo/OBI_1110111	environmental proximity to infectious agent		a process in which a vector carrying an infectious agent comes close enough to a potential host organism that a contact can result
http://purl.obolibrary.org/obo/OBI_1110116	splenocyte specimen	http://purl.obolibrary.org/obo/OBI_0001468	cell specimen		A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types.
http://purl.obolibrary.org/obo/OBI_1110118	P815 cell line	http://purl.obolibrary.org/obo/CLO_0009828	immortal cell line		A cell line derived from mouse mastocytoma.
http://purl.obolibrary.org/obo/OBI_1110120	assay antigen role	http://purl.obolibrary.org/obo/OBI_0000237	antigen role		An antigen role that is realized as part of an assay, where immune recognition of the material with the assay antigen role is being detected as part of the assay.
http://purl.obolibrary.org/obo/OBI_1110122	pathologic process	http://purl.obolibrary.org/obo/GO_0008150	biological process		abnormal, harmful processes caused by or associated with a disease
http://purl.obolibrary.org/obo/OBI_1110124	assay measuring qualitative binding of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_1110037	assay measuring binding of a T cell epitope:MHC:TCR complex		An assay that detects the binding of a MHC:epitope complex with a T cell receptor, and produces a qualitative measurement of the binding as an output.
http://purl.obolibrary.org/obo/OBI_1110125	assay measuring MHC ligand processing and presentation	http://purl.obolibrary.org/obo/OBI_0002075	MHC ligand assay		A MHC ligand assay that determines what ligands are processed and loaded onto MHC molecules by eluting ligands and identifying them.
http://purl.obolibrary.org/obo/OBI_1110126	assay measuring binding of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_0002075	MHC ligand assay		A MHC ligand assay that detects the binding of a ligand to an MHC molecule.
http://purl.obolibrary.org/obo/OBI_1110127	assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0003127	B cell epitope assay		A B cell epitope assay that measures the binding of an antibody receptor to an epitope.
http://purl.obolibrary.org/obo/OBI_1110128	immune epitope assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that detects the binding of an epitope to an adaptive immune receptor, or an immune process resulting from such a binding event, or characterizes the structrue of the complex resulting from such a binding event.
http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding		A T cell epitope assay that detects cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_1110130	assay measuring epitope specific T cell killing	http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding		A T cell epitope dependent biological activity assay that detects the killing of an antigen presenting cell (APC) by a T cell whose TCR recognizes an epitope presented by the APC.
http://purl.obolibrary.org/obo/OBI_1110131	assay measuring epitope specific proliferation of T cells	http://purl.obolibrary.org/obo/OBI_0002055	assay measuring biological activity resulting from T cell epitope:MHC:TCR binding		A T cell epitope dependent biological activity assay that detects T cell proliferation.
http://purl.obolibrary.org/obo/OBI_1110150	51 chromium assay measuring epitope specific T cell killing	http://purl.obolibrary.org/obo/OBI_9999994	chromium release assay		A chromium release assay that detects the killing of an antigen presenting cell (APC) by a T cell whose TCR recognizes an epitope presented by the APC.
http://purl.obolibrary.org/obo/OBI_1110151	ELISA measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001414	assay measuring epitope specific interferon-gamma production by T cells		An enzyme-linked immunosorbent assay that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_1110152	ELISA measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_0001445	assay measuring epitope specific interleukin-2 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110153	ELISA measuring epitope specific interleukin-4 production by T cells	http://purl.obolibrary.org/obo/OBI_0001450	assay measuring epitope specific interleukin-4 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-4 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110154	ELISA measuring epitope specific interleukin-5 production by T cells	http://purl.obolibrary.org/obo/OBI_0001230	assay measuring epitope specific interleukin-5 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-5 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110155	ELISA measuring epitope specific tumor necrosis factor alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001416	assay measuring epitope specific tumor necrosis factor alpha production by T cells		An enzyme-linked immunosorbent assay that detects tumor necrosis factor alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_1110156	ELISA measuring epitope specific interleukin-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0001209	assay measuring epitope specific interleukin-10 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110157	ELISA measuring epitope specific granulocyte macrophage colony-stimulating factor production by T cells	http://purl.obolibrary.org/obo/OBI_0001233	assay measuring epitope specific granulocyte macrophage colony stimulating factor production by T cells		An enzyme-linked immunosorbent assay that detects granulocyte macrophage colony stimulating factor production by T cells.
http://purl.obolibrary.org/obo/OBI_1110158	ELISA measuring epitope specific interleukin-6 production by T cells	http://purl.obolibrary.org/obo/OBI_0001451	assay measuring epitope specific interleukin-6 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-6 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110159	ELISA measuring epitope specific interleukin-13 production by T cells	http://purl.obolibrary.org/obo/OBI_0001251	assay measuring epitope specific interleukin-13 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-13 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110160	ELISA measuring epitope specific interleukin-12 production by T cells	http://purl.obolibrary.org/obo/OBI_0001391	assay measuring epitope specific interleukin-12 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-12 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110161	ELISA measuring epitope specific interleukin-1 beta production by T cells	http://purl.obolibrary.org/obo/OBI_0001449	assay measuring epitope specific interleukin-1 beta production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-1 beta production by T cells.
http://purl.obolibrary.org/obo/OBI_1110162	ELISA measuring epitope specific interleukin-17 production by T cells	http://purl.obolibrary.org/obo/OBI_0001295	assay measuring epitope specific interleukin-17 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-17 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110163	ELISA measuring epitope specific interleukin-18 production by T cells	http://purl.obolibrary.org/obo/OBI_0001380	assay measuring epitope specific interleukin-18 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-18 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110167	ELISPOT assay measuring epitope specific interleukin-4 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-4 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110168	ELISPOT assay measuring epitope specific tumor necrosis factor alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001416	assay measuring epitope specific tumor necrosis factor alpha production by T cells		An enzyme-linked immunospot assay that detects tumor necrosis factor alpha production by T cells
http://purl.obolibrary.org/obo/OBI_1110170	ELISPOT assay measuring epitope specific interleukin-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110171	ELISPOT assay measuring epitope specific interleukin-13 production by T cells	http://purl.obolibrary.org/obo/OBI_0600031	enzyme-linked immunospot assay		An enzyme-linked immunospot assay that detects interleukin-13 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110172	intracellular cytokine staining assay measuring epitope specific interferon-gamma production by T cells	http://purl.obolibrary.org/obo/OBI_0001414	assay measuring epitope specific interferon-gamma production by T cells		A flow cytometry assay that detects interferon-gamma production by T cells.
http://purl.obolibrary.org/obo/OBI_1110173	intracellular cytokine staining assay measuring epitope specific interleukin-2 production by T cells	http://purl.obolibrary.org/obo/OBI_0001445	assay measuring epitope specific interleukin-2 production by T cells		A flow cytometry assay that detects interleukin-2 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110174	intracellular cytokine staining assay measuring epitope specific tumor necrosis factor alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0001416	assay measuring epitope specific tumor necrosis factor alpha production by T cells		A flow cytometry assay that detects tumor necrosis factor alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_1110175	intracellular cytokine staining assay measuring epitope specific interleukin-4 production by T cells	http://purl.obolibrary.org/obo/OBI_0001450	assay measuring epitope specific interleukin-4 production by T cells		A flow cytometry assay that detects interleukin-4 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110177	intracellular cytokine staining assay measuring epitope specific interleukin-10 production by T cells	http://purl.obolibrary.org/obo/OBI_0001209	assay measuring epitope specific interleukin-10 production by T cells		A flow cytometry assay that detects interleukin-10 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110178	intracellular cytokine staining assay measuring epitope specific interleukin-17 production by T cells	http://purl.obolibrary.org/obo/OBI_0001295	assay measuring epitope specific interleukin-17 production by T cells		A flow cytometry assay that detects interleukin-17 production by T cells.
http://purl.obolibrary.org/obo/OBI_1110179	MHC tetramer/multimer assay measuring binding of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_1110124	assay measuring qualitative binding of a T cell epitope:MHC:TCR complex		A MHC tetramer/multimer assay that measures the binding of an epitope:MHC complex binding with a T cell receptor.
http://purl.obolibrary.org/obo/OBI_1110180	3H-thymidine assay measuring epitope specific proliferation of T cells	http://purl.obolibrary.org/obo/OBI_0002071	in vitro assay measuring epitope specific proliferation of T cells		A tritiated thymidine incorporation assay that detects T cell epitope specific proliferation in vitro.
http://purl.obolibrary.org/obo/OBI_1110181	BrdU assay measuring epitope specific proliferation of T cells	http://purl.obolibrary.org/obo/OBI_0002071	in vitro assay measuring epitope specific proliferation of T cells		A BrdU incorporation assay that detects T cell epitope specific proliferation in vitro.
http://purl.obolibrary.org/obo/OBI_1110182	epitope specific T cell proliferation	http://purl.obolibrary.org/obo/GO_0042098	T cell proliferation		A biological process where T cells proliferate resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110184	epitope specific GM-CSF release by T cells	http://purl.obolibrary.org/obo/GO_0032604	granulocyte macrophage colony-stimulating factor production		A biological process where T cells produce GM-CSF resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110185	epitope specific IFN-g release by T cells	http://purl.obolibrary.org/obo/GO_0032609	type II interferon production		A biological process where T cells produce IFNg resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110187	epitope specific IL-10 release by T cells	http://purl.obolibrary.org/obo/GO_0032613	interleukin-10 production		A biological process where T cells produce IL-10 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110190	epitope specific IL-12 release by T cells	http://purl.obolibrary.org/obo/GO_0032615	interleukin-12 production		A biological process where T cells produce IL-12 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110191	epitope specific IL-13 release by T cells	http://purl.obolibrary.org/obo/GO_0032616	interleukin-13 production		A biological process where T cells produce IL-13 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110193	epitope specific IL-17 release by T cells	http://purl.obolibrary.org/obo/GO_0032620	interleukin-17 production		A biological process where T cells produce IL-17 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110195	epitope specific IL-18 release by T cells	http://purl.obolibrary.org/obo/GO_0032621	interleukin-18 production		A biological process where T cells produce IL-18 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110196	epitope specific IL-1b release by T cells	http://purl.obolibrary.org/obo/GO_0032611	interleukin-1 beta production		A biological process where T cells produce IL-1b resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110199	epitope specific IL-4 release by T cells	http://purl.obolibrary.org/obo/GO_0032633	interleukin-4 production		A biological process where T cells produce IL-4 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110201	allergen	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity bearing the disposition to cause an allergic reaction
http://purl.obolibrary.org/obo/OBI_1110202	epitope specific IL-5 release by T cells	http://purl.obolibrary.org/obo/GO_0032634	interleukin-5 production		A biological process where T cells produce IL-5 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110203	epitope specific IL-6 release by T cells	http://purl.obolibrary.org/obo/GO_0032635	interleukin-6 production		A biological process where T cells produce IL-6 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110204	epitope specific killing by T cells	http://purl.obolibrary.org/obo/GO_0001913	T cell mediated cytotoxicity		A biological process where T cells lyse antigen presenting cells resulting from the recognition of a T cell epitope on MHC molecules of the antigen presenting cell.
http://purl.obolibrary.org/obo/OBI_1110206	epitope specific TNF release by T cells	http://purl.obolibrary.org/obo/GO_0032640	tumor necrosis factor production		A biological process where T cells produce TNF resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_1110300	direct submission to IEDB	http://purl.obolibrary.org/obo/IAO_0000088	report		A report about experiments in an investigation that characterize immune epitopes, and was submitted directly by the authors to the Immune Epitope Database (IEDB)
http://purl.obolibrary.org/obo/OBI_9999994	chromium release assay	http://purl.obolibrary.org/obo/OBI_0000903	in vitro cell killing assay		An in vitro cell killing assay in which radioactive chromium is absorbed by cells and released into supernatant when the cells die. The amount of radioactivity measured in the supernatant is a proxy for the number of cells that have died.
http://purl.obolibrary.org/obo/OGMS_0000015	clinical history	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		A series of statements representing health-relevant qualities of a patient and of a patient's family.
http://purl.obolibrary.org/obo/OGMS_0000023	phenotype	http://purl.obolibrary.org/obo/BFO_0000019	quality		A (combination of) quality(ies) of an organism determined by the interaction of its genetic make-up and environment that differentiates specific instances of a species from other instances of the same species.
http://purl.obolibrary.org/obo/OGMS_0000031	disease	http://purl.obolibrary.org/obo/BFO_0000016	disposition		A disposition (i) to undergo pathological processes that (ii) exists in an organism because of one or more disorders in that organism.
http://purl.obolibrary.org/obo/OGMS_0000063	disease course	http://purl.obolibrary.org/obo/GO_0008150	biological process		The totality of all processes through which a given disease instance is realized.
http://purl.obolibrary.org/obo/OGMS_0000090	treatment	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process whose completion is hypothesized by a health care provider to eliminate, prevent, or alleviate a disorder, the signs and symptoms of a disorder, or a pathological process
http://purl.obolibrary.org/obo/PATO_0000011	age	http://purl.obolibrary.org/obo/PATO_0000165	time		A time quality inhering in a bearer by virtue of how long the bearer has existed.
http://purl.obolibrary.org/obo/PATO_0000018	fluorescence	http://purl.obolibrary.org/obo/PATO_0001296	luminous flux		A luminous flux quality inhering in a bearer by virtue of the bearer's emitting longer wavelength light following the absorption of shorter wavelength radiation; fluorescence is common with aromatic compounds with several rings joined together.
http://purl.obolibrary.org/obo/PATO_0000047	biological sex	http://purl.obolibrary.org/obo/PATO_0001995	organismal quality		An organismal quality inhering in a bearer by virtue of the bearer's ability to undergo sexual reproduction in order to differentiate the individuals or types involved.
http://purl.obolibrary.org/obo/PATO_0000122	length	http://purl.obolibrary.org/obo/PATO_0001708	1-D extent		A 1-D extent quality which is equal to the distance between two points.
http://purl.obolibrary.org/obo/PATO_0000125	mass	http://purl.obolibrary.org/obo/PATO_0001018	physical quality		A physical quality that inheres in a bearer by virtue of the proportion of the bearer's amount of matter.
http://purl.obolibrary.org/obo/PATO_0000146	temperature	http://purl.obolibrary.org/obo/PATO_0001018	physical quality		A physical quality of the thermal energy of a system.
http://purl.obolibrary.org/obo/PATO_0000186	behavioral quality	http://purl.obolibrary.org/obo/PATO_0001995	organismal quality		An organismal quality inhering in a bearer by virtue of the bearer's behavior aggregate of the responses or reactions or movements in a given situation.
http://purl.obolibrary.org/obo/PATO_0000383	female	http://purl.obolibrary.org/obo/PATO_0001894	phenotypic sex		A biological sex quality inhering in an individual or a population that only produces gametes that can be fertilised by male gametes.
http://purl.obolibrary.org/obo/PATO_0000384	male	http://purl.obolibrary.org/obo/PATO_0001894	phenotypic sex		A biological sex quality inhering in an individual or a population whose sex organs contain only male gametes.
http://purl.obolibrary.org/obo/PATO_0000918	volume	http://purl.obolibrary.org/obo/PATO_0001710	3-D extent		A 3-D extent quality inhering in a bearer by virtue of the bearer's amount of 3-dimensional space it occupies.
http://purl.obolibrary.org/obo/PATO_0001025	pressure	http://purl.obolibrary.org/obo/PATO_0001018	physical quality		A physical quality that inheres in a bearer by virtue of the bearer's amount of force per unit area it exerts.
http://purl.obolibrary.org/obo/PATO_0001161	diluted	http://purl.obolibrary.org/obo/PATO_0000033	concentration of		A concentration which relatively low.
http://purl.obolibrary.org/obo/PATO_0001167	damaged	http://purl.obolibrary.org/obo/PATO_0001020	damage		A structural quality inhering in a bearer by virtue of the bearer being harmed or injured or spoiled, such that its functionality is impaired.
http://purl.obolibrary.org/obo/PATO_0001193	lateral to	http://purl.obolibrary.org/obo/PATO_0000140	position		A spatial quality inhering in a bearer by virtue of the bearer's being located toward the side relative to another entity.
http://purl.obolibrary.org/obo/PATO_0001196	ventral to	http://purl.obolibrary.org/obo/PATO_0000140	position		A spatial quality inhering in a bearer by virtue of the bearer's being located toward the abdomen of an organism relative to another entity.
http://purl.obolibrary.org/obo/PATO_0001233	dorsal to	http://purl.obolibrary.org/obo/PATO_0000140	position		A spatial quality inhering in a bearer by virtue of the bearer's being located toward the back or upper surface of an organism relative to another entity.
http://purl.obolibrary.org/obo/PATO_0001338	mixed sex	http://purl.obolibrary.org/obo/PATO_0002003	population quality		A biological sex quality inhering in a population of multiple sexes.
http://purl.obolibrary.org/obo/PATO_0001339	biomaterial purity	http://purl.obolibrary.org/obo/PATO_0000025	composition		A composition quality inhering in an bearer by virtue of the bearer's homogeneity of a biomaterial.
http://purl.obolibrary.org/obo/PATO_0001340	hermaphrodite	http://purl.obolibrary.org/obo/PATO_0001894	phenotypic sex		A biological sex quality inhering in an organism or a population with both male and female sexual organs in one individual.
http://purl.obolibrary.org/obo/PATO_0001341	a mating type (yeast)	http://purl.obolibrary.org/obo/PATO_0001342	Saccharomyces cerevisiae mating type		A S. cerevisiae mating type cells that secrete a pheromone that in alpha haploids stimulates processes that lead to mating.
http://purl.obolibrary.org/obo/PATO_0001344	alpha mating type (yeast)	http://purl.obolibrary.org/obo/PATO_0001342	Saccharomyces cerevisiae mating type		A S. cerevisiae mating type cells that secrete a pheromone that stimulates a haploids.
http://purl.obolibrary.org/obo/PATO_0001345	h minus	http://purl.obolibrary.org/obo/PATO_0001343	Schizosaccharomyces pombe mating type		A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus.
http://purl.obolibrary.org/obo/PATO_0001346	h plus	http://purl.obolibrary.org/obo/PATO_0001343	Schizosaccharomyces pombe mating type		A S. pombe mating type determined by the mat1-Pc and mat1-Pi on the mat1 locus.
http://purl.obolibrary.org/obo/PATO_0001347	F mating type	http://purl.obolibrary.org/obo/PATO_0001335	bacterial mating type		A bacterial mating type indicating the presence of F plasmid in a bacterial cell.
http://purl.obolibrary.org/obo/PATO_0001348	F minus mating type	http://purl.obolibrary.org/obo/PATO_0001335	bacterial mating type		A bacterial mating type indicating the absence of F plasmid in a bacterial cell.
http://purl.obolibrary.org/obo/PATO_0001374	ploidy	http://purl.obolibrary.org/obo/PATO_0001396	cellular quality		A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism.
http://purl.obolibrary.org/obo/PATO_0001375	haploid	http://purl.obolibrary.org/obo/PATO_0001393	euploid		A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes.
http://purl.obolibrary.org/obo/PATO_0001377	polyploid	http://purl.obolibrary.org/obo/PATO_0001393	euploid		A ploidy quality inhering in a bearer by virtue of the bearer's containing more than two homologous sets of chromosomes.
http://purl.obolibrary.org/obo/PATO_0001385	aneuploid	http://purl.obolibrary.org/obo/PATO_0001374	ploidy		A ploidy quality inhering in a bearer by virtue of the bearer's containing a non-integral multiple of the monoploid number, due to extra or missing chromosomes.
http://purl.obolibrary.org/obo/PATO_0001394	diploid	http://purl.obolibrary.org/obo/PATO_0001393	euploid		A ploidy quality inhering in a bearer by virtue of the bearer's having two copies (homologs) of each chromosome, usually one from the mother and one from the father.
http://purl.obolibrary.org/obo/PATO_0001396	cellular quality	http://purl.obolibrary.org/obo/PATO_0070044	anatomical structure quality		A monadic quality of continuant that exists at the cellular level of organisation.
http://purl.obolibrary.org/obo/PATO_0001421	alive	http://purl.obolibrary.org/obo/PATO_0000169	viability		A viability quality inhering in a bearer by virtue of the bearer's condition before death.
http://purl.obolibrary.org/obo/PATO_0001422	dead	http://purl.obolibrary.org/obo/PATO_0000169	viability		A viability quality inhering in a bearer by virtue of the cessation of the bearer's life.
http://purl.obolibrary.org/obo/PATO_0001546	quality of a solid	http://purl.obolibrary.org/obo/PATO_0002198	quality of a substance		A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity characterized by particles arranged such that their shape and volume are relatively stable.
http://purl.obolibrary.org/obo/PATO_0001547	quality of a gas	http://purl.obolibrary.org/obo/PATO_0002198	quality of a substance		A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape.
http://purl.obolibrary.org/obo/PATO_0001548	quality of a liquid	http://purl.obolibrary.org/obo/PATO_0002198	quality of a substance		A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape.
http://purl.obolibrary.org/obo/PATO_0001741	radioactive	http://purl.obolibrary.org/obo/PATO_0001740	activity (of a radionuclide)		A radiation quality inhering in bearer by virtue of the bearer's exhibiting or being caused by radioactivity.
http://purl.obolibrary.org/obo/PATO_0001792	left side of	http://purl.obolibrary.org/obo/PATO_0000140	position		A spatial quality inhering in a bearer by virtue of the bearer's being located on left side of from the a another entity.
http://purl.obolibrary.org/obo/PATO_0001793	right side of	http://purl.obolibrary.org/obo/PATO_0000140	position		A spatial quality inhering in a bearer by virtue of the bearer's being located on right side of a another entity.
http://purl.obolibrary.org/obo/PATO_0001985	frozen	http://purl.obolibrary.org/obo/PATO_0000146	temperature		A quality inhering in a bearer by virtue of the bearer's being kept below its freezing point.
http://purl.obolibrary.org/obo/PATO_0001995	organismal quality	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		A quality that inheres in an entire organism or part of an organism.
http://purl.obolibrary.org/obo/PATO_0002201	handedness	http://purl.obolibrary.org/obo/PATO_0000186	behavioral quality		A behavioral quality inhering ina bearer by virtue of the bearer's unequal distribution of fine motor skill between its left and right hands or feet.
http://purl.obolibrary.org/obo/PATO_0002202	left handedness	http://purl.obolibrary.org/obo/PATO_0002201	handedness		Handedness where the organism preferentially uses the left hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.
http://purl.obolibrary.org/obo/PATO_0002203	right handedness	http://purl.obolibrary.org/obo/PATO_0002201	handedness		Handedness where the organism preferentially uses the right hand or foot for tasks requiring the use of a single hand or foot or a dominant hand or foot.
http://purl.obolibrary.org/obo/PATO_0002204	ambidextrous handedness	http://purl.obolibrary.org/obo/PATO_0002201	handedness		Handedness where the organism exhibits no overall dominance in the use of right or left hand or foot in the performance of tasks that require one hand or foot or a dominant hand or foot.
http://purl.obolibrary.org/obo/PATO_0002243	fluid flow rate	http://purl.obolibrary.org/obo/PATO_0001574	flow rate		A physical quality inhering in a fluid (liquid or gas) by virtue of the amount of fluid which passes through a given surface per unit time.
http://purl.obolibrary.org/obo/PR_000000001	protein	http://purl.obolibrary.org/obo/CHEBI_16670	peptide		An amino acid chain that is canonically produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof.
http://purl.obolibrary.org/obo/PR_000001004	CD4 molecule	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence.
http://purl.obolibrary.org/obo/PR_000001018	CD3 subunit with immunoglobulin domain	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response.
http://purl.obolibrary.org/obo/PR_000003252	antithrombin-III	http://purl.obolibrary.org/obo/PR_000000001	protein		A serpin that is a translation product of the human SERPINC1 gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000003745	double-stranded RNA-specific adenosine deaminase	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human ADAR gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000006592	deoxyribonuclease-1	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human DNASE1 gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000007928	glial cell line-derived neurotrophic factor	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human GDNF gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000014060	ribonuclease T2	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human RNASET2 gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000025402	T cell receptor co-receptor CD8	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein-containing complex that is a membrane-bound heterodimeric co-receptor for MHC class-I antigen/T-cell receptor interaction.
http://purl.obolibrary.org/obo/PR_000025467	guanyl-specific ribonuclease T1	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the Aspergillus oryzae RIB40 rntA gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000025471	nuclease S1	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the Aspergillus oryzae RIB40 nucS gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000025475	ribonuclease U2	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the Ustilago sphaerogena RNU2 gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000025477	ribonuclease V1 (cobra)	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein with ribonuclease activity that is a constituent of cobra venom.
http://purl.obolibrary.org/obo/PR_000025478	ribonuclease CL3 (chicken)	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein with ribonuclease activity that is purified from chicken liver.
http://purl.obolibrary.org/obo/SO_0000148	supercontig	http://purl.obolibrary.org/obo/SO_0000353	sequence_assembly		One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's.
http://purl.obolibrary.org/obo/SO_0000149	contig	http://purl.obolibrary.org/obo/SO_0000353	sequence_assembly		A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases.
http://purl.obolibrary.org/obo/SO_0000276	miRNA	http://purl.obolibrary.org/obo/SO_0000001	region		Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene (or the product of other non coding RNA genes). Micro RNAs are produced from precursor molecules (SO:0001244) that can form local hairpin structures, which ordinarily are processed (usually via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.
http://purl.obolibrary.org/obo/SO_0000353	sequence_assembly	http://purl.obolibrary.org/obo/SO_0001248	assembly		A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences.
http://purl.obolibrary.org/obo/SO_0000988	circular	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		A quality of a nucleotide polymer that has no terminal nucleotide residues.
http://purl.obolibrary.org/obo/SO_0001248	assembly	http://purl.obolibrary.org/obo/SO_0001410	experimental_feature		A region of the genome of known length that is composed by ordering and aligning two or more different regions.
http://purl.obolibrary.org/obo/VO_0000001	vaccine	http://purl.obolibrary.org/obo/BFO_0000040	material entity		Material entity that is manufactured to realize the vaccine function.
http://purl.obolibrary.org/obo/VO_0000002	vaccination	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		A process of administering a vaccine in vivo to a recipient (e.g., human) with the intent to invoke a protective or therapeutic adaptive immune response.
http://purl.obolibrary.org/obo/OMIABIS_0000050	fixed tissue specimen	http://purl.obolibrary.org/obo/OBI_0000953	processed specimen		A processed specimen that is the output of a fixation process.
http://purl.obolibrary.org/obo/OMIABIS_0000052	fixed tissue slide specimen	http://purl.obolibrary.org/obo/OMIABIS_0000050	fixed tissue specimen		A fixed tissue specimen that is placed in a slide.
http://purl.obolibrary.org/obo/CL_0001064	malignant cell	http://purl.obolibrary.org/obo/CL_0000000	cell		A neoplastic cell that is capable of entering a surrounding tissue
http://purl.obolibrary.org/obo/OBI_0003333	computed image data set	http://purl.obolibrary.org/obo/OBI_0003327	image data set		An image data set that is the output of an image data set analysis.
http://purl.obolibrary.org/obo/OBI_0003334	reconstructed magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003328	magnetic resonance image data set		An image data set that is the direct output of a raw magnetic resonance image data set reconstruction or a transformation of another MR image data set.
http://purl.obolibrary.org/obo/OBI_0003354	raw magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003331	raw image data set		An image data set that is the direct output of an magnetic resonance imaging assay and whose values encode spatial frequencies produced by the NMR or MRI instrument.
http://purl.obolibrary.org/obo/OBI_0003356	raw magnetic resonance image data set reconstruction	http://purl.obolibrary.org/obo/OBI_0003355	image data set analysis		A process that transforms raw magnetic resonance image data from an NMR/MRI machine into a reconstructed magnetic resonance image data set.
http://purl.obolibrary.org/obo/OBI_0003548	upper limit of detection	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that specifies the largest concentration/amount of a substance that can be quantified in an analyte assay.
http://purl.obolibrary.org/obo/OBI_0003549	lower limit of detection	http://purl.obolibrary.org/obo/OBI_0001933	value specification		A value specification that specifies the smallest concentration/amount of a substance that can be detected in an analyte assay.
http://purl.obolibrary.org/obo/OBI_0003576	skin of body microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a skin of body specimen.
http://purl.obolibrary.org/obo/OBI_0003577	skin of body microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a skin of body microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003578	bone marrow microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a bone marrow specimen.
http://purl.obolibrary.org/obo/OBI_0003579	bone marrow microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a bone marrow microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003580	nasal aspirate microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a nasal aspirate specimen.
http://purl.obolibrary.org/obo/OBI_0003581	nasal aspirate microbiology datum	http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum		An organism detection datum that is the specified output of a nasal aspirate microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003582	cell proliferation assay using carboxyfluorescein succinimidyl ester staining	http://purl.obolibrary.org/obo/OBI_0002106	carboxyfluorescein succinimidyl ester staining assay		A cell proliferation assay that uses carboxyfluorescein succinimidyl ester staining to detect cell division.
http://purl.obolibrary.org/obo/OBI_0003583	cell viability assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay which measures the number of living cells in a population.
http://purl.obolibrary.org/obo/OBI_0003584	cell viability assay using Annexin V staining	http://purl.obolibrary.org/obo/OBI_0003583	cell viability assay		A cell viability assay that uses Annexin V staining to detect apoptotic cells.
http://purl.obolibrary.org/obo/OBI_0003585	carboxyfluorescein succinimidyl ester staining	http://purl.obolibrary.org/obo/OBI_0302887	staining		Staining using carboxyfluorescein succinimidyl ester.
http://purl.obolibrary.org/obo/OBI_0003586	Annexin V staining	http://purl.obolibrary.org/obo/OBI_0302887	staining		Staining using Annexin V to detect apoptotic cells.
http://purl.obolibrary.org/obo/OBI_0003631	antibody purification of H2-Ld protein complex, H2-Db protein complex, and/or H2-Dq protein complex	http://purl.obolibrary.org/obo/OBI_0003627	antibody purification of mouse MHC class I protein complex		An antibody purification of mouse MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of H2-Ld protein complex, H2-Db protein complex, and/or H2-Dq protein complex while others contain impurities and are not of interest.
http://purl.obolibrary.org/obo/OBI_0003694	longitudinal investigation	http://purl.obolibrary.org/obo/OBI_0000066	investigation		An investigation that involves repeated observations of the same variables (e.g., people) over long periods of time.
http://purl.obolibrary.org/obo/OBI_0003700	phase I clinical trial	http://purl.obolibrary.org/obo/OBI_0003699	clinical trial		A clinical trial that produces information about the safety of a drug and the adverse events associated with that drug, and which is typically conducted with healthy participants.
http://purl.obolibrary.org/obo/OBI_0003738	blood type assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that classifies an organism's blood within one or more blood group classification systems by identifying antigens present in the blood.
http://purl.obolibrary.org/obo/CHEBI_17709	5'-adenylyl sulfate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An adenosine 5'-phosphate having a sulfo group attached to one the phosphate OH groups.
http://purl.obolibrary.org/obo/CHEBI_15956	biotin	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins.
http://purl.obolibrary.org/obo/CHEBI_16134	ammonia	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms.
http://purl.obolibrary.org/obo/CHEBI_16247	phospholipid	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides.
http://purl.obolibrary.org/obo/CHEBI_16301	nitrite	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		The nitrogen oxoanion formed by loss of a proton from nitrous acid.
http://purl.obolibrary.org/obo/CHEBI_16737	creatinine	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A lactam obtained by formal cyclocondensation of creatine. It is a metabolite of creatine.
http://purl.obolibrary.org/obo/CHEBI_16919	creatine	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A glycine derivative having methyl and amidino groups attached to the nitrogen.
http://purl.obolibrary.org/obo/CHEBI_16990	bilirubin IXalpha	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A member of the class of  biladienes that is a linear tetrapyrrole with the dipyrrole units being of both exovinyl and endovinyl type. A product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin.
http://purl.obolibrary.org/obo/CHEBI_16991	deoxyribonucleic acid	http://purl.obolibrary.org/obo/CHEBI_33696	nucleic acid		High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms.
http://purl.obolibrary.org/obo/CHEBI_17026	progesterone	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species.
http://purl.obolibrary.org/obo/CHEBI_17230	homocysteine	http://purl.obolibrary.org/obo/CHEBI_33709	amino acid		A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain.
http://purl.obolibrary.org/obo/CHEBI_17234	glucose	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An aldohexose used as a source of energy and metabolic intermediate.
http://purl.obolibrary.org/obo/CHEBI_17423	methemoglobin	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		A hemoprotein that is the ferric (Fe(3+)) form of hemoglobin.
http://purl.obolibrary.org/obo/CHEBI_17544	hydrogencarbonate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		The carbon oxoanion resulting from the removal of a proton from carbonic acid.
http://purl.obolibrary.org/obo/CHEBI_17650	cortisol	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses.
http://purl.obolibrary.org/obo/CHEBI_28358	rac-lactic acid	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A racemate comprising equimolar amounts of (R)- and (S)-lactic acid.
http://purl.obolibrary.org/obo/CHEBI_33696	nucleic acid	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid.
http://purl.obolibrary.org/obo/CHEBI_33709	amino acid	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A carboxylic acid containing one or more amino groups.
http://purl.obolibrary.org/obo/CHEBI_29237	deuterium atom	http://purl.obolibrary.org/obo/CHEBI_33250	atom		The stable isotope of hydrogen with relative atomic mass 2.014102 and a natural abundance of 0.0115 atom percent (from Greek deltaepsilonupsilontauepsilonrhoomicronnu, second).
http://purl.obolibrary.org/obo/CHEBI_42191	EDTA(4-)	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A tetracarboxylic acid anion formed by deprotonation of all four carboxy groups in ethylenediaminetetraacetic acid (EDTA).
http://purl.obolibrary.org/obo/CHEBI_4551	digoxin	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A  cardenolide glycoside that is digitoxin beta-hydroxylated at C-12. A cardiac glycoside extracted from the foxglove plant, Digitalis lanata, it is used to control ventricular rate in atrial fibrillation and in the management of congestive heart failure with atrial fibrillation, but the margin between toxic and therapeutic doses is small.
http://purl.obolibrary.org/obo/CHEBI_59052	1,1-dihydroxy-3-ethoxy-2-butanone	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A butanone derivative having two hydroxy substituents at the 1-position and an ethoxy substituent at the 3-position.
http://purl.obolibrary.org/obo/CHEBI_59053	N-cyclohexyl-N'-(2-(4-morpholinyl)ethyl)carbodiimide	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A carbodiimide having cyclcohexyl and 2-(4-morpholinyl)ethyl as the two N-substituents.
http://purl.obolibrary.org/obo/CHEBI_59054	N-methylisatoic anhydride	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A 3,1-benzoxazin-1,4-dione having an N-methyl substituent.
http://purl.obolibrary.org/obo/CHEBI_59055	(S)-1-(4-bromoacetamidobenzyl)EDTA	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A tetracarboxylic acid consisting of ethylenediaminetetraacetic acid having a 4-bromoacetamidobenzyl group at the C1-position and (S)-configuration.
http://purl.obolibrary.org/obo/CHEBI_59056	EDTA methidiumpropylamide	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A combined intercalating and chelating reagent. The iron chelate, prepared by adding Fe(NH4)2(SO4)2, effects random oxidative cleavage of DNA in the presence of O2 and a reducing agent. This activity is useful as a footprinting probe.
http://purl.obolibrary.org/obo/CHEBI_59424	bromophenol blue	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 3,5-dibromo-4-hydroxyphenyl groups. It is used as a laboratory indicator, changing from yellow below pH 3 to purple at pH 4.6, and as a size marker for monitoring the progress of agarose gel and polyacrylamide gel electrophoresis. It has also been used as an industrial dye.
http://purl.obolibrary.org/obo/CL_0000000	cell	http://purl.obolibrary.org/obo/UBERON_0000061	anatomical structure		A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane.
http://purl.obolibrary.org/obo/CL_0000001	primary cultured cell	http://purl.obolibrary.org/obo/CL_0000010	cultured cell		A cultured cell that is freshly isolated from a organismal source, or derives in culture from such a cell prior to the culture being passaged.
http://purl.obolibrary.org/obo/CL_0000003	obsolete native cell	http://purl.obolibrary.org/obo/CL_0000000	cell		OBSOLETE. A cell that is found in a natural setting, which includes multicellular organism cells 'in vivo' (i.e. part of an organism), and unicellular organisms 'in environment' (i.e. part of a natural environment).
http://purl.obolibrary.org/obo/CL_0000010	cultured cell	http://purl.obolibrary.org/obo/CL_0000578	experimentally modified cell in vitro		A cell in vitro that is or has been maintained or propagated as part of a cell culture.
http://purl.obolibrary.org/obo/CL_0000019	sperm	http://purl.obolibrary.org/obo/CL_0000000	cell		A mature male germ cell that develops from a spermatid.
http://purl.obolibrary.org/obo/CL_0000057	fibroblast	http://purl.obolibrary.org/obo/CL_0000000	cell		A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped.
http://purl.obolibrary.org/obo/CL_0000066	epithelial cell	http://purl.obolibrary.org/obo/CL_0000000	cell		A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina.
http://purl.obolibrary.org/obo/CL_0000077	mesothelial cell	http://purl.obolibrary.org/obo/CL_0000066	epithelial cell		A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement.
http://purl.obolibrary.org/obo/CL_0000084	T cell	http://purl.obolibrary.org/obo/CL_0000542	lymphocyte		A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
http://purl.obolibrary.org/obo/CL_0000097	mast cell	http://purl.obolibrary.org/obo/CL_0000000	cell		A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development.
http://purl.obolibrary.org/obo/CL_0000101	sensory neuron	http://purl.obolibrary.org/obo/CL_0000540	neuron		Any neuron having a sensory function; an afferent neuron conveying sensory impulses.
http://purl.obolibrary.org/obo/CL_0000182	hepatocyte	http://purl.obolibrary.org/obo/CL_0000066	epithelial cell		The main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules. Majority of cell population of liver, polygonal in shape, arranged in plates or trabeculae between sinusoids; may have single nucleus or binucleated.
http://purl.obolibrary.org/obo/CL_0000232	erythrocyte	http://purl.obolibrary.org/obo/CL_0000000	cell		A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen.
http://purl.obolibrary.org/obo/CL_0000233	platelet	http://purl.obolibrary.org/obo/CL_0000000	cell		A non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
http://purl.obolibrary.org/obo/CL_0000235	macrophage	http://purl.obolibrary.org/obo/CL_0000000	cell		A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells.
http://purl.obolibrary.org/obo/CL_0000236	B cell	http://purl.obolibrary.org/obo/CL_0000542	lymphocyte		A lymphocyte of B lineage that is capable of B cell mediated immunity.
http://purl.obolibrary.org/obo/CL_0000451	dendritic cell	http://purl.obolibrary.org/obo/CL_0000000	cell		A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative).
http://purl.obolibrary.org/obo/CL_0000540	neuron	http://purl.obolibrary.org/obo/CL_0002319	neural cell		The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
http://purl.obolibrary.org/obo/CL_0000542	lymphocyte	http://purl.obolibrary.org/obo/CL_0000842	mononuclear cell		A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
http://purl.obolibrary.org/obo/CL_0000556	megakaryocyte	http://purl.obolibrary.org/obo/CL_0000000	cell		A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release.
http://purl.obolibrary.org/obo/CL_0000558	reticulocyte	http://purl.obolibrary.org/obo/CL_0000000	cell		An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds.
http://purl.obolibrary.org/obo/CL_0000560	band form neutrophil	http://purl.obolibrary.org/obo/CL_0000775	neutrophil		A late neutrophilic metamyelocyte in which the nucleus is indented to more than half the distance to the farthest nuclear margin but in no area being condensed to a single filament. The nucleus is in the form of a curved or coiled band, not having acquired the typical multilobar shape of the mature neutrophil. These cells are fMLP receptor-positive, CD11b-positive, CD35-negative, and CD49d-negative.
http://purl.obolibrary.org/obo/CL_0000562	nucleate erythrocyte	http://purl.obolibrary.org/obo/CL_0000232	erythrocyte		An erythrocyte having a nucleus.
http://purl.obolibrary.org/obo/CL_0000576	monocyte	http://purl.obolibrary.org/obo/CL_0000842	mononuclear cell		Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.
http://purl.obolibrary.org/obo/CL_0000578	experimentally modified cell in vitro	http://purl.obolibrary.org/obo/CL_0000000	cell		A cell in vitro that has undergone physical changes as a consequence of a deliberate and specific experimental procedure.
http://purl.obolibrary.org/obo/CL_0000623	natural killer cell	http://purl.obolibrary.org/obo/CL_0000542	lymphocyte		A lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation via germline encoded activation receptors and also regulate immune responses via cytokine release and direct contact with other cells.
http://purl.obolibrary.org/obo/CL_0000624	CD4-positive, alpha-beta T cell	http://purl.obolibrary.org/obo/CL_0000789	alpha-beta T cell		A mature alpha-beta T cell that expresses an alpha-beta T cell receptor and the CD4 coreceptor.
http://purl.obolibrary.org/obo/CL_0000625	CD8-positive, alpha-beta T cell	http://purl.obolibrary.org/obo/CL_0000789	alpha-beta T cell		A T cell expressing an alpha-beta T cell receptor and the CD8 coreceptor.
http://purl.obolibrary.org/obo/CL_0000738	leukocyte	http://purl.obolibrary.org/obo/CL_0000000	cell		An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
http://purl.obolibrary.org/obo/CL_0000767	basophil	http://purl.obolibrary.org/obo/CL_0000000	cell		Any of the immature or mature forms of a granular leukocyte that in its mature form has an irregularly shaped, pale-staining nucleus that is partially constricted into two lobes, and with cytoplasm that contains coarse, bluish-black granules of variable size. Basophils contain vasoactive amines such as histamine and serotonin, which are released on appropriate stimulation. A basophil is CD123-positive, CD193-positive, CD203c-positive, and FceRIa-positive.
http://purl.obolibrary.org/obo/CL_0000771	eosinophil	http://purl.obolibrary.org/obo/CL_0000738	leukocyte		Any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin. Eosinophils are CD9-positive, CD191-positive, and CD193-positive.
http://purl.obolibrary.org/obo/CL_0000775	neutrophil	http://purl.obolibrary.org/obo/CL_0000738	leukocyte		Any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
http://purl.obolibrary.org/obo/CL_0000776	immature neutrophil	http://purl.obolibrary.org/obo/CL_0000775	neutrophil		Any of the immature forms of a neutrophil in which neutrophilic specific granules are present but other phenotypic features of the mature form may be lacking.
http://purl.obolibrary.org/obo/CL_0000786	plasma cell	http://purl.obolibrary.org/obo/CL_0000236	B cell		A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.
http://purl.obolibrary.org/obo/CL_0000789	alpha-beta T cell	http://purl.obolibrary.org/obo/CL_0000084	T cell		A T cell that expresses an alpha-beta T cell receptor complex.
http://purl.obolibrary.org/obo/CL_0000794	CD8-positive, alpha-beta cytotoxic T cell	http://purl.obolibrary.org/obo/CL_0000625	CD8-positive, alpha-beta T cell		A CD8-positive, alpha-beta T cell that is capable of killing target cells in an antigen specific manner with the phenotype perforin-positive and granzyme B-positive.
http://purl.obolibrary.org/obo/CL_0000814	mature NK T cell	http://purl.obolibrary.org/obo/CL_0000789	alpha-beta T cell		A mature alpha-beta T cell of a distinct lineage that bears natural killer markers and a T cell receptor specific for a limited set of ligands. NK T cells have activation and regulatory roles particularly early in an immune response.
http://purl.obolibrary.org/obo/CL_0000836	promyelocyte	http://purl.obolibrary.org/obo/CL_0000000	cell		A precursor in the granulocytic series, being a cell intermediate in development between a myeloblast and myelocyte, that has distinct nucleoli, a nuclear-to-cytoplasmic ratio of 5:1 to 3:1, and containing a few primary cytoplasmic granules. Markers for this cell are fucosyltransferase FUT4-positive, CD33-positive, integrin alpha-M-negative, low affinity immunoglobulin gamma Fc region receptor III-negative, and CD24-negative.
http://purl.obolibrary.org/obo/CL_0000842	mononuclear cell	http://purl.obolibrary.org/obo/CL_0000000	cell		A leukocyte with a single non-segmented nucleus in the mature form.
http://purl.obolibrary.org/obo/CL_0002192	metamyelocyte	http://purl.obolibrary.org/obo/CL_0000000	cell		A eosinophil precursor in the granulocytic series, being a cell intermediate in development between a myelocyte and a band form cell. The nucleus becomes indented where the indentation is smaller than half the distance to the farthest nuclear margin; chromatin becomes coarse and clumped; specific granules predominate while primary granules are rare.
http://purl.obolibrary.org/obo/CL_0002193	myelocyte	http://purl.obolibrary.org/obo/CL_0000000	cell		A cell type that is the first of the maturation stages of the granulocytic leukocytes normally found in the bone marrow. Granules are seen in the cytoplasm. The nuclear material of the myelocyte is denser than that of the myeloblast but lacks a definable membrane. The cell is flat and contains increasing numbers of granules as maturation progresses.
http://purl.obolibrary.org/obo/CL_0002319	neural cell	http://purl.obolibrary.org/obo/CL_0000000	cell		A cell that is part of the nervous system.
http://purl.obolibrary.org/obo/CL_2000001	peripheral blood mononuclear cell	http://purl.obolibrary.org/obo/CL_0000842	mononuclear cell		A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood.
http://purl.obolibrary.org/obo/UBERON_0000007	pituitary gland	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN].
http://purl.obolibrary.org/obo/UBERON_0000010	peripheral nervous system	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
http://purl.obolibrary.org/obo/UBERON_0000029	lymph node	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Any of the rounded masses of lymphoid tissue that are surrounded by a capsule of connective tissue, are distributed along the lymphatic vessels, and contain numerous lymphocytes which filter the flow of lymph.
http://purl.obolibrary.org/obo/UBERON_0000165	mouth	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks).
http://purl.obolibrary.org/obo/UBERON_0000178	blood	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		A fluid that is composed of blood plasma and erythrocytes.
http://purl.obolibrary.org/obo/UBERON_0000945	stomach	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		An expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. A stomach is lined, in whole or in part by a glandular epithelium.
http://purl.obolibrary.org/obo/UBERON_0000948	heart	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.
http://purl.obolibrary.org/obo/UBERON_0000955	brain	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP].
http://purl.obolibrary.org/obo/UBERON_0000970	eye	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		An organ that detects light.
http://purl.obolibrary.org/obo/UBERON_0000992	ovary	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The gonad of a female organism which contains germ cells.
http://purl.obolibrary.org/obo/UBERON_0000995	uterus	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The female muscular organ of gestation in which the developing embryo or fetus is nourished until birth.
http://purl.obolibrary.org/obo/UBERON_0000996	vagina	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A fibromuscular tubular tract leading from the uterus to the exterior of the body in female placental mammals and marsupials, or to the cloaca in female birds, monotremes, and some reptiles[WP].
http://purl.obolibrary.org/obo/UBERON_0001004	respiratory system	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Functional system which consists of structures involved in respiration.
http://purl.obolibrary.org/obo/UBERON_0001052	rectum	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The terminal portion of the intestinal tube, terminating with the anus.
http://purl.obolibrary.org/obo/UBERON_0001103	diaphragm	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control.
http://purl.obolibrary.org/obo/UBERON_0001134	skeletal muscle tissue	http://purl.obolibrary.org/obo/UBERON_0000479	tissue		Muscle tissue that consists primarily of skeletal muscle fibers.
http://purl.obolibrary.org/obo/UBERON_0001155	colon	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A portion of the large intestine before it becomes the rectum. In mammals, the colon is the most part of the large intestine, excluding the vermiform appendix, the rectum and the anal canal.
http://purl.obolibrary.org/obo/UBERON_0001159	sigmoid colon	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The part of the large intestine that is closest to the rectum and anus. It forms a loop that averages about 40 cm. in length, and normally lies within the pelvis, but on account of its freedom of movement it is liable to be displaced into the abdominal cavity.
http://purl.obolibrary.org/obo/UBERON_0001255	urinary bladder	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Distensible musculomembranous organ situated in the anterior part of the pelvic cavity in which urine collects before excretion[MP].
http://purl.obolibrary.org/obo/UBERON_0001323	tibial nerve	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The tibial nerve is a branch of the sciatic nerve. The tibial nerve passes through the popliteal fossa to pass below the arch of soleus. In the popliteal fossa the nerve gives off branches to gastrocnemius, popliteus, soleus and plantaris muscles, an articular branch to the knee joint, and a cutaneous branch that will become the sural nerve. The sural nerve is joined by fibres from the common peroneal nerve and runs down the calf to supply the lateral side of the foot. Below the soleus muscle the nerve lies close to the tibia and supplies the tibialis posterior, the flexor digitorum longus and the flexor hallucis longus. The nerve passes into the foot running posterior to the medial malleolus. Here it is bound down by the flexor retinaculum in company with the posterior tibial artery. [WP,unvetted].
http://purl.obolibrary.org/obo/UBERON_0001558	lower respiratory tract	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified].
http://purl.obolibrary.org/obo/UBERON_0001637	artery	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition].
http://purl.obolibrary.org/obo/UBERON_0001723	tongue	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A muscular organ in the floor of the mouth.
http://purl.obolibrary.org/obo/UBERON_0001811	conjunctiva	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The mucous membrane that lines the inner surface of the eyelids and the front of the eyeball.
http://purl.obolibrary.org/obo/UBERON_0001982	capillary	http://purl.obolibrary.org/obo/UBERON_0001981	blood vessel		Any of the smallest blood vessels connecting arterioles with venules.
http://purl.obolibrary.org/obo/UBERON_0002046	thyroid gland	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A two-lobed endocrine gland found in all vertebrates, located in front of and on either side of the trachea in humans, and producing various hormones, such as triiodothyronine and calcitonin[BTO].
http://purl.obolibrary.org/obo/UBERON_0002048	lung	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Respiration organ that develops as an outpocketing of the esophagus.
http://purl.obolibrary.org/obo/UBERON_0002106	spleen	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The organ that functions to filter blood and to store red corpuscles and platelets.
http://purl.obolibrary.org/obo/UBERON_0002107	liver	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		An exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes[GO].
http://purl.obolibrary.org/obo/UBERON_0002116	ileum	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The portion of the small intestine that extends from the jejunum to the colon.
http://purl.obolibrary.org/obo/UBERON_0002358	peritoneum	http://purl.obolibrary.org/obo/UBERON_0000481	multi-tissue structure		A serous membrane that lines the peritoneal cavity[VHOG,modified].
http://purl.obolibrary.org/obo/UBERON_0002367	prostate gland	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
http://purl.obolibrary.org/obo/UBERON_0002389	manual digit	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A digit that is part of a manus (hand).
http://purl.obolibrary.org/obo/UBERON_0002391	lymph	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		Lymph is the fluid that is formed when interstitial fluid enters the conduits of the lymphatic system through lymph capillaries[WP].
http://purl.obolibrary.org/obo/UBERON_0003126	trachea	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph].
http://purl.obolibrary.org/obo/OBI_0002460	defined population inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that is based on fitting within the defined characteristics of a population based study design.
http://purl.obolibrary.org/obo/OBI_0002573	polyA depleted RNA extract	http://purl.obolibrary.org/obo/OBI_0000880	RNA extract		A RNA extract that is the output of an extraction process in which RNA molecules lacking poly A tails at thier 3' ends are purified.
http://purl.obolibrary.org/obo/OBI_0002574	RNA extraction with polyA depletion	http://purl.obolibrary.org/obo/OBI_0666666	RNA extraction		A RNA extraction process in which only RNAs lacking a polyA tail are retained
http://purl.obolibrary.org/obo/OBI_0003289	mosquito membrane feeding device	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that contains blood in a membrane penetrable to mosquitoes, designed to feed mosquitoes without the need for an animal host.
http://purl.obolibrary.org/obo/OBI_0003113	proximity extension assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay		An analyte assay that uses quantitative polymerase chain reaction (qPCR) technology to determine the concentration/presence of an analyte or analyte complex.
http://purl.obolibrary.org/obo/OBI_0003315	assay measuring epitope specific amphiregulin production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects amphiregulin production by T cells.
http://purl.obolibrary.org/obo/GO_0140779	XCL1 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of XCL1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/OBI_0003387	Illumina NextSeq 550	http://purl.obolibrary.org/obo/OBI_0003684	Illumina NextSeq series instrument		A DNA sequencer manufactured by the Illumina corporation, which provides the increased flexibility of microarray scanning in addition to sequencing.
http://purl.obolibrary.org/obo/OBI_0003388	Agilent-026655 Whole Mouse Genome Microarray 4x44K v2	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray manufactured with Agilent 60-mer SurePrint Technology .The SurePrint G3 Mouse Gene Expression 4x44K v2 Microarray provide full coverage of the mouse transcriptome using the latest annotation databases, including long non-coding RNA(lncRNA). Each glass slide is formatted with four high-definition 44K arrays.
http://purl.obolibrary.org/obo/OBI_0003389	Agilent-030493 SurePrint G3 Mouse Exon 4x180K Microarray	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray manufactured with Agilent 60-mer SurePrint Technology for studying exon-level gene expression changes. The SurePrint G3 Mouse Exon 4x180K Microarray include probes targeting individual exons. Each glass slide formatted with four 180K arrays.
http://purl.obolibrary.org/obo/OBI_0003390	Agilent-074809 SurePrint G3 Mouse GE v2 8x60K Microarray	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray manufactured with Agilent 60-mer SurePrint technology which provides comprehensive coverage of genes and transcripts using the latest annotation databases. The SurePrint G3 Mouse Gene Expression 8x60K v2 Microarray features complete coverage of established RefSeq coding transcripts (NM) from the latest build and updated long non-coding RNA (lncRNA) content to ensure relevant research.Each glass slide formatted with eight high-definition 60K arrays.
http://purl.obolibrary.org/obo/OBI_0003399	Affymetrix Clariom S Assay, Human	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray manufactured by Affymetrix, to obtain a gene-level view of the human transcriptome. The assay design covers >20,000 well-annotated genes, providing researchers with the ability to perform gene-level expression profiling studies, to identify expression biomarkers , and to quickly assess changes in key genes and pathways.
http://purl.obolibrary.org/obo/OBI_0003400	Affymetrix Clariom S Assay, Mouse	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray manufactured by Affymetrix, to obtain a gene-level view of the mouse transcriptome. The assay design covers >20,000 well-annotated genes, providing researchers with the ability to perform gene-level expression profiling studies, to identify expression biomarkers, and to quickly assess changes in key genes and pathways.
http://purl.obolibrary.org/obo/OBI_0003401	Illumina HumanHT-12 V4.0 expression beadchip	http://purl.obolibrary.org/obo/OBI_0001869	Illumina BeadChip		An Illumina BeadChip which employs direct-hybridization assay, for whole-genome expression profiling and expression-based quantitative trait loci (eQTL) studies. This BeadChip contains 12 arrays, each featuring more than 48,000 probes, targeting more than 31,000 annotated genes, providing genome-wide coverage of well-characterized genes, gene candidates, and splice variants.
http://purl.obolibrary.org/obo/OBI_0003402	Illumina MouseRef-8 v2.0 beadchip	http://purl.obolibrary.org/obo/OBI_0001869	Illumina BeadChip		An Illumina BeadChip which employs direct-hybridization assay, for whole-genome expression profiling in the mouse.This Beadchip contains 8 microarrays, featuring more than 25,000 probes per array, derived from the NCBI RefSeq database and supplemented with MEEBO and RIKEN FANTOM2 content.
http://purl.obolibrary.org/obo/OBI_0003403	Affymetrix Mouse Exon Junction Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray manufactured by Affymetrix, used to identify exon-exon junctions associated with alternate splice variants in the mouse transcriptome.
http://purl.obolibrary.org/obo/OBI_0003404	Affymetrix Human Exon Junction Array	http://purl.obolibrary.org/obo/OBI_0400148	DNA microarray		A DNA microarray manufactured by Affymetrix, used to identify exon-exon junctions associated with alternate splice variants in the human transcriptome.
http://purl.obolibrary.org/obo/OBI_0003413	administering substance in vivo to cause disease	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of substance in vivo with the intention to induce disease in the organism.
http://purl.obolibrary.org/obo/OBI_0003417	antigen specific antibodies assay datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of an antigen specific antibodies assay.
http://purl.obolibrary.org/obo/OBI_0003418	antigen specific antibodies in blood assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An antigen specific antibodies assay that has a blood specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003419	antigen specific antibodies in milk assay	http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay		An antigen specific antibodies assay that has a milk specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003420	antigen specific antibodies in blood assay datum	http://purl.obolibrary.org/obo/OBI_0003417	antigen specific antibodies assay datum		An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in blood assay.
http://purl.obolibrary.org/obo/OBI_0003421	antigen specific antibodies in milk assay datum	http://purl.obolibrary.org/obo/OBI_0003417	antigen specific antibodies assay datum		An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in milk assay.
http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay in which the level of catalytic activity of an enzyme is determined.
http://purl.obolibrary.org/obo/OBI_0003423	5'-nucleotidase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of 5'-nucleotidase in a sample.
http://purl.obolibrary.org/obo/OBI_0003424	alanine aminotransferase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of alanine aminotransferase in a sample.
http://purl.obolibrary.org/obo/OBI_0003425	alkaline phosphatase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of alkaline phosphatase in a sample.
http://purl.obolibrary.org/obo/OBI_0003426	amylase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of amylase in a sample.
http://purl.obolibrary.org/obo/OBI_0003427	aspartate aminotransferase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of aspartate aminotransferase in a sample.
http://purl.obolibrary.org/obo/OBI_0003428	cholinesterase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of cholinesterase in a sample.
http://purl.obolibrary.org/obo/OBI_0003429	creatine kinase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of creatine kinase in a sample.
http://purl.obolibrary.org/obo/OBI_0003430	gamma-glutamyltransferase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of gamma-glutamyltransferase in a sample.
http://purl.obolibrary.org/obo/OBI_0003431	glutamate dehydrogenase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of glutamate dehydrogenase in a sample.
http://purl.obolibrary.org/obo/OBI_0003432	isocitrate dehydrogenase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of isocitrate dehydrogenase in a sample.
http://purl.obolibrary.org/obo/OBI_0003433	lactate dehydrogenase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of lactate dehydrogenase in a sample.
http://purl.obolibrary.org/obo/OBI_0003434	sorbitol dehydrogenase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of sorbitol dehydrogenase in a sample.
http://purl.obolibrary.org/obo/OBI_0003435	acyl-CoA oxidase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of Acyl-CoA oxidase in a sample.
http://purl.obolibrary.org/obo/OBI_0003436	N-acetyl-beta-glucosaminidase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of N-acetyl-beta-glucosaminidase in a sample.
http://purl.obolibrary.org/obo/OBI_0003437	ribonuclease activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of ribonuclease in a sample.
http://purl.obolibrary.org/obo/OBI_0003438	galactosidase activity level assay	http://purl.obolibrary.org/obo/OBI_0003422	enzymatic activity level assay		An enzymatic activity level assay that measures the activity of galactosidase in a sample.
http://purl.obolibrary.org/obo/OBI_0003454	Mosquito Magnet Liberty Plus trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that is designed to emit a combination of carbon dioxide, heat, water, and oct-1-en-3-ol attractants while simultaneously using suction to trap arthropods. This trap has the same design as the Mosquito Magnet Pro trap but is smaller, is more lightweight, and uses a main line electricity supply instead of propane to power itself. Both use propane to produce the arthropod attractor.
http://purl.obolibrary.org/obo/OBI_0003455	tumor challenge	http://purl.obolibrary.org/obo/OBI_0003456	in vivo challenge		The administration of a malignant cell to a host.
http://purl.obolibrary.org/obo/OBI_0003456	in vivo challenge	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		The administration of a challenge to a live host.
http://purl.obolibrary.org/obo/OBI_0003460	in vivo assay measuring T cell epitope specific protection from pathogen challenge	http://purl.obolibrary.org/obo/OBI_0002073	in vivo assay measuring T cell epitope specific protection from challenge		An in vivo assay measuring T cell epitope specific protection from pathogen challenge.
http://purl.obolibrary.org/obo/OBI_0003461	in vivo assay measuring T cell epitope specific protection from tumor challenge	http://purl.obolibrary.org/obo/OBI_0002073	in vivo assay measuring T cell epitope specific protection from challenge		An in vivo assay measuring T cell epitope specific protection from tumor challenge.
http://purl.obolibrary.org/obo/OBI_0003462	in vivo assay measuring T cell epitope specific protection from other challenge	http://purl.obolibrary.org/obo/OBI_0002073	in vivo assay measuring T cell epitope specific protection from challenge		An in vivo assay measuring T cell epitope specific protection from a challenge other than pathogen, infection, or tumor.
http://purl.obolibrary.org/obo/OBI_0003463	in vivo assay measuring T cell epitope specific survival after tumor challenge	http://purl.obolibrary.org/obo/OBI_0003461	in vivo assay measuring T cell epitope specific protection from tumor challenge		An in vivo assay measuring T cell epitope specific protection from tumor challenge using survival.
http://purl.obolibrary.org/obo/OBI_0003464	in vivo assay measuring T cell epitope specific survival after pathogen challenge	http://purl.obolibrary.org/obo/OBI_0003460	in vivo assay measuring T cell epitope specific protection from pathogen challenge		An in vivo assay measuring T cell epitope specific protection from pathogen challenge using survival.
http://purl.obolibrary.org/obo/OBI_0003465	in vivo assay measuring B cell epitope specific protection from pathogen challenge	http://purl.obolibrary.org/obo/OBI_0001710	in vivo assay measuring B cell epitope specific protection from challenge		An in vivo assay measuring B cell epitope specific protection from pathogen challenge.
http://purl.obolibrary.org/obo/OBI_0003466	in vivo assay measuring B cell epitope specific protection from tumor challenge	http://purl.obolibrary.org/obo/OBI_0001710	in vivo assay measuring B cell epitope specific protection from challenge		An in vivo assay measuring B cell epitope specific protection from tumor challenge.
http://purl.obolibrary.org/obo/OBI_0003468	in vivo assay measuring B cell epitope specific survival after pathogen challenge	http://purl.obolibrary.org/obo/OBI_0003465	in vivo assay measuring B cell epitope specific protection from pathogen challenge		An in vivo assay measuring B cell epitope specific protection from pathogen challenge using survival.
http://purl.obolibrary.org/obo/OBI_0003469	in vivo assay measuring B cell epitope specific survival after tumor challenge	http://purl.obolibrary.org/obo/OBI_0003466	in vivo assay measuring B cell epitope specific protection from tumor challenge		An in vivo assay measuring B cell epitope specific protection from tumor challenge using survival.
http://purl.obolibrary.org/obo/OBI_0003470	in vivo assay measuring T cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002637	in vivo assay measuring T cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring a T cell epitope specific protection from a pathogen challenge after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0003471	in vivo assay measuring T cell epitope specific pathogen protection from challenge resulting from the adoptive transfer of epitope specific T cells based on survival	http://purl.obolibrary.org/obo/OBI_0003470	in vivo assay measuring T cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring T cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific T cells using survival.
http://purl.obolibrary.org/obo/OBI_0003472	in vivo assay measuring T cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002637	in vivo assay measuring T cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring a T cell epitope specific protection from a tumor challenge after adoptive transfer of epitope specific T cells.
http://purl.obolibrary.org/obo/OBI_0003473	in vivo assay measuring T cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific T cells based on survival	http://purl.obolibrary.org/obo/OBI_0003472	in vivo assay measuring T cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring T cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific T cells using survival.
http://purl.obolibrary.org/obo/OBI_0003474	in vivo assay measuring T cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002637	in vivo assay measuring T cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring a T cell epitope specific protection from other challenge after adoptive transfer of epitope specific T cells.
http://purl.obolibrary.org/obo/OBI_0003475	in vivo assay measuring B cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002638	in vivo assay measuring B cell epitope specific protection from challenge resulting from adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring a B cell epitope specific protection from a pathogen challenge after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0003476	in vivo assay measuring B cell epitope specific pathogen protection from challenge resulting from the adoptive transfer of epitope specific antibodies or B cells based on survival	http://purl.obolibrary.org/obo/OBI_0003475	in vivo assay measuring B cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring B cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific antibodies or B cells using survival.
http://purl.obolibrary.org/obo/OBI_0003477	in vivo assay measuring B cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002638	in vivo assay measuring B cell epitope specific protection from challenge resulting from adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring a B cell epitope specific protection from a tumor challenge after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0003478	in vivo assay measuring B cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific antibodies or B cells based on survival	http://purl.obolibrary.org/obo/OBI_0003477	in vivo assay measuring B cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring B cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific antibodies or B cells using survival.
http://purl.obolibrary.org/obo/OBI_0003479	in vivo assay measuring B cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002638	in vivo assay measuring B cell epitope specific protection from challenge resulting from adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring a B cell epitope specific protection from other challenge after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0003480	Gram stain assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that identifies bacteria based on the differential retention of a crystal violet-iodine complex within the cell wall.
http://purl.obolibrary.org/obo/OBI_0003481	cow-baited arthropod trap	http://purl.obolibrary.org/obo/OBI_0000968	device		A resting arthropod trap that consists of a tent inside which an adult cow is tethered to the ground, in order to attract arthropods and collect those that rest on the interior walls of the tent.
http://purl.obolibrary.org/obo/OBI_0003482	lymph specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from a portion of lymph collected from an organism.
http://purl.obolibrary.org/obo/OBI_0003483	digestive tract specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from part of a digestive tract.
http://purl.obolibrary.org/obo/OBI_0003484	assay measuring epitope specific interleukin-25 production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interleukin-25 production by T cells.
http://purl.obolibrary.org/obo/OBI_0003485	detection of specific nucleic acids with complementary probes assay measuring epitope specific interleukin-25 production by T cells	http://purl.obolibrary.org/obo/OBI_0003484	assay measuring epitope specific interleukin-25 production by T cells		A detection of specific nucleic acid polymers with complementary probes that detects interleukin-25 production by T cells.
http://purl.obolibrary.org/obo/OBI_0003486	intracellular cytokine staining assay measuring epitope specific interleukin-25 production by T cells	http://purl.obolibrary.org/obo/OBI_0003484	assay measuring epitope specific interleukin-25 production by T cells		A flow cytometry assay that detects interleukin-25 production by T cells.
http://purl.obolibrary.org/obo/OBI_0003487	ELISA measuring epitope specific interleukin-25 production by T cells	http://purl.obolibrary.org/obo/OBI_0003484	assay measuring epitope specific interleukin-25 production by T cells		An enzyme-linked immunosorbent assay that detects interleukin-25 production by T cells.
http://purl.obolibrary.org/obo/OBI_0003711	grip strength assay	http://purl.obolibrary.org/obo/OBI_0003533	nervous system functionality assessment		A nervous system functionality assessment that uses the grip strength of a lab animal to measure neuromuscular function.
http://purl.obolibrary.org/obo/CHEBI_16670	peptide	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc.
http://purl.obolibrary.org/obo/CHEBI_35366	fatty acid	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids.
http://purl.obolibrary.org/obo/CHEBI_168396	mycophenolic acid	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases.
http://purl.obolibrary.org/obo/CHEBI_20067	3-hydroxybutyric acid	http://purl.obolibrary.org/obo/CHEBI_35366	fatty acid		A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
http://purl.obolibrary.org/obo/CHEBI_23965	estradiol	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A 3-hydroxy steroid that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17.
http://purl.obolibrary.org/obo/CHEBI_25078	luciferin	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A low-molecular-mass compound present in bioluminescent organisms that emits light when oxidized in presence of enzyme luciferase.
http://purl.obolibrary.org/obo/CHEBI_27226	uric acid	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An oxopurine that is the final oxidation product of purine metabolism.
http://purl.obolibrary.org/obo/CHEBI_30660	thyroxine	http://purl.obolibrary.org/obo/CHEBI_33709	amino acid		An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
http://purl.obolibrary.org/obo/CHEBI_33697	ribonucleic acid	http://purl.obolibrary.org/obo/CHEBI_33696	nucleic acid		High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins.
http://purl.obolibrary.org/obo/CHEBI_35780	phosphate ion	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A phosphorus oxoanion that is the conjugate base of phosphoric acid.
http://purl.obolibrary.org/obo/CHEBI_39127	magnesium cation	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Any magnesium ion that is positively charged.
http://purl.obolibrary.org/obo/CHEBI_4431	deoxyribonucleotide	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A nucleotide in which the ribose moiety has one or more of its hydroxy groups substituted by hydrogen.
http://purl.obolibrary.org/obo/CHEBI_61073	oxygen radical	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An inorganic radical in which a free electron resides on one or more oxygen atoms of an oxygen species.
http://purl.obolibrary.org/obo/CHEBI_31642	gadodiamide hydrate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		The hydrate of gadodiamide.
http://purl.obolibrary.org/obo/CHEBI_31643	gadoteridol	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A non-ionic gadolinium chelate having a macrocyclic tetraamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).
http://purl.obolibrary.org/obo/CHEBI_31991	phenol red	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		3H-2,1-Benzoxathiole 1,1-dioxide in which both of the hydrogens at position 3 have been substituted by 4-hydroxyphenyl groups. A pH indicator changing colour from yellow below pH 6.8 to bright pink above pH 8.2, it is commonly used as an indicator in cell cultures and in home swimming pool test kits. It is also used in the (now infrequently performed) phenolsulfonphthalein (PSP) test for estimation of overall blood flow through the kidney.
http://purl.obolibrary.org/obo/CHEBI_32142	sodium citrate dihydrate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		The dihydrate of trisodium citrate.
http://purl.obolibrary.org/obo/CHEBI_37333	gadodiamide	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A non-ionic gadolinium chelate having a macrocyclic triamine framework. It is used as a paramagnetic contrast agent in magnetic resonance imaging (MRI).
http://purl.obolibrary.org/obo/CHEBI_33359	rhodium atom	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A cobalt group element atom of atomic number 45.
http://purl.obolibrary.org/obo/CHEBI_472552	5-bromo-2'-deoxyuridine	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A pyrimidine 2'-deoxyribonucleoside compound having 5-bromouracil as the nucleobase.
http://purl.obolibrary.org/obo/CHEBI_59051	diethyl pyrocarbonate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		The diethyl ester of dicarbonic acid.
http://purl.obolibrary.org/obo/CHEBI_52673	Alexa Fluor 555	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		A fluorescent dye of absorption wavelength 555 nm and emission wavelength 565 nm, derived from a 3,6-diaminoxanthene-4,5-disulfate.
http://purl.obolibrary.org/obo/CHEBI_86319	25-hydroxyvitamin D2	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A hydroxycalciol that is vitamin D2 in which the hydrogen at position 25 has been replaced by a hydroxy group.
http://purl.obolibrary.org/obo/GO_0004842	ubiquitin-protein transferase activity	http://purl.obolibrary.org/obo/GO_0003674	gene product or complex activity		Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y = Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
http://purl.obolibrary.org/obo/GO_0005216	monoatomic ion channel activity	http://purl.obolibrary.org/obo/GO_0009987	cellular process		Enables the facilitated diffusion of a monoatomic ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
http://purl.obolibrary.org/obo/GO_0005575	cellular_component	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex).
http://purl.obolibrary.org/obo/GO_0005577	fibrinogen complex	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
http://purl.obolibrary.org/obo/GO_0006006	glucose metabolic process	http://purl.obolibrary.org/obo/GO_0008150	biological process		The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
http://purl.obolibrary.org/obo/GO_0006338	chromatin remodeling	http://purl.obolibrary.org/obo/GO_0009987	cellular process		A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
http://purl.obolibrary.org/obo/GO_0007283	spermatogenesis	http://purl.obolibrary.org/obo/GO_0022414	reproductive process		The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa.
http://purl.obolibrary.org/obo/GO_0007588	excretion	http://purl.obolibrary.org/obo/GO_0008150	biological process		A process which includes removal of a compound from the body through various routes such as urine, feces and exhalation.
http://purl.obolibrary.org/obo/GO_0007596	blood coagulation	http://purl.obolibrary.org/obo/GO_0008150	biological process		The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
http://purl.obolibrary.org/obo/GO_0007611	learning or memory	http://purl.obolibrary.org/obo/GO_0008150	biological process		The acquisition and processing of information and/or the storage and retrieval of this information over time.
http://purl.obolibrary.org/obo/GO_0008152	metabolic process	http://purl.obolibrary.org/obo/GO_0009987	cellular process		A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well  macromolecular processes such as DNA repair and replication, protein synthesis and degradation.
http://purl.obolibrary.org/obo/GO_0009566	fertilization	http://purl.obolibrary.org/obo/GO_0008150	biological process		The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
http://purl.obolibrary.org/obo/GO_0015925	galactosidase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.
http://purl.obolibrary.org/obo/GO_0016160	amylase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the hydrolysis of amylose or an amylose derivative.
http://purl.obolibrary.org/obo/GO_0016788	hydrolase activity, acting on ester bonds	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the hydrolysis of any ester bond.
http://purl.obolibrary.org/obo/GO_0021700	developmental maturation	http://purl.obolibrary.org/obo/GO_0008150	biological process		A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
http://purl.obolibrary.org/obo/GO_0033036	macromolecule localization	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process in which a macromolecule is transported to, or maintained in, a specific location.
http://purl.obolibrary.org/obo/GO_0050896	response to stimulus	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
http://purl.obolibrary.org/obo/GO_0070288	ferritin complex	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A protein complex that binds iron and acts as a major iron storage system. There are three major subclasses of ferritins: the classical ferritins (Ftn), the heme-containing bacterioferritins (Bfr) and the DNA-binding proteins from starved cells (Dps). Ftn and Bfr are made of 24 subunits, whereas Dps are smaller with 12 subunits. Ftn is found in most kindoms, while Bfr and Dps are restricted to prokaryotes.
http://purl.obolibrary.org/obo/GO_0047823	D-glutamyltransferase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: D-glutamate + D-glutamine = gamma-D-glutamyl-D-glutamate + NH4+. Can also transfer additional glutamyl residues to a peptide, extending the polypeptide chain.
http://purl.obolibrary.org/obo/UBERON_0000061	anatomical structure	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome.
http://purl.obolibrary.org/obo/UBERON_0000105	life cycle stage	http://purl.obolibrary.org/obo/GO_0008150	biological process		A spatiotemporal region encompassing some part of the life cycle of an organism.
http://purl.obolibrary.org/obo/UBERON_0000122	neuron projection bundle	http://purl.obolibrary.org/obo/UBERON_0000061	anatomical structure		A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses.
http://purl.obolibrary.org/obo/UBERON_0000162	cloaca	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures.
http://purl.obolibrary.org/obo/UBERON_0000173	amniotic fluid	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		Amniotic fluid is a bodily fluid consisting of watery liquid surrounding and cushioning a growing fetus within the amnion. It allows the fetus to move freely without the walls of the uterus being too tight against its body. Buoyancy is also provided. The composition of the fluid changes over the course of gestation. Initially, amniotic fluid is similar to maternal plasma, mainly water with electrolytes. As the fetus develops, proteins, carbohydrates, lipids, phospholipids originating from the lungs, fetal cells, and urea are deposited in the fluid.
http://purl.obolibrary.org/obo/UBERON_0000305	amnion	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The thin innermost layer of the extraembryonic membranes that contains the amniotic fluid; the membrane forms a closed sac in which the embryo and later, the fetus, is suspended and protected.
http://purl.obolibrary.org/obo/UBERON_0000316	cervical mucus	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		A substance produced by the cervix and endocervical glands[BTO]. Thick acidic mucus that blocks the cervical os after mestruation[WP]. This 'infertile' mucus blocks spermatozoa from entering the uterus.
http://purl.obolibrary.org/obo/UBERON_0000341	throat	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		In anatomy, the throat is the anterior part of the neck, in front of the vertebral column. It consists of the pharynx and larynx. An important feature of the throat is the epiglottis, a flap which separates the esophagus from the trachea and prevents inhalation of food or drink. The throat contains various blood vessels, various pharyngeal muscles, the trachea (windpipe) and the esophagus. The hyoid bone and the clavicle are the only bones located in the throat of mammals. It is sometimes considered a synonym for fauces. [WP,unvetted].
http://purl.obolibrary.org/obo/UBERON_0000362	renal medulla	http://purl.obolibrary.org/obo/UBERON_0000481	multi-tissue structure		The inner portion of the kidney consisting of the renal pyramids.
http://purl.obolibrary.org/obo/UBERON_0000463	organism substance	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body.
http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity	http://purl.obolibrary.org/obo/UBERON_0001062	anatomical entity		Anatomical entity that has mass.
http://purl.obolibrary.org/obo/UBERON_0000466	immaterial anatomical entity	http://purl.obolibrary.org/obo/UBERON_0001062	anatomical entity		Anatomical entity that has no mass.
http://purl.obolibrary.org/obo/UBERON_0000477	anatomical cluster	http://purl.obolibrary.org/obo/BFO_0000040	material entity		Anatomical group whose component anatomical structures lie in close proximity to each other.
http://purl.obolibrary.org/obo/UBERON_0000479	tissue	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation.
http://purl.obolibrary.org/obo/UBERON_0000481	multi-tissue structure	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types.
http://purl.obolibrary.org/obo/UBERON_0000483	epithelium	http://purl.obolibrary.org/obo/UBERON_0000479	tissue		Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO].
http://purl.obolibrary.org/obo/UBERON_0000956	cerebral cortex	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex.
http://purl.obolibrary.org/obo/UBERON_0000978	leg	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The portion of the hindlimb that contains both the stylopod and zeugopod.
http://purl.obolibrary.org/obo/UBERON_0001013	adipose tissue	http://purl.obolibrary.org/obo/UBERON_0000479	tissue		Portion of connective tissue composed of adipocytes enmeshed in areolar tissue.
http://purl.obolibrary.org/obo/UBERON_0001062	anatomical entity	http://purl.obolibrary.org/obo/BFO_0000004	independent continuant		Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species.
http://purl.obolibrary.org/obo/UBERON_0001087	pleural fluid	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		Transudate contained in the pleural cavity.
http://purl.obolibrary.org/obo/UBERON_0001088	urine	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		Excretion that is the output of a kidney.
http://purl.obolibrary.org/obo/UBERON_0001089	sweat	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		Secretion produced by a sweat gland.
http://purl.obolibrary.org/obo/UBERON_0001090	synovial fluid	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		Joint fluid is a transudate of plasma that is actively secreted by synovial cells.
http://purl.obolibrary.org/obo/UBERON_0001225	cortex of kidney	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Outer cortical portion of the kidney, between the renal capsule and the renal medulla.
http://purl.obolibrary.org/obo/UBERON_0001268	peritoneal fluid	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		Transudate contained in the peritoneal cavity.
http://purl.obolibrary.org/obo/UBERON_0001359	cerebrospinal fluid	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord.
http://purl.obolibrary.org/obo/UBERON_0001460	arm	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The part of the forelimb extending from the shoulder to the autopod[cjm].
http://purl.obolibrary.org/obo/UBERON_0001485	knee joint	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The knee joint joins the thigh with the leg and consists of two articulations: one between the femur and tibia, and one between the femur and patella. It is the largest and most complicated joint in the human body. The knee is a mobile trocho-ginglymus (i.e. a pivotal hinge joint), which permits flexion and extension as well as a slight medial and lateral rotation[WP,unvetted].
http://purl.obolibrary.org/obo/UBERON_0001488	ankle joint	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A joint that connects the hindlimb autopod and zeugopod skeletons.
http://purl.obolibrary.org/obo/UBERON_0001530	common carotid artery plus branches	http://purl.obolibrary.org/obo/UBERON_0001637	artery		A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm].
http://purl.obolibrary.org/obo/UBERON_0001555	digestive tract	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A tube extending from the mouth to the anus.
http://purl.obolibrary.org/obo/UBERON_0001567	cheek	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A fleshy subdivision of one side of the face bounded by an eye, ear and the nose.
http://purl.obolibrary.org/obo/UBERON_0001577	facial muscle	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A muscle innervated by a facial nerve.
http://purl.obolibrary.org/obo/UBERON_0001826	nasal cavity mucosa	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The mucous membrane that lines the nasal cavity[MP].
http://purl.obolibrary.org/obo/UBERON_0001830	minor salivary gland	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		One of the smaller, largely mucus-secreting, exocrine glands of the oral cavity, consisting of the labial, buccal, molar, lingual, and palatine glands[MP].
http://purl.obolibrary.org/obo/UBERON_0001836	saliva	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		A fluid produced in the oral cavity by salivary glands, typically used in predigestion, but also in other functions.
http://purl.obolibrary.org/obo/UBERON_0001873	caudate nucleus	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species.
http://purl.obolibrary.org/obo/UBERON_0001874	putamen	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion.
http://purl.obolibrary.org/obo/UBERON_0001913	milk	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		An emulsion of fat globules within a fluid that is secreted by the mammary gland during lactation.
http://purl.obolibrary.org/obo/UBERON_0001968	semen	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		Organism substance that is composed of sperm cells suspended in seminal fluid.
http://purl.obolibrary.org/obo/UBERON_0001970	bile	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		Vital aqueous secretion of the liver that is formed by hepatocytes and modified down stream by absorptive and secretory properties of the bile duct epithelium.
http://purl.obolibrary.org/obo/UBERON_0001981	blood vessel	http://purl.obolibrary.org/obo/UBERON_0010000	multicellular anatomical structure		A vessel through which blood circulates in the body.
http://purl.obolibrary.org/obo/UBERON_0001988	feces	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		Portion of semisolid bodily waste discharged through the anus[MW,modified].
http://purl.obolibrary.org/obo/UBERON_0002032	areola	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Subdivision of breast which consists of skin, connective tissue and smooth muscle bundle and modified sebaceous glands and which surrounds the nipple.
http://purl.obolibrary.org/obo/UBERON_0002072	hypodermis	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP].
http://purl.obolibrary.org/obo/UBERON_0002097	skin of body	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The organ covering the body that consists of the dermis and epidermis.
http://purl.obolibrary.org/obo/UBERON_0002199	integument	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The dermis, epidermis and hypodermis.
http://purl.obolibrary.org/obo/UBERON_0002409	pericardial fluid	http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid		Transudate contained in the pericardial cavity.[FMA].
http://purl.obolibrary.org/obo/UBERON_0002415	tail	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		An external caudal extension of the body. In chordates, the tail is post-anal, in other animals the anus ends in the tail.
http://purl.obolibrary.org/obo/UBERON_0002465	lymphoid system	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The lymphatic system in vertebrates is a network of conduits that carry a clear fluid called lymph. It also includes the lymphoid tissue through which the lymph travels. Lymphoid tissue is found in many organs, particularly the lymph nodes, and in the lymphoid follicles associated with the digestive system such as the tonsils. The system also includes all the structures dedicated to the circulation and production of lymphocytes, which includes the spleen, thymus, bone marrow and the lymphoid tissue associated with the digestive system[WP].
http://purl.obolibrary.org/obo/UBERON_0002469	esophagus mucosa	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A mucosa that is part of a esophagus [Automatically generated definition].
http://purl.obolibrary.org/obo/UBERON_0002812	left cerebral hemisphere	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A cerebral hemisphere that is in the left side of a brain.
http://purl.obolibrary.org/obo/UBERON_0002813	right cerebral hemisphere	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A cerebral hemisphere that is in the right side of a brain.
http://purl.obolibrary.org/obo/UBERON_0003128	cranium	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Upper portion of the skull that excludes the mandible (when present in the organism).
http://purl.obolibrary.org/obo/UBERON_0003688	omentum	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A fold of peritoneum originating at the stomach and supporting the viscera.
http://purl.obolibrary.org/obo/UBERON_0004648	esophagus muscularis mucosa	http://purl.obolibrary.org/obo/UBERON_0000479	tissue		A muscularis mucosa that is part of a esophagus.
http://purl.obolibrary.org/obo/UBERON_0005022	mucosa of nasopharynx	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A mucosa that is part of a nasopharynx [Automatically generated definition].
http://purl.obolibrary.org/obo/UBERON_0005023	mucosa of oropharynx	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		A mucosa that is part of a oropharynx [Automatically generated definition].
http://purl.obolibrary.org/obo/UBERON_0005921	middle nasal concha	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		The medial surface of the labyrinth of ethmoid consists of a thin lamella, which descends from the under surface of the cribriform plate, and ends below in a free, convoluted margin, the middle nasal concha. It is rough, and marked above by numerous grooves, directed nearly vertically downward from the cribriform plate; they lodge branches of the olfactory nerves, which are distributed to the mucous membrane covering the superior nasal concha.
http://purl.obolibrary.org/obo/UBERON_0006314	bodily fluid	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not.
http://purl.obolibrary.org/obo/UBERON_0006538	respiratory system fluid/secretion	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		A portion of organism substance that secreted_by a respiratory system.
http://purl.obolibrary.org/obo/UBERON_0006618	atrium auricular region	http://purl.obolibrary.org/obo/UBERON_0000481	multi-tissue structure		A small conical pouch projections located on the upper anterior portion of each atrium of the heart.
http://purl.obolibrary.org/obo/UBERON_0007106	chorionic villus	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		One of the minute vascular projections of the fetal chorion that combines with maternal uterine tissue to form the placenta.
http://purl.obolibrary.org/obo/UBERON_0007109	meconium	http://purl.obolibrary.org/obo/UBERON_0001988	feces		A dark greenish mass that accumulates in the bowel during fetal life and is discharged shortly after birth.
http://purl.obolibrary.org/obo/UBERON_0007311	sputum	http://purl.obolibrary.org/obo/UBERON_0006538	respiratory system fluid/secretion		Matter ejected from the lungs, bronchi, and trachea, through the mouth.
http://purl.obolibrary.org/obo/UBERON_0007610	tibial artery	http://purl.obolibrary.org/obo/UBERON_0001637	artery		The anterior and posterior arteries created at the bifurcation of the popliteal artery. The anterior tibial artery begins at the lower border of the popliteus muscle and lies along the tibia at the distal part of the leg to surface superficially anterior to the ankle joint. Its branches are distributed throughout the leg, ankle, and pes. The posterior tibial artery begins at the lower border of the popliteus muscle, lies behind the tibia in the lower part of its course, and is found situated between the medial malleolus and the medial process of the calcaneal tuberosity. Its branches are distributed throughout the leg and foot.
http://purl.obolibrary.org/obo/UBERON_0008188	tendon of biceps brachii	http://purl.obolibrary.org/obo/UBERON_0000479	tissue		A tendon that attaches_to a biceps brachii.
http://purl.obolibrary.org/obo/UBERON_0010000	multicellular anatomical structure	http://purl.obolibrary.org/obo/UBERON_0000061	anatomical structure		An anatomical structure that has more than one cell as a part.
http://purl.obolibrary.org/obo/UBERON_0010414	omental fat pad	http://purl.obolibrary.org/obo/UBERON_0001013	adipose tissue		Encapsulated adipose tissue associated with the fold of peritoneal tissue that extends from the stomach to the posterior abdominal wall after associating with the transverse colon.
http://purl.obolibrary.org/obo/UBERON_0011011	brachioradialis	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Brachioradialis is a muscle of the forearm that acts to flex the forearm at the elbow. It is also capable of both pronation and supination, depending on the position of the forearm. It is attached to the distal styloid process of the radius by way of the brachioradialis tendon, and to the lateral supracondylar ridge of the humerus.
http://purl.obolibrary.org/obo/UBERON_0012168	umbilical cord blood	http://purl.obolibrary.org/obo/UBERON_0013755	arterial blood		Blood that remains in the placenta and in the attached umbilical cord after childbirth[WP].
http://purl.obolibrary.org/obo/UBERON_0013755	arterial blood	http://purl.obolibrary.org/obo/UBERON_0000178	blood		A blood that is part of a artery.
http://purl.obolibrary.org/obo/UBERON_0013756	venous blood	http://purl.obolibrary.org/obo/UBERON_0000178	blood		A blood that is part of a vein.
http://purl.obolibrary.org/obo/UBERON_0013757	capillary blood	http://purl.obolibrary.org/obo/UBERON_0000178	blood		A blood that is part of a capillary.
http://purl.obolibrary.org/obo/UBERON_3000016	anterior nasal wall	http://purl.obolibrary.org/obo/UBERON_0000465	material anatomical entity		Paired, vertical, and relatively straight plates that form the anterior limit of the nasal capsule.
http://purl.obolibrary.org/obo/PR_000003777	adiponectin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human ADIPOQ gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000003918	albumin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human ALB gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000004580	beta-2-microglobulin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human B2M gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000005794	ceruloplasmin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human CP gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000005897	C-reactive protein	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human CRP gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000007141	erythropoietin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human EPO gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000008457	beta-globin	http://purl.obolibrary.org/obo/PR_000000001	protein		A hemoglobin subunit that is a translation product of the human HBB gene, a 1:1 ortholog thereof, or pro-orthologs thereof.
http://purl.obolibrary.org/obo/PR_000008725	haptoglobin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human HP gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000029971	creatine kinase	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that contains a single ATP:guanido phosphotransferase N-terminal domain (Pfam:PF02807) followed by a single ATP:guanido phosphotransferase C-terminal catalytic domain (Pfam:PF00217).
http://purl.obolibrary.org/obo/OPL_0000232	parasite organism	http://purl.obolibrary.org/obo/OBI_0100026	organism		An organism living in, with, or on another organism in parasitism. Individual members of parasite species, such as Leishmania, Plasmodium, Trypanosoma, etc. are members of this class.
http://purl.obolibrary.org/obo/RO_0002533	sequence atomic unit	http://purl.obolibrary.org/obo/RO_0002532	sequentially ordered entity		Any individual unit of a collection of like units arranged in a linear order
http://purl.obolibrary.org/obo/RO_0002534	sequence bearer	http://purl.obolibrary.org/obo/RO_0002532	sequentially ordered entity		Any entity that can be divided into parts such that each part is an atomical unit of a sequence
http://purl.obolibrary.org/obo/CHEBI_166899	globulin type	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		One of the major classifications of proteins, which may be further divided into the euglobulins and the pseudoglobulins. The former group is insoluble in water but soluble in saline solutions and may be precipitated in water that has been half-saturated with a salt such as ammonium sulfate. The latter group is soluble in water and has properties that resemble those of the true globulins. Globulins are an important source of protein in seed plants and are found in minute amounts in cereals. Globulins found in animal fluids are enzymes, antibodies, and fibrous and contractile proteins usually contained in the blood plasma.
http://purl.obolibrary.org/obo/OBI_0003327	image data set	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set that is comprised of multidimensional structured measurements and metadata required for a morphological representation of an entity. An image data set can be the source from which an image (such as a 2D image using pixels or a 3D image using voxels) is produced.
http://purl.obolibrary.org/obo/OBI_0003325	high throughput multiplexed assay measuring binding of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_1110126	assay measuring binding of a MHC:ligand complex		A MHC ligand assay that detects the binding of a ligand to an MHC molecule using a high throughput multiplexed assay.
http://purl.obolibrary.org/obo/OBI_0003547	liquid chromatography	http://purl.obolibrary.org/obo/OBI_0600046	preparative chromatography		A preparative chromatography in which material components are separated in a liquid solution.
http://purl.obolibrary.org/obo/OBI_0003654	overnight fasting	http://purl.obolibrary.org/obo/OBI_0003653	fasting		A fasting with a duration of 8–12 hours, typically occurring overnight.
http://purl.obolibrary.org/obo/OBI_0003715	vital sign assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay of a organism to measure basic physiological functions such as breathing, pulse, etc. (phylum bilateral).
http://purl.obolibrary.org/obo/CHEBI_15377	water	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms
http://purl.obolibrary.org/obo/CHEBI_15422	ATP	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An adenosine 5'-phosphate in which the 5'-phosphate is a triphosphate group. It is involved in the transportation of chemical energy during metabolic pathways.
http://purl.obolibrary.org/obo/CHEBI_28689	dehydroepiandrosterone	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.
http://purl.obolibrary.org/obo/CHEBI_16113	cholesterol	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		A cholestanoid consisting of cholestane having a double bond at the 5,6-position as well as a 3beta-hydroxy group.
http://purl.obolibrary.org/obo/CHEBI_28001	vancomycin	http://purl.obolibrary.org/obo/CHEBI_16670	peptide		A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile.
http://purl.obolibrary.org/obo/CHEBI_53526	tritiated thymidine	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		Thymidine linked to the radioisotope tritium. Used to label DNA in the study of cellular and viral DNA synthesis.
http://purl.obolibrary.org/obo/SO_0000235	TF_binding_site	http://purl.obolibrary.org/obo/SO_0005836	regulatory_region		A DNA site where a transcription factor binds.
http://purl.obolibrary.org/obo/SO_0001410	experimental_feature	http://purl.obolibrary.org/obo/SO_0000001	region		A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer.
http://purl.obolibrary.org/obo/SO_0005836	regulatory_region	http://purl.obolibrary.org/obo/SO_0000001	region		A region of sequence that is involved in the control of a biological process.
http://purl.obolibrary.org/obo/OMRSE_00000012	health care provider role	http://purl.obolibrary.org/obo/BFO_0000023	role		A human health care role inhering in an organization or human being that is realized by a process of providing health care services to an organism.
http://purl.obolibrary.org/obo/OMRSE_00000054	hospital role	http://purl.obolibrary.org/obo/BFO_0000023	role		A healthcare provider role that inheres in an organization and is realized by providing inpatient care.
http://purl.obolibrary.org/obo/OMRSE_00000056	hospital organization	http://purl.obolibrary.org/obo/OBI_0000245	organization		An organization that is the bearer of a hospital role.
http://purl.obolibrary.org/obo/COB_0000080	complex of molecules	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A complex of two or more molecular entities that are not covalently bound.
http://purl.obolibrary.org/obo/OBI_0003316	ELISA measuring epitope specific amphiregulin production by T cells	http://purl.obolibrary.org/obo/OBI_0003315	assay measuring epitope specific amphiregulin production by T cells		An enzyme-linked immunosorbent assay that detects amphiregulin production by T cells.
http://purl.obolibrary.org/obo/OBI_0003337	resting state functional magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003336	functional magnetic resonance image data set		A type of functional MRI in which the participant is not given a task, but just rests during acquisision
http://purl.obolibrary.org/obo/OBI_0003416	mid-upper arm circumference datum	http://purl.obolibrary.org/obo/IAO_0000408	length measurement datum		A length measurement datum that is the specified output of an assay measuring the length around an upper arm, taken midway along the upper arm.
http://purl.obolibrary.org/obo/OBI_0003655	fasted	http://purl.obolibrary.org/obo/PATO_0001995	organismal quality		An organismal quality that inheres in an organism that has completed a fasting process, and which ceases to inhere in that organism once that organism drinks a liquid other than water or eats.
http://purl.obolibrary.org/obo/OBI_0003720	cell differentiation assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that monitors the differentiation stage of cells in culture.
http://purl.obolibrary.org/obo/OBI_0003719	respiratory assay	http://purl.obolibrary.org/obo/OBI_0003715	vital sign assay		A vital sign assay that measures the quality of respiration / respiratory system of an organism
http://purl.obolibrary.org/obo/OBI_0000969	dose specification	http://purl.obolibrary.org/obo/IAO_0000033	directive information entity		a directive information entity that describes the dose that will be administered to a target
http://purl.obolibrary.org/obo/OBI_0001509	Edman degradation assay measuring MHC ligand processing and presentation	http://purl.obolibrary.org/obo/OBI_1110125	assay measuring MHC ligand processing and presentation		A MHC ligand processing and presentation assay that uses Edman degradation to identify the eluted ligands
http://purl.obolibrary.org/obo/OBI_0003145	assay measuring quantitative binding of a MHC:ligand complex	http://purl.obolibrary.org/obo/OBI_1110126	assay measuring binding of a MHC:ligand complex		An assay that detects the binding of a MHC molecule with a ligand, and produces a quantitative measurement of the binding as an output.
http://purl.obolibrary.org/obo/OBI_0003146	assay measuring quantitative binding of an antigen:antibody complex	http://purl.obolibrary.org/obo/OBI_1110127	assay measuring binding of a B cell epitope:antibody complex		An assay that detects the binding of an antigen with an antibody, and produces a quantitative measurement of the binding as an output.
http://purl.obolibrary.org/obo/PATO_0070060	quality of interaction of a substance with electromagnetic radiation	http://purl.obolibrary.org/obo/PATO_0002198	quality of a substance		A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength.
http://purl.obolibrary.org/obo/OBI_0003658	ring trial design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design with the objective of establishing the reproducibility of an experimental approach by performing experiments in different laboratories under the same conditions and comparing the experimental outcomes.
http://purl.obolibrary.org/obo/OBI_0003693	observational investigation	http://purl.obolibrary.org/obo/OBI_0000066	investigation		An investigation in which subjects are monitored in the absence of any active intervention by experimentalists.
http://purl.obolibrary.org/obo/OBI_0002930	light trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that uses light as an attractant.
http://purl.obolibrary.org/obo/OBI_0002565	adapter-sequence trimming	http://purl.obolibrary.org/obo/OBI_0002585	sequence trimming		A data transformation in which adapter sequences at the end of a molecular sequence are cut (removed).
http://purl.obolibrary.org/obo/OBI_0002998	arthropod collection process with automated identification	http://purl.obolibrary.org/obo/OBI_0002913	arthropod specimen collection process		An arthropod specimen collection process that involves a device that produces data specifying the types of arthropod collected.
http://purl.obolibrary.org/obo/OBI_0002999	gravid female arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0002913	arthropod specimen collection process		An arthropod specimen collection process that has the objective of collecting gravid female arthropods.
http://purl.obolibrary.org/obo/OBI_0003000	resting flight-capable arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0002913	arthropod specimen collection process		An arthropod specimen collection process that occurs while an arthropod that is capable of flight is resting outdoors during a period of inactivity.
http://purl.obolibrary.org/obo/OBI_0003001	daytime arthropod specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002912	arthropod specimen collection by aspiration		An arthropod specimen collection by aspiration that occurs in the daytime.
http://purl.obolibrary.org/obo/OBI_0003002	arthropod resting in human house specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002912	arthropod specimen collection by aspiration		An arthropod specimen collection by aspiration that catches specimens resting inside a human house.
http://purl.obolibrary.org/obo/OBI_0003004	flying adult arthropod collection process by passive interception	http://purl.obolibrary.org/obo/OBI_0002904	adult arthropod specimen collection process		An adult arthropod specimen collection process that has the objective of collecting arthropods capable of flight, through the use of a barrier trap.
http://purl.obolibrary.org/obo/OBI_0003005	device for collection of resting adult arthropods	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is designed to provide a solid surface that is attractive to an arthropod as a place to rest during a period of inactivity.
http://purl.obolibrary.org/obo/OBI_0003006	well net for arthropod immatures	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is designed for the collection of arthropod larvae or pupae from water and consists of a conical net.
http://purl.obolibrary.org/obo/OBI_0003008	trap for emerging adult arthropods	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that is designed to trap an arthropod as it emerges from water at the beginning of its adult stage.
http://purl.obolibrary.org/obo/OBI_0003030	oligonucleotide primer set	http://purl.obolibrary.org/obo/CHEBI_33696	nucleic acid		A processed material that consists of oligonucleotides that bear a primer role.
http://purl.obolibrary.org/obo/OBI_0003079	temperature measurement datum	http://purl.obolibrary.org/obo/IAO_0000032	scalar measurement datum		A scalar measurement datum that is the result of measuring temperature.
http://purl.obolibrary.org/obo/OBI_0003290	mosquito membrane feeding assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that evaluates host-to-mosquito transmission of a parasite organism by feeding a specimen of host blood infected with the parasite organism to a collection of mosquitoes through a mosquito membrane feeding device and, after a given time, dissecting the mosquitoes and counting the number of parasite organisms within them.
http://purl.obolibrary.org/obo/OBI_0003467	in vivo assay measuring B cell epitope specific protection from other challenge	http://purl.obolibrary.org/obo/OBI_0001710	in vivo assay measuring B cell epitope specific protection from challenge		An in vivo assay measuring B cell epitope specific protection from a challenge other than pathogen, infection, or tumor.
http://purl.obolibrary.org/obo/OBI_0003587	cell culture assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has cell culture as an input.
http://purl.obolibrary.org/obo/OBI_0003661	in vitro CRISPR screen using flow cytometry	http://purl.obolibrary.org/obo/OBI_0003659	in vitro CRISPR screen assay		An in vitro CRISPR screen assay that uses flow cytometry to detect induced changes in gene expression of the targeted genes.
http://purl.obolibrary.org/obo/OBI_0003659	in vitro CRISPR screen assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		An assay in which cells expressing a Cas system are infected with a library of guide RNAs with the intent of causing a perturbation at the target of the guide RNAs.
http://purl.obolibrary.org/obo/OBI_0003721	cell based DNA damage assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures DNA damage in cells.
http://purl.obolibrary.org/obo/GO_0000785	chromatin	http://purl.obolibrary.org/obo/GO_0005575	cellular_component		The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
http://purl.obolibrary.org/obo/GO_0001046	core promoter sequence-specific DNA binding	http://purl.obolibrary.org/obo/GO_0043565	sequence-specific DNA binding		Binding to a sequence of DNA that is part of a core promoter region. The core promoter is composed of the transcription start site and binding sites for the RNA polymerase and the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
http://purl.obolibrary.org/obo/GO_0001172	RNA-templated transcription	http://purl.obolibrary.org/obo/GO_0009987	cellular process		The synthesis of an RNA transcript from an RNA template.
http://purl.obolibrary.org/obo/GO_0001508	action potential	http://purl.obolibrary.org/obo/GO_0008150	biological process		A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
http://purl.obolibrary.org/obo/GO_0001788	antibody-dependent cellular cytotoxicity	http://purl.obolibrary.org/obo/GO_0008150	biological process		Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
http://purl.obolibrary.org/obo/GO_0001806	type IV hypersensitivity	http://purl.obolibrary.org/obo/GO_0002524	hypersensitivity		An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.
http://purl.obolibrary.org/obo/GO_0001816	cytokine production	http://purl.obolibrary.org/obo/GO_0008150	biological process		The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0001906	cell killing	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
http://purl.obolibrary.org/obo/GO_0001913	T cell mediated cytotoxicity	http://purl.obolibrary.org/obo/GO_0001906	cell killing		The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
http://purl.obolibrary.org/obo/GO_0001964	startle response	http://purl.obolibrary.org/obo/GO_0050905	neuromuscular process		An action or movement due to the application of a sudden unexpected stimulus.
http://purl.obolibrary.org/obo/GO_0002027	regulation of heart rate	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process that modulates the frequency or rate of heart contraction.
http://purl.obolibrary.org/obo/GO_0002250	adaptive immune response	http://purl.obolibrary.org/obo/GO_0006955	immune response		An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
http://purl.obolibrary.org/obo/GO_0002367	cytokine production involved in immune response	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0002507	tolerance induction	http://purl.obolibrary.org/obo/GO_0008150	biological process		A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.
http://purl.obolibrary.org/obo/GO_0002514	B cell tolerance induction	http://purl.obolibrary.org/obo/GO_0002507	tolerance induction		A process involving any mechanism for tolerance induction in B cells.
http://purl.obolibrary.org/obo/GO_0002517	T cell tolerance induction	http://purl.obolibrary.org/obo/GO_0002507	tolerance induction		A process involving any mechanism for tolerance induction in T cells.
http://purl.obolibrary.org/obo/GO_0002524	hypersensitivity	http://purl.obolibrary.org/obo/GO_0008150	biological process		An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
http://purl.obolibrary.org/obo/GO_0002534	cytokine production involved in inflammatory response	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0003016	respiratory system process	http://purl.obolibrary.org/obo/GO_0008150	biological process		A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.
http://purl.obolibrary.org/obo/GO_0003094	glomerular filtration	http://purl.obolibrary.org/obo/GO_0008150	biological process		The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.
http://purl.obolibrary.org/obo/GO_0003674	gene product or complex activity	http://purl.obolibrary.org/obo/BFO_0000015	process		A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs.
http://purl.obolibrary.org/obo/GO_0003823	antigen binding	http://purl.obolibrary.org/obo/GO_0003674	gene product or complex activity		Binding to an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen. Antigen binding by an MHC protein complex allows the antigen to be displayed to a T cell or NK cell.
http://purl.obolibrary.org/obo/GO_0003824	catalytic activity	http://purl.obolibrary.org/obo/GO_0003674	gene product or complex activity		Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
http://purl.obolibrary.org/obo/GO_0003939	L-iditol 2-dehydrogenase (NAD+) activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+. Acts on a number of sugar alcohols, including (but not limited to) L-iditol, D-glucitol, D-xylitol, and D-galactitol.
http://purl.obolibrary.org/obo/GO_0003964	RNA-directed DNA polymerase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.
http://purl.obolibrary.org/obo/GO_0003990	acetylcholinesterase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: acetylcholine + H2O = choline + acetate.
http://purl.obolibrary.org/obo/GO_0003997	acyl-CoA oxidase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: a 2,3-saturated acyl-CoA + O2 = a (2E)-enoyl-CoA + H2O2.
http://purl.obolibrary.org/obo/GO_0004021	L-alanine:2-oxoglutarate aminotransferase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
http://purl.obolibrary.org/obo/GO_0004035	alkaline phosphatase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: a phosphate monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
http://purl.obolibrary.org/obo/GO_0004069	L-aspartate:2-oxoglutarate aminotransferase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
http://purl.obolibrary.org/obo/GO_0004104	cholinesterase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.
http://purl.obolibrary.org/obo/GO_0004111	creatine kinase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H+.
http://purl.obolibrary.org/obo/GO_0004353	glutamate dehydrogenase [NAD(P)+] activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.
http://purl.obolibrary.org/obo/GO_0004364	glutathione transferase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
http://purl.obolibrary.org/obo/GO_0004448	isocitrate dehydrogenase [NAD(P)+] activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: isocitrate + NAD(P)+ = 2-oxoglutarate + CO2 + NAD(P)H.
http://purl.obolibrary.org/obo/GO_0004457	lactate dehydrogenase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.
http://purl.obolibrary.org/obo/GO_0004540	RNA nuclease activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
http://purl.obolibrary.org/obo/GO_0005694	chromosome	http://purl.obolibrary.org/obo/GO_0005575	cellular_component		A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
http://purl.obolibrary.org/obo/GO_0005739	mitochondrion	http://purl.obolibrary.org/obo/GO_0043227	membrane-bounded organelle		A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
http://purl.obolibrary.org/obo/GO_0006260	DNA replication	http://purl.obolibrary.org/obo/GO_0008150	biological process		The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by the origin recognition complex, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
http://purl.obolibrary.org/obo/GO_0006909	phagocytosis	http://purl.obolibrary.org/obo/GO_0008150	biological process		A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
http://purl.obolibrary.org/obo/GO_0006955	immune response	http://purl.obolibrary.org/obo/GO_0050896	response to stimulus		Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
http://purl.obolibrary.org/obo/GO_0006974	DNA damage response	http://purl.obolibrary.org/obo/GO_0050896	response to stimulus		Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
http://purl.obolibrary.org/obo/GO_0007049	cell cycle	http://purl.obolibrary.org/obo/GO_0008150	biological process		The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
http://purl.obolibrary.org/obo/GO_0008150	biological process	http://purl.obolibrary.org/obo/BFO_0000015	process		A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence.
http://purl.obolibrary.org/obo/GO_0008217	regulation of blood pressure	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
http://purl.obolibrary.org/obo/GO_0008283	cell population proliferation	http://purl.obolibrary.org/obo/GO_0008150	biological process		The multiplication or reproduction of cells, resulting in the expansion of a cell population.
http://purl.obolibrary.org/obo/GO_0009987	cellular process	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
http://purl.obolibrary.org/obo/GO_0010467	gene expression	http://purl.obolibrary.org/obo/GO_0008150	biological process		The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes.
http://purl.obolibrary.org/obo/GO_0016064	immunoglobulin mediated immune response	http://purl.obolibrary.org/obo/GO_0008150	biological process		An immune response mediated by immunoglobulins, whether cell-bound or in solution.
http://purl.obolibrary.org/obo/GO_0016301	kinase activity	http://purl.obolibrary.org/obo/GO_0003674	gene product or complex activity		Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
http://purl.obolibrary.org/obo/GO_0019107	myristoyltransferase activity	http://purl.obolibrary.org/obo/GO_0003674	gene product or complex activity		Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule.
http://purl.obolibrary.org/obo/GO_0019882	antigen processing and presentation	http://purl.obolibrary.org/obo/GO_0008150	biological process		The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
http://purl.obolibrary.org/obo/GO_0022414	reproductive process	http://purl.obolibrary.org/obo/GO_0008150	biological process		A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
http://purl.obolibrary.org/obo/GO_0030097	hemopoiesis	http://purl.obolibrary.org/obo/GO_0008150	biological process		The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
http://purl.obolibrary.org/obo/GO_0030154	cell differentiation	http://purl.obolibrary.org/obo/GO_0048869	cellular developmental process		The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
http://purl.obolibrary.org/obo/GO_0034061	DNA polymerase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1).
http://purl.obolibrary.org/obo/GO_0042098	T cell proliferation	http://purl.obolibrary.org/obo/GO_0008283	cell population proliferation		The expansion of a T cell population by cell division. Follows T cell activation.
http://purl.obolibrary.org/obo/GO_0042110	T cell activation	http://purl.obolibrary.org/obo/GO_0008150	biological process		The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
http://purl.obolibrary.org/obo/GO_0042575	DNA polymerase complex	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.
http://purl.obolibrary.org/obo/GO_0045087	innate immune response	http://purl.obolibrary.org/obo/GO_0006955	immune response		Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
http://purl.obolibrary.org/obo/GO_0048869	cellular developmental process	http://purl.obolibrary.org/obo/GO_0008150	biological process		A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
http://purl.obolibrary.org/obo/GO_0048871	multicellular organismal-level homeostasis	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.
http://purl.obolibrary.org/obo/GO_0050905	neuromuscular process	http://purl.obolibrary.org/obo/GO_0008150	biological process		Any process pertaining to the functions of the nervous and muscular systems of an organism.
http://purl.obolibrary.org/obo/GO_0051276	chromosome organization	http://purl.obolibrary.org/obo/GO_0008150	biological process		A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
http://purl.obolibrary.org/obo/GO_0052689	carboxylic ester hydrolase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the hydrolysis of a carboxylic ester bond.
http://purl.obolibrary.org/obo/GO_0019814	immunoglobulin complex	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
http://purl.obolibrary.org/obo/GO_0019815	B cell receptor complex	http://purl.obolibrary.org/obo/OBI_1110022	adaptive immune receptor		An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
http://purl.obolibrary.org/obo/GO_0030041	actin filament polymerization	http://purl.obolibrary.org/obo/GO_0008150	biological process		Assembly of actin filaments by the addition of actin monomers to a filament.
http://purl.obolibrary.org/obo/GO_0032601	connective tissue growth factor production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032602	chemokine production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
http://purl.obolibrary.org/obo/GO_0032604	granulocyte macrophage colony-stimulating factor production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032605	hepatocyte growth factor production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032606	type I interferon production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
http://purl.obolibrary.org/obo/GO_0032607	interferon-alpha production	http://purl.obolibrary.org/obo/GO_0032606	type I interferon production		The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032608	interferon-beta production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032609	type II interferon production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.
http://purl.obolibrary.org/obo/GO_0032610	interleukin-1 alpha production	http://purl.obolibrary.org/obo/GO_0032612	interleukin-1 production		The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032611	interleukin-1 beta production	http://purl.obolibrary.org/obo/GO_0032612	interleukin-1 production		The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032612	interleukin-1 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032613	interleukin-10 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032614	interleukin-11 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032615	interleukin-12 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032616	interleukin-13 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032617	obsolete interleukin-14 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		OBSOLETE. The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032618	interleukin-15 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032619	interleukin-16 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032620	interleukin-17 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032621	interleukin-18 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032622	interleukin-19 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032623	interleukin-2 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032624	interleukin-20 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032625	interleukin-21 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032626	interleukin-22 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032627	interleukin-23 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032628	interleukin-24 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032629	interleukin-25 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032630	interleukin-26 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032631	interleukin-27 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032632	interleukin-3 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032633	interleukin-4 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032634	interleukin-5 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032635	interleukin-6 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032636	interleukin-7 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032637	interleukin-8 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032638	interleukin-9 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032639	TRAIL production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032905	transforming growth factor beta1 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032906	transforming growth factor beta2 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0032907	transforming growth factor beta3 production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.
http://purl.obolibrary.org/obo/GO_0043227	membrane-bounded organelle	http://purl.obolibrary.org/obo/GO_0005575	cellular_component		Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
http://purl.obolibrary.org/obo/GO_0071604	transforming growth factor beta production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.
http://purl.obolibrary.org/obo/GO_0071706	tumor necrosis factor superfamily cytokine production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0034343	type III interferon production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.
http://purl.obolibrary.org/obo/GO_0035393	chemokine (C-X-C motif) ligand 9 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0035397	helper T cell enhancement of adaptive immune response	http://purl.obolibrary.org/obo/GO_0002250	adaptive immune response		Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.
http://purl.obolibrary.org/obo/GO_0035398	helper T cell enhancement of T cell mediated immune response	http://purl.obolibrary.org/obo/GO_0035397	helper T cell enhancement of adaptive immune response		Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.
http://purl.obolibrary.org/obo/GO_0035399	helper T cell enhancement of B cell mediated immune response	http://purl.obolibrary.org/obo/GO_0035397	helper T cell enhancement of adaptive immune response		Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.
http://purl.obolibrary.org/obo/GO_0035746	granzyme A production	http://purl.obolibrary.org/obo/GO_0008150	biological process		The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0035944	perforin production	http://purl.obolibrary.org/obo/GO_0008150	biological process		The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0036262	granulysin production	http://purl.obolibrary.org/obo/GO_0008150	biological process		The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0036392	chemokine (C-C motif) ligand 20 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0042101	T cell receptor complex	http://purl.obolibrary.org/obo/OBI_1110022	adaptive immune receptor		A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.
http://purl.obolibrary.org/obo/GO_0042605	peptide antigen binding	http://purl.obolibrary.org/obo/GO_0003823	antigen binding		Binding to an antigen peptide.
http://purl.obolibrary.org/obo/GO_0043316	cytotoxic T cell degranulation	http://purl.obolibrary.org/obo/GO_0001906	cell killing		The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
http://purl.obolibrary.org/obo/GO_0044807	macrophage migration inhibitory factor production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0044808	oncostatin M production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0044809	chemokine (C-C motif) ligand 17 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0097087	interleukin-17A production	http://purl.obolibrary.org/obo/GO_0032620	interleukin-17 production		The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0097088	interleukin-17F production	http://purl.obolibrary.org/obo/GO_0032620	interleukin-17 production		The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0097278	complement-dependent cytotoxicity	http://purl.obolibrary.org/obo/GO_0001906	cell killing		Cell killing caused by the membrane attack complex formed following complement activation.
http://purl.obolibrary.org/obo/GO_0097280	histamine secretion mediated by immunoglobulin	http://purl.obolibrary.org/obo/GO_0006955	immune response		Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.
http://purl.obolibrary.org/obo/GO_0097281	immune complex formation	http://purl.obolibrary.org/obo/GO_0016064	immunoglobulin mediated immune response		The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.
http://purl.obolibrary.org/obo/GO_0097282	immunoglobulin-mediated neutralization	http://purl.obolibrary.org/obo/GO_0016064	immunoglobulin mediated immune response		The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.
http://purl.obolibrary.org/obo/GO_0097388	chemokine (C-C motif) ligand 19 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0097389	chemokine (C-C motif) ligand 21 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0097390	chemokine (C-X-C motif) ligand 12 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0097391	chemokine (C-X-C motif) ligand 13 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0097392	chemokine (C-X-C motif) ligand 16 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/PR_000003015	prostate-specific antigen	http://purl.obolibrary.org/obo/PR_000000001	protein		A trypsin that is a translation product of the human KLK3 gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000027247	cytosolic creatine kinase complex, MB-type	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A cytosolic creatine kinase complex that is a heterodimer of a B-type subunit and an M-type subunit.
http://purl.obolibrary.org/obo/ENVO_01000254	environmental system	http://purl.obolibrary.org/obo/RO_0002577	system		A system which has the disposition to environ one or more material entities.
http://purl.obolibrary.org/obo/RO_0002577	system	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity consisting of multiple components that are causally integrated.
http://purl.obolibrary.org/obo/OBI_0002145	antigen specific antibodies assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the presence or amount of antibodies to a specified antigen.
http://purl.obolibrary.org/obo/PATO_0070044	anatomical structure quality	http://purl.obolibrary.org/obo/PATO_0001241	physical object quality		A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components.
http://purl.obolibrary.org/obo/OBI_0003595	nasal lavage fluid	http://purl.obolibrary.org/obo/OBI_0003666	lavage fluid specimen		A specimen collected through nasal cavity lavage that contains the reagents used to for the lavage process, organisms, cells, cellular secretions, and other biomaterials present in the nasal cavity space.
http://purl.obolibrary.org/obo/OBI_0003600	hypertension grade	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification		A categorical value specification that indicates the severity of hypertension.
http://purl.obolibrary.org/obo/OBI_0003666	lavage fluid specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen obtained through a lavage process which includes fluid in addition to cells and/or cellular secretions.
http://purl.obolibrary.org/obo/GO_0008228	opsonization	http://purl.obolibrary.org/obo/GO_0006909	phagocytosis		The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.
http://purl.obolibrary.org/obo/GO_0008253	5'-nucleotidase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
http://purl.obolibrary.org/obo/GO_0010573	vascular endothelial growth factor production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0016231	beta-N-acetylglucosaminidase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.
http://purl.obolibrary.org/obo/GO_0019904	protein domain specific binding	http://purl.obolibrary.org/obo/OBI_0001588	binding		Binding to a specific domain of a protein.
http://purl.obolibrary.org/obo/GO_0043565	sequence-specific DNA binding	http://purl.obolibrary.org/obo/OBI_0001588	binding		Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
http://purl.obolibrary.org/obo/GO_0070358	actin polymerization-dependent cell motility	http://purl.obolibrary.org/obo/GO_0008150	biological process		A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.
http://purl.obolibrary.org/obo/GO_0071605	monocyte chemotactic protein-1 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071606	chemokine (C-C motif) ligand 4 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071607	macrophage inflammatory protein-1 gamma production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071608	macrophage inflammatory protein-1 alpha production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071609	chemokine (C-C motif) ligand 5 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071610	chemokine (C-C motif) ligand 1 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071611	granulocyte colony-stimulating factor production	http://purl.obolibrary.org/obo/GO_0001816	cytokine production		The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071612	IP-10 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071613	granzyme B production	http://purl.obolibrary.org/obo/GO_0008150	biological process		The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0071735	IgG immunoglobulin complex	http://purl.obolibrary.org/obo/GO_0019814	immunoglobulin complex		A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
http://purl.obolibrary.org/obo/GO_0071742	IgE immunoglobulin complex	http://purl.obolibrary.org/obo/GO_0019814	immunoglobulin complex		A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
http://purl.obolibrary.org/obo/GO_0071745	IgA immunoglobulin complex	http://purl.obolibrary.org/obo/GO_0019814	immunoglobulin complex		A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
http://purl.obolibrary.org/obo/GO_0071753	IgM immunoglobulin complex	http://purl.obolibrary.org/obo/GO_0019814	immunoglobulin complex		A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
http://purl.obolibrary.org/obo/GO_0071924	chemokine (C-C motif) ligand 22 production	http://purl.obolibrary.org/obo/GO_0032602	chemokine production		The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/GO_0072535	tumor necrosis factor (ligand) superfamily member 11 production	http://purl.obolibrary.org/obo/GO_0071706	tumor necrosis factor superfamily cytokine production		The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
http://purl.obolibrary.org/obo/PR_000009758	leptin	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human LEP gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000013429	parathyroid hormone	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human PTH gene or a 1:1 ortholog thereof.
http://purl.obolibrary.org/obo/PR_000036824	NS1	http://purl.obolibrary.org/obo/PR_000000001	protein		A dengue virus genome polyprotein proteolytic cleavage product that is the N-terminal most non-structural protein within the dengue virus genome polyprotein. Example: UniProtKB:P29990, 776-1127, Asn-905/Asn-982, MOD:00160.
http://purl.obolibrary.org/obo/OBI_0002650	biopsy	http://purl.obolibrary.org/obo/OBI_0600005	collecting specimen from organism		A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive.
http://purl.obolibrary.org/obo/OBI_0002653	ultrasound-guided needle biopsy	http://purl.obolibrary.org/obo/OBI_0002651	image guided biopsy		A needle biopsy guided by ultrasound visualization.
http://purl.obolibrary.org/obo/OBI_0002654	needle biopsy	http://purl.obolibrary.org/obo/OBI_0002650	biopsy		A biopsy that uses a hollow needle to extract cells.
http://purl.obolibrary.org/obo/OBI_0002662	bone marrow biopsy	http://purl.obolibrary.org/obo/OBI_0002650	biopsy		A biopsy where a small amount of bone and a small amount of fluid and bone marrow are collected.
http://purl.obolibrary.org/obo/OBI_0002679	vacuum-assisted biopsy needle	http://purl.obolibrary.org/obo/OBI_0000436	needle		A core biopsy needle integrated with a vacuum system which facilitates the collection of specimen material.
http://purl.obolibrary.org/obo/OBI_0002746	induced sputum specimen	http://purl.obolibrary.org/obo/OBI_0002508	sputum specimen		A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution.
http://purl.obolibrary.org/obo/OBI_0002747	passage process	http://purl.obolibrary.org/obo/OBI_0000094	material processing		A material processing that consists of first growing an organism in an environmental system and then removing the organism to be grown in another environmental system, a process which may be repeated with the objective of altering the organism or increasing its number.
http://purl.obolibrary.org/obo/OBI_0002748	passage history record	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is about the sequence of environmental systems in each of which is grown an organism in a passage process.
http://purl.obolibrary.org/obo/OBI_0002754	cDNA library	http://purl.obolibrary.org/obo/OBI_0000047	processed material		A collection of DNA molecules with sequences complementary to a specified set of mRNA molecules and commonly developed by enzymatic reverse transcription.
http://purl.obolibrary.org/obo/OBI_0002756	ordinal value specification	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification		A categorical value specification in which the available categories were created with an explicit order.
http://purl.obolibrary.org/obo/OBI_0002760	metatranscriptome sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay		An RNA-seq assay that determines the RNA sequence of microbial transcripts from a microbioal community of mixed species from a given microbiome.
http://purl.obolibrary.org/obo/OBI_0002766	cytokine assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay to study presence, concentration, or amount of cytokines.
http://purl.obolibrary.org/obo/OBI_0002767	amplicon sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay		A sequencing assay in which a DNA or RNA input molecule is amplified by PCR and the product sequenced.
http://purl.obolibrary.org/obo/OBI_0002768	whole virome sequencing assay	http://purl.obolibrary.org/obo/OBI_0002623	whole metagenome sequencing assay		A whole metagenome sequencing assay that intends to provide information on multiple genome sequences from different viruses present in the same input sample.
http://purl.obolibrary.org/obo/OBI_0002769	karyotype information	http://purl.obolibrary.org/obo/OBI_0001404	genetic characteristics information		A genetic characteristics information that is about the number and appearance of chromosomes in the nucleus of an eukaryotic cell.
http://purl.obolibrary.org/obo/OBI_0002770	partial karyotype information	http://purl.obolibrary.org/obo/OBI_0002769	karyotype information		A karyotype information that is about the structural variation of partial genome rather than whole genome.
http://purl.obolibrary.org/obo/OBI_0002771	full karyotype information	http://purl.obolibrary.org/obo/OBI_0002769	karyotype information		A karyotype information that is about the structural variation of the whole genome.
http://purl.obolibrary.org/obo/OBI_0002772	presence or over-threshold value specification	http://purl.obolibrary.org/obo/OBI_0002756	ordinal value specification		An ordinal value specification that indicates that either 
a) an analyte or mesaurand is present in an evaluant, or 
b) that the amount of analyte/measurand detected is over some predetermined threshold.
http://purl.obolibrary.org/obo/OBI_0002774	platelet-poor plasma specimen	http://purl.obolibrary.org/obo/OBI_0100016	blood plasma specimen		A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter.
http://purl.obolibrary.org/obo/OBI_0002775	platelet-poor plasma preparation process	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		A material component separation process in which (1) whole blood is first centrifuged to separate red blood cells from blood plasma, which forms the supernatant, and (2) the blood plasma is then centrifuged to separate platelets from the plasm.
http://purl.obolibrary.org/obo/OBI_2000000	uterine cervix specimen	http://purl.obolibrary.org/obo/OBI_0002553	uterus specimen		A specimen that is derived from some uterine cervix
http://purl.obolibrary.org/obo/OBI_2000001	urethra specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from some urethra
http://purl.obolibrary.org/obo/OBI_2000002	cervical mucus specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from some cervical mucus
http://purl.obolibrary.org/obo/OBI_2000003	throat specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from some throat
http://purl.obolibrary.org/obo/OBI_2000004	eye specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from some eye
http://purl.obolibrary.org/obo/OBI_2000005	respiratory system specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from some respiratory system
http://purl.obolibrary.org/obo/OBI_2000006	upper respiratory tract specimen	http://purl.obolibrary.org/obo/OBI_2000005	respiratory system specimen		A specimen that is derived from some upper respiratory tract
http://purl.obolibrary.org/obo/OBI_2000007	nasopharynx specimen	http://purl.obolibrary.org/obo/OBI_2000006	upper respiratory tract specimen		A specimen that is derived from some nasopharynx
http://purl.obolibrary.org/obo/OBI_2000008	semen specimen	http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen		A specimen that is derived from some semen
http://purl.obolibrary.org/obo/OBI_2000009	bodily fluid specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from some bodily fluid
http://purl.obolibrary.org/obo/OBI_2000010	chorionic villus specimen	http://purl.obolibrary.org/obo/OBI_0002513	placenta specimen		A specimen that is derived from some chorionic villus
http://purl.obolibrary.org/obo/OBI_2000011	meconium specimen	http://purl.obolibrary.org/obo/OBI_0002503	feces specimen		A specimen that is derived from some meconium
http://purl.obolibrary.org/obo/OBI_2000012	umbilical cord blood specimen	http://purl.obolibrary.org/obo/OBI_2000013	arterial blood specimen		A specimen that is derived from some umbilical cord blood
http://purl.obolibrary.org/obo/OBI_2000013	arterial blood specimen	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen		A specimen that is derived from some arterial blood
http://purl.obolibrary.org/obo/OBI_2000014	venous blood specimen	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen		A specimen that is derived from some venous blood
http://purl.obolibrary.org/obo/OBI_2000015	capillary blood specimen	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen		A specimen that is derived from some capillary blood
http://purl.obolibrary.org/obo/OBI_2000016	erythrocyte specimen	http://purl.obolibrary.org/obo/OBI_0001468	cell specimen		A specimen that is derived from some erythrocytes
http://purl.obolibrary.org/obo/OBI_2000017	reticulocyte specimen	http://purl.obolibrary.org/obo/OBI_0001468	cell specimen		A specimen that is derived from some reticulocytes
http://purl.obolibrary.org/obo/OBI_2000018	leukocyte specimen	http://purl.obolibrary.org/obo/OBI_0001468	cell specimen		A specimen that is derived from some leukocytes
http://purl.obolibrary.org/obo/OBI_0003231	leukapheresis	http://purl.obolibrary.org/obo/OBI_1110095	blood specimen collection		A blood specimen collection in which white blood cells are separated from a blood specimen.
http://purl.obolibrary.org/obo/OBI_0003292	cytometric bead array assay measuring epitope specific granulysin release by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects epitope specific granulysin release by T cells.
http://purl.obolibrary.org/obo/OBI_0003488	cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells	http://purl.obolibrary.org/obo/OBI_0001400	assay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells		A reporter cell line analyte detection bioassay that detects tumor necrosis factor superfamily cytokine production by T cells.
http://purl.obolibrary.org/obo/OBI_0003656	water filtration	http://purl.obolibrary.org/obo/OBI_0302885	filtration		A filtration process of water intended to remove or reduce the concentration of particulate matter, such as suspended particles, parasites, bacteria, algae, viruses, and fungi, as well as other undesirable chemical and biological contaminants.
http://purl.obolibrary.org/obo/OBI_0003725	survey administration assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that obtains data from one or more participants by using a survey or questionnaire
http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter that is compound-dependent and relates to biological interactions or transformations (e.g., clearance, binding, partition coefficients).
http://purl.obolibrary.org/obo/PBPKO_00002	parameter	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item involved in PBPK modelling.
http://purl.obolibrary.org/obo/PBPKO_00146	distribution process	http://purl.obolibrary.org/obo/GO_0008150	biological process		A biological process describing the movement of a compound from systemic circulation to various organs/tissues.
http://purl.obolibrary.org/obo/PBPKO_00322	elimination	http://purl.obolibrary.org/obo/GO_0008150	biological process		A biological process involving the irreversible removal of a compound from the body, encompassing metabolism and excretion.
http://purl.obolibrary.org/obo/PBPKO_00313	endosomal space compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the endosomal space within cells.
http://purl.obolibrary.org/obo/PBPKO_00320	central compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment in a multi-compartment model representing plasma and highly perfused tissues where distribution is rapid.
http://purl.obolibrary.org/obo/PBPKO_00321	peripheral compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment in a multi-compartment model representing tissues where compound distribution is slower compared to the central compartment.
http://purl.obolibrary.org/obo/PBPKO_00402	bladder compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the urinary bladder.
http://purl.obolibrary.org/obo/PBPKO_00404	extrathoracic compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the extrathoracic region (head, neck, upper respiratory tract).
http://purl.obolibrary.org/obo/PBPKO_00405	thoracic compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the thoracic region (chest).
http://purl.obolibrary.org/obo/PBPKO_00450	rest of body compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the lumped remainder of the body not explicitly modeled as separate organs/tissues.
http://purl.obolibrary.org/obo/PBPKO_00451	arterial plasma	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the plasma specifically within the arterial blood.
http://purl.obolibrary.org/obo/PBPKO_00452	venous plasma compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the plasma specifically within the venous blood.
http://purl.obolibrary.org/obo/PBPKO_00453	richly perfused tissue compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing lumped tissues with high blood flow relative to their volume.
http://purl.obolibrary.org/obo/PBPKO_00454	poorly perfused tissue compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing lumped tissues with low blood flow relative to their volume.
http://purl.obolibrary.org/obo/PBPKO_00460	adipose compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing adipose (fat) tissue.
http://purl.obolibrary.org/obo/PBPKO_00464	blood compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the entirety of the blood (including plasma and cells).
http://purl.obolibrary.org/obo/PBPKO_00465	bone marrow compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the bone marrow.
http://purl.obolibrary.org/obo/PBPKO_00466	brain compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the brain.
http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the skin.
http://purl.obolibrary.org/obo/PBPKO_00473	endocrine gland compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing endocrine glands.
http://purl.obolibrary.org/obo/PBPKO_00479	hair compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing hair.
http://purl.obolibrary.org/obo/PBPKO_00480	heart compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the heart.
http://purl.obolibrary.org/obo/PBPKO_00483	mammary gland compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the mammary gland.
http://purl.obolibrary.org/obo/PBPKO_00484	muscle compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing muscle tissue.
http://purl.obolibrary.org/obo/PBPKO_00485	nail compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing nails.
http://purl.obolibrary.org/obo/PBPKO_00486	pancreas compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the pancreas.
http://purl.obolibrary.org/obo/PBPKO_00488	plasma compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing blood plasma.
http://purl.obolibrary.org/obo/PBPKO_00490	reproductive compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing reproductive organs (gonads).
http://purl.obolibrary.org/obo/PBPKO_00492	spleen compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the spleen.
http://purl.obolibrary.org/obo/PBPKO_00495	barrier compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing a physiological barrier limiting compound movement.
http://purl.obolibrary.org/obo/PBPKO_00552	arterial blood compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the arterial blood.
http://purl.obolibrary.org/obo/PBPKO_00553	digestive system compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the digestive system or parts thereof.
http://purl.obolibrary.org/obo/PBPKO_00554	excreta compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing material eliminated from the body (e.g., urine, feces).
http://purl.obolibrary.org/obo/PBPKO_00555	feces compartment	http://purl.obolibrary.org/obo/PBPKO_00554	excreta compartment		An excreta compartment specifically representing feces.
http://purl.obolibrary.org/obo/PBPKO_00556	urine compartment	http://purl.obolibrary.org/obo/PBPKO_00554	excreta compartment		An excreta compartment specifically representing urine.
http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the kidney(s).
http://purl.obolibrary.org/obo/PBPKO_00558	liver compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the liver.
http://purl.obolibrary.org/obo/PBPKO_00559	lung compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the lung(s).
http://purl.obolibrary.org/obo/PBPKO_00561	venous blood compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the venous blood.
http://purl.obolibrary.org/obo/PBPKO_00218	oatp	http://purl.obolibrary.org/obo/PBPKO_00217	transporter		A transporter family (Organic Anion Transporting Polypeptides) involved in transporting organic anions.
http://purl.obolibrary.org/obo/PBPKO_00145	specific intestinal permeability	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the surface area-normalized transcellular permeability of the intestinal wall for a compound.
http://purl.obolibrary.org/obo/PBPKO_00230	fecal clearance rate	http://purl.obolibrary.org/obo/PBPKO_00229	clearance rate		A clearance rate specifically quantifying elimination via feces.
http://purl.obolibrary.org/obo/PBPKO_00231	sweat clearance rate	http://purl.obolibrary.org/obo/PBPKO_00229	clearance rate		A clearance rate specifically quantifying elimination via sweat.
http://purl.obolibrary.org/obo/PBPKO_00232	urinary clearance rate	http://purl.obolibrary.org/obo/PBPKO_00229	clearance rate		A clearance rate specifically quantifying elimination via urine.
http://purl.obolibrary.org/obo/PBPKO_00233	biliary clearance rate	http://purl.obolibrary.org/obo/PBPKO_00229	clearance rate		A clearance rate specifically quantifying elimination via bile.
http://purl.obolibrary.org/obo/PBPKO_00234	hepatic clearance rate	http://purl.obolibrary.org/obo/PBPKO_00229	clearance rate		A clearance rate specifically quantifying elimination via the liver (metabolism and/or biliary excretion).
http://purl.obolibrary.org/obo/PBPKO_00236	fecal elimination rate constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the rate constant for elimination via fecal excretion.
http://purl.obolibrary.org/obo/PBPKO_00237	renal elimination rate constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the rate constant for elimination via renal (urinary) excretion.
http://purl.obolibrary.org/obo/PBPKO_00429	bile salt effect solubilization ratio	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the ratio of molecules solubilized due to bile salt presence.
http://purl.obolibrary.org/obo/PBPKO_00430	mean precipitation time	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the average time for a compound to precipitate under specific conditions (e.g., in the GI tract).
http://purl.obolibrary.org/obo/PBPKO_00433	particle radius	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical/physical parameter representing the radius of particles (e.g., of the administered compound).
http://purl.obolibrary.org/obo/PBPKO_00436	milk plasma ratio	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the ratio of compound concentration in milk to plasma.
http://purl.obolibrary.org/obo/PBPKO_00440	phmilk	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the pH of milk.
http://purl.obolibrary.org/obo/PBPKO_00128	lipophillicity	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter		A physicochemical parameter representing the affinity or tendency of a compound to dissolve in lipids or hydrophobic environments.
http://purl.obolibrary.org/obo/PBPKO_00130	dissolution in two phase system	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter		A physicochemical parameter representing the ratio of a dissolved compound in a two-phase system (often used interchangeably with partition coefficient).
http://purl.obolibrary.org/obo/PBPKO_00132	water solubility	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter		A physicochemical parameter representing the solubility of a compound specifically in water.
http://purl.obolibrary.org/obo/PBPKO_00135	physiological charge	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter		A physicochemical parameter representing the electrical charge of a molecule at physiological pH.
http://purl.obolibrary.org/obo/PBPKO_00137	hydrogen donor count	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter		A physicochemical parameter representing the integer number of hydrogen bond donors in a molecular entity.
http://purl.obolibrary.org/obo/PBPKO_00138	rotatable bond count	http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter		A physicochemical parameter representing the integer count of rotatable bonds in a molecular entity.
http://purl.obolibrary.org/obo/PBPKO_00011	assigned race	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter representing a geographic ancestral origin category assigned to a population group.
http://purl.obolibrary.org/obo/PBPKO_00063	arterial blood flow rate	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment		A blood flow rate parameter representing the rate of blood flow through the arterial compartment.
http://purl.obolibrary.org/obo/PBPKO_00064	venous blood flow rate	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment		A blood flow rate parameter representing the rate of blood flow returning through the venous compartment.
http://purl.obolibrary.org/obo/PBPKO_00121	arterial volume	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment		A volume parameter representing the total volume of the arterial compartment.
http://purl.obolibrary.org/obo/PBPKO_00122	venous volume	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment		A volume parameter representing the total volume of the venous compartment.
http://purl.obolibrary.org/obo/PBPKO_00296	reference human data set	http://purl.obolibrary.org/obo/IAO_0000100	data set		A data set containing the physiological parameters representing a standard human, often defined by specific characteristics like 70 kg body weight.
http://purl.obolibrary.org/obo/PBPKO_00312	plasma space	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the volume occupied by plasma within a tissue or the body.
http://purl.obolibrary.org/obo/PBPKO_00314	interstitial space	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the fluid-filled space between blood vessels and cells.
http://purl.obolibrary.org/obo/PBPKO_00333	fetus lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing the unborn offspring from the postembryonic stage until birth.
http://purl.obolibrary.org/obo/PBPKO_00336	child lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing individuals typically between 3 and 11 years old.
http://purl.obolibrary.org/obo/PBPKO_00337	teenager lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing individuals typically between eleven and fifteen years old.
http://purl.obolibrary.org/obo/PBPKO_00338	adolescent lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing the transitional stage between teenager and adulthood (approx. 15-18 years).
http://purl.obolibrary.org/obo/PBPKO_00339	adult lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing individuals typically from eighteen to thirty years old.
http://purl.obolibrary.org/obo/PBPKO_00340	middle age lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing individuals typically from thirty to forty-five years old.
http://purl.obolibrary.org/obo/PBPKO_00341	old age lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing individuals typically from forty-five to sixty years old (or older, definitions vary).
http://purl.obolibrary.org/obo/PBPKO_00342	pediatric lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing individuals typically below fifteen years of age.
http://purl.obolibrary.org/obo/PBPKO_00343	geriatric lifestage	http://purl.obolibrary.org/obo/PBPKO_00332	lifestage		A lifestage parameter representing older adults, often considered 60/65 years and older.
http://purl.obolibrary.org/obo/PBPKO_00350	brain mass	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the mass of the brain.
http://purl.obolibrary.org/obo/PBPKO_00353	cranial cerebrospinal fluid flow rate	http://purl.obolibrary.org/obo/PBPKO_00636	bodily fluid flow rate parameter		A bodily fluid flow rate parameter representing the flow rate of cerebrospinal fluid (CSF) compartment in the cranial region.
http://purl.obolibrary.org/obo/PBPKO_00372	fetoplacental volume	http://purl.obolibrary.org/obo/PBPKO_00066	volume of compartment		A volume parameter representing the total volume of the placental compartment for fetus.
http://purl.obolibrary.org/obo/PBPKO_00381	fetoplacental blood flow rate	http://purl.obolibrary.org/obo/PBPKO_00012	blood flow rate to compartment		A blood flow rate parameter representing the rate of blood flow between the fetus and the placenta compartment.
http://purl.obolibrary.org/obo/PBPKO_00439	daily milk intake	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the daily volume of milk ingested (e.g., by an infant).
http://purl.obolibrary.org/obo/PBPKO_00521	age in PBPK model	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the period of lifespan (typically in years) for which the model is simulated.
http://purl.obolibrary.org/obo/PBPKO_00240	oral exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure via the mouth.
http://purl.obolibrary.org/obo/PBPKO_00241	dermal exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure via the skin.
http://purl.obolibrary.org/obo/PBPKO_00242	inhalation exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure via inhalation into the lungs.
http://purl.obolibrary.org/obo/PBPKO_00245	intramuscular exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure involving injection into a muscle.
http://purl.obolibrary.org/obo/PBPKO_00246	intraarterial exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure involving administration directly into an artery.
http://purl.obolibrary.org/obo/PBPKO_00247	intrathecal exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure involving administration into the spinal canal.
http://purl.obolibrary.org/obo/PBPKO_00248	subcutaneous exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure involving administration under the skin.
http://purl.obolibrary.org/obo/PBPKO_00249	nasal exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure via the nasal passages.
http://purl.obolibrary.org/obo/PBPKO_00250	transdermal exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure involving absorption through the skin, typically from a patch.
http://purl.obolibrary.org/obo/PBPKO_00251	ocular exposure	http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure		A route of exposure via the eye.
http://purl.obolibrary.org/obo/PBPKO_00005	perfusion limited model	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model that assumes tissue concentration reaches equilibrium rapidly and uptake/elimination is limited by blood flow rate.
http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter that provides the structural framework for a PBPK model and relates to the organism's physiology (e.g., body weight, organ volume, blood flow).
http://purl.obolibrary.org/obo/PBPKO_00636	bodily fluid flow rate parameter	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the rate of fluid flow to a particular compartment.
http://purl.obolibrary.org/obo/PBPKO_00611	fraction of blood flow to a compartment	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing dimensionless fraction of cardiac output delivered to a compartment.
http://purl.obolibrary.org/obo/PBPKO_00252	output parameter	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter representing a result or prediction generated by the PBPK model.
http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the dimensionless fraction computed by dividing the volume of the compartment by the total body weight.
http://purl.obolibrary.org/obo/PBPKO_00126	physicochemical parameter	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter relating to the physical and chemical properties of a compound (e.g., MW, lipophilicity, solubility, pKa).
http://purl.obolibrary.org/obo/PBPKO_00148	protein binding mediated distributiion process	http://purl.obolibrary.org/obo/PBPKO_00146	distribution process		A distribution process (or molecular function) where substances bind to proteins or related compounds.
http://purl.obolibrary.org/obo/PBPKO_00191	phase I metabolism	http://purl.obolibrary.org/obo/GO_0008152	metabolic process		A metabolism process involving the conversion of exogenous substances to more polar metabolites, often via oxidation, reduction, or hydrolysis (e.g., by CYPs).
http://purl.obolibrary.org/obo/PBPKO_00200	phase II	http://purl.obolibrary.org/obo/GO_0008152	metabolic process		A metabolism process involving the conjugation of phase I products (or parent compounds) to hydrophilic moieties to facilitate excretion.
http://purl.obolibrary.org/obo/PBPKO_00209	phase III	http://purl.obolibrary.org/obo/GO_0008152	metabolic process		A metabolism/transport process involving the further processing and excretion of conjugated metabolites (often involving efflux transporters).
http://purl.obolibrary.org/obo/PBPKO_00210	first pass metabolism	http://purl.obolibrary.org/obo/GO_0008152	metabolic process		A metabolism process occurring at a specific location (e.g., liver, gut wall) after administration but before reaching systemic circulation, reducing the concentration of active compound.
http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing Vmax of the enzymatic activity
http://purl.obolibrary.org/obo/PBPKO_00215	gut metabolism	http://purl.obolibrary.org/obo/GO_0008152	metabolic process		A metabolism process specifically occurring within the gut.
http://purl.obolibrary.org/obo/PBPKO_00217	transporter	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity representing protein responsible for the import or export of compounds across cell membranes.
http://purl.obolibrary.org/obo/PBPKO_00223	renal excretion	http://purl.obolibrary.org/obo/GO_0007588	excretion		An excretion process involving the elimination of compounds and metabolites primarily through urine via the kidneys.
http://purl.obolibrary.org/obo/PBPKO_00224	hepatic excretion	http://purl.obolibrary.org/obo/GO_0007588	excretion		An excretion process involving the elimination of compounds and metabolites via the liver (often into bile).
http://purl.obolibrary.org/obo/PBPKO_00225	fecal excretion	http://purl.obolibrary.org/obo/GO_0007588	excretion		An excretion process involving the elimination of compounds and metabolites through feces.
http://purl.obolibrary.org/obo/PBPKO_00226	exhalation	http://purl.obolibrary.org/obo/GO_0007588	excretion		An excretion process involving the elimination of volatile compounds and metabolites through respiration.
http://purl.obolibrary.org/obo/PBPKO_00227	sweat excretion	http://purl.obolibrary.org/obo/GO_0007588	excretion		An excretion process involving the elimination of compounds and metabolites through sweat.
http://purl.obolibrary.org/obo/PBPKO_00228	hair excretion	http://purl.obolibrary.org/obo/GO_0007588	excretion		An excretion process involving the elimination and deposition of compounds and metabolites into hair.
http://purl.obolibrary.org/obo/PBPKO_00238	biliary elimination	http://purl.obolibrary.org/obo/PBPKO_00322	elimination		An elimination process involving the irreversible transfer of compound or metabolites from plasma to bile via hepatocytes.
http://purl.obolibrary.org/obo/PBPKO_00239	route of exposure	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter designating the body part or method through which exposure is introduced.
http://purl.obolibrary.org/obo/PBPKO_00269	elimination phase	http://purl.obolibrary.org/obo/PBPKO_00322	elimination		An elimination process phase describing the period where removal of the compound from the body predominates.
http://purl.obolibrary.org/obo/PBPKO_00270	absorption phase	http://purl.obolibrary.org/obo/PBPKO_00140	absorption		An absorption process phase describing the period where the compound moves from the administration site into systemic circulation.
http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the amount of chemical specifically in the compartment
http://purl.obolibrary.org/obo/PBPKO_00274	cumulative amount in urine	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the total amount of compound excreted in urine over a specific time period.
http://purl.obolibrary.org/obo/PBPKO_00275	cumulative amount in feces	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the total amount of compound excreted in feces over a specific time period.
http://purl.obolibrary.org/obo/PBPKO_00279	min organ concentration	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the minimum concentration of a compound in a specific organ after exposure.
http://purl.obolibrary.org/obo/PBPKO_00280	max organ concentration	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the maximum concentration of a compound in a specific organ after exposure.
http://purl.obolibrary.org/obo/PBPKO_00281	median organ concentration	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the median concentration of a compound in a specific organ after exposure.
http://purl.obolibrary.org/obo/PBPKO_00282	percentile 2.5 cplasma	http://purl.obolibrary.org/obo/PBPKO_00549	concentration in plasma		A plasma concentration parameter representing the 2.5th percentile of the plasma concentration distribution in a population simulation.
http://purl.obolibrary.org/obo/PBPKO_00283	percentile 97.5 cplasma	http://purl.obolibrary.org/obo/PBPKO_00549	concentration in plasma		A plasma concentration parameter representing the 97.5th percentile of the plasma concentration distribution in a population simulation.
http://purl.obolibrary.org/obo/PBPKO_00285	reconstructed exposure	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter estimating the amount of compound exposure based on internal body measurements.
http://purl.obolibrary.org/obo/PBPKO_00297	biological matrix concentration	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the total concentration of a compound in a specified biological matrix.
http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	http://purl.obolibrary.org/obo/PBPKO_00252	output parameter		An output parameter representing the total concentration of compound in the compartment.
http://purl.obolibrary.org/obo/PBPKO_00303	permeability limited pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model that considers the permeability across membranes as a limiting factor for compound distribution.
http://purl.obolibrary.org/obo/PBPKO_00446	compartment	http://purl.obolibrary.org/obo/OBI_0000658	data representational model		A data representation model component representing a distinct physiological space (organ, tissue, fluid) where ADME processes occur.
http://purl.obolibrary.org/obo/PBPKO_00316	population pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model approach used to characterize interindividual variability within a population.
http://purl.obolibrary.org/obo/PBPKO_00332	lifestage	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing distinct phases of an individual's life (e.g., infant, adult, geriatric).
http://purl.obolibrary.org/obo/PBPKO_00317	top-down pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model approach primarily based on fitting observed clinical data, often empirical.
http://purl.obolibrary.org/obo/PBPKO_00318	bottom-up pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model approach built mechanistically using in vitro and physiological data.
http://purl.obolibrary.org/obo/PBPKO_00319	one-compartment pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model that treats the entire body as a single, kinetically homogenous unit (central compartment).
http://purl.obolibrary.org/obo/PBPKO_00323	linear elimination	http://purl.obolibrary.org/obo/PBPKO_00322	elimination		An elimination process that follows first-order kinetics (rate proportional to concentration).
http://purl.obolibrary.org/obo/PBPKO_00324	non-linear elimination	http://purl.obolibrary.org/obo/PBPKO_00322	elimination		An elimination process that does not follow first-order kinetics (e.g., saturable processes).
http://purl.obolibrary.org/obo/PBPKO_00347	brain pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model specifically built to predict compound concentrations in the brain.
http://purl.obolibrary.org/obo/PBPKO_00612	apparent permeability	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the apparent permeability of a compound specifically between the compartments.
http://purl.obolibrary.org/obo/PBPKO_00371	pregnant pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model specifically built to predict compound concentrations during pregnancy.
http://purl.obolibrary.org/obo/PBPKO_00395	kidney pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model specifically built to predict compound concentrations within the kidney compartments.
http://purl.obolibrary.org/obo/PBPKO_00396	Bowman's capsule compartment	http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment		A kidney compartment representing the Bowman's capsule.
http://purl.obolibrary.org/obo/PBPKO_00397	filtrate compartment	http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment		A kidney compartment representing the filtrate within the nephron.
http://purl.obolibrary.org/obo/PBPKO_00398	proximal tubule compartment	http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment		A kidney compartment representing the proximal tubule of the nephron.
http://purl.obolibrary.org/obo/PBPKO_00399	loop of Henle compartment	http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment		A kidney compartment representing the loop of Henle within the nephron.
http://purl.obolibrary.org/obo/PBPKO_00400	distal tubule compartment	http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment		A kidney compartment representing the distal tubule of the nephron.
http://purl.obolibrary.org/obo/PBPKO_00401	collecting duct compartment	http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment		A kidney compartment representing the collecting duct system.
http://purl.obolibrary.org/obo/PBPKO_00403	lung pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model specifically built to predict compound concentrations within the lung compartments.
http://purl.obolibrary.org/obo/PBPKO_00406	bronchiolar compartment	http://purl.obolibrary.org/obo/PBPKO_00559	lung compartment		A lung compartment representing the bronchioles.
http://purl.obolibrary.org/obo/PBPKO_00407	alveolar compartment	http://purl.obolibrary.org/obo/PBPKO_00559	lung compartment		A lung compartment representing the alveoli.
http://purl.obolibrary.org/obo/PBPKO_00408	gut pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model specifically built to predict compound concentrations within the gut compartments.
http://purl.obolibrary.org/obo/NCBITaxon_2559587	Riboviria	http://purl.obolibrary.org/obo/NCBITaxon_10239	Viruses	RNA viruses and viroids	
http://purl.obolibrary.org/obo/NCBITaxon_10407	Hepatitis B virus	http://purl.obolibrary.org/obo/NCBITaxon_2732514	Revtraviricetes	human hepatitis B virus HBV	
http://purl.obolibrary.org/obo/NCBITaxon_11676	Human immunodeficiency virus 1	http://purl.obolibrary.org/obo/NCBITaxon_11646	Lentivirus	human immunodeficiency virus-1 HIV-1	
http://purl.obolibrary.org/obo/NCBITaxon_11709	Human immunodeficiency virus 2	http://purl.obolibrary.org/obo/NCBITaxon_11646	Lentivirus	human immunodeficiency virus type 2, HIV-2	
http://purl.obolibrary.org/obo/BFO_0000148	zero-dimensional temporal region	http://purl.obolibrary.org/obo/BFO_0000008	temporal region	temporal instant.	
http://purl.obolibrary.org/obo/NCBITaxon_3702	Arabidopsis thaliana	http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota	thale-cress	
http://purl.obolibrary.org/obo/NCBITaxon_4896	Schizosaccharomyces pombe	http://purl.obolibrary.org/obo/NCBITaxon_4890	Ascomycota	fission yeast	
http://purl.obolibrary.org/obo/NCBITaxon_4932	Saccharomyces cerevisiae	http://purl.obolibrary.org/obo/NCBITaxon_716545	saccharomyceta	Saccharomyces cerevisiae 'var. diastaticus'	
http://purl.obolibrary.org/obo/NCBITaxon_6668	Daphnia	http://purl.obolibrary.org/obo/NCBITaxon_197562	Pancrustacea	common water fleas	
http://purl.obolibrary.org/obo/NCBITaxon_7227	Drosophila melanogaster	http://purl.obolibrary.org/obo/NCBITaxon_7147	Diptera	fruit fly	
http://purl.obolibrary.org/obo/NCBITaxon_8353	Xenopus <genus>	http://purl.obolibrary.org/obo/NCBITaxon_32523	Tetrapoda	Xenopus	
http://purl.obolibrary.org/obo/NCBITaxon_9606	Homo sapiens	http://purl.obolibrary.org/obo/NCBITaxon_314146	Euarchontoglires	human being	
http://purl.obolibrary.org/obo/NCBITaxon_10090	Mus musculus	http://purl.obolibrary.org/obo/NCBITaxon_39107	Murinae	house mouse	
http://purl.obolibrary.org/obo/NCBITaxon_10116	Rattus norvegicus	http://purl.obolibrary.org/obo/NCBITaxon_39107	Murinae	rats	
http://purl.obolibrary.org/obo/NCBITaxon_10376	human gammaherpesvirus 4	http://purl.obolibrary.org/obo/NCBITaxon_3044472	Orthoherpesviridae	Human herpesvirus 4 (Epstein-Barr virus)	
http://purl.obolibrary.org/obo/NCBITaxon_2	Bacteria	http://purl.obolibrary.org/obo/OBI_0100026	organism	eubacteria	
http://purl.obolibrary.org/obo/NCBITaxon_4890	Ascomycota	http://purl.obolibrary.org/obo/NCBITaxon_33154	Opisthokonta	sac fungi	
http://purl.obolibrary.org/obo/NCBITaxon_11050	Flaviviridae	http://purl.obolibrary.org/obo/NCBITaxon_2732406	Kitrinoviricota	Flavivirus (arbovirus group B)	
http://purl.obolibrary.org/obo/NCBITaxon_11646	Lentivirus	http://purl.obolibrary.org/obo/NCBITaxon_2732514	Revtraviricetes	Lentivirinae	
http://purl.obolibrary.org/obo/NCBITaxon_117571	Euteleostomi	http://purl.obolibrary.org/obo/NCBITaxon_7742	Vertebrata <vertebrates>	bony vertebrates	
http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota	http://purl.obolibrary.org/obo/OBI_0100026	organism	eukaryotes	
http://purl.obolibrary.org/obo/NCBITaxon_32523	Tetrapoda	http://purl.obolibrary.org/obo/NCBITaxon_117571	Euteleostomi	tetrapods	
http://purl.obolibrary.org/obo/NCBITaxon_32524	Amniota	http://purl.obolibrary.org/obo/NCBITaxon_32523	Tetrapoda	amniotes	
http://purl.obolibrary.org/obo/NCBITaxon_33208	Metazoa	http://purl.obolibrary.org/obo/NCBITaxon_33154	Opisthokonta	multicellular animals	
http://purl.obolibrary.org/obo/NCBITaxon_40674	Mammalia	http://purl.obolibrary.org/obo/NCBITaxon_32524	Amniota	mammals	
http://purl.obolibrary.org/obo/NCBITaxon_6656	Arthropoda	http://purl.obolibrary.org/obo/NCBITaxon_1206794	Ecdysozoa	arthropods	
http://purl.obolibrary.org/obo/NCBITaxon_7147	Diptera	http://purl.obolibrary.org/obo/NCBITaxon_197562	Pancrustacea	flies	
http://purl.obolibrary.org/obo/NCBITaxon_7157	Culicidae	http://purl.obolibrary.org/obo/NCBITaxon_7147	Diptera	mosquitos	
http://purl.obolibrary.org/obo/NCBITaxon_7742	Vertebrata <vertebrates>	http://purl.obolibrary.org/obo/NCBITaxon_33213	Bilateria	vertebrates	
http://purl.obolibrary.org/obo/NCBITaxon_7955	Danio rerio	http://purl.obolibrary.org/obo/NCBITaxon_117571	Euteleostomi	zebrafish	
http://purl.obolibrary.org/obo/NCBITaxon_9031	Gallus gallus	http://purl.obolibrary.org/obo/NCBITaxon_32524	Amniota	chickens	
http://purl.obolibrary.org/obo/NCBITaxon_9989	Rodentia	http://purl.obolibrary.org/obo/NCBITaxon_314146	Euarchontoglires	rodent	
http://purl.obolibrary.org/obo/NCBITaxon_3052230	Hepacivirus hominis	http://purl.obolibrary.org/obo/NCBITaxon_11050	Flaviviridae	human hepatitis virus C HCV	
http://purl.obolibrary.org/obo/CHEBI_23528	cytochalasin	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_24875	iron cation	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_29191	hydroxyl	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_39124	calcium ion	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_81568	Luteinizing hormone	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_81569	Follicle stimulating hormone	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_17137	hydrogensulfite	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_30682	ruthenium atom	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_33262	elemental oxygen	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_33375	gadolinium atom	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_33376	terbium atom	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_27889	lead(0)	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_35729	gadolinium molecular entity	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_37586	sodium phosphate	http://purl.obolibrary.org/obo/CHEBI_23367	molecular entity		
http://purl.obolibrary.org/obo/CHEBI_33321	rare earth metal atom	http://purl.obolibrary.org/obo/CHEBI_33250	atom		
http://purl.obolibrary.org/obo/CHEBI_39123	calcium cation	http://purl.obolibrary.org/obo/CHEBI_39124	calcium ion		
http://purl.obolibrary.org/obo/UPHENO_0001001	phenotype	http://purl.obolibrary.org/obo/PATO_0000001	quality		
http://purl.obolibrary.org/obo/OBI_0003649	liquid chromatography-tandem mass spectrometry analysis	http://purl.obolibrary.org/obo/OBI_0003648	liquid chromatrography mass spectrometry analysis		
http://purl.obolibrary.org/obo/NCBITaxon_3044472	Orthoherpesviridae	http://purl.obolibrary.org/obo/NCBITaxon_10239	Viruses		
http://purl.obolibrary.org/obo/NCBITaxon_388799	HIV-1 group O	http://purl.obolibrary.org/obo/NCBITaxon_11676	Human immunodeficiency virus 1		
http://purl.obolibrary.org/obo/BFO_0000008	temporal region	http://purl.obolibrary.org/obo/BFO_0000003	occurrent		
http://purl.obolibrary.org/obo/BFO_0000011	spatiotemporal region	http://purl.obolibrary.org/obo/BFO_0000003	occurrent		
http://purl.obolibrary.org/obo/BFO_0000141	immaterial entity	http://purl.obolibrary.org/obo/BFO_0000004	independent continuant		
http://purl.obolibrary.org/obo/BFO_0000009	two-dimensional spatial region	http://purl.obolibrary.org/obo/BFO_0000006	spatial region		
http://purl.obolibrary.org/obo/BFO_0000018	zero-dimensional spatial region	http://purl.obolibrary.org/obo/BFO_0000006	spatial region		
http://purl.obolibrary.org/obo/BFO_0000026	one-dimensional spatial region	http://purl.obolibrary.org/obo/BFO_0000006	spatial region		
http://purl.obolibrary.org/obo/BFO_0000028	three-dimensional spatial region	http://purl.obolibrary.org/obo/BFO_0000006	spatial region		
http://purl.obolibrary.org/obo/BFO_0000038	one-dimensional temporal region	http://purl.obolibrary.org/obo/BFO_0000008	temporal region		
http://purl.obolibrary.org/obo/BFO_0000182	history	http://purl.obolibrary.org/obo/BFO_0000015	process		
http://purl.obolibrary.org/obo/BFO_0000034	function	http://purl.obolibrary.org/obo/BFO_0000016	disposition		
http://purl.obolibrary.org/obo/BFO_0000016	disposition	http://purl.obolibrary.org/obo/BFO_0000017	realizable entity		
http://purl.obolibrary.org/obo/OBA_0000001	biological attribute	http://purl.obolibrary.org/obo/BFO_0000019	quality		
http://purl.obolibrary.org/obo/BFO_0000019	quality	http://purl.obolibrary.org/obo/BFO_0000020	specifically dependent continuant		
http://purl.obolibrary.org/obo/BFO_0000024	fiat object	http://purl.obolibrary.org/obo/BFO_0000040	material entity		
http://purl.obolibrary.org/obo/BFO_0000027	object aggregate	http://purl.obolibrary.org/obo/BFO_0000040	material entity		
http://purl.obolibrary.org/obo/BFO_0000030	object	http://purl.obolibrary.org/obo/BFO_0000040	material entity		
http://purl.obolibrary.org/obo/BFO_0000142	one-dimensional continuant fiat boundary	http://purl.obolibrary.org/obo/BFO_0000140	continuant fiat boundary		
http://purl.obolibrary.org/obo/BFO_0000146	two-dimensional continuant fiat boundary	http://purl.obolibrary.org/obo/BFO_0000140	continuant fiat boundary		
http://purl.obolibrary.org/obo/BFO_0000147	zero-dimensional continuant fiat boundary	http://purl.obolibrary.org/obo/BFO_0000140	continuant fiat boundary		
http://purl.obolibrary.org/obo/BFO_0000006	spatial region	http://purl.obolibrary.org/obo/BFO_0000141	immaterial entity		
http://purl.obolibrary.org/obo/BFO_0000029	site	http://purl.obolibrary.org/obo/BFO_0000141	immaterial entity		
http://purl.obolibrary.org/obo/UO_0000001	length unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000002	mass unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000003	time unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000005	temperature unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000006	substance unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000051	concentration unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000095	volume unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000105	frequency unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000109	pressure unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000270	volumetric flow rate unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/UO_0000280	rate unit	http://purl.obolibrary.org/obo/IAO_0000003	measurement unit label		
http://purl.obolibrary.org/obo/IAO_0000429	email address	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		
http://purl.obolibrary.org/obo/NCBITaxon_10239	Viruses	http://purl.obolibrary.org/obo/OBI_0100026	organism		
http://purl.obolibrary.org/obo/NCBITaxon_2157	Archaea	http://purl.obolibrary.org/obo/OBI_0100026	organism		
http://purl.obolibrary.org/obo/OBI_0003647	tandem mass spectrometry analysis	http://purl.obolibrary.org/obo/OBI_0200085	mass spectrometry analysis		
http://purl.obolibrary.org/obo/OBI_0003648	liquid chromatrography mass spectrometry analysis	http://purl.obolibrary.org/obo/OBI_0200085	mass spectrometry analysis		
http://purl.obolibrary.org/obo/PR_000029983	protein-glutamine gamma-glutamyltransferase	http://purl.obolibrary.org/obo/PR_000000001	protein		
http://purl.obolibrary.org/obo/OBI_0000340	obsolete_documenting	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/OBI_0000794	obsolete transcription factor binding site	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/OBI_0000851	obsolete_diethyl pyrocarbonate	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/OBI_0000926	obsolete_ambidexterious handedness	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/OBI_0000937	obsolete_left handedness	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/OBI_0000956	obsolete_handedness	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/OBI_0000974	obsolete_right handedness	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/OBI_0000987	obsolete_general scalar measurement datum	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		
http://purl.obolibrary.org/obo/CHEBI_4705	double-stranded DNA	http://purl.obolibrary.org/obo/CHEBI_16991	deoxyribonucleic acid		
http://purl.obolibrary.org/obo/CHEBI_28774	3,3',5'-triiodothyronine	http://purl.obolibrary.org/obo/CHEBI_33709	amino acid		
http://purl.obolibrary.org/obo/NCBITaxon_784	Orientia tsutsugamushi	http://purl.obolibrary.org/obo/NCBITaxon_2	Bacteria		
http://purl.obolibrary.org/obo/NCBITaxon_160	Treponema pallidum	http://purl.obolibrary.org/obo/NCBITaxon_2	Bacteria		
http://purl.obolibrary.org/obo/NCBITaxon_716545	saccharomyceta	http://purl.obolibrary.org/obo/NCBITaxon_4890	Ascomycota		
http://purl.obolibrary.org/obo/CHEBI_81567	thyroid stimulating hormone	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		
http://purl.obolibrary.org/obo/CHEBI_35143	hemoglobin	http://purl.obolibrary.org/obo/CHEBI_33839	macromolecule		
http://purl.obolibrary.org/obo/NCBITaxon_12637	Dengue virus	http://purl.obolibrary.org/obo/NCBITaxon_11050	Flaviviridae		
http://purl.obolibrary.org/obo/NCBITaxon_6239	Caenorhabditis elegans	http://purl.obolibrary.org/obo/NCBITaxon_1206794	Ecdysozoa		
http://purl.obolibrary.org/obo/NCBITaxon_44689	Dictyostelium discoideum	http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota		
http://purl.obolibrary.org/obo/NCBITaxon_5820	Plasmodium	http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota		
http://purl.obolibrary.org/obo/NCBITaxon_33154	Opisthokonta	http://purl.obolibrary.org/obo/NCBITaxon_2759	Eukaryota		
http://purl.obolibrary.org/obo/NCBITaxon_33213	Bilateria	http://purl.obolibrary.org/obo/NCBITaxon_33208	Metazoa		
http://purl.obolibrary.org/obo/NCBITaxon_1206794	Ecdysozoa	http://purl.obolibrary.org/obo/NCBITaxon_33213	Bilateria		
http://purl.obolibrary.org/obo/NCBITaxon_314146	Euarchontoglires	http://purl.obolibrary.org/obo/NCBITaxon_40674	Mammalia		
http://purl.obolibrary.org/obo/NCBITaxon_197562	Pancrustacea	http://purl.obolibrary.org/obo/NCBITaxon_6656	Arthropoda		
http://purl.obolibrary.org/obo/NCBITaxon_5140	Neurospora	http://purl.obolibrary.org/obo/NCBITaxon_716545	saccharomyceta		
http://purl.obolibrary.org/obo/NCBITaxon_39107	Murinae	http://purl.obolibrary.org/obo/NCBITaxon_9989	Rodentia		
http://purl.obolibrary.org/obo/UBERON_0006911	digestive system secreted substance	http://purl.obolibrary.org/obo/UBERON_0000463	organism substance		
http://purl.obolibrary.org/obo/NCBITaxon_10358	Cytomegalovirus	http://purl.obolibrary.org/obo/NCBITaxon_3044472	Orthoherpesviridae		
http://biomodels.net/SBO/SBO_0000027	Michaelis constant	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		
http://purl.obolibrary.org/obo/CHEBI_37987	Cy3 dye	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		
http://purl.obolibrary.org/obo/CHEBI_37989	Cy5 dye	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		
http://purl.obolibrary.org/obo/CHEBI_51756	Alexa Fluor 532	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		
http://purl.obolibrary.org/obo/CHEBI_51760	Alexa Fluor 546	http://purl.obolibrary.org/obo/OBI_0002744	molecular label		
http://purl.obolibrary.org/obo/NCBITaxon_37124	Chikungunya virus	http://purl.obolibrary.org/obo/NCBITaxon_2732406	Kitrinoviricota		
http://purl.obolibrary.org/obo/PBPKO_00438	concentration in milk	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cmilk	The total concentration of compound in the milk compartment.
http://purl.obolibrary.org/obo/PBPKO_00441	blood milk barrier compartment	http://purl.obolibrary.org/obo/PBPKO_00495	barrier compartment	bmb compartment	A barrier compartment representing the physiological barrier separating blood and milk in lactating species.
http://purl.obolibrary.org/obo/PBPKO_00496	amount in gut	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	agut	The amount of compound in the gut compartment.
http://purl.obolibrary.org/obo/PBPKO_00497	amount in liver	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	aliver	The amount of compound in the liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00498	amount in kidney	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	akidney	The amount of compound in the kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00499	amount in filtrate	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	afiltrate	The amount of compound in the filtrate compartment.
http://purl.obolibrary.org/obo/PBPKO_00500	amount in delay	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	adelay	The amount of compound in the hypothetical delay compartment.
http://purl.obolibrary.org/obo/PBPKO_00501	amount in restbody	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	arestbody	The amount of compound in the rest of the body compartment.
http://purl.obolibrary.org/obo/PBPKO_00502	amount in plasma	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	aplasma	The amount of compound in the plasma compartment.
http://purl.obolibrary.org/obo/PBPKO_00503	amount in brain	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	abrain	The amount of compound in the brain compartment.
http://purl.obolibrary.org/obo/PBPKO_00504	amount in lung	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	alung	The amount of compound in the lung compartment.
http://purl.obolibrary.org/obo/PBPKO_00505	amount in bone marrow	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	abm	The amount of compound in the bone marrow compartment.
http://purl.obolibrary.org/obo/PBPKO_00506	amount in skin	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	askin	The amount of compound in the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00507	amount in mammary gland	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	amam	The amount of compound in the mammary gland compartment.
http://purl.obolibrary.org/obo/PBPKO_00538	concentration in gut	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cgut	The total concentration of compound in the gut compartment.
http://purl.obolibrary.org/obo/PBPKO_00539	concentration in liver	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cliver	The total concentration of compound in the liver compartment.
http://purl.obolibrary.org/obo/PBPKO_00540	concentration in brain	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cbrain	The total concentration of compound in the brain compartment.
http://purl.obolibrary.org/obo/PBPKO_00541	concentration in kidney	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	ckidney	The total concentration of compound in the kidney compartment.
http://purl.obolibrary.org/obo/PBPKO_00542	concentration in filtrate	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cfiltrate	The total concentration of compound in the filtrate compartment.
http://purl.obolibrary.org/obo/PBPKO_00543	concentration in lung	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	clung	The total concentration of compound in the lung compartment.
http://purl.obolibrary.org/obo/PBPKO_00544	concentration in fat	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cfat	The total concentration of compound in the fat compartment.
http://purl.obolibrary.org/obo/PBPKO_00545	concentration in bone marrow	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cbm	The total concentration of compound in the bone marrow compartment.
http://purl.obolibrary.org/obo/PBPKO_00546	concentration in skin	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cksin	The total concentration of compound in the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00547	concentration in mammary gland	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	cmam	The total concentration of compound in the mammary gland compartment.
http://purl.obolibrary.org/obo/PBPKO_00548	concentration in restbody	http://purl.obolibrary.org/obo/PBPKO_00616	concentration of compound in compartment	crestbody	The total concentration of compound in the rest of body compartment.
http://purl.obolibrary.org/obo/PBPKO_00550	amount in fat	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	afat	The amount of compound in the fat compartment.
http://purl.obolibrary.org/obo/PBPKO_00562	blood flow rate to unexposed skin	http://purl.obolibrary.org/obo/PBPKO_00036	blood flow rate to skin	qskinu	A blood flow rate to skin parameter specifically describing the rate to the unexposed portion of the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00563	blood flow rate to exposed skin	http://purl.obolibrary.org/obo/PBPKO_00036	blood flow rate to skin	qskine	A blood flow rate to skin parameter specifically describing the rate to the exposed portion of the skin compartment.
http://purl.obolibrary.org/obo/PBPKO_00564	blood flow rate to skin stratum corneum unexposed	http://purl.obolibrary.org/obo/PBPKO_00036	blood flow rate to skin	qskinscu	A blood flow rate to skin parameter specifically describing the rate to the unexposed stratum corneum compartment.
http://purl.obolibrary.org/obo/PBPKO_00565	blood flow rate to skin stratum corneum exposed	http://purl.obolibrary.org/obo/PBPKO_00036	blood flow rate to skin	qskinsce	A blood flow rate to skin parameter specifically describing the rate to the exposed stratum corneum compartment.
http://purl.obolibrary.org/obo/PBPKO_00567	bone blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	bone blood pc	A partition coefficient representing the ratio of compound concentration in bone to blood.
http://purl.obolibrary.org/obo/PBPKO_00568	air blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	air blood pc	A partition coefficient representing the ratio of compound concentration in air to blood.
http://purl.obolibrary.org/obo/PBPKO_00569	brain blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	brain blood pc	A partition coefficient representing the ratio of compound concentration in brain to blood.
http://purl.obolibrary.org/obo/PBPKO_00570	brainfetus blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	brainfetus blood pc	A partition coefficient representing the ratio of compound concentration in the fetal brain to blood.
http://purl.obolibrary.org/obo/PBPKO_00571	gonad blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	gonad blood pc	A partition coefficient representing the ratio of compound concentration in gonads to blood.
http://purl.obolibrary.org/obo/PBPKO_00572	gut blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	gut blood pc	A partition coefficient representing the ratio of compound concentration in the gut to blood.
http://purl.obolibrary.org/obo/PBPKO_00573	heart blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	heart blood pc	A partition coefficient representing the ratio of compound concentration in the heart to blood.
http://purl.obolibrary.org/obo/PBPKO_00574	intestine blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	intestine blood pc	A partition coefficient representing the ratio of compound concentration in the intestine to blood.
http://purl.obolibrary.org/obo/PBPKO_00575	kidney blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	kidney blood pc	A partition coefficient representing the ratio of compound concentration in the kidney to blood.
http://purl.obolibrary.org/obo/PBPKO_00576	kidneyfetus blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	kidneyfetus blood pc	A partition coefficient representing the ratio of compound concentration in the fetal kidney to blood.
http://purl.obolibrary.org/obo/PBPKO_00577	liver blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	liver blood pc	A partition coefficient representing the ratio of compound concentration in the liver to blood.
http://purl.obolibrary.org/obo/PBPKO_00578	liverfetus blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	liverfetus blood pc	A partition coefficient representing the ratio of compound concentration in the fetal liver to blood.
http://purl.obolibrary.org/obo/PBPKO_00579	lung blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	lung blood pc	A partition coefficient representing the ratio of compound concentration in the lung to blood.
http://purl.obolibrary.org/obo/PBPKO_00580	mammary gland blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	mam blood pc	A partition coefficient representing the ratio of compound concentration in the mammary gland to blood.
http://purl.obolibrary.org/obo/PBPKO_00581	milk blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	milk blood pc	A partition coefficient representing the ratio of compound concentration in milk to blood.
http://purl.obolibrary.org/obo/PBPKO_00582	muscle blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	muscle blood pc	A partition coefficient representing the ratio of compound concentration in muscle to blood.
http://purl.obolibrary.org/obo/PBPKO_00583	pancreas blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	pancreas blood pc	A partition coefficient representing the ratio of compound concentration in the pancreas to blood.
http://purl.obolibrary.org/obo/PBPKO_00584	poor perfused blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	poor perfused blood pc	A partition coefficient representing the ratio of compound concentration in the poorly perfused compartment to blood.
http://purl.obolibrary.org/obo/PBPKO_00585	restbody blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	restbody blood pc	A partition coefficient representing the ratio of compound concentration in the rest of body compartment to blood.
http://purl.obolibrary.org/obo/PBPKO_00586	restbodyfetus blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	restbodyfetus blood pc	A partition coefficient representing the ratio of compound concentration in the fetal rest of body compartment to blood.
http://purl.obolibrary.org/obo/PBPKO_00587	rich perfused blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	rich perfused blood pc	A partition coefficient representing the ratio of compound concentration in the richly perfused compartment to blood.
http://purl.obolibrary.org/obo/PBPKO_00588	skin blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	skin blood pc	A partition coefficient representing the ratio of compound concentration in the skin to blood.
http://purl.obolibrary.org/obo/PBPKO_00589	spleen blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	spleen blood pc	A partition coefficient representing the ratio of compound concentration in the spleen to blood.
http://purl.obolibrary.org/obo/PBPKO_00590	stomach blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	stomach blood pc	A partition coefficient representing the ratio of compound concentration in the stomach to blood.
http://purl.obolibrary.org/obo/PBPKO_00591	fraction unbound plasma	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fuplasma	An unbound fraction parameter specifically for plasma.
http://purl.obolibrary.org/obo/PBPKO_00592	maximum rate of apical transporter	http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	Vmax apical	A maximum rate (Vmax) of an enzyme catalysed reaction for a compound across the apical membrane of an organ when the enzyme is saturated with substrate.
http://purl.obolibrary.org/obo/PBPKO_00593	maximum rate of basolateral transporter	http://purl.obolibrary.org/obo/PBPKO_00613	maximum rate	vmax baso	Maximum rate (Vmax) of transport via a basolateral transporter.
http://purl.obolibrary.org/obo/PBPKO_00622	fraction unbound blood	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	fublood	An unbound fraction parameter specifically for the blood compartment.
http://purl.obolibrary.org/obo/PBPKO_00623	amount in blood	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	ablood	The amount of compound in the blood compartment.
http://purl.obolibrary.org/obo/PBPKO_00624	fraction unbound restbody	http://purl.obolibrary.org/obo/PBPKO_00149	unbound fraction	furestbody	An unbound fraction parameter specifically for the rest of the body compartment.
http://purl.obolibrary.org/obo/PBPKO_00627	fraction of arterial plasma volume	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	farterialplasma	A dimensionless fraction of volume defined as the arterial plasma volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00628	fraction of venous plasma volume	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	fvenousplasma	A dimensionless fraction of volume defined as the venous plasma volume divided per unit of total body weight.
http://purl.obolibrary.org/obo/PBPKO_00629	amount in richly perfused tissue	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	arichlyperfused	The amount of compound in the richly perfused tissue compartment.
http://purl.obolibrary.org/obo/PBPKO_00630	amount in poorly perfused tissue	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	apoorlyperfused	The amount of compound in the poorly perfused tissue compartment.
http://purl.obolibrary.org/obo/PBPKO_00631	amount in arterial blood	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	aarterialblood	The amount of compound in the arterial blood compartment.
http://purl.obolibrary.org/obo/PBPKO_00632	amount in venous blood	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	avenousblood	The amount of compound in the venous blood compartment.
http://purl.obolibrary.org/obo/PBPKO_00633	amount in alveolar air	http://purl.obolibrary.org/obo/PBPKO_00615	amount of compound in compartment	aalveolar	The amount of compound in the alveolar air compartment.
http://purl.obolibrary.org/obo/PBPKO_00637	amount in viable epidermis of unexposed skin	http://purl.obolibrary.org/obo/PBPKO_00506	amount in skin	askin_u	The amount of chemical in viable epidermis of unexposed skin
http://purl.obolibrary.org/obo/PBPKO_00638	amount in viable epidermis of exposed skin	http://purl.obolibrary.org/obo/PBPKO_00506	amount in skin	askin_e	The amount of chemical in viable epidermis of exposed skin
http://purl.obolibrary.org/obo/PBPKO_00639	amount in skin stratum corneum of unexposed skin	http://purl.obolibrary.org/obo/PBPKO_00506	amount in skin	askin_sc_u	The amount of chemical in skin stratum corneum of unexposed skin
http://purl.obolibrary.org/obo/PBPKO_00640	amount in skin stratum corneum of exposed skin	http://purl.obolibrary.org/obo/PBPKO_00506	amount in skin	askin_sc_e	The amount of chemical in skin stratum corneum of exposed skin
http://purl.obolibrary.org/obo/PBPKO_00641	dermal absorption rate unexposed skin	https://github.com/Crispae/pbpko/blob/main/pbpko.owl#OWLClass_6a86eddf_f1dc_4deb_90e9_3d52926078cd	absorption rate constant	fs_u	An absorption rate constant parameter representing dermal absorption rate flux through unexposed skin
http://purl.obolibrary.org/obo/PBPKO_00642	dermal absorption rate exposed skin 	https://github.com/Crispae/pbpko/blob/main/pbpko.owl#OWLClass_6a86eddf_f1dc_4deb_90e9_3d52926078cd	absorption rate constant	fs_e	An absorption rate constant parameter representing dermal absorption rate flux through exposed skin 
http://purl.obolibrary.org/obo/PBPKO_00643	thickness stratum corneum	http://purl.obolibrary.org/obo/PBPKO_00635	skin thickness	height_sc	A skin thickness parameter representing the thickness of stratum corneum.
http://purl.obolibrary.org/obo/PBPKO_00644	thickness viable epidermis	http://purl.obolibrary.org/obo/PBPKO_00635	skin thickness	height_vs	A skin thickness parameter representing the thickness of viable epidermis.
http://purl.obolibrary.org/obo/PBPKO_00645	fat blood partition coefficient	http://purl.obolibrary.org/obo/PBPKO_00165	partition coefficient	fat blood pc
PCFat	A partition coefficient representing the ratio of compound concentration in fat to blood.
http://purl.obolibrary.org/obo/PBPKO_00648	diffusion rate stratum corneum viable epidermis 	http://purl.obolibrary.org/obo/PBPKO_00647	diffusion rate skin	kp_sc_vs	A diffusion rate skin parameter representing diffusion rate from stratum corneum to viable epidermis
http://purl.obolibrary.org/obo/PBPKO_00651	fraction of arterial blood volume	http://purl.obolibrary.org/obo/PBPKO_00610	fraction of volume of compartment	farterialblood
scvart	A dimensionless fraction of volume defined as the arterial blood volume divided per unit of total body weight.
https://github.com/Crispae/pbpko/blob/main/pbpko.owl#OWLClass_91922c71_3d34_4be7_afba_308793928193	glomerulus compartment	http://purl.obolibrary.org/obo/PBPKO_00557	kidney compartment	gfr compartment	A part of kidney compartment in the model representing glomerulus in the body
http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	HiSeq series	A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word HiSeq.
http://purl.obolibrary.org/obo/OBI_0003684	Illumina NextSeq series instrument	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	NextSeq series	A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word NextSeq.
http://purl.obolibrary.org/obo/OBI_0003685	Illumina NovaSeq series instrument	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	NovaSeq series	A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word NovaSeq.
http://purl.obolibrary.org/obo/OBI_0002447	suppression subtractive hybridization	http://purl.obolibrary.org/obo/OBI_0000253	artificially induced nucleic acid hybridization	subtractive hybridization	An artificially induced nucleic acid hybridization that is performed to compare gene expression in different cell or tissue types based on normalization and suppression, which creates a subtracted cDNA or genomic DNA library.
http://purl.obolibrary.org/obo/OBI_0002448	differential screening hybridization	http://purl.obolibrary.org/obo/OBI_0000253	artificially induced nucleic acid hybridization	differential screening	An artificially induced nucleic acid hybridization that is performed to identify differentially expressed genes through hybridization of cDNA probes.
http://purl.obolibrary.org/obo/OBI_0002490	medication time value specification	http://purl.obolibrary.org/obo/OBI_0001931	scalar value specification	medication timepoint	A scalar value specification that specifies the point in time that a human participant under investigation self-administers a medication material
http://purl.obolibrary.org/obo/OBI_0002491	medication dose value specification	http://purl.obolibrary.org/obo/OBI_0001931	scalar value specification	medication dose	A scalar value specification that specifies the value of the quantity of a material entity administered to an organism as a treatment
http://purl.obolibrary.org/obo/OBI_0002621	reconstitution assay	http://purl.obolibrary.org/obo/OBI_0000471	study design execution	reconstitution experiment	An assay in which a cellular process is replicated from the bottom-up using isolated components in order to observe how the components work together.
http://purl.obolibrary.org/obo/OBI_0002623	whole metagenome sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	WMS	A DNA sequencing assay that intends to provide information on the DNA sequences of multiple genomes (a metagenome) from different organisms present in the same input sample.
http://purl.obolibrary.org/obo/OBI_0002625	gene knockdown	http://purl.obolibrary.org/obo/OBI_0600043	genetic transformation	gene knock-down	A genetic transformation which reduces the expression of a specific gene or genes in an organism.
http://purl.obolibrary.org/obo/OBI_0002626	RNAi gene knockdown	http://purl.obolibrary.org/obo/OBI_0002625	gene knockdown	RNA interference gene knockdown	A gene knockdown that silences genes through artificially-induced RNA interference. This is accomplished by introducing small double-stranded interfering RNA complementary to the target mRNA to be silenced, which is then cleaved by a ribonuclease.
http://purl.obolibrary.org/obo/OBI_0002628	RNAi knockdown assay	http://purl.obolibrary.org/obo/OBI_0001672	gene knock-down assay	RNAi gene knockdown assay	A gene knockdown assay in which RNAi gene knockdown is used to disrupt gene transcripts.
http://purl.obolibrary.org/obo/OBI_0002629	direct RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0001177	RNA sequencing assay	direct RNA-seq	An assay to study transcription through direct RNA sequence determination, without prior conversion of RNA molecules to cDNA.
http://purl.obolibrary.org/obo/OBI_0002630	Illumina NovaSeq 6000	http://purl.obolibrary.org/obo/OBI_0003685	Illumina NovaSeq series instrument	NovaSeq 6000	A DNA sequencer which is manufactured by the Illumina corporation, with two flow cells and an output of up to 6000 Gb (32-40 B reads per run). The sequencer utilizes synthesis technology and patterned flow cells to optimize throughput and even spacing of sequencing clusters.
http://purl.obolibrary.org/obo/OBI_0002947	fluorescence imaging-based cell proliferation assay	http://purl.obolibrary.org/obo/OBI_0000891	cell proliferation assay	fluorescence imaging-based cell count assay	A type of cell proliferation assay in which fluorescent dyes are ued to label and detect proteins or structures that can be used to count cells.
http://purl.obolibrary.org/obo/OBI_0002956	targeted, drug-modulated, mass spectrometry-based protein phoshporylation-state assay	http://purl.obolibrary.org/obo/OBI_0002955	mass spectrometry-based protein state assay	P100 phosphoprotein quantification assay	A type of mass spectrometry protein state assay that measures levels of a targeted set of proteins in different phosphorylation states in response to drug perturbations.
http://purl.obolibrary.org/obo/OBI_0002957	reverse phase protein array profiling assay	http://purl.obolibrary.org/obo/OBI_0002953	protein state assay	reverse phase lysate array profiling assay	A type of protein state assay where tissue or cell samples are lysed and then spotted onto a slide which is probed with antibodies specific to proteins with and without post-translational modifications.
http://purl.obolibrary.org/obo/OBI_0002958	SWATH-MS protein profiling assay	http://purl.obolibrary.org/obo/OBI_0000615	protein expression profiling assay	sequential window acquisition of all theoretical mass spectra protein profiling assay	A type of mass spectrometry assay using a data-independent acquisition method to identify target peptides.
http://purl.obolibrary.org/obo/OBI_0002961	global chromatin profiling by mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0002020	epigenetic modification assay	global chromatin profiling	A type of epigenetic modification assay that employs targeted quantitative mass spectrometry to profile modifications of the core histones of chromatin.
http://purl.obolibrary.org/obo/OBI_0002965	landmark transcript profiling assay	http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay	L1000 mRNA profiling assay	A type of transcription profiling assay in which a set of landmark transcripts that have been determined to provide a comprehensive profile of cell activity, plus numerous steady-state controls, are assayed via ligation-mediated amplification followed by capture on fluorescently labeled microspheres followed by detection of fluorescence.
http://purl.obolibrary.org/obo/OBI_0002966	microenvironment microarray assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay	MEMA assay	A type of cytometry assay where cells are incubated for three days with a standardized set of extracellular matrix proteins in combination with various ligands creating varying microenvironment perterbations for the cells. Immunofluorescent imaging of cells is used to measure features such as morphology, metabolism, cell cycle, and nuclear activity.
http://purl.obolibrary.org/obo/OBI_0002968	positive/negative ion switching metabolite profiling assay	http://purl.obolibrary.org/obo/OBI_0000366	metabolite profiling assay	positive/negative ion switching metabolomic assay	A type of metabolic profiling assay which employs a hybrid dual quadrupole linear ion trap mass spectrometer for steady-state profiling of endogenous polar metabolites from organic extractions from biological samples.
http://purl.obolibrary.org/obo/OBI_0003031	fluorogenic PCR assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	TaqMan	A polymerase chain reaction assay that uses target specific probes labeled with fluorogenic chromophores.
http://purl.obolibrary.org/obo/OBI_0003033	cleavage under targets and release using nuclease assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	CUT&RUN assay	A type of DNA sequencing assay employing in situ chromatin profiling in which antibody-targeted controlled cleavage by micrococcal nuclease releases specific protein-DNA complexes into the the supernatant for sequencing.
http://purl.obolibrary.org/obo/OBI_0003034	cleavage under targets and tagmentation	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	CUT&Tag assay	A type of DNA sequencing assay employing in situ chromatin profiling in which a chromatin protein is bound in situ by a specific antibody, which then tethers to a protein A-Tn5 hyperactive transposase fusion protein (pA-Tn5) loaded with sequence adapters. Activation of pA-Tn5 results in factor-targeted tagmentation, generating fragments ready for PCR enrichment and DNA sequencing.
http://purl.obolibrary.org/obo/OBI_0003037	malaria rapid diagnosis assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay	malaria rapid diagnosis test	An assay that is quick and easy in the diagnosis of malaria by detecting evidence of malaria parasites (antigens) in human blood.
http://purl.obolibrary.org/obo/OBI_0003039	feces microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	stool test for microorganisms	An organism detection assay that detects microorganisms in a feces specimen.
http://purl.obolibrary.org/obo/OBI_0003048	BG-lure scent dispenser	http://purl.obolibrary.org/obo/OBI_0000968	device	BG-lure	A device manufactured by BioGents that is designed for operation with the BG-Sentinel trap and releases an attractant that mimics the scent of human skin.
http://purl.obolibrary.org/obo/OBI_0003050	Centers for Disease Control and Prevention gravid trap	http://purl.obolibrary.org/obo/OBI_0002929	gravid trap	CDC gravid trap	A gravid trap that consists of a pan holding a hay infusion, motorized fan, and collection bag. This trap is designed to attract gravid female arthropods to the infused material, which would serve as an oviposition medium, and then draw them into the bag with the current generated by the fan.
http://purl.obolibrary.org/obo/OBI_0003051	egg specimen collection process	http://purl.obolibrary.org/obo/OBI_0002907	aquatic arthropod specimen collection process	collection of eggs	An arthropod specimen collection process in which the arthropods are in the embryo stage.
http://purl.obolibrary.org/obo/OBI_0003052	larval specimen collection process	http://purl.obolibrary.org/obo/OBI_0002907	aquatic arthropod specimen collection process	collection of larvae	An arthropod specimen collection process in which the arthropods are in the larval stage.
http://purl.obolibrary.org/obo/OBI_0003053	pupal specimen collection process	http://purl.obolibrary.org/obo/OBI_0002907	aquatic arthropod specimen collection process	collection of pupae	An arthropod specimen collection process in which the arthropods are in the pupal stage.
http://purl.obolibrary.org/obo/OBI_0003054	blood specimen in vacutainer	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen	Vacutainer sample	A blood specimen that is located in a vacutainer.
http://purl.obolibrary.org/obo/OBI_0003055	blood specimen on filter paper	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen	Filter paper sample	A blood specimen that is located on a filter paper.
http://purl.obolibrary.org/obo/OBI_0003077	entomological data item	http://purl.obolibrary.org/obo/IAO_0000027	data item	entomological measurement datum	A data item that is about a collection of insects.
http://purl.obolibrary.org/obo/OBI_0003085	laboratory postal address	http://purl.obolibrary.org/obo/IAO_0000422	postal address	laboratory address	A postal address used as a directive to deliver something to a laboratory.
http://purl.obolibrary.org/obo/OBI_0003114	Illumina MiniSeq	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	MiniSeq	A small benchtop DNA sequencer which is manufactured by the Illumina corporation with integrated cluster generation, sequencing and data analysis. The sequencer accommodates various flow cell configurations and can produce up to 25M single reads or 50M paired-end reads per run.
http://purl.obolibrary.org/obo/IAO_8000002	editors ontology module	http://purl.obolibrary.org/obo/IAO_8000000	ontology module	source ontology module	An ontology module that is intended to be directly edited, typically managed in source control, and typically not intended for direct consumption by end-users.
http://purl.obolibrary.org/obo/IAO_8000005	import ontology module	http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module	import file	A subset ontology module that is intended to be imported from another ontology.
http://purl.obolibrary.org/obo/IAO_8000009	single layer subset ontology module	http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module	ribbon subset	A subset ontology that is largely comprised of a single layer or strata in an ontology class hierarchy. The purpose is typically for rolling up for visualization. The classes in the layer need not be disjoint.
http://purl.obolibrary.org/obo/IAO_8000010	exclusion subset ontology module	http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module	antislim	A subset of an ontology that is intended to be excluded for some purpose. For example, a blacklist of classes.
http://purl.obolibrary.org/obo/IAO_8000011	external import ontology module	http://purl.obolibrary.org/obo/IAO_8000005	import ontology module	external import	An imported ontology module that is derived from an external ontology. Derivation methods include the OWLAPI SLME approach.
http://purl.obolibrary.org/obo/IAO_8000012	species subset ontology module	http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module	taxon subset	A subset ontology that is crafted to either include or exclude a taxonomic grouping of species.
http://purl.obolibrary.org/obo/OBI_0003297	tyramide signal amplification sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	TSA-seq	A DNA sequencing assay that uses tyramide signal amplification (TSA) to assess distance of DNA regions to a targeted nuclear compartment or protein, typically on a scale of 100-1000 nm.
http://purl.obolibrary.org/obo/OBI_0003298	DNA adenine methyltransferase identification assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	DamID assay	An assay for identifying DNA binding sites for a protein by fusing it to Dam methylase, and expressing it so that bound DNA gets methylated. The methylated DNA can then be isolated and analyzed.
http://purl.obolibrary.org/obo/OBI_0003300	nucleolus-associated domain sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	NAD-seq	A DNA sequencing assay in which nucleoli are isolated and the DNA associated with them is sequenced to identify nucleoli-associating domains.
http://purl.obolibrary.org/obo/OBI_0003303	single cell combinatorial indexing Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay	sci-Hi-C	A Hi-C assay performed on massively multiplexed single-cell samples.
http://purl.obolibrary.org/obo/OBI_0003304	single nucleus Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay	sn-Hi-C	A Hi-C assay performed on isolated nuclei.
http://purl.obolibrary.org/obo/OBI_0003307	multi-contact Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay	MC-HI-C	A Hi-C assay that assesses interactions between multiple DNA fragments rather than only pairwise interactions as in traditional Hi-C. The experimental procedure of cross-linking, digestion, and ligation is performed similarly to traditional Hi-C, but after DNA is purified a long-read library is produced in which many ligated fragments may be contained in a single molecule. The library is then sequenced on a long read sequencer.
http://purl.obolibrary.org/obo/OBI_0003309	transposase-mediated analysis of chromatin looping assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	TrAC-Loop	A DNA sequencing assay designed to detect interacting genomic regions. Rather than the traditional Hi-C approach of digestion and proximity ligation, the procedure involves transposase-mediated insertion of an oligonucleotide linker between the pair of interacting regions.
http://purl.obolibrary.org/obo/OBI_0003310	split-pool recognition of interactions and tag extension assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	SPRITE	A sequencing assay designed to detect multi-way interactions between nucleic acids. The procedure involves crosslinking nuclei, and then splitting the lysate among wells in a 96-well or other multi-well plate. A different barcode is ligated to the fragments in each well, and the lysates are pooled together again. This sequence of splitting, tagging, and re-combining is repeated several times so that fragments with the same sequences of barcodes represent fragments that have co-associated throughout the experiment. Finally, a sequencing library is constructed and high-throughput sequencing is performed.
http://purl.obolibrary.org/obo/OBI_0003311	DNA split-pool recognition of interactions and tag extension assay	http://purl.obolibrary.org/obo/OBI_0003310	split-pool recognition of interactions and tag extension assay	DNA SPRITE	A split-pool recognition of interactions and tag extension (SPRITE) assay that only assays interactions between regions of genomic DNA.
http://purl.obolibrary.org/obo/OBI_0003312	RNA-DNA split-pool recognition of interactions and tag extension assay	http://purl.obolibrary.org/obo/OBI_0003310	split-pool recognition of interactions and tag extension assay	RNA-DNA SPRITE	A split-pool recognition of interactions and tag extension (SPRITE) assay in which RNA in the cross-linked complexes is converted to cDNA before the initial splitting step, allowing analysis of RNA-DNA interactions.
http://purl.obolibrary.org/obo/OBI_0003313	genome architecture mapping assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay	GAM	A DNA sequencing assay designed to analyze 3D chromatin structure without relying on digestion and ligation. The procedure involves cryosectioning samples in random orientation, and then single nuclear profiles are isolated by laser microdissection. Each nuclear profile then undergoes high-throughput sequencing, and subsequent analysis can generate a matrix of inferred proximity between genomic regions.
http://purl.obolibrary.org/obo/OBI_0003314	mapping RNA-genome interactions assay	http://purl.obolibrary.org/obo/OBI_0002438	nuclear ligation assay	MARGI	A nuclear ligation assay for probing RNA-DNA interactions in the nucleus. Nuclei are crosslinked, and RNA fragments are ligated to proximal DNA fragments via a special linker molecule. After reverse transcription, high-throughput sequencing is performed.
http://purl.obolibrary.org/obo/OBI_0003374	remote patient assessment	http://purl.obolibrary.org/obo/OBI_0003366	organism diagnostic process	telehealth patient assessment	An organism diagnostic process which involves a remote assessment of a patient by a clinician.
http://purl.obolibrary.org/obo/CHMO_0000087	fluorescence microscopy assay	http://purl.obolibrary.org/obo/CHMO_0000102	light microscopy assay	fluorescence microscopic imaging	Any type of light microscopy assay where the specimen can be made to fluoresce (emit energy as visible light) by illuminating it with light of specific wavelengths. These specimens are called fluorophores.
http://purl.obolibrary.org/obo/CHMO_0000089	confocal fluorescence microscopy assay	http://purl.obolibrary.org/obo/OBI_0002119	microscopy assay	scanning confocal fluorescence microscopy	Microscopy where the specimen can be made to fluoresce (emit energy as visible light) by scanning a gas (Ar or Kr) laser spot of specific wavelength over its surface and using a spatial pinhole to eliminate out-of-focus fluorescence.
http://purl.obolibrary.org/obo/CHMO_0000102	light microscopy assay	http://purl.obolibrary.org/obo/OBI_0002119	microscopy assay	optical microscopy	Microscopy where the specimen is illuminated with visible light and a system of lenses is used to produce an image.
http://purl.obolibrary.org/obo/CHMO_0000701	liquid chromatography-tandem mass spectrometry	http://purl.obolibrary.org/obo/OBI_0003540	tandem mass spectrometry assay	liquid chromatography-tandem mass spectroscopy	A method where a sample mixture is first separated by liquid chromatography before being ionised and characterised by mass-to-charge ratio and relative abundance using two mass spectrometers in series.
http://purl.obolibrary.org/obo/OBI_0002598	inverse polymerase chain reaction	http://purl.obolibrary.org/obo/OBI_0000415	polymerase chain reaction	inverse PCR	A polymerase chain reaction which amplifies DNA with only one known sequence from which primers may be designed. A series of restriction digestions and ligations result in a looped DNA fragment which can be primed for PCR.
http://purl.obolibrary.org/obo/OBI_0003287	multiplex real time polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0000893	real time polymerase chain reaction assay	multiplexed real time polymerase chain reaction assay	A real time polymerase chain reaction assay in which multiple DNA sequences are amplified in a single cycle.
http://purl.obolibrary.org/obo/OBI_0003288	multiplex real time reverse-transcription polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0000911	real time reverse-transcription polymerase chain reaction assay	multiplexed real time reverse-transcription polymerase chain reaction assay	A real time reverse-transcription polymerase chain reaction assay in which multiple DNA sequences are amplified in a single cycle.
http://purl.obolibrary.org/obo/OBI_0003296	antibodies from lymphocyte secretions assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay	antibodies from lymphocyte supernatant assay	An assay that evaluates a blood specimen for antibodies currently being produced by lymphocytes in the specimen, by separating peripheral blood mononuclear cells, culturing them, and then collecting the supernatant containing the antibodies secreted from those cells.
http://purl.obolibrary.org/obo/OBI_0003087	autofluorescence assay	http://purl.obolibrary.org/obo/OBI_0001501	fluorescence detection assay	intrinsic fluorescence assay	A fluorescence detection assay in which the light that is naturally emitted by a sample is visualized after excitation of the sample with light at a suitable wavelength.
http://purl.obolibrary.org/obo/OBI_0003089	bulk assay for transposase-accessible chromatin using sequencing	http://purl.obolibrary.org/obo/OBI_0002039	assay for transposase-accessible chromatin using sequencing	bulk ATAC-seq	An assay for transposase-accessible chromatin using sequencing in which the sample that is sequenced is derived from a collection of cells, such as a tissue sample or entire cell culture, and therefore provides results representative of the aggregate of sample cells.
http://purl.obolibrary.org/obo/OBI_0003093	co-detection by indexing assay	http://purl.obolibrary.org/obo/OBI_0003091	multiplexed fluorescent antibody imaging assay	CODEX	A multiplexed fluorescent antibody imaging assay that involves a highly multiplexed analysis of up to 40 proteins in a tissue using cyclic detection of DNA-indexed antibody panels.
http://purl.obolibrary.org/obo/OBI_0003094	fluorescence in-situ hybridization assay	http://purl.obolibrary.org/obo/OBI_0001686	in-situ hybridization assay	FISH	An in-situ hybridization assay in which fluorescently labeled molecules are used to localize specific DNA or RNA sequences.
http://purl.obolibrary.org/obo/OBI_0003095	decoding amplified targeted transcripts with fluorescence in situ hybridization assay	http://purl.obolibrary.org/obo/OBI_0003094	fluorescence in-situ hybridization assay	DARTFISH	A fluorescence in-situ hybridization assay which involves multiplex in situ digital quantification of targeted RNA transcripts in fresh or frozen tissue providing an understanding of the spatial organization of different cell types.
http://purl.obolibrary.org/obo/OBI_0003096	imaging mass cytometry assay	http://purl.obolibrary.org/obo/OBI_0002115	cytometry time of flight assay	imaging CyTOF	A cytometry time of flight assay in which molecules of interest on or in cells are imaged through a system in which samples are labeled with multiple different rare-earth tagged antibodies. The sample is then ablated with a laser and the labeled material is detected by cytometry time of flight mass spectrometry.
http://purl.obolibrary.org/obo/OBI_0003097	liquid chromatography mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0000470	mass spectrometry assay	LC-MS	A mass spectrometry assay where a sample mixture is first separated by liquid chromatography before being converted into ions which are characterized by using mass spectrometry based on their mass-to-charge ratio and relative abundance.
http://purl.obolibrary.org/obo/OBI_0003099	matrix assisted laser desorption ionization imaging mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0000470	mass spectrometry assay	MALDI-IMS	A mass spectrometry assay that involves collection of spatially resolved mass spectra of a sample during microscopy where a pulse laser is used to produce both ionisation and vaporization. The sample is held in a matrix (such as dihydrobenzoic acid) to protect it from direct laser illumination and to separate the sample molecules. The spectra are used to visualise the spatial distribution of biomolecules by their molecular masses.
http://purl.obolibrary.org/obo/OBI_0003100	multiplexed ion beam imaging assay	http://purl.obolibrary.org/obo/OBI_0002115	cytometry time of flight assay	MIBI	A cytometry time of flight assay in which molecules of interest on or in cells are imaged through a system in which samples are labeled with multiple different rare-earth tagged antibodies. A primary ion beam is ued to rasterize sections under vacuum, releasing showers of secondary ions detected by cytometry time of flight mass spectrometry.
http://purl.obolibrary.org/obo/OBI_0003101	nanospray desorption electrospray ionization assay	http://purl.obolibrary.org/obo/OBI_0000470	mass spectrometry assay	NanoDESI	A mass spectrometry assay that analyzes organic and biological molecules on a substrate by desorption of an analyte into a solvent bridge formed between two capillaries and the analysis surface. One capillary supplies solvent to create and maintain the bridge, while the second capillary transports the dissolved analyte from the bridge to the mass spectrometer. A high voltage applied between the inlet of mass spectrometer and the primary capillary creates a self-aspirating nanospray.
http://purl.obolibrary.org/obo/OBI_0003102	nanodroplet processing in one pot for trace samples assay	http://purl.obolibrary.org/obo/OBI_0000615	protein expression profiling assay	NanoPOTS	A protein expression profiling assay in which proteomics sample processing is performed in nanoliter volumes. Flow cytometry or laser microdissection is employed to isolate a small population or single cells into a nanoPOTS chip. Then, liquid chromatography mass spectrometry is used to measure the global protein expression.
http://purl.obolibrary.org/obo/OBI_0003103	periodic acid-Schiff staining assay	http://purl.obolibrary.org/obo/OBI_0600020	histological assay	PAS staining	A histological assay which is used on tissue samples to demonstrate the presence of carbohydrates and carbohydrate compounds such as polysaccharides, mucin, glycogen, or fungal cell wall components.
http://purl.obolibrary.org/obo/OBI_0003104	single cell combinatorial indexing assay for transposase-accessessable chromatin using sequencing	http://purl.obolibrary.org/obo/OBI_0002039	assay for transposase-accessible chromatin using sequencing	sciATACseq	An assay for transposase-accessible chromatin that uses sequencing which involves single cell combinatorial indexing ('sci-') strategy where nucleic acids from each of many cells are uniquely tagged through several rounds of split-pool barcoding which enables identification of single cells without single cell isolation.
http://purl.obolibrary.org/obo/OBI_0003105	single-cell combinatorial indexing RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0002631	single-cell RNA sequencing assay	sciRNAseq	A single-cell RNA sequencing assay that involves single cell combinatorial indexing ('sci-') strategy to profile the transcriptomes of single cells or nuclei without single cell isolation.
http://purl.obolibrary.org/obo/OBI_0003106	sequential fluorescence in-situ hybridization assay	http://purl.obolibrary.org/obo/OBI_0003094	fluorescence in-situ hybridization assay	seqFISH	A fluorescence in-situ hybridization assay that involves ultra-resolution imaging of cell activity by targetting thousands of single molecules with fluorescent probes which find and hybridize with complementary DNA or RNA sequences in the tissue sample, thus enabling identification of those molecules directly in single cells with their spatial context preserved.
http://purl.obolibrary.org/obo/OBI_0003108	single-nucleus chromatin accessibility and mRNA expression sequencing assay	http://purl.obolibrary.org/obo/OBI_0003109	single-nucleus RNA sequencing assay	SNAREseq	A single-nucleus RNA sequencing assay that involves joint profiling of accessible chromatin and RNA within the same cells which enables direct matching of transcriptional regulation to its outputs.
http://purl.obolibrary.org/obo/OBI_0003109	single-nucleus RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	snRNA-seq	A RNA-seq assay that is used for profiling gene expression in individual nuclei with optimized next generation sequencing (NGS) technologies. This allows the RNA-seq profiling of cell types that are more vulnerable to the tissue dissociation process, and that are therefore underrepresented in the final data set in single cell sequencing.
http://purl.obolibrary.org/obo/OBI_0003110	gas chromatography mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0000470	mass spectrometry assay	GC-MS	A mass spectrometry assay combining mass spectrometry and gas chromatography for the qualitative as well as quantitative determination of compounds.
http://purl.obolibrary.org/obo/OBI_0003125	mosaicism with repeat frameshift genetic sparse labeling	http://purl.obolibrary.org/obo/OBI_0003123	3D neural cell structure determination assay	MORF genetic sparse labeling	A 3D neural cell structure determination assay where sparse and stochastic methods are used to label genetically-defined neurons.
http://purl.obolibrary.org/obo/OBI_0003130	irradiation mutagenesis	http://purl.obolibrary.org/obo/OBI_0002620	random mutagenesis	radiation induced mutagenesis	A form of random mutagenesis that produces a random mutation by exposing the organism to radiation.
http://purl.obolibrary.org/obo/OBI_0003133	cas mediated mutagenesis	http://purl.obolibrary.org/obo/OBI_0003132	endonuclease mediated mutagenesis	CRISPR/cas mediated mutagenesis	An endonuclease mediated mutagenesis in which guide RNAs and cas are used to introduce a mutation at a specific location in the genome.
http://purl.obolibrary.org/obo/OBI_0003135	zinc finger mediated mutagenesis	http://purl.obolibrary.org/obo/OBI_0003132	endonuclease mediated mutagenesis	ZFN mediated mutagenesis	An endonuclease mediated mutagenesis in which synthetic zinc-finger proteins designed to target specific DNA sequences are used to introduce a mutation at a specific location in the genome.
http://purl.obolibrary.org/obo/OBI_0003139	targeted mutagenesis	http://purl.obolibrary.org/obo/OBI_0003131	directed mutagenesis	gene targeting by homologous recombination	A directed mutation in which a construct is used to introduce a mutation into a specific genome location through homologous recombination.
http://purl.obolibrary.org/obo/OBI_0003141	categorical binding datum	http://purl.obolibrary.org/obo/OBI_0001181	binding datum	qualitative binding datum	A binding datum that is expressed as a categorical value.
http://purl.obolibrary.org/obo/OBI_0003228	fluorescent immunospot assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay	FLUOROSPOT	A cytometry assay that detects the presence of cells that secrete a material of interest (analyte). In the assay, a plate is coated with an antibody specific to the analyte of interest. These antibodies capture the analytes secreted by the cells. The analytes are then detected using fluorescent labeled secondary antibodies.
http://purl.obolibrary.org/obo/OBI_0003657	minimum resolved unit of measurement	http://purl.obolibrary.org/obo/IAO_0000030	information content entity	least count	An information content entity that indicates the smallest increment that can be resolved on the scale of a measurement instrument.
http://purl.obolibrary.org/obo/OBI_0003705	study arm design	http://purl.obolibrary.org/obo/IAO_0000104	plan specification	study arm design	A plan specification that is part of a study design, executed as part of an investigation, and realized by assigning participants under investigation to a study design.
http://purl.obolibrary.org/obo/OBI_0003706	study arm population	http://purl.obolibrary.org/obo/OBI_0000181	population	study arm population	A population of organisms that are participants under investigation in the same study design execution.
http://purl.obolibrary.org/obo/OBI_0002190	courier organization	http://purl.obolibrary.org/obo/OBI_0000245	organization	courier	An organization that delivers messages, packages, and mail.
http://purl.obolibrary.org/obo/OBI_0002198	molecular analysis facility organization	http://purl.obolibrary.org/obo/OBI_0000245	organization	MAF	An organization that provides molecular analysis service.
http://purl.obolibrary.org/obo/OBI_0002200	cannot be assessed determination	http://purl.obolibrary.org/obo/OBI_0002199	reason for lack of data item	cannot be assessed	A reason for lack of data item that is the negative output of a determination if assay will provide reliable results.
http://purl.obolibrary.org/obo/OBI_0002210	histologic grade according to the Fuhrman Nuclear Grading System	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Histologic Grade (Fuhrman Nuclear Grading System)	A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the Fuhrman Nuclear Grading System.
http://purl.obolibrary.org/obo/OBI_0002224	pathologic primary tumor stage for colon and rectum according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread colorectal primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002232	pathologic primary tumor stage for lung according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread lung primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM American Joint Committee on Cancer (AJCC) version 7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002243	pathologic primary tumor stage for kidney according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread kidney primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002256	pathologic primary tumor stage for ovary according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pT: Pathologic spread ovarian primary tumor (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of the primary tumor. TNM pathologic primary tumor findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002270	pathologic lymph node stage for colon and rectum according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of colorectal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002279	pathologic lymph node stage for lung according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread colon lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002284	pathologic lymph node stage for kidney according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread kidney lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002287	pathologic lymph node stage for ovary according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	pN: Pathologic spread ovarian lymph nodes (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to staging of regional lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002290	pathologic distant metastases stage for colon according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: colon distant metastases (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of colon cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002298	pathologic distant metastases stage for lung according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: lung distant metastases (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of lung cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002306	pathologic distant metastases stage for kidney according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: kidney distant Metastases (AJCC 7th Edition)	A categorical value specification that is a pathologic finding about one or more characteristics of renal cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002310	pathologic distant metastases stage for ovary according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	M: ovarian distant metastases (AJCC 7th Edition)	A categorical value specification that is a  pathologic finding about one or more characteristics of ovarian cancer following the rules of the TNM AJCC v7 classification system as they pertain to distant metastases. TNM pathologic distant metastasis findings are based on clinical findings supplemented by histopathologic examination of one or more tissue specimens acquired during surgery.
http://purl.obolibrary.org/obo/OBI_0002314	clinical tumor stage group according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Clinical tumor stage group (AJCC 7th Edition)	A categorical value specification that is an assessment of the stage of a cancer according to the American Joint Committee on Cancer (AJCC) v7 staging systems.
http://purl.obolibrary.org/obo/OBI_0002326	International Federation of Gynecology and Obstetrics cervical cancer stage value specification	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Clinical FIGO stage	A categorical value specification that is an assessment of the stage of a gynecologic cancer according to the International Federation of Gynecology and Obstetrics (FIGO) staging systems.
http://purl.obolibrary.org/obo/OBI_0002341	International Federation of Gynecology and Obstetrics ovarian cancer stage value specification	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Pathologic Tumor Stage Grouping for ovarian cancer (FIGO)	A categorical value specification that is a pathologic finding about one or more characteristics of ovarian cancer following the rules of the FIGO classification system.
http://purl.obolibrary.org/obo/OBI_0002356	performance status value specification	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification	Performance Status Scale	A categorical value specification that is an assessment of a participant's performance status (general well-being and activities of daily life).
http://purl.obolibrary.org/obo/OBI_0002357	Eastern Cooperative Oncology Group score value specification	http://purl.obolibrary.org/obo/OBI_0002356	performance status value specification	ECOG score	A performance status value specification designed by the Eastern Cooperative Oncology Group to assess disease progression and its affect on the daily living abilities of the patient.
http://purl.obolibrary.org/obo/OBI_0002363	Karnofsky score vaue specification	http://purl.obolibrary.org/obo/OBI_0002356	performance status value specification	Karnofsky Score	A performance status value specification designed for classifying patients 16 years of age or older by their functional impairment.
http://purl.obolibrary.org/obo/OBI_0002369	clinical history devoid of cancer	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history	clinical history of no cancer	A clinical history in which there was no diagnosis of cancer.
http://purl.obolibrary.org/obo/OBI_0002371	diagnosis of cancer	http://purl.obolibrary.org/obo/OGMS_0000073	diagnosis	cancer diagnosis	A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has cancer.
http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history	family history of cancer	A clinical history in which there is a diagnosis of cancer in a blood relative.
http://purl.obolibrary.org/obo/OBI_0002406	delivery form for hormonal replacement therapy	http://purl.obolibrary.org/obo/OBI_0000047	processed material	form of hormone replacement therapy	A processed material used for delivery of hormones in hormone replacement therapy.
http://purl.obolibrary.org/obo/OBI_0002421	indicator of whether an inclusion criterion was met	http://purl.obolibrary.org/obo/IAO_0000030	information content entity	eligibility criterion met	An information content entity that indicates whether or not  an entity has met a specific requirement in order to take part in a given process.
http://purl.obolibrary.org/obo/OBI_0002422	indicator of whether all inclusion criteria were met	http://purl.obolibrary.org/obo/IAO_0000030	information content entity	all eligibility criteria met	An information content entity  that indicates whether or not  an entity  has met all specific requirements in order to take part in a given process.
http://purl.obolibrary.org/obo/OBI_0002437	widefield microscopy assay	http://purl.obolibrary.org/obo/CHMO_0000087	fluorescence microscopy assay	WFM	A fluorescence microscopy technique where the specimen under investigation is fully bathed in light, as opposed to confocal microscopy in which only a small portion of the specimen is illuminated.
http://purl.obolibrary.org/obo/OBI_0002439	chromosome conformation capture assay	http://purl.obolibrary.org/obo/OBI_0002438	nuclear ligation assay	3C assay	A nuclear ligation assay that detects chromosomal interactions between any two genomic loci. Chromatin segments are cross-linked, cut by restriction enzymes, ligated, and finally analyzed by PCR.
http://purl.obolibrary.org/obo/OBI_0002443	methidiumpropyl-EDTA-iron(II) footprinting assay	http://purl.obolibrary.org/obo/OBI_0002162	footprinting assay	MPE-Fe(II) footprinting	A footprinting assay that determines protein-binding sites on DNA by partial cleavage of ligand-protected DNA restriction fragments with methidium-propyl-EDTA (MPE). MPE-Fe(II) in the presence of oxygen efficiently catalyzes the non-specific clevage of DNA.
http://purl.obolibrary.org/obo/OBI_0002631	single-cell RNA sequencing assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay	scRNA-seq	An RNA sequencing assay that uses RNA extracts as input that can be traced to a single cell of origin.
http://purl.obolibrary.org/obo/OBI_0002632	PacBio Sequel	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	Pacific BioSciences Sequel	A DNA sequencer built upon single molecule real-time sequencing technology, optimized for generation with long reads and high consensus accuracy, and manufactured by the Pacific Biosciences corporation
http://purl.obolibrary.org/obo/OBI_0002633	PacBio Sequel II	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	Pacific BioSciences Sequel II	A DNA sequencer built upon single molecule real-time sequencing technology, optimized for generation of highly accurate ("HiFi") long reads, and which is manufactured by the Pacific Biosciences corporation.
http://purl.obolibrary.org/obo/OBI_0002673	enrichment culture medium	http://purl.obolibrary.org/obo/OBI_0000079	culture medium	isolation medium	A culture medium that is designed to favor the growth of a particular microorganism or cells over others, enriching a sample for the microorganism or cells of interest.
http://purl.obolibrary.org/obo/OBI_0002675	massively parallel reporter assay	http://purl.obolibrary.org/obo/OBI_0002082	reporter gene assay	MPRA	An assay in which multiplexing the construction and interrogation of larger libraries of reporter constructs allows measurement of the transcriptional regulatory activities of thousands to hundreds of thousands of DNA sequences.
http://purl.obolibrary.org/obo/OBI_0002680	pseudovirus entry assay	http://purl.obolibrary.org/obo/OBI_0001187	infectious agent detection assay	pseudovirus cell entry	An assay that measures the entry in target cells of reporter viral particles that express an envelope protein of a different virus of interest.
http://purl.obolibrary.org/obo/OBI_0002683	short interspersed nuclear elements polymerase chain reaction	http://purl.obolibrary.org/obo/OBI_0000415	polymerase chain reaction	short interspersed elements PCR	A polymerase chain reaction that amplifies short interspersed nuclear elements (SINEs).
http://purl.obolibrary.org/obo/OBI_0002684	nested polymerase chain reaction	http://purl.obolibrary.org/obo/OBI_0000415	polymerase chain reaction	nested-PCR	A polymerase chain reaction with modification intended to reduce non-specific binding in products due to the amplification of unexpected primer binding sites. The nested polymerase chain reaction (PCR) involves the use of two primer sets and two successive PCR reactions. The first set of primers are designed to anneal to sequences upstream from the second set of primers and are used in an initial PCR reaction.
http://purl.obolibrary.org/obo/OBI_0002685	immunoelectrophoresis	http://purl.obolibrary.org/obo/OBI_0600053	electrophoresis	IEP	An electrophoresis that separates and characterize proteins based on reaction with antibodies.
http://purl.obolibrary.org/obo/OBI_0002687	ligase detection reaction	http://purl.obolibrary.org/obo/OBI_0001494	linear amplification	LDR	A linear amplification that uses a thermostable ligase to amplify a piece of DNA. Because the enzyme retains activity after multiple thermal cycles, the ligations may be repeated to linearly increase product.
http://purl.obolibrary.org/obo/OBI_0002688	loop-mediated isothermal amplification	http://purl.obolibrary.org/obo/OBI_0600058	enzymatic amplification	LAMP	An enzymatic amplification in which a piece of DNA is amplified at a constant temperature of 60 - 65 degree C using either two or three sets of primers and a polymerase with high strand displacement activity in addition to a replication activity. This amplification does not need thermal cyclers and may be a low cost alternative to PCR.
http://purl.obolibrary.org/obo/OBI_0002691	arthropod meal of blood specimen	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen	blood meal	A specimen of the blood ingested by an arthropod.
http://purl.obolibrary.org/obo/OBI_0002693	restriction fragment length polymorphism assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	restriction fragment length polymorphism analysis	An assay that uses digestion of DNA with specific restriction enzymes followed by gel electropheresis to detect differences in the sizes of the generated fragments that are due to genetic differences (polymorphisms) in homologous sequences.
http://purl.obolibrary.org/obo/OBI_0002694	DNA fingerprinting assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	DNA fingerprint	An assay to identify a specific individual organism from a DNA specimen by looking at unique patterns in their DNA.
http://purl.obolibrary.org/obo/OBI_0002695	insecticide resistance assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	resistance identification/monitoring	An assay that aims to detect the presence and/or frequency of resistance to insecticides in an organism or organism population.
http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay	http://purl.obolibrary.org/obo/OBI_0002695	insecticide resistance assay	monitoring known mutations	An insecticide resistance assay that detects, in a population, presence and frequency of mutant alleles for previously characterized mutations with insecticide resistance phenotypes.
http://purl.obolibrary.org/obo/OBI_0002697	insecticide resistance by detecting enzyme activity assay	http://purl.obolibrary.org/obo/OBI_0002695	insecticide resistance assay	metabolic resistance assay	An insecticide resistance assay that is based on determination the catalytic activity of an enzyme associated with insecticide resistance phenotypes.
http://purl.obolibrary.org/obo/OBI_0002698	insecticide resistance bioassay	http://purl.obolibrary.org/obo/OBI_0002695	insecticide resistance assay	bioassay	An insecticide resistance assay that is typically conducted to measure the effects of a substance on a living organism.
http://purl.obolibrary.org/obo/OBI_0002699	insecticide resistance by detecting alpha esterase activity assay	http://purl.obolibrary.org/obo/OBI_0002697	insecticide resistance by detecting enzyme activity assay	alpha esterase activity assay	An insecticide resistance by detecting enzyme activity assay that measures activity of alpha esterase.
http://purl.obolibrary.org/obo/OBI_0002700	insecticide resistance by detecting beta esterase activity assay	http://purl.obolibrary.org/obo/OBI_0002697	insecticide resistance by detecting enzyme activity assay	beta esterase activity assay	An insecticide resistance by detecting enzyme activity assay that measures activity of beta esterase.
http://purl.obolibrary.org/obo/OBI_0002701	insecticide resistance by detecting acetylcholinesterase activity assay	http://purl.obolibrary.org/obo/OBI_0002697	insecticide resistance by detecting enzyme activity assay	acetylcholinesterase assay	An insecticide resistance by detecting enzyme activity assay that measures activity of acetylcholinesterase.
http://purl.obolibrary.org/obo/OBI_0002702	insecticide resistance by detecting glutathione S-transferase activity assay	http://purl.obolibrary.org/obo/OBI_0002697	insecticide resistance by detecting enzyme activity assay	GST related assay	An insecticide resistance by detecting enzyme activity assay that measures activity of glutathione S-transferase (GST).
http://purl.obolibrary.org/obo/OBI_0002703	insecticide resistance by detecting carboxylic ester hydrolase activity assay	http://purl.obolibrary.org/obo/OBI_0002697	insecticide resistance by detecting enzyme activity assay	pNPA assay	An insecticide resistance by detecting enzyme activity assay that measures activity of carboxylic ester hydrolase using p-nitrophenyl acetate as a substrate.
http://purl.obolibrary.org/obo/OBI_0002704	insecticide resistance by detecting mixed-function oxidase assay	http://purl.obolibrary.org/obo/OBI_0002697	insecticide resistance by detecting enzyme activity assay	mixed-function oxidase assay	An insecticide resistance by detecting enzyme activity assay that measures whether mixed-function oxidase activity present.
http://purl.obolibrary.org/obo/OBI_0002705	direct insecticide resistance bioassay	http://purl.obolibrary.org/obo/OBI_0002698	insecticide resistance bioassay	direct bioassay	An insecticide resistance bioassay without the use of any synergist.
http://purl.obolibrary.org/obo/OBI_0002706	topical application insecticide resistance bioassay	http://purl.obolibrary.org/obo/OBI_0002698	insecticide resistance bioassay	topical application assay	An insecticide resistance bioassay by adding insecticide directly to the thorax of the insect.
http://purl.obolibrary.org/obo/OBI_0002707	direct insecticide resistance diagnostic assay	http://purl.obolibrary.org/obo/OBI_0002705	direct insecticide resistance bioassay	diagnostic test	A direct insecticide resistance assay that at preset insecticide dosage scoring mortality to determine resistance of a population.
http://purl.obolibrary.org/obo/OBI_0002708	insecticide resistance dose response assay	http://purl.obolibrary.org/obo/OBI_0002705	direct insecticide resistance bioassay	dose response test	A direct insecticide resistance assay in which an insect population is exposed to a range of insecticide dosage scoring mortality to determine resistance.
http://purl.obolibrary.org/obo/OBI_0002709	insecticide resistance time response assay	http://purl.obolibrary.org/obo/OBI_0002705	direct insecticide resistance bioassay	time response test	A direct insecticide resistance assay to determine resistance as a consequence of the time of exposure to insecticide.
http://purl.obolibrary.org/obo/OBI_0002710	Centre for Disease Control and Prevention bottle bioassay	http://purl.obolibrary.org/obo/OBI_0002707	direct insecticide resistance diagnostic assay	CDC bottle bioassay	A direct insecticide resistance diagnostic assay performs in a glass bottle coated with insecticides for detecting resistance to insecticides in vector populations.
http://purl.obolibrary.org/obo/OBI_0002711	WHO cone kit diagnostic assay	http://purl.obolibrary.org/obo/OBI_0002707	direct insecticide resistance diagnostic assay	cone DT	A direct insecticide resistance diagnostic assay uses WHO cone kit.
http://purl.obolibrary.org/obo/OBI_0002712	WHO paper kit diagnostic assay	http://purl.obolibrary.org/obo/OBI_0002707	direct insecticide resistance diagnostic assay	WHO paper kit DT	A direct insecticide resistance diagnostic assay uses WHO paper kit.
http://purl.obolibrary.org/obo/OBI_0002713	WHO larvicide diagnostic assay	http://purl.obolibrary.org/obo/OBI_0002707	direct insecticide resistance diagnostic assay	WHO larvicide DT	A direct insecticide resistance diagnostic assay tests survival of larvae in a medium supplemented with insecticide.
http://purl.obolibrary.org/obo/OBI_0002714	insecticide resistance dose response by bottle assay	http://purl.obolibrary.org/obo/OBI_0002708	insecticide resistance dose response assay	bottle bioassay DR test	An insecticide resistance dose response assay that performs in a glass bottle coated with insecticides.
http://purl.obolibrary.org/obo/OBI_0002715	insecticide resistance dose response by survival of larvae assay	http://purl.obolibrary.org/obo/OBI_0002708	insecticide resistance dose response assay	WHO larvicide DR test	An insecticide resistance dose response assay that tests survival of larvae in a medium supplemented with insecticide.
http://purl.obolibrary.org/obo/OBI_0002716	insecticide resistance dose response by WHO paper kit assay	http://purl.obolibrary.org/obo/OBI_0002708	insecticide resistance dose response assay	WHO paper kit DR test	An insecticide resistance dose response assay using WHO paper kit.
http://purl.obolibrary.org/obo/OBI_0002717	insecticide resistance time response by bottle assay	http://purl.obolibrary.org/obo/OBI_0002709	insecticide resistance time response assay	bottle bioassay TR test	An insecticide resistance time response assay that is performed in a glass bottle coated with insecticides, with the presence of a synergist.
http://purl.obolibrary.org/obo/OBI_0002718	insecticide resistance time response by WHO paper kit assay	http://purl.obolibrary.org/obo/OBI_0002709	insecticide resistance time response assay	WHO paper kit TR test	An insecticide resistance time response assay using WHO paper kit, with the presence of a synergist.
http://purl.obolibrary.org/obo/OBI_0002719	insecticide resistance by amplification refractory mutation system assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay	Amplification Refractory Mutation System	An insecticide resistance by monitoring known mutations assay that detects any mutation involving single base changes or small deletions using amplification refractory mutation system (ARMS). The ARMS is based on the use of sequence-specific PCR primers that allow amplification of test DNA only when the target allele is contained within the sample. Following an ARMS reaction the presence or absence of a PCR product is diagnostic for the presence or absence of the target allele. It can be used to analyze human genomic DNA for one or more mutations.
http://purl.obolibrary.org/obo/OBI_0002720	insecticide resistance by primer introduced restriction analysis PCR assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay	polymerase chain reaction-primer-introduced restriction analysis	An insecticide resistance by monitoring known mutations assay that detects Single Nucleotide Polymorphisms (SNPs) using PCR technique and mismatched primers that is close to the mutation of interest and digested the PCR productions using restriction enzymes.
http://purl.obolibrary.org/obo/OBI_0002721	insecticide resistance by nested polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay	gene mutation detection by nested PCR	An insecticide resistance by monitoring known mutations assay that detects gene mutation based on nested polymerase chain reaction technique.
http://purl.obolibrary.org/obo/OBI_0002723	insecticide resistance by ligase detection reaction-fluorescent microsphere assay	http://purl.obolibrary.org/obo/OBI_0002722	insecticide resistance by ligase detection reaction assay	gene mutation detection by LDR-FMA	An insecticide resistance by ligase detection reaction assay that uses fluorescently labeled conserved probes in ligase detection reaction.
http://purl.obolibrary.org/obo/OBI_0002724	insecticide resistance by PCR amplification of specific alleles assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay	allele-specific amplification and amplification refractory mutation system	An insecticide resistance assay that is based on monitoring known mutations by PCR amplification of specific alleles to detect polymorphic or mutant alleles.
http://purl.obolibrary.org/obo/OBI_0002726	insecticide resistance by PCR-RFLP assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay	PCR-RFLP	An insecticide resistance by monitoring known mutations assay based on restriction fragment length polymorphism assay.
http://purl.obolibrary.org/obo/OBI_0002727	insecticide resistance by short interspersed elements PCR assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay	Short Interspersed Elements PCR	An insecticide resistance assay that is based on monitoring known mutations by PCR amplification of short interspersed elements (SINEs).
http://purl.obolibrary.org/obo/OBI_0002728	pathogen detection assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	pathogen detection method	An organism detection assay that detects pathogens.
http://purl.obolibrary.org/obo/OBI_0002729	VectorTest assay	http://purl.obolibrary.org/obo/OBI_0002728	pathogen detection assay	VectorTest	A pathogen detection assay that identifies the presence or absence of specific peptide epitopes of circumsporozoite (CS) protein of the most important Plasmodium falciparum and two strains (variants 210 and 247) of the more widespread Plasmodium vivax using a dipstick wicking test strip.
http://purl.obolibrary.org/obo/OBI_0002730	pathogen detection by Rapid Analyte Measurement Platform assay	http://purl.obolibrary.org/obo/OBI_0002728	pathogen detection assay	Rapid Analyte Measurement Platform	A pathogen detection assay that is based on Rapid Analyte Measurement Platform (RAMP) technology to quantify immunologically active substances.
http://purl.obolibrary.org/obo/OBI_0002731	pathogen detection by loop-mediated isothermal amplification assay	http://purl.obolibrary.org/obo/OBI_0002728	pathogen detection assay	Loop-mediated isothermal amplification	A pathogen detection assay that is based on loop-mediated isothermal amplification.
http://purl.obolibrary.org/obo/OBI_0002732	blood meal assay	http://purl.obolibrary.org/obo/OBI_0000070	assay	blood meal analysis	An assay that analyzes the specimen taken from blood meal fed organism, such as insect.
http://purl.obolibrary.org/obo/OBI_0002733	blood meal by counter current immunoelectrophoresis assay	http://purl.obolibrary.org/obo/OBI_0002732	blood meal assay	countercurrent immunoelectrophoresis	A blood meal assay that uses a counter current immunoelectrophoresis technique.
http://purl.obolibrary.org/obo/OBI_0002734	DNA based blood meal finger printing assay	http://purl.obolibrary.org/obo/OBI_0002732	blood meal assay	DNA based blood meal finger printing	A DNA fingerprinting assay that uses DNA extracted from blood meal fed organism, such as insect.
http://purl.obolibrary.org/obo/OBI_0002735	organism detection by size assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	by size	An organism detection assay that is based on the size of organism.
http://purl.obolibrary.org/obo/OBI_0002736	organism detection by cross mating assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	cross mating experiment	An organism detection assay that is based on genetic crossings between specimens collected in the field to determine whether fertile progeny is produced.
http://purl.obolibrary.org/obo/OBI_0002737	organism detection by cytological chromosome examination assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	cytological chromosome examination	An organism detection assay that is based on analysis of polytene chromosomes through cytological examination of the banding pattern of the species.
http://purl.obolibrary.org/obo/OBI_0002738	organism detection by isoenzyme electrophoresis assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	isoenzyme electrophoresis	An organism detection assay that is based on electrophoresis to determine the isozymes that are present in a specific population to determine the species.
http://purl.obolibrary.org/obo/OBI_0002739	organism detection by morphological examination assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	morphological examination	An organism detection assay that is based on examination of morphology and the use of specific taxonomic keys to determine the species of the specimen.
http://purl.obolibrary.org/obo/OBI_0002740	organism detection by PCR assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	PCR-based species identification	An organism detection assay that is based on PCR.
http://purl.obolibrary.org/obo/OBI_0002741	organism detection by specific DNA hybridization assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	species specific DNA hybridization	An organism detection assay that is based on DNA hybrdization.
http://purl.obolibrary.org/obo/OBI_0002742	organism detection by salinity tolerance assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	salinity tolerance tests	An organism detection assay of mosquito species that is on the basis of mosquito survival depending on the salt concentration in the water used to lay their eggs to differentiate between morphologically very similar species.
http://purl.obolibrary.org/obo/OBI_0002743	molecular label role	http://purl.obolibrary.org/obo/OBI_0000086	reagent role	molecular tracer role	A reagent role inhering in a molecular entity intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay.
http://purl.obolibrary.org/obo/OBI_0002744	molecular label	http://purl.obolibrary.org/obo/OBI_0001879	reagent	molecular tracer	A molecular reagent intended to associate with some molecular target to serve as a proxy for the presence, abundance, or location of this target in a detection of molecular label assay
http://purl.obolibrary.org/obo/OBI_0002786	personal protective device	http://purl.obolibrary.org/obo/OBI_0000968	device	personal protective equipment	A device which is a wearable garment designed to protect the wearer's body from injury or infection.
http://purl.obolibrary.org/obo/OBI_0002787	face mask	http://purl.obolibrary.org/obo/OBI_0002786	personal protective device	face covering	A personal protective device worn over the nose and mouth as a respiratory filter to inhibit the flow of particles.
http://purl.obolibrary.org/obo/OBI_0002788	non-medical mask	http://purl.obolibrary.org/obo/OBI_0002787	face mask	cloth mask	A face mask not manufactured according to medical equipment standards.
http://purl.obolibrary.org/obo/OBI_0002789	medical mask	http://purl.obolibrary.org/obo/OBI_0002787	face mask	surgical mask	A face mask manufactured according to a recognized medical equipment standard.
http://purl.obolibrary.org/obo/OBI_0002790	N95 respirator	http://purl.obolibrary.org/obo/OBI_0002787	face mask	N95 respirator mask	A face mask that meets the U.S. National Institute for Occupational Safety and Health (NIOSH) N95 classification of air filtration, meaning that it filters at least 95% of incoming airborne particles.
http://purl.obolibrary.org/obo/OBI_0002791	face shield	http://purl.obolibrary.org/obo/OBI_0002786	personal protective device	splash shield	A personal protective device used to protect the wearer's entire face (or part of it) from hazards such as flying objects and road debris, chemical splashes, or alternately potentially infectious materials.
http://purl.obolibrary.org/obo/OBI_0002792	patient gown	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item	hospital gown	A personal protective clothing item which is a gown designed for use by a patient to facilitate caregiving by medical staff.
http://purl.obolibrary.org/obo/OBI_0002793	scrubs	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item	scrub clothing item	A personal protective clothing item which is sterilized and which is worn by a health care professional.  It can reference a shirt and pants or dress, and depending on medical protocol, may include a medical cap.
http://purl.obolibrary.org/obo/OBI_0002796	medical gown	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item	hospital gown	A personal protective clothing item which is a gown worn by a medical professional in order to provide a barrier between patient and professional.
http://purl.obolibrary.org/obo/OBI_0002802	laboratory coat	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item	white coat	A personal protective clothing item which is an overcoat worn by medical or laboratory professionals.
http://purl.obolibrary.org/obo/OBI_0002805	transparent droplet barrier	http://purl.obolibrary.org/obo/OBI_0000968	device	transparent partition	A device which is a transparent constructed barrier, usually made out of acrylic (Plexiglass) or polycarbonate plastic, installed in facilities to intercept respiratory droplets, encourage physical distancing requirements.
http://purl.obolibrary.org/obo/OBI_0002806	footwear cover	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item	shoe cover	A personal protective device which is an impermiable material which covers a shoe or boot in order to prevent spread of specific environmental contaminants.
http://purl.obolibrary.org/obo/OBI_0002809	surgical N95 respirator	http://purl.obolibrary.org/obo/OBI_0002790	N95 respirator	surgical N95 respirator	A N95 respirator which has been approved by the FDA as a surgical mask.
http://purl.obolibrary.org/obo/OBI_0002813	medical cap	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item	surgical hat	A personal protective device which is worn on the head that helps prevent transmission of contaminants contained in hair and scalp.
http://purl.obolibrary.org/obo/OBI_0002819	specimen pad	http://purl.obolibrary.org/obo/OBI_0002814	specimen collection device	swab	A sample collection device consisting of a soft flexible, absorbent pad usually made from natural material such as gauze or cotton, used to absorb specimen fluid or particulate matter.
http://purl.obolibrary.org/obo/OBI_0002820	specimen collection swab stick	http://purl.obolibrary.org/obo/OBI_0002814	specimen collection device	sponge-stick	A specimen collection device which is a specimen pad attached to a long handle used to collect specimen material.
http://purl.obolibrary.org/obo/OBI_0002821	cotton swab	http://purl.obolibrary.org/obo/OBI_0000968	device	swab-sampler	A device which is a cotton pad mounted on one or both ends of a stick.
http://purl.obolibrary.org/obo/OBI_0002975	input protein sequence start site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	query protein start site	The position of the first amino acid in a protein sequence being analyzed (input protein sequence).
http://purl.obolibrary.org/obo/OBI_0002976	input protein sequence stop site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	query protein stop site	The position of the last amino acid in a protein sequence being analyzed (input protein sequence).
http://purl.obolibrary.org/obo/OBI_0002977	input gene sequence start site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	query gene start site	The position of the first nucleotide in a gene sequence being analyzed (input gene sequence).
http://purl.obolibrary.org/obo/OBI_0002978	input gene sequence stop site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	query gene stop site	The position of the last nucelotide in a gene sequence being analyzed (input gene sequence).
http://purl.obolibrary.org/obo/OBI_0002979	reference protein sequence start site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	subject protein start site	The position of the first amino acid in a reference protein sequence (sequence being used for comparison).
http://purl.obolibrary.org/obo/OBI_0002980	reference protein sequence stop site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	subject protein stop site	The position of the last amino acid in a reference protein sequence (sequence being used for comparison).
http://purl.obolibrary.org/obo/OBI_0002981	reference gene sequence start site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	subject gene start site	The position of the first nucleotide in a reference gene sequence (sequence being used for comparison).
http://purl.obolibrary.org/obo/OBI_0002982	reference gene sequence stop site	http://purl.obolibrary.org/obo/OBI_0000973	sequence data	subject gene stop site	The position of the last nucelotide in a reference sequence (sequence being used for comparison).
http://purl.obolibrary.org/obo/OBI_0002984	capture Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay	cHi-C	A Hi-C assay in which a selection step is performed on ligated fragments in order to enrich for ligation products containing specific regions of interest.
http://purl.obolibrary.org/obo/OBI_0002985	magnetic resonance imaging assay	http://purl.obolibrary.org/obo/OBI_0000185	imaging assay	MRI	An imaging assay in which nuclear magnetic resonance is used to produce information about the interior structure and composition of an input material entity.
http://purl.obolibrary.org/obo/OBI_0002986	computed tomography imaging assay	http://purl.obolibrary.org/obo/OBI_0000185	imaging assay	CAT scan	An imaging assay that uses a series of X-ray images to produce information about the interior structure and composition of an input material entity.
http://purl.obolibrary.org/obo/OBI_0002987	positron emission tomography imaging assay	http://purl.obolibrary.org/obo/OBI_0000185	imaging assay	positron emission tomography scan	An imaging assay in which positron-emitting radionuclides are used to visualize functional processes of an input material entity.
http://purl.obolibrary.org/obo/OBI_0002990	T cell receptor repertoire sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	bulk TCR assay	A sequencing assay that determines the sequences of DNA or RNA molecules that encode the repertoire of T cell receptors within an input sample.
http://purl.obolibrary.org/obo/OBI_0002991	B cell receptor repertoire sequencing assay	http://purl.obolibrary.org/obo/OBI_0600047	sequencing assay	bulk BCR assay	A sequencing assay that determines the sequence of a DNA or RNA molecules that encode the repertoire of B cell receptors within an input sample.
http://purl.obolibrary.org/obo/OBI_0002128	Illumina Genome Analyzer	http://purl.obolibrary.org/obo/OBI_0400103	DNA sequencer	Illumina Genome Analyzer I	A DNA sequencer manufactured by Solexa as one of its first sequencer lines, launched in 2006, and capable of sequencing 1 gigabase (Gb) of data in a single run.
http://purl.obolibrary.org/obo/OBI_0002129	Illumina HiSeq X Ten	http://purl.obolibrary.org/obo/OBI_0003683	Illumina HiSeq series instrument	HiSeq X Ten	A DNA sequencer that consists of a set of 10 HiSeq X Sequencing Systems.
http://purl.obolibrary.org/obo/OBI_0002132	pulse stable isotope labeling by amino acids in cell culture	http://purl.obolibrary.org/obo/OBI_0000070	assay	pulsed SILAC	An assay that detects differences in protein abundance using samples that have been metabolically labeled in vivo with a stable non-radioactive heavy isotope containing amino acid for a short period of time. After diluting the pulsed cells into growth media without label, high resolution mass spectrometry-based proteomics is used to analyze the time-dependent decay and determine protein stability.
http://purl.obolibrary.org/obo/OBI_0002594	direct interaction identification design	http://purl.obolibrary.org/obo/OBI_0002590	molecular interaction identification design	molecular binding identification design	A molecular interaction identification design that investigates the influence of molecules, which are in direct contact, on one another.
http://purl.obolibrary.org/obo/OBI_0002597	chromosome conformation capture sequencing assay	http://purl.obolibrary.org/obo/OBI_0002458	chromosome conformation capture-on-chip assay	3C-seq assay	A chromosome conformation capture-on-chip assay quantitates the products with multiplexed high-throughput sequencing.
http://purl.obolibrary.org/obo/OBI_0002612	fecal swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen	stool swab specimen	A specimen that is collected with a swab from the surface of a feces.
http://purl.obolibrary.org/obo/OBI_1200000	FFPE specimen	http://purl.obolibrary.org/obo/OBI_0000950	paraffin specimen	formalin-fixed paraffin-embeded specimen	A specimen that has been fixed in formalin and embedded in paraffin.
http://purl.obolibrary.org/obo/OBI_0002988	specimen collection duration	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum	specimen collection duration	A time measurement datum that is the count of collection cycles over which a specimen collection process occurs.
http://purl.obolibrary.org/obo/OBI_0003707	mortar and pestle device	http://purl.obolibrary.org/obo/OBI_0000968	device	mortar and pestle	A device which is a set of two tools used to crush or grind material into smaller particles. A mortar is used to contain the material, and a pestle is a handheld blunt object used to apply force to the material.
http://purl.obolibrary.org/obo/OBI_0002778	tracheal aspirate specimen	http://purl.obolibrary.org/obo/OBI_0002781	lower respiratory tract aspirate specimen	tracheal wash specimen	A specimen that is collected with a suctioning tube from the trachea.
http://purl.obolibrary.org/obo/OBI_0002780	nasal aspirate specimen	http://purl.obolibrary.org/obo/OBI_2000006	upper respiratory tract specimen	nasopharyngeal aspirate	A specimen that is collected with a suctioning tube from the nasal cavity.
http://purl.obolibrary.org/obo/OBI_0002781	lower respiratory tract aspirate specimen	http://purl.obolibrary.org/obo/OBI_0002783	lower respiratory tract specimen	lower respiratory tract wash specimen	A specimen that is collected with a suctioning tube from the lower respiratory tract.
http://purl.obolibrary.org/obo/OBI_0002785	aspiration specimen collection	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process	aspiration procedure	Procedure using suction, usually with a thin needle and syringe, to remove bodily fluid or tissue.
http://purl.obolibrary.org/obo/OBI_0002898	cluster study group role	http://purl.obolibrary.org/obo/OBI_0000174	study group role	cluster study arm	A study group role that is the result of the allocation of a cluster of study-defined groupings of people in a clinical trial to receive a specific intervention/treatment, or no intervention, according to the trial's protocol.
http://purl.obolibrary.org/obo/OBI_0002899	compound study group role	http://purl.obolibrary.org/obo/OBI_0000174	study group role	compound study arm	A study group role that is the result of the allocation of a compound of geographically-proximate households with a shared component in a clinical trial to receive a specific intervention/treatment, or no intervention, according to the trial's protocol.
http://purl.obolibrary.org/obo/OBI_0002900	ultraviolet light source	http://purl.obolibrary.org/obo/OBI_0400065	light source	UV light source	A light source that provides ultraviolet (UV) light for use in a distant area using a delivery system.
http://purl.obolibrary.org/obo/OBI_0002904	adult arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0002919	live arthropod specimen collection process	collection of adults	A live arthropod specimen collection process in which the arthropods are in the adult stage.
http://purl.obolibrary.org/obo/OBI_0002905	animal-biting arthropod specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002912	arthropod specimen collection by aspiration	animal biting catch	An arthropod specimen collection by aspiration that occurs while the arthropod is biting an animal.
http://purl.obolibrary.org/obo/OBI_0002906	animal-biting outdoor arthropod specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002905	animal-biting arthropod specimen collection by aspiration	animal biting catch - outdoors	An animal-biting arthropod specimen collection by aspiration that occurs outside a building.
http://purl.obolibrary.org/obo/OBI_0002907	aquatic arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0002913	arthropod specimen collection process	aquatic environment catch	An arthropod specimen collection process that has the objective of collecting mosquitoes from an aquatic environment.
http://purl.obolibrary.org/obo/OBI_0002908	arthropod resting in animal house specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002912	arthropod specimen collection by aspiration	animal shed resting catch	An arthropod specimen collection by aspiration that catches specimens resting inside an animal house.
http://purl.obolibrary.org/obo/OBI_0002909	arthropod resting outdoors on artificial support specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002911	arthropod resting outdoors specimen collection by aspiration	outdoors shelter catch - artificial	An arthropod resting outdoors specimen collection by aspiration that occurs while the arthropod rests on a processed material such as a wall or furniture.
http://purl.obolibrary.org/obo/OBI_0002910	arthropod resting outdoors on natural support specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002911	arthropod resting outdoors specimen collection by aspiration	outdoors shelter catch - natural	An arthropod resting outdoors specimen collection by aspiration that occurs while the arthropod rests on an unprocessed material such as a plant.
http://purl.obolibrary.org/obo/OBI_0002911	arthropod resting outdoors specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002905	animal-biting arthropod specimen collection by aspiration	outdoors shelter catch	An animal-biting arthropod specimen collection by aspiration that occurs while the arthropod is resting outside a building during a period of inactivity.
http://purl.obolibrary.org/obo/OBI_0002912	arthropod specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002904	adult arthropod specimen collection process	catch by aspiration	A live arthropod specimen collection process that involves the use of an aspirator, a device which draws an arthropod by suction into a container.
http://purl.obolibrary.org/obo/OBI_0002913	arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process	field population catch	A specimen collection process that has the objective of collecting arthropods as specimens.
http://purl.obolibrary.org/obo/OBI_0002914	human-biting arthropod specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002912	arthropod specimen collection by aspiration	man biting catch	An arthropod specimen collection by aspiration that occurs while the arthropod is biting a human.
http://purl.obolibrary.org/obo/OBI_0002915	human-biting indoor arthropod specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002914	human-biting arthropod specimen collection by aspiration	man biting catch - indoors	An arthropod specimen collection by aspiration that occurs while the arthropod is biting a human inside a building.
http://purl.obolibrary.org/obo/OBI_0002916	human-biting outdoor arthropod specimen collection by aspiration	http://purl.obolibrary.org/obo/OBI_0002914	human-biting arthropod specimen collection by aspiration	man biting catch - outdoors	An arthropod specimen collection by aspiration designed to catch specimens that are in the process of biting a human outside a building.
http://purl.obolibrary.org/obo/OBI_0002917	knockdown arthropod specimen collection by pyrethrum spray	http://purl.obolibrary.org/obo/OBI_0002918	knockdown arthropod specimen collection process	pyrethrum spray catch	A knockdown arthropod specimen collection process in which the pesticide is pyrethrum.
http://purl.obolibrary.org/obo/OBI_0002918	knockdown arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0002919	live arthropod specimen collection process	knockdown collection	An arthropod specimen collection process that involves exposing arthropods to pesticide, then collecting them once they become dead or immobilized.
http://purl.obolibrary.org/obo/OBI_0002919	live arthropod specimen collection process	http://purl.obolibrary.org/obo/OBI_0002913	arthropod specimen collection process	catch of live specimens	An arthropod specimen collection process meant to collect live specimens.
http://purl.obolibrary.org/obo/OBI_0002926	Centers for Disease Control and Prevention light trap	http://purl.obolibrary.org/obo/OBI_0002930	light trap	CDC light trap	A light trap that is designed similarly to the New Jersey trap—in that it uses motorized suction and light attractant—and is powered by a six-volt battery.
http://purl.obolibrary.org/obo/OBI_0002927	dipper for arthropod immatures	http://purl.obolibrary.org/obo/OBI_0000968	device	dipper for immatures	A device that is designed for the collection of arthropod larvae or pupae from water and has the shape of a ladle or a pan.
http://purl.obolibrary.org/obo/OBI_0002928	encephalitis virus surveillance trap	http://purl.obolibrary.org/obo/OBI_0002930	light trap	EVS trap	A light trap that uses carbon dioxide as attractant. The trap consists of a container of dry ice with holes in the bottom to allow the carbon dioxide to flow downward into a separate container, in which a motorized fan creates suction to collect arthropods.
http://purl.obolibrary.org/obo/OBI_0002931	light trap for indoor use	http://purl.obolibrary.org/obo/OBI_0002930	light trap	indoor light trap	A light trap designed to be placed inside a building.
http://purl.obolibrary.org/obo/OBI_0002932	light trap for outdoor use	http://purl.obolibrary.org/obo/OBI_0002930	light trap	outdoor light trap	A light trap designed to be placed outside a building.
http://purl.obolibrary.org/obo/OBI_0002935	New Jersey light trap	http://purl.obolibrary.org/obo/OBI_0002930	light trap	New Jersey trap	A light trap that is designed to use motorized suction to trap arthropods in a collection bag once they approach the light attractant.
http://purl.obolibrary.org/obo/OBI_0002936	Onderstepoort Veterinary Institute light-suction trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap	OVI light-suction trap	A light trap that is designed to use motorized suction to trap arthropods in a collection bag once they approach the attractant. The light is supplied by an 8 watt tube, and the fan providing the suction has an 11-centimeter diameter.
http://purl.obolibrary.org/obo/OBI_0002937	outlet window trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap	outlet window trap	An arthropod trap that is positioned adjacent to a window of a building and is designed to collect arthropods flying out of the building.
http://purl.obolibrary.org/obo/OBI_0002938	ovitrap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap	oviposition trap	An arthropod trap that consists of a container holding a mesh layer above water and is designed to trap arthropods hatched from eggs dropped over the water by gravid females.
http://purl.obolibrary.org/obo/OBI_0002940	resting box trap	http://purl.obolibrary.org/obo/OBI_0002939	resting arthropod trap	resting box catch	An arthropod trap that consists of a box that is open on one end. The placement of the box and modifications to it are done in such a way that it becomes attractive to an arthropod as a place to rest during a period of inactivity.
http://purl.obolibrary.org/obo/OBI_0002941	resting bucket	http://purl.obolibrary.org/obo/OBI_0002939	resting arthropod trap	resting bucket catch	An arthropod trap that consists of a bucket, which is lined with fabric and placed on its side, and a wet cloth inside the bucket. The placement of the box and modifications to it are done in such a way that it becomes attractive to an arthropod as a place to rest during a period of inactivity (not actively seeking a host).
http://purl.obolibrary.org/obo/OBI_0002942	Shannon trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap	shannon trap catch	An arthropod trap that is made of cloth and netting and is designed to be suspended from above (e.g. from a tree). It is also designed so that the arthropod enters the trap from beneath, being attracted to some bait, and is prevented from escaping upward by the suspended cloth, which allows them to be collected from the upper interior of the trap.
http://purl.obolibrary.org/obo/OBI_0002943	sticky resting bucket	http://purl.obolibrary.org/obo/OBI_0002939	resting arthropod trap	sticky resting bucket catch	An arthropod trap that consists of a bucket, which is lined with adhesive and placed on its side, and a wet cloth inside the bucket. The placement of the box and modifications to it are done in such a way that it becomes attractive to an arthropod as a place to rest during a period of inactivity. The trap is designed for arthropods to become caught in the adhesive so that they can be collected.
http://purl.obolibrary.org/obo/OBI_0002944	sticky trap	http://purl.obolibrary.org/obo/OBI_0002939	resting arthropod trap	sticky trap catch	An arthropod trap that is designed to capture arthropods resting on a surface by coating the surface with adhesive.
http://purl.obolibrary.org/obo/OBI_0002993	prevalence of blood meal specimens from a host organism	http://purl.obolibrary.org/obo/IAO_0000027	data item	host blood index	A data item that is the frequency of blood whose source is from a specified host organism in collected blood meal specimens.
http://purl.obolibrary.org/obo/OBI_0002994	presence of blood from host organism in blood meal specimen	http://purl.obolibrary.org/obo/IAO_0000027	data item	presence of blood meal host organism	A data item that indicates whether blood in a blood meal specimen came from a specified host organism.
http://purl.obolibrary.org/obo/OBI_0002995	blood meal source organism	http://purl.obolibrary.org/obo/OBI_0100026	organism	blood meal host organism	An organism that is the source of a blood meal.
http://purl.obolibrary.org/obo/OBI_0003663	Illumina NovaSeq X	http://purl.obolibrary.org/obo/OBI_0003685	Illumina NovaSeq series instrument	NovaSeq X System	A DNA sequencer with three flow cell types manufactured by Illumina. The NovaSeq X provides an output of up to 8 Tb (26-52 billion reads per run). The sequencer utilizes XLEAP-SBS chemistry, an advanced version of Illumina's sequencing by synthesis (SBS) technology, which enables faster and more accurate sequencing.
http://purl.obolibrary.org/obo/PBPKO_00435	lactational pbpk	http://purl.obolibrary.org/obo/PBPKO_00003	physiologically based pharmacokinetic model		A physiologically based pharmacokinetic model specifically built to predict compound concentrations during lactation, including transfer into milk.
http://purl.obolibrary.org/obo/PBPKO_00448	alveolar air compartment	http://purl.obolibrary.org/obo/PBPKO_00559	lung compartment		A lung compartment specifically representing the air within the alveoli.
http://purl.obolibrary.org/obo/PBPKO_00455	viable unexposed skin compartment	http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment		A skin compartment representing the viable layers of skin not directly exposed to the applied compound.
http://purl.obolibrary.org/obo/PBPKO_00456	viable exposed skin compartment	http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment		A skin compartment representing the viable layers of skin directly exposed to the applied compound.
http://purl.obolibrary.org/obo/PBPKO_00457	skin unexposed stratum corneum	http://purl.obolibrary.org/obo/PBPKO_00493	stratum corneum compartment		A stratum corneum compartment representing the portion not directly exposed to the applied compound.
http://purl.obolibrary.org/obo/PBPKO_00493	stratum corneum compartment	http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment		A skin compartment representing the stratum corneum layer.
http://purl.obolibrary.org/obo/PBPKO_00458	skin exposed stratum corneum compartment	http://purl.obolibrary.org/obo/PBPKO_00493	stratum corneum compartment		A stratum corneum compartment representing the portion directly exposed to the applied compound.
http://purl.obolibrary.org/obo/PBPKO_00461	anal canal compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the anal canal.
http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment	http://purl.obolibrary.org/obo/PBPKO_00553	digestive system compartment		A digestive system compartment representing the large intestine.
http://purl.obolibrary.org/obo/PBPKO_00462	appendix compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the appendix.
http://purl.obolibrary.org/obo/PBPKO_00463	ascending colon compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the ascending colon.
http://purl.obolibrary.org/obo/PBPKO_00467	cecum compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the cecum.
http://purl.obolibrary.org/obo/PBPKO_00468	descending colon compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the descending colon.
http://purl.obolibrary.org/obo/PBPKO_00469	dermis compartment	http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment		A skin compartment representing the dermis layer.
http://purl.obolibrary.org/obo/PBPKO_00471	duodenum compartment	http://purl.obolibrary.org/obo/PBPKO_00472	small intestine compartment		A small intestine compartment representing the duodenum.
http://purl.obolibrary.org/obo/PBPKO_00472	small intestine compartment	http://purl.obolibrary.org/obo/PBPKO_00553	digestive system compartment		A digestive system compartment representing the small intestine.
http://purl.obolibrary.org/obo/PBPKO_00475	epidermis compartment	http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment		A skin compartment representing the epidermis layer.
http://purl.obolibrary.org/obo/PBPKO_00476	gall bladder compartment	http://purl.obolibrary.org/obo/PBPKO_00553	digestive system compartment		A digestive system compartment representing the gall bladder.
http://purl.obolibrary.org/obo/PBPKO_00477	gut compartment	http://purl.obolibrary.org/obo/PBPKO_00553	digestive system compartment		A digestive system compartment representing the gut (general term, often synonymous with intestine or GI tract).
http://purl.obolibrary.org/obo/PBPKO_00478	gut lumen compartment	http://purl.obolibrary.org/obo/PBPKO_00553	digestive system compartment		A digestive system compartment representing the lumen (opening) within the gut.
http://purl.obolibrary.org/obo/PBPKO_00481	ileum compartment	http://purl.obolibrary.org/obo/PBPKO_00472	small intestine compartment		A small intestine compartment representing the ileum.
http://purl.obolibrary.org/obo/PBPKO_00482	jejunum compartment	http://purl.obolibrary.org/obo/PBPKO_00472	small intestine compartment		A small intestine compartment representing the jejunum.
http://purl.obolibrary.org/obo/PBPKO_00487	placental barrier compartment	http://purl.obolibrary.org/obo/PBPKO_00495	barrier compartment		A barrier compartment representing the placental barrier separating maternal and fetal circulation.
http://purl.obolibrary.org/obo/PBPKO_00489	rectum compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the rectum.
http://purl.obolibrary.org/obo/PBPKO_00491	sigmoid colon compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the sigmoid colon.
http://purl.obolibrary.org/obo/PBPKO_00494	transverse colon compartment	http://purl.obolibrary.org/obo/PBPKO_00474	large intestine compartment		A large intestine compartment representing the transverse colon.
http://purl.obolibrary.org/obo/PBPKO_00551	PBPK model simulation time	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter representing the time duration over which the model simulation runs.
http://purl.obolibrary.org/obo/PBPKO_00566	stomach compartment	http://purl.obolibrary.org/obo/PBPKO_00553	digestive system compartment		A digestive system compartment representing the stomach.
http://purl.obolibrary.org/obo/PBPKO_00617	hippocampus compartment	http://purl.obolibrary.org/obo/PBPKO_00466	brain compartment		A part of brain compartment representing the hippocampus region of the brain
http://purl.obolibrary.org/obo/PBPKO_00618	cerebrum compartment	http://purl.obolibrary.org/obo/PBPKO_00466	brain compartment		A part of brain compartment representing the cerebrum region of the brain
http://purl.obolibrary.org/obo/PBPKO_00619	cerebellum compartment	http://purl.obolibrary.org/obo/PBPKO_00466	brain compartment		A part of brain compartment representing the cerebellum region of the brain
http://purl.obolibrary.org/obo/PBPKO_00620	frontal cortex compartment	http://purl.obolibrary.org/obo/PBPKO_00466	brain compartment		A part of brain compartment representing the frontal cortex region of the brain
http://purl.obolibrary.org/obo/PBPKO_00621	cerebrospinal fluid compartment	http://purl.obolibrary.org/obo/PBPKO_00466	brain compartment		A part of brain compartment representing the cerebrospinal fluid region of the brain
http://purl.obolibrary.org/obo/PBPKO_00625	exposed skin compartment	http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment		A skin compartment representing the exposed part of the skin to the chemical via dermal contact.
http://purl.obolibrary.org/obo/PBPKO_00626	unexposed skin compartment	http://purl.obolibrary.org/obo/PBPKO_00470	skin compartment		A skin compartment representing the unexposed part of the skin to the chemical such as regions covered by clothing or occluded areas like the inner arms.
http://purl.obolibrary.org/obo/PBPKO_00634	red blood cell compartment	http://purl.obolibrary.org/obo/PBPKO_00446	compartment		A compartment representing the red blood cells of the body.
http://purl.obolibrary.org/obo/PBPKO_00635	skin thickness	http://purl.obolibrary.org/obo/PBPKO_00006	physiological parameter		A physiological parameter representing the thickness of the skin compartment
http://purl.obolibrary.org/obo/PBPKO_00646	diffusion rate	http://purl.obolibrary.org/obo/PBPKO_00139	biochemical parameter		A biochemical parameter representing the diffusion rate of the chemical
http://purl.obolibrary.org/obo/PBPKO_00647	diffusion rate skin	http://purl.obolibrary.org/obo/PBPKO_00646	diffusion rate		A diffusion rate parameter representing diffusion rate of the chemical across the skin
http://purl.obolibrary.org/obo/PBPKO_00649	miscellaneous parameter	http://purl.obolibrary.org/obo/PBPKO_00002	parameter		A parameter being used in the model but does not belong to specific parameter subclass
http://purl.obolibrary.org/obo/PBPKO_00650	Michaelis	http://purl.obolibrary.org/obo/PBPKO_00649	miscellaneous parameter		A flag indicating for Michaelis-Menten or linear metabolism equation being used in the model
http://purl.obolibrary.org/obo/HP_0012824	Severity	http://purl.obolibrary.org/obo/BFO_0000019	quality		The intensity or degree of a manifestation.
http://purl.obolibrary.org/obo/IDO_0000450	pathogenic disposition	http://purl.obolibrary.org/obo/BFO_0000016	disposition		A disposition to initiate processes that result in a disorder.
http://purl.obolibrary.org/obo/IDO_0000528	pathogen	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity with a pathogenic disposition.
http://purl.obolibrary.org/obo/IDO_0000562	antibacterial	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A material entity bearing an antibacterial disposition.
http://purl.obolibrary.org/obo/PR_000050331	lactate dehydrogenase complex	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A protein-containing complex that is composed of four subunits of L-lactate dehydrogenase, cytoplasmic.
http://purl.obolibrary.org/obo/PR_000050343	alkaline phosphatase (human)	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of any of the following alkaline phosphatase genes in human: ALPG (encoding the germinal form; GCAP), ALPP (encoding the placental form; PLAP), ALPI (encoding the intestinal form; IAP), and ALPL (encoding the tissue non-specific form; TNAP).
http://purl.obolibrary.org/obo/PR_000050353	aspartate aminotransferase (human)	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of any of the following genes in human: GOT1/GOT2.
http://purl.obolibrary.org/obo/OBI_0003336	functional magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003334	reconstructed magnetic resonance image data set		An magnetic resonance image data set collected as a 4D time series representing changes in brain metabolism (i.e. BOLD), typically used as a proxy for brain activity.
http://purl.obolibrary.org/obo/OBA_2060180	limb coordination efficacy	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The process efficacy of a limb coordination.
http://purl.obolibrary.org/obo/OBA_2060181	upper limb coordination efficacy	http://purl.obolibrary.org/obo/OBA_2060180	limb coordination efficacy		The process efficacy of a upper limb coordination.
http://purl.obolibrary.org/obo/OBA_2060182	lower limb coordination efficacy	http://purl.obolibrary.org/obo/OBA_2060180	limb coordination efficacy		The process efficacy of a lower limb coordination.
http://purl.obolibrary.org/obo/OBA_2060184	whole organism stability	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The stability of a multicellular organism.
http://purl.obolibrary.org/obo/OBA_2060185	facial muscle performance	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The functionality of a facial muscle.
http://purl.obolibrary.org/obo/OBA_2060186	peripheral nervous system function	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The functionality of a peripheral nervous system.
http://purl.obolibrary.org/obo/OBA_2060187	knee joint functionality	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The functionality of a knee joint.
http://purl.obolibrary.org/obo/OBA_2060188	ankle joint functionality	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The functionality of a ankle joint.
http://purl.obolibrary.org/obo/OBA_2060189	tendon of biceps brachii functionality	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The functionality of a tendon of biceps brachii.
http://purl.obolibrary.org/obo/OBA_2060190	brachioradialis functionality	http://purl.obolibrary.org/obo/OBA_0000001	biological attribute		The functionality of a brachioradialis.
http://purl.obolibrary.org/obo/OBI_0003718	pulse rate assay	http://purl.obolibrary.org/obo/OBI_0003715	vital sign assay		A vital sign assay that measures the heart beat rate of an organism.
http://purl.obolibrary.org/obo/ENVO_01000739	habitat	http://purl.obolibrary.org/obo/ENVO_01000254	environmental system		An environmental system which can sustain and allow the growth of an ecological population.
http://purl.obolibrary.org/obo/OGMS_0000073	diagnosis	http://purl.obolibrary.org/obo/IAO_0000027	data item		The representation of a conclusion of a diagnostic process.
http://purl.obolibrary.org/obo/OBI_0002444	measurand role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role borne by a material entity and realized in an assay which achieves the objective to measure the magnitude/concentration/amount of the measurand in the entity bearing evaluant role.
http://purl.obolibrary.org/obo/OBI_0002445	transcription start site mapping by primer extension assay	http://purl.obolibrary.org/obo/OBI_0000424	transcription profiling assay		A transcription profiling assay in which the transcription start site for a gene is determined by identifying the 5' end of mRNA. A radio-labeled primer is annealed to a complementary mRNA sequence near the 3' end, then cDNA is synthesized until the 5' end is reached.
http://purl.obolibrary.org/obo/OBI_0002446	proteomic profiling design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design in which proteins in a sample are detected, quantified or otherwise analysed.
http://purl.obolibrary.org/obo/OBI_0002449	footprinting assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0001703	assay measuring qualitative binding of a B cell epitope:antibody complex		A footprinting assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0002450	hydroxyl-radical footprinting assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_0002442	hydroxyl-radical footprinting assay		A hydroxyl-radical footprinting assay that detects the binding of an antigen with an antibody.
http://purl.obolibrary.org/obo/OBI_0002451	ELISA measuring epitope specific interferon-alpha production by T cells	http://purl.obolibrary.org/obo/OBI_0002452	assay measuring epitope specific interferon-alpha production by T cells		An enzyme-linked immunosorbent assay that detects interferon-alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0002452	assay measuring epitope specific interferon-alpha production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects interferon-alpha production by T cells.
http://purl.obolibrary.org/obo/OBI_0002453	health status inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more clinically significant bodily components, dispositions, and/or bodily processes of an entity that are inferred from relevant clinical findings or self-reported, which, if met, makes the entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002454	clinically relevant lifestyle inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more clinically relevant planned processes that a human being actively participates in , which, if met, makes the human being suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002455	clinically relevant exposure inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more clinically relevant histories of exposure of an entity, which, if met, makes the entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002456	gravidity inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states one or more gravidity statuses of an organism, which, if met, makes the entity suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002590	molecular interaction identification design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that investigates the features of interaction between molecules.
http://purl.obolibrary.org/obo/OBI_0002589	unsupervised machine learning	http://purl.obolibrary.org/obo/OBI_0002587	machine learning		A machine learning process that infers a function describing the structure of "unlabeled" data (i.e. data that has not been classified or categorized).
http://purl.obolibrary.org/obo/OBI_0002492	case role in case-control study	http://purl.obolibrary.org/obo/OBI_0000097	participant under investigation role		A role that is borne by a case-control study design participant under investigation that is associated with the outcome mentioned in the study design.
http://purl.obolibrary.org/obo/OBI_0002493	control role in case-control study	http://purl.obolibrary.org/obo/OBI_0000097	participant under investigation role		A role that is borne by a case-control study design participant under investigation that is not associated with the outcome mentioned in the study design.
http://purl.obolibrary.org/obo/OBI_0002619	site-directed mutagenesis	http://purl.obolibrary.org/obo/OBI_0001154	induced mutagenesis		An induced mutation in which a specific base change is programmed into the sequence of a synthetic primer.
http://purl.obolibrary.org/obo/OBI_0002620	random mutagenesis	http://purl.obolibrary.org/obo/OBI_0001154	induced mutagenesis		An induced mutation that produces a random mutation, either by introducing the organism to mutagens, or through a process such as error-prone PCR.
http://purl.obolibrary.org/obo/OBI_0002622	in vitro transcription reconstitution assay	http://purl.obolibrary.org/obo/OBI_0002621	reconstitution assay		A reconstitution assay in which RNA synthesis is investigated using RNA polymerase II transcription systems replicated in vitro from their base components.
http://purl.obolibrary.org/obo/OBI_0002624	case-control study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that entails the creation of two types of roles, such that each participant under investigation bears one or the other. What distinguishes the two types of roles is an 'outcome', which is associated with participants that have the case role but not associated with participants that have the control role. A case-control study examines the hypothesis that the presence of the outcome in case participants is associated with an 'exposure' that is not associated with control participants.
http://purl.obolibrary.org/obo/OBI_0002627	ribosomal RNA-depleted RNA extract	http://purl.obolibrary.org/obo/OBI_0000880	RNA extract		An extract of RNA which is produced through rRNA (ribosomal RNA) depletion (the removal of highly abundant rRNA species).
http://purl.obolibrary.org/obo/PR_000050469	hemoglobin A1c	http://purl.obolibrary.org/obo/GO_0032991	protein-containing complex		A hemoglobin complex that is composed of at least one beta-N-1-deoxy fructosyl hemoglobin subunit, in which the glycan is attached to the N-terminal valine (after initiator methionine removal) of one or both beta subunits.
http://purl.obolibrary.org/obo/OBI_0002946	fluorescence imaging-based apoptosis assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures associated with molecular processes of apoptosis.
http://purl.obolibrary.org/obo/OBI_0002948	fluorescence imaging-based cell cycle state assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures associated with particular cell cycle states.
http://purl.obolibrary.org/obo/OBI_0002949	fluorescence imaging-based cell viability assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures associated with cell viability.
http://purl.obolibrary.org/obo/OBI_0002950	fluorescence imaging-based drug synergy assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures to determine if drugs applied to cells in combination have a greater effect together than the sum of their separate effects.
http://purl.obolibrary.org/obo/OBI_0002951	fluorescence imaging-based cell morphology assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A type of cytometry assay in which fluorescent dyes are used to label and detect proteins or structures in order to determine cell morphology.
http://purl.obolibrary.org/obo/OBI_0002952	fluorescence imaging multiplex cytological profiling	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A type of cytometry assay in which fluorescent dyes are used to stain seven major cellular components followed by automatic image capture and analysis which extracts shape, texture, and intensity parameters.
http://purl.obolibrary.org/obo/OBI_0002953	protein state assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		A type of assay that measures the quantity and/or identity of proteins in their modficied and unmodified states where modifications include phosphorylation, methylation, acetylation, etc.
http://purl.obolibrary.org/obo/OBI_0002954	fluorescence imaging-based protein phosphorylation state assay	http://purl.obolibrary.org/obo/OBI_0002953	protein state assay		A type of protein state assay that employs high-throughput microscopy to measure levels of proteins in different phosphorylation states.
http://purl.obolibrary.org/obo/OBI_0002955	mass spectrometry-based protein state assay	http://purl.obolibrary.org/obo/OBI_0002953	protein state assay		A type of protein state assay that employs mass spectrometry to measure levels of proteins in different phosphorylation states.
http://purl.obolibrary.org/obo/OBI_0002959	tandem mass tag mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0003540	tandem mass spectrometry assay		A type of tandem mass spectrometry where isotopomer labels are employed for accurate quantification and identification of specific proteins.
http://purl.obolibrary.org/obo/OBI_0002960	fluorescence imaging-based reporter gene assay	http://purl.obolibrary.org/obo/OBI_0002082	reporter gene assay		A type of reporter gene assay that employs fluorescence imaging to detect a reporter gene's expression.
http://purl.obolibrary.org/obo/OBI_0002962	kinase inhibitor assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		A type of assay that identifies compounds that inhibit the activity of kinases.
http://purl.obolibrary.org/obo/OBI_0002963	KINOMEscan assay	http://purl.obolibrary.org/obo/OBI_0002962	kinase inhibitor assay		A type of proprietary kinase inhibitor assay that and employs a panel of kinases against which one can test compounds for their selectivity and potency in interactions with kinases, without the need to add ATP to the reactions.
http://purl.obolibrary.org/obo/OBI_0002964	KiNativ assay	http://purl.obolibrary.org/obo/OBI_0002962	kinase inhibitor assay		A type of proprietary in situ kinase inhibitor assay that employs biotinylated acyl phosphates of ATP and ADP.
http://purl.obolibrary.org/obo/OBI_0002967	microwestern meso-scale quantitative western blot assay	http://purl.obolibrary.org/obo/OBI_0000854	western blot assay		A western blot assay that provides a high-throughput, sensitive, and quantitative measurement of proteins from numerous samples via an array of small western blots on a single sheet of nitrocellulose.
http://purl.obolibrary.org/obo/OBI_0002969	cyclic immunofluoroescence assay	http://purl.obolibrary.org/obo/OBI_0002119	microscopy assay		A type of microscopy assay resulting in highly multiplexed immunofluorescence imaging through sequential rounds of imaging followed by fluorophore inactivation.
http://purl.obolibrary.org/obo/OBI_0002970	multiplex bead-based protein state immunoassay	http://purl.obolibrary.org/obo/OBI_0002953	protein state assay		A type of protein state assay in which antibodies attached to different colored beads and fluorescent reporter dye labels are used in a multiplexed mixture to assay for proteins in specific states.
http://purl.obolibrary.org/obo/OBI_0003029	barcode target locus role	http://purl.obolibrary.org/obo/OBI_0000067	evaluant role		An evaluant role that is realized in a taxonomic diversity assessment by targeted gene survey involving sequencing a small defined region of genome amplified by PCR.
http://purl.obolibrary.org/obo/OBI_0003032	genotyping by PCR assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay		A genotyping assay that uses polymerase chain reaction.
http://purl.obolibrary.org/obo/OBI_0003035	coma severity assay	http://purl.obolibrary.org/obo/OBI_0002441	physical examination of an organism		A physical examination of an organism that has the objective to determine the severity of coma in a patient.
http://purl.obolibrary.org/obo/OBI_0003036	Plasmodium gametocyte detection assay	http://purl.obolibrary.org/obo/OBI_0003038	parasite detection assay		An assay that detects Plasmodium gametocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003038	parasite detection assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An assay that detects parasite in a specimen.
http://purl.obolibrary.org/obo/OBI_0003040	blood assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has a blood specimen as evaulant.
http://purl.obolibrary.org/obo/OBI_0003041	falcivax rapid diagnostic test	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A parasite detection assay that can quickly establish the diagnosis of P. falciparum or P. vivax malaria infection by detecting the antigens in a person's blood.
http://purl.obolibrary.org/obo/OBI_0003042	optimal-IT rapid diagnostic test	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A parasite detection assay that is rapid, sensitive, and able to differentiate between P. falciparum and other malaria parasites.
http://purl.obolibrary.org/obo/OBI_0003043	urine assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that has a urine specimen as evaluant.
http://purl.obolibrary.org/obo/OBI_0003044	parasite species identification by PCR assay	http://purl.obolibrary.org/obo/OBI_0003045	parasite detection by PCR assay		A parasite detection by PCR assay that identifies the species of parasite.
http://purl.obolibrary.org/obo/OBI_0003045	parasite detection by PCR assay	http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay		A parasite detection assay that uses PCR.
http://purl.obolibrary.org/obo/OBI_0003046	free-standing window trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that consists of a transparent window placed in a box that holds a liquid solution deadly to arthropods. This trap is designed to stop an arthropod in flight, causing it to fall into the liquid and die.
http://purl.obolibrary.org/obo/OBI_0003049	hand-held sweep net	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that consists of a network of mesh and is designed to capture adult arthropods.
http://purl.obolibrary.org/obo/OBI_0003056	proportion mapped reads	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		A sequence datum that is the specified output of a read mapping and is the ratio of the count of mapped reads to the total count of reads.
http://purl.obolibrary.org/obo/OBI_0003057	antibiotic administration process	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		Administering substance in vivo where an antibiotic substance is administered to a living organism.
http://purl.obolibrary.org/obo/OBI_0003063	insecticide resistance datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is about resistance to an insecticide.
http://purl.obolibrary.org/obo/OBI_0003064	organism detection datum	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is the specified output of an organism detection assay.
http://purl.obolibrary.org/obo/OBI_0003066	easting coordinate measurement datum	http://purl.obolibrary.org/obo/IAO_0000401	one dimensional cartesian spatial coordinate datum		A one dimensional Cartesian spatial coordinate datum that is the eastward component of a distance from a point on a map projection.
http://purl.obolibrary.org/obo/OBI_0003067	northing coordinate measurement datum	http://purl.obolibrary.org/obo/IAO_0000401	one dimensional cartesian spatial coordinate datum		A one dimensional Cartesian spatial coordinate datum that is the northward component of a distance from a point on a map projection.
http://purl.obolibrary.org/obo/OBI_0003068	clinical study center	http://purl.obolibrary.org/obo/OBI_0000245	organization		Organization that undertakes a clinical study at some point in time.
http://purl.obolibrary.org/obo/OBI_0003069	sequencing protocol	http://purl.obolibrary.org/obo/OBI_0000272	protocol		A protocol that, when concretized, is realized in an assay that uses chemical or biological means to infer the sequence of a biomaterial.
http://purl.obolibrary.org/obo/OBI_0003070	specimen collection protocol	http://purl.obolibrary.org/obo/OBI_0000272	protocol		A protocol that specifies processes to fulfill a specimen collection objective.
http://purl.obolibrary.org/obo/OBI_0003071	participant identifier	http://purl.obolibrary.org/obo/IAO_0000028	symbol		A symbol that denotes a participant under investigation.
http://purl.obolibrary.org/obo/OBI_0003075	age since birth at time of enrollment	http://purl.obolibrary.org/obo/OBI_0001169	age since birth measurement datum		An age since birth measurement datum at the time of subject enrollment.
http://purl.obolibrary.org/obo/OBI_0003076	age since birth at time of visit	http://purl.obolibrary.org/obo/OBI_0001169	age since birth measurement datum		An age since birth measurement datum at the time of a clinical visit.
http://purl.obolibrary.org/obo/OBI_0003080	organismal body temperature measurement assay	http://purl.obolibrary.org/obo/OBI_0002140	temperature measurement assay		An assay that detects body temperature of an organism.
http://purl.obolibrary.org/obo/OBI_0003081	extraction date	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum		A time measurement datum that specifies when some material was extracted from an input material.
http://purl.obolibrary.org/obo/OBI_0003082	extraction duration time	http://purl.obolibrary.org/obo/IAO_0000416	time measurement datum		A time measurement datum that is the result of measuring the duration of an extraction process.
http://purl.obolibrary.org/obo/OBI_0003083	specimen collection time post disease onset	http://purl.obolibrary.org/obo/OBI_0001619	specimen collection time measurement datum		A specimen collection time measurement datum that is the measure of a time when specimens are collected after the onset of disease in a host.
http://purl.obolibrary.org/obo/OBI_0003084	specimen collection time post infection	http://purl.obolibrary.org/obo/OBI_0001619	specimen collection time measurement datum		A specimen collection time measurement datum that is the measure of a time when specimens are collected after an infection starts.
http://purl.obolibrary.org/obo/OBI_0003086	laboratory-based population	http://purl.obolibrary.org/obo/OBI_0000181	population		A population where the collection of individuals is located and maintained in a laboratory, research, or production facility.
http://purl.obolibrary.org/obo/OBI_2100402	pooled clone sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay		A DNA sequencing assay in which the DNA input is derived from pooled clones (for example BACs and Fosmids) is sequenced.
http://purl.obolibrary.org/obo/OBI_0003710	assessment of startle response in an organism	http://purl.obolibrary.org/obo/OBI_0003533	nervous system functionality assessment		A nervous system functionality assessment of auditory startle response in an organism in an anechoic chamber by exposing to sound.
http://purl.obolibrary.org/obo/IAO_8000001	base ontology module	http://purl.obolibrary.org/obo/IAO_8000000	ontology module		An ontology module that comprises only of asserted axioms local to the ontology, excludes import directives, and excludes axioms or declarations from external ontologies.
http://purl.obolibrary.org/obo/IAO_8000003	main release ontology module	http://purl.obolibrary.org/obo/IAO_8000000	ontology module		An ontology module that is intended to be the primary release product and the one consumed by the majority of tools.
http://purl.obolibrary.org/obo/IAO_8000004	bridge ontology module	http://purl.obolibrary.org/obo/IAO_8000000	ontology module		An ontology module that consists entirely of axioms that connect or bridge two distinct ontology modules. For example, the Uberon-to-ZFA bridge module.
http://purl.obolibrary.org/obo/IAO_8000007	curation subset ontology module	http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module		A subset ontology that is intended as a whitelist for curators using the ontology. Such a subset will exclude classes that curators should not use for curation.
http://purl.obolibrary.org/obo/IAO_8000008	analysis subset ontology module	http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module		An ontology module that is intended for usage in analysis or discovery applications.
http://purl.obolibrary.org/obo/IAO_8000013	reasoned ontology module	http://purl.obolibrary.org/obo/IAO_8000000	ontology module		An ontology module that contains axioms generated by a reasoner. The generated axioms are typically direct SubClassOf axioms, but other possibilities are available.
http://purl.obolibrary.org/obo/IAO_8000014	generated ontology module	http://purl.obolibrary.org/obo/IAO_8000000	ontology module		An ontology module that is automatically generated, for example via a SPARQL query or via template and a CSV.
http://purl.obolibrary.org/obo/IAO_8000015	template generated ontology module	http://purl.obolibrary.org/obo/IAO_8000014	generated ontology module		An ontology module that is automatically generated from a template specification and fillers for slots in that template.
http://purl.obolibrary.org/obo/IAO_8000018	obo basic subset ontology module	http://purl.obolibrary.org/obo/IAO_8000017	ontology module subsetted by expressivity		A subset ontology that is designed for basic applications to continue to make certain simplifying assumptions; many of these simplifying assumptions were based on the initial version of the Gene Ontology, and have become enshrined in many popular and useful tools such as term enrichment tools.

Examples of such assumptions include: traversing the ontology graph ignoring relationship types using a naive algorithm will not lead to cycles (i.e. the ontology is a DAG); every referenced term is declared in the ontology (i.e. there are no dangling clauses).

An ontology is OBO Basic if and only if it has the following characteristics:
DAG
Unidirectional
No Dangling Clauses
Fully Asserted
Fully Labeled
No equivalence axioms
Singly labeled edges
No qualifier lists
No disjointness axioms
No owl-axioms header
No imports
http://purl.obolibrary.org/obo/CHEBI_145810	insulin	http://purl.obolibrary.org/obo/CHEBI_16670	peptide		A peptide hormone which consists of two polypeptide chains, A- and B- chains which are linked together by disulfide bonds. The amino acid sequence of insulin varies across species and certain segments of the molecule are highly conserved. In most species, the A chain consists of 21 amino acids and the B chain consists of 30 amino acids. In mammals, insulin is synthesised in the pancreas within the beta cells whereas in certain species of fish, the insulin-producing tissue is uniquely located in separate structures called Brockmann bodies.
http://purl.obolibrary.org/obo/PR_000050219	alanine aminotransferase	http://purl.obolibrary.org/obo/PR_000000001	protein		A protein that is a translation product of the human GPT or GPT2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof.
http://purl.obolibrary.org/obo/OBI_0003230	T cell activation induced marker assay	http://purl.obolibrary.org/obo/OBI_0000916	flow cytometry assay		A flow cytometry assay that detects the presence/amount of antigen-specific T cells without the need to identify their cytokine production. Instead, antigen-specific T cells are detected on the basis of upregulation of TCR stimulation-induced surface markers.
http://purl.obolibrary.org/obo/OBI_0002776	cytometry analysis by automated gating	http://purl.obolibrary.org/obo/OBI_0200077	gating		A gating in which the output of a flow- or mass- cytometry experiment is separated into gates that were set by an algorithm in order to quantify the frequency of different cell populations of interest.
http://purl.obolibrary.org/obo/OBI_0003291	in silico design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that is executed primarily on a computer.
http://purl.obolibrary.org/obo/OBI_0002830	catheter	http://purl.obolibrary.org/obo/OBI_0000968	device		A device which is a flexible tube inserted into a body and which enables transfer of fluids into or out of a body.
http://purl.obolibrary.org/obo/OBI_0003299	DamID-seq	http://purl.obolibrary.org/obo/OBI_0003298	DNA adenine methyltransferase identification assay		A DNA adenine methyltransferase identification (DamID) assay in which DamID-generated DNA fragments undergo high-throughput sequencing to determine a protein's DNA-binding site.
http://purl.obolibrary.org/obo/OBI_0003301	DNase Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay		A Hi-C assay in which DNase I is used for digesting DNA fragments rather than a restriction enzyme, which can result in a higher resolution of mapped chromosome contacts.
http://purl.obolibrary.org/obo/OBI_0003302	micro-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay		A Hi-C assay which uses micrococcal nuclease digestion in place of the restriction enzyme digestion step.
http://purl.obolibrary.org/obo/OBI_0003305	single cell Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay		A Hi-C assay performed on a single cell.
http://purl.obolibrary.org/obo/OBI_0003306	bulk Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay		A Hi-C assay in which the sample that is sequenced is derived from a collection of cells, such as a tissue sample or entire cell culture, and therefore provides results representative of the aggregate of sample cells.
http://purl.obolibrary.org/obo/OBI_0003317	perforin release during T cell degranulation	http://purl.obolibrary.org/obo/GO_0035944	perforin production		The release of perforin during cytotoxic T cell degranulation.
http://purl.obolibrary.org/obo/OBI_0003318	granzyme A release during T cell degranulation	http://purl.obolibrary.org/obo/GO_0035746	granzyme A production		The release of granzyme A during cytotoxic T cell degranulation.
http://purl.obolibrary.org/obo/OBI_0003319	granzyme B release during T cell degranulation	http://purl.obolibrary.org/obo/GO_0071613	granzyme B production		The release of granzyme B during cytotoxic T cell degranulation.
http://purl.obolibrary.org/obo/OBI_0003320	granulysin release during T cell degranulation	http://purl.obolibrary.org/obo/GO_0036262	granulysin production		The release of granulysin during cytotoxic T cell degranulation.
http://purl.obolibrary.org/obo/OBI_0003321	venous blood microbiology assay	http://purl.obolibrary.org/obo/OBI_0002649	blood microbiology assay		A blood microbiology assay that detects a microorganism in a venous blood specimen.
http://purl.obolibrary.org/obo/OBI_0003324	high throughput multiplexed assay measuring binding of a T cell epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_1110037	assay measuring binding of a T cell epitope:MHC:TCR complex		A T cell epitope assay that measures the binding of T cell receptor to an epitope using a high throughput multiplexed assay.
http://purl.obolibrary.org/obo/OBI_0003326	high throughput multiplexed assay measuring MHC ligand processing and presentation	http://purl.obolibrary.org/obo/OBI_1110125	assay measuring MHC ligand processing and presentation		A MHC ligand assay that determines what ligands are processed and loaded onto MHC molecules by eluting ligands and identifying them using a high throughput multiplexed assay.
http://purl.obolibrary.org/obo/OBI_0003367	diagnosis of an organism	http://purl.obolibrary.org/obo/OBI_0001909	conclusion based on data		A conclusion based on data about that an organism has a disease, disorder, or syndrome of a certain type, or none of these.
http://purl.obolibrary.org/obo/OBI_0003368	detection technique	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay (A) that is part of another assay (B), where the target entities of A and B are disjoint, and the target entity of A is a proxy for the target of assay B.
http://purl.obolibrary.org/obo/OBI_0003369	assay kit	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that consists of reagents and devices that enable the performance of a specific type of assay, which could, in addition, require specific instruments not included in the kit.
http://purl.obolibrary.org/obo/OBI_0003371	epitope specific XCL1 release by T cells	http://purl.obolibrary.org/obo/GO_0140779	XCL1 production		A biological process where T cells produce XCL1 resulting from the recognition of a T cell epitope.
http://purl.obolibrary.org/obo/OBI_0003372	assay measuring epitope specific lymphotactin production by T cells	http://purl.obolibrary.org/obo/OBI_1110129	assay measuring epitope specific cytokine production by T cells		A T cell epitope specific cytokine production assay that detects lymphotactin production by T cells.
http://purl.obolibrary.org/obo/OBI_0003373	ELISA measuring epitope specific lymphotactin production by T cells	http://purl.obolibrary.org/obo/OBI_0003372	assay measuring epitope specific lymphotactin production by T cells		An enzyme-linked immunosorbent assay that detects lymphotactin production by T cells.
http://purl.obolibrary.org/obo/OBI_0003380	placental blood specimen	http://purl.obolibrary.org/obo/OBI_0000655	blood specimen		A specimen that is derived from placental blood.
http://purl.obolibrary.org/obo/OBI_0003381	placental blood microbiology assay	http://purl.obolibrary.org/obo/OBI_0002649	blood microbiology assay		A blood microbiology assay that detects microorganisms in a placental blood specimen.
http://purl.obolibrary.org/obo/OBI_0003382	placental blood microbiology datum	http://purl.obolibrary.org/obo/OBI_0003244	blood microbiology datum		An organism detection datum that is the specified output of a placental blood microbiology assay.
http://purl.obolibrary.org/obo/OBI_0003383	eukaryota in placental blood datum	http://purl.obolibrary.org/obo/OBI_0003382	placental blood microbiology datum		A placental blood microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003691	liquid nitrogen bath	http://purl.obolibrary.org/obo/OBI_0400120	temperature control bath		A temperature control bath in which liquid nitrogen acts as contact medium providing a constant temperature of −195.8 °C at 1 atm.
http://purl.obolibrary.org/obo/OBI_0003688	sand bath	http://purl.obolibrary.org/obo/OBI_0400120	temperature control bath		A temperature control bath in which sand acts as contact medium for the temperature transfer (from heating or cooling elements to the sample).
http://purl.obolibrary.org/obo/OBI_0003695	nested case-control investigation	http://purl.obolibrary.org/obo/OBI_0003692	case-control investigation		A case–control investigation in which cases and controls are drawn from the population in a fully enumerated cohort.
http://purl.obolibrary.org/obo/OBI_0003727	minimum data transformation	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		A data transformation that has as its output the least value in the input data set.
http://purl.obolibrary.org/obo/CL_0011114	segmented neutrophil of bone marrow	http://purl.obolibrary.org/obo/CL_0000775	neutrophil		A segmented neutrophilic cell of the bone marrow reserve pool that expresses CD11b (integrin alpha-M) and high levels of CD16 (low affinity immunoglobulin gamma Fc region receptor III) on its cell surface.
http://purl.obolibrary.org/obo/OBI_0002570	nCounter Mouse miRNA Expression array	http://purl.obolibrary.org/obo/OBI_0001865	assay array		A mouse array which is manufacutred by NanoString Technologies. Built upon color-coded molecular barcodes technology, the array profiles miRNA with increased specificity and sensitivty than microarrays.
http://purl.obolibrary.org/obo/OBI_0003131	directed mutagenesis	http://purl.obolibrary.org/obo/OBI_0001154	induced mutagenesis		An induced mutation in which a specific gene(s) or part of a gene(s) is altered.
http://purl.obolibrary.org/obo/OBI_0003276	eukaryota in nasopharyngeal or oropharyngeal swab datum	http://purl.obolibrary.org/obo/OBI_0003257	nasopharyngeal or oropharyngeal swab microbiology datum		A nasopharyngeal or oropharyngeal swab microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003277	virus in nasopharyngeal or oropharyngeal swab datum	http://purl.obolibrary.org/obo/OBI_0003257	nasopharyngeal or oropharyngeal swab microbiology datum		A nasopharyngeal or oropharyngeal swab microbiology datum that is about a virus.
http://purl.obolibrary.org/obo/OBI_0003278	bacteria in pleural fluid datum	http://purl.obolibrary.org/obo/OBI_0003258	pleural fluid microbiology datum		A pleural fluid microbiology datum that is about bacteria.
http://purl.obolibrary.org/obo/OBI_0003279	eukaryota in pleural fluid datum	http://purl.obolibrary.org/obo/OBI_0003258	pleural fluid microbiology datum		A pleural fluid microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003280	virus in pleural fluid datum	http://purl.obolibrary.org/obo/OBI_0003258	pleural fluid microbiology datum		A pleural fluid microbiology datum that is about a virus.
http://purl.obolibrary.org/obo/OBI_0003281	eukaryota in umbilical cord blood datum	http://purl.obolibrary.org/obo/OBI_0003263	eukaryota in blood datum		An umbilical cord blood microbiology datum that is about eukaryota.
http://purl.obolibrary.org/obo/OBI_0003282	lung microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a lung specimen.
http://purl.obolibrary.org/obo/OBI_0003286	urine microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a urine specimen.
http://purl.obolibrary.org/obo/OBI_0003294	modified acid-fast stain microscopy assay	http://purl.obolibrary.org/obo/OBI_0002119	microscopy assay		A microscopy assay that uses staining to identify acid-fast organisms in a specimen and does not require heating.
http://purl.obolibrary.org/obo/OBI_0002777	cytometry analysis by manual gating	http://purl.obolibrary.org/obo/OBI_0200077	gating		A gating in which the output of a flow- or mass- cytometry experiment is separated into gates that were set by a human operator in order to quantify the frequency of different cell populations of interest.
http://purl.obolibrary.org/obo/OBI_0002816	chromatography vial	http://purl.obolibrary.org/obo/OBI_0000601	chromatography consumable		A vial with cap and container material suited to optical, sanitary and handling requirements of chromatography.
http://purl.obolibrary.org/obo/OBI_0003088	autofluorescence microscopy assay	http://purl.obolibrary.org/obo/OBI_0003087	autofluorescence assay		An autofluorescence assay in which the light that is naturally emitted by a sample is visualized via microscopy after excitation of the sample with light at a suitable wavelength.
http://purl.obolibrary.org/obo/OBI_0003090	bulk RNA-seq assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay		An RNA-seq assay in which the sample that is sequenced is derived from a collection of cells, such as a tissue sample or entire cell culture, and therefore provides results representative of the aggregate of sample cells.
http://purl.obolibrary.org/obo/OBI_0003091	multiplexed fluorescent antibody imaging assay	http://purl.obolibrary.org/obo/OBI_0000185	imaging assay		An imaging assay in which multiple cycles consisting of fluorescent labeling, imaging, and fluorophor deactivation are used to detect multiple proteins and their locations in a given sample of tissues or cells.
http://purl.obolibrary.org/obo/OBI_0003092	Cell DIVE multiplexed imaging assay	http://purl.obolibrary.org/obo/OBI_0003091	multiplexed fluorescent antibody imaging assay		A multiplexed fluorescent antibody imaging assay that involves an iterative staining, imaging and dye inactivation workflow for over 60 biomarkers on a single fixed tissue section.
http://purl.obolibrary.org/obo/OBI_0003098	lightsheet fluorescence microscopy assay	http://purl.obolibrary.org/obo/CHMO_0000087	fluorescence microscopy assay		A fluorescence microscopy that involves capturing of photons emitted by fluorophores excited with a thin sheet of laser light in a sample only in a relatively narrow plane by a detection objective oriented perpendicularly to the light sheet and imaged onto a detection device such as a CCD camera.
http://purl.obolibrary.org/obo/OBI_0003107	slide-seq assay	http://purl.obolibrary.org/obo/OBI_0001271	RNA-seq assay		An RNA-seq assay that involves transfer of RNA from tissue sections onto a surface covered in DNA-barcoded beads with known positions, allowing the locations of the RNA to be inferred by sequencing.
http://purl.obolibrary.org/obo/OBI_0003111	SOMAscan assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that uses aptamers to detect protein analytes in serum.
http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay	http://purl.obolibrary.org/obo/OBI_0000920	cytometric bead array assay		A cytometric bead array assay in which a series of beads are coated with antibodies specific to antigens of interest. Antigens of interest attach to antibodies on the beads. Fluorescent labeled secondary antibodies are used to detect the antigens of interest.
http://purl.obolibrary.org/obo/OBI_0003117	3D molecular structure determination assay	http://purl.obolibrary.org/obo/OBI_0600045	3D structure determination assay		An assay that determines the 3-dimensional configuration of a molecular entity or molecular complex.
http://purl.obolibrary.org/obo/OBI_0003118	electron-microscopy 3D molecular structure determination assay	http://purl.obolibrary.org/obo/OBI_0003117	3D molecular structure determination assay		A 3D molecular structure determination assay that uses electron microscopy imaging.
http://purl.obolibrary.org/obo/OBI_0003119	antigen:antibody complex	http://purl.obolibrary.org/obo/COB_0000080	complex of molecules		A complex of molecular entitites which is the result of an antibody binding to an antigen.
http://purl.obolibrary.org/obo/OBI_0003120	epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/COB_0000080	complex of molecules		A complex of molecular entities which is the result of a T cell receptor binding to a MHC-epitope complex.
http://purl.obolibrary.org/obo/OBI_0003121	MHC:ligand complex	http://purl.obolibrary.org/obo/COB_0000080	complex of molecules		A complex of molecular entities which is the result of a MHC molecule binding with a ligand.
http://purl.obolibrary.org/obo/OBI_0003122	3D cell structure determination assay	http://purl.obolibrary.org/obo/OBI_0600045	3D structure determination assay		A 3D structure determination assay that determines the 3-dimensional configuration of a cell.
http://purl.obolibrary.org/obo/OBI_0003123	3D neural cell structure determination assay	http://purl.obolibrary.org/obo/OBI_0003122	3D cell structure determination assay		A 3D cell structure determination assay that determines the 3-dimensional configuration of a neural cell.
http://purl.obolibrary.org/obo/OBI_0003124	neuron morphology assay	http://purl.obolibrary.org/obo/OBI_0003123	3D neural cell structure determination assay		A 3D neural cell structure determination assay that determines the 3-dimensional configuration of a neuron.
http://purl.obolibrary.org/obo/OBI_0003126	neuron morphology reconstruction assay	http://purl.obolibrary.org/obo/OBI_0003124	neuron morphology assay		A neuron morphology assay where the morphology or structure of a neuron is represented. Often, this assay is a combination of different assays (sparse labelling, fluorescent labeling, fMOST).
http://purl.obolibrary.org/obo/OBI_0003128	T cell epitope assay	http://purl.obolibrary.org/obo/OBI_1110128	immune epitope assay		An immune epitope assay that characterizes the structrue of an epitope-T cell receptor complex, or measures the binding of a T cell receptor to epitope, or the immune response process resulting from such a binding event or the recognition of the epitope.
http://purl.obolibrary.org/obo/OBI_0003129	chemical mutagenesis	http://purl.obolibrary.org/obo/OBI_0002620	random mutagenesis		A form of random mutagenesis that produces a mutation by introducing the organism to a chemical mutagen.
http://purl.obolibrary.org/obo/OBI_0003132	endonuclease mediated mutagenesis	http://purl.obolibrary.org/obo/OBI_0003131	directed mutagenesis		A directed mutagenesis in which guide RNAs and an endonuclease (cas9, TALEN) are used to introduce a mutation at a specific location in a gene.
http://purl.obolibrary.org/obo/OBI_0003134	TALEN mediated mutagenesis	http://purl.obolibrary.org/obo/OBI_0003132	endonuclease mediated mutagenesis		An endonuclease mediated mutagenesis in which guide RNAs and transcription activator-like effector nucleases (TALENs) are used to introduce a mutation at a specific location in the genome.
http://purl.obolibrary.org/obo/OBI_0003136	transgenic mutagenesis	http://purl.obolibrary.org/obo/OBI_0002620	random mutagenesis		A form of random mutagenesis that produces a mutation by introducing a construct into the genome of an organism in a random or semi-random fashion.
http://purl.obolibrary.org/obo/OBI_0003137	gene-trap mutagenesis	http://purl.obolibrary.org/obo/OBI_0003136	transgenic mutagenesis		A transgenic mutagenesis that produces a mutation by introducing a construct designed to capture the expression of an endogenous gene by creating a spliced fusion transcript when inserted into the genome of an organism.
http://purl.obolibrary.org/obo/OBI_0003138	enhancer-trap mutagenesis	http://purl.obolibrary.org/obo/OBI_0003136	transgenic mutagenesis		A transgenic mutagenesis that produces a mutation by introducing a construct designed to monitor transcriptionally active regions when inserted into the genome of an organism by inserting a reporter gene that requires cis-acting DNA sequences in the genome to activate reporter gene expression.
http://purl.obolibrary.org/obo/OBI_0003140	transposon-induced mutagenesis	http://purl.obolibrary.org/obo/OBI_0002620	random mutagenesis		A random mutagenesis in which expression of a transposase causes the mobilization of an artificial or modified transposable element with the insertion of the element into the genome creating a mutation.
http://purl.obolibrary.org/obo/OBI_0003142	quantitative binding datum	http://purl.obolibrary.org/obo/OBI_0001181	binding datum		A binding datum that is expressed using numbers.
http://purl.obolibrary.org/obo/OBI_0003143	EC50 binding datum	http://purl.obolibrary.org/obo/OBI_0003142	quantitative binding datum		A quantitative binding datum that is expressed as a half-maximal effective concentration (EC50).
http://purl.obolibrary.org/obo/OBI_0003144	IC50 binding datum	http://purl.obolibrary.org/obo/OBI_0003142	quantitative binding datum		A quantitative binding datum that is expressed as a half-maximal inhibitory concentration (IC50).
http://purl.obolibrary.org/obo/OBI_0003147	assay measuring quantitative binding of an epitope:MHC:TCR complex	http://purl.obolibrary.org/obo/OBI_1110037	assay measuring binding of a T cell epitope:MHC:TCR complex		An assay that detects the binding of a MHC:epitope complex with a T cell receptor, and produces a quantitative measurement of the binding as an output.
http://purl.obolibrary.org/obo/OBI_0003148	albumin concentration assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An albumin assay that measures the concentration of albumin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003150	calcium cation concentration assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		A calcium cation assay that measures the concentration of calcium cations in a specimen.
http://purl.obolibrary.org/obo/OBI_0003151	chloride concentration assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		A chloride assay that measures the concentration of chloride in a specimen.
http://purl.obolibrary.org/obo/OBI_0003152	cholesterol concentration assay	http://purl.obolibrary.org/obo/OBI_2100031	cholesterol assay		A cholesterol assay that measures the concentration of cholesterol in a specimen.
http://purl.obolibrary.org/obo/OBI_0003153	creatinine concentration assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		A creatinine assay that measures the concentration of creatinine in a specimen.
http://purl.obolibrary.org/obo/OBI_0003154	eosinophil percentage assay	http://purl.obolibrary.org/obo/OBI_0003023	eosinophil assay		An eosinophil assay that measures the percentage of eosinophils in a specimen.
http://purl.obolibrary.org/obo/OBI_0003155	globulin concentration assay	http://purl.obolibrary.org/obo/OBI_0003015	globulin assay		A globulin assay that measures the concentration of globulin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003156	hemoglobin concentration assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		A hemoglobin assay that measures the amount of hemoglobin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003157	high-density lipoprotein cholesterol concentration assay	http://purl.obolibrary.org/obo/OBI_2100030	high-density lipoprotein cholesterol assay		A high-density lipoprotein cholesterol assay that measures the concentration of high-density lipoprotein cholesterol in a specimen.
http://purl.obolibrary.org/obo/OBI_0003158	iron concentration assay	http://purl.obolibrary.org/obo/OBI_0003011	iron assay		An iron assay that measures the concentration of iron cation in a specimen.
http://purl.obolibrary.org/obo/OBI_0003159	low-density lipoprotein cholesterol concentration assay	http://purl.obolibrary.org/obo/OBI_2100032	low-density lipoprotein cholesterol assay		A low-density lipoprotein cholesterol assay that measures the concentration of low-density lipoprotein cholesterol in a specimen.
http://purl.obolibrary.org/obo/OBI_0003160	lymphocyte percentage assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A lymphocyte assay that measures the percentage of lymphocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003161	metamyelocyte count assay	http://purl.obolibrary.org/obo/OBI_0003017	metamyelocyte assay		A metamyelocyte assay that measures the number of metamyelocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003162	metamyelocyte percentage assay	http://purl.obolibrary.org/obo/OBI_0003017	metamyelocyte assay		A metamyelocyte assay that measures the percentage of metamyelocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003163	methemoglobin percentage assay	http://purl.obolibrary.org/obo/OBI_2100040	methemoglobin assay		A methemoglobin assay that measures the percentage of methemoglobin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003164	monocyte percentage assay	http://purl.obolibrary.org/obo/OBI_0003025	monocyte assay		A monocyte assay that measures the percentage of monocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003165	myelocyte count assay	http://purl.obolibrary.org/obo/OBI_0003016	myelocyte assay		A myelocyte assay that measures the number of myelocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003166	neutrophil percentage assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A neutrophil assay that measures the percentage of neutrophils in a specimen.
http://purl.obolibrary.org/obo/OBI_0003167	phosphate ion concentration assay	http://purl.obolibrary.org/obo/OBI_2100015	phosphate ion assay		A phosphate ion assay that measures the concentration of phosphate ions in a specimen.
http://purl.obolibrary.org/obo/OBI_0003168	potassium(1+) concentration assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		A potassium(1+) assay that measures the concentration of potassium(1+) in a specimen.
http://purl.obolibrary.org/obo/OBI_0003170	reticulocyte percentage assay	http://purl.obolibrary.org/obo/OBI_0003026	reticulocyte assay		A reticulocyte assay that measures the percentage of reticulocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003171	sodium(1+) concentration assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		A sodium(1+) assay that measures the concentration of sodium(1+) in a specimen.
http://purl.obolibrary.org/obo/OBI_0003172	thyroid stimulating hormone concentration assay	http://purl.obolibrary.org/obo/OBI_2100033	thyroid stimulating hormone assay		A thyroid stimulating hormone assay that measures the concentration of thyroid stimulating hormone in a specimen.
http://purl.obolibrary.org/obo/OBI_0003173	triglyceride concentration assay	http://purl.obolibrary.org/obo/OBI_2100029	triglyceride assay		A triglyceride assay that measures the concentration of triglycerides in a specimen.
http://purl.obolibrary.org/obo/OBI_0003174	3,3',5'-triiodothyronine concentration assay	http://purl.obolibrary.org/obo/OBI_2100046	3,3',5'-triiodothyronine assay		A 3,3',5'-triiodothyronine assay that measures the concentration of 3,3',5'-triiodothyronine in a specimen.
http://purl.obolibrary.org/obo/OBI_0003175	fibrinogen concentration assay	http://purl.obolibrary.org/obo/OBI_0003010	fibrinogen assay		A fibrinogen assay that measures the concentration of fibrinogen in a specimen.
http://purl.obolibrary.org/obo/OBI_0003176	free thyroxine concentration assay	http://purl.obolibrary.org/obo/OBI_2100035	thyroxine assay		A thyroxine assay that measures the concentration of free thyroxine in a specimen.
http://purl.obolibrary.org/obo/OBI_0003177	total thyroxine concentration assay	http://purl.obolibrary.org/obo/OBI_2100035	thyroxine assay		A thyroxine assay that measures the concentration of total thyroxine in a specimen.
http://purl.obolibrary.org/obo/OBI_0003180	direct bilirubin concentration assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		A bilirubin IXalpha assay that measures the concentration of direct bilirubin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003181	indirect bilirubin concentration assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		A bilirubin IXalpha assay that measures the concentration of indirect bilirubin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003182	total bilirubin concentration assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		A bilirubin IXalpha assay that measures the concentration of total bilirubin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003183	mean cell hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		A hemoglobin assay that measures the average concentration of hemoglobin in a population of erythrocytes.
http://purl.obolibrary.org/obo/OBI_0003184	mean cell hemoglobin concentration assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		A hemoglobin assay that measures the concentration of hemoglobin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003185	mean platelet volume assay	http://purl.obolibrary.org/obo/OBI_0003028	platelet assay		A platelet assay that measures the average volume of platelets in a specimen.
http://purl.obolibrary.org/obo/OBI_0003186	immature neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A neutrophil assay that measures the number of immature neutrophils in a specimen.
http://purl.obolibrary.org/obo/OBI_0003187	immature neutrophil percentage assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		An neutrophil assay that measures the percentage of immature neutrophils in a specimen.
http://purl.obolibrary.org/obo/OBI_0003188	nucleated erythrocyte percentage assay	http://purl.obolibrary.org/obo/OBI_0003190	erythrocyte assay		An erythrocyte assay that measures the percentage of nucleated erythrocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003189	mean cell volume assay	http://purl.obolibrary.org/obo/OBI_0003190	erythrocyte assay		An erythrocyte assay that measures the average volume of erythrocytes in a specimen.
http://purl.obolibrary.org/obo/OBI_0003190	erythrocyte assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the abundance and/or characteristics of erythrocytes.
http://purl.obolibrary.org/obo/OBI_0003191	manual hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A hematocrit assay that measures the percentage of erythrocytes in a specimen by manual processes.
http://purl.obolibrary.org/obo/OBI_0003192	adiponectin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of adiponectin
http://purl.obolibrary.org/obo/OBI_0003193	adiponectin concentration assay	http://purl.obolibrary.org/obo/OBI_0003192	adiponectin assay		An adiponectin assay that measures the concentration of adiponectin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003194	creatine assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of creatine
http://purl.obolibrary.org/obo/OBI_0003195	creatine concentration assay	http://purl.obolibrary.org/obo/OBI_0003194	creatine assay		A creatine assay that measures the concentration of creatine in a specimen.
http://purl.obolibrary.org/obo/OBI_0003196	estradiol assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of estradiol
http://purl.obolibrary.org/obo/OBI_0003197	estradiol concentration assay	http://purl.obolibrary.org/obo/OBI_0003196	estradiol assay		An estradiol assay that measures the concentration of estradiol in a specimen.
http://purl.obolibrary.org/obo/OBI_0003202	leptin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of leptin
http://purl.obolibrary.org/obo/OBI_0003203	leptin concentration assay	http://purl.obolibrary.org/obo/OBI_0003202	leptin assay		An leptin assay that measures the concentration of leptin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003204	lipoprotein concentration assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of lipoprotein
http://purl.obolibrary.org/obo/OBI_0003205	high-density lipoprotein concentration assay	http://purl.obolibrary.org/obo/OBI_0003204	lipoprotein concentration assay		A lipoprotein concentration assay that measures the concentration of high-density lipoprotein in a specimen.
http://purl.obolibrary.org/obo/OBI_0003206	low-density lipoprotein concentration assay	http://purl.obolibrary.org/obo/OBI_0003204	lipoprotein concentration assay		A lipoprotein concentration assay that measures the concentration of low-density lipoprotein in a specimen.
http://purl.obolibrary.org/obo/OBI_0003207	very-low-density lipoprotein concentration assay	http://purl.obolibrary.org/obo/OBI_0003204	lipoprotein concentration assay		A lipoprotein concentration assay that measures the concentration of very-low-density lipoprotein in a specimen.
http://purl.obolibrary.org/obo/OBI_0003208	luteinizing hormone assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of luteinizing hormone
http://purl.obolibrary.org/obo/OBI_0003209	luteinizing hormone concentration assay	http://purl.obolibrary.org/obo/OBI_0003208	luteinizing hormone assay		A luteinizing hormone assay that measures the concentration of luteinizing hormone in a specimen.
http://purl.obolibrary.org/obo/OBI_0003210	nitrite assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of nitrite
http://purl.obolibrary.org/obo/OBI_0003211	nitrite concentration assay	http://purl.obolibrary.org/obo/OBI_0003210	nitrite assay		A nitrite assay that measures the concentration of nitrite in a specimen.
http://purl.obolibrary.org/obo/OBI_0003212	phospholipid assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of phospholipid
http://purl.obolibrary.org/obo/OBI_0003213	phospholipid concentration assay	http://purl.obolibrary.org/obo/OBI_0003212	phospholipid assay		A phospholipid assay that measures the concentration of phospholipids in a specimen.
http://purl.obolibrary.org/obo/OBI_0003214	progesterone assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of progesterone
http://purl.obolibrary.org/obo/OBI_0003215	progesterone concentration assay	http://purl.obolibrary.org/obo/OBI_0003214	progesterone assay		A progesterone assay that measures the concentration of progesterone in a specimen.
http://purl.obolibrary.org/obo/OBI_0003216	testosterone assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of testosterone
http://purl.obolibrary.org/obo/OBI_0003217	testosterone concentration assay	http://purl.obolibrary.org/obo/OBI_0003216	testosterone assay		A testosterone assay that measures the concentration of testosterone in a specimen.
http://purl.obolibrary.org/obo/OBI_0003218	bile salt assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of bile salt
http://purl.obolibrary.org/obo/OBI_0003219	bile salt concentration assay	http://purl.obolibrary.org/obo/OBI_0003218	bile salt assay		A bile salt assay that measures the concentration of bile salt in a specimen.
http://purl.obolibrary.org/obo/OBI_0003220	fatty acid assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of fatty acid
http://purl.obolibrary.org/obo/OBI_0003221	free fatty acid concentration assay	http://purl.obolibrary.org/obo/OBI_0003220	fatty acid assay		A fatty acid assay that measures the concentration of free fatty acids in a specimen.
http://purl.obolibrary.org/obo/OBI_0003222	insulin assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of insulin
http://purl.obolibrary.org/obo/OBI_0003223	insulin concentration assay	http://purl.obolibrary.org/obo/OBI_0003222	insulin assay		A insulin assay that measures the concentration of insulin in a specimen.
http://purl.obolibrary.org/obo/OBI_0003224	follicle stimulating hormone assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of follicle stimulating hormone
http://purl.obolibrary.org/obo/OBI_0003225	follicle stimulating hormone concentration assay	http://purl.obolibrary.org/obo/OBI_0003224	follicle stimulating hormone assay		A follicle stimulating hormone assay that measures the concentration of follicle stimulating hormone in a specimen.
http://purl.obolibrary.org/obo/OBI_0003226	total lymphocyte count assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A lymphocyte assay that measures the number of lymphocytes and large unstained cells in a specimen.
http://purl.obolibrary.org/obo/OBI_0003227	total lymphocyte percentage assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A lymphocyte assay that measures the percentage of lymphocytes and large unstained cells in a specimen.
http://purl.obolibrary.org/obo/OBI_0003293	cytometric bead array assay measuring epitope specific perforin release by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects epitope specific perforin release by T cells.
http://purl.obolibrary.org/obo/OBI_0003295	positive binding datum	http://purl.obolibrary.org/obo/OBI_0003141	categorical binding datum		A categorical binding datum that states that there is a significant disposition of two or more entities to form a complex.
http://purl.obolibrary.org/obo/OBI_0003366	organism diagnostic process	http://purl.obolibrary.org/obo/OBI_0000338	drawing a conclusion based on data		A drawing a conclusion based on data that involves the interpretation of data about a given organism (human, animal, or plant) and the assertion to the effect that the organism has or had a disease, disorder, or syndrome of a certain type, or none of these as output.
http://purl.obolibrary.org/obo/OBI_0003323	high throughput multiplexed assay measuring binding of a B cell epitope:antibody complex	http://purl.obolibrary.org/obo/OBI_1110127	assay measuring binding of a B cell epitope:antibody complex		A B cell epitope assay that measures the binding of an antibody receptor to an epitope using a high throughput multiplexed assay.
http://purl.obolibrary.org/obo/OBI_0003414	administering substance in vivo to reduce or prevent disease	http://purl.obolibrary.org/obo/OBI_0600007	administering substance in vivo		An administration of substance in vivo with the intention to reduce the symptoms of or prevent development of a disease in the organism.
http://purl.obolibrary.org/obo/COB_0001000	exposure of organism	http://purl.obolibrary.org/obo/BFO_0000015	process		A process during which an organism comes into contact with another entity.
http://purl.obolibrary.org/obo/OBI_0003328	magnetic resonance image data set	http://purl.obolibrary.org/obo/OBI_0003327	image data set		An image data set whose information content originates from some MR imaging assay and is about some MRI participant.
http://purl.obolibrary.org/obo/OBI_0003329	magnetic resonance imaging participant	http://purl.obolibrary.org/obo/BFO_0000040	material entity		The subject being scanned in an MRI study, and bearor of data derived from that study.
http://purl.obolibrary.org/obo/OBI_0003330	magnetic resonance imaging evaluant role	http://purl.obolibrary.org/obo/OBI_0000067	evaluant role		An evaluant role that inheres in a material entity that is realized in a MR imaging assay in which MR imaging data is generated about the bearer of the evaluant role.
http://purl.obolibrary.org/obo/OBI_0003331	raw image data set	http://purl.obolibrary.org/obo/OBI_0003327	image data set		An image data set that encodes measurement values produced by some instrument before undergoing a data transformation.
http://purl.obolibrary.org/obo/OBI_0003332	magnetic resonance pulse sequence protocol	http://purl.obolibrary.org/obo/OBI_0000272	protocol		The NMR/MRI machine protocol about the radiofrequency pulse sequence.
http://purl.obolibrary.org/obo/OBI_0003355	image data set analysis	http://purl.obolibrary.org/obo/OBI_0200000	data transformation		The process of deriving a data item from an image data set using computer algorithms. The produced data item can be an image data set, data measurement, or any other data item.
http://purl.obolibrary.org/obo/OBI_0003489	Scrub Typhus Detect IgM ELISA kit	http://purl.obolibrary.org/obo/OBI_0003369	assay kit		An assay kit that is manufactured by InBios International to use ELISA to test for IgM antibodies for Orientia tsutsugamushi strains Karp, Kato, Gilliam, and TA 716, with a protein microarray that has a 96-well plate and the 56-kDa type-specific antigen.
http://purl.obolibrary.org/obo/OBI_0003490	Panbio Dengue IgM capture ELISA kit	http://purl.obolibrary.org/obo/OBI_0003369	assay kit		An assay kit that is manufactured by Abbott to test for IgM antibodies for Dengue with a two-plate protein microarray. One plate contains stabilized Dengue viruses 1 through 4, and the other plate contains anti-human IgM antibody.
http://purl.obolibrary.org/obo/OBI_0003491	Panbio Dengue Early ELISA kit	http://purl.obolibrary.org/obo/OBI_0003369	assay kit		An assay kit that is manufactured by Abbott to detect the NS1 Dengue viral protein with a protein microarray and an anti-NS1 monoclonal antibody.
http://purl.obolibrary.org/obo/OBI_0003492	SD Bioline Chikungunya IgM RDT kit	http://purl.obolibrary.org/obo/OBI_0003369	assay kit		A device manufactured by Abbott for rapid detection of human IgM antibodies for Chikungunya virus in blood, using analytical chromatography.
http://purl.obolibrary.org/obo/OBI_0003493	SD Bioline Chikungunya IgM capture ELISA kit	http://purl.obolibrary.org/obo/OBI_0003369	assay kit		An assay kit that is manufactured by Abbott to detect human IgM antibodies for Chikungunya with a protein microarray and ELISA.
http://purl.obolibrary.org/obo/OBI_0003494	Advantage Chikungunya IgM Card kit	http://purl.obolibrary.org/obo/OBI_0003369	assay kit		An assay kit that is manufactured by J. Mitra to detect human IgM antibodies for Chikungunya virus with a protein microarray and double-antigen sandwich ELISA.
http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that detects a type of organism and/or the quantity of individuals of a type of organism.
http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual	http://purl.obolibrary.org/obo/OBI_0002441	physical examination of an organism		A physical examination of an organism's ability to perform functional activities.
http://purl.obolibrary.org/obo/OBI_0003502	facial atrophy assessment	http://purl.obolibrary.org/obo/OBI_0003536	observational assessment of individual		An observational assessment of the loss of facial muscle tissue due to inactivity or disease.
http://purl.obolibrary.org/obo/OBI_0003503	tongue atrophy assessment	http://purl.obolibrary.org/obo/OBI_0003536	observational assessment of individual		An observational assessment of the loss of muscle tissue related to tongue movement due to inactivity or disease.
http://purl.obolibrary.org/obo/OBI_0003504	forced cough assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to cough forcefully.
http://purl.obolibrary.org/obo/OBI_0003505	speech test assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to understandably repeat spoken sentences.
http://purl.obolibrary.org/obo/OBI_0003506	finger to finger assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to touch index fingers together in front of the sternum without oscillation for a specified duration of time
http://purl.obolibrary.org/obo/OBI_0003507	nose to finger assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to touch their own nose and then touch an examiners finger in front of them and then touch their own nose once more.
http://purl.obolibrary.org/obo/OBI_0003508	dysmetria assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to accurately touch a moving target with their finger and then touch their own chin a number of times in a row.
http://purl.obolibrary.org/obo/OBI_0003509	rapid alternating hands assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to alternate the forearm between pronation and suppination as quickly as possible during a specified duration of time
http://purl.obolibrary.org/obo/OBI_0003510	finger taps assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to touch their finger-tip to thumb as many times as possible during a specified duration of time.
http://purl.obolibrary.org/obo/OBI_0003511	heel along shin assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to slide their heel back and forth along their contralateral tibia from the patella to the ankle with the contralateral leg extended.
http://purl.obolibrary.org/obo/OBI_0003512	heel to shin assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to tap their heel to the midpoint of the contralateral shin a number of times.
http://purl.obolibrary.org/obo/OBI_0003513	muscle atrophy assessment	http://purl.obolibrary.org/obo/OBI_0003536	observational assessment of individual		An observational assesment of an individual's muscle tissue loss due to inactivity or disease.
http://purl.obolibrary.org/obo/OBI_0003514	muscle weakness assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to perform muscle movement to overcome gravity or physical resistence.
http://purl.obolibrary.org/obo/OBI_0003515	vibratory sense assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to sense vibration.
http://purl.obolibrary.org/obo/OBI_0003516	position sense assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to sense the position of a finger or toe that has been manipulated by minimal random movements.
http://purl.obolibrary.org/obo/OBI_0003517	deep tendon reflex assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's muscle contraction when a muscle is triggered by a signal from a muscle spindle in response to a stimulus applied to a specific trigger point on the body.
http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		The functional assessment of an individual's ability to maintain balance, posture or upright stability.
http://purl.obolibrary.org/obo/OBI_0003519	sitting posture assessment	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain unsupported posture while sitting over a given time period.
http://purl.obolibrary.org/obo/OBI_0003520	stance feet apart assessment	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet 20 cm apart.
http://purl.obolibrary.org/obo/OBI_0003521	stance feet apart assessment, with eyes closed	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with their eyes closed.
http://purl.obolibrary.org/obo/OBI_0003522	stance feet together assessment	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet together.
http://purl.obolibrary.org/obo/OBI_0003523	stance feet together assessment, with eyes closed	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet together and eyes closed.
http://purl.obolibrary.org/obo/OBI_0003524	tandem stance assessment	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain a stable stance with feet in tandem placement.
http://purl.obolibrary.org/obo/OBI_0003525	stance on one foot assessment	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain a stable stance on one foot.
http://purl.obolibrary.org/obo/OBI_0003526	tandem walk assessment	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's ability to maintain balance while walking in a straight line placing steps in tandem.
http://purl.obolibrary.org/obo/OBI_0003527	gait assessment	http://purl.obolibrary.org/obo/OBI_0003518	limits of stability assessment		A limits of stability assessment designed to assess an individual's manner or pattern of walking.
http://purl.obolibrary.org/obo/OBI_0003528	bulbar assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's lower cranial nerve function via proxy of facial muscle performance.
http://purl.obolibrary.org/obo/OBI_0003529	spontaneous speech assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to articulate spoken words.
http://purl.obolibrary.org/obo/OBI_0003530	limb coordination assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to coordinate limb movement.
http://purl.obolibrary.org/obo/OBI_0003531	upper limb coordination assessment	http://purl.obolibrary.org/obo/OBI_0003530	limb coordination assessment		A limb coordination assessment designed to assess an individual's ability to coordinate upper limb movement.
http://purl.obolibrary.org/obo/OBI_0003532	lower limb coordination assessment	http://purl.obolibrary.org/obo/OBI_0003530	limb coordination assessment		A limb coordination assessment designed to assess an individual's ability to coordinate lower limb movement.
http://purl.obolibrary.org/obo/OBI_0003533	nervous system functionality assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assesment of an individual's nerve performance. Specifically the nerves connecting the sensory and motor structures with the central nervous system.
http://purl.obolibrary.org/obo/OBI_0003534	upright stability assessment	http://purl.obolibrary.org/obo/OBI_0003501	functional assessment of individual		A functional assessment of an individual's ability to maintain upright body posture.
http://purl.obolibrary.org/obo/OBI_0003535	deep tendon reflex assessment of the knee joint	http://purl.obolibrary.org/obo/OBI_0003517	deep tendon reflex assessment		A deep tendon reflex assessment of an individual's reaction to stimulus applied to a knee joint.
http://purl.obolibrary.org/obo/OBI_0003536	observational assessment of individual	http://purl.obolibrary.org/obo/OBI_0002441	physical examination of an organism		A physical examination of an organism through visual assesment.
http://purl.obolibrary.org/obo/OBI_0003537	deep tendon reflex assessment of the ankle joint	http://purl.obolibrary.org/obo/OBI_0003517	deep tendon reflex assessment		A deep tendon reflex assessment of an individual's reaction to stimulus applied to an ankle joint.
http://purl.obolibrary.org/obo/OBI_0003538	deep tendon reflex assessment of the tendon of biceps brachii	http://purl.obolibrary.org/obo/OBI_0003517	deep tendon reflex assessment		A deep tendon reflex assessment of an individual's reaction to stimulus applied to a tendon of biceps brachii.
http://purl.obolibrary.org/obo/OBI_0003539	deep tendon reflex assessment of the brachioradialis	http://purl.obolibrary.org/obo/OBI_0003517	deep tendon reflex assessment		A deep tendon reflex assessment of an individual's reaction to stimulus applied to a brachioradialis.
http://purl.obolibrary.org/obo/OBI_0003540	tandem mass spectrometry assay	http://purl.obolibrary.org/obo/OBI_0000470	mass spectrometry assay		A mass spectrometry assay that uses two or more analyzers separated by a region in which ions can be induced to fragment by transfer of energy (frequently by collision with other molecules).
http://purl.obolibrary.org/obo/OBI_0003541	ELISA measuring Orientia tsutsugamushi IgM antibody	http://purl.obolibrary.org/obo/OBI_0000661	enzyme-linked immunosorbent assay		An enzyme-linked immunosorbent assay that detects the IgM antibody that binds Orientia tsutsugamushi.
http://purl.obolibrary.org/obo/OBI_0003542	microarray assay measuring Dengue IgM antibody	http://purl.obolibrary.org/obo/OBI_0001985	microarray assay		A microarray assay that detects the IgM antibody that binds Dengue.
http://purl.obolibrary.org/obo/OBI_0003543	microarray assay measuring NS1	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		A microarray assay that detects NS1.
http://purl.obolibrary.org/obo/OBI_0003544	analytical chromatography measuring Chikungunya IgM antibody	http://purl.obolibrary.org/obo/OBI_0001630	analytical chromatography		Analytical chromatography that detects the IgM antibody that binds Chikungunya.
http://purl.obolibrary.org/obo/OBI_0003545	ELISA measuring Chikungunya IgM antibody	http://purl.obolibrary.org/obo/OBI_0000661	enzyme-linked immunosorbent assay		An enzyme-linked immunosorbent assay that detects the IgM antibody that binds Chikungunya.
http://purl.obolibrary.org/obo/OBI_0003546	microarray ELISA measuring Chikungunya IgM antibody	http://purl.obolibrary.org/obo/OBI_0000661	enzyme-linked immunosorbent assay		An enzyme-linked immunosorbent assay that uses a microarray as the solid support and detects the IgM antibody that binds Chikungunya.
http://purl.obolibrary.org/obo/OBI_0003652	albumin-free serum	http://purl.obolibrary.org/obo/OBI_0100017	blood serum specimen		A blood serum specimen that contains no albumin.
http://purl.obolibrary.org/obo/OBI_0003653	fasting	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process in which an organism drinks only water and does not eat for a specified period of time.
http://purl.obolibrary.org/obo/OBI_0003689	ice bath	http://purl.obolibrary.org/obo/OBI_0400120	temperature control bath		A temperature control bath in which a water ice mixture acts as contact medium at constant temperature of 0 degrees Celsius or below if salt solutions are used.
http://purl.obolibrary.org/obo/OBI_0003723	natural killer cell percentage assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the percentage of natural killer cells in a specimen.
http://purl.obolibrary.org/obo/OBI_0003724	sperm count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay to count the number of mature sperm in a specimen.
http://purl.obolibrary.org/obo/OBI_0003692	case-control investigation	http://purl.obolibrary.org/obo/OBI_0000066	investigation		An investigation that has participants that bear either a case or control role and which examines the hypothesis that the presence of the outcome in case participants is associated with an exposure that is not associated with control participants.
http://purl.obolibrary.org/obo/OBI_0003696	animal investigation	http://purl.obolibrary.org/obo/OBI_0000066	investigation		An investigation that has non-human animals as its subjects.
http://purl.obolibrary.org/obo/OBI_0003697	clinical investigation	http://purl.obolibrary.org/obo/OBI_0000066	investigation		An investigation on human subjects with the objective to produce information on human health.
http://purl.obolibrary.org/obo/OBI_0003698	observational clinical investigation	http://purl.obolibrary.org/obo/OBI_0003697	clinical investigation		A clinical investigation that does not involve an intervention.
http://purl.obolibrary.org/obo/OBI_0003699	clinical trial	http://purl.obolibrary.org/obo/OBI_0003697	clinical investigation		A clinical investigation that involves an intervention.
http://purl.obolibrary.org/obo/OBI_0003701	phase II clinical trial	http://purl.obolibrary.org/obo/OBI_0003699	clinical trial		A clinical trial that produces information about a drug's effectiveness and short-term adverse events associated with the drug.
http://purl.obolibrary.org/obo/OBI_0003702	phase III clinical trial	http://purl.obolibrary.org/obo/OBI_0003699	clinical trial		A clinical trial that produces information about a drug's safety and effectiveness in different populations, with different dosages, and in combination with other drugs.
http://purl.obolibrary.org/obo/OBI_0003713	organism development assay	http://purl.obolibrary.org/obo/OBI_0002441	physical examination of an organism		A physical examination of an organism that provides information about some developmental process in that organism.
http://purl.obolibrary.org/obo/OBI_0003010	fibrinogen assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures fibrinogen
http://purl.obolibrary.org/obo/OBI_0002554	vagina specimen	http://purl.obolibrary.org/obo/OBI_0001479	specimen from organism		A specimen that is derived from vagina.
http://purl.obolibrary.org/obo/OBI_0002191	courier tracking number	http://purl.obolibrary.org/obo/IAO_0000577	centrally registered identifier symbol		A centrally registered identifier symbol assigned by a courier organization in order to track the delivery of an item.
http://purl.obolibrary.org/obo/OBI_0002192	Leica Peloris rapid tissue processor	http://purl.obolibrary.org/obo/OBI_0001064	automatic tissue processor		An automatic tissue processor that is a dual retort tissue processor manufactured by the Leica company to provide fast, high quality tissue processing for histology laboratories.
http://purl.obolibrary.org/obo/OBI_0002194	Microm Ergostar HM200	http://purl.obolibrary.org/obo/OBI_0400168	microtome		A microtome that is manufactured by Microm and uses a vertical cutting stroke common to all rotary microtomes engaged by a horizontal sliding movement. An operating arm replaces the handwheel and is attached to both sides of the instrument for greater convenience to permit control of sectioning from the left or right.
http://purl.obolibrary.org/obo/OBI_0002195	microtome blade	http://purl.obolibrary.org/obo/OBI_0000968	device		A device that is the part of a microtome used to slice specimens to a desired thickness.
http://purl.obolibrary.org/obo/OBI_0002196	Sakura Low profile Accu-Edge microtome blade	http://purl.obolibrary.org/obo/OBI_0002195	microtome blade		A microtome blade that is manufactured by Feather and is disposable. The ultra-sharp blades section specimens without striations, distortion or chattering.
http://purl.obolibrary.org/obo/OBI_0002197	tissue section thickness	http://purl.obolibrary.org/obo/IAO_0000408	length measurement datum		A length measurement datum that is the result of an assay measuring the thickness of a tissue section.
http://purl.obolibrary.org/obo/OBI_0002199	reason for lack of data item	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that provides an explanation why a data item is not provided.
http://purl.obolibrary.org/obo/OBI_0002201	determination if assay will provide reliable results	http://purl.obolibrary.org/obo/OBI_0000011	planned process		A planned process that is used to assess whether an assay will provide reliable results based on the conditions or qualities of the inputs, devices, and other participants of the assay.
http://purl.obolibrary.org/obo/OBI_0002202	GX	http://purl.obolibrary.org/obo/OBI_0002200	cannot be assessed determination		A cannot be assessed determination for histologic tumor grade.
http://purl.obolibrary.org/obo/OBI_0002203	pTX	http://purl.obolibrary.org/obo/OBI_0002200	cannot be assessed determination		A cannot be assessed determination for pathologic primary tumor staging.
http://purl.obolibrary.org/obo/OBI_0002204	pNX	http://purl.obolibrary.org/obo/OBI_0002200	cannot be assessed determination		A cannot be assessed determination of pathologic staging of lymph nodes.
http://purl.obolibrary.org/obo/OBI_0002205	histologic grade according to AJCC 7th edition	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification		A categorical value specification that is a histologic grade assigned to a tumor slide specimen according to the American Joint Committee on Cancer (AJCC) 7th Edition grading system.
http://purl.obolibrary.org/obo/OBI_0002215	histologic grade for ovarian tumor	http://purl.obolibrary.org/obo/OBI_0001930	categorical value specification		A categorical value specification that is a histologic grade assigned to a ovarian tumor.
http://purl.obolibrary.org/obo/OBI_0002216	histologic grade for ovarian tumor according to a two-tier grading system	http://purl.obolibrary.org/obo/OBI_0002215	histologic grade for ovarian tumor		A histologic grade for ovarian tumor that is from a two-tier histological classification of tumors.
http://purl.obolibrary.org/obo/OBI_0002219	histologic grade for ovarian tumor according to the World Health Organization	http://purl.obolibrary.org/obo/OBI_0002215	histologic grade for ovarian tumor		A histologic grade for ovarian tumor that is from a histological classification by the World Health Organization (WHO).
http://purl.obolibrary.org/obo/OBI_0002368	clinical history of cancer	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history		A clinical history in which there is a diagnosis of cancer.
http://purl.obolibrary.org/obo/OBI_0002370	unknown clinical history of cancer	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history		A clinical history in which it is not known whether there was a diagnosis of cancer.
http://purl.obolibrary.org/obo/OBI_0002373	aunt clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in the female sibling of a parent.
http://purl.obolibrary.org/obo/OBI_0002374	brother clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a male sibling.
http://purl.obolibrary.org/obo/OBI_0002375	daughter clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a person's female child.
http://purl.obolibrary.org/obo/OBI_0002376	father clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a male parent.
http://purl.obolibrary.org/obo/OBI_0002377	mother clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a female parent.
http://purl.obolibrary.org/obo/OBI_0002378	sister clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a female sibling.
http://purl.obolibrary.org/obo/OBI_0002379	son clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a person's male child.
http://purl.obolibrary.org/obo/OBI_0002380	uncle clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a male sibling of a parent.
http://purl.obolibrary.org/obo/OBI_0002381	grandmother clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a female parent of a parent.
http://purl.obolibrary.org/obo/OBI_0002382	grandfather clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a male parent of a parent.
http://purl.obolibrary.org/obo/OBI_0002383	nephew clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a male child of a sibling.
http://purl.obolibrary.org/obo/OBI_0002384	niece clinical history of cancer	http://purl.obolibrary.org/obo/OBI_0002372	family clinical history of cancer		A clinical history in which there is a diagnosis of cancer in a female child of a sibling.
http://purl.obolibrary.org/obo/OBI_0002385	diagnosis of infectious disease	http://purl.obolibrary.org/obo/OGMS_0000073	diagnosis		A diagnosis that is an assertion that a patient who is the subject of a diagnostic process has an infectious disease.
http://purl.obolibrary.org/obo/OBI_0002386	diagnosis of hepatitis B	http://purl.obolibrary.org/obo/OBI_0002385	diagnosis of infectious disease		A diagnosis of infectious disease caused by the hepatitis B virus.
http://purl.obolibrary.org/obo/OBI_0002387	diagnosis of hepatitis C	http://purl.obolibrary.org/obo/OBI_0002385	diagnosis of infectious disease		A diagnosis of infectious disease caused by the hepatitis C virus.
http://purl.obolibrary.org/obo/OBI_0002388	diagnosis of HIV	http://purl.obolibrary.org/obo/OBI_0002385	diagnosis of infectious disease		A diagnosis of infectious disease caused by the human immunodeficiency virus (1 or 2).
http://purl.obolibrary.org/obo/OBI_0002389	clinical history of repeated HIV assays	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history		A clinical history in which there is repeated reactive screening assays for human immunodeficiency virus (1 or 2) antibodies regardless of the results of supplemental assays.
http://purl.obolibrary.org/obo/OBI_0002390	exposure to second hand smoke	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history		A clinical history in which there has been second hand exposure to tobacco smoking.
http://purl.obolibrary.org/obo/OBI_0002391	exposure to second hand smoke in household during childhood	http://purl.obolibrary.org/obo/OBI_0002390	exposure to second hand smoke		An exposure to second hand smoke that occurred in the (patient's) household when the person was a child.
http://purl.obolibrary.org/obo/OBI_0002392	exposure to second hand smoke in current household	http://purl.obolibrary.org/obo/OBI_0002390	exposure to second hand smoke		An exposure to second hand smoke in person's current household.
http://purl.obolibrary.org/obo/OBI_0002393	pregnancy history	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history		A clinical history in which a female has had a pregnancy.
http://purl.obolibrary.org/obo/OBI_0002394	number of pregnancies	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum of the total number of pregnancies a woman has had.
http://purl.obolibrary.org/obo/OBI_0002395	number of live births	http://purl.obolibrary.org/obo/IAO_0000109	measurement datum		A measurement datum of the total number of live births a female has had.
http://purl.obolibrary.org/obo/OBI_0002396	age when gave birth to first child	http://purl.obolibrary.org/obo/OBI_0001167	age measurement datum		An age measurement datum performed on a female when her first biological child was born.
http://purl.obolibrary.org/obo/OBI_0002397	gynecologic surgery history	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history		A clinical history in which a woman has had gynecologic surgery in the past.
http://purl.obolibrary.org/obo/OBI_0002398	hysterectomy history	http://purl.obolibrary.org/obo/OBI_0002397	gynecologic surgery history		A gynecologic surgery history in which a woman has had a hysterectomy.
http://purl.obolibrary.org/obo/OBI_0002399	unilateral oophorectomy history	http://purl.obolibrary.org/obo/OBI_0002397	gynecologic surgery history		A gynecologic surgery history in which a woman has had a unilateral oophorectomy.
http://purl.obolibrary.org/obo/OBI_0002400	neither hysterectomy nor oophorectomy history	http://purl.obolibrary.org/obo/OBI_0002397	gynecologic surgery history		A gynecologic surgery history in which a woman has not had either a hysterectomy or an oophorectomy.
http://purl.obolibrary.org/obo/OBI_0002401	hormonal birth control use history	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that indicates whether a woman has ever used oral contraceptives in order to block ovulation and prevent the occurrence of pregnancy.
http://purl.obolibrary.org/obo/OBI_0002402	hormonal birth control former use history	http://purl.obolibrary.org/obo/OBI_0002401	hormonal birth control use history		A hormonal birth control use history that indicates an individual has previously been a hormonal birth control user but is not a current user.
http://purl.obolibrary.org/obo/OBI_0002403	hormonal birth control current use history	http://purl.obolibrary.org/obo/OBI_0002401	hormonal birth control use history		A hormonal birth control use history that indicates an individual is currently a hormonal birth control user.
http://purl.obolibrary.org/obo/OBI_0002404	no hormonal birth control use history	http://purl.obolibrary.org/obo/OBI_0002401	hormonal birth control use history		A hormonal birth control use history that indicates an individual has not ever been a hormonal birth control user.
http://purl.obolibrary.org/obo/OBI_0002405	hormonal replacement therapy history	http://purl.obolibrary.org/obo/OGMS_0000015	clinical history		A clinical history in which an individual has had hormonal replacement therapy in the past.
http://purl.obolibrary.org/obo/OBI_0002407	pill delivery form for hormonal replacement therapy	http://purl.obolibrary.org/obo/OBI_0002406	delivery form for hormonal replacement therapy		A delivery form for hormonal replacement therapy that is a pill for oral administration.
http://purl.obolibrary.org/obo/OBI_0002408	patch delivery form for hormonal replacement therapy	http://purl.obolibrary.org/obo/OBI_0002406	delivery form for hormonal replacement therapy		A delivery form for hormonal replacement therapy that is a patch for transdermal administration.
http://purl.obolibrary.org/obo/OBI_0002409	cream delivery form for hormonal replacement therapy	http://purl.obolibrary.org/obo/OBI_0002406	delivery form for hormonal replacement therapy		A delivery form for hormonal replacement therapy that is a cream for transdermal administration.
http://purl.obolibrary.org/obo/OBI_0002410	menopausal status	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that indicates the state of a female's cessation of menstruation.
http://purl.obolibrary.org/obo/OBI_0002411	indeterminate menopausal status	http://purl.obolibrary.org/obo/OBI_0002410	menopausal status		A menopausal status that is neither pre- nor post-menopausal.
http://purl.obolibrary.org/obo/OBI_0002412	premenopausal status	http://purl.obolibrary.org/obo/OBI_0002410	menopausal status		A menopausal status indicating that less than 6 months has passed since the last menstrual period and there has not been prior bilateral oophorectomy and not on estrogen replacement.
http://purl.obolibrary.org/obo/OBI_0002413	perimenopausal status	http://purl.obolibrary.org/obo/OBI_0002410	menopausal status		A menopausal status indicating that it has been 6-12 months since last menstrual period.
http://purl.obolibrary.org/obo/OBI_0002414	postmenopausal status	http://purl.obolibrary.org/obo/OBI_0002410	menopausal status		A menopausal status indicating that it has been more than 12 months since the last menstrual period with no prior hysterectomy or that there has been a prior bilateral oophorectomy.
http://purl.obolibrary.org/obo/OBI_0002415	exposure to environmental and workplace carcinogens history	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that indicates the exposure of an individual to carcinogens in the workplace or environment.
http://purl.obolibrary.org/obo/OBI_0002416	exposure to arsenic history	http://purl.obolibrary.org/obo/OBI_0002415	exposure to environmental and workplace carcinogens history		An exposure to environmental and workplace carcinogens history where the carcinogen is arsenic.
http://purl.obolibrary.org/obo/OBI_0002417	exposure to asbestos history	http://purl.obolibrary.org/obo/OBI_0002415	exposure to environmental and workplace carcinogens history		An exposure to environmental and workplace carcinogens history where the carcinogen is asbestos.
http://purl.obolibrary.org/obo/OBI_0002418	exposure to diesel exhaust history	http://purl.obolibrary.org/obo/OBI_0002415	exposure to environmental and workplace carcinogens history		An exposure to environmental and workplace carcinogens history where the carcinogen is diesel exhaust.
http://purl.obolibrary.org/obo/OBI_0002419	exposure to chromium history	http://purl.obolibrary.org/obo/OBI_0002415	exposure to environmental and workplace carcinogens history		An exposure to environmental and workplace carcinogens history where the carcinogen is chromium.
http://purl.obolibrary.org/obo/OBI_0002420	exposure to silica history	http://purl.obolibrary.org/obo/OBI_0002415	exposure to environmental and workplace carcinogens history		An exposure to environmental and workplace carcinogens history where the carcinogen is silica.
http://purl.obolibrary.org/obo/OBI_0002423	age of majority inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that uses the age of majority for a state or institution, where one is generally considered to be an adult, which if met, makes an individual suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002424	chemotherapy treatment exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion that defines whether chemotherapy was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process
http://purl.obolibrary.org/obo/OBI_0002425	radiation treatment exclusion criteria	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion that defines whether radiation was received or is being received for a previous  or current cancer, which when met, makes an individual unsuitable for a given task or participation in a given process
http://purl.obolibrary.org/obo/OBI_0002426	chemotherapy treatment within the recent past exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion that defines whether chemotherapy was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002427	radiation treatment within the recent past exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion that defines whether radiation was received within a certain timeframe, which when met, makes an individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002428	BMI range inclusion criterion	http://purl.obolibrary.org/obo/OBI_0500027	inclusion criterion		An inclusion criterion that defines and states a Body Mass Index range, which if met, makes an individual suitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002429	blood transfusion exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion that is defined by whether the specimen donor received a whole blood transfusion within a specified time frame prior to death, which if met, makes a specimen donor unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002430	history of metastatic cancer exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion defined as whether an individual has ever been diagnosed with metastatic cancer (cancer that spread beyond the initial site such as to other organs like brain bone or liver), which if met, makes the individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002431	intravenous drug use exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion defined as when an individual has a history of intravenous drug abuse for a specific timeframe, which if met, makes the individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002432	history of sex with someone with a history of blood borne infection  exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion defined  as whether an individual has a history of sex with someone who has been diagnosed or at risk for a blood borne infections disease in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002433	history of sex with someone with a history of intravenous drugs exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion defined  as whether an individual has a history of sex with someone who has used intravenous drugs in a specified time frame, which if met, makes the individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002434	HIV exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion defined  as whether an individual has a history of repeatedly reactive screening assays for HIV-1 or HIV-2 antibody regardless of the results of supplemental assays, which if met, makes the individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002435	exposure to blood borne infectious disease exclusion criterion	http://purl.obolibrary.org/obo/OBI_0500028	exclusion criterion		An exclusion criterion defined  as whether an individual has been exposed to a blood borne infections disease through needle sticks and/or contact with non-intact skin and/or contact with open wounds and/or contact with mucous membranes, which if met, makes the individual unsuitable for a given task or participation in a given process.
http://purl.obolibrary.org/obo/OBI_0002436	RNA interactome capture	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that identifies RNA binding proteins by cross-linking RNA and proteins with UV light, then purifying the bound complexes by oligo(dT) capture. Finally, the complexes are analyzed by mass spectrometry.
http://purl.obolibrary.org/obo/OBI_0002438	nuclear ligation assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that detects the proximity of chromosomal DNA through the use of a ligation reaction in isolated nuclei.
http://purl.obolibrary.org/obo/OBI_0002440	Hi-C assay	http://purl.obolibrary.org/obo/OBI_0002439	chromosome conformation capture assay		A chromosome conformation capture assay that detects genome-wide chromosomal interactions. High-throughput techniques are used to sequence the ligated fragments after cross-linking and cutting with restriction enzymes.
http://purl.obolibrary.org/obo/OBI_0002441	physical examination of an organism	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that produces a description of the qualities of an organism that has not been transformed, through observation and physical, non-invasive techniques.
http://purl.obolibrary.org/obo/OBI_0002442	hydroxyl-radical footprinting assay	http://purl.obolibrary.org/obo/OBI_0002162	footprinting assay		A footprinting assay that uses the reaction of hydroxyl radicals with side-chain sites in molecules (proteins, DNA, etc)_ with the resultant mass shift demonstrating the site of modification, used to_ to asses the accessibility of that site.
http://purl.obolibrary.org/obo/OPL_0000267	Plasmodium gametocyte	http://purl.obolibrary.org/obo/NCBITaxon_5820	Plasmodium		A Plasmodium that is located either in the bloodstream of the vertebrate host or midgut of mosquito vector during gametocyte stage. Gametocytes are the precursor cells of the macro- or microgametes
http://purl.obolibrary.org/obo/OBI_0002634	in vivo assay measuring B cell epitope specific disease exacerbation resulting from the adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002677	in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells		An efficacy of B cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0002635	in vivo assay measuring T cell epitope specific disease reduction resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		An efficacy of T cell epitope intervention experiment that detects a decrease in disease after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002636	in vivo assay measuring B cell epitope specific disease reduction resulting from adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002677	in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells		An efficacy of B cell epitope intervention experiment that detects a decrease in disease after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0002637	in vivo assay measuring T cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		An efficacy of T cell epitope intervention experiment that uses a epitope protection experiment after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002638	in vivo assay measuring B cell epitope specific protection from challenge resulting from adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002677	in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells		An efficacy of B cell epitope intervention experiment that uses a epitope protection experiment after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0002639	in vivo assay measuring T cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific T cells based on pathogen burden	http://purl.obolibrary.org/obo/OBI_0003470	in vivo assay measuring T cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring T cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific antibodies or B cells using pathogen burden.
http://purl.obolibrary.org/obo/OBI_0002640	in vivo assay measuring B cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific antibodies or B cells based on pathogen burden	http://purl.obolibrary.org/obo/OBI_0003475	in vivo assay measuring B cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring B cell epitope specific protection from pathogen challenge resulting from the adoptive transfer of epitope specific antibodies or B cells using pathogen burden.
http://purl.obolibrary.org/obo/OBI_0002641	in vivo assay measuring T cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific T cells based on survival	http://purl.obolibrary.org/obo/OBI_0003474	in vivo assay measuring T cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring T cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific T cells using survival.
http://purl.obolibrary.org/obo/OBI_0002642	in vivo assay measuring B cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific antibodies or B cells based on survival	http://purl.obolibrary.org/obo/OBI_0003479	in vivo assay measuring B cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring B cell epitope specific protection from other challenge resulting from the adoptive transfer of epitope specific antibodies or B cells using survival.
http://purl.obolibrary.org/obo/OBI_0002643	in vivo assay measuring T cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific T cells based on tumor burden	http://purl.obolibrary.org/obo/OBI_0003472	in vivo assay measuring T cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific T cells		An in vivo assay measuring T cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific T cells using tumor burden.
http://purl.obolibrary.org/obo/OBI_0002644	in vivo assay measuring B cell epitope specific protection from challenge resulting from the adoptive transfer of epitope specific antibodies or B cells based on tumor burden	http://purl.obolibrary.org/obo/OBI_0003477	in vivo assay measuring B cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific antibodies or B cells		An in vivo assay measuring B cell epitope specific protection from tumor challenge resulting from the adoptive transfer of epitope specific antibodies or B cells using tumor burden.
http://purl.obolibrary.org/obo/OBI_0002645	in vivo assay measuring T cell epitope specific tolerance induction resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		An efficacy of T cell epitope intervention experiment that uses a tolerance induction intervention experiment after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002646	in vivo assay measuring B cell epitope specific tolerance induction resulting from the adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002677	in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells		An efficacy of B cell epitope intervention experiment that uses a tolerance induction intervention experiment after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0002647	Giemsa stain assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		An assay that uses a Giemsa stain to characterize cells.
http://purl.obolibrary.org/obo/OBI_0002648	individual organism specimen	http://purl.obolibrary.org/obo/OBI_0100051	specimen		A specimen composed of an individual organism to be studied in an investigation.
http://purl.obolibrary.org/obo/OBI_0002649	blood microbiology assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that detects microorganisms in a blood specimen.
http://purl.obolibrary.org/obo/OBI_0002664	cytometric bead array assay measuring epitope specific interleukin-15 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-15 production by T cells.
http://purl.obolibrary.org/obo/OBI_0002665	cytometric bead array assay measuring epitope specific interleukin-16 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects interleukin-16 production by T cells.
http://purl.obolibrary.org/obo/OBI_0002666	in vivo assay measuring B cell epitope specific induction of hypersensitivity resulting from the adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0002677	in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells		An efficacy of B cell epitope intervention experiment that detects a hypersensitivity response by monitoring skin reactions after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0002667	in vivo skin test assay measuring T cell epitope specific type IV hypersensitivity resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		An efficacy of T cell epitope intervention experiment that detects epitope specific type IV hypersensitivity after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002668	in vivo assay measuring epitope specific proliferation of T cells resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		A T cell epitope specific proliferation assay that is performed in vivo after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002669	assay measuring epitope specific helper T cell enhancement of a B cell mediated immune response resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance an antibody response after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002670	assay measuring epitope specific helper T cell enhancement of a T cell mediated immune response resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		A T cell epitope specific helper activity assay that detects the ability of a T cell epitope to enhance a T cell response after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002671	in vivo assay measuring epitope specific T cell killing resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		An in vivo cell killing assay that detects the killing of an antigen presenting cell (APC) by a T cell whose TCR recognizes an epitope presented by the APC after adoptive transfer of epitope specific T cells.
http://purl.obolibrary.org/obo/OBI_0002672	ELISA measuring epitope specific perforin release by T cells	http://purl.obolibrary.org/obo/OBI_0001497	assay measuring epitope specific perforin release by T cells		An enzyme-linked immunosorbent assay that detects epitope specific perforin release by T cells.
http://purl.obolibrary.org/obo/OBI_0002674	case series design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design that samples only subjects who have experienced a particular event (outcome or exposure). Such a design, in contrast to a cohort study, does not permit calculation of absolute risk as non-case subjects are not included.
http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0001484	assay measuring T cell epitope specific in vivo activity		An efficacy of T cell epitope intervention experiment that is performed after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002677	in vivo assay measuring a B cell epitope specific response after adoptive transfer of epitope specific antibodies or B cells	http://purl.obolibrary.org/obo/OBI_0001698	assay measuring B cell epitope specific in vivo activity		An efficacy of B cell epitope intervention experiment that is performed after adoptive transfer of epitope specific antibodies or B cells.
http://purl.obolibrary.org/obo/OBI_0002678	in vivo assay measuring T cell epitope specific disease exacerbation resulting from the adoptive transfer of epitope specific T cells	http://purl.obolibrary.org/obo/OBI_0002676	in vivo assay measuring a T cell epitope specific response after adoptive transfer of epitope specific T cells		An efficacy of T cell epitope intervention experiment that uses a disease exacerbation in vivo intervention experiment after adoptive transfer of epitope specfic T cells.
http://purl.obolibrary.org/obo/OBI_0002681	glass bottle	http://purl.obolibrary.org/obo/OBI_0000967	container		A container with a narrow neck that is made of glass.
http://purl.obolibrary.org/obo/OBI_0002682	glass bottle coated with insecticides	http://purl.obolibrary.org/obo/OBI_0002681	glass bottle		A glass bottle that coated with material designed to control insects.
http://purl.obolibrary.org/obo/OBI_0002686	counter current immunoelectrophoresis	http://purl.obolibrary.org/obo/OBI_0600053	electrophoresis		An electrophoresis in which antigen and antibody move in opposite directions and form precipitates in the area between the cells where they meet in concentrations of optimal proportions.
http://purl.obolibrary.org/obo/OBI_0002689	detection of pathogenic organisms objective	http://purl.obolibrary.org/obo/OBI_0000268	organism feature identification objective		An organism feature identification objective that aims to detect whether an organism contains pathogenic organisms.
http://purl.obolibrary.org/obo/OBI_0002690	insecticide resistance detection objective	http://purl.obolibrary.org/obo/OBI_0000268	organism feature identification objective		An organism feature identification objective that aims to detect insecticide resistance of an insect.
http://purl.obolibrary.org/obo/OBI_0002692	polymerase chain reaction assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that uses polymerase chain reaction technique to amplify DNA.
http://purl.obolibrary.org/obo/OBI_0002722	insecticide resistance by ligase detection reaction assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay		An insecticide resistance assay that is based on monitoring known mutations using ligase detection reaction exquisitely discriminate between a mismatched and complementary DNA helix.
http://purl.obolibrary.org/obo/OBI_0002725	insecticide resistance by fluorogenic PCR assay	http://purl.obolibrary.org/obo/OBI_0002696	insecticide resistance by monitoring known mutations assay		An insecticide resistance assay that is based on monitoring known mutations by PCR technique that uses target specific probes labeled with fluorogenic chromophores to detect gene mutation.
http://purl.obolibrary.org/obo/OBI_0002794	reusable patient gown	http://purl.obolibrary.org/obo/OBI_0002792	patient gown		A patient gown intended to be reused after being laundered.
http://purl.obolibrary.org/obo/OBI_0002795	disposable patient gown	http://purl.obolibrary.org/obo/OBI_0002792	patient gown		A patient gown intended for a single period of continuous use and then disposed of.
http://purl.obolibrary.org/obo/OBI_0002797	apron	http://purl.obolibrary.org/obo/OBI_0000968	device		A garment which is worn over other clothing and covers mainly the front of the body.
http://purl.obolibrary.org/obo/OBI_0002798	surgical gown	http://purl.obolibrary.org/obo/OBI_0002796	medical gown		A medical gown which is subjected to a sterilization process and which is intended to be worn by a medical professional during surgical procedures.
http://purl.obolibrary.org/obo/OBI_0002799	personal protective glove	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item		A personal protective device which is a glove.
http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item	http://purl.obolibrary.org/obo/OBI_0002786	personal protective device		A personal protective device which consists of a garment that serves in place of or in addition to regular body clothing.
http://purl.obolibrary.org/obo/OBI_0002803	medical glove	http://purl.obolibrary.org/obo/OBI_0002799	personal protective glove		A personal protective glove which is disposable and is used during medical examinations and procedures to help prevent cross-contamination between caregivers and patients.
http://purl.obolibrary.org/obo/OBI_0002804	nitrile glove	http://purl.obolibrary.org/obo/OBI_0002799	personal protective glove		A personal protective glove which is made out of nitrile rubber.
http://purl.obolibrary.org/obo/OBI_0002807	disposable footwear cover	http://purl.obolibrary.org/obo/OBI_0002806	footwear cover		A footwear cover which is designed for a single period of continuous use and then disposed of.
http://purl.obolibrary.org/obo/OBI_0002808	reusable footwear cover	http://purl.obolibrary.org/obo/OBI_0002806	footwear cover		A footwear cover which is designed for repeated use.
http://purl.obolibrary.org/obo/OBI_0002810	protective coverall	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item		A personal protective clothing item which is a loose fitting coverall for ease of movement, with sleeves, full leggings and often a hood to cover the head. These can also include overshoe pieces to cover footwear and protect against contamination.
http://purl.obolibrary.org/obo/OBI_0002811	protective sleeve	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item		A personal protective clothing item which is a protective cover worn over the arm.
http://purl.obolibrary.org/obo/OBI_0002812	protective apron	http://purl.obolibrary.org/obo/OBI_0002800	personal protective clothing item		A personal protective clothing item which is an apron.
http://purl.obolibrary.org/obo/OBI_0002814	specimen collection device	http://purl.obolibrary.org/obo/OBI_0000968	device		A device used to collect a specimen.
http://purl.obolibrary.org/obo/OBI_0002822	drag swab	http://purl.obolibrary.org/obo/OBI_0002814	specimen collection device		A specimen collection device consisting of a specimen pad made of sterile gauze which is aseptically attached to a pole by clips or to a string
http://purl.obolibrary.org/obo/OBI_0002823	pre-moistened swab stick	http://purl.obolibrary.org/obo/OBI_0002820	specimen collection swab stick		A specimen collection swab stick that is pre-moistened with liquid prior to sampling.
http://purl.obolibrary.org/obo/OBI_0002824	surface wipe	http://purl.obolibrary.org/obo/OBI_0002814	specimen collection device		A sample collection device consisting of a thin, less absorbent sheet, used to collect material from surfaces.
http://purl.obolibrary.org/obo/OBI_0002989	material supplier	http://purl.obolibrary.org/obo/BFO_0000040	material entity		A person or organization that provides material supplies to other people or organizations.
http://purl.obolibrary.org/obo/OBI_0003009	ferritin assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures ferritin
http://purl.obolibrary.org/obo/OBI_0003011	iron assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of iron
http://purl.obolibrary.org/obo/OBI_0003012	ionized calcium assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of ionized calcium
http://purl.obolibrary.org/obo/OBI_0003013	transferrin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of transferrin
http://purl.obolibrary.org/obo/OBI_0003014	uric acid assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of uric acid
http://purl.obolibrary.org/obo/OBI_0003015	globulin assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of globulin
http://purl.obolibrary.org/obo/OBI_0003016	myelocyte assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of myelocytes
http://purl.obolibrary.org/obo/OBI_0003017	metamyelocyte assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of metamyelocytes
http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the proportion of red blood cells
http://purl.obolibrary.org/obo/OBI_0003019	promyelocyte assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of promyelocytes
http://purl.obolibrary.org/obo/OBI_0003021	basophil assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of basophils
http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of neutrophils
http://purl.obolibrary.org/obo/OBI_0003023	eosinophil assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of eosinophils
http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of lymphocytes
http://purl.obolibrary.org/obo/OBI_0003025	monocyte assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of monocytes
http://purl.obolibrary.org/obo/OBI_0003026	reticulocyte assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of reticulocytes
http://purl.obolibrary.org/obo/OBI_0003027	macrophage assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of macrophages
http://purl.obolibrary.org/obo/OBI_0003028	platelet assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the abundance and/or characteristics of platelets
http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of carbon dioxide
http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of sodium(1+)
http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of creatinine
http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of potassium(1+)
http://purl.obolibrary.org/obo/OBI_2100005	basophil count assay	http://purl.obolibrary.org/obo/OBI_0003021	basophil assay		A cytometry assay that measures the count of basophils
http://purl.obolibrary.org/obo/OBI_2100006	neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of neutrophils
http://purl.obolibrary.org/obo/OBI_2100007	eosinophil count assay	http://purl.obolibrary.org/obo/OBI_0003023	eosinophil assay		A cytometry assay that measures the count of eosinophils
http://purl.obolibrary.org/obo/OBI_2100008	lymphocyte count assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A cytometry assay that measures the count of lymphocytes
http://purl.obolibrary.org/obo/OBI_2100009	monocyte count assay	http://purl.obolibrary.org/obo/OBI_0003025	monocyte assay		A cytometry assay that measures the count of monocytes
http://purl.obolibrary.org/obo/OBI_2100010	chloride assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of chloride
http://purl.obolibrary.org/obo/OBI_2100011	erythrocyte count assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the count of erythrocytes
http://purl.obolibrary.org/obo/OBI_2100012	platelet count assay	http://purl.obolibrary.org/obo/OBI_0003028	platelet assay		A cytometry assay that measures the count of platelets
http://purl.obolibrary.org/obo/OBI_2100013	leukocyte count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of leukocytes
http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of hemoglobin
http://purl.obolibrary.org/obo/OBI_2100015	phosphate ion assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of phosphate ion
http://purl.obolibrary.org/obo/OBI_2100016	alanine aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of alanine aminotransferase
http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of alkaline phosphatase (human)
http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of bilirubin IXalpha
http://purl.obolibrary.org/obo/OBI_2100019	aspartate aminotransferase (human) assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of aspartate aminotransferase (human)
http://purl.obolibrary.org/obo/OBI_2100020	glucose assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of glucose
http://purl.obolibrary.org/obo/OBI_2100021	magnesium cation assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of magnesium cation
http://purl.obolibrary.org/obo/OBI_2100022	albumin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of albumin
http://purl.obolibrary.org/obo/OBI_2100023	protein assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of protein
http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay	http://purl.obolibrary.org/obo/OBI_0003012	ionized calcium assay		An analyte assay that measures the abundance of calcium cation
http://purl.obolibrary.org/obo/OBI_2100025	creatine kinase assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of creatine kinase
http://purl.obolibrary.org/obo/OBI_2100026	nucleate erythrocyte count assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the count of nucleate erythrocytes
http://purl.obolibrary.org/obo/OBI_2100027	segmented neutrophil of bone marrow count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of segmented neutrophil of bone marrows
http://purl.obolibrary.org/obo/OBI_2100028	lactate dehydrogenase complex assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures lactate dehydrogenase complex
http://purl.obolibrary.org/obo/OBI_2100029	triglyceride assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of triglyceride
http://purl.obolibrary.org/obo/OBI_2100030	high-density lipoprotein cholesterol assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of high-density lipoprotein cholesterol
http://purl.obolibrary.org/obo/OBI_2100031	cholesterol assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of cholesterol
http://purl.obolibrary.org/obo/OBI_2100032	low-density lipoprotein cholesterol assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of low-density lipoprotein cholesterol
http://purl.obolibrary.org/obo/OBI_2100033	thyroid stimulating hormone assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of thyroid stimulating hormone
http://purl.obolibrary.org/obo/OBI_2100034	prostate-specific antigen assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of prostate-specific antigen
http://purl.obolibrary.org/obo/OBI_2100035	thyroxine assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of thyroxine
http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of elemental oxygen
http://purl.obolibrary.org/obo/OBI_2100037	folic acids assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of folic acids
http://purl.obolibrary.org/obo/OBI_2100038	reticulocyte count assay	http://purl.obolibrary.org/obo/OBI_0003026	reticulocyte assay		A cytometry assay that measures the count of reticulocytes
http://purl.obolibrary.org/obo/OBI_2100039	osmolality assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures osmolality
http://purl.obolibrary.org/obo/OBI_2100040	methemoglobin assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of methemoglobin
http://purl.obolibrary.org/obo/OBI_2100041	cytosolic creatine kinase complex, MB-type assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures cytosolic creatine kinase complex, MB-type
http://purl.obolibrary.org/obo/OBI_2100042	rac-lactic acid assay	http://purl.obolibrary.org/obo/OBI_0000070	assay		An assay that measures rac-lactic acid
http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of hydrogencarbonate
http://purl.obolibrary.org/obo/OBI_2100044	vancomycin assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of vancomycin
http://purl.obolibrary.org/obo/OBI_2100045	tobramycin assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of tobramycin
http://purl.obolibrary.org/obo/OBI_2100046	3,3',5'-triiodothyronine assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of 3,3',5'-triiodothyronine
http://purl.obolibrary.org/obo/OBI_2100047	C-reactive protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of C-reactive protein
http://purl.obolibrary.org/obo/OBI_2100048	megakaryocyte count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of megakaryocytes
http://purl.obolibrary.org/obo/OBI_2100049	mesothelial cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of mesothelial cells
http://purl.obolibrary.org/obo/OBI_2100050	macrophage count assay	http://purl.obolibrary.org/obo/OBI_0003027	macrophage assay		A cytometry assay that measures the count of macrophages
http://purl.obolibrary.org/obo/OBI_2100051	3-hydroxybutyric acid assay	http://purl.obolibrary.org/obo/OBI_0000443	analyte assay		An analyte assay that measures the abundance of 3-hydroxybutyric acid
http://purl.obolibrary.org/obo/OBI_2100052	panel5 venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a panel5 order
http://purl.obolibrary.org/obo/OBI_2100053	panel5 venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a panel5 order
http://purl.obolibrary.org/obo/OBI_2100054	panel5 venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood as part of a panel5 order
http://purl.obolibrary.org/obo/OBI_2100055	panel5 venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a panel5 order
http://purl.obolibrary.org/obo/OBI_2100056	automated differential venous blood basophil count assay	http://purl.obolibrary.org/obo/OBI_0003021	basophil assay		A cytometry assay that measures the count of basophils in venous blood as part of a automated differential order
http://purl.obolibrary.org/obo/OBI_2100057	automated differential venous blood neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of neutrophils in venous blood as part of a automated differential order
http://purl.obolibrary.org/obo/OBI_2100058	automated differential venous blood eosinophil count assay	http://purl.obolibrary.org/obo/OBI_0003023	eosinophil assay		A cytometry assay that measures the count of eosinophils in venous blood as part of a automated differential order
http://purl.obolibrary.org/obo/OBI_2100059	automated differential venous blood lymphocyte count assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A cytometry assay that measures the count of lymphocytes in venous blood as part of a automated differential order
http://purl.obolibrary.org/obo/OBI_2100060	automated differential venous blood monocyte count assay	http://purl.obolibrary.org/obo/OBI_0003025	monocyte assay		A cytometry assay that measures the count of monocytes in venous blood as part of a automated differential order
http://purl.obolibrary.org/obo/OBI_2100061	venous blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in venous blood
http://purl.obolibrary.org/obo/OBI_2100062	CBC with automated differential venous blood RBC count assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the count of RBCs in venous blood as part of a CBC with automated differential order
http://purl.obolibrary.org/obo/OBI_2100063	CBC with automated differential venous blood platelet count assay	http://purl.obolibrary.org/obo/OBI_0003028	platelet assay		A cytometry assay that measures the count of platelets in venous blood as part of a CBC with automated differential order
http://purl.obolibrary.org/obo/OBI_2100064	CBC with automated differential venous blood WBC count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of WBCs in venous blood as part of a CBC with automated differential order
http://purl.obolibrary.org/obo/OBI_2100065	CBC with automated differential venous blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in venous blood as part of a CBC with automated differential order
http://purl.obolibrary.org/obo/OBI_2100066	CBC with automated differential venous blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in venous blood as part of a CBC with automated differential order
http://purl.obolibrary.org/obo/OBI_2100067	venous blood phosphate assay	http://purl.obolibrary.org/obo/OBI_2100015	phosphate ion assay		An analyte assay that measures the abundance of phosphate in venous blood
http://purl.obolibrary.org/obo/OBI_2100068	liver injury venous blood alanine aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100016	alanine aminotransferase assay		An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver injury order
http://purl.obolibrary.org/obo/OBI_2100069	liver injury venous blood human alkaline phosphatase assay	http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay		An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a liver injury order
http://purl.obolibrary.org/obo/OBI_2100070	liver injury venous blood bilirubin assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		An analyte assay that measures the abundance of bilirubin in venous blood as part of a liver injury order
http://purl.obolibrary.org/obo/OBI_2100071	liver injury venous blood human aspartate aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100019	aspartate aminotransferase (human) assay		An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver injury order
http://purl.obolibrary.org/obo/OBI_2100072	venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood
http://purl.obolibrary.org/obo/OBI_2100073	venous blood magnesium assay	http://purl.obolibrary.org/obo/OBI_2100021	magnesium cation assay		An analyte assay that measures the abundance of magnesium in venous blood
http://purl.obolibrary.org/obo/OBI_2100074	CBC venous blood RBC count assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the count of RBCs in venous blood as part of a CBC order
http://purl.obolibrary.org/obo/OBI_2100075	CBC venous blood WBC count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of WBCs in venous blood as part of a CBC order
http://purl.obolibrary.org/obo/OBI_2100076	CBC venous blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in venous blood as part of a CBC order
http://purl.obolibrary.org/obo/OBI_2100077	CBC venous blood platelet count assay	http://purl.obolibrary.org/obo/OBI_0003028	platelet assay		A cytometry assay that measures the count of platelets in venous blood as part of a CBC order
http://purl.obolibrary.org/obo/OBI_2100078	CBC venous blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in venous blood as part of a CBC order
http://purl.obolibrary.org/obo/OBI_2100079	corrected venous blood leukocyte count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of leukocytes in venous blood as part of a corrected order
http://purl.obolibrary.org/obo/OBI_2100080	liver evaluation venous blood bilirubin assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		An analyte assay that measures the abundance of bilirubin in venous blood as part of a liver evaluation order
http://purl.obolibrary.org/obo/OBI_2100081	liver evaluation venous blood globulin assay	http://purl.obolibrary.org/obo/OBI_0003015	globulin assay		An analyte assay that measures the abundance of globulin in venous blood as part of a liver evaluation order
http://purl.obolibrary.org/obo/OBI_2100082	liver evaluation venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a liver evaluation order
http://purl.obolibrary.org/obo/OBI_2100083	liver evaluation venous blood human aspartate aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100019	aspartate aminotransferase (human) assay		An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver evaluation order
http://purl.obolibrary.org/obo/OBI_2100084	liver evaluation venous blood alanine aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100016	alanine aminotransferase assay		An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver evaluation order
http://purl.obolibrary.org/obo/OBI_2100085	liver evaluation venous blood human alkaline phosphatase assay	http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay		An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a liver evaluation order
http://purl.obolibrary.org/obo/OBI_2100086	liver evaluation venous blood protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in venous blood as part of a liver evaluation order
http://purl.obolibrary.org/obo/OBI_2100087	basic metabolic panel venous blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in venous blood as part of a basic metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100088	basic metabolic panel venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a basic metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100089	basic metabolic panel venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a basic metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100090	basic metabolic panel venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood as part of a basic metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100091	basic metabolic panel venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood as part of a basic metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100092	basic metabolic panel venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood as part of a basic metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100093	basic metabolic panel venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a basic metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100094	venous blood creatine kinase assay	http://purl.obolibrary.org/obo/OBI_2100025	creatine kinase assay		An analyte assay that measures the abundance of creatine kinase in venous blood
http://purl.obolibrary.org/obo/OBI_2100095	venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood
http://purl.obolibrary.org/obo/OBI_2100096	venous blood ferritin assay	http://purl.obolibrary.org/obo/OBI_0003009	ferritin assay		An assay that measures ferritin in venous blood
http://purl.obolibrary.org/obo/OBI_2100097	total venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood as part of a total order
http://purl.obolibrary.org/obo/OBI_2100098	venous blood iron assay	http://purl.obolibrary.org/obo/OBI_0003011	iron assay		An analyte assay that measures the abundance of iron in venous blood
http://purl.obolibrary.org/obo/OBI_2100099	CBC with manual differential venous blood band neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of band neutrophils in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100100	CBC with manual differential venous blood WBC count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of WBCs in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100101	CBC with manual differential venous blood eosinophil count assay	http://purl.obolibrary.org/obo/OBI_0003023	eosinophil assay		A cytometry assay that measures the count of eosinophils in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100102	CBC with manual differential venous blood lymphocyte count assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A cytometry assay that measures the count of lymphocytes in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100103	CBC with manual differential venous blood nucleated RBC count assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the count of nucleated RBCs in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100104	CBC with manual differential venous blood monocyte count assay	http://purl.obolibrary.org/obo/OBI_0003025	monocyte assay		A cytometry assay that measures the count of monocytes in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100105	CBC with manual differential venous blood segmented neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of segmented neutrophils in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100106	CBC with manual differential venous blood basophil count assay	http://purl.obolibrary.org/obo/OBI_0003021	basophil assay		A cytometry assay that measures the count of basophils in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100107	venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood
http://purl.obolibrary.org/obo/OBI_2100108	cardiac enzymes venous blood creatine kinase assay	http://purl.obolibrary.org/obo/OBI_2100025	creatine kinase assay		An analyte assay that measures the abundance of creatine kinase in venous blood as part of a cardiac enzymes order
http://purl.obolibrary.org/obo/OBI_2100109	venous blood haptoglobin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of haptoglobin in venous blood
http://purl.obolibrary.org/obo/OBI_2100110	venous blood lactate dehydrogenase assay	http://purl.obolibrary.org/obo/OBI_2100028	lactate dehydrogenase complex assay		An assay that measures lactate dehydrogenase in venous blood
http://purl.obolibrary.org/obo/OBI_2100111	venous blood prealbunin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of prealbunin in venous blood
http://purl.obolibrary.org/obo/OBI_2100112	lipid panel venous blood triglyceride assay	http://purl.obolibrary.org/obo/OBI_2100029	triglyceride assay		An analyte assay that measures the abundance of triglyceride in venous blood as part of a lipid panel order
http://purl.obolibrary.org/obo/OBI_2100113	lipid panel venous blood high density lipoprotein assay	http://purl.obolibrary.org/obo/OBI_2100030	high-density lipoprotein cholesterol assay		An analyte assay that measures the abundance of high density lipoprotein in venous blood as part of a lipid panel order
http://purl.obolibrary.org/obo/OBI_2100114	lipid panel venous blood cholesterol assay	http://purl.obolibrary.org/obo/OBI_2100031	cholesterol assay		An analyte assay that measures the abundance of cholesterol in venous blood as part of a lipid panel order
http://purl.obolibrary.org/obo/OBI_2100115	lipid panel venous blood low density lipoprotein assay	http://purl.obolibrary.org/obo/OBI_2100032	low-density lipoprotein cholesterol assay		An analyte assay that measures the abundance of low density lipoprotein in venous blood as part of a lipid panel order
http://purl.obolibrary.org/obo/OBI_2100116	venous blood hemoglobin A1c assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures hemoglobin A1c in venous blood
http://purl.obolibrary.org/obo/OBI_2100117	venous blood uric acid assay	http://purl.obolibrary.org/obo/OBI_0003014	uric acid assay		An analyte assay that measures the abundance of uric acid in venous blood
http://purl.obolibrary.org/obo/OBI_2100118	total venous blood protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in venous blood as part of a total order
http://purl.obolibrary.org/obo/OBI_2100119	venous blood thyroid stimulating hormone assay	http://purl.obolibrary.org/obo/OBI_2100033	thyroid stimulating hormone assay		An analyte assay that measures the abundance of thyroid stimulating hormone in venous blood
http://purl.obolibrary.org/obo/OBI_2100120	venous blood prostate specific antigen assay	http://purl.obolibrary.org/obo/OBI_2100034	prostate-specific antigen assay		An analyte assay that measures the abundance of prostate specific antigen in venous blood
http://purl.obolibrary.org/obo/OBI_2100121	24 hour total urine volume assay	http://purl.obolibrary.org/obo/OBI_0003043	urine assay		An assay that measures volume in urine as part of a 24 hour total order
http://purl.obolibrary.org/obo/OBI_2100122	T4 uptake venous blood T4 assay	http://purl.obolibrary.org/obo/OBI_2100035	thyroxine assay		An analyte assay that measures the abundance of T4 in venous blood as part of a T4 uptake order
http://purl.obolibrary.org/obo/OBI_2100123	arterial blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in arterial blood
http://purl.obolibrary.org/obo/OBI_2100124	CBC with manual differential venous blood cell count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of cells in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100125	hemoglobin oxygen saturation arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a hemoglobin oxygen saturation order
http://purl.obolibrary.org/obo/OBI_2100126	hemoglobin oxygen saturation arterial blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a hemoglobin oxygen saturation order
http://purl.obolibrary.org/obo/OBI_2100127	inpatient profile venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a inpatient profile order
http://purl.obolibrary.org/obo/OBI_2100128	inpatient profile venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood as part of a inpatient profile order
http://purl.obolibrary.org/obo/OBI_2100129	inpatient profile venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a inpatient profile order
http://purl.obolibrary.org/obo/OBI_2100130	inpatient profile venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a inpatient profile order
http://purl.obolibrary.org/obo/OBI_2100131	venous blood folic acid assay	http://purl.obolibrary.org/obo/OBI_2100037	folic acids assay		An analyte assay that measures the abundance of folic acid in venous blood
http://purl.obolibrary.org/obo/OBI_2100132	count venous blood reticulocyte count assay	http://purl.obolibrary.org/obo/OBI_0003026	reticulocyte assay		A cytometry assay that measures the count of reticulocytes in venous blood as part of a count order
http://purl.obolibrary.org/obo/OBI_2100133	venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood
http://purl.obolibrary.org/obo/OBI_2100134	venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood
http://purl.obolibrary.org/obo/OBI_2100135	venous blood transferrin assay	http://purl.obolibrary.org/obo/OBI_0003013	transferrin assay		An analyte assay that measures the abundance of transferrin in venous blood
http://purl.obolibrary.org/obo/OBI_2100136	venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood
http://purl.obolibrary.org/obo/OBI_2100137	random electrolytes urine sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in urine as part of a random electrolytes order
http://purl.obolibrary.org/obo/OBI_2100138	random electrolytes urine potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in urine as part of a random electrolytes order
http://purl.obolibrary.org/obo/OBI_2100139	urine creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in urine
http://purl.obolibrary.org/obo/OBI_2100140	urine osmolality assay	http://purl.obolibrary.org/obo/OBI_2100039	osmolality assay		An assay that measures osmolality in urine
http://purl.obolibrary.org/obo/OBI_2100141	cooximitery arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a cooximitery order
http://purl.obolibrary.org/obo/OBI_2100142	cooximitery arterial blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a cooximitery order
http://purl.obolibrary.org/obo/OBI_2100143	cooximitery arterial blood methemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100040	methemoglobin assay		An analyte assay that measures the abundance of methemoglobin in arterial blood as part of a cooximitery order
http://purl.obolibrary.org/obo/OBI_2100144	electrolytes urine sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in urine as part of a electrolytes order
http://purl.obolibrary.org/obo/OBI_2100145	electrolytes urine potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in urine as part of a electrolytes order
http://purl.obolibrary.org/obo/OBI_2100146	Biosite cardiac panel arterial blood creatine kinase MB assay	http://purl.obolibrary.org/obo/OBI_2100041	cytosolic creatine kinase complex, MB-type assay		An assay that measures creatine kinase MB in arterial blood as part of a Biosite cardiac panel order
http://purl.obolibrary.org/obo/OBI_2100147	venous blood fibrinogen assay	http://purl.obolibrary.org/obo/OBI_0003010	fibrinogen assay		An assay that measures fibrinogen in venous blood
http://purl.obolibrary.org/obo/OBI_2100148	comprehensive metabolic panel venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100149	comprehensive metabolic panel venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100150	comprehensive metabolic panel venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100151	comprehensive metabolic panel venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100152	comprehensive metabolic panel venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100153	comprehensive metabolic panel venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100154	comprehensive metabolic panel venous blood human alkaline phosphatase assay	http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay		An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100155	comprehensive metabolic panel venous blood bilirubin assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		An analyte assay that measures the abundance of bilirubin in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100156	comprehensive metabolic panel venous blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100157	comprehensive metabolic panel venous blood human aspartate aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100019	aspartate aminotransferase (human) assay		An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100158	comprehensive metabolic panel venous blood protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100159	comprehensive metabolic panel venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100160	comprehensive metabolic panel venous blood alanine aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100016	alanine aminotransferase assay		An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a comprehensive metabolic panel order
http://purl.obolibrary.org/obo/OBI_2100161	venous blood LDH assay	http://purl.obolibrary.org/obo/OBI_2100028	lactate dehydrogenase complex assay		An assay that measures LDH in venous blood
http://purl.obolibrary.org/obo/OBI_2100162	venous blood creatine kinase MB assay	http://purl.obolibrary.org/obo/OBI_2100041	cytosolic creatine kinase complex, MB-type assay		An assay that measures creatine kinase MB in venous blood
http://purl.obolibrary.org/obo/OBI_2100163	venous blood lactic acid assay	http://purl.obolibrary.org/obo/OBI_2100042	rac-lactic acid assay		An assay that measures lactic acid in venous blood
http://purl.obolibrary.org/obo/OBI_2100164	venous blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in venous blood
http://purl.obolibrary.org/obo/OBI_2100165	venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood
http://purl.obolibrary.org/obo/OBI_2100166	blood gas venous blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in venous blood as part of a blood gas order
http://purl.obolibrary.org/obo/OBI_2100167	ionized venous blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in venous blood as part of a ionized order
http://purl.obolibrary.org/obo/OBI_2100168	blood gas venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a blood gas order
http://purl.obolibrary.org/obo/OBI_2100169	blood gas venous blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in venous blood as part of a blood gas order
http://purl.obolibrary.org/obo/OBI_2100170	arterial blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in arterial blood
http://purl.obolibrary.org/obo/OBI_2100171	venous blood tacrolimus assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of tacrolimus in venous blood
http://purl.obolibrary.org/obo/OBI_2100172	random venous blood vancomycin assay	http://purl.obolibrary.org/obo/OBI_2100044	vancomycin assay		An analyte assay that measures the abundance of vancomycin in venous blood as part of a random order
http://purl.obolibrary.org/obo/OBI_2100173	venous blood mycophenolic acid assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of mycophenolic acid in venous blood
http://purl.obolibrary.org/obo/OBI_2100174	non-vented blood gas arterial blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a non-vented blood gas order
http://purl.obolibrary.org/obo/OBI_2100175	non-vented blood gas arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a non-vented blood gas order
http://purl.obolibrary.org/obo/OBI_2100176	non-vented blood gas arterial blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a non-vented blood gas order
http://purl.obolibrary.org/obo/OBI_2100177	quantitative venous blood IgG assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures IgG in venous blood as part of a quantitative order
http://purl.obolibrary.org/obo/OBI_2100178	quantitative venous blood IgM assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures IgM in venous blood as part of a quantitative order
http://purl.obolibrary.org/obo/OBI_2100179	quantitative venous blood IgA assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures IgA in venous blood as part of a quantitative order
http://purl.obolibrary.org/obo/OBI_2100180	arterial blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in arterial blood
http://purl.obolibrary.org/obo/OBI_2100181	arterial blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in arterial blood
http://purl.obolibrary.org/obo/OBI_2100182	ionized arterial blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in arterial blood as part of a ionized order
http://purl.obolibrary.org/obo/OBI_2100183	vented blood gas arterial blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a vented blood gas order
http://purl.obolibrary.org/obo/OBI_2100184	vented blood gas arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a vented blood gas order
http://purl.obolibrary.org/obo/OBI_2100185	vented blood gas arterial blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a vented blood gas order
http://purl.obolibrary.org/obo/OBI_2100186	arterial blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in arterial blood
http://purl.obolibrary.org/obo/OBI_2100187	arterial blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in arterial blood
http://purl.obolibrary.org/obo/OBI_2100188	arterial blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in arterial blood
http://purl.obolibrary.org/obo/OBI_2100189	GEM premier blood gas venous blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100190	GEM premier blood gas venous blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100191	GEM premier blood gas venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100192	GEM premier blood gas venous blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100193	GEM premier blood gas venous blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100194	GEM premier blood gas venous blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100195	GEM premier blood gas venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100196	GEM premier blood gas venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100197	GEM premier blood gas venous blood lactic acid assay	http://purl.obolibrary.org/obo/OBI_2100042	rac-lactic acid assay		An assay that measures lactic acid in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100198	GEM premier blood gas venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a GEM premier blood gas order
http://purl.obolibrary.org/obo/OBI_2100199	trough venous blood tobramycin assay	http://purl.obolibrary.org/obo/OBI_2100045	tobramycin assay		An analyte assay that measures the abundance of tobramycin in venous blood as part of a trough order
http://purl.obolibrary.org/obo/OBI_2100200	random venous blood tobramycin assay	http://purl.obolibrary.org/obo/OBI_2100045	tobramycin assay		An analyte assay that measures the abundance of tobramycin in venous blood as part of a random order
http://purl.obolibrary.org/obo/OBI_2100201	CBC with manual differential venous blood metamyelocyte count assay	http://purl.obolibrary.org/obo/OBI_0003017	metamyelocyte assay		A cytometry assay that measures the count of metamyelocytes in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100202	arterial blood lactic acid assay	http://purl.obolibrary.org/obo/OBI_2100042	rac-lactic acid assay		An assay that measures lactic acid in arterial blood
http://purl.obolibrary.org/obo/OBI_2100203	venous blood 25-hydroxyvitamin D2 assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of 25-hydroxyvitamin D2 in venous blood
http://purl.obolibrary.org/obo/OBI_2100204	venous blood digoxin assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of digoxin in venous blood
http://purl.obolibrary.org/obo/OBI_2100205	urine protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in urine
http://purl.obolibrary.org/obo/OBI_2100206	venous blood tobramycin assay	http://purl.obolibrary.org/obo/OBI_2100045	tobramycin assay		An analyte assay that measures the abundance of tobramycin in venous blood
http://purl.obolibrary.org/obo/OBI_2100207	CBC with manual differential venous blood myelocyte count assay	http://purl.obolibrary.org/obo/OBI_0003165	myelocyte count assay		A cytometry assay that measures the count of myelocytes in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100208	SPEP protein electrophoresis venous blood beta-globin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of beta-globin in venous blood as part of a SPEP protein electrophoresis order
http://purl.obolibrary.org/obo/OBI_2100209	SPEP protein electrophoresis venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a SPEP protein electrophoresis order
http://purl.obolibrary.org/obo/OBI_2100210	SPEP protein electrophoresis venous blood protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in venous blood as part of a SPEP protein electrophoresis order
http://purl.obolibrary.org/obo/OBI_2100211	trough venous blood vancomycin assay	http://purl.obolibrary.org/obo/OBI_2100044	vancomycin assay		An analyte assay that measures the abundance of vancomycin in venous blood as part of a trough order
http://purl.obolibrary.org/obo/OBI_2100212	hepatic panel venous blood protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in venous blood as part of a hepatic panel order
http://purl.obolibrary.org/obo/OBI_2100213	hepatic panel venous blood bilirubin assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		An analyte assay that measures the abundance of bilirubin in venous blood as part of a hepatic panel order
http://purl.obolibrary.org/obo/OBI_2100214	hepatic panel venous blood alanine aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100016	alanine aminotransferase assay		An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a hepatic panel order
http://purl.obolibrary.org/obo/OBI_2100215	hepatic panel venous blood human aspartate aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100019	aspartate aminotransferase (human) assay		An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a hepatic panel order
http://purl.obolibrary.org/obo/OBI_2100216	hepatic panel venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a hepatic panel order
http://purl.obolibrary.org/obo/OBI_2100217	hepatic panel venous blood human alkaline phosphatase assay	http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay		An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a hepatic panel order
http://purl.obolibrary.org/obo/OBI_2100218	estimated venous blood glomerular filtration assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures glomerular filtration in venous blood as part of a estimated order
http://purl.obolibrary.org/obo/OBI_2100219	DT60 venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood as part of a DT60 order
http://purl.obolibrary.org/obo/OBI_2100220	fasting venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood as part of a fasting order
http://purl.obolibrary.org/obo/OBI_2100221	random venous blood amikacin assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of amikacin in venous blood as part of a random order
http://purl.obolibrary.org/obo/OBI_2100222	venous blood ammonia assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of ammonia in venous blood
http://purl.obolibrary.org/obo/OBI_2100223	venous blood GGT assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of GGT in venous blood
http://purl.obolibrary.org/obo/OBI_2100224	chem11 venous blood phosphate assay	http://purl.obolibrary.org/obo/OBI_2100015	phosphate ion assay		An analyte assay that measures the abundance of phosphate in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100225	chem11 venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100226	chem11 venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100227	chem11 venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100228	chem11 venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100229	chem11 venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100230	chem11 venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100231	chem11 venous blood magnesium assay	http://purl.obolibrary.org/obo/OBI_2100021	magnesium cation assay		An analyte assay that measures the abundance of magnesium in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100232	chem11 venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100233	chem11 venous blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in venous blood as part of a chem11 order
http://purl.obolibrary.org/obo/OBI_2100234	total venous blood IgE assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures IgE in venous blood as part of a total order
http://purl.obolibrary.org/obo/OBI_2100235	chem16 venous blood human aspartate aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100019	aspartate aminotransferase (human) assay		An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100236	chem16 venous blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100237	chem16 venous blood magnesium assay	http://purl.obolibrary.org/obo/OBI_2100021	magnesium cation assay		An analyte assay that measures the abundance of magnesium in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100238	chem16 venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100239	chem16 venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100240	chem16 venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100241	chem16 venous blood triglyceride assay	http://purl.obolibrary.org/obo/OBI_2100029	triglyceride assay		An analyte assay that measures the abundance of triglyceride in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100242	chem16 venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100243	chem16 venous blood phosphate assay	http://purl.obolibrary.org/obo/OBI_2100015	phosphate ion assay		An analyte assay that measures the abundance of phosphate in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100244	chem16 venous blood human alkaline phosphatase assay	http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay		An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100245	chem16 venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100246	chem16 venous blood bilirubin assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		An analyte assay that measures the abundance of bilirubin in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100247	chem16 venous blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100248	chem16 venous blood alanine aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100016	alanine aminotransferase assay		An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100249	chem16 venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a chem16 order
http://purl.obolibrary.org/obo/OBI_2100250	POC chem8 arterial blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in arterial blood as part of a POC chem8 order
http://purl.obolibrary.org/obo/OBI_2100251	POC chem8 arterial blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a POC chem8 order
http://purl.obolibrary.org/obo/OBI_2100252	POC chem8 arterial blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in arterial blood as part of a POC chem8 order
http://purl.obolibrary.org/obo/OBI_2100253	POC chem8 arterial blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in arterial blood as part of a POC chem8 order
http://purl.obolibrary.org/obo/OBI_2100254	POC chem8 arterial blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in arterial blood as part of a POC chem8 order
http://purl.obolibrary.org/obo/OBI_2100255	POC chem8 arterial blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a POC chem8 order
http://purl.obolibrary.org/obo/OBI_2100256	POC chem8 arterial blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in arterial blood as part of a POC chem8 order
http://purl.obolibrary.org/obo/OBI_2100257	peak venous blood tobramycin assay	http://purl.obolibrary.org/obo/OBI_2100045	tobramycin assay		An analyte assay that measures the abundance of tobramycin in venous blood as part of a peak order
http://purl.obolibrary.org/obo/OBI_2100258	24 hour urine creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in urine as part of a 24 hour order
http://purl.obolibrary.org/obo/OBI_2100259	intact venous blood PTH assay	http://purl.obolibrary.org/obo/OBI_2100034	prostate-specific antigen assay		An analyte assay that measures the abundance of PTH in venous blood as part of a intact order
http://purl.obolibrary.org/obo/OBI_2100260	total venous blood PSA assay	http://purl.obolibrary.org/obo/OBI_2100034	prostate-specific antigen assay		An analyte assay that measures the abundance of PSA in venous blood as part of a total order
http://purl.obolibrary.org/obo/OBI_2100261	total venous blood T3 assay	http://purl.obolibrary.org/obo/OBI_2100046	3,3',5'-triiodothyronine assay		An analyte assay that measures the abundance of T3 in venous blood as part of a total order
http://purl.obolibrary.org/obo/OBI_2100262	24 hour urine protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in urine as part of a 24 hour order
http://purl.obolibrary.org/obo/OBI_2100263	total venous blood cholesterol assay	http://purl.obolibrary.org/obo/OBI_2100031	cholesterol assay		An analyte assay that measures the abundance of cholesterol in venous blood as part of a total order
http://purl.obolibrary.org/obo/OBI_2100264	venous blood triglyceride assay	http://purl.obolibrary.org/obo/OBI_2100029	triglyceride assay		An analyte assay that measures the abundance of triglyceride in venous blood
http://purl.obolibrary.org/obo/OBI_2100265	tube 4 count cerebrospinal fluid cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of cells in cerebrospinal fluid as part of a tube 4 count order
http://purl.obolibrary.org/obo/OBI_2100266	cerebrospinal fluid protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100267	cerebrospinal fluid glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100268	tube 1 count cerebrospinal fluid cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of cells in cerebrospinal fluid as part of a tube 1 count order
http://purl.obolibrary.org/obo/OBI_2100269	venous blood dehydroepiandrosterone assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of dehydroepiandrosterone in venous blood
http://purl.obolibrary.org/obo/OBI_2100270	venous blood cortisol assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of cortisol in venous blood
http://purl.obolibrary.org/obo/OBI_2100271	ABL90 panel arterial blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100272	ABL90 panel arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100273	ABL90 panel arterial blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100274	ABL90 panel arterial blood lactic acid assay	http://purl.obolibrary.org/obo/OBI_2100042	rac-lactic acid assay		An assay that measures lactic acid in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100275	ABL90 panel arterial blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100276	ABL90 panel arterial blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100277	ABL90 panel arterial blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100278	ABL90 panel arterial blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100279	ABL90 panel arterial blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100280	ABL90 panel arterial blood temperature assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures temperature in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100281	ABL90 panel arterial blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100282	ABL90 panel arterial blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100283	CBC with manual differential venous blood promyelocyte count assay	http://purl.obolibrary.org/obo/OBI_0003019	promyelocyte assay		A cytometry assay that measures the count of promyelocytes in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100284	ABL90 panel venous blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100285	ABL90 panel venous blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100286	ABL90 panel venous blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100287	ABL90 panel venous blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100288	ABL90 panel venous blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100289	ABL90 panel venous blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100290	ABL90 panel venous blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100291	ABL90 panel venous blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100292	ABL90 panel venous blood lactic acid assay	http://purl.obolibrary.org/obo/OBI_2100042	rac-lactic acid assay		An assay that measures lactic acid in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100293	ABL90 panel venous blood chloride assay	http://purl.obolibrary.org/obo/OBI_2100010	chloride assay		An analyte assay that measures the abundance of chloride in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100294	venous blood T4 assay	http://purl.obolibrary.org/obo/OBI_2100035	thyroxine assay		An analyte assay that measures the abundance of T4 in venous blood
http://purl.obolibrary.org/obo/OBI_2100295	free venous blood T4 assay	http://purl.obolibrary.org/obo/OBI_2100035	thyroxine assay		An analyte assay that measures the abundance of T4 in venous blood as part of a free order
http://purl.obolibrary.org/obo/OBI_2100296	ABL90 panel venous blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100297	urine sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in urine
http://purl.obolibrary.org/obo/OBI_2100298	bone profile venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a bone profile order
http://purl.obolibrary.org/obo/OBI_2100299	bone profile venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood as part of a bone profile order
http://purl.obolibrary.org/obo/OBI_2100300	bone profile venous blood human alkaline phosphatase assay	http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay		An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a bone profile order
http://purl.obolibrary.org/obo/OBI_2100301	bone profile venous blood protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in venous blood as part of a bone profile order
http://purl.obolibrary.org/obo/OBI_2100302	bone profile venous blood phosphate assay	http://purl.obolibrary.org/obo/OBI_2100015	phosphate ion assay		An analyte assay that measures the abundance of phosphate in venous blood as part of a bone profile order
http://purl.obolibrary.org/obo/OBI_2100303	ABG/electrolytes arterial blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a ABG/electrolytes order
http://purl.obolibrary.org/obo/OBI_2100304	ABG/electrolytes arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a ABG/electrolytes order
http://purl.obolibrary.org/obo/OBI_2100305	ABG/electrolytes arterial blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a ABG/electrolytes order
http://purl.obolibrary.org/obo/OBI_2100306	CBC with automated differential venous blood nucleated RBC count assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the count of nucleated RBCs in venous blood as part of a CBC with automated differential order
http://purl.obolibrary.org/obo/OBI_2100307	ABL90 panel venous blood methemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100040	methemoglobin assay		An analyte assay that measures the abundance of methemoglobin in venous blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100308	ABL90 panel arterial blood methemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100040	methemoglobin assay		An analyte assay that measures the abundance of methemoglobin in arterial blood as part of a ABL90 panel order
http://purl.obolibrary.org/obo/OBI_2100309	venous blood valproic acid assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of valproic acid in venous blood
http://purl.obolibrary.org/obo/OBI_2100310	high sensitivity cardiac/neonatal venous blood c-reactive protein assay	http://purl.obolibrary.org/obo/OBI_2100047	C-reactive protein assay		An analyte assay that measures the abundance of c-reactive protein in venous blood as part of a high sensitivity cardiac/neonatal order
http://purl.obolibrary.org/obo/OBI_2100311	POC arterial blood creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in arterial blood as part of a POC order
http://purl.obolibrary.org/obo/OBI_2100312	GEM4000 ANLCOOX arterial blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100313	GEM4000 ANLCOOX arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100314	GEM4000 ANLCOOX arterial blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100315	GEM4000 ANLCOOX arterial blood temperature assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures temperature in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100316	GEM4000 ANLCOOX arterial blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100317	GEM4000 ANLCOOX arterial blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100318	GEM4000 ANLCOOX arterial blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100319	GEM4000 ANLCOOX arterial blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100320	GEM4000 ANLCOOX arterial blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100321	GEM4000 ANLCOOX arterial blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in arterial blood as part of a GEM4000 ANLCOOX order
http://purl.obolibrary.org/obo/OBI_2100322	ionized venous blood calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of calcium in venous blood as part of a ionized order
http://purl.obolibrary.org/obo/OBI_2100323	venous blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in venous blood
http://purl.obolibrary.org/obo/OBI_2100324	CBC with manual differential venous blood megakaryocyte count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of megakaryocytes in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100325	non-cardiac venous blood c-reactive protein assay	http://purl.obolibrary.org/obo/OBI_2100047	C-reactive protein assay		An analyte assay that measures the abundance of c-reactive protein in venous blood as part of a non-cardiac order
http://purl.obolibrary.org/obo/OBI_2100326	intraoperative venous blood PTH assay	http://purl.obolibrary.org/obo/OBI_2100034	prostate-specific antigen assay		An analyte assay that measures the abundance of PTH in venous blood as part of a intraoperative order
http://purl.obolibrary.org/obo/OBI_2100327	venous blood parathyroid hormone assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of parathyroid hormone in venous blood
http://purl.obolibrary.org/obo/OBI_2100328	total bodily fluid protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in bodily fluid as part of a total order
http://purl.obolibrary.org/obo/OBI_2100329	bodily fluid glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in bodily fluid
http://purl.obolibrary.org/obo/OBI_2100330	count bodily fluid cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of cells in bodily fluid as part of a count order
http://purl.obolibrary.org/obo/OBI_2100331	manual differential bodily fluid segmented neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of segmented neutrophils in bodily fluid as part of a manual differential order
http://purl.obolibrary.org/obo/OBI_2100332	manual differential bodily fluid mesothelial cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of mesothelial cells in bodily fluid as part of a manual differential order
http://purl.obolibrary.org/obo/OBI_2100333	manual differential bodily fluid monocyte count assay	http://purl.obolibrary.org/obo/OBI_0003025	monocyte assay		A cytometry assay that measures the count of monocytes in bodily fluid as part of a manual differential order
http://purl.obolibrary.org/obo/OBI_2100334	manual differential bodily fluid lymphocyte count assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A cytometry assay that measures the count of lymphocytes in bodily fluid as part of a manual differential order
http://purl.obolibrary.org/obo/OBI_2100335	manual differential bodily fluid macrophage count assay	http://purl.obolibrary.org/obo/OBI_0003027	macrophage assay		A cytometry assay that measures the count of macrophages in bodily fluid as part of a manual differential order
http://purl.obolibrary.org/obo/OBI_2100336	manual differential bodily fluid basophil count assay	http://purl.obolibrary.org/obo/OBI_0003021	basophil assay		A cytometry assay that measures the count of basophils in bodily fluid as part of a manual differential order
http://purl.obolibrary.org/obo/OBI_2100337	manual differential bodily fluid eosinophil count assay	http://purl.obolibrary.org/obo/OBI_0003023	eosinophil assay		A cytometry assay that measures the count of eosinophils in bodily fluid as part of a manual differential order
http://purl.obolibrary.org/obo/OBI_2100338	liver function venous blood bilirubin assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		An analyte assay that measures the abundance of bilirubin in venous blood as part of a liver function order
http://purl.obolibrary.org/obo/OBI_2100339	liver function venous blood alanine aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100016	alanine aminotransferase assay		An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver function order
http://purl.obolibrary.org/obo/OBI_2100340	liver function venous blood human aspartate aminotransferase assay	http://purl.obolibrary.org/obo/OBI_2100019	aspartate aminotransferase (human) assay		An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver function order
http://purl.obolibrary.org/obo/OBI_2100341	liver function venous blood albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in venous blood as part of a liver function order
http://purl.obolibrary.org/obo/OBI_2100342	liver function venous blood protein assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of protein in venous blood as part of a liver function order
http://purl.obolibrary.org/obo/OBI_2100343	liver function venous blood human alkaline phosphatase assay	http://purl.obolibrary.org/obo/OBI_2100017	alkaline phosphatase (human) assay		An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a liver function order
http://purl.obolibrary.org/obo/OBI_2100344	vitamin B12 and Folate venous blood folic acid assay	http://purl.obolibrary.org/obo/OBI_2100037	folic acids assay		An analyte assay that measures the abundance of folic acid in venous blood as part of a vitamin B12 and Folate order
http://purl.obolibrary.org/obo/OBI_2100345	bodily fluid cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of cells in bodily fluid
http://purl.obolibrary.org/obo/OBI_2100346	venous blood reticulocyte count assay	http://purl.obolibrary.org/obo/OBI_0003026	reticulocyte assay		A cytometry assay that measures the count of reticulocytes in venous blood
http://purl.obolibrary.org/obo/OBI_2100347	bodily fluid cholesterol assay	http://purl.obolibrary.org/obo/OBI_2100031	cholesterol assay		An analyte assay that measures the abundance of cholesterol in bodily fluid
http://purl.obolibrary.org/obo/OBI_2100348	TSH reflex Free T4 venous blood thyroid stimulating hormone assay	http://purl.obolibrary.org/obo/OBI_2100033	thyroid stimulating hormone assay		An analyte assay that measures the abundance of thyroid stimulating hormone in venous blood as part of a TSH reflex Free T4 order
http://purl.obolibrary.org/obo/OBI_2100349	direct venous blood bilirubin assay	http://purl.obolibrary.org/obo/OBI_2100018	bilirubin IXalpha assay		An analyte assay that measures the abundance of bilirubin in venous blood as part of a direct order
http://purl.obolibrary.org/obo/OBI_2100350	free venous blood T3 assay	http://purl.obolibrary.org/obo/OBI_2100046	3,3',5'-triiodothyronine assay		An analyte assay that measures the abundance of T3 in venous blood as part of a free order
http://purl.obolibrary.org/obo/OBI_2100351	bodily fluid albumin assay	http://purl.obolibrary.org/obo/OBI_2100022	albumin assay		An analyte assay that measures the abundance of albumin in bodily fluid
http://purl.obolibrary.org/obo/OBI_2100352	bodily fluid triglyceride assay	http://purl.obolibrary.org/obo/OBI_2100029	triglyceride assay		An analyte assay that measures the abundance of triglyceride in bodily fluid
http://purl.obolibrary.org/obo/OBI_2100353	hemoglobin and hematocrit venous blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in venous blood as part of a hemoglobin and hematocrit order
http://purl.obolibrary.org/obo/OBI_2100354	hemoglobin and hematocrit venous blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in venous blood as part of a hemoglobin and hematocrit order
http://purl.obolibrary.org/obo/OBI_2100355	venous blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in venous blood
http://purl.obolibrary.org/obo/OBI_2100356	venous blood temperature assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures temperature in venous blood
http://purl.obolibrary.org/obo/OBI_2100357	venous blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in venous blood
http://purl.obolibrary.org/obo/OBI_2100358	venous blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in venous blood
http://purl.obolibrary.org/obo/OBI_2100359	venous blood osmolality assay	http://purl.obolibrary.org/obo/OBI_2100039	osmolality assay		An assay that measures osmolality in venous blood
http://purl.obolibrary.org/obo/OBI_2100360	liver fibrosis (chronic viral hepatitis) venous blood platelet count assay	http://purl.obolibrary.org/obo/OBI_0003028	platelet assay		A cytometry assay that measures the count of platelets in venous blood as part of a liver fibrosis (chronic viral hepatitis) order
http://purl.obolibrary.org/obo/OBI_2100361	venous blood T3 assay	http://purl.obolibrary.org/obo/OBI_2100046	3,3',5'-triiodothyronine assay		An analyte assay that measures the abundance of T3 in venous blood
http://purl.obolibrary.org/obo/OBI_2100362	CBC with manual differential venous blood neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of neutrophils in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100363	creatinine clearance urine creatinine assay	http://purl.obolibrary.org/obo/OBI_2100003	creatinine assay		An analyte assay that measures the abundance of creatinine in urine as part of a creatinine clearance order
http://purl.obolibrary.org/obo/OBI_2100364	venous blood beta hydroxybutryic acid assay	http://purl.obolibrary.org/obo/OBI_2100051	3-hydroxybutyric acid assay		An analyte assay that measures the abundance of beta hydroxybutryic acid in venous blood
http://purl.obolibrary.org/obo/OBI_2100365	venous blood megakaryocyte count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of megakaryocytes in venous blood
http://purl.obolibrary.org/obo/OBI_2100366	venous blood nucleated RBC count assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the count of nucleated RBCs in venous blood
http://purl.obolibrary.org/obo/OBI_2100367	venous blood WBC count assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		A cytometry assay that measures the count of WBCs in venous blood
http://purl.obolibrary.org/obo/OBI_2100368	automated count venous blood reticulocyte count assay	http://purl.obolibrary.org/obo/OBI_0003026	reticulocyte assay		A cytometry assay that measures the count of reticulocytes in venous blood as part of a automated count order
http://purl.obolibrary.org/obo/OBI_2100369	total venous blood homocysteine assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An analyte assay that measures the abundance of homocysteine in venous blood as part of a total order
http://purl.obolibrary.org/obo/OBI_2100370	venous blood Ceruloplasmin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of Ceruloplasmin in venous blood
http://purl.obolibrary.org/obo/OBI_2100371	GEM4 arterial blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100372	GEM4 arterial blood lactic acid assay	http://purl.obolibrary.org/obo/OBI_2100042	rac-lactic acid assay		An assay that measures lactic acid in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100373	GEM4 arterial blood hemoglobin assay	http://purl.obolibrary.org/obo/OBI_2100014	hemoglobin assay		An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100374	GEM4 arterial blood sodium assay	http://purl.obolibrary.org/obo/OBI_2100002	sodium(1+) assay		An analyte assay that measures the abundance of sodium in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100375	GEM4 arterial blood potassium assay	http://purl.obolibrary.org/obo/OBI_2100004	potassium(1+) assay		An analyte assay that measures the abundance of potassium in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100376	GEM4 arterial blood temperature assay	http://purl.obolibrary.org/obo/OBI_0003040	blood assay		An assay that measures temperature in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100377	GEM4 arterial blood glucose assay	http://purl.obolibrary.org/obo/OBI_2100020	glucose assay		An analyte assay that measures the abundance of glucose in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100378	GEM4 arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100379	GEM4 arterial blood hematocrit assay	http://purl.obolibrary.org/obo/OBI_0003018	hematocrit assay		A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100380	GEM4 arterial blood ionized calcium assay	http://purl.obolibrary.org/obo/OBI_2100024	calcium cation assay		An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100381	GEM4 arterial blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a GEM4 order
http://purl.obolibrary.org/obo/OBI_2100382	liver fibrosis (NAFLD) venous blood platelet count assay	http://purl.obolibrary.org/obo/OBI_0003028	platelet assay		A cytometry assay that measures the count of platelets in venous blood as part of a liver fibrosis (NAFLD) order
http://purl.obolibrary.org/obo/OBI_2100383	venous blood beta hydroxybutric acid assay	http://purl.obolibrary.org/obo/OBI_2100051	3-hydroxybutyric acid assay		An analyte assay that measures the abundance of beta hydroxybutric acid in venous blood
http://purl.obolibrary.org/obo/OBI_2100384	CBC with manual differential venous blood plasma cell count assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A cytometry assay that measures the count of plasma cells in venous blood as part of a CBC with manual differential order
http://purl.obolibrary.org/obo/OBI_2100385	venous blood erythropoietin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of erythropoietin in venous blood
http://purl.obolibrary.org/obo/OBI_2100386	blood gas arterial blood oxygen assay	http://purl.obolibrary.org/obo/OBI_2100036	elemental oxygen assay		An analyte assay that measures the abundance of oxygen in arterial blood as part of a blood gas order
http://purl.obolibrary.org/obo/OBI_2100387	blood gas arterial blood bicarbonate assay	http://purl.obolibrary.org/obo/OBI_2100043	hydrogencarbonate assay		An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a blood gas order
http://purl.obolibrary.org/obo/OBI_2100388	blood gas arterial blood carbon dioxide assay	http://purl.obolibrary.org/obo/OBI_2100001	carbon dioxide assay		An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a blood gas order
http://purl.obolibrary.org/obo/OBI_2100389	free/total venous blood PSA assay	http://purl.obolibrary.org/obo/OBI_2100034	prostate-specific antigen assay		An analyte assay that measures the abundance of PSA in venous blood as part of a free/total order
http://purl.obolibrary.org/obo/OBI_2100390	cerebrospinal fluid lymphocyte count assay	http://purl.obolibrary.org/obo/OBI_0003024	lymphocyte assay		A cytometry assay that measures the count of lymphocytes in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100391	cerebrospinal fluid segmented neutrophil count assay	http://purl.obolibrary.org/obo/OBI_0003022	neutrophil assay		A cytometry assay that measures the count of segmented neutrophils in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100392	cerebrospinal fluid mesothelial cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay that measures the count of mesothelial cells in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100393	cerebrospinal fluid macrophage count assay	http://purl.obolibrary.org/obo/OBI_0003027	macrophage assay		A cytometry assay that measures the count of macrophages in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100394	cerebrospinal fluid basophil count assay	http://purl.obolibrary.org/obo/OBI_0003021	basophil assay		A cytometry assay that measures the count of basophils in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100395	cerebrospinal fluid monocyte count assay	http://purl.obolibrary.org/obo/OBI_0003025	monocyte assay		A cytometry assay that measures the count of monocytes in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100396	cerebrospinal fluid eosinophil count assay	http://purl.obolibrary.org/obo/OBI_0003023	eosinophil assay		A cytometry assay that measures the count of eosinophils in cerebrospinal fluid
http://purl.obolibrary.org/obo/OBI_2100397	venous blood beta-2-microglobulin assay	http://purl.obolibrary.org/obo/OBI_2100023	protein assay		An analyte assay that measures the abundance of beta-2-microglobulin in venous blood
http://purl.obolibrary.org/obo/OBI_2100398	lipid panel reflex direct venous blood low density lipoprotein assay	http://purl.obolibrary.org/obo/OBI_2100032	low-density lipoprotein cholesterol assay		An analyte assay that measures the abundance of low density lipoprotein in venous blood as part of a Lipid panel reflex direct order
http://purl.obolibrary.org/obo/OBI_2100399	lipid panel reflex direct venous blood triglyceride assay	http://purl.obolibrary.org/obo/OBI_2100029	triglyceride assay		An analyte assay that measures the abundance of triglyceride in venous blood as part of a Lipid panel reflex direct order
http://purl.obolibrary.org/obo/OBI_2100400	lipid panel reflex direct venous blood cholesterol assay	http://purl.obolibrary.org/obo/OBI_2100031	cholesterol assay		An analyte assay that measures the abundance of cholesterol in venous blood as part of a Lipid panel reflex direct order
http://purl.obolibrary.org/obo/OBI_2100401	lipid panel reflex direct venous blood high density lipoprotein assay	http://purl.obolibrary.org/obo/OBI_2100030	high-density lipoprotein cholesterol assay		An analyte assay that measures the abundance of high density lipoprotein in venous blood as part of a Lipid panel reflex direct order
http://purl.obolibrary.org/obo/OBI_0003149	basophil percentage assay	http://purl.obolibrary.org/obo/OBI_0003021	basophil assay		A basophil assay that measures the percentage of basophils in a specimen.
http://purl.obolibrary.org/obo/OBI_0003384	synaptosome preparation process	http://purl.obolibrary.org/obo/OBI_0600014	material component separation		A material component separation process where a synaptic terminal is isolated from a neuron by mild homogenization of nervous tissue under isotonic conditions and subsequent fractionation using differential and density gradient centrifugation.
http://purl.obolibrary.org/obo/PR_000085778	modified histone	http://purl.obolibrary.org/obo/PR_000000001	protein		A histone that contains one or more amino acid modifications.
http://purl.obolibrary.org/obo/OBI_0003722	natural killer cell count assay	http://purl.obolibrary.org/obo/OBI_0001977	cytometry assay		A cytometry assay to determine the number of natural killer cells in a specimen
http://purl.obolibrary.org/obo/OBI_0003714	reproductive assay	http://purl.obolibrary.org/obo/OBI_0002441	physical examination of an organism		A physical examination of an organism that provides information about some reproductive process in that organism.
http://purl.obolibrary.org/obo/OBI_0003127	B cell epitope assay	http://purl.obolibrary.org/obo/OBI_1110128	immune epitope assay		An immune epitope assay that characterizes the structrue of an antibody-epitope complex, or measures the binding of an antibody receptor to epitope, or the immune response process resulting from such a binding event or the recognition of the epitope.
http://purl.obolibrary.org/obo/OBI_0003116	antibody detection by cytometric bead array assay	http://purl.obolibrary.org/obo/OBI_0000920	cytometric bead array assay		A cytometric bead array assay that detects antigen-specific antibodies. In the assay a series of beads are coated with antigens which capture antibodies specific to the antigens. Fluorescent labeled secondary antibodies are used to detect the antibodies of interest.
http://purl.obolibrary.org/obo/OBI_0003709	assessment of learning and/or memory response in an organism	http://purl.obolibrary.org/obo/OBI_0003533	nervous system functionality assessment		A nervous system functionality assessment of learning or memory in an organism
http://purl.obolibrary.org/obo/OBI_0002133	cytometric bead array assay measuring  epitope specific chemokine (C-C motif) ligand 20 production by T cells	http://purl.obolibrary.org/obo/OBI_0003115	antigen detection by cytometric bead array assay		A cytometric bead array assay that detects chemokine (C-C motif) ligand 20 production by T cells.
http://purl.obolibrary.org/obo/OBI_0002123	IHC slide staining	http://purl.obolibrary.org/obo/OBI_0302887	staining		A staining using labeled antibodies, i.e. the analytical part of immunohistochemistry. The staining is applied to fixed specimens on slides to identify biomarkers in tissues.
http://purl.obolibrary.org/obo/OBI_0002124	H&E slide staining	http://purl.obolibrary.org/obo/OBI_0302887	staining		A staining using hematoxylin and eosin. The staining is applied to fixed specimens on slides to observe the whole structure and morphology of cells in a tissue; nuclei are stained dark blue/purple while cytoplasm is stained pink.
http://purl.obolibrary.org/obo/OBI_0002125	H&E-stained fixed tissue slide specimen	http://purl.obolibrary.org/obo/OMIABIS_0000052	fixed tissue slide specimen		A fixed tissue slide specimen that is the output of H&E slide staining.
http://purl.obolibrary.org/obo/OBI_0002126	IHC-stained fixed tissue slide specimen	http://purl.obolibrary.org/obo/OMIABIS_0000052	fixed tissue slide specimen		A fixed tissue slide specimen that is the output of immunohistochemistry slide staining.
http://purl.obolibrary.org/obo/OBI_0002127	single cell specimen	http://purl.obolibrary.org/obo/OBI_0001468	cell specimen		A cell specimen that contains only one cell.
http://purl.obolibrary.org/obo/OBI_0002130	Illumina Infinium Omni5Exome-4 Kit	http://purl.obolibrary.org/obo/OBI_0001869	Illumina BeadChip		An Illumina BeadChip which is an array that interrogates over 4.3 million whole-genome variants for genotyping and copy number variation.
http://purl.obolibrary.org/obo/OBI_0002131	Illumina Infinium MethylationEPIC v1.0 BeadChip	http://purl.obolibrary.org/obo/OBI_0001870	Illumina methylation BeadChip		An Illumina methylation BeadChip which is an array that interrogates ~ 850,000 methylation sites per sample at single-nucleotide resolution.
http://purl.obolibrary.org/obo/OBI_0002591	colocalization identification design	http://purl.obolibrary.org/obo/OBI_0002590	molecular interaction identification design		A molecular interaction identification design that investigates the co-occurence and correlation of two or more molecules.
http://purl.obolibrary.org/obo/OBI_0002592	genetic interaction identification design	http://purl.obolibrary.org/obo/OBI_0002590	molecular interaction identification design		A molecular interaction identification design that investigates a phenotype that is the result of two or more genetic perturbations, and is not explained by the individual genetic perturbations alone.
http://purl.obolibrary.org/obo/OBI_0002593	functional association identification design	http://purl.obolibrary.org/obo/OBI_0002590	molecular interaction identification design		A molecular interaction identification design that investigates a relationship that is the result of intermediate steps between two or more molecules that are not necessarily in direct contact with each other.
http://purl.obolibrary.org/obo/OBI_0002595	enzymatic reaction identification design	http://purl.obolibrary.org/obo/OBI_0002594	direct interaction identification design		A direct interaction identification design that investigations a biological reaction on a molecule which has been triggered by an enzyme.
http://purl.obolibrary.org/obo/OBI_0002596	self interaction identification design	http://purl.obolibrary.org/obo/OBI_0002590	molecular interaction identification design		A molecular interaction identification design that investigates intra-molecular interactions between two or more regions of a single molecule.
http://purl.obolibrary.org/obo/OBI_0002599	swab specimen	http://purl.obolibrary.org/obo/OBI_0100051	specimen		A specimen that is stored on a swab as the output of a collecting specimen with swab process.
http://purl.obolibrary.org/obo/OBI_0002600	collecting specimen with swab	http://purl.obolibrary.org/obo/OBI_0000659	specimen collection process		A specimen collection process that uses a swab as the collection device. A swab is an absorbent material (e.g. cotton) on a rod (e.g., wooden stick).
http://purl.obolibrary.org/obo/OBI_0002601	demultiplexed sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		Sequence data in which an identifier subsequence has been used to categorize each reads by source.
http://purl.obolibrary.org/obo/OBI_0002602	multiplexed sequence data	http://purl.obolibrary.org/obo/OBI_0000973	sequence data		Sequence data from a sequence library generated from at least two different sources, where each read in the sequence data includes base calls from a multiplex identifier sequence that can be used to trace the source of the read to its source.
http://purl.obolibrary.org/obo/OBI_0002603	areolar swab specimen	http://purl.obolibrary.org/obo/OBI_0002604	breast swab specimen		A specimen that is collected with a swab from the surface of an areola of a breast.
http://purl.obolibrary.org/obo/OBI_0002604	breast swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen that is collected with a swab from the surface of a breast.
http://purl.obolibrary.org/obo/OBI_0002605	cheek swab specimen	http://purl.obolibrary.org/obo/OBI_0002607	oral swab specimen		A specimen that is collected with a swab from the cheek portion of the inside surface of a mouth.
http://purl.obolibrary.org/obo/OBI_0002606	nasopharyngeal swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen that is collected with a swab from the surface of a nasopharynx.
http://purl.obolibrary.org/obo/OBI_0002607	oral swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen that is collected with a swab from the inside surface of a mouth.
http://purl.obolibrary.org/obo/OBI_0002608	oropharyngeal swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen that is collected with a swab from the surface of a oropharynx.
http://purl.obolibrary.org/obo/OBI_0002609	rectal swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen that is collected with a swab from the surface of a rectum.
http://purl.obolibrary.org/obo/OBI_0002610	tongue swab specimen	http://purl.obolibrary.org/obo/OBI_0002607	oral swab specimen		A specimen that is collected with a swab from the surface of a tongue.
http://purl.obolibrary.org/obo/OBI_0002611	vagina swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen that is collected with a swab from the surface of a vagina.
http://purl.obolibrary.org/obo/OBI_0002613	environmental swab specimen	http://purl.obolibrary.org/obo/OBI_0002599	swab specimen		A specimen that is collected with a swab from the surface of an environmenal material.
http://purl.obolibrary.org/obo/OBI_0002489	differential medium assay	http://purl.obolibrary.org/obo/OBI_0003498	organism detection assay		An organism detection assay that uses a differential medium to achieve its objective.
http://purl.obolibrary.org/obo/OBI_0002614	birth cohort study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A cohort study design for which the subjects are followed from the time of birth usually including information about gestation and follow up.
http://purl.obolibrary.org/obo/OBI_0002615	disease specific study design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design for which material and information is collected from subjects that have already developed a particular disease.
http://purl.obolibrary.org/obo/OBI_0002616	genealogical record	http://purl.obolibrary.org/obo/IAO_0000310	document		A document about the family relationships of persons related as members of a domestic group linked through descent from a common ancestor, marriage, or adoption.
http://purl.obolibrary.org/obo/OBI_0002617	national registry	http://purl.obolibrary.org/obo/IAO_0000030	information content entity		An information content entity that contains information about a nationwide group of individuals.
http://purl.obolibrary.org/obo/OBI_0002618	national biomedical registry	http://purl.obolibrary.org/obo/OBI_0002617	national registry		A national registry that contains information about individuals that was accumulated for a biomedical purpose, such as diagnoses, treatments, or outcomes.
http://purl.obolibrary.org/obo/OBI_0002983	altitude measurement datum	http://purl.obolibrary.org/obo/IAO_0000408	length measurement datum		A length measurement datum between a point at sea or ground level and some point above it.
http://purl.obolibrary.org/obo/OBI_0003074	common name of organism	http://purl.obolibrary.org/obo/IAO_0000300	textual entity		A textual entity refers to a taxon or organism that is based on the normal language of everyday life; this kind of name is often contrasted with the scientific name for the same organism, which is Latinized.
http://purl.obolibrary.org/obo/OBI_0003412	linked-read sequencing assay	http://purl.obolibrary.org/obo/OBI_0000626	DNA sequencing assay		A DNA sequencing assay that uses microfluidics to partition and barcode high molecular weight DNA such that short reads derived from fragments of the large piece of DNA can be assembled within the context of the high molecular weight piece of DNA they are derived from, facilitating the use of short read data to sequence and assemble large genomes.
http://purl.obolibrary.org/obo/OBI_0003690	dry ice bath	http://purl.obolibrary.org/obo/OBI_0400120	temperature control bath		A temperature control bath in which a dry ice solvent mixture acts as contact medium at a constant temperatures significantly below 0 degrees Celsius.
http://purl.obolibrary.org/obo/OGMS_0000123	clinical data item	http://purl.obolibrary.org/obo/IAO_0000027	data item		A data item that is about a patient and is the specified output of a health care process assay or diagnostic process
http://purl.obolibrary.org/obo/OBI_0002779	mid-turbinate nasal swab specimen	http://purl.obolibrary.org/obo/OBI_0000917	nasal swab specimen		A specimen that is collected with a mid-turbinate nasal swab from the turbinate area of the nasal cavity.
http://purl.obolibrary.org/obo/OBI_0002782	obsolete_upper respiratory specimen	http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class		A specimen that is derived from the upper respiratory tract
http://purl.obolibrary.org/obo/OBI_0002783	lower respiratory tract specimen	http://purl.obolibrary.org/obo/OBI_2000005	respiratory system specimen		A specimen that is derived from the lower respiratory tract.
http://purl.obolibrary.org/obo/OBI_0002784	anterior nasal swab specimen	http://purl.obolibrary.org/obo/OBI_0000917	nasal swab specimen		A specimen that is derived from the anterior nasal wall
http://purl.obolibrary.org/obo/OBI_0002897	surveillance process	http://purl.obolibrary.org/obo/OBI_0000066	investigation		An investigation in which some entity is monitored, and data concerning that entity collected, interpreted, and disseminated, for the purpose of managing, directing, or protecting that entity, or some other entity.
http://purl.obolibrary.org/obo/OBI_0002901	visible light source	http://purl.obolibrary.org/obo/OBI_0400065	light source		A light source that provides visible light for use in a distant area using a delivery system.
http://purl.obolibrary.org/obo/OBI_0002902	solar light source	http://purl.obolibrary.org/obo/OBI_0400065	light source		A light source that light is produced from solar energy.
http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap	http://purl.obolibrary.org/obo/OBI_0000968	device		A device designed to catch arthropods.
http://purl.obolibrary.org/obo/OBI_0002921	artificial pit shelter	http://purl.obolibrary.org/obo/OBI_0002939	resting arthropod trap		An arthropod trap, consisting of a pit dug in the ground to provide a space for arthropods to rest and be collected.
http://purl.obolibrary.org/obo/OBI_0002922	baited net trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap designed to work with an animal (which could be human) inside a netted structure. This structure is designed so that an arthropod, attracted by the animal, can fly into the netted structure but can neither escape nor reach the animal.
http://purl.obolibrary.org/obo/OBI_0002923	barrier trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap consisting of a static physical barrier designed to funnel arthropods in flight into a container.
http://purl.obolibrary.org/obo/OBI_0002924	BG-Counter	http://purl.obolibrary.org/obo/OBI_0000968	device		A device manufactured by BioGents that is designed to count mosquitoes passing through the device, differentiating the mosquitoes from other arthropods.
http://purl.obolibrary.org/obo/OBI_0002925	BG-Sentinel trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that is manufactured by Biogents and is designed to attract arthropods through the use of a motorized fan to mimic convection currents produced by a human. The current also pulls arthropods into the trap, where a layer of gauze prevents the arthropods from escaping along with the air current.
http://purl.obolibrary.org/obo/OBI_0002929	gravid trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that is designed to collect gravid female arthropods or their eggs.
http://purl.obolibrary.org/obo/OBI_0002933	Mosquito Magnet Pro trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that is powered by propane and is designed to emit a combination of carbon dioxide, heat, water, and oct-1-en-3-ol attractants while simultaneously using suction to trap arthropods.
http://purl.obolibrary.org/obo/OBI_0002934	MosquiTRAP	http://purl.obolibrary.org/obo/OBI_0002929	gravid trap		A gravid trap consisting of an arthropod attractant and adhesive surface.
http://purl.obolibrary.org/obo/OBI_0002939	resting arthropod trap	http://purl.obolibrary.org/obo/OBI_0002920	arthropod trap		An arthropod trap that is designed to be attractive to an arthropod as a place to rest during a period of inactivity.
http://purl.obolibrary.org/obo/OBI_0002945	population based design	http://purl.obolibrary.org/obo/OBI_0500000	study design		A study design where the selection of the individuals that are included into the study are intended to be representative of all individuals in the a priori defined specific population and is done at the population level or among the population groups, generally to find the cause, incidence or spread of the disease or to see the response to the treatment, nutrition or environment.
http://purl.obolibrary.org/obo/OBI_0002971	endotracheal tube specimen	http://purl.obolibrary.org/obo/OBI_0002783	lower respiratory tract specimen		A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected upon removal of the tube from the trachea.
http://purl.obolibrary.org/obo/OBI_0002972	endotracheal aspirate specimen	http://purl.obolibrary.org/obo/OBI_0002781	lower respiratory tract aspirate specimen		A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected by suction without removing the tube.
http://purl.obolibrary.org/obo/OBI_0002996	blood meal source role	http://purl.obolibrary.org/obo/BFO_0000023	role		A role borne by an organism that is gained during a process in which another organism ingests blood as food from the organism.
http://purl.obolibrary.org/obo/OBI_0003072	axillary temperature measurement datum	http://purl.obolibrary.org/obo/OBI_0003079	temperature measurement datum		A temperature measurement datum that is about an axilla.
http://purl.obolibrary.org/obo/OBI_0003073	organismal body temperature measurement datum	http://purl.obolibrary.org/obo/OBI_0003079	temperature measurement datum		A temperature measurement datum that is about an organism.
http://purl.obolibrary.org/obo/OBI_0003717	heart rate variability assay	http://purl.obolibrary.org/obo/OBI_0003718	pulse rate assay		A pulse rate assay that measures beat to beat variability in heart beats.
http://purl.obolibrary.org/obo/IAO_8000000	ontology module	http://purl.obolibrary.org/obo/IAO_0000102	data about an ontology part	ontology file	
http://purl.obolibrary.org/obo/NCBITaxon_2732406	Kitrinoviricota	http://purl.obolibrary.org/obo/NCBITaxon_2559587	Riboviria	Tombus-Noda-like virus sp.	
http://purl.obolibrary.org/obo/IAO_8000017	ontology module subsetted by expressivity	http://purl.obolibrary.org/obo/IAO_8000006	subset ontology module		
http://purl.obolibrary.org/obo/NCBITaxon_2732514	Revtraviricetes	http://purl.obolibrary.org/obo/NCBITaxon_2559587	Riboviria		
http://purl.obolibrary.org/obo/MRO_0001355	MHC class I protein complex	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001356	MHC class II protein complex	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001498	mouse MHC protein complex with H2-p haplotype	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001530	HLA protein complex with A2 serotype	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001533	HLA protein complex with A24 serotype	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001537	HLA protein complex with A28 serotype	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001538	HLA protein complex with A29 serotype	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001557	HLA protein complex with B27 serotype	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0001622	HLA protein complex with DQ3 serotype	http://purl.obolibrary.org/obo/GO_0042611	MHC protein complex		
http://purl.obolibrary.org/obo/MRO_0000973	H2-IAd protein complex	http://purl.obolibrary.org/obo/MRO_0000971	H2-IA protein complex		
http://purl.obolibrary.org/obo/MRO_0000975	H2-IAg7 protein complex	http://purl.obolibrary.org/obo/MRO_0000971	H2-IA protein complex		
http://purl.obolibrary.org/obo/MRO_0001434	cattle MHC class I protein complex	http://purl.obolibrary.org/obo/MRO_0001355	MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0001454	human MHC class I protein complex	http://purl.obolibrary.org/obo/MRO_0001355	MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex	http://purl.obolibrary.org/obo/MRO_0001355	MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0001465	pig MHC class I protein complex	http://purl.obolibrary.org/obo/MRO_0001355	MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0001790	rat MHC class I protein complex	http://purl.obolibrary.org/obo/MRO_0001355	MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0001435	cattle MHC class II protein complex	http://purl.obolibrary.org/obo/MRO_0001356	MHC class II protein complex		
http://purl.obolibrary.org/obo/MRO_0001455	human MHC class II protein complex	http://purl.obolibrary.org/obo/MRO_0001356	MHC class II protein complex		
http://purl.obolibrary.org/obo/MRO_0001461	mouse MHC class II protein complex	http://purl.obolibrary.org/obo/MRO_0001356	MHC class II protein complex		
http://purl.obolibrary.org/obo/MRO_0001793	rat MHC class II protein complex with RT1-A haplotype	http://purl.obolibrary.org/obo/MRO_0001356	MHC class II protein complex		
http://purl.obolibrary.org/obo/MRO_0001149	HLA-C protein complex	http://purl.obolibrary.org/obo/MRO_0001454	human MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0000013	HLA-DR protein complex	http://purl.obolibrary.org/obo/MRO_0001455	human MHC class II protein complex		
http://purl.obolibrary.org/obo/MRO_0001167	HLA-DP protein complex	http://purl.obolibrary.org/obo/MRO_0001455	human MHC class II protein complex		
http://purl.obolibrary.org/obo/MRO_0000967	H2-Dd protein complex	http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0000992	H2-Kd protein complex	http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0000994	H2-Ks protein complex	http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0000997	H2-Ld protein complex	http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0001759	mouse MHC class I protein complex with H2-b haplotype	http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0002026	H2-Dq protein complex	http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0002027	H2-Kq protein complex	http://purl.obolibrary.org/obo/MRO_0001460	mouse MHC class I protein complex		
http://purl.obolibrary.org/obo/MRO_0000971	H2-IA protein complex	http://purl.obolibrary.org/obo/MRO_0001461	mouse MHC class II protein complex		
http://purl.obolibrary.org/obo/MRO_0000966	H2-Db protein complex	http://purl.obolibrary.org/obo/MRO_0001759	mouse MHC class I protein complex with H2-b haplotype		
http://purl.obolibrary.org/obo/MRO_0000991	H2-Kb protein complex	http://purl.obolibrary.org/obo/MRO_0001759	mouse MHC class I protein complex with H2-b haplotype		
http://purl.obolibrary.org/obo/IAO_8000016	taxonomic bridge ontology module	http://purl.obolibrary.org/obo/IAO_8000004	bridge ontology module		
http://purl.obolibrary.org/obo/IAO_8000019	ontology module subsetted by OWL profile	http://purl.obolibrary.org/obo/IAO_8000017	ontology module subsetted by expressivity		
http://purl.obolibrary.org/obo/IAO_8000020	EL++ ontology module	http://purl.obolibrary.org/obo/IAO_8000019	ontology module subsetted by OWL profile		
http://purl.obolibrary.org/obo/RO_0002310	obsolete exposure event or process				OBSOLETE A process occurring within or in the vicinity of an organism that exerts some causal influence on the organism via the interaction between an exposure stimulus and an exposure receptor. The exposure stimulus may be a process, material entity or condition (for example, lack of nutrients). The exposure receptor can be an organism, organism population or a part of an organism.
http://purl.obolibrary.org/obo/RO_0002532	sequentially ordered entity				Any entity that is ordered in discrete units along a linear axis.
http://purl.obolibrary.org/obo/GO_0005634	nucleus				A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
http://purl.obolibrary.org/obo/BFO_0000001	entity				
http://www.geneontology.org/formats/oboInOwl#ObsoleteClass	Obsolete Class				
http://purl.obolibrary.org/obo/RO_0002234	has output	http://purl.obolibrary.org/obo/RO_0000057	has participant	produces	p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p.
http://purl.obolibrary.org/obo/RO_0000052	characteristic of	http://purl.obolibrary.org/obo/RO_0002314	characteristic of part of	inheres_in	a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence.
http://purl.obolibrary.org/obo/RO_0000079	function of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	is function of	a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000080	quality of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	quality_of	a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000085	has function	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_function	a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000086	has quality	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_quality	a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0002000	2D boundary of	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to	surface of	a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity
http://purl.obolibrary.org/obo/RO_0002002	has 2D boundary	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to	has_2D_boundary	a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity
http://purl.obolibrary.org/obo/RO_0002350	member of	http://purl.obolibrary.org/obo/BFO_0000050	part of	member part of	is member of is a mereological relation between a item and a collection.
http://purl.obolibrary.org/obo/BFO_0000051	has part	http://purl.obolibrary.org/obo/RO_0002131	overlaps	has_part	a core relation that holds between a whole and its part
http://purl.obolibrary.org/obo/RO_0000087	has role	http://purl.obolibrary.org/obo/RO_0000053	has characteristic	has_role	a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0002327	enables	http://purl.obolibrary.org/obo/RO_0002215	capable of	is executing	c enables p iff c is capable of p and c acts to execute p.
http://purl.obolibrary.org/obo/RO_0002409	indirectly negatively regulates	http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	indirectly inhibits	p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q.
http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	http://purl.obolibrary.org/obo/RO_0002434	interacts with	molecularly binds with	An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
http://purl.obolibrary.org/obo/RO_0002449	directly negatively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	directly inhibits	The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0002378	anabranch of	http://purl.obolibrary.org/obo/RO_0002377	distributary of	anastomoses with	x anabranch_of y if x is a distributary of y (i.e. it channels a from a larger flow from y) and x ultimately channels the flow back into y.
http://purl.obolibrary.org/obo/RO_0002524	has subsequence	http://purl.obolibrary.org/obo/RO_0002526	overlaps sequence of	contains	x has subsequence y iff all of the sequence parts of y are sequence parts of x
http://purl.obolibrary.org/obo/RO_0002525	is subsequence of	http://purl.obolibrary.org/obo/RO_0002526	overlaps sequence of	contained by	inverse of has subsequence
http://purl.obolibrary.org/obo/RO_0003305	contributes to severity of condition	http://purl.obolibrary.org/obo/RO_0003304	contributes to condition	contributes to expressivity of condition	A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the severity with which a condition manifests in an individual.
http://purl.obolibrary.org/obo/RO_0003306	contributes to frequency of condition	http://purl.obolibrary.org/obo/RO_0003304	contributes to condition	contributes to penetrance of condition	A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity influences the frequency of the condition in a population.
http://purl.obolibrary.org/obo/RO_0003307	ameliorates condition	http://purl.obolibrary.org/obo/RO_0003305	contributes to severity of condition	is preventative for condition	A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the presence of the entity reduces or eliminates some or all aspects of the condition.
http://purl.obolibrary.org/obo/RO_0002150	continuous with	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to	connected to	X continuous_with Y if and only if X and Y share a fiat boundary.
http://purl.obolibrary.org/obo/RO_0011013	indirectly positively regulates activity of	http://purl.obolibrary.org/obo/RO_0011004	indirectly regulates activity of	indirectly activates	The entity A is not immediately upstream of the entity B and has an activity that up-regulates an activity performed by B.
http://purl.obolibrary.org/obo/RO_0011016	indirectly negatively regulates activity of	http://purl.obolibrary.org/obo/RO_0011004	indirectly regulates activity of	indirectly inhibits	The entity A is not immediately upstream of the entity B and has an activity that down-regulates an activity performed by B.
http://purl.obolibrary.org/obo/BFO_0000062	preceded by	http://purl.obolibrary.org/obo/RO_0002086	ends after	preceded_by	x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/RO_0002156	derived by descent from	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to	evolutionarily_descended_from	d derived_by_descent_from a if d is specified by some genetic program that is sequence-inherited-from a genetic program that specifies a.
http://purl.obolibrary.org/obo/RO_0000081	role of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of	role_of	a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0017003	positively correlated with	http://purl.obolibrary.org/obo/RO_0002610	correlated with	directly correlated with	A relation between entities in which one increases or decreases as the other does the same.
http://purl.obolibrary.org/obo/RO_0017004	negatively correlated with	http://purl.obolibrary.org/obo/RO_0002610	correlated with	inversely correlated with	A relation between entities in which one increases as the other decreases.
http://purl.obolibrary.org/obo/BFO_0000050	part of	http://purl.obolibrary.org/obo/RO_0002131	overlaps	part_of	a core relation that holds between a part and its whole
http://purl.obolibrary.org/obo/RO_0002233	has input	http://purl.obolibrary.org/obo/RO_0000057	has participant	consumes	p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
http://purl.obolibrary.org/obo/RO_0002314	characteristic of part of	http://purl.obolibrary.org/obo/RO_0002502	depends on	inheres in part of	q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w.
http://purl.obolibrary.org/obo/RO_0002215	capable of	http://purl.obolibrary.org/obo/RO_0002216	capable of part of	has function realized in	A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process.
http://purl.obolibrary.org/obo/RO_0002331	involved in	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	enables part of	c involved_in p if and only if c enables some process p', and p' is part of p
http://purl.obolibrary.org/obo/RO_0002376	tributary of	http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with	tributary channel of	x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein.
http://purl.obolibrary.org/obo/RO_0002377	distributary of	http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with	distributary channel of	x distributary_of y if and only if x is capable of channeling the flow of a substance to y, where y channels less of the substance than x
http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	involved in or reguates	c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
http://purl.obolibrary.org/obo/RO_0002437	biotically interacts with	http://purl.obolibrary.org/obo/RO_0002321	ecologically related to	interacts with on organism level	An interaction relationship in which at least one of the partners is an organism and the other is either an organism or an abiotic entity with which the organism interacts.
http://purl.obolibrary.org/obo/RO_0002551	has skeleton	http://purl.obolibrary.org/obo/BFO_0000051	has part	has supporting framework	A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision.
http://purl.obolibrary.org/obo/RO_0002101	fasciculates with	http://purl.obolibrary.org/obo/RO_0002131	overlaps	fasciculates with	relationship between a neuron and a neuron projection bundle (e.g.- tract or nerve bundle) that one or more of its projections travels through.

http://purl.obolibrary.org/obo/RO_0002110	has postsynaptic terminal in	http://purl.obolibrary.org/obo/RO_0002130	has synaptic terminal in	synapsed in	Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. 
http://purl.obolibrary.org/obo/RO_0002113	has presynaptic terminal in	http://purl.obolibrary.org/obo/RO_0002130	has synaptic terminal in	synapses in	Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input.
http://purl.obolibrary.org/obo/RO_0002130	has synaptic terminal in	http://purl.obolibrary.org/obo/RO_0002131	overlaps	has synapse in	A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input.
http://purl.obolibrary.org/obo/RO_0002151	partially overlaps	http://purl.obolibrary.org/obo/RO_0002131	overlaps	proper overlaps	x partially overlaps y iff there exists some z such that z is part of x and z is part of y, and it is also the case that neither x is part of y or y is part of x
http://purl.obolibrary.org/obo/RO_0002216	capable of part of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	has function in	c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
http://purl.obolibrary.org/obo/RO_0002329	part of structure that is capable of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to	0	this relation holds between c and p when c is part of some c', and c' is capable of p.
http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	influences (processual)	p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q.
http://purl.obolibrary.org/obo/RO_0002132	has fasciculating neuron projection	http://purl.obolibrary.org/obo/RO_0002131	overlaps	has fasciculating component	The relation between a neuron projection bundle and a neuron projection that is fasciculated with it.
http://purl.obolibrary.org/obo/RO_0002210	directly develops into	http://purl.obolibrary.org/obo/RO_0002203	develops into	developmental precursor of	inverse of directly develops from
http://purl.obolibrary.org/obo/RO_0002224	starts with	http://purl.obolibrary.org/obo/RO_0002222	temporally related to	started by	x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/RO_0002230	ends with	http://purl.obolibrary.org/obo/RO_0002222	temporally related to	finished by	x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/RO_0002231	has start location	http://purl.obolibrary.org/obo/RO_0002479	has part that occurs in	starts with process that occurs in	x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y
http://purl.obolibrary.org/obo/RO_0002232	has end location	http://purl.obolibrary.org/obo/RO_0002479	has part that occurs in	ends with process that occurs in	x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y
http://purl.obolibrary.org/obo/RO_0002256	developmentally induced by	http://purl.obolibrary.org/obo/RO_0002258	developmentally preceded by	induced by	t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T
http://purl.obolibrary.org/obo/RO_0002285	developmentally replaces	http://purl.obolibrary.org/obo/RO_0002258	developmentally preceded by	replaces	x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else
http://purl.obolibrary.org/obo/RO_0002303	has habitat	http://purl.obolibrary.org/obo/RO_0002321	ecologically related to	adapted for living in	x 'has habitat' y if and only if: x is an organism, y is a habitat, and y can sustain and allow the growth of a population of xs.
http://purl.obolibrary.org/obo/RO_0002313	transports or maintains localization of	http://purl.obolibrary.org/obo/RO_0002337	related via localization to	regulates localization of	Holds between p and c when p is a localization process (localization covers maintenance of localization as well as its establishment)  and the outcome of this process is to regulate the localization of c.
http://purl.obolibrary.org/obo/RO_0002400	has direct input	http://purl.obolibrary.org/obo/RO_0002233	has input	directly consumes	p has direct input c iff c is a participant in p, c is present at the start of p, and the state of c is modified during p.
http://purl.obolibrary.org/obo/RO_0002407	indirectly positively regulates	http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	indirectly activates	p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q.
http://purl.obolibrary.org/obo/RO_0002413	provides input for	http://purl.obolibrary.org/obo/RO_0002414	transitively provides input for	directly provides input for	p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c.
http://purl.obolibrary.org/obo/RO_0002432	is active in	http://purl.obolibrary.org/obo/RO_0002328	functionally related to	executes activity in	c executes activity in d if and only if c enables p and p occurs_in d.  Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
http://purl.obolibrary.org/obo/RO_0002439	preys on	http://purl.obolibrary.org/obo/RO_0002438	trophically interacts with	preys upon	An interaction relationship involving a predation process, where the subject kills the target in order to eat it or to feed to siblings, offspring or group members
http://purl.obolibrary.org/obo/RO_0002444	parasite of	http://purl.obolibrary.org/obo/RO_0002454	has host	parasitizes	A parasite-host relationship where an organism benefits at the expense of another.
http://purl.obolibrary.org/obo/RO_0002445	parasitized by	http://purl.obolibrary.org/obo/RO_0002453	host of	parasitised by	Inverse of parasite of
http://purl.obolibrary.org/obo/RO_0002450	directly positively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	directly activates	The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. 
For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0002458	preyed upon by	http://purl.obolibrary.org/obo/RO_0002438	trophically interacts with	is target of predation interaction with	inverse of preys on
http://purl.obolibrary.org/obo/RO_0002470	eats	http://purl.obolibrary.org/obo/RO_0002437	biotically interacts with	is subject of eating interaction with	A biotic interaction where one organism consumes a material entity through a type of mouth or other oral opening.
http://purl.obolibrary.org/obo/RO_0002471	is eaten by	http://purl.obolibrary.org/obo/RO_0002437	biotically interacts with	is target of eating interaction with	Inverse of eats
http://purl.obolibrary.org/obo/RO_0002505	has intermediate	http://purl.obolibrary.org/obo/RO_0000057	has participant	has intermediate product	p has intermediate c if and only if p has parts p1, p2 and p1 has output c, and p2 has input c
http://purl.obolibrary.org/obo/RO_0002516	has start sequence	http://purl.obolibrary.org/obo/RO_0002524	has subsequence	started by	x has start sequence y if the start of x is identical to the start of y, and x has y as a subsequence
http://purl.obolibrary.org/obo/RO_0002517	is start sequence of	http://purl.obolibrary.org/obo/RO_0002525	is subsequence of	starts	inverse of has start sequence
http://purl.obolibrary.org/obo/RO_0002518	has end sequence	http://purl.obolibrary.org/obo/RO_0002524	has subsequence	ended by	x has end sequence y if the end of x is identical to the end of y, and x has y as a subsequence
http://purl.obolibrary.org/obo/RO_0002519	is end sequence of	http://purl.obolibrary.org/obo/RO_0002525	is subsequence of	ends	inverse of has end sequence
http://purl.obolibrary.org/obo/RO_0002527	does not overlap sequence of	http://purl.obolibrary.org/obo/RO_0002514	sequentially related to	disconnected from	x does not overlap the sequence of y if and only if there is no z such that x has a subsequence z and z is a subsequence of y.
http://purl.obolibrary.org/obo/RO_0002599	capable of inhibiting or preventing pathological process	http://purl.obolibrary.org/obo/RO_0002597	capable of negatively regulating	treats	Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a inhibits p.
http://purl.obolibrary.org/obo/RO_0002600	capable of upregulating or causing pathological process	http://purl.obolibrary.org/obo/RO_0002598	capable of positively regulating	causes disease	Holds between a material entity c and a pathological process p if and only if c is capable of some activity a, where a negatively regulates p.
http://purl.obolibrary.org/obo/RO_0002606	is substance that treats	http://purl.obolibrary.org/obo/RO_0002599	capable of inhibiting or preventing pathological process	treats	c is a substance that treats d if c is a material entity (such as a small molecule or compound) and d is a pathological process, phenotype or disease, and c is capable of some activity that negative regulates or decreases the magnitude of d.
http://purl.obolibrary.org/obo/RO_0004027	disease has inflammation site	http://purl.obolibrary.org/obo/RO_0004026	disease has location		A relationship between a disease and an anatomical entity where the disease is triggered by an inflammatory response to stimuli occurring in the anatomical entity
http://purl.obolibrary.org/obo/RO_0004028	realized in response to stimulus	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship between a realizable entity R (e.g. function or disposition) and a material entity M where R is realized in response to a process that has an input stimulus of M.
http://purl.obolibrary.org/obo/RO_0004029	disease has feature	http://purl.obolibrary.org/obo/RO_0040035	disease relationship		A relationship between a disease and some feature of that disease, where the feature is either a phenotype or an isolated disease.
http://purl.obolibrary.org/obo/RO_0004030	disease arises from alteration in structure	http://purl.obolibrary.org/obo/RO_0004019	disease has basis in		A relationship between a disease and an anatomical structure where the material basis of the disease is some pathological change in the structure. Anatomical structure includes cellular and sub-cellular entities, such as chromosome and organelles.
http://purl.obolibrary.org/obo/RO_0004009	has primary input	http://purl.obolibrary.org/obo/RO_0002233	has input		p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c.
http://purl.obolibrary.org/obo/RO_HOM0000001	in homology relationship with	http://purl.obolibrary.org/obo/RO_0002158	shares ancestor with		Similarity that results from common evolutionary origin.
http://purl.obolibrary.org/obo/RO_HOM0000016	in non functional homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000006	in structural homology relationship with		Structural homology that involves a pseudogenic feature and its functional ancestor.
http://purl.obolibrary.org/obo/RO_0002025	has effector activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity.
http://purl.obolibrary.org/obo/RO_0040036	results in changes to anatomical or cellular structure	http://purl.obolibrary.org/obo/RO_0000057	has participant		p has anatomical participant c iff p has participant c, and c is an anatomical entity
http://purl.obolibrary.org/obo/ENVO_02000200	has increased levels of	http://purl.obolibrary.org/obo/RO_0002180	has component		A has part relationship between a whole and a part, where the number of parts present in the whole is higher than in comparable entities.
http://purl.obolibrary.org/obo/RO_0002100	has soma location	http://purl.obolibrary.org/obo/RO_0002131	overlaps		Relation between a neuron and a material anatomical entity that its soma is part of.
http://purl.obolibrary.org/obo/RO_0002160	only in taxon	http://purl.obolibrary.org/obo/RO_0002162	in taxon		x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z.
http://purl.obolibrary.org/obo/RO_0002258	developmentally preceded by	http://purl.obolibrary.org/obo/RO_0002324	developmentally related to		Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p
http://purl.obolibrary.org/obo/RO_0002162	in taxon	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to		x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed.
http://purl.obolibrary.org/obo/RO_0002286	developmentally succeeded by	http://purl.obolibrary.org/obo/RO_0002384	has developmental potential involving		Inverse of developmentally preceded by
http://purl.obolibrary.org/obo/RO_0002371	attached to	http://purl.obolibrary.org/obo/RO_0002177	attached to part of		a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a
http://purl.obolibrary.org/obo/RO_0002384	has developmental potential involving	http://purl.obolibrary.org/obo/RO_0002324	developmentally related to		x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction).
http://purl.obolibrary.org/obo/RO_0002388	has potential to directly develop into	http://purl.obolibrary.org/obo/RO_0002387	has potential to develop into		x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y
http://purl.obolibrary.org/obo/RO_0002178	supplies	http://purl.obolibrary.org/obo/RO_0002170	connected to		Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy.
http://purl.obolibrary.org/obo/RO_0002372	has muscle origin	http://purl.obolibrary.org/obo/RO_0002567	biomechanically related to		m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to.
http://purl.obolibrary.org/obo/RO_0002374	derived from ancestral fusion of	http://purl.obolibrary.org/obo/RO_0002156	derived by descent from		x has_fused_element y iff: there exists some z : x has_part z, z homologous_to y, and y is a distinct element, the boundary between x and z is largely fiat
http://purl.obolibrary.org/obo/RO_0002380	branching part of	http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with		x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y
http://purl.obolibrary.org/obo/RO_0002476	child nucleus of	http://purl.obolibrary.org/obo/RO_0002258	developmentally preceded by		c is a child nucleus of d if and only if c and d are both nuclei and parts of cells c' and d', where c' is derived from d' by mitosis and the genetic material in c is a copy of the generic material in d
http://purl.obolibrary.org/obo/RO_0002477	child nucleus of in hermaphrodite	http://purl.obolibrary.org/obo/RO_0002476	child nucleus of		A child nucleus relationship in which the cells are part of a hermaphroditic organism
http://purl.obolibrary.org/obo/RO_0002478	child nucleus of in male	http://purl.obolibrary.org/obo/RO_0002476	child nucleus of		A child nucleus relationship in which the cells are part of a male organism
http://purl.obolibrary.org/obo/RO_0002568	has muscle antagonist	http://purl.obolibrary.org/obo/RO_0002567	biomechanically related to		m1 has_muscle_antagonist m2 iff m1 has_muscle_insertion s, m2 has_muscle_insection s, m1 acts in opposition to m2, and m2 is responsible for returning the structure to its initial position.
http://purl.obolibrary.org/obo/RO_0002569	has branching part	http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with		inverse of branching part of
http://purl.obolibrary.org/obo/RO_0002571	lumen of	http://purl.obolibrary.org/obo/BFO_0000050	part of		x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull.
http://purl.obolibrary.org/obo/RO_0004020	disease has basis in dysfunction of	http://purl.obolibrary.org/obo/RO_0004019	disease has basis in		A relation that holds between the disease and a material entity where the physical basis of the disease is a disorder of that material entity that affects its function.
http://purl.obolibrary.org/obo/RO_0004021	disease has basis in disruption of	http://purl.obolibrary.org/obo/RO_0004019	disease has basis in		A relation that holds between the disease and a process where the physical basis of the disease disrupts execution of a key biological process.
http://purl.obolibrary.org/obo/RO_0004022	disease has basis in feature	http://purl.obolibrary.org/obo/RO_0004019	disease has basis in		A relation that holds between the disease and a feature (a phenotype or other disease) where the physical basis of the disease is the feature.
http://purl.obolibrary.org/obo/RO_0004024	disease causes disruption of	http://purl.obolibrary.org/obo/RO_0004023	causal relationship with disease as subject		A relationship between a disease and a process where the disease process disrupts the execution of the process.
http://purl.obolibrary.org/obo/RO_0004007	has primary input or output	http://purl.obolibrary.org/obo/RO_0000057	has participant		p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c.
http://purl.obolibrary.org/obo/RO_0004008	has primary output	http://purl.obolibrary.org/obo/RO_0004007	has primary input or output		p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c.
http://purl.obolibrary.org/obo/BFO_0000063	precedes	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/IAO_0000219	denotes	http://purl.obolibrary.org/obo/IAO_0000136	is about		A primitive, instance-level, relation obtaining between an information content entity and some portion of reality. Denotation is what happens when someone creates an information content entity E in order to specifically refer to something. The only relation between E and the thing is that E can be used to 'pick out' the thing. This relation connects those two together. Freedictionary.com sense 3: To signify directly; refer to specifically
http://purl.obolibrary.org/obo/IAO_0000221	is quality measurement of	http://purl.obolibrary.org/obo/IAO_0000136	is about		m is a quality measurement of q at t. When q is a quality, there is a measurement process p that has specified output m, a measurement datum, that is about q
http://purl.obolibrary.org/obo/IAO_0000413	is duration of	http://purl.obolibrary.org/obo/IAO_0000136	is about		relates a process to a time-measurement-datum that represents the duration of the process
http://purl.obolibrary.org/obo/OBI_0000107	provides_service_consumer_with	http://purl.obolibrary.org/obo/BFO_0000051	has part		A relation between a service and the primary processual part of the service that is performed by the provider for the consumer.
http://purl.obolibrary.org/obo/OBI_0000293	has specified input	http://purl.obolibrary.org/obo/RO_0000057	has participant		The inverse property of is specified input of
http://purl.obolibrary.org/obo/OBI_0000295	is specified input of	http://purl.obolibrary.org/obo/RO_0000056	participates in		A relation between a planned process and a continuant participating in that process that is not created during  the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0000299	has specified output	http://purl.obolibrary.org/obo/RO_0000057	has participant		The inverse property of is specified output of
http://purl.obolibrary.org/obo/OBI_0000312	is specified output of	http://purl.obolibrary.org/obo/RO_0000056	participates in		A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of.
http://purl.obolibrary.org/obo/OBI_0000643	has grain	http://purl.obolibrary.org/obo/BFO_0000051	has part		the relation of the cells in the finger of the skin to the finger, in which an indeterminate number of grains are parts of the whole by virtue of being grains in a collective that is part of the whole, and in which removing one granular part does not nec- essarily damage or diminish the whole. Ontological Whether there is a fixed, or nearly fixed number of parts - e.g. fingers of the hand, chambers of the heart, or wheels of a car - such that there can be a notion of a single one being missing, or whether, by contrast, the number of parts is indeterminate - e.g., cells in the skin of the hand, red cells in blood, or rubber molecules in the tread of the tire of the wheel of the car.
http://purl.obolibrary.org/obo/OBI_0000645	is grain of	http://purl.obolibrary.org/obo/BFO_0000050	part of		A relation between granular parts and the whole of which they are a part. Granular parts have indeterminate number such that removing one granular part does not necessarily damage or diminish the whole.
http://purl.obolibrary.org/obo/OBI_0000999	has category label	http://purl.obolibrary.org/obo/BFO_0000051	has part		A relation between a categorical measurement data item and the categorical label that indicates the value of that data item on the categorical scale.
http://purl.obolibrary.org/obo/OBI_0001927	specifies value of	http://purl.obolibrary.org/obo/IAO_0000136	is about		A relation between a value specification and an entity which the specification is about.
http://purl.obolibrary.org/obo/OBI_0001937	has specified numeric value	http://purl.obolibrary.org/obo/OBI_0002135	has specified value		A relation between a value specification and a number that quantifies it.
http://purl.obolibrary.org/obo/OBI_0001938	has value specification	http://purl.obolibrary.org/obo/BFO_0000051	has part		A relation between an information content entity and a value specification that specifies its value.
http://purl.obolibrary.org/obo/OBI_0001950	has performer	http://purl.obolibrary.org/obo/RO_0000057	has participant		A relation between a planned process and a continuant where the continuant can be a person, organization or device (such as a robot controlled by software workflow management system) that performs the planned process.
http://purl.obolibrary.org/obo/OBI_1110060	process is result of	http://purl.obolibrary.org/obo/RO_0002087	immediately preceded by		is a relationship between a process and a preceding occurrent that directly caused the later one to occur
http://purl.obolibrary.org/obo/RO_0002219	surrounded by	http://purl.obolibrary.org/obo/RO_0002220	adjacent to		x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x
http://purl.obolibrary.org/obo/RO_0002220	adjacent to	http://purl.obolibrary.org/obo/RO_0002163	spatially disjoint from		x adjacent to y if and only if x and y share a boundary.
http://purl.obolibrary.org/obo/RO_0002223	starts	http://purl.obolibrary.org/obo/BFO_0000050	part of		inverse of starts with
http://purl.obolibrary.org/obo/RO_0002351	has member	http://purl.obolibrary.org/obo/BFO_0000051	has part		has member is a mereological relation between a collection and an item.
http://purl.obolibrary.org/obo/RO_0002018	has component process	http://purl.obolibrary.org/obo/RO_0002180	has component		w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0009005	has primary substance added	http://purl.obolibrary.org/obo/RO_0009001	has substance added		'has primary substance added' indicates that an entity has had the given substance added to it in a proportion greater than any other added substance.
http://purl.obolibrary.org/obo/RO_0007001	has disease driver	http://purl.obolibrary.org/obo/RO_0007000	has driver		A relation between an entity and a disease of a host, in which the entity is not part of the host itself, and the condition results in pathological processes.
http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0019001	positively regulates characteristic	http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic		A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0019002	negatively regulates characteristic	http://purl.obolibrary.org/obo/RO_0019000	regulates characteristic		A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C.
http://purl.obolibrary.org/obo/RO_0019501	confers susceptibility to condition	http://purl.obolibrary.org/obo/RO_0003304	contributes to condition		Relates a gene to condition, such that a variation in this gene predisposes to the development of a condition.
http://purl.obolibrary.org/obo/RO_0001020	is allergic trigger for	http://purl.obolibrary.org/obo/RO_0003302	causes or contributes to condition		A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
http://purl.obolibrary.org/obo/RO_0001021	is autoimmune trigger for	http://purl.obolibrary.org/obo/RO_0003302	causes or contributes to condition		A relation between a material entity and a condition (a phenotype or disease) of a host, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
http://purl.obolibrary.org/obo/RO_0002200	has phenotype	http://purl.obolibrary.org/obo/RO_0016001	has phenotype or disease		A relationship that holds between a biological entity and a phenotype. Here a phenotype is construed broadly as any kind of quality of an organism part, a collection of these qualities, or a change in quality or qualities (e.g. abnormally increased temperature). The subject of this relationship can be an organism (where the organism has the phenotype, i.e. the qualities inhere in parts of this organism), a genomic entity such as a gene or genotype (if modifications of the gene or the genotype causes the phenotype), or a condition such as a disease (such that if the condition inheres in an organism, then the organism has the phenotype).
http://purl.obolibrary.org/obo/RO_0002202	develops from	http://purl.obolibrary.org/obo/RO_0002254	has developmental contribution from		x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y
http://purl.obolibrary.org/obo/RO_0002451	transmitted by	http://purl.obolibrary.org/obo/RO_0002321	ecologically related to		A relationship that holds between a disease and organism
http://purl.obolibrary.org/obo/RO_0003304	contributes to condition	http://purl.obolibrary.org/obo/RO_0003302	causes or contributes to condition		A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some contributing role that influences the condition.
http://purl.obolibrary.org/obo/RO_0002309	has exposure stimulus	http://purl.obolibrary.org/obo/RO_0002244	related via exposure to		A relationship between an exposure event or process and any agent, stimulus, activity, or event that causally effects an organism and interacts with an exposure receptor during an exposure event.
http://purl.obolibrary.org/obo/RO_0016002	has disease	http://purl.obolibrary.org/obo/RO_0016001	has phenotype or disease		A relationship that holds between an organism and a disease. Here a disease is construed broadly as a disposition to undergo pathological processes that exists in an organism because of one or more disorders in that organism.
http://purl.obolibrary.org/obo/RO_0020332	assesses toxicity of	http://purl.obolibrary.org/obo/RO_0020334	indicates clinical effect of		A relationship between a biomarker 'b' and an exposure agent 'e', where 'b' is used to indicate the likelihood, presence, or extent of toxicity as an adverse effect of exposure to 'e'.
http://purl.obolibrary.org/obo/RO_0002176	connects	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system.
http://purl.obolibrary.org/obo/RO_0002491	existence starts and ends during	http://purl.obolibrary.org/obo/RO_0002492	existence ends during		x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y)
http://purl.obolibrary.org/obo/RO_0002333	enabled by	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of enables
http://purl.obolibrary.org/obo/RO_0002404	causally downstream of	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of upstream of
http://purl.obolibrary.org/obo/RO_0002412	immediately causally upstream of	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q.
http://purl.obolibrary.org/obo/RO_0002448	directly regulates activity of	http://purl.obolibrary.org/obo/RO_0011002	regulates activity of		The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.

A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B.
http://purl.obolibrary.org/obo/RO_0002566	causally influences	http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities		The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size).
http://purl.obolibrary.org/obo/RO_0003302	causes or contributes to condition	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal or contributing role that influences the condition.
http://purl.obolibrary.org/obo/RO_0003303	causes condition	http://purl.obolibrary.org/obo/RO_0003302	causes or contributes to condition		A relationship between an entity (e.g. a genotype, genetic variation, chemical, or environmental exposure) and a condition (a phenotype or disease), where the entity has some causal role for the condition.
http://purl.obolibrary.org/obo/RO_0003308	correlated with condition	http://purl.obolibrary.org/obo/RO_0002610	correlated with		A relationship between an entity and a condition (phenotype or disease) with which it exhibits a statistical dependence relationship.
http://purl.obolibrary.org/obo/RO_0002490	existence overlaps	http://purl.obolibrary.org/obo/RO_0002487	relation between physical entity and a process or stage		x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y))
http://purl.obolibrary.org/obo/RO_0002208	parasitoid of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A parasite that kills or sterilizes its host
http://purl.obolibrary.org/obo/RO_0002209	has parasitoid	http://purl.obolibrary.org/obo/RO_0002445	parasitized by		inverse of parasitoid of
http://purl.obolibrary.org/obo/RO_0002235	stem parasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A parasite-of relationship in which the host is a plant and the parasite that attaches to the host stem (PO:0009047)
http://purl.obolibrary.org/obo/RO_0002236	root parasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A parasite-of relationship in which the host is a plant and the parasite that attaches to the host root (PO:0009005)
http://purl.obolibrary.org/obo/RO_0002237	hemiparasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A sub-relation of parasite-of in which the parasite is a plant, and the parasite is parasitic under natural conditions and is also photosynthetic to some degree. Hemiparasites may just obtain water and mineral nutrients from the host plant. Many obtain at least part of their organic nutrients from the host as well.
http://purl.obolibrary.org/obo/RO_0001022	has allergic trigger	http://purl.obolibrary.org/obo/RO_0003302	causes or contributes to condition		A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is not part of the host, and is considered harmless to non-allergic hosts, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
http://purl.obolibrary.org/obo/RO_0001023	has autoimmune trigger	http://purl.obolibrary.org/obo/RO_0003302	causes or contributes to condition		A relation between a condition (a phenotype or disease) of a host and a material entity, in which the material entity is part of the host itself, and the condition results in pathological processes that include an abnormally strong immune response against the material entity.
http://purl.obolibrary.org/obo/RO_0002012	occurrent part of	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		A part of relation that applies only between occurrents.
http://purl.obolibrary.org/obo/RO_0002240	has exposure receptor	http://purl.obolibrary.org/obo/RO_0002244	related via exposure to		A broad relationship between an exposure event or process and any entity (e.g., an organism, organism population, or an organism part) that interacts with an exposure stimulus during the exposure event.
http://purl.obolibrary.org/obo/RO_0002241	has exposure stressor	http://purl.obolibrary.org/obo/RO_0002309	has exposure stimulus		A broad relationship between an exposure event or process and any agent, stimulus, activity, or event that causes stress or tension on an organism and interacts with an exposure receptor during an exposure event.
http://purl.obolibrary.org/obo/RO_0002242	has exposure route	http://purl.obolibrary.org/obo/RO_0002244	related via exposure to		A broad relationship between an exposure event or process and a process by which the exposure stressor comes into contact with the exposure receptor
http://purl.obolibrary.org/obo/RO_0002243	has exposure transport path	http://purl.obolibrary.org/obo/RO_0002244	related via exposure to		A broad relationship between an exposure event or process and the course takes from the source to the target.
http://purl.obolibrary.org/obo/RO_0002244	related via exposure to	http://purl.obolibrary.org/obo/RO_0002410	causally related to		Any relationship between an exposure event or process and any other entity.
http://purl.obolibrary.org/obo/RO_0002245	over-expressed in	http://purl.obolibrary.org/obo/RO_0002206	expressed in		g is over-expressed in t iff g is expressed in t, and the expression level of g is increased relative to some background.
http://purl.obolibrary.org/obo/RO_0002246	under-expressed in	http://purl.obolibrary.org/obo/RO_0002206	expressed in		g is under-expressed in t iff g is expressed in t, and the expression level of g is decreased relative to some background.
http://purl.obolibrary.org/obo/RO_0002248	has active ingredient	http://purl.obolibrary.org/obo/BFO_0000051	has part		A relationship that holds between a substance and a chemical entity, if the chemical entity is part of the substance, and the chemical entity forms the biologically active component of the substance.
http://purl.obolibrary.org/obo/RO_0002249	active ingredient in	http://purl.obolibrary.org/obo/BFO_0000050	part of		inverse of has active ingredient
http://purl.obolibrary.org/obo/RO_0002252	connecting branch of	http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with		b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t.
http://purl.obolibrary.org/obo/RO_0002253	has connecting branch	http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with		inverse of connecting branch of
http://purl.obolibrary.org/obo/RO_0002260	has biological role	http://purl.obolibrary.org/obo/RO_0000087	has role		c has-biological-role r iff c has-role r and r is a biological role (CHEBI:24432)
http://purl.obolibrary.org/obo/RO_0002261	has application role	http://purl.obolibrary.org/obo/RO_0000087	has role		c has-application-role r iff c has-role r and r is an application role (CHEBI:33232)
http://purl.obolibrary.org/obo/RO_0002262	has chemical role	http://purl.obolibrary.org/obo/RO_0000087	has role		c has-chemical-role r iff c has-role r and r is a chemical role (CHEBI:51086)
http://purl.obolibrary.org/obo/RO_0002263	acts upstream of	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
http://purl.obolibrary.org/obo/RO_0002302	is treated by substance	http://purl.obolibrary.org/obo/RO_0002410	causally related to		Inverse of 'is substance that treats'
http://purl.obolibrary.org/obo/RO_0002304	causally upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect		p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q.
http://purl.obolibrary.org/obo/RO_0002305	causally upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect		p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q.
http://purl.obolibrary.org/obo/RO_HOM0000002	in homoplasy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000000	in similarity relationship with		Similarity that results from independent evolution.
http://purl.obolibrary.org/obo/RO_HOM0000003	in homocracy relationship with	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to		Similarity that is characterized by the organization of anatomical structures through the expression of homologous or identical patterning genes.
http://purl.obolibrary.org/obo/RO_HOM0000004	in convergence relationship with	http://purl.obolibrary.org/obo/RO_HOM0000002	in homoplasy relationship with		Homoplasy that involves different underlying mechanisms or structures.
http://purl.obolibrary.org/obo/RO_HOM0000005	in parallelism relationship with	http://purl.obolibrary.org/obo/RO_HOM0000002	in homoplasy relationship with		Homoplasy that involves homologous underlying mechanisms or structures.
http://purl.obolibrary.org/obo/RO_HOM0000006	in structural homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000001	in homology relationship with		Homology that is defined by similarity with regard to selected structural parameters.
http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000001	in homology relationship with		Homology that is defined by common descent.
http://purl.obolibrary.org/obo/RO_HOM0000008	in biological homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000001	in homology relationship with		Homology that is defined by sharing of a set of developmental constraints, caused by locally acting self-regulatory mechanisms of differentiation, between individualized parts of the phenotype.
http://purl.obolibrary.org/obo/RO_HOM0000009	in reversal relationship with	http://purl.obolibrary.org/obo/RO_HOM0000002	in homoplasy relationship with		Homoplasy that involves phenotypes similar to those seen in ancestors within the lineage.
http://purl.obolibrary.org/obo/RO_HOM0000010	in syntenic homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000006	in structural homology relationship with		Structural homology that is detected by similarity in content and organization between chromosomes.
http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves genes that diverged after a duplication event.
http://purl.obolibrary.org/obo/RO_HOM0000012	in syntenic paralogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that involves sets of syntenic blocks.
http://purl.obolibrary.org/obo/RO_HOM0000013	in syntenic orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000010	in syntenic homology relationship with		Syntenic homology that involves chromosomes of different species.
http://purl.obolibrary.org/obo/RO_HOM0000014	in partial homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000006	in structural homology relationship with		Structural homology that involves complex structures from which only a fraction of the elements that can be isolated are separately homologous.
http://purl.obolibrary.org/obo/RO_HOM0000015	in protein structural homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000006	in structural homology relationship with		Structural homology that is detected at the level of the 3D protein structure, but maybe not at the level of the amino acid sequence.
http://purl.obolibrary.org/obo/RO_HOM0000017	in orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves genes that diverged after a speciation event.
http://purl.obolibrary.org/obo/RO_HOM0000018	in xenology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that is characterized by an interspecies (horizontal) transfer since the common ancestor.
http://purl.obolibrary.org/obo/RO_HOM0000019	in 1 to 1 homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves two members sharing no other homologs in the lineages considered.
http://purl.obolibrary.org/obo/RO_HOM0000020	in 1 to 1 orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000019	in 1 to 1 homology relationship with		Orthology that involves two genes that did not experience any duplication after the speciation event that created them.
http://purl.obolibrary.org/obo/RO_HOM0000022	in ohnology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that results from a whole genome duplication event.
http://purl.obolibrary.org/obo/RO_HOM0000023	in in-paralogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that results from a lineage-specific duplication subsequent to a given speciation event.
http://purl.obolibrary.org/obo/RO_HOM0000024	in out-paralogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that results from a duplication preceding a given speciation event.
http://purl.obolibrary.org/obo/RO_HOM0000025	in pro-orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000034	in 1 to many orthology relationship with		1:many orthology that involves a gene in species A and one of its ortholog in species B, when duplications more recent than the species split have occurred in species B but not in species A.
http://purl.obolibrary.org/obo/RO_HOM0000026	in semi-orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000034	in 1 to many orthology relationship with		1:many orthology that involves a gene in species A and its ortholog in species B, when duplications more recent than the species split have occurred in species A but not in species B.
http://purl.obolibrary.org/obo/RO_HOM0000027	in serial homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000066	in iterative homology relationship with		Iterative homology that involves structures arranged along the main body axis.
http://purl.obolibrary.org/obo/RO_HOM0000028	in heterochronous homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000008	in biological homology relationship with		Biological homology that is characterized by changes, over evolutionary time, in the rate or timing of developmental events of homologous structures.
http://purl.obolibrary.org/obo/RO_HOM0000029	in paedomorphorsis relationship with	http://purl.obolibrary.org/obo/RO_HOM0000028	in heterochronous homology relationship with		Heterochronous homology that is produced by a retention in adults of a species of traits previously seen only in juveniles.
http://purl.obolibrary.org/obo/RO_HOM0000030	in peramorphosis relationship with	http://purl.obolibrary.org/obo/RO_HOM0000028	in heterochronous homology relationship with		Heterochronous homology that is produced by a maturation of individuals of a species past adulthood, which take on hitherto unseen traits.
http://purl.obolibrary.org/obo/RO_HOM0000031	in progenesis relationship with	http://purl.obolibrary.org/obo/RO_HOM0000029	in paedomorphorsis relationship with		Paedomorphosis that is produced by precocious sexual maturation of an organism still in a morphologically juvenile stage.
http://purl.obolibrary.org/obo/RO_HOM0000032	in neoteny relationship with	http://purl.obolibrary.org/obo/RO_HOM0000029	in paedomorphorsis relationship with		Paedomorphosis that is produced by a retardation of somatic development.
http://purl.obolibrary.org/obo/RO_HOM0000033	in mimicry relationship with	http://purl.obolibrary.org/obo/RO_HOM0000004	in convergence relationship with		Convergence that results from co-evolution usually involving an evolutionary arms race.
http://purl.obolibrary.org/obo/RO_HOM0000034	in 1 to many orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000037	in 1 to many homology relationship with		Orthology that involves two genes when duplications more recent than the species split have occurred in one species but not the other.
http://purl.obolibrary.org/obo/RO_HOM0000036	in many to many homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves two members of a larger set of homologs.
http://purl.obolibrary.org/obo/RO_HOM0000037	in 1 to many homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves a structure that has no other homologs in the species in which it is defined, and several homologous structures in another species.
http://purl.obolibrary.org/obo/RO_HOM0000042	in apomorphy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that is based on recent shared ancestry, characterizing a monophyletic group.
http://purl.obolibrary.org/obo/RO_HOM0000043	in plesiomorphy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that is based on distant shared ancestry.
http://purl.obolibrary.org/obo/RO_HOM0000044	in deep homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000005	in parallelism relationship with		Homocracy that involves morphologically and phylogenetically disparate structures that are the result of parallel evolution.
http://purl.obolibrary.org/obo/RO_HOM0000045	in hemiplasy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that is characterized by topological discordance between a gene tree and a species tree attributable to the phylogenetic sorting of genetic polymorphisms across successive nodes in a species tree.
http://purl.obolibrary.org/obo/RO_HOM0000046	in gametology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000047	in chromosomal homology relationship with		Historical homology that involves not recombining and subsequently differentiated sex chromosomes.
http://purl.obolibrary.org/obo/RO_HOM0000047	in chromosomal homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves the chromosomes able to pair (synapse) during meiosis.
http://purl.obolibrary.org/obo/RO_HOM0000048	in many to many orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000036	in many to many homology relationship with		Orthology that involves two genes that experienced duplications more recent than the species split that created them.
http://purl.obolibrary.org/obo/RO_HOM0000049	in within-species paralogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that involves genes from the same species.
http://purl.obolibrary.org/obo/RO_HOM0000050	in between-species paralogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that involves genes from different species.
http://purl.obolibrary.org/obo/RO_HOM0000051	in postdisplacement relationship with	http://purl.obolibrary.org/obo/RO_HOM0000029	in paedomorphorsis relationship with		Paedomorphosis that is produced by delayed growth of immature structures into the adult form.
http://purl.obolibrary.org/obo/RO_HOM0000052	in hypermorphosis relationship with	http://purl.obolibrary.org/obo/RO_HOM0000030	in peramorphosis relationship with		Peramorphosis that is produced by a delay in the offset of development.
http://purl.obolibrary.org/obo/RO_HOM0000053	in synology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000018	in xenology relationship with		Xenology that results, not from the transfer of a gene between two species, but from a hybridization of two species.
http://purl.obolibrary.org/obo/RO_HOM0000054	in isoorthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000062	in equivalogy relationship with		Orthology that involves functional equivalent genes with retention of the ancestral function.
http://purl.obolibrary.org/obo/RO_HOM0000055	in tandem paralogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that is characterized by duplication of adjacent sequences on a chromosome segment.
http://purl.obolibrary.org/obo/RO_HOM0000057	in latent homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000058	in syngeny relationship with		Parallelism that involves morphologically very similar structures, occurring only within some members of a taxon and absent in the common ancestor (which possessed the developmental basis to develop this character).
http://purl.obolibrary.org/obo/RO_HOM0000058	in syngeny relationship with	http://purl.obolibrary.org/obo/RO_HOM0000003	in homocracy relationship with		Homocracy that involves recognizably corresponding characters that occurs in two or more taxa, or as a repeated unit within an individual.
http://purl.obolibrary.org/obo/RO_HOM0000060	in apparent orthology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000050	in between-species paralogy relationship with		Between-species paralogy that involves single copy paralogs resulting from reciprocal gene loss.
http://purl.obolibrary.org/obo/RO_HOM0000061	in pseudoparalogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000018	in xenology relationship with		Xenology that involves genes that ended up in a given genome as a result of a combination of vertical inheritance and horizontal gene transfer.
http://purl.obolibrary.org/obo/RO_HOM0000062	in equivalogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000065	in functional equivalence relationship with		Historical homology that involves functional equivalent genes with retention of the ancestral function.
http://purl.obolibrary.org/obo/RO_HOM0000063	in interology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves orthologous pairs of interacting molecules in different organisms.
http://purl.obolibrary.org/obo/RO_HOM0000065	in functional equivalence relationship with	http://purl.obolibrary.org/obo/RO_HOM0000000	in similarity relationship with		Similarity that is characterized by interchangeability in function.
http://purl.obolibrary.org/obo/RO_HOM0000066	in iterative homology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000008	in biological homology relationship with		Biological homology that involves parts of the same organism.
http://purl.obolibrary.org/obo/RO_HOM0000068	in paraxenology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000018	in xenology relationship with		Xenology that is characterized by multiple horizontal transfer events, resulting in the presence of two or more copies of the foreign gene in the host genome.
http://purl.obolibrary.org/obo/RO_HOM0000069	in plerology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000011	in paralogy relationship with		Paralogy that is characterized by extra similarity between paralogous sequences resulting from concerted evolution.
http://purl.obolibrary.org/obo/RO_HOM0000071	in homotopy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000006	in structural homology relationship with		Structural homology that involves structures with the same or similar relative positions.
http://purl.obolibrary.org/obo/RO_HOM0000072	in homeosis relationship with	http://purl.obolibrary.org/obo/RO_HOM0000008	in biological homology relationship with		Biological homology that involves an ectopic structure and the normally positioned structure.
http://purl.obolibrary.org/obo/RO_HOM0000073	in homoeology relationship with	http://purl.obolibrary.org/obo/RO_HOM0000053	in synology relationship with		Synology that results from allopolyploidy.
http://purl.obolibrary.org/obo/RO_HOM0000074	in paramorphism relationship with	http://purl.obolibrary.org/obo/RO_HOM0000066	in iterative homology relationship with		Iterative homology that involves two structures, one of which originated as a duplicate of the other and co-opted the expression of patterning genes of the ancestral structure.
http://purl.obolibrary.org/obo/RO_HOM0000075	in regulogy relationship with	http://purl.obolibrary.org/obo/RO_HOM0000007	in historical homology relationship with		Historical homology that involves orthologous pairs of transcription factors and downstream regulated genes in different organisms.
http://purl.obolibrary.org/obo/RO_0002131	overlaps	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		x overlaps y if and only if there exists some z such that x has part z and z part of y
http://purl.obolibrary.org/obo/RO_0002254	has developmental contribution from	http://purl.obolibrary.org/obo/RO_0002258	developmentally preceded by		x has developmental contribution from y iff x has some part z such that z develops from y
http://purl.obolibrary.org/obo/RO_0002496	existence starts during or after	http://purl.obolibrary.org/obo/RO_0002487	relation between physical entity and a process or stage		x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y).
http://purl.obolibrary.org/obo/RO_0002497	existence ends during or before	http://purl.obolibrary.org/obo/RO_0002487	relation between physical entity and a process or stage		x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends.
http://purl.obolibrary.org/obo/RO_0000091	has disposition	http://purl.obolibrary.org/obo/RO_0000053	has characteristic		a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence
http://purl.obolibrary.org/obo/RO_0000092	disposition of	http://purl.obolibrary.org/obo/RO_0000052	characteristic of		inverse of has disposition
http://purl.obolibrary.org/obo/RO_0011002	regulates activity of	http://purl.obolibrary.org/obo/RO_0002566	causally influences		The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0011003	regulates quantity of	http://purl.obolibrary.org/obo/RO_0002566	causally influences		The entity A has an activity that regulates the quantity or abundance or concentration of the entity B.
http://purl.obolibrary.org/obo/RO_0011004	indirectly regulates activity of	http://purl.obolibrary.org/obo/RO_0011002	regulates activity of		The entity A is not immediately upstream of the entity B but A has an activity that regulates an activity performed by B.
http://purl.obolibrary.org/obo/RO_0011007	decreases by repression quantity of	http://purl.obolibrary.org/obo/RO_0011023	indirectly negatively regulates quantity of		The entity A has an activity that down-regulates by repression the quantity of B. The down-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B.

For example, protein A (transcription factor) indirectly decreases by repression the quantity of protein B (gene product) if and only if A negatively regulates the process of transcription or translation of a nucleic acid element that produces B.
http://purl.obolibrary.org/obo/RO_0011008	increases by expression quantity of	http://purl.obolibrary.org/obo/RO_0011024	indirectly positively regulates quantity of		The entity A has an activity that up-regulates by expression the quantity of B. The up-regulation is due to A having an effect on an intermediate entity (typically a DNA or mRNA element) which can produce B.

For example, protein A (transcription factor) indirectly increases by expression the quantity of protein B (gene product) if and only if A positively regulates the process of transcription or translation of a nucleic acid element that produces B.
http://purl.obolibrary.org/obo/RO_0011009	directly positively regulates quantity of	http://purl.obolibrary.org/obo/RO_0011021	directly regulates quantity of		The entity A has an activity that directly positively regulates the quantity of B.
http://purl.obolibrary.org/obo/RO_0011010	directly negatively regulates quantity of	http://purl.obolibrary.org/obo/RO_0011021	directly regulates quantity of		The entity A has an activity that directly negatively regulates the quantity of B.
http://purl.obolibrary.org/obo/RO_0011014	destabilizes quantity of	http://purl.obolibrary.org/obo/RO_0011010	directly negatively regulates quantity of		An entity A directly interacts with B and A has an activity that decreases the amount of an entity B by degradating it.
http://purl.obolibrary.org/obo/RO_0011015	stabilizes quantity of	http://purl.obolibrary.org/obo/RO_0011009	directly positively regulates quantity of		An entity A physically interacts with B and A has an activity that increases the amount of an entity B by stabilizing it.
http://purl.obolibrary.org/obo/RO_0011021	directly regulates quantity of	http://purl.obolibrary.org/obo/RO_0011003	regulates quantity of		The entity A, immediately upstream of B, has an activity that directly regulates the quantity of B.
http://purl.obolibrary.org/obo/RO_0011022	indirectly regulates quantity of	http://purl.obolibrary.org/obo/RO_0011003	regulates quantity of		The entity A is not immediately upstream of the entity B, but A has an activity that regulates the quantity or abundance or concentration of B.
http://purl.obolibrary.org/obo/RO_0011023	indirectly negatively regulates quantity of	http://purl.obolibrary.org/obo/RO_0011022	indirectly regulates quantity of		The entity A does not physically interact with the entity B, and A has an activity that down-regulates the quantity or abundance or concentration of B.
http://purl.obolibrary.org/obo/RO_0011024	indirectly positively regulates quantity of	http://purl.obolibrary.org/obo/RO_0011022	indirectly regulates quantity of		The entity A does not physically interact with the entity B, and A has an activity that up-regulates the quantity or abundance or concentration of B.
http://purl.obolibrary.org/obo/RO_0012000	has small molecule regulator	http://purl.obolibrary.org/obo/RO_0000057	has participant		a relation between a process and a continuant, in which the process is regulated by the small molecule continuant
http://purl.obolibrary.org/obo/RO_0012001	has small molecule activator	http://purl.obolibrary.org/obo/RO_0012000	has small molecule regulator		a relation between a process and a continuant, in which the process is activated by the small molecule continuant
http://purl.obolibrary.org/obo/RO_0012002	has small molecule inhibitor	http://purl.obolibrary.org/obo/RO_0012000	has small molecule regulator		a relation between a process and a continuant, in which the process is inhibited by the small molecule continuant
http://purl.obolibrary.org/obo/RO_0012003	acts on population of	http://purl.obolibrary.org/obo/RO_0000057	has participant		p acts on population of c iff c' is a collection, has members of type c, and p has participant c
http://purl.obolibrary.org/obo/RO_0012004	is small molecule regulator of	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		a relation between a continuant and a process, in which the continuant is a small molecule that regulates the process
http://purl.obolibrary.org/obo/RO_0012005	is small molecule activator of	http://purl.obolibrary.org/obo/RO_0002598	capable of positively regulating		a relation between a continuant and a process, in which the continuant is a small molecule that activates the process
http://purl.obolibrary.org/obo/RO_0012006	is small molecule inhibitor of	http://purl.obolibrary.org/obo/RO_0002597	capable of negatively regulating		a relation between a continuant and a process, in which the continuant is a small molecule that inhibits the process
http://purl.obolibrary.org/obo/RO_0013001	has synaptic IO in region	http://purl.obolibrary.org/obo/RO_0002130	has synaptic terminal in		A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses in that region.
http://purl.obolibrary.org/obo/RO_0013002	receives synaptic input in region	http://purl.obolibrary.org/obo/RO_0002110	has postsynaptic terminal in		A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses in that region.
http://purl.obolibrary.org/obo/RO_0013003	sends synaptic output to region	http://purl.obolibrary.org/obo/RO_0002113	has presynaptic terminal in		A relationship between a neuron and a region, where the neuron has a functionally relevant number of output synapses in that region.
http://purl.obolibrary.org/obo/RO_0013004	has synaptic IO throughout	http://purl.obolibrary.org/obo/RO_0013001	has synaptic IO in region		A relationship between a neuron and a region, where the neuron has a functionally relevant number of input and/or output synapses distributed throughout that region (rather than confined to a subregion).
http://purl.obolibrary.org/obo/RO_0013005	receives synaptic input throughout	http://purl.obolibrary.org/obo/RO_0013004	has synaptic IO throughout		A relationship between a neuron and a region, where the neuron has a functionally relevant number of input synapses distributed throughout that region (rather than confined to a subregion).
http://purl.obolibrary.org/obo/RO_0013006	sends synaptic output throughout	http://purl.obolibrary.org/obo/RO_0013004	has synaptic IO throughout		A relationship between a neuron and a region, where the neuron has a functionally relevant number output synapses distributed throughout that region (rather than confined to a subregion).
http://purl.obolibrary.org/obo/RO_0002411	causally upstream of	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q.
http://purl.obolibrary.org/obo/RO_0008509	has roost	http://purl.obolibrary.org/obo/RO_0002303	has habitat		x 'has roost' y if and only if: x is an organism, y is a habitat, and y can support rest behaviors x.
http://purl.obolibrary.org/obo/RO_0018031	is direct conjugate base of	http://purl.obolibrary.org/obo/RO_0018033	is deprotonated form of		A is a direct conjugate base of B if and only if A is chemical entity that is a Brønsted–Lowry Base (i.e., can receive a proton) and by receiving a particular proton transforms it into B.
http://purl.obolibrary.org/obo/RO_0018032	is direct conjugate acid of	http://purl.obolibrary.org/obo/RO_0018034	is protonated form of		A is a direct conjugate acid of B if and only if A is chemical entity that is a Brønsted–Lowry Acid (i.e., can give up a proton) and by removing a particular proton transforms it into B.
http://purl.obolibrary.org/obo/RO_0018033	is deprotonated form of	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		A is a deprotonated form of B if and only if A is chemical entity that is a Brønsted–Lowry Base (i.e., can receive a proton) and by adding some nonzero number of protons transforms it into B.

This is a transitive relationship and follows this design pattern: https://oborel.github.io/obo-relations/direct-and-indirect-relations.
http://purl.obolibrary.org/obo/RO_0018034	is protonated form of	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		A is a protonated form of B if and only if A is chemical entity that is a Brønsted–Lowry Acid (i.e., can give up a proton) and by removing some nonzero number of protons transforms it into B.

This is a transitive relationship and follows this design pattern: https://oborel.github.io/obo-relations/direct-and-indirect-relations.
http://purl.obolibrary.org/obo/RO_0018035	is matched small molecular pair with	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		A and B are a matched small molecular pair (MMP) if their chemical structures define by a single, relatively small, well-defined structural modification.

While this is normally called "matched molecular pair" in the cheminformatics literaturel, it is labeled as "matched small molecular pair" so as to reduce confusion with peptides and other macromolecules, which are also referenced as "molecules" in some contexts.

This relationship is symmetric, meaning if A is a MMP with B iff B is a MMP with A.

This relationship is not transitive, meaning that A is a MMP with B and B is a MMP with C, then A is not necessarily an MMP with C.
http://purl.obolibrary.org/obo/RO_0018036	is tautomer of	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		Two chemicals are tautomers if they can be readily interconverted.

This commonly refers to prototropy in which a hydrogen's position is changed, such as between ketones and enols. This is also often observed in heterocyclic rings, e.g., ones containing nitrogens and/or have aryl functional groups containing heteroatoms.
http://purl.obolibrary.org/obo/RO_0018037	is substitutent group from	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		Group A is a substituent group from Chemical B if A represents the functional part of A and includes information about where it is connected. A is not itself a chemical with a fully formed chemical graph, but is rather a partial graph with one or more connection points that can be used to attach to another chemical graph, typically as a functionalization.
http://purl.obolibrary.org/obo/RO_0018038	has functional parent	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		Chemical A has functional parent Chemical B if there is chemical transformation through which chemical B can be produced from chemical A. 

For example, the relationship between a salt and a freebased compound is a "has functional parent" relationship.
http://purl.obolibrary.org/obo/RO_0018039	is enantiomer of	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		Chemicals A and B are enantiomers if they share the same molecular graph except the change of the configuration of substituents around exactly one chiral center.

A chemical with no chiral centers can not have an enantiomer. A chemical with multiple chiral centers can have multiple enantiomers, but its enantiomers are not themselves enantiomers (they are diastereomers).
http://purl.obolibrary.org/obo/RO_0018040	has parent hydride	http://purl.obolibrary.org/obo/RO_0018030	chemical relationship		Chemical A has parent hydride Chemical B if there exists a molecular graphical transformation where functional groups on A are replaced with hydrogens in order to yield B.
http://purl.obolibrary.org/obo/RO_0002211	regulates	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q.
http://purl.obolibrary.org/obo/RO_0002212	negatively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q.
http://purl.obolibrary.org/obo/RO_0002213	positively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q.
http://purl.obolibrary.org/obo/RO_0002180	has component	http://purl.obolibrary.org/obo/BFO_0000051	has part		w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0002163	spatially disjoint from	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		A is spatially_disjoint_from B if and only if they have no parts in common
http://purl.obolibrary.org/obo/RO_0002352	input of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of has input
http://purl.obolibrary.org/obo/RO_0002353	output of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of has output
http://purl.obolibrary.org/obo/RO_0002473	composed primarily of	http://purl.obolibrary.org/obo/BFO_0000051	has part		x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y.
http://purl.obolibrary.org/obo/RO_0002104	has plasma membrane part	http://purl.obolibrary.org/obo/BFO_0000051	has part		Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part.
http://purl.obolibrary.org/obo/RO_0002203	develops into	http://purl.obolibrary.org/obo/RO_0002387	has potential to develop into		inverse of develops from
http://purl.obolibrary.org/obo/RO_0002387	has potential to develop into	http://purl.obolibrary.org/obo/RO_0002384	has developmental potential involving		x has the potential to develop into y iff x develops into y or if x is capable of developing into y
http://purl.obolibrary.org/obo/RO_0002020	transports	http://purl.obolibrary.org/obo/RO_0002313	transports or maintains localization of		Holds between p and c when p is a transport process or transporter activity and the outcome of this p is to move c from one location to another.
http://purl.obolibrary.org/obo/RO_0002021	occurs across	http://purl.obolibrary.org/obo/RO_0002479	has part that occurs in		A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization.
http://purl.obolibrary.org/obo/RO_0002023	directly negatively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
http://purl.obolibrary.org/obo/RO_0002024	directly positively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
http://purl.obolibrary.org/obo/RO_0015007	increased in magnitude relative to	http://purl.obolibrary.org/obo/RO_0015006	different in magnitude relative to		q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
http://purl.obolibrary.org/obo/RO_0020202	has numerator	http://purl.obolibrary.org/obo/BFO_0000051	has part		A relationship between a ratio or proportion and its dividend.
http://purl.obolibrary.org/obo/RO_0020203	has denominator	http://purl.obolibrary.org/obo/BFO_0000051	has part		A relationship between a ratio or proportion and its divisor.
http://purl.obolibrary.org/obo/RO_0008510	symbiotrophically interacts with	http://purl.obolibrary.org/obo/RO_0002438	trophically interacts with		A trophic interaction in which one organism acquires nutrients through a symbiotic relationship with another organism
http://purl.obolibrary.org/obo/RO_0008511	trophic parasite of	http://purl.obolibrary.org/obo/RO_0008510	symbiotrophically interacts with		A symbiotrophic interaction in which one organism acquires nutrients through a parasitic relationship with another organism
http://purl.obolibrary.org/obo/RO_0013010	synapses restricted to region	http://purl.obolibrary.org/obo/RO_0013001	has synaptic IO in region		A relationship between a neuron and a region, where all of the functionally relevant input and output synapses are in that region.
http://purl.obolibrary.org/obo/RO_0020301	has allelopath	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		inverse of allelopath of
http://purl.obolibrary.org/obo/PBPKO_10001	has_biological_process	http://purl.obolibrary.org/obo/BFO_0000051	has part		An object property which relates the different biological processes of the PBPK model
http://purl.obolibrary.org/obo/PBPKO_10002	has_compartment	http://purl.obolibrary.org/obo/BFO_0000051	has part		An object property which relates the different compartments of the PBPK model
http://purl.obolibrary.org/obo/PBPKO_10004	has_transporter	http://purl.obolibrary.org/obo/BFO_0000051	has part		An object property which relates the different transporters of the PBPK model
http://purl.obolibrary.org/obo/PBPKO_10005	has_parameter	http://purl.obolibrary.org/obo/BFO_0000051	has part		An object property which relates the different parameters of the PBPK model
http://purl.obolibrary.org/obo/PBPKO_10006	has_biochemical_parameter	http://purl.obolibrary.org/obo/PBPKO_10005	has_parameter		An object property which links the different biochemical parameters of the PBPK model
http://purl.obolibrary.org/obo/PBPKO_10007	has_physicochemical_parameter	http://purl.obolibrary.org/obo/PBPKO_10005	has_parameter		An object property which links the different physicochemical parameters of the PBPK model
http://purl.obolibrary.org/obo/PBPKO_10008	has_physiological_parameter	http://purl.obolibrary.org/obo/PBPKO_10005	has_parameter		An object property which links the different physiological parameters of the PBPK model
http://purl.obolibrary.org/obo/PBPKO_10009	has_route_of_exposure	http://purl.obolibrary.org/obo/PBPKO_10005	has_parameter		An object property which relates the different exposure routes of the PBPK model
http://purl.obolibrary.org/obo/RO_0002801	co-roosts with	http://purl.obolibrary.org/obo/RO_0008506	ecologically co-occurs with		Two or more individuals sharing the same roost site (cave, mine, tree or tree hollow, animal burrow, leaf tent, rock crack, space in man-made structure, etc.). Individuals that are sharing a communal roost may be said to be co-roosting. The roost may be either a day roost where the individuals rest during daytime hours, or a night roost where individuals roost to feed, groom, or rest in between flights and/or foraging bouts.  Communal roosting as thus defined is an umbrella term within which different specialized types -- which are not mutually exclusive -- may be recognized based on taxonomy and the temporal and spatial relationships of the individuals that are co-roosting.
http://purl.obolibrary.org/obo/RO_0013009	sends synaptic output to cell	http://purl.obolibrary.org/obo/RO_0002120	synapsed to		A relationship between a neuron and a cell that it has a functionally relevant number of chemical synapses to.
http://purl.obolibrary.org/obo/RO_0015008	decreased in magnitude relative to	http://purl.obolibrary.org/obo/RO_0015006	different in magnitude relative to		q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
http://purl.obolibrary.org/obo/RO_0012011	indirectly causally upstream of	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q.
http://purl.obolibrary.org/obo/RO_0012012	indirectly regulates	http://purl.obolibrary.org/obo/RO_0012011	indirectly causally upstream of		p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q.
http://purl.obolibrary.org/obo/RO_0002007	bounding layer of	http://purl.obolibrary.org/obo/BFO_0000050	part of		X outer_layer_of Y iff:
. X :continuant that bearer_of some PATO:laminar
. X part_of Y
. exists Z :surface
. X has_boundary Z
. Z boundary_of Y

has_boundary: http://purl.obolibrary.org/obo/RO_0002002
boundary_of: http://purl.obolibrary.org/obo/RO_0002000
http://purl.obolibrary.org/obo/RO_0002008	coincident with	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		A relation that holds between two linear structures that are approximately parallel to each other for their entire length and where either the two structures are adjacent to each other or one is part of the other.
http://purl.obolibrary.org/obo/RO_0002170	connected to	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b
http://purl.obolibrary.org/obo/RO_0002177	attached to part of	http://purl.obolibrary.org/obo/RO_0002567	biomechanically related to		a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b.
http://purl.obolibrary.org/obo/RO_0002179	drains	http://purl.obolibrary.org/obo/RO_0002170	connected to		Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure.
http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network.
http://purl.obolibrary.org/obo/RO_0002438	trophically interacts with	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		An interaction relationship in which the partners are related via a feeding relationship.
http://purl.obolibrary.org/obo/RO_0002457	acquires nutrients from	http://purl.obolibrary.org/obo/RO_0002437	biotically interacts with		Inverse of provides nutrients for
http://purl.obolibrary.org/obo/RO_0002469	provides nutrients for	http://purl.obolibrary.org/obo/RO_0002437	biotically interacts with		A biotic interaction where a material entity provides nutrition for an organism.
http://purl.obolibrary.org/obo/RO_0002503	towards	http://purl.obolibrary.org/obo/RO_0002502	depends on		q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2
http://purl.obolibrary.org/obo/RO_0002567	biomechanically related to	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		A relation that holds between elements of a musculoskeletal system or its analogs.
http://purl.obolibrary.org/obo/RO_0002003	electrically_synapsed_to	http://purl.obolibrary.org/obo/RO_0002170	connected to		A relation that holds between two neurons that are electrically coupled via gap junctions.
http://purl.obolibrary.org/obo/RO_0002004	tracheates	http://purl.obolibrary.org/obo/RO_0001025	located in		The relationship that holds between a trachea or tracheole and an antomical structure that is contained in (and so provides an oxygen supply to).
http://purl.obolibrary.org/obo/RO_0002105	synapsed_via_type_Ib_bouton_to	http://purl.obolibrary.org/obo/RO_0002120	synapsed to		A relation between a motor neuron and a muscle that it synapses to via a type Ib bouton.
http://purl.obolibrary.org/obo/RO_0002106	synapsed_via_type_Is_bouton_to	http://purl.obolibrary.org/obo/RO_0002120	synapsed to		A relation between a motor neuron and a muscle that it synapses to via a type Is bouton.
http://purl.obolibrary.org/obo/RO_0002107	synapsed_via_type_II_bouton_to	http://purl.obolibrary.org/obo/RO_0002120	synapsed to		A relation between a motor neuron and a muscle that it synapses to via a type II bouton.
http://purl.obolibrary.org/obo/RO_0002108	synapsed_by_via_type_II_bouton	http://purl.obolibrary.org/obo/RO_0002103	synapsed by		Relation between a muscle and a motor neuron that synapses to it via a type II bouton.
http://purl.obolibrary.org/obo/RO_0002109	synapsed_by_via_type_Ib_bouton	http://purl.obolibrary.org/obo/RO_0002103	synapsed by		Relation between a muscle and a motor neuron that synapses to it via a type Ib bouton.
http://purl.obolibrary.org/obo/RO_0002112	synapsed_by_via_type_Is_bouton	http://purl.obolibrary.org/obo/RO_0002103	synapsed by		Relation between a muscle and a motor neuron that synapses to it via a type Is bouton.
http://purl.obolibrary.org/obo/RO_0002114	synapsed_via_type_III_bouton_to	http://purl.obolibrary.org/obo/RO_0002120	synapsed to		A relation between a motor neuron and a muscle that it synapses to via a type III bouton.
http://purl.obolibrary.org/obo/RO_0002115	synapsed_by_via_type_III_bouton	http://purl.obolibrary.org/obo/RO_0002103	synapsed by		Relation between a muscle and a motor neuron that synapses to it via a type III bouton.

http://purl.obolibrary.org/obo/RO_0002373	has muscle insertion	http://purl.obolibrary.org/obo/RO_0002567	biomechanically related to		m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone.
http://purl.obolibrary.org/obo/RO_0002433	contributes to morphology of	http://purl.obolibrary.org/obo/RO_0002131	overlaps		p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm.
http://purl.obolibrary.org/obo/RO_0002488	existence starts during	http://purl.obolibrary.org/obo/RO_0002496	existence starts during or after		x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y).
http://purl.obolibrary.org/obo/RO_0002489	existence starts with	http://purl.obolibrary.org/obo/RO_0002488	existence starts during		x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y).
http://purl.obolibrary.org/obo/RO_0002492	existence ends during	http://purl.obolibrary.org/obo/RO_0002497	existence ends during or before		x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y).
http://purl.obolibrary.org/obo/RO_0002493	existence ends with	http://purl.obolibrary.org/obo/RO_0002492	existence ends during		x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y).
http://purl.obolibrary.org/obo/RO_0002494	transformation of	http://purl.obolibrary.org/obo/RO_0002202	develops from		x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships
http://purl.obolibrary.org/obo/RO_0002495	immediate transformation of	http://purl.obolibrary.org/obo/RO_0002207	directly develops from		x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t
http://purl.obolibrary.org/obo/RO_0002507	determined by	http://purl.obolibrary.org/obo/RO_0002559	causally influenced by		s determined by f if and only if s is a type of system, and f is a material entity that is part of s, such that f exerts a strong causal influence on the functioning of s, and the removal of f would cause the collapse of s.
http://purl.obolibrary.org/obo/RO_0002572	luminal space of	http://purl.obolibrary.org/obo/RO_0002571	lumen of		s is luminal space of x iff s is lumen_of x and s is an immaterial entity
http://purl.obolibrary.org/obo/RO_0002576	skeleton of	http://purl.obolibrary.org/obo/BFO_0000050	part of		inverse of has skeleton
http://purl.obolibrary.org/obo/RO_0008501	epiphyte of	http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with		An interaction relationship wherein a plant or algae is living on the outside surface of another plant.
http://purl.obolibrary.org/obo/RO_0008502	has epiphyte	http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with		inverse of epiphyte of
http://purl.obolibrary.org/obo/RO_0008503	kleptoparasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A sub-relation of parasite of in which a parasite steals resources from another organism, usually food or nest material
http://purl.obolibrary.org/obo/RO_0008504	kleptoparasitized by	http://purl.obolibrary.org/obo/RO_0002445	parasitized by		inverse of kleptoparasite of
http://purl.obolibrary.org/obo/RO_0008505	creates habitat for	http://purl.obolibrary.org/obo/RO_0002321	ecologically related to		An interaction relationship wherein one organism creates a structure or environment that is lived in by another organism.
http://purl.obolibrary.org/obo/RO_0008506	ecologically co-occurs with	http://purl.obolibrary.org/obo/RO_0002321	ecologically related to		An interaction relationship describing organisms that often occur together at the same time and space or in the same environment.
http://purl.obolibrary.org/obo/RO_0008507	lays eggs on	http://purl.obolibrary.org/obo/RO_0002618	visits		An interaction relationship in which organism a lays eggs on the outside surface of organism b. Organism b is neither helped nor harmed in the process of egg laying or incubation.
http://purl.obolibrary.org/obo/RO_0008508	has eggs laid on by	http://purl.obolibrary.org/obo/RO_0002619	visited by		inverse of lays eggs on
http://purl.obolibrary.org/obo/RO_0002019	has ligand	http://purl.obolibrary.org/obo/RO_0002233	has input		A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function.
http://purl.obolibrary.org/obo/RO_0003309	exacerbates condition	http://purl.obolibrary.org/obo/RO_0003305	contributes to severity of condition		A relationship between an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) and a condition (a phenotype or disease), where the presence of the entity worsens some or all aspects of the condition.
http://purl.obolibrary.org/obo/RO_0003310	condition ameliorated by	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are reduced or eliminated by the presence of the entity.
http://purl.obolibrary.org/obo/RO_0003311	condition exacerbated by	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship between a condition (a phenotype or disease) and an entity (e.g. a chemical, environmental exposure, or some form of genetic variation) where some or all aspects of the condition are worsened by the presence of the entity.
http://purl.obolibrary.org/obo/RO_0002026	in register with	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		A relationship that holds between two images, A and B, where:
A depicts X;
B depicts Y;
X and Y are both of type T'
C is a 2 layer image consiting of layers A and B;
A and B are aligned in C according to a shared co-ordinate framework so that common features of X and Y are co-incident with each other.
Note: A and B may be 2D or 3D.
Examples include: the relationship between two channels collected simultaneously from a confocal microscope; the relationship between an image dpeicting X and a painted annotation layer that delineates regions of X; the relationship between the tracing of a neuron on an EM stack and the co-ordinate space of the stack; the relationship between two separately collected images that have been brought into register via some image registration software.
http://purl.obolibrary.org/obo/RO_0004011	is causal gain of function germline mutation of in	http://purl.obolibrary.org/obo/RO_0004010	is genetic basis for condition		Relates a gene to condition, such that a mutation in this gene in a germ cell provides a new function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
http://purl.obolibrary.org/obo/RO_0004012	is causal loss of function germline mutation of in	http://purl.obolibrary.org/obo/RO_0004010	is genetic basis for condition		Relates a gene to condition, such that a mutation in this gene in a germ cell impairs the function of the corresponding product and that is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
http://purl.obolibrary.org/obo/RO_0004013	is causal germline mutation in	http://purl.obolibrary.org/obo/RO_0004010	is genetic basis for condition		Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition and that can be passed on to offspring[modified from orphanet].
http://purl.obolibrary.org/obo/RO_0004014	is causal somatic mutation in	http://purl.obolibrary.org/obo/RO_0004010	is genetic basis for condition		Relates a gene to condition, such that a mutation in this gene is sufficient to produce the condition but that cannot be passed on to offspring[modified from orphanet].
http://purl.obolibrary.org/obo/RO_0004015	is causal susceptibility factor for	http://purl.obolibrary.org/obo/RO_0004010	is genetic basis for condition		Relates a gene to condition, such that a mutation in this gene predisposes to the development of a condition  and that is necessary but not sufficient to develop the condition[modified from orphanet].
http://purl.obolibrary.org/obo/RO_0004016	is causal germline mutation partially giving rise to	http://purl.obolibrary.org/obo/RO_0004010	is genetic basis for condition		Relates a gene to condition, such that a mutation in this gene partially contributes to the presentation of this condition[modified from orphanet].
http://purl.obolibrary.org/obo/RO_0004031	enables subfunction	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
http://purl.obolibrary.org/obo/RO_0004034	acts upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect		c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
http://purl.obolibrary.org/obo/RO_0004035	acts upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect		c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
http://purl.obolibrary.org/obo/RO_0018027	is agonist of	http://purl.obolibrary.org/obo/RO_0002450	directly positively regulates activity of		a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor activates some activity of the receptor
http://purl.obolibrary.org/obo/RO_0018028	is inverse agonist of	http://purl.obolibrary.org/obo/RO_0002449	directly negatively regulates activity of		a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor inhibits some activity of the receptor to below basal level
http://purl.obolibrary.org/obo/RO_0018029	is antagonist of	http://purl.obolibrary.org/obo/RO_0002449	directly negatively regulates activity of		a relation between a ligand (material entity) and a receptor (material entity) that implies the binding of the ligand to the receptor reduces some activity of the receptor to basal level
http://purl.obolibrary.org/obo/RO_0002802	reservoir host of	http://purl.obolibrary.org/obo/RO_0002453	host of		A relation between a host organism and a hosted organism in which the hosted organism naturally occurs in an indefinitely maintained reservoir provided by the host.
http://purl.obolibrary.org/obo/RO_0002803	has reservoir host	http://purl.obolibrary.org/obo/RO_0002454	has host		inverse of reservoir host of
http://purl.obolibrary.org/obo/RO_0012013	positively regulates in another organism	http://purl.obolibrary.org/obo/RO_0002010	regulates in another organism		x 'positively regulates in other organism' y if and only if: (x is the realization of a function to increase the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).
http://purl.obolibrary.org/obo/RO_0012014	negatively regulates in another organism	http://purl.obolibrary.org/obo/RO_0002010	regulates in another organism		x 'negatively regulates in other organism' y if and only if: (x is the realization of a function to reduce the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).
http://purl.obolibrary.org/obo/RO_0020101	vessel supplies blood to	http://purl.obolibrary.org/obo/RO_0002178	supplies		x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y.
http://purl.obolibrary.org/obo/RO_0020102	vessel drains blood from	http://purl.obolibrary.org/obo/RO_0002179	drains		x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y.
http://purl.obolibrary.org/obo/RO_0020103	directly supplies and drains	http://purl.obolibrary.org/obo/RO_0002179	drains		x directly supplies and drains y if and only if x is a capillary, y is an anatomical entity, and x directly supplies and drains y.
http://purl.obolibrary.org/obo/RO_0002103	synapsed by	http://purl.obolibrary.org/obo/RO_0002485	receives input from		Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. 
http://purl.obolibrary.org/obo/RO_0002120	synapsed to	http://purl.obolibrary.org/obo/RO_0002486	sends output to		 Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to.
        
http://purl.obolibrary.org/obo/RO_0002255	developmentally contributes to	http://purl.obolibrary.org/obo/RO_0002385	has potential to developmentally contribute to		inverse of has developmental contribution from
http://purl.obolibrary.org/obo/RO_0002334	regulated by	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of regulates
http://purl.obolibrary.org/obo/RO_0002335	negatively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of negatively regulates
http://purl.obolibrary.org/obo/RO_0002336	positively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of positively regulates
http://purl.obolibrary.org/obo/RO_0002379	spatially coextensive with	http://purl.obolibrary.org/obo/RO_0002131	overlaps		x spatially_coextensive_with y if and inly if x and y have the same location
http://purl.obolibrary.org/obo/RO_0002385	has potential to developmentally contribute to	http://purl.obolibrary.org/obo/RO_0002384	has developmental potential involving		x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y
http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes		inverse of causally upstream of or within
http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		A relationship between a material entity and a process where the material entity has some causal role that influences the process
http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	http://purl.obolibrary.org/obo/RO_0002410	causally related to		p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q.
http://purl.obolibrary.org/obo/RO_0002584	has part structure that is capable of	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
http://purl.obolibrary.org/obo/RO_0002596	capable of regulating	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		Holds between c and p if and only if c is capable of some activity a, and a regulates p.
http://purl.obolibrary.org/obo/RO_0002597	capable of negatively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
http://purl.obolibrary.org/obo/RO_0002598	capable of positively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
http://purl.obolibrary.org/obo/RO_0002608	process has causal agent	http://purl.obolibrary.org/obo/RO_0002410	causally related to		Inverse of 'causal agent in process'
http://purl.obolibrary.org/obo/RO_0002015	has positive regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
http://purl.obolibrary.org/obo/RO_0002014	has negative regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
http://purl.obolibrary.org/obo/RO_0013008	receives synaptic input from neuron	http://purl.obolibrary.org/obo/RO_0002103	synapsed by		A relationship between an anatomical structure (including cells) and a neuron that has a functionally relevant number of chemical synapses to it.
http://purl.obolibrary.org/obo/RO_0020326	provides clinical information for	http://purl.obolibrary.org/obo/RO_0002607	is marker for		A relationship between a biomarker 'b' and a disease or condition of clinical interest 'd', where the presence or occurrence of 'b' provides clinical information about 'd'.
http://purl.obolibrary.org/obo/RO_0020327	diagnostic for	http://purl.obolibrary.org/obo/RO_0020326	provides clinical information for		A relationship between a biomarker 'b' and a disease or condition of clinical interest 'd', where the presence or occurrence of 'b' is used to infer the presence or occurrence of 'd' or determine its subtype.
http://purl.obolibrary.org/obo/RO_0020328	monitors status of	http://purl.obolibrary.org/obo/RO_0020326	provides clinical information for		A relationship between a serially-measured biomarker 'b' and a disease or condition of clinical interest 'd', where 'b' is used to infer the status of 'd'.
http://purl.obolibrary.org/obo/RO_0020329	indicates response to	http://purl.obolibrary.org/obo/RO_0020334	indicates clinical effect of		A relationship between a biomarker 'b' and an exposure agent 'e', where 'b' is used to show that a biological response to 'e' has occurred.
http://purl.obolibrary.org/obo/RO_0020334	indicates clinical effect of	http://purl.obolibrary.org/obo/RO_0002607	is marker for		A relationship between a biomarker 'b' and an exposure agent 'e', where the effect of exposure to 'e' is correlated with the presence or occurrence of 'b', and the observation of 'b' is used to infer exposure to 'e'.
http://purl.obolibrary.org/obo/RO_0020330	predicts effect of	http://purl.obolibrary.org/obo/RO_0020334	indicates clinical effect of		A relationship between a biomarker 'b' and an exposure agent 'e', where 'b' is used to identify individuals who are likely to experience a favorable or unfavorable effect from exposure to 'e'.
http://purl.obolibrary.org/obo/RO_0020331	prognostic for	http://purl.obolibrary.org/obo/RO_0020326	provides clinical information for		A relationship between a biomarker 'b' and a disease or condition of clinical interest 'd', where the presence or occurrence of 'b' is used to infer the likelihood of a clinical event, disease recurrence or progression in patients who have 'd'.
http://purl.obolibrary.org/obo/RO_0020333	indicates risk of developing	http://purl.obolibrary.org/obo/RO_0020326	provides clinical information for		A relationship between a biomarker 'b' and a disease or condition of clinical interest 'd', where the presence or occurrence of 'b' is used to infer the potential for developing 'd' in an individual that currently does not have 'd'.
http://purl.obolibrary.org/obo/RO_0020335	monitors effect of	http://purl.obolibrary.org/obo/RO_0020334	indicates clinical effect of		A relationship between a serially-measured biomarker 'b' and an exposure agent 'e', where 'b' is used to provide evidence of a biological effect of 'e'.
http://purl.obolibrary.org/obo/RO_0020336	monitors exposure to	http://purl.obolibrary.org/obo/RO_0020334	indicates clinical effect of		A relationship between a serially-measured biomarker 'b' and an exposure agent 'e', where 'b' is used to provide evidence of exposure to 'e'.
http://purl.obolibrary.org/obo/RO_0002082	simultaneous with	http://purl.obolibrary.org/obo/RO_0002081	before or simultaneous with		x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time.
http://purl.obolibrary.org/obo/RO_0002102	axon synapses in	http://purl.obolibrary.org/obo/RO_0002113	has presynaptic terminal in		Relation between a neuron and some structure its axon forms (chemical) synapses in.
http://purl.obolibrary.org/obo/RO_0002121	dendrite synapsed in	http://purl.obolibrary.org/obo/RO_0002110	has postsynaptic terminal in		Relation between a neuron and some structure  (e.g.- a brain region) in which its dendrite receives synaptic input.

	
http://purl.obolibrary.org/obo/RO_0002157	has derived by descendant	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to		inverse of derived by descent from
http://purl.obolibrary.org/obo/RO_0002158	shares ancestor with	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to		two individual entities d1 and d2 stand in a shares_ancestor_with relation if and only if there exists some a such that d1 derived_by_descent_from a and d2 derived_by_descent_from a.
http://purl.obolibrary.org/obo/RO_0002204	gene product of	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		definition "x has gene product of y if and only if y is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from x"
http://purl.obolibrary.org/obo/RO_0002205	has gene product	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		x has gene product y if and only if x is a gene (SO:0000704) that participates in some gene expression process (GO:0010467) where the output of that process is either y or something that is ribosomally translated from y
http://purl.obolibrary.org/obo/RO_0002206	expressed in	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process
http://purl.obolibrary.org/obo/RO_0002207	directly develops from	http://purl.obolibrary.org/obo/RO_0002202	develops from		Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y.
http://purl.obolibrary.org/obo/RO_0002221	surrounds	http://purl.obolibrary.org/obo/RO_0002220	adjacent to		inverse of surrounded by
http://purl.obolibrary.org/obo/RO_0002225	develops from part of	http://purl.obolibrary.org/obo/RO_0002202	develops from		x develops from part of y if and only if there exists some z such that x develops from z and z is part of y
http://purl.obolibrary.org/obo/RO_0002226	develops in	http://purl.obolibrary.org/obo/RO_0002258	developmentally preceded by		x develops_in y if x is located in y whilst x is developing
http://purl.obolibrary.org/obo/RO_0002229	ends	http://purl.obolibrary.org/obo/BFO_0000050	part of		inverse of ends with
http://purl.obolibrary.org/obo/RO_0002257	developmentally induces	http://purl.obolibrary.org/obo/RO_0002386	has potential to developmentally induce		Inverse of developmentally induced by
http://purl.obolibrary.org/obo/RO_0002291	ubiquitously expressed in	http://purl.obolibrary.org/obo/RO_0002206	expressed in		x is ubiquitously expressed in y if and only if x is expressed in y, and the majority of cells in y express x
http://purl.obolibrary.org/obo/RO_0002292	expresses	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process.
http://purl.obolibrary.org/obo/RO_0002293	ubiquitously expresses	http://purl.obolibrary.org/obo/RO_0002292	expresses		inverse of ubiquiotously expressed in
http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of	http://purl.obolibrary.org/obo/RO_0002324	developmentally related to		p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss).
http://purl.obolibrary.org/obo/RO_0002296	results in development of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state.
http://purl.obolibrary.org/obo/RO_0002298	results in morphogenesis of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state.
http://purl.obolibrary.org/obo/RO_0002299	results in maturation of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity.
http://purl.obolibrary.org/obo/RO_0009501	realized in response to	http://purl.obolibrary.org/obo/RO_0002410	causally related to		r 'realized in response to' s iff, r is a realizable (e.g. a plant trait such as responsivity to drought), s is an environmental stimulus (a process), and s directly causes the realization of r.
http://purl.obolibrary.org/obo/RO_0004026	disease has location	http://purl.obolibrary.org/obo/RO_0040035	disease relationship		A relationship between a disease and an anatomical entity where the disease has one or more features that are located in that entity.
http://purl.obolibrary.org/obo/RO_0015003	subcluster of	http://purl.obolibrary.org/obo/BFO_0000050	part of		A relation between a group and another group it is part of but does not fully constitute.
http://purl.obolibrary.org/obo/RO_0015015	has high plasma membrane amount	http://purl.obolibrary.org/obo/RO_0002104	has plasma membrane part		A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface.
http://purl.obolibrary.org/obo/RO_0015016	has low plasma membrane amount	http://purl.obolibrary.org/obo/RO_0002104	has plasma membrane part		A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface.
http://purl.obolibrary.org/obo/RO_0016004	has exposure medium	http://purl.obolibrary.org/obo/RO_0002244	related via exposure to		X has exposure medium Y if X is an exposure event (process), Y is a material entity, and the stimulus for X is transmitted or carried in Y.
http://purl.obolibrary.org/obo/RO_0018001	is myristoyltransferase activity	http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property		Helper relation for OWL definition of RO:0018002 myristoylates
http://purl.obolibrary.org/obo/RO_0018002	myristoylates	http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with		A molecularly-interacts-with relationship between two entities, where the subject catalyzes a myristoylation activity that takes the object as input
http://purl.obolibrary.org/obo/RO_0012009	constitutively upstream of	http://purl.obolibrary.org/obo/RO_0002304	causally upstream of, positive effect		p is constitutively upstream of q iff p is causally upstream of q, p is required for execution of q or a part of q, and the execution of p is approximately constant.
http://purl.obolibrary.org/obo/RO_0012010	removes input for	http://purl.obolibrary.org/obo/RO_0002305	causally upstream of, negative effect		p removes input for q iff p is causally upstream of q, there exists some c such that p has_input c and q has_input c, p reduces the levels of c, and c is rate limiting for execution of q.
http://purl.obolibrary.org/obo/RO_0012007	results in adhesion of	http://purl.obolibrary.org/obo/RO_0040036	results in changes to anatomical or cellular structure		The relationship that links anatomical entities with a process that results in the adhesion of two or more entities via the non-covalent interaction of molecules expressed in, located in, and/or adjacent to, those entities.
http://purl.obolibrary.org/obo/RO_0013007	has sensory dendrite in	http://purl.obolibrary.org/obo/RO_0002360	has dendrite location		Relation between a sensory neuron and some structure in which it receives sensory input via a sensory dendrite.
http://purl.obolibrary.org/obo/RO_0014001	disease has infectious agent	http://purl.obolibrary.org/obo/RO_0004019	disease has basis in		A relationship between a disease and an infectious agent where the material basis of the disease is an infection with some infectious agent.
http://purl.obolibrary.org/obo/RO_0002238	has component participant	http://purl.obolibrary.org/obo/RO_0000057	has participant		X 'has component participant' Y means X 'has participant' Y and there is a cardinality constraint that specifies the numbers of Ys.
http://purl.obolibrary.org/obo/RO_0002009	cell expresses	http://purl.obolibrary.org/obo/RO_0002292	expresses		A relation that applies between a cell(c) and a gene(g) , where the process of 'transcription, DNA templated (GO_0006351)' is occuring in in cell c and that process has input gene g.
http://purl.obolibrary.org/obo/RO_0002010	regulates in another organism	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		x 'regulates in other organism' y if and only if: (x is the realization of a function to exert an effect on the frequency, rate or extent of y) AND (the agents of x are produced by organism o1 and the agents of y are produced by organism o2).
http://purl.obolibrary.org/obo/RO_0002227	obligate parasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A sub-relation of parasite-of in which the parasite that cannot complete its life cycle without a host.
http://purl.obolibrary.org/obo/RO_0002228	facultative parasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A sub-relations of parasite-of in which the parasite that can complete its life cycle independent of a host.
http://purl.obolibrary.org/obo/RO_0002315	results in acquisition of features of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity
http://purl.obolibrary.org/obo/RO_0002325	colocalizes with	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		a colocalizes_with b if and only if  a is transiently or peripherally associated with b[GO].
http://purl.obolibrary.org/obo/RO_0002332	regulates levels of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		p regulates levels of c if p regulates some amount (PATO:0000070) of c
http://purl.obolibrary.org/obo/RO_0002338	has target start location	http://purl.obolibrary.org/obo/RO_0002344	results in transport to from or in		This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination.
http://purl.obolibrary.org/obo/RO_0002339	has target end location	http://purl.obolibrary.org/obo/RO_0002344	results in transport to from or in		This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l.
http://purl.obolibrary.org/obo/RO_0002340	imports	http://purl.obolibrary.org/obo/RO_0002020	transports		Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the start location of c is part of the region that surrounds s.
http://purl.obolibrary.org/obo/RO_0002341	results in transport along	http://purl.obolibrary.org/obo/RO_0002337	related via localization to		Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l 
http://purl.obolibrary.org/obo/RO_0002342	results in transport across	http://purl.obolibrary.org/obo/RO_0002344	results in transport to from or in		Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m.
http://purl.obolibrary.org/obo/RO_0002345	exports	http://purl.obolibrary.org/obo/RO_0002020	transports		Holds between p and c when p is a transportation or localization process and the outcome of this process is to move c to a destination that is part of some s, where the end location of c is part of the region that surrounds s.
http://purl.obolibrary.org/obo/RO_0002348	results in commitment to	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		p 'results in commitment to' c if and only if p is a developmental process and c is a cell and p results in the state of c changing such that is can only develop into a single cell type.
http://purl.obolibrary.org/obo/RO_0002349	results in determination of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		p 'results in determination of' c if and only if p is a developmental process and c is a cell and p results in the state of c changing to be determined. Once a cell becomes determined, it becomes committed to differentiate down a particular pathway regardless of its environment.
http://purl.obolibrary.org/obo/RO_0002355	results in structural organization of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		A relationship between a process and an anatomical entity such that the process contributes to the act of creating the structural organization of the anatomical entity.
http://purl.obolibrary.org/obo/RO_0002356	results in specification of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		The relationship linking a cell and its participation in a process that results in the fate of the cell being specified. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. 
http://purl.obolibrary.org/obo/RO_0002357	results in developmental induction of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		p results in developmental induction of c if and only if p is a collection of cell-cell signaling processes that signal to a neighbouring tissue that is the precursor of the mature c, where the signaling results in the commitment to cell types necessary for the formation of c.
http://purl.obolibrary.org/obo/RO_0002381	main stem of	http://purl.obolibrary.org/obo/RO_0002375	in branching relationship with		x main_stem_of y if y is a branching structure and x is a channel that traces a linear path through y, such that x has higher capacity than any other such path.
http://purl.obolibrary.org/obo/RO_0002382	proper distributary of	http://purl.obolibrary.org/obo/RO_0002377	distributary of		x proper_distributary_of y iff x distributary_of y and x does not flow back into y
http://purl.obolibrary.org/obo/RO_0002383	proper tributary of	http://purl.obolibrary.org/obo/RO_0002376	tributary of		x proper_tributary_of y iff x tributary_of y and x does not originate from y
http://purl.obolibrary.org/obo/RO_0002386	has potential to developmentally induce	http://purl.obolibrary.org/obo/RO_0002384	has developmental potential involving		x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y
http://purl.obolibrary.org/obo/RO_0002414	transitively provides input for	http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect		transitive form of directly_provides_input_for
http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of		c involved in regulation of p if c is involved in some p' and p' regulates some p
http://purl.obolibrary.org/obo/RO_0002429	involved in positive regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' positively regulates some p
http://purl.obolibrary.org/obo/RO_0002430	involved in negative regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		A biotic interaction in which the two organisms live together in more or less intimate association.
http://purl.obolibrary.org/obo/RO_0002441	commensually interacts with	http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with		An interaction relationship between two organisms living together in more or less intimate association in a relationship in which one benefits and the other is unaffected (GO).
http://purl.obolibrary.org/obo/RO_0002442	mutualistically interacts with	http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with		An interaction relationship between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other (GO).
http://purl.obolibrary.org/obo/RO_0002443	interacts with via parasite-host interaction	http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with		An interaction relationship between two organisms living together in more or less intimate association in a relationship in which association is disadvantageous or destructive to one of the organisms (GO).
http://purl.obolibrary.org/obo/RO_0002446	participates in a abiotic-biotic interaction with	http://purl.obolibrary.org/obo/RO_0002437	biotically interacts with		A biotic interaction relationship in which one partner is an organism and the other partner is inorganic. For example, the relationship between a sponge and the substrate to which is it anchored.
http://purl.obolibrary.org/obo/RO_0002452	has symptom	http://purl.obolibrary.org/obo/RO_0002200	has phenotype		A relation that holds between a disease or an organism and a phenotype
http://purl.obolibrary.org/obo/RO_0002454	has host	http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with		X 'has host' y if and only if: x is an organism, y is an organism, and x can live on the surface of or within the body of y
http://purl.obolibrary.org/obo/RO_0002472	is evidence for	http://purl.obolibrary.org/obo/RO_0002616	related via evidence or inference to		A relationship between a piece of evidence a and some entity b, where b is  an information content entity, material entity or process, and 
the a supports either the existence of b, or the truth value of b.
http://purl.obolibrary.org/obo/RO_0002480	ubiquitinates	http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with		An interaction relation between x and y in which x catalyzes a reaction in which one or more ubiquitin groups are added to y
http://purl.obolibrary.org/obo/RO_0002508	determines	http://purl.obolibrary.org/obo/RO_0002566	causally influences		inverse of determined by
http://purl.obolibrary.org/obo/RO_0002509	determined by part of	http://purl.obolibrary.org/obo/RO_0002131	overlaps		s 'determined by part of' w if and only if there exists some f such that (1) s 'determined by' f and (2) f part_of w, or f=w.
http://purl.obolibrary.org/obo/RO_0002510	transcribed from	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		x is transcribed from y if and only if x is synthesized from template y
http://purl.obolibrary.org/obo/RO_0002511	transcribed to	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		inverse of transcribed from
http://purl.obolibrary.org/obo/RO_0002512	ribosomal translation of	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		x is the ribosomal translation of y if and only if a ribosome reads x through a series of triplet codon-amino acid adaptor activities (GO:0030533) and produces y
http://purl.obolibrary.org/obo/RO_0002513	ribosomally translates to	http://purl.obolibrary.org/obo/RO_0002330	genomically related to		inverse of ribosomal translation of
http://purl.obolibrary.org/obo/RO_0002515	sequentially adjacent to	http://purl.obolibrary.org/obo/RO_0002527	does not overlap sequence of		x is sequentially adjacent to y iff x and y do not overlap and if there are no base units intervening between x and y
http://purl.obolibrary.org/obo/RO_0002520	is consecutive sequence of	http://purl.obolibrary.org/obo/RO_0002524	has subsequence		x is a consecutive sequence of y iff x has subsequence y, and all the parts of x are made of zero or more repetitions of y or sequences as the same type as y.
http://purl.obolibrary.org/obo/RO_0002521	is sequentially aligned with	http://purl.obolibrary.org/obo/RO_0002514	sequentially related to		x is sequentially aligned with if a significant portion bases of x and y correspond in terms of their base type and their relative ordering
http://purl.obolibrary.org/obo/RO_0002522	bounds sequence of	http://purl.obolibrary.org/obo/RO_0002514	sequentially related to		x bounds the sequence of y iff the upstream-most part of x is upstream of or coincident with the upstream-most part of y, and the downstream-most part of x is downstream of or coincident with the downstream-most part of y
http://purl.obolibrary.org/obo/RO_0002523	is bound by sequence of	http://purl.obolibrary.org/obo/RO_0002514	sequentially related to		inverse of bounds sequence of
http://purl.obolibrary.org/obo/RO_0002526	overlaps sequence of	http://purl.obolibrary.org/obo/RO_0002514	sequentially related to		x overlaps the sequence of y if and only if x has a subsequence z and z is a subsequence of y.
http://purl.obolibrary.org/obo/RO_0002528	is upstream of sequence of	http://purl.obolibrary.org/obo/RO_0002527	does not overlap sequence of		inverse of downstream of sequence of
http://purl.obolibrary.org/obo/RO_0002529	is downstream of sequence of	http://purl.obolibrary.org/obo/RO_0002527	does not overlap sequence of		x is downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, or (2) x and y are sequence units, and x is either immediately downstream of y, or transitively downstream of y.
http://purl.obolibrary.org/obo/RO_0002530	is immediately downstream of sequence of	http://purl.obolibrary.org/obo/RO_0002529	is downstream of sequence of		x is immediately downstream of the sequence of y iff either (1) x and y have sequence units, and all units of x are downstream of all units of y, and x is sequentially adjacent to y, or (2) x and y are sequence units, in which case the immediately downstream relation is primitive and defined by context: for DNA bases, y would be adjacent and 5' to y
http://purl.obolibrary.org/obo/RO_0002531	is immediately upstream of sequence of	http://purl.obolibrary.org/obo/RO_0002528	is upstream of sequence of		inverse of immediately downstream of
http://purl.obolibrary.org/obo/RO_0002552	results in ending of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		p results in the end of s if p results in a change of state in s whereby s either ceases to exist, or s becomes functionally impaired or s has its fate committed such that it is put on a path to be degraded.
http://purl.obolibrary.org/obo/RO_0002553	hyperparasite of	http://purl.obolibrary.org/obo/RO_0002454	has host		x is a hyperparasite of y iff x is a parasite of a parasite of the target organism y
http://purl.obolibrary.org/obo/RO_0002554	hyperparasitized by	http://purl.obolibrary.org/obo/RO_0002453	host of		inverse of hyperparasite of
http://purl.obolibrary.org/obo/RO_0002555	allelopath of	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		A relationship between organisms where one organism is influenced by the biochemicals produced by another.
http://purl.obolibrary.org/obo/RO_0002556	pathogen of	http://purl.obolibrary.org/obo/RO_0002454	has host		Inverse of has pathogen
http://purl.obolibrary.org/obo/RO_0002557	has pathogen	http://purl.obolibrary.org/obo/RO_0002453	host of		A host interaction where the smaller of the two members of a symbiosis causes a disease in the larger member
http://purl.obolibrary.org/obo/RO_0002558	has evidence	http://purl.obolibrary.org/obo/RO_0002616	related via evidence or inference to		inverse of is evidence for
http://purl.obolibrary.org/obo/RO_0002565	results in movement of	http://purl.obolibrary.org/obo/RO_0040036	results in changes to anatomical or cellular structure		Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c
http://purl.obolibrary.org/obo/RO_0002570	conduit for	http://purl.obolibrary.org/obo/RO_0002131	overlaps		x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x.
http://purl.obolibrary.org/obo/RO_0002578	directly regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		p directly regulates q iff p is immediately causally upstream of q and p regulates q.
http://purl.obolibrary.org/obo/RO_0002583	existence starts at end of	http://purl.obolibrary.org/obo/RO_0002496	existence starts during or after		holds between x and y if and only if the time point at which x starts is equivalent to the time point at which y ends. Formally: iff α(x) = ω(y).
http://purl.obolibrary.org/obo/RO_0002586	results in breakdown of	http://purl.obolibrary.org/obo/RO_0002233	has input		p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p
http://purl.obolibrary.org/obo/RO_0002589	results in catabolism of	http://purl.obolibrary.org/obo/RO_0002586	results in breakdown of		p results in catabolism of c if and only if p is a catabolic process, and the execution of p results in c being broken into smaller parts with energy being released.
http://purl.obolibrary.org/obo/RO_0002592	results in organization of	http://purl.obolibrary.org/obo/RO_0040036	results in changes to anatomical or cellular structure		p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c
http://purl.obolibrary.org/obo/RO_0002593	existence ends at start of	http://purl.obolibrary.org/obo/RO_0002497	existence ends during or before		holds between x and y if and only if the time point at which x ends is equivalent to the time point at which y starts. Formally: iff ω(x) = α(y).
http://purl.obolibrary.org/obo/RO_0002607	is marker for	http://purl.obolibrary.org/obo/RO_0002610	correlated with		c is marker for d iff the presence or occurrence of d is correlated with the presence of occurrence of c, and the observation of c is used to infer the presence or occurrence of d. Note that this does not imply that c and d are in a direct causal relationship, as it may be the case that there is a third entity e that stands in a direct causal relationship with c and d.
http://purl.obolibrary.org/obo/RO_0002614	is evidence with support from	http://purl.obolibrary.org/obo/RO_0002616	related via evidence or inference to		A relationship between a piece of evidence and an entity that plays a role in supporting that evidence.
http://purl.obolibrary.org/obo/RO_0002629	directly positively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q.
http://purl.obolibrary.org/obo/RO_0002630	directly negatively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.
http://purl.obolibrary.org/obo/RO_0002632	ectoparasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A sub-relation of parasite-of in which the parasite lives on or in the integumental system of the host
http://purl.obolibrary.org/obo/RO_0002633	has ectoparasite	http://purl.obolibrary.org/obo/RO_0002445	parasitized by		inverse of ectoparasite of
http://purl.obolibrary.org/obo/RO_0002636	mesoparasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		A sub-relation of parasite-of in which the parasite is partially an endoparasite and partially an ectoparasite
http://purl.obolibrary.org/obo/RO_0002637	has mesoparasite	http://purl.obolibrary.org/obo/RO_0002445	parasitized by		inverse of mesoparasite of
http://purl.obolibrary.org/obo/RO_0002638	intercellular endoparasite of	http://purl.obolibrary.org/obo/RO_0002634	endoparasite of		A sub-relation of endoparasite-of in which the parasite inhabits the spaces between host cells.
http://purl.obolibrary.org/obo/RO_0002639	has intercellular endoparasite	http://purl.obolibrary.org/obo/RO_0002635	has endoparasite		inverse of intercellular endoparasite of
http://purl.obolibrary.org/obo/RO_0002640	intracellular endoparasite of	http://purl.obolibrary.org/obo/RO_0002634	endoparasite of		A sub-relation of endoparasite-of in which the parasite inhabits host cells.
http://purl.obolibrary.org/obo/RO_0002641	has intracellular endoparasite	http://purl.obolibrary.org/obo/RO_0002635	has endoparasite		inverse of intracellular endoparasite of
http://purl.obolibrary.org/obo/RO_0003002	represses expression of	http://purl.obolibrary.org/obo/RO_0002449	directly negatively regulates activity of		Holds between entity A (a transcription factor) and a nucleic acid B if and only if A down-regulates the expression of B. The nucleic acid can be a gene or an mRNA.
http://purl.obolibrary.org/obo/RO_0003003	increases expression of	http://purl.obolibrary.org/obo/RO_0002450	directly positively regulates activity of		Holds between entity A (a transcription factor) and nucleic acid B if and only if A up-regulates the expression of B. The nucleic acid can be a gene or mRNA.
http://purl.obolibrary.org/obo/RO_0002081	before or simultaneous with	http://purl.obolibrary.org/obo/RO_0002222	temporally related to	<=	
http://purl.obolibrary.org/obo/RO_0002322	confers advantage in	http://purl.obolibrary.org/obo/RO_0002321	ecologically related to	adapted for	
http://purl.obolibrary.org/obo/RO_0002087	immediately preceded by	http://purl.obolibrary.org/obo/BFO_0000062	preceded by	starts_at_end_of	
http://purl.obolibrary.org/obo/RO_0002090	immediately precedes	http://purl.obolibrary.org/obo/BFO_0000063	precedes	meets	
http://purl.obolibrary.org/obo/RO_0002091	starts during	http://purl.obolibrary.org/obo/RO_0002222	temporally related to	io	
http://purl.obolibrary.org/obo/RO_0002092	happens during	http://purl.obolibrary.org/obo/RO_0002093	ends during	during	
http://purl.obolibrary.org/obo/RO_0002093	ends during	http://purl.obolibrary.org/obo/RO_0002222	temporally related to	overlaps	
http://purl.obolibrary.org/obo/RO_0002085	encompasses	http://purl.obolibrary.org/obo/RO_0002088	during which starts	di	
http://purl.obolibrary.org/obo/RO_0002447	phosphorylates	http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.	
http://purl.obolibrary.org/obo/RO_0002455	pollinates	http://purl.obolibrary.org/obo/RO_0002442	mutualistically interacts with	is subject of pollination interaction with	
http://purl.obolibrary.org/obo/RO_0002456	pollinated by	http://purl.obolibrary.org/obo/RO_0002442	mutualistically interacts with	is target of pollination interaction with	
http://purl.obolibrary.org/obo/RO_0002083	before	http://purl.obolibrary.org/obo/RO_0002081	before or simultaneous with		
http://purl.obolibrary.org/obo/RO_0002343	results in growth of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		
http://purl.obolibrary.org/obo/RO_0002585	results in closure of	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		
http://purl.obolibrary.org/obo/RO_0002297	results in formation of anatomical entity	http://purl.obolibrary.org/obo/RO_0002295	results in developmental progression of		
http://purl.obolibrary.org/obo/RO_0002287	part of developmental precursor of	http://purl.obolibrary.org/obo/RO_0002286	developmentally succeeded by		
http://purl.obolibrary.org/obo/RO_0002159	serially homologous to	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to		
http://purl.obolibrary.org/obo/RO_0002312	evolutionary variant of	http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to		
http://purl.obolibrary.org/obo/RO_0002461	partner in	http://purl.obolibrary.org/obo/RO_0000056	participates in		
http://purl.obolibrary.org/obo/RO_0002405	immediately causally downstream of	http://purl.obolibrary.org/obo/RO_0002404	causally downstream of		
http://purl.obolibrary.org/obo/RO_0002017	has component activity	http://purl.obolibrary.org/obo/RO_0002018	has component process		
http://purl.obolibrary.org/obo/IAO_0000039	has measurement unit label	http://purl.obolibrary.org/obo/BFO_0000051	has part		
http://purl.obolibrary.org/obo/IAO_0000407	has coordinate unit label	http://purl.obolibrary.org/obo/BFO_0000051	has part		
http://purl.obolibrary.org/obo/RO_0002435	genetically interacts with	http://purl.obolibrary.org/obo/RO_0002434	interacts with		
http://purl.obolibrary.org/obo/RO_0002559	causally influenced by	http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities		
http://purl.obolibrary.org/obo/RO_0002425	differs in attribute of	http://purl.obolibrary.org/obo/RO_0002424	differs in		
http://purl.obolibrary.org/obo/RO_0002426	differs in attribute	http://purl.obolibrary.org/obo/RO_0002424	differs in		
http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)		
http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002465	is symbiosis	http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002481	is kinase activity	http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002482	is ubiquitination	http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002006	has synaptic terminal of	http://purl.obolibrary.org/obo/RO_0002131	overlaps		
http://purl.obolibrary.org/obo/RO_0002360	has dendrite location	http://purl.obolibrary.org/obo/RO_0002131	overlaps		
http://purl.obolibrary.org/obo/RO_0002089	starts before	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		
http://purl.obolibrary.org/obo/RO_0002086	ends after	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		
http://purl.obolibrary.org/obo/RO_0002084	during which ends	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		
http://purl.obolibrary.org/obo/RO_0002088	during which starts	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		
http://purl.obolibrary.org/obo/RO_0002591	results in remodeling of	http://purl.obolibrary.org/obo/RO_0002592	results in organization of		
http://purl.obolibrary.org/obo/RO_0002354	formed as result of	http://purl.obolibrary.org/obo/RO_0002353	output of		
http://purl.obolibrary.org/obo/RO_0002485	receives input from	http://purl.obolibrary.org/obo/RO_0002170	connected to		
http://purl.obolibrary.org/obo/RO_0002486	sends output to	http://purl.obolibrary.org/obo/RO_0002170	connected to		
http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with	http://purl.obolibrary.org/obo/RO_0002437	biotically interacts with		
http://purl.obolibrary.org/obo/RO_0002459	is vector for	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		
http://purl.obolibrary.org/obo/RO_0002460	has vector	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		
http://purl.obolibrary.org/obo/RO_0002618	visits	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		
http://purl.obolibrary.org/obo/RO_0002619	visited by	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		
http://purl.obolibrary.org/obo/RO_0002626	kills	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		
http://purl.obolibrary.org/obo/RO_0002627	is killed by	http://purl.obolibrary.org/obo/RO_0002574	participates in a biotic-biotic interaction with		
http://purl.obolibrary.org/obo/RO_0004001	has material basis in gain of function germline mutation in	http://purl.obolibrary.org/obo/RO_0004000	condition has genetic basis in		
http://purl.obolibrary.org/obo/RO_0004002	has material basis in loss of function germline mutation in	http://purl.obolibrary.org/obo/RO_0004000	condition has genetic basis in		
http://purl.obolibrary.org/obo/RO_0004003	has material basis in germline mutation in	http://purl.obolibrary.org/obo/RO_0004000	condition has genetic basis in		
http://purl.obolibrary.org/obo/RO_0004004	has material basis in somatic mutation in	http://purl.obolibrary.org/obo/RO_0004000	condition has genetic basis in		
http://purl.obolibrary.org/obo/RO_0004005	has major susceptibility factor	http://purl.obolibrary.org/obo/RO_0004000	condition has genetic basis in		
http://purl.obolibrary.org/obo/RO_0004006	has partial material basis in germline mutation in	http://purl.obolibrary.org/obo/RO_0004000	condition has genetic basis in		
http://purl.obolibrary.org/obo/RO_0004019	disease has basis in	http://purl.obolibrary.org/obo/RO_0004023	causal relationship with disease as subject		
http://purl.obolibrary.org/obo/RO_0004010	is genetic basis for condition	http://purl.obolibrary.org/obo/RO_0004018	is basis for realizable		
http://purl.obolibrary.org/obo/RO_0004025	disease causes dysfunction of	http://purl.obolibrary.org/obo/RO_0004023	causal relationship with disease as subject		
http://purl.obolibrary.org/obo/RO_0002326	contributes to	http://purl.obolibrary.org/obo/RO_0002329	part of structure that is capable of		
http://purl.obolibrary.org/obo/RO_0002022	directly regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		
http://purl.obolibrary.org/obo/RO_0002016	has necessary component activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		
http://purl.obolibrary.org/obo/RO_0002506	causal relation between entities	http://purl.obolibrary.org/obo/RO_0002410	causally related to		
http://purl.obolibrary.org/obo/RO_0004000	condition has genetic basis in	http://purl.obolibrary.org/obo/RO_0002410	causally related to		
http://purl.obolibrary.org/obo/RO_0004017	realizable has basis in	http://purl.obolibrary.org/obo/RO_0002410	causally related to		
http://purl.obolibrary.org/obo/RO_0004018	is basis for realizable	http://purl.obolibrary.org/obo/RO_0002410	causally related to		
http://purl.obolibrary.org/obo/RO_0004023	causal relationship with disease as subject	http://purl.obolibrary.org/obo/RO_0040035	disease relationship		
http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://purl.obolibrary.org/obo/RO_0002587	results in synthesis of	http://purl.obolibrary.org/obo/RO_0002297	results in formation of anatomical entity		
http://purl.obolibrary.org/obo/RO_0002588	results in assembly of	http://purl.obolibrary.org/obo/RO_0002592	results in organization of		
http://purl.obolibrary.org/obo/RO_0002344	results in transport to from or in	http://purl.obolibrary.org/obo/RO_0002337	related via localization to		
http://purl.obolibrary.org/obo/RO_0002453	host of	http://purl.obolibrary.org/obo/RO_0002440	symbiotically interacts with		
http://purl.obolibrary.org/obo/RO_0002624	lays eggs in	http://purl.obolibrary.org/obo/RO_0002618	visits		
http://purl.obolibrary.org/obo/RO_0002634	endoparasite of	http://purl.obolibrary.org/obo/RO_0002444	parasite of		
http://purl.obolibrary.org/obo/RO_0002625	has eggs laid in by	http://purl.obolibrary.org/obo/RO_0002619	visited by		
http://purl.obolibrary.org/obo/RO_0002635	has endoparasite	http://purl.obolibrary.org/obo/RO_0002445	parasitized by		
http://purl.obolibrary.org/obo/RO_0002462	subject participant in	http://purl.obolibrary.org/obo/RO_0002461	partner in		
http://purl.obolibrary.org/obo/RO_0002463	target participant in	http://purl.obolibrary.org/obo/RO_0002461	partner in		
http://purl.obolibrary.org/obo/RO_0002466	is commensalism	http://purl.obolibrary.org/obo/RO_0002465	is symbiosis		
http://purl.obolibrary.org/obo/RO_0002467	is mutualism	http://purl.obolibrary.org/obo/RO_0002465	is symbiosis		
http://purl.obolibrary.org/obo/RO_0002468	is parasitism	http://purl.obolibrary.org/obo/RO_0002465	is symbiosis		
http://purl.obolibrary.org/obo/RO_0002300	results in disappearance of	http://purl.obolibrary.org/obo/RO_0002552	results in ending of		
http://purl.obolibrary.org/obo/RO_0002301	results in developmental regression of	http://purl.obolibrary.org/obo/RO_0002552	results in ending of		
http://purl.obolibrary.org/obo/RO_0002590	results in disassembly of	http://purl.obolibrary.org/obo/RO_0002592	results in organization of		
http://purl.obolibrary.org/obo/RO_0012008	results in fusion of	http://purl.obolibrary.org/obo/RO_0002592	results in organization of		
http://purl.obolibrary.org/obo/RO_0002622	visits flowers of	http://purl.obolibrary.org/obo/RO_0002618	visits		
http://purl.obolibrary.org/obo/RO_0002623	has flowers visited by	http://purl.obolibrary.org/obo/RO_0002619	visited by		
http://purl.obolibrary.org/obo/OBI_0000300	obsolete_is_realized_by			is_realized_as	Relation between a realizable and a process. Reciprocal relation of realizes [GOC:cjm]
http://purl.obolibrary.org/obo/OBI_0000304	is_manufactured_by			has_manufacturer	c is_manufactured_by o means that there was a process p in which c was built in which a person, or set of people or machines did the work(bore the "Manufacturer Role", and those people/and or machines were members or of directed by the organization to do this.
http://purl.obolibrary.org/obo/OBI_0000308	obsolete_realizes			is_realization_of	Relation between a process and a function, where the unfolding of the 
process requires the execution of the function. Class level: P realizes F iff: 
given any p that instantiates P, there exists some f, t such that f instantiates
 F at t and p *realizes* f. Here, *realizes* is the primitive 
instance level relation [GOC:cjm]
http://purl.obolibrary.org/obo/OBI_0000315	obsoleted_has_specified_input_information			consumes data	A relation between a process and a participant in that process, that consumes a data set . The process is the realization of a concretization of a directive information entity (objective specification or plan specification). In general, not all data present at the beginning of the process are specified_data.
http://purl.obolibrary.org/obo/OBI_0000646	provisions			supplies	A relation between an organisation or person and a material entity, where the organization or person provides or supplies the material entity for others to use
http://purl.obolibrary.org/obo/RO_0000053	has characteristic			is bearer of	Inverse of characteristic_of
http://purl.obolibrary.org/obo/RO_0000056	participates in			participates_in	a relation between a continuant and a process, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/RO_0000057	has participant			has_participant	a relation between a process and a continuant, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/RO_0001000	derives from			derives_from	a relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
http://purl.obolibrary.org/obo/RO_0001001	derives into			derives_into	a relation between two distinct material entities, the old entity and the new entity, in which the new entity begins to exist when the old entity ceases to exist, and the new entity inherits the significant portion of the matter of the old entity
http://purl.obolibrary.org/obo/RO_0001015	location of			location_of	a relation between two independent continuants, the location and the target, in which the target is entirely within the location
http://purl.obolibrary.org/obo/RO_0001025	located in			located_in	a relation between two independent continuants, the target and the location, in which the target is entirely within the location
http://purl.obolibrary.org/obo/RO_0002218	obsolete has active participant			has agent	OBSOLETE x has participant y if and only if x realizes some active role that inheres in y
http://purl.obolibrary.org/obo/RO_0003301	has role in modeling			is used to study	A relation between a biological, experimental, or computational artifact and an entity it is used to study, in virtue of its replicating or approximating features of the studied entity.
http://purl.obolibrary.org/obo/RO_0002402	obsolete has direct output			directly produces	p has direct input c iff c is a participanti n p, c is present at the end of p, and c is not present at the beginning of c. 
http://purl.obolibrary.org/obo/BFO_0000066	occurs in			unfolds_in	b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
http://purl.obolibrary.org/obo/RO_0002217	obsolete actively participates in			agent in	OBSOLETE x actively participates in y if and only if x participates in y and x realizes some active role
http://purl.obolibrary.org/obo/RO_HOM0000000	in similarity relationship with				Relation between biological objects that resemble or are related to each other sufficiently to warrant a comparison.
http://purl.obolibrary.org/obo/RO_0009004	has consumer				'has consumer' is a relation between a material entity and an organism in which the former can normally be digested or otherwise absorbed by the latter without immediate or persistent ill effect.
http://purl.obolibrary.org/obo/RO_0002320	evolutionarily related to				A relationship that holds via some environmental process
http://purl.obolibrary.org/obo/RO_0002324	developmentally related to				A relationship that holds between entities participating in some developmental process (GO:0032502)
http://purl.obolibrary.org/obo/OBI_0002135	has specified value				A relation between a value specification and a literal.
http://purl.obolibrary.org/obo/RO_0015004	has characterizing marker set				A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type.
http://purl.obolibrary.org/obo/BFO_0000055	realizes				Paraphrase of elucidation: a relation between a process and a realizable entity, where there is some material entity that is bearer of the realizable entity and participates in the process, and the realizable entity comes to be realized in the course of the process
http://purl.obolibrary.org/obo/BFO_0000067	contains process				[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
http://purl.obolibrary.org/obo/IAO_0000136	is about				A (currently) primitive relation that relates an information artifact to an entity.
http://purl.obolibrary.org/obo/OBI_0000124	is_supported_by_data				The relation between a data item and a conclusion where the conclusion is the output of a data interpreting process and the data item is used as an input to that process
http://purl.obolibrary.org/obo/OBI_0000292	has_feature_value				has_feature_value datatype property is used to describe the feature values which the feature class can contain, for example has_base can have feature values of nonNegativeInteger values.
http://purl.obolibrary.org/obo/OBI_0000294	obsolete_is_concretization_of				Is a relationship between a generically dependent continuant and a specifically dependent continuant. A generically dependent continuant may inhere in more than one entity. It does so by virtue of the fact that there is, for each entity that it inheres, a specifically dependent *concretization* of the generically dependent continuant that is specifically dependent. For instance, consider a story, which is an information artifact that inheres in some number of books. Each book bears some quality that carries the story. The relation between this quality and the generically dependent continuant is that the former is the concretization of the latter.
http://purl.obolibrary.org/obo/OBI_0000297	obsolete_is_concretized_as				Is a relationship between a specifically dependent continuant and a generically dependent continuant. A generically dependent continuant may inhere in more than one entity. It does so by virtue of the fact that there is, for each entity that it inheres, a specifically dependent *concretization* of the generically dependent continuant that is specifically dependent. For instance, consider a story, which is an information artifact that inheres in some number of books. Each book bears some quality that carries the story. The relation between this quality and the generically dependent continuant is that the former is the concretization of the latter.
http://purl.obolibrary.org/obo/OBI_0000298	obsolete_has_quality				A relation between an entity and a quality. For types: E has_quality Q iff: 
for any eEt, exists qQt such that q inheres_in e at t. 
For instances: e has_quality q at t iff q inheres_in e at t and q instance-of Quality [GOC:cjm]
http://purl.obolibrary.org/obo/OBI_0000301	obsoleted_has_specified_output_information				A relation between a participant in a process, that produces a data set . The process is the realization of a concretization of a realizable information entity (objective specification or plan specification). In general, not all data present at the end of the process are specified_data.
http://purl.obolibrary.org/obo/OBI_0000306	obsolete_has_function				Relation between an independent continuant and a function.
http://purl.obolibrary.org/obo/OBI_0000307	obsoleted_is_reagent_in				Relationship between a substance and a protocol application in which it participates, where the substance has a ReagentRole
http://purl.obolibrary.org/obo/OBI_0000309	obsoleted_utilizes_reagent				Relationship between a protocol application and a substance that has role reagent that participates in the protocol application
http://purl.obolibrary.org/obo/OBI_0000311	obsoleted_is_device_for				Relationship between a device and a protocol application in which it  participates
http://purl.obolibrary.org/obo/OBI_0000313	obsoleted_utilizes_device				Relationship between protocol application and an intrument in which it  participates
http://purl.obolibrary.org/obo/OBI_0000314	is_proxy_for				A relation between continuant instances c1 and c2 where within an experiment/ protocol application,  measurement of c1 is used to determine what a measurement of c2 would be.
http://purl.obolibrary.org/obo/OBI_0000316	obsolete_has_role				A relation between a continuant C and a role R. The reciprocal relation of role_of.
http://purl.obolibrary.org/obo/OBI_0000417	achieves_planned_objective				This relation obtains between a planned process and a objective specification when the criteria specified in the objective specification are met at the end of the planned process.
http://purl.obolibrary.org/obo/OBI_0000459	obsoleted_is_specified_information_output_of				A relation between a data set and the process in which it participates and was produced.  Inverse of outputs_specified_data relation.
http://purl.obolibrary.org/obo/OBI_0000644	obsoleted_is_specified_information_intput_of				Is the inverse relation of has_specfied_input_information
http://purl.obolibrary.org/obo/OBI_0000647	has_supplier				A relation between a material entity and an organisation or person who owned or has license to the material entity and there was a legal transfer of ownership or licensing of the material entity to the current owner.
http://purl.obolibrary.org/obo/OBI_0000833	objective_achieved_by				This relation obtains between an objective specification and a planned process when the criteria specified in the objective specification are met at the end of the planned process.
http://purl.obolibrary.org/obo/OBI_0000846	is member of organization				Relating a legal person or organization to an organization in the case where the legal person or organization has a role as member of the organization.
http://purl.obolibrary.org/obo/OBI_0001637	has disposition to bind				A relationship between two material entitites that each have disposition to form a complex with the other.
http://purl.obolibrary.org/obo/OBI_0001688	has organization member				Relating an organization to a legal person or organization.
http://purl.obolibrary.org/obo/OBI_1110119	bound_to				A relationship between two material entities that form a complex based on a selective, non-covalent interaction.
http://purl.obolibrary.org/obo/RO_0000058	is concretized as				A relationship between a generically dependent continuant and a specifically dependent continuant or process, in which the generically dependent continuant depends on some independent continuant or process in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. A generically dependent continuant may be concretized as multiple specifically dependent continuants or processes.
http://purl.obolibrary.org/obo/RO_0000059	concretizes				A relationship between a specifically dependent continuant or process and a generically dependent continuant, in which the generically dependent continuant depends on some independent continuant in virtue of the fact that the specifically dependent continuant or process also depends on that same independent continuant. Multiple specifically dependent continuants or processes can concretize the same generically dependent continuant.
http://purl.obolibrary.org/obo/RO_0009001	has substance added				"has substance added" is a relation existing between a (physical) entity and a substance in which the entity has had the substance added to it at some point in time.
http://purl.obolibrary.org/obo/RO_0007000	has driver				A relation between two entities, in which one of the entities is any natural or human-influenced factor that directly or indirectly causes a change in the other entity.
http://purl.obolibrary.org/obo/RO_0017001	device utilizes material				X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y.
http://purl.obolibrary.org/obo/RO_0003000	produces				a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.
http://purl.obolibrary.org/obo/RO_0003001	produced by				a produced_by b iff some process that occurs_in b has_output a.
http://purl.obolibrary.org/obo/RO_0015001	has exemplar data				A relation between a material entity and some data in which the data is taken as exemplifying the material entity.
http://purl.obolibrary.org/obo/RO_0002434	interacts with				A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
http://purl.obolibrary.org/obo/RO_0002573	has modifier				A relation that holds between an attribute or a qualifier and another attribute.
http://purl.obolibrary.org/obo/RO_0009003	immersed in				"immersed in" is a relation between a (physical) entity and a fluid substance in which the entity is wholely or substantially surrounded by the substance.
http://purl.obolibrary.org/obo/OBI_0003385	has assay target context				A relation between  the target entity of an assay and a material entity, where the material entity is the environment in which the target entity of an assay is measured, such as a live mouse, cell culture, test tube, etc.
http://purl.obolibrary.org/obo/RO_0002029	has increased age-specific mortality rate				Then percentage of organisms in a population that die during some specified age range (age-specific mortality rate), minus the percentage that die in during the same age range in a wild-type population.
http://purl.obolibrary.org/obo/RO_0015006	different in magnitude relative to				q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
http://purl.obolibrary.org/obo/RO_0015009	similar in magnitude relative to				q1 similar_in_magnitude_relative_to q2 if and only if magnitude(q1) =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale.
http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to				A mereological relationship or a topological relationship
http://purl.obolibrary.org/obo/RO_0002328	functionally related to				A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
http://purl.obolibrary.org/obo/RO_0002214	has prototype				x has prototype y if and only if x is an instance of C and y is a prototypical instance of C. For example, every instance of heart, both normal and abnormal is related by the has prototype relation to some instance of a "canonical" heart, which participates in blood circulation.
http://purl.obolibrary.org/obo/RO_0015011	has cross section				s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2.
http://purl.obolibrary.org/obo/RO_0015012	reciprocal of				q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e.
http://purl.obolibrary.org/obo/RO_0009006	assay measures characteristic				A relation between an assay and a characteristic, in which the assay generates a data item which is a measure of a characteristic.
http://purl.obolibrary.org/obo/RO_0009007	characteristic measured by assay				Inverse of 'assay measures characteristic'
http://purl.obolibrary.org/obo/RO_0017006	has maximum capacity				A relation that relates a container to a measurement datum that specifies the maximum capacity of the container. Capacity can refer to either weight or volume.
http://purl.obolibrary.org/obo/RO_0017008	owns				A primitive relation that holds between entities x and y in which y is at x's full disposal.
http://purl.obolibrary.org/obo/RO_0017009	is owned by				Inverse of the owns relation.
http://purl.obolibrary.org/obo/RO_0017502	collected during				A relation between a material entity and an occurrent in which the material entity is collected during the existence of the occurrent.
http://purl.obolibrary.org/obo/RO_0020104	is neuron				This property only applies to neurons
http://purl.obolibrary.org/obo/RO_0020105	is anatomical entity				This property only applies to anatomical entities.
http://purl.obolibrary.org/obo/RO_0002330	genomically related to				holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts.
http://purl.obolibrary.org/obo/OBI_0003704	is study design of				A relation between a study design and an investigation when part of the investigation is a study design execution that carries out the study design.
http://purl.obolibrary.org/obo/RO_0002321	ecologically related to				A relationship that is mediated in some way by the environment or environmental feature (ENVO:00002297)
http://purl.obolibrary.org/obo/RO_0009002	has substance removed				"has substance removed" is a relation existing between two physical entities in which the first entity has had the second entity (a substance) removed from it at some point in time.
http://purl.obolibrary.org/obo/IAO_0000235	denoted by				inverse of the relation 'denotes'
http://purl.obolibrary.org/obo/RO_0017005	contains measured amount				A relation between a container and measurement datum that specifies the actual amount of material in the container.
http://purl.obolibrary.org/obo/RO_0002134	innervates				Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input.
T innervates some R
Expands_to: T has_fasciculating_neuron_projection that synapse_in some R.
http://purl.obolibrary.org/obo/RO_0000300	obsolete in neural circuit with				OBSOLETE A relation that holds between two neurons connected directly via a synapse, or indirectly via a series of synaptically connected neurons.
http://purl.obolibrary.org/obo/RO_0000301	obsolete upstream in neural circuit with				OBSOLETE A relation that holds between a neuron that is synapsed_to another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_to the next, in which the direction is from the last to the first.
http://purl.obolibrary.org/obo/RO_0000302	obsolete downstream in neural circuit with				OBSOLETE A relation that holds between a neuron that is synapsed_by another neuron or a neuron that is connected indirectly to another by a chain of neurons, each synapsed_by the next, in which the direction is from the last to the first.
http://purl.obolibrary.org/obo/RO_0002005	innervated by				relation between an anatomical structure and a neuron projection bundle that has synaptic terminals in the structure.
http://purl.obolibrary.org/obo/RO_0002410	causally related to				relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause.
http://purl.obolibrary.org/obo/RO_0002479	has part that occurs in				p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
http://purl.obolibrary.org/obo/RO_0002609	obsolete related via dependence to				A relationship that holds between two entities, where the relationship holds based on the presence or absence of statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.
http://purl.obolibrary.org/obo/OBI_0003703	has study design				A relation between an investigation and a study design in which part of the investigation is a study design execution that carries out the study design.
http://purl.obolibrary.org/obo/RO_0002201	phenotype of				inverse of has phenotype
http://purl.obolibrary.org/obo/RO_0018003	myristoylated by				inverse of myristoylates
http://purl.obolibrary.org/obo/OBI_0002815	has representation				'has representation' is a data property that attaches between an information content entity and a value that contains linguistically or computationally coded text.
http://purl.obolibrary.org/obo/RO_0002011	regulates transport of				A relationship that holds between a  process that regulates a transport process and the entity transported by that process.
http://purl.obolibrary.org/obo/RO_0002337	related via localization to				A relationship that holds via some process of localization
http://purl.obolibrary.org/obo/RO_0002514	sequentially related to				A relation that holds between two entities that have the property of being sequences or having sequences. 
http://purl.obolibrary.org/obo/RO_0002610	correlated with				A relationship that holds between two entities, where the entities exhibit a statistical dependence relationship. The entities may be statistical variables, or they may be other kinds of entities such as diseases, chemical entities or processes.
http://purl.obolibrary.org/obo/RO_0002615	has model				Inverse of is-model-of
http://purl.obolibrary.org/obo/RO_0010001	generically depends on				A generically dependent continuant *b* generically depends on an independent continuant *c* at time *t* means: there inheres in *c* a specifically deendent continuant which concretizes *b* at *t*.
http://purl.obolibrary.org/obo/RO_0010002	is carrier of				*b* is carrier of *c* at time *t* if and only if *c* *g-depends on* *b* at *t*
http://purl.obolibrary.org/obo/RO_0040035	disease relationship				This relation groups  relations between diseases and any other kind of entity.
http://purl.obolibrary.org/obo/ENVO_01003004	derives from part of				A relation between two distinct material entities, the new entity and the old entity, in which the new entity begins to exist through the separation or transformation of a part of the old entity, and the new entity inherits a significant portion of the matter belonging to that part of the old entity.
http://purl.obolibrary.org/obo/BFO_0000054	realized in			realized_in	
http://purl.obolibrary.org/obo/RO_0001018	obsolete contained in			contained_in	
http://purl.obolibrary.org/obo/RO_0002111	releases neurotransmitter			has neurotransmitter	
http://purl.obolibrary.org/obo/BFO_0000060	obsolete preceded by				
http://purl.obolibrary.org/obo/IAO_0000004	has measurement value				
http://purl.obolibrary.org/obo/OBI_0000365	obsolete_results_from				
http://purl.obolibrary.org/obo/OBI_1110112	obsolete_is_described_by				
http://purl.obolibrary.org/obo/RO_0004096	DEPRECATED inheres in				
http://purl.obolibrary.org/obo/RO_0004097	DEPRECATED bearer of				
http://purl.obolibrary.org/obo/RO_0016001	has phenotype or disease				
http://purl.obolibrary.org/obo/RO_0002408	obsolete directly inhibits				
http://purl.obolibrary.org/obo/RO_0002424	differs in				
http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)				
http://purl.obolibrary.org/obo/RO_0002487	relation between physical entity and a process or stage				
http://purl.obolibrary.org/obo/RO_0002401	obsolete has indirect input				
http://purl.obolibrary.org/obo/RO_0002222	temporally related to				
http://purl.obolibrary.org/obo/RO_0018030	chemical relationship				
http://purl.obolibrary.org/obo/RO_0002502	depends on				
http://purl.obolibrary.org/obo/RO_0015010	has relative magnitude				
http://purl.obolibrary.org/obo/RO_0015002	exemplar data of				
http://purl.obolibrary.org/obo/RO_0001019	obsolete contains				
http://purl.obolibrary.org/obo/RO_0002001	aligned with				
http://purl.obolibrary.org/obo/RO_0002403	obsolete has indirect output				
http://purl.obolibrary.org/obo/RO_0002406	obsolete directly activates				
http://purl.obolibrary.org/obo/RO_0002616	related via evidence or inference to