Term IRI Term label Parent term IRI Parent term label Alternative term Definition http://purl.obolibrary.org/obo/GO_0098691 dopaminergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses dopamine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0099140 presynaptic actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0099187 presynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the presynaptic actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0099143 presynaptic actin cytoskeleton http://purl.obolibrary.org/obo/GO_0015629 actin cytoskeleton The actin cytoskeleton that is part of a presynapse. http://purl.obolibrary.org/obo/GO_0099145 regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of exocytic fusion of neurotransmitter receptor containing vesicles into the postsynaptic membrane. http://purl.obolibrary.org/obo/UBERON_0036244 secretion of serous membrane http://purl.obolibrary.org/obo/UBERON_0007779 transudate A transudate found in the serous sac. http://purl.obolibrary.org/obo/CHEBI_138103 inorganic acid http://purl.obolibrary.org/obo/CHEBI_39141 Bronsted acid A Brønsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water. http://purl.obolibrary.org/obo/GO_0061951 establishment of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane The directed movement of a protein to a specific location in a plasma membrane. http://purl.obolibrary.org/obo/GO_0140272 exogenous protein binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a protein or protein complex from a different species, for example a pathogen molecule binding to a host protein. http://purl.obolibrary.org/obo/UBERON_0036289 anterior wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0036286 wall of right ventricle Region of wall of right ventricle which is continuous with the lateral and septal walls of right ventricle. http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human DRD1 to DRD5 genes, 1:1 orthologs thereof, or pro-orthologs thereof. http://purl.obolibrary.org/obo/GO_0120178 steroid hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0006694 steroid biosynthetic process The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0062125 regulation of mitochondrial gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of mitochondrial gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/PHIPO_0000970 autophagosomes present in decreased numbers http://purl.obolibrary.org/obo/PHIPO_0000973 autophagosome phenotype A single organism phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer autophagosomes than normal (GO:0005776). http://purl.obolibrary.org/obo/PHIPO_0000971 abolished formation of autophagosomes http://purl.obolibrary.org/obo/PHIPO_0000973 autophagosome phenotype A single organism phenotype observed in the vegetative growth phase of the life cycle in which the ability of the organism to form autophagosomes is abolished (they were present and are now absent) (GO:0005776). http://purl.obolibrary.org/obo/PHIPO_0000972 abolished protein localization to autophagosome http://purl.obolibrary.org/obo/PHIPO_0000245 abolished protein localization A single organism phenotype in which a protein does not localize to, and is therefore absent from the autophagosome (GO:0005776). http://purl.obolibrary.org/obo/PHIPO_0000973 autophagosome phenotype http://purl.obolibrary.org/obo/PHIPO_0000415 abnormal subcellular component A single organism phenotype that affects a double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy (GO:0005776). http://purl.obolibrary.org/obo/PHIPO_0000974 decreased unicellular population growth http://purl.obolibrary.org/obo/PHIPO_0000414 abnormal unicellular population growth A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is lesser than normal. http://purl.obolibrary.org/obo/PHIPO_0000975 increased unicellular population growth http://purl.obolibrary.org/obo/PHIPO_0000414 abnormal unicellular population growth A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is greater than normal. http://purl.obolibrary.org/obo/PHIPO_0000976 decreased lipid droplet degradation http://purl.obolibrary.org/obo/PHIPO_0000493 primary metabolic process phenotype A single organism metabolic process phenotype in which the occurrence of lipid droplet degradation (lipolysis) is decreased (GO:0016042 and GO:0005811). http://purl.obolibrary.org/obo/PHIPO_0000977 sensitive to sodium dodecyl sulfate http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A phenotype in which a population of a single-species shows increased sensitivity to sodium dodecyl sulfate (SDS), manifested as an affect on the extent of population growth. (CHEBI:8984). http://purl.obolibrary.org/obo/PHIPO_0000978 sensitive to sodium chloride http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A phenotype in which a population of a single-species shows increased sensitivity to sodium chloride, manifested as an affect on the extent of population growth. (CHEBI:26710). http://purl.obolibrary.org/obo/PHIPO_0000979 sensitive to dithiothreitol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A phenotype in which a population of a single-species shows increased sensitivity to 1,4-dithiothreitol (DTT), manifested as an affect on the extent of population growth. (CHEBI:18320). http://purl.obolibrary.org/obo/PHIPO_0000980 normal sexual spore morphology http://purl.obolibrary.org/obo/PHIPO_0000046 normal sexual reproduction A reproductive phenotype where the morphology of the sexual spore is normal (FAO:0000017). The product of meiosis. http://purl.obolibrary.org/obo/PHIPO_0000981 abnormal meiosis http://purl.obolibrary.org/obo/PHIPO_0000400 abnormal cellular component organization A reproductive process phenotype in which meiosis is abnormal. Meiosis refers specifically to the nuclear division phases of a meiotic cell cycle. (GO:0140013). http://purl.obolibrary.org/obo/PHIPO_0000982 normal meiosis http://purl.obolibrary.org/obo/PHIPO_0000984 normal meiotic cell cycle A reproductive process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type). (GO:0140013). http://purl.obolibrary.org/obo/PHIPO_0000983 abnormal meiotic cell cycle http://purl.obolibrary.org/obo/PHIPO_0000048 abnormal sexual reproduction A reproductive process phenotype in which a cell does not proceed normally through a meiotic cell cycle (GO:0051321). http://purl.obolibrary.org/obo/PHIPO_0000984 normal meiotic cell cycle http://purl.obolibrary.org/obo/PHIPO_0000046 normal sexual reproduction A reproductive process phenotype in which a cell proceeds normally through a meiotic cell cycle (GO:0051321). http://purl.obolibrary.org/obo/GO_0150119 negative regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/GO_0150146 cell junction disassembly http://purl.obolibrary.org/obo/GO_0034330 cell junction organization The disaggregation of a cell junction into its constituent components. http://purl.obolibrary.org/obo/CHEBI_145556 macrodiolide http://purl.obolibrary.org/obo/CHEBI_145555 macropolylide A macropolylide which contains two ester linkages in one macrocyclic ring. http://purl.obolibrary.org/obo/GO_0120229 protein localization to motile cilium http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a motile cilium. http://purl.obolibrary.org/obo/GO_0120254 olefinic compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). http://purl.obolibrary.org/obo/GO_0120255 olefinic compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of an olefinic compound, any compound which contains a carbon-carbon double bond (aka C=C). http://purl.obolibrary.org/obo/CL_0009097 embryonic skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle fiber found in an embryo. In mammalian embryos, skeletal muscle expresses myosin heavy chain-embryonic (MyHC-emb, encoded by the MYH3 gene), which regulates skeletal muscle development. http://purl.obolibrary.org/obo/UBERON_8480001 capillary of brain http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel A capillary that is part of the brain. http://purl.obolibrary.org/obo/UBERON_8480002 thoracic aorta smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004178 aorta smooth muscle tissue A portion of smooth muscle tissue that is part of the thoracic aorta. http://purl.obolibrary.org/obo/GO_0160043 catecholamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of catecholamine by a cell in which the catecholamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/CL_4023029 indirect pathway medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A GABAergic medium spiny neuron located in the striatum that gives rise to the indirect basal ganglia pathway. It projects to the GPe, where its axon typically ramifies in two regions but does not extend beyond this nucleus (Gerfen et al., 2022). It selectively expresses the D2 dopamine receptor (DRD2), which couples to inhibitory G-proteins (Gi/o) to decrease cAMP and suppress PKA-mediated signaling (Gerfen et al., 2022). Morphologically, this cell displays fewer and shorter dendrites than the MSN-D1 and receives fewer glutamatergic inputs, yet it exhibits significantly higher intrinsic excitability (Gertler et al., 2022). Functionally, activation of this cell suppresses competing or alternative motor actions by inhibiting GPe neurons, leading through STN and other GPe circuits to increased GPi/SNr output and stronger inhibition of thalamic and brainstem targets (Mink, 1996; Tecuapetla et al., 2016). http://purl.obolibrary.org/obo/PHIPO_0001388 resistance to pyrisoxazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to pyrisoxazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001389 sensitive to pyrisoxazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrisoxazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001390 normal growth on pyrisoxazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrisoxazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001391 resistance to metconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to metconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001392 sensitive to metconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to metconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001393 normal growth on metconazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to metconazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001394 resistance to trifloxystrobin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to trifloxystrobin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001395 sensitive to trifloxystrobin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to trifloxystrobin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001396 normal growth on trifloxystrobin http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to trifloxystrobin (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001397 sensitive to cell wall stress http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress A growth phenotype which describes the sensitivity of individuals or populations after exposure to a cell wall stress. Typically, individuals or populations are deemed sensitive to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). http://purl.obolibrary.org/obo/PHIPO_0001398 sensitive to oxidative stress http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress A growth phenotype which describes the sensitivity of individuals or populations after exposure to an oxidative stress. Typically, individuals or populations are deemed sensitive to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). http://purl.obolibrary.org/obo/PHIPO_0001399 resistance to flusilazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to flusilazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001400 sensitive to flusilazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to flusilazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001401 normal growth on flusilazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to flusilazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001402 resistance to mandipropamid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to mandipropamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001403 sensitive to mandipropamid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to mandipropamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001404 normal growth on mandipropamid http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to mandipropamid (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001405 resistance to dimethomorph http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to dimethomorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001406 sensitive to dimethomorph http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to dimethomorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001407 normal growth on dimethomorph http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to dimethomorph (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001408 resistance to iprovalicarb http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to iprovalicarb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001409 sensitive to iprovalicarb http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to iprovalicarb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001410 normal growth on iprovalicarb http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to iprovalicarb (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PR_000064867 protein-containing molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity that minimally consists of a protein. http://purl.obolibrary.org/obo/PHIPO_0001411 resistance to dalfopristin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to dalfopristin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001412 sensitive to dalfopristin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to dalfopristin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001413 normal growth on dalfopristin http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to dalfopristin (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001414 resistance to thifluzamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to thifluzamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001415 sensitive to thifluzamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to thifluzamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001416 normal growth on thifluzamide http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to thifluzamide (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001417 resistance to penflufen http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to penflufen. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001418 sensitive to penflufen http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to penflufen. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001419 normal growth on penflufen http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to penflufen (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001420 resistance to flutolanil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to flutolanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001421 sensitive to flutolanil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to flutolanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001422 normal growth on flutolanil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to flutolanil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001423 resistance to imazalil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to imazalil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001424 sensitive to imazalil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to imazalil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001425 normal growth on imazalil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to imazalil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001426 normal growth on fludioxonil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to fludioxonil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001427 abnormal hyphal branching http://purl.obolibrary.org/obo/PHIPO_0001205 abnormal filament morphology A single species cell morphology phenotype in which fungal hyphae branching is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001428 normal growth on brefeldin A http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to brefeldin A (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001429 normal growth on fluconazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to fluconazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001430 resistance to ipconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ipconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001431 sensitive to ipconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ipconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001432 normal growth on ipconazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to ipconazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001433 resistance to cyprodinil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cyprodinil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001434 sensitive to cyprodinil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyprodinil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001435 normal growth on cyprodinil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to cyprodinil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001436 normal growth on caspofungin http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to caspofungin (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001437 normal growth on terbinafine http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to terbinafine (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001438 normal growth on bifonazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to bifonazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/CHEBI_231550 azithromycin(2+) http://purl.obolibrary.org/obo/CHEBI_137982 tertiary ammonium ion A tertiary ammonium ion resulting from the protonation of the two amino groups of azithromycin; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_231553 levofloxacin(1-) http://purl.obolibrary.org/obo/CHEBI_35902 oxo monocarboxylic acid anion An oxo monocarboxylic acid anion that is the conjugate base of levofloxacin resulting from the deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/PATO_0103000 quantitative http://purl.obolibrary.org/obo/PATO_0000001 quality A quality of an entity that can be represented numerically, including anything that can be counted, measured, or given a numerical value. http://purl.obolibrary.org/obo/UBERON_8600123 lower airway ganglion http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion A parasympathetic ganglion that is located within the airway walls of the lower respiratory tract. This ganglion is responsible for controlling the constriction of the airway by stimulating smooth muscle contraction in the lower respiratory tract to regulate airflow. http://purl.obolibrary.org/obo/CL_4307032 Astro-NT NN_1 Kcnk10 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Agt (Mmus), Prss35 (Mmus), C4b (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Kcnk10, C4b. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5212 Astro-NT NN_1. http://purl.obolibrary.org/obo/CHEBI_132142 1,4-naphthoquinones http://purl.obolibrary.org/obo/CHEBI_25481 naphthoquinone A naphthoquinone in which the oxo groups of the quinone moiety are at positions 1 and 4 of the parent naphthalene ring. http://purl.obolibrary.org/obo/CHEBI_15841 polypeptide http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A peptide containing ten or more amino acid residues. http://purl.obolibrary.org/obo/CHEBI_22715 benzimidazoles http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound An organic heterocyclic compound containing a benzene ring fused to an imidazole ring. http://purl.obolibrary.org/obo/CHEBI_23066 cephalosporin http://purl.obolibrary.org/obo/CHEBI_38311 cephem A class of β-lactam antibiotics differing from the penicillins in having a 6-membered, rather than a 5-membered, side ring. Although cephalosporins are among the most commonly used antibiotics in the treatment of routine infections, and their use is increasing over time, they can cause a range of hypersensitivity reactions, from mild, delayed-onset cutaneous reactions to life-threatening anaphylaxis in patients with immunoglobulin E (IgE)-mediated allergy. http://purl.obolibrary.org/obo/CHEBI_23763 pyrroline http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound Any organic heteromonocyclic compound with a structure based on a dihydropyrrole. http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid Any terpenoid derived from a diterpene. The term includes compounds in which the C20 skeleton of the parent diterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). http://purl.obolibrary.org/obo/CHEBI_24129 furans http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Compounds containing at least one furan ring. http://purl.obolibrary.org/obo/CHEBI_24628 imidazolidine-2,4-dione http://purl.obolibrary.org/obo/CHEBI_55370 imidazolidinone An imidazolidinone with oxo groups at position 2 and 4. http://purl.obolibrary.org/obo/CHEBI_24654 hydroxy fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid carrying one or more hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_25000 lactone http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. http://purl.obolibrary.org/obo/CHEBI_25512 neurotransmitter http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. http://purl.obolibrary.org/obo/CHEBI_25698 ether http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound An organooxygen compound with formula ROR, where R is not hydrogen. http://purl.obolibrary.org/obo/CHEBI_26191 polyol http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound A compound that contains two or more hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_26455 pyrroles http://purl.obolibrary.org/obo/CHEBI_68452 azole An azole that includes only one N atom and no other heteroatom as a part of the aromatic skeleton. http://purl.obolibrary.org/obo/CHEBI_26513 quinolines http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring. http://purl.obolibrary.org/obo/CHEBI_26776 stilbenoid http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound Any olefinic compound characterised by a 1,2-diphenylethylene backbone. http://purl.obolibrary.org/obo/CHEBI_27311 volatile oil component http://purl.obolibrary.org/obo/CHEBI_76924 plant metabolite Any plant metabolite that is found naturally as a component of a volatile oil. http://purl.obolibrary.org/obo/CHEBI_27933 beta-lactam antibiotic http://purl.obolibrary.org/obo/CHEBI_25558 organonitrogen heterocyclic antibiotic An organonitrogen heterocyclic antibiotic that contains a β-lactam ring. http://purl.obolibrary.org/obo/CHEBI_29256 thiol http://purl.obolibrary.org/obo/CHEBI_33261 organosulfur compound An organosulfur compound in which a thiol group, ‒SH, is attached to a carbon atom of any aliphatic or aromatic moiety. http://purl.obolibrary.org/obo/CHEBI_32952 amine http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/CHEBI_33261 organosulfur compound http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity An organosulfur compound is a compound containing at least one carbon-sulfur bond. http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity An organic compound having at least one hydroxy group attached to a carbon atom. http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene. http://purl.obolibrary.org/obo/CHEBI_35356 dicarboximide http://purl.obolibrary.org/obo/CHEBI_24782 imide An imide in which the two acyl substituents on nitrogen are carboacyl groups. http://purl.obolibrary.org/obo/CHEBI_35444 antinematodal drug http://purl.obolibrary.org/obo/CHEBI_35443 anthelminthic drug A substance used in the treatment or control of nematode infestations. http://purl.obolibrary.org/obo/CHEBI_35627 beta-lactam http://purl.obolibrary.org/obo/CHEBI_24995 lactam A lactam in which the amide bond is contained within a four-membered ring, which includes the amide nitrogen and the carbonyl carbon. http://purl.obolibrary.org/obo/CHEBI_35689 tetrazoles http://purl.obolibrary.org/obo/CHEBI_68452 azole An azole in which the five-membered heterocyclic aromatic skeleton contains four N atoms and one C atom. http://purl.obolibrary.org/obo/CHEBI_35715 nitro compound http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity A compound having a nitro group, ‒NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied). http://purl.obolibrary.org/obo/CHEBI_35716 C-nitro compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule A nitro compound having the nitro group (‒NO2) attached to a carbon atom. http://purl.obolibrary.org/obo/CHEBI_36233 disaccharide http://purl.obolibrary.org/obo/CHEBI_50699 oligosaccharide A compound in which two monosaccharides are joined by a glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_36785 carbobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound A bicyclic compound in which all the ring atoms are carbon. http://purl.obolibrary.org/obo/CHEBI_38032 carbotricyclic compound http://purl.obolibrary.org/obo/CHEBI_51959 organic tricyclic compound A carbopolyclic compound comprising of three carbocyclic rings. http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms. http://purl.obolibrary.org/obo/CHEBI_38260 pyrrolidines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound Any of a class of heterocyclic amines having a saturated five-membered ring. http://purl.obolibrary.org/obo/CHEBI_39201 phenazines http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound Any organonitrogen heterocyclic compound based on a phenazine skeleton and derivatives. http://purl.obolibrary.org/obo/CHEBI_50695 monobactam http://purl.obolibrary.org/obo/CHEBI_27933 beta-lactam antibiotic Monocyclic, bacterially produced or semisynthetic beta-lactam antibiotic. It lacks the double ring construction of the traditional beta-lactam antibiotics and can be easily synthesized. http://purl.obolibrary.org/obo/CHEBI_50902 genotoxin http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. http://purl.obolibrary.org/obo/CHEBI_50904 allergen http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. http://purl.obolibrary.org/obo/CHEBI_51276 thioureas http://purl.obolibrary.org/obo/CHEBI_50492 thiocarbonyl compound Compounds of general formula RR'NC(=S)NR''R'''. http://purl.obolibrary.org/obo/CHEBI_51867 methyl ketone http://purl.obolibrary.org/obo/CHEBI_17087 ketone A ketone of formula RC(=O)CH3 (R ≠ H). http://purl.obolibrary.org/obo/CHEBI_5686 heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclic compound having as ring members atoms of at least two different elements. http://purl.obolibrary.org/obo/CHEBI_59163 biomarker http://purl.obolibrary.org/obo/CHEBI_47867 indicator A substance used as an indicator of a biological state. http://purl.obolibrary.org/obo/CHEBI_64915 antiplasmodial drug http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria. http://purl.obolibrary.org/obo/CHEBI_67079 anti-inflammatory agent http://purl.obolibrary.org/obo/CHEBI_33232 application Any compound that has anti-inflammatory effects. http://purl.obolibrary.org/obo/CHEBI_72544 flavonoids http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them. http://purl.obolibrary.org/obo/CHEBI_76967 human xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. http://purl.obolibrary.org/obo/CHEBI_83056 Daphnia magna metabolite http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite A Daphnia metabolite produced by the species Daphnia magna. http://purl.obolibrary.org/obo/CHEBI_26069 phosphonic acids http://purl.obolibrary.org/obo/CHEBI_36360 phosphorus oxoacids and derivatives HP(=O)(OH)2 (phosphonic acid) and its P-substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_38716 carboxylic acid dianion A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_32876 tertiary amine http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/CHEBI_33231 antitubercular agent http://purl.obolibrary.org/obo/CHEBI_64912 antimycobacterial drug A substance that kills or slows the growth of Mycobacterium tuberculosis and is used in the treatment of tuberculosis. http://purl.obolibrary.org/obo/CHEBI_37699 protein kinase inhibitor http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases. http://purl.obolibrary.org/obo/CHEBI_44976 phosphonic acid http://purl.obolibrary.org/obo/CHEBI_33457 phosphorus oxoacid A phosphorus oxoacid that consists of a single pentavalent phosphorus covalently bound via single bonds to a single hydrogen and two hydroxy groups and via a double bond to an oxygen. The parent of the class of phosphonic acids. http://purl.obolibrary.org/obo/CHEBI_60251 guanidinium ion http://purl.obolibrary.org/obo/CHEBI_35286 iminium ion R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives. http://purl.obolibrary.org/obo/CHEBI_64049 food acidity regulator http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents. http://purl.obolibrary.org/obo/CHEBI_74783 astringent http://purl.obolibrary.org/obo/CHEBI_23888 drug A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions. http://purl.obolibrary.org/obo/CHEBI_131605 dicarboxylic acid monoester(1-) http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acid anion resulting from the deprotonation of the carboxy group of a dicarboxylic acid monoester. http://purl.obolibrary.org/obo/CHEBI_131609 pneumocandin B0 http://purl.obolibrary.org/obo/CHEBI_57248 echinocandin An echinocandin initially isolated as a very minor bioactive fermentation product of Glarea lozoyensis (originally known as Zalerion arboricola). Subsequent random mutagenesis work and optimisation of the fermentation medium permitted the industrial production of pneumocandin B0, which is used as the starting point for the synthesis of the antifungal drug caspofungin. http://purl.obolibrary.org/obo/CHEBI_131871 hydroxy polyunsaturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_59835 hydroxy fatty acid anion Any polyunsaturated fatty acid anion carrying one or more hydroxy substituents. http://purl.obolibrary.org/obo/CHEBI_131927 dicarboxylic acids and O-substituted derivatives http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens. http://purl.obolibrary.org/obo/CHEBI_132130 hydroxyquinone http://purl.obolibrary.org/obo/CHEBI_36141 quinone Any quinone in which one or more of the carbons making up the quinone moiety is substituted by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_132155 hydroxynaphthoquinone http://purl.obolibrary.org/obo/CHEBI_25481 naphthoquinone Any naphthoquinone in which the naphthaoquinone moiety is substituted by at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_132157 hydroxy-1,4-naphthoquinone http://purl.obolibrary.org/obo/CHEBI_132155 hydroxynaphthoquinone Any member of the class of 1,4-naphthoquinones in which the naphthoquinone moiety is substituted by at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_132717 bleaching agent http://purl.obolibrary.org/obo/CHEBI_33893 reagent A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties. http://purl.obolibrary.org/obo/CHEBI_133135 chromenochromene http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound Any organic heteroolycyclic compound whose skeleton two ortho-fused chromene rings, and their derivatives. http://purl.obolibrary.org/obo/CHEBI_13643 glycol http://purl.obolibrary.org/obo/CHEBI_23824 diol A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. http://purl.obolibrary.org/obo/CHEBI_15366 acetic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A simple monocarboxylic acid containing two carbons. http://purl.obolibrary.org/obo/CHEBI_15940 nicotinic acid http://purl.obolibrary.org/obo/CHEBI_26420 pyridinemonocarboxylic acid A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. http://purl.obolibrary.org/obo/CHEBI_16040 cytosine http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4. http://purl.obolibrary.org/obo/CHEBI_17203 L-proline http://purl.obolibrary.org/obo/CHEBI_26271 proline Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group α to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. http://purl.obolibrary.org/obo/CHEBI_17296 aniline http://purl.obolibrary.org/obo/CHEBI_50471 primary arylamine A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens. http://purl.obolibrary.org/obo/CHEBI_17334 penicillin http://purl.obolibrary.org/obo/CHEBI_25865 penicillanic acids Any member of the group of substituted penams containing two methyl substituents at position 2, a carboxylate substituent at position 3 and a carboxamido group at position 6. http://purl.obolibrary.org/obo/CHEBI_17499 hydrogen donor http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity that can undergo oxidation by the loss of hydrogen atom(s). http://purl.obolibrary.org/obo/CHEBI_17996 chloride http://purl.obolibrary.org/obo/CHEBI_33432 monoatomic chlorine A halide anion formed when chlorine picks up an electron to form an an anion. http://purl.obolibrary.org/obo/CHEBI_18059 lipid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. http://purl.obolibrary.org/obo/CHEBI_18208 benzylpenicillin http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group. http://purl.obolibrary.org/obo/CHEBI_18310 alkane http://purl.obolibrary.org/obo/CHEBI_33653 aliphatic compound An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms. http://purl.obolibrary.org/obo/CHEBI_18375 nucleoside 3',5'-cyclic phosphate http://purl.obolibrary.org/obo/CHEBI_23447 cyclic nucleotide A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate. http://purl.obolibrary.org/obo/CHEBI_22562 anilines http://purl.obolibrary.org/obo/CHEBI_33860 aromatic amine Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_22917 phytogenic insecticide http://purl.obolibrary.org/obo/CHEBI_24852 insecticide An insecticide compound naturally occurring in plants. http://purl.obolibrary.org/obo/CHEBI_23357 cofactor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). http://purl.obolibrary.org/obo/CHEBI_23666 diamine http://purl.obolibrary.org/obo/CHEBI_88061 polyamine Any polyamine that contains two amino groups. http://purl.obolibrary.org/obo/CHEBI_23824 diol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols. http://purl.obolibrary.org/obo/CHEBI_24079 formamides http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide Amides with the general formula R1R2NCHO (R1 and R2 can be H). http://purl.obolibrary.org/obo/CHEBI_24533 heterodetic cyclic peptide http://purl.obolibrary.org/obo/CHEBI_23449 cyclic peptide A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond. http://purl.obolibrary.org/obo/CHEBI_24613 homodetic cyclic peptide http://purl.obolibrary.org/obo/CHEBI_23449 cyclic peptide A homodetic cyclic peptide is a cyclic peptide in which the ring consists solely of amino-acid residues in peptide linkages. http://purl.obolibrary.org/obo/CHEBI_24675 hydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_22718 benzoates Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_24833 oxoacid http://purl.obolibrary.org/obo/CHEBI_24651 hydroxides A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/CHEBI_24852 insecticide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. http://purl.obolibrary.org/obo/CHEBI_25367 molecule http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity Any polyatomic entity that is an electrically neutral entity consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_25491 nematicide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance used to destroy pests of the phylum Nematoda (roundworms). http://purl.obolibrary.org/obo/CHEBI_25696 organic anion http://purl.obolibrary.org/obo/CHEBI_25699 organic ion Any organic ion with a net negative charge. http://purl.obolibrary.org/obo/CHEBI_2571 aliphatic alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol An alcohol derived from an aliphatic compound. http://purl.obolibrary.org/obo/CHEBI_2580 unsaturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety. http://purl.obolibrary.org/obo/CHEBI_26155 plant growth regulator http://purl.obolibrary.org/obo/CHEBI_39317 growth regulator A chemical, natural or artificial, that can affect the rate of growth of a plant. http://purl.obolibrary.org/obo/CHEBI_26218 potassium salt http://purl.obolibrary.org/obo/CHEBI_35479 alkali metal salt Any alkali metal salt having potassium(1+) as the cation. http://purl.obolibrary.org/obo/CHEBI_26432 pyrimidine nucleobase http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines A nucleobase whose skeleton is derived from pyrimidine. http://purl.obolibrary.org/obo/CHEBI_26607 saturated fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess. http://purl.obolibrary.org/obo/CHEBI_27026 toxin http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Poisonous substance produced by a biological organism such as a microbe, animal or plant. http://purl.obolibrary.org/obo/CHEBI_27283 very long-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid A fatty acid which has a chain length greater than C22. Very long-chain fatty acids which have a chain length greater than C27 are also known as ultra-long-chain fatty acids. http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion http://purl.obolibrary.org/obo/CHEBI_51151 dipolar compound A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer). http://purl.obolibrary.org/obo/CHEBI_27780 detergent http://purl.obolibrary.org/obo/CHEBI_33232 application A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions. http://purl.obolibrary.org/obo/CHEBI_28306 semicarbazide http://purl.obolibrary.org/obo/CHEBI_47857 ureas A monocarboxylic acid amide that is urea where one of the amino groups has been replaced with hydrazine. http://purl.obolibrary.org/obo/CHEBI_28817 dodecane http://purl.obolibrary.org/obo/CHEBI_18310 alkane A straight-chain alkane with 12 carbon atoms. It has been isolated from the essential oils of various plants including Zingiber officinale (ginger). http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated. http://purl.obolibrary.org/obo/CHEBI_30089 acetate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. http://purl.obolibrary.org/obo/CHEBI_31577 ethylenediamine derivative http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound Any organic amino compound that is a derivative of ethylenediamine. http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_24433 group Any substituent group or skeleton containing carbon. http://purl.obolibrary.org/obo/CHEBI_33554 organosulfonate oxoanion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid. http://purl.obolibrary.org/obo/CHEBI_33708 amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33247 organic group When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue. http://purl.obolibrary.org/obo/CHEBI_33856 aromatic amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid An amino acid whose structure includes an aromatic ring. http://purl.obolibrary.org/obo/CHEBI_33893 reagent http://purl.obolibrary.org/obo/CHEBI_33232 application A substance used in a chemical reaction to detect, measure, examine, or produce other substances. http://purl.obolibrary.org/obo/CHEBI_34043 1,2-phenylenediamine http://purl.obolibrary.org/obo/CHEBI_51402 phenylenediamine A phenylenediamine in which the two amino groups are ortho to each other. http://purl.obolibrary.org/obo/CHEBI_35195 surfactant http://purl.obolibrary.org/obo/CHEBI_63046 emulsifier A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces. http://purl.obolibrary.org/obo/CHEBI_35222 inhibitor http://purl.obolibrary.org/obo/CHEBI_24432 biological role A substance that diminishes the rate of a chemical reaction. http://purl.obolibrary.org/obo/CHEBI_35223 catalyst http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction. http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group. http://purl.obolibrary.org/obo/CHEBI_35286 iminium ion http://purl.obolibrary.org/obo/CHEBI_25697 organic cation Cations of structure R2C=N+R2. http://purl.obolibrary.org/obo/CHEBI_35294 carbopolycyclic compound http://purl.obolibrary.org/obo/CHEBI_35295 homopolycyclic compound A polyclic compound in which all of the ring members are carbon atoms. http://purl.obolibrary.org/obo/CHEBI_35362 hydrazide http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity Compounds derived from oxoacids RkE(=O)l(OH)m (l ≠ 0) by replacing ‒OH by ‒NRNR2 (R groups are commonly H). (IUPAC). http://purl.obolibrary.org/obo/CHEBI_35363 carbohydrazide http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A hydrazide consisting of hydrazine carrying one or more carboacyl groups. http://purl.obolibrary.org/obo/CHEBI_35497 androgen antagonist http://purl.obolibrary.org/obo/CHEBI_49020 hormone antagonist A compound which inhibits or antagonises the biosynthesis or actions of androgens. http://purl.obolibrary.org/obo/CHEBI_35526 hypoglycemic agent http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug which lowers the blood glucose level. http://purl.obolibrary.org/obo/CHEBI_35705 immunosuppressive agent http://purl.obolibrary.org/obo/CHEBI_50846 immunomodulator An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. http://purl.obolibrary.org/obo/CHEBI_35850 sulfone http://purl.obolibrary.org/obo/CHEBI_33261 organosulfur compound An organosulfur compound having the structure RS(=O)2R (R ≠ H). http://purl.obolibrary.org/obo/CHEBI_35856 lipoxygenase inhibitor http://purl.obolibrary.org/obo/CHEBI_76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. http://purl.obolibrary.org/obo/CHEBI_35868 hydroxy monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_24669 hydroxy carboxylic acid Any monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_35915 sterol ester http://purl.obolibrary.org/obo/CHEBI_47880 steroid ester A steroid ester obtained by formal condensation of the carboxy group of any carboxylic acid with the 3-hydroxy group of a sterol. http://purl.obolibrary.org/obo/CHEBI_35973 3-oxo monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35902 oxo monocarboxylic acid anion An oxo monocarboxylic acid anion having the oxo group located at the 3-position (R = H or organyl group). http://purl.obolibrary.org/obo/CHEBI_36141 quinone http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of ‒CH= groups into ‒C(=O)‒ groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included). http://purl.obolibrary.org/obo/CHEBI_36244 dicarboxylic acid monoester http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid A monoester of a dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_36335 trypanocidal drug http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. http://purl.obolibrary.org/obo/CHEBI_36587 organic oxo compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element. http://purl.obolibrary.org/obo/CHEBI_36700 phosphocholines http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester Any compound having phosphocholine as part of its structure. http://purl.obolibrary.org/obo/CHEBI_36816 oxime O-ether http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound O-organyl oximes R2C=NOR' (R' ≠ H). http://purl.obolibrary.org/obo/CHEBI_36835 3alpha-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol A 3-hydroxy steroid in which the 3-hydroxy substituent is in the α-position. http://purl.obolibrary.org/obo/CHEBI_36976 nucleotide http://purl.obolibrary.org/obo/CHEBI_25608 nucleoside phosphate A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid. http://purl.obolibrary.org/obo/CHEBI_37407 cyclic ether http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any ether in which the oxygen atom forms part of a ring. http://purl.obolibrary.org/obo/CHEBI_38131 lactol http://purl.obolibrary.org/obo/CHEBI_5653 hemiacetal Cyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues. http://purl.obolibrary.org/obo/CHEBI_38161 chelator http://purl.obolibrary.org/obo/CHEBI_52214 ligand A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. http://purl.obolibrary.org/obo/CHEBI_38231 phytotoxin http://purl.obolibrary.org/obo/CHEBI_76924 plant metabolite Any toxin produced by a plant. http://purl.obolibrary.org/obo/CHEBI_38623 EC 1.4.3.4 (monoamine oxidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76861 EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor An EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor that interferes with the action of monoamine oxidase (EC 1.4.3.4). http://purl.obolibrary.org/obo/CHEBI_46662 mineral http://purl.obolibrary.org/obo/CHEBI_59999 chemical substance In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals'). http://purl.obolibrary.org/obo/CHEBI_46774 polyether http://purl.obolibrary.org/obo/CHEBI_25698 ether Any ether that contains more than one ether linkage. http://purl.obolibrary.org/obo/CHEBI_46786 diether http://purl.obolibrary.org/obo/CHEBI_46774 polyether A polyether in which the number of ether linkages is 2. http://purl.obolibrary.org/obo/CHEBI_47891 steroid acid http://purl.obolibrary.org/obo/CHEBI_64709 organic acid Any steroid substituted by at least one carboxy group. http://purl.obolibrary.org/obo/CHEBI_47985 enol ether http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound Ethers ROR' where R has a double bond adjacent to the oxygen of the ether linkage. http://purl.obolibrary.org/obo/CHEBI_48356 protic solvent http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent A polar solvent that is capable of acting as a hydron (proton) donor. http://purl.obolibrary.org/obo/CHEBI_48705 agonist http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. http://purl.obolibrary.org/obo/CHEBI_50160 steroid acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion Any anion formed by loss of a proton from a steroid acid. http://purl.obolibrary.org/obo/CHEBI_50177 dermatologic drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug used to treat or prevent skin disorders or for the routine care of skin. http://purl.obolibrary.org/obo/CHEBI_50266 prodrug http://purl.obolibrary.org/obo/CHEBI_23888 drug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. http://purl.obolibrary.org/obo/CHEBI_50525 phenolate anion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion arising from deprotonation of the OH function of a phenol compound. http://purl.obolibrary.org/obo/CHEBI_50683 EC 1.5.1.3 (dihydrofolate reductase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76863 EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3). http://purl.obolibrary.org/obo/CHEBI_50733 nutraceutical http://purl.obolibrary.org/obo/CHEBI_23888 drug A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. http://purl.obolibrary.org/obo/CHEBI_50909 nephrotoxic agent http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by any chemical compound (natural or synthetic) exhibiting itself through the ability to induce damage to the kidneys. http://purl.obolibrary.org/obo/CHEBI_51026 macrocycle http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclic compound containing nine or more atoms as part of the cyclic system. http://purl.obolibrary.org/obo/CHEBI_51217 fluorochrome http://purl.obolibrary.org/obo/CHEBI_51121 fluorescent dye A fluorescent dye used to stain biological specimens. http://purl.obolibrary.org/obo/CHEBI_51336 metal sulfate http://purl.obolibrary.org/obo/CHEBI_24840 inorganic sulfate salt Sulfate salts where the cation is a metal ion. http://purl.obolibrary.org/obo/CHEBI_51702 enoate ester http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound An α,β-unsaturated carboxylic ester of general formula R1R2C=CR3‒C(=O)OR4 (R4 ≠ H) in which the ester C=O function is conjugated to a C=C double bond at the α,β position. http://purl.obolibrary.org/obo/CHEBI_51737 alpha,beta-unsaturated carboxylic ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester A carboxylic ester of general formula R1R2C=CR3‒C(=O)OR4 (R4 ≠ H) or R1C≡C‒C(=O)OR2 (R2 ≠ H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the α,β position. http://purl.obolibrary.org/obo/CHEBI_51751 enamide http://purl.obolibrary.org/obo/CHEBI_51750 alpha,beta-unsaturated carboxylic acid amide An α,β-unsaturated carboxylic acid amide of general formula R1R2C=CR3‒C(=O)NR4R5 in which the amide C=O function is conjugated to a C=C double bond at the α,β position. http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A biological role played by the molecular entity or part thereof within a biochemical context. http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical http://purl.obolibrary.org/obo/CHEBI_33232 application Any substance introduced into a living organism with therapeutic or diagnostic purpose. http://purl.obolibrary.org/obo/CHEBI_52557 tetracyclic diterpenoid http://purl.obolibrary.org/obo/CHEBI_23849 diterpenoid A diterpenoid with a tetracyclic skeleton. http://purl.obolibrary.org/obo/CHEBI_57248 echinocandin http://purl.obolibrary.org/obo/CHEBI_46895 lipopeptide Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-β-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most Candida spp and fungistatic against Aspergillus spp. http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion in which there is no C‒C unsaturation. http://purl.obolibrary.org/obo/CHEBI_59644 oxo fatty acid http://purl.obolibrary.org/obo/CHEBI_25754 oxo carboxylic acid Any fatty acid containing at least one aldehydic or ketonic group in addition to the carboxylic acid group. http://purl.obolibrary.org/obo/CHEBI_59769 acetal http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' ≠ H). Mixed acetals have R'' and R''' groups which differ. http://purl.obolibrary.org/obo/CHEBI_59770 cyclic acetal http://purl.obolibrary.org/obo/CHEBI_24532 organic heterocyclic compound An acetal in the molecule of which the acetal carbon and one or both oxygen atoms thereon are members of a ring. http://purl.obolibrary.org/obo/CHEBI_59779 cyclic ketal http://purl.obolibrary.org/obo/CHEBI_59777 ketal A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring. http://purl.obolibrary.org/obo/CHEBI_59780 cyclic hemiketal http://purl.obolibrary.org/obo/CHEBI_59772 hemiketal A hemiacetal having the structure R2C(OH)OR (R ≠ H), derived from a ketone by formal addition of an alcohol to the carbonyl group. The term 'cyclic hemiketals', once abandoned by IUPAC, has been reinstated as a subclass of hemiacetals. http://purl.obolibrary.org/obo/CHEBI_60004 mixture http://purl.obolibrary.org/obo/CHEBI_59999 chemical substance A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind. http://purl.obolibrary.org/obo/CHEBI_60334 peptide anion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An anion formed by deprotonation of at least one peptide carboxy group. http://purl.obolibrary.org/obo/CHEBI_60926 amino monosaccharide http://purl.obolibrary.org/obo/CHEBI_28963 amino sugar Any amino sugar that is a monosaccharide in which one alcoholic hydroxy group is replaced by an amino group. http://purl.obolibrary.org/obo/CHEBI_61120 nucleobase-containing molecular entity http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene Any compound that has a nucleobase as a part. http://purl.obolibrary.org/obo/CHEBI_61689 amino cyclitol http://purl.obolibrary.org/obo/CHEBI_23451 cyclitol Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups. http://purl.obolibrary.org/obo/CHEBI_62488 signalling molecule http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell. http://purl.obolibrary.org/obo/CHEBI_62643 anionic phospholipid http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1−), phosphatidate(2−), phosphatidylglycerol(1−). http://purl.obolibrary.org/obo/CHEBI_62872 EC 1.2.3.1 (aldehyde oxidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76853 EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1). http://purl.obolibrary.org/obo/CHEBI_63353 disaccharide derivative http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from a disaccharide. http://purl.obolibrary.org/obo/CHEBI_63473 aromatic amino-acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion An aromatic amino acid whose α-carboxylic acid group is ionized (non-protonated). http://purl.obolibrary.org/obo/CHEBI_63944 macrocyclic lactone http://purl.obolibrary.org/obo/CHEBI_51026 macrocycle Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule. http://purl.obolibrary.org/obo/CHEBI_64571 NMDA receptor agonist http://purl.obolibrary.org/obo/CHEBI_50103 excitatory amino acid agonist An excitatory amino acid agonist which binds to NMDA receptors and triggers a response. http://purl.obolibrary.org/obo/CHEBI_64775 organic anionic group http://purl.obolibrary.org/obo/CHEBI_64767 anionic group An anionic group that contains carbon. http://purl.obolibrary.org/obo/CHEBI_64909 poison http://purl.obolibrary.org/obo/CHEBI_24432 biological role Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism. http://purl.obolibrary.org/obo/CHEBI_65212 polysaccharide derivative http://purl.obolibrary.org/obo/CHEBI_167559 glycan A carbohydrate derivative that is any derivative of a polysaccharide. http://purl.obolibrary.org/obo/CHEBI_65255 food preservative http://purl.obolibrary.org/obo/CHEBI_64047 food additive Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes. http://purl.obolibrary.org/obo/CHEBI_65259 GABA antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist A compound that inhibits the action of γ-aminobutyric acid. http://purl.obolibrary.org/obo/CHEBI_65296 primary ammonium ion http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_70727 topoisomerase inhibitor http://purl.obolibrary.org/obo/CHEBI_76830 EC 5.99.1.* (miscellaneous isomerase) inhibitor An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA). http://purl.obolibrary.org/obo/CHEBI_71989 ortho ester http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any organooxygen compound that has the general formula RC(OR1)(OR2)(OR3), where R1, R2, R3 ≠ H. http://purl.obolibrary.org/obo/CHEBI_73216 EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*). http://purl.obolibrary.org/obo/CHEBI_74818 heteroaryl hydroxy compound http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Any organic aromatic compound having one or more hydroxy groups attached to a heteroarene ring. http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite Any animal metabolite produced during a metabolic reaction in mammals. http://purl.obolibrary.org/obo/CHEBI_75769 B vitamin http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B1, B2, B3, B5, B6, B7, B9, and B12 (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such). http://purl.obolibrary.org/obo/CHEBI_76567 polyunsaturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_2580 unsaturated fatty acid anion Any unsaturated fatty acid anion containing more than one C-C unsaturated bond. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor http://purl.obolibrary.org/obo/CHEBI_37699 protein kinase inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*). http://purl.obolibrary.org/obo/CHEBI_76837 EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor http://purl.obolibrary.org/obo/CHEBI_76740 EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*). http://purl.obolibrary.org/obo/CHEBI_76895 EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor http://purl.obolibrary.org/obo/CHEBI_73216 EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*). http://purl.obolibrary.org/obo/CHEBI_77255 EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_59107 EC 3.4.24.* (metalloendopeptidase) inhibitor An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83). http://purl.obolibrary.org/obo/CHEBI_77745 EC 3.4.24.18 (meprin A) inhibitor http://purl.obolibrary.org/obo/CHEBI_59107 EC 3.4.24.* (metalloendopeptidase) inhibitor An EC 3.4.24.* (metalloendopeptidase) inhibitor that inhibits the action of meprin A (EC 3.4.24.18). http://purl.obolibrary.org/obo/CHEBI_77747 EC 3.6.3.1 (phospholipid-translocating ATPase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76895 EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of phospholipid-translocating ATPase (EC 3.6.3.1). http://purl.obolibrary.org/obo/CHEBI_77748 EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76895 EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44). http://purl.obolibrary.org/obo/CHEBI_78608 alpha-amino-acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion An amino acid-zwitterion obtained by transfer of a proton from the carboxy to the amino group of any α-amino acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_83039 crustacean metabolite http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill. http://purl.obolibrary.org/obo/CHEBI_83399 marine xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_76206 xenobiotic metabolite Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms. http://purl.obolibrary.org/obo/CHEBI_83876 cationic sphingoid http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the amino function of any sphingoid http://purl.obolibrary.org/obo/CHEBI_84087 human urinary metabolite http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite Any metabolite (endogenous or exogenous) found in human urine samples. http://purl.obolibrary.org/obo/CHEBI_86327 antifungal drug http://purl.obolibrary.org/obo/CHEBI_35718 antifungal agent Any antifungal agent used to prevent or treat fungal infections in humans or animals. http://purl.obolibrary.org/obo/CHEBI_86328 antifungal agrochemical http://purl.obolibrary.org/obo/CHEBI_33286 agrochemical Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties. http://purl.obolibrary.org/obo/CHEBI_87113 antibiotic antifungal drug http://purl.obolibrary.org/obo/CHEBI_86478 antibiotic antifungal agent Any antibiotic antifungal agent used to treat fungal infections in humans or animals. http://purl.obolibrary.org/obo/CHEBI_87195 dicarboximide fungicide http://purl.obolibrary.org/obo/CHEBI_87200 dicarboximide antifungal agent Any dicarboximide antifungal agent used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_87230 nitrofuran antibiotic http://purl.obolibrary.org/obo/CHEBI_25807 organooxygen heterocyclic antibiotic A member of the class of furans in which the furan ring is substituted by a nitro group and which also has significant antibiotic properties. http://purl.obolibrary.org/obo/CHEBI_20854 ATP synthase inhibitor http://purl.obolibrary.org/obo/CHEBI_25355 mitochondrial respiratory-chain inhibitor A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase. http://purl.obolibrary.org/obo/CHEBI_209807 cefoxitin http://purl.obolibrary.org/obo/CHEBI_72588 semisynthetic derivative A semisynthetic cephamycin antibiotic which, in addition to the methoxy group at the 7α position, has 2-thienylacetamido and carbamoyloxymethyl side-groups. It is resistant to β-lactamase. http://purl.obolibrary.org/obo/CHEBI_22221 acyl group http://purl.obolibrary.org/obo/CHEBI_33247 organic group An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l ≠ 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids. http://purl.obolibrary.org/obo/CHEBI_22323 alkyl group http://purl.obolibrary.org/obo/CHEBI_33248 hydrocarbyl group A univalent group ‒CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom. http://purl.obolibrary.org/obo/CHEBI_22563 anion http://purl.obolibrary.org/obo/CHEBI_24870 ion A monoatomic or polyatomic species having one or more elementary charges of the electron. http://purl.obolibrary.org/obo/CHEBI_22565 ansamycin http://purl.obolibrary.org/obo/CHEBI_24995 lactam A class of macrocyclic lactams that consist of an aromatic (phenyl or naphthyl) or quinonoid (benzoquinone or naphthoquinone) moiety that is bridged by an aliphatic chain. http://purl.obolibrary.org/obo/CHEBI_22645 arenecarboxamide http://purl.obolibrary.org/obo/CHEBI_62733 aromatic amide A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system. http://purl.obolibrary.org/obo/CHEBI_22907 bleomycin http://purl.obolibrary.org/obo/CHEBI_24396 glycopeptide A glycopeptide produced by the bacterium Streptomyces verticillus. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2. http://purl.obolibrary.org/obo/CHEBI_22944 butanediols http://purl.obolibrary.org/obo/CHEBI_23824 diol A diol that is a butanediol or a derivative of a butanediol. http://purl.obolibrary.org/obo/CHEBI_23004 carbamoyl group http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid. http://purl.obolibrary.org/obo/CHEBI_23007 carbohydrate-containing antibiotic http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative Any carbohydrate derivative that exhibits antibiotic activity. http://purl.obolibrary.org/obo/CHEBI_23132 chlorobenzenes http://purl.obolibrary.org/obo/CHEBI_36683 organochlorine compound Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines. http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. http://purl.obolibrary.org/obo/CHEBI_23414 copper(II) sulfate http://purl.obolibrary.org/obo/CHEBI_51336 metal sulfate A metal sulfate compound having copper(2+) as the metal ion. http://purl.obolibrary.org/obo/CHEBI_23503 4-amino-1,2-oxazolidin-3-one http://purl.obolibrary.org/obo/CHEBI_50994 primary amino compound A member of the class of oxazolidines that is isoxazoldin-3-one which is substituted at position 4 by an amino group. http://purl.obolibrary.org/obo/CHEBI_23677 diazole http://purl.obolibrary.org/obo/CHEBI_68452 azole An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring. http://purl.obolibrary.org/obo/CHEBI_24271 glucosamines http://purl.obolibrary.org/obo/CHEBI_24586 hexosamine Any hexosamine that is glucose in which at least one of the hydroxy groups has been replaced by an amino group. http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_50906 role A role played by the molecular entity or part thereof within a biological context. http://purl.obolibrary.org/obo/CHEBI_24470 haloamino acid http://purl.obolibrary.org/obo/CHEBI_83820 non-proteinogenic amino acid Any non-proteinogenic amino acid carrying at least one halo group. http://purl.obolibrary.org/obo/CHEBI_24532 organic heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_33832 organic cyclic compound A cyclic compound having as ring members atoms of carbon and at least of one other element. http://purl.obolibrary.org/obo/CHEBI_24586 hexosamine http://purl.obolibrary.org/obo/CHEBI_60926 amino monosaccharide Any 6-carbon amino monosaccharide with at least one alcoholic hydroxy group replaced by an amino group. http://purl.obolibrary.org/obo/CHEBI_24648 hydroxamic acid anion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion An oxoanion resulting from the removal of a proton from the hydroxy group of any hydroxamic acid. http://purl.obolibrary.org/obo/CHEBI_24651 hydroxides http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH−). http://purl.obolibrary.org/obo/CHEBI_24676 hydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_33853 phenols Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring. http://purl.obolibrary.org/obo/CHEBI_2468 secondary alpha-hydroxy ketone http://purl.obolibrary.org/obo/CHEBI_139588 alpha-hydroxy ketone An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing one hydrogen and one organyl group. Secondary α-hydroxy ketones are also known as acyloins, and are formally derived from reductive coupling of two carboxylic acid groups. http://purl.obolibrary.org/obo/CHEBI_24835 inorganic molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity that contains no carbon. http://purl.obolibrary.org/obo/CHEBI_24859 iodine atom http://purl.obolibrary.org/obo/CHEBI_24473 halogen Chemical element with atomic number 53. http://purl.obolibrary.org/obo/CHEBI_24866 salt http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity A salt is an assembly of cations and anions. http://purl.obolibrary.org/obo/CHEBI_24869 ionophore http://purl.obolibrary.org/obo/CHEBI_38632 membrane transport modulator A compound which can carry specific ions through membranes of cells or organelles. http://purl.obolibrary.org/obo/CHEBI_24870 ion http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity having a net electric charge. http://purl.obolibrary.org/obo/CHEBI_25675 oligomycin http://purl.obolibrary.org/obo/CHEBI_72600 spiroketal Any of the 26-membered ring macrolides produced by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. http://purl.obolibrary.org/obo/CHEBI_25710 organophosphorus compound http://purl.obolibrary.org/obo/CHEBI_33285 heteroorganic entity An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters. http://purl.obolibrary.org/obo/CHEBI_25741 oxide http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity An oxide is a chemical compound of oxygen with other chemical elements. http://purl.obolibrary.org/obo/CHEBI_25901 pentose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose). http://purl.obolibrary.org/obo/CHEBI_25940 peroxides http://purl.obolibrary.org/obo/CHEBI_25741 oxide Compounds of structure ROOR'. http://purl.obolibrary.org/obo/CHEBI_25944 pesticide http://purl.obolibrary.org/obo/CHEBI_33232 application Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. http://purl.obolibrary.org/obo/CHEBI_26020 phosphate http://purl.obolibrary.org/obo/CHEBI_26079 phosphoric acid derivative Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom. http://purl.obolibrary.org/obo/CHEBI_26167 polar amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid Any amino acid whose side chain is capable of forming one or more hydrogen bonds. http://purl.obolibrary.org/obo/CHEBI_26177 polyene antibiotic http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound A family of antibiotics containing a conjugated polyene moiety, usuallly isolated from some species of Streptomyces. http://purl.obolibrary.org/obo/CHEBI_2634 amidine http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine. http://purl.obolibrary.org/obo/CHEBI_2637 amikacin http://purl.obolibrary.org/obo/CHEBI_22479 amino cyclitol glycoside An amino cyclitol glycoside that is kanamycin A acylated at the N-1 position by a 4-amino-2-hydroxybutyryl group. http://purl.obolibrary.org/obo/CHEBI_26395 purine nucleotide http://purl.obolibrary.org/obo/CHEBI_26401 purines Any nucleotide that has a purine nucleobase. http://purl.obolibrary.org/obo/CHEBI_26400 purine ribonucleotide http://purl.obolibrary.org/obo/CHEBI_26395 purine nucleotide Any ribonucleotide that has a purine nucleobase. http://purl.obolibrary.org/obo/CHEBI_26469 quaternary nitrogen compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen. http://purl.obolibrary.org/obo/CHEBI_26710 sodium chloride http://purl.obolibrary.org/obo/CHEBI_36093 inorganic chloride An inorganic chloride salt having sodium(1+) as the counterion. http://purl.obolibrary.org/obo/CHEBI_26714 sodium salt http://purl.obolibrary.org/obo/CHEBI_35479 alkali metal salt Any alkali metal salt having sodium(1+) as the cation. http://purl.obolibrary.org/obo/CHEBI_26820 sulfates http://purl.obolibrary.org/obo/CHEBI_37826 sulfuric acid derivative Salts and esters of sulfuric acid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid http://purl.obolibrary.org/obo/CHEBI_24913 isoprenoid Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group. http://purl.obolibrary.org/obo/CHEBI_27561 oxirane http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. http://purl.obolibrary.org/obo/CHEBI_27641 cycloheximide http://purl.obolibrary.org/obo/CHEBI_49318 piperidine antibiotic A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. http://purl.obolibrary.org/obo/CHEBI_27656 camptothecin http://purl.obolibrary.org/obo/CHEBI_48626 pyranoindolizinoquinoline A pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). http://purl.obolibrary.org/obo/CHEBI_28201 rotenone http://purl.obolibrary.org/obo/CHEBI_38164 organic heteropentacyclic compound A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica). http://purl.obolibrary.org/obo/CHEBI_28240 dichloroacetate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of dichloroacetic acid. http://purl.obolibrary.org/obo/CHEBI_28368 novobiocin http://purl.obolibrary.org/obo/CHEBI_37912 hydroxycoumarin A coumarin-derived antibiotic obtained from Streptomyces niveus. http://purl.obolibrary.org/obo/CHEBI_28669 bacitracin http://purl.obolibrary.org/obo/CHEBI_60004 mixture A mixture of at least nine closely related homodetic cyclic peptides produced by Bacillus subtilis and B. licheniformis, which is particularly active against Gram-positive bacteria. http://purl.obolibrary.org/obo/CHEBI_28864 tobramycin http://purl.obolibrary.org/obo/CHEBI_22479 amino cyclitol glycoside A amino cyclitol glycoside that is kanamycin B lacking the 3-hydroxy substituent from the 2,6-diaminoglucose ring. http://purl.obolibrary.org/obo/CHEBI_28909 iprodione http://purl.obolibrary.org/obo/CHEBI_47857 ureas An imidazolidine-2,4-dione in which the nitrogen at position 1 is substituted by an N-(isopropyl)carboxamide group while that at position 3 is substituted by a 3,5-dichlorophenyl group. A contact fungicide, it blocks the growth of the fungal mycelium and inhibits the germination of fungal spores. It is used on fruit and vegetable crops affected by various fungal diseases. It is also used as a nematicide. http://purl.obolibrary.org/obo/CHEBI_28915 fosfomycin http://purl.obolibrary.org/obo/CHEBI_32955 epoxide A phosphonic acid having an (R,S)-1,2-epoxypropyl group attached to phosphorus. http://purl.obolibrary.org/obo/CHEBI_28963 amino sugar http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups. http://purl.obolibrary.org/obo/CHEBI_28971 ampicillin http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-phenylacetamido group. http://purl.obolibrary.org/obo/CHEBI_29007 ceftriaxone http://purl.obolibrary.org/obo/CHEBI_39410 1,2,4-triazines A third-generation cephalosporin compound having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups. http://purl.obolibrary.org/obo/CHEBI_29013 fusidic acid http://purl.obolibrary.org/obo/CHEBI_19129 11alpha-hydroxy steroid A steroid antibiotic that is isolated from the fermentation broth of Fusidium coccineum. http://purl.obolibrary.org/obo/CHEBI_29036 copper(2+) http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation An ion of copper carrying a double positive charge. http://purl.obolibrary.org/obo/CHEBI_29101 sodium(1+) http://purl.obolibrary.org/obo/CHEBI_37246 elemental sodium A monoatomic monocation obtained from sodium. http://purl.obolibrary.org/obo/CHEBI_29103 potassium(1+) http://purl.obolibrary.org/obo/CHEBI_37247 elemental potassium A monoatomic monocation obtained from potassium. http://purl.obolibrary.org/obo/CHEBI_30347 ethylenediamine http://purl.obolibrary.org/obo/CHEBI_35411 alkane-alpha,omega-diamine An alkane-α,ω-diamine in which the alkane is ethane. http://purl.obolibrary.org/obo/CHEBI_30802 isophthalic acid http://purl.obolibrary.org/obo/CHEBI_26094 benzenedicarboxylic acid A benzenedicarboxylic acid that is benzene substituted by carboxy groups at position 1 and 3. One of three possible isomers of benzenedicarboxylic acid, the others being phthalic and terephthalic acids. http://purl.obolibrary.org/obo/CHEBI_32871 prolinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An α-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_32872 prolinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An α-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group. http://purl.obolibrary.org/obo/CHEBI_32988 amide http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l ≠ 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/CHEBI_33232 application http://purl.obolibrary.org/obo/CHEBI_50906 role Intended use of the molecular entity or part thereof by humans. http://purl.obolibrary.org/obo/CHEBI_33238 monoatomic entity http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity A monoatomic entity is a molecular entity consisting of a single atom. http://purl.obolibrary.org/obo/CHEBI_33240 coordination entity http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands). http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_37175 organic hydride An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system. http://purl.obolibrary.org/obo/CHEBI_33248 hydrocarbyl group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group A univalent group formed by removing a hydrogen atom from a hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A chemical entity constituting the smallest component of an element having the chemical properties of the element. http://purl.obolibrary.org/obo/CHEBI_33253 nucleon http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle Heavy nuclear particle: proton or neutron. http://purl.obolibrary.org/obo/CHEBI_33257 secondary amide http://purl.obolibrary.org/obo/CHEBI_32988 amide A derivative of two oxoacids RkE(=O)l(OH)m (l ≠ 0) in which two acyl groups are attached to the amino or substituted amino group. http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity all atoms of which have the same atomic number. http://purl.obolibrary.org/obo/CHEBI_33285 heteroorganic entity http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms. http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity A molecular entity containing one or more atoms of an alkali metal. http://purl.obolibrary.org/obo/CHEBI_33300 pnictogen http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth. http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity A p-block molecular entity containing any pnictogen. http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom Any p-block element belonging to the group 16 family of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity Any p-block molecular entity containing a chalcogen. http://purl.obolibrary.org/obo/CHEBI_33318 main group element atom http://purl.obolibrary.org/obo/CHEBI_33250 atom An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33521 metal atom http://purl.obolibrary.org/obo/CHEBI_33250 atom An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity. http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_33318 main group element atom Any main group element atom belonging to the p-block of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33598 carbocyclic compound http://purl.obolibrary.org/obo/CHEBI_33597 homocyclic compound A homocyclic compound in which all of the ring members are carbon atoms. http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity A main group molecular entity that contains one or more atoms of a p-block element. http://purl.obolibrary.org/obo/CHEBI_33832 organic cyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound Any organic molecule that consists of atoms connected in the form of a ring. http://purl.obolibrary.org/obo/CHEBI_33937 macronutrient http://purl.obolibrary.org/obo/CHEBI_33284 nutrient Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals. http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion http://purl.obolibrary.org/obo/CHEBI_33273 polyatomic anion An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen. http://purl.obolibrary.org/obo/CHEBI_35410 primary diamine http://purl.obolibrary.org/obo/CHEBI_23666 diamine A primary diamine is a compound derived from a hydrocarbon by replacing two hydrogen atoms by amino groups. http://purl.obolibrary.org/obo/CHEBI_35785 sphingoid http://purl.obolibrary.org/obo/CHEBI_26739 sphingolipid Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds. http://purl.obolibrary.org/obo/CHEBI_35903 oxo carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion Any carboxylic acid anion containing at least one oxo group. http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. http://purl.obolibrary.org/obo/CHEBI_35992 penams http://purl.obolibrary.org/obo/CHEBI_38106 organosulfur heterocyclic compound Natural and synthetic antibiotics containing the 4-thia-1-azabicyclo[3.2.0]heptan-7-one structure, generally assumed to have the 5R configuration unless otherwise specified. http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity Any molecular entity consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_36358 polyatomic ion http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity An ion consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_36386 dichloroacetic acid http://purl.obolibrary.org/obo/CHEBI_36683 organochlorine compound An organochlorine compound comprising acetic acid carrying two chloro substituents at the 2-position. It occurs in nature in seaweed, Asparagopsis taxiformis. http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_24870 ion A monoatomic or polyatomic species having one or more elementary charges of the proton. http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity An organochalcogen compound is a compound containing at least one carbon-chalcogen bond. http://purl.obolibrary.org/obo/CHEBI_37206 hexol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A polyol that contains 6 hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_37533 azo compound http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity Derivatives of diazene with the general structure R‒N=N‒R'. http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity A molecular entity consisting of two or more chemical elements. http://purl.obolibrary.org/obo/CHEBI_37670 protease inhibitor http://purl.obolibrary.org/obo/CHEBI_60258 EC 3.4.* (hydrolases acting on peptide bond) inhibitor A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). http://purl.obolibrary.org/obo/CHEBI_37838 carboacyl group http://purl.obolibrary.org/obo/CHEBI_22221 acyl group A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_38632 membrane transport modulator http://purl.obolibrary.org/obo/CHEBI_52208 biophysical role Any agent that affects the transport of molecular entities across a biological membrane. http://purl.obolibrary.org/obo/CHEBI_38773 quinolinemonocarboxylate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the monoanion obtained by the deprotonation of the carboxy group attached to the quinoline skeleton http://purl.obolibrary.org/obo/CHEBI_39141 Bronsted acid http://purl.obolibrary.org/obo/CHEBI_37527 acid A molecular entity capable of donating a hydron to an acceptor (Brønsted base). http://purl.obolibrary.org/obo/CHEBI_39317 growth regulator http://purl.obolibrary.org/obo/CHEBI_24432 biological role Any chemical substance that inhibits the life-cycle of an organism. http://purl.obolibrary.org/obo/CHEBI_39745 dihydrogenphosphate http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated. http://purl.obolibrary.org/obo/CHEBI_42266 ethane http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity An alkane comprising of two carbon atoms. http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid. http://purl.obolibrary.org/obo/CHEBI_51422 organodiyl group http://purl.obolibrary.org/obo/CHEBI_51446 organic divalent group Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s). http://purl.obolibrary.org/obo/CHEBI_53655 cefoxitin(1-) http://purl.obolibrary.org/obo/CHEBI_52440 cephalosporin carboxylic acid anion A cephalosporin carboxylic acid anion having methoxy, 2-thienylacetamido and carbamoyloxymethyl side-groups, formed by proton loss from the carboxy group of the semisynthetic cephamycin antibiotic cefoxitin. http://purl.obolibrary.org/obo/CHEBI_53670 cefotaxime(1-) http://purl.obolibrary.org/obo/CHEBI_52440 cephalosporin carboxylic acid anion A cephalosporin carboxylic acid anion having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side-groups, formed by proton loss from the carboxy group of the cephalosporin cefotaxime. http://purl.obolibrary.org/obo/CHEBI_55429 cephamycin http://purl.obolibrary.org/obo/CHEBI_38311 cephem Any member of the cephamycin sub-group of cephem antibiotics, differing from cephalosporins in possessing a methoxy group at the 7α-position of the cephem nucleus, and in being resistant to β-lactamase. http://purl.obolibrary.org/obo/CHEBI_59650 amino fatty acid http://purl.obolibrary.org/obo/CHEBI_60690 nitrogen-containing fatty acid A fatty acid containing at least one amino substituent. http://purl.obolibrary.org/obo/CHEBI_59672 EC 2.4.1.16 (chitin synthase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76789 EC 2.4.1.* (hexosyltransferase) inhibitor A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of chitin synthase (EC 2.4.1.16). http://purl.obolibrary.org/obo/CHEBI_59698 phosphoric acids http://purl.obolibrary.org/obo/CHEBI_33457 phosphorus oxoacid Compounds containing one or more phosphoric acid units. http://purl.obolibrary.org/obo/CHEBI_59831 enyne http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound An acetylenic and an olefinic compound containing a carbon chain that contains a carbon-carbon double bond and a carbon-carbon triple bond. http://purl.obolibrary.org/obo/CHEBI_60979 alpha-glucoside http://purl.obolibrary.org/obo/CHEBI_24278 glucoside A glucoside in which the anomeric carbon of the glycosidic bond is in an α configuration http://purl.obolibrary.org/obo/CHEBI_63161 glycosyl compound http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity. http://purl.obolibrary.org/obo/CHEBI_64912 antimycobacterial drug http://purl.obolibrary.org/obo/CHEBI_36047 antibacterial drug A drug used to treat or prevent infections caused by Mycobacteria, a genus of actinobacteria. Aerobic and nonmotile, members of the genus include the pathogens responsible for causing tuberculosis and leprosy. http://purl.obolibrary.org/obo/CHEBI_68452 azole http://purl.obolibrary.org/obo/CHEBI_38179 monocyclic heteroarene Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen. http://purl.obolibrary.org/obo/CHEBI_75606 hydroxamic acid ester http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A carboxamide that is a hydroxamic acid in which the hydrogen of the hydroxy group is replaced by an organyl group. http://purl.obolibrary.org/obo/CHEBI_76907 EC 4.2.1.* (hydro-lyases) inhibitor http://purl.obolibrary.org/obo/CHEBI_76712 EC 4.2.* (C-O lyase) inhibitor An EC 4.2.* (C‒O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*). http://purl.obolibrary.org/obo/CHEBI_83811 proteinogenic amino acid derivative http://purl.obolibrary.org/obo/CHEBI_83821 amino-acid derivative Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom. http://purl.obolibrary.org/obo/CHEBI_83820 non-proteinogenic amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid Any amino-acid that is not naturally encoded in the genetic code of any organism. http://purl.obolibrary.org/obo/CHEBI_84055 pentose phosphate http://purl.obolibrary.org/obo/CHEBI_33447 phospho sugar Any phospho sugar that is the phosphate derivative of pentose. http://purl.obolibrary.org/obo/CHEBI_84739 amikacin(4+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the four free amino groups of amikacin; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_88061 polyamine http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound Any organic amino compound that contains two or more amino groups. http://purl.obolibrary.org/obo/CHEBI_88227 potassium ionophore http://purl.obolibrary.org/obo/CHEBI_24869 ionophore Any ionophore capable of transportation of potassium ions across membranes. http://purl.obolibrary.org/obo/CHEBI_37153 EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76775 EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16). http://purl.obolibrary.org/obo/CHEBI_3732 clarithromycin http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic The 6-O-methyl ether of erythromycin A, clarithromycin is a macrolide antibiotic used in the treatment of respiratory-tract, skin and soft-tissue infections. It is also used to eradicate Helicobacter pylori in the treatment of peptic ulcer disease. It prevents bacteria from growing by interfering with their protein synthesis. http://purl.obolibrary.org/obo/CHEBI_3745 clindamycin http://purl.obolibrary.org/obo/CHEBI_35275 S-glycosyl compound A carbohydrate-containing antibiotic that is the semisynthetic derivative of lincomycin, a natural antibiotic. http://purl.obolibrary.org/obo/CHEBI_37627 L-glucopyranose http://purl.obolibrary.org/obo/CHEBI_37661 glucopyranose The L-enantiomer of glucopyranose. http://purl.obolibrary.org/obo/CHEBI_38127 thiocarbamic ester http://purl.obolibrary.org/obo/CHEBI_26959 thiocarboxylic ester Any organonitrogen compound with formula RS-C(=X)NH2 where X = O (monothiocarbamic esters) or S (dithiocarbamic esters), or their N-substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_38129 dithiocarbamic ester http://purl.obolibrary.org/obo/CHEBI_38127 thiocarbamic ester Any ester derived from a member of the class of dithiocarbamic acids by formal replacement of the -SH group by -SR, where R is an organyl group. http://purl.obolibrary.org/obo/CHEBI_38313 diazines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure). http://purl.obolibrary.org/obo/CHEBI_38503 EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor http://purl.obolibrary.org/obo/CHEBI_76866 EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H+-translocating), EC 1.6.5.3. http://purl.obolibrary.org/obo/CHEBI_39142 Bronsted base http://purl.obolibrary.org/obo/CHEBI_22695 base A molecular entity capable of accepting a hydron from a donor (Brønsted acid). http://purl.obolibrary.org/obo/CHEBI_39144 Lewis base http://purl.obolibrary.org/obo/CHEBI_22695 base A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct. http://purl.obolibrary.org/obo/CHEBI_39214 abamectin http://purl.obolibrary.org/obo/CHEBI_39219 avermectin acaricide Mixture of 80% avermectin B1a and 20% avermectin B1b. http://purl.obolibrary.org/obo/CHEBI_39230 emamectin http://purl.obolibrary.org/obo/CHEBI_39213 avermectin insecticide A mixture of emamectin B1a (major component) and emamectin B1b (minor component). http://purl.obolibrary.org/obo/CHEBI_5653 hemiacetal http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A compound having the general formula RR'C(OH)OR'' (R'' ≠ H). http://purl.obolibrary.org/obo/CHEBI_60258 EC 3.4.* (hydrolases acting on peptide bond) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*). http://purl.obolibrary.org/obo/CHEBI_6472 lincomycin http://purl.obolibrary.org/obo/CHEBI_84186 L-proline derivative A carbohydrate-containing antibiotic produced by the actinomyces Streptomyces lincolnensis. http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*). http://purl.obolibrary.org/obo/CHEBI_76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76760 EC 3.1.* (ester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*). http://purl.obolibrary.org/obo/CHEBI_76815 EC 2.7.7.* (nucleotidyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*). http://purl.obolibrary.org/obo/CHEBI_76861 EC 1.4.3.* (oxidoreductase acting on donor CH-NH2 group, oxygen as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76730 EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor An EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.4.3.*). http://purl.obolibrary.org/obo/CHEBI_76866 EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76733 EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*). http://purl.obolibrary.org/obo/CHEBI_76870 EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76736 EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*). http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor that interferes with one or more steps in a metabolic pathway. http://purl.obolibrary.org/obo/CHEBI_87067 conazole fungicide http://purl.obolibrary.org/obo/CHEBI_86323 conazole antifungal agent Any conazole antifungal agent that has been used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_4885 ethionamide http://purl.obolibrary.org/obo/CHEBI_47956 thiocarboxamide A thiocarboxamide that is pyridine-4-carbothioamide substituted by an ethyl group at position 2. A prodrug that undergoes metabolic activation by conversion to the corresponding S-oxide. http://purl.obolibrary.org/obo/CHEBI_4998 fenarimol http://purl.obolibrary.org/obo/CHEBI_60911 racemate A racemate comprising equimolar amounts of (R)- and (S)-fenarimol. A sterol demethylation inhibitor, it is used as a fungicide for the treatment of blackspot, mildew and rust in tomatoes, peppers and melons, but is not approved for use within the European Union. http://purl.obolibrary.org/obo/CHEBI_50010 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid http://purl.obolibrary.org/obo/CHEBI_33551 organosulfonic acid An organosulfonic acid comprising stilbene having 4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino groups at the 4 and 4'-positions and sulfo groups at the 2- and 2'-positions. http://purl.obolibrary.org/obo/CHEBI_50012 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonate http://purl.obolibrary.org/obo/CHEBI_22713 arenesulfonate oxoanion An arenesulfonate arising from deprotonation of the sulfo groups of 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid. http://purl.obolibrary.org/obo/CHEBI_50685 antitrichomonal drug http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug A drug used to treat trichomonas infections. http://purl.obolibrary.org/obo/CHEBI_5100 flucytosine http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections. http://purl.obolibrary.org/obo/CHEBI_51061 hormone receptor modulator http://purl.obolibrary.org/obo/CHEBI_90710 receptor modulator A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A role played by the molecular entity or part thereof which causes the development of a pathological process. http://purl.obolibrary.org/obo/CHEBI_64290 erythromycin cation http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of any erythromycin. http://purl.obolibrary.org/obo/CHEBI_70728 actin polymerisation inhibitor http://purl.obolibrary.org/obo/CHEBI_35222 inhibitor Any substance that inhibits the polymerisation of the protein actin. http://purl.obolibrary.org/obo/CHEBI_71337 minocycline(1-) http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the conjugate base of minocycline, obtained by deprotonation of the two enolic hydroxy groups and protonation of the non-aromatic tertiary amino group. http://purl.obolibrary.org/obo/CHEBI_73913 antifolate http://purl.obolibrary.org/obo/CHEBI_35221 antimetabolite An antimetabolite that impairs the action of folic acids http://purl.obolibrary.org/obo/CHEBI_76760 EC 3.1.* (ester hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*). http://purl.obolibrary.org/obo/CHEBI_76838 EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*). http://purl.obolibrary.org/obo/CHEBI_76857 EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76729 EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD+ or NADP+ as acceptor (EC 1.3.1.*). http://purl.obolibrary.org/obo/CHEBI_76863 EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76731 EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD+ or NADP+ as acceptor (EC 1.5.1.*). http://purl.obolibrary.org/obo/CHEBI_76881 EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*). http://purl.obolibrary.org/obo/CHEBI_76898 EC 1.14.14.1 (unspecific monooxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76838 EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1). http://purl.obolibrary.org/obo/CHEBI_77906 minocycline zwitterion http://purl.obolibrary.org/obo/CHEBI_144644 a tetracycline zwitterion A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of minocycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_7809 oxacillin http://purl.obolibrary.org/obo/CHEBI_17334 penicillin A penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6β. http://purl.obolibrary.org/obo/CHEBI_83060 dithiocarbamate salt http://purl.obolibrary.org/obo/CHEBI_24868 organic salt Any salt derived from a member of the class of dithiocarbamic acids by the formal replacement of the hydrogen of the dithiocarboxy group by a metal. http://purl.obolibrary.org/obo/CHEBI_83317 sterol biosynthesis inhibitor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any compound that inhibits the biosynthesis of any sterol. http://purl.obolibrary.org/obo/CHEBI_83319 EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76857 EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of Δ14-sterol reductase (EC 1.3.1.70). http://purl.obolibrary.org/obo/CHEBI_83688 (R)-fenarimol http://purl.obolibrary.org/obo/CHEBI_83686 (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has R configuration. http://purl.obolibrary.org/obo/CHEBI_83689 (S)-fenarimol http://purl.obolibrary.org/obo/CHEBI_83686 (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol A (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol that has S configuration. http://purl.obolibrary.org/obo/CHEBI_84291 organic sulfur anion http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity An organic anion in which the charge resides on a sulfur atom. http://purl.obolibrary.org/obo/CHEBI_87134 morpholine fungicide http://purl.obolibrary.org/obo/CHEBI_87132 morpholine antifungal agent Any morpholine antifungal agent used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_87205 pyrimidine antifungal drug http://purl.obolibrary.org/obo/CHEBI_87204 pyrimidine antifungal agent Any pyrimidine antifungal agent that has been used for the treatment of fungal infections in humans or animals. http://purl.obolibrary.org/obo/CHEBI_87207 pyrimidine fungicide http://purl.obolibrary.org/obo/CHEBI_87204 pyrimidine antifungal agent Any pyrimidine antifungal agent that has been used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_90710 receptor modulator http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors. http://purl.obolibrary.org/obo/CHEBI_6030 isoniazide http://purl.obolibrary.org/obo/CHEBI_35363 carbohydrazide A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine. http://purl.obolibrary.org/obo/CHEBI_6076 itraconazole http://purl.obolibrary.org/obo/CHEBI_87101 triazole antifungal drug An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(±)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis. http://purl.obolibrary.org/obo/CHEBI_60798 excitatory amino acid antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist Any substance which inhibits the action of receptors for excitatory amino acids. http://purl.obolibrary.org/obo/CHEBI_61008 nitrogen-containing fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion A fatty acid anion arising from deprotonation of the carboxylic acid group of any nitrogen-containing fatty acid. http://purl.obolibrary.org/obo/CHEBI_61293 adenyl nucleotide http://purl.obolibrary.org/obo/CHEBI_26395 purine nucleotide A nucleotide having adenine as the base. http://purl.obolibrary.org/obo/CHEBI_61739 aureobasidin A http://purl.obolibrary.org/obo/CHEBI_35213 cyclodepsipeptide A cyclodepsipeptide antibiotic, which is isolated from the filamentous fungus Aureobasidium pullulans R106 and is toxic to yeast at low concentrations (0.1-0.5 ug/ml). http://purl.obolibrary.org/obo/CHEBI_61774 inositol phosphorylceramide synthase inhibitor http://purl.obolibrary.org/obo/CHEBI_76881 EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase. http://purl.obolibrary.org/obo/CHEBI_62220 pyocyanine(1+) http://purl.obolibrary.org/obo/CHEBI_25697 organic cation An organic cation resulting from the protonation of pyocyanin. http://purl.obolibrary.org/obo/CHEBI_62419 (1R,2S)-epoxypropylphosphonate(2-) http://purl.obolibrary.org/obo/CHEBI_71285 organophosphonate(2-) An organophosphonate oxoanion obtained by deprotonation of the two phosphonate OH groups of (1R,2S)-epoxypropylphosphonic acid. http://purl.obolibrary.org/obo/CHEBI_76730 EC 1.4.* (oxidoreductase acting on donor CH-NH2 group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH‒NH2 group of donors (EC 1.4.*.*). http://purl.obolibrary.org/obo/CHEBI_86323 conazole antifungal agent http://purl.obolibrary.org/obo/CHEBI_68452 azole A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. http://purl.obolibrary.org/obo/CHEBI_87012 amide antifungal agent http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A compound that has significant antifungal properties whose structure contains an amide moiety. http://purl.obolibrary.org/obo/CHEBI_63409 pentose derivative http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative A monosaccharide derivative that is formally obtained from a pentose. http://purl.obolibrary.org/obo/CHEBI_63598 levofloxacin http://purl.obolibrary.org/obo/CHEBI_194135 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid An optically active form of ofloxacin having (S)-configuration; an inhibitor of bacterial topoisomerase IV and DNA gyrase. http://purl.obolibrary.org/obo/CHEBI_63607 linezolid http://purl.obolibrary.org/obo/CHEBI_55374 oxazolidinone An organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex. http://purl.obolibrary.org/obo/CHEBI_63611 moxifloxacin http://purl.obolibrary.org/obo/CHEBI_51454 cyclopropanes A quinolone that consists of 4-oxo-1,4-dihydroquinoline-3-carboxylic acid bearing a cyclopropyl substituent at position 1, a fluoro substitiuent at position 6, a (4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl group at position 7 and a methoxy substituent at position 8. A member of the fluoroquinolone class of antibacterial agents. http://purl.obolibrary.org/obo/CHEBI_63673 chemokine receptor 5 antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist An antogonist that blocks chemokine receptor 5 (CCR5). http://purl.obolibrary.org/obo/CHEBI_63697 pyrrolidinopiperidine http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound Any organic heterobicyclic compound containing ortho-fused pyrrolidine and piperidine rings. http://purl.obolibrary.org/obo/CHEBI_63699 moxifloxacinium(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of moxifloxacin. http://purl.obolibrary.org/obo/CHEBI_63951 estrogen receptor agonist http://purl.obolibrary.org/obo/CHEBI_48705 agonist An agonist at the estrogen receptor. http://purl.obolibrary.org/obo/CHEBI_76662 EC 2.4.* (glycosyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*). http://purl.obolibrary.org/obo/CHEBI_76790 EC 2.4.2.* (pentosyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76662 EC 2.4.* (glycosyltransferase) inhibitor An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*). http://purl.obolibrary.org/obo/CHEBI_76853 EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76727 EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*). http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor that inhibits the action of a transferase (EC 2.*) http://purl.obolibrary.org/obo/CHEBI_76830 EC 5.99.1.* (miscellaneous isomerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76697 EC 5.99.* (other isomerases) inhibitor An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class. http://purl.obolibrary.org/obo/CHEBI_71415 nitrofurantoin http://purl.obolibrary.org/obo/CHEBI_87230 nitrofuran antibiotic An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA. http://purl.obolibrary.org/obo/CHEBI_71543 rotenoid http://purl.obolibrary.org/obo/CHEBI_72579 tetrahydrochromenochromene Members of the class of tetrahydrochromenochromene that consists of a cis-fused tetrahydrochromeno[3,4-b]chromene skeleton and its substituted derivatives. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds. http://purl.obolibrary.org/obo/CHEBI_71629 nisin http://purl.obolibrary.org/obo/CHEBI_71645 type A lantibiotic A type-A lantibiotic containing 34 amino acid residues (including lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb)) and five thioether bridges. It is obtained by fermentation of the bacterium Lactococcus lactis and shows particular activity against Clostridium botulinum. It is used in the production of various processed foods to suppress Gram-positive spoilage and pathogenic bacteria and so extend shelf life. http://purl.obolibrary.org/obo/CHEBI_71644 lantibiotic http://purl.obolibrary.org/obo/CHEBI_25903 peptide antibiotic A class of peptide antibiotic characterised by the presence of the rare thioether amino acids lanthionine or methyllanthionine, as well as the unsaturated amino acids dehydroalanine and 2-aminoisobutyric acid. In contrast to classical peptide antibiotics, lantibiotics are synthesised from precursor genes using the ribosomal pathway and the characteristic rare amino acids are introduced by posttranslational modification procedues into the lantibiotic precursor peptides ('prepeptides'). Lantibiotics are subdivided into two types: type A have long, flexible structures, while type B have rigid, globular structures. http://purl.obolibrary.org/obo/CHEBI_71645 type A lantibiotic http://purl.obolibrary.org/obo/CHEBI_71644 lantibiotic Any lantibiotic which has which has a long, flexible structure. http://purl.obolibrary.org/obo/CHEBI_72579 tetrahydrochromenochromene http://purl.obolibrary.org/obo/CHEBI_133135 chromenochromene Any chromenochromene resulting from the formal cis-fusion of two dihydro chromene rings, together with their substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_75381 EC 1.11.1.* (peroxidases) inhibitor http://purl.obolibrary.org/obo/CHEBI_76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*). http://purl.obolibrary.org/obo/CHEBI_79092 EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor http://purl.obolibrary.org/obo/CHEBI_76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any such enzyme using H2O2 as acceptor and incorporating one oxygen atom of the H2O2 into the product (EC 1.11.2.*). http://purl.obolibrary.org/obo/CHEBI_81758 cyproconazole http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide A diastereoisomeric mixture composed of the enantiomeric pair (2R,3S)- and (2S,3R)-cyproconazole in ratio 1:1 with the enantiomeric pair (2R,3R)- and (2S,3S)-cyproconazole. A broad spectrum fungicide, it is used on cereals and other field crops used to control Septoria, rust, powdery mildew and other diseases. http://purl.obolibrary.org/obo/CHEBI_81760 difenoconazole http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide A member of the class of dioxolanes that is 1,3-dioxolane substituted at position 2 by 2-chloro-4-(4-chlorophenoxy)phenyl and 1,2,4-triazol-1-ylmethyl groups. A broad spectrum fungicide with novel broad-range activity used as a spray or seed treatment. It is moderately toxic to humans, mammals, birds and most aquatic organisms. http://purl.obolibrary.org/obo/CHEBI_81763 fludioxonil http://purl.obolibrary.org/obo/CHEBI_38298 benzodioxoles A member of the class of benzodioxoles that is 2,2-difluoro-1,3-benzodioxole substituted at position 4 by a 3-cyanopyrrol-4-yl group. A fungicide seed treatment for control of a range of diseases including Fusarium, Rhizoctonia and Alternaria . http://purl.obolibrary.org/obo/CHEBI_81781 tebuconazole http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops. http://purl.obolibrary.org/obo/CHEBI_81822 boscalid http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes A pyridinecarboxamide obtained by formal condensation of the carboxy group of 2-chloronicotinic acid with the amino group of 4'-chlorobiphenyl-2-amine. A fungicide active against a broad range of fungal pathogens including Botrytis spp., Alternaria spp. and Sclerotinia spp. for use on a wide range of crops including fruit, vegetables and ornamentals. http://purl.obolibrary.org/obo/CHEBI_81853 fenhexamid http://purl.obolibrary.org/obo/CHEBI_62733 aromatic amide An aromatic amide resulting from the formal condensation of the carboxy group of 1-methylcyclohexanecarboxylic acid with the amino group of 4-amino-2,3-dichlorophenol. http://purl.obolibrary.org/obo/CHEBI_81913 diniconazole http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide A racemate comprising equimolar amounts of (R)- and (S)-diniconazole. A fungicide used to control a range of diseases including mildew, bunts and smuts. http://purl.obolibrary.org/obo/CHEBI_81917 fenpropidin http://purl.obolibrary.org/obo/CHEBI_60911 racemate A racemate comprising equimolar amounts of (R)- and (S)-fenpropidin. A systemic fungicide, it is used for the control of foliar diseases in cereals and sugar beet. http://purl.obolibrary.org/obo/CHEBI_81923 flutriafol http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide A racemate comprising an equimolar mixture of (R)- and (S)-flutriafol. A systemic fungicide, it is used to control fungal diseases in cereal crops. http://purl.obolibrary.org/obo/CHEBI_8273 plumbagin http://purl.obolibrary.org/obo/CHEBI_33853 phenols A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively. http://purl.obolibrary.org/obo/CHEBI_82892 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole http://purl.obolibrary.org/obo/CHEBI_24780 imidazoles A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group. http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite http://purl.obolibrary.org/obo/CHEBI_83039 crustacean metabolite A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia http://purl.obolibrary.org/obo/CHEBI_83293 (R)-fenpropidin http://purl.obolibrary.org/obo/CHEBI_83291 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine A 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine that has R configuration. http://purl.obolibrary.org/obo/CHEBI_83294 (S)-fenpropidin http://purl.obolibrary.org/obo/CHEBI_83291 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine A 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine that has S configuration. http://purl.obolibrary.org/obo/CHEBI_83316 EC 1.14.13.72 (methylsterol monooxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76841 EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of methylsterol monooxygenase (EC 1.14.13.72). http://purl.obolibrary.org/obo/CHEBI_83749 (2R,3S)-cyproconazole http://purl.obolibrary.org/obo/CHEBI_83748 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol The (2R,3S)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. http://purl.obolibrary.org/obo/CHEBI_83750 (2S,3S)-cyproconazole http://purl.obolibrary.org/obo/CHEBI_83748 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol The (2S,3S)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. http://purl.obolibrary.org/obo/CHEBI_83752 (2S,3R)-cyproconazole http://purl.obolibrary.org/obo/CHEBI_83748 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol The (2S,3R)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. http://purl.obolibrary.org/obo/CHEBI_83753 (2R,3R)-cyproconazole http://purl.obolibrary.org/obo/CHEBI_83748 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol The (2R,3R)-stereoisomer of 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. http://purl.obolibrary.org/obo/CHEBI_83780 (S)-tebuconazole http://purl.obolibrary.org/obo/CHEBI_83779 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol The (S)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol. http://purl.obolibrary.org/obo/CHEBI_83781 (R)-tebuconazole http://purl.obolibrary.org/obo/CHEBI_83779 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol The (R)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol. http://purl.obolibrary.org/obo/CHEBI_83906 (S)-diniconazole http://purl.obolibrary.org/obo/CHEBI_83909 (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol A (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol that is the (S)-enantiomer of diniconazole. http://purl.obolibrary.org/obo/CHEBI_83911 diniconazole-M http://purl.obolibrary.org/obo/CHEBI_83909 (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol A (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol that is the active R-enantiomer of diniconazole. A fungicide used to control a range of diseases including mildew, bunts and smuts. http://purl.obolibrary.org/obo/CHEBI_86482 strobilurin antifungal agent http://purl.obolibrary.org/obo/CHEBI_86478 antibiotic antifungal agent Any antibiotic antifungal agents whose structure is based on the antifungal agents originally isolated from the fungus Strobilurus tenacellus. http://purl.obolibrary.org/obo/CHEBI_8984 sodium dodecyl sulfate http://purl.obolibrary.org/obo/CHEBI_38700 organic sodium salt An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate. http://purl.obolibrary.org/obo/CHEBI_9986 vinclozolin http://purl.obolibrary.org/obo/CHEBI_60911 racemate A racemate comprising equimolar amounts of (R)- and (S)-vinclozolin. A fungicide used mainly on oilseed rape, vines, fruit and vegetables to control Botrytis, Sclerotinia and Monilia spp. http://purl.obolibrary.org/obo/PR_000014841 sonic hedgehog protein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human SHH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000015557 spondin-1 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human SPON1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000015658 SCO-spondin http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human SSPO gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000015665 somatostatin http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human SST gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000016004 tachykinin-3 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human TAC3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000016043 T-cell acute lymphocytic leukemia protein 1 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human TAL1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000017299 VIP peptides http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human VIP gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_P25918 B-lymphocyte antigen CD19 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD19 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P26952 interleukin-3 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-3 receptor class 2 alpha chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P31996 macrosialin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrosialin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P32648 VIP peptides (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A VIP peptides that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P32848 parvalbumin alpha (mouse) http://purl.obolibrary.org/obo/PR_000013502 parvalbumin alpha A parvalbumin alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q6R6I7 relaxin receptor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A relaxin receptor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9CXM0 chondrolectin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A chondrolectin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9D387 lysosome-associated membrane glycoprotein 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lysosome-associated membrane glycoprotein 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9QXH4 integrin alpha-X (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-X that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9R1R0 LIM/homeobox protein Lhx6 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A LIM/homeobox protein Lhx6 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0035819 abdominopelvic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the ventral body cavity that is within the abdominal segment of the trunk, which encompasses the abdomen proper plus pelvic cavity. http://purl.obolibrary.org/obo/CHEBI_136622 aci-nitro compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Organonitrogen compounds that have the general structure R1(R2)C=N(O)OH (R1,R2 = H, organyl). They are tautomers of C-nitro compounds. http://purl.obolibrary.org/obo/CHEBI_136651 S100 calcium-binding protein B inhibitor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any inhibitor of S100 calcium-binding protein B. http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process One of the two nuclear divisions that occur as part of the meiotic cell cycle. http://purl.obolibrary.org/obo/CHEBI_136859 pro-agent http://purl.obolibrary.org/obo/CHEBI_33232 application A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent. http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering http://purl.obolibrary.org/obo/GO_0051640 organelle localization The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. http://purl.obolibrary.org/obo/GO_0150063 visual system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. http://purl.obolibrary.org/obo/GO_0110122 myotube cell migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse. http://purl.obolibrary.org/obo/GO_0110123 regulation of myotube cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of myotube cell migration. http://purl.obolibrary.org/obo/GO_0110124 positive regulation of myotube cell migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration. http://purl.obolibrary.org/obo/GO_0110125 negative regulation of myotube cell migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration. http://purl.obolibrary.org/obo/GO_0120193 tight junction organization http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/UBERON_8440015 noradrenergic cell groups http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Collections of neurons in the central nervous system that have been demonstrated by histochemical fluorescence to contain the neurotransmitter norepinephrine (noradrenalin). http://purl.obolibrary.org/obo/CL_4023035 lateral ganglionic eminence derived neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that is derived from a precursor cell in the lateral ganglion eminence. http://purl.obolibrary.org/obo/GO_0141187 nucleic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process The biosynthetic process resulting in the formation of a nucleic acid. http://purl.obolibrary.org/obo/CL_4042017 alpha1-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte The dorsal-most tanycyte type of the third venticle. These cells projects into the ventromedial or dorsomedial nucleus of the hypothalamus. This type of tanycyte extends its protrusions close to parenchymal neurons without contacting blood vessels. It expresses the glial marker S-100β. http://purl.obolibrary.org/obo/CL_4042018 alpha2-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte Tanycyte of the third ventricle, located immediately ventral to alpha-1 tanycytes. These cells project to the ventromedial and arcuate nuclei of the hypothalamus and express the glial marker S-100β. http://purl.obolibrary.org/obo/CL_4042019 beta1-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte A type of tanycyte located in ventral part of the lateral wall of the third ventricle and in the lateral infundibular recess of the brain. This tanycyte has an elongated morphology with multiple microvilli extending into the median eminence. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH). http://purl.obolibrary.org/obo/CL_4042020 beta2-tanycyte http://purl.obolibrary.org/obo/CL_0002085 tanycyte A type of tanycyte located in the floor of third ventricle and the infindibular recess. This tanycyte has an elongated morphology with multiple microvilli extending medially and ventrally to the median eminence, contacting the pial surface and blood vessels. This type of tanycyte expresses FGF receptors 1 and 2, is in contact with GnRH neurons, and is involved in the release of gonadotropin-releasing hormone (GnRH). http://purl.obolibrary.org/obo/CL_4042023 striatal pthlh-expressing interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron expressing PTHLH and PVALB that has its soma in a striatum. This GABAergic interneuron type presents a spatial expression gradient of PVALB in the mouse striatum. http://purl.obolibrary.org/obo/CL_4052002 syncytial cell http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell A multinucleate cell formed by the fusion of multiple uninuclear cells through plasma membrane fusion. This process leads to a single large cell containing multiple nuclei within a shared cytoplasm. http://purl.obolibrary.org/obo/CL_0008060 GABA-Glut neuron http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron A neuron that releases both gamma-aminobutyric acid and glutamate as vesicular neurotransmitters. http://purl.obolibrary.org/obo/CL_4307113 ABC NN_1 Pde11a arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc47a1 (Mmus), Pde11a (Mmus). It is distinguished from other ABC NN cells by expression of Pde11a. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5293 ABC NN_1. http://purl.obolibrary.org/obo/CL_4307031 Astro-NT NN_1 Six3os1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Six3os1 (Mmus), Slc36a2 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Six3os1. These cells are located in the Striatum-like amygdalar nuclei, Olfactory areas, brain , in or close to the regions: Medial amygdalar nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5211 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4307097 COP NN_1 Cck committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Bmp4 (Mmus), Cck (Mmus), Ptger1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Bmp4, Cck, Ptger1. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5277 COP NN_1. http://purl.obolibrary.org/obo/CL_4307051 Astro-OLF NN_1 Greb1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301596 Astro-OLF NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Chrdl1 (Mmus), Ano1 (Mmus), Il33 (Mmus). It is distinguished from other Astro-OLF NN_1 cells by expression of Greb1, Il33. These cells are located in the Olfactory areas, brain , in or close to the regions: Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5231 Astro-OLF NN_1. http://purl.obolibrary.org/obo/CL_4301592 Astro-TE NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Hepacam (Mmus), E330013P04Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1162 Astro-TE NN_2. http://purl.obolibrary.org/obo/CL_4301574 CB PLI Gly-Gaba_1 Purkinje layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Hmga2 (Mmus), Afap1l2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1144 CB PLI Gly-Gaba_1. http://purl.obolibrary.org/obo/CL_4307046 Astro-TE NN_3 Zic4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Ranbp3l (Mmus), Emx2os (Mmus), Zic4 (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Zic4. These cells are located in the Lateral septal complex, Isocortex, Olfactory areas , in or close to the regions: Lateral septal nucleus, rostral (rostroventral) part . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5226 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4301596 Astro-OLF NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Prss23 (Mmus), Igfbp2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1166 Astro-OLF NN_1. http://purl.obolibrary.org/obo/CL_4307040 Astro-TE NN_1 Lncpint astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Dio2 (Mmus), Lncpint (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Lncpint. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5220 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Tmem204 (Mmus), Slc6a5 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:308 DCO Il22 Gly-Gaba. http://purl.obolibrary.org/obo/CL_0000388 tendon cell http://purl.obolibrary.org/obo/CL_1000307 fibroblast of dense regular elastic tissue An elongated fibroblast that is part of a tendon. Its cytoplasm is stretched between the collagen fibres of the tendon, and it possesses a central nucleus with a prominent nucleolus. Tendon cell has a well-developed rough endoplasmic reticulum, and it is responsible for the synthesis and turnover of tendon fibres and ground substance. http://purl.obolibrary.org/obo/PATO_0000001 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities http://purl.obolibrary.org/obo/PATO_0000025 composition http://purl.obolibrary.org/obo/PATO_0000141 structure A single physical entity inhering in an bearer by virtue of the bearer's quantities or relative ratios of subparts. http://purl.obolibrary.org/obo/PATO_0000033 concentration of http://purl.obolibrary.org/obo/PATO_0000070 amount A quality inhering in a substance by virtue of the amount of the bearer's there is mixed with another substance. http://purl.obolibrary.org/obo/PATO_0000051 morphology http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a single physical entity inhering in the bearer by virtue of the bearer's size or shape or structure. http://purl.obolibrary.org/obo/PATO_0000052 shape http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphological quality inhering in a bearer by virtue of the bearer's ratios of distances between its features (points, edges, surfaces and also holes etc). http://purl.obolibrary.org/obo/PATO_0000057 occurrence http://purl.obolibrary.org/obo/PATO_0002323 temporal distribution quality A quality of a single process inhering in a bearer by virtue of the bearer's occurrence. http://purl.obolibrary.org/obo/PATO_0000068 qualitative http://purl.obolibrary.org/obo/PATO_0000001 quality A quality of an entity that is descriptive or observational, typically not represented numerically. http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) http://purl.obolibrary.org/obo/PATO_0000068 qualitative A quality inhering in a bearer by virtue of the whether the bearer differs from normal or average. http://purl.obolibrary.org/obo/PATO_0000070 amount http://purl.obolibrary.org/obo/PATO_0103000 quantitative The number of entities of this type that are part of the whole organism. http://purl.obolibrary.org/obo/PATO_0000085 sensitivity toward http://purl.obolibrary.org/obo/PATO_0001995 organismal quality A quality inhering in a bearer by virtue of the bearer's disposition to detect or perceive external stimulation. http://purl.obolibrary.org/obo/PATO_0000117 size http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphology quality inhering in a bearer by virtue of the bearer's physical magnitude. http://purl.obolibrary.org/obo/PATO_0000136 closure http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphological quality pertaining to the degree to which an object contains an opening, aperture, orifice or vent. http://purl.obolibrary.org/obo/PATO_0000141 structure http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphology quality inhering in a bearer by virtue of the bearer's relative position, shape, arrangements and connectivity of an organism's various parts; the pattern underlying its form. http://purl.obolibrary.org/obo/PATO_0000150 texture http://purl.obolibrary.org/obo/PATO_0000051 morphology A morphologic quality inhering in a bearer by virtue of the bearer's relative size, organization and distribution of its surface elements or the representation or invention of the appearance of its surface; visual and tactile surface characteristics. http://purl.obolibrary.org/obo/PATO_0000161 rate http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process A quality of a single process inhering in a bearer by virtue of the bearer's occurrence per unit time. http://purl.obolibrary.org/obo/PATO_0000169 viability http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer or a population by virtue of the bearer's disposition to survive and develop normally or the number of surviving individuals in a given population. http://purl.obolibrary.org/obo/PATO_0000297 arrested http://purl.obolibrary.org/obo/PATO_0002324 offset quality A quality of a process which ends earlier than the natural end time or reference process. http://purl.obolibrary.org/obo/PATO_0000402 branched http://purl.obolibrary.org/obo/PATO_0002009 branchiness A branchiness quality inhering in a bearer by virtue of the bearer's having branches. http://purl.obolibrary.org/obo/PATO_0000407 flat http://purl.obolibrary.org/obo/PATO_0002254 flattened A quality inhering in a bearer by virtue of the bearer's having a horizontal surface without a slope, tilt, or curvature. http://purl.obolibrary.org/obo/PATO_0000411 circular http://purl.obolibrary.org/obo/PATO_0000947 elliptic A shape quality inhering in a bearer by virtue of the bearer's being such that every part of the surface or the circumference is equidistant from the center. http://purl.obolibrary.org/obo/PATO_0000460 abnormal http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality inhering in a bearer by virtue of the bearer's deviation from normal or average. http://purl.obolibrary.org/obo/PATO_0000461 normal http://purl.obolibrary.org/obo/PATO_0000068 qualitative A quality inhering in a bearer by virtue of the bearer's exhibiting no deviation from normal or average. http://purl.obolibrary.org/obo/PATO_0000462 absent http://purl.obolibrary.org/obo/PATO_0000070 amount A quality denoting the lack of an entity. http://purl.obolibrary.org/obo/PATO_0000467 present http://purl.obolibrary.org/obo/PATO_0000070 amount A quality inhering in a bearer by virtue of the bearer's existence. http://purl.obolibrary.org/obo/PATO_0000470 increased amount http://purl.obolibrary.org/obo/PATO_0002300 increased quality An amount which is relatively high. http://purl.obolibrary.org/obo/PATO_0000498 increased duration http://purl.obolibrary.org/obo/PATO_0002304 increased process quality A duration quality of a process which is relatively high. http://purl.obolibrary.org/obo/PATO_0000499 decreased duration http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality A duration quality of a process which is relatively low. http://purl.obolibrary.org/obo/PATO_0000502 delayed http://purl.obolibrary.org/obo/PATO_0002325 onset quality A quality of a process which starts later than the natural start time or the reference process. http://purl.obolibrary.org/obo/PATO_0000516 sensitive toward http://purl.obolibrary.org/obo/PATO_0000085 sensitivity toward A quality inhering in a bearer by virtue of the bearer's having sensitivity toward an external stimulus. http://purl.obolibrary.org/obo/PATO_0000573 increased length http://purl.obolibrary.org/obo/PATO_0000122 length A length quality which is relatively large. http://purl.obolibrary.org/obo/PATO_0000574 decreased length http://purl.obolibrary.org/obo/PATO_0000122 length A length quality which is relatively small. http://purl.obolibrary.org/obo/PATO_0000586 increased size http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A size quality which is relatively high. http://purl.obolibrary.org/obo/PATO_0000587 decreased size http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A size quality which is relatively low. http://purl.obolibrary.org/obo/PATO_0000608 closed http://purl.obolibrary.org/obo/PATO_0000136 closure A morphological quality inhering in a bearer by virtue of the bearer's affording blocked passage or view. http://purl.obolibrary.org/obo/PATO_0000694 premature http://purl.obolibrary.org/obo/PATO_0002325 onset quality A quality of a process which starts earlier than the natural start time or the reference process. http://purl.obolibrary.org/obo/PATO_0000718 lethal (sensu genetics) http://purl.obolibrary.org/obo/PATO_0000169 viability A viability quality inhering in a population by virtue of the bearer's long term survival inability. http://purl.obolibrary.org/obo/PATO_0000911 decreased rate http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality A rate which is relatively low. http://purl.obolibrary.org/obo/PATO_0000912 increased rate http://purl.obolibrary.org/obo/PATO_0002304 increased process quality A rate which is relatively high. http://purl.obolibrary.org/obo/PATO_0000947 elliptic http://purl.obolibrary.org/obo/PATO_0002318 superelliptic A spheroid quality inhering in a bearer by virtue of the bearer's being oval with two axes of symmetry, as produced by a conical section. http://purl.obolibrary.org/obo/PATO_0000957 opacity http://purl.obolibrary.org/obo/PATO_0001300 optical quality An optical quality which obtains by virtue of the ability of the bearer to absorb visible light. http://purl.obolibrary.org/obo/PATO_0000963 opaque http://purl.obolibrary.org/obo/PATO_0000957 opacity A optical quality inhering in a bearer by virtue of the bearer's not being clear; not transmitting or reflecting light or radiant energy. http://purl.obolibrary.org/obo/PATO_0000964 transparent http://purl.obolibrary.org/obo/PATO_0000957 opacity A optical quality inhering in a bearer by virtue of the bearer's lacking opacity. http://purl.obolibrary.org/obo/PATO_0001018 physical quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of a physical entity that exists through action of continuants at the physical level of organisation in relation to other entities. http://purl.obolibrary.org/obo/PATO_0001031 elasticity http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality inhering in a bearer by virtue of the bearer's disposition to recover its size and shape after deformation in any way. http://purl.obolibrary.org/obo/PATO_0001046 resistance to http://purl.obolibrary.org/obo/PATO_0001995 organismal quality A quality inhering in a bearer by virtue of the bearer's disposition to resist to a stimulus. http://purl.obolibrary.org/obo/PATO_0001159 concentrated http://purl.obolibrary.org/obo/PATO_0000033 concentration of A concentration quality inhering in a bearer by virtue of the bearer's exhibiting concentration. http://purl.obolibrary.org/obo/PATO_0001162 increased concentration http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A concentration which is higher relative to the normal or average. http://purl.obolibrary.org/obo/PATO_0001163 decreased concentration http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A concentration which is lower relative to the normal or average. http://purl.obolibrary.org/obo/PATO_0001171 elastic http://purl.obolibrary.org/obo/PATO_0001031 elasticity An elasticity quality inhering in a bearer by virtue of the bearer's ability to recover its size and shape after deformation in any way. http://purl.obolibrary.org/obo/PATO_0001178 resistant to http://purl.obolibrary.org/obo/PATO_0001046 resistance to A resistance quality inhering in a bearer by virtue of the bearer's resistance to a stimulus. http://purl.obolibrary.org/obo/PATO_0001236 process quality http://purl.obolibrary.org/obo/PATO_0000001 quality A quality which inheres in an process. http://purl.obolibrary.org/obo/PATO_0001241 physical object quality http://purl.obolibrary.org/obo/PATO_0000001 quality A quality which inheres in a continuant. http://purl.obolibrary.org/obo/PATO_0001300 optical quality http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation An EM radiation quality in which the EM radiation is within the fiat range of the spectrum visible deemed to be light. http://purl.obolibrary.org/obo/PATO_0001309 duration http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process A process quality inhering in a bearer by virtue of the bearer's magnitude of the temporal extent between the starting and ending point. http://purl.obolibrary.org/obo/PATO_0001393 euploid http://purl.obolibrary.org/obo/PATO_0001374 ploidy A ploidy quality inhering in a bearer by virtue of the bearer's containing an integral multiple of the monoploid number, possibly excluding the sex-determining chromosomes. http://purl.obolibrary.org/obo/PATO_0001397 cellular potency http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality that arises by virtue of whether the bearer's disposition to differentiate into one or more mature cell types. http://purl.obolibrary.org/obo/PATO_0001400 unipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to produce only one differentiated cell type. http://purl.obolibrary.org/obo/PATO_0001401 oligopotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to form multiple differentiated cell types of a specific lineage and lack self renewing capacity. http://purl.obolibrary.org/obo/PATO_0001402 multipotent http://purl.obolibrary.org/obo/PATO_0001397 cellular potency A cellular potency that is the capacity to form multiple differentiated cell types. http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of bearer's number of nuclei. http://purl.obolibrary.org/obo/PATO_0001405 anucleate http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality A nucleate quality inhering in a bearer by virtue of the bearer's having no nucleus. http://purl.obolibrary.org/obo/PATO_0001407 mononucleate http://purl.obolibrary.org/obo/PATO_0002505 nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having one nucleus. http://purl.obolibrary.org/obo/PATO_0001410 striated http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel. http://purl.obolibrary.org/obo/PATO_0001457 sensitivity of a process http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process A quality of a process inhering in bearer by virtue of the bearer's disposition to respond to stimulation. http://purl.obolibrary.org/obo/PATO_0001549 increased sensitivity toward http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A sensitivity toward an external stimulus which is higher than normal/average. http://purl.obolibrary.org/obo/PATO_0001550 decreased sensitivity toward http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A sensitivity toward an external stimulus which is lower than normal/average. http://purl.obolibrary.org/obo/PATO_0001551 increased sensitivity of a process http://purl.obolibrary.org/obo/PATO_0002304 increased process quality A sensitivity of a process which is higher than normal or average. http://purl.obolibrary.org/obo/PATO_0001552 decreased sensitivity of a process http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality A sensitivity of a process which is lower than normal or average. http://purl.obolibrary.org/obo/PATO_0001555 has number of http://purl.obolibrary.org/obo/PATO_0000070 amount The number of parts of a particular type that the bearer entity has. This is a relational quality, and thus holds between two entities: the bearer of the quality, and the type of parts. http://purl.obolibrary.org/obo/PATO_0001558 lacking processual parts http://purl.obolibrary.org/obo/PATO_0001564 extra or missing processual parts A quality of a process inhering in a bearer by virtue of the bearer's lacking a processual part as specified by the additional entity. http://purl.obolibrary.org/obo/PATO_0001564 extra or missing processual parts http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality of a process inhering in a bearer by virtue of the bearer's processual parts. http://purl.obolibrary.org/obo/PATO_0001579 contractility http://purl.obolibrary.org/obo/PATO_0001018 physical quality A physical quality that is the ability to contract or shrink. http://purl.obolibrary.org/obo/PATO_0001580 increased contractility http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A contractility which is relatively high. http://purl.obolibrary.org/obo/PATO_0001581 decreased contractility http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A contractility which is relatively low. http://purl.obolibrary.org/obo/PATO_0001591 curvature http://purl.obolibrary.org/obo/PATO_0000052 shape A surface shape quality inhering in a bearer by virtue of the bearer's exhibiting a degree of bending. http://purl.obolibrary.org/obo/PATO_0001650 increased resistance to http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A resistance to a stimulus which is relatively high. http://purl.obolibrary.org/obo/PATO_0001651 decreased resistance to http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A resistance to a stimulus which is relatively low. http://purl.obolibrary.org/obo/PATO_0001690 contractile http://purl.obolibrary.org/obo/PATO_0001579 contractility A contractility quality inhering in a bearer by virtue of the bearer's ability of contracting or being contracted. http://purl.obolibrary.org/obo/PATO_0001708 1-D extent http://purl.obolibrary.org/obo/PATO_0000117 size A size quality inhering in an bearer by virtue of the bearer's extension in one dimension. http://purl.obolibrary.org/obo/PATO_0001748 invaginated http://purl.obolibrary.org/obo/PATO_0001857 concave A shape quality in which a portion of the outermost boundary of an entity folds in space such that a portion that was originally convex is now concave. http://purl.obolibrary.org/obo/PATO_0001857 concave http://purl.obolibrary.org/obo/PATO_0002005 concavity A shape quality in a bearer by virtue of the bearer's curving inward. http://purl.obolibrary.org/obo/PATO_0001873 cylindrical http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a consistently-sized round cross section. http://purl.obolibrary.org/obo/PATO_0001905 has normal numbers of parts of type http://purl.obolibrary.org/obo/PATO_0001555 has number of The bearer of this quality has_part = n, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. http://purl.obolibrary.org/obo/PATO_0001908 multinucleate http://purl.obolibrary.org/obo/PATO_0002505 nucleated A nucleate quality inhering in a bearer by virtue of the bearer's having more than one nucleus. http://purl.obolibrary.org/obo/PATO_0001987 saccular http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities A structural quality inhering in a bearer by virtue of the bearer's having a three dimensional cavity with a narrow or no opening, and often containing an anatomical substance. http://purl.obolibrary.org/obo/PATO_0001992 cellularity http://purl.obolibrary.org/obo/PATO_0001995 organismal quality An organismal quality inhering in a bearer by virtue of the bearer's consisting cells. http://purl.obolibrary.org/obo/PATO_0001993 multicellular http://purl.obolibrary.org/obo/PATO_0001992 cellularity A cellularity quality inhering in a bearer by virtue of the bearer's consisting of more than one cell. http://purl.obolibrary.org/obo/PATO_0001997 decreased amount http://purl.obolibrary.org/obo/PATO_0002301 decreased quality An amount which is relatively low. http://purl.obolibrary.org/obo/PATO_0001999 lacks parts or has fewer parts of type http://purl.obolibrary.org/obo/PATO_0002083 altered number of The bearer of this quality has_part < n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. This case includes the limit case, where the bearer lacks all parts of the specified type. http://purl.obolibrary.org/obo/PATO_0002000 lacks all parts of type http://purl.obolibrary.org/obo/PATO_0001999 lacks parts or has fewer parts of type A quality of physical entities inhering in a bearer by virtue of the bearer's lacking a physical part as specified by the additional entity. http://purl.obolibrary.org/obo/PATO_0002001 has fewer parts of type http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality The bearer of this quality has_part < n AND has_part > 0 of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. Formally: If a bearer entity e has fewer parts of type X at time t, then the number of instances x of X at t such that x part_of e is < n, where n is either the normal number for comparable entities, or n is stated explicitly. http://purl.obolibrary.org/obo/PATO_0002002 has extra parts of type http://purl.obolibrary.org/obo/PATO_0002305 increased object quality The bearer of this quality has_part > n of the indicated entity type, where n is the normal amount for a comparable organism. Note that the bearer of the quality is the whole, not the part. http://purl.obolibrary.org/obo/PATO_0002005 concavity http://purl.obolibrary.org/obo/PATO_0000052 shape Surface shape that refers to the inward or outward curvature of the surface. http://purl.obolibrary.org/obo/PATO_0002006 2-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 2 dimensional entity, such as a cross section or projection of a 3 dimensional entity. http://purl.obolibrary.org/obo/PATO_0002007 convex 3-D shape http://purl.obolibrary.org/obo/PATO_0002266 3-D shape A complete three dimensional shape in which for every line connecting pair of points on the object is within the object. Or: a shape lacking cavities. Contrast: concave. http://purl.obolibrary.org/obo/PATO_0002009 branchiness http://purl.obolibrary.org/obo/PATO_0000052 shape A shape quality inhering in a bearer by virtue of the degree to which there are subdivisions or offshoots in a bearer entity. http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality that inheres in a bearer by virtue of the bearer's containing hollow areas. http://purl.obolibrary.org/obo/PATO_0002039 biconcave http://purl.obolibrary.org/obo/PATO_0001857 concave A concave quality inhering in a bearer by virtue of the bearer's curving inward on both sides or surfaces. http://purl.obolibrary.org/obo/PATO_0002045 dendritic http://purl.obolibrary.org/obo/PATO_0000402 branched A branched quality inhering in a bearer by virtue of the bearer's having smaller branches arising from larger branches. Resembling a tree in branching structure. http://purl.obolibrary.org/obo/PATO_0002050 normal amount http://purl.obolibrary.org/obo/PATO_0000467 present An amount which normal. http://purl.obolibrary.org/obo/PATO_0002051 increased occurrence http://purl.obolibrary.org/obo/PATO_0002304 increased process quality An occurrence which is relatively high. http://purl.obolibrary.org/obo/PATO_0002052 decreased occurrence http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality An occurrence which is relatively low. http://purl.obolibrary.org/obo/PATO_0002064 fenestrated http://purl.obolibrary.org/obo/PATO_0000141 structure A structure quality inhering in a bearer by virtue of the bearer's delimited by a surface with holes. http://purl.obolibrary.org/obo/PATO_0002078 hollow http://purl.obolibrary.org/obo/PATO_0002014 structure, cavities A quality inhering in a bearer by virtue of the bearer's having an empty space or cavity within. http://purl.obolibrary.org/obo/PATO_0002083 altered number of http://purl.obolibrary.org/obo/PATO_0001555 has number of Having extra or fewer parts. http://purl.obolibrary.org/obo/PATO_0002094 basophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for basic dyes under specific pH conditions. http://purl.obolibrary.org/obo/PATO_0002124 laminar http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a bearer by virtue of the bearer's processing the form of a thin plate sheet or layer. http://purl.obolibrary.org/obo/PATO_0002146 virulence http://purl.obolibrary.org/obo/PATO_0001995 organismal quality A quality inhering in a bearer by virtue of the severity of infectious disease caused by the bearer in a target organism. http://purl.obolibrary.org/obo/PATO_0002147 reduced virulence http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality A virulence that is relatively low. http://purl.obolibrary.org/obo/PATO_0002148 increased virulence http://purl.obolibrary.org/obo/PATO_0002305 increased object quality A virulence that is relatively high. http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance http://purl.obolibrary.org/obo/PATO_0001018 physical quality A quality inhering in a bearer by virtue of its constitution. http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical http://purl.obolibrary.org/obo/PATO_0001873 cylindrical A cylindrical shape quality inhering in a bearer by virtue of the bearer's being imperfectly cylindrical or approximately cylindrical. http://purl.obolibrary.org/obo/PATO_0002254 flattened http://purl.obolibrary.org/obo/PATO_0001591 curvature A quality inhering in a bearer by virtue of the bearer's surface becoming more extended in a plane. http://purl.obolibrary.org/obo/PATO_0002255 grooved http://purl.obolibrary.org/obo/PATO_0000150 texture Texture quality inhering in a bearer by virtue of the bearer's being marked with one or more channels. http://purl.obolibrary.org/obo/PATO_0002266 3-D shape http://purl.obolibrary.org/obo/PATO_0000052 shape A shape that inheres in a 3 dimensional entity. http://purl.obolibrary.org/obo/PATO_0002287 increased elasticity http://purl.obolibrary.org/obo/PATO_0002305 increased object quality An elasticity which is relatively high. http://purl.obolibrary.org/obo/PATO_0002288 decreased elasticity http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality An elasticity which is relatively low. http://purl.obolibrary.org/obo/PATO_0002299 tubular http://purl.obolibrary.org/obo/PATO_0002078 hollow A cylindrical shape that is hollow. http://purl.obolibrary.org/obo/PATO_0002300 increased quality http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002301 decreased quality http://purl.obolibrary.org/obo/PATO_0000069 deviation (from_normal) A quality that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002302 decreased process quality http://purl.obolibrary.org/obo/PATO_0002301 decreased quality A quality of a process that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002303 decreased object quality http://purl.obolibrary.org/obo/PATO_0002301 decreased quality A quality of an object that has a value that is decreased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002304 increased process quality http://purl.obolibrary.org/obo/PATO_0002300 increased quality A quality of a process that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002305 increased object quality http://purl.obolibrary.org/obo/PATO_0002300 increased quality A quality of an object that has a value that is increased compared to normal or average. http://purl.obolibrary.org/obo/PATO_0002309 fiber shaped http://purl.obolibrary.org/obo/PATO_0002226 subcylindrical A convex 3-D shape quality inhering in a bearer by virtue of the bearer's exhibiting a by virtue of the bearer's exhibiting a consistently sized and approximately round cross-section along its length, which is many times larger than its diameter. http://purl.obolibrary.org/obo/PATO_0002318 superelliptic http://purl.obolibrary.org/obo/PATO_0002006 2-D shape A shape constituting a transition between a rectangle and a circle; a closed curve, of which the circle and ellipse are special cases, whose parametric equation is x = a.cos2/rt, y = b.cos2/rt http://purl.obolibrary.org/obo/PATO_0002323 temporal distribution quality http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process A temporal distribution pattern of process occurrences within a regulation/reference process. http://purl.obolibrary.org/obo/PATO_0002324 offset quality http://purl.obolibrary.org/obo/PATO_0002323 temporal distribution quality The temporal relation between the end of the process with respect to a reference process. http://purl.obolibrary.org/obo/PATO_0002325 onset quality http://purl.obolibrary.org/obo/PATO_0002323 temporal distribution quality The temporal relation between the start of the process with respect to a reference process. http://purl.obolibrary.org/obo/PATO_0002418 acidophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for acidic dyes under specific pH conditions. http://purl.obolibrary.org/obo/PATO_0002422 acinar http://purl.obolibrary.org/obo/PATO_0000141 structure Pertaining to the individual parts making up an aggregate fruit like a many-lobed "berry," such as a raspberry. http://purl.obolibrary.org/obo/PATO_0002462 collagenous http://purl.obolibrary.org/obo/PATO_0000025 composition A composition quality inhering in an bearer by virtue of the bearer's consisting of collagen. http://purl.obolibrary.org/obo/PATO_0002478 transversely striated http://purl.obolibrary.org/obo/PATO_0001410 striated A shape quality inhering in a bearer by virtue of the bearer's being marked by narrow lines or grooves, usually parallel, that are oriented transversely relative to the long axis of the bearer. http://purl.obolibrary.org/obo/PATO_0002487 single organismal process quality http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality inhering in a process by virtue of that process having exactly one organism as a participant. http://purl.obolibrary.org/obo/PATO_0002505 nucleated http://purl.obolibrary.org/obo/PATO_0001404 nucleate quality A nucleate quality inhering in a bearer by virtue of the bearer's having one or more nucleus. http://purl.obolibrary.org/obo/PATO_0010001 disconnected http://purl.obolibrary.org/obo/PATO_0000141 structure A structural quality inhering in the bearer by virtue of the bearer consisting of multiple structures lacking any physical connection to each other. http://purl.obolibrary.org/obo/PATO_0015006 polymeric http://purl.obolibrary.org/obo/PATO_0000141 structure A quality inhering in a structure by virtue of it consisting of many of repeated, similar or identical subunits, arranged in some orderly array. http://purl.obolibrary.org/obo/UBERON_0035044 olfactory cortex layer 3 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Deepest layer of olfactory cortex. http://purl.obolibrary.org/obo/UBERON_0035403 hypophysial artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies the pituitary gland. http://purl.obolibrary.org/obo/UBERON_0035539 esophageal artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery Any of several arteries that arise from the aorta and supply blood to the esophagus. http://purl.obolibrary.org/obo/UBERON_0035815 paracardial fat http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat Fat deposits in the mediastinum outside the parietal pericardium . http://purl.obolibrary.org/obo/GO_0061938 protein localization to somatodendritic compartment http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to or maintained in a location within the somatodendritic compartment. http://purl.obolibrary.org/obo/GO_0110057 regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0110058 positive regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045603 positive regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0110059 negative regulation of blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045602 negative regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis The assembly and secretion a set of components to form an extracellular vesicule, a membrane-bounded vesicle that is released into the extracellular region. Extracellular vesicles include exosomes, microvesicles and apoptotic bodies, based on the mechanism by which they are released from cells and differentiated based on their size and content. http://purl.obolibrary.org/obo/PATO_0045000 normal rate http://purl.obolibrary.org/obo/PATO_0045073 normal process quality A rate which is relatively normal. http://purl.obolibrary.org/obo/GO_0140297 DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0008134 transcription factor binding Binding to a DNA-binding transcription factor, a protein that interacts with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype http://purl.obolibrary.org/obo/PHIPO_0000505 phenotype Any of the set of observable characteristics arising from the interaction of a potentially pathogenic organism with a host organism. http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype http://purl.obolibrary.org/obo/PHIPO_0000505 phenotype Any of the set of observable characteristics of a single organism resulting from the interaction of its genotype with the environment. http://purl.obolibrary.org/obo/PHIPO_0000003 tissue phenotype http://purl.obolibrary.org/obo/PHIPO_0000402 individual organism phenotype A single organism phenotype that is observed at the level of a tissue (eg leaf, inflorescence, ear or kidney). http://purl.obolibrary.org/obo/PHIPO_0000004 unaffected pathogenicity http://purl.obolibrary.org/obo/PHIPO_0000006 pathogenicity phenotype A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is unaffected (i.e the same as wild-type, it could be pathogenic or non-pathogenic). http://purl.obolibrary.org/obo/PHIPO_0000006 pathogenicity phenotype http://purl.obolibrary.org/obo/PHIPO_0001179 infective ability phenotype A phenotype that is relevant to pathogenicity. Pathogenicity is the ability of an organism, a pathogen, to produce an infectious disease in another organism http://purl.obolibrary.org/obo/PHIPO_0000009 gain of pathogenicity http://purl.obolibrary.org/obo/PHIPO_0000006 pathogenicity phenotype A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is obtained (pathogenicity was absent and is now present). http://purl.obolibrary.org/obo/PHIPO_0000010 loss of pathogenicity http://purl.obolibrary.org/obo/PHIPO_0000006 pathogenicity phenotype A phenotype where the ability of a pathogen, to produce an infectious disease in another organism is abolished (pathogenicity was present and is now absent). http://purl.obolibrary.org/obo/PHIPO_0000011 virulence phenotype http://purl.obolibrary.org/obo/PHIPO_0001179 infective ability phenotype A phenotype that is relevant to virulence. Virulence is the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism. (Virulence is observed where pathogenicity is present). http://purl.obolibrary.org/obo/PHIPO_0000012 unaffected virulence http://purl.obolibrary.org/obo/PHIPO_0000011 virulence phenotype A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is unchanged (i.e. the same degree of infectious disease as wild-type interaction). http://purl.obolibrary.org/obo/PHIPO_0000014 increased virulence http://purl.obolibrary.org/obo/PHIPO_0000011 virulence phenotype A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is increased (i.e. more symptoms than normal). http://purl.obolibrary.org/obo/PHIPO_0000015 reduced virulence http://purl.obolibrary.org/obo/PHIPO_0000011 virulence phenotype A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is decreased (i.e. fewer symptoms than normal). http://purl.obolibrary.org/obo/PHIPO_0000016 normal single species phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A single organism phenotype which is normal (i.e. the same as wild-type). http://purl.obolibrary.org/obo/PHIPO_0000017 abnormal single species phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A single organism phenotype which is abnormal (i.e. different than wild-type). http://purl.obolibrary.org/obo/PHIPO_0000018 lipid droplets present in decreased numbers http://purl.obolibrary.org/obo/PHIPO_0000474 abnormal number of lipid droplets A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer lipid droplets than normal. http://purl.obolibrary.org/obo/PHIPO_0000019 inviable cell http://purl.obolibrary.org/obo/PHIPO_0001222 cell viability phenotype A lethal single organism cell level phenotype resulting from altering a gene product that is essential for the life of the organism. http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical http://purl.obolibrary.org/obo/PHIPO_0001218 chemical phenotype A growth phenotype which describes the sensitivity of individuals or populations after exposure to a specific chemical. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical http://purl.obolibrary.org/obo/PHIPO_0001218 chemical phenotype A growth phenotype which describes the resistance of individuals or populations after exposure to a specific chemical. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000024 pathogen penetration across the barrier present http://purl.obolibrary.org/obo/PHIPO_0000160 pathogen penetration across barrier phenotype A single species pathogen penetration phenotype in which pathogen penetration of a given experimental substance/membrane is present. http://purl.obolibrary.org/obo/PHIPO_0000027 normal pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000160 pathogen penetration across barrier phenotype A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is normal (i.e indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000028 normal formation of pathogen penetration structure http://purl.obolibrary.org/obo/PHIPO_0000160 pathogen penetration across barrier phenotype A single species pathogen growth phenotype in which the formation of the pathogen penetration structure is normal (i.e same as wild-type) when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000030 pathogen penetration across the barrier absent http://purl.obolibrary.org/obo/PHIPO_0000160 pathogen penetration across barrier phenotype A single species pathogen penetration phenotype in which pathogen penetration of a given experimental substance/membrane is absent. http://purl.obolibrary.org/obo/PHIPO_0000031 abnormal pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000160 pathogen penetration across barrier phenotype A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is abnormal (i.e indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure http://purl.obolibrary.org/obo/PHIPO_0000160 pathogen penetration across barrier phenotype A single species pathogen growth phenotype in which the formation of the pathogen penetration structure is abnormal (i.e different than wild-type) when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype http://purl.obolibrary.org/obo/PHIPO_0000402 individual organism phenotype A single species phenotype that is observed at the level of an individual cell. http://purl.obolibrary.org/obo/PHIPO_0000035 mutualism present http://purl.obolibrary.org/obo/PHIPO_0000039 normal mutualism A pathogen host phenotype where the mutualism phenotype is normal (i.e. the same as wild-type), and the wild-type interaction exhibits mutualism. http://purl.obolibrary.org/obo/PHIPO_0000036 abnormal lipid droplet morphology http://purl.obolibrary.org/obo/PHIPO_0000478 lipid droplet phenotype A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of lipid droplets is abnormal. http://purl.obolibrary.org/obo/CL_0008028 visual system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that is capable of part of some visual perception. http://purl.obolibrary.org/obo/CL_0008031 cortical interneuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron An interneuron that has its soma located in the cerebral cortex. http://purl.obolibrary.org/obo/PHIPO_0000517 lipid droplets present in increased numbers http://purl.obolibrary.org/obo/PHIPO_0000474 abnormal number of lipid droplets A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain more lipid droplets than normal. http://purl.obolibrary.org/obo/PHIPO_0000518 lipid droplets present in normal numbers http://purl.obolibrary.org/obo/PHIPO_0000159 normal subcellular component A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain the same number of lipid droplets as normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000519 resistance to piperacillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to piperacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000520 resistance to florfenicol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to florfenicol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000521 resistance to boscalid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to boscalid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000523 resistance to sordarin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to sordarin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000524 resistance to ketoconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ketoconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000526 resistance to carbenicillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to carbenicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000527 resistance to enrofloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to enrofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000528 resistance to prochloraz http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to prochloraz. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000529 resistance to virginiamycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to virginiamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000530 resistance to triadimefon http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to triadimefon. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000531 resistance to cercosporamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cercosporamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000532 resistance to oxytetracycline http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to oxytetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000533 resistance to gramicidin D http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to gramicidin D. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000534 resistance to actinomycin D http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to actinomycin D. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000536 resistance to triclosan http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to triclosan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000537 resistance to captan http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to captan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000538 resistance to isoniazid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to isoniazid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000539 resistance to ciprofloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ciprofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000541 resistance to benznidazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to benznidazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000542 resistance to ethambutol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ethambutol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000543 resistance to teicoplanin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to teicoplanin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000544 resistance to cycloheximide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cycloheximide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000545 resistance to chlorothalonil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to chlorothalonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000546 resistance to cefotetan http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefotetan. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000548 resistance to hygromycin B http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to hygromycin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000549 resistance to triclabendazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to triclabendazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000550 resistance to ampicillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to ampicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000551 resistance to brassinin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to brassinin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000553 resistance to aztreonam http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to aztreonam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000554 resistance to nisin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nisin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000555 resistance to tetracycline http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000556 resistance to moxifloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to moxifloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000557 resistance to myriocin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to myriocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000558 resistance to benzylpenicillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to benzylpenicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000559 resistance to latrunculin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to latrunculin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000560 resistance to clindamycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to clindamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000561 resistance to tylosin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tylosin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000562 resistance to trovafloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to trovafloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000563 resistance to furazolidone http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to furazolidone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000564 resistance to mecillinam http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to mecillinam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000565 resistance to cefixime http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefixime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000566 resistance to tridemorph http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tridemorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000567 resistance to mancozeb http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to mancozeb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000569 resistance to netilmicin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to netilmicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000570 resistance to sulfanilamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to sulfanilamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000571 resistance to leptomycin B http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to leptomycin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000572 resistance to bleomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to bleomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000573 resistance to gentamycin C1 http://purl.obolibrary.org/obo/PHIPO_0000659 resistance to gentamicin A growth phenotype which describes the resistance of individuals or populations after exposure to gentamycin C1. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000574 resistance to pyrazinecarboxamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to pyrazinecarboxamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000575 resistance to micafungin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to micafungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000576 resistance to strobilurin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to strobilurin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000577 resistance to nikkomycin Z http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nikkomycin Z. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000578 resistance to nifurtimox http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nifurtimox. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000579 resistance to rotenone http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to rotenone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000580 resistance to sulfadimethoxine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to sulfadimethoxine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000581 resistance to flucytosine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to flucytosine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000582 resistance to cefuroxime http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefuroxime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000583 resistance to antimycin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to antimycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000584 resistance to brefeldin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to brefeldin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000586 resistance to anidulafungin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to anidulafungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000587 resistance to vinclozolin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to vinclozolin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000588 resistance to trimethoprim http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to trimethoprim. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000589 resistance to mupirocin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to mupirocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000590 resistance to voriconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to voriconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000591 resistance to alexidine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to alexidine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000592 resistance to fludioxonil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fludioxonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000593 resistance to oxacillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to oxacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000594 resistance to cefpodoxime proxetil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefpodoxime proxetil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000596 resistance to eflornithine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to eflornithine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000597 resistance to polymyxin B1 http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to polymyxin B1. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000598 resistance to pyrimethanil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to pyrimethanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000599 resistance to telithromycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to telithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000600 resistance to capreomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to capreomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000601 resistance to amikacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to amikacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000602 resistance to ethionamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ethionamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000603 resistance to doxycycline http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to doxycycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000604 resistance to meropenem http://purl.obolibrary.org/obo/PHIPO_0000693 resistance to carbapenems A growth phenotype which describes the resistance of individuals or populations after exposure to meropenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000605 resistance to 4-aminosalicylic acid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to 4-aminosalicylic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000606 resistance to rifampicin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to rifampicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000607 resistance to flutriafol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to flutriafol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000608 resistance to rifabutin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to rifabutin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000609 resistance to nalidixic acid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nalidixic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000610 resistance to linezolid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to linezolid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000611 resistance to fusidic acid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fusidic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000612 resistance to tunicamycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tunicamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000613 resistance to epoxyconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to epoxyconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000615 resistance to D-cycloserine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to D-cycloserine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000616 resistance to kanamycin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to kanamycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000617 resistance to verapamil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to verapamil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000618 resistance to streptomycin sulfate http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to streptomycin sulfate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000619 resistance to farnesol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to farnesol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000620 resistance to fenpropidin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fenpropidin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000621 resistance to gatifloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to gatifloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000622 resistance to erythromycin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to erythromycin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000623 resistance to bifonazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to bifonazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000624 resistance to azithromycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to azithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000625 resistance to posaconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to posaconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000626 resistance to prothionamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to prothionamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000627 resistance to copper http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to copper. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000628 resistance to resveratrol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to resveratrol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000629 resistance to colistin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to colistin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000630 resistance to oligomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to oligomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000631 resistance to cefepime http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefepime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000632 resistance to hydrogen peroxide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to hydrogen peroxide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000633 resistance to tigecycline http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tigecycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000634 resistance to tricyclazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tricyclazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000635 resistance to closantel http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to closantel. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000636 resistance to diniconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to diniconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000639 resistance to quinupristin-dalfopristin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to quinupristin-dalfopristin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000640 resistance to sparfloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to sparfloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000641 resistance to cefaclor http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefaclor. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000642 resistance to plumbagin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to plumbagin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000643 resistance to imipenem http://purl.obolibrary.org/obo/PHIPO_0000693 resistance to carbapenems A growth phenotype which describes the resistance of individuals or populations after exposure to imipenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000644 resistance to streptomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to streptomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000645 resistance to ticarcillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to ticarcillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000646 resistance to fenhexamid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fenhexamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000647 resistance to abamectin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to abamectin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000648 resistance to miltefosine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to miltefosine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000649 resistance to methicillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to methicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000650 resistance to ertapenem http://purl.obolibrary.org/obo/PHIPO_0000693 resistance to carbapenems A growth phenotype which describes the resistance of individuals or populations after exposure to ertapenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000651 resistance to neomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to neomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000652 resistance to rapamycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to rapamycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000653 resistance to fluconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fluconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000654 resistance to valinomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to valinomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000655 resistance to salicylhydroxamic acid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to salicylhydroxamic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000656 resistance to nicotinamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nicotinamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000657 resistance to sulbactam http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to sulbactam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000658 resistance to amoxicillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to amoxicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000659 resistance to gentamicin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to gentamicin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000660 resistance to ceftazidime http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ceftazidime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000661 resistance to sulfisoxazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to sulfisoxazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000662 resistance to bacitracin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to bacitracin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000663 resistance to difenoconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to difenoconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000664 resistance to spiroxamine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to spiroxamine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000665 resistance to ofloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000666 resistance to cyclosporine A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cyclosporine A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000667 resistance to cefotaxime http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefotaxime. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000668 resistance to cefoxitin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefoxitin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000669 resistance to fenarimol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fenarimol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000670 resistance to levofloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to levofloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000671 resistance to spectinomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to spectinomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000672 resistance to pentamidine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to pentamidine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000673 resistance to thiabendazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to thiabendazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000674 resistance to chlortetracycline http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to chlortetracycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000675 resistance to itraconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to itraconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000676 resistance to nitrofurantoin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nitrofurantoin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000677 resistance to ceftriaxone http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to ceftriaxone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000678 resistance to paromomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to paromomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000679 resistance to tebuconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tebuconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000681 resistance to nystatin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nystatin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000682 resistance to propiconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to propiconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000684 resistance to minocycline http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to minocycline. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000685 resistance to tobramycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tobramycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000686 resistance to caspofungin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to caspofungin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000688 resistance to amphotericin B http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to amphotericin B. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000689 resistance to chloramphenicol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to chloramphenicol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000690 resistance to novobiocin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to novobiocin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000691 resistance to emamectin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to emamectin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to penicillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000693 resistance to carbapenems http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to carbapenems. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000694 resistance to daptomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to daptomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000695 resistance to clarithromycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to clarithromycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000696 resistance to copper sulphate http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to copper sulphate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000697 resistance to fosfomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fosfomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000698 resistance to trichostatin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to trichostatin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000699 resistance to doripenem http://purl.obolibrary.org/obo/PHIPO_0000693 resistance to carbapenems A growth phenotype which describes the resistance of individuals or populations after exposure to doripenem. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000700 resistance to miconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to miconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000701 resistance to vancomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to vancomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000703 resistance to aureobasidin A http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to aureobasidin A. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000704 resistance to lincomycin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to lincomycin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000705 resistance to norfloxacin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to norfloxacin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000706 resistance to tiamulin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tiamulin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000707 resistance to hymexazol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to hymexazol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000708 resistance to cephalexin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cephalexin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000709 resistance to clofazimine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to clofazimine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000710 resistance to dicloxacillin http://purl.obolibrary.org/obo/PHIPO_0000692 resistance to penicillin A growth phenotype which describes the resistance of individuals or populations after exposure to dicloxacillin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000711 resistance to camptothecin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to camptothecin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000712 resistance to cefazolin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cefazolin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000713 sensitive to mupirocin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to mupirocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000716 sensitive to cefixime http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefixime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000717 sensitive to minocycline http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to minocycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000718 sensitive to polymyxin B1 http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to polymyxin B1. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000719 sensitive to fusidic acid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fusidic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000720 sensitive to brefeldin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to brefeldin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000721 sensitive to ethionamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ethionamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000722 sensitive to rotenone http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to rotenone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000723 sensitive to pyrazinecarboxamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrazinecarboxamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000724 sensitive to alexidine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to alexidine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000726 sensitive to chloramphenicol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to chloramphenicol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000727 sensitive to clofazimine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to clofazimine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000728 sensitive to emamectin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to emamectin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000729 sensitive to miltefosine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to miltefosine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000730 sensitive to sulfadimethoxine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfadimethoxine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000732 sensitive to doripenem http://purl.obolibrary.org/obo/PHIPO_0000819 sensitive to carbapenems A growth phenotype which describes the sensitivity of individuals or populations after exposure to doripenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000733 sensitive to cefaclor http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefaclor. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000734 sensitive to plumbagin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to plumbagin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000735 sensitive to cefotaxime http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefotaxime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000736 sensitive to benznidazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to benznidazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000737 sensitive to cyclosporine A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyclosporine A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000738 sensitive to spectinomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to spectinomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000739 sensitive to latrunculin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to latrunculin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000740 sensitive to oxacillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000741 sensitive to difenoconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to difenoconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000742 sensitive to triclosan http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to triclosan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000743 sensitive to tridemorph http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tridemorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000744 sensitive to virginiamycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to virginiamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000745 sensitive to neomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to neomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000746 sensitive to voriconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to voriconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000747 sensitive to brassinin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to brassinin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000748 sensitive to daptomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to daptomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000749 sensitive to bleomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to bleomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000750 sensitive to aztreonam http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to aztreonam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000751 sensitive to fludioxonil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fludioxonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000753 sensitive to ceftriaxone http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ceftriaxone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000754 sensitive to leptomycin B http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to leptomycin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000755 sensitive to amikacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to amikacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000756 sensitive to resveratrol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to resveratrol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000757 sensitive to fenhexamid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenhexamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000758 sensitive to cefpodoxime proxetil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefpodoxime proxetil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000759 sensitive to myriocin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to myriocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000760 sensitive to gentamicin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to gentamicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000761 sensitive to valinomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to valinomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000762 sensitive to tigecycline http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tigecycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000763 sensitive to moxifloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to moxifloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000764 sensitive to kanamycin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to kanamycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000765 sensitive to methicillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to methicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000766 sensitive to pentamidine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to pentamidine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000767 sensitive to gentamycin C1 http://purl.obolibrary.org/obo/PHIPO_0000760 sensitive to gentamicin A growth phenotype which describes the sensitivity of individuals or populations after exposure to gentamycin C1. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000768 sensitive to thiabendazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiabendazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000769 sensitive to gatifloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to gatifloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000770 sensitive to mecillinam http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to mecillinam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000771 sensitive to ampicillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to ampicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000772 sensitive to cefotetan http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefotetan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000773 sensitive to nystatin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to nystatin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000774 sensitive to vinclozolin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to vinclozolin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000775 sensitive to flucytosine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to flucytosine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000776 sensitive to trichostatin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to trichostatin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000777 sensitive to oxytetracycline http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxytetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000778 sensitive to eflornithine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to eflornithine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000779 sensitive to streptomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to streptomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000780 sensitive to epoxyconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to epoxyconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000781 sensitive to trimethoprim http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to trimethoprim. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000782 sensitive to nifurtimox http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to nifurtimox. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000783 sensitive to clarithromycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to clarithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000784 sensitive to nisin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to nisin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000785 sensitive to sulfanilamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfanilamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000786 sensitive to oligomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to oligomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000788 sensitive to fosfomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fosfomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000789 sensitive to telithromycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to telithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000791 sensitive to nitrofurantoin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to nitrofurantoin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000792 sensitive to linezolid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to linezolid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000793 sensitive to anidulafungin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to anidulafungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000795 sensitive to carbenicillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbenicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000796 sensitive to tunicamycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tunicamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000797 sensitive to caspofungin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to caspofungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000798 sensitive to fenarimol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenarimol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000799 sensitive to ciprofloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ciprofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000800 sensitive to farnesol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to farnesol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000801 sensitive to amphotericin B http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to amphotericin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000802 sensitive to vancomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to vancomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000803 sensitive to ketoconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ketoconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000804 sensitive to strobilurin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to strobilurin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000805 sensitive to colistin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to colistin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000806 sensitive to trovafloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to trovafloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000807 sensitive to triclabendazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to triclabendazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000808 sensitive to pyrimethanil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrimethanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000809 sensitive to florfenicol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to florfenicol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000810 sensitive to flutriafol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to flutriafol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000811 sensitive to teicoplanin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to teicoplanin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000812 sensitive to norfloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to norfloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000814 sensitive to closantel http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to closantel. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to penicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000816 sensitive to prothionamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to prothionamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000817 sensitive to isoniazid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to isoniazid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000818 sensitive to salicylhydroxamic acid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to salicylhydroxamic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000819 sensitive to carbapenems http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbapenems. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000820 sensitive to abamectin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to abamectin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000822 sensitive to antimycin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to antimycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000823 sensitive to cercosporamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cercosporamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000824 sensitive to tiamulin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tiamulin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000825 sensitive to tebuconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tebuconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000826 sensitive to ticarcillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to ticarcillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000827 sensitive to nicotinamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to nicotinamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000828 sensitive to tricyclazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tricyclazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000829 sensitive to paromomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to paromomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000830 sensitive to ofloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000831 sensitive to triadimefon http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to triadimefon. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000832 sensitive to copper sulphate http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to copper sulphate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000833 sensitive to imipenem http://purl.obolibrary.org/obo/PHIPO_0000819 sensitive to carbapenems A growth phenotype which describes the sensitivity of individuals or populations after exposure to imipenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000834 sensitive to quinupristin-dalfopristin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to quinupristin-dalfopristin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000835 sensitive to aureobasidin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to aureobasidin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000836 sensitive to rifampicin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to rifampicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000837 sensitive to rifabutin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to rifabutin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000838 sensitive to diniconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to diniconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000839 sensitive to actinomycin D http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to actinomycin D. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000840 sensitive to dicloxacillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to dicloxacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000841 sensitive to cefuroxime http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefuroxime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000842 sensitive to piperacillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to piperacillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000843 sensitive to bacitracin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to bacitracin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000844 sensitive to propiconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to propiconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000845 sensitive to meropenem http://purl.obolibrary.org/obo/PHIPO_0000819 sensitive to carbapenems A growth phenotype which describes the sensitivity of individuals or populations after exposure to meropenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000846 sensitive to chlorothalonil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to chlorothalonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000847 sensitive to posaconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to posaconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000848 sensitive to cephalexin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cephalexin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000850 sensitive to 4-aminosalicylic acid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to 4-aminosalicylic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000851 sensitive to captan http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to captan. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000853 sensitive to capreomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to capreomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000854 sensitive to gramicidin D http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to gramicidin D. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000855 sensitive to doxycycline http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to doxycycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000858 sensitive to bifonazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to bifonazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000859 sensitive to micafungin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to micafungin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000860 sensitive to ertapenem http://purl.obolibrary.org/obo/PHIPO_0000819 sensitive to carbapenems A growth phenotype which describes the sensitivity of individuals or populations after exposure to ertapenem. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000861 sensitive to cycloheximide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cycloheximide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000862 sensitive to ceftazidime http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ceftazidime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000863 sensitive to camptothecin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to camptothecin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000864 sensitive to netilmicin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to netilmicin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000865 sensitive to benzylpenicillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to benzylpenicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000866 sensitive to hymexazol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to hymexazol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000867 sensitive to streptomycin sulfate http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to streptomycin sulfate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000868 sensitive to chlortetracycline http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to chlortetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000869 sensitive to D-cycloserine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to D-cycloserine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000870 sensitive to miconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to miconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000871 sensitive to erythromycin A http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to erythromycin A. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000872 sensitive to copper http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to copper. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000873 sensitive to rapamycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to rapamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000874 sensitive to tobramycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tobramycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000875 sensitive to verapamil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to verapamil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000876 sensitive to furazolidone http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to furazolidone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000877 sensitive to cefoxitin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefoxitin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000878 sensitive to fenpropidin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpropidin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000879 sensitive to itraconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to itraconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000880 sensitive to sulfisoxazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulfisoxazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000881 sensitive to lincomycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to lincomycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000882 sensitive to tetracycline http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tetracycline. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000883 sensitive to levofloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to levofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000884 sensitive to cefazolin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefazolin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000885 sensitive to novobiocin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to novobiocin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000886 sensitive to amoxicillin http://purl.obolibrary.org/obo/PHIPO_0000815 sensitive to penicillin A growth phenotype which describes the sensitivity of individuals or populations after exposure to amoxicillin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000887 sensitive to ethambutol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ethambutol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000888 sensitive to tylosin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tylosin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000889 sensitive to clindamycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to clindamycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000890 sensitive to fluconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000891 sensitive to hygromycin B http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to hygromycin B. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000892 sensitive to boscalid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to boscalid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000893 sensitive to cefepime http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cefepime. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000894 sensitive to prochloraz http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to prochloraz. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000895 sensitive to mancozeb http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to mancozeb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000896 sensitive to spiroxamine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to spiroxamine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000897 sensitive to enrofloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to enrofloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000898 sensitive to nalidixic acid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to nalidixic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000899 sensitive to sordarin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to sordarin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000901 sensitive to azithromycin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to azithromycin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000902 sensitive to sparfloxacin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to sparfloxacin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000903 sensitive to nikkomycin Z http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to nikkomycin Z. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000904 sensitive to sulbactam http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to sulbactam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000924 host defense-induced oxidative burst level phenotype http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, which affects a pathogen induced host oxidative burst level (GO:0002679). http://purl.obolibrary.org/obo/PHIPO_0000925 abnormal cell wall organization or biogenesis http://purl.obolibrary.org/obo/PHIPO_0000931 cell wall organization or biogenesis phenotype A cellular process phenotype in which the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000927 host defense-induced reactive oxygen species present http://purl.obolibrary.org/obo/PHIPO_0000924 host defense-induced oxidative burst level phenotype A pathogen host interaction phenotype, in which the level of host reactive oxygen species (ROS) often associated with an oxidative burst response during infection is present. http://purl.obolibrary.org/obo/PHIPO_0000928 host defense-induced reactive oxygen species absent http://purl.obolibrary.org/obo/PHIPO_0000924 host defense-induced oxidative burst level phenotype A pathogen host interaction phenotype, in which the level of host reactive oxygen species (ROS) often associated with an oxidative burst response during infection is absent or at a level too low to detect. http://purl.obolibrary.org/obo/PHIPO_0000929 abnormal cellular process http://purl.obolibrary.org/obo/PHIPO_0000930 cellular process phenotype A phenotype in which a specific cellular process is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000930 cellular process phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A phenotype that affects a cellular process. http://purl.obolibrary.org/obo/PHIPO_0000931 cell wall organization or biogenesis phenotype http://purl.obolibrary.org/obo/PHIPO_0000930 cellular process phenotype A phenotype that affects cell wall organization or biogenesis. http://purl.obolibrary.org/obo/PHIPO_0000932 normal cellular process http://purl.obolibrary.org/obo/PHIPO_0000930 cellular process phenotype A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000934 abnormal nucleus http://purl.obolibrary.org/obo/PHIPO_0000415 abnormal subcellular component A single organism phenotype in which the amount, distribution, or morphology of all or part of the nucleus is abnormal. http://purl.obolibrary.org/obo/GO_0140352 export from cell http://purl.obolibrary.org/obo/GO_0009987 cellular process The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. http://purl.obolibrary.org/obo/PHIPO_0001096 resistance to stress http://purl.obolibrary.org/obo/PHIPO_0001217 stress phenotype A growth phenotype which describes the resistance of individuals or populations after exposure to a specific stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). http://purl.obolibrary.org/obo/PHIPO_0001097 resistance to cell wall stress http://purl.obolibrary.org/obo/PHIPO_0001096 resistance to stress A growth phenotype which describes the resistance of individuals or populations after exposure to a cell wall stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress http://purl.obolibrary.org/obo/PHIPO_0001217 stress phenotype A growth phenotype which describes the sensitivity of individuals or populations after exposure to a specific stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. http://purl.obolibrary.org/obo/PHIPO_0001100 increased level of pathogen RNA within host http://purl.obolibrary.org/obo/PHIPO_0001267 level of pathogen produced RNA within host phenotype A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001101 absence of pathogen asexual sporulation structures within host http://purl.obolibrary.org/obo/PHIPO_0000469 abnormal pathogen asexual sporulation within host A pathogen reproductive phenotype within host where the pathogen asexual sporulation structures are absent. http://purl.obolibrary.org/obo/PHIPO_0001102 presence of pathogen asexual sporulation structures within host lesion http://purl.obolibrary.org/obo/PHIPO_0000472 normal pathogen asexual sporulation within host A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001104 increased level of host defense-induced RNA http://purl.obolibrary.org/obo/PHIPO_0001263 host defense-induced RNA level phenotype A pathogen host interaction phenotype, in which the level of host RNA usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001105 gliotoxin absent from cell http://purl.obolibrary.org/obo/PHIPO_0001034 substance absent from cell A single species cell phenotype in which the amount of gliotoxin measured in a cell is too low to detect. http://purl.obolibrary.org/obo/PHIPO_0001106 presence of pathogen host protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000131 pathogen host protein-protein interaction phenotype A molecular function phenotype in which the binding of one pathogen protein to one host protein is present. http://purl.obolibrary.org/obo/PHIPO_0001107 absence of pathogen host protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000131 pathogen host protein-protein interaction phenotype A molecular function phenotype in which the binding of one pathogen protein to one host protein is absent. http://purl.obolibrary.org/obo/PHIPO_0001108 pathogen host interaction pH phenotype http://purl.obolibrary.org/obo/PHIPO_0000510 pathogen host interaction cell phenotype A pathogen host interaction phenotype that affects the pH in a pathogen or host cell or cellular component. http://purl.obolibrary.org/obo/PHIPO_0001113 host defense induced acidification in phagolysome present http://purl.obolibrary.org/obo/PHIPO_0001108 pathogen host interaction pH phenotype A pathogen host interaction phenotype where the host induces a pH decrease within the host phagolysome in response to pathogen colonization. http://purl.obolibrary.org/obo/PHIPO_0001114 decreased number of pathogen asexual sporulation structures within host lesion http://purl.obolibrary.org/obo/PHIPO_0000469 abnormal pathogen asexual sporulation within host A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is fewer than normal. http://purl.obolibrary.org/obo/PHIPO_0001115 decreased phosphopantetheinyl transferase activity http://purl.obolibrary.org/obo/PHIPO_0000436 decreased catalytic activity A single species molecular function phenotype in which the observed rate of phosphopantetheinyl transferase activity is decreased. http://purl.obolibrary.org/obo/PHIPO_0001116 host immune system signaling pathway pathogen-host interaction phenotype http://purl.obolibrary.org/obo/PHIPO_0001167 pathogen modulation of host immune system process phenotype A pathogen host interaction phenotype that affects a host immune system signaling pathway during pathogen infection. http://purl.obolibrary.org/obo/PHIPO_0001117 host immune signaling pathway activated by pathogen http://purl.obolibrary.org/obo/PHIPO_0001116 host immune system signaling pathway pathogen-host interaction phenotype A pathogen host interaction phenotype, in which the host immune signaling pathway is induced by a pathogen. http://purl.obolibrary.org/obo/PHIPO_0001118 abnormal protein modification http://purl.obolibrary.org/obo/PHIPO_0000929 abnormal cellular process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. http://purl.obolibrary.org/obo/PHIPO_0001119 abnormal protein phosphorylation http://purl.obolibrary.org/obo/PHIPO_0001118 abnormal protein modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001120 decreased protein phosphorylation http://purl.obolibrary.org/obo/PHIPO_0001119 abnormal protein phosphorylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. http://purl.obolibrary.org/obo/PHIPO_0001121 abnormal sexual reproductive structure development http://purl.obolibrary.org/obo/PHIPO_0000043 abnormal reproduction phenotype A single species phenotype where the sexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abnormal (GO:0048608). http://purl.obolibrary.org/obo/PHIPO_0001122 decreased number of sexual sporulation structures http://purl.obolibrary.org/obo/PHIPO_0001121 abnormal sexual reproductive structure development A single species reproductive phenotype in which the frequency of occurrence of sexual sporulation structures is fewer than normal. http://purl.obolibrary.org/obo/PHIPO_0001123 viable population http://purl.obolibrary.org/obo/PHIPO_0000514 population viability phenotype An organism population phenotype in which some organisms in the population are viable. http://purl.obolibrary.org/obo/PHIPO_0001124 decreased growth on erucic acid carbon source http://purl.obolibrary.org/obo/PHIPO_0001216 nutrient phenotype A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing erucic acid as the carbon source. http://purl.obolibrary.org/obo/PHIPO_0001125 decreased growth on oleic acid carbon source http://purl.obolibrary.org/obo/PHIPO_0001216 nutrient phenotype A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing oleic acid as the carbon source. http://purl.obolibrary.org/obo/PHIPO_0001126 decreased growth on palmitic acid carbon source http://purl.obolibrary.org/obo/PHIPO_0001216 nutrient phenotype A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing palmitic acid as the carbon source. http://purl.obolibrary.org/obo/PHIPO_0001127 decreased growth on myristic acid carbon source http://purl.obolibrary.org/obo/PHIPO_0001216 nutrient phenotype A growth phenotype which describes the decrease in growth of individuals or populations relative to normal in a medium containing myristic acid as the carbon source. http://purl.obolibrary.org/obo/PHIPO_0001128 effector-mediated suppression of host PAMP-triggered immunity present http://purl.obolibrary.org/obo/PHIPO_0001176 effector-mediated immune suppression phenotype A cell signaling pathway phenotype where the molecular pattern-induced host innate immune response signaling pathway is suppressed by a pathogen. (GO:0052034) http://purl.obolibrary.org/obo/PHIPO_0001130 stunted host growth during pathogen colonization http://purl.obolibrary.org/obo/PHIPO_0001006 abnormal host morphology during pathogen invasion A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in a decreased size of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001131 increased number of host side shoots during pathogen colonization http://purl.obolibrary.org/obo/PHIPO_0001006 abnormal host morphology during pathogen invasion A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in an increased number of side shoots produced by the host organism. http://purl.obolibrary.org/obo/PHIPO_0001132 increased size of pathogen vacuoles during host colonization http://purl.obolibrary.org/obo/PHIPO_0000999 abnormal pathogen morphology during colonization of host A pathogen host interaction phenotype where the size of the pathogen vacuoles are larger than normal during host colonization. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001133 increased cellular melanin accumulation http://purl.obolibrary.org/obo/PHIPO_0000287 increased cellular pigment accumulation A single species individual organism phenotype where the accumulation of melanin in a cell is increased. http://purl.obolibrary.org/obo/PHIPO_0001134 sensitive to potassium chloride http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to potassium chloride. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001135 sensitive to sorbitol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to sorbitol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001136 abolished development of asexual reproductive structure http://purl.obolibrary.org/obo/PHIPO_0000121 abnormal asexual reproductive structure development A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abolished (it was present and is now absent) (GO:0048608). http://purl.obolibrary.org/obo/PHIPO_0001137 increased number of hyphal septa http://purl.obolibrary.org/obo/PHIPO_0000415 abnormal subcellular component An individual organism cellular process phenotype in which the number of septa produced during hyphae formation is increased. http://purl.obolibrary.org/obo/PHIPO_0001138 decreased number of asexual reproductive structures http://purl.obolibrary.org/obo/PHIPO_0000121 abnormal asexual reproductive structure development A single species phenotype where the frequency of occurrence of asexual reproductive structures is decreased. http://purl.obolibrary.org/obo/PHIPO_0001139 decreased number of septa in asexual spore http://purl.obolibrary.org/obo/PHIPO_0000127 abnormal asexual spore morphology A single species phenotype where the frequency of occurrence of septum within an asexual spore is decreased. http://purl.obolibrary.org/obo/PR_000050216 receptor-type tyrosine-protein phosphatase C isoform CD45R http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C A receptor-type tyrosine-protein phosphatase C that is a translation product of a transcript that minimally includes the region encoded by the variable exon 4(A). http://purl.obolibrary.org/obo/PHIPO_0001198 outcome of interaction phenotype http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype that affects the disease outcome of a pathogen host interaction. http://purl.obolibrary.org/obo/PHIPO_0001199 disease absent http://purl.obolibrary.org/obo/PHIPO_0001198 outcome of interaction phenotype A pathogen host interaction phenotype where disease is absent. http://purl.obolibrary.org/obo/PHIPO_0001200 disease present http://purl.obolibrary.org/obo/PHIPO_0001198 outcome of interaction phenotype A pathogen host interaction phenotype where disease is present. http://purl.obolibrary.org/obo/CHEBI_176839 vitamin B3 http://purl.obolibrary.org/obo/CHEBI_75769 B vitamin Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms). http://purl.obolibrary.org/obo/CHEBI_184376 streptidine(2+) http://purl.obolibrary.org/obo/CHEBI_60251 guanidinium ion A guanidinium ion obtained by protonation of both guanidino groups of streptidine; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_192484 ciprofloxacin zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion A zwitterion formed from ciprofloxacin by transfer of a proton from the carboxy to the amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_192486 ciprofloxacin(1+) http://purl.obolibrary.org/obo/CHEBI_137419 secondary ammonium ion A secondary ammonium ion that is the conjugate acid of ciprofloxacin resulting from the protonation of the NH group; major species at acidic pH. http://purl.obolibrary.org/obo/CHEBI_46577 dextrofloxacin http://purl.obolibrary.org/obo/CHEBI_194135 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid The (R)-enantiomer of ofloxacin. http://purl.obolibrary.org/obo/PHIPO_0001439 increased number of septa in asexual spore http://purl.obolibrary.org/obo/PHIPO_0000127 abnormal asexual spore morphology A single species phenotype where the frequency of occurrence of septum within an asexual spore is increased. http://purl.obolibrary.org/obo/PHIPO_0001440 increased number of nuclei in asexual spore http://purl.obolibrary.org/obo/PHIPO_0000127 abnormal asexual spore morphology A single species phenotype where the frequency of occurrence of nuclei within an asexual spore is increased. http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell An epithelial cell that is specialised for the synthesis and secretion of specific biomolecules. http://purl.obolibrary.org/obo/CL_4033093 limbal epithelial stem cell of cornea http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell A stem cell that is part of the corneo-scleral limbus. This cell type resides at the basal layer of the epithelium and has a small size and high nuclear to cytoplasmatic ratio (Secker and Daniels, 2009). A limbal stem cell is responsible for corneal epithelial renewal and repair (Li et al., 2023), and to help maintain a clear corneal surface by preventing conjunctival epithelial cells from migrating onto the cornea (Wang et al., 2023). http://purl.obolibrary.org/obo/CL_4042035 molecular layer interneuron http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron A type of cerebellar inhibitory GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell type inhibits Purkinje cells and other molecular layer interneurons. This interneuron plays a crucial role in regulating cerebellar output through feedforward inhibition and is characterized by its fast-spiking properties. http://purl.obolibrary.org/obo/CL_4042039 caudal ganglionic eminence derived neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the central nervous system that develops from a caudal ganglionic eminence. http://purl.obolibrary.org/obo/CL_4042040 glutamatergic neuron of the basal ganglia http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A glutametergic neuron with its soma located in a basal ganglia. This neuron type is involved in motor control, decision making and learning. http://purl.obolibrary.org/obo/CL_4052015 endocrine gland capillary endothelial cell http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell Any capillary endothelial cell that is part of an endocrine gland. http://purl.obolibrary.org/obo/CL_4052016 pituitary gland capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell A capillary endothelial cell that is part of the pituitary gland. This cell is characterized by its fenestrated structure which facilitates the efficient transport of hormones and other signaling molecules, essential for endocrine signalling. http://purl.obolibrary.org/obo/CL_4052017 choroid plexus capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell A capillary endothelial cell that is part of the choroid plexus, characterized by its fenestrated nature with 60 to 80 nm fenestrations and lack of tight junctions. This fenestrated structure allows for the rapid delivery of water and other components, aiding in the production of cerebrospinal fluid (CSF). http://purl.obolibrary.org/obo/CL_4052030 adventitial fibroblast http://purl.obolibrary.org/obo/CL_0002503 adventitial cell A fibroblast of the adventitia of a blood vessel. This cell contributes to vascular homeostasis, remodeling, and inflammation by producing extracellular matrix components, cytokines, and growth factors. Adventitial fibroblast can transition into an activated state during injury or disease, marked by increased proliferation, migration, matrix deposition, and contractile protein expression http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The head is the anterior-most division of the body [GO]. http://purl.obolibrary.org/obo/UBERON_0000304 tendon sheath http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of membrane around a tendon. It has 2 layers: synovial sheath + fibrous tendon sheath. http://purl.obolibrary.org/obo/UBERON_0000391 leptomeninx http://purl.obolibrary.org/obo/UBERON_0002360 meninx Pia mater or arachnoid mater. http://purl.obolibrary.org/obo/UBERON_0000474 female reproductive system http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system The organs and associated structures associated with bearing offspring in a female animal. http://purl.obolibrary.org/obo/UBERON_0000915 thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Subdivision of trunk that lies between the head and the abdomen. http://purl.obolibrary.org/obo/UBERON_0000947 aorta http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart The main trunk of the systemic arterial system that carries blood from the heart to all the organs and other structures of the body, bringing oxygenated blood to all parts of the body in the systemic circulation. http://purl.obolibrary.org/obo/UBERON_0000974 neck http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that extends from the head to the pectoral girdle, encompassing the cervical vertebral column. http://purl.obolibrary.org/obo/UBERON_0000991 gonad http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ Reproductive organ that produces and releases eggs (ovary) or sperm (testis). http://purl.obolibrary.org/obo/UBERON_0001003 skin epidermis http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outer epithelial layer of the skin that is superficial to the dermis. http://purl.obolibrary.org/obo/UBERON_0001007 digestive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs devoted to the ingestion, digestion, and assimilation of food and the discharge of residual wastes. http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue which is unstriated, composed primarily of smooth muscle fibers surrounded by a reticulum of collagen and elastic fibers. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length[GO]. http://purl.obolibrary.org/obo/UBERON_0001456 face http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head A subdivision of the head that has as parts the layers deep to the surface of the anterior surface, including the mouth, eyes, and nose (when present). In vertebrates, this includes the facial skeleton and structures superficial to the facial skeleton (cheeks, mouth, eyeballs, skin of face, etc). http://purl.obolibrary.org/obo/UBERON_0001585 anterior vena cava http://purl.obolibrary.org/obo/UBERON_0004087 vena cava A vein that carries deoxygenated blood from the upper half of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0001638 vein http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel Any of the tubular branching vessels that carry blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/UBERON_0001645 trigeminal nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve that has three branches - the ophthalmic (supplying the skin of the nose and upper jaw), the maxillary and the mandibular (supplying the lower jaw). http://purl.obolibrary.org/obo/UBERON_0001649 glossopharyngeal nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve that branches into the ramus communicans (to the skin), the pretrematic (to the walls of the pharynx and mouth, viscero-sensory fibers), and the larval post-trematic branch (lost in the adult). http://purl.obolibrary.org/obo/UBERON_0001768 uvea http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The pigmented middle of the three concentric layers that make up an eye, consisting of the iris, ciliary body and choroid[WP,edited]. http://purl.obolibrary.org/obo/UBERON_0001769 iris http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The adjustable membrane, composed of the stroma and pigmented epithelium, located just in front of the crystalline lens within the eye. http://purl.obolibrary.org/obo/UBERON_0001775 ciliary body http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The thickened portion of the vascular tunic, which lies between the choroid and the iris, composed of ciliary muscle and ciliary processes. http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle Cranial nerves are nerves that emerge directly from the brain, in contrast to spinal nerves, which emerge from segments of the spinal cord. http://purl.obolibrary.org/obo/UBERON_0001835 lower lip http://purl.obolibrary.org/obo/UBERON_0001833 lip Lip that covers the lower portion of the mouth.[TAO]. http://purl.obolibrary.org/obo/UBERON_0001869 cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of two bilateral, largely symmetrical organ subdivisions within the telencephalon which contain the cerebral cortex and cerebral white matter.[FMA]. http://purl.obolibrary.org/obo/UBERON_0001886 choroid plexus http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system A network formed by blood vessels and the tela choroidea which secretes CSF into the ventricular spaces. http://purl.obolibrary.org/obo/UBERON_0001893 telencephalon http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Part of the forebrain consisting of paired olfactory bulbs and cerebral hemispheres. http://purl.obolibrary.org/obo/UBERON_0001894 diencephalon http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The division of the forebrain that develops from the foremost primary cerebral vesicle. http://purl.obolibrary.org/obo/UBERON_0001905 pineal body http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ A midline, cone like structure located in the dorso-caudal roof of the 3rd ventricle, attached by peduncles to the habenular and posterior commissures. The stalk contains nerve fibers, blood vessels, connective tissue and parenchymal cells (Paxinos, The Rat Central Nervous System, 2nd ed, pg 399). http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart Pulmonary veins are blood vessels that transport blood from the lungs to the heart[GO]. http://purl.obolibrary.org/obo/UBERON_0002019 accessory XI nerve http://purl.obolibrary.org/obo/UBERON_0035642 laryngeal nerve A cranial nerve that originates from neurons in the medulla and in the cervical spinal cord. http://purl.obolibrary.org/obo/UBERON_0002037 cerebellum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Part of the metencephalon that lies in the posterior cranial fossa behind the brain stem. It is concerned with the coordination of movement[MESH]. A large dorsally projecting part of the brain concerned especially with the coordination of muscles and the maintenance of bodily equilibrium, situated between the brain stem and the back of the cerebrum , and formed in humans of two lateral lobes and a median lobe[BTO]. Brain structure derived from the anterior hindbrain, and perhaps including posterior midbrain. The cerebellum plays a role in somatic motor function, the control of muscle tone, and balance[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002067 dermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. http://purl.obolibrary.org/obo/UBERON_0002198 neurohypophysis http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ The posterior part of the pituitary gland that secretes hormones involved in blood pressure regulation such as oxytocin and antidiuretic hormon. http://purl.obolibrary.org/obo/UBERON_0002285 telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle A brain ventricle that is part of a telencephalon. In mammals and species with an evaginated telencephalon, this is one of a pair of lateral structures, one in each hemisphere. http://purl.obolibrary.org/obo/UBERON_0002286 third ventricle http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle Part of the ventricular system of the brain, forming a single large cavity in the midline of the diencephalon; it is continuous with the lateral ventricles through the interventricular foramen and the fourth ventricle through the cerebral aqueduct. (Maryann Martone). http://purl.obolibrary.org/obo/UBERON_0002348 epicardium http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure A region of the serous membrane that forms the innermost layer of the pericardium and the outer surface of the heart. http://purl.obolibrary.org/obo/UBERON_0002349 myocardium http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue The middle layer of the heart, comprised mainly of striated cardiac muscle fibers. http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow http://purl.obolibrary.org/obo/UBERON_0000479 tissue The soft tissue that fills the cavities of bones. http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Muscle tissue is a contractile tissue made up of actin and myosin fibers[GO]. http://purl.obolibrary.org/obo/UBERON_0002390 hematopoietic system http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Anatomical system that is involved in the production of hematopoietic cells. http://purl.obolibrary.org/obo/UBERON_0002420 basal ganglion http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis An individual member of a collection of basal ganglia. Basal ganglia are subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum[NIF,modified]. http://purl.obolibrary.org/obo/UBERON_0003129 skull http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Anatomical structure that is part of the head consisting entirely of cranium and mandible[WP]. http://purl.obolibrary.org/obo/UBERON_0003292 meninx of spinal cord http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element A meninx that is part of a spinal cord [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003687 foramen magnum http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull In anatomy, in the occipital bone, the foramen magnum is one of the several oval or circular apertures in the base of the skull, through which the medulla oblongata (an extension of the spinal cord) enters and exits the skull vault. Apart from the transmission of the medulla oblongata and its membranes, the foramen magnum transmits the Spinal Accessory nerve, vertebral arteries, the anterior and posterior spinal arteries, the membrana tectoria and alar ligaments. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system One of the system of communicating cavities in the brain that are continuous with the central canal of the spinal cord, that like it are derived from the medullary canal of the embryo, that are lined with an epithelial ependyma, and that contain a serous fluid. http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest One of a series of paired embryological vascular structures formed within a pharyngeal arch; in the adult, some of these vessels give rise to the great vessels[MP]. http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of: the common carotid artery, or its branches, the external and internal carotid arteries. http://purl.obolibrary.org/obo/UBERON_0005456 jugular foramen http://purl.obolibrary.org/obo/UBERON_0018321 foramen for glossopharyngeal nerve The jugular foramen is a large aperture in the base of the skull. It is located behind the carotid canal and is formed in front by the petrous portion of the temporal, and behind by the occipital; it is generally larger on the right than on the left side. http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A thin, loose vascular connective tissue that makes up the membranes surrounding joints and the sheaths protecting tendons (particularly flexor tendons in the hands and feet) where they pass over bony prominences. Synovial tissue contains synovial cells, which secrete a viscous liquid called synovial fluid; this liquid contains protein and hyaluronic acid and serves as a lubricant and nutrient for the joint cartilage surfaces[BTO]. Synovial tissue can be found in tendons (tissues that connect muscle to bone), bursae (fluid-filled, cushioning sacs found in spaces between tendons, ligaments, and bones), and the cavity (hollow enclosed area) that separates the bones of a freely movable joint, such as the knee or elbow[BTO]. http://purl.obolibrary.org/obo/UBERON_0007798 vascular system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of all blood and lymph vessels. http://purl.obolibrary.org/obo/UBERON_0010743 meningeal cluster http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection The collection of all meningeal layers that line a central nervous system. http://purl.obolibrary.org/obo/UBERON_0016490 auditory system http://purl.obolibrary.org/obo/UBERON_0007037 mechanosensory system Is the sensory system for the sense of hearing. http://purl.obolibrary.org/obo/BFO_0000002 continuant http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. http://purl.obolibrary.org/obo/BFO_0000003 occurrent http://purl.obolibrary.org/obo/BFO_0000001 entity An entity that has temporal parts and that happens, unfolds or develops through time. http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything. http://purl.obolibrary.org/obo/BFO_0000015 process http://purl.obolibrary.org/obo/BFO_0000003 occurrent An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that inheres in or is borne by other entities. Every instance of A requires some specific instance of B which must always be the same. http://purl.obolibrary.org/obo/BFO_0000023 role http://purl.obolibrary.org/obo/BFO_0000017 realizable entity A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/BFO_0000002 continuant A continuant that is dependent on one or other independent continuant bearers. For every instance of A requires some instance of (an independent continuant type) B but which instance of B serves can change from time to time. http://purl.obolibrary.org/obo/BFO_0000040 material entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. http://purl.obolibrary.org/obo/IAO_0000078 curation status specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part http://purl.obolibrary.org/obo/IAO_0000027 data item Data about an ontology part is a data item about a part of an ontology, for example a term http://purl.obolibrary.org/obo/IAO_0000225 obsolescence reason specification http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part The reason for which a term has been deprecated. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. http://purl.obolibrary.org/obo/IAO_0000409 denotator type http://purl.obolibrary.org/obo/IAO_0000102 data about an ontology part A denotator type indicates how a term should be interpreted from an ontological perspective. http://purl.obolibrary.org/obo/PATO_0000122 length http://purl.obolibrary.org/obo/PATO_0001708 1-D extent A 1-D extent quality which is equal to the distance between two points. http://purl.obolibrary.org/obo/PATO_0001374 ploidy http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A cellular quality inhering in a bearer by virtue of the bearer's number of homologous sets of chromosomes in the nucleus or primary chromosome-containing compartment of the cell, each set essentially coding for all the biological traits of the organism. http://purl.obolibrary.org/obo/PATO_0001375 haploid http://purl.obolibrary.org/obo/PATO_0001393 euploid A ploidy quality inhering in a bearer by virtue of the bearer's containing a single set of homologous chromosomes. http://purl.obolibrary.org/obo/PATO_0001396 cellular quality http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality A monadic quality of continuant that exists at the cellular level of organisation. http://purl.obolibrary.org/obo/PATO_0001547 quality of a gas http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in a bearer by virtue of the bearer's exhibiting the physical characteristics of an entity consisting of particles that have neither a defined volume nor defined shape. http://purl.obolibrary.org/obo/PATO_0001548 quality of a liquid http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A physical quality inhering in an entity exhibiting the physical characteristics of an amorphous (non-crystalline) form of matter between a gas and a solid that has a definite volume, but no definite shape. http://purl.obolibrary.org/obo/PATO_0001995 organismal quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality that inheres in an entire organism or part of an organism. http://purl.obolibrary.org/obo/PR_000000001 protein http://purl.obolibrary.org/obo/PR_000018263 amino acid chain An amino acid chain that is canonically produced de novo by ribosome-mediated translation of a genetically-encoded mRNA, and any derivatives thereof. http://purl.obolibrary.org/obo/PR_000001004 CD4 molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD4 gene or a 1:1 ortholog thereof. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It is the primary receptor for HIV-1. CD4 has four immunoglobulin-like domains in its extracellular region that share the same structure, but can differ in sequence. http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that has a core domain composition consisting of an extracellular N-terminal domain that adopts an immunoglobulin fold, a transmembrane domain, and an intracellular C-terminal domain with a single copy of the Immunoreceptor tyrosine-based activation motif (Pfam:PF02189) (ITAM). It constitutes the invariant subunit of the T cell antigen receptor (TCR). TCR is a surface receptor on T cells responsible for recognizing MHC-restricted antigens and initiating the cellular immune response. http://purl.obolibrary.org/obo/GO_0140014 mitotic nuclear division http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell. http://purl.obolibrary.org/obo/CL_0001061 abnormal cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. http://purl.obolibrary.org/obo/GO_0120039 plasma membrane bounded cell projection morphogenesis http://purl.obolibrary.org/obo/GO_0048858 cell projection morphogenesis The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0030030 cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. http://purl.obolibrary.org/obo/GO_0062013 positive regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0062014 negative regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0120158 positive regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0150052 regulation of postsynapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that modulates the frequency, rate or extent of postsynapse assembly, the aggregation, arrangement and bonding together of a set of components to form a postsynapse. http://purl.obolibrary.org/obo/GO_0140238 presynaptic endocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse A vesicle-mediated transport process in which the presynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. http://purl.obolibrary.org/obo/GO_0120186 negative regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_0150099 neuron-glial cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling that mediates the transfer of information from a neuron to a glial cell. This signaling has been shown to be mediated by various molecules released by different types of neurons, e.g. glutamate, gamma-amino butyric acid (GABA), noradrenaline, acetylcholine, dopamine and adenosine. http://purl.obolibrary.org/obo/CL_4023161 unipolar brush cell http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron An excitatory glutamatergic interneuron found in the granular layer of the cerebellar cortex and also in the granule cell domain of the cochlear nucleus. Unipolar brush cells have a round or oval cell body with usually a single short dendrite that ends in a brush-like tuft of short dendrites unique to them known as dendrioles. http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical http://purl.obolibrary.org/obo/PHIPO_0001218 chemical phenotype A growth phenotype which describes the absence of change of individuals or populations after exposure to a specific chemical (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001309 normal growth on benomyl http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to benomyl (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001310 normal growth on carbendazim http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to carbendazim (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001311 normal growth on chlorothalonil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to chlorothalonil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001312 normal growth on zoxamide http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to zoxamide (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001313 resistance to zoxamide http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to zoxamide. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001314 sensitive to zoxamide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to zoxamide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001315 normal growth on cymoxanil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to cymoxanil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001316 resistance to cymoxanil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cymoxanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001317 sensitive to cymoxanil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cymoxanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001318 normal growth on metalaxyl http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to metalaxyl (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001319 resistance to metalaxyl http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to metalaxyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001320 sensitive to metalaxyl http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to metalaxyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001321 normal growth on flumorph http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to flumorph (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001322 resistance to flumorph http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to flumorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001323 sensitive to flumorph http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to flumorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/CHEBI_229543 sulbactam(1-) http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of sulbactam resulting from the deprotonation of the carboxy group; Major species at pH 7.3. http://purl.obolibrary.org/obo/GO_0014000 morula development http://purl.obolibrary.org/obo/GO_0009790 embryo development The process whose specific outcome is the progression of the morula over time. The morula is a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/CL_4301582 CBX Purkinje Gaba_1 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) A Purkinje cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pcp2 (Mmus), Stk17b (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1152 CBX Purkinje Gaba_1. http://purl.obolibrary.org/obo/CL_4307043 Astro-TE NN_2 Mcm6 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301592 Astro-TE NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mcm6 (Mmus), Egfr (Mmus), Pcsk6 (Mmus). It is distinguished from other Astro-TE NN_2 cells by expression of Mcm6. These cells are located in the Hippocampal region , in or close to the regions: Dentate gyrus, molecular layer, Dentate gyrus, polymorph layer, Dentate gyrus, granule cell layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5223 Astro-TE NN_2. http://purl.obolibrary.org/obo/CHEBI_747325 additive http://purl.obolibrary.org/obo/CHEBI_51086 chemical role a role for a chemical additive to a mixture http://purl.obolibrary.org/obo/CHEBI_16914 salicylic acid http://purl.obolibrary.org/obo/CHEBI_25389 monohydroxybenzoic acid A monohydroxybenzoic acid that is benzoic acid with a hydroxy group at the ortho position. It is obtained from the bark of the white willow and wintergreen leaves. http://purl.obolibrary.org/obo/CHEBI_23451 cyclitol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom. http://purl.obolibrary.org/obo/CHEBI_25830 p-quinones http://purl.obolibrary.org/obo/CHEBI_36141 quinone A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring. http://purl.obolibrary.org/obo/CHEBI_26588 1,3,5-triazines http://purl.obolibrary.org/obo/CHEBI_38102 triazines Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure. http://purl.obolibrary.org/obo/CHEBI_26912 oxolanes http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any oxacycle having an oxolane (tetrahydrofuran) skeleton. http://purl.obolibrary.org/obo/CHEBI_27955 streptamine http://purl.obolibrary.org/obo/CHEBI_61689 amino cyclitol An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups. http://purl.obolibrary.org/obo/CHEBI_31011 valerate http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals. http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated. http://purl.obolibrary.org/obo/CHEBI_36059 hydroxy monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion Any monocarboxylic acid anion carrying at least one hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_36834 3-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid Any hydroxy steroid carrying a hydroxy group at position 3. http://purl.obolibrary.org/obo/CHEBI_38102 triazines http://purl.obolibrary.org/obo/CHEBI_50893 azaarene Compounds based on a triazine skeleton. http://purl.obolibrary.org/obo/CHEBI_38338 aminopyrimidine http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines A member of the class of pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives. http://purl.obolibrary.org/obo/CHEBI_51270 tetracenes http://purl.obolibrary.org/obo/CHEBI_51269 acenes Compounds containing a tetracene skeleton. http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion http://purl.obolibrary.org/obo/CHEBI_26079 phosphoric acid derivative An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated. http://purl.obolibrary.org/obo/CHEBI_623918 nikkomycin Z http://purl.obolibrary.org/obo/CHEBI_59668 nikkomycin A uridine-based nucleoside-peptide antibiotic which inhibits fungal chitin biosynthesis by inhibiting chitin synthase. http://purl.obolibrary.org/obo/CHEBI_64708 one-carbon compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity An organic molecular entity containing a single carbon atom (C1). http://purl.obolibrary.org/obo/CHEBI_6923 miconazole http://purl.obolibrary.org/obo/CHEBI_87069 imidazole antifungal drug A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. http://purl.obolibrary.org/obo/CHEBI_72581 rotenones http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone Members of the class of rotenoid which consists of a 6a,12a-dihydrochromeno[3,4-b]chromen-12(6H)-one skeleton and its substituted products. http://purl.obolibrary.org/obo/CHEBI_75772 Saccharomyces cerevisiae metabolite http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ). http://purl.obolibrary.org/obo/CHEBI_76507 marine metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced during a metabolic reaction in marine macro- and microorganisms. http://purl.obolibrary.org/obo/CHEBI_22478 amino alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group. http://purl.obolibrary.org/obo/CHEBI_24068 fluoroamino acid http://purl.obolibrary.org/obo/CHEBI_37143 organofluorine compound An organofluorine compound that consists of an amino acid substituted by a fluoro group. http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. http://purl.obolibrary.org/obo/CHEBI_60809 adjuvant http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself. http://purl.obolibrary.org/obo/CHEBI_72768 aryl hydrocarbon receptor agonist http://purl.obolibrary.org/obo/CHEBI_48705 agonist An agonist that binds to and activates aryl hydrocarbon receptors (AhRs). http://purl.obolibrary.org/obo/CHEBI_76206 xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced by metabolism of a xenobiotic compound. http://purl.obolibrary.org/obo/CHEBI_133011 oxytetracycline zwitterion http://purl.obolibrary.org/obo/CHEBI_144644 a tetracycline zwitterion A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the adjacent tertiary amino group of oxytetracycline; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_133598 chlortetracycline(1-) http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the major structure of chlortetracycline at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_133833 benznidazole http://purl.obolibrary.org/obo/CHEBI_29347 monocarboxylic acid amide A monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitroimidazol-1-yl)acetic acid with the aromatic amino group of benzylamine. Used for treatment of Chagas disease. http://purl.obolibrary.org/obo/CHEBI_134179 volatile organic compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule Any organic compound having an initial boiling point less than or equal to 250 °C (482 °F) measured at a standard atmospheric pressure of 101.3 kPa. http://purl.obolibrary.org/obo/CHEBI_138856 oxolinic acid http://purl.obolibrary.org/obo/CHEBI_86324 quinolone antibiotic A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the treatment of bacterial infections in cattle, pigs and poultry. http://purl.obolibrary.org/obo/CHEBI_149836 tigecycline http://purl.obolibrary.org/obo/CHEBI_139592 tertiary alpha-hydroxy ketone Tetracycline in which the hydroxy group at position 5 and the methyl group at position 6 are replaced by hydrogen, and with a dimethylamino substituent and an (N-tert-butylglycyl)amino substituent at positions 7 and 9, respectively. A glycylcycline antibiotic, it has activity against a broad range of Gram-positive and Gram-negative bacteria, including tetracycline-resistant organisms. It is used for the intravenous treatment of complicated skin and skin structure infections caused by susceptible organisms. http://purl.obolibrary.org/obo/CHEBI_15022 electron donor http://purl.obolibrary.org/obo/CHEBI_17891 donor A molecular entity that can transfer an electron to another molecular entity. http://purl.obolibrary.org/obo/CHEBI_15138 sulfide(2-) http://purl.obolibrary.org/obo/CHEBI_79388 divalent inorganic anion A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide. http://purl.obolibrary.org/obo/CHEBI_15339 acceptor http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity. http://purl.obolibrary.org/obo/CHEBI_15354 choline http://purl.obolibrary.org/obo/CHEBI_23217 cholines A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. http://purl.obolibrary.org/obo/CHEBI_15369 actinomycin http://purl.obolibrary.org/obo/CHEBI_23239 chromopeptide A large group of antibiotics isolated from various species of Streptomyces and characterised by having a substituted phenoxazine ring linked to two cyclic heterodetic peptides. http://purl.obolibrary.org/obo/CHEBI_15693 aldose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n ≥ 2) and their intramolecular hemiacetals. http://purl.obolibrary.org/obo/CHEBI_15740 formate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects. http://purl.obolibrary.org/obo/CHEBI_15986 polynucleotide http://purl.obolibrary.org/obo/CHEBI_33695 information biomacromolecule A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues. http://purl.obolibrary.org/obo/CHEBI_16042 halide anion http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion A monoatomic monoanion resulting from the addition of an electron to any halogen atom. http://purl.obolibrary.org/obo/CHEBI_16134 ammonia http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms. http://purl.obolibrary.org/obo/CHEBI_16136 hydrogen sulfide http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen. http://purl.obolibrary.org/obo/CHEBI_16189 sulfate http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid. http://purl.obolibrary.org/obo/CHEBI_16199 urea http://purl.obolibrary.org/obo/CHEBI_29347 monocarboxylic acid amide A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). http://purl.obolibrary.org/obo/CHEBI_16215 phosphonate(2-) http://purl.obolibrary.org/obo/CHEBI_79388 divalent inorganic anion A divalent inorganic anion obtained by removal of both protons from phosphonic acid http://purl.obolibrary.org/obo/CHEBI_16240 hydrogen peroxide http://purl.obolibrary.org/obo/CHEBI_26523 reactive oxygen species An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond. http://purl.obolibrary.org/obo/CHEBI_16247 phospholipid http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides. http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates. http://purl.obolibrary.org/obo/CHEBI_16704 uridine http://purl.obolibrary.org/obo/CHEBI_27242 uridines A ribonucleoside composed of a molecule of uracil attached to a ribofuranose moiety via a β‒N1-glycosidic bond. http://purl.obolibrary.org/obo/CHEBI_16716 benzene http://purl.obolibrary.org/obo/CHEBI_33842 aromatic annulene A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised π system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system. http://purl.obolibrary.org/obo/CHEBI_17029 chitin http://purl.obolibrary.org/obo/CHEBI_22506 aminoglycan An aminoglycan consisting of β-(1→4)-linked N-acetyl-D-glucosamine residues. http://purl.obolibrary.org/obo/CHEBI_17076 streptomycin http://purl.obolibrary.org/obo/CHEBI_87114 antibiotic fungicide A amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose An aldohexose used as a source of energy and metabolic intermediate. http://purl.obolibrary.org/obo/CHEBI_17359 sulfite http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3). http://purl.obolibrary.org/obo/CHEBI_17514 cyanide http://purl.obolibrary.org/obo/CHEBI_36828 pseudohalide anion A pseudohalide anion that is the conjugate base of hydrogen cyanide. http://purl.obolibrary.org/obo/CHEBI_17544 hydrogencarbonate http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion The carbon oxoanion resulting from the removal of a proton from carbonic acid. http://purl.obolibrary.org/obo/CHEBI_17658 tylosin http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde A macrolide antibiotic that is tylonolide having mono- and diglycosyl moieties attached to two of its hydroxy groups. It is found naturally as a fermentation product of Streptomyces fradiae. http://purl.obolibrary.org/obo/CHEBI_17698 chloramphenicol http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. http://purl.obolibrary.org/obo/CHEBI_17790 methanol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group. http://purl.obolibrary.org/obo/CHEBI_17792 organohalogen compound http://purl.obolibrary.org/obo/CHEBI_37578 halide A compound containing at least one carbon-halogen bond (where X is a halogen atom). http://purl.obolibrary.org/obo/CHEBI_17822 serine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An α-amino acid that is alanine substituted at position 3 by a hydroxy group. http://purl.obolibrary.org/obo/CHEBI_17833 gentamycin http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic Any of a group of aminoglycoside antibiotics produced by fermentation of some Micromonospora spp. http://purl.obolibrary.org/obo/CHEBI_17883 hydrogen chloride http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms. http://purl.obolibrary.org/obo/CHEBI_17891 donor http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity. http://purl.obolibrary.org/obo/CHEBI_18154 polysaccharide http://purl.obolibrary.org/obo/CHEBI_167559 glycan A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues. http://purl.obolibrary.org/obo/CHEBI_18257 ornithine http://purl.obolibrary.org/obo/CHEBI_83925 non-proteinogenic alpha-amino acid An α-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5. http://purl.obolibrary.org/obo/CHEBI_18282 nucleobase http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound That part of DNA or RNA that may be involved in pairing. http://purl.obolibrary.org/obo/CHEBI_18367 phosphate(3-) http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion A phosphate ion that is the conjugate base of hydrogenphosphate. http://purl.obolibrary.org/obo/CHEBI_18407 hydrogen cyanide http://purl.obolibrary.org/obo/CHEBI_33405 hydracid A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom http://purl.obolibrary.org/obo/CHEBI_22153 acaricide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance used to destroy pests of the subclass Acari (mites and ticks). http://purl.obolibrary.org/obo/CHEBI_22718 benzoates http://purl.obolibrary.org/obo/CHEBI_91007 aromatic carboxylate A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid. http://purl.obolibrary.org/obo/CHEBI_23217 cholines http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion A quaternary ammonium ion based on the choline ion and its substituted derivatives thereof. http://purl.obolibrary.org/obo/CHEBI_23888 drug http://purl.obolibrary.org/obo/CHEBI_52217 pharmaceutical Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. http://purl.obolibrary.org/obo/CHEBI_24433 group http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A defined linked collection of atoms or a single atom within a molecular entity. http://purl.obolibrary.org/obo/CHEBI_24621 hormone http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. http://purl.obolibrary.org/obo/CHEBI_24913 isoprenoid http://purl.obolibrary.org/obo/CHEBI_18059 lipid Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives. http://purl.obolibrary.org/obo/CHEBI_25389 monohydroxybenzoic acid http://purl.obolibrary.org/obo/CHEBI_24676 hydroxybenzoic acid Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring. http://purl.obolibrary.org/obo/CHEBI_25442 mycotoxin http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite Poisonous substance produced by fungi. http://purl.obolibrary.org/obo/CHEBI_25676 oligopeptide http://purl.obolibrary.org/obo/CHEBI_16670 peptide A peptide containing a relatively small number of amino acids. http://purl.obolibrary.org/obo/CHEBI_25704 organic sulfate http://purl.obolibrary.org/obo/CHEBI_26820 sulfates Compounds of the general formula SO3HOR where R is an organyl group http://purl.obolibrary.org/obo/CHEBI_25728 osmolyte http://purl.obolibrary.org/obo/CHEBI_24432 biological role A solute used by a cell under water stress to maintain cell volume. http://purl.obolibrary.org/obo/CHEBI_25903 peptide antibiotic http://purl.obolibrary.org/obo/CHEBI_16670 peptide A chemically diverse class of peptides that exhibit antimicrobial properties. http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin. http://purl.obolibrary.org/obo/CHEBI_26094 benzenedicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid A member of the class of benzoic acids in that consists of benzene substituted by two carboxy groups (A closed class). http://purl.obolibrary.org/obo/CHEBI_26188 polyketide http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Natural and synthetic compounds containing alternating carbonyl and methylene groups ('β-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides. http://purl.obolibrary.org/obo/CHEBI_26649 serine derivative http://purl.obolibrary.org/obo/CHEBI_83821 amino-acid derivative An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues. http://purl.obolibrary.org/obo/CHEBI_26666 short-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid. http://purl.obolibrary.org/obo/CHEBI_2676 amoxicillin http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen A penicillin in which the substituent at position 6 of the penam ring is a 2-amino-2-(4-hydroxyphenyl)acetamido group. http://purl.obolibrary.org/obo/CHEBI_26819 sulfuric ester http://purl.obolibrary.org/obo/CHEBI_37826 sulfuric acid derivative An ester of an alcohol and sulfuric acid. http://purl.obolibrary.org/obo/CHEBI_27027 micronutrient http://purl.obolibrary.org/obo/CHEBI_33284 nutrient Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. http://purl.obolibrary.org/obo/CHEBI_27096 trichlorobenzene http://purl.obolibrary.org/obo/CHEBI_23132 chlorobenzenes Any member of the class of chlorobenzenes carrying three chloro substituents at unspecified positions. http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group http://purl.obolibrary.org/obo/CHEBI_37838 carboacyl group A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid. http://purl.obolibrary.org/obo/CHEBI_27208 unsaturated fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid containing at least one C=C or C≡C bond. http://purl.obolibrary.org/obo/CHEBI_27644 chlortetracycline http://purl.obolibrary.org/obo/CHEBI_139592 tertiary alpha-hydroxy ketone A member of the class of tetracyclines with formula C22H23ClN2O8 isolated from Streptomyces aureofaciens. http://purl.obolibrary.org/obo/CHEBI_27701 oxytetracycline http://purl.obolibrary.org/obo/CHEBI_26895 tetracyclines A tetracycline used for treatment of infections caused by a variety of Gram positive and Gram negative microorganisms including Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae (respiratory infections), and Diplococcus pneumoniae. http://purl.obolibrary.org/obo/CHEBI_27902 tetracycline http://purl.obolibrary.org/obo/CHEBI_139592 tertiary alpha-hydroxy ketone A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. http://purl.obolibrary.org/obo/CHEBI_28616 carbamic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised. http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid. http://purl.obolibrary.org/obo/CHEBI_30746 benzoic acid http://purl.obolibrary.org/obo/CHEBI_22723 benzoic acids A compound comprising a benzene ring core carrying a carboxylic acid substituent. http://purl.obolibrary.org/obo/CHEBI_30762 salicylate http://purl.obolibrary.org/obo/CHEBI_25388 monohydroxybenzoate A monohydroxybenzoate that is the conjugate base of salicylic acid. http://purl.obolibrary.org/obo/CHEBI_30879 alcohol http://purl.obolibrary.org/obo/CHEBI_33822 organic hydroxy compound A compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom. http://purl.obolibrary.org/obo/CHEBI_32544 nicotinate http://purl.obolibrary.org/obo/CHEBI_38181 pyridinemonocarboxylate A pyridinemonocarboxylate that is the conjugate base of nicotinic acid, arising from deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_32600 tetracene http://purl.obolibrary.org/obo/CHEBI_35297 acene An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement. http://purl.obolibrary.org/obo/CHEBI_33249 organyl group http://purl.obolibrary.org/obo/CHEBI_51447 organic univalent group Any organic substituent group, regardless of functional type, having one free valence at a carbon atom. http://purl.obolibrary.org/obo/CHEBI_33252 atomic nucleus http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle A nucleus is the positively charged central portion of an atom, excluding the orbital electrons. http://purl.obolibrary.org/obo/CHEBI_33284 nutrient http://purl.obolibrary.org/obo/CHEBI_78295 food component A nutrient is a food component that an organism uses to survive and grow. http://purl.obolibrary.org/obo/CHEBI_33447 phospho sugar http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid. http://purl.obolibrary.org/obo/CHEBI_33462 phosphonate(1-) http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion A monovalent inorganic anion obtained by deprotonation of one of the two OH groups in phosphonic acid. http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid http://purl.obolibrary.org/obo/CHEBI_15986 polynucleotide A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid. http://purl.obolibrary.org/obo/CHEBI_33709 amino acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid A carboxylic acid containing one or more amino groups. http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside http://purl.obolibrary.org/obo/CHEBI_21731 N-glycosyl compound An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents. http://purl.obolibrary.org/obo/CHEBI_35107 azane http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride Saturated acyclic nitrogen hydrides having the general formula NnHn+2. http://purl.obolibrary.org/obo/CHEBI_35190 diterpene http://purl.obolibrary.org/obo/CHEBI_35186 terpene A C20 terpene. http://purl.obolibrary.org/obo/CHEBI_35267 quaternary ammonium ion http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative A derivative of ammonium, NH4+, in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups. http://purl.obolibrary.org/obo/CHEBI_35443 anthelminthic drug http://purl.obolibrary.org/obo/CHEBI_35442 antiparasitic agent Substance intended to kill parasitic worms (helminths). http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion Any dicarboxylic acid anion that is a monoanion obtained by the deprotonation of only one of the carboxy groups of the dicarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_35819 branched-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid in which the parent hydrocarbon chain has one or more alkyl substituents; a common component in animal and bacterial lipids. The fatty acyl chain is usually saturated and the substituent a methyl group; however, unsaturated BCFAs are found in marine animals, and branches other than methyl are found in microbial lipids. http://purl.obolibrary.org/obo/CHEBI_35820 antiprotozoal drug http://purl.obolibrary.org/obo/CHEBI_36043 antimicrobial drug Any antimicrobial drug which is used to treat or prevent protozoal infections. http://purl.obolibrary.org/obo/CHEBI_36080 protein http://purl.obolibrary.org/obo/PR_000018263 amino acid chain A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome. http://purl.obolibrary.org/obo/CHEBI_37527 acid http://purl.obolibrary.org/obo/CHEBI_51086 chemical role An acid is a molecular entity capable of donating a hydron (Brønsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). http://purl.obolibrary.org/obo/CHEBI_37806 penicillanic acid http://purl.obolibrary.org/obo/CHEBI_25865 penicillanic acids A penam that consists of 3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane bearing a carboxy group at position 2 and having (2S,5R)-configuration. http://purl.obolibrary.org/obo/CHEBI_38068 antimalarial http://purl.obolibrary.org/obo/CHEBI_64915 antiplasmodial drug A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. http://purl.obolibrary.org/obo/CHEBI_38181 pyridinemonocarboxylate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of a pyridinemonocarboxylic acid. A 'closed class'. http://purl.obolibrary.org/obo/CHEBI_48001 protein synthesis inhibitor http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. http://purl.obolibrary.org/obo/CHEBI_48360 amphiprotic solvent http://purl.obolibrary.org/obo/CHEBI_48359 protophilic solvent Self-ionizing solvent possessing both characteristics of Brønsted acids and bases. http://purl.obolibrary.org/obo/CHEBI_4877 ethambutol http://purl.obolibrary.org/obo/CHEBI_23981 ethanolamines An ethylenediamine derivative that is ethane-1,2-diamine in which one hydrogen attached to each of the nitrogens is sutstituted by a 1-hydroxybutan-2-yl group (S,S-configuration). It is a bacteriostatic antimycobacterial drug, effective against Mycobacterium tuberculosis and some other mycobacteria. It is used (as the dihydrochloride salt) in combination with other antituberculous drugs in the treatment of pulmonary and extrapulmonary tuberculosis; resistant strains of M. tuberculosis are readily produced if ethambutol is used alone. http://purl.obolibrary.org/obo/CHEBI_50247 antidote http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any protective agent counteracting or neutralizing the action of poisons. http://purl.obolibrary.org/obo/CHEBI_50406 probe http://purl.obolibrary.org/obo/CHEBI_33232 application A role played by a molecular entity used to study the microscopic environment. http://purl.obolibrary.org/obo/CHEBI_50699 oligosaccharide http://purl.obolibrary.org/obo/CHEBI_167559 glycan A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues. http://purl.obolibrary.org/obo/CHEBI_50910 neurotoxin http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A poison that interferes with the functions of the nervous system. http://purl.obolibrary.org/obo/CHEBI_51086 chemical role http://purl.obolibrary.org/obo/CHEBI_50906 role A role played by the molecular entity or part thereof within a chemical context. http://purl.obolibrary.org/obo/CHEBI_52726 proteasome inhibitor http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug that blocks the action of proteasomes, cellular complexes that break down proteins. http://purl.obolibrary.org/obo/CHEBI_5435 piperidine-2,6-dione http://purl.obolibrary.org/obo/CHEBI_48589 piperidones A dicarboximide that is piperidine which is substituted by oxo groups at positions 2 and 6. http://purl.obolibrary.org/obo/CHEBI_58942 cationic amino-acid residue http://purl.obolibrary.org/obo/CHEBI_64769 organic cationic group An amino-acid residue protonated on nitrogen. http://purl.obolibrary.org/obo/CHEBI_58951 short-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6). http://purl.obolibrary.org/obo/CHEBI_58958 organosulfate oxoanion http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion An organic anion of general formula RS(=O)2O(−) where R is an organyl group. http://purl.obolibrary.org/obo/CHEBI_59066 oxolinate http://purl.obolibrary.org/obo/CHEBI_38773 quinolinemonocarboxylate Conjugate base of oxolinic acid. http://purl.obolibrary.org/obo/CHEBI_59202 straight-chain fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid whose skeletal carbon atoms form an unbranched open chain. http://purl.obolibrary.org/obo/CHEBI_59203 straight-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid. http://purl.obolibrary.org/obo/CHEBI_59635 organophosphonate oxoanion http://purl.obolibrary.org/obo/CHEBI_36360 phosphorus oxoacids and derivatives An organic phosphonic acid derivative in which one or more oxygen atoms of the phosphonate group(s) has been deprotonated. http://purl.obolibrary.org/obo/CHEBI_59740 nucleophilic reagent http://purl.obolibrary.org/obo/CHEBI_39144 Lewis base A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons. http://purl.obolibrary.org/obo/CHEBI_59814 L-alpha-amino acid anion http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion Conjugate base of an L-α-amino acid arising from deprotonation of the C-1 carboxy group. http://purl.obolibrary.org/obo/CHEBI_59869 L-alpha-amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_78608 alpha-amino-acid zwitterion Zwitterionic form of an L-α-amino acid having an anionic carboxy group and a protonated amino group. http://purl.obolibrary.org/obo/CHEBI_60242 monovalent inorganic cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one. http://purl.obolibrary.org/obo/CHEBI_60466 peptide zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged. http://purl.obolibrary.org/obo/CHEBI_60643 NMDA receptor antagonist http://purl.obolibrary.org/obo/CHEBI_60798 excitatory amino acid antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. http://purl.obolibrary.org/obo/CHEBI_60915 diastereoisomeric mixture http://purl.obolibrary.org/obo/CHEBI_60004 mixture A mixture composed of two or more diastereoisomers (stereoisomers not related as mirror images). http://purl.obolibrary.org/obo/CHEBI_63248 oxidising agent http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance that removes electrons from another reactant in a redox reaction. http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds. http://purl.obolibrary.org/obo/CHEBI_64769 organic cationic group http://purl.obolibrary.org/obo/CHEBI_64766 cationic group A cationic group that contains carbon. http://purl.obolibrary.org/obo/CHEBI_64911 antimitotic http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Any compound that inhibits cell division (mitosis). http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any molecule that consists of at least one carbon atom as part of the electrically neutral entity. http://purl.obolibrary.org/obo/CHEBI_73336 vulnerary http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug used in treating and healing of wounds. http://purl.obolibrary.org/obo/CHEBI_73754 thiosugar http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative in which one or more of the oxygens or hydroxy groups of the parent carbohydrate is replaced by sulfur or -SR, where R can be hydrogen or any group. http://purl.obolibrary.org/obo/CHEBI_76395 EC 2.3.1.48 (histone acetyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48). http://purl.obolibrary.org/obo/CHEBI_76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76834 EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*). http://purl.obolibrary.org/obo/CHEBI_76789 EC 2.4.1.* (hexosyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76662 EC 2.4.* (glycosyltransferase) inhibitor An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any hexosyltransferase (EC 2.4.1.*). http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*). http://purl.obolibrary.org/obo/CHEBI_76964 Penicillium metabolite http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite Any fungal metabolite produced during a metabolic reaction in Penicillium. http://purl.obolibrary.org/obo/CHEBI_77853 persistent organic pollutant http://purl.obolibrary.org/obo/CHEBI_78298 environmental contaminant Any environmental contaminant that is resistant to environmental degradation through photolytic, biological or chemical processes. Such substances can have significant impact on health and the environment, as they persist in the environment, bioaccumulate in animal tissue and so biomagnify in food chains. http://purl.obolibrary.org/obo/CHEBI_77941 EC 3.5.1.4 (amidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4). http://purl.obolibrary.org/obo/CHEBI_78675 fundamental metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced by all living cells. http://purl.obolibrary.org/obo/CHEBI_79091 EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76812 EC 2.7.11.* (protein-serine/threonine kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24). http://purl.obolibrary.org/obo/CHEBI_79314 flame retardant http://purl.obolibrary.org/obo/CHEBI_33232 application Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire. http://purl.obolibrary.org/obo/CHEBI_79388 divalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of two. http://purl.obolibrary.org/obo/CHEBI_86478 antibiotic antifungal agent http://purl.obolibrary.org/obo/CHEBI_33285 heteroorganic entity Heteroorganic entities that are microbial metabolites (or compounds derived from them) which have significant antifungal properties. http://purl.obolibrary.org/obo/CHEBI_90799 dipeptide zwitterion http://purl.obolibrary.org/obo/CHEBI_60466 peptide zwitterion Any peptide zwitterion comprising two amino acid residues. Major structure at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_29258 dihydrogenphosphite http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion A monovalent inorganic anion obtained by deprotonation of phosphorous acid. http://purl.obolibrary.org/obo/CHEBI_29259 hydrogenphosphite http://purl.obolibrary.org/obo/CHEBI_79388 divalent inorganic anion A divalent inorganic anion resulting from the removal of a proton from two of the hydroxy groups of phosphorous acid. http://purl.obolibrary.org/obo/CHEBI_29340 hydridonitrate(2-) http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride A divalent inorganic anion resulting from the removal of two protons from ammonia. http://purl.obolibrary.org/obo/CHEBI_2955 azithromycin http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic A macrolide antibiotic useful for the treatment of bacterial infections. http://purl.obolibrary.org/obo/CHEBI_29687 teicoplanin http://purl.obolibrary.org/obo/CHEBI_60004 mixture A complex mixture of related natural products isolated from the fermentation broth of a strain of Actinoplanes teichomyceticus comprising five major components (teicoplanin A2-1 through A2-5), a hydrolysis component (teicoplanin A3-1), and four minor components (teicoplanin RS-1 through RS-4). An antibiotic with a similar spectrum of activity to vancomycin, it is used to treat serious Gram-positive bacterial infections, including methicillin-resistant Staphylococcus aureus and Enterococcus faecalis. http://purl.obolibrary.org/obo/CHEBI_29699 tunicamycin http://purl.obolibrary.org/obo/CHEBI_60004 mixture A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety. http://purl.obolibrary.org/obo/CHEBI_3015 benomyl http://purl.obolibrary.org/obo/CHEBI_87064 benzimidazolylcarbamate fungicide A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. http://purl.obolibrary.org/obo/CHEBI_31014 tetracosanoate http://purl.obolibrary.org/obo/CHEBI_83955 2-saturated fatty acid anion A straight-chain saturated fatty acid anion that is the conjugate base of tetracosanoic acid (lignoceric acid), formed by deprotonation of the carboxy group. http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_24433 group Any substituent group which does not contain carbon. http://purl.obolibrary.org/obo/CHEBI_33338 aryl group http://purl.obolibrary.org/obo/CHEBI_33248 hydrocarbyl group A group derived from an arene by removal of a hydrogen atom from a ring carbon atom. http://purl.obolibrary.org/obo/CHEBI_33543 sulfonate http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion The sulfur oxoanion formed by deprotonation of sulfonic acid. http://purl.obolibrary.org/obo/CHEBI_33658 arene http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon Any monocyclic or polycyclic aromatic hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_33702 polyatomic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation A cation consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_34995 teicoplanin A2-1 http://purl.obolibrary.org/obo/CHEBI_34994 teicoplanin A2 A teicoplanin A2 that has (4Z)-dec-4-enoyl as the variable N-acyl group. http://purl.obolibrary.org/obo/CHEBI_34996 teicoplanin A2-3 http://purl.obolibrary.org/obo/CHEBI_34994 teicoplanin A2 A teicoplanin A2 that has decanoyl as the variable N-acyl group. http://purl.obolibrary.org/obo/CHEBI_34997 teicoplanin A2-4 http://purl.obolibrary.org/obo/CHEBI_34994 teicoplanin A2 A teicoplanin A2 that has 8-methyldecanoyl as the variable N-acyl group. http://purl.obolibrary.org/obo/CHEBI_34998 teicoplanin A2-5 http://purl.obolibrary.org/obo/CHEBI_34994 teicoplanin A2 A teicoplanin A2 that has 9-methyldecanoyl as the variable N-acyl group. http://purl.obolibrary.org/obo/CHEBI_34999 teicoplanin A3-1 http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes A glycopeptide consisting of a macropolycyclic heptapeptide in which a phenolic hydroxy group has been converted to its α-D-mannoside while a secondary alcohol group has been converted to the corresponding 2-acetamido-2-deoxy-β-D-glucoside. http://purl.obolibrary.org/obo/CHEBI_38716 carboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion Any dianion containing at least one carboxy group. http://purl.obolibrary.org/obo/CHEBI_41275 1H-benzimidazole http://purl.obolibrary.org/obo/CHEBI_36622 benzimidazole The 1H-tautomer of benzimidazole. http://purl.obolibrary.org/obo/CHEBI_44137 tiamulin http://purl.obolibrary.org/obo/CHEBI_16385 organic sulfide A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) for the treatment of swine dysentery caused by Serpulina hyodysenteriae. http://purl.obolibrary.org/obo/CHEBI_45064 phosphite(3-) http://purl.obolibrary.org/obo/CHEBI_79387 trivalent inorganic anion A trivalent inorganic anion obtained by removal of all three protons from phosphorous acid. http://purl.obolibrary.org/obo/CHEBI_46633 carbapenems http://purl.obolibrary.org/obo/CHEBI_27933 beta-lactam antibiotic The class of β-lactam antibiotics that whose members have a carbapenem skeleton which is variously substituted at positions 3, 4, and 6. http://purl.obolibrary.org/obo/CHEBI_49020 hormone antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. http://purl.obolibrary.org/obo/CHEBI_50313 onium cation http://purl.obolibrary.org/obo/CHEBI_50312 onium compound Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families. http://purl.obolibrary.org/obo/CHEBI_50344 avermectin http://purl.obolibrary.org/obo/CHEBI_25106 macrolide Any of the macrolides obtained as fermentation products from the bacterium Streptomyces avermitilis and consisting of a 16-membered macrocyclic backbone that is fused both benzofuran and spiroketal functions and contains a disaccharide substituent. They have significant anthelmintic and insecticidal properties. http://purl.obolibrary.org/obo/CHEBI_51308 dinitrile http://purl.obolibrary.org/obo/CHEBI_18379 nitrile A dinitrile is a compound containing two nitrile groups. http://purl.obolibrary.org/obo/CHEBI_53658 ceftriaxone(1-) http://purl.obolibrary.org/obo/CHEBI_52440 cephalosporin carboxylic acid anion A cephalosporin carboxylis acid anion having 2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetylamino and [(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl side-groups, formed by proton loss from the carboxy group of ceftriaxone. http://purl.obolibrary.org/obo/CHEBI_600103 daptomycin http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A polypeptide comprising N-decanoyltryptophan, asparagine, aspartic acid, threonine, glycine, ornithine, aspartic acid, D-alanine, aspartic acid, glycine, D-serine, threo-3-methylglutamic acid and 3-anthraniloylalanine (also known as kynurinine) coupled in sequence and lactonised by condensation of the carboxylic acid group of the 3-anthraniloylalanine with the alcohol group of the threonine residue. http://purl.obolibrary.org/obo/CHEBI_62031 polar amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group. http://purl.obolibrary.org/obo/CHEBI_62247 (1R,2S)-epoxypropylphosphonate(1-) http://purl.obolibrary.org/obo/CHEBI_59635 organophosphonate oxoanion An organophosphonate oxoanion obtained by deprotonation of one of the two phosphonate OH groups of (1R,2S)-epoxypropylphosphonic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_64228 tunicamycin A0 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64237 EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76816 EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins. http://purl.obolibrary.org/obo/CHEBI_64245 tunicamycin A1 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64246 tunicamycin A2 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64248 tunicamycin B1 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64250 tunicamycin B2 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64255 tunicamycin B3 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64256 tunicamycin C1 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64257 tunicamycin C2 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64271 tunicamycin D1 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_64272 tunicamycin D2 http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. http://purl.obolibrary.org/obo/CHEBI_71321 fusidate http://purl.obolibrary.org/obo/CHEBI_50160 steroid acid anion A steroid acid anion that is the conjugate base of fusidic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_73678 tobramycin(5+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the five amino groups of tobramycin. http://purl.obolibrary.org/obo/CHEBI_78379 EC 2.5.1.7 (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7). http://purl.obolibrary.org/obo/CHEBI_83414 alkyl sulfate(1-) http://purl.obolibrary.org/obo/CHEBI_58958 organosulfate oxoanion An organosulfate oxoanion obtained by deprotonation of the sulfo group of any alkyl sulfate; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_85251 teicoplanin A2-2 http://purl.obolibrary.org/obo/CHEBI_34994 teicoplanin A2 A teicoplanin A2 that has 8-methylnonanoyl as the variable N-acyl group. http://purl.obolibrary.org/obo/CHEBI_87015 anilide fungicide http://purl.obolibrary.org/obo/CHEBI_60600 amide fungicide Any amide fungicide whose structure contains an anilide group. http://purl.obolibrary.org/obo/CHEBI_87036 benzimidazole fungicide http://purl.obolibrary.org/obo/CHEBI_22715 benzimidazoles Compounds that contain a benzimidazole moiety as a key feature of their structure and which have been used as fungicides. http://purl.obolibrary.org/obo/CHEBI_87068 imidazole fungicide http://purl.obolibrary.org/obo/CHEBI_86420 imidazole antifungal agent Any imidazole antifungal agent that has been used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_87197 dichlorophenyl dicarboximide fungicide http://purl.obolibrary.org/obo/CHEBI_23697 dichlorobenzene A dicarboximide fungicide in which the nitrogen of the dicarboximide group is substituted by a dichlorophenyl group. http://purl.obolibrary.org/obo/CHEBI_4031 cyclosporin A http://purl.obolibrary.org/obo/CHEBI_24613 homodetic cyclic peptide A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. http://purl.obolibrary.org/obo/CHEBI_404903 ertapenem http://purl.obolibrary.org/obo/CHEBI_46770 pyrrolidinecarboxamide Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract. http://purl.obolibrary.org/obo/CHEBI_40909 azoxystrobin http://purl.obolibrary.org/obo/CHEBI_18379 nitrile An aryloxypyrimidine having a 4,6-diphenoxypyrimidine skeleton in which one of the phenyl rings is cyano-substituted at C-2 and the other carries a 2-methoxy-1-(methoxycarbonyl)vinyl substituent, also at C-2. An inhibitor of mitochondrial respiration by blocking electron transfer between cytochromes b and c1, it is used widely as a fungicide in agriculture. http://purl.obolibrary.org/obo/CHEBI_41948 eflornithine http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid A fluoroamino acid that is ornithine substituted by a difluoromethyl group at position 2. http://purl.obolibrary.org/obo/CHEBI_43968 meropenem http://purl.obolibrary.org/obo/CHEBI_16385 organic sulfide A carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively. http://purl.obolibrary.org/obo/CHEBI_50694 minocycline http://purl.obolibrary.org/obo/CHEBI_139592 tertiary alpha-hydroxy ketone A tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5. http://purl.obolibrary.org/obo/CHEBI_50845 doxycycline http://purl.obolibrary.org/obo/CHEBI_26895 tetracyclines Tetracycline in which the 5β-hydrogen is replaced by a hydroxy group, while the 6α-hydroxy group is replaced by hydrogen. A semi-synthetic tetracycline antibiotic, it is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with chronic obstructive pulmonary disease (COPD), and adult periodontitis. http://purl.obolibrary.org/obo/CHEBI_51374 GABA agent http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. http://purl.obolibrary.org/obo/CHEBI_60071 ertapenem(1-) http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion The mono-anion resulting from the removal of a proton from one of the carboxyic acid groups of ertapenem. http://purl.obolibrary.org/obo/CHEBI_64268 erythromycin A(1+) http://purl.obolibrary.org/obo/CHEBI_64290 erythromycin cation An erythromycin cation that is the conjugate acid of erythromycin A, arising from protonation of the tertiary amino group on the 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl residue; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_69136 latrunculin A http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. http://purl.obolibrary.org/obo/CHEBI_7025 mupirocin http://purl.obolibrary.org/obo/CHEBI_27136 triol An α,β-unsaturated ester resulting from the formal condensation of the alcoholic hydroxy group of 9-hydroxynonanoic acid with the carboxy group of (2E)-4-[(2S)-tetrahydro-2H-pyran-2-yl]-3-methylbut-2-enoic acid in which the tetrahydropyranyl ring is substituted at positions 3 and 4 by hydroxy groups and at position 5 by a {(2S,3S)-3-[(2S,3S)-3-hydroxybutan-2-yl]oxiran-2-yl}methyl group. Originally isolated from the Gram-negative bacterium Pseudomonas fluorescens, it is used as a topical antibiotic for the treatment of Gram-positive bacterial infections. http://purl.obolibrary.org/obo/CHEBI_74159 D-cycloserine zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion A zwitterion resulting from the transfer of a proton from the ring nitrogen to the primary amino group of D-cycloserine. The major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_7508 framycetin http://purl.obolibrary.org/obo/CHEBI_47779 aminoglycoside A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine B. http://purl.obolibrary.org/obo/CHEBI_75929 D-cycloserine(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation that is the conjugate acid of D-cycloserine, obtained by protonation of the amino group. http://purl.obolibrary.org/obo/CHEBI_81783 tricyclazole http://purl.obolibrary.org/obo/CHEBI_48908 triazolobenzothiazole A triazolobenzothiazole that is [1,2,4]triazolo[3,4-b][1,3]benzothiazole which is substituted at position 5 by a methyl group. A fungicide used for the control of rice blast, it is not approved for use within the European Union. http://purl.obolibrary.org/obo/CHEBI_86484 methoxyacrylate strobilurin antifungal agent http://purl.obolibrary.org/obo/CHEBI_25248 methyl ester Any strobilurin antifungal agent that contains a methoxyacrylate group. http://purl.obolibrary.org/obo/CHEBI_87208 anilinopyrimidine fungicide http://purl.obolibrary.org/obo/CHEBI_87207 pyrimidine fungicide Any pyrimidine fungicide in which the pyrimidine ring is substituted by the nitrogen of an aniline moiety. http://purl.obolibrary.org/obo/CHEBI_5827 hymexazol http://purl.obolibrary.org/obo/CHEBI_55373 isoxazoles A member of the class of isoxazoles carrying hydroxy and methyl substituents at positions 3 and 5 respectively. It is used worldwide as a systemic soil and seed fungicide for the control of diseases caused by Fusarium, Aphanomyces, Pythium, and Corticium spp. in rice, sugarbeet, fodderbeet, vegetables, cucurbits, and ornamentals. http://purl.obolibrary.org/obo/CHEBI_59668 nikkomycin http://purl.obolibrary.org/obo/CHEBI_36988 5'-deoxyribonucleoside A class of nucleoside-peptide antibiotics which inhibit fungal chitin biosynthesis by inhibiting chitin synthase. Generally consist of a heterocyclic moiety (usually a nucleobase), an amino hexuronic acid and an amino acid containing a pyridine ring. http://purl.obolibrary.org/obo/CHEBI_59792 thioacetal http://purl.obolibrary.org/obo/CHEBI_33261 organosulfur compound The sulfur analogue of 'acetal'. The term includes monothioacetals having the structure R2C(OR')(SR') (subclass monothioketals, R ≠ H); and dithioacetals having the structure R2C(SR')2 (subclass dithioketals, R ≠ H, R' ≠ H). http://purl.obolibrary.org/obo/CHEBI_59864 depigmentation drug http://purl.obolibrary.org/obo/CHEBI_23888 drug Any drug used to depigment skin, normally by decreasing the excretion of melanin from melanocytes. http://purl.obolibrary.org/obo/CHEBI_60690 nitrogen-containing fatty acid http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid Any fatty acid containing nitrogen as either a substituent or a replacement for a methylene carbon. http://purl.obolibrary.org/obo/CHEBI_61007 amino fatty acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion A nitrogen-containing fatty acid anion arising from deprotonation of the carboxy group of any amino fatty acid. http://purl.obolibrary.org/obo/CHEBI_64641 divalent inorganic cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation An inorganic cation with a valency of two. http://purl.obolibrary.org/obo/CHEBI_72316 virulence factor http://purl.obolibrary.org/obo/CHEBI_27026 toxin Any toxin secreted by bacteria, viruses, fungi or protozoa enabling them to achieve colonisation of a niche in the host, inhibit or evade the host's immune response, enter and exit cells, or obtain nutrition from the host. http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*). http://purl.obolibrary.org/obo/CHEBI_76841 EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*). http://purl.obolibrary.org/obo/CHEBI_76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76661 EC 2.3.* (acyltransferase) inhibitor An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*). http://purl.obolibrary.org/obo/CHEBI_68481 mTOR inhibitor http://purl.obolibrary.org/obo/CHEBI_37699 protein kinase inhibitor A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer. http://purl.obolibrary.org/obo/CHEBI_75282 ergosterol biosynthesis inhibitor http://purl.obolibrary.org/obo/CHEBI_83317 sterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. http://purl.obolibrary.org/obo/CHEBI_82891 glucocorticoid receptor antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist An antagonist that binds to and deactivates glucocorticoid receptors. http://purl.obolibrary.org/obo/CHEBI_82894 (R)-miconazole http://purl.obolibrary.org/obo/CHEBI_82892 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has R configuration. http://purl.obolibrary.org/obo/CHEBI_82897 (S)-miconazole http://purl.obolibrary.org/obo/CHEBI_82892 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has S) configuration. http://purl.obolibrary.org/obo/CHEBI_77102 EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor http://purl.obolibrary.org/obo/CHEBI_76729 EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using a quinone or related compound as acceptor (EC 1.3.5.*). http://purl.obolibrary.org/obo/CHEBI_77315 spectinomycin(2+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the secondary amino groups of spectinomycin. http://purl.obolibrary.org/obo/CHEBI_77318 pregnane X receptor agonist http://purl.obolibrary.org/obo/CHEBI_48705 agonist An agonist that selectively binds to and activates a pregnane X receptor. http://purl.obolibrary.org/obo/CHEBI_77569 trovafloxacin(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation that is the conjugate acid of trovafloxacin, obtained by protonation of the primary amino group. http://purl.obolibrary.org/obo/CHEBI_77615 terbinafine(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation that is the conjugate acid of terbinafine, obtained by protonation of the amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_77733 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound A tertiary amino compound that is 3,4-dimethoxyphenylethylamine in which the hydrogens attached to the nitrogen are replaced by a methyl group and a 4-cyano-4-(3,4-dimethoxyphenyl)-5-methylhexyl group. http://purl.obolibrary.org/obo/CHEBI_77734 dexverapamil http://purl.obolibrary.org/obo/CHEBI_77733 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil. http://purl.obolibrary.org/obo/CHEBI_77736 (S)-verapamil http://purl.obolibrary.org/obo/CHEBI_77733 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has S configuration. http://purl.obolibrary.org/obo/CHEBI_77737 dexverapamil(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An ammonium ion resulting from the protonation of the tertiary amino group of dexverapamil. http://purl.obolibrary.org/obo/CHEBI_77738 (S)-verapamil(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An ammonium ion resulting from the protonation of the tertiary amino group of (S)-verapamil. http://purl.obolibrary.org/obo/CHEBI_78692 1-[biphenyl-4-yl(phenyl)methyl]imidazole http://purl.obolibrary.org/obo/CHEBI_24780 imidazoles A member of the class of imidazoles carrying an α-(biphenyl-4-yl)benzyl substituent at position 1. http://purl.obolibrary.org/obo/CHEBI_78696 cercosporamide http://purl.obolibrary.org/obo/CHEBI_38922 dibenzofurans A member of the class of dibenzofurans that is a potent broad spectrum antifungal agent isolated from the fungus Cercosporidium henningsii. http://purl.obolibrary.org/obo/CHEBI_78787 dithiocarbamic acids http://purl.obolibrary.org/obo/CHEBI_50492 thiocarbonyl compound Any organic acid in which both oxygens of a carbamic acid have been replaced by sulfur. http://purl.obolibrary.org/obo/CHEBI_83734 sterol demethylation inhibitor http://purl.obolibrary.org/obo/CHEBI_35718 antifungal agent A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis. http://purl.obolibrary.org/obo/CHEBI_83986 ethylenebis(dithiocarbamic acid) http://purl.obolibrary.org/obo/CHEBI_78787 dithiocarbamic acids A dithiocarbamic acid resulting from the formal addition of a molecule of carbon disulfide to each amino group of ethylenediamine. http://purl.obolibrary.org/obo/CHEBI_84292 dithiocarbamate anions http://purl.obolibrary.org/obo/CHEBI_84291 organic sulfur anion Any organic sulfur anion resulting from the removal of a proton from any N-substituted dithiocarbamic acid. http://purl.obolibrary.org/obo/CHEBI_9448 terbinafine http://purl.obolibrary.org/obo/CHEBI_87127 allylamine antifungal drug A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. http://purl.obolibrary.org/obo/CHEBI_9763 trovafloxacin http://purl.obolibrary.org/obo/CHEBI_50994 primary amino compound A 1,8-naphthyridine derivative that is 4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid bearing additional 2,4-difluorophenyl, fluoro and 6-amino-3-azabicyclo[3.1.0]hex-3-yl substituents at positions 1, 6 and 7 respectively. A broad-spectrum antibiotic that was withdrawn from the market due to risk of liver failure. http://purl.obolibrary.org/obo/CHEBI_87132 morpholine antifungal agent http://purl.obolibrary.org/obo/CHEBI_38785 morpholines A member of the class of morpholines that has significant antifungal properties. http://purl.obolibrary.org/obo/CHEBI_87185 florfenicol http://purl.obolibrary.org/obo/CHEBI_140325 secondary carboxamide A carboxamide that is the N-dichloroacetyl derivative of (1R,2S)-2-amino-3-fluoro-1-[4-(methanesulfonyl)phenyl]propan-1-ol. A synthetic veterinary antibiotic that is used for treatment of bovine respiratory disease and foot rot; also used in aquaculture. http://purl.obolibrary.org/obo/CHEBI_87200 dicarboximide antifungal agent http://purl.obolibrary.org/obo/CHEBI_35356 dicarboximide A compound that has significant antifungal properties whose structure contains a dicarboximide moiety. http://purl.obolibrary.org/obo/CHEBI_87204 pyrimidine antifungal agent http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines A member of the class of pyrimidines that has significant antifungal properties. http://purl.obolibrary.org/obo/CHEBI_87209 virginiamycin http://purl.obolibrary.org/obo/CHEBI_60004 mixture A mixture of cyclic polypeptide streptogramin antibiotics produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. The two major components are virginiamycin M1 (also known as pristinamycin IIA) and virginiamycin S1. Virginiamycin has been widely used as a growth promotion agent in livestock and has been to have bacteriostatic activity against Gram-positive organisms such as staphylococci and streptococci. http://purl.obolibrary.org/obo/CHEBI_88225 beta-lactam antibiotic allergen http://purl.obolibrary.org/obo/CHEBI_27933 beta-lactam antibiotic Any β-lactam antibiotic which causes the onset of an allergic reaction. http://purl.obolibrary.org/obo/CHEBI_9700 tridemorph http://purl.obolibrary.org/obo/CHEBI_87134 morpholine fungicide A mixture of 4-alkyl-2,6-dimethylmorpholines, where 'alkyl' is a mixture of C11 to C14 homologues of which 60-70% is tridecyl. A systemic fungicide, it is no longer approved for use within the European Union. http://purl.obolibrary.org/obo/CHEBI_9948 verapamil http://purl.obolibrary.org/obo/CHEBI_60911 racemate A racemate comprising equimolar amounts of dexverapamil and (S)-verapamil. An L-type calcium channel blocker of the phenylalkylamine class, it is used (particularly as the hydrochloride salt) in the treatment of hypertension, angina pectoris and cardiac arrhythmia, and as a preventive medication for migraine. http://purl.obolibrary.org/obo/CL_0000000 cell http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. http://purl.obolibrary.org/obo/CL_0000005 neural crest derived fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is derived from the neural crest. http://purl.obolibrary.org/obo/CL_0000006 neuronal receptor cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell Any sensory receptor cell that is a(n) neuron and is capable of some detection of stimulus involved in sensory perception. http://purl.obolibrary.org/obo/CL_0000007 early embryonic cell (metazoa) http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell found in the embryo before the formation of all the gem layers is complete. http://purl.obolibrary.org/obo/CL_0000008 migratory cranial neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Cell that is part of the migratory cranial neural crest population. Migratory cranial neural crest cells develop from premigratory cranial neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/CL_0000011 migratory trunk neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Cell that is part of the migratory trunk neural crest population. Migratory trunk neural crest cells develop from premigratory trunk neural crest cells and have undergone epithelial to mesenchymal transition and delamination. http://purl.obolibrary.org/obo/CL_0000014 germ line stem cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell A stem cell that is the precursor of gametes. http://purl.obolibrary.org/obo/CL_0000021 female germ cell http://purl.obolibrary.org/obo/CL_0000586 germ cell Female germ cell is a germ cell that supports female gamete production. http://purl.obolibrary.org/obo/CL_0000022 female germ line stem cell http://purl.obolibrary.org/obo/CL_0000021 female germ cell A stem cell that is the precursor of female gametes. http://purl.obolibrary.org/obo/CL_0000023 oocyte http://purl.obolibrary.org/obo/CL_0000021 female germ cell A female germ cell that has entered meiosis. http://purl.obolibrary.org/obo/CL_0000024 oogonial cell http://purl.obolibrary.org/obo/CL_0000021 female germ cell An undifferentiated germ cell that proliferates rapidly and gives rise to oocytes. http://purl.obolibrary.org/obo/CL_0000025 egg cell http://purl.obolibrary.org/obo/CL_0000675 female gamete A female gamete where meiosis has progressed to metaphase II and is able to participate in fertilization. http://purl.obolibrary.org/obo/CL_0000027 smooth muscle cell neural crest derived http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell derived from the neural crest. http://purl.obolibrary.org/obo/CL_0000029 neural crest derived neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that develops from some migratory neural crest cell. http://purl.obolibrary.org/obo/CL_0000030 glioblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that develops form the neuroectoderm. Glioblast has the potential to differentiate into various types of glial cells, including astrocytes and oligodendrocytes. http://purl.obolibrary.org/obo/CL_0000031 neuroblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A cell that will develop into a neuron often after a migration phase. http://purl.obolibrary.org/obo/CL_0000034 stem cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A relatively undifferentiated cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/CL_0000035 single fate stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell that self-renews as well as give rise to a single mature cell type. http://purl.obolibrary.org/obo/CL_0000036 epithelial fate stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A somatic stem cell that is committed to an epithelial fate, possessing the capacity for self-renewal and the ability to differentiate into one or more distinct mature cell types of the epithelial lineage. This cell is crucial for the development, homeostasis, repair, and regeneration of epithelial tissues. http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119. http://purl.obolibrary.org/obo/CL_0000038 erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A progenitor cell committed to the erythroid lineage. http://purl.obolibrary.org/obo/CL_0000039 germ line cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is within the developmental lineage of gametes and is able to pass along its genetic material to offspring. http://purl.obolibrary.org/obo/CL_0000040 monoblast http://purl.obolibrary.org/obo/CL_0002194 monopoietic cell A myeloid progenitor cell committed to the monocyte lineage. This cell is CD11b-positive, has basophilic cytoplasm, euchromatin, and the presence of a nucleolus. http://purl.obolibrary.org/obo/CL_0000047 neural stem cell http://purl.obolibrary.org/obo/CL_0002319 neural cell An undifferentiated neural cell that originates from the neuroectoderm and has the capacity both to perpetually self-renew without differentiating and to generate multiple central nervous system neuronal and glial cell types. http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell that can give rise to multiple lineages of cells. http://purl.obolibrary.org/obo/CL_0000049 common myeloid progenitor http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. http://purl.obolibrary.org/obo/CL_0000050 megakaryocyte-erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell committed to the megakaryocyte and erythroid lineages. http://purl.obolibrary.org/obo/CL_0000051 common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A oligopotent progenitor cell committed to the lymphoid lineage. http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A stem cell from which all cells of the body can form. http://purl.obolibrary.org/obo/CL_0000056 myoblast http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell A cell that is commited to differentiating into a muscle cell. Embryonic myoblasts develop from the mesoderm. They undergo proliferation, migrate to their various sites, and then differentiate into the appropriate form of myocytes. Myoblasts also occur as transient populations of cells in muscles undergoing repair. http://purl.obolibrary.org/obo/CL_0000057 fibroblast http://purl.obolibrary.org/obo/CL_0000499 stromal cell A connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. Flattened and irregular in outline with branching processes; appear fusiform or spindle-shaped. http://purl.obolibrary.org/obo/CL_0000058 chondroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that is typically non-terminally differentiated, secretes an avascular, GAG rich matrix; is not buried in cartilage tissue matrix, retains the ability to divide, located adjacent to cartilage tissue (including within the perichondrium), and develops from prechondroblast (and thus prechondrogenic) cell. http://purl.obolibrary.org/obo/CL_0000064 ciliated cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that has a filiform extrusion of the cell surface. http://purl.obolibrary.org/obo/CL_0000065 ependymal cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A neuroepithelial glial cell, derived from a radial glial cell originating from the neuroectoderm, lines the ventricles of the brain and the central canal of the spinal cord. This cell is characterized by the presence of cilia on its apical surface, which can be motile or non-motile. http://purl.obolibrary.org/obo/CL_0000066 epithelial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is usually found in a two-dimensional sheet with a free surface. The cell has a cytoskeleton that allows for tight cell to cell contact and for cell polarity where apical part is directed towards the lumen and the basal part to the basal lamina. http://purl.obolibrary.org/obo/CL_0000067 ciliated epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that has a cilia. http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell that is part of a duct. http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree An endothelial cell that lines the vasculature. http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A flat, squamous-like epithelial cell of mesodermal origin. It forms the mesothelium, which lines the body's serous cavities including the pleural, peritoneal, and pericardial spaces. This cell plays a crucial role in synthesizing and secreting lubricants, such as glycosaminoglycans and surfactants, which minimize friction between adjacent tissues during movement. http://purl.obolibrary.org/obo/CL_0000078 peridermal cell http://purl.obolibrary.org/obo/CL_0000362 epidermal cell Any squamous epithelial cell that is part of some periderm. http://purl.obolibrary.org/obo/CL_0000080 circulating cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell which moves among different tissues of the body, via blood, lymph, or other medium. http://purl.obolibrary.org/obo/CL_0000081 blood cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell A cell found predominately in the blood. http://purl.obolibrary.org/obo/CL_0000082 epithelial cell of lung http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract An epithelial cell of the lung. http://purl.obolibrary.org/obo/CL_0000084 T cell http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/CL_0000092 osteoclast http://purl.obolibrary.org/obo/CL_0001035 bone cell A specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. This cell has the following markers: tartrate-resistant acid phosphatase type 5-positive, PU.1-positive, c-fos-positive, nuclear factor NF-kappa-B p100 subunit-positive, tumor necrosis factor receptor superfamily member 11A-positive and macrophage colony-stimulating factor 1 receptor-positive. http://purl.obolibrary.org/obo/CL_0000094 granulocyte http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte A leukocyte with abundant granules in the cytoplasm. http://purl.obolibrary.org/obo/CL_0000098 sensory epithelial cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell A specialized epithelial cell involved in sensory perception. Restricted to special sense organs of the olfactory, gustatory, and vestibulocochlear receptor systems; contain sensory cells surrounded by supportive, non-receptive cells. http://purl.obolibrary.org/obo/CL_0000099 interneuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Most generally any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions. http://purl.obolibrary.org/obo/CL_0000100 motor neuron http://purl.obolibrary.org/obo/CL_0000527 efferent neuron An efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes or inhibits movement. http://purl.obolibrary.org/obo/CL_0000101 sensory neuron http://purl.obolibrary.org/obo/CL_0000526 afferent neuron Any neuron having a sensory function; an afferent neuron conveying sensory impulses. http://purl.obolibrary.org/obo/CL_0000107 autonomic neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron whose cell body is within an autonomic ganglion. http://purl.obolibrary.org/obo/CL_0000108 cholinergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that uses acetylcholine as a vesicular neurotransmitter. http://purl.obolibrary.org/obo/CL_0000113 mononuclear phagocyte http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte A vertebrate phagocyte with a single nucleus. http://purl.obolibrary.org/obo/CL_0000114 surface ectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell An ectodermal cell that is part of the external ectoderm, forming the outermost layer of the developing embryo. It is characterized by its polarized nature, with distinct apical and basal surfaces (Ferrante Jr., Reinke, & Stanley, 1995). Surface ectodermal cell gives rise to the epidermis, hair follicles, nails, sensory organs, and specialized structures like the apical ectodermal ridge crucial for limb development (Skoufa et al., 2024). http://purl.obolibrary.org/obo/CL_0000115 endothelial cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. In mammals, endothelial cell has vimentin filaments and is derived from the mesoderm. http://purl.obolibrary.org/obo/CL_0000118 basket cell http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron Basket cells are inhibitory GABAergic interneurons of the brain. In general, dendrites of basket cells are free branching and contain smooth spines. Axons are highly branched. The branched axonal arborizations give rise to basket-like structures that surround the soma of the target cell. Basket cells form axo-somatic synapses, meaning their synapses target somas of other cells. http://purl.obolibrary.org/obo/CL_0000119 cerebellar Golgi cell http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron Large intrinsic neuron located in the granule layer of the cerebellar cortex that extends its dendrites into the molecular layer where they receive contact from parallel fibers. The axon of the Golgi cell ramifies densely in the granule layer and enters into a complex arrangement with mossy fiber terminals and granule cell dendrites to form the cerebellar glomerulus. Llinas, Walton and Lang. In The Synaptic Organization of the Brain. 5th ed. 2004. http://purl.obolibrary.org/obo/CL_0000120 granule cell http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the vertebrate central nervous system that is small in size. This general class includes small neurons in the granular layer of the cerebellar cortex, cerebral cortex neurons that are not pyramidal cells and small neurons without axons found in the olfactory bulb. http://purl.obolibrary.org/obo/CL_0000121 Purkinje cell http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron An inhibitory neuron and the sole output neuron of the cerebellar cortex, the Purkinje cell's soma is located between the granular and molecular layers of the cerebellum. It is one of the largest neural cells in the mammalian brain, ranging from 50 to 80 micrometres in diameter. Purkinje cells have planar, fan-shaped dendrites that branch extensively with little overlap. This cell type receives synaptic input from parallel fibres, which modulate high-frequency spike activity known as "simple spikes," and climbing fibres, which modulate infrequent calcium spike activity known as "complex spikes". Purkinje cells are involved in motor coordination, particularly in correcting movements in progress. http://purl.obolibrary.org/obo/CL_0000122 stellate neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron that has dendritic processes radiating from the cell body forming a star-like shape. http://purl.obolibrary.org/obo/CL_0000125 glial cell http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell A non-neuronal cell of the nervous system. They not only provide physical support, but also respond to injury, regulate the ionic and chemical composition of the extracellular milieu. Guide neuronal migration during development, and exchange metabolites with neurons. http://purl.obolibrary.org/obo/CL_0000126 macroglial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A neuroglial cell of ectodermal origin, i.e., the astrocytes and oligodendrocytes considered together. http://purl.obolibrary.org/obo/CL_0000127 astrocyte http://purl.obolibrary.org/obo/CL_0000126 macroglial cell A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from 'star' cells) are irregularly shaped with many long processes, including those with 'end feet' which form the glial (limiting) membrane and directly and indirectly contribute to the blood-brain barrier. They regulate the extracellular ionic and chemical environment, and 'reactive astrocytes' (along with microglia) respond to injury. http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte http://purl.obolibrary.org/obo/CL_4023154 myelinating glial cell A class of large neuroglial (macroglial) cells in the central nervous system. Form the insulating myelin sheath of axons in the central nervous system. http://purl.obolibrary.org/obo/CL_0000129 microglial cell http://purl.obolibrary.org/obo/CL_0000878 central nervous system macrophage A transcriptomically distinct central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. http://purl.obolibrary.org/obo/CL_0000131 gut endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that lines the blood and lymphatic vessels of the digestive tract. This cell forms the gut–vascular barrier (GVB) through tight junctions and crosstalk with pericytes and enteric glial cells, regulating the passage of nutrients and immune cells while restricting microbial translocation into the bloodstream. http://purl.obolibrary.org/obo/CL_0000133 neurectodermal cell http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell Ectoderm destined to be nervous tissue. http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. http://purl.obolibrary.org/obo/CL_0000136 adipocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals. Fat is usually stored in the form of triglycerides. http://purl.obolibrary.org/obo/CL_0000138 chondrocyte http://purl.obolibrary.org/obo/CL_0007001 skeletogenic cell A skeletogenic cell that secretes a specialized, avascular, GAG-rich matrix, is embedded in cartilage tissue matrix, retains the ability to divide, and develops from a chondroblast cell. http://purl.obolibrary.org/obo/CL_0000145 professional antigen presenting cell http://purl.obolibrary.org/obo/CL_0000738 leukocyte A cell capable of processing and presenting lipid and protein antigens to T cells in order to initiate an immune response. http://purl.obolibrary.org/obo/CL_0000147 pigment cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell A pigment cell is a cell that contains pigment granules. http://purl.obolibrary.org/obo/CL_0000150 glandular secretory epithelial cell http://purl.obolibrary.org/obo/CL_1100001 secretory epithelial cell An epithelial cell, located in a gland, that is specialised for the synthesis and secretion of specific biomolecules, such as hormones, or mucous. http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that specializes in controlled release of one or more substances. http://purl.obolibrary.org/obo/CL_0000152 exocrine cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of an exocrine gland; i.e. a gland that discharges its secretion via a duct. http://purl.obolibrary.org/obo/CL_0000153 glycosaminoglycan secreting cell http://purl.obolibrary.org/obo/CL_0000447 carbohydrate secreting cell A cell that secretes glycosaminoglycans. http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some protein secretion. http://purl.obolibrary.org/obo/CL_0000163 endocrine cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of an endocrine gland, ductless glands that secrete substances which are released directly into the circulation and which influence metabolism and other body functions. http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A neuron that is capable of some hormone secretion in response to neuronal signals. http://purl.obolibrary.org/obo/CL_0000166 chromaffin cell http://purl.obolibrary.org/obo/CL_0000568 amine precursor uptake and decarboxylation cell A cell that stores epinephrine secretory vesicles. During times of stress, the nervous system signals the vesicles to secrete their hormonal content. Their name derives from their ability to stain a brownish color with chromic salts. Characteristically, they are located in the adrenal medulla and paraganglia of the sympathetic nervous system. http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some peptide hormone secretion. http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell Any secretory cell that is capable of some steroid hormone secretion. http://purl.obolibrary.org/obo/CL_0000183 contractile cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to shorten. http://purl.obolibrary.org/obo/CL_0000187 muscle cell http://purl.obolibrary.org/obo/CL_0000393 electrically responsive cell A mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell A non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. They develop from specialized myoblasts (smooth muscle myoblast). http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is capable of detection of a stimulus involved in sensory perception. http://purl.obolibrary.org/obo/CL_0000206 chemoreceptor cell http://purl.obolibrary.org/obo/CL_0000197 sensory receptor cell A cell specialized to detect chemical substances and relay that information centrally in the nervous system. Chemoreceptors may monitor external stimuli, as in taste and olfaction, or internal stimuli, such as the concentrations of oxygen and carbon dioxide in the blood. http://purl.obolibrary.org/obo/CL_0000209 taste receptor cell http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell A specialized cell involved in gustatory sensory perception. http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell http://purl.obolibrary.org/obo/CL_0000101 sensory neuron A cell specialized in detecting light stimuli that are involved in visual perception. http://purl.obolibrary.org/obo/CL_0000211 electrically active cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose function is determined by the generation or the reception of an electric signal. http://purl.obolibrary.org/obo/CL_0000214 synovial cell http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell A cell located in the synovial joint. http://purl.obolibrary.org/obo/CL_0000218 myelinating Schwann cell http://purl.obolibrary.org/obo/CL_4023154 myelinating glial cell A neuroglial cell of the peripheral nervous system which forms the insulating myelin sheaths of peripheral axons. http://purl.obolibrary.org/obo/CL_0000219 motile cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that moves by its own activities. http://purl.obolibrary.org/obo/CL_0000221 ectodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the outer of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the middle germ layer of the embryo. http://purl.obolibrary.org/obo/CL_0000223 endodermal cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/CL_0000225 anucleate cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that lacks a nucleus. http://purl.obolibrary.org/obo/CL_0000226 single nucleate cell http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A cell with a single nucleus. http://purl.obolibrary.org/obo/CL_0000228 multinucleate cell http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A cell with more than one nucleus. http://purl.obolibrary.org/obo/CL_0000232 erythrocyte http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell A red blood cell. In mammals, mature erythrocytes are biconcave disks containing hemoglobin whose function is to transport oxygen. http://purl.obolibrary.org/obo/CL_0000234 phagocyte http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell Any cell capable of ingesting particulate matter via phagocytosis. http://purl.obolibrary.org/obo/CL_0000235 macrophage http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte A mononuclear phagocyte present in variety of tissues, typically differentiated from monocytes, capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. http://purl.obolibrary.org/obo/CL_0000239 brush border epithelial cell http://purl.obolibrary.org/obo/CL_0000075 columnar/cuboidal epithelial cell An epithelial cell characterized by the presence of a brush border on its apical surface, which increases the surface area for absorption. http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell that in taxon some Eukaryota. http://purl.obolibrary.org/obo/CL_0000287 eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell Any photoreceptor cell that is part of some eye. http://purl.obolibrary.org/obo/CL_0000295 somatotropin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/CL_0000300 gamete http://purl.obolibrary.org/obo/CL_0000586 germ cell A mature sexual reproductive cell having a single set of unpaired chromosomes. http://purl.obolibrary.org/obo/CL_0000307 tracheal epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell found in the trachea. http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell Columnar glandular cell with irregular nucleus, copious granular endoplasmic reticulum and supranuclear granules. Secretes a watery fluid containing proteins known as serous fluid. http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is specialised to accumulate a particular substance(s). http://purl.obolibrary.org/obo/CL_0000329 oxygen accumulating cell http://purl.obolibrary.org/obo/CL_0000000 cell Any cell that is capable of some oxygen transport. http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell A cell derived from the specialized ectoderm flanking each side of the embryonic neural plate, which after the closure of the neural tube, forms masses of cells that migrate out from the dorsal aspect of the neural tube to spread throughout the body. http://purl.obolibrary.org/obo/CL_0000335 mesenchyme condensation cell http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell A mesenchymal cell in embryonic development found in a contracting mass and that gives rise to osteoprogenitors. http://purl.obolibrary.org/obo/CL_0000339 glioblast (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) An early neural cell developing from the early ependymal cell of the neural tube. http://purl.obolibrary.org/obo/CL_0000347 scleral cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the sclera of the eye. http://purl.obolibrary.org/obo/CL_0000348 choroidal cell of the eye http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is part of optic choroid. http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that is part of some extraembryonic structure. http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell An extraembryonic cell that develops from a trophectodermal cell. This cell is found in the outer layer of the blastocyst and can invade other structures in the uterus once the blastocyst implants into the uterine wall. A trophoblast cell is involved in the implantation of the embryo into the uterine wall, placental formation, remodelling of maternal vasculature in the uterus, nutrient and gas exchange, hormone production, and immune modulation to support fetal development. http://purl.obolibrary.org/obo/CL_0000352 epiblast cell http://purl.obolibrary.org/obo/CL_0000052 totipotent stem cell A cell of the outer layer of a blastula that gives rise to the ectoderm after gastrulation. http://purl.obolibrary.org/obo/CL_0000353 blastoderm cell http://purl.obolibrary.org/obo/CL_0000007 early embryonic cell (metazoa) An undifferentiated cell produced by early cleavages of the fertilized egg (zygote). http://purl.obolibrary.org/obo/CL_0000355 multi-potent skeletal muscle stem cell http://purl.obolibrary.org/obo/CL_0000188 cell of skeletal muscle A multifate stem cell found in skeletal muscle than can differentiate into many different cell types, including muscle. Distinct cell type from satellite cell. http://purl.obolibrary.org/obo/CL_0000359 vascular associated smooth muscle cell http://purl.obolibrary.org/obo/CL_4033054 perivascular cell A smooth muscle cell associated with the vasculature. http://purl.obolibrary.org/obo/CL_0000362 epidermal cell http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the integument (the outer layer of an organism). http://purl.obolibrary.org/obo/CL_0000365 animal zygote http://purl.obolibrary.org/obo/CL_0010017 zygote Diploid cell produced by the fusion of sperm cell nucleus and egg cell. http://purl.obolibrary.org/obo/CL_0000393 electrically responsive cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell whose function is determined by its response to an electric signal. http://purl.obolibrary.org/obo/CL_0000397 ganglion interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron Any interneuron that has its soma located in some ganglion. http://purl.obolibrary.org/obo/CL_0000404 electrically signaling cell http://purl.obolibrary.org/obo/CL_0000211 electrically active cell A cell that initiates an electrical signal and passes that signal to another cell. http://purl.obolibrary.org/obo/CL_0000413 haploid cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose nucleus contains a single haploid genome. http://purl.obolibrary.org/obo/CL_0000438 luteinizing hormone secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell A peptide hormone secreting cell pituitary that produces luteinizing hormone. http://purl.obolibrary.org/obo/CL_0000439 prolactin secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone cell that secretes prolactin. http://purl.obolibrary.org/obo/CL_0000440 melanocyte stimulating hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A cell of the intermediate pituitary that produces melanocyte stimulating hormone. http://purl.obolibrary.org/obo/CL_0000451 dendritic cell http://purl.obolibrary.org/obo/CL_0000145 professional antigen presenting cell A cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. These cells are lineage negative (CD3-negative, CD19-negative, CD34-negative, and CD56-negative). http://purl.obolibrary.org/obo/CL_0000458 serotonin secreting cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell type that secretes 5-Hydroxytryptamine (serotonin). http://purl.obolibrary.org/obo/CL_0000459 noradrenergic cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell A cell capable of producting norepiniphrine. Norepiniphrine is a catecholamine with multiple roles including as a hormone and a neurotransmitter. In addition, epiniphrine is synthesized from norepiniphrine by the actions of the phenylethanolamine N-methyltransferase enzyme. http://purl.obolibrary.org/obo/CL_0000467 adrenocorticotropic hormone secreting cell http://purl.obolibrary.org/obo/CL_0000167 peptide hormone secreting cell A peptide hormone secreting cell that produces adrenocorticotropin, or corticotropin. http://purl.obolibrary.org/obo/CL_0000488 visible light photoreceptor cell http://purl.obolibrary.org/obo/CL_0000210 photoreceptor cell A photoreceptor cell that detects visible light. http://purl.obolibrary.org/obo/CL_0000498 inhibitory interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron (also called relay neuron, association neuron or local circuit neuron) is a multipolar neuron which connects afferent neurons and efferent neurons in neural pathways. Like motor neurons, interneuron cell bodies are always located in the central nervous system (CNS). http://purl.obolibrary.org/obo/CL_0000499 stromal cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A connective tissue cell of an organ found in the loose connective tissue. http://purl.obolibrary.org/obo/CL_0000513 cardiac muscle myoblast http://purl.obolibrary.org/obo/CL_0010021 cardiac myoblast A precursor cell destined to differentiate into cardiac muscle cell. http://purl.obolibrary.org/obo/CL_0000514 smooth muscle myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast A precursor cell destined to differentiate into smooth muscle myocytes. http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast A myoblast that differentiates into skeletal muscle fibers. http://purl.obolibrary.org/obo/CL_0000518 phagocyte (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A phagocyte in vertebrates that is able to phagocytosis. http://purl.obolibrary.org/obo/CL_0000521 fungal cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any cell that in taxon some Fungi. http://purl.obolibrary.org/obo/CL_0000525 syncytiotrophoblast cell http://purl.obolibrary.org/obo/CL_0000351 trophoblast cell A cell from the outer syncytial layer of the trophoblast of an early mammalian embryo, directly associated with the maternal blood supply. It secretes hCG in order to maintain progesterone secretion and sustain a pregnancy. http://purl.obolibrary.org/obo/CL_0000526 afferent neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron which conveys sensory information centrally from the periphery. http://purl.obolibrary.org/obo/CL_0000527 efferent neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron which sends impulses peripherally to activate muscles or secretory cells. http://purl.obolibrary.org/obo/CL_0000540 neuron http://purl.obolibrary.org/obo/CL_0002319 neural cell The basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/CL_0000542 lymphocyte http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/CL_0000547 proerythroblast http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An immature, nucleated erythrocyte occupying the stage of erythropoeisis that follows formation of erythroid progenitor cells. This cell is CD71-positive, has both a nucleus and a nucleolus, and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0000549 basophilic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast A nucleated immature erythrocyte, having cytoplasm generally similar to that of the earlier proerythroblast but sometimes even more basophilic, and usually regular in outline. The nucleus is still relatively large, but the chromatin strands are thicker and more deeply staining, giving a coarser appearance; the nucleoli have disappeared. This cell is CD71-positive and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0000550 polychromatophilic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast A nucleated, immature erythrocyte in which the nucleus occupies a relatively smaller part of the cell than in its precursor, the basophilic erythroblast. The cytoplasm is beginning to acquire hemoglobin and thus is no longer a purely basophilic, but takes on acidophilic aspects, which becomes progressively more marked as the cell matures. The chromatin of the nucleus is arranged in coarse, deeply staining clumps. This cell is CD71-positive and lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0000552 orthochromatic erythroblast http://purl.obolibrary.org/obo/CL_0000765 erythroblast The final stage of the nucleated, immature erythrocyte, before nuclear loss. Typically the cytoplasm is described as acidophilic, but it still shows a faint polychromatic tint. The nucleus is small and initially may still have coarse, clumped chromatin, as in its precursor, the polychromatophilic erythroblast, but ultimately it becomes pyknotic, and appears as a deeply staining, blue-black, homogeneous structureless mass. The nucleus is often eccentric and sometimes lobulated. http://purl.obolibrary.org/obo/CL_0000553 megakaryocyte progenitor cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell The earliest cytologically identifiable precursor in the thrombocytic series. This cell is capable of endomitosis and lacks expression of hematopoieitic lineage markers (lin-negative). http://purl.obolibrary.org/obo/CL_0000556 megakaryocyte http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A large hematopoietic cell (50 to 100 micron) with a lobated nucleus. Once mature, this cell undergoes multiple rounds of endomitosis and cytoplasmic restructuring to allow platelet formation and release. http://purl.obolibrary.org/obo/CL_0000557 granulocyte monocyte progenitor cell http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell A hematopoietic progenitor cell that is committed to the granulocyte and monocyte lineages. These cells are CD123-positive, and do not express Gata1 or Gata2 but do express C/EBPa, and Pu.1. http://purl.obolibrary.org/obo/CL_0000558 reticulocyte http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell An immature erythrocyte that changes the protein composition of its plasma membrane by exosome formation and extrusion. The types of protein removed differ between species though removal of the transferrin receptor is apparent in mammals and birds. http://purl.obolibrary.org/obo/CL_0000559 promonocyte http://purl.obolibrary.org/obo/CL_0002194 monopoietic cell A precursor in the monocytic series, being a cell intermediate in development between the monoblast and monocyte. This cell is CD11b-positive and has fine azurophil granules. http://purl.obolibrary.org/obo/CL_0000562 nucleate erythrocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An erythrocyte having a nucleus. http://purl.obolibrary.org/obo/CL_0000566 angioblastic mesenchymal cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A mesenchymal stem cell capable of developing into blood vessel endothelium. http://purl.obolibrary.org/obo/CL_0000568 amine precursor uptake and decarboxylation cell http://purl.obolibrary.org/obo/CL_0000165 neuroendocrine cell A cell that originates in the neural crest, that has certain cytochemical and ultrastructural characteristics and is found scattered throughout the body; types include melanocytes, the cells of the chromaffin system, and cells in the hypothalamus, hypophysis, thyroid, parathyroids, lungs, gastrointestinal tract, and pancreas. This cell type concentrates the amino acid precursors of certain amines and decarboxylate them, forming amines that function as regulators and neurotransmitters. This cell type produces substances such as epinephrine, norepinephrine, dopamine, serotonin, enkephalin, somatostatin, neurotensin, and substance P, the actions of which may affect contiguous cells, nearby groups of cells, or distant cells, thus functioning as local or systemic hormones. The name is an acronym for amine precursor uptake and decarboxylation cell. http://purl.obolibrary.org/obo/CL_0000569 cardiac mesenchymal cell http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell A mesenchymal cell found in the developing heart and that develops into some part of the heart. These cells derive from intra- and extra-cardiac sources, including the endocardium, epicardium, neural crest, and second heart field. http://purl.obolibrary.org/obo/CL_0000573 retinal cone cell http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell One of the two photoreceptor cell types in the vertebrate retina. In cones the photopigment is in invaginations of the cell membrane of the outer segment. Cones are less sensitive to light than rods, but they provide vision with higher spatial and temporal acuity, and the combination of signals from cones with different pigments allows color vision. http://purl.obolibrary.org/obo/CL_0000575 corneal epithelial cell http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of the cornea. http://purl.obolibrary.org/obo/CL_0000576 monocyte http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. http://purl.obolibrary.org/obo/CL_0000586 germ cell http://purl.obolibrary.org/obo/CL_0000039 germ line cell The reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/CL_0000593 androgen secreting cell http://purl.obolibrary.org/obo/CL_0000174 steroid hormone secreting cell A steroid hormone secreting cell that secretes androgen. http://purl.obolibrary.org/obo/CL_0000596 sexual spore http://purl.obolibrary.org/obo/CL_0002369 fungal spore A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. http://purl.obolibrary.org/obo/CL_0000598 pyramidal neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Pyramidal neurons have a pyramid-shaped soma with a single axon, a large apical dendrite and multiple basal dendrites. The apex and an apical dendrite typically point toward the pial surface and other dendrites and an axon emerging from the base. The axons may have local collaterals but also project outside their region. Pyramidal neurons are found in the cerebral cortex, the hippocampus, and the amygdala. http://purl.obolibrary.org/obo/CL_0000604 retinal rod cell http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell One of the two photoreceptor cell types of the vertebrate retina. In rods the photopigment is in stacks of membranous disks separate from the outer cell membrane. Rods are more sensitive to light than cones, but rod mediated vision has less spatial and temporal resolution than cone vision. http://purl.obolibrary.org/obo/CL_0000605 fungal asexual spore http://purl.obolibrary.org/obo/CL_0002369 fungal spore A spore formed following mitosis or mitoses. http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that uses GABA as a vesicular neurotransmitter http://purl.obolibrary.org/obo/CL_0000622 acinar cell http://purl.obolibrary.org/obo/CL_0000154 protein secreting cell A secretory cell that is grouped together with other cells of the same type to form grape shaped clusters known as acini (singular acinus). http://purl.obolibrary.org/obo/CL_0000630 supporting cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell whose primary function is to support other cell types. http://purl.obolibrary.org/obo/CL_0000637 chromophil cell of anterior pituitary gland http://purl.obolibrary.org/obo/CL_2000004 pituitary gland cell A cell that stains readily in the anterior pituitary gland. http://purl.obolibrary.org/obo/CL_0000638 acidophil cell of pars distalis of adenohypophysis http://purl.obolibrary.org/obo/CL_0000637 chromophil cell of anterior pituitary gland An acidophilic chromophil cell that of the anterior pituitary gland. http://purl.obolibrary.org/obo/CL_0000642 folliculostellate cell http://purl.obolibrary.org/obo/CL_2000004 pituitary gland cell An agranular supporting cell of the anterior pituitary (adenohypophysis) that is characterized by a star-like morphology and ability to form follicles. Folliculostellate cells communicate with each other and with endocrine cells via gap junctions. http://purl.obolibrary.org/obo/CL_0000644 Bergmann glial cell http://purl.obolibrary.org/obo/CL_0002603 astrocyte of the cerebellum Type of radial astrocyte in the cerebellar cortex that have their cell bodies in the Purkinje cell layer and processes that extend into the molecular layer, terminating with bulbous endfeet at the pial surface. Bergmann glia express high densities of glutamate transporters that limit diffusion of the neurotransmitter glutamate during its release from synaptic terminals. Besides their role in early development of the cerebellum, Bergmann glia are also required for the pruning or addition of synapses. http://purl.obolibrary.org/obo/CL_0000652 pinealocyte http://purl.obolibrary.org/obo/CL_0002319 neural cell This cell type produces and secretes melatonin and forms the pineal parenchyma. Extending from each cell body, which has a spherical, oval or lobulated mucleus, are one or more tortuous basophilic processes, containing parallel microtubules known as synaptic ribbons. These processes end in expanded terminal buds near capillaries or less, frequently, ependymal cells of the pineal recess. The terminal buds contain granular endoplasmic reticulum, mitochondria and electron-dense cored vesicles, which store monoamines and polypeptide hormones, release of which appears to require sympathetic innervation. http://purl.obolibrary.org/obo/CL_0000666 fenestrated endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell that has small pores, or fenestrations, which allow for the efficient exchange of substances between the blood and surrounding tissues. http://purl.obolibrary.org/obo/CL_0000667 collagen secreting cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell An extracellular matrix secreting cell that secretes collagen. http://purl.obolibrary.org/obo/CL_0000670 primordial germ cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A primordial germ cell is a diploid germ cell precursors that transiently exist in the embryo before they enter into close association with the somatic cells of the gonad and become irreversibly committed as germ cells. http://purl.obolibrary.org/obo/CL_0000675 female gamete http://purl.obolibrary.org/obo/CL_0000300 gamete A mature sexual reproductive cell of the female germline. http://purl.obolibrary.org/obo/CL_0000679 glutamatergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that is capable of some neurotansmission by glutamate secretion. http://purl.obolibrary.org/obo/CL_0000680 muscle precursor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A non-terminally differentiated cell that is capable of developing into a muscle cell. http://purl.obolibrary.org/obo/CL_0000681 radial glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A cell present in the developing CNS. Functions as both a precursor cell and as a scaffold to support neuronal migration. http://purl.obolibrary.org/obo/CL_0000686 cerebrospinal fluid secreting cell http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A columnar/cuboidal epithelial cell that secretes cerebrospinal fluid. http://purl.obolibrary.org/obo/CL_0000691 stellate interneuron http://purl.obolibrary.org/obo/CL_0000122 stellate neuron Any interneuron that has characteristic some stellate morphology. http://purl.obolibrary.org/obo/CL_0000700 dopaminergic neuron http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron A neuron that releases dopamine as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0000706 choroid plexus epithelial cell http://purl.obolibrary.org/obo/CL_0000239 brush border epithelial cell A specialized ependymal cell that is part of the choroid plexus epithelium, responsible for producing cerebrospinal fluid (CSF) by selectively filtering and modifying blood plasma components before secreting it into the brain and spinal cord. This cell is characterized by a brush border on its apical surface, which enhances the secretion of CSF. http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from neural plate and neural crest. http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell http://purl.obolibrary.org/obo/CL_0000034 stem cell A stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell Muscle cell which has as its direct parts myofilaments organized into sarcomeres. http://purl.obolibrary.org/obo/CL_0000738 leukocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell An achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/CL_0000740 retinal ganglion cell http://purl.obolibrary.org/obo/CL_0000540 neuron The set of neurons that receives neural inputs via bipolar, horizontal and amacrine cells. The axons of these cells make up the optic nerve. http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. In mammals, the contractile fiber resembles those of skeletal muscle but are only one third as large in diameter, are richer in sarcoplasm, and contain centrally located instead of peripheral nuclei. http://purl.obolibrary.org/obo/CL_0000763 myeloid cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell A cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/CL_0000764 erythroid lineage cell http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A immature or mature cell in the lineage leading to and including erythrocytes. http://purl.obolibrary.org/obo/CL_0000765 erythroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A nucleated precursor of an erythrocyte that lacks hematopoietic lineage markers. http://purl.obolibrary.org/obo/CL_0000766 myeloid leukocyte http://purl.obolibrary.org/obo/CL_0000763 myeloid cell A cell of the monocyte, granulocyte, or mast cell lineage. http://purl.obolibrary.org/obo/CL_0000778 mononuclear osteoclast http://purl.obolibrary.org/obo/CL_0000113 mononuclear phagocyte A specialized mononuclear osteoclast associated with the absorption and removal of bone, precursor of multinuclear osteoclasts. http://purl.obolibrary.org/obo/CL_0000779 multinuclear osteoclast http://purl.obolibrary.org/obo/CL_0000783 multinucleated phagocyte A specialized multinuclear osteoclast, forming a syncytium through the fusion of mononuclear precursor cells, associated with the absorption and removal of bone. http://purl.obolibrary.org/obo/CL_0000782 myeloid dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A dendritic cell of the myeloid lineage. http://purl.obolibrary.org/obo/CL_0000783 multinucleated phagocyte http://purl.obolibrary.org/obo/CL_0000518 phagocyte (sensu Vertebrata) A phagocyte formed by the fusion of mononuclear phagocytes. http://purl.obolibrary.org/obo/CL_0000827 pro-T cell http://purl.obolibrary.org/obo/CL_0000838 lymphoid lineage restricted progenitor cell A lymphoid progenitor cell of the T cell lineage, with some lineage specific marker expression, but not yet fully committed to the T cell lineage. http://purl.obolibrary.org/obo/CL_0000835 myeloblast http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell The most primitive precursor in the granulocytic series, having fine, evenly distributed chromatin, several nucleoli, a high nuclear-to-cytoplasmic ration (5:1-7:1), and a nongranular basophilic cytoplasm. They reside in the bone marrow. http://purl.obolibrary.org/obo/CL_0000837 hematopoietic multipotent progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans. http://purl.obolibrary.org/obo/CL_0000838 lymphoid lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell restricted to the lymphoid lineage. http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell restricted to the myeloid lineage. http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte A leukocyte with a single non-segmented nucleus in the mature form. http://purl.obolibrary.org/obo/CL_0000850 serotonergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases serotonin as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0000860 classical monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A monocyte that responds rapidly to microbial stimuli by secreting cytokines and antimicrobial factors and which is characterized by high expression of CCR2 in both rodents and humans, negative for the lineage markers CD3, CD19, and CD20, and of larger size than non-classical monocytes. http://purl.obolibrary.org/obo/CL_0000861 elicited macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage which develops from an inflammatory monocyte and is recruited into the tissues in response to injury and infection as part of an inflammatory response. Markers include CD11b-positive, CD68-positive, and F4/80-positive. http://purl.obolibrary.org/obo/CL_0000862 suppressor macrophage http://purl.obolibrary.org/obo/CL_0000861 elicited macrophage A macrophage that suppresses immune responses. http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage A macrophage constitutively resident in a particular tissue under non-inflammatory conditions, and capable of phagocytosing a variety of extracellular particulate material, including immune complexes, microorganisms, and dead cells. http://purl.obolibrary.org/obo/CL_0000878 central nervous system macrophage http://purl.obolibrary.org/obo/CL_0002319 neural cell A tissue-resident macrophage found in the central nervous system. http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell of a hematopoietic lineage. http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell http://purl.obolibrary.org/obo/CL_0000451 dendritic cell Conventional dendritic cell is a dendritic cell that is CD11c-high. http://purl.obolibrary.org/obo/CL_0001021 CD34-positive, CD38-positive common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0000995 CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor A common lymphoid progenitor that is CD10-positive, CD45RA-positive, CD34-positive and CD38-positive. http://purl.obolibrary.org/obo/CL_0001022 CD115-positive monocyte http://purl.obolibrary.org/obo/CL_0001019 CD115-positive monocyte OR common dendritic progenitor CD115-positive monocyte is a monocyte that is CD115-positive and CD11b-positive. http://purl.obolibrary.org/obo/CL_0001024 CD34-positive, CD38-negative hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell CD133-positive hematopoietic stem cell is a hematopoietic stem cell that is CD34-positive, CD90-positive, and CD133-positive. http://purl.obolibrary.org/obo/CL_0001026 CD34-positive, CD38-positive common myeloid progenitor http://purl.obolibrary.org/obo/CL_0001059 common myeloid progenitor, CD34-positive A common myeloid progenitor that is CD34-positive, CD38-positive, IL3ra-low, CD10-negative, CD7-negative, CD45RA-negative, and IL-5Ralpha-negative. http://purl.obolibrary.org/obo/CL_0001027 CD7-negative lymphoid progenitor cell http://purl.obolibrary.org/obo/CL_0001012 CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor CD7-negative lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-negative and CD45RA-negative. http://purl.obolibrary.org/obo/CL_0001028 CD7-positive lymphoid progenitor cell http://purl.obolibrary.org/obo/CL_0000051 common lymphoid progenitor CD7-positive lymphoid progenitor cell is a lymphoid progenitor cell that is CD34-positive, CD7-positive and is CD45RA-negative. http://purl.obolibrary.org/obo/CL_0001029 common dendritic progenitor http://purl.obolibrary.org/obo/CL_0001019 CD115-positive monocyte OR common dendritic progenitor Common dendritic precursor is a hematopoietic progenitor cell that is CD117-low, CD135-positive, CD115-positive and lacks plasma membrane parts for hematopoietic lineage markers. http://purl.obolibrary.org/obo/CL_0001031 cerebellar granule cell http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron An excitatory granule cell with a soma located in the granular layer of cerebellar cortex. A mature cerebellar granule cell has short dendrites with a characteristic claw-like appearance and a long axon that ascends to the molecular layer where it bifurcates (except in non-teleost fish, where it does not bifurcate) and extends mediolaterally to form parallel fibers. http://purl.obolibrary.org/obo/CL_0001032 cortical granule cell http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron Granule cell that is part of the cerebral cortex. http://purl.obolibrary.org/obo/CL_0001035 bone cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A connective tissue cell found in bone. http://purl.obolibrary.org/obo/CL_0001054 CD14-positive monocyte http://purl.obolibrary.org/obo/CL_0000576 monocyte A monocyte that expresses CD14 and is negative for the lineage markers CD3, CD19, and CD20. http://purl.obolibrary.org/obo/CL_0001059 common myeloid progenitor, CD34-positive http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell committed to myeloid lineage, including the megakaryocyte and erythroid lineages. These cells are CD34-positive, and express Gata1, Gata2, C/EBPa, and Pu.1. http://purl.obolibrary.org/obo/CL_0001060 hematopoietic oligopotent progenitor cell, lineage-negative http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. Cell lacks hematopoeitic lineage markers. http://purl.obolibrary.org/obo/CL_0002001 CD34-positive, CD38-positive granulocyte monocyte progenitor http://purl.obolibrary.org/obo/CL_0000557 granulocyte monocyte progenitor cell A granulocyte monocyte progenitor is CD34-positive, CD38-positive, IL-3receptor-alpha-positive and is CD45RA-negative. http://purl.obolibrary.org/obo/CL_0002005 CD34-positive, CD38-positive megakaryocyte erythroid progenitor cell http://purl.obolibrary.org/obo/CL_0000050 megakaryocyte-erythroid progenitor cell A megakaryocyte erythroid progenitor cell is CD34-positive, CD38-positive and is IL3-receptor alpha-negative and CD45RA-negative. http://purl.obolibrary.org/obo/CL_0002009 macrophage dendritic cell progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A progenitor cell that can give rise to plasmacytoid and myeloid dendritic cells, and to monocytes and macrophages. http://purl.obolibrary.org/obo/CL_0002010 pre-conventional dendritic cell http://purl.obolibrary.org/obo/CL_0002031 hematopoietic lineage restricted progenitor cell A lin-negative, MHC-II-negative, CD11c-positive, FLT3-positive cell with intermediate expression of SIRP-alpha. http://purl.obolibrary.org/obo/CL_0002031 hematopoietic lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic progenitor cell that is capable of developing into only one lineage of hematopoietic cells. http://purl.obolibrary.org/obo/CL_0002032 hematopoietic oligopotent progenitor cell http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell A hematopoietic oligopotent progenitor cell that has the ability to differentiate into limited cell types but lacks lineage cell markers and self renewal capabilities. http://purl.obolibrary.org/obo/CL_0002043 CD34-positive, CD38-negative multipotent progenitor cell http://purl.obolibrary.org/obo/CL_0000837 hematopoietic multipotent progenitor cell A hematopoietic multipotent progenitor cell that is CD34-positive, CD38-negative, CD45RA-negative, and CD90-negative. http://purl.obolibrary.org/obo/CL_0002068 Purkinje myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte Specialized cardiac myocyte that is subendocardially interspersed with the regular cardiac muscle cell. They are uninucleate cylindrical cells, associated end-to-end in long rows, continue from the node to the atrioventricular bundle; relatively short compared to ordinary myocytes but are nearly twice their diameter. http://purl.obolibrary.org/obo/CL_0002072 nodal myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte A specialized cardiac myocyte in the sinoatrial and atrioventricular nodes. The cell is slender and fusiform confined to the nodal center, circumferentially arranged around the nodal artery. http://purl.obolibrary.org/obo/CL_0002073 transitional myocyte http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte Specialized cardiac myocyte which is in the internodal tract and atrioventricular node. The cell is more slender than ordinary atrial myocytes and has more myofibrils than nodal myocytes. http://purl.obolibrary.org/obo/CL_0002074 myocardial endocrine cell http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte The myoendocrine cellis a specialized myocyte localized mainly in the right and left atrial appendages, and also scattered within other areas of the atria and along the conductive system in the ventricular septum. The most conspicuous feature distinguishing myoendocrine cells from other atrial myoctyes is the presence of membane-bounded secretory granules (these granules contain precursor of cardiodilatins or atrial natriuretic polypeptides). http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell derived from endoderm. http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell An epithelial cell derived from ectoderm. http://purl.obolibrary.org/obo/CL_0002078 meso-epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell Epithelial cell derived from mesoderm or mesenchyme. http://purl.obolibrary.org/obo/CL_0002085 tanycyte http://purl.obolibrary.org/obo/CL_0000065 ependymal cell A specialized elongated ventricular ependymal cell with one or more processes that extend into the brain parenchyma or associated blood vessels where they contact blood vessel endothelial cells and/or neurons. These cells are found in the ventricles and circumventricular organs of the brain. They are involved in hormonal regulation, gatekeeping molecules between the bloodstream and cerebrospinal fluid, metabolic sensing, and regulating food intake. http://purl.obolibrary.org/obo/CL_0002086 specialized cardiac myocyte http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell A cardiac myocyte that is an excitable cells in the myocardium, specifically in the conducting system of heart. http://purl.obolibrary.org/obo/CL_0002087 nongranular leukocyte http://purl.obolibrary.org/obo/CL_0000738 leukocyte A leukocyte that lacks granules. http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell http://purl.obolibrary.org/obo/CL_0001035 bone cell A cell found in the bone marrow. This can include fibroblasts, macrophages, adipocytes, osteoblasts, osteoclasts, endothelial cells and hematopoietic cells. http://purl.obolibrary.org/obo/CL_0002095 hilus cell of ovary http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A cell in the hilum of the ovary that produces androgens. http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary http://purl.obolibrary.org/obo/CL_0000499 stromal cell A stomal cell of the ovary http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree http://purl.obolibrary.org/obo/CL_0000115 endothelial cell An endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels. http://purl.obolibrary.org/obo/CL_0002144 capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell An endothelial cell found in capillaries. http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell http://purl.obolibrary.org/obo/CL_0002077 ecto-epithelial cell Epithelial cells derived from general body ectoderm and ectoderm placodes. http://purl.obolibrary.org/obo/CL_0002177 folliculostellate cell of pars distalis of adenohypophysis http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A supporting cell of the anterior pituitary gland involved in trophic and catabolic processes; expresses a broad spectrum of cytokeratins indicative of their epithelial nature. http://purl.obolibrary.org/obo/CL_0002191 granulocytopoietic cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A cell involved in the formation of a granulocyte. http://purl.obolibrary.org/obo/CL_0002194 monopoietic cell http://purl.obolibrary.org/obo/CL_0000839 myeloid lineage restricted progenitor cell A cell involved in the formation of a monocyte (monopoiesis). http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract An epithelial cell of the tracheobronchial tree. http://purl.obolibrary.org/obo/CL_0002209 intermediate epitheliocyte http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell present in the trachea and bronchi; columnar in shape; generally lack cilia; immature forms of ciliated or secretory cells which have been formed from stem cells. http://purl.obolibrary.org/obo/CL_0002220 interstitial cell of pineal gland http://purl.obolibrary.org/obo/CL_0000710 neurecto-epithelial cell A cell located between the pinealocytes. http://purl.obolibrary.org/obo/CL_0002222 vertebrate lens cell http://purl.obolibrary.org/obo/CL_0000306 crystallin accumulating cell A cell comprising the transparent, biconvex body separating the posterior chamber and vitreous body, and constituting part of the refracting mechanism of the mammalian eye. http://purl.obolibrary.org/obo/CL_0002224 lens epithelial cell http://purl.obolibrary.org/obo/CL_0002222 vertebrate lens cell A cell of the cuboidal epithelium that covers the lens. The cells of the lens epithelium regulate most of the homeostatic functions of the lens. As ions, nutrients, and liquid enter the lens from the aqueous humor, Na+/K+ ATPase pumps in the lens epithelial cells pump ions out of the lens to maintain appropriate lens osmolarity and volume, with equatorially positioned lens epithelium cells contributing most to this current. The activity of the Na+/K+ ATPases keeps water and current flowing through the lens from the poles and exiting through the equatorial regions. The cells of the lens epithelium also serve as the progenitors for new lens fibers. It constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth. http://purl.obolibrary.org/obo/CL_0002240 marrow fibroblast http://purl.obolibrary.org/obo/CL_0010001 stromal cell of bone marrow A fibroblast in the bone marrow. http://purl.obolibrary.org/obo/CL_0002242 nucleate cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell containing at least one nucleus. http://purl.obolibrary.org/obo/CL_0002246 peripheral blood stem cell http://purl.obolibrary.org/obo/CL_0000080 circulating cell A hematopoeitic stem cell found in the blood. Normally found in very limited numbers in the peripheral circulation (less than 0.1% of all nucleated cells). http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the musculomembranous digestive tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal An epithelial cell of the lining of the esophagus. http://purl.obolibrary.org/obo/CL_0002262 endothelial cell of sinusoid http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that lines any of the venous cavities through which blood passes in various glands and organs such as the spleen and liver. http://purl.obolibrary.org/obo/CL_0002308 epithelial cell of skin gland http://purl.obolibrary.org/obo/CL_0002159 general ecto-epithelial cell An epithelial cell of a skin gland. http://purl.obolibrary.org/obo/CL_0002312 somatotroph http://purl.obolibrary.org/obo/CL_0000638 acidophil cell of pars distalis of adenohypophysis An acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/CL_0002319 neural cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell that is part of the nervous system. http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the supporting or framework tissue of the body, which includes adipose tissue, cartilage, and bone. In vertebrates, this cell arises chiefly from the embryonic mesoderm and, in cranial regions, from neural crest. http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) http://purl.obolibrary.org/obo/CL_0000000 cell A cell of the embryo. http://purl.obolibrary.org/obo/CL_0002328 bronchial epithelial cell http://purl.obolibrary.org/obo/CL_0002202 epithelial cell of tracheobronchial tree An epithelial cell of the bronchus. http://purl.obolibrary.org/obo/CL_0002333 neural crest derived adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte derived from a neural crest cell. http://purl.obolibrary.org/obo/CL_0002350 endocardial cell http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell An endothelial cell that lines the intracavitary lumen of the heart, separating the circulating blood from the underlying myocardium. This cell type releases a number of vasoactive substances including prostacyclin, nitrous oxide and endothelin. http://purl.obolibrary.org/obo/CL_0002352 gestational hematopoietic stem cell http://purl.obolibrary.org/obo/CL_0000037 hematopoietic stem cell A hematopoietic stem cell that exists during embryogenesis. http://purl.obolibrary.org/obo/CL_0002362 cerebellar granule cell precursor http://purl.obolibrary.org/obo/CL_0002319 neural cell A cell located in the outermost proliferative zone of the external germinal layer that can differentiate into astroglial cells and granule cells. This cell type is glial fibrillary acidic protein-positive and HNK1-positive. http://purl.obolibrary.org/obo/CL_0002363 keratocyte http://purl.obolibrary.org/obo/CL_0000005 neural crest derived fibroblast A keratocyte is a specialized fibroblast residing in the cornea stroma that has a flattened, dendritic morphology; located between the lamellae with a large flattened nucleus, and lengthy processes which communicate with neighboring cells. This corneal layer, representing about 85-90% of corneal thickness, is built up from highly regular collagenous lamellae and extracellular matrix components. Keratocytes play the major role in keeping it transparent, healing its wounds, and synthesizing its components. This cell type secretes collagen I, V, VI, and keratan sulfate. http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell http://purl.obolibrary.org/obo/CL_0002076 endo-epithelial cell An epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. http://purl.obolibrary.org/obo/CL_0002369 fungal spore http://purl.obolibrary.org/obo/CL_0000521 fungal cell A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. http://purl.obolibrary.org/obo/CL_0002372 myotube http://purl.obolibrary.org/obo/CL_0000737 striated muscle cell A transversely striated, multinucleated syncytial muscle cell, formed by the fusion of myoblasts during muscle development. http://purl.obolibrary.org/obo/CL_0002375 Schwann cell precursor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A multipotent progenitor cell that develops from a migratory neural crest cell. The schwann cell precursor is embedded among axons, with minimal extracellular space separating them from nerve cell membranes. This cell lacks a basal lamina, which distinguishes it from more mature Schwann cells. In rodents, cadherin-19 (Cdh19) serves as a specific marker for this developmental stage. http://purl.obolibrary.org/obo/CL_0002377 immature Schwann cell http://purl.obolibrary.org/obo/CL_0002573 Schwann cell A glial cell that develops from a Schwann cell precursor. The immature Schwann cell is embedded among neurons (axons) with minimal extracellular spaces separating them from nerve cell membranes and has a basal lamina. Cells can survive without an axon present. Immature Schwann cell can be found communally ensheathing large groups of axons. http://purl.obolibrary.org/obo/CL_0002397 CD14-positive, CD16-positive monocyte http://purl.obolibrary.org/obo/CL_0001054 CD14-positive monocyte A CD14-positive monocyte that is also CD16-positive and CCR2-negative. http://purl.obolibrary.org/obo/CL_0002421 nucleated reticulocyte http://purl.obolibrary.org/obo/CL_0002242 nucleate cell A reticulocyte that retains the nucleus and other organelles. Found in birds, fish, amphibians and reptiles. http://purl.obolibrary.org/obo/CL_0002453 oligodendrocyte precursor cell http://purl.obolibrary.org/obo/CL_0011026 progenitor cell A proliferative and migratory glial progenitor cell that derives from a neural stem cell and resides within the central nervous system. It possesses the capacity to differentiate into a committed oligodendrocyte progenitor (COP) through a well-defined series of maturation steps, ultimately giving rise to a myelinating oligodendrocyte (MOL). In mice and humans, it is characterized by the expression of specific molecular markers, including Pdgfra, Cspg4 (also known as NG2) and Olig2. http://purl.obolibrary.org/obo/CL_0002454 CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell CD4-negative, CD8-alpha-negative, CD11b-positive dendritic cell is a conventional dendritic cell that is CD11b-positive, CD4-negative, CD8-alpha-negative and is CD205-positive. http://purl.obolibrary.org/obo/CL_0002462 adipose dendritic cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A F4/80-negative dendritic cell located in adipose tissue. http://purl.obolibrary.org/obo/CL_0002463 SIRPa-positive adipose dendritic cell http://purl.obolibrary.org/obo/CL_0002462 adipose dendritic cell An adipose dendritic cell that is SIRPa-positive. http://purl.obolibrary.org/obo/CL_0002464 SIRPa-negative adipose dendritic cell http://purl.obolibrary.org/obo/CL_0002462 adipose dendritic cell An adipose dendritic cell that is SIRPa-negative. http://purl.obolibrary.org/obo/CL_0002465 CD11b-positive dendritic cell http://purl.obolibrary.org/obo/CL_0000990 conventional dendritic cell A conventional dendritic cell that expresses CD11b (ITGAM). http://purl.obolibrary.org/obo/CL_0002477 adipose macrophage http://purl.obolibrary.org/obo/CL_0000864 tissue-resident macrophage A macrophage located in adipose tissue that is CD45-positive, CD11c-positive, and SIRPa-positive. http://purl.obolibrary.org/obo/CL_0002478 F4/80-negative adipose macrophage http://purl.obolibrary.org/obo/CL_0002477 adipose macrophage An adipose macrophage that does not express F4/80but is MHC-II-positive. This cell type exhibits autofluorescence under typical flow cyometry conditions. http://purl.obolibrary.org/obo/CL_0002479 F4/80-positive adipose macrophage http://purl.obolibrary.org/obo/CL_0002477 adipose macrophage An adipose macrophage that does not express MHC-II but is F4/80-positive. http://purl.obolibrary.org/obo/CL_0002494 cardiocyte http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell located in the heart, including both muscle and non muscle cells. http://purl.obolibrary.org/obo/CL_0002503 adventitial cell http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A cell of the adventitial layer of ductal structures such as the uterer, defent duct, biliary duct, etc http://purl.obolibrary.org/obo/CL_0002521 subcutaneous adipocyte http://purl.obolibrary.org/obo/CL_0000136 adipocyte An adipocyte that is part of subcutaneous adipose tissue. http://purl.obolibrary.org/obo/CL_0002539 aortic smooth muscle cell http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the aorta. http://purl.obolibrary.org/obo/CL_0002540 mesenchymal stem cell of the bone marrow http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell A mesenchymal stem cell that is part of the bone marrow. http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the vein. http://purl.obolibrary.org/obo/CL_0002547 fibroblast of the aortic adventitia http://purl.obolibrary.org/obo/CL_1000306 fibroblast of tunica adventitia of artery A fibroblast of the aortic adventitia. http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A fibroblast that is part of the heart. http://purl.obolibrary.org/obo/CL_0002549 fibroblast of choroid plexus http://purl.obolibrary.org/obo/CL_0002319 neural cell A fibroblast that is part of the choroid plexus. http://purl.obolibrary.org/obo/CL_0002551 fibroblast of dermis http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of some dermis. http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of lung. http://purl.obolibrary.org/obo/CL_0002557 fibroblast of pulmonary artery http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of pulmonary artery. http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue http://purl.obolibrary.org/obo/CL_0000134 mesenchymal stem cell A mesenchymal stem cell of adipose tissue. http://purl.obolibrary.org/obo/CL_0002573 Schwann cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A glial cell that myelinates or ensheathes axons in the peripheral nervous system. http://purl.obolibrary.org/obo/CL_0002585 retinal blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell A blood vessel endothelial cell that is part of the retina. http://purl.obolibrary.org/obo/CL_0002589 smooth muscle cell of the brachiocephalic vasculature http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the bachiocephalic vasculature. http://purl.obolibrary.org/obo/CL_0002590 smooth muscle cell of the brain vasculature http://purl.obolibrary.org/obo/CL_0002319 neural cell A vascular associated smooth muscle cell of the brain vasculature. http://purl.obolibrary.org/obo/CL_0002591 smooth muscle cell of the pulmonary artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle of the pulmonary artery. http://purl.obolibrary.org/obo/CL_0002595 smooth muscle cell of the subclavian artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell A smooth muscle cell of the subclavian artery. http://purl.obolibrary.org/obo/CL_0002596 smooth muscle cell of the carotid artery http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell Smooth muscle cell of the carotid artery. http://purl.obolibrary.org/obo/CL_0002598 bronchial smooth muscle cell http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell Any smooth muscle cell that is part of some bronchus. http://purl.obolibrary.org/obo/CL_0002599 smooth muscle cell of the esophagus http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell of the esophagus. http://purl.obolibrary.org/obo/CL_0002600 smooth muscle cell of trachea http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell A smooth muscle cell of the trachea. http://purl.obolibrary.org/obo/CL_0002603 astrocyte of the cerebellum http://purl.obolibrary.org/obo/CL_2000005 brain macroglial cell An astrocyte of the cerebellum. http://purl.obolibrary.org/obo/CL_0002605 astrocyte of the cerebral cortex http://purl.obolibrary.org/obo/CL_1001579 cerebral cortex glial cell A transcriptomically distinct astrocyte that is found in the cerebral cortex. http://purl.obolibrary.org/obo/CL_0002606 astrocyte of the spinal cord http://purl.obolibrary.org/obo/CL_0000127 astrocyte An astrocyte of the spinal cord. http://purl.obolibrary.org/obo/CL_0002610 raphe nuclei neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the raphe nuclei. http://purl.obolibrary.org/obo/CL_0002612 neuron of the ventral spinal cord http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A neuron of the ventral spinal cord. http://purl.obolibrary.org/obo/CL_0002613 striatum neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A neuron of the striatum. http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast of skin. http://purl.obolibrary.org/obo/CL_0002632 epithelial cell of lower respiratory tract http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell Any epithelial cell that is part of some lower respiratory tract epithelium. http://purl.obolibrary.org/obo/CL_0002653 squamous endothelial cell http://purl.obolibrary.org/obo/CL_0000115 endothelial cell A squamous shaped endothelial cell. http://purl.obolibrary.org/obo/CL_0002657 glandular cell of esophagus http://purl.obolibrary.org/obo/CL_0002252 epithelial cell of esophagus A glandular epithelial cell of the esophagus. http://purl.obolibrary.org/obo/CL_0002663 myocardial endocrine cell of atrium http://purl.obolibrary.org/obo/CL_0002074 myocardial endocrine cell A myocardial endocrine cell that is part of the atrium. http://purl.obolibrary.org/obo/CL_0002664 cardioblast http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A stem cell that can give rise to multiple cell types (i.e. smooth muscle, endothelial) in the developing heart. http://purl.obolibrary.org/obo/CL_0002672 retinal progenitor cell http://purl.obolibrary.org/obo/CL_0000048 multi fate stem cell A multi-fate stem cell that can give rise to different retinal cell types including rod and cone cells. http://purl.obolibrary.org/obo/CL_0002673 tongue muscle cell http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber A skeletal muscle cell that is part of the tongue. http://purl.obolibrary.org/obo/CL_0002676 neural crest derived neuroblast http://purl.obolibrary.org/obo/CL_0000031 neuroblast (sensu Vertebrata) A neuroblast derived from a neural crest cell. http://purl.obolibrary.org/obo/CL_0005000 spinal cord interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron A CNS interneuron located in the spinal cord. http://purl.obolibrary.org/obo/CL_0005024 somatomotor neuron http://purl.obolibrary.org/obo/CL_0000108 cholinergic neuron A motor neuron that innervates a skeletal muscle. These motor neurons are all excitatory and cholinergic. http://purl.obolibrary.org/obo/CL_0007001 skeletogenic cell http://purl.obolibrary.org/obo/CL_0000000 cell Cell that has the potential to form a skeletal cell type (e.g. cells in periosteum, cells in marrow) and produce extracellular matrix (often mineralized) and skeletal tissue (often mineralized). http://purl.obolibrary.org/obo/CL_0007004 premigratory neural crest cell http://purl.obolibrary.org/obo/CL_0011012 neural crest cell Cell that is part of the neural crest region of the neuroepithelium, prior to migration. Note that not all premigratory neural crest cells may become migratory neural crest cells. http://purl.obolibrary.org/obo/CL_0007009 prechondroblast http://purl.obolibrary.org/obo/CL_0011026 progenitor cell Skeletogenic cell that has the potential to develop into a chondroblast; and arises from neural crest, meseosdermal and notochordal and connective tissue cells. http://purl.obolibrary.org/obo/CL_0008000 non-striated muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell Any muscle cell in which the fibers are not organised into sarcomeres. http://purl.obolibrary.org/obo/CL_0008001 hematopoietic precursor cell http://purl.obolibrary.org/obo/CL_0000988 hematopoietic cell Any hematopoietic cell that is a precursor of some other hematopoietic cell type. http://purl.obolibrary.org/obo/CL_0008002 skeletal muscle fiber http://purl.obolibrary.org/obo/CL_0002372 myotube A transversely striated, synctial cell of skeletal muscle. It is formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell http://purl.obolibrary.org/obo/CL_0000187 muscle cell A muscle cell that is part of some visceral muscle. http://purl.obolibrary.org/obo/CL_0008008 striated visceral muscle cell http://purl.obolibrary.org/obo/CL_0008007 visceral muscle cell A visceral muscle cell that is striated. Examples include the visceral muscle cells of arhtropods. http://purl.obolibrary.org/obo/CL_0008009 transversely striated visceral muscle cell http://purl.obolibrary.org/obo/CL_0008008 striated visceral muscle cell A visceral muscle that is transversely striated. Examples include the visceral muscle cells of arthropods. http://purl.obolibrary.org/obo/CL_0009000 sensory neuron of spinal nerve http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron A sensory neuron of the spinal nerve that senses body position and sends information about how much the muscle is stretched to the spinal cord. http://purl.obolibrary.org/obo/CL_0009001 compound eye retinal cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Any cell in the compound eye, a light sensing organ composed of ommatidia. http://purl.obolibrary.org/obo/CL_0009004 retinal cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any cell in the retina, the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/CL_0010001 stromal cell of bone marrow http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell A stromal cell that is part_of a bone marrow. http://purl.obolibrary.org/obo/CL_0010004 mononuclear cell of bone marrow http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell A mononuclear cell that is part_of a bone marrow. http://purl.obolibrary.org/obo/CL_0010006 cardiac blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell Any blood vessel endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/CL_0010007 His-Purkinje system cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any cell that is part of some His-Purkinje system. http://purl.obolibrary.org/obo/CL_0010008 cardiac endothelial cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any endothelial cell that is part of some heart. http://purl.obolibrary.org/obo/CL_0010009 camera-type eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0009004 retinal cell Any photoreceptor cell that is part of some camera-type eye. http://purl.obolibrary.org/obo/CL_0010010 cerebellar stellate cell http://purl.obolibrary.org/obo/CL_0000691 stellate interneuron A GABAergic interneuron that is located in the molecular layer of the cerebellum. This cell receives excitatory inputs primarily from parallel fibers and plays a crucial role in feed-forward inhibition by suppressing the activity of Purkinje cells and modulating the output of the cerebellar cortex. The stellate cell is part of the local circuitry that contributes to the fine-tuning of motor coordination and a regulator of cerebellar blood flow via neurovascular coupling. http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron whose soma is located in the cerebral cortex. http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A CNS neuron of the cerebral cortex. http://purl.obolibrary.org/obo/CL_0010020 cardiac glial cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any glial cell that is part of some heart. http://purl.obolibrary.org/obo/CL_0010021 cardiac myoblast http://purl.obolibrary.org/obo/CL_0000056 myoblast Any myoblast that develops into some cardiac muscle cell. http://purl.obolibrary.org/obo/CL_0010022 cardiac neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron that has its soma in the heart. http://purl.obolibrary.org/obo/CL_0011001 spinal cord motor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron An interneuron that uses GABA as a vesicular neurotransmitter. These interneurons are inhibitory http://purl.obolibrary.org/obo/CL_0011006 Lugaro cell http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron A cerebellar interneuron characterized by a spindle-shaped or triangular soma, parasagittally oriented and located at the border between the granular layer and the Purkinje cell layer. The Lugaro cell extends dendrites predominantly in the parasagittal plane, forming synaptic interactions with basket, stellate, and Golgi cells. Its axonal projections extend upward into the molecular layer, where they form a parasagittal plexus and emit long transverse collaterals that run parallel to the long axis of the cerebellar folia. The Lugaro cell is capable of co-releasing GABA and glycine, as evidenced by the expression of glutamate decarboxylase (GAD65/67) and the glycine transporter GlyT2. http://purl.obolibrary.org/obo/CL_0011111 hypothalamic gonadotropin-releasing hormone neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain a specialized neuroendocrine cell that synthesizes and secretes GnRH decapeptide, a key regulator of reproductive function. It originates from the olfactory placode during embryonic development and migrates into the forebrain where it localises predominantly in the hypothalamus and in humans, in extrahypothalamic regions like the basal ganglia (Skrapits et al., 2021). This cell regulates reproduction by secreting GnRH into the pituitary portal vessels to induce the release of gonadotropins into the general circulation. It expresses receptor subunits required for AMPA, NMDA, and kainate receptor signaling and may use glutamate as a neurotransmitter in recurrent collateral innervation. http://purl.obolibrary.org/obo/CL_0012000 astrocyte of the forebrain http://purl.obolibrary.org/obo/CL_2000005 brain macroglial cell An astrocyte of the forebrain. http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A CNS neuron of the forebrain. http://purl.obolibrary.org/obo/CL_0013000 forebrain radial glial cell http://purl.obolibrary.org/obo/CL_0000681 radial glial cell Any radial glial cell that is part of some forebrain. http://purl.obolibrary.org/obo/CL_1000042 forebrain neuroblast http://purl.obolibrary.org/obo/CL_0002319 neural cell Any neuroblast (sensu Vertebrata) that is part of some forebrain. http://purl.obolibrary.org/obo/CL_1000073 spinal cord radial glial cell http://purl.obolibrary.org/obo/CL_0000681 radial glial cell Any radial glial cell that is part of some spinal cord. http://purl.obolibrary.org/obo/CL_1000223 pulmonary neuroendocrine cell http://purl.obolibrary.org/obo/CL_1000272 lung secretory cell A neuroendocrine cell that is part of respiratory epithelium of the lung and is involved in the sensory detection of environmental stimuli, including hypoxia, nicotine and air pressure. Ultrastructurally, this cell type is characterized by the presence of cytoplasmic dense core granules, which are considered the storage sites of amine and peptide hormones. Pulmonary neuroendocrine cells are innervated and appear as solitary cells or as clustered masses, localized at airway bifurcation sites, called neuroepithelial bodies that can release serotonin in response to hypoxia and interact with sensory nerve terminals. Pulmonary neuroendocrine cells also function as reserve stem cells that repair the surrounding epithelium after injury. http://purl.obolibrary.org/obo/CL_1000272 lung secretory cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any secretory cell that is part of some lung. http://purl.obolibrary.org/obo/CL_1000274 trophectodermal cell http://purl.obolibrary.org/obo/CL_0000349 extraembryonic cell An extraembryonic cell that is part of the trophectoderm, representing the first lineage to differentiate in the embryo. This cell is crucial for implantation into the uterine wall and differentiates into trophoblast cells, which contribute to placenta formation and facilitate maternal-fetal nutrient and signal exchange. http://purl.obolibrary.org/obo/CL_1000298 mesothelial cell of dura mater http://purl.obolibrary.org/obo/CL_0002319 neural cell A mesothelial cell that is part of the dura mater. http://purl.obolibrary.org/obo/CL_1000303 fibroblast of areolar connective tissue http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the areolar connective tissue. http://purl.obolibrary.org/obo/CL_1000306 fibroblast of tunica adventitia of artery http://purl.obolibrary.org/obo/CL_4052030 adventitial fibroblast A fibroblast that is part of the tunica adventitia of artery. http://purl.obolibrary.org/obo/CL_1000307 fibroblast of dense regular elastic tissue http://purl.obolibrary.org/obo/CL_0000057 fibroblast A fibroblast that is part of the dense regular elastic tissue. http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte http://purl.obolibrary.org/obo/CL_0002494 cardiocyte An adipocyte that is part of the epicardial fat. http://purl.obolibrary.org/obo/CL_1000310 adipocyte of epicardial fat of right ventricle http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte An adipocyte that is part of the epicardial fat of right ventricle. http://purl.obolibrary.org/obo/CL_1000311 adipocyte of epicardial fat of left ventricle http://purl.obolibrary.org/obo/CL_1000309 epicardial adipocyte An adipocyte that is part of the epicardial fat of left ventricle. http://purl.obolibrary.org/obo/CL_1000330 serous cell of epithelium of trachea http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of trachea. http://purl.obolibrary.org/obo/CL_1000331 serous cell of epithelium of bronchus http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell A serous secreting cell that is part of the epithelium of bronchus. http://purl.obolibrary.org/obo/CL_1000361 transitional myocyte of interatrial septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A transitional myocyte that is part of the interatrial septum. http://purl.obolibrary.org/obo/CL_1000362 transitional myocyte of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A transitional myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/CL_1000376 Purkinje myocyte of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A Purkinje myocyte that is part of the interventricular septum. http://purl.obolibrary.org/obo/CL_1000409 myocyte of sinoatrial node http://purl.obolibrary.org/obo/CL_0008009 transversely striated visceral muscle cell A muscle cell that is part of the sinoatrial node. http://purl.obolibrary.org/obo/CL_1000410 myocyte of atrioventricular node http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A muscle cell that is part of the atrioventricular node. http://purl.obolibrary.org/obo/CL_1000412 endothelial cell of arteriole http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the arteriole. http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell A blood vessel endothelial cell that is part of an arterial endothelium. http://purl.obolibrary.org/obo/CL_1000414 endothelial cell of venule http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell An endothelial cell that is part of the venule. http://purl.obolibrary.org/obo/CL_1000428 stem cell of epidermis http://purl.obolibrary.org/obo/CL_0000723 somatic stem cell A somatic stem cell that is part of the epidermis. http://purl.obolibrary.org/obo/CL_1000443 ciliary muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the ciliary body. http://purl.obolibrary.org/obo/CL_1000444 mesothelial cell of anterior chamber of eye http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the anterior chamber of eyeball. http://purl.obolibrary.org/obo/CL_1000456 mesothelial cell of parietal peritoneum http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum A mesothelial cell that is part of the parietal peritoneum. http://purl.obolibrary.org/obo/CL_1000457 mesothelial cell of visceral peritoneum http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum A mesothelial cell that is part of the visceral peritoneum. http://purl.obolibrary.org/obo/CL_1000465 chromaffin cell of ovary http://purl.obolibrary.org/obo/CL_0000166 chromaffin cell A chromaffin cell that is part of the ovary. http://purl.obolibrary.org/obo/CL_1000466 chromaffin cell of right ovary http://purl.obolibrary.org/obo/CL_1000465 chromaffin cell of ovary A chromaffin cell that is part of the right ovary. http://purl.obolibrary.org/obo/CL_1000467 chromaffin cell of left ovary http://purl.obolibrary.org/obo/CL_1000465 chromaffin cell of ovary A chromaffin cell that is part of the left ovary. http://purl.obolibrary.org/obo/CL_1000478 transitional myocyte of sinoatrial node http://purl.obolibrary.org/obo/CL_1000409 myocyte of sinoatrial node A transitional myocyte that is part of the sinoatrial node. http://purl.obolibrary.org/obo/CL_1000479 Purkinje myocyte of atrioventricular node http://purl.obolibrary.org/obo/CL_1000410 myocyte of atrioventricular node A Purkinje myocyte that is part of the atrioventricular node. http://purl.obolibrary.org/obo/CL_1000482 myocardial endocrine cell of interventricular septum http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell A myocardial endocrine cell that is part of the interventricular septum. http://purl.obolibrary.org/obo/CL_1000490 mesothelial cell of peritoneum http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the peritoneum. http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura http://purl.obolibrary.org/obo/CL_0000077 mesothelial cell A mesothelial cell that is part of the pleura. http://purl.obolibrary.org/obo/CL_1000492 mesothelial cell of parietal pleura http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura A mesothelial cell that is part of the parietal pleura. http://purl.obolibrary.org/obo/CL_1000493 mesothelial cell of visceral pleura http://purl.obolibrary.org/obo/CL_1000491 mesothelial cell of pleura A mesothelial cell that is part of the visceral pleura. http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron An inhibitory, GABAergic projection neuron in the striatum that integrates glutamatergic signals arising from the cerebral cortex and thalamus. http://purl.obolibrary.org/obo/CL_1001509 glycinergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron The neurons that utilize glycine as a neurotransmitter. http://purl.obolibrary.org/obo/CL_1001567 lung endothelial cell http://purl.obolibrary.org/obo/CL_0002139 endothelial cell of vascular tree Any endothelial cell of vascular tree that is part of some lung. http://purl.obolibrary.org/obo/CL_1001568 pulmonary artery endothelial cell http://purl.obolibrary.org/obo/CL_1000413 endothelial cell of artery Any endothelial cell of vascular tree that is part of some pulmonary artery. http://purl.obolibrary.org/obo/CL_1001576 oral mucosa squamous cell http://purl.obolibrary.org/obo/CL_0002251 epithelial cell of alimentary canal Squamous cell of oral epithelium. http://purl.obolibrary.org/obo/CL_1001579 cerebral cortex glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell Glial cell of cerebral cortex. http://purl.obolibrary.org/obo/CL_1001581 lateral ventricle glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell Glial cell of lateral ventricle. http://purl.obolibrary.org/obo/CL_1001582 lateral ventricle neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain Neuron of lateral ventricle. http://purl.obolibrary.org/obo/CL_1001602 cerebral cortex endothelial cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A distinct endothelial cell forming the walls of the capillaries within the cerebral cortex. http://purl.obolibrary.org/obo/CL_1001603 lung macrophage http://purl.obolibrary.org/obo/CL_0000235 macrophage Circulating macrophages and tissue macrophages (alveolar macrophages) of lung. http://purl.obolibrary.org/obo/CL_1001609 muscle fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Fibroblast from muscle organ. http://purl.obolibrary.org/obo/CL_1001610 bone marrow hematopoietic cell http://purl.obolibrary.org/obo/CL_0002092 bone marrow cell Hematopoietic cells resident in the bone marrow. Include: hematopoietic stem cells (lymphoid stem cells and myeloid stem cells) and the precursor cells for thrombocytes, erythrocytes, basophils, neutrophils, eosinophils, monocytes and lymphocytes. http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Neuron of the cerebellum. http://purl.obolibrary.org/obo/CL_2000001 peripheral blood mononuclear cell http://purl.obolibrary.org/obo/CL_0000842 mononuclear leukocyte A leukocyte with a single non-segmented nucleus in the mature form found in the circulatory pool of blood. http://purl.obolibrary.org/obo/CL_2000004 pituitary gland cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any cell that is part of a pituitary gland. http://purl.obolibrary.org/obo/CL_2000005 brain macroglial cell http://purl.obolibrary.org/obo/CL_0000126 macroglial cell Any macroglial cell that is part of a brain. http://purl.obolibrary.org/obo/UBERON_0000007 pituitary gland http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands [GO]. An endocrine gland located ventral to the diencephalon and derived from mixed neuroectodermal and non neuroectodermal origin [ZFIN]. http://purl.obolibrary.org/obo/UBERON_0000010 peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A major division of the nervous system that contains nerves which connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ Any portion of the organ that covers that body and consists of a layer of epidermis and a layer of dermis. http://purl.obolibrary.org/obo/UBERON_0000020 sense organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is capable of transducing sensory stimulus to the nervous system. http://purl.obolibrary.org/obo/UBERON_0000065 respiratory tract http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway Anatomical structure that is part of the respiratory system. In mammals consists of upper and lower tracts. http://purl.obolibrary.org/obo/UBERON_0000165 mouth http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The proximal portion of the digestive tract, containing the oral cavity and bounded by the oral opening. In vertebrates, this extends to the pharynx and includes gums, lips, tongue and parts of the palate. Typically also includes the teeth, except where these occur elsewhere (e.g. pharyngeal jaws) or protrude from the mouth (tusks). http://purl.obolibrary.org/obo/UBERON_0000167 oral cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity at the start of the digestive tract that that is enclosed by the mouth. The boundaries and contents vary depending on the species. In vertebrates, the boundaries are the oral opening, the cheeks, the palate and (if present) the palatoglossal arch - if this is not present then the mouth and pharynx form the oropharyngeal cavity. The buccal cavity contains the teeth, tongue and palate (when present). http://purl.obolibrary.org/obo/UBERON_0000178 blood http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid A fluid that is composed of blood plasma and erythrocytes. http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Multicellular, connected anatomical structure that has multiple organs as parts and whose parts work together to achieve some shared function. http://purl.obolibrary.org/obo/UBERON_0000948 heart http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ. http://purl.obolibrary.org/obo/UBERON_0000949 endocrine system http://purl.obolibrary.org/obo/UBERON_0015204 glandular system Anatomical system that consists of the glands and parts of glands that produce endocrine secretions and help to integrate and control bodily metabolic activity. http://purl.obolibrary.org/obo/UBERON_0000955 brain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The brain is the center of the nervous system in all vertebrate, and most invertebrate, animals. Some primitive animals such as jellyfish and starfish have a decentralized nervous system without a brain, while sponges lack any nervous system at all. In vertebrates, the brain is located in the head, protected by the skull and close to the primary sensory apparatus of vision, hearing, balance, taste, and smell[WP]. http://purl.obolibrary.org/obo/UBERON_0000964 cornea http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The transparent anterior portion of the fibrous coat of the eye that serves as the chief refractory structure. http://purl.obolibrary.org/obo/UBERON_0000965 lens of camera-type eye http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure A transparent and refractive lens located posterior to the iris. The lens of camera-type eye refracts light to be focused on the retina. http://purl.obolibrary.org/obo/UBERON_0000966 retina http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/UBERON_0000970 eye http://purl.obolibrary.org/obo/UBERON_0000020 sense organ An organ that detects light. http://purl.obolibrary.org/obo/UBERON_0000977 pleura http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane The invaginated serous membrane that surrounds the lungs (the visceral portion) and lines the walls of the pleural cavity (parietal portion). http://purl.obolibrary.org/obo/UBERON_0000990 reproductive system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that has as its parts the organs concerned with reproduction. http://purl.obolibrary.org/obo/UBERON_0000992 ovary http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ The gonad of a female organism which contains germ cells. http://purl.obolibrary.org/obo/UBERON_0001004 respiratory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Functional system which consists of structures involved in respiration. http://purl.obolibrary.org/obo/UBERON_0001016 nervous system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The nervous system is an organ system containing predominantly neuron and glial cells. In bilaterally symmetrical organism, it is arranged in a network of tree-like structures connected to a central body. The main functions of the nervous system are to regulate and control body functions, and to receive sensory input, process this information, and generate behavior [CUMBO]. http://purl.obolibrary.org/obo/UBERON_0001017 central nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system Anatomical system that overlaps the nervous system and is responsible for receiving and processing sensory information. http://purl.obolibrary.org/obo/UBERON_0001043 esophagus http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Tube that connects the pharynx to the stomach. In mammals, the oesophagus connects the buccal cavity with the stomach. The stratified squamous non-keratinised epithelium lining the buccal cavity is continued through the pharynx down into the oesophagus. The lowest part of the oesophagus (ca. 2 cm) is lined with gastric mucosa and covered by peritoneum. The main body of the oesophagus is lined with small, simple mucous glands. Each gland opens into the lumen by a long duct which pierces the muscularis mucosae (Wilson and Washington, 1989). A sphincter is situated at the point where the oesophagus enters the stomach to prevent gastro-oesophageal reflux, i.e. to prevent acidic gastric contents from reaching stratified epithelia of the oesophagus, where they can cause inflammation and irritation (Wilson and Washington, 1989; Brown et al., 1993). http://purl.obolibrary.org/obo/UBERON_0001103 diaphragm http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle A thin musculomebranous barrier that separates the abdominal and thoracic cavities. Often used for breathing control. http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue Muscle tissue that consists primarily of skeletal muscle fibers. http://purl.obolibrary.org/obo/UBERON_0001558 lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract The segment of the respiratory tract that starts proximally with the trachea and includes all distal structures including the lungs[WP,modified]. http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An epithelial tube or tree of tibes that transports blood away from the heart[modified from AEO definition]. http://purl.obolibrary.org/obo/UBERON_0001650 hypoglossal nerve http://purl.obolibrary.org/obo/UBERON_0001785 cranial nerve Cranial nerve that innervates the muscles of the tongue. http://purl.obolibrary.org/obo/UBERON_0001708 jaw skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which includes upper and lower jaw skeletons. http://purl.obolibrary.org/obo/UBERON_0001723 tongue http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A muscular organ in the floor of the mouth. http://purl.obolibrary.org/obo/UBERON_0001737 larynx http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract A continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/UBERON_0001739 laryngeal cartilage http://purl.obolibrary.org/obo/UBERON_0011004 pharyngeal arch cartilage The cartilaginous structures that support the larynx. http://purl.obolibrary.org/obo/UBERON_0001759 vagus nerve http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Cranial nerve that branches into the lateral (to body sense organs) and the intestino-accessorial (to the skin, muscles of shoulder, hyoid, larynx, gut, lungs, and heart). http://purl.obolibrary.org/obo/UBERON_0001776 optic choroid http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye Vascular layer containing connective tissue, of the eye lying between the retina and the sclera. The choroid provides oxygen and nourishment to the outer layers of the retina. Along with the ciliary body and iris, the choroid forms the uveal tract[WP]. http://purl.obolibrary.org/obo/UBERON_0001833 lip http://purl.obolibrary.org/obo/UBERON_0003102 surface structure One of the two fleshy folds which surround the opening of the mouth. http://purl.obolibrary.org/obo/UBERON_0001982 capillary http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel Any of the smallest blood vessels connecting arterioles with venules. http://purl.obolibrary.org/obo/UBERON_0002012 pulmonary artery http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart An artery that carries deoxygenated blood from heart to the lungs. They are the only arteries (other than umbilical arteries in the fetus) that carry deoxygenated blood.. http://purl.obolibrary.org/obo/UBERON_0002048 lung http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Respiration organ that develops as an outpocketing of the esophagus. http://purl.obolibrary.org/obo/UBERON_0002165 endocardium http://purl.obolibrary.org/obo/UBERON_0005983 heart layer The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers[GO]. http://purl.obolibrary.org/obo/UBERON_0002185 bronchus http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The upper conducting airways of the lung; these airways arise from the terminus of the trachea. http://purl.obolibrary.org/obo/UBERON_0002204 musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the muscular and skeletal systems. http://purl.obolibrary.org/obo/UBERON_0002240 spinal cord http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Part of the central nervous system located in the vertebral canal continuous with and caudal to the brain; demarcated from brain by plane of foramen magnum. It is composed of an inner core of gray matter in which nerve cells predominate, and an outer layer of white matter in which myelinated nerve fibers predominate, and surrounds the central canal. (CUMBO). http://purl.obolibrary.org/obo/UBERON_0002298 brainstem http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Stalk-like part of the brain that includes amongst its parts the medulla oblongata of the hindbrain and the tegmentum of the midbrain[ZFA,MP,generalized]. http://purl.obolibrary.org/obo/UBERON_0002330 exocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical system that consists of the glands and parts of glands that produce exocrine secretions and help to integrate and control bodily metabolic activity. Exocrine glands are glands that secrete their products (hormones) into ducts (duct glands). They are the counterparts to endocrine glands, which secrete their products (hormones) directly into the bloodstream (ductless glands) or release hormones (paracrines) that affect only target cells nearby the release site. [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0002351 sinoatrial node http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart The part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node[GO]. Subdivision of conducting system of heart at the junction of the right atrium and the superior vena cava, around the sinoatrial nodal branch of right coronary artery and is continuous with the internodal tract[FMA]. http://purl.obolibrary.org/obo/UBERON_0002358 peritoneum http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that lines the peritoneal cavity[VHOG,modified]. http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Endocrine glands are glands of the endocrine system that secrete their products directly into the circulatory system rather than through a duct.[WP, modified]. http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Tissue with cells that deposit non-polarized extracellular matrix including connective tissue fibers and ground substance. http://purl.obolibrary.org/obo/UBERON_0002405 immune system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system Anatomical system that protects the body from foreign substances, cells, and tissues by producing the immune response and that includes especially the thymus, spleen, lymphoid tissue, lymphocytes including the B cells and T cells, and antibodies. http://purl.obolibrary.org/obo/UBERON_0002407 pericardium http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The combination of pericardial sac (a double-walled sac containing the heart and the roots of the great vessels) plus fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0002410 autonomic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands[GO]. http://purl.obolibrary.org/obo/UBERON_0002416 integumental system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Connected anatomical system that forms a barrier between an animal and its environment. In vertebrates, the integumental system consists of the epidermis, dermis plus associated glands and adnexa such as hair and scales. In invertebrates, the integumental system may include cuticle. http://purl.obolibrary.org/obo/UBERON_0003126 trachea http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube The trachea is the portion of the airway that attaches to the bronchi as it branches [GO:dph]. http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An organ involved in reproduction. http://purl.obolibrary.org/obo/UBERON_0003134 female reproductive organ http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ A female organ involved in reproduction. http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An internal pocketing of pharyngeal endoderm that contacts a region of ectoderm (a pharyngeal cleft) and interdigitates in the anterior and posterior directions with the pharyngeal arches. http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Anatomical system that has as its parts the heart and blood vessels. http://purl.obolibrary.org/obo/UBERON_0005057 immune organ http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that is part of a immune system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0006562 pharynx http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The pharynx is the part of the digestive system immediately posterior to the mouth[GO]. http://purl.obolibrary.org/obo/UBERON_0010011 collection of basal ganglia http://purl.obolibrary.org/obo/UBERON_0010009 aggregate regional part of brain Subcortical masses of gray matter in the forebrain and midbrain that are richly interconnected and so viewed as a functional system. The nuclei usually included are the caudate nucleus (caudoputamen in rodents), putamen, globus pallidus, substantia nigra (pars compacta and pars reticulata) and the subthalamic nucleus. Some also include the nucleus accumbens and ventral pallidum. http://purl.obolibrary.org/obo/UBERON_0035549 vasculature of integument http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the circulatory system that lies within the subcutaneous tissue layers close to the surface of the skin. http://purl.obolibrary.org/obo/UBERON_0035551 deep vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the circulatory system that lies deep beneath the subcutaneous tissue layers away from the surface of the skin. http://purl.obolibrary.org/obo/UBERON_0035552 deep vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A blood vessel carrying deoxygenated blood far beneath the skin usually accompanying an artery. http://purl.obolibrary.org/obo/UBERON_0035642 laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve Any nerve that innervates the larynx. http://purl.obolibrary.org/obo/GO_0110110 positive regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_0110111 negative regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_0140231 anterograde axonal transport of neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0099641 anterograde axonal protein transport The directed movement of a neurotransmitter receptor complex along microtubules from the cell body toward the cell periphery in nerve cell axons. http://purl.obolibrary.org/obo/GO_0150105 protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction A process in which a protein is transported to, or maintained, in a location within a cell-cell junction. http://purl.obolibrary.org/obo/CHEBI_2762 antimycin A http://purl.obolibrary.org/obo/CHEBI_33853 phenols A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. http://purl.obolibrary.org/obo/GO_0120305 regulation of pigmentation http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism. http://purl.obolibrary.org/obo/PHIPO_0001287 normal growth on tolnaftate http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to tolnaftate (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001288 resistance to tolnaftate http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tolnaftate. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001289 sensitive to tolnaftate http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tolnaftate. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001290 normal growth on azoxystrobin http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to azoxystrobin (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001291 resistance to fenpicoxamid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fenpicoxamid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001292 sensitive to fenpicoxamid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpicoxamid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001293 normal growth on fenpicoxamid http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to fenpicoxamid (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/CL_4042013 Lamp5 Lhx6 neuron http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron A transcriptomically distinct GABAergic interneuron marked by Lamp5 and Lhx6 expression, derived from the Medial Ganglionic Eminence (MGE), and located in the pallium. http://purl.obolibrary.org/obo/CL_4307052 Astro-OLF NN_1 Stk32a astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301596 Astro-OLF NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Prss23 (Mmus), Stk32a (Mmus). It is distinguished from other Astro-OLF NN_1 cells by expression of Stk32a. These cells are located in the Olfactory areas, brain , in or close to the regions: olfactory nerve layer of main olfactory bulb, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5232 Astro-OLF NN_1. http://purl.obolibrary.org/obo/CL_4307035 Astro-NT NN_2 Sez6l astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Otx2 (Mmus), Unc13c (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Sez6l, Unc13c. These cells are located in the Thalamus , in or close to the regions: Posterior complex of the thalamus, Ventral posteromedial nucleus of the thalamus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5215 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:326 OPC NN. http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4072102 Purkinje layer interneuron A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Rgs6 (Mmus), Slc6a5 (Mmus), Shisa9 (Mmus), Zic1 (Mmus), Bmp6 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:309 CB PLI Gly-Gaba. http://purl.obolibrary.org/obo/CL_4301584 CB Granule Glut_1 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Lmx1a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1154 CB Granule Glut_1. http://purl.obolibrary.org/obo/CL_4301575 Lugaro cell (Mmus) http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Lugaro cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pthlh (Mmus), Tfap2b (Mmus), Rspo2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1145 CB PLI Gly-Gaba_2. http://purl.obolibrary.org/obo/CL_4307095 COP NN_1 Bmp4 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Bmp4 (Mmus), Mob3b (Mmus). It is distinguished from other COP NN_1 cells by expression of Bmp4, Mob3b. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5275 COP NN_1. http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron A cerebellar neuron of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:28 CB GABA. http://purl.obolibrary.org/obo/CHEBI_100147 nalidixic acid http://purl.obolibrary.org/obo/CHEBI_86324 quinolone antibiotic A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species. http://purl.obolibrary.org/obo/CHEBI_10022 deoxynivalenol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A trichothecene mycotoxin produced by Fusarium to which wheat, barley, maize (corn) and their products are susceptible to contamination. http://purl.obolibrary.org/obo/CHEBI_10023 voriconazole http://purl.obolibrary.org/obo/CHEBI_87101 triazole antifungal drug A triazole-based antifungal agent used for the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by Scedosporium apiospermum and Fusarium spp. It is an inhibitor of cytochrome P450 2C9 (CYP2C9) and CYP3A4. http://purl.obolibrary.org/obo/CHEBI_100241 ciprofloxacin http://purl.obolibrary.org/obo/CHEBI_51454 cyclopropanes A quinolone that is quinolin-4(1H)-one bearing cyclopropyl, carboxylic acid, fluoro and piperazin-1-yl substituents at positions 1, 3, 6 and 7, respectively. http://purl.obolibrary.org/obo/CHEBI_100246 norfloxacin http://purl.obolibrary.org/obo/CHEBI_87211 fluoroquinolone antibiotic A quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase. http://purl.obolibrary.org/obo/CHEBI_102484 sulfisoxazole http://purl.obolibrary.org/obo/CHEBI_87228 sulfonamide antibiotic A sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of gram-negative and gram-positive organisms. http://purl.obolibrary.org/obo/CHEBI_131604 Mycoplasma genitalium metabolite http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. http://purl.obolibrary.org/obo/CHEBI_13248 anilide http://purl.obolibrary.org/obo/CHEBI_62733 aromatic amide Any aromatic amide obtained by acylation of aniline. http://purl.obolibrary.org/obo/CHEBI_15705 L-alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid Any α-amino acid having L-configuration at the α-carbon. http://purl.obolibrary.org/obo/CHEBI_16670 peptide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from α-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc. http://purl.obolibrary.org/obo/CHEBI_17087 ketone http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H). http://purl.obolibrary.org/obo/CHEBI_17154 nicotinamide http://purl.obolibrary.org/obo/CHEBI_25529 pyridinecarboxamide A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. http://purl.obolibrary.org/obo/CHEBI_17568 uracil http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. http://purl.obolibrary.org/obo/CHEBI_17925 alpha-D-glucose http://purl.obolibrary.org/obo/CHEBI_4167 D-glucopyranose D-Glucopyranose having α-configuration at the anomeric centre. http://purl.obolibrary.org/obo/CHEBI_18379 nitrile http://purl.obolibrary.org/obo/CHEBI_23424 cyanides A compound having the structure RC≡N; thus a C-substituted derivative of hydrocyanic acid, HC≡N. In systematic nomenclature, the suffix nitrile denotes the triply bound ≡N atom, not the carbon atom attached to it. http://purl.obolibrary.org/obo/CHEBI_18946 delta-lactone http://purl.obolibrary.org/obo/CHEBI_25000 lactone A lactone having a six-membered lactone ring. http://purl.obolibrary.org/obo/CHEBI_21731 N-glycosyl compound http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond. http://purl.obolibrary.org/obo/CHEBI_22160 acetamides http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide Compounds with the general formula RNHC(=O)CH3. http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. http://purl.obolibrary.org/obo/CHEBI_22586 antioxidant http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. http://purl.obolibrary.org/obo/CHEBI_22587 antiviral agent http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent A substance that destroys or inhibits replication of viruses. http://purl.obolibrary.org/obo/CHEBI_22712 benzenes http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_22723 benzoic acids http://purl.obolibrary.org/obo/CHEBI_33859 aromatic carboxylic acid Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group. http://purl.obolibrary.org/obo/CHEBI_22888 biphenyls http://purl.obolibrary.org/obo/CHEBI_64459 biaryl Benzenoid aromatic compounds containing two phenyl or substituted-phenyl groups which are joined together by a single bond. http://purl.obolibrary.org/obo/CHEBI_23003 carbamate ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any ester of carbamic acid or its N-substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_23018 EC 4.2.1.1 (carbonic anhydrase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76907 EC 4.2.1.* (hydro-lyases) inhibitor An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of carbonic anhydrase (EC 4.2.1.1). Such compounds reduce the secretion of H+ ions by the proximal kidney tubule. http://purl.obolibrary.org/obo/CHEBI_23697 dichlorobenzene http://purl.obolibrary.org/obo/CHEBI_23132 chlorobenzenes Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions. http://purl.obolibrary.org/obo/CHEBI_24780 imidazoles http://purl.obolibrary.org/obo/CHEBI_23677 diazole A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. http://purl.obolibrary.org/obo/CHEBI_24828 indoles http://purl.obolibrary.org/obo/CHEBI_22728 benzopyrrole Any compound containing an indole skeleton. http://purl.obolibrary.org/obo/CHEBI_24995 lactam http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. http://purl.obolibrary.org/obo/CHEBI_25106 macrolide http://purl.obolibrary.org/obo/CHEBI_26188 polyketide A macrocyclic lactone with a ring of twelve or more members derived from a polyketide. http://purl.obolibrary.org/obo/CHEBI_25212 metabolite http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. http://purl.obolibrary.org/obo/CHEBI_25248 methyl ester http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol. http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid An oxoacid containing a single carboxy group. http://purl.obolibrary.org/obo/CHEBI_25477 naphthalenes http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings. http://purl.obolibrary.org/obo/CHEBI_25529 pyridinecarboxamide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A member of the class of pyridines that is a substituted pyridine in which at least one of the substituents is a carboxamide or N-substituted caraboxamide group. http://purl.obolibrary.org/obo/CHEBI_25697 organic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation Any organic ion with a net positive charge. http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol http://purl.obolibrary.org/obo/CHEBI_33853 phenols Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_26273 proline derivative http://purl.obolibrary.org/obo/CHEBI_83821 amino-acid derivative An amino acid derivative resulting from reaction of proline at the amino group or the carboxy group, or from the replacement of any hydrogen of proline by a heteroatom. The definition normally excludes peptides containing proline residues. http://purl.obolibrary.org/obo/CHEBI_26420 pyridinemonocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33859 aromatic carboxylic acid A monocarboxylic acid in which the carboxy group is attached to a pyridine (or substituted pyridine) ring. http://purl.obolibrary.org/obo/CHEBI_26421 pyridines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_26512 quinolinemonocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33859 aromatic carboxylic acid Any aromatic carboxylic acid that contains a quinoline moiety that is substituted by one carboxy substituent. http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_26873 terpenoid Any terpenoid derived from a sesquiterpene. The term includes compounds in which the C15 skeleton of the parent sesquiterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). http://purl.obolibrary.org/obo/CHEBI_26878 tertiary alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A tertiary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it. http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound http://purl.obolibrary.org/obo/CHEBI_36688 heterotricyclic compound An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms. http://purl.obolibrary.org/obo/CHEBI_27822 2-aminobenzimidazole http://purl.obolibrary.org/obo/CHEBI_22715 benzimidazoles A member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group. http://purl.obolibrary.org/obo/CHEBI_29347 monocarboxylic acid amide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A carboxamide derived from a monocarboxylic acid. http://purl.obolibrary.org/obo/CHEBI_32877 primary amine http://purl.obolibrary.org/obo/CHEBI_50994 primary amino compound A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group. http://purl.obolibrary.org/obo/CHEBI_32955 epoxide http://purl.obolibrary.org/obo/CHEBI_37407 cyclic ether Any cyclic ether in which the oxygen atom forms part of a 3-membered ring. http://purl.obolibrary.org/obo/CHEBI_33229 vitamin (role) http://purl.obolibrary.org/obo/CHEBI_27027 micronutrient A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines. http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_24432 biological role A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. http://purl.obolibrary.org/obo/CHEBI_33282 antibacterial agent http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent A substance (or active part thereof) that kills or slows the growth of bacteria. http://purl.obolibrary.org/obo/CHEBI_33308 carboxylic ester http://purl.obolibrary.org/obo/CHEBI_35701 ester An ester of a carboxylic acid, R1C(=O)OR2, where R1 = H or organyl and R2 = organyl. http://purl.obolibrary.org/obo/CHEBI_33551 organosulfonic acid http://purl.obolibrary.org/obo/CHEBI_64709 organic acid An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon. http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion An amino-acid anion obtained by deprotonation of any α-amino acid. http://purl.obolibrary.org/obo/CHEBI_33572 resorcinols http://purl.obolibrary.org/obo/CHEBI_33570 benzenediols Any benzenediol in which the two hydroxy groups are meta to one another. http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid A carbon oxoacid acid carrying at least one ‒C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. http://purl.obolibrary.org/obo/CHEBI_33599 spiro compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound A compound having one atom as the only common member of two rings. http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid An amino acid in which the amino group is located on the carbon atom at the position α to the carboxy group. http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound A heterocyclic compound formally derived from an arene by replacement of one or more methine (‒C=) and/or vinylene (‒CH=CH‒) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous π-electron system characteristic of aromatic systems and a number of out-of-plane π-electrons corresponding to the Hückel rule (4n+2). http://purl.obolibrary.org/obo/CHEBI_33853 phenols http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. http://purl.obolibrary.org/obo/CHEBI_33859 aromatic carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring. http://purl.obolibrary.org/obo/CHEBI_33860 aromatic amine http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound An amino compound in which the amino group is linked directly to an aromatic system. http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene http://purl.obolibrary.org/obo/CHEBI_35186 terpene A C15 terpene. http://purl.obolibrary.org/obo/CHEBI_35221 antimetabolite http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative http://purl.obolibrary.org/obo/CHEBI_33702 polyatomic cation A derivative of ammonium, NH4+, in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc). http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity Any heteroorganic entity containing at least one carbon-nitrogen bond. http://purl.obolibrary.org/obo/CHEBI_35358 sulfonamide http://purl.obolibrary.org/obo/CHEBI_33256 primary amide An amide of a sulfonic acid RS(=O)2NR'2. http://purl.obolibrary.org/obo/CHEBI_35366 fatty acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids. http://purl.obolibrary.org/obo/CHEBI_35411 alkane-alpha,omega-diamine http://purl.obolibrary.org/obo/CHEBI_46687 diazaalkane A primary diamine that is ethane or a higher alkane in which a hydrogen of each of the terminal methyl groups has been replaced by an amino group. H2NCH2(CH2)nCH2NH2, where n = 0, 1, 2, etc. http://purl.obolibrary.org/obo/CHEBI_35441 antiinfective agent http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance used in the prophylaxis or therapy of infectious diseases. http://purl.obolibrary.org/obo/CHEBI_35470 central nervous system drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. http://purl.obolibrary.org/obo/CHEBI_35472 anti-inflammatory drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance that reduces or suppresses inflammation. http://purl.obolibrary.org/obo/CHEBI_35475 non-steroidal anti-inflammatory drug http://purl.obolibrary.org/obo/CHEBI_35842 antirheumatic drug An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. http://purl.obolibrary.org/obo/CHEBI_35488 central nervous system depressant http://purl.obolibrary.org/obo/CHEBI_35470 central nervous system drug A loosely defined group of drugs that tend to reduce the activity of the central nervous system. http://purl.obolibrary.org/obo/CHEBI_35489 organic disulfide http://purl.obolibrary.org/obo/CHEBI_48343 disulfide Compounds of structure RSSR in which R and R' are organic groups. http://purl.obolibrary.org/obo/CHEBI_35498 diuretic http://purl.obolibrary.org/obo/CHEBI_23888 drug An agent that promotes the excretion of urine through its effects on kidney function. http://purl.obolibrary.org/obo/CHEBI_35610 antineoplastic agent http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance that inhibits or prevents the proliferation of neoplasms. http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound Any ether in which the oxygen is attached to at least one aryl substituent. http://purl.obolibrary.org/obo/CHEBI_35620 vasodilator agent http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug A drug used to cause dilation of the blood vessels. http://purl.obolibrary.org/obo/CHEBI_35623 anticonvulsant http://purl.obolibrary.org/obo/CHEBI_35488 central nervous system depressant A drug used to prevent seizures or reduce their severity. http://purl.obolibrary.org/obo/CHEBI_35674 antihypertensive agent http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug Any drug used in the treatment of acute or chronic vascular hypertension regardless of pharmacological mechanism. http://purl.obolibrary.org/obo/CHEBI_35681 secondary alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A secondary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it. http://purl.obolibrary.org/obo/CHEBI_35703 xenobiotic http://purl.obolibrary.org/obo/CHEBI_24432 biological role A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. http://purl.obolibrary.org/obo/CHEBI_35718 antifungal agent http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. http://purl.obolibrary.org/obo/CHEBI_35727 triazoles http://purl.obolibrary.org/obo/CHEBI_68452 azole An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms. http://purl.obolibrary.org/obo/CHEBI_35871 oxo monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_25754 oxo carboxylic acid Any monocarboxylic acid having at least one additional oxo functional group. http://purl.obolibrary.org/obo/CHEBI_36047 antibacterial drug http://purl.obolibrary.org/obo/CHEBI_36043 antimicrobial drug A drug used to treat or prevent bacterial infections. http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. http://purl.obolibrary.org/obo/CHEBI_36683 organochlorine compound http://purl.obolibrary.org/obo/CHEBI_23117 chlorine molecular entity An organochlorine compound is a compound containing at least one carbon-chlorine bond. http://purl.obolibrary.org/obo/CHEBI_36709 aminoquinoline http://purl.obolibrary.org/obo/CHEBI_33860 aromatic amine Any member of the class of quinolines in which the quinoline skeleton is substituted by one or more amino or substituted-amino groups. http://purl.obolibrary.org/obo/CHEBI_36820 ring assembly http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved. http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound An organochalcogen compound containing at least one carbon-oxygen bond. http://purl.obolibrary.org/obo/CHEBI_37143 organofluorine compound http://purl.obolibrary.org/obo/CHEBI_17792 organohalogen compound An organofluorine compound is a compound containing at least one carbon-fluorine bond. http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide http://purl.obolibrary.org/obo/CHEBI_33256 primary amide An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the ‒C(=O)NH2 group including its carbon atom. http://purl.obolibrary.org/obo/CHEBI_37948 oxaspiro compound http://purl.obolibrary.org/obo/CHEBI_33599 spiro compound A spiro compound in which at least one of the cyclic components is an oxygen heterocyle. http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any organic heterocyclic compound containing at least one ring oxygen atom. http://purl.obolibrary.org/obo/CHEBI_38215 calcium channel blocker http://purl.obolibrary.org/obo/CHEBI_48706 antagonist One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. http://purl.obolibrary.org/obo/CHEBI_38582 difluorobenzene http://purl.obolibrary.org/obo/CHEBI_35496 fluorobenzenes Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying two fluorine atoms. http://purl.obolibrary.org/obo/CHEBI_38785 morpholines http://purl.obolibrary.org/obo/CHEBI_46952 oxazinane Any compound containing morpholine as part of its structure. http://purl.obolibrary.org/obo/CHEBI_38922 dibenzofurans http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any organic heterotricyclic compound based on a dibenzofuran skeleton and its substituted derivatives thereof. http://purl.obolibrary.org/obo/CHEBI_39410 1,2,4-triazines http://purl.obolibrary.org/obo/CHEBI_38102 triazines Any compound with a 1,2,4-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 2 and 4 of the core benzene ring structure. http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines http://purl.obolibrary.org/obo/CHEBI_38313 diazines Any compound having a pyrimidine as part of its structure. http://purl.obolibrary.org/obo/CHEBI_45373 sulfanilamide http://purl.obolibrary.org/obo/CHEBI_87228 sulfonamide antibiotic A sulfonamide in which the sulfamoyl functional group is attached to aniline at the 4-position. http://purl.obolibrary.org/obo/CHEBI_46761 dipeptide http://purl.obolibrary.org/obo/CHEBI_25676 oligopeptide Any molecule that contains two amino-acid residues connected by peptide linkages. http://purl.obolibrary.org/obo/CHEBI_46942 oxanes http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any organic heteromonocyclic compoundthat is oxane or its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_48422 angiogenesis inhibitor http://purl.obolibrary.org/obo/CHEBI_23888 drug An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. http://purl.obolibrary.org/obo/CHEBI_48901 thiazoles http://purl.obolibrary.org/obo/CHEBI_68452 azole An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom. http://purl.obolibrary.org/obo/CHEBI_49167 anti-asthmatic drug http://purl.obolibrary.org/obo/CHEBI_65023 anti-asthmatic agent A drug used to treat asthma. http://purl.obolibrary.org/obo/CHEBI_50176 keratolytic drug http://purl.obolibrary.org/obo/CHEBI_50177 dermatologic drug A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. http://purl.obolibrary.org/obo/CHEBI_50183 P450 inhibitor http://purl.obolibrary.org/obo/CHEBI_76898 EC 1.14.14.1 (unspecific monooxygenase) inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. http://purl.obolibrary.org/obo/CHEBI_50249 anticoagulant http://purl.obolibrary.org/obo/CHEBI_50248 hematologic agent An agent that prevents blood clotting. http://purl.obolibrary.org/obo/CHEBI_50267 protective agent http://purl.obolibrary.org/obo/CHEBI_23888 drug Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent. http://purl.obolibrary.org/obo/CHEBI_50750 EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor http://purl.obolibrary.org/obo/CHEBI_70727 topoisomerase inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_33582 carbon group molecular entity Any molecular entity that contains carbon. http://purl.obolibrary.org/obo/CHEBI_50903 carcinogenic agent http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. http://purl.obolibrary.org/obo/CHEBI_50995 secondary amino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups. http://purl.obolibrary.org/obo/CHEBI_51373 GABA agonist http://purl.obolibrary.org/obo/CHEBI_51374 GABA agent A drug that binds to and activates γ-aminobutyric acid receptors. http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzenes http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups. http://purl.obolibrary.org/obo/CHEBI_51689 enone http://purl.obolibrary.org/obo/CHEBI_51721 alpha,beta-unsaturated ketone An α,β-unsaturated ketone of general formula R1R2C=CR3‒C(=O)R4 (R4 ≠ H) in which the C=O function is conjugated to a C=C double bond at the α,β position. http://purl.obolibrary.org/obo/CHEBI_52214 ligand http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any molecule or ion capable of binding to a central metal atom to form coordination complexes. http://purl.obolibrary.org/obo/CHEBI_5280 gatifloxacin http://purl.obolibrary.org/obo/CHEBI_86324 quinolone antibiotic A monocarboxylic acid that is 4-oxo-1,4-dihydroquinoline-3-carboxylic acid which is substituted on the nitrogen by a cyclopropyl group and at positions 6, 7, and 8 by fluoro, 3-methylpiperazin-1-yl, and methoxy groups, respectively. Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial topoisomerase type-II enzymes. http://purl.obolibrary.org/obo/CHEBI_52898 azamacrocycle http://purl.obolibrary.org/obo/CHEBI_51026 macrocycle A cyclic macromolecule containing one or more nitrogen atoms in place of carbon either as the divalent group NH for the group CH2 or a single trivalent nitrogen atom for the group CH. http://purl.obolibrary.org/obo/CHEBI_53559 topoisomerase IV inhibitor http://purl.obolibrary.org/obo/CHEBI_70727 topoisomerase inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase IV, which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. http://purl.obolibrary.org/obo/CHEBI_55370 imidazolidinone http://purl.obolibrary.org/obo/CHEBI_38261 imidazolidines An imidazolidine containing one or more oxo groups. http://purl.obolibrary.org/obo/CHEBI_55373 isoxazoles http://purl.obolibrary.org/obo/CHEBI_35790 oxazole Oxazoles in which the N and O atoms are adjacent. http://purl.obolibrary.org/obo/CHEBI_55517 trichothecene http://purl.obolibrary.org/obo/CHEBI_32955 epoxide Any one of a large family of chemically related mycotoxins with a structure based on a sesquiterpene skeleton. The most important structural features causing the biological activities of trichothecenes are a 12,13-epoxy ring, the presence of hydroxy or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain. http://purl.obolibrary.org/obo/CHEBI_59107 EC 3.4.24.* (metalloendopeptidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_37670 protease inhibitor Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*). http://purl.obolibrary.org/obo/CHEBI_59517 DNA synthesis inhibitor http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor Any substance that inhibits the synthesis of DNA. http://purl.obolibrary.org/obo/CHEBI_60027 polymer http://purl.obolibrary.org/obo/CHEBI_60004 mixture A polymer is a mixture, which is composed of macromolecules of different kinds and which may be differentiated by composition, length, degree of branching etc.. http://purl.obolibrary.org/obo/CHEBI_60783 nucleoside analogue http://purl.obolibrary.org/obo/CHEBI_21731 N-glycosyl compound An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells. http://purl.obolibrary.org/obo/CHEBI_60911 racemate http://purl.obolibrary.org/obo/CHEBI_60004 mixture A racemate is an equimolar mixture of a pair of enantiomers. http://purl.obolibrary.org/obo/CHEBI_62070 nalidixic acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of nalidixic acid; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_62733 aromatic amide http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound An amide in which the amide linkage is bonded directly to an aromatic system. http://purl.obolibrary.org/obo/CHEBI_62868 hepatoprotective agent http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any compound that is able to prevent damage to the liver. http://purl.obolibrary.org/obo/CHEBI_63367 monosaccharide derivative http://purl.obolibrary.org/obo/CHEBI_63299 carbohydrate derivative A carbohydrate derivative that is formally obtained from a monosaccharide. http://purl.obolibrary.org/obo/CHEBI_63726 neuroprotective agent http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any compound that can be used for the treatment of neurodegenerative disorders. http://purl.obolibrary.org/obo/CHEBI_64459 biaryl http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond. http://purl.obolibrary.org/obo/CHEBI_65023 anti-asthmatic agent http://purl.obolibrary.org/obo/CHEBI_33232 application Any compound that has anti-asthmatic effects. http://purl.obolibrary.org/obo/CHEBI_68495 apoptosis inducer http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. http://purl.obolibrary.org/obo/CHEBI_73080 hemiaminal http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound Any organic amino compound that has an amino group and a hydroxy group attached to the same carbon atom. Hemiaminals are intermediates in the formation of imines by addition of an amine to an aldehyde or ketone; those derived from primary amines are particularly unstable. http://purl.obolibrary.org/obo/CHEBI_73474 acetylenic compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule Any organic molecule containing a C≡C bond. http://purl.obolibrary.org/obo/CHEBI_73537 1,8-naphthyridine derivative http://purl.obolibrary.org/obo/CHEBI_73539 naphthyridine derivative Any naphthyridine derivative that is a derivative of 1,8-naphthyridine. http://purl.obolibrary.org/obo/CHEBI_75767 animal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals. http://purl.obolibrary.org/obo/CHEBI_75771 mouse metabolite http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). http://purl.obolibrary.org/obo/CHEBI_76924 plant metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. http://purl.obolibrary.org/obo/CHEBI_76946 fungal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. http://purl.obolibrary.org/obo/CHEBI_76971 Escherichia coli metabolite http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. http://purl.obolibrary.org/obo/CHEBI_7731 ofloxacin http://purl.obolibrary.org/obo/CHEBI_87211 fluoroquinolone antibiotic A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. http://purl.obolibrary.org/obo/CHEBI_78298 environmental contaminant http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any minor or unwanted substance introduced into the environment that can have undesired effects. http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity that contains at least one C=C bond. http://purl.obolibrary.org/obo/CHEBI_83575 monofluorobenzenes http://purl.obolibrary.org/obo/CHEBI_35496 fluorobenzenes Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent. http://purl.obolibrary.org/obo/CHEBI_83925 non-proteinogenic alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid Any α-amino acid which is not a member of the group of 23 proteinogenic amino acids. http://purl.obolibrary.org/obo/CHEBI_86324 quinolone antibiotic http://purl.obolibrary.org/obo/CHEBI_25558 organonitrogen heterocyclic antibiotic An organonitrogen heterocyclic antibiotic whose structure contains a quinolone or quinolone-related skeleton. http://purl.obolibrary.org/obo/CHEBI_87071 conazole antifungal drug http://purl.obolibrary.org/obo/CHEBI_86323 conazole antifungal agent Any conazole antifungal agent that has been used for the treatment of fungal infections in animals or humans. http://purl.obolibrary.org/obo/CHEBI_87101 triazole antifungal drug http://purl.obolibrary.org/obo/CHEBI_86426 triazole antifungal agent Any triazole antifungal agent that has been used for the treatment of fungal infections in humans or animals. http://purl.obolibrary.org/obo/CHEBI_87211 fluoroquinolone antibiotic http://purl.obolibrary.org/obo/CHEBI_37143 organofluorine compound An organonitrogen heterocyclic antibiotic containing a quinolone (or quinolone-like) moiety and which have a fluorine atom attached to the central ring system. http://purl.obolibrary.org/obo/CHEBI_87228 sulfonamide antibiotic http://purl.obolibrary.org/obo/CHEBI_35358 sulfonamide A class of sulfonamides whose members generally have bacteriostatic antibiotic properties. http://purl.obolibrary.org/obo/CHEBI_88188 drug allergen http://purl.obolibrary.org/obo/CHEBI_23888 drug Any drug which causes the onset of an allergic reaction. http://purl.obolibrary.org/obo/CHEBI_16150 benzoate http://purl.obolibrary.org/obo/CHEBI_22718 benzoates The simplest member of the class of benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1. http://purl.obolibrary.org/obo/CHEBI_17418 valeric acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A straight-chain saturated fatty acid containing five carbon atoms. http://purl.obolibrary.org/obo/CHEBI_18320 1,4-dithiothreitol http://purl.obolibrary.org/obo/CHEBI_25189 1,4-dimercaptobutane-2,3-diol The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol. http://purl.obolibrary.org/obo/CHEBI_204928 cefotaxime http://purl.obolibrary.org/obo/CHEBI_38418 1,3-thiazoles A cephalosporin compound having acetoxymethyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups. http://purl.obolibrary.org/obo/CHEBI_26401 purines http://purl.obolibrary.org/obo/CHEBI_35875 imidazopyrimidine A class of imidazopyrimidines that consists of purine and its substituted derivatives. http://purl.obolibrary.org/obo/CHEBI_27136 triol http://purl.obolibrary.org/obo/CHEBI_26191 polyol A chemical compound containing three hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_27314 water-soluble vitamin (role) http://purl.obolibrary.org/obo/CHEBI_33229 vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. http://purl.obolibrary.org/obo/CHEBI_28077 rifampicin http://purl.obolibrary.org/obo/CHEBI_46847 N-iminopiperazine A member of the class of rifamycins that is a a semisynthetic antibiotic derived from Amycolatopsis rifamycinica (previously known as Amycolatopsis mediterranei and Streptomyces mediterranei). http://purl.obolibrary.org/obo/CHEBI_33555 arenesulfonic acid http://purl.obolibrary.org/obo/CHEBI_33551 organosulfonic acid Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an aryl group. http://purl.obolibrary.org/obo/CHEBI_33655 aromatic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekulé structure) is said to possess aromatic character. http://purl.obolibrary.org/obo/CHEBI_35692 dicarboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid containing two carboxy groups. http://purl.obolibrary.org/obo/CHEBI_42355 erythromycin A http://purl.obolibrary.org/obo/CHEBI_48923 erythromycin An erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. http://purl.obolibrary.org/obo/CHEBI_50185 fatty acid synthesis inhibitor http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor Any pathway inhibitor that inhibits the synthesis of fatty acids. http://purl.obolibrary.org/obo/CHEBI_50994 primary amino compound http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group. http://purl.obolibrary.org/obo/CHEBI_59777 ketal http://purl.obolibrary.org/obo/CHEBI_59769 acetal An acetal of formula R2C(OR)2 (R ≠ H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals. http://purl.obolibrary.org/obo/CHEBI_59835 hydroxy fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion The conjugate base of any hydroxy fatty acid, formed by deprotonation of the carboxylic acid moiety. http://purl.obolibrary.org/obo/CHEBI_63247 reducing agent http://purl.obolibrary.org/obo/CHEBI_51086 chemical role The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species. http://purl.obolibrary.org/obo/CHEBI_64577 flour treatment agent http://purl.obolibrary.org/obo/CHEBI_64047 food additive A food additive which is added to flour or dough to improve baking quality and/or colour. http://purl.obolibrary.org/obo/CHEBI_64996 EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_35856 lipoxygenase inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). http://purl.obolibrary.org/obo/CHEBI_65001 EC 3.1.1.3 (triacylglycerol lipase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76773 EC 3.1.1.* (carboxylic ester hydrolase) inhibitor Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3). http://purl.obolibrary.org/obo/CHEBI_65256 antimicrobial food preservative http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms. http://purl.obolibrary.org/obo/CHEBI_76969 bacterial metabolite http://purl.obolibrary.org/obo/CHEBI_75787 prokaryotic metabolite Any prokaryotic metabolite produced during a metabolic reaction in bacteria. http://purl.obolibrary.org/obo/CHEBI_79020 alpha,beta-unsaturated monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C≡C bond. http://purl.obolibrary.org/obo/CHEBI_84735 algal metabolite http://purl.obolibrary.org/obo/CHEBI_75763 eukaryotic metabolite Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae. http://purl.obolibrary.org/obo/CHEBI_25435 mutagen http://purl.obolibrary.org/obo/CHEBI_50902 genotoxin An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution. http://purl.obolibrary.org/obo/CHEBI_26895 tetracyclines http://purl.obolibrary.org/obo/CHEBI_26188 polyketide A subclass of polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups. http://purl.obolibrary.org/obo/CHEBI_33497 transition element molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity containing one or more atoms of a transition element. http://purl.obolibrary.org/obo/CHEBI_35442 antiparasitic agent http://purl.obolibrary.org/obo/CHEBI_35441 antiinfective agent A substance used to treat or prevent parasitic infections. http://purl.obolibrary.org/obo/CHEBI_53000 epitope http://purl.obolibrary.org/obo/CHEBI_24432 biological role The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. http://purl.obolibrary.org/obo/CHEBI_55374 oxazolidinone http://purl.obolibrary.org/obo/CHEBI_38329 oxazolidines An oxazolidine containing one or more oxo groups. http://purl.obolibrary.org/obo/CHEBI_72588 semisynthetic derivative http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity derived from a natural product by partial chemical synthesis. http://purl.obolibrary.org/obo/CHEBI_17522 alditol http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group). http://purl.obolibrary.org/obo/CHEBI_18133 hexose http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose). http://purl.obolibrary.org/obo/CHEBI_24650 hydroxamic acid http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A compound, RkE(=O)lNHOH, derived from an oxoacid RkE(=O)l(OH) (l ≠ 0) by replacing ‒OH with ‒NHOH, and derivatives thereof. Specific examples of hydroxamic acids are preferably named as N-hydroxy amides. http://purl.obolibrary.org/obo/CHEBI_30751 formic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects. http://purl.obolibrary.org/obo/CHEBI_35213 cyclodepsipeptide http://purl.obolibrary.org/obo/CHEBI_23643 depsipeptide A depsipeptide in which the amino and hydroxy carboxylic acid residues are connected in a ring. http://purl.obolibrary.org/obo/CHEBI_35381 monosaccharide http://purl.obolibrary.org/obo/CHEBI_16646 carbohydrate Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H‒[CHOH]n‒C(=O)[CHOH]m‒H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group. http://purl.obolibrary.org/obo/CHEBI_38070 anti-arrhythmia drug http://purl.obolibrary.org/obo/CHEBI_35554 cardiovascular drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. http://purl.obolibrary.org/obo/CHEBI_61115 EC 3.5.1.98 (histone deacetylase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98). http://purl.obolibrary.org/obo/CHEBI_161680 aztreonam http://purl.obolibrary.org/obo/CHEBI_88225 beta-lactam antibiotic allergen A synthetic monocyclic β-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking. http://purl.obolibrary.org/obo/CHEBI_164200 triclosan http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes An aromatic ether that is phenol which is substituted at C-5 by a chloro group and at C-2 by a 2,4-dichlorophenoxy group. It is widely used as a preservative and antimicrobial agent in personal care products such as soaps, skin creams, toothpaste and deodorants as well as in household items such as plastic chopping boards, sports equipment and shoes. http://purl.obolibrary.org/obo/CHEBI_16541 protein polypeptide chain http://purl.obolibrary.org/obo/CHEBI_15841 polypeptide A naturally occurring polypeptide synthesized at the ribosome. http://purl.obolibrary.org/obo/CHEBI_16705 6-aminopenicillanic acid http://purl.obolibrary.org/obo/CHEBI_25865 penicillanic acids A penicillanic acid compound having a (6R)-amino substituent. The active nucleus common to all penicillins, it may be substituted at the 6-amino position to form the semisynthetic penicillins, resulting in a variety of antibacterial and pharmacologic characteristics. http://purl.obolibrary.org/obo/CHEBI_24318 glutamine family amino acid http://purl.obolibrary.org/obo/CHEBI_83813 proteinogenic amino acid An L-α-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class. http://purl.obolibrary.org/obo/CHEBI_24396 glycopeptide http://purl.obolibrary.org/obo/CHEBI_16670 peptide Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide. http://purl.obolibrary.org/obo/CHEBI_24669 hydroxy carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any carboxylic acid with at least one hydroxy group. http://purl.obolibrary.org/obo/CHEBI_24837 inorganic peroxide http://purl.obolibrary.org/obo/CHEBI_24836 inorganic oxide Compounds of structure ROOR' in which R and R' are inorganic groups. http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity. http://purl.obolibrary.org/obo/CHEBI_25388 monohydroxybenzoate http://purl.obolibrary.org/obo/CHEBI_24675 hydroxybenzoate A hydroxybenzoate carrying a single hydroxy substituent at unspecified position. http://purl.obolibrary.org/obo/CHEBI_25608 nucleoside phosphate http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates. http://purl.obolibrary.org/obo/CHEBI_25750 oxime http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes. http://purl.obolibrary.org/obo/CHEBI_26078 phosphoric acid http://purl.obolibrary.org/obo/CHEBI_59698 phosphoric acids A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. http://purl.obolibrary.org/obo/CHEBI_26115 phytoalexin http://purl.obolibrary.org/obo/CHEBI_38231 phytotoxin A toxin made by a plant that acts against an organism attacking it. http://purl.obolibrary.org/obo/CHEBI_26130 biological pigment http://purl.obolibrary.org/obo/CHEBI_52208 biophysical role An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light. http://purl.obolibrary.org/obo/CHEBI_26199 polyprenol http://purl.obolibrary.org/obo/CHEBI_26244 prenols Any member of the class of prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units. http://purl.obolibrary.org/obo/CHEBI_26244 prenols http://purl.obolibrary.org/obo/CHEBI_30879 alcohol Any alcohol possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of one or more isoprene units (biogenetic precursors of the isoprenoids). http://purl.obolibrary.org/obo/CHEBI_26271 proline http://purl.obolibrary.org/obo/CHEBI_33704 alpha-amino acid An α-amino acid that is pyrrolidine bearing a carboxy substituent at position 2. http://purl.obolibrary.org/obo/CHEBI_26523 reactive oxygen species http://purl.obolibrary.org/obo/CHEBI_25806 oxygen molecular entity Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. http://purl.obolibrary.org/obo/CHEBI_26822 sulfide http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity Any sulfur molecular entity that involves either covalently bonded or anionic sulfur. http://purl.obolibrary.org/obo/CHEBI_26888 tetrachlorobenzene http://purl.obolibrary.org/obo/CHEBI_23132 chlorobenzenes Any member of the class of chlorobenzenes carrying four chloro groups at unspecified positions. http://purl.obolibrary.org/obo/CHEBI_27405 streptidine http://purl.obolibrary.org/obo/CHEBI_24436 guanidines An amino cyclitol that is scyllo-inositol in which the hydroxy groups at positions 1 and 3 are replaced by guanidino groups. http://purl.obolibrary.org/obo/CHEBI_28600 farnesol http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol A farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1. http://purl.obolibrary.org/obo/CHEBI_28938 ammonium http://purl.obolibrary.org/obo/CHEBI_50313 onium cation An onium cation obtained by protonation of ammonia. http://purl.obolibrary.org/obo/CHEBI_29700 tylactone http://purl.obolibrary.org/obo/CHEBI_51689 enone A 16-membererd macrolide that is the aglycone of the antibiotic 5-O-β-D-mycaminosyltylactone. http://purl.obolibrary.org/obo/CHEBI_32867 D-prolinate http://purl.obolibrary.org/obo/CHEBI_32871 prolinate An optically active form of prolinate having D-configuration. http://purl.obolibrary.org/obo/CHEBI_32868 D-prolinium http://purl.obolibrary.org/obo/CHEBI_32872 prolinium An optically active form of prolinium having D-configuration. http://purl.obolibrary.org/obo/CHEBI_33256 primary amide http://purl.obolibrary.org/obo/CHEBI_32988 amide A derivative of an oxoacid RkE(=O)l(OH)m (l ≠ 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/CHEBI_33287 fertilizer http://purl.obolibrary.org/obo/CHEBI_33286 agrochemical A fertilizer is any substance that is added to soil or water to assist the growth of plants. http://purl.obolibrary.org/obo/CHEBI_33405 hydracid http://purl.obolibrary.org/obo/CHEBI_33608 hydrogen molecular entity A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/CHEBI_33457 phosphorus oxoacid http://purl.obolibrary.org/obo/CHEBI_33408 pnictogen oxoacid A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons. http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule http://purl.obolibrary.org/obo/CHEBI_36357 polyatomic entity A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/CHEBI_35275 S-glycosyl compound http://purl.obolibrary.org/obo/CHEBI_59793 monothioacetal A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and a S atom bound to a carbon atom, thus creating a C-S bond. http://purl.obolibrary.org/obo/CHEBI_35515 5alpha-cholestane http://purl.obolibrary.org/obo/CHEBI_35516 cholestane The 5α-stereoisomer of cholestane. http://purl.obolibrary.org/obo/CHEBI_35679 antilipemic drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter. http://purl.obolibrary.org/obo/CHEBI_36043 antimicrobial drug http://purl.obolibrary.org/obo/CHEBI_35441 antiinfective agent A drug used to treat or prevent microbial infections. http://purl.obolibrary.org/obo/CHEBI_37848 plant hormone http://purl.obolibrary.org/obo/CHEBI_24621 hormone A plant growth regulator that modulates the formation of stems, leaves and flowers, as well as the development and ripening of fruit. The term includes endogenous and non-endogenous compounds (e.g. active compounds produced by bacteria on the leaf surface) as well as semi-synthetic and fully synthetic compounds. http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid http://purl.obolibrary.org/obo/CHEBI_59202 straight-chain fatty acid Any saturated fatty acid lacking a side-chain. http://purl.obolibrary.org/obo/CHEBI_39474 polyazaalkane http://purl.obolibrary.org/obo/CHEBI_46686 azaalkane Any azaalkane in which two or more carbons in the chain are replaced by nitrogen. http://purl.obolibrary.org/obo/CHEBI_4167 D-glucopyranose http://purl.obolibrary.org/obo/CHEBI_17634 D-glucose A glucopyranose having D-configuration. http://purl.obolibrary.org/obo/CHEBI_46787 solvent http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A liquid that can dissolve other substances (solutes) without any change in their chemical composition. http://purl.obolibrary.org/obo/CHEBI_48219 disinfectant http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity. http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent http://purl.obolibrary.org/obo/CHEBI_46787 solvent A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds. http://purl.obolibrary.org/obo/CHEBI_50248 hematologic agent http://purl.obolibrary.org/obo/CHEBI_23888 drug Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. http://purl.obolibrary.org/obo/CHEBI_50276 EC 5.99.1.2 (DNA topoisomerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_70727 topoisomerase inhibitor A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. http://purl.obolibrary.org/obo/CHEBI_50584 alkyl alcohol http://purl.obolibrary.org/obo/CHEBI_2571 aliphatic alcohol An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position. http://purl.obolibrary.org/obo/CHEBI_50696 EC 2.4.1.129 (peptidoglycan glycosyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76789 EC 2.4.1.* (hexosyltransferase) inhibitor An EC 2.4.1.* (hexosyltransferase) inhibitor that interferes with the action of peptidoglycan glycosyltransferase (EC 2.4.1.129). http://purl.obolibrary.org/obo/CHEBI_50847 immunological adjuvant http://purl.obolibrary.org/obo/CHEBI_50846 immunomodulator A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. http://purl.obolibrary.org/obo/CHEBI_52362 ortho-fused heteroarene http://purl.obolibrary.org/obo/CHEBI_33637 ortho-fused compound An ortho-fused compound in which at least one of the rings contains at least one heteroatom. http://purl.obolibrary.org/obo/CHEBI_57726 D-proline zwitterion http://purl.obolibrary.org/obo/CHEBI_59871 D-alpha-amino acid zwitterion A D-α-amino acid zwitterion that is D-proline in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57869 6-aminopenicillanic acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion Zwitterionic form of 6-aminopenicillanic acid arising from migration of a proton from the carboxy group to the 6-amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_57971 hygromycin B(3+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An ammonium ion that is the trication of hygromycin B arising from protonation of the three amino groups; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58007 streptomycin(3+) http://purl.obolibrary.org/obo/CHEBI_60251 guanidinium ion Trication of streptomycin arising from protonation of the guanidino and secondary amino groups. http://purl.obolibrary.org/obo/CHEBI_58954 straight-chain saturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion lacking a carbon side-chain. http://purl.obolibrary.org/obo/CHEBI_59647 EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76878 EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50). http://purl.obolibrary.org/obo/CHEBI_59871 D-alpha-amino acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion Zwitterionic form of a D-α-amino acid having an anionic carboxy group and a protonated amino group. http://purl.obolibrary.org/obo/CHEBI_60240 divalent metal cation http://purl.obolibrary.org/obo/CHEBI_64641 divalent inorganic cation A metal cation with a valence of two. http://purl.obolibrary.org/obo/CHEBI_60832 tubulin modulator http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules. http://purl.obolibrary.org/obo/CHEBI_60895 D-alpha-amino acid anion http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion Any α-amino acid anion in which the parent amino acid has D-configuration. http://purl.obolibrary.org/obo/CHEBI_61951 microtubule-destabilising agent http://purl.obolibrary.org/obo/CHEBI_60832 tubulin modulator Any substance that interacts with tubulin to inhibit polymerisation of microtubules. http://purl.obolibrary.org/obo/CHEBI_62913 EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76790 EC 2.4.2.* (pentosyltransferase) inhibitor An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD+ ADP-ribosyltransferase (EC 2.4.2.30). http://purl.obolibrary.org/obo/CHEBI_63490 explosive http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A substance capable of undergoing rapid and highly exothermic decomposition. http://purl.obolibrary.org/obo/CHEBI_71181 Sir2 inhibitor http://purl.obolibrary.org/obo/CHEBI_61115 EC 3.5.1.98 (histone deacetylase) inhibitor An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2. http://purl.obolibrary.org/obo/CHEBI_73181 EC 1.11.1.11 (L-ascorbate peroxidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_75381 EC 1.11.1.* (peroxidases) inhibitor An EC 1.11.1.* (peroxidases) inhibitor that inhibits the action of L-ascorbate peroxidase (EC 1.11.1.11). http://purl.obolibrary.org/obo/CHEBI_77194 EC 2.7.1.33 (pantothenate kinase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76881 EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of pantothenate kinase (EC 2.7.1.33). http://purl.obolibrary.org/obo/CHEBI_78295 food component http://purl.obolibrary.org/obo/CHEBI_52211 physiological role A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants. http://purl.obolibrary.org/obo/CHEBI_78433 refrigerant http://purl.obolibrary.org/obo/CHEBI_33232 application A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure. http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. http://purl.obolibrary.org/obo/CHEBI_79387 trivalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of three. http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion Any inorganic anion with a valency of one. http://purl.obolibrary.org/obo/CHEBI_83813 proteinogenic amino acid http://purl.obolibrary.org/obo/CHEBI_33709 amino acid Any of the 23 α-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration. http://purl.obolibrary.org/obo/CHEBI_84264 EC 3.5.1.19 (nicotinamidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19). http://purl.obolibrary.org/obo/CHEBI_87034 aromatic fungicide http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound An organic aromatic compound that has been used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_87064 benzimidazolylcarbamate fungicide http://purl.obolibrary.org/obo/CHEBI_87061 carbamate fungicide Any carbamate fungicide that contains a benzimidazolyl group attached to the nitrogen of the carbamate moiety. http://purl.obolibrary.org/obo/CHEBI_87114 antibiotic fungicide http://purl.obolibrary.org/obo/CHEBI_86478 antibiotic antifungal agent Any antibiotic antifungal agent that has been used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_22695 base http://purl.obolibrary.org/obo/CHEBI_51086 chemical role A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Brønsted base) or with the vacant orbital of some other molecular entity (Lewis base). http://purl.obolibrary.org/obo/CHEBI_23117 chlorine molecular entity http://purl.obolibrary.org/obo/CHEBI_24471 halogen molecular entity A halogen molecular entity containing one or more atoms of chlorine. http://purl.obolibrary.org/obo/CHEBI_23424 cyanides http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Salts and C-organyl derivatives of hydrogen cyanide, HC≡N. http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent A compound consisting of carbon and hydrogen only. http://purl.obolibrary.org/obo/CHEBI_25189 1,4-dimercaptobutane-2,3-diol http://purl.obolibrary.org/obo/CHEBI_22944 butanediols A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group. http://purl.obolibrary.org/obo/CHEBI_26739 sphingolipid http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone. http://purl.obolibrary.org/obo/CHEBI_27565 4-aminosalicylic acid http://purl.obolibrary.org/obo/CHEBI_22495 aminobenzoic acid An aminobenzoic acid that is salicylic acid substituted by an amino group at position 4. http://purl.obolibrary.org/obo/CHEBI_32845 serinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion An α-amino-acid anion that is the conjugate base of serine. http://purl.obolibrary.org/obo/CHEBI_32846 serinium http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation An α-amino-acid cation that is the conjugate acid of serine. http://purl.obolibrary.org/obo/CHEBI_32862 L-prolinate http://purl.obolibrary.org/obo/CHEBI_59814 L-alpha-amino acid anion An optically active form of prolinate having L-configuration. http://purl.obolibrary.org/obo/CHEBI_32864 L-prolinium http://purl.obolibrary.org/obo/CHEBI_32872 prolinium An optically active form of prolinium having L-configuration. http://purl.obolibrary.org/obo/CHEBI_33292 fuel http://purl.obolibrary.org/obo/CHEBI_33232 application An energy-rich substance that can be transformed with release of usable energy. http://purl.obolibrary.org/obo/CHEBI_33653 aliphatic compound http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds. http://purl.obolibrary.org/obo/CHEBI_33694 biomacromolecule http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A macromolecule formed by a living organism. http://purl.obolibrary.org/obo/CHEBI_33697 ribonucleic acid http://purl.obolibrary.org/obo/CHEBI_33696 nucleic acid High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins. http://purl.obolibrary.org/obo/CHEBI_33917 aldohexose http://purl.obolibrary.org/obo/CHEBI_18133 hexose A hexose with a (potential) aldehyde group at one end. http://purl.obolibrary.org/obo/CHEBI_35243 serine zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of serine. http://purl.obolibrary.org/obo/CHEBI_35359 carboxamidine http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the ‒C(=NH)NH2 group including its carbon atom. http://purl.obolibrary.org/obo/CHEBI_35436 D-glucoside http://purl.obolibrary.org/obo/CHEBI_24278 glucoside Any glucoside in which the glycoside group is derived from D-glucose. http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOyn− for some integers x, y and n. http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion http://purl.obolibrary.org/obo/CHEBI_33461 phosphorus oxoanion A phosphorus oxoanion that is the conjugate base of phosphoric acid. http://purl.obolibrary.org/obo/CHEBI_36027 stilbenol http://purl.obolibrary.org/obo/CHEBI_33853 phenols Any stilbenoid with at least one phenolic group. http://purl.obolibrary.org/obo/CHEBI_37578 halide http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements. http://purl.obolibrary.org/obo/CHEBI_37630 alpha-L-glucose http://purl.obolibrary.org/obo/CHEBI_37627 L-glucopyranose A L-glucopyranose with an α-configuration at the anomeric position. http://purl.obolibrary.org/obo/CHEBI_38500 EC 1.9.3.1 (cytochrome c oxidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_25355 mitochondrial respiratory-chain inhibitor An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1). http://purl.obolibrary.org/obo/CHEBI_38808 calcium channel modulator http://purl.obolibrary.org/obo/CHEBI_38632 membrane transport modulator A membrane transport modulator that is able to regulate intracellular calcium levels. http://purl.obolibrary.org/obo/CHEBI_4194 D-hexose http://purl.obolibrary.org/obo/CHEBI_18133 hexose A hexose that has D-configuration at position 5. http://purl.obolibrary.org/obo/CHEBI_43474 hydrogenphosphate http://purl.obolibrary.org/obo/CHEBI_35780 phosphate ion A phosphate ion that is the conjugate base of dihydrogenphosphate. http://purl.obolibrary.org/obo/CHEBI_46895 lipopeptide http://purl.obolibrary.org/obo/CHEBI_16670 peptide A compound consisting of a peptide with attached lipid. http://purl.obolibrary.org/obo/CHEBI_47867 indicator http://purl.obolibrary.org/obo/CHEBI_33232 application Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc. http://purl.obolibrary.org/obo/CHEBI_50471 primary arylamine http://purl.obolibrary.org/obo/CHEBI_33860 aromatic amine A primary amine formally derived from ammonia by replacing one hydrogen atom by an aryl group. R-NH2 where R is an aryl group. http://purl.obolibrary.org/obo/CHEBI_50846 immunomodulator http://purl.obolibrary.org/obo/CHEBI_23888 drug Biologically active substance whose activity affects or plays a role in the functioning of the immune system. http://purl.obolibrary.org/obo/CHEBI_50908 hepatotoxic agent http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A role played by a chemical compound exhibiting itself through the ability to induce damage to the liver in animals. http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_47811 penamcarboxylate Any anion formed by loss of a proton from the carboxy group of a penicillin. http://purl.obolibrary.org/obo/CHEBI_52090 methoxide http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the conjugate base of methanol. http://purl.obolibrary.org/obo/CHEBI_58165 3',5'-cyclic AMP(1-) http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58214 kanamycin A(4+) http://purl.obolibrary.org/obo/CHEBI_25697 organic cation A quadruply-charged organic cation arising from protonation of the four amino groups of kanamycin A; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_58464 nucleoside 3',5'-cyclic phosphate anion http://purl.obolibrary.org/obo/CHEBI_58945 organophosphate oxoanion The conjugate base of a nucleoside 3',5'-cyclic phosphate. http://purl.obolibrary.org/obo/CHEBI_59772 hemiketal http://purl.obolibrary.org/obo/CHEBI_5653 hemiacetal A hemiacetal having the structure RR1C(OH)OR2 (R, R1, R2 ≠ H), derived from a ketone by formal addition of an alcohol to the carbonyl group. http://purl.obolibrary.org/obo/CHEBI_60039 L-proline zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion The zwitterion formed from L-proline by proton transfer from the carboxy group to the ring nitrogen. It is the predominant species at physiological pH. http://purl.obolibrary.org/obo/CHEBI_6032 isonicotinic acid http://purl.obolibrary.org/obo/CHEBI_26420 pyridinemonocarboxylic acid A pyridinemonocarboxylic acid in which the carboxy group is at position 4 of the pyridine ring. http://purl.obolibrary.org/obo/CHEBI_61296 adenyl ribonucleotide http://purl.obolibrary.org/obo/CHEBI_61293 adenyl nucleotide A purine riboncleotide where adenine is the purine. http://purl.obolibrary.org/obo/CHEBI_77047 tylosin(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation that is the conjugate acid of tylosin, obtained by protonation of the tertiary amino group; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_83821 amino-acid derivative http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues. http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen http://purl.obolibrary.org/obo/CHEBI_17334 penicillin Any penicillin which causes the onset of an allergic reaction. http://purl.obolibrary.org/obo/CHEBI_30804 isophthalate(1-) http://purl.obolibrary.org/obo/CHEBI_35695 dicarboxylic acid monoanion A dicarboxylic acid monoanion that is the conjugate base of isophthalic acid. http://purl.obolibrary.org/obo/CHEBI_31286 bifonazole http://purl.obolibrary.org/obo/CHEBI_87069 imidazole antifungal drug A racemate comprising equimolar amounts of R- and S-bifonazole. It is a broad spectrum antifungal drug used for the treatment of fungal skin and nail infections. http://purl.obolibrary.org/obo/CHEBI_32161 sulfadimethoxine http://purl.obolibrary.org/obo/CHEBI_87228 sulfonamide antibiotic A sulfonamide consisting of pyrimidine having methoxy substituents at the 2- and 6-positions and a 4-aminobenzenesulfonamido group at the 4-position. http://purl.obolibrary.org/obo/CHEBI_46081 fluconazole http://purl.obolibrary.org/obo/CHEBI_87101 triazole antifungal drug A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis. http://purl.obolibrary.org/obo/CHEBI_473992 nystatin A1 http://purl.obolibrary.org/obo/CHEBI_59676 nystatins A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species. http://purl.obolibrary.org/obo/CHEBI_48132 tetracenomycin http://purl.obolibrary.org/obo/CHEBI_26188 polyketide A polyketide based on a tetracene ring structure. http://purl.obolibrary.org/obo/CHEBI_50103 excitatory amino acid agonist http://purl.obolibrary.org/obo/CHEBI_35942 neurotransmitter agent An agent that binds to and activates excitatory amino acid receptors. http://purl.obolibrary.org/obo/CHEBI_53662 biguanides http://purl.obolibrary.org/obo/CHEBI_24436 guanidines A class of oral hypoglycemic drugs used for diabetes mellitus or prediabetes treatment. They have a structure based on the 2-carbamimidoylguanidine skeleton. http://purl.obolibrary.org/obo/CHEBI_59285 EC 1.14.13.132 (squalene monooxygenase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76841 EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132). http://purl.obolibrary.org/obo/CHEBI_59349 cefepime(1+) http://purl.obolibrary.org/obo/CHEBI_23066 cephalosporin The conjugate acid of cefepime. http://purl.obolibrary.org/obo/CHEBI_59793 monothioacetal http://purl.obolibrary.org/obo/CHEBI_59792 thioacetal A thioacetal having the structure R2C(OR')(SR'). The term includes monothioketals, R ≠ H, as a subclass. http://purl.obolibrary.org/obo/CHEBI_71285 organophosphonate(2-) http://purl.obolibrary.org/obo/CHEBI_59635 organophosphonate oxoanion An organophosphonate oxoanion obtained by deprotonation of both phosphonate OH groups of any phosphonic acid. http://purl.obolibrary.org/obo/CHEBI_77884 EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor http://purl.obolibrary.org/obo/CHEBI_83734 sterol demethylation inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14α-demethylase). http://purl.obolibrary.org/obo/CHEBI_78128 fatty acid anion 24:0 http://purl.obolibrary.org/obo/CHEBI_58953 saturated fatty acid anion Any saturated fatty acid anion containing 24 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_78693 (R)-bifonazole http://purl.obolibrary.org/obo/CHEBI_78692 1-[biphenyl-4-yl(phenyl)methyl]imidazole A 1-[biphenyl-4-yl(phenyl)methyl]imidazole that is the R-enantiomer of bifonazole. http://purl.obolibrary.org/obo/CHEBI_78694 (S)-bifonazole http://purl.obolibrary.org/obo/CHEBI_78692 1-[biphenyl-4-yl(phenyl)methyl]imidazole A 1-[biphenyl-4-yl(phenyl)methyl]imidazole that is the S-enantiomer of bifonazole. http://purl.obolibrary.org/obo/CHEBI_87069 imidazole antifungal drug http://purl.obolibrary.org/obo/CHEBI_86420 imidazole antifungal agent Any imidazole antifungal agent that has been used for the treatment of fungal infections in humans or animals. http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide http://purl.obolibrary.org/obo/CHEBI_86426 triazole antifungal agent Any triazole antifungal agent that has been used as a fungicide. http://purl.obolibrary.org/obo/CHEBI_32588 potassium chloride http://purl.obolibrary.org/obo/CHEBI_190303 inorganic potassium salt A metal chloride salt with a K(+) counterion. http://purl.obolibrary.org/obo/CHEBI_33233 fundamental particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A particle not known to have substructure. http://purl.obolibrary.org/obo/CHEBI_33273 polyatomic anion http://purl.obolibrary.org/obo/CHEBI_36358 polyatomic ion An anion consisting of more than one atom. http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table. http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_25367 molecule Any molecule that consists of a series of atoms joined together to form a ring. http://purl.obolibrary.org/obo/CHEBI_33597 homocyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A cyclic compound having as ring members atoms of the same element only. http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound A molecule that features two fused rings. http://purl.obolibrary.org/obo/CHEBI_33637 ortho-fused compound http://purl.obolibrary.org/obo/CHEBI_35293 fused compound A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms. http://purl.obolibrary.org/obo/CHEBI_33641 olefin http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes. http://purl.obolibrary.org/obo/CHEBI_33662 annulene http://purl.obolibrary.org/obo/CHEBI_33664 monocyclic hydrocarbon A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms. http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound A polycyclic compound in which at least one of the rings contains at least one non-carbon atom. http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element. http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33497 transition element molecular entity A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element. http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity Hydrides are chemical compounds of hydrogen with other chemical elements. http://purl.obolibrary.org/obo/CHEBI_33710 alpha-amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33708 amino-acid residue An amino-acid residue derived from an α-amino acid. http://purl.obolibrary.org/obo/CHEBI_33847 monocyclic arene http://purl.obolibrary.org/obo/CHEBI_33658 arene A monocyclic aromatic hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_33848 polycyclic arene http://purl.obolibrary.org/obo/CHEBI_33666 polycyclic hydrocarbon A polycyclic aromatic hydrocarbon. http://purl.obolibrary.org/obo/CHEBI_3392 carbendazim http://purl.obolibrary.org/obo/CHEBI_87064 benzimidazolylcarbamate fungicide A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables. http://purl.obolibrary.org/obo/CHEBI_3393 carbenicillin http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen A penicillin antibiotic having a 6β-2-carboxy-2-phenylacetamido side-chain. http://purl.obolibrary.org/obo/CHEBI_3405 carboxin http://purl.obolibrary.org/obo/CHEBI_140325 secondary carboxamide An anilide obtained by formal condensation of the amino group of aniline with the carboxy group of 2-methyl-5,6-dihydro-1,4-oxathiine-3-carboxylic acid. A fungicide for control of bunts and smuts that is normally used as a seed treatment. http://purl.obolibrary.org/obo/CHEBI_35293 fused compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound A polycyclic compound that contains more than one ring with at least two common atoms (also known as bridgehead carbons) that are adjacent to each other. http://purl.obolibrary.org/obo/CHEBI_35297 acene http://purl.obolibrary.org/obo/CHEBI_51269 acenes A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement. http://purl.obolibrary.org/obo/CHEBI_36339 baryon http://purl.obolibrary.org/obo/CHEBI_36344 hadron Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek βαρυσ (heavy). http://purl.obolibrary.org/obo/CHEBI_36347 nuclear particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A nucleus or any of its constituents in any of their energy states. http://purl.obolibrary.org/obo/CHEBI_47956 thiocarboxamide http://purl.obolibrary.org/obo/CHEBI_33256 primary amide Any primary amide having its amide oxygen replaced by sulfur. http://purl.obolibrary.org/obo/CHEBI_51402 phenylenediamine http://purl.obolibrary.org/obo/CHEBI_33860 aromatic amine A benzene substituted with two amino groups. http://purl.obolibrary.org/obo/CHEBI_52211 physiological role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A biological role relating to the normal mechanisms and their interactions within a living system. http://purl.obolibrary.org/obo/CHEBI_60600 amide fungicide http://purl.obolibrary.org/obo/CHEBI_87012 amide antifungal agent Compounds that contain an amide group as a key feature of their structure and which have been used as fungicides. http://purl.obolibrary.org/obo/CHEBI_64709 organic acid http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity Any organic molecular entity that is acidic and contains carbon in covalent linkage. http://purl.obolibrary.org/obo/CHEBI_70977 alkane-alpha,omega-diammonium(2+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the amino groups of any alkane-α,ω-diamine; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_76042 aromatic amino-acid zwitterion http://purl.obolibrary.org/obo/CHEBI_35238 amino-acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid. http://purl.obolibrary.org/obo/CHEBI_83072 EC 1.3.5.1 [succinate dehydrogenase (quinone)] inhibitor http://purl.obolibrary.org/obo/CHEBI_77102 EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor An EC 1.3.5.* (oxidoreductase acting on CH-CH of donor with a quinone or related compound as acceptor) inhibitor that interferes with the action of succinate dehydrogenase (quinone), EC 1.3.5.1. http://purl.obolibrary.org/obo/CHEBI_91007 aromatic carboxylate http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_45081 pentamidine http://purl.obolibrary.org/obo/CHEBI_35359 carboxamidine A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease. http://purl.obolibrary.org/obo/CHEBI_4511 dicloxacillin http://purl.obolibrary.org/obo/CHEBI_23697 dichlorobenzene A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group. http://purl.obolibrary.org/obo/CHEBI_4520 diethofencarb http://purl.obolibrary.org/obo/CHEBI_87066 carbanilate fungicide A carbamate ester that is the isopropyl ester of (3,4-diethoxyphenyl)carbamic acid. A fungicide with strong activity against Botrytis cinerea and benzimidazole-resistant strains of Botryis spp. http://purl.obolibrary.org/obo/CHEBI_45285 pyrazinecarboxamide http://purl.obolibrary.org/obo/CHEBI_83628 N-acylammonia A monocarboxylic acid amide resulting from the formal condensation of the carboxy group of pyrazinoic acid (pyrazine-2-carboxylic acid) with ammonia. A prodrug for pyrazinoic acid, pyrazinecarboxamide is used as part of multidrug regimens for the treatment of tuberculosis. http://purl.obolibrary.org/obo/CHEBI_45615 salicylhydroxamic acid http://purl.obolibrary.org/obo/CHEBI_24650 hydroxamic acid A hydroxamic acid that is N-hydroxybenzamide carrying a phenolic hydroxy group at position 2. http://purl.obolibrary.org/obo/CHEBI_45979 thiabendazole http://purl.obolibrary.org/obo/CHEBI_38418 1,3-thiazoles A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium. http://purl.obolibrary.org/obo/CHEBI_46416 virginiamycin S1 http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic A cyclodepsipeptide that is N-(3-hydroxypicolinoyl)-L-threonyl-D-α-aminobutyryl-L-prolyl-N-methyl-L-phenylalanyl-4-oxo-L-pipecoloyl-L-2-phenylglycine in which the carboxy group of the 2-phenylglycine moiety has undergone formal intramolecular condensation with the hydroxy group of the N-(3-hydroxypicolinoyl)-L-threonyl to give the corresponding 19-membered ring lactone. It is one of the two major components of the antibacterial drug virginiamycin, produced by Streptomyces virginiae, S. loidensis, S. mitakaensis, S. pristina-spiralis, S. ostreogriseus, and others. http://purl.obolibrary.org/obo/CHEBI_471744 imipenem http://purl.obolibrary.org/obo/CHEBI_88225 beta-lactam antibiotic allergen A broad-spectrum, intravenous β-lactam antibiotic of the carbapenem subgroup. http://purl.obolibrary.org/obo/CHEBI_474180 caspofungin http://purl.obolibrary.org/obo/CHEBI_72588 semisynthetic derivative A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-β-D-glucan, an integral component of the fungal cell wall. http://purl.obolibrary.org/obo/CHEBI_47518 (2S,4R)-ketoconazole http://purl.obolibrary.org/obo/CHEBI_86411 cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2S,4R)-configuration. http://purl.obolibrary.org/obo/CHEBI_47519 ketoconazole http://purl.obolibrary.org/obo/CHEBI_87069 imidazole antifungal drug A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-ketoconazole. http://purl.obolibrary.org/obo/CHEBI_48080 brefeldin A http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity. http://purl.obolibrary.org/obo/CHEBI_4811 epoxiconazole http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide A racemate composed of equimolar amounts of (2S,3R)- and (2R,3S)-epoxiconazole. A broad-spectrum fungicide for control of diseases caused by Ascomycetes, Basidiomycetes and Deuteromycetes. Epoxiconazole is moderately toxic to birds, honeybees, earthworms and most aquatic organisms. http://purl.obolibrary.org/obo/CHEBI_48121 polyene http://purl.obolibrary.org/obo/CHEBI_33641 olefin An olefin that contains more than one carbon-carbon double bond. http://purl.obolibrary.org/obo/CHEBI_48336 (2R,4S)-ketoconazole http://purl.obolibrary.org/obo/CHEBI_86411 cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration. http://purl.obolibrary.org/obo/CHEBI_48339 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine http://purl.obolibrary.org/obo/CHEBI_46848 N-arylpiperazine A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively. http://purl.obolibrary.org/obo/CHEBI_48359 protophilic solvent http://purl.obolibrary.org/obo/CHEBI_48354 polar solvent Solvent that is capable of acting as a hydron (proton) acceptor. http://purl.obolibrary.org/obo/CHEBI_48377 imidic acid http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative Compounds derived from oxoacids RkE(=O)l(OH)m (l ≠ 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH). http://purl.obolibrary.org/obo/CHEBI_48379 isourea http://purl.obolibrary.org/obo/CHEBI_48378 carboximidic acid A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives. http://purl.obolibrary.org/obo/CHEBI_48960 bis(azo) compound http://purl.obolibrary.org/obo/CHEBI_37533 azo compound Any azo compound containing two ‒N=N‒ groups. http://purl.obolibrary.org/obo/CHEBI_59676 nystatins http://purl.obolibrary.org/obo/CHEBI_48121 polyene A class of polyene antifungal antibiotics produced by Streptomyces noursei, and other Streptomyces species. http://purl.obolibrary.org/obo/CHEBI_59999 chemical substance http://purl.obolibrary.org/obo/CHEBI_24431 chemical entity A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types. http://purl.obolibrary.org/obo/CHEBI_600520 micafungin http://purl.obolibrary.org/obo/CHEBI_87113 antibiotic antifungal drug A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-β-D-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy. http://purl.obolibrary.org/obo/CHEBI_64133 EC 2.5.1.58 (protein farnesyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76663 EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group. http://purl.obolibrary.org/obo/CHEBI_64383 pentamidinium(2+) http://purl.obolibrary.org/obo/CHEBI_77718 carboxamidinium ion A carboxamidinium ion obtained by protonation of both amindino groups of pentamidine. http://purl.obolibrary.org/obo/CHEBI_7489 neamine http://purl.obolibrary.org/obo/CHEBI_53628 2,6-dideoxy-alpha-D-glucoside 2-Deoxy-D-streptamine glycosylated at the 4-oxygen with a 6-amino-α-D-glucosaminyl group. http://purl.obolibrary.org/obo/CHEBI_75954 vancomycin aglycone zwitterion http://purl.obolibrary.org/obo/CHEBI_60466 peptide zwitterion A peptide zwitterion obtained by transfer of a proton from the carboxy to the amino group of vancomycin aglycone. http://purl.obolibrary.org/obo/CHEBI_77718 carboxamidinium ion http://purl.obolibrary.org/obo/CHEBI_35286 iminium ion Any iminium ion resulting from the protonation of a carboxamidine. http://purl.obolibrary.org/obo/CHEBI_77981 vancomycin aglycone(1-) http://purl.obolibrary.org/obo/CHEBI_60334 peptide anion A peptide anion that is the conjugate base of vancomycin aglycone and the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_79093 EC 1.11.2.2 (myeloperoxidase) inhibitor http://purl.obolibrary.org/obo/CHEBI_79092 EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor An EC 1.11.2.* (oxidoreductase with H2O2 as acceptor, incorporating 1 O atom into product) inhibitor that interferes with the action of myeloperoxidase (EC 1.11.2.2). http://purl.obolibrary.org/obo/CHEBI_7934 paromomycin http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-α-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. http://purl.obolibrary.org/obo/CHEBI_8232 piperacillin http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen A penicillin in which the substituent at position 6 of the penam ring is a 2-[(4-ethyl-2,3-dioxopiperazin-1-yl)carboxamido]-2-phenylacetamido group. http://purl.obolibrary.org/obo/CHEBI_83759 (2S,3R)-epoxiconazole http://purl.obolibrary.org/obo/CHEBI_83758 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole The (2S,3R)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole. http://purl.obolibrary.org/obo/CHEBI_83761 (2R,3S)-epoxiconazole http://purl.obolibrary.org/obo/CHEBI_83758 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole The (2R,3S)-stereoisomer of 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole. http://purl.obolibrary.org/obo/CHEBI_86411 cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine http://purl.obolibrary.org/obo/CHEBI_48339 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine Either of the two diastereoisomers of 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the imidazol-1-ylmethyl group and the aryloxymethyl group are in a cis relationship to each other - i.e. they are both on the same side of the plane of the dioxolane ring. The antifungal drug ketoconazole is a racemic mixture of the two cis diastereoisomers. http://purl.obolibrary.org/obo/CHEBI_87066 carbanilate fungicide http://purl.obolibrary.org/obo/CHEBI_87061 carbamate fungicide Any carbamate fungicide that has a phenyl or substituted-phenyl group attached to the nitrogen of the carbamate group. http://purl.obolibrary.org/obo/CHEBI_9168 sirolimus http://purl.obolibrary.org/obo/CHEBI_145565 macrolide lactam A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent. http://purl.obolibrary.org/obo/CHEBI_9215 spectinomycin http://purl.obolibrary.org/obo/CHEBI_146295 pyranobenzodioxin A pyranobenzodioxin and antibiotic that is active against gram-negative bacteria and used (as its dihydrochloride pentahydrate) to treat gonorrhea. It is produced by the bacterium Streptomyces spectabilis. http://purl.obolibrary.org/obo/CHEBI_9997 pristinamycin IIA http://purl.obolibrary.org/obo/CHEBI_140326 tertiary carboxamide A macrolide that is (together with pristinamycin IA) a component of pristinamycin, an oral streptogramin antibiotic produced by Streptomyces pristinaespiralis. Pristinamycin exhibits bactericidal activity against Gram positive organisms including methicillin-resistant Staphylococcus aureus. http://purl.obolibrary.org/obo/CHEBI_51208 mecillinam http://purl.obolibrary.org/obo/CHEBI_17334 penicillin A penicillin in which the 6β substituent is [(azepan-1-yl)methylidene]amino; an extended-spectrum penicillin antibiotic that binds specifically to penicillin binding protein 2 (PBP2), and is only considered to be active against Gram-negative bacteria. http://purl.obolibrary.org/obo/CHEBI_51721 alpha,beta-unsaturated ketone http://purl.obolibrary.org/obo/CHEBI_17087 ketone A ketone of general formula R1R2C=CR3‒C(=O)R4 (R4 ≠ H) or R1C≡C‒C(=O)R2 (R2 ≠ H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the α,β position. http://purl.obolibrary.org/obo/CHEBI_51750 alpha,beta-unsaturated carboxylic acid amide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A monocarboxylic amide of general formula R1R2C=CR3‒C(=O)NR4R5 or R1C≡C‒C(=O)NR2R3 in which the amide C=O function is conjugated to an unsaturated C-C bond at the α,β position. http://purl.obolibrary.org/obo/CHEBI_5195 furazolidone http://purl.obolibrary.org/obo/CHEBI_38329 oxazolidines A member of the class of oxazolidines that is 1,3-oxazolidin-2-one in which the hydrogen attached to the nitrogen is replaced by an N-{[(5-nitro-2-furyl)methylene]amino} group. It has antibacterial and antiprotozoal properties, and is used in the treatment of giardiasis and cholera. http://purl.obolibrary.org/obo/CHEBI_52492 mancozeb http://purl.obolibrary.org/obo/CHEBI_60004 mixture A mixture composed from maneb and zineb, which is used as a broad-spectrum contact fungicide. http://purl.obolibrary.org/obo/CHEBI_52497 maneb http://purl.obolibrary.org/obo/CHEBI_60027 polymer A polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand. An agrochemical fungicide, it is used to control a variety of diseases including blight, leaf spot, rust, downy mildew and scab. http://purl.obolibrary.org/obo/CHEBI_52498 zineb http://purl.obolibrary.org/obo/CHEBI_33839 macromolecule A polymeric complex of zinc with the ethylene bis(dithiocarbamate) anionic ligand. Formerly used as an agricultural fungicide for the control of downy mildews and rusts, its use is no longer permitted in the US or the EU. http://purl.obolibrary.org/obo/CHEBI_52549 sordarin http://purl.obolibrary.org/obo/CHEBI_24400 glycoside An antifungal metabolite of Sordaria araneosa that inhibits protein synthesis. It has a tetracyclic diterpene glycoside structure. http://purl.obolibrary.org/obo/CHEBI_52646 leptomycin B http://purl.obolibrary.org/obo/CHEBI_140345 hydroxy polyunsaturated fatty acid A leptomycin having a (2E,10E,12E,16Z,18E)-double bond configuration as well as an ethyl substituent at position 17. http://purl.obolibrary.org/obo/CHEBI_52651 leptomycin http://purl.obolibrary.org/obo/CHEBI_26208 polyunsaturated fatty acid A complex, very long chain, polyunsaturated fatty acid whose core structure comprises 8-oxononadeca-2,10,12,16,18-pentaenoic acid having methyl substituents at positions 3, 5, 7, 9, 11 and 15 and a 3,6-dihydropyran-6-one-2-yl group at position 19. http://purl.obolibrary.org/obo/CHEBI_6827 methicillin http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen A penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 2,6-dimethoxybenzoyl group. http://purl.obolibrary.org/obo/CHEBI_77308 ethylenebis(dithiocarbamate) http://purl.obolibrary.org/obo/CHEBI_84292 dithiocarbamate anions A member of the class of dithiocarbamate anions resulting from the deprotonation of both of the dithiocarbamic acid moieties of ethylenebis(dithiocarbamic acid). The major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_9587 ticarcillin http://purl.obolibrary.org/obo/CHEBI_88187 penicillin allergen A penicillin compound having a 6β-[(2R)-2-carboxy-2-thiophen-3-ylacetyl]amino side-group. http://purl.obolibrary.org/obo/CHEBI_7451 naftifine http://purl.obolibrary.org/obo/CHEBI_87127 allylamine antifungal drug A tertiary amine in which the nitrogen is substituted by methyl, α-naphthylmethyl, and (1E)-cinnamyl groups. It is used (usually as its hydrochloride salt) for the treatment of fungal skin infections. http://purl.obolibrary.org/obo/CHEBI_7507 neomycin http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic A broad-spectrum highly toxic antibiotic or mixture of antibiotics produced by a streptomyces (Streptomyces fradiae) and used medically especially to treat local infections. http://purl.obolibrary.org/obo/CHEBI_75283 miltefosine http://purl.obolibrary.org/obo/CHEBI_16247 phospholipid A phospholipid that is the hexadecyl monoester of phosphocholine. http://purl.obolibrary.org/obo/CHEBI_87127 allylamine antifungal drug http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound An organonitrogen compound that contains an amino group that is attached to a carbon which is itself attached to an olefinic carbon and which has been used as an antifungal drug. http://purl.obolibrary.org/obo/CHEBI_87835 framycetin(6+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the six amino groups of framycetin; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_86420 imidazole antifungal agent http://purl.obolibrary.org/obo/CHEBI_24780 imidazoles A compound that has significant antifungal properties whose structure contains an imidazole moiety. http://purl.obolibrary.org/obo/CHEBI_86426 triazole antifungal agent http://purl.obolibrary.org/obo/CHEBI_35727 triazoles A member of the class of triazole that has significant antifungal properties. http://purl.obolibrary.org/obo/CHEBI_8653 pyocyanine http://purl.obolibrary.org/obo/CHEBI_35285 iminium betaine An iminium betaine that is 5-methylphenazin-5-ium which is substituted at position 1 by an oxidanidyl group. An antibiotic pigment produced by Pseudomonas aeruginosa. http://purl.obolibrary.org/obo/CHEBI_8674 pyrimethanil http://purl.obolibrary.org/obo/CHEBI_50995 secondary amino compound A member of the class of aminopyrimidines that is N-phenylpyrimidin-2-amine carrying two additional methyl substituents at positions 4 and 6. A fungicide used to control grey mould on fruit, vegetables and ornamentals as well as leaf scab on pome fruit. Also commonly employed to control Botrytis cinerea throughout the winemaking process in grapes, must, fermenting must and wine. http://purl.obolibrary.org/obo/GO_0004518 nuclease activity http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalysis of the cleavage of ester linkages within nucleic acids. http://purl.obolibrary.org/obo/GO_0004536 DNA nuclease activity http://purl.obolibrary.org/obo/GO_0140097 catalytic activity, acting on DNA Catalysis of the cleavage of ester linkages within deoxyribonucleic acid. http://purl.obolibrary.org/obo/GO_0004568 chitinase activity http://purl.obolibrary.org/obo/GO_0004553 hydrolase activity, hydrolyzing O-glycosyl compounds Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. http://purl.obolibrary.org/obo/GO_0004925 prolactin receptor activity http://purl.obolibrary.org/obo/GO_0004896 cytokine receptor activity Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004977 melanocortin receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with melanocortin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004978 corticotropin receptor activity http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity Combining with corticotropin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0005000 vasopressin receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with vasopressin to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0005172 vascular endothelial growth factor receptor binding http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding Binding to a vascular endothelial growth factor receptor. http://purl.obolibrary.org/obo/GO_0005173 stem cell factor receptor binding http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding Binding to a stem cell factor receptor (SCFR), a type III transmembrane kinase receptor. http://purl.obolibrary.org/obo/GO_0005215 transporter activity http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, accross or in between cells. http://purl.obolibrary.org/obo/GO_0005275 amine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of amines, including polyamines, from one side of a membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group. http://purl.obolibrary.org/obo/GO_0005277 acetylcholine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_1901375 acetate ester transmembrane transporter activity Enables the transfer of acetylcholine from one side of a membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0005313 L-glutamate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015179 L-amino acid transmembrane transporter activity Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0005319 lipid transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Enables the directed movement of lipids into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/GO_0005326 neurotransmitter transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/GO_0005496 steroid binding http://purl.obolibrary.org/obo/GO_0008289 lipid binding Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene. http://purl.obolibrary.org/obo/GO_0005518 collagen binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0005539 glycosaminoglycan binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues. http://purl.obolibrary.org/obo/GO_0005540 hyaluronic acid binding http://purl.obolibrary.org/obo/GO_0005539 glycosaminoglycan binding Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. http://purl.obolibrary.org/obo/GO_0005575 cellular_component http://purl.obolibrary.org/obo/BFO_0000040 material entity A location, relative to cellular compartments and structures, occupied by a macromolecular machine. There are three types of cellular components described in the gene ontology: (1) the cellular anatomical entity where a gene product carries out a molecular function (e.g., plasma membrane, cytoskeleton) or membrane-enclosed compartments (e.g., mitochondrion); (2) virion components, where viral proteins act, and (3) the stable macromolecular complexes of which gene product are parts (e.g., the clathrin complex). http://purl.obolibrary.org/obo/GO_0005576 extracellular region http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0005577 fibrinogen complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. http://purl.obolibrary.org/obo/GO_0005581 collagen trimer http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. http://purl.obolibrary.org/obo/GO_0005583 fibrillar collagen trimer http://purl.obolibrary.org/obo/GO_0005581 collagen trimer Any triple helical collagen trimer that forms fibrils. http://purl.obolibrary.org/obo/GO_0005585 collagen type II trimer http://purl.obolibrary.org/obo/GO_0005583 fibrillar collagen trimer A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils. http://purl.obolibrary.org/obo/GO_0005587 collagen type IV trimer http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. http://purl.obolibrary.org/obo/GO_0005604 basement membrane http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. http://purl.obolibrary.org/obo/GO_0005614 interstitial matrix http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens. http://purl.obolibrary.org/obo/GO_0005615 extracellular space http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. http://purl.obolibrary.org/obo/GO_0005635 nuclear envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer that encloses the nucleus, separating its contents from the cytoplasm. It consists of an inner and outer nuclear membrane, with an intermembrane space (20-40 nm wide, also called the perinuclear space) between them. The envelope is supported by the nuclear lamina and contains nuclear pore complexes, which regulate molecular transport. http://purl.obolibrary.org/obo/GO_0005640 nuclear outer membrane http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. http://purl.obolibrary.org/obo/GO_0005677 chromatin silencing complex http://purl.obolibrary.org/obo/GO_0140513 nuclear protein-containing complex Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing. http://purl.obolibrary.org/obo/GO_0005730 nucleolus http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome. http://purl.obolibrary.org/obo/GO_0005740 mitochondrial envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0005759 mitochondrial matrix http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation. http://purl.obolibrary.org/obo/GO_0005761 mitochondrial ribosome http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes. http://purl.obolibrary.org/obo/GO_0005765 lysosomal membrane http://purl.obolibrary.org/obo/GO_0098852 lytic vacuole membrane The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. http://purl.obolibrary.org/obo/GO_0005766 primary lysosome http://purl.obolibrary.org/obo/GO_0005764 lysosome A lysosome before it has fused with a vesicle or vacuole. http://purl.obolibrary.org/obo/GO_0005794 Golgi apparatus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. http://purl.obolibrary.org/obo/GO_0005798 Golgi-associated vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. http://purl.obolibrary.org/obo/GO_0005811 lipid droplet http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. http://purl.obolibrary.org/obo/GO_0005874 microtubule http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. http://purl.obolibrary.org/obo/GO_0005879 axonemal microtubule http://purl.obolibrary.org/obo/GO_0005881 cytoplasmic microtubule A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. http://purl.obolibrary.org/obo/GO_0005880 nuclear microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in the nucleus of a cell. http://purl.obolibrary.org/obo/GO_0005884 actin filament http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. http://purl.obolibrary.org/obo/GO_0005902 microvillus http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. http://purl.obolibrary.org/obo/GO_0005903 brush border http://purl.obolibrary.org/obo/GO_0098862 cluster of actin-based cell projections The dense covering of microvilli on the apical surface of an epithelial cell in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell. http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction http://purl.obolibrary.org/obo/GO_0070161 anchoring junction A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. http://purl.obolibrary.org/obo/GO_0005923 bicellular tight junction http://purl.obolibrary.org/obo/GO_0070160 tight junction An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. http://purl.obolibrary.org/obo/GO_0005929 cilium http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. http://purl.obolibrary.org/obo/GO_0005930 axoneme http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/GO_0005938 cell cortex http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. http://purl.obolibrary.org/obo/GO_0005975 carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006023 aminoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006024 glycosaminoglycan biosynthetic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0006026 aminoglycan catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. http://purl.obolibrary.org/obo/GO_0006027 glycosaminoglycan catabolic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0006033 chitin localization http://purl.obolibrary.org/obo/GO_0033037 polysaccharide localization A process in which chitin is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0006066 alcohol metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0006109 regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. http://purl.obolibrary.org/obo/GO_0006139 nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0006309 apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments. http://purl.obolibrary.org/obo/GO_0006338 chromatin remodeling http://purl.obolibrary.org/obo/GO_0006325 chromatin organization A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. http://purl.obolibrary.org/obo/GO_0006399 tRNA metabolic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established. http://purl.obolibrary.org/obo/GO_0006403 RNA localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization A process in which RNA is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0006404 RNA import into nucleus http://purl.obolibrary.org/obo/GO_0051170 import into nucleus The import of RNA from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0006405 RNA export from nucleus http://purl.obolibrary.org/obo/GO_0051168 nuclear export The directed movement of RNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0006409 tRNA export from nucleus http://purl.obolibrary.org/obo/GO_0051031 tRNA transport The directed movement of tRNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0006417 regulation of translation http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0006446 regulation of translational initiation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate, extent or accuracy of translational elongation. http://purl.obolibrary.org/obo/GO_0006449 regulation of translational termination http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0006516 glycoprotein catabolic process http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0006518 peptide metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. http://purl.obolibrary.org/obo/GO_0006536 glutamate metabolic process http://purl.obolibrary.org/obo/GO_0009064 glutamine family amino acid metabolic process The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0006537 glutamate biosynthetic process http://purl.obolibrary.org/obo/GO_0043650 dicarboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0006538 L-glutamate catabolic process http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of L-glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0006544 glycine metabolic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways involving glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0006545 glycine biosynthetic process http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0006546 glycine catabolic process http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0006553 lysine metabolic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid. http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0006611 protein export from nucleus http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. http://purl.obolibrary.org/obo/GO_0006643 membrane lipid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane. http://purl.obolibrary.org/obo/GO_0006694 steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. http://purl.obolibrary.org/obo/GO_0006706 steroid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0006714 sesquiterpenoid metabolic process http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units. http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0006721 terpenoid metabolic process http://purl.obolibrary.org/obo/GO_0006720 isoprenoid metabolic process The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups. http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus. http://purl.obolibrary.org/obo/GO_0006796 phosphate-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0006793 phosphorus metabolic process The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. http://purl.obolibrary.org/obo/GO_0006810 transport http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or a transporter complex, a pore or a motor protein. http://purl.obolibrary.org/obo/GO_0006811 monoatomic ion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a monoatomic ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0006835 dicarboxylic acid transport http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006858 extracellular transport http://purl.obolibrary.org/obo/GO_0006810 transport The transport of substances that occurs outside cells. http://purl.obolibrary.org/obo/GO_0006860 extracellular amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed extracellular movement of amino acids. http://purl.obolibrary.org/obo/GO_0006887 exocytosis http://purl.obolibrary.org/obo/GO_0032940 secretion by cell A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for example of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. http://purl.obolibrary.org/obo/GO_0006892 post-Golgi vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0048193 Golgi vesicle transport The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. http://purl.obolibrary.org/obo/GO_0006893 Golgi to plasma membrane transport http://purl.obolibrary.org/obo/GO_0098876 vesicle-mediated transport to the plasma membrane The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. http://purl.obolibrary.org/obo/GO_0006896 Golgi to vacuole transport http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport The directed movement of substances from the Golgi to the vacuole. http://purl.obolibrary.org/obo/GO_0006897 endocytosis http://purl.obolibrary.org/obo/GO_0098657 import into cell A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a part of the plasma membrane to form a new membrane-bounded vesicle. http://purl.obolibrary.org/obo/GO_0006900 vesicle budding from membrane http://purl.obolibrary.org/obo/GO_0016050 vesicle organization The evagination of a membrane, resulting in formation of a vesicle. http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. http://purl.obolibrary.org/obo/GO_0006906 vesicle fusion http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion Fusion of the membrane of a transport vesicle with its target membrane. http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis. http://purl.obolibrary.org/obo/GO_0006935 chemotaxis http://purl.obolibrary.org/obo/GO_0042330 taxis The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0006936 muscle contraction http://purl.obolibrary.org/obo/GO_0003012 muscle system process A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process Any process that modulates the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0006939 smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006936 muscle contraction A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. http://purl.obolibrary.org/obo/GO_0006942 regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction Any process that modulates the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0006996 organelle organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0006998 nuclear envelope organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. http://purl.obolibrary.org/obo/GO_0007000 nucleolus organization http://purl.obolibrary.org/obo/GO_0006997 nucleus organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus. http://purl.obolibrary.org/obo/GO_0007006 mitochondrial membrane organization http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion. http://purl.obolibrary.org/obo/GO_0007008 outer mitochondrial membrane organization http://purl.obolibrary.org/obo/GO_0007006 mitochondrial membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane. http://purl.obolibrary.org/obo/GO_0007015 actin filament organization http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. http://purl.obolibrary.org/obo/GO_0007019 microtubule depolymerization http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization The removal of tubulin heterodimers from one or both ends of a microtubule. http://purl.obolibrary.org/obo/GO_0007020 microtubule nucleation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). http://purl.obolibrary.org/obo/GO_0007026 negative regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1902904 negative regulation of supramolecular fiber organization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol. http://purl.obolibrary.org/obo/GO_0007027 negative regulation of axonemal microtubule depolymerization http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme. http://purl.obolibrary.org/obo/GO_0007028 cytoplasm organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0007030 Golgi organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances into, out of or within a vacuole. http://purl.obolibrary.org/obo/GO_0007039 protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. http://purl.obolibrary.org/obo/GO_0007041 lysosomal transport http://purl.obolibrary.org/obo/GO_0007034 vacuolar transport The directed movement of substances into, out of or within a lysosome. http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation http://purl.obolibrary.org/obo/GO_0022402 cell cycle process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_0007076 mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0007077 mitotic nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The mitotic cell cycle process in which the controlled partial or complete breakdown of the nuclear membranes during occurs during mitosis. http://purl.obolibrary.org/obo/GO_0007088 regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division Any process that modulates the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0007113 endomitotic cell cycle http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell. http://purl.obolibrary.org/obo/GO_0007134 meiotic telophase I http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. http://purl.obolibrary.org/obo/GO_0007135 meiosis II http://purl.obolibrary.org/obo/GO_0061983 meiosis II cell cycle process The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II. http://purl.obolibrary.org/obo/GO_0007143 female meiotic nuclear division http://purl.obolibrary.org/obo/GO_0140013 meiotic nuclear division A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. http://purl.obolibrary.org/obo/GO_0007147 female meiosis II http://purl.obolibrary.org/obo/GO_0007143 female meiotic nuclear division The cell cycle process in which the second meiotic division occurs in the female germline. http://purl.obolibrary.org/obo/GO_0007159 leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of a leukocyte to another cell via adhesion molecules. http://purl.obolibrary.org/obo/GO_0007162 negative regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0007213 G protein-coupled acetylcholine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by a ligand binding to an acetylcholine receptor on the surface of a target cell, and ends with regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0007214 gamma-aminobutyric acid signaling pathway http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell. http://purl.obolibrary.org/obo/GO_0007215 glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0007216 G protein-coupled glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0007218 neuropeptide signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling The vesicular release of classical neurotransmitter molecules from a presynapse, across a chemical synapse, the subsequent activation of neurotransmitter receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0007272 ensheathment of neurons http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment. http://purl.obolibrary.org/obo/GO_0007276 gamete generation http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. http://purl.obolibrary.org/obo/GO_0007281 germ cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. http://purl.obolibrary.org/obo/GO_0007292 female gamete generation http://purl.obolibrary.org/obo/GO_0007276 gamete generation Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. http://purl.obolibrary.org/obo/GO_0007293 germarium-derived egg chamber formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007308 oocyte construction http://purl.obolibrary.org/obo/GO_0048469 cell maturation The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0007338 single fertilization http://purl.obolibrary.org/obo/GO_0009566 fertilization The union of male and female gametes to form a zygote. http://purl.obolibrary.org/obo/GO_0007343 egg activation http://purl.obolibrary.org/obo/GO_0001775 cell activation The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm. http://purl.obolibrary.org/obo/GO_0007346 regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates the rate or extent of progress through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0007350 blastoderm segmentation http://purl.obolibrary.org/obo/GO_0035282 segmentation The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo. http://purl.obolibrary.org/obo/GO_0007399 nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0007406 negative regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_1902692 regulation of neuroblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. http://purl.obolibrary.org/obo/GO_0007407 neuroblast activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0007409 axonogenesis http://purl.obolibrary.org/obo/GO_0048812 neuron projection morphogenesis De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells. http://purl.obolibrary.org/obo/GO_0007416 synapse assembly http://purl.obolibrary.org/obo/GO_0050808 synapse organization The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional). http://purl.obolibrary.org/obo/GO_0007417 central nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0007418 ventral midline development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. http://purl.obolibrary.org/obo/GO_0007420 brain development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). http://purl.obolibrary.org/obo/GO_0007422 peripheral nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. http://purl.obolibrary.org/obo/GO_0007439 ectodermal digestive tract development http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm. http://purl.obolibrary.org/obo/GO_0007440 foregut morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the foregut are generated and organized. http://purl.obolibrary.org/obo/GO_0007498 mesoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. http://purl.obolibrary.org/obo/GO_0007506 gonadal mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. http://purl.obolibrary.org/obo/GO_0007517 muscle organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. http://purl.obolibrary.org/obo/GO_0007528 neuromuscular junction development http://purl.obolibrary.org/obo/GO_0050808 synapse organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction. http://purl.obolibrary.org/obo/GO_0007530 sex determination http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction Any process that establishes and transmits the specification of sexual status of an individual organism. http://purl.obolibrary.org/obo/GO_0007548 sex differentiation http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The establishment of the sex of an organism by physical differentiation. http://purl.obolibrary.org/obo/GO_0007565 female pregnancy http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. http://purl.obolibrary.org/obo/GO_0007566 embryo implantation http://purl.obolibrary.org/obo/GO_0022414 reproductive process Attachment of the blastocyst to the uterine lining. http://purl.obolibrary.org/obo/GO_0007586 digestion http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0007589 body fluid secretion http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels The controlled release of a fluid by a cell or tissue in an animal. http://purl.obolibrary.org/obo/GO_0007600 sensory perception http://purl.obolibrary.org/obo/GO_0050877 nervous system process The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0007601 visual perception http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. http://purl.obolibrary.org/obo/GO_0007605 sensory perception of sound http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0007611 learning or memory http://purl.obolibrary.org/obo/GO_0007610 behavior The acquisition and processing of information and/or the storage and retrieval of this information over time. http://purl.obolibrary.org/obo/GO_0007613 memory http://purl.obolibrary.org/obo/GO_0007611 learning or memory The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). http://purl.obolibrary.org/obo/GO_0008015 blood circulation http://purl.obolibrary.org/obo/GO_0003013 circulatory system process The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. http://purl.obolibrary.org/obo/GO_0008017 microtubule binding http://purl.obolibrary.org/obo/GO_0015631 tubulin binding Binding to a microtubule, a filament composed of tubulin monomers. http://purl.obolibrary.org/obo/GO_0008028 monocarboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity Enables the transfer of monocarboxylic acids from one side of a membrane to the other. A monocarboxylic acid is an organic acid with one COOH group. http://purl.obolibrary.org/obo/GO_0008053 mitochondrial fusion http://purl.obolibrary.org/obo/GO_0048284 organelle fusion Merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0008061 chitin binding http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. http://purl.obolibrary.org/obo/GO_0008066 glutamate receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0008078 mesodermal cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The orderly movement of mesodermal cells from one site to another. http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule The directed movement of organelles or molecules along microtubules in neuron projections. http://purl.obolibrary.org/obo/GO_0008089 anterograde axonal transport http://purl.obolibrary.org/obo/GO_0098930 axonal transport The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons. http://purl.obolibrary.org/obo/GO_0008090 retrograde axonal transport http://purl.obolibrary.org/obo/GO_0098930 axonal transport The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons. http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization http://purl.obolibrary.org/obo/GO_0070727 cellular macromolecule localization Any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0008152 metabolic process http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process consisting of the biochemical pathways by which a living organism transforms chemical substances. This includes including anabolism (biosynthetic process) and catabolism (catabolic process). Metabolic processes includes the transformation of small molecules, as well macromolecular processes such as DNA repair and replication, protein synthesis and degradation. http://purl.obolibrary.org/obo/GO_0008202 steroid metabolic process http://purl.obolibrary.org/obo/GO_0006629 lipid metabolic process The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0008291 acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0008354 germ cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. http://purl.obolibrary.org/obo/GO_0008406 gonad development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. http://purl.obolibrary.org/obo/GO_0008504 monoamine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0008641 ubiquitin-like modifier activating enzyme activity http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond. http://purl.obolibrary.org/obo/GO_0008643 carbohydrate transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0009067 aspartate family amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine. http://purl.obolibrary.org/obo/GO_0009070 serine family amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_1901607 alpha-amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine. http://purl.obolibrary.org/obo/GO_0009084 glutamine family amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. http://purl.obolibrary.org/obo/GO_0009100 glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0009101 glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0009112 nucleobase metabolic process http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine. http://purl.obolibrary.org/obo/GO_0009416 response to light stimulus http://purl.obolibrary.org/obo/GO_0009314 response to radiation Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. http://purl.obolibrary.org/obo/GO_0009566 fertilization http://purl.obolibrary.org/obo/GO_0022414 reproductive process The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009584 detection of visible light http://purl.obolibrary.org/obo/GO_0009583 detection of light stimulus The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. http://purl.obolibrary.org/obo/GO_0009712 catechol-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0018958 phenol-containing compound metabolic process The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. http://purl.obolibrary.org/obo/GO_0010160 formation of animal organ boundary http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. http://purl.obolibrary.org/obo/GO_0010256 endomembrane system organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. http://purl.obolibrary.org/obo/GO_0010324 membrane invagination http://purl.obolibrary.org/obo/GO_0061024 membrane organization The infolding of a membrane. http://purl.obolibrary.org/obo/GO_0010469 regulation of signaling receptor activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010565 regulation of ketone metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0010566 regulation of ketone biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. http://purl.obolibrary.org/obo/GO_0010608 post-transcriptional regulation of gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript. http://purl.obolibrary.org/obo/GO_0010629 negative regulation of gene expression http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0010876 lipid localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a lipid is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0010970 transport along microtubule http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. http://purl.obolibrary.org/obo/GO_0012505 endomembrane system http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. http://purl.obolibrary.org/obo/GO_0014902 myotube differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0015031 protein transport http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015075 monoatomic ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an ion from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015172 acidic amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have side chains with a negative charge at pH 7.3. http://purl.obolibrary.org/obo/GO_0015185 gamma-aminobutyric acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA). http://purl.obolibrary.org/obo/GO_0015631 tubulin binding http://purl.obolibrary.org/obo/GO_0008092 cytoskeletal protein binding Binding to monomeric or multimeric forms of tubulin, including microtubules. http://purl.obolibrary.org/obo/GO_0015671 oxygen transport http://purl.obolibrary.org/obo/GO_0015669 gas transport The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015718 monocarboxylic acid transport http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015837 amine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015844 monoamine transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. http://purl.obolibrary.org/obo/GO_0015851 nucleobase transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015931 nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015932 nucleobase-containing compound transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0016020 membrane http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A lipid bilayer along with all the proteins and protein complexes embedded in it and attached to it. http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0016043 cellular component organization http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0016106 sesquiterpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0016114 terpenoid biosynthetic process The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units. http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. http://purl.obolibrary.org/obo/GO_0016310 phosphorylation http://purl.obolibrary.org/obo/GO_0006796 phosphate-containing compound metabolic process The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. http://purl.obolibrary.org/obo/GO_0016325 oocyte microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0030951 establishment or maintenance of microtubule cytoskeleton polarity Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances or organelles within the cytosol. http://purl.obolibrary.org/obo/GO_0016595 glutamate binding http://purl.obolibrary.org/obo/GO_0016597 amino acid binding Binding to glutamate, the anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0016798 hydrolase activity, acting on glycosyl bonds http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity Catalysis of the hydrolysis of any glycosyl bond. http://purl.obolibrary.org/obo/GO_0016907 G protein-coupled acetylcholine receptor activity http://purl.obolibrary.org/obo/GO_0099528 G protein-coupled neurotransmitter receptor activity Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0016917 GABA receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0018958 phenol-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0019098 reproductive behavior http://purl.obolibrary.org/obo/GO_0007610 behavior The specific behavior of an organism that is associated with reproduction. http://purl.obolibrary.org/obo/GO_0019218 regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0019219 regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving a protein. Includes protein modification. http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the cell. http://purl.obolibrary.org/obo/GO_0019747 regulation of isoprenoid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids. http://purl.obolibrary.org/obo/GO_0019748 secondary metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. http://purl.obolibrary.org/obo/GO_0019751 polyol metabolic process http://purl.obolibrary.org/obo/GO_0006066 alcohol metabolic process The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y = Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein. http://purl.obolibrary.org/obo/GO_0021700 developmental maturation http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A cellular process that results in the breakdown of a cellular component. http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of a gland are generated and organized. http://purl.obolibrary.org/obo/GO_0022626 cytosolic ribosome http://purl.obolibrary.org/obo/GO_0005840 ribosome A ribosome located in the cytosol. http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0030017 sarcomere http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly http://purl.obolibrary.org/obo/GO_0030030 cell projection organization Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0030054 cell junction http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0030246 carbohydrate binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. http://purl.obolibrary.org/obo/GO_0030262 apoptotic nuclear changes http://purl.obolibrary.org/obo/GO_0006921 cellular component disassembly involved in execution phase of apoptosis Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. http://purl.obolibrary.org/obo/GO_0030594 neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0030936 transmembrane collagen trimer http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex Any collagen trimer that passes through a lipid bilayer membrane. http://purl.obolibrary.org/obo/GO_0030990 intraciliary transport particle http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. http://purl.obolibrary.org/obo/GO_0031012 extracellular matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. http://purl.obolibrary.org/obo/GO_0031109 microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. http://purl.obolibrary.org/obo/GO_0031111 negative regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1901879 regulation of protein depolymerization Any process that modulates the frequency, rate or extent of microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0031345 negative regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031406 carboxylic acid binding http://purl.obolibrary.org/obo/GO_0043177 organic acid binding Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0031965 nuclear membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. http://purl.obolibrary.org/obo/GO_0031966 mitochondrial membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. http://purl.obolibrary.org/obo/GO_0031967 organelle envelope http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane http://purl.obolibrary.org/obo/GO_0019867 outer membrane The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope. http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen. http://purl.obolibrary.org/obo/GO_0032042 mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The chemical reactions and pathways involving mitochondrial DNA. http://purl.obolibrary.org/obo/GO_0032350 regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/GO_0032365 intracellular lipid transport http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032368 regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell http://purl.obolibrary.org/obo/GO_0045185 maintenance of protein location Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0032787 monocarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a macromolecule is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033037 polysaccharide localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization Any process in which a polysaccharide is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0033218 amide binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/GO_0033238 regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. http://purl.obolibrary.org/obo/GO_0034308 primary alcohol metabolic process http://purl.obolibrary.org/obo/GO_0006066 alcohol metabolic process The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. http://purl.obolibrary.org/obo/GO_0034309 primary alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0046165 alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. http://purl.obolibrary.org/obo/GO_0034329 cell junction assembly http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein transports or maintains the localization of another protein to the nucleus. http://purl.obolibrary.org/obo/GO_0034655 nucleobase-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0034765 regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035082 axoneme assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_0035240 dopamine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine. http://purl.obolibrary.org/obo/GO_0035265 organ growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. http://purl.obolibrary.org/obo/GO_0035272 exocrine system development http://purl.obolibrary.org/obo/GO_0048731 system development Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. http://purl.obolibrary.org/obo/GO_0035295 tube development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. http://purl.obolibrary.org/obo/GO_0036211 protein modification process http://purl.obolibrary.org/obo/GO_0043412 macromolecule modification The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). http://purl.obolibrary.org/obo/GO_0038161 prolactin signaling pathway http://purl.obolibrary.org/obo/GO_0019221 cytokine-mediated signaling pathway The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0040029 epigenetic regulation of gene expression http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression A process that modulates the frequency, rate or extent of gene expression through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or cytosine methylation of DNA. Once established, this regulation may be maintained over many cell divisions. It can also be heritable in the absence of the instigating signal. http://purl.obolibrary.org/obo/GO_0042175 nuclear outer membrane-endoplasmic reticulum membrane network http://purl.obolibrary.org/obo/GO_0016020 membrane The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. http://purl.obolibrary.org/obo/GO_0042180 ketone metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0042181 ketone biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding Binding to a chemokine receptor. http://purl.obolibrary.org/obo/GO_0042416 dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0042427 serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042430 indole-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042446 hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0042447 hormone catabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0042461 photoreceptor cell development http://purl.obolibrary.org/obo/GO_0048666 neuron development Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. http://purl.obolibrary.org/obo/GO_0042562 hormone binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor. http://purl.obolibrary.org/obo/GO_0042886 amide transport http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0042887 amide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0043005 neuron projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. http://purl.obolibrary.org/obo/GO_0043021 ribonucleoprotein complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a complex of RNA and protein. http://purl.obolibrary.org/obo/GO_0043039 tRNA aminoacylation http://purl.obolibrary.org/obo/GO_0043038 amino acid activation The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. http://purl.obolibrary.org/obo/GO_0043066 negative regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043085 positive regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that activates or increases the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0043086 negative regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that stops or reduces the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0043176 amine binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group. http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043255 regulation of carbohydrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. http://purl.obolibrary.org/obo/GO_0043296 apical junction complex http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. http://purl.obolibrary.org/obo/GO_0043412 macromolecule modification http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. http://purl.obolibrary.org/obo/GO_0043455 regulation of secondary metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. http://purl.obolibrary.org/obo/GO_0043470 regulation of carbohydrate catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. http://purl.obolibrary.org/obo/GO_0043648 dicarboxylic acid metabolic process http://purl.obolibrary.org/obo/GO_0019752 carboxylic acid metabolic process The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0043649 dicarboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0043650 dicarboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0044060 regulation of endocrine process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044550 secondary metabolite biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. http://purl.obolibrary.org/obo/GO_0044706 multi-multicellular organism process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organism process which involves another multicellular organism of the same or different species. http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0045214 sarcomere organization http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organization The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0045596 negative regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045814 negative regulation of gene expression, epigenetic http://purl.obolibrary.org/obo/GO_0040029 epigenetic regulation of gene expression An epigenetic process that silences gene expression at specific genomic regions through chromatin remodeling either by modifying higher order chromatin fiber structure, nucleosomal histones, or the cytosine DNA methylation. http://purl.obolibrary.org/obo/GO_0045930 negative regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0046173 polyol biosynthetic process http://purl.obolibrary.org/obo/GO_0046165 alcohol biosynthetic process The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms. http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0046785 microtubule polymerization http://purl.obolibrary.org/obo/GO_0051258 protein polymerization The addition of tubulin heterodimers to one or both ends of a microtubule. http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0046885 regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0046907 intracellular transport http://purl.obolibrary.org/obo/GO_0051641 cellular localization The directed movement of substances within a cell. http://purl.obolibrary.org/obo/GO_0046942 carboxylic acid transport http://purl.obolibrary.org/obo/GO_0015849 organic acid transport The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0046943 carboxylic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carboxylic acids from one side of a membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). http://purl.obolibrary.org/obo/GO_0048029 monosaccharide binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. http://purl.obolibrary.org/obo/GO_0048066 developmental pigmentation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. http://purl.obolibrary.org/obo/GO_0048193 Golgi vesicle transport http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. http://purl.obolibrary.org/obo/GO_0048477 oogenesis http://purl.obolibrary.org/obo/GO_0007292 female gamete generation The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0048523 negative regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0048546 digestive tract morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. http://purl.obolibrary.org/obo/GO_0048565 digestive tract development http://purl.obolibrary.org/obo/GO_0035295 tube development The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed. http://purl.obolibrary.org/obo/GO_0048580 regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. http://purl.obolibrary.org/obo/GO_0048753 pigment granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. http://purl.obolibrary.org/obo/GO_0048806 genitalia development http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048812 neuron projection morphogenesis http://purl.obolibrary.org/obo/GO_0120039 plasma membrane bounded cell projection morphogenesis The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048873 homeostasis of number of cells within a tissue http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue. http://purl.obolibrary.org/obo/GO_0050658 RNA transport http://purl.obolibrary.org/obo/GO_0051236 establishment of RNA localization The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0050768 negative regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a cell adhesion molecule. http://purl.obolibrary.org/obo/GO_0050890 cognition http://purl.obolibrary.org/obo/GO_0050877 nervous system process The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. http://purl.obolibrary.org/obo/GO_0050896 response to stimulus http://purl.obolibrary.org/obo/GO_0008150 biological process Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. http://purl.obolibrary.org/obo/GO_0050953 sensory perception of light stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. http://purl.obolibrary.org/obo/GO_0051031 tRNA transport http://purl.obolibrary.org/obo/GO_0050658 RNA transport The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051053 negative regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051081 nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly The controlled breakdown of the nuclear membranes, for example during cellular division. http://purl.obolibrary.org/obo/GO_0051168 nuclear export http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic transport The directed movement of substances out of the nucleus. http://purl.obolibrary.org/obo/GO_0051169 nuclear transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances into, out of, or within the nucleus. http://purl.obolibrary.org/obo/GO_0051170 import into nucleus http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic transport The directed movement of substances into the nucleus. http://purl.obolibrary.org/obo/GO_0051234 establishment of localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0051261 protein depolymerization http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein. http://purl.obolibrary.org/obo/GO_0051378 serotonin binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0051649 establishment of localization in cell http://purl.obolibrary.org/obo/GO_0051234 establishment of localization Any process, occurring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of a vesicle to a specific location. http://purl.obolibrary.org/obo/GO_0051651 maintenance of location in cell http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051716 cellular response to stimulus http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. http://purl.obolibrary.org/obo/GO_0051783 regulation of nuclear division http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0055086 nucleobase-containing small molecule metabolic process http://purl.obolibrary.org/obo/GO_0044281 small molecule metabolic process The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide. http://purl.obolibrary.org/obo/GO_0060047 heart contraction http://purl.obolibrary.org/obo/GO_0003015 heart process The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body. http://purl.obolibrary.org/obo/GO_0060089 molecular transducer activity http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity A compound molecular function in which an effector function is controlled by one or more regulatory components. http://purl.obolibrary.org/obo/GO_0060281 regulation of oocyte development http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060322 head development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/GO_0060326 cell chemotaxis http://purl.obolibrary.org/obo/GO_0016477 cell migration The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0060404 axonemal microtubule depolymerization http://purl.obolibrary.org/obo/GO_0061523 cilium disassembly The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules. http://purl.obolibrary.org/obo/GO_0060541 respiratory system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_0060612 adipose tissue development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat. http://purl.obolibrary.org/obo/GO_0061024 membrane organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. http://purl.obolibrary.org/obo/GO_0061061 muscle structure development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. http://purl.obolibrary.org/obo/GO_0061462 protein localization to lysosome http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole A process in which a protein is transported to, or maintained in, a location within a lysosome. http://purl.obolibrary.org/obo/GO_0061564 axon development http://purl.obolibrary.org/obo/GO_0031175 neuron projection development The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation). http://purl.obolibrary.org/obo/GO_0065002 intracellular protein transmembrane transport http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen http://purl.obolibrary.org/obo/GO_0043233 organelle lumen An organelle lumen that is part of an intracellular organelle. http://purl.obolibrary.org/obo/GO_0070160 tight junction http://purl.obolibrary.org/obo/GO_0005911 cell-cell junction A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/GO_0070161 anchoring junction http://purl.obolibrary.org/obo/GO_0030054 cell junction A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. http://purl.obolibrary.org/obo/GO_0070192 chromosome organization involved in meiotic cell cycle http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process of chromosome organization that is involved in a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0070231 T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/GO_0070382 exocytic vesicle http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. http://purl.obolibrary.org/obo/GO_0070851 growth factor receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a growth factor receptor. http://purl.obolibrary.org/obo/GO_0071555 cell wall organization http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. http://purl.obolibrary.org/obo/GO_0071705 nitrogen compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0071944 cell periphery http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The broad region around and including the plasma membrane of a cell, encompassing the cell cortex (inside the cell), the plasma membrane, and any external encapsulating structures. http://purl.obolibrary.org/obo/GO_0072089 stem cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0072329 monocarboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. http://purl.obolibrary.org/obo/GO_0072359 circulatory system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0072655 establishment of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_0070585 protein localization to mitochondrion The directed movement of a protein to the mitochondrion or a part of the mitochondrion. http://purl.obolibrary.org/obo/GO_0072666 establishment of protein localization to vacuole http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole The directed movement of a protein to a specific location in a vacuole. http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/GO_0080171 lytic vacuole organization http://purl.obolibrary.org/obo/GO_0007033 vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole. http://purl.obolibrary.org/obo/GO_0090130 tissue migration http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the population of cells that make up a tissue undergo directed movement. http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localization to membrane http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process Any cellular metabolic process involving nucleic acids. http://purl.obolibrary.org/obo/GO_0095500 acetylcholine receptor signaling pathway http://purl.obolibrary.org/obo/GO_0098926 postsynaptic signal transduction The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/GO_0097014 ciliary plasm http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. http://purl.obolibrary.org/obo/GO_0097194 execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0009987 cellular process A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0097435 supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. http://purl.obolibrary.org/obo/GO_0098642 network-forming collagen trimer http://purl.obolibrary.org/obo/GO_0005581 collagen trimer A collagen trimer that forms networks. http://purl.obolibrary.org/obo/GO_0098643 fibrillar collagen http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands). http://purl.obolibrary.org/obo/GO_0098645 collagen network http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers A supramolecular complex that consists of collagen triple helices associated to form a network. http://purl.obolibrary.org/obo/GO_0098664 G protein-coupled serotonin receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands. http://purl.obolibrary.org/obo/GO_0098793 presynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of a synapse that is part of the presynaptic cell. http://purl.obolibrary.org/obo/GO_0098798 mitochondrial protein-containing complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex that is part of a mitochondrion. http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex Any protein complex that is part of the plasma membrane and which functions as a signaling receptor. http://purl.obolibrary.org/obo/GO_0098858 actin-based cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A cell projection supported by an assembly of actin filaments, and which lacks microtubules. http://purl.obolibrary.org/obo/GO_0098862 cluster of actin-based cell projections http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cell part consisting of multiple, closely packed actin-based cell projections. http://purl.obolibrary.org/obo/GO_0098876 vesicle-mediated transport to the plasma membrane http://purl.obolibrary.org/obo/GO_0051668 localization within membrane The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. http://purl.obolibrary.org/obo/GO_0098916 anterograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from pre to post-synapse, across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0098930 axonal transport http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport The directed movement of organelles or molecules along microtubules in axons. http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. http://purl.obolibrary.org/obo/GO_0099500 vesicle fusion to plasma membrane http://purl.obolibrary.org/obo/GO_0140029 exocytic process Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0099531 presynaptic process involved in chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050877 nervous system process The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission. http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. http://purl.obolibrary.org/obo/GO_0099643 signal release from synapse http://purl.obolibrary.org/obo/GO_0023061 signal release Any signal release from a synapse. http://purl.obolibrary.org/obo/GO_1901135 carbohydrate derivative metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901136 carbohydrate derivative catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901137 carbohydrate derivative biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrate derivative. http://purl.obolibrary.org/obo/GO_1901375 acetate ester transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of an acetate ester from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901505 carbohydrate derivative transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carbohydrate derivative from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1901606 alpha-amino acid catabolic process http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901880 negative regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1902653 secondary alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_1902652 secondary alcohol metabolic process The chemical reactions and pathways resulting in the formation of secondary alcohol. http://purl.obolibrary.org/obo/GO_1902850 microtubule cytoskeleton organization involved in mitosis http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process Any microtubule cytoskeleton organization that is involved in mitosis. http://purl.obolibrary.org/obo/GO_1902875 regulation of embryonic pattern specification http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of embryonic pattern specification. http://purl.obolibrary.org/obo/GO_1902903 regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of supramolecular fiber organization. http://purl.obolibrary.org/obo/GO_1902904 negative regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization. http://purl.obolibrary.org/obo/GO_1903429 regulation of cell maturation http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1903664 regulation of asexual reproduction http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of asexual reproduction. http://purl.obolibrary.org/obo/GO_1904115 axon cytoplasm http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm Any cytoplasm that is part of a axon. http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport http://purl.obolibrary.org/obo/GO_0006839 mitochondrial transport The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion. http://purl.obolibrary.org/obo/GO_2000178 negative regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000272 negative regulation of signaling receptor activity http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity. http://purl.obolibrary.org/obo/GO_2000647 negative regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_0045806 negative regulation of endocytosis http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis. http://purl.obolibrary.org/obo/GO_0045807 positive regulation of endocytosis http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of endocytosis. http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0045843 negative regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_0048635 negative regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0045844 positive regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_0048636 positive regulation of muscle organ development Any process that activates or increases the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0045900 negative regulation of translational elongation http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation. http://purl.obolibrary.org/obo/GO_0045901 positive regulation of translational elongation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational elongation. http://purl.obolibrary.org/obo/GO_0045904 negative regulation of translational termination http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0045905 positive regulation of translational termination http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational termination. http://purl.obolibrary.org/obo/GO_0045931 positive regulation of mitotic cell cycle http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that activates or increases the rate or extent of progression through the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_0045932 negative regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0045933 positive regulation of muscle contraction http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of muscle contraction. http://purl.obolibrary.org/obo/GO_0045963 negative regulation of dopamine metabolic process http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine. http://purl.obolibrary.org/obo/GO_0045964 positive regulation of dopamine metabolic process http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine. http://purl.obolibrary.org/obo/GO_0045986 negative regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0045987 positive regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0045992 negative regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0046014 negative regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/GO_0046548 retinal rod cell development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. http://purl.obolibrary.org/obo/GO_0046549 retinal cone cell development http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. http://purl.obolibrary.org/obo/GO_0046666 retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Programmed cell death that occurs in the developing retina. http://purl.obolibrary.org/obo/GO_0046667 compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046666 retinal cell programmed cell death Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium. http://purl.obolibrary.org/obo/GO_0046668 regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0046669 regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046668 regulation of retinal cell programmed cell death Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0046670 positive regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0046671 negative regulation of retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina. http://purl.obolibrary.org/obo/GO_0046672 positive regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046670 positive regulation of retinal cell programmed cell death Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0046673 negative regulation of compound eye retinal cell programmed cell death http://purl.obolibrary.org/obo/GO_0046671 negative regulation of retinal cell programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina. http://purl.obolibrary.org/obo/GO_0046716 muscle cell cellular homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. http://purl.obolibrary.org/obo/GO_0046826 negative regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0046828 regulation of RNA import into nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0046829 negative regulation of RNA import into nucleus http://purl.obolibrary.org/obo/GO_0046823 negative regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0046830 positive regulation of RNA import into nucleus http://purl.obolibrary.org/obo/GO_0046824 positive regulation of nucleocytoplasmic transport Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0046832 negative regulation of RNA export from nucleus http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0046833 positive regulation of RNA export from nucleus http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0047496 vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. http://purl.obolibrary.org/obo/GO_0048048 embryonic eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. http://purl.obolibrary.org/obo/GO_0048070 regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0120305 regulation of pigmentation Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0048086 negative regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0048087 positive regulation of developmental pigmentation http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. http://purl.obolibrary.org/obo/GO_0048132 female germ-line stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098728 germline stem cell asymmetric division The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes. http://purl.obolibrary.org/obo/GO_0048144 fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. http://purl.obolibrary.org/obo/GO_0048145 regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048146 positive regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048147 negative regulation of fibroblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. http://purl.obolibrary.org/obo/GO_0048251 elastic fiber assembly http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. http://purl.obolibrary.org/obo/GO_0048280 vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0007030 Golgi organization The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. http://purl.obolibrary.org/obo/GO_0048288 nuclear membrane fusion involved in karyogamy http://purl.obolibrary.org/obo/GO_0000740 nuclear membrane fusion The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei. http://purl.obolibrary.org/obo/GO_0048313 Golgi inheritance http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance The partitioning of Golgi apparatus between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0048318 axial mesoderm development http://purl.obolibrary.org/obo/GO_0007498 mesoderm development The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. http://purl.obolibrary.org/obo/GO_0048319 axial mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis The process in which the anatomical structures of the axial mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048320 axial mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048339 paraxial mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. http://purl.obolibrary.org/obo/GO_0048340 paraxial mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of the paraxial mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048341 paraxial mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048369 lateral mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structures of the lateral mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048370 lateral mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048389 intermediate mesoderm development http://purl.obolibrary.org/obo/GO_0007498 mesoderm development The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/GO_0048390 intermediate mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis The process in which the anatomical structures of the intermediate mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048391 intermediate mesoderm formation http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0048485 sympathetic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. http://purl.obolibrary.org/obo/GO_0048539 bone marrow development http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048601 oocyte morphogenesis http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte. http://purl.obolibrary.org/obo/GO_0048627 myoblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0048630 skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. http://purl.obolibrary.org/obo/GO_0048631 regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_0048632 negative regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_0048633 positive regulation of skeletal muscle tissue growth http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle growth. http://purl.obolibrary.org/obo/GO_0048644 muscle organ morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0048659 smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0048660 regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0048661 positive regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0048662 negative regulation of smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0048710 regulation of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of astrocyte differentiation. http://purl.obolibrary.org/obo/GO_0048711 positive regulation of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. http://purl.obolibrary.org/obo/GO_0048712 negative regulation of astrocyte differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. http://purl.obolibrary.org/obo/GO_0048713 regulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. http://purl.obolibrary.org/obo/GO_0048714 positive regulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. http://purl.obolibrary.org/obo/GO_0048715 negative regulation of oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation. http://purl.obolibrary.org/obo/GO_0048741 skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0014904 myotube cell development The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048742 regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048743 positive regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048744 negative regulation of skeletal muscle fiber development http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. http://purl.obolibrary.org/obo/GO_0048745 smooth muscle tissue development http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048755 branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). http://purl.obolibrary.org/obo/GO_0048813 dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0048812 neuron projection morphogenesis The process in which the anatomical structures of a dendrite are generated and organized. http://purl.obolibrary.org/obo/GO_0048814 regulation of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of dendrite morphogenesis. http://purl.obolibrary.org/obo/GO_0048847 adenohypophysis formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. http://purl.obolibrary.org/obo/GO_0048848 neurohypophysis morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. http://purl.obolibrary.org/obo/GO_0048849 neurohypophysis formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. http://purl.obolibrary.org/obo/GO_0048850 hypophysis morphogenesis http://purl.obolibrary.org/obo/GO_0022612 gland morphogenesis The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. http://purl.obolibrary.org/obo/GO_0048851 hypophysis formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands. http://purl.obolibrary.org/obo/GO_0048852 diencephalon morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. http://purl.obolibrary.org/obo/GO_0048853 forebrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). http://purl.obolibrary.org/obo/GO_0048854 brain morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). http://purl.obolibrary.org/obo/GO_0048855 adenohypophysis morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. http://purl.obolibrary.org/obo/GO_0048880 sensory system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048934 peripheral nervous system neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0048935 peripheral nervous system neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. http://purl.obolibrary.org/obo/GO_0050657 nucleic acid transport http://purl.obolibrary.org/obo/GO_0015931 nucleobase-containing compound transport The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0050708 regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050709 negative regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0030100 regulation of endocytosis Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material. http://purl.obolibrary.org/obo/GO_0050765 negative regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis. http://purl.obolibrary.org/obo/GO_0050766 positive regulation of phagocytosis http://purl.obolibrary.org/obo/GO_0050764 regulation of phagocytosis Any process that activates or increases the frequency, rate or extent of phagocytosis. http://purl.obolibrary.org/obo/GO_0050773 regulation of dendrite development http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that modulates the frequency, rate or extent of dendrite development. http://purl.obolibrary.org/obo/GO_0050774 negative regulation of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0048814 regulation of dendrite morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis. http://purl.obolibrary.org/obo/GO_0050775 positive regulation of dendrite morphogenesis http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis. http://purl.obolibrary.org/obo/GO_0050803 regulation of synapse structure or activity http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. http://purl.obolibrary.org/obo/GO_0050908 detection of light stimulus involved in visual perception http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050909 sensory perception of taste http://purl.obolibrary.org/obo/GO_0007606 sensory perception of chemical stimulus The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. http://purl.obolibrary.org/obo/GO_0050962 detection of light stimulus involved in sensory perception http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. http://purl.obolibrary.org/obo/GO_0050968 detection of chemical stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0062149 detection of stimulus involved in sensory perception of pain The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050975 sensory perception of touch http://purl.obolibrary.org/obo/GO_0050954 sensory perception of mechanical stimulus The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach). http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information. http://purl.obolibrary.org/obo/GO_0051033 RNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051034 tRNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051033 RNA transmembrane transporter activity Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051059 NF-kappaB binding http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding Binding to NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters. http://purl.obolibrary.org/obo/GO_0051078 meiotic nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process The cell cycle process in which the controlled breakdown of the nuclear membranes during meiotic cell division occurs. http://purl.obolibrary.org/obo/GO_0051080 meiosis II nuclear membrane disassembly http://purl.obolibrary.org/obo/GO_0051078 meiotic nuclear membrane disassembly The controlled breakdown of the nuclear membranes during the second division of meiosis. http://purl.obolibrary.org/obo/GO_0051150 regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051151 negative regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051148 negative regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051152 positive regulation of smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051149 positive regulation of muscle cell differentiation Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051236 establishment of RNA localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of RNA to a specific location. http://purl.obolibrary.org/obo/GO_0051327 meiotic M phase http://purl.obolibrary.org/obo/GO_0000279 M phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051380 norepinephrine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0051457 maintenance of protein location in nucleus http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus. http://purl.obolibrary.org/obo/GO_0051458 corticotropin secretion http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus. http://purl.obolibrary.org/obo/GO_0051459 regulation of corticotropin secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. http://purl.obolibrary.org/obo/GO_0051460 negative regulation of corticotropin secretion http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell. http://purl.obolibrary.org/obo/GO_0051461 positive regulation of corticotropin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell. http://purl.obolibrary.org/obo/GO_0051588 regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051589 negative regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051620 norepinephrine uptake http://purl.obolibrary.org/obo/GO_0015874 norepinephrine transport The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0051621 regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_0051622 negative regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_0051623 positive regulation of norepinephrine uptake http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. http://purl.obolibrary.org/obo/GO_0051630 acetylcholine uptake http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0051631 regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_0051632 negative regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_0051633 positive regulation of acetylcholine uptake http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell. http://purl.obolibrary.org/obo/GO_0051641 cellular localization http://purl.obolibrary.org/obo/GO_0051179 localization A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. http://purl.obolibrary.org/obo/GO_0051645 Golgi localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051646 mitochondrion localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051657 maintenance of organelle location http://purl.obolibrary.org/obo/GO_0051651 maintenance of location in cell Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051659 maintenance of mitochondrion location http://purl.obolibrary.org/obo/GO_0051657 maintenance of organelle location Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051683 establishment of Golgi localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the Golgi to a specific location. http://purl.obolibrary.org/obo/GO_0051684 maintenance of Golgi location http://purl.obolibrary.org/obo/GO_0051657 maintenance of organelle location Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051688 maintenance of plastid location http://purl.obolibrary.org/obo/GO_0051644 plastid localization Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051784 negative regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0051785 positive regulation of nuclear division http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. http://purl.obolibrary.org/obo/GO_0051891 positive regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0051939 gamma-aminobutyric acid import http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. http://purl.obolibrary.org/obo/GO_0051964 negative regulation of synapse assembly http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_0051965 positive regulation of synapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_0051984 positive regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060282 positive regulation of oocyte development http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060283 negative regulation of oocyte development http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0060456 positive regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of a branched epithelium are generated and organized. http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061572 actin filament bundle organization http://purl.obolibrary.org/obo/GO_0007015 actin filament organization A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. http://purl.obolibrary.org/obo/GO_0065007 biological regulation http://purl.obolibrary.org/obo/GO_0008150 biological process Any process that modulates a measurable attribute of any biological process, quality or function. http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0070585 protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the mitochondrion. http://purl.obolibrary.org/obo/GO_0072676 lymphocyte migration http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration The movement of a lymphocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0090278 negative regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0090493 catecholamine uptake http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of catecholamine into a cell. http://purl.obolibrary.org/obo/GO_0090494 dopamine uptake http://purl.obolibrary.org/obo/GO_0015872 dopamine transport The directed movement of dopamine into a cell. http://purl.obolibrary.org/obo/GO_0098728 germline stem cell asymmetric division http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes. http://purl.obolibrary.org/obo/GO_0098762 meiotic cell cycle phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. http://purl.obolibrary.org/obo/GO_0099569 presynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the presynapse. http://purl.obolibrary.org/obo/GO_1900006 positive regulation of dendrite development http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neuron projection development Any process that activates or increases the frequency, rate or extent of dendrite development. http://purl.obolibrary.org/obo/GO_1901694 positive regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901862 negative regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1901863 positive regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that activates or increases the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1901889 negative regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1901890 positive regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1902680 positive regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1902876 negative regulation of embryonic pattern specification http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification. http://purl.obolibrary.org/obo/GO_1902877 positive regulation of embryonic pattern specification http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of embryonic pattern specification. http://purl.obolibrary.org/obo/GO_1903037 regulation of leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1903038 negative regulation of leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022408 negative regulation of cell-cell adhesion Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1903039 positive regulation of leukocyte cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022409 positive regulation of cell-cell adhesion Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. http://purl.obolibrary.org/obo/GO_1903523 negative regulation of blood circulation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1903524 positive regulation of blood circulation http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of blood circulation. http://purl.obolibrary.org/obo/GO_1904397 negative regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904398 positive regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_1904396 regulation of neuromuscular junction development Any process that activates or increases the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904888 cranial skeletal system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. http://purl.obolibrary.org/obo/GO_1904950 negative regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1904951 positive regulation of establishment of protein localization http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of establishment of protein localization. http://purl.obolibrary.org/obo/GO_1905207 regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1905208 negative regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1905209 positive regulation of cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation. http://purl.obolibrary.org/obo/GO_1905517 macrophage migration http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The orderly movement of a macrophage from one site to another. http://purl.obolibrary.org/obo/GO_1905772 positive regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1990009 retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a retinal cell. http://purl.obolibrary.org/obo/GO_2000171 negative regulation of dendrite development http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000737 negative regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000738 positive regulation of stem cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of stem cell differentiation. http://purl.obolibrary.org/obo/GO_2000832 negative regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_2000833 positive regulation of steroid hormone secretion http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of steroid hormone secretion. http://purl.obolibrary.org/obo/GO_1903697 negative regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly. http://purl.obolibrary.org/obo/GO_1903698 positive regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of microvillus assembly. http://purl.obolibrary.org/obo/GO_1903701 substantia propria of cornea development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903702 esophagus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1903789 regulation of amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport Any process that modulates the frequency, rate or extent of amino acid transmembrane transport. http://purl.obolibrary.org/obo/GO_1903804 glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_0015816 glycine transport The directed movement of glycine from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_1903847 regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905651 regulation of artery morphogenesis Any process that modulates the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903848 negative regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905652 negative regulation of artery morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903849 positive regulation of aorta morphogenesis http://purl.obolibrary.org/obo/GO_1905653 positive regulation of artery morphogenesis Any process that activates or increases the frequency, rate or extent of aorta morphogenesis. http://purl.obolibrary.org/obo/GO_1903903 regulation of establishment of T cell polarity http://purl.obolibrary.org/obo/GO_2000114 regulation of establishment of cell polarity Any process that modulates the frequency, rate or extent of establishment of T cell polarity. http://purl.obolibrary.org/obo/GO_1903904 negative regulation of establishment of T cell polarity http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity. http://purl.obolibrary.org/obo/GO_1903905 positive regulation of establishment of T cell polarity http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity. http://purl.obolibrary.org/obo/GO_1903941 negative regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_1903942 positive regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_1903950 negative regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential. http://purl.obolibrary.org/obo/GO_1903951 positive regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential Any process that activates or increases the frequency, rate or extent of AV node cell action potential. http://purl.obolibrary.org/obo/GO_1903978 regulation of microglial cell activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that modulates the frequency, rate or extent of microglial cell activation. http://purl.obolibrary.org/obo/GO_1903979 negative regulation of microglial cell activation http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation. http://purl.obolibrary.org/obo/GO_1903980 positive regulation of microglial cell activation http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response Any process that activates or increases the frequency, rate or extent of microglial cell activation. http://purl.obolibrary.org/obo/GO_1904014 response to serotonin http://purl.obolibrary.org/obo/GO_0071867 response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. http://purl.obolibrary.org/obo/GO_1904015 cellular response to serotonin http://purl.obolibrary.org/obo/GO_0071868 cellular response to monoamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. http://purl.obolibrary.org/obo/GO_1904026 regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1904027 negative regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1904028 positive regulation of collagen fibril organization http://purl.obolibrary.org/obo/GO_1903055 positive regulation of extracellular matrix organization Any process that activates or increases the frequency, rate or extent of collagen fibril organization. http://purl.obolibrary.org/obo/GO_1904057 negative regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1904058 positive regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain Any process that activates or increases the frequency, rate or extent of sensory perception of pain. http://purl.obolibrary.org/obo/GO_1904065 G protein-coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0007213 G protein-coupled acetylcholine receptor signaling pathway Any G protein-coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1904073 regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1904074 negative regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1904075 positive regulation of trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation. http://purl.obolibrary.org/obo/GO_1904092 regulation of autophagic cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the frequency, rate or extent of autophagic cell death. http://purl.obolibrary.org/obo/GO_1904106 protein localization to microvillus http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a microvillus. http://purl.obolibrary.org/obo/GO_1904116 response to vasopressin http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. http://purl.obolibrary.org/obo/GO_1904117 cellular response to vasopressin http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. http://purl.obolibrary.org/obo/GO_1904124 microglial cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of a microglial cell from one site to another. http://purl.obolibrary.org/obo/GO_1904139 regulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration Any process that modulates the frequency, rate or extent of microglial cell migration. http://purl.obolibrary.org/obo/GO_1904140 negative regulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration. http://purl.obolibrary.org/obo/GO_1904141 positive regulation of microglial cell migration http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration Any process that activates or increases the frequency, rate or extent of microglial cell migration. http://purl.obolibrary.org/obo/GO_1904145 negative regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1904146 positive regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1904170 regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904171 negative regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904172 positive regulation of bleb assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of bleb assembly. http://purl.obolibrary.org/obo/GO_1904177 regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1904178 negative regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1904179 positive regulation of adipose tissue development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of adipose tissue development. http://purl.obolibrary.org/obo/GO_1904204 regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1904205 negative regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1904206 positive regulation of skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1904215 regulation of protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma. http://purl.obolibrary.org/obo/GO_1904216 positive regulation of protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma. http://purl.obolibrary.org/obo/GO_1904266 regulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis. http://purl.obolibrary.org/obo/GO_1904267 negative regulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1900148 negative regulation of Schwann cell migration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis. http://purl.obolibrary.org/obo/GO_1904268 positive regulation of Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_1900149 positive regulation of Schwann cell migration Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis. http://purl.obolibrary.org/obo/GO_1904269 cell leading edge cell cortex http://purl.obolibrary.org/obo/GO_0099738 cell cortex region The cell cortex of the leading edge of a cell. http://purl.obolibrary.org/obo/GO_1904338 regulation of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1904339 negative regulation of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1904340 positive regulation of dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1904350 regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0042176 regulation of protein catabolic process Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1904351 negative regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0042177 negative regulation of protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1904352 positive regulation of protein catabolic process in the vacuole http://purl.obolibrary.org/obo/GO_0045732 positive regulation of protein catabolic process Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole. http://purl.obolibrary.org/obo/GO_1904408 melatonin binding http://purl.obolibrary.org/obo/GO_0033218 amide binding Binding to melatonin. http://purl.obolibrary.org/obo/GO_1904409 regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904410 negative regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904411 positive regulation of secretory granule organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of secretory granule organization. http://purl.obolibrary.org/obo/GO_1904412 regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1904413 negative regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1904414 positive regulation of cardiac ventricle development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of cardiac ventricle development. http://purl.obolibrary.org/obo/GO_1904456 negative regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0051970 negative regulation of transmission of nerve impulse Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential. http://purl.obolibrary.org/obo/GO_1904457 positive regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0051971 positive regulation of transmission of nerve impulse Any process that activates or increases the frequency, rate or extent of neuronal action potential. http://purl.obolibrary.org/obo/GO_1904588 cellular response to glycoprotein http://purl.obolibrary.org/obo/GO_1904587 response to glycoprotein Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. http://purl.obolibrary.org/obo/GO_1904606 fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a fat cell. http://purl.obolibrary.org/obo/GO_1904624 regulation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1904625 negative regulation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0060093 negative regulation of synaptic transmission, glycinergic Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1904626 positive regulation of glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0060094 positive regulation of synaptic transmission, glycinergic Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1904649 regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904650 negative regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_1904649 regulation of fat cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904651 positive regulation of fat cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904675 regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division Any process that modulates the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904676 negative regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904677 positive regulation of somatic stem cell division http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division Any process that activates or increases the frequency, rate or extent of somatic stem cell division. http://purl.obolibrary.org/obo/GO_1904693 midbrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process by which a midbrain is generated and organized. http://purl.obolibrary.org/obo/GO_1904697 regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1904698 negative regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1904699 positive regulation of acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the frequency, rate or extent of acinar cell proliferation. http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0048660 regulation of smooth muscle cell proliferation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1904706 negative regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1904707 positive regulation of vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_1904705 regulation of vascular associated smooth muscle cell proliferation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation. http://purl.obolibrary.org/obo/GO_1904738 vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration The orderly movement of a vascular associated smooth muscle cell from one site to another. http://purl.obolibrary.org/obo/GO_1904745 Atg1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form an Atg1/UKL1 kinase complex. http://purl.obolibrary.org/obo/GO_1904749 regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus Any process that modulates the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_1904750 negative regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_1904751 positive regulation of protein localization to nucleolus http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus. http://purl.obolibrary.org/obo/GO_1904752 regulation of vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_1904753 negative regulation of vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014912 negative regulation of smooth muscle cell migration Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_1904754 positive regulation of vascular associated smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014911 positive regulation of smooth muscle cell migration Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_1904770 intramembranous bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The developmental process by which an intramembranous bone is generated and organized. http://purl.obolibrary.org/obo/GO_1904776 regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_1904777 negative regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_1904778 positive regulation of protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. http://purl.obolibrary.org/obo/GO_1904817 serous membrane development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904818 visceral peritoneum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904819 parietal peritoneum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904820 peritoneum development http://purl.obolibrary.org/obo/GO_1904817 serous membrane development The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904821 chloroplast disassembly http://purl.obolibrary.org/obo/GO_0009658 chloroplast organization The disaggregation of a chloroplast into its constituent components. http://purl.obolibrary.org/obo/GO_1904829 regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904830 negative regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905064 negative regulation of vascular associated smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904831 positive regulation of aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905065 positive regulation of vascular associated smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1904933 regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_1904934 negative regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_1904933 regulation of cell proliferation in midbrain Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_1904935 positive regulation of cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain. http://purl.obolibrary.org/obo/GO_1904937 sensory neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of a sensory neuron from one site to another. http://purl.obolibrary.org/obo/GO_1904942 regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation Any process that modulates the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_1904943 negative regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901211 negative regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_1904944 positive regulation of cardiac ventricle formation http://purl.obolibrary.org/obo/GO_1901212 positive regulation of cardiac chamber formation Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation. http://purl.obolibrary.org/obo/GO_1904948 midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0071542 dopaminergic neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron. http://purl.obolibrary.org/obo/GO_1904956 regulation of midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904338 regulation of dopaminergic neuron differentiation Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1904957 negative regulation of midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904956 regulation of midbrain dopaminergic neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1904958 positive regulation of midbrain dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_1904956 regulation of midbrain dopaminergic neuron differentiation Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1904962 plastid to vacuole vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport The vesicle-mediated and directed movement of substances from plastid to vacuole. http://purl.obolibrary.org/obo/GO_1904983 glycine import into mitochondrion http://purl.obolibrary.org/obo/GO_0170036 import into the mitochondrion The process in which glycine is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_1904987 regulation of endothelial cell activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate or extent of endothelial cell activation. http://purl.obolibrary.org/obo/GO_1904988 negative regulation of endothelial cell activation http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation. http://purl.obolibrary.org/obo/GO_1904989 positive regulation of endothelial cell activation http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation Any process that activates or increases the frequency, rate or extent of endothelial cell activation. http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051150 regulation of smooth muscle cell differentiation Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1905064 negative regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1905065 positive regulation of vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_1905063 regulation of vascular associated smooth muscle cell differentiation Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation. http://purl.obolibrary.org/obo/GO_1905071 tight junction disassembly http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly The disaggregation of an tight junction into its constituent components. http://purl.obolibrary.org/obo/GO_1905073 regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of tight junction disassembly. http://purl.obolibrary.org/obo/GO_1905074 negative regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of tight junction disassembly. http://purl.obolibrary.org/obo/GO_1905075 positive regulation of tight junction disassembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of tight junction disassembly. http://purl.obolibrary.org/obo/GO_1905079 regulation of cerebellar neuron development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of cerebellar neuron development. http://purl.obolibrary.org/obo/GO_1905080 negative regulation of cerebellar neuron development http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development. http://purl.obolibrary.org/obo/GO_1905081 positive regulation of cerebellar neuron development http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of cerebellar neuron development. http://purl.obolibrary.org/obo/GO_1905082 regulation of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation Any process that modulates the frequency, rate or extent of mitochondrial translational elongation. http://purl.obolibrary.org/obo/GO_1905083 negative regulation of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_0070130 negative regulation of mitochondrial translation Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation. http://purl.obolibrary.org/obo/GO_1905084 positive regulation of mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_1905082 regulation of mitochondrial translational elongation Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation. http://purl.obolibrary.org/obo/GO_1905126 regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport Any process that modulates the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_1905127 negative regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_1905128 positive regulation of axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport. http://purl.obolibrary.org/obo/GO_1905139 apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_1905140 regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_1905141 negative regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_1905142 positive regulation of apical ectodermal ridge formation http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation. http://purl.obolibrary.org/obo/GO_1905144 response to acetylcholine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. http://purl.obolibrary.org/obo/GO_1905146 lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_0007039 protein catabolic process in the vacuole Any cellular protein catabolic process that takes place in a lysosome. http://purl.obolibrary.org/obo/GO_1905147 regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1905148 negative regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1905149 positive regulation of smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy. http://purl.obolibrary.org/obo/GO_1905165 regulation of lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_1904350 regulation of protein catabolic process in the vacuole Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process. http://purl.obolibrary.org/obo/GO_1905166 negative regulation of lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_1905165 regulation of lysosomal protein catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process. http://purl.obolibrary.org/obo/GO_1905167 positive regulation of lysosomal protein catabolic process http://purl.obolibrary.org/obo/GO_1905165 regulation of lysosomal protein catabolic process Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process. http://purl.obolibrary.org/obo/GO_1905192 regulation of chloroplast fission http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of chloroplast fission. http://purl.obolibrary.org/obo/GO_1905193 negative regulation of chloroplast fission http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission. http://purl.obolibrary.org/obo/GO_1905194 positive regulation of chloroplast fission http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of chloroplast fission. http://purl.obolibrary.org/obo/GO_1905213 negative regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1905223 epicardium morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process by which an epicardium is generated and organized. http://purl.obolibrary.org/obo/GO_1905232 cellular response to L-glutamate http://purl.obolibrary.org/obo/GO_1902065 response to L-glutamate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus. http://purl.obolibrary.org/obo/GO_1905277 negative regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905288 vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell apoptotic process Any apoptotic process in a vascular associated smooth muscle cell. http://purl.obolibrary.org/obo/GO_1905304 regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905305 negative regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905306 positive regulation of cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly. http://purl.obolibrary.org/obo/GO_1905310 regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1905311 negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1905312 positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1905315 cell proliferation involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis Any cell proliferation that is involved in endocardial cushion morphogenesis. http://purl.obolibrary.org/obo/GO_1905319 mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a mesenchymal stem cell from one site to another. http://purl.obolibrary.org/obo/GO_1905320 regulation of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration. http://purl.obolibrary.org/obo/GO_1905321 negative regulation of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration. http://purl.obolibrary.org/obo/GO_1905322 positive regulation of mesenchymal stem cell migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration. http://purl.obolibrary.org/obo/GO_1905384 regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse Any process that modulates the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_1905385 negative regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_1905386 positive regulation of protein localization to presynapse http://purl.obolibrary.org/obo/GO_1902474 positive regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to presynapse. http://purl.obolibrary.org/obo/GO_1905429 response to glycine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. http://purl.obolibrary.org/obo/GO_1905430 cellular response to glycine http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus. http://purl.obolibrary.org/obo/GO_1905432 regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_1905433 negative regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_1905434 positive regulation of retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide. http://purl.obolibrary.org/obo/GO_1905453 regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905454 negative regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905455 positive regulation of myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905456 regulation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905457 negative regulation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905458 positive regulation of lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1905459 regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptotic process Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905460 negative regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034392 negative regulation of smooth muscle cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905461 positive regulation of vascular associated smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0034393 positive regulation of smooth muscle cell apoptotic process Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_1905492 positive regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_1905503 regulation of motile cilium assembly http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly Any process that modulates the frequency, rate or extent of motile cilium assembly. http://purl.obolibrary.org/obo/GO_1905504 negative regulation of motile cilium assembly http://purl.obolibrary.org/obo/GO_1902018 negative regulation of cilium assembly Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly. http://purl.obolibrary.org/obo/GO_1905505 positive regulation of motile cilium assembly http://purl.obolibrary.org/obo/GO_0045724 positive regulation of cilium assembly Any process that activates or increases the frequency, rate or extent of motile cilium assembly. http://purl.obolibrary.org/obo/GO_1905553 regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_1905554 negative regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_1905555 positive regulation of blood vessel branching http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis Any process that activates or increases the frequency, rate or extent of blood vessel branching. http://purl.obolibrary.org/obo/GO_1905557 regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0010549 regulation of membrane disassembly Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_1905558 negative regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_1905559 positive regulation of mitotic nuclear envelope disassembly http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly. http://purl.obolibrary.org/obo/GO_1905562 regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001936 regulation of endothelial cell proliferation Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1905563 negative regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001937 negative regulation of endothelial cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1905564 positive regulation of vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001938 positive regulation of endothelial cell proliferation Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_1905606 regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly Any process that modulates the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_1905607 negative regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_1905606 regulation of presynapse assembly Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_1905608 positive regulation of presynapse assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of presynapse assembly. http://purl.obolibrary.org/obo/GO_1905627 regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_1905628 negative regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_1905629 positive regulation of serotonin biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process. http://purl.obolibrary.org/obo/GO_1905651 regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_1905652 negative regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_1905653 positive regulation of artery morphogenesis http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process Any process that activates or increases the frequency, rate or extent of artery morphogenesis. http://purl.obolibrary.org/obo/GO_1990188 euchromatin binding http://purl.obolibrary.org/obo/GO_0003682 chromatin binding Binding to euchromatin, a dispersed and relatively uncompacted form of chromatin. http://purl.obolibrary.org/obo/GO_1990751 Schwann cell chemotaxis http://purl.obolibrary.org/obo/GO_0036135 Schwann cell migration The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_1990863 acinar cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus). http://purl.obolibrary.org/obo/GO_1990874 vascular associated smooth muscle cell proliferation http://purl.obolibrary.org/obo/GO_0048659 smooth muscle cell proliferation The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. http://purl.obolibrary.org/obo/GO_2000035 regulation of stem cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of stem cell division. http://purl.obolibrary.org/obo/GO_2000172 regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_2001222 regulation of neuron migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of neuron migration. http://purl.obolibrary.org/obo/GO_2001223 negative regulation of neuron migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration. http://purl.obolibrary.org/obo/GO_2001224 positive regulation of neuron migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of neuron migration. http://purl.obolibrary.org/obo/UBERON_0000009 submucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of dense irregular connective tissue that lines organs and supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0000011 parasympathetic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia[GO]. http://purl.obolibrary.org/obo/UBERON_0000012 somatic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Part of peripheral nervous system that includes the somatic parts of the cranial and spinal nerves and their ganglia and the peripheral sensory receptors. http://purl.obolibrary.org/obo/UBERON_0000013 sympathetic nervous system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter [GO]. http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A non-material anatomical entity of two dimensions. Anatomical boundaries are contiguous structures. http://purl.obolibrary.org/obo/UBERON_0000018 compound eye http://purl.obolibrary.org/obo/UBERON_0015165 multi-unit eye A light sensing organ composed of ommatidia. http://purl.obolibrary.org/obo/UBERON_0000019 camera-type eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organ of sight that includes the camera-type eyeball and supporting structures such as the lacrimal apparatus, the conjunctiva, the eyelid. http://purl.obolibrary.org/obo/UBERON_0000025 tube http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Any hollow cylindrical anatomical structure containing a lumen through which substances are transported. http://purl.obolibrary.org/obo/UBERON_0000026 appendage http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Major subdivision of an organism that protrudes from the body[DOS, CARO]. http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A thin layer of loose connective tissue which lies beneath the epithelium and together with the epithelium constitutes the mucosa[WP]. The lamina propria contains capillaries and a central lacteal (lymph vessel) in the small intestine, as well as lymphoid tissue. Lamina propria also contains glands with the ducts opening on to the mucosal epithelium, that secrete mucus and serous secretions. http://purl.obolibrary.org/obo/UBERON_0000031 lamina propria of trachea http://purl.obolibrary.org/obo/UBERON_0004779 respiratory system lamina propria A lamina propria that is part of a respiratory airway. http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that is comprised of a secretory epithelial layer (mesothelium) and a connective tissue layer. http://purl.obolibrary.org/obo/UBERON_0000043 tendon http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue Dense regular connective tissue that connects muscle to bone[VSAO]. http://purl.obolibrary.org/obo/UBERON_0000045 ganglion http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A biological tissue mass, most commonly a mass of nerve cell bodies. http://purl.obolibrary.org/obo/UBERON_0000047 simple eye http://purl.obolibrary.org/obo/UBERON_0000970 eye An eye with one concave chamber. Note that 'simple' does not imply a reduced level of complexity or acuity. http://purl.obolibrary.org/obo/UBERON_0000055 vessel http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular structure that contains, conveys body fluid, such as blood or lymph. http://purl.obolibrary.org/obo/UBERON_0000058 duct http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A tubular structure that transports secreted or excreted substances. http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component adjacent to an organ cavity and which consists of a maximal aggregate of organ component layers. http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that is a single connected structure with inherent 3D shape generated by coordinated expression of the organism's own genome. http://purl.obolibrary.org/obo/UBERON_0000062 organ http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that performs a specific function or group of functions [WP]. http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of an organ that constitutes a distinct modular sub-unit. In some cases, the organ may also contain other sub-units of identical or similar types, in other cases this may be a distinct entity. http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A multicellular structure that is a part of an organ. http://purl.obolibrary.org/obo/UBERON_0000066 fully formed stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The stage of development at which the animal is fully formed, including immaturity and maturity. Includes both sexually immature stage, and adult stage. http://purl.obolibrary.org/obo/UBERON_0000068 embryo stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A life cycle stage that starts with fertilization and ends with the fully formed embryo. http://purl.obolibrary.org/obo/UBERON_0000071 death stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage End of the life of an organism. http://purl.obolibrary.org/obo/UBERON_0000072 proximo-distal subdivision of respiratory tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube An section of a respiratory tract. http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure Any part or collection of parts of the central or peripheral nervous system. Parts may span both CNS and PNS. http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements and articular elements that are part of an individual subdivision of the organism. http://purl.obolibrary.org/obo/UBERON_0000076 external ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The surface (external) layer of ectoderm which begins to proliferate shortly after separation from the neuroectoderm. http://purl.obolibrary.org/obo/UBERON_0000077 mixed endoderm/mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure An anatomical structure that develops from the endoderm and the mesoderm. http://purl.obolibrary.org/obo/UBERON_0000078 mixed ectoderm/mesoderm/endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure An anatomical structure that develops from the ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/UBERON_0000085 morula http://purl.obolibrary.org/obo/UBERON_0000922 embryo A spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/UBERON_0000086 zona pellucida http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane A glycoprotein membrane surrounding the plasma membrane of an oocyte. It is a vital constitutive part of the latter, external but not extraneous to it. The zona pellucida first appears in multilaminar primary oocytes. http://purl.obolibrary.org/obo/UBERON_0000087 inner cell mass http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A mass of cells that develop into the body of the embryo and some extraembryonic tissues. http://purl.obolibrary.org/obo/UBERON_0000088 trophoblast http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mesectodermal cell layer arising from the trophectoderm that erodes the uterine mucosa and contributes to the formation of the placenta. http://purl.obolibrary.org/obo/UBERON_0000091 bilaminar disc http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A flattened, almost circular bilaminar plate of cells formed when the inner cell mass (aka embryoblast) forms two epithelial layers, each of a distinct lineage, separated by an extracellular basement membrane: the external (dorsal) layer is called the epiblast and the internal (ventral) layer is called the hypoblast (aka primitive endoderm); together, they compose the bilaminar embryonic disc. http://purl.obolibrary.org/obo/UBERON_0000092 post-embryonic stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage Stage succeeding embryo, including mature structure. http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Nonparenchymatous organ that primarily consists of dense connective tissue organized into a sheet which interconnects two or more organs, separates two or more body spaces from one another, or surrounds an organ or body part. Examples: interosseous membrane of forearm, obturator membrane, tympanic membrane, fibrous pericardium, fascia lata, dura mater. [FMA]. http://purl.obolibrary.org/obo/UBERON_0000095 cardiac neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of neural crest that develops from the dorsal neural tube. It overlaps the vagal neural crest and migrates to populate the pharyngeal arches 3, 4 and 6 (producing structures in the head) and to the heart, forming connective tissue that separates the great vessels of the heart. [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0000102 lung vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs[GO]. http://purl.obolibrary.org/obo/UBERON_0000104 life cycle http://purl.obolibrary.org/obo/UBERON_0000000 processual entity An entire span of an organism's life. In metazoans, commences with the zygote stage and ends with the death of the organism. http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage http://purl.obolibrary.org/obo/UBERON_0000000 processual entity A spatiotemporal region encompassing some part of the life cycle of an organism. http://purl.obolibrary.org/obo/UBERON_0000106 zygote stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage at which the organism is a single cell produced by means of sexual reproduction. http://purl.obolibrary.org/obo/UBERON_0000107 cleavage stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage The first few specialized divisions of an activated animal egg; Stage consisting of division of cells in the early embryo. The zygotes of many species undergo rapid cell cycles with no significant growth, producing a cluster of cells the same size as the original zygote. The different cells derived from cleavage are called blastomeres and form a compact mass called the morula. Cleavage ends with the formation of the blastula. http://purl.obolibrary.org/obo/UBERON_0000108 blastula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage An early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000109 gastrula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage defined by complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/UBERON_0000110 neurula stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A chordate developmental stage defined by the formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/UBERON_0000111 organogenesis stage http://purl.obolibrary.org/obo/UBERON_0000105 life cycle stage A stage at which the ectoderm, endoderm, and mesoderm develop into the internal organs of the organism. http://purl.obolibrary.org/obo/UBERON_0000114 lung connective tissue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The connective tissue located between the respiratory (airway and alveolar) epithelium, the capillary endothelium and pleural mesothelium; it contains basement membrane composed of collagen, elastin, proteoglycans, and fibronectin. http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium The epithelial layer of the lung. http://purl.obolibrary.org/obo/UBERON_0000117 respiratory tube http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube in the respiratory system. Examples: bronchus, bronchiole, trachea. http://purl.obolibrary.org/obo/UBERON_0000118 lung bud http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud Structure derived from foregut that becomes a lung[GO]. http://purl.obolibrary.org/obo/UBERON_0000119 cell layer http://purl.obolibrary.org/obo/UBERON_0000957 lamina Portion of tissue, that consists of single layer of cells connected to each other by cell junctions. Examples: layer of glial cells; epithelium. http://purl.obolibrary.org/obo/UBERON_0000120 blood brain barrier http://purl.obolibrary.org/obo/UBERON_0000119 cell layer Cell layer consisting of lining cells that separates the central nervous system and the bloodstream. The BBB may consist of endothelial cells or glial cells. An endothelial barrier may have arisen independently several times during evolution. In bichir and lungfish the barrier is formed by brain endothelial cells, while in sturgeon it is formed by a complex perivascular glial sheath, but with no detectable tight junctions. http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A fasciculated bundle of neuron projections (GO:0043005), largely or completely lacking synapses. http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A spatially aggregated collection of nerve cell bodies in the CNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections, and including nearby cells that share the same cell type, chemical phenotype, and connections. (CUMBO). http://purl.obolibrary.org/obo/UBERON_0000126 cranial nerve nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus that receives projections from or contains neurons that send projections through one of the cranial nerves. http://purl.obolibrary.org/obo/UBERON_0000161 orifice http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Anatomical conduit that connects two adjacent body spaces (or a body space with the space surrounding the organism)[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0000166 oral opening http://purl.obolibrary.org/obo/UBERON_0000161 orifice The orifice that connects the mouth to the exterior of the body. http://purl.obolibrary.org/obo/UBERON_0000170 pair of lungs http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection The pair of anatomical structures comprised of a left lung and right lung. http://purl.obolibrary.org/obo/UBERON_0000171 respiration organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ that functions in gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Circulating fluid that is part of the hemolymphoid system. Blood, lymph, interstitial fluid or its analogs. http://purl.obolibrary.org/obo/UBERON_0000201 endothelial blood brain barrier http://purl.obolibrary.org/obo/UBERON_0000120 blood brain barrier A blood brain barrier that is composed of endothelial cells. http://purl.obolibrary.org/obo/UBERON_0000202 glial blood brain barrier http://purl.obolibrary.org/obo/UBERON_0000120 blood brain barrier A blood brain barrier composed of glial cells. http://purl.obolibrary.org/obo/UBERON_0000203 pallium http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Dorsal part (roof region) of the telencephalon[GO]. http://purl.obolibrary.org/obo/UBERON_0000204 ventral part of telencephalon http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Ventral part (base region) of the telencephalon. http://purl.obolibrary.org/obo/UBERON_0000307 blastula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the blastula stage - an early stage of embryonic development in animals. It is produced by cleavage of a fertilized ovum and consists of a spherical layer of around 128 cells surrounding a central fluid-filled cavity called the blastocoel. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/UBERON_0000328 gut wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The wall of the digestive tract. This encompasses all parts of the digestive tract with the exception of the lumen (cavity). http://purl.obolibrary.org/obo/UBERON_0000332 yellow bone marrow http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow Bone marrow in which the fat cells predominate in the meshes of the reticular network. http://purl.obolibrary.org/obo/UBERON_0000344 mucosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A lining of mostly endodermal origin, covered in epithelium, which is involved in absorption and secretion. They line various body cavities that are exposed to the external environment and internal organs. It is at several places continuous with skin: at the nostrils, the lips, the ears, the genital area, and the anus. The sticky, thick fluid secreted by the mucous membranes and gland is termed mucus. The term mucous membrane refers to where they are found in the body and not every mucous membrane secretes mucus[WP]. http://purl.obolibrary.org/obo/UBERON_0000349 limbic system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A set of midline structures surrounding the brainstem of the mammalian brain, originally described anatomically, e.g., hippocampal formation, amygdala, hypothalamus, cingulate cortex. Although the original designation was anatomical, the limbic system has come to be associated with the system in the brain subserving emotional functions. As such, it is very poorly defined and doesn't correspond closely to the anatomical meaning any longer. [BirnLex]. http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma http://purl.obolibrary.org/obo/UBERON_0000064 organ part Functional part of an organ in the body. This is in contrast to the stroma, which refers to the structural tissue of organs, being exactly, connective tissues. http://purl.obolibrary.org/obo/UBERON_0000355 pharyngeal mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000358 blastocyst http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm[GO]. http://purl.obolibrary.org/obo/UBERON_0000361 red bone marrow http://purl.obolibrary.org/obo/UBERON_0002371 bone marrow The red vascular substance consisting of connective tissue and blood vessels, containing primitive blood cells, macrophages, megakaryocytes, and fat cells. Red marrow is found in the cavities of many bones. It manufactures and releases leukocytes and erythrocytes into the bloodstream. http://purl.obolibrary.org/obo/UBERON_0000369 corpus striatum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The corpus striatum (striated body) is a compound structure consisting of the caudate nucleus and the lentiform nucleus, which consists of the putamen and the globus pallidus[WP]. http://purl.obolibrary.org/obo/UBERON_0000371 syncytiotrophoblast http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Extraembryonic cells of trophoblastic shell surrounding embryo, outside the cytotrophoblast layer, involved with implantation of the blastocyst by eroding extracellular matrix surrounding maternal endometrial cells at site of implantation, also contribute to villi. (dark staining, multinucleated). http://purl.obolibrary.org/obo/UBERON_0000375 mandibular nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The motor and sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the auricle, the external acoustic meatus, tympanic membrane, temporal region, the cheek, the skin overlying the mandible, the anterior portion of the tongue, the floor of the mouth, lower teeth and gingiva and transmits motor information from the muscles of mastication, the mylohyoid muscle and digastric muscle and the muscles tensor tympani and tensor veli palatini. http://purl.obolibrary.org/obo/UBERON_0000377 maxillary nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The sensory nerve subdivision of the trigeminal nerve that transmits sensory information from the palate, upper teeth and gingiva, the skin between the palpebral fissure and the mouth, and from the nasal cavity and maxillary sinuses. http://purl.obolibrary.org/obo/UBERON_0000378 tongue muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate The muscular portion of the tongue. http://purl.obolibrary.org/obo/UBERON_0000379 tracheal mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0000383 musculature of body http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The subdivision of the musculoskeletal system that consists of all the muscles of the body[VSAO, modified]. http://purl.obolibrary.org/obo/UBERON_0000389 lens cortex http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Tissue that surrounds the lens nucleus. http://purl.obolibrary.org/obo/UBERON_0000390 lens nucleus http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ The core of the crystalline lens, surrounded by the cortex. http://purl.obolibrary.org/obo/UBERON_0000409 serous gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland A gland in which the principal secretory cells are serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0000410 bronchial mucosa http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa A mucosa that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel An anatomical wall that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0000437 arachnoid barrier layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The arachnoid barrier layer is a part of the arachnoid meningeal layer. It is formed by tight junctions between the endothelial cells of cerebral capillaries in the arachnoid mater. http://purl.obolibrary.org/obo/UBERON_0000446 septum of telencephalon http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter Gray matter structure located on the midline of the forebrain consisting of the septum pellucidum (in some species) and the septal nuclei (Heimer, 1996). http://purl.obolibrary.org/obo/UBERON_0000454 cerebral subcortex http://purl.obolibrary.org/obo/UBERON_0000064 organ part The layer located below the cerebral cortex that includes the forebrain, midbrain and hindbrain. http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is produced by exocrine glands. http://purl.obolibrary.org/obo/UBERON_0000457 cavernous artery http://purl.obolibrary.org/obo/UBERON_0001637 artery Any of several small branches of the internal carotid artery that supply the trigeminal ganglion and the walls of the cavernous and petrosal sinuses. http://purl.obolibrary.org/obo/UBERON_0000463 organism substance http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity in a gaseous, liquid, semisolid or solid state; produced by anatomical structures or derived from inhaled and ingested substances that have been modified by anatomical structures as they pass through the body. http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity Non-material anatomical entity of three dimensions, that is generated by morphogenetic or other physiologic processes; is surrounded by one or more anatomical structures; contains one or more organism substances or anatomical structures. http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has mass. http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity Anatomical entity that has no mass. http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that is an individual member of a species and consists of more than one cell. http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure which is a subdivision of a whole organism, consisting of components of multiple anatomical systems, largely surrounded by a contiguous region of integument. http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that consists of cell parts and cell substances and together does not constitute a cell or a tissue. http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group Anatomical group whose component anatomical structures lie in close proximity to each other. http://purl.obolibrary.org/obo/UBERON_0000478 extraembryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A multicellular anatomical structure that is associated with an embryo and derived from the zygote from which it develops, but which does not contribute to the embryo proper or to structures that are part of the same organism after embryogenesis. http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Multicellular anatomical structure that consists of many cells of one or a few types, arranged in an extracellular matrix such that their long-range organisation is at least partly a repetition of their short-range organisation. http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Anatomical structure that has as its parts two or more portions of tissue of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona-fide boundaries from other distinct structural units of different types. http://purl.obolibrary.org/obo/UBERON_0000482 basal lamina of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane Acellular anatomical structure that consists of a thin sheet of fibrous proteins that underlie and support the cells of an epithelium. It separates the cells of an epithelium from any underlying tissue. http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue, that consists of one or more layers of epithelial cells connected to each other by cell junctions and which is underlain by a basal lamina. Examples: simple squamous epithelium, glandular cuboidal epithelium, transitional epithelium, myoepithelium[CARO]. http://purl.obolibrary.org/obo/UBERON_0000484 simple cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0010077 cuboidal epithelium Unilaminar epithelium that consists of a single layer of cuboidal cells. http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium Unilaminar epithelium, which consists of a single layer of columnar cells. Examples: ciliated columnar epithelium, gastric epithelium, microvillus columnar epithelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000486 multilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of more than one layer of epithelial cells that may or may not be in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, ciliated stratified columnar epithelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000487 simple squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium Unilaminar epithelium which consists of a single layer of squamous cells. Examples: pulmonary alveolar epithelium, endothelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000488 atypical epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium that consists of epithelial cells not arranged in one ore more layers. http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ Compound organ that contains one or more macroscopic anatomical spaces. http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium which consists of a single layer of epithelial cells. Examples: endothelium, mesothelium, glandular squamous epithelium.[FMA]. http://purl.obolibrary.org/obo/UBERON_0000916 abdomen http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The subdivision of the vertebrate body between the thorax and pelvis. The ventral part of the abdomen contains the abdominal cavity and visceral organs. The dorsal part includes the abdominal section of the vertebral column. http://purl.obolibrary.org/obo/UBERON_0000922 embryo http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Anatomical entity that comprises the organism in the early stages of growth and differentiation that are characterized by cleavage, the laying down of fundamental tissues, and the formation of primitive organs and organ systems. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/UBERON_0000923 germ layer http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A layer of cells produced during the process of gastrulation during the early development of the animal embryo, which is distinct from other such layers of cells, as an early step of cell differentiation. The three types of germ layers are the endoderm, ectoderm, and mesoderm. http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that is the outer of the embryo's three germ layers and gives rise to epidermis and neural tissue. http://purl.obolibrary.org/obo/UBERON_0000925 endoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer Primary germ layer that lies remote from the surface of the embryo and gives rise to internal tissues such as gut. http://purl.obolibrary.org/obo/UBERON_0000926 mesoderm http://purl.obolibrary.org/obo/UBERON_0000923 germ layer The middle germ layer of the embryo, between the endoderm and ectoderm. http://purl.obolibrary.org/obo/UBERON_0000930 stomodeum http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Anterior part of the embryonic digestive tract that develops into a mouth. The stomodeum includes as parts an invagination of the ectoderm and the stomodeal cavity. http://purl.obolibrary.org/obo/UBERON_0000956 cerebral cortex http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer The thin layer of gray matter on the surface of the cerebral hemisphere that develops from the telencephalon. It consists of the neocortex (6 layered cortex or isocortex), the hippocampal formation and the olfactory cortex. http://purl.obolibrary.org/obo/UBERON_0000957 lamina http://purl.obolibrary.org/obo/UBERON_0000479 tissue Any thin layer or plate. http://purl.obolibrary.org/obo/UBERON_0000962 nerve of cervical vertebra http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The cervical nerves are the spinal nerves from the cervical vertebrae. Although there are seven cervical vertebrae (C1-C7), there are eight cervical nerves (C1-C8). All nerves except C8 emerge above their corresponding vertebrae, while the C8 nerve emerges below the C7 vertebra. (In the other portions of the spine, the nerve emerges below the vertebra with the same name. Dorsal (posterior) distribution includes the greater occipital (C2) and third occipital (C3). Ventral (anterior) distribution includes the cervical plexus (C1-C4) and brachial plexus (C5-C8) [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0000971 ommatidium http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum The smallest morphological and functional unit of the compound eye that consists of a usually limited and often constant number of rhabdomeric photoreceptor cells, cornea-secreting epithelial cells, and interommatidial pigment cells, and may additionally contain crystalline cone cells. http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint http://purl.obolibrary.org/obo/UBERON_0004905 articulation Anatomical structure that consists of two or more adjacent skeletal structures, which may be interconnected by various types of tissue[VSAO]. http://purl.obolibrary.org/obo/UBERON_0000988 pons http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The part of the central nervous system lying between the medulla oblongata and the midbrain, ventral to the cerebellum. http://purl.obolibrary.org/obo/UBERON_0001005 respiratory airway http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit An airway through which respiratory air passes in organisms. http://purl.obolibrary.org/obo/UBERON_0001009 circulatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis[WP]. http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Portion of connective tissue composed of adipocytes enmeshed in areolar tissue. http://purl.obolibrary.org/obo/UBERON_0001015 musculature http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision A subdivision of the muscular system corresponding to a subdisivision of an organism. http://purl.obolibrary.org/obo/UBERON_0001019 nerve fasciculus http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A slender neuron projection bundle[FBbt]; A bundle of anatomical fibers, as of muscle or nerve (American Heritage Dictionary 4th ed). http://purl.obolibrary.org/obo/UBERON_0001021 nerve http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle An enclosed, cable-like bundle of axons in the peripheral nervous system originating in a nerve root in the central nervous system (or a condensed nervous structure) connecting with peripheral structures. http://purl.obolibrary.org/obo/UBERON_0001027 sensory nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that transmits from sensory receptors on the surface of the body to the central nervous system. http://purl.obolibrary.org/obo/CHEBI_28084 3-(carbamoyloxymethyl)cephalosporin http://purl.obolibrary.org/obo/CHEBI_23066 cephalosporin http://purl.obolibrary.org/obo/CHEBI_23765 quinolone http://purl.obolibrary.org/obo/CHEBI_26513 quinolines http://purl.obolibrary.org/obo/CHEBI_38295 azabicycloalkane http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_46733 oxabicycloalkane http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_22728 benzopyrrole http://purl.obolibrary.org/obo/CHEBI_38180 polycyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_38311 cephem http://purl.obolibrary.org/obo/CHEBI_38106 organosulfur heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_38298 benzodioxoles http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_35570 mancude organic heterobicyclic parent http://purl.obolibrary.org/obo/CHEBI_35571 mancude organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_7528 netilmycin http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic http://purl.obolibrary.org/obo/CHEBI_23853 dithiol http://purl.obolibrary.org/obo/CHEBI_29256 thiol http://purl.obolibrary.org/obo/CHEBI_38106 organosulfur heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_24532 organic heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35341 steroid http://purl.obolibrary.org/obo/CHEBI_26761 steroid antibiotic http://purl.obolibrary.org/obo/CHEBI_49319 carbocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_47880 steroid ester http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_8269 Pleuromutilin http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone http://purl.obolibrary.org/obo/CHEBI_25558 organonitrogen heterocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_24531 heterocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_38329 oxazolidines http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_38304 diazolidine http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_46952 oxazinane http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_48908 triazolobenzothiazole http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound http://purl.obolibrary.org/obo/CHEBI_26144 piperazines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_26151 piperidines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_50893 azaarene http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_46770 pyrrolidinecarboxamide http://purl.obolibrary.org/obo/CHEBI_29347 monocarboxylic acid amide http://purl.obolibrary.org/obo/CHEBI_23232 chromenes http://purl.obolibrary.org/obo/CHEBI_38443 1-benzopyran http://purl.obolibrary.org/obo/CHEBI_26580 rifamycins http://purl.obolibrary.org/obo/CHEBI_22565 ansamycin http://purl.obolibrary.org/obo/CHEBI_33670 heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_33661 monocyclic compound http://purl.obolibrary.org/obo/CHEBI_49103 drug metabolite http://purl.obolibrary.org/obo/CHEBI_76967 human xenobiotic metabolite http://purl.obolibrary.org/obo/CHEBI_30803 isophthalate(2-) http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion http://purl.obolibrary.org/obo/CHEBI_19834 3',5'-cyclic purine nucleotide http://purl.obolibrary.org/obo/CHEBI_36982 cyclic purine nucleotide http://purl.obolibrary.org/obo/CHEBI_48975 substituted aniline http://purl.obolibrary.org/obo/CHEBI_22562 anilines http://purl.obolibrary.org/obo/CHEBI_33408 pnictogen oxoacid http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33484 chalcogen oxoacid http://purl.obolibrary.org/obo/CHEBI_24833 oxoacid http://purl.obolibrary.org/obo/CHEBI_39208 antibiotic insecticide http://purl.obolibrary.org/obo/CHEBI_39215 antibiotic pesticide http://purl.obolibrary.org/obo/CHEBI_35117 manganese coordination entity http://purl.obolibrary.org/obo/CHEBI_33861 transition element coordination entity http://purl.obolibrary.org/obo/CHEBI_39217 antibiotic nematicide http://purl.obolibrary.org/obo/CHEBI_39215 antibiotic pesticide http://purl.obolibrary.org/obo/CHEBI_50335 organic nitrogen anion http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_35693 dicarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_52440 cephalosporin carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_29067 carboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_50320 nucleoside residue http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_51447 organic univalent group http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_51446 organic divalent group http://purl.obolibrary.org/obo/CHEBI_33247 organic group http://purl.obolibrary.org/obo/CHEBI_33666 polycyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_24278 glucoside http://purl.obolibrary.org/obo/CHEBI_35313 hexoside http://purl.obolibrary.org/obo/CHEBI_26561 ribonucleotide http://purl.obolibrary.org/obo/CHEBI_26562 ribose phosphate http://purl.obolibrary.org/obo/CHEBI_23447 cyclic nucleotide http://purl.obolibrary.org/obo/CHEBI_36976 nucleotide http://purl.obolibrary.org/obo/CHEBI_27171 organic heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33672 heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_22727 benzopyran http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_38163 organic heterotetracyclic compound http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_22506 aminoglycan http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound http://purl.obolibrary.org/obo/CHEBI_16976 hygromycin B http://purl.obolibrary.org/obo/CHEBI_24753 hygromycin http://purl.obolibrary.org/obo/CHEBI_26216 potassium atom http://purl.obolibrary.org/obo/CHEBI_22314 alkali metal atom http://purl.obolibrary.org/obo/CHEBI_26708 sodium atom http://purl.obolibrary.org/obo/CHEBI_22314 alkali metal atom http://purl.obolibrary.org/obo/CHEBI_23870 dodecyl group http://purl.obolibrary.org/obo/CHEBI_22323 alkyl group http://purl.obolibrary.org/obo/CHEBI_23905 monoatomic anion http://purl.obolibrary.org/obo/CHEBI_24867 monoatomic ion http://purl.obolibrary.org/obo/CHEBI_24834 inorganic anion http://purl.obolibrary.org/obo/CHEBI_36914 inorganic ion http://purl.obolibrary.org/obo/CHEBI_36830 monoanion http://purl.obolibrary.org/obo/CHEBI_22563 anion http://purl.obolibrary.org/obo/CHEBI_28079 beta-L-arabinoside http://purl.obolibrary.org/obo/CHEBI_22601 arabinoside http://purl.obolibrary.org/obo/CHEBI_22702 benzamides http://purl.obolibrary.org/obo/CHEBI_22645 arenecarboxamide http://purl.obolibrary.org/obo/CHEBI_38443 1-benzopyran http://purl.obolibrary.org/obo/CHEBI_22727 benzopyran http://purl.obolibrary.org/obo/CHEBI_24897 isoindoles http://purl.obolibrary.org/obo/CHEBI_22728 benzopyrrole http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic http://purl.obolibrary.org/obo/CHEBI_47779 aminoglycoside http://purl.obolibrary.org/obo/CHEBI_33429 monoatomic monoanion http://purl.obolibrary.org/obo/CHEBI_36830 monoanion http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation http://purl.obolibrary.org/obo/CHEBI_25414 monoatomic monocation http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_30412 monoatomic dication http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_21638 N-acylglucosamine http://purl.obolibrary.org/obo/CHEBI_21656 N-acyl-hexosamine http://purl.obolibrary.org/obo/CHEBI_33280 molecular messenger http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_52208 biophysical role http://purl.obolibrary.org/obo/CHEBI_24432 biological role http://purl.obolibrary.org/obo/CHEBI_24062 fluorine molecular entity http://purl.obolibrary.org/obo/CHEBI_24471 halogen molecular entity http://purl.obolibrary.org/obo/CHEBI_24860 iodine molecular entity http://purl.obolibrary.org/obo/CHEBI_24471 halogen molecular entity http://purl.obolibrary.org/obo/CHEBI_23116 chlorine atom http://purl.obolibrary.org/obo/CHEBI_24473 halogen http://purl.obolibrary.org/obo/CHEBI_24061 fluorine atom http://purl.obolibrary.org/obo/CHEBI_24473 halogen http://purl.obolibrary.org/obo/CHEBI_25807 organooxygen heterocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_24531 heterocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_24531 heterocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_24532 organic heterocyclic compound http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_33670 heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_21656 N-acyl-hexosamine http://purl.obolibrary.org/obo/CHEBI_24586 hexosamine http://purl.obolibrary.org/obo/CHEBI_38119 brassinin http://purl.obolibrary.org/obo/CHEBI_38129 dithiocarbamic ester http://purl.obolibrary.org/obo/CHEBI_33461 phosphorus oxoanion http://purl.obolibrary.org/obo/CHEBI_33459 pnictogen oxoanion http://purl.obolibrary.org/obo/CHEBI_24839 inorganic salt http://purl.obolibrary.org/obo/CHEBI_24866 salt http://purl.obolibrary.org/obo/CHEBI_36914 inorganic ion http://purl.obolibrary.org/obo/CHEBI_24870 ion http://purl.obolibrary.org/obo/CHEBI_49637 hydrogen atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_24836 inorganic oxide http://purl.obolibrary.org/obo/CHEBI_25741 oxide http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_33465 elemental pnictogen http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_38702 inorganic sodium salt http://purl.obolibrary.org/obo/CHEBI_26714 sodium salt http://purl.obolibrary.org/obo/CHEBI_24840 inorganic sulfate salt http://purl.obolibrary.org/obo/CHEBI_35175 sulfate salt http://purl.obolibrary.org/obo/CHEBI_36093 inorganic chloride http://purl.obolibrary.org/obo/CHEBI_23114 chloride salt http://purl.obolibrary.org/obo/CHEBI_33958 halide salt http://purl.obolibrary.org/obo/CHEBI_37578 halide http://purl.obolibrary.org/obo/CHEBI_35175 sulfate salt http://purl.obolibrary.org/obo/CHEBI_26820 sulfates http://purl.obolibrary.org/obo/CHEBI_24868 organic salt http://purl.obolibrary.org/obo/CHEBI_24866 salt http://purl.obolibrary.org/obo/CHEBI_35479 alkali metal salt http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_23906 monoatomic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_22986 calcium ionophore http://purl.obolibrary.org/obo/CHEBI_24869 ionophore http://purl.obolibrary.org/obo/CHEBI_24867 monoatomic ion http://purl.obolibrary.org/obo/CHEBI_33238 monoatomic entity http://purl.obolibrary.org/obo/CHEBI_25699 organic ion http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_33515 transition element cation http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_33504 alkali metal cation http://purl.obolibrary.org/obo/CHEBI_25213 metal cation http://purl.obolibrary.org/obo/CHEBI_25471 naphthalenemonosulfonate http://purl.obolibrary.org/obo/CHEBI_25478 naphthalenesulfonate http://purl.obolibrary.org/obo/CHEBI_24473 halogen http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_25555 nitrogen atom http://purl.obolibrary.org/obo/CHEBI_33300 pnictogen http://purl.obolibrary.org/obo/CHEBI_25805 oxygen atom http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen http://purl.obolibrary.org/obo/CHEBI_27594 carbon atom http://purl.obolibrary.org/obo/CHEBI_33306 carbon group element atom http://purl.obolibrary.org/obo/CHEBI_28659 phosphorus atom http://purl.obolibrary.org/obo/CHEBI_33300 pnictogen http://purl.obolibrary.org/obo/CHEBI_39430 dioxolane http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_35555 mancude organic heteromonocyclic parent http://purl.obolibrary.org/obo/CHEBI_35571 mancude organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_38099 thiadiazoles http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_36389 saturated organic heteromonocyclic parent http://purl.obolibrary.org/obo/CHEBI_36388 saturated organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_25703 organic phosphate http://purl.obolibrary.org/obo/CHEBI_26020 phosphate http://purl.obolibrary.org/obo/CHEBI_26562 ribose phosphate http://purl.obolibrary.org/obo/CHEBI_25900 aldopentose phosphate http://purl.obolibrary.org/obo/CHEBI_39215 antibiotic pesticide http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_36360 phosphorus oxoacids and derivatives http://purl.obolibrary.org/obo/CHEBI_26082 phosphorus molecular entity http://purl.obolibrary.org/obo/CHEBI_37247 elemental potassium http://purl.obolibrary.org/obo/CHEBI_26217 potassium molecular entity http://purl.obolibrary.org/obo/CHEBI_36982 cyclic purine nucleotide http://purl.obolibrary.org/obo/CHEBI_23447 cyclic nucleotide http://purl.obolibrary.org/obo/CHEBI_35285 iminium betaine http://purl.obolibrary.org/obo/CHEBI_35281 onium betaine http://purl.obolibrary.org/obo/CHEBI_37246 elemental sodium http://purl.obolibrary.org/obo/CHEBI_26712 sodium molecular entity http://purl.obolibrary.org/obo/CHEBI_38700 organic sodium salt http://purl.obolibrary.org/obo/CHEBI_24868 organic salt http://purl.obolibrary.org/obo/CHEBI_29688 telithromycin http://purl.obolibrary.org/obo/CHEBI_28963 amino sugar http://purl.obolibrary.org/obo/CHEBI_23443 cyclic amide http://purl.obolibrary.org/obo/CHEBI_32988 amide http://purl.obolibrary.org/obo/CHEBI_46844 N-acylpiperazine http://purl.obolibrary.org/obo/CHEBI_26144 piperazines http://purl.obolibrary.org/obo/CHEBI_37958 dye http://purl.obolibrary.org/obo/CHEBI_33232 application http://purl.obolibrary.org/obo/CHEBI_50533 protein denaturant http://purl.obolibrary.org/obo/CHEBI_33232 application http://purl.obolibrary.org/obo/CHEBI_33433 monoatomic halogen http://purl.obolibrary.org/obo/CHEBI_33238 monoatomic entity http://purl.obolibrary.org/obo/CHEBI_33861 transition element coordination entity http://purl.obolibrary.org/obo/CHEBI_33497 transition element molecular entity http://purl.obolibrary.org/obo/CHEBI_35507 natural product fundamental parent http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_25585 nonmetal atom http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_33250 atom http://purl.obolibrary.org/obo/CHEBI_24782 imide http://purl.obolibrary.org/obo/CHEBI_33257 secondary amide http://purl.obolibrary.org/obo/CHEBI_33434 elemental halogen http://purl.obolibrary.org/obo/CHEBI_33259 elemental molecular entity http://purl.obolibrary.org/obo/CHEBI_26217 potassium molecular entity http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_26712 sodium molecular entity http://purl.obolibrary.org/obo/CHEBI_33296 alkali metal molecular entity http://purl.obolibrary.org/obo/CHEBI_26082 phosphorus molecular entity http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33302 pnictogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33459 pnictogen oxoanion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion http://purl.obolibrary.org/obo/CHEBI_25806 oxygen molecular entity http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_36902 chalcogen hydride http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity http://purl.obolibrary.org/obo/CHEBI_33304 chalcogen molecular entity http://purl.obolibrary.org/obo/CHEBI_22314 alkali metal atom http://purl.obolibrary.org/obo/CHEBI_33559 s-block element atom http://purl.obolibrary.org/obo/CHEBI_23378 copper cation http://purl.obolibrary.org/obo/CHEBI_37404 elemental copper http://purl.obolibrary.org/obo/CHEBI_33306 carbon group element atom http://purl.obolibrary.org/obo/CHEBI_33560 p-block element atom http://purl.obolibrary.org/obo/CHEBI_49319 carbocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_33598 carbocyclic compound http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon http://purl.obolibrary.org/obo/CHEBI_24471 halogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33582 carbon group molecular entity http://purl.obolibrary.org/obo/CHEBI_33675 p-block molecular entity http://purl.obolibrary.org/obo/CHEBI_25154 manganese molecular entity http://purl.obolibrary.org/obo/CHEBI_33743 manganese group molecular entity http://purl.obolibrary.org/obo/CHEBI_23377 copper molecular entity http://purl.obolibrary.org/obo/CHEBI_33745 copper group molecular entity http://purl.obolibrary.org/obo/CHEBI_33659 organic aromatic compound http://purl.obolibrary.org/obo/CHEBI_33655 aromatic compound http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_23114 chloride salt http://purl.obolibrary.org/obo/CHEBI_23117 chlorine molecular entity http://purl.obolibrary.org/obo/CHEBI_25900 aldopentose phosphate http://purl.obolibrary.org/obo/CHEBI_84055 pentose phosphate http://purl.obolibrary.org/obo/CHEBI_51337 organic sulfate salt http://purl.obolibrary.org/obo/CHEBI_24868 organic salt http://purl.obolibrary.org/obo/CHEBI_22601 arabinoside http://purl.obolibrary.org/obo/CHEBI_35312 pentoside http://purl.obolibrary.org/obo/CHEBI_36841 11-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_35350 hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_33485 chalcogen oxoanion http://purl.obolibrary.org/obo/CHEBI_35406 oxoanion http://purl.obolibrary.org/obo/CHEBI_35516 cholestane http://purl.obolibrary.org/obo/CHEBI_35508 steroid fundamental parent http://purl.obolibrary.org/obo/CHEBI_35902 oxo monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_25865 penicillanic acids http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid http://purl.obolibrary.org/obo/CHEBI_47811 penamcarboxylate http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion http://purl.obolibrary.org/obo/CHEBI_26079 phosphoric acid derivative http://purl.obolibrary.org/obo/CHEBI_36359 phosphorus oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_36359 phosphorus oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_36915 inorganic cation http://purl.obolibrary.org/obo/CHEBI_36916 cation http://purl.obolibrary.org/obo/CHEBI_36961 chalcocarbonic acid http://purl.obolibrary.org/obo/CHEBI_36962 organochalcogen compound http://purl.obolibrary.org/obo/CHEBI_50312 onium compound http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_37577 heteroatomic molecular entity http://purl.obolibrary.org/obo/CHEBI_23403 coumarins http://purl.obolibrary.org/obo/CHEBI_26004 phenylpropanoid http://purl.obolibrary.org/obo/CHEBI_38497 respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_38496 electron-transport chain inhibitor http://purl.obolibrary.org/obo/CHEBI_38502 cytochrome-bc1 complex inhibitor http://purl.obolibrary.org/obo/CHEBI_38497 respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_25355 mitochondrial respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_38497 respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_39146 trichostatin http://purl.obolibrary.org/obo/CHEBI_49319 carbocyclic antibiotic http://purl.obolibrary.org/obo/CHEBI_24712 hydroxymethyl group http://purl.obolibrary.org/obo/CHEBI_50325 proteinogenic amino-acid side-chain group http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride http://purl.obolibrary.org/obo/CHEBI_35881 pnictogen hydride http://purl.obolibrary.org/obo/CHEBI_33267 elemental nitrogen http://purl.obolibrary.org/obo/CHEBI_33465 elemental pnictogen http://purl.obolibrary.org/obo/CHEBI_23019 carbonyl group http://purl.obolibrary.org/obo/CHEBI_51422 organodiyl group http://purl.obolibrary.org/obo/CHEBI_30256 thiocarbonyl group http://purl.obolibrary.org/obo/CHEBI_51422 organodiyl group http://purl.obolibrary.org/obo/CHEBI_22390 alpha-D-glucoside http://purl.obolibrary.org/obo/CHEBI_35436 D-glucoside http://purl.obolibrary.org/obo/CHEBI_38012 aminoglycoside sulfate salt http://purl.obolibrary.org/obo/CHEBI_37852 organoammonium sulfate salt http://purl.obolibrary.org/obo/CHEBI_38261 imidazolidines http://purl.obolibrary.org/obo/CHEBI_38304 diazolidine http://purl.obolibrary.org/obo/CHEBI_38314 pyrazines http://purl.obolibrary.org/obo/CHEBI_38313 diazines http://purl.obolibrary.org/obo/CHEBI_46024 trichostatin A http://purl.obolibrary.org/obo/CHEBI_24650 hydroxamic acid http://purl.obolibrary.org/obo/CHEBI_39158 (R)-trichostatic acid http://purl.obolibrary.org/obo/CHEBI_39157 trichostatic acid http://purl.obolibrary.org/obo/CHEBI_39159 (S)-trichostatic acid http://purl.obolibrary.org/obo/CHEBI_39157 trichostatic acid http://purl.obolibrary.org/obo/CHEBI_39213 avermectin insecticide http://purl.obolibrary.org/obo/CHEBI_39220 avermectin pesticide http://purl.obolibrary.org/obo/CHEBI_39216 antibiotic acaricide http://purl.obolibrary.org/obo/CHEBI_22153 acaricide http://purl.obolibrary.org/obo/CHEBI_39219 avermectin acaricide http://purl.obolibrary.org/obo/CHEBI_39220 avermectin pesticide http://purl.obolibrary.org/obo/CHEBI_39209 macrolide insecticide http://purl.obolibrary.org/obo/CHEBI_39221 macrolide pesticide http://purl.obolibrary.org/obo/CHEBI_39218 macrolide acaricide http://purl.obolibrary.org/obo/CHEBI_39221 macrolide pesticide http://purl.obolibrary.org/obo/CHEBI_39220 avermectin pesticide http://purl.obolibrary.org/obo/CHEBI_39221 macrolide pesticide http://purl.obolibrary.org/obo/CHEBI_39231 emamectin B1a http://purl.obolibrary.org/obo/CHEBI_50346 emamectins http://purl.obolibrary.org/obo/CHEBI_39232 emamectin B1b http://purl.obolibrary.org/obo/CHEBI_50346 emamectins http://purl.obolibrary.org/obo/CHEBI_38496 electron-transport chain inhibitor http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor http://purl.obolibrary.org/obo/PATO_0002062 physical quality of a process http://purl.obolibrary.org/obo/PATO_0001236 process quality http://purl.obolibrary.org/obo/PHIPO_0001442 abnormal biological process phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype http://purl.obolibrary.org/obo/UBERON_6000004 panarthropod head http://purl.obolibrary.org/obo/UBERON_0000033 head http://purl.obolibrary.org/obo/UBERON_0035546 uveal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein https://purl.brain-bican.org/ontology/mbao/MBA_953 Pineal body https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0035237 branch of internal carotid artery http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment https://purl.brain-bican.org/ontology/mbao/MBA_141 Periventricular region http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/BFO_0000034 function http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition http://purl.obolibrary.org/obo/BFO_0000017 realizable entity http://purl.obolibrary.org/obo/BFO_0000019 quality http://purl.obolibrary.org/obo/BFO_0000020 specifically dependent continuant http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/BFO_0000031 generically dependent continuant http://purl.obolibrary.org/obo/IAO_0000027 data item http://purl.obolibrary.org/obo/IAO_0000030 information content entity http://purl.obolibrary.org/obo/CHEBI_38445 chromenone http://purl.obolibrary.org/obo/CHEBI_23232 chromenes http://purl.obolibrary.org/obo/CHEBI_22479 amino cyclitol glycoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_36988 5'-deoxyribonucleoside http://purl.obolibrary.org/obo/CHEBI_23636 deoxyribonucleoside http://purl.obolibrary.org/obo/CHEBI_47017 tetrahydrofuranol http://purl.obolibrary.org/obo/CHEBI_26912 oxolanes http://purl.obolibrary.org/obo/CHEBI_48376 carbamimidic acid http://purl.obolibrary.org/obo/CHEBI_48379 isourea http://purl.obolibrary.org/obo/CHEBI_23981 ethanolamines http://purl.obolibrary.org/obo/CHEBI_22478 amino alcohol http://purl.obolibrary.org/obo/CHEBI_38217 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid) http://purl.obolibrary.org/obo/CHEBI_36336 naphthalenesulfonic acid http://purl.obolibrary.org/obo/CHEBI_46686 azaalkane http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound http://purl.obolibrary.org/obo/CHEBI_27666 actinomycin D http://purl.obolibrary.org/obo/CHEBI_15369 actinomycin http://purl.obolibrary.org/obo/CHEBI_37624 L-glucose http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_37661 glucopyranose http://purl.obolibrary.org/obo/CHEBI_17234 glucose http://purl.obolibrary.org/obo/CHEBI_28417 gentamycin C http://purl.obolibrary.org/obo/CHEBI_17833 gentamycin http://purl.obolibrary.org/obo/CHEBI_22494 aminobenzoate http://purl.obolibrary.org/obo/CHEBI_22718 benzoates http://purl.obolibrary.org/obo/CHEBI_37404 elemental copper http://purl.obolibrary.org/obo/CHEBI_23377 copper molecular entity http://purl.obolibrary.org/obo/CHEBI_36823 pseudohalo group http://purl.obolibrary.org/obo/CHEBI_24433 group http://purl.obolibrary.org/obo/CHEBI_51144 nitrogen group http://purl.obolibrary.org/obo/CHEBI_24433 group http://purl.obolibrary.org/obo/CHEBI_48154 sulfur oxide http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity http://purl.obolibrary.org/obo/CHEBI_29281 alkyl sulfate http://purl.obolibrary.org/obo/CHEBI_26819 sulfuric ester http://purl.obolibrary.org/obo/CHEBI_23366 compatible osmolytes http://purl.obolibrary.org/obo/CHEBI_25728 osmolyte http://purl.obolibrary.org/obo/CHEBI_23089 chelate-forming peptide http://purl.obolibrary.org/obo/CHEBI_25903 peptide antibiotic http://purl.obolibrary.org/obo/CHEBI_25061 lipopeptide antibiotic http://purl.obolibrary.org/obo/CHEBI_46895 lipopeptide http://purl.obolibrary.org/obo/CHEBI_59064 colistin A http://purl.obolibrary.org/obo/CHEBI_59062 polymyxin http://purl.obolibrary.org/obo/CHEBI_59673 colistin B http://purl.obolibrary.org/obo/CHEBI_59062 polymyxin http://purl.obolibrary.org/obo/CHEBI_23239 chromopeptide http://purl.obolibrary.org/obo/CHEBI_25903 peptide antibiotic http://purl.obolibrary.org/obo/CHEBI_3371 capreomycin http://purl.obolibrary.org/obo/CHEBI_25903 peptide antibiotic http://purl.obolibrary.org/obo/CHEBI_30488 sulfonium http://purl.obolibrary.org/obo/CHEBI_33535 sulfur hydride http://purl.obolibrary.org/obo/CHEBI_42485 formyl group http://purl.obolibrary.org/obo/CHEBI_27207 univalent carboacyl group http://purl.obolibrary.org/obo/CHEBI_27412 gentamycin C1 http://purl.obolibrary.org/obo/CHEBI_28417 gentamycin C http://purl.obolibrary.org/obo/CHEBI_45599 dodecyl hydrogen sulfate http://purl.obolibrary.org/obo/CHEBI_29281 alkyl sulfate http://purl.obolibrary.org/obo/CHEBI_46883 carboxy group http://purl.obolibrary.org/obo/CHEBI_33249 organyl group http://purl.obolibrary.org/obo/CHEBI_35131 aldose phosphate http://purl.obolibrary.org/obo/CHEBI_33447 phospho sugar http://purl.obolibrary.org/obo/CHEBI_26045 phosphite ion http://purl.obolibrary.org/obo/CHEBI_33461 phosphorus oxoanion http://purl.obolibrary.org/obo/CHEBI_29192 hydrogenperoxide(1-) http://purl.obolibrary.org/obo/CHEBI_33693 oxygen hydride http://purl.obolibrary.org/obo/CHEBI_46912 ornithinium(1+) http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation http://purl.obolibrary.org/obo/CHEBI_46913 ornithinium(2+) http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation http://purl.obolibrary.org/obo/CHEBI_23636 deoxyribonucleoside http://purl.obolibrary.org/obo/CHEBI_33838 nucleoside http://purl.obolibrary.org/obo/CHEBI_26440 pyrimidine nucleoside http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines http://purl.obolibrary.org/obo/CHEBI_38597 triazole http://purl.obolibrary.org/obo/CHEBI_35727 triazoles http://purl.obolibrary.org/obo/CHEBI_13941 carbamate http://purl.obolibrary.org/obo/CHEBI_37022 amino-acid anion http://purl.obolibrary.org/obo/CHEBI_27242 uridines http://purl.obolibrary.org/obo/CHEBI_39446 pyrimidine ribonucleosides http://purl.obolibrary.org/obo/CHEBI_23872 dodecyl sulfate http://purl.obolibrary.org/obo/CHEBI_58958 organosulfate oxoanion http://purl.obolibrary.org/obo/CHEBI_26816 carbohydrate phosphate http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester http://purl.obolibrary.org/obo/CHEBI_29369 peroxy group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_43176 hydroxy group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_29785 nitro group http://purl.obolibrary.org/obo/CHEBI_51144 nitrogen group http://purl.obolibrary.org/obo/CHEBI_29922 sulfo group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_30106 azo group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_46629 oxo group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/CHEBI_33703 amino-acid cation http://purl.obolibrary.org/obo/CHEBI_25697 organic cation http://purl.obolibrary.org/obo/CHEBI_30096 diazene http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride http://purl.obolibrary.org/obo/CHEBI_30103 diazenide http://purl.obolibrary.org/obo/CHEBI_35106 nitrogen hydride http://purl.obolibrary.org/obo/CHEBI_29337 azanide http://purl.obolibrary.org/obo/CHEBI_79389 monovalent inorganic anion http://purl.obolibrary.org/obo/CHEBI_48819 cyano group http://purl.obolibrary.org/obo/CHEBI_36823 pseudohalo group http://purl.obolibrary.org/obo/CHEBI_33693 oxygen hydride http://purl.obolibrary.org/obo/CHEBI_36902 chalcogen hydride http://purl.obolibrary.org/obo/CHEBI_33535 sulfur hydride http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity http://purl.obolibrary.org/obo/CHEBI_28976 carbonic acid http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid http://purl.obolibrary.org/obo/CHEBI_46634 carbapenemcarboxylic acid http://purl.obolibrary.org/obo/CHEBI_25384 monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_50315 chloronium http://purl.obolibrary.org/obo/CHEBI_50313 onium cation http://purl.obolibrary.org/obo/CHEBI_33173 benzimidazolide http://purl.obolibrary.org/obo/CHEBI_50335 organic nitrogen anion http://purl.obolibrary.org/obo/CHEBI_29534 avermectin B1a http://purl.obolibrary.org/obo/CHEBI_50344 avermectin http://purl.obolibrary.org/obo/CHEBI_29537 avermectin B1b http://purl.obolibrary.org/obo/CHEBI_50344 avermectin http://purl.obolibrary.org/obo/CL_0000076 squamous epithelial cell http://purl.obolibrary.org/obo/CL_0000066 epithelial cell http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0000068 duct epithelial cell http://purl.obolibrary.org/obo/CL_0000377 tracheoblast http://purl.obolibrary.org/obo/CL_0000069 branched duct epithelial cell http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell http://purl.obolibrary.org/obo/CL_0000149 visual pigment cell http://purl.obolibrary.org/obo/CL_0000147 pigment cell http://purl.obolibrary.org/obo/CL_0000159 seromucus secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000447 carbohydrate secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000457 biogenic amine secreting cell http://purl.obolibrary.org/obo/CL_0000151 secretory cell http://purl.obolibrary.org/obo/CL_0000306 crystallin accumulating cell http://purl.obolibrary.org/obo/CL_0000325 stuff accumulating cell http://purl.obolibrary.org/obo/CL_0000327 extracellular matrix secreting cell http://purl.obolibrary.org/obo/CL_0000499 stromal cell http://purl.obolibrary.org/obo/CL_0001019 CD115-positive monocyte OR common dendritic progenitor http://purl.obolibrary.org/obo/CL_0002031 hematopoietic lineage restricted progenitor cell http://purl.obolibrary.org/obo/CL_0000995 CD34-positive, CD38-positive common myeloid progenitor OR CD34-positive, CD38-positive common lymphoid progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/CL_0001012 CD7-negative lymphoid progenitor OR granulocyte monocyte progenitor http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/CL_0000095 neuron associated cell http://purl.obolibrary.org/obo/CL_0002319 neural cell http://purl.obolibrary.org/obo/UBERON_0000005 chemosensory organ http://purl.obolibrary.org/obo/UBERON_0000020 sense organ http://purl.obolibrary.org/obo/UBERON_0035398 branch of external carotid artery http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/CHEBI_23449 cyclic peptide http://purl.obolibrary.org/obo/CHEBI_16670 peptide http://purl.obolibrary.org/obo/CHEBI_3992 cyclic ketone http://purl.obolibrary.org/obo/CHEBI_17087 ketone http://purl.obolibrary.org/obo/CHEBI_38218 isophthalonitrile http://purl.obolibrary.org/obo/CHEBI_18379 nitrile http://purl.obolibrary.org/obo/CHEBI_26509 quinoline alkaloid http://purl.obolibrary.org/obo/CHEBI_22315 alkaloid http://purl.obolibrary.org/obo/CHEBI_26416 pyridine alkaloid http://purl.obolibrary.org/obo/CHEBI_26421 pyridines http://purl.obolibrary.org/obo/CHEBI_26775 stilbene http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound http://purl.obolibrary.org/obo/CHEBI_9212 sparfloxacin http://purl.obolibrary.org/obo/CHEBI_87211 fluoroquinolone antibiotic http://purl.obolibrary.org/obo/CHEBI_24797 indole phytoalexin http://purl.obolibrary.org/obo/CHEBI_24828 indoles http://purl.obolibrary.org/obo/CHEBI_50346 emamectins http://purl.obolibrary.org/obo/CHEBI_25106 macrolide http://purl.obolibrary.org/obo/CHEBI_23955 erythronolide http://purl.obolibrary.org/obo/CHEBI_25106 macrolide http://purl.obolibrary.org/obo/CHEBI_25022 leucomycin http://purl.obolibrary.org/obo/CHEBI_25106 macrolide http://purl.obolibrary.org/obo/CHEBI_36336 naphthalenesulfonic acid http://purl.obolibrary.org/obo/CHEBI_33555 arenesulfonic acid http://purl.obolibrary.org/obo/CHEBI_41032 5-methyl[1,2,4]triazolo[3,4-b][1,3]benzothiazol-1-ium http://purl.obolibrary.org/obo/CHEBI_25697 organic cation http://purl.obolibrary.org/obo/CHEBI_46848 N-arylpiperazine http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound http://purl.obolibrary.org/obo/CHEBI_48589 piperidones http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound http://purl.obolibrary.org/obo/CHEBI_32066 Prothionamide http://purl.obolibrary.org/obo/CHEBI_26421 pyridines http://purl.obolibrary.org/obo/CHEBI_36757 farnesane sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_26658 sesquiterpenoid http://purl.obolibrary.org/obo/CHEBI_39270 naphthofuran http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle http://purl.obolibrary.org/obo/CHEBI_25605 nucleoside antibiotic http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent http://purl.obolibrary.org/obo/CHEBI_32964 ornithinate http://purl.obolibrary.org/obo/CHEBI_33558 alpha-amino-acid anion http://purl.obolibrary.org/obo/CHEBI_38180 polycyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_38179 monocyclic heteroarene http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_33570 benzenediols http://purl.obolibrary.org/obo/CHEBI_33853 phenols http://purl.obolibrary.org/obo/CHEBI_233202 paromomycin(5+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative http://purl.obolibrary.org/obo/CHEBI_48378 carboximidic acid http://purl.obolibrary.org/obo/CHEBI_48377 imidic acid http://purl.obolibrary.org/obo/CHEBI_48535 aryloxypyrimidine http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines http://purl.obolibrary.org/obo/CHEBI_47881 3-oxo monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35871 oxo monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35983 7-oxo monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_35871 oxo monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_32158 streptomycin sulfate http://purl.obolibrary.org/obo/CHEBI_38012 aminoglycoside sulfate salt http://purl.obolibrary.org/obo/CHEBI_37852 organoammonium sulfate salt http://purl.obolibrary.org/obo/CHEBI_51337 organic sulfate salt http://purl.obolibrary.org/obo/CHEBI_38418 1,3-thiazoles http://purl.obolibrary.org/obo/CHEBI_48901 thiazoles http://purl.obolibrary.org/obo/CHEBI_8733 Quinupristin-dalfopristin http://purl.obolibrary.org/obo/CHEBI_50860 organic molecular entity http://purl.obolibrary.org/obo/CHEBI_16733 D-alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_83925 non-proteinogenic alpha-amino acid http://purl.obolibrary.org/obo/CHEBI_39446 pyrimidine ribonucleosides http://purl.obolibrary.org/obo/CHEBI_18254 ribonucleoside http://purl.obolibrary.org/obo/CHEBI_45367 rifabutin http://purl.obolibrary.org/obo/CHEBI_26580 rifamycins http://purl.obolibrary.org/obo/CHEBI_50011 Calcofluor White http://purl.obolibrary.org/obo/CHEBI_38700 organic sodium salt http://purl.obolibrary.org/obo/CHEBI_33791 canonical nucleoside residue http://purl.obolibrary.org/obo/CHEBI_50320 nucleoside residue http://purl.obolibrary.org/obo/CHEBI_39157 trichostatic acid http://purl.obolibrary.org/obo/CHEBI_35983 7-oxo monocarboxylic acid http://purl.obolibrary.org/obo/CHEBI_24583 hexitol http://purl.obolibrary.org/obo/CHEBI_17522 alditol http://purl.obolibrary.org/obo/CHEBI_48848 erythronolide A http://purl.obolibrary.org/obo/CHEBI_23955 erythronolide http://purl.obolibrary.org/obo/CHEBI_30911 glucitol http://purl.obolibrary.org/obo/CHEBI_24583 hexitol http://purl.obolibrary.org/obo/CHEBI_23953 erythromycins http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic http://purl.obolibrary.org/obo/CHEBI_39221 macrolide pesticide http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic http://purl.obolibrary.org/obo/CHEBI_9321 sulbactam http://purl.obolibrary.org/obo/CHEBI_25865 penicillanic acids http://purl.obolibrary.org/obo/CHEBI_37734 phosphoric ester http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_47857 ureas http://purl.obolibrary.org/obo/CHEBI_33256 primary amide http://purl.obolibrary.org/obo/CHEBI_29214 sulfonic acid http://purl.obolibrary.org/obo/CHEBI_33402 sulfur oxoacid http://purl.obolibrary.org/obo/CHEBI_48854 sulfurous acid http://purl.obolibrary.org/obo/CHEBI_33402 sulfur oxoacid http://purl.obolibrary.org/obo/CHEBI_18140 hydrogen halide http://purl.obolibrary.org/obo/CHEBI_33405 hydracid http://purl.obolibrary.org/obo/CHEBI_36856 hydrogen isocyanide http://purl.obolibrary.org/obo/CHEBI_33405 hydracid http://purl.obolibrary.org/obo/CHEBI_36361 phosphorous acid http://purl.obolibrary.org/obo/CHEBI_33457 phosphorus oxoacid http://purl.obolibrary.org/obo/CHEBI_17137 hydrogensulfite http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion http://purl.obolibrary.org/obo/CHEBI_45696 hydrogensulfate http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion http://purl.obolibrary.org/obo/CHEBI_29919 hydrosulfide http://purl.obolibrary.org/obo/CHEBI_33535 sulfur hydride http://purl.obolibrary.org/obo/CHEBI_23213 choline ester http://purl.obolibrary.org/obo/CHEBI_35701 ester http://purl.obolibrary.org/obo/CHEBI_51121 fluorescent dye http://purl.obolibrary.org/obo/CHEBI_37958 dye http://purl.obolibrary.org/obo/CHEBI_46687 diazaalkane http://purl.obolibrary.org/obo/CHEBI_39474 polyazaalkane http://purl.obolibrary.org/obo/CHEBI_48355 non-polar solvent http://purl.obolibrary.org/obo/CHEBI_46787 solvent http://purl.obolibrary.org/obo/CHEBI_50297 canonical nucleotide residue http://purl.obolibrary.org/obo/CHEBI_50319 nucleotide residue http://purl.obolibrary.org/obo/CHEBI_24753 hygromycin http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic http://purl.obolibrary.org/obo/CHEBI_26788 streptomycins http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic http://purl.obolibrary.org/obo/CHEBI_24951 kanamycins http://purl.obolibrary.org/obo/CHEBI_22507 aminoglycoside antibiotic http://purl.obolibrary.org/obo/CHEBI_33431 elemental chlorine http://purl.obolibrary.org/obo/CHEBI_33434 elemental halogen http://purl.obolibrary.org/obo/CHEBI_17630 kanamycin A http://purl.obolibrary.org/obo/CHEBI_24951 kanamycins http://purl.obolibrary.org/obo/CHEBI_28098 kanamycin B http://purl.obolibrary.org/obo/CHEBI_24951 kanamycins http://purl.obolibrary.org/obo/CHEBI_26830 sulfonium compound http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity http://purl.obolibrary.org/obo/CHEBI_33402 sulfur oxoacid http://purl.obolibrary.org/obo/CHEBI_33484 chalcogen oxoacid http://purl.obolibrary.org/obo/CHEBI_33482 sulfur oxoanion http://purl.obolibrary.org/obo/CHEBI_33485 chalcogen oxoanion http://purl.obolibrary.org/obo/CHEBI_33424 sulfur oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_33241 oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_29277 dinitride(2-) http://purl.obolibrary.org/obo/CHEBI_33266 diatomic nitrogen http://purl.obolibrary.org/obo/CHEBI_18291 manganese atom http://purl.obolibrary.org/obo/CHEBI_33352 manganese group element atom http://purl.obolibrary.org/obo/CHEBI_33695 information biomacromolecule http://purl.obolibrary.org/obo/CHEBI_33694 biomacromolecule http://purl.obolibrary.org/obo/CHEBI_41609 carbonate http://purl.obolibrary.org/obo/CHEBI_35604 carbon oxoanion http://purl.obolibrary.org/obo/CHEBI_19129 11alpha-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_36841 11-hydroxy steroid http://purl.obolibrary.org/obo/CHEBI_51256 amoxicillin(1-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_30938 6-aminopenicillanate http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_50658 ampicillin(1-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_51354 benzylpenicillin(1-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_51897 carbenicillin(2-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_52064 methicillin(1-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_52132 oxacillin(1-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_52433 piperacillin(1-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_51959 organic tricyclic compound http://purl.obolibrary.org/obo/CHEBI_51958 organic polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33266 diatomic nitrogen http://purl.obolibrary.org/obo/CHEBI_33267 elemental nitrogen http://purl.obolibrary.org/obo/CHEBI_33552 sulfonic acid derivative http://purl.obolibrary.org/obo/CHEBI_33424 sulfur oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_33432 monoatomic chlorine http://purl.obolibrary.org/obo/CHEBI_33433 monoatomic halogen http://purl.obolibrary.org/obo/CHEBI_33340 zinc group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_33352 manganese group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_33661 monocyclic compound http://purl.obolibrary.org/obo/CHEBI_33595 cyclic compound http://purl.obolibrary.org/obo/CHEBI_33842 aromatic annulene http://purl.obolibrary.org/obo/CHEBI_33847 monocyclic arene http://purl.obolibrary.org/obo/CHEBI_33608 hydrogen molecular entity http://purl.obolibrary.org/obo/CHEBI_33674 s-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33673 zinc group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33743 manganese group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_33745 copper group molecular entity http://purl.obolibrary.org/obo/CHEBI_33676 d-block molecular entity http://purl.obolibrary.org/obo/CHEBI_37176 mononuclear parent hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_37175 organic hydride http://purl.obolibrary.org/obo/CHEBI_33692 hydrides http://purl.obolibrary.org/obo/CHEBI_33719 alpha-amino-acid cation http://purl.obolibrary.org/obo/CHEBI_33703 amino-acid cation http://purl.obolibrary.org/obo/CHEBI_33700 proteinogenic amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33710 alpha-amino-acid residue http://purl.obolibrary.org/obo/CHEBI_33792 canonical ribonucleoside residue http://purl.obolibrary.org/obo/CHEBI_33791 canonical nucleoside residue http://purl.obolibrary.org/obo/CHEBI_35296 ortho-fused polycyclic arene http://purl.obolibrary.org/obo/CHEBI_35427 ortho-fused polycyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_47019 dihydroxytetrahydrofuran http://purl.obolibrary.org/obo/CHEBI_47017 tetrahydrofuranol http://purl.obolibrary.org/obo/CHEBI_50299 canonical ribonucleotide residue http://purl.obolibrary.org/obo/CHEBI_50297 canonical nucleotide residue http://purl.obolibrary.org/obo/CHEBI_31927 nystatin A3 http://purl.obolibrary.org/obo/CHEBI_59676 nystatins http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_1 root http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://purl.obolibrary.org/obo/NCBITaxon_862507 Mus http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_7898 Actinopterygii http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_8287 Sarcopterygii http://purl.obolibrary.org/obo/NCBITaxon_117571 Euteleostomi http://purl.obolibrary.org/obo/NCBITaxon_88770 Panarthropoda http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_131567 cellular organisms http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_41665 Neopterygii http://purl.obolibrary.org/obo/NCBITaxon_186623 Actinopteri http://purl.obolibrary.org/obo/NCBITaxon_6960 Hexapoda http://purl.obolibrary.org/obo/NCBITaxon_197562 Pancrustacea http://purl.obolibrary.org/obo/NCBITaxon_197562 Pancrustacea http://purl.obolibrary.org/obo/NCBITaxon_197563 Mandibulata http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_2759 Eukaryota http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://purl.obolibrary.org/obo/NCBITaxon_314147 Glires http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_32523 Tetrapoda http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32524 Amniota http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_4751 Fungi http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33154 Opisthokonta http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/NCBITaxon_33208 Metazoa http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_1206794 Ecdysozoa http://purl.obolibrary.org/obo/NCBITaxon_33317 Protostomia http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_33511 Deuterostomia http://purl.obolibrary.org/obo/NCBITaxon_10066 Muridae http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_10088 Mus http://purl.obolibrary.org/obo/NCBITaxon_39107 Murinae http://purl.obolibrary.org/obo/NCBITaxon_32525 Theria http://purl.obolibrary.org/obo/NCBITaxon_40674 Mammalia http://purl.obolibrary.org/obo/NCBITaxon_32443 Teleostei http://purl.obolibrary.org/obo/NCBITaxon_41665 Neopterygii http://purl.obolibrary.org/obo/NCBITaxon_33213 Bilateria http://purl.obolibrary.org/obo/NCBITaxon_6072 Eumetazoa http://purl.obolibrary.org/obo/NCBITaxon_197563 Mandibulata http://purl.obolibrary.org/obo/NCBITaxon_6656 Arthropoda http://purl.obolibrary.org/obo/NCBITaxon_50557 Insecta http://purl.obolibrary.org/obo/NCBITaxon_6960 Hexapoda http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_7711 Chordata http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_117570 Teleostomi http://purl.obolibrary.org/obo/NCBITaxon_7776 Gnathostomata http://purl.obolibrary.org/obo/NCBITaxon_186623 Actinopteri http://purl.obolibrary.org/obo/NCBITaxon_7898 Actinopterygii http://purl.obolibrary.org/obo/NCBITaxon_1338369 Dipnotetrapodomorpha http://purl.obolibrary.org/obo/NCBITaxon_8287 Sarcopterygii http://purl.obolibrary.org/obo/NCBITaxon_10090 Mus musculus http://purl.obolibrary.org/obo/NCBITaxon_862507 Mus http://purl.obolibrary.org/obo/NCBITaxon_6656 Arthropoda http://purl.obolibrary.org/obo/NCBITaxon_88770 Panarthropoda http://purl.obolibrary.org/obo/NCBITaxon_7742 Vertebrata http://purl.obolibrary.org/obo/NCBITaxon_89593 Craniata http://purl.obolibrary.org/obo/NCBITaxon_1437010 Boreoeutheria http://purl.obolibrary.org/obo/NCBITaxon_9347 Eutheria http://purl.obolibrary.org/obo/UBERON_0000153 anterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0000154 posterior region of body http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0036186 fibroelastic connective tissue http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0000963 head sensillum http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum http://purl.obolibrary.org/obo/UBERON_0034994 hindbrain cortical intermediate zone http://purl.obolibrary.org/obo/UBERON_0004040 cortical intermediate zone http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer https://purl.brain-bican.org/ontology/mbao/MBA_73 ventricular systems http://purl.obolibrary.org/obo/UBERON_0005281 ventricular system of central nervous system http://purl.obolibrary.org/obo/UBERON_0036290 myocardium of anterior wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0006566 left ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0036291 myocardium of anterior wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0006567 right ventricle myocardium http://purl.obolibrary.org/obo/CLM_1000043 NS forest marker set of pulmonary neuroendocrine cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000056 NS forest marker set of tracheobronchial smooth muscle cell (Human lung). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000074 NS forest marker set of lamp5 GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000075 NS forest marker set of Lamp5 Lhx6 neuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000082 NS forest marker set of sst GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000083 NS forest marker set of sst chodl GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/CLM_1000085 NS forest marker set of VIP GABAergic interneuron (Human neocortex). http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/NCBITaxon_337687 Muroidea http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/CHEBI_35313 hexoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_35312 pentoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_47779 aminoglycoside http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_48891 thiazolidinone http://purl.obolibrary.org/obo/CHEBI_35622 thiazolidines http://purl.obolibrary.org/obo/CHEBI_46812 1,3-oxazoles http://purl.obolibrary.org/obo/CHEBI_35790 oxazole http://purl.obolibrary.org/obo/CHEBI_43254 (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone http://purl.obolibrary.org/obo/CHEBI_46920 N-methylpiperazine http://purl.obolibrary.org/obo/CHEBI_46845 N-alkylpiperazine http://purl.obolibrary.org/obo/CHEBI_25478 naphthalenesulfonate http://purl.obolibrary.org/obo/CHEBI_22713 arenesulfonate oxoanion http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_27081 transition element atom http://purl.obolibrary.org/obo/CHEBI_36566 zinc coordination entity http://purl.obolibrary.org/obo/CHEBI_36563 zinc group coordination entity http://purl.obolibrary.org/obo/CHEBI_28694 copper atom http://purl.obolibrary.org/obo/CHEBI_88184 metal allergen http://purl.obolibrary.org/obo/CHEBI_46850 organoammonium salt http://purl.obolibrary.org/obo/CHEBI_35276 ammonium compound http://purl.obolibrary.org/obo/CHEBI_36828 pseudohalide anion http://purl.obolibrary.org/obo/CHEBI_36829 polyatomic monoanion http://purl.obolibrary.org/obo/CHEBI_8309 polymyxin B1 http://purl.obolibrary.org/obo/CHEBI_59062 polymyxin http://purl.obolibrary.org/obo/CHEBI_83708 (R)-flutriafol http://purl.obolibrary.org/obo/CHEBI_83707 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol http://purl.obolibrary.org/obo/CHEBI_83709 (S)-flutriafol http://purl.obolibrary.org/obo/CHEBI_83707 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol http://purl.obolibrary.org/obo/UBERON_0036288 anterior wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0036285 wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0001033 gustatory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system The sensory system for the sense of taste. http://purl.obolibrary.org/obo/UBERON_0001040 yolk sac http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]. http://purl.obolibrary.org/obo/UBERON_0001041 foregut http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract Anterior subdivision of a digestive tract. http://purl.obolibrary.org/obo/UBERON_0001042 chordate pharynx http://purl.obolibrary.org/obo/UBERON_0006562 pharynx A portion of the respiratory and digestive tracts; its distal limit is the superior part of the esophagus and it connects the nasal and oral cavities with the esophagus and larynx; it contains the valleculae and the pyriform recesses; its upper limits are the nasal cavity and cranial base.[FEED]. http://purl.obolibrary.org/obo/UBERON_0001048 primordium http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Primordia are populations of contiguous cells that are morphologically distinct and already correspond in extent to a later organ/tissue[FBbt, Hartenstein, V. (2004)]. http://purl.obolibrary.org/obo/UBERON_0001049 neural tube http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system In the developing vertebrate, the neural tube is the embryo's precursor to the central nervous system, which comprises the brain and spinal cord. The neural groove gradually deepens as the neural folds become elevated, and ultimately the folds meet and coalesce in the middle line and convert the groove into a closed tube, the neural tube or neural canal (which strictly speaking is the center of the neural tube), the ectodermal wall of which forms the rudiment of the nervous system. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001062 anatomical entity http://purl.obolibrary.org/obo/BFO_0000004 independent continuant Biological entity that is either an individual member of a biological species or constitutes the structural organization of an individual member of a biological species. http://purl.obolibrary.org/obo/UBERON_0001068 skin of back http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A zone of skin that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001070 external carotid artery http://purl.obolibrary.org/obo/UBERON_0005396 carotid artery segment A terminal branch of the left or right common carotid artery which supplies oxygenated blood to to the throat, neck glands, tongue, face, mouth, ear, scalp and dura mater of the meninges[MP]. http://purl.obolibrary.org/obo/UBERON_0001071 superficial cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery It ascends beneath the anterior margin of the trapezius, distributing branches to it, and to the neighboring muscles and lymph glands in the neck, and anastomosing with the superficial branch of the descending branch of the occipital artery. http://purl.obolibrary.org/obo/UBERON_0001072 inferior vena cava http://purl.obolibrary.org/obo/UBERON_0004087 vena cava A vein that carries deoxygenated blood from the lower half of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0001074 pericardial cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity A potential space between the visceral and parietal layers of the pericardium. http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002165 endocardium Endocardium that is part of the cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0001082 epicardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002348 epicardium An epicardial layer that lines a cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle http://purl.obolibrary.org/obo/UBERON_0002349 myocardium Muscular layer of the cardiac ventricle composed of a compact myocardial layer surrounding the trabecular layer. http://purl.obolibrary.org/obo/UBERON_0001084 skin of head http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin A zone of skin that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001087 pleural fluid http://purl.obolibrary.org/obo/UBERON_0036244 secretion of serous membrane Transudate contained in the pleural cavity. http://purl.obolibrary.org/obo/UBERON_0001090 synovial fluid http://purl.obolibrary.org/obo/UBERON_0007794 secretion of serous gland Joint fluid is a transudate of plasma that is actively secreted by synovial cells. http://purl.obolibrary.org/obo/UBERON_0001096 wall of esophagus http://purl.obolibrary.org/obo/UBERON_0000328 gut wall An anatomical wall that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue http://purl.obolibrary.org/obo/UBERON_8600006 visceral striated muscle tissue Muscle tissue composed of cardiac muscle cells, forming the muscles of the heart[ZFA,modified]. http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium Simple squamous epithelium of mesodermal origin which lines serous membranes. Examples: mesothelium of pleura, mesothelium of peritoneum[FMA]. Wikipedia: The mesothelium is a membrane that forms the lining of several body cavities: the pleura (thoracal cavity), peritoneum (abdominal cavity including the mesentery) and pericardium (heart sac). Mesothelial tissue also surrounds the male internal reproductive organs (the tunica vaginalis testis) and covers the internal reproductive organs of women (the tunica serosa uteri). http://purl.obolibrary.org/obo/UBERON_0001137 dorsum http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that is the entire part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. In vertebrares this includes the vertebral column.. http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vein that carries deoxygenated blood from its corresponding ovary to inferior vena cava or one of its tributaries. http://purl.obolibrary.org/obo/UBERON_0001178 visceral peritoneum http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane The inner layer of peritoneum that is wrapped around organs located inside the intraperitoneal space. http://purl.obolibrary.org/obo/UBERON_0001179 peritoneal cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity Anatomical cavity bounded by visceral and parietal peritoneum. http://purl.obolibrary.org/obo/UBERON_0001190 ovarian artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies an ovary. http://purl.obolibrary.org/obo/UBERON_0001268 peritoneal fluid http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid Transudate contained in the peritoneal cavity. http://purl.obolibrary.org/obo/UBERON_0001359 cerebrospinal fluid http://purl.obolibrary.org/obo/UBERON_0007779 transudate A clear, colorless, bodily fluid, that occupies the subarachnoid space and the ventricular system around and inside the brain and spinal cord. http://purl.obolibrary.org/obo/UBERON_0001366 parietal peritoneum http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane The outer layer of peritoneum that is attached to the abdominal and pelvic walls. http://purl.obolibrary.org/obo/UBERON_0001416 skin of abdomen http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin A zone of skin that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001417 skin of neck http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001418 skin of thorax http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A zone of skin that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001421 pectoral girdle region http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes the pectoral girdle skeleton and associated soft tissue. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). Examples: There are only two instances in an organism, right and left pectoral girdle regions. http://purl.obolibrary.org/obo/UBERON_0001434 skeletal system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical system that is a multi-element, multi-tissue anatomical cluster that consists of the skeleton and the articular system. http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip http://purl.obolibrary.org/obo/UBERON_1000021 skin of face A zone of skin that is part of a lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001474 bone element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of bone tissue. http://purl.obolibrary.org/obo/UBERON_0001484 articular capsule http://purl.obolibrary.org/obo/UBERON_0000094 membrane organ An articular capsule (or joint capsule) is an envelope surrounding a synovial joint. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001496 ascending aorta http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta[GO]. A portion of the aorta commencing at the upper part of the base of the left ventricle, on a level with the lower border of the third costal cartilage behind the left half of the sternum; it passes obliquely upward, forward, and to the right, in the direction of the heart's axis, as high as the upper border of the second right costal cartilage, describing a slight curve in its course, and being situated, about 6 cm behind the posterior surface of the sternum. The total length is about 5 cm in length [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0001508 arch of aorta http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta The convex portion of the aorta between the ascending and descending parts of the aorta; branches from it include the brachiocephalic trunk, the left common carotid artery, and the left subclavian artery; the brachiocephalic trunk further splits to form the right subclavian artery and the right common carotid artery. http://purl.obolibrary.org/obo/UBERON_0001514 descending aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries[GO]. The descending aorta is part of the aorta, the largest artery in the body. The descending aorta is the part of the aorta beginning at the aortic arch that runs down through the chest and abdomen. The descending aorta is divided into two portions, the thoracic and abdominal, in correspondence with the two great cavities of the trunk in which it is situated. Within the abdomen, the descending aorta branches into the two common iliac arteries which serve the legs. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001515 thoracic aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta The part of the aorta that extends from the origin at the heart to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest. http://purl.obolibrary.org/obo/UBERON_0001516 abdominal aorta http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta Abdominal part of aorta: the distal part of the descending aorta, which is the continuation of the thoracic part and gives rise to the inferior phrenic, lumbar, median sacral, superior and inferior mesenteric, middle suprarenal, renal, and testicular or ovarian arteries, and celiac trunk[BTO]. The abdominal aorta is the largest artery in the abdominal cavity. As part of the aorta, it is a direct continuation of descending aorta(of the thorax). [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001529 brachiocephalic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery The short first aortic arch branch and divides into the right subclavian artery and the right common carotid artery. http://purl.obolibrary.org/obo/UBERON_0001530 common carotid artery plus branches http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A bilaterally paired branched artery that originates from the aortic arches and divides into and includes as parts the internal and external carotid arteries[cjm]. http://purl.obolibrary.org/obo/UBERON_0001531 right common carotid artery plus branches http://purl.obolibrary.org/obo/UBERON_0001530 common carotid artery plus branches The rightmost of the two common carotid arteries, originating from in the neck from the brachiocephalic trunk. http://purl.obolibrary.org/obo/UBERON_0001532 internal carotid artery http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A terminal branch of the left or right common carotid artery which supplies oxygenated blood to the brain and eyes[MP]. http://purl.obolibrary.org/obo/UBERON_0001533 subclavian artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of two laterally paired arteries that supplies the pectoral appendages, usually branching from the dorsal aorta. http://purl.obolibrary.org/obo/UBERON_0001534 right subclavian artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The subclavian artery that supplies the right pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0001536 left common carotid artery plus branches http://purl.obolibrary.org/obo/UBERON_0001530 common carotid artery plus branches The leftmost of the two common carotid arteries, originating from the aortic arch in the thorax. http://purl.obolibrary.org/obo/UBERON_0001555 digestive tract http://purl.obolibrary.org/obo/UBERON_0000025 tube A tube extending from the mouth to the anus. http://purl.obolibrary.org/obo/UBERON_0001568 muscle of larynx http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle The muscles associated with the larynx. http://purl.obolibrary.org/obo/UBERON_0001571 genioglossus muscle http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Either of a pair of lingual muscles with origin in the mandible, with insertion to the lingual fascia below the mucous membrane and epiglottis, with nerve supply from the hypoglossal nerve, and whose action depresses and protrudes the tongue. http://purl.obolibrary.org/obo/UBERON_0001572 hyoglossus muscle http://purl.obolibrary.org/obo/UBERON_0001575 extrinsic muscle of tongue A muscle that attaches to the hyopid bone and to the tongue and is innervated by cranial nerve XII. http://purl.obolibrary.org/obo/UBERON_0001575 extrinsic muscle of tongue http://purl.obolibrary.org/obo/UBERON_0000378 tongue muscle A muscle organ that attaches the tongue to some other structure. http://purl.obolibrary.org/obo/UBERON_0001576 intrinsic muscle of tongue http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The intrinsic tongue muscles are an integral part of the tongue and completely contained within the tongue that are innervated by Cranial Nerve XII. http://purl.obolibrary.org/obo/UBERON_0001584 left subclavian artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The subclavian artery that supplies the left pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0001586 internal jugular vein http://purl.obolibrary.org/obo/UBERON_0004711 jugular vein One of two jugular veins that collect the blood from the brain, the superficial parts of the face, and the neck. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001592 bronchial vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The bronchial veins are small vessels that return blood from the larger bronchi and structures at the roots of the lungs. The right side drains into the azygos vein, while the left side drains into the left superior intercostal vein or the accessory hemiazygos vein. The bronchial veins are counterparts to the bronchial arteries. The veins, however, do not return all of the blood supplied by the arteries; much of the blood that is carried in the bronchial arteries is returned to the heart via the pulmonary veins. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001593 venous plexus http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus A congregation of multiple veins. http://purl.obolibrary.org/obo/UBERON_0001605 ciliary muscle http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle The ciliary muscle is a ring of smooth muscle in the middle layer of the eye that controls the eye's accommodation for viewing objects at varying distances and regulates the flow of aqueous humour through Schlemm's canal. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001610 lingual artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The lingual artery arises from the external carotid between the superior thyroid and facial artery[WP]. http://purl.obolibrary.org/obo/UBERON_0001612 facial artery http://purl.obolibrary.org/obo/UBERON_0035398 branch of external carotid artery A branch of the external carotid artery that supplies structures of the face. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001616 maxillary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that supplies deep structures of the face. It comes just out behind the neck of the mandible. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001628 posterior communicating artery http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of a pair of right-sided and left-sided blood vessels in the circle of Willis. It connects the three cerebral arteries of the same side. Anteriorly, it is one portion of the terminal trifurcation of the internal carotid artery. The anterior cerebral artery and the middle cerebral artery are the other two branches of the trifurcation. Posteriorly, it communicates with the posterior cerebral artery. http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure Organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work[GO]. http://purl.obolibrary.org/obo/UBERON_0001651 right pulmonary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The pulmonary artery that supplies the right lung. http://purl.obolibrary.org/obo/UBERON_0001652 left pulmonary artery http://purl.obolibrary.org/obo/UBERON_0001637 artery The pulmonary artery that supplies the left lung. http://purl.obolibrary.org/obo/UBERON_0001653 facial vein http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein The anterior facial vein (facial vein) commences at the side of the root of the nose, and is a direct continuation of the angular vein where it also receives a small nasal branch. It lies behind the facial artery and follows a less tortuous course. It receives blood from the external palatine vein before it either joins the anterior branch of the retromandibular vein to form the common facial vein, or drains directly into the internal jugular vein. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001663 cerebral vein http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel The cerebral veins are divisible into external and internal groups according to the outer surfaces or the inner parts of the hemispheres they drain into. The external veins are the superior cerebral veins, inferior cerebral veins, and middle cerebral vein. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001668 cerebellar vein http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains the cerebellum. http://purl.obolibrary.org/obo/UBERON_0001675 trigeminal ganglion http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The cranial ganglion that is associated with and extends fibers into the trigeminal nerve. http://purl.obolibrary.org/obo/UBERON_0001676 occipital bone http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone The bone at the lower, posterior part of the skull. http://purl.obolibrary.org/obo/UBERON_0001678 temporal bone http://purl.obolibrary.org/obo/UBERON_0008193 pneumatized bone The large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous. http://purl.obolibrary.org/obo/UBERON_0001685 hyoid bone http://purl.obolibrary.org/obo/UBERON_0008001 irregular bone A horseshoe shaped bone situated in the anterior midline of the neck between the chin and the thyroid cartilage. The hyoid bone provides attachment to the muscles of the floor of the mouth and the tongue above, the larynx below, and the epiglottis and pharynx behind. [WP,modified]. http://purl.obolibrary.org/obo/UBERON_0001701 glossopharyngeal ganglion http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglion The group of neuron cell bodies associated with the ninth cranial nerve. http://purl.obolibrary.org/obo/UBERON_0001703 neurocranium http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull Subdivision of skeletal system that surrounds and protects the brain. Includes the skull base, sensory capsules and the central part of the skull roof. http://purl.obolibrary.org/obo/UBERON_0001710 lower jaw region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of head that consists of the lower jaw skeletal elements plus associated soft tissue (skin, lips, muscle)[cjm]. http://purl.obolibrary.org/obo/UBERON_0001714 cranial ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion The groups of nerve cell bodies associated with the twelve cranial nerves. http://purl.obolibrary.org/obo/UBERON_0001725 cranial synchondrosis http://purl.obolibrary.org/obo/UBERON_0002215 synchondrosis The cartilaginous joints of the skull; these include sphenoethmoidal synchondrosis, sphenooccipital synchondrosis, sphenopetrosal synchondrosis, petrooccipital synchondrosis, anterior intraoccipital synchondrosis and posterior intraoccipital synchondrosis. http://purl.obolibrary.org/obo/UBERON_0001727 taste bud http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure A specialized receptor organ that is a collection of cells spanning the gustatory epithelium. http://purl.obolibrary.org/obo/UBERON_0001731 cavity of pharynx http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a pharynx. http://purl.obolibrary.org/obo/UBERON_0001766 anterior chamber of eyeball http://purl.obolibrary.org/obo/UBERON_0006311 chamber of eyeball The space in the eye, filled with aqueous humor, and bounded anteriorly by the cornea and a small portion of the sclera and posteriorly by a small portion of the ciliary body, the iris, and part of the crystalline lens. http://purl.obolibrary.org/obo/UBERON_0001772 corneal epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium The smooth stratified squamous epithelium that covers the outer surface of the cornea. http://purl.obolibrary.org/obo/UBERON_0001773 sclera http://purl.obolibrary.org/obo/UBERON_0000064 organ part Opaque fibrous outer layer of the eyeball[ZFA,Kardong,WP]. http://purl.obolibrary.org/obo/UBERON_0001774 skeletal muscle of trunk http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A skeletal muscle organ that is part of the trunk region. http://purl.obolibrary.org/obo/UBERON_0001777 substantia propria of cornea http://purl.obolibrary.org/obo/UBERON_0003891 stroma The lamellated connective tissue of the cornea between the Bowman and Descemet membranes. http://purl.obolibrary.org/obo/UBERON_0001778 ciliary epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A double layer covering the ciliary body that produces aqueous humor. http://purl.obolibrary.org/obo/UBERON_0001779 iris stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma The delicate vascular connective tissue that lies between the anterior surface of the iris and the pars iridica retinae. http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve The any of the paired peripheral nerves formed by the union of the dorsal and ventral spinal roots from each spinal cord segment[MP,modified]. http://purl.obolibrary.org/obo/UBERON_0001781 layer of retina http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Any of the layers that make up the retina[MP]. http://purl.obolibrary.org/obo/UBERON_0001796 aqueous humor of eyeball http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid A thick watery refractive medium that fills the space between the lens and the cornea[WP]. http://purl.obolibrary.org/obo/UBERON_0001800 sensory ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion The clusters of neurons in the somatic peripheral nervous system which contain the cell bodies of sensory nerve axons, interneurons and non-neuronal supporting cells. http://purl.obolibrary.org/obo/UBERON_0001801 anterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any of the parts of the eye that lie in front of, or ventral to, the lens (inclusive). http://purl.obolibrary.org/obo/UBERON_0001802 posterior segment of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any of the parts of the eye that lie in back of, or dorsal to, the lens (but not inclusive). http://purl.obolibrary.org/obo/UBERON_0001803 epithelium of lens http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A layer of epithelial cells that is part of the eye. http://purl.obolibrary.org/obo/UBERON_0001804 capsule of lens http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane The elastic, clear, membrane-like structure, that is outer most layer of the lens. http://purl.obolibrary.org/obo/UBERON_0001805 autonomic ganglion http://purl.obolibrary.org/obo/UBERON_0003338 ganglion of peripheral nervous system Ganglion that has dendrites that form a junction between autonomic nerves originating from the central nervous system and autonomic nerves innervating their target organs in the periphery. There are two subtypes, sympathetic ganglion and parasympathetic ganglion. http://purl.obolibrary.org/obo/UBERON_0001806 sympathetic ganglion http://purl.obolibrary.org/obo/UBERON_0001805 autonomic ganglion A ganglion of the sympathetic nervous system. Examples: paravertebral and the prevertebral ganglia, which include the sympathetic chain ganglia, the superior, middle, and inferior cervical ganglia, and the aorticorenal, celiac, and stellate ganglia. http://purl.obolibrary.org/obo/UBERON_0001808 parasympathetic ganglion http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Ganglion containing neurons that receive innervation from parasympathetic neurons in the central nervous system and subserves parasympathetic functions through innervation of smooth muscle, cardiac muscle and glands. http://purl.obolibrary.org/obo/UBERON_0001824 mucosa of larynx http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa The mucous lining of the larynx, which is composed of squamous epithelium in the upper larynx and ciliated columnar epithelium in the lower larynx. http://purl.obolibrary.org/obo/UBERON_0001873 caudate nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Subcortical nucleus of telecephalic origin consisting of an elongated gray mass lying lateral to and bordering the lateral ventricle. It is divided into a head, body and tail in some species. http://purl.obolibrary.org/obo/UBERON_0001874 putamen http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Subcortical nucleus of telencephalic , which together with the caudate nucleus, forms the striatum. The putamen lies lateral to the internal capsule and medial to the external medullary lamina, and is separated from the caudate nucleus by the fibers of the internal capsule for most of its length, except at its anterior portion. http://purl.obolibrary.org/obo/UBERON_0001875 globus pallidus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Subcortical nucleus, functionally part of the basal ganglia, which consists of two segments the external (or lateral) and internal (or medial) separated by the medial medullary lamina in primates. In rodents, The globus pallidus lateral is separated from the medial segment by the fibers of the internal capsule/cerebral peduncle. http://purl.obolibrary.org/obo/UBERON_0001881 island of Calleja http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus One of the seven small groups of granule cells in the polymorph layer of the olfactory tubercle and one large group, the insula magna, which lies along the border between septum, nucleus accumbens and nucleus of the diagonal band. http://purl.obolibrary.org/obo/UBERON_0001882 nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus A region of the brain consisting of a collection of neurons located in the forebrain ventral to the caudate and putamen. (caudoputamen in rodent) and continuous with these structures. There is no distinct boundary between the nucleus accumbens and the caudate/putamen, but in rodents, it can be identified by its lack of traversing fiber bundles in comparison to the dorsal striatum. Its principle neuron is the medium spiny neuron. Together with the neostriatum (caudate nucleus and putamen), the nucleus accumbens forms the striatum. http://purl.obolibrary.org/obo/UBERON_0001883 olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus Region in the ventral telencephalon, prominent in rodents, but present in all mammals, consisting of a laminated cortical part and the cap/hilus region. It is traditionally viewed as part of the olfactory cortex but recognized by some as having a striatal character. According to many authors, the structure of the OT transitions from cortical like to striatal like along the lateral medial axis. (Maryann Martone). http://purl.obolibrary.org/obo/UBERON_0001884 phrenic nerve http://purl.obolibrary.org/obo/UBERON_0003443 thoracic cavity nerve A nerve that arises from the caudal cervical nerves and is primarily the motor nerve of the diaphragm but also sends sensory fibers to the pericardium. http://purl.obolibrary.org/obo/UBERON_0001890 forebrain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The most anterior region of the brain including both the telencephalon and diencephalon. http://purl.obolibrary.org/obo/UBERON_0001891 midbrain http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles)[GO]. http://purl.obolibrary.org/obo/UBERON_0001892 rhombomere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A segment of the developing hindbrain[ZFA]. In the vertebrate embryo, a rhombomere is a transiently divided segment of the developing neural tube, within the hindbrain region (a neuromere) in the area that will eventually become the rhombencephalon. The rhombomeres appear as a series of slightly constricted swellings in the neural tube, caudal to the cephalic flexure.[WP]. http://purl.obolibrary.org/obo/UBERON_0001895 metencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain Rostral segment of the hindbrain that has as its parts the pons (where present) and the cerebellum[WP,modified]. http://purl.obolibrary.org/obo/UBERON_0001896 medulla oblongata http://purl.obolibrary.org/obo/UBERON_0000064 organ part Organ component of neuraxis that has as its parts the medullary reticular formation, inferior olivary complex and cochlear nuclear complex, among other structures[FMA]. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate[GO]. http://purl.obolibrary.org/obo/UBERON_0001897 dorsal plus ventral thalamus http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Subcortical brain region consisting of paired gray matter bodies in the dorsal diencephalon and forming part of the lateral wall of the third ventricle of the brain. The thalamus represents the major portion of the diencephalon and is commonly divided into cellular aggregates known as nuclear groups.(MeSH). The dorsal topographic division of the interbrain. The macrodissected adult human thalamus was clearly illustrated by Vesalius in 1543 and the term as defined here was introduced by His in 1893. It includes the traditional epithalamus, dorsal thalamus, and ventral thalamus of Herrick (1910, pp. 494, 498). Also see Kuhlenbeck (1927, Ch. 9) and Jones (1985, p. 87). http://purl.obolibrary.org/obo/UBERON_0001898 hypothalamus http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0001899 epithalamus http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Most dorsal part of the thalamus, comprising the pineal gland and habenular nuclei in most vertebrates. In a few vertebrates, it also includes the parietal eye. (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed, 2005, pg. 345-346. http://purl.obolibrary.org/obo/UBERON_0001901 epithelium of trachea http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium The epithelial lining of the trachea which contains numerous ciliated cells. http://purl.obolibrary.org/obo/UBERON_0001915 endothelium of capillary http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of a capillary [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001916 endothelium of arteriole http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of an arteriole [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium An endothelium that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001918 endothelium of venule http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium An endothelium that is part of a venule [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein http://purl.obolibrary.org/obo/UBERON_0004701 venous system endothelium An endothelium that is part of a vein [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001932 arcuate nucleus of hypothalamus http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus The arcuate nucleus (or infundibular nucleus) is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence. The arcuate nucleus includes several important populations of neurons, including: Neuroendocrine neurons, Centrally-projecting neurons and Others. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0001943 midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Ventral part of the midbrain, separated from the hindbrain by the isthmus[ISBN:0471888893]. Subdivision of the midbrain lying anterior to the tectum and posterior to the substantia nigra and cerebral peduncle[FMA] The part of the midbrain extending from the substantia nigra to the cerebral aqueduct in a horizontal section of the midbrain. It forms the floor of the midbrain that surrounds the cerebral aqueduct[WP]. http://purl.obolibrary.org/obo/UBERON_0001948 regional part of spinal cord http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system A multi-tissue structure that is part of a spinal cord. http://purl.obolibrary.org/obo/UBERON_0001950 neocortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain An area of cerebral cortex defined on the basis of cytoarchitecture that have six layers. Starting from the cortical surface the layers are: molecular layer (I), external granular layer (II), external pyramidal layer (III), internal granular layer (IV), internal pyramidal layer (V), and multiform layer (VI). Neocortex is most prominent in the frontal lobe, the parietal lobe, the temporal lobe and the occipital lobe, less so in the cingulate gyrus, the parahippocampal gyrus and the insula. It is composed of two subdivisions: true isocortex and proisocortex (Carpenter-83)(NN). http://purl.obolibrary.org/obo/UBERON_0001956 cartilage of bronchus http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage The hyaline cartilaginous structures that support the bronchi, present as irregular rings in the larger bronchi (and not as regular as in the trachea), and as small plates and islands in the smaller bronchi; as the branching continues through the bronchial tree, the amount of hyaline cartilage in the walls decreases until it is absent in the smallest bronchioles[MP]. http://purl.obolibrary.org/obo/UBERON_0001957 submucosa of bronchus http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001969 blood plasma http://purl.obolibrary.org/obo/UBERON_0000179 haemolymphatic fluid The liquid component of blood, in which erythrocytes are suspended. http://purl.obolibrary.org/obo/UBERON_0001972 submucosa of esophagus http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract A submucosa that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001974 lamina propria of esophagus http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001975 serosa of esophagus http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane A serous membrane that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0001976 epithelium of esophagus http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium The epithelial layer that lines the luminal space of the esophagus. http://purl.obolibrary.org/obo/UBERON_0001979 venule http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel One of the minute vessels that collect deoxygenated blood from the capillary plexuses returns it to the veins. http://purl.obolibrary.org/obo/UBERON_0001980 arteriole http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel The smallest division of the artery located between the muscular arteries and the capillaries[GO]. http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel through which blood circulates in the body. http://purl.obolibrary.org/obo/UBERON_0001985 corneal endothelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium A monolayer of specialized, flattened, mitochondria-rich cells that lines the posterior surface of the cornea and faces the anterior chamber of the eye[WP]. http://purl.obolibrary.org/obo/UBERON_0001986 endothelium http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A layer of epithelium that lines the heart, blood vessels (endothelium, vascular), lymph vessels (endothelium, lymphatic), and the serous cavities of the body[MESH]. Simple squamous epithelium which lines blood and lymphatic vessels and the heart[FMA]. http://purl.obolibrary.org/obo/UBERON_0001994 hyaline cartilage tissue http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue Cartilage tissue primarily composed of type II collagen (thin fibrils) and a glassy appearance. http://purl.obolibrary.org/obo/UBERON_0002020 gray matter http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A nervous system structure composed primarily of nerve cell bodies (somas). May also include dendrites and the initial unmyelinated portion of axons. http://purl.obolibrary.org/obo/UBERON_0002028 hindbrain http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The most posterior of the three principal regions of the brain. In mammals and birds the hindbrain is divided into a rostral metencephalon and a caudal myelencephalon. In zebrafish, with the exception of the cerebellum, the ventral remainder of the metencephalon can be separated only arbitrarily from the more caudal myelencephalic portion of the medulla oblongata (From: Neuroanatomy of the Zebrafish Brain)[ZFA]. Organ component of neuraxis that has as its parts the pons, cerebellum and medulla oblongata[FMA]. http://purl.obolibrary.org/obo/UBERON_0002031 epithelium of bronchus http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium An epithelium that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue Muscle tissue that contains fibers that are divided by transverse bands into striations. http://purl.obolibrary.org/obo/UBERON_0002040 bronchial artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A systemic artery that supplies the lung with with oxygenated blood. http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus The pontine raphe nucleus is one of the raphe nuclei. It is located in the pontine tegmentum. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster An interconnected tubular multi-tissue structure contains fluid that is actively transported around the organism[ZFA]. Examples: vasculature of lung, vasculature of face. http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anatomical structure that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0002057 phrenic artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that supplies the diaphragm. http://purl.obolibrary.org/obo/UBERON_0002061 truncus arteriosus http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel The truncus arteriosus and bulbus cordis are divided by the aorticopulmonary septum. The truncus arteriosus gives rise to the ascending aorta and the pulmonary trunk. The bulbus cordis gives rise to the smooth parts (outflow tract) of the left and right ventricles. http://purl.obolibrary.org/obo/UBERON_0002062 endocardial cushion http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves[GO]. Swellings of tissue present between the endocardial and myocardial cell layers that will give rise to the interstitial cells of the cardiac valves[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002063 sinus venosus http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber The sinus venosus is a large cardiac chamber at the inflow tract that receives venous blood from systemic circulation. precedes the atrium on the venous side of the chordate heart. http://purl.obolibrary.org/obo/UBERON_0002072 hypodermis http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. http://purl.obolibrary.org/obo/UBERON_0002075 viscus http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that is located within the body cavity (or in its extension, in the scrotum); it consists of organ parts that are embryologically derived from endoderm, splanchnic mesoderm or intermediate mesoderm; together with other organs, the viscus constitutes the respiratory, gastrointestinal, urinary, reproductive and immune systems, or is the central organ of the cardiovascular system. Examples: heart, lung, esophagus, kidney, ovary, spleen. http://purl.obolibrary.org/obo/UBERON_0002078 right cardiac atrium http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber A cardiac atrium that is in the right side of the heart. It receives deoxygenated blood. In mammals, this comes from the superior and inferior vena cava and the coronary sinus, and pumps it into the right ventricle through the tricuspid valve. http://purl.obolibrary.org/obo/UBERON_0002079 left cardiac atrium http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber A cardiac atrium that is in the left side of the heart. It receives oxygenated blood from the pulmonary veins, In mammals this is pumped into the left ventricle, via the Mitral valve. http://purl.obolibrary.org/obo/UBERON_0002080 heart right ventricle http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber A cardiac ventricle that is in the right side of the heart. http://purl.obolibrary.org/obo/UBERON_0002081 cardiac atrium http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber Cardiac chamber in which blood enters the heart. http://purl.obolibrary.org/obo/UBERON_0002082 cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber Cardiac chamber through which blood leaves the heart. http://purl.obolibrary.org/obo/UBERON_0002084 heart left ventricle http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber A cardiac ventricle that is in the left side of the heart. http://purl.obolibrary.org/obo/UBERON_0002085 interatrial septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum A cardiac septum that divides the left and right atria of the heart. http://purl.obolibrary.org/obo/UBERON_0002090 postcranial axial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The postcranial subdivision of skeleton structural components forming the long axis of the vertebrate body; in Danio, consisting of the notochord, vertebrae, ribs, supraneurals, intermuscular bones, and unpaired median fins; in human consists of the bones of the vertebral column, the thoracic cage and the pelvis[ZFA+FMA]. http://purl.obolibrary.org/obo/UBERON_0002091 appendicular skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which which consists of all the skeletal elements in in the pectoral and pelvic appendage complexes[cjm]. http://purl.obolibrary.org/obo/UBERON_0002092 brain dura mater http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx The fibrous membrane forming the outer of the three coverings that surrounds the brain within the cranial cavity; consists of two layers including the periosteal layer and the meningeal layer. http://purl.obolibrary.org/obo/UBERON_0002093 spinal dura mater http://purl.obolibrary.org/obo/UBERON_0002363 dura mater A dura mater that is part of a spinal cord [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002094 interventricular septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum Cardiac septum which separates the right ventricle from the left ventricle.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002097 skin of body http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The organ covering the body that consists of the dermis and epidermis. http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum http://purl.obolibrary.org/obo/UBERON_0003037 septum The thin membranous structure between parts of the heart, including the atria, ventricles, and outflow tract. http://purl.obolibrary.org/obo/UBERON_0002100 trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis Organism subdivision which is the part of the body posterior to the cervical region (or head, when cervical region not present) and anterior to the caudal region. Includes the sacrum when present. http://purl.obolibrary.org/obo/UBERON_0002104 visual system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system subserving the sense of vision. http://purl.obolibrary.org/obo/UBERON_0002105 vestibulo-auditory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system Sensory system responsible for the perception of spatial orientation and auditory stimuli. http://purl.obolibrary.org/obo/UBERON_0002111 artery smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle A portion of smooth muscle tissue that is part of an artery [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002112 smooth muscle of esophagus http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002118 right ovary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An ovary that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002119 left ovary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An ovary that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002128 superior olivary complex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain A collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system. http://purl.obolibrary.org/obo/UBERON_0002129 cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain The superficial gray matter of the cerebellum. It consists of three main layers, the molecular layer, the Purkinje cell layer and the granule cell layer. http://purl.obolibrary.org/obo/UBERON_0002139 subcommissural organ http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ The subcommissural organ is a circumventricular organ consisting of ependymal and hypendymal cells which secrete SCO-spondin[WP,partially vetted]. http://purl.obolibrary.org/obo/UBERON_0002148 locus ceruleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic[GO]. Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis[GAID]. http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata Nucleus containing parasympathetic neurons giving rise to the parasympathetic division of the facial nerve, innervating the salivary glands (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 703). http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium http://purl.obolibrary.org/obo/UBERON_0002165 endocardium Endocardium that is part of the atrium. http://purl.obolibrary.org/obo/UBERON_0002167 right lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the right upper lobe, middle lobe and right lower lobe.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002168 left lung http://purl.obolibrary.org/obo/UBERON_0002048 lung Lung which consists of the left upper lobe and left lower lobe.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002190 subcutaneous adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue A portion of adipose tissue that is part of the hypodermis, beneath the dermis. http://purl.obolibrary.org/obo/UBERON_0002193 hemolymphoid system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Anatomical cluster consisting of the hematopoietic system and the lymphoid system, or its analogs. http://purl.obolibrary.org/obo/UBERON_0002196 adenohypophysis http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The glandular, anterior lobe of the pituitary gland. The anterior pituitary regulates several physiological processes including stress, growth, and reproduction[WP]. The anterior lobe of the hypophysis (pituitary gland). This lobe contains cells that produce prolactin, growth hormone, thyroid-stimulating hormone, follicle-stimulating hormone and proopiomelanocortin[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002197 median eminence of neurohypophysis http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ Elevation on the ventral surface of the brain located at the zone of attachment between the hypothalamic floor and the hypophysis (Butler and Hodos, Comparative Vertebrate Neuroanatomy, 2nd ed., 2005, pg. 446). http://purl.obolibrary.org/obo/UBERON_0002199 integument http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision The dermis, epidermis and hypodermis. http://purl.obolibrary.org/obo/UBERON_0002200 vasculature of head http://purl.obolibrary.org/obo/UBERON_0002049 vasculature Vasculature that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002201 vasculature of trunk http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002202 submucosa of trachea http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ Vasculature that is part of the eye region. http://purl.obolibrary.org/obo/UBERON_0002209 fibrous joint http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint Nonsynovial joint in which the articulating bones or cartilages are connected by ligaments. Examples: sagittal suture, inferior tibiofibular syndesmosis, gomphosis.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint Nonsynovial joint in which the articulating bones or cartilages are connected by cartilage. Examples: Spheno-occipital synchondrosis, first sternocostal joint, pubic symphysis.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002215 synchondrosis http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint Cartilaginous joint in which the articulating bones or cartilages are connected by hyaline cartilage. Examples: spheno-occipital synchondrosis, first sternocostal joint.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002216 symphysis http://purl.obolibrary.org/obo/UBERON_0002213 cartilaginous joint Cartilaginous joint in which the articulating bones or cartilages are connected by fibrocartilage. Examples: pubic symphysis, intervertebral symphysis, manubriosternal joint.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by an articular capsule which encloses a synovial membrane and a synovial cavity. Examples: Temporomandibular joint, knee joint.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002219 subfornical organ http://purl.obolibrary.org/obo/UBERON_0010135 sensory circumventricular organ Group of neurons situated on the ventral surface of the fornix at the level of the foramen of Monro in the third ventricle (adapted from Wikipedia via NIF). http://purl.obolibrary.org/obo/UBERON_0002224 thoracic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the coelemic cavity lumen that is enclosed by the walls of the thorax. http://purl.obolibrary.org/obo/UBERON_0002241 chondrocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Endoskeletal elements that encase the brain, nose, inner ear[cjm]. that part of the neurocranium formed by endochondral ossification and comprising the bones of the base of the skull[TFD]. http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column The ventral grey column of the spinal cord[MP]. The neurons of the ventral region of the mature spinal cord participate in motor output[GO]. http://purl.obolibrary.org/obo/UBERON_0002263 lentiform nucleus http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus The lentiform nucleus or lenticular nucleus comprises the putamen and the globus pallidus within the basal ganglia. It is a large, cone-shaped mass of gray matter just lateral to the internal capsule. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002275 reticular formation http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A composite substructure of the brainstem that consists of the midbrain reticular formation, the pontine reticular formation and the medullary reticular formation ( Carpenter-1983 ). http://purl.obolibrary.org/obo/UBERON_0002288 choroid plexus of third ventricle http://purl.obolibrary.org/obo/UBERON_0001886 choroid plexus Part of choroid plexus contained in the third ventricle. http://purl.obolibrary.org/obo/UBERON_0002290 choroid plexus of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0006694 cerebellum vasculature Choroid plexus of the fourth ventricle. http://purl.obolibrary.org/obo/UBERON_0002291 central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. http://purl.obolibrary.org/obo/UBERON_0002301 layer of neocortex http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex One of the layers of the neocortex. These layers are defined by distinctive populations of cells based on somata size, shape, or density, that are aligned into sheets. http://purl.obolibrary.org/obo/UBERON_0002302 myocardium of atrium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium The atrial part of middle layer of the heart, comprised of involuntary muscle. http://purl.obolibrary.org/obo/UBERON_0002307 choroid plexus of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0001886 choroid plexus Part of choroid plexus contained in the lateral ventricle. http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A neural nucleus that is part of the brain. http://purl.obolibrary.org/obo/UBERON_0002314 midbrain tectum http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Dorsal part of the midbrain, consisting of the superior and inferior colliculi and the pretectal nuclei (MM). http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002020 gray matter The ridge-shaped grey matter of the spinal cord that extends longitudunally through the center of each half of the spinal cord, and are largely or entirely composed of nerve cell bodies and their dendrites and some supportive tissue. http://purl.obolibrary.org/obo/UBERON_0002316 white matter http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster Neural tissue consisting of myelinated axons connecting grey matter areas of the central nervous system. http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0002316 white matter The regions of the spinal cord that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. http://purl.obolibrary.org/obo/UBERON_0002323 coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity within the body of all animals higher than the coelenterates and certain primitive worms, formed by the splitting of the embryonic mesoderm into two layers. In mammals it forms the peritoneal, pleural, and pericardial cavities. http://purl.obolibrary.org/obo/UBERON_0002324 muscle of back http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element Any muscle organ that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002328 notochord http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A flexible rod-shaped body found in embryos of all chordates. It is composed of cells derived from the mesoderm and defines the primitive axis of the embryo. In some chordates, it persists throughout life as the main axial support of the body, while in most vertebrates it becomes the nucleus pulposus of the intervertebral disc. The notochord is found ventral to the neural tube. http://purl.obolibrary.org/obo/UBERON_0002329 somite http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle Somites are spheres of epithelial cells that form sequentially along the anterior-posterior axis of the embryo through mesenchymal to epithelial transition of the presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0002333 pulmonary trunk http://purl.obolibrary.org/obo/UBERON_0001637 artery An arterial trunk which is continuous with the heart and branches into the pulmonary arteries. http://purl.obolibrary.org/obo/UBERON_0002338 lamina propria of bronchus http://purl.obolibrary.org/obo/UBERON_0000031 lamina propria of trachea A lamina propria that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002342 neural crest http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. http://purl.obolibrary.org/obo/UBERON_0002343 abdomen musculature http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk Set of all muscles in abdomen. http://purl.obolibrary.org/obo/UBERON_0002345 descending thoracic aorta http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The part of the aorta that extends from the arch of the aorta to the diaphragm, and from which arises numerous branches that supply oxygenated blood to the chest cage and the organs within the chest. http://purl.obolibrary.org/obo/UBERON_0002346 neurectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Embryonic ectoderm that gives rise to nervous tissue. http://purl.obolibrary.org/obo/UBERON_0002350 conducting system of heart http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat[GO]. http://purl.obolibrary.org/obo/UBERON_0002352 atrioventricular node http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart An area of conducting tissue between the atria and the ventricles of the heart that conducts the normal electrical impulse from the atria to the ventricles. http://purl.obolibrary.org/obo/UBERON_0002354 cardiac Purkinje fiber http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The cardiac Purkinje fiber is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. http://purl.obolibrary.org/obo/UBERON_0002357 serous pericardium http://purl.obolibrary.org/obo/UBERON_0000042 serous membrane Serous membrane which is divided into parietal and visceral serous pericardium. http://purl.obolibrary.org/obo/UBERON_0002359 fibrous pericardium http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ Membrane organ which is attached to the pericardial sac proper and the central tendon of diaphragm and is continuous with the pretracheal fascia.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002360 meninx http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Membrane organ that surrounds the brain and the spinal cord. http://purl.obolibrary.org/obo/UBERON_0002362 arachnoid mater http://purl.obolibrary.org/obo/UBERON_0000391 leptomeninx A think avascular meningeal layer, between the pia mater and the dural mater. It is separated from the pia mater by the subarachnoid space. http://purl.obolibrary.org/obo/UBERON_0002363 dura mater http://purl.obolibrary.org/obo/UBERON_0002360 meninx Thick, fibrous meningeal covering surrounding the brain and spinal cord. It is the outermost of the three meningeal coverings. It consists of two layers: the periosteal dura linking the inner surface of the skull and the meningeal dura that lies above the arachnoid dural membrane. The meningeal layer draws away from the periosteal layer and certain locations to form the dural reflections. http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that secretes products (excluding hormones and other chemical messengers) into ducts (duct glands) which lead directly into the external environment[WP]. Typical exocrine glands include sweat glands, salivary glands, mammary glands, stomach, liver, pancreas. http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle Any skeletal muscle that is part of the head region. http://purl.obolibrary.org/obo/UBERON_0002377 muscle of neck http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle Any muscle that is part of the cervical (neck) region. http://purl.obolibrary.org/obo/UBERON_0002378 muscle of abdomen http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element Muscle (organ) which is a part of the abdomen. Examples: external oblique, rectus abdominis. http://purl.obolibrary.org/obo/UBERON_0002400 parietal pleura http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The outer serous membrane of the pulmonary pleural. http://purl.obolibrary.org/obo/UBERON_0002401 visceral pleura http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane The inner serous membrane of the pulmonary pleural. The visceral pleura lines the lungs. http://purl.obolibrary.org/obo/UBERON_0002402 pleural cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity The fluid-filled cavity that lies between the visceral and parietal pleurae. http://purl.obolibrary.org/obo/UBERON_0002406 pericardial sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A double-walled sac containing the heart and the roots of the great vessels. http://purl.obolibrary.org/obo/UBERON_0002408 parietal serous pericardium http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane Parietal serous membrane which is part of the pericardium and forms the outer layer of the pericardial sac. http://purl.obolibrary.org/obo/UBERON_0002409 pericardial fluid http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid Transudate contained in the pericardial cavity.[FMA]. http://purl.obolibrary.org/obo/UBERON_0002417 abdominal segment of trunk http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis The abdominal segment of the torso. http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue that is avascular, rich in glycosaminoglycans (GAGs) and typically includes chondrocytes within isolated lacunae. Cartilage tissue is deposited by chondroblasts. http://purl.obolibrary.org/obo/UBERON_0002419 skin gland http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa A gland that is part of a skin of body [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002422 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0004086 brain ventricle Part of the ventricular system of the brain, forming a single large irregularly shaped cavity located on the midline of the rhombencephalon, between the medulla, pons and the isthmus ventrally and the cerebellum dorsally. It is continuous with the cerebral aqueduct anteriorally and the central canal of the spinal cord posteriorly. It communicates with the subarachnoid space through its lateral and median apertures. http://purl.obolibrary.org/obo/UBERON_0002424 oral epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of the mouth and lines the oral cavity, typically stratified squamous, and may be para-, ortho- or non- keratinized. Primary barrier between oral environment and deeper tissues. http://purl.obolibrary.org/obo/UBERON_0002425 visceral serous pericardium http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane Visceral serous membrane which is continuous with the parietal serous pericardium and is attached to the myocardium[FMA]. http://purl.obolibrary.org/obo/UBERON_0002435 striatum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon A region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.[GO]. http://purl.obolibrary.org/obo/UBERON_0002437 cerebral hemisphere white matter http://purl.obolibrary.org/obo/UBERON_0011299 white matter of telencephalon White matter that is part of a cerebral hemisphere. http://purl.obolibrary.org/obo/UBERON_0002443 choroidal blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a choroid [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002457 intersomitic artery http://purl.obolibrary.org/obo/UBERON_0014907 intersomitic vessel The small branching sprouts of the dorsal aorta that grow across the medial surface of the somite, turn right angles to grow over that surface and then fuse with other sprouts and form the vertebral arteries adjacent to the neural tube; the intersomitic arteries supply the body wall and persist in the adult as the posterior intercostal, subcostal and the lumbar arteries. http://purl.obolibrary.org/obo/UBERON_0002458 spinal artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery Arteries that supply the spinal cord. http://purl.obolibrary.org/obo/UBERON_0002469 esophagus mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucosa that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002476 lateral globus pallidus http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter The more lateral of the two segments of the globus pallidus, abutting the putamen. http://purl.obolibrary.org/obo/UBERON_0002477 medial globus pallidus http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter The more medial segment of the globus pallidus. http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue Skeletal tissue with a collagen-rich extracellular matrix vascularized, mineralized with hydroxyapatite and typically including osteocytes located in lacunae that communicate with one another by cell processes (in canaliculi). Bone is deposited by osteoblasts. http://purl.obolibrary.org/obo/UBERON_0002506 iris epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002513 endochondral bone http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element Replacement bone that forms within cartilage. http://purl.obolibrary.org/obo/UBERON_0002514 intramembranous bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Bone tissue forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue composed of elastic fibers. http://purl.obolibrary.org/obo/UBERON_0002522 tunica media http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer The middle layer of an artery or vein. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0002523 tunica intima http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The innermost layer of a blood vessel which is a lining of endothelial cells facing the lumen[Kardong]. http://purl.obolibrary.org/obo/UBERON_0002530 gland http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ that functions as a secretory or excretory organ. http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure In amniote animal embryology, the epiblast is a tissue type derived either from the inner cell mass in mammals or the blastodisc in birds and reptiles. It lies above the hypoblast. In mammalian embryogenesis, the columnar cells of the epiblast are adjacent to the trophoblast, while the cuboidal cells of the hypoblast are closer to the blastocoele. The epiblast, whilst referred to as the primary ectoderm, differentiates to form all three layers of the trilaminar germ disc in a process called gastrulation[WP]. The outer of the two layers of the blastoderm that form during gastrulation, corresponding to primitive ectoderm during gastrulation and to the definitive ectoderm after gastrulation[ZFA]. http://purl.obolibrary.org/obo/UBERON_0002536 arthropod sensillum http://purl.obolibrary.org/obo/UBERON_0000020 sense organ Sense organ embedded in the integument and consisting of one or a cluster of sensory neurons and associated sensory structures, support cells and glial cells forming a single organised unit with a largely bona-fide boundary.[FBbt]. http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest One of a series of paired bulges that develop along the lateral walls of the foregut. The pharyngeal arches have developmental contributions from endoderm, mesoderm, and neural crest cells and are separated by anterior lateral endoderm out-pockets known as pharyngeal pouches. http://purl.obolibrary.org/obo/UBERON_0002546 cranial placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that develops in the head into a part of the sensory nervous system. With a few exceptions (lens, adenohypophyseal), cranial placodes are neurogenic. http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Anatomical space which contains portions of one or more body substances and is bounded by the internal surface of one maximally connected anatomical structure. Examples: cranial cavity, pharyngeal recess space, nasal cavity, tooth socket, cavity of serous sac, lumen of stomach, lumen of artery, fornix of vagina. http://purl.obolibrary.org/obo/UBERON_0002555 intermediate hypothalamic region http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The portion of the hypothalamus located generally internal to the region of the infundibulum. http://purl.obolibrary.org/obo/UBERON_0002561 lumen of central nervous system http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity The cavity that is enclosed by the central nervous system. In vertebrates this is the cavity that includes as parts ventricular cavities and the central canal of the spinal cord that develops from the lumen of the neura tube. http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain http://purl.obolibrary.org/obo/UBERON_0000073 regional part of nervous system Anatomical divisons of the brain according to one or more criteria, e.g. cytoarchitectural, gross anatomy. Parts may be contiguous in 3D or not, e.g., basal ganglia. http://purl.obolibrary.org/obo/UBERON_0002663 septal nuclear complex http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis Collection of nerve cells in the medial forebrain lying generally in front of the anterior commissure (Maryann Martone). http://purl.obolibrary.org/obo/UBERON_0002726 cervical spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment A spinal cord segment that adjacent_to a cervical region. http://purl.obolibrary.org/obo/UBERON_0002743 basal forebrain http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A region of the brain consisting of ventral and rostral subcortical regions of the telencephalon, including among others, the basal ganglia, septal nuclei, amygdala, ventral pallidum, substantia innominata, and basal nucleus of Meynert. http://purl.obolibrary.org/obo/UBERON_0002749 regional part of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain A regional part of brain that is part of a cerebellar cortex [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0002812 left cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0001869 cerebral hemisphere A cerebral hemisphere that is in the left side of a brain. http://purl.obolibrary.org/obo/UBERON_0002813 right cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0001869 cerebral hemisphere A cerebral hemisphere that is in the right side of a brain. http://purl.obolibrary.org/obo/UBERON_0002871 hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata Nucleus forming a longitudinal cell column in the medulla, close beneath the floor of the 4th ventricle, containing motor neurons that innervate the muscles of the tongue (Brodal, Neurological Anatomy, 3rd ed., 1981, pg 453). http://purl.obolibrary.org/obo/UBERON_0002894 olfactory cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Aggregate brain region defined as those areas of cerebral cortex receiving direct synaptic input from the olfactory bulb (Price, 1973). It usually includes the piriform cortex and sometimes other areas. http://purl.obolibrary.org/obo/UBERON_0002925 trigeminal nucleus http://purl.obolibrary.org/obo/UBERON_0000126 cranial nerve nucleus A nucleus of brain that is part of a trigeminal nuclear complex. http://purl.obolibrary.org/obo/UBERON_0002926 gustatory epithelium http://purl.obolibrary.org/obo/UBERON_0006934 sensory epithelium A sensory epithelium that is part of a gustatory system. http://purl.obolibrary.org/obo/UBERON_0002956 granular layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/UBERON_0002974 molecular layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/UBERON_0002979 Purkinje cell layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/UBERON_0003023 pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0000064 organ part Dorsal portion of the pons, containing cranial nervee nuclei, ascending and descending tracts and reticular nuclei. It is continuous with the reticular formation of the medulla (Carpenter, A Core Text of Neuroanatomy, 3rd ed, 1985, pg 133). http://purl.obolibrary.org/obo/UBERON_0003037 septum http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A wall, dividing a cavity or structure into smaller ones[WP]. http://purl.obolibrary.org/obo/UBERON_0003038 thoracic spinal cord http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment The thoracic nerves are the spinal nerves emerging from the thoracic vertebrae. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0003041 trigeminal nerve fibers http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber A nerve fiber that is part of a trigeminal nerve. http://purl.obolibrary.org/obo/UBERON_0003052 midbrain-hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The part of the brain that is the morphological boundary between the midbrain and hindbrain and that is the location of an organizing center which patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/UBERON_0003055 periderm http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure The outermost layer (or layers, depending on the species) of embryonic skin, essential for the development of the epidermis and establishment of the barrier functions. The periderm derives from the outer layer of the ectoderm. http://purl.obolibrary.org/obo/UBERON_0003056 pre-chordal neural plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The portion of neural plate anterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003057 chordal neural plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The portion of neural plate posterior to the mid-hindbrain junction. http://purl.obolibrary.org/obo/UBERON_0003059 presomitic mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Unsegmented field of paraxial mesoderm present posterior to the most recently formed somite pair, from which somites will form. http://purl.obolibrary.org/obo/UBERON_0003061 blood island http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system. They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma. The lumen of the blood vessels thus formed is probably intracellular. The flattened cells at the periphery form the endothelium. The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells. In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel. Such a mass is known as a blood island and hemoglobin gradually accumulates within it. Later the cells on the surface round up, giving the mass a mulberry-like appearance. Then the red blood cells break loose and are carried away in the plasma. Such free blood cells continue to divide. Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta[WP, unvetted]. http://purl.obolibrary.org/obo/UBERON_0003063 prechordal plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A horseshoe-shaped thickening of the endoderm at the cranial (rostral) end of the primitive streak formed by the involution of Spemann's organizer cells which, together with the notochord, induces the formation of the neural plate from the overlying ectodermal cells and contributes mesodermal type cells to the surrounding tissue. http://purl.obolibrary.org/obo/UBERON_0003064 intermediate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. http://purl.obolibrary.org/obo/UBERON_0003066 pharyngeal arch 2 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The second pharyngeal arch will form the hyoid apparatus. The cranial neural crest cells that populate the second pharyngeal arch emerge primarily from rhombomere 4 and will form skeletal elements. http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode Lateral neurogenic placodes positioned dorsal of the epibranchial placodes. http://purl.obolibrary.org/obo/UBERON_0003068 axial mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. http://purl.obolibrary.org/obo/UBERON_0003070 trigeminal placode complex http://purl.obolibrary.org/obo/UBERON_0003067 dorsolateral placode A neurogenic placode that arises at the level of the midbrain-hindbrain boundary and develops into a trigeminal ganglion. http://purl.obolibrary.org/obo/UBERON_0003072 optic cup http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Multi-tissue structure that is comprised of neural and non-neural epithelial layers which will form the retina and retinal pigmented epithelium of the mature eye[ZFA]. double walled structured formed by expansion and invagination of the distal end of the optic vesicle that develops into the pigmented and sensory layers of the retina while the mouth of the optic cup eventually forms the pupil of the eye[MP]. http://purl.obolibrary.org/obo/UBERON_0003073 lens placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode A thickened portion of ectoderm which serves as the precursor to the lens. SOX2 and Pou2f1 are involved in its development[WP]. http://purl.obolibrary.org/obo/UBERON_0003075 neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A region of embryonic ectodermal cells that lie directly above the notochord. During neurulation, they change shape and produce an infolding of the neural plate (the neural fold) that then seals to form the neural tube[XAO]. The earliest recognizable dorsal ectodermal primordium of the central nervous system present near the end of gastrulation before infolding to form the neural keel; consists of a thickened pseudostratified epithelium[ZFA]. http://purl.obolibrary.org/obo/UBERON_0003077 paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube[GO]. http://purl.obolibrary.org/obo/UBERON_0003078 epibranchial placode http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode Focal thickenings of the embryonic ectoderm that form immediately dorsal and caudal of the clefts between the pharyngeal arches and that produce the neuroblasts that migrate and condense to form the distal cranial ganglia. http://purl.obolibrary.org/obo/UBERON_0003079 floor plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The specialized glial structure (non-neuronal cells) situated at the ventral midline of the embryonic neural tube; this structure spans the anteroposterior axis from the midbrain to the tail regions, separating the left and right basal plates of the developing neural tube, and serves as an organizer to ventralize tissues in the embryo as well as to guide neuronal positioning and differentiation along the dorsoventral axis of the neural tube. http://purl.obolibrary.org/obo/UBERON_0003081 lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Portion of the middle of the three primary germ layers of the embryo that resides on the periphery of the embryo, is continuous with the extra-embryonic mesoderm, splits into two layers enclosing the intra-embryonic coelom, and gives rise to body wall structures[MP]. http://purl.obolibrary.org/obo/UBERON_0003082 myotome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become muscle cells. http://purl.obolibrary.org/obo/UBERON_0003083 trunk neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Trunk portion of the neural crest. The trunk neural crest lies between the vagal and sacral neural crest and gives rise to two groups of cells. One group migrates dorsolateral and populates the skin, forming pigment cells and the other migrates ventrolateral through the anterior sclerotome to become the epinephrine-producing cells of the adrenal gland and the neurons of the sympathetic nervous system. Some cells remain in the sclerotome to form the dorsal root ganglia [Wikipedia]. http://purl.obolibrary.org/obo/UBERON_0003084 heart primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Bilateral groups of cells consisting of three rows: one row of endocardial precursors medially and two rows of myocardical precursors laterally. The two populations fuse at the midline to form the heart rudiment or cone. http://purl.obolibrary.org/obo/UBERON_0003089 sclerotome http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Ventral somitic compartment that is a precursor of the axial skeleton[XAO]. Sclerotomes eventually differentiate into the vertebrae and most of the skull. The caudal (posterior) half of one sclerotome fuses with the rostral (anterior) half of the adjacent one to form each vertebra. From their initial location within the somite, the sclerotome cells migrate medially towards the notochord. These cells meet the sclerotome cells from the other side to form the vertebral body. From this vertebral body, sclerotome cells move dorsally and surround the developing spinal cord, forming the vertebral arch[WP]. http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. http://purl.obolibrary.org/obo/UBERON_0003100 female organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism Gonochoristic organism that can produce female gametes. http://purl.obolibrary.org/obo/UBERON_0003102 surface structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that overlaps the outer epithelial layer and is adjacent to the space surrounding the organism. http://purl.obolibrary.org/obo/UBERON_0003103 compound organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Anatomical structure that has as its parts two or more multi-tissue structures of at least two different types and which through specific morphogenetic processes forms a single distinct structural unit demarcated by bona fide boundaries from other distinct anatomical structures of different types. http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue composed of mesenchymal cells (motile cells that develop from epthelia via an epithelial to mesenchymal transition) and surrounding extracellular material. Mesenchyme has different embryological origins in different metazoan taxa - in many invertebrates it derives in whole or part from ectoderm. In vertebrates it derives largely from mesoderm, and sometimes the terms are used interchangeably, e.g. lateral plate mesoderm/mesenchyme. http://purl.obolibrary.org/obo/UBERON_0003113 dermatocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Subdivision of skeleton that includes all dermal bones in the cranial skeleton[ZFA,modified]. http://purl.obolibrary.org/obo/UBERON_0003114 pharyngeal arch 3 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The third branchial arch contributes to the development of the hyoid bone, stylopharyngeus muscle, inferior parathyroid gland, and thymus. http://purl.obolibrary.org/obo/UBERON_0003115 pharyngeal arch 4 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch Contributes to development of the cartilage of the larynx, laryngeal, pharyngeal, and soft palate muscles, superior parathyroid gland, and C-cells of the thymus. http://purl.obolibrary.org/obo/UBERON_0003117 pharyngeal arch 6 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The 6th pharyngeal arch. contributes to the development of the sternocleidomastoid and trapezius muscles. http://purl.obolibrary.org/obo/UBERON_0003118 pharyngeal arch artery 1 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the first pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003119 pharyngeal arch artery 2 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the second pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003120 pharyngeal arch artery 3 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the third pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003121 pharyngeal arch artery 4 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the fourth pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003123 pharyngeal arch artery 6 http://purl.obolibrary.org/obo/UBERON_0004363 pharyngeal arch artery The vessels formed within the sixth pair of branchial arches in embryogenesis. http://purl.obolibrary.org/obo/UBERON_0003128 cranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Upper portion of the skull that excludes the mandible (when present in the organism). http://purl.obolibrary.org/obo/UBERON_0003212 gustatory organ http://purl.obolibrary.org/obo/UBERON_0000005 chemosensory organ Any sense organ that functions in (some) detection of chemical stimulus involved in sensory perception of taste (GO:0050912). http://purl.obolibrary.org/obo/UBERON_0003218 ovary septum http://purl.obolibrary.org/obo/UBERON_0003037 septum Septum that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s)[GO]. http://purl.obolibrary.org/obo/UBERON_0003236 epithelium of lower jaw http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium An epithelium that is part of a lower jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003257 yolk sac endoderm http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium The portion of the yolk sac that is derived from endoderm and lines the yolk sac. http://purl.obolibrary.org/obo/UBERON_0003258 endoderm of foregut http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium An endoderm that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003269 skeletal muscle tissue of eye http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a eye [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003278 skeleton of lower jaw http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton A subdivision of the skeleton that corresponds to the lower part of the mouth. The lower jaw skeleton includes the following elements, when present: lower jaw teeth, the mandible and other lower jaw bones, and Meckel's cartilage. http://purl.obolibrary.org/obo/UBERON_0003279 endothelium of trachea http://purl.obolibrary.org/obo/UBERON_0001986 endothelium An endothelium that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0003288 meninx of midbrain http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx A meninx that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003289 meninx of telencephalon http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges A meninx that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003290 meninx of diencephalon http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges A meninx that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003291 meninx of hindbrain http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx A meninx that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003294 gland of foregut http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract A gland that is part of a foregut [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003295 pharyngeal gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland Racemose mucous glands beneath the mucous membrane of the pharynx. http://purl.obolibrary.org/obo/UBERON_0003296 gland of diencephalon http://purl.obolibrary.org/obo/UBERON_0002530 gland Any gland that is part of the diencephalon. Examples: pineal gland, neurohypophysis. http://purl.obolibrary.org/obo/UBERON_0003297 gland of integumental system http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a integumental system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003304 mesoderm blood island http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A blood island that is part of a mesoderm. http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure A floor plate that is part of a neural tube [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003307 floor plate of midbrain http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003308 floor plate of telencephalon http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003309 floor plate of diencephalon http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003310 floor plate of metencephalon http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a metencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003311 floor plate of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A floor plate that is part of a medulla oblongata [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003314 eye mesenchyme http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme Mesenchyme that is part of a developing camera-type eye. http://purl.obolibrary.org/obo/UBERON_0003315 mesenchyme of ovary http://purl.obolibrary.org/obo/UBERON_0003855 gonad mesenchyme Mesenchyme that is part of a developing ovary [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003316 mesenchyme of yolk sac http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme The portion of the yolk sac that is derived from mesoderm and consists of mesenchyme. http://purl.obolibrary.org/obo/UBERON_0003324 mesenchyme of lower jaw http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme Mesenchyme that is part of a developing lower jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003338 ganglion of peripheral nervous system http://purl.obolibrary.org/obo/UBERON_0000045 ganglion A spatially aggregated collection of nerve cell bodies in the PNS, consisting of one or more subpopulations that share cell type, chemical phenotype, and connections. (CUMBO). http://purl.obolibrary.org/obo/UBERON_0003339 ganglion of central nervous system http://purl.obolibrary.org/obo/UBERON_0000045 ganglion A ganglion that is part of a central nervous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003343 mucosa of oral region http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a oral opening [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003350 epithelium of mucosa http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A layer of epithelial cells on the surface of the mucosa. http://purl.obolibrary.org/obo/UBERON_0003351 pharyngeal epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003357 epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium An epithelium that is part of a tongue [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003364 epithelium of right lung http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium An epithelium that is part of a right lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003365 epithelium of left lung http://purl.obolibrary.org/obo/UBERON_0000115 lung epithelium An epithelium that is part of a left lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003372 pectoral appendage bud ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An unilaminar epithelium that surrounds a pectoral appendage bud. http://purl.obolibrary.org/obo/UBERON_0003379 cardiac muscle of right atrium http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of a right atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003380 cardiac muscle of left atrium http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium A portion of cardiac muscle tissue that is part of a left atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003381 cardiac muscle of right ventricle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a right ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003382 cardiac muscle of left ventricle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A portion of cardiac muscle tissue that is part of a left ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003383 cardiac muscle tissue of interventricular septum http://purl.obolibrary.org/obo/UBERON_0004667 interventricular septum muscular part A portion of cardiac muscle tissue that is part of an interventricular septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003384 skeletal muscle tissue of pharynx http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle A portion of skeletal muscle tissue that is part of a pharynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003386 smooth muscle of eye http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Any of the striated muscles that move the eye and include: superior rectus, inferior rectus, medial rectus, lateral rectus, superior oblique, inferior oblique, retractor bulbi. http://purl.obolibrary.org/obo/UBERON_0003387 smooth muscle of trachea http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a trachea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003388 mesothelium of pericardial cavity http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a pericardium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003389 mesothelium of diaphragm http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium A mesothelium that is part of a diaphragm [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003390 mesothelium of pleural cavity http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a pleural cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003406 cartilage of respiratory system http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage element that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A gland that is part of a digestive tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003409 gland of tongue http://purl.obolibrary.org/obo/UBERON_0010047 oral gland Any of the mucous, serous, or mixed glands that empty their secretions onto the surface of the tongue. http://purl.obolibrary.org/obo/UBERON_0003413 pectoral appendage bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme Mesenchyme that is part of a pectoral appendage bud. http://purl.obolibrary.org/obo/UBERON_0003416 mesenchyme of tongue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing tongue [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003426 dermis adipose tissue http://purl.obolibrary.org/obo/UBERON_0003585 dermis connective tissue An adipose tissue that is part of a dermis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003429 abdomen nerve http://purl.obolibrary.org/obo/UBERON_0003825 nerve of abdominal segment A nerve that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003430 neck nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003438 iris nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve Any nerve that innervates the iris. http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of the trunk region of the body (not to be confused with a nerve trunk). http://purl.obolibrary.org/obo/UBERON_0003443 thoracic cavity nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is located in a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003457 head bone http://purl.obolibrary.org/obo/UBERON_0007914 bone of craniocervical region A bone that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003458 neck bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003462 facial bone http://purl.obolibrary.org/obo/UBERON_0003457 head bone A bone that is part of a facial skeleton [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003463 trunk bone http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element A bone that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003469 respiratory system artery http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel An artery that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003471 artery of lower lip http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip The inferior labial artery (inferior labial branch of facial artery) arises near the angle of the mouth; it passes upward and forward beneath the Triangularis and, penetrating the Orbicularis oris, runs in a tortuous course along the edge of the lower lip between this muscle and the mucous membrane. It supplies the labial glands, the mucous membrane, and the muscles of the lower lip; and anastomoses with the artery of the opposite side, and with the mental branch of the inferior alveolar artery. http://purl.obolibrary.org/obo/UBERON_0003472 cerebellar artery http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel An artery that supplies blood to the cerebellum. http://purl.obolibrary.org/obo/UBERON_0003473 thoracic cavity artery http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel An artery that is part of a thoracic cavity[cjm]. http://purl.obolibrary.org/obo/UBERON_0003474 meningeal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery One of the arteries supplying a meninix[Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003476 respiratory system venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003478 vein of lower lip http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip The inferior labial vein is the vein receiving blood from the lower lip. http://purl.obolibrary.org/obo/UBERON_0003479 thoracic cavity vein http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel A vein that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003489 respiratory system capillary endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of capillary that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003494 respiratory system venule http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A venule that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003495 respiratory system arteriole http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel An arteriole that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment blood vessel A blood vessel that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel http://purl.obolibrary.org/obo/UBERON_0005985 coronary vessel A blood vessel that is part of a heart [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003500 corneal blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a cornea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003501 retina blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a retina [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003502 neck blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003505 trachea blood vessel http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A blood vessel that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of the arterial system. Includes artery, arteriole and aorta. http://purl.obolibrary.org/obo/UBERON_0003511 iris blood vessel http://purl.obolibrary.org/obo/UBERON_0003496 head blood vessel A blood vessel that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003512 lung blood vessel http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel A blood vessel that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003519 thoracic cavity blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003526 respiratory system capillary http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel A capillary that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0002020 gray matter A gray matter that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter http://purl.obolibrary.org/obo/UBERON_0002316 white matter The regions of the brain that are largely or entirely composed of myelinated nerve cell axons and contain few or no neural cell bodies or dendrites. http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx http://purl.obolibrary.org/obo/UBERON_0002360 meninx A meninx that is part of a brain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx A meninx that is part of a forebrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003556 forebrain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges An arachnoid mater that is part of a forebrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003557 midbrain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003288 meninx of midbrain An arachnoid mater that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003558 diencephalon arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003556 forebrain arachnoid mater An arachnoid mater that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003559 hindbrain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003291 meninx of hindbrain An arachnoid mater that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003560 spinal cord arachnoid mater http://purl.obolibrary.org/obo/UBERON_0002362 arachnoid mater An arachnoid mater that is part of a spinal cord [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003561 forebrain dura mater http://purl.obolibrary.org/obo/UBERON_0003548 forebrain meninges A dura mater that is part of a forebrain. http://purl.obolibrary.org/obo/UBERON_0003562 midbrain dura mater http://purl.obolibrary.org/obo/UBERON_0003288 meninx of midbrain A dura mater that is part of a midbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003563 telencephalon dura mater http://purl.obolibrary.org/obo/UBERON_0003561 forebrain dura mater A dura mater that is part of a telencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003564 diencephalon dura mater http://purl.obolibrary.org/obo/UBERON_0003561 forebrain dura mater A dura mater that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003565 hindbrain dura mater http://purl.obolibrary.org/obo/UBERON_0003291 meninx of hindbrain A dura mater that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003567 abdomen connective tissue http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment connective tissue A portion of connective tissue that is part of an abdomen [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003568 neck connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003571 trachea connective tissue http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue A portion of connective tissue that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue A portion of connective tissue that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003583 larynx connective tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue A portion of connective tissue that is part of a larynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003585 dermis connective tissue http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A portion of connective tissue that is part of a dermis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003592 bronchus connective tissue http://purl.obolibrary.org/obo/UBERON_0003580 lower respiratory tract connective tissue A portion of connective tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003593 thoracic cavity connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a thoracic cavity [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003601 neck cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage http://purl.obolibrary.org/obo/UBERON_0003406 cartilage of respiratory system A cartilage that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003604 trachea cartilage http://purl.obolibrary.org/obo/UBERON_0003603 lower respiratory tract cartilage The ring-shaped cartilaginous structures that support the trachea. http://purl.obolibrary.org/obo/UBERON_0003605 eye skin gland http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region A skin gland that is part of a camera-type eye [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003609 aorta elastic tissue http://purl.obolibrary.org/obo/UBERON_0003614 blood vessel elastic tissue The dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall. http://purl.obolibrary.org/obo/UBERON_0003610 heart elastic tissue http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue The type of heart connective tissue found in the endocardial layer that consists mainly of elastic fibers. http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue http://purl.obolibrary.org/obo/UBERON_0003570 respiratory system connective tissue An elastic tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003613 cardiovascular system elastic tissue http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue An elastic tissue that is part of a circulatory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003614 blood vessel elastic tissue http://purl.obolibrary.org/obo/UBERON_0003613 cardiovascular system elastic tissue Elastic tissue layer that lines a blood vessel layer. http://purl.obolibrary.org/obo/UBERON_0003615 lung elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue Elastic tissue that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003616 bronchus elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue An elastic tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003617 trachea elastic tissue http://purl.obolibrary.org/obo/UBERON_0003611 respiratory system elastic tissue An elastic tissue that is part of a trachea [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003618 aorta tunica media http://purl.obolibrary.org/obo/UBERON_0002522 tunica media The middle layer of the aorta wall, containing the smooth muscle layer and elastic fibers. http://purl.obolibrary.org/obo/UBERON_0003619 aorta tunica intima http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer The innermost layer of the aorta, containing the endothelium and an inner elastic membrane. http://purl.obolibrary.org/obo/UBERON_0003643 respiratory system arterial blood vessel http://purl.obolibrary.org/obo/UBERON_0003509 arterial blood vessel An arterial blood vessel that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003684 abdominal cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The part of the ventral body cavity that is within the abdomen proper (excluding the pelvic cavity). http://purl.obolibrary.org/obo/UBERON_0003685 cranial suture http://purl.obolibrary.org/obo/UBERON_0009198 craniofacial suture Fibrous joint in which the articulating bones or cartilages of the skull are connected by sutural ligaments (scant amount of collagenous dense connective tissue). Examples: sagittal suture, frontal suture. http://purl.obolibrary.org/obo/UBERON_0003697 abdominal wall http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall The tissues that surround the organs that are present within the abdominal cavity. The abdominal wall tissue is composed of layers of fat, parietal peritoneum, fascia, and muscles. http://purl.obolibrary.org/obo/UBERON_0003709 circle of Willis http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery A circle of arteries that supply blood to the brain. The Circle of Willis comprises the following arteries: Anterior cerebral artery (left and right); Anterior communicating artery; Internal carotid artery (left and right); Posterior cerebral artery (left and right); Posterior communicating artery (left and right).The basilar artery and middle cerebral arteries, supplying the brain, are also considered part of the circle. http://purl.obolibrary.org/obo/UBERON_0003711 brachiocephalic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The left and right brachiocephalic veins in the upper chest are formed by the union of each corresponding internal jugular vein and subclavian vein. This is at the level of the sternoclavicular joint. These great vessels merge to form the superior vena cava. The brachiocephalic veins are the major veins returning blood to the superior vena cava. http://purl.obolibrary.org/obo/UBERON_0003714 neural tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue in the nervous system which consists of neurons and glial cells, and may also contain parts of the vasculature. http://purl.obolibrary.org/obo/UBERON_0003715 splanchnic nerve http://purl.obolibrary.org/obo/UBERON_0034729 sympathetic nerve The major nerves supplying sympathetic innervation to the abdomen, including the greater, lesser, and lowest (or smallest) splanchnic nerves that are formed by preganglionic fibers from the spinal cord which pass through the paravertebral ganglia and then to the celiac ganglia and plexuses and the lumbar splanchnic nerves carry fibers which pass through the lumbar paravertebral ganglia to the mesenteric and hypogastric ganglia. http://purl.obolibrary.org/obo/UBERON_0003716 recurrent laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region A branch of the vagus nerve that supplies motor function and sensation to the larynx (voice box). It travels within the endoneurium. It is the nerve of the 6th Branchial Arch. http://purl.obolibrary.org/obo/UBERON_0003721 lingual nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The lingual nerve is a branch of the mandibular nerve (CN V3), itself a branch of the trigeminal nerve, which supplies sensory innervation to the tongue. It also carries fibers from the facial nerve, which return taste information from the anterior two thirds of the tongue. http://purl.obolibrary.org/obo/UBERON_0003726 thoracic nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The twelve spinal nerves on each side of the thorax. They include eleven INTERCOSTAL NERVES and one subcostal nerve. Both sensory and motor, they supply the muscles and skin of the thoracic and abdominal walls. http://purl.obolibrary.org/obo/UBERON_0003727 intercostal nerve http://purl.obolibrary.org/obo/UBERON_0001780 spinal nerve The intercostal nerves are the anterior divisions (rami anteriores; ventral divisions) of the thoracic spinal nerves from T1 to T11. Each nerve is connected with the adjoining ganglion of the sympathetic trunk by a gray and a white ramus communicans. The intercostal nerves are distributed chiefly to the thoracic pleura and abdominal peritoneum and differ from the anterior divisions of the other spinal nerves in that each pursues an independent course without plexus formation. The first two nerves supply fibers to the upper limb in addition to their thoracic branches; the next four are limited in their distribution to the parietes of the thorax; the lower five supply the parietes of the thorax and abdomen. The 7th intercostal nerve terminates at the xyphoid process, at the lower end of the sternum. The 10th intercostal nerve terminates at the umbilicus. The twelfth thoracic is distributed to the abdominal wall and groin. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa A mucous membrane that lines the mouth. http://purl.obolibrary.org/obo/UBERON_0003824 nerve of thoracic segment http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region A nerve that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003825 nerve of abdominal segment http://purl.obolibrary.org/obo/UBERON_0003439 nerve of trunk region A nerve that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003827 thoracic segment bone http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ A bone that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003828 abdominal segment bone http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element A bone that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003830 thoracic segment muscle http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ Any muscle organ that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Any muscle organ that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003832 esophagus muscle http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any muscle organ that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003833 abdominal segment muscle http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element A muscle organ that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel A blood vessel that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003835 abdominal segment blood vessel http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel A blood vessel that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003836 abdominal segment skin http://purl.obolibrary.org/obo/UBERON_0001085 skin of trunk A skin of body that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue A portion of connective tissue that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003838 abdominal segment connective tissue http://purl.obolibrary.org/obo/UBERON_0003586 trunk connective tissue A portion of connective tissue that is part of an abdominal segment of trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003842 neural tube lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a neural tube. http://purl.obolibrary.org/obo/UBERON_0003848 gonadal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein In medicine, gonadal vein refers to the blood vessel that carrying blood away from the gonad (testis, ovary) toward the heart. Females : ovarian vein Males : testicular vein [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0003849 mesencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a midbrain. http://purl.obolibrary.org/obo/UBERON_0003850 telencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a telencephalon. http://purl.obolibrary.org/obo/UBERON_0003851 diencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a diencephalon. http://purl.obolibrary.org/obo/UBERON_0003852 rhombencephalon neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest A neural crest that has_potential_to_developmentally_contribute_to a hindbrain. http://purl.obolibrary.org/obo/UBERON_0003853 spinal cord neural crest http://purl.obolibrary.org/obo/UBERON_0002342 neural crest A neural crest that has_potential_to_developmentally_contribute_to a spinal cord. http://purl.obolibrary.org/obo/UBERON_0003854 spinal cord neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a future spinal cord. http://purl.obolibrary.org/obo/UBERON_0003855 gonad mesenchyme http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Mesenchyme that is part of a developing gonad [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003869 presumptive ganglion http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a ganglion. http://purl.obolibrary.org/obo/UBERON_0003886 future coelemic cavity lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that has the potential to develop into a coelemic cavity lumen. http://purl.obolibrary.org/obo/UBERON_0003887 intraembryonic coelom http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The part of the coelom in the embryo between the somatopleuric and splanchnopleuric mesoderm; the principal body cavities of the trunk (thoracic, abdominal, and pelvic) arise from this embryonic part of the coelom. http://purl.obolibrary.org/obo/UBERON_0003891 stroma http://purl.obolibrary.org/obo/UBERON_0000064 organ part Connective, non-functional supportive framework of a biological cell, tissue, or organ. Contrast with parenchyma. http://purl.obolibrary.org/obo/UBERON_0003897 axial muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate One of the skeletal muscles of the head and neck, spine, and ribs. http://purl.obolibrary.org/obo/UBERON_0003898 skeletal muscle tissue of trunk http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue in the trunk. http://purl.obolibrary.org/obo/UBERON_0003902 retinal neural layer http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The part of the retina that contains neurons and photoreceptor cells[GO]. http://purl.obolibrary.org/obo/UBERON_0003909 sinusoid http://purl.obolibrary.org/obo/UBERON_2005260 fenestrated capillary Small blood vessel similar to a capillary but with a fenestrated endothelium. Sinusoids are found in the liver, lymphoid tissue, endocrine organs, and hematopoietic organs such as the bone marrow and the spleen. Sinusoids found within terminal villi of the placenta are not comparable to these; they possess a continuous endothelium and complete basal lamina[WP]. http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium The epithelial component of the choroid plexus. Consists of cuboidal epithelial cells surrounding a core of capillaries and loose connective tissue. http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/UBERON_0003915 endothelial tube http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube Any endothelium that has the quality of being cylindrical [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003920 venous blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that carries blood from the capillaries toward the heart. http://purl.obolibrary.org/obo/UBERON_0003928 digestive system duct http://purl.obolibrary.org/obo/UBERON_0000058 duct A duct that is part of a digestive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that lines the lumen of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0003931 diencephalic white matter http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain White matter that is part of a diencephalon [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0003932 cartilage element of chondrocranium http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage A cartilage element of chondrocranium. Example: neurocranial trabecula. http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element A cartilage element that is part of the cranial skeleton. http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure Any of the organized aggregations of cells that function as secretory or excretory organs and are associated with reproduction. http://purl.obolibrary.org/obo/UBERON_0003942 somatosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system The sensory system for the sense of touch and pain. http://purl.obolibrary.org/obo/UBERON_0003947 brain ventricle/choroid plexus http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure The brain ventricles or their associated choroid plexuses. http://purl.obolibrary.org/obo/UBERON_0003952 anterior stroma of cornea http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue The anterior segment of the lamellated connective tissue layer of the cornea. http://purl.obolibrary.org/obo/UBERON_0003953 posterior stroma of cornea http://purl.obolibrary.org/obo/UBERON_0003566 head connective tissue The posterior segment of the lamellated connective tissue layer of the cornea. http://purl.obolibrary.org/obo/UBERON_0003967 cutaneous elastic tissue http://purl.obolibrary.org/obo/UBERON_0002521 elastic tissue The slender connective tissue fiber in the extracellular matrix of skin tissue that is composed of microfibrils and amorphous elastin and is characterized by great elasticity. http://purl.obolibrary.org/obo/UBERON_0003975 internal female genitalia http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia The internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina. http://purl.obolibrary.org/obo/UBERON_0004015 embryonic-extraembryonic boundary http://purl.obolibrary.org/obo/UBERON_0000015 non-material anatomical boundary The connection between the embryo proper and extraembryonic tissues. http://purl.obolibrary.org/obo/UBERON_0004016 dermatome http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure A transitional population of migrating mesenchymal cells that derive from somites and that will become dermal cells. http://purl.obolibrary.org/obo/UBERON_0004022 germinal neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The single layer of epithelial cells that lines the early neural tube and develops into the nervous system and into the neural crest cells. http://purl.obolibrary.org/obo/UBERON_0004023 ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The transient proliferative population of neurons that expands exponentially during late prenatal development; it is a continuous germinal zone distinct from the ventricular zone that surrounds the brain ventricles[MP]. http://purl.obolibrary.org/obo/UBERON_0004024 medial ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the neocortex; however, hippocampal neurons, thalamus, septum and olfactory bulb neurons are also partly derived from the MGE. http://purl.obolibrary.org/obo/UBERON_0004025 lateral ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE. http://purl.obolibrary.org/obo/UBERON_0004026 caudal ganglionic eminence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The caudally located, distinct elevation of a transient proliferating cell mass of the fetal subventricular zone, located adjacent to the lateral ventricle. http://purl.obolibrary.org/obo/UBERON_0004035 cortical subplate http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The transient outer neural tube region that contains the first generated post-mitotic neurons that receive synaptic input from thalamic axons and in turn project axons to the developing cortical plate. http://purl.obolibrary.org/obo/UBERON_0004040 cortical intermediate zone http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The region of the developing mammalian cortex that extends between the ventricular zone and the cortical plate (CP); normally, the IZ is a region of tangential migration of cells, and at midgestation, the lower part of the IZ develops into the subventricular zone. http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium The layer of undifferentiated, proliferating cells that line the neural tube lumen that is the immediate transformation of the germinal neuroepithelium. http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium The layer of glia and differentiating neurons that forms as a second layer around the germinal neuroepithium; as this develops it comes to lie between the ventricular and marginal layers and includes the basal and alar plates. Develops into neurons and glia forming a gray matter layer. http://purl.obolibrary.org/obo/UBERON_0004062 neural tube marginal layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure The outermost layer of the neural tube that consists of axons from the developing mantle layer and will form the white matter. http://purl.obolibrary.org/obo/UBERON_0004063 spinal cord alar plate http://purl.obolibrary.org/obo/UBERON_0005882 neural tube alar plate The region of the mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses; the alar plate develops into the dorsal horn in the grey matter of the spinal cord. http://purl.obolibrary.org/obo/UBERON_0004064 neural tube basal plate http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The region of the mantle layer of the neural tube that lies ventral to the sulcus limitans and contains primarily motor neurons and interneurons. http://purl.obolibrary.org/obo/UBERON_0004087 vena cava http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart Any of the veins that carries deoxygenated blood from a part of the body into the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0004088 orbital region http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head The subdivision of the face that includes the eye (eyeball plus adnexa such as eyelids) and the orbit of the skull and associated parts of the face such as the eyebrows, if present. http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any tube, opening or passage that connects two distinct anatomical spaces. http://purl.obolibrary.org/obo/UBERON_0004118 vasculature of iris http://purl.obolibrary.org/obo/UBERON_0002203 vasculature of eye A vasculature that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the endoderm. http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the mesoderm. http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that develops (entirely or partially) from the ectoderm. http://purl.obolibrary.org/obo/UBERON_0004128 optic vesicle http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. http://purl.obolibrary.org/obo/UBERON_0004130 cerebellar layer http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer A cortical cell layer of the cerebellum. Examples: the granular (inner+outer) layer, molecular layer, Purkinje cell layer, and the ventricular layer of the embryo. http://purl.obolibrary.org/obo/UBERON_0004133 salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Missing definition for term UBERON:0004133. Please replace it using linked reference. http://purl.obolibrary.org/obo/UBERON_0004139 cardiogenic plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The first recognizable structure derived from the heart field. http://purl.obolibrary.org/obo/UBERON_0004140 primary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle. http://purl.obolibrary.org/obo/UBERON_0004141 heart tube http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium An epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/UBERON_0004142 outflow tract septum http://purl.obolibrary.org/obo/UBERON_0002099 cardiac septum The outflow tract septum is a partition in the outflow tract. http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/UBERON_0004146 His-Purkinje system http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/UBERON_0004148 cardiac vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein Vein of heart that drains the myocardium. http://purl.obolibrary.org/obo/UBERON_0004151 cardiac chamber http://purl.obolibrary.org/obo/UBERON_0000064 organ part A cardiac chamber surrounds an enclosed cavity within the heart. http://purl.obolibrary.org/obo/UBERON_0004160 proepicardium http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme An embryonic group of progenitor cells that forms from an outpouching of the septum transversum near the venous pole of the heart and gives rise to the epicardium. http://purl.obolibrary.org/obo/UBERON_0004161 septum transversum http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme A thick plate of mesodermal tissue that occupies the space between the thoracic cavity and yolk stalk in the early embryo, forming a transverse partition partially separating the coelomic cavity into thoracic and abdominal portions. It gives rise to the central tendon of the diaphragm[VHOG]. http://purl.obolibrary.org/obo/UBERON_0004175 internal genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/UBERON_0003133 reproductive organ The external genitalia are the outer sex organs, such as the penis or vulva in mammals. http://purl.obolibrary.org/obo/UBERON_0004177 hemopoietic organ http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ that is part of the hematopoietic system. http://purl.obolibrary.org/obo/UBERON_0004178 aorta smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle The nonstriated, involuntary muscle tissue located in the wall of the aorta. http://purl.obolibrary.org/obo/UBERON_0004185 endodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portions of the gut that is derived from endoderm. http://purl.obolibrary.org/obo/UBERON_0004215 back nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004225 respiratory system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle http://purl.obolibrary.org/obo/UBERON_0004225 respiratory system smooth muscle A portion of smooth muscle tissue that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004234 iris smooth muscle http://purl.obolibrary.org/obo/UBERON_0003386 smooth muscle of eye A portion of smooth muscle tissue that is part of a iris [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004236 arteriole smooth muscle http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle A portion of smooth muscle tissue that is part of an arteriole [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue Smooth muscle found within, and composing the majority of the wall of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004242 bronchus smooth muscle http://purl.obolibrary.org/obo/UBERON_0004233 lower respiratory tract smooth muscle A portion of smooth muscle tissue that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004246 outflow tract smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004247 bone of dorsum http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element A bone that is part of the dorsal region of an animal. http://purl.obolibrary.org/obo/UBERON_0004253 skin muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Any muscle organ that is part of a skin of body [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004258 back blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004265 outflow tract myocardium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium A myocardium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004267 back connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A portion of connective tissue that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004271 outflow tract pericardium http://purl.obolibrary.org/obo/UBERON_0002407 pericardium A pericardium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004273 cartilaginous joint suture http://purl.obolibrary.org/obo/UBERON_0003685 cranial suture A cranial suture that is part of a cartilaginous joint [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004274 lateral ventricle choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium A choroid plexus epithelium that is part of a lateral ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004275 third ventricle choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium A choroid plexus epithelium that is part of a third ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004276 fourth ventricle choroid plexus epithelium http://purl.obolibrary.org/obo/UBERON_0003911 choroid plexus epithelium A choroid plexus epithelium that is part of a fourth ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle that is part of the eye region. http://purl.obolibrary.org/obo/UBERON_0004288 skeleton http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical cluster that consists of all the skeletal elements (eg., bone, cartilage, and teeth) of the body. http://purl.obolibrary.org/obo/UBERON_0004290 dermomyotome http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure The bilaminar epithelium formed from the myotome and dermatome. http://purl.obolibrary.org/obo/UBERON_0004291 heart rudiment http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium A cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/UBERON_0004292 cardiac skeleton http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue Dense connective tissue that separates the atria from the ventricles and provides physical support for the heart. http://purl.obolibrary.org/obo/UBERON_0004293 parasympathetic nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a parasympathetic nervous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004297 respiratory system blood vessel smooth muscle http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle A blood vessel smooth muscle that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004345 trophectoderm http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Outermost layer of cells in the blastodermic vesicle, which will develop into the trophoblast layer and then contact the endometrium and take part in establishing the embryo's means of nutrition. http://purl.obolibrary.org/obo/UBERON_0004348 optic eminence http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic structure that gives rise to the corneal ectoderm. http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Multilayered ectodermal region at the distal tip of a limb or fin bud necessary for the proper development of the underlying mesenchyme[MP,modified]. Along with the zone of polarizing activity, it is a crucial organizing region during limb development[WP]. http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure An outgrowth on the lateral trunk of the embryo that develops into a limb or paired fin. The limb/fin bud is divided into ectoderm and mesenchyme[cjm, modified from MP]. http://purl.obolibrary.org/obo/UBERON_0004362 pharyngeal arch 1 http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch The first of the series of pharyngeal arches that develop into jaw bones or their homologs, and their associated nerves and arteries. http://purl.obolibrary.org/obo/UBERON_0004364 ectoplacental cone http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Thickened trophoblast of the blastocyst in rodents that becomes the fetal portion of the placenta. http://purl.obolibrary.org/obo/UBERON_0004365 vitelline blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel Blood vessel that is connected to the yolk sac. http://purl.obolibrary.org/obo/UBERON_0004367 Descemet's membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A transparent homogeneous acellular layer found between the substantia propria and the endothelial layer of the cornea[MP]. http://purl.obolibrary.org/obo/UBERON_0004370 anterior limiting lamina of cornea http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A transparent homogeneous acellular layer, 6 to 9 um thick, lying between the basal lamina of the outer layer of stratified epithelium and the substantia propria of the cornea; it is considered to be a basement membrane. http://purl.obolibrary.org/obo/UBERON_0004374 vitelline vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature Vascular network that is connected to the yolk sac. http://purl.obolibrary.org/obo/UBERON_0004375 bone of free limb or fin http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of an appendage [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004449 cerebral artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery One of three main pairs of arteries and their branches, which irrigate the cerebrum of the brain. http://purl.obolibrary.org/obo/UBERON_0004455 neurula embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo An embryo at the neurula stage. http://purl.obolibrary.org/obo/UBERON_0004456 entire sense organ system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system Sum of all sensory systems in an organism. http://purl.obolibrary.org/obo/UBERON_0004461 skeletal musculature of head http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature Any collection of skeletal muscles that is part of a head [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004464 musculature of thorax http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk Any collection of muscles that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004465 musculature of neck http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a neck [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004469 musculature of back http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a back [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004471 musculature of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex A subdivision of the musculature of the body in the pectoral girdle region. Includes pectoral and shoulder muscles. http://purl.obolibrary.org/obo/UBERON_0004473 musculature of face http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature Any collection of muscles that is part of a face. http://purl.obolibrary.org/obo/UBERON_0004478 musculature of larynx http://purl.obolibrary.org/obo/UBERON_0001015 musculature The collection of muscles that are part of the larynx. http://purl.obolibrary.org/obo/UBERON_0004479 musculature of trunk http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a trunk [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004490 cardiac muscle tissue of atrium http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium A portion of cardiac muscle tissue that is part of an atrium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004491 cardiac muscle tissue of interatrial septum http://purl.obolibrary.org/obo/UBERON_0004492 cardiac muscle tissue of cardiac septum A portion of cardiac muscle tissue that is part of a interatrial septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004492 cardiac muscle tissue of cardiac septum http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue A portion of cardiac muscle tissue that is part of a cardiac septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue A portion of cardiac muscle tissue that is part of a myocardium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004495 skeletal muscle tissue of diaphragm http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle A portion of skeletal muscle tissue that is part of a diaphragm [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004521 vasculature of muscle organ http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a muscle organ [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004522 vasculature of musculoskeletal system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a musculoskeletal system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vascular network consisting of blood vessels. http://purl.obolibrary.org/obo/UBERON_0004548 left eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An eye that is part of a left side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004549 right eye http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An eye that is part of a right side of organism [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004571 systemic arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the arterial system which carries oxygenated blood away from the heart to the body, and returns deoxygenated blood back to the heart. http://purl.obolibrary.org/obo/UBERON_0004572 arterial system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all arteries. http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery of the systemic circulation, which is the part of the cardiovascular system which carries oxygenated blood away from the heart, to the body, and returns deoxygenated blood back to the heart. http://purl.obolibrary.org/obo/UBERON_0004581 systemic venous system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the venous system that drains the general body tissues[Kardong]. http://purl.obolibrary.org/obo/UBERON_0004582 venous system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all venous vessels. In vertebrates with a double circulation, this can be divided into systemic and pulmonary portions. http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that lines the blood vasculature. Other endothelia may line lymph vessels, the heart. http://purl.obolibrary.org/obo/UBERON_0004642 third ventricle ependyma http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma An ependyma that is part of a third ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004643 lateral ventricle ependyma http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma An ependyma that is part of a lateral ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004644 fourth ventricle ependyma http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma An ependyma that is part of a fourth ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004663 aorta wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel An anatomical wall that is part of an aorta, enclosing the luminal space. http://purl.obolibrary.org/obo/UBERON_0004664 aorta tunica adventitia http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel The outermost layer of the aorta wall, containing connective tissue and collagen and elastic fibers. http://purl.obolibrary.org/obo/UBERON_0004666 interventricular septum membranous part http://purl.obolibrary.org/obo/UBERON_0005983 heart layer The membranous portion of the wall between the two lower chambers of the heart. http://purl.obolibrary.org/obo/UBERON_0004667 interventricular septum muscular part http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue The muscular portion of the wall between the two lower chambers of the heart. http://purl.obolibrary.org/obo/UBERON_0004668 fourth ventricle aperture http://purl.obolibrary.org/obo/UBERON_0000161 orifice One of: the 4th ventricle median or lateral apertures. http://purl.obolibrary.org/obo/UBERON_0004670 ependyma http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The thin epithelium-like membrane composed of ependymal cells that lines the ventricular system of the brain and the spinal cord. http://purl.obolibrary.org/obo/UBERON_0004684 raphe nuclei http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The raphe nuclei are thin plates of cells in and immediately adjacent to the sagittal plane. http://purl.obolibrary.org/obo/UBERON_0004688 costo-cervical trunk http://purl.obolibrary.org/obo/UBERON_0001637 artery The costocervical trunk arises from the upper and back part of the subclavian artery, behind the scalenus anterior on the right side, and medial to that muscle on the left side. Passing backward, it splits into the deep cervical artery and the supreme intercostal artery (or the Highest intercostal artery), which descends behind the pleura in front of the necks of the first and second ribs, and anastomoses with the first aortic intercostal (3rd posterior intercostal artery). As it crosses the neck of the first rib it lies medial to the anterior division of the first thoracic nerve, and lateral to the first thoracic ganglion of the sympathetic trunk. In the first intercostal space, it gives off a branch which is distributed in a manner similar to the distribution of the aortic intercostals. The branch for the second intercostal space usually joins with one from the highest aortic intercostal artery. This branch is not constant, but is more commonly found on the right side; when absent, its place is supplied by an intercostal branch from the aorta. Each intercostal gives off a posterior branch which goes to the posterior vertebral muscles, and sends a small spinal branch through the corresponding intervertebral foramen to the medulla spinalis and its membranes. [WP,unvetted]. http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A portion of smooth muscle tissue that is part of an arterial system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle http://purl.obolibrary.org/obo/UBERON_0004237 blood vessel smooth muscle A portion of smooth muscle tissue that is part of a venous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004698 vena cava endothelium http://purl.obolibrary.org/obo/UBERON_0001919 endothelium of vein An endothelium that is part of a vena cava [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004699 outflow tract endothelium http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium An endothelium that is part of a outflow tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of an arterial system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004701 venous system endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of a venous system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium A blood vessel endothelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004706 bulbus cordis http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A transient fetal dilation of the distal (or cranial) heart tube located where the arterial trunk joins the ventral roots of the aortic arches. http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An appendage that is part of an appendage girdle complex. http://purl.obolibrary.org/obo/UBERON_0004710 pectoral appendage http://purl.obolibrary.org/obo/UBERON_0004708 paired limb/fin Paired appendage that consists of the anterior appendicular skeleton and associated soft and hard tissues, but excludes the pectoral girdle and its associated soft and hard tissues. http://purl.obolibrary.org/obo/UBERON_0004711 jugular vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The jugular veins are veins that bring deoxygenated blood from the head back to the heart via the superior vena cava. http://purl.obolibrary.org/obo/UBERON_0004716 conceptus http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure The embryo and its adnexa (appendages or adjunct parts) or associated membranes (i.e. the products of conception) The conceptus includes all structures that develop from the zygote, both embryonic and extraembryonic. It includes the embryo as well as the embryonic part of the placenta and its associated membranes - amnion, chorion (gestational sac), and yolk sac[WP]. http://purl.obolibrary.org/obo/UBERON_0004725 piriform cortex http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain The subdivision of the laminated olfactory cortex with only three main layers that receive monosynaptic input from the olfactory bulb via the lateral olfactory tract; it is located bilaterally in the ventrolateral forebrain and is commonly divided into anterior and posterior regions. http://purl.obolibrary.org/obo/UBERON_0004731 neuromere http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system A transverse unitary subdivision of the neural tube that shares a common dorsoventral structure (floor, basal, alar, and roof plates), but each having differential molecular identities and fates; they comprise the secondary prosencephalon, diencephalon (prosomeres), the midbrain (mesomeres), and the hindbrain (rhombomeres). http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit Any segmental subdivision of a nervous system. Includes metameric developmental segments, such as vertebrates neuromeres. http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain http://purl.obolibrary.org/obo/UBERON_0004732 segmental subdivision of nervous system An organ subunit that is part of a hindbrain [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004734 gastrula http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the gastrula stage. http://purl.obolibrary.org/obo/UBERON_0004742 dentary http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure The dentary is a dermal bone that forms the antero-lateral part of the lower jaw in fishes and amphibians, extending to the whole lower jaw in mammals[VHOG,modified]. http://purl.obolibrary.org/obo/UBERON_0004755 skeletal tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A specialized form of connective tissue in which the extracellular matrix is firm, providing the tissue with resilience, and/or mineralized and that functions in mechanical and structural support.[VSAO]. http://purl.obolibrary.org/obo/UBERON_0004756 dermal skeletal element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Dermis-derived entity that is made of skeletal tissue. http://purl.obolibrary.org/obo/UBERON_0004761 cartilaginous neurocranium http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The primitive cartilagionous skeletal structure of the fetal skull that grows to envelop the rapidly growing embyonic brain. In humans, the chondrocranium begins forming at 28 days from mesenchymal condensations and is fully formed between week 7 and 9 of fetal development. While the majority of the chondrocranium is succeeded by the bony skull in most higher vertebrates, some components do persist into adulthood.[1] In Cartilagious fishes and Agnathans, the chondrocranium persist throughout life.[2] Embryologically, the chondrocranium represent the basal cranial structure, and lay the base for the formation of the endocranium in higher vertebrates[WP]. http://purl.obolibrary.org/obo/UBERON_0004764 intramembranous bone tissue http://purl.obolibrary.org/obo/UBERON_0002481 bone tissue Bone tissue that forms directly within mesenchyme, and does not replace other tissues[TAO]. Intramembranous ossification is the formation of bone in which osteoblasts secrete a collagen-proteoglycan matrix that binds calcium salts and becomes calcified[GO]. Intramembranous ossification is the way flat bones and the shell of a turtle are formed[GO]. Unlike endochondral ossification, cartilage is not present during intramembranous ossification[WP]. http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ consisting of skeletal tissue. Encompasses whole bones, fused bones, cartilaginious elements, teeth, dermal denticles. http://purl.obolibrary.org/obo/UBERON_0004766 cranial bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a cranium. http://purl.obolibrary.org/obo/UBERON_0004768 bone of lower jaw http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw Any bone that is part of the lower jaw skeleton. This includes (when present): the dentary/mandible, the articular, the splenial, the suprangular. http://purl.obolibrary.org/obo/UBERON_0004770 articular system http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection Anatomical system that consists of all the joints of the body. http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa http://purl.obolibrary.org/obo/UBERON_0000009 submucosa A submucosa that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004778 larynx submucosa http://purl.obolibrary.org/obo/UBERON_0004777 respiratory system submucosa A submucosa that is part of a larynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004779 respiratory system lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart An anatomical wall that is part of a cardiac ventricle [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004785 respiratory system mucosa http://purl.obolibrary.org/obo/UBERON_0000344 mucosa The mucous membrane lining the respiratory tract. http://purl.obolibrary.org/obo/UBERON_0004794 esophagus secretion http://purl.obolibrary.org/obo/UBERON_0000456 secretion of exocrine gland A secretion that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Any of the tissue layers that comprise a blood vessel. Examples: tunica media, tunica adventitia. http://purl.obolibrary.org/obo/UBERON_0004798 respiratory system basal lamina http://purl.obolibrary.org/obo/UBERON_0000482 basal lamina of epithelium A basal lamina that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004799 trachea basal lamina http://purl.obolibrary.org/obo/UBERON_0004798 respiratory system basal lamina A basal lamina that is part of a respiratory airway [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004800 bronchus basal lamina http://purl.obolibrary.org/obo/UBERON_0004799 trachea basal lamina A basal lamina that is part of a bronchus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium The pseudostratified ciliated epithelium that lines much of the conducting portion of the airway, including part of the nasal cavity and larynx, the trachea, and bronchi. http://purl.obolibrary.org/obo/UBERON_0004807 respiratory system epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium An epithelium that is part of a lower respiratory tract [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004816 larynx epithelium http://purl.obolibrary.org/obo/UBERON_0004802 respiratory tract epithelium An epithelium that is part of a larynx [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004830 respiratory system skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004831 esophagus skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a esophagus [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004833 lip skeletal muscle http://purl.obolibrary.org/obo/UBERON_0001134 skeletal muscle tissue A portion of skeletal muscle tissue that is part of a lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004848 respiratory system arterial endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of artery that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004849 respiratory system venous endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium An endothelium of vein that is part of a respiratory system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004851 aorta endothelium http://purl.obolibrary.org/obo/UBERON_0004700 arterial system endothelium The thin layer of flat cells that line the aorta and form a barrier between circulating blood in the lumen and the rest of the vessel wall. http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium An endothelium that is part of the cardiovascular system. http://purl.obolibrary.org/obo/UBERON_0004857 skeletal muscle connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue A connective tissue that surrounds a skeletal muscle tissue. http://purl.obolibrary.org/obo/UBERON_0004859 eye gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a eye. The eye is a compound unit which depending on the species may consist of an eyeballs plus associated ducts and integumentary structures. Eye glands therefore include the various types of lacrimal gland, the various types of apocrine and sebaceous glands associated with the eyelid. http://purl.obolibrary.org/obo/UBERON_0004864 vasculature of retina http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina A vasculature that is part of a retina [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0004872 splanchnic layer of lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Layer of lateral plate mesoderm that forms the circulatory system and future gut wall - overlies endoderm[WP]. http://purl.obolibrary.org/obo/UBERON_0004873 splanchnopleure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the inner (or splanchnic) layer adheres to the endoderm, and with it forms the splanchnopleure[WP]. http://purl.obolibrary.org/obo/UBERON_0004874 somatopleure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure A structure created during embryogenesis when the lateral mesoderm splits into two layers - the outer (or somatic) layer becomes applied to the inner surface of the ectoderm, and with it forms the somatopleure.[WP]. http://purl.obolibrary.org/obo/UBERON_0004880 chordamesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The central region of trunk mesoderm. This tissue forms the notochord. http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The mass of tissue made up of mesenchymal cells in the lung. http://purl.obolibrary.org/obo/UBERON_0004904 neuron projection bundle connecting eye with brain http://purl.obolibrary.org/obo/UBERON_0000122 neuron projection bundle A neuron projection bundle that connects the retina or its analog in the eye with the brain. This includes the vertebrate optic nerve (not truly a nerve) as well as analogous structures such as the Bolwig nerve in Drosophila. http://purl.obolibrary.org/obo/UBERON_0004905 articulation http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical structure that connects two or more adjacent skeletal elements or hardened body parts. http://purl.obolibrary.org/obo/UBERON_0004906 ectodermal part of digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract A portion of the gut that is derived from ectoderm. http://purl.obolibrary.org/obo/UBERON_0004908 upper digestive tract http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract The region of the digestive tract extending from the mouth cavity through pharynx esophagus stomach and duodenum. http://purl.obolibrary.org/obo/UBERON_0004909 epithelium of gonad http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure An epithelium surrounding a gonad. http://purl.obolibrary.org/obo/UBERON_0004911 epithelium of female gonad http://purl.obolibrary.org/obo/UBERON_0004909 epithelium of gonad An epithelium surrounding an ovary. http://purl.obolibrary.org/obo/UBERON_0004921 subdivision of digestive tract http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A proximal-distal subdivision of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0000064 organ part A part of a wall of an organ that forms a layer. http://purl.obolibrary.org/obo/UBERON_0004924 submucosa of pharynx http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract The tissue underlying the tunica mucosa of the pharynx. http://purl.obolibrary.org/obo/UBERON_0005020 mucosa of tongue http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a tongue [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005032 mucosa of lower lip http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip A mucosa that is part of a lower lip [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005056 external female genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia An external genitalia that is part of a female reproductive system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005058 hemolymphoid system gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a hemolymphoid system [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005061 neural groove http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The median dorsal longitudinal groove formed in the embryo by the neural plate after the appearance of the neural folds. http://purl.obolibrary.org/obo/UBERON_0005062 neural fold http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure One of the two elevated edges of the neural groove[GO,MP]. http://purl.obolibrary.org/obo/UBERON_0005068 neural rod http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts[GO]. An intermediate stage in the development of the central nervous system present during the segmentation period; the neural rod is roughly cylindrical in shape, forms from the neural keel, and is not yet hollowed out into the neural tube[ZFIN]. http://purl.obolibrary.org/obo/UBERON_0005075 forebrain-midbrain boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical boundary that adjacent_to a forebrain and adjacent_to a midbrain. http://purl.obolibrary.org/obo/UBERON_0005076 hindbrain-spinal cord boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical boundary that adjacent_to a hindbrain and adjacent_to a spinal cord. http://purl.obolibrary.org/obo/UBERON_0005082 tube lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A hole in a tube[GO]. http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm[GO]. http://purl.obolibrary.org/obo/UBERON_0005090 muscle structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms[GO]. http://purl.obolibrary.org/obo/UBERON_0005153 epithelial bud http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold A bud is a protrusion that forms from an epithelial sheet by localized folding. http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure Any anatomical structure that is part of the reproductive system. http://purl.obolibrary.org/obo/UBERON_0005157 epithelial fold http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet bent on a linear axis. http://purl.obolibrary.org/obo/UBERON_0005158 parenchyma of central nervous system http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma The functional tissue of the central nervous system consisting of neurons and glial cells. http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A structure consisting mainly of cell components, rather than complete cells. http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element An organ or element that is in the abdomen. Examples: spleen, intestine, kidney, abdominal mammary gland. http://purl.obolibrary.org/obo/UBERON_0005173 abdominal segment element http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ or element that is part of the adbominal segment of the organism. This region can be further subdivided into the abdominal cavity and the pelvic region. http://purl.obolibrary.org/obo/UBERON_0005174 dorsal region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the dorsum of the organism. Examples: spinal cord, vertebrae, muscles of back. http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element http://purl.obolibrary.org/obo/UBERON_0000062 organ An organ or element that part of the trunk region. The trunk region can be further subdividied into thoracic (including chest and thoracic cavity) and abdominal (including abdomen and pelbis) regions. http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ An organ or element that is in the thoracic cavity. Examples: lung, heart, longus colli. http://purl.obolibrary.org/obo/UBERON_0005181 thoracic segment organ http://purl.obolibrary.org/obo/UBERON_0005177 trunk region element An organ that part of the thoracic segment region. This region can be further subdividied chest and thoracic cavity regions. http://purl.obolibrary.org/obo/UBERON_0005194 thoracic vein http://purl.obolibrary.org/obo/UBERON_0003834 thoracic segment blood vessel A vein that is part of a thorax [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005204 larynx submucosa gland http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland A gland that is part of a larynx submucosa [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0003891 stroma Stromal matrix surrounding blood vessels within the choroid plexus. http://purl.obolibrary.org/obo/UBERON_0005234 optic eminence ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a optic eminence [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005243 interventricular septum endocardium http://purl.obolibrary.org/obo/UBERON_0002165 endocardium An endocardium that is part of a interventricular septum [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005248 bulbus cordis myocardium http://purl.obolibrary.org/obo/UBERON_0002349 myocardium A myocardium that is part of a bulbus cordis [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005250 stomatodeum gland http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is part of a stomodeum. http://purl.obolibrary.org/obo/UBERON_0005251 yolk sac cavity http://purl.obolibrary.org/obo/UBERON_0012466 extraembryonic cavity An anatomical cavity that is part of a yolk sac [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of primordial embryonic connective tissue of the developing head, consisting of mesenchymal cells supported in interlaminar jelly, that derive mostly from the mesoderm and contribute to head connective tissue, bone and musculature in conjunction with cranial neural crest cells. http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a developing trunk. http://purl.obolibrary.org/obo/UBERON_0005281 ventricular system of central nervous system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system A set of structures containing cerebrospinal fluid in the brain. It is continuous with the central canal of the spinal cord[WP]. http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A structure found in the walls of the ventricles of the brain, consisting of part of the meninges (pia mater in mammals) plus ependyma[cjm]. http://purl.obolibrary.org/obo/UBERON_0005287 tela choroidea of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea Tela chorioidea that lines the fourth ventricle[ZFA]. The tela chorioidea of the fourth ventricle is the name applied to the triangular fold of pia mater which is carried upward between the cerebellum and the medulla oblongata. It consists of two layers, which are continuous with each other in front, and are more or less adherent throughout: The posterior layer covers the antero-inferior surface of the cerebellum. The anterior layer is applied to the structures which form the lower part of the roof of the ventricle, and is continuous inferiorly with the pia mater on the inferior peduncles and closed part of the medulla[WP]. http://purl.obolibrary.org/obo/UBERON_0005288 tela choroidea of third ventricle http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea Tela chorioidea that lines the third ventricle[ZFA]. The part of the choroid plexus in relation to the body of the ventricle forms the vascular fringed margin of a triangular process of pia mater, named the tela chorioidea of the third ventricle, and projects from under cover of the lateral edge of the fornix. Blood is supplied by branches from the superior cerebellar artery[WP]. http://purl.obolibrary.org/obo/UBERON_0005289 tela choroidea of telencephalic ventricle http://purl.obolibrary.org/obo/UBERON_0005283 tela choroidea Tela chorioidea that lines the telencephalic ventricle. http://purl.obolibrary.org/obo/UBERON_0005290 myelencephalon http://purl.obolibrary.org/obo/UBERON_0004733 segmental subdivision of hindbrain The posterior part of the developing vertebrate hindbrain or the corresponding part of the adult brain composed of the medulla oblongata and a portion of the fourth ventricle; as well as the glossopharyngeal nerve (CN IX), vagus nerve (CN X), accessory nerve (CN XI), hypoglossal nerve (CN XII), and a portion of the vestibulocochlear nerve (CN VIII).[BTO,WP]. http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue A portion of tissue that is part of an embryo. http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue that is contiguous with the embryo and is comprised of portions of tissue or cells that will not contribute to the embryo. http://purl.obolibrary.org/obo/UBERON_0005316 endocardial endothelium http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium The endothelial lining of the endocardium. http://purl.obolibrary.org/obo/UBERON_0005317 pulmonary artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery An pulmonary artery endothelium is an epithelium that lines the pulmonary artery[GO]. http://purl.obolibrary.org/obo/UBERON_0005334 oral lamina propria http://purl.obolibrary.org/obo/UBERON_0000030 lamina propria A lamina propria that is part of a mucosa of oral region. http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract A ventricular outflow tract is a portion of either the left ventricle or right ventricle of the heart through which blood passes in order to enter the great arteries. The right ventricular outflow tract (RVOT) is an infundibular extension of the ventricular cavity which connects to the pulmonary artery. The left ventricular outflow tract (LVOT), which connects to the aorta, is nearly indistinguishable from the rest of the ventricle[WP]. http://purl.obolibrary.org/obo/UBERON_0005338 outflow tract aortic component http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract An outflow tract that is part of a aorta. http://purl.obolibrary.org/obo/UBERON_0005343 cortical plate http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers[MP]. http://purl.obolibrary.org/obo/UBERON_0005357 brain ependyma http://purl.obolibrary.org/obo/UBERON_0004670 ependyma The ependymal cell layer that lines the brain ventricles. http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer in the central nervous system that lines system of communicating cavities in the brain and spinal cord. http://purl.obolibrary.org/obo/UBERON_0005359 spinal cord ependyma http://purl.obolibrary.org/obo/UBERON_0004670 ependyma The ependymal cell layer that lines the spinal cord. http://purl.obolibrary.org/obo/UBERON_0005362 vagus X ganglion http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglion The group of sensory neuron cell bodies associated with the vagus nerve. http://purl.obolibrary.org/obo/UBERON_0005366 olfactory lobe http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere The lobe at the anterior part of each cerebral hemisphere, responsible for olfactory functions. http://purl.obolibrary.org/obo/UBERON_0005382 dorsal striatum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon Dorsal components of the striatum comprising the caudate nucleus and the putamen, in species that have distinct nuclei; the caudoputamen in species which don't. http://purl.obolibrary.org/obo/UBERON_0005383 caudate-putamen http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster Regional part of telencephalon in some species, e.g., rodent, equivalent to the dorsal striatum (caudate nucleus and putamen). Unlike the dorsal striatum of primates, for example, the caudoputamen is not split into separate nuclei by the fibers of the internal capsule. Rather, the internal capsule splits into fiber bundles which course through the structure. http://purl.obolibrary.org/obo/UBERON_0005388 photoreceptor array http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An array of photoreceptors and any supporting cells found in an eye. http://purl.obolibrary.org/obo/UBERON_0005389 transparent eye structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A transparent structure that is part of a visual sense organ, the function of which is to direct or focus light onto a photoreceptor array. http://purl.obolibrary.org/obo/UBERON_0005397 brain arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003547 brain meninx An arachnoid mater that surrounds a brain. http://purl.obolibrary.org/obo/UBERON_0005398 female reproductive gland http://purl.obolibrary.org/obo/UBERON_0003937 reproductive gland A sex gland that is part of a female reproductive system. http://purl.obolibrary.org/obo/UBERON_0005400 telencephalon arachnoid mater http://purl.obolibrary.org/obo/UBERON_0003556 forebrain arachnoid mater An arachnoid mater that is part of a telencephalon. http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon A gray matter that is part of a cerebral hemisphere. http://purl.obolibrary.org/obo/UBERON_0005403 ventral striatum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon A composite structure of the telencephalon that is defined in the striatopallidal system by connectivity and neurochemical staining. It includes the nucleus accumbens, the most ventral portions of the caudate nucleus and the putamen, the rostrolateral portion of the anterior perforated substance, the islands of Calleja and a rostral subcommissural portion of substantia innominata. The boundary between the ventral striatum and dorsal striatum is indistinct in sections stained for Nissl substance (Heimer-1995; adapted from Brain Info). http://purl.obolibrary.org/obo/UBERON_0005408 circumventricular organ http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Any of any of the secretory or sensory organs located in the brain region around or in relation to the ventricular system that are characterized by extensive vasculature and a lack of a normal blood brain barrier (BBB) and allow for the linkage between the central nervous system and peripheral blood flow. http://purl.obolibrary.org/obo/UBERON_0005419 pectoral appendage bud http://purl.obolibrary.org/obo/UBERON_0004357 paired limb/fin bud A limb bud that develops into a forelimb or pectoral fin. http://purl.obolibrary.org/obo/UBERON_0005421 pectoral appendage apical ectodermal ridge http://purl.obolibrary.org/obo/UBERON_0004356 apical ectodermal ridge An apical ectodermal ridge that is part of a pectoral appendage bud. http://purl.obolibrary.org/obo/UBERON_0005425 presumptive neural retina http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is the inner layer of the optic cup and will become the neural retina. http://purl.obolibrary.org/obo/UBERON_0005426 lens vesicle http://purl.obolibrary.org/obo/UBERON_0000479 tissue Portion of tissue that gives rise to the lens. http://purl.obolibrary.org/obo/UBERON_0005427 corneal primordium http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Portion of tissue that is part of the eye and gives rise to the mature, fully layered cornea. http://purl.obolibrary.org/obo/UBERON_0005428 vagal neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Vagal neural crest is adjacent to the first seven somites gives rise to both ganglionic and ectomesenchymal derivatives[ZFA]. http://purl.obolibrary.org/obo/UBERON_0005432 aortic sac http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel The dilated structure that is lined by endothelial cells and located at the arterial pole of the heart just above (distal to) the truncus arteriosus in mammalian embryos; it is the primordial vascular channel from which the aortic arches (and eventually the dorsal aortae) arise; the aortic sac is homologous to the ventral aorta of gill-bearing vertebrates. http://purl.obolibrary.org/obo/UBERON_0005460 left vitelline vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vitelline vein that is in the left side of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0005472 right vitelline vein http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A vitelline vein that is in the right side of a multicellular organism. http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube http://purl.obolibrary.org/obo/UBERON_0006846 surface groove A longitudinal groove in the neural tube wall that divides the neural tube into dorsal (alar) and ventral (basal) halves (dorsal receives input from sensory neurons, ventral effects motor functions); stretches from the mesencephalon caudad[TMD]. http://purl.obolibrary.org/obo/UBERON_0005487 vitelline vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein The paired veins that carry blood from the yolk sac back to the embryo. http://purl.obolibrary.org/obo/UBERON_0005491 glossopharyngeal neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest Cranial neural crest which gives rise to the glossopharyngeal ganglion. http://purl.obolibrary.org/obo/UBERON_0005496 neural tube lateral wall http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Portion of tissue on the side of the lumen of the neural tube. http://purl.obolibrary.org/obo/UBERON_0005498 primitive heart tube http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Multi-tissue structure that arises from the heart rudiment and will become the heart tube. http://purl.obolibrary.org/obo/UBERON_0005499 rhombomere 1 http://purl.obolibrary.org/obo/UBERON_0001892 rhombomere Hindbrain segment or neuromere 1. http://purl.obolibrary.org/obo/UBERON_0005501 rhombomere lateral wall http://purl.obolibrary.org/obo/UBERON_0005496 neural tube lateral wall A neural tube lateral wall that is part of a rhombomere. http://purl.obolibrary.org/obo/UBERON_0005563 trigeminal neural crest http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population Cranial neural crest which gives rise to the trigeminal ganglion. http://purl.obolibrary.org/obo/UBERON_0005564 gonad primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium Portion of tissue that gives rise to the immature gonad. http://purl.obolibrary.org/obo/UBERON_0005567 rhombomere 1 lateral wall http://purl.obolibrary.org/obo/UBERON_0005501 rhombomere lateral wall A rhombomere lateral wall that is part of a rhombomere 1. http://purl.obolibrary.org/obo/UBERON_0005594 head somite http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Somite located in the head region, caudal to the otic vesicle. http://purl.obolibrary.org/obo/UBERON_0005597 lung primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium A pair of lateral diverticula just over the liver rudiment representing the primordia of the lungs, formed by the floor of the foregut just anterior to the liver diverticulum. http://purl.obolibrary.org/obo/UBERON_0005598 trunk somite http://purl.obolibrary.org/obo/UBERON_0002329 somite A somite that is part of a trunk. http://purl.obolibrary.org/obo/UBERON_0005614 lens anterior epithelium http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium A layer of cuboidal epithelial cells bounded anteriorly by the capsule of the lens and posteriorly by the lens cortex. http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vascular network formed by frequent anastomoses between the blood vessels (arteries or veins) of a part. http://purl.obolibrary.org/obo/UBERON_0005631 extraembryonic membrane http://purl.obolibrary.org/obo/UBERON_0000158 membranous layer Intrinsic membrane that arises from embryonic germ layers and grow to surround the developing embryo. http://purl.obolibrary.org/obo/UBERON_0005638 anterior chamber epithelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An epithelium that is part of a anterior chamber of eyeball. http://purl.obolibrary.org/obo/UBERON_0005656 lens vesicle epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is part of a lens vesicle. http://purl.obolibrary.org/obo/UBERON_0005660 2nd arch ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a pharyngeal arch 2. http://purl.obolibrary.org/obo/UBERON_0005661 3rd arch ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a pharyngeal arch 3. http://purl.obolibrary.org/obo/UBERON_0005662 4th arch ectoderm http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/UBERON_0005664 2nd arch endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a pharyngeal arch 2. http://purl.obolibrary.org/obo/UBERON_0005665 3rd arch endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a pharyngeal arch 3. http://purl.obolibrary.org/obo/UBERON_0005666 4th arch endoderm http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/UBERON_0005669 peritoneal cavity mesothelium http://purl.obolibrary.org/obo/UBERON_0001136 mesothelium A mesothelium that is part of a peritoneal cavity. http://purl.obolibrary.org/obo/UBERON_0005672 right lung endothelium http://purl.obolibrary.org/obo/UBERON_0003364 epithelium of right lung An endothelium that is part of a right lung. http://purl.obolibrary.org/obo/UBERON_0005673 left lung endothelium http://purl.obolibrary.org/obo/UBERON_0003365 epithelium of left lung An endothelium that is part of a left lung. http://purl.obolibrary.org/obo/UBERON_0005688 lens vesicle cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a lens vesicle. http://purl.obolibrary.org/obo/UBERON_0005689 2nd arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 2. http://purl.obolibrary.org/obo/UBERON_0005690 3rd arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 3. http://purl.obolibrary.org/obo/UBERON_0005691 4th arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 4. http://purl.obolibrary.org/obo/UBERON_0005702 optic eminence mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that is part of a optic eminence. http://purl.obolibrary.org/obo/UBERON_0005720 hindbrain venous system http://purl.obolibrary.org/obo/UBERON_0004582 venous system A venous system that is part of a hindbrain. http://purl.obolibrary.org/obo/UBERON_0005723 floor plate spinal cord region http://purl.obolibrary.org/obo/UBERON_0003306 floor plate of neural tube A multi-tissue structure that is part of a spinal cord and is part of a floor plate. http://purl.obolibrary.org/obo/UBERON_0005729 pectoral appendage field http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A limb/fin field that has the potential to develop into a pectoral appendage bud mesenchyme. http://purl.obolibrary.org/obo/UBERON_0005732 paired limb/fin field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A ring of cells capable of forming a limb or paired fin[Gilbert,modified]. http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel http://purl.obolibrary.org/obo/UBERON_0005742 adventitia The outermost layer of a blood vessel, composed mainly of fibrous tissue. http://purl.obolibrary.org/obo/UBERON_0005740 tunica intima of artery http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer A tunica intima that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0005742 adventitia http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An outermost connective tissue covering of an organ, vessel, or other structure[WP]. http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit Anatomical space that is an opening in a bone, usually for passage of blood vessels or nerves. http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure An acellular anatomical structure that is the bounding layer of a anatomical structure. http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium http://purl.obolibrary.org/obo/UBERON_0005764 acellular membrane An acellular membrane that is part of the epithelium, lies adjacent to the epithelial cells, and is the fusion of the the basal lamina and the reticular lamina. http://purl.obolibrary.org/obo/UBERON_0005800 section of aorta http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube Any portion of the aorta including the ascending and descending aorta, and aortic arch or a portion of the aortic orifice of the left ventricle. http://purl.obolibrary.org/obo/UBERON_0005805 dorsal aorta http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/UBERON_0005837 fasciculus of spinal cord http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A fascicle that is part of a spinal cord. http://purl.obolibrary.org/obo/UBERON_0005838 fasciculus of brain http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster A fascicle that is part of a brain. http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation A delimited region of dense mesenchyme within looser mesenchyme. http://purl.obolibrary.org/obo/UBERON_0005863 cartilaginous condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation Cell condensation that is an aggregation of mesenchymal cells that are committed to differentiate into chondroblasts and chondrocytes. http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation A delimited region of dense mesenchyme within looser mesenchyme whose cells are committed to become chondroblasts. http://purl.obolibrary.org/obo/UBERON_0005867 mandibular prominence http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence The paired ventral prominences formed by bifurcation of the first pharyngeal arches in the embryo; the two prominences unite ventrally and fuse to form the mandible and lower lip. http://purl.obolibrary.org/obo/UBERON_0005882 neural tube alar plate http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The mantle layer of the neural tube that lies dorsal to the sulcus limitans and contains primarily sensory neurons and interneurons involved in communication of sensory impulses. http://purl.obolibrary.org/obo/UBERON_0005884 hyoid arch skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton A subdivision of skeleton that supports pharyngeal arch 2. http://purl.obolibrary.org/obo/UBERON_0005902 occipital region http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Anatomical cluster that is located in the posterior region of the cranium and forms the margin of the foramen magnum and occipital condyles. http://purl.obolibrary.org/obo/UBERON_0005906 serous sac http://purl.obolibrary.org/obo/UBERON_0000062 organ Organ with organ cavity, which has as parts a serous membrane and a serous cavity . Examples: pleural sac, pericardial sac, tendon sheath, bursa.[FMA]. http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium http://purl.obolibrary.org/obo/UBERON_0004119 endoderm-derived structure Epithelium that derives from the endoderm. Examples: urothelium, transitional epithelium of ureter, epithelium of prostatic gland.[FMA]. http://purl.obolibrary.org/obo/UBERON_0005944 axial skeleton plus cranial skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeleton which consists of cranial skeleton, set of all vertebrae, set of all ribs and sternum[FMA, modified]. http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract An outflow tract that is part of a cardiac atrium. http://purl.obolibrary.org/obo/UBERON_0005953 outflow part of right ventricle http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle Anteriosuperior, smooth-walled portion of the cavity of the right ventricle, beginning at the supraventricular crest and terminating in the pulmonary trunk. http://purl.obolibrary.org/obo/UBERON_0005956 outflow part of left ventricle http://purl.obolibrary.org/obo/UBERON_0005337 outflow tract of ventricle Anterosuperior fibrous portion of the left ventricle that connects to the ascending aorta. http://purl.obolibrary.org/obo/UBERON_0005965 outflow part of right atrium http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium Outflow part of atrium which consists of wall and cavity of the outflow part of right atrium and the tricuspid valve.[FMA]. http://purl.obolibrary.org/obo/UBERON_0005966 outflow part of left atrium http://purl.obolibrary.org/obo/UBERON_0005946 outflow tract of atrium An outflow tract of atrium that is part of a left atrium. http://purl.obolibrary.org/obo/UBERON_0005979 crista terminalis http://purl.obolibrary.org/obo/UBERON_0000064 organ part The vertical crest of the interior wall of the right atrium that lies to the right of the sinus of the vena cava and separates this from the remainder of the right atrium. http://purl.obolibrary.org/obo/UBERON_0005983 heart layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer The laminar structure of the heart. http://purl.obolibrary.org/obo/UBERON_0005985 coronary vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel Any of the arteries or veins that supply blood to the heart or return blood from the heart muscles to the circulation. http://purl.obolibrary.org/obo/UBERON_0005989 atrioventricular septum http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure The wall of the heart that separates the right atrium and left ventricle; and is located just above the septal cusp of the tricuspid valve. http://purl.obolibrary.org/obo/UBERON_0006002 vitelline artery http://purl.obolibrary.org/obo/UBERON_0004365 vitelline blood vessel The paired arteries that carry blood to the yolk sac from the dorsal aorta. http://purl.obolibrary.org/obo/UBERON_0006003 integumentary adnexa http://purl.obolibrary.org/obo/UBERON_0000064 organ part Anatomical structure embedded in or located in the integument that is part of the integumental system. Examples: hair, follicles, skin glands, claws, nails, feathers. http://purl.obolibrary.org/obo/UBERON_0006098 basal nuclear complex http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain The deep nuclei of telencephalic origin found in the basal region of the forebrain. http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A threadlike extension of a nerve cell and consists of an axon and myelin sheath (if it is myelinated) in the nervous system. There are nerve fibers in the central nervous system and peripheral nervous system. A nerve fiber may be myelinated and/or unmyelinated. In the central nervous system (CNS), myelin by oligodendroglia cells is formed. Schwann cells form myelin in the peripheral nervous system (PNS). Schwann cells also make a thin covering in an axon without myelin (in the PNS). A peripheral nerve fiber contains an axon, myelin sheath, schwann cells and its endoneurium. There are no endoneurium and schwann cells in the central nervous system. http://purl.obolibrary.org/obo/UBERON_0006135 myelinated nerve fiber http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber Axons of neurons encased in a lipoproteinaceous material called myelin. (MeSH). http://purl.obolibrary.org/obo/UBERON_0006207 aortico-pulmonary spiral septum http://purl.obolibrary.org/obo/UBERON_0004142 outflow tract septum The spiral septum that separates the truncus arteriosus into a ventral pulmonary trunk and the dorsal aorta[MP]. The aorticopulmonary septum is developmentally formed from neural crest, specifically the cardiac neural crest, and actively separates the aorta and pulmonary arteries and fuses with the interventricular septum within the heart during development. The actual mechanism of septation of the outflow tract is poorly understood, but is recognized as a dynamic process with contributions from contractile, hemodynamic, and extracellular matrix interactions. http://purl.obolibrary.org/obo/UBERON_0006211 buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0003037 septum The thin bilaminar membrane derived from the prechordal plate that is devoid of mesoderm and formed by the apposition of the stomodeal ectoderm with the foregut endoderm; after the embryonic head fold has evolved it lies at the caudal limit of the stomodeum, forming a septum between the primitive mouth and pharynx; the membrane eventually disappears, and thus a communication is established between the mouth and the future pharynx. http://purl.obolibrary.org/obo/UBERON_0006215 rhombic lip http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The posterior section of the developing metencephalon recognized transiently within the vertebrate embryo; the rhombic lip extends posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cell and can be divided into eight structural units based on rhombomeres 1-8 (r1-r8), recognized at early stages of hindbrain development; producing granule cells and five brainstem nuclei, the rhombic lip plays an important role in developing a complex cerebellar neural system. http://purl.obolibrary.org/obo/UBERON_0006222 future diencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The foremost region of the future forebrain that develops into the diencephalon. http://purl.obolibrary.org/obo/UBERON_0006238 future brain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The embryonic precursor of the brain. http://purl.obolibrary.org/obo/UBERON_0006239 future central tendon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A tendon that has the potential to develop into a central tendon. http://purl.obolibrary.org/obo/UBERON_0006240 future forebrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a forebrain. http://purl.obolibrary.org/obo/UBERON_0006250 infundibular recess of 3rd ventricle http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac A funnel-shaped diverticulum that extends downward from the anterior aspect of the floor of the third ventricle into the infundibulum of the hypophysis; the embryonic structure gives rise the neural component of the pituitary (pas nervosa). http://purl.obolibrary.org/obo/UBERON_0006264 mouth-foregut junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junctions that overlaps the mouth and foregut. http://purl.obolibrary.org/obo/UBERON_0006267 notochordal plate http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium The notochordal plate is the dorsal part of the notochordal process when the ventral portion breaks down. It is continuous laterally with the endoderm that composes the roof of the primitive foregut and is in contact dorsally with the neural tube. The folding off of the notochordal plate gives rise to the notochord. http://purl.obolibrary.org/obo/UBERON_0006268 notochordal process http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A midline cellular cord formed from the migration of mesenchymal cells from the primitive knot. http://purl.obolibrary.org/obo/UBERON_0006279 pleuroperitoneal canal http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Each of the canals that links the peritoneal cavity and the caudal part of a pleural cavity. http://purl.obolibrary.org/obo/UBERON_0006283 future cardiac ventricle http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Multi-tissue structure that is part of the heart tube and will become the cardiac ventricle. http://purl.obolibrary.org/obo/UBERON_0006284 early prosencephalic vesicle http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle Future brain vesicle that gives rise to telencephalic ventricle/lateral ventricles and 3rd ventricle. http://purl.obolibrary.org/obo/UBERON_0006311 chamber of eyeball http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit A segment of the eyeball that is filled with refractive media. http://purl.obolibrary.org/obo/UBERON_0006312 ocular refractive media http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Body substance in a liquid or semi-solid state in the eyeball which serves to refract light. http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Liquid components of living organisms. includes fluids that are excreted or secreted from the body as well as body water that normally is not. http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A nucleus of brain that is part of a brainstem. http://purl.obolibrary.org/obo/UBERON_0006338 lateral ventricle choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma A choroid plexus stroma that is part of a lateral ventricle. http://purl.obolibrary.org/obo/UBERON_0006339 third ventricle choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma A choroid plexus stroma that is part of a third ventricle. http://purl.obolibrary.org/obo/UBERON_0006340 fourth ventricle choroid plexus stroma http://purl.obolibrary.org/obo/UBERON_0005206 choroid plexus stroma A choroid plexus stroma that is part of a fourth ventricle. http://purl.obolibrary.org/obo/UBERON_0006347 communicating artery http://purl.obolibrary.org/obo/UBERON_0001637 artery An artery that connects two larger arteries. http://purl.obolibrary.org/obo/UBERON_0006514 pallidum http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter Part of what are called the basal ganglia of the brain which consist of the globus pallidus and the ventral pallidum. http://purl.obolibrary.org/obo/UBERON_0006516 dorsal pallidum http://purl.obolibrary.org/obo/UBERON_0006514 pallidum The predominant portion of the globus pallidus in the striatopallidal system, which is defined by connectivity and neurochemical staining. The dorsal pallidum is distinguished from the ventral pallidum by a boundary that is partially defined by the anterior commissure. The remainder of the boundary is indistinct in sections stained for Nissl substance ( Heimer-1995 ). http://purl.obolibrary.org/obo/UBERON_0006535 skin secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that secreted_by a zone of skin. http://purl.obolibrary.org/obo/UBERON_0006537 female reproductive gland secretion http://purl.obolibrary.org/obo/UBERON_0022293 reproductive gland secretion A portion of organism substance that is secreted by a female reproductive gland. http://purl.obolibrary.org/obo/UBERON_0006538 respiratory system fluid/secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that secreted_by a respiratory system. http://purl.obolibrary.org/obo/UBERON_0006563 tunica media of pulmonary trunk http://purl.obolibrary.org/obo/UBERON_0007239 tunica media of artery Tunica media of artery which is continuous with the myocardium of right ventricle.[FMA]. http://purl.obolibrary.org/obo/UBERON_0006566 left ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle A myocardium that is part of a left ventricle of a heart. http://purl.obolibrary.org/obo/UBERON_0006567 right ventricle myocardium http://purl.obolibrary.org/obo/UBERON_0001083 myocardium of ventricle A myocardium that is part of a right ventricle of a heart. http://purl.obolibrary.org/obo/UBERON_0006568 hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006569 diencephalic nucleus A nucleus of brain that is part of a hypothalamus. http://purl.obolibrary.org/obo/UBERON_0006569 diencephalic nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A nucleus of brain that is part of a diencephalon. http://purl.obolibrary.org/obo/UBERON_0006595 presumptive endoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into endoderm. http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure Portion of embryonic tissue determined by fate mapping to become a structure. http://purl.obolibrary.org/obo/UBERON_0006601 presumptive ectoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into ectoderm. http://purl.obolibrary.org/obo/UBERON_0006603 presumptive mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Presumptive structure of the blastula that will develop into mesoderm. http://purl.obolibrary.org/obo/UBERON_0006606 mandibular symphysis http://purl.obolibrary.org/obo/UBERON_0002216 symphysis A cartilaginous joint that connects left and right mandibles/dentary bones. Mandibular symphysis is unpaired[TAO,modified]. http://purl.obolibrary.org/obo/UBERON_0006668 carotid canal http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull On the interior surface of the temporal bone, behind the rough surface of the apex, is the large circular aperture of the carotid canal, which ascends at first vertically, and then, making a bend, runs horizontally forward and medialward. It transmits into the cranium, the internal carotid artery, and the carotid plexus of nerves. Sympathetics to the head also pass through the carotid canal. They have several motor functions: raise the eyelid (superior tarsal muscle), dilate pupil, innervate sweat glands of face and scalp and constricts blood vessels in head[WP]. http://purl.obolibrary.org/obo/UBERON_0006670 central tendon of diaphragm http://purl.obolibrary.org/obo/UBERON_0003837 thoracic segment connective tissue The three-lobed cloverleaf-shaped aponeurosis situated at the center of the diaphragm; the central tendon is fused with the fibrous pericardium that provides attachment for the muscle fibers. http://purl.obolibrary.org/obo/UBERON_0006677 surface of epithelium http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical boundary that adjacent_to a epithelium. http://purl.obolibrary.org/obo/UBERON_0006682 hypoglossal canal http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull The hypoglossal canal is a bony canal in the occipital bone of the skull. http://purl.obolibrary.org/obo/UBERON_0006694 cerebellum vasculature http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system A vasculature that is part of a cerebellum. http://purl.obolibrary.org/obo/UBERON_0006756 median lingual swelling http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure During the third week of embryological development there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings which rise from the inner surface of the mandibular arch and meet in the middle line. The site of their meeting remains post-embryonically as the median sulcus of the tongue. The tuberculum impar is said to form the central part of the tongue immediately in front of the foramen cecum, but Hammar insists that it is purely a transitory structure and forms no part of the adult tongue[WP, Gray's]. http://purl.obolibrary.org/obo/UBERON_0006757 lateral lingual swelling http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure During the third week there appears, immediately behind the ventral ends of the two halves of the mandibular arch, a rounded swelling named the tuberculum impar, which was described by His as undergoing enlargement to form the buccal part of the tongue. More recent researches, however, show that this part of the tongue is mainly, if not entirely, developed from a pair of lateral swellings (or distal tongue bud) which rise from the inner surface of the mandibular arch and meet in the middle line. http://purl.obolibrary.org/obo/UBERON_0006761 corneo-scleral junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction The edge of the cornea where it joins the sclera; the limbus is a common site for the occurrence of corneal epithelial neoplasm. http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that is composed primarily of secretory cells. http://purl.obolibrary.org/obo/UBERON_0006815 areolar connective tissue http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue Loose connective tissue located at the outer and inner layers of organs. Examples: submucosal connective tissue, tunica adventitia of artery, papillary dermis, superficial fascia of dorsum of hand. http://purl.obolibrary.org/obo/UBERON_0006833 lumen of trachea http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a trachea. http://purl.obolibrary.org/obo/UBERON_0006834 uterus or analog http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube A subdivision of a the reproductive tract in a female organism that is the site of embryo development. http://purl.obolibrary.org/obo/UBERON_0006846 surface groove http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity A furrow or an incomplete tube. http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a organ. http://purl.obolibrary.org/obo/UBERON_0006904 head mesenchyme from mesoderm http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme A head mesenchyme that develops_from a mesoderm. http://purl.obolibrary.org/obo/UBERON_0006905 mandibular process mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a mandibular prominence. http://purl.obolibrary.org/obo/UBERON_0006909 lumen of digestive tract http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that surrounded_by a digestive tract. http://purl.obolibrary.org/obo/UBERON_0006913 lip epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a lip. http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium characterised by its most superficial layer consisting of squamous epithelial cells. http://purl.obolibrary.org/obo/UBERON_0006915 stratified squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium Multilaminar epithelium which consists of more than one layer of squamous cells only one layer of which is in contact with a basement membrane. Examples: keratinized stratified squamous epithelium, epithelium of wall of esophagus.[FMA]. http://purl.obolibrary.org/obo/UBERON_0006919 tongue squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium A squamous epithelium that is part of a tongue. http://purl.obolibrary.org/obo/UBERON_0006920 esophagus squamous epithelium http://purl.obolibrary.org/obo/UBERON_0006914 squamous epithelium A squamous epithelium that is part of a esophagus. http://purl.obolibrary.org/obo/UBERON_0006925 digestive system gland http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element Any gland that is part of the digestive system. http://purl.obolibrary.org/obo/UBERON_0006929 glandular columnar epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium Simple columnar epithelium that constitutes the secretory part of a gland. Examples: epithelium of stomach, luminal epithelium of lactiferous duct.[FMA]. http://purl.obolibrary.org/obo/UBERON_0006934 sensory epithelium http://purl.obolibrary.org/obo/UBERON_0000488 atypical epithelium Simple columnar epithelium made up of cells specialized to serve as sensory cells for the reception of external stimuli, as the sensory cells of the cochlea, vestibule, nasal mucosa, and tongue. http://purl.obolibrary.org/obo/UBERON_0006960 ovary stroma http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The stroma of the ovary is a peculiar soft tissue, abundantly supplied with blood vessels, consisting for the most part of spindle-shaped cells with a small amount of ordinary connective tissue. These cells have been regarded by some anatomists as unstriped muscle cells, which, indeed, they most resemble; by others as connective-tissue cells. On the surface of the organ this tissue is much condensed, and forms a layer composed of short connective-tissue fibers, with fusiform cells between them. The stroma of the ovary may contain interstitial cells resembling those of the testis. http://purl.obolibrary.org/obo/UBERON_0006964 pars distalis of adenohypophysis http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure The distal part of adenohypophysis: the part that makes up the main body of the gland. http://purl.obolibrary.org/obo/UBERON_0006965 vascular cord http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis[GO]. The vascular cord is composed of angioblast or vascular endothelial cells in a solid linear mass called a cord. The cord then undergoes tubulogenesis to form the lumen of the vessels[ZFA]. http://purl.obolibrary.org/obo/UBERON_0006966 coronary capillary http://purl.obolibrary.org/obo/UBERON_0003498 heart blood vessel A capillary that is part of the coronary system. http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface http://purl.obolibrary.org/obo/UBERON_0010199 bona-fide anatomical boundary A two dimensional anatomical structure that is the boundary between an anatomical structure and an anatomical substance, an anatomical space or the organism's environment. Examples include the surface of your skin, the surface of the lining of your gut; the surface of the endothelium of you aorta that is in contact with blood.n. http://purl.obolibrary.org/obo/UBERON_0007005 cardiogenic splanchnic mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The splanchnic mesoderm in the cardiogenic region where the heart develops; it gives rise to endocardial heart tubes that fuse to form the primordial cardiac tube, the heart primordium[web]. Two migratory heart primordia that move ventrally during the course of neurulation, and then fuse[XAO]. http://purl.obolibrary.org/obo/UBERON_0007010 cleaving embryo http://purl.obolibrary.org/obo/UBERON_0000922 embryo Organism at the cleavage stage. http://purl.obolibrary.org/obo/UBERON_0007098 mandibular neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest Cranial neural crest that migrates into the mandibular arch. http://purl.obolibrary.org/obo/UBERON_0007099 hyoid neural crest http://purl.obolibrary.org/obo/UBERON_0003099 cranial neural crest Cranial neural crest that migrates into the hyoid arch. http://purl.obolibrary.org/obo/UBERON_0007100 primary circulatory organ http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ A hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood or analogs[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0007122 pharyngeal pouch 1 http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch A pharyngeal pouch that is between pharyngeal arches 1 and 2. http://purl.obolibrary.org/obo/UBERON_0007123 pharyngeal pouch 2 http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch A pharyngeal puch that is between the pharyngeal arches 2 and 3. http://purl.obolibrary.org/obo/UBERON_0007124 pharyngeal pouch 3 http://purl.obolibrary.org/obo/UBERON_0004117 pharyngeal pouch A pharyngeal pouch that between pharyngeal arches 3 and 4. http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglion http://purl.obolibrary.org/obo/UBERON_0000045 ganglion Ganglion which is located in the trunk. http://purl.obolibrary.org/obo/UBERON_0007135 neural keel http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system An intermediate stage (between the neural plate and neural rod) during the early segmentation period in the morphogenesis of the central nervous system primordium; the keel is roughly triangular shaped in cross section. http://purl.obolibrary.org/obo/UBERON_0007142 left internal carotid artery http://purl.obolibrary.org/obo/UBERON_0001532 internal carotid artery An internal carotid artery that branching_part_of a left common carotid artery plus branches. http://purl.obolibrary.org/obo/UBERON_0007143 right internal carotid artery http://purl.obolibrary.org/obo/UBERON_0001532 internal carotid artery An internal carotid artery that branching_part_of a right common carotid artery plus branches. http://purl.obolibrary.org/obo/UBERON_0007188 mesothelium of serous pericardium http://purl.obolibrary.org/obo/UBERON_0003388 mesothelium of pericardial cavity A mesothelium that is part of a serous pericardium. http://purl.obolibrary.org/obo/UBERON_0007195 stroma of bone marrow http://purl.obolibrary.org/obo/UBERON_0003891 stroma The stroma of the bone marrow is all tissue not directly involved in the primary function of hematopoiesis. The yellow bone marrow belongs here, and makes the majority of the bone marrow stroma, in addition to stromal cells located in the red bone marrow. Yellow bone marrow is found in the Medullary cavity. Still, the stroma is indirectly involved in hematopoiesis, since it provides the hematopoietic microenvironment that facilitates hematopoiesis by the parenchymal cells. For instance, they generate colony stimulating factors, affecting hematopoiesis. http://purl.obolibrary.org/obo/UBERON_0007196 tracheobronchial tree http://purl.obolibrary.org/obo/UBERON_0000062 organ The structure from the trachea, bronchi, and bronchioles that forms the airways that supply air to the lungs. The lining of the tracheobronchial tree consists of ciliated columnar epithelial cells. http://purl.obolibrary.org/obo/UBERON_0007204 brachiocephalic vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The vasculature consisting of brachiocephalic arteries and veins. http://purl.obolibrary.org/obo/UBERON_0007213 mesenchyme derived from head neural crest http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that develops_from a cranial neural crest. http://purl.obolibrary.org/obo/UBERON_0007214 mesenchyme derived from trunk neural crest http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme Mesenchyme that develops_from a trunk neural crest. http://purl.obolibrary.org/obo/UBERON_0007239 tunica media of artery http://purl.obolibrary.org/obo/UBERON_0002522 tunica media A tunica media that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0007240 tunica adventitia of artery http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel A tunica adventitia that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0007241 tunica adventitia of vein http://purl.obolibrary.org/obo/UBERON_0005734 tunica adventitia of blood vessel A tunica adventitia that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0007242 tunica intima of vein http://purl.obolibrary.org/obo/UBERON_0004797 blood vessel layer A tunica intima that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0007243 tunica media of vein http://purl.obolibrary.org/obo/UBERON_0002522 tunica media A tunica media that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis http://purl.obolibrary.org/obo/UBERON_0002020 gray matter Gray matter of the central nervous system which is a collection of clustered nuclei. http://purl.obolibrary.org/obo/UBERON_0007247 nucleus of superior olivary complex http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus Any of the nuclei that comprise the superior olivary complex (superior olive). This includes both the primary nuclei such as the lateral and medial nuclei, as well as periolivary nuclei. http://purl.obolibrary.org/obo/UBERON_0007267 trachea pre-cartilage rings http://purl.obolibrary.org/obo/UBERON_0009505 mesenchyme of trachea A pre-cartilage condensation that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0007269 pectoral appendage musculature http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex Any collection of muscles that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007271 appendage musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of an appendage. http://purl.obolibrary.org/obo/UBERON_0007272 pectoral appendage skeleton http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton Skeletal subdivision consisting of the anterior appendicular limb skeleton, excluding the pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0007277 presumptive hindbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The rhombencephalon (or hindbrain) is a developmental categorization of portions of the central nervous system in vertebrates. The rhombencephalon can be subdivided in a variable number of transversal swellings called rhombomeres. In the human embryo eight rhombomeres can be distinguished, from caudal to rostral: Rh7-Rh1 and the isthmus (the most rostral rhombomere). A rare disease of the rhombencephalon, 'rhombencephalosynapsis' is characterized by a missing vermis resulting in a fused cerebellum. Patients generally present with cerebellar ataxia. The caudal rhombencephalon has been generally considered as the initiation site for neural tube closure. http://purl.obolibrary.org/obo/UBERON_0007278 presumptive sinus venosus http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is part of the heart tube and will become the sinus venosus. http://purl.obolibrary.org/obo/UBERON_0007280 presumptive endocardium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a endocardium. http://purl.obolibrary.org/obo/UBERON_0007281 presumptive midbrain hindbrain boundary http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that gives rise to the midbrain hindbrain boundary. http://purl.obolibrary.org/obo/UBERON_0007282 presumptive segmental plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0007284 presumptive neural plate http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system A presumptive structure that has the potential to develop into a neural plate. http://purl.obolibrary.org/obo/UBERON_0007285 presumptive paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The part of the blastula that has the potential to develop into a paraxial mesoderm. http://purl.obolibrary.org/obo/UBERON_0007286 presumptive floor plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a floor plate. http://purl.obolibrary.org/obo/UBERON_0007288 presumptive forebrain midbrain boundary http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a forebrain-midbrain boundary. http://purl.obolibrary.org/obo/UBERON_0007289 presumptive rhombomere 1 http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a rhombomere 1. http://purl.obolibrary.org/obo/UBERON_0007300 pectoral appendage blood vessel http://purl.obolibrary.org/obo/UBERON_0007301 appendage blood vessel A blood vessel that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007301 appendage blood vessel http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel A blood vessel that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0007302 pectoral appendage vasculature http://purl.obolibrary.org/obo/UBERON_0007304 appendage vasculature A vasculature that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007303 pharyngeal vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ A vasculature that is part of a chordate pharynx. http://purl.obolibrary.org/obo/UBERON_0007304 appendage vasculature http://purl.obolibrary.org/obo/UBERON_0002049 vasculature A vasculature that is part of a limb/fin. http://purl.obolibrary.org/obo/UBERON_0007367 surface of tongue http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical surface that is part of a tongue. http://purl.obolibrary.org/obo/UBERON_0007373 inferior surface of tongue http://purl.obolibrary.org/obo/UBERON_0007367 surface of tongue The lower (inferior) side of the tongue. http://purl.obolibrary.org/obo/UBERON_0007376 outer epithelium http://purl.obolibrary.org/obo/UBERON_0003102 surface structure The epidermis is the entire outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species[GO]. http://purl.obolibrary.org/obo/UBERON_0007383 enveloping layer of ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Outermost layer of cells surrounding the embryo. http://purl.obolibrary.org/obo/UBERON_0007389 paired limb/fin cartilage http://purl.obolibrary.org/obo/UBERON_0002418 cartilage tissue A cartilage tissue that is part of a paired limb or fin. http://purl.obolibrary.org/obo/UBERON_0007390 pectoral appendage cartilage tissue http://purl.obolibrary.org/obo/UBERON_0007389 paired limb/fin cartilage A cartilage tissue that is part of a pectoral appendage. http://purl.obolibrary.org/obo/UBERON_0007414 nucleus of midbrain tegmentum http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A nucleus of brain that spans a midbrain tegmentum. http://purl.obolibrary.org/obo/UBERON_0007473 lumen of epithelial sac http://purl.obolibrary.org/obo/UBERON_0012467 enclosed anatomical space The space within an epithelial sphere. http://purl.obolibrary.org/obo/UBERON_0007475 matrix-based tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue A tissue whose predominant feature is extracellular matrix which may or may not be highly hydrated or calcified. http://purl.obolibrary.org/obo/UBERON_0007499 epithelial sac http://purl.obolibrary.org/obo/UBERON_0009856 sac An epithelial tube that is open at one end only. http://purl.obolibrary.org/obo/UBERON_0007500 epithelial tube open at both ends http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube An epithelial tube open at both ends that allows fluid flow. http://purl.obolibrary.org/obo/UBERON_0007503 epithelial vesicle http://purl.obolibrary.org/obo/UBERON_0000483 epithelium A closed epithelium with a lumen. http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme with little extracellular matrix. http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchymal cells that are migrating. http://purl.obolibrary.org/obo/UBERON_0007592 ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium Simple columnar epithelium in which the luminal side of the cells bears cilia. Examples: epithelium of trachea, epithelium of uterine tube.[FMA]. http://purl.obolibrary.org/obo/UBERON_0007601 ciliated epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium bearing vibratile cilia on the free surface. http://purl.obolibrary.org/obo/UBERON_0007617 synovial cavity of joint http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity An anatomical cavity that surrounded_by a synovial joint. http://purl.obolibrary.org/obo/UBERON_0007625 pigment epithelium of eye http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium Epithelial layer of the retina, ciliary body, or iris composed of cells containing pigment granules. http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus A neural nucleus that is part of a medulla oblongata. http://purl.obolibrary.org/obo/UBERON_0007641 trigeminal nuclear complex http://purl.obolibrary.org/obo/UBERON_0007245 nuclear complex of neuraxis The sensory trigeminal nerve nuclei are the largest of the cranial nerve nuclei, and extend through the whole of the midbrain, pons and medulla. There is also a distinct trigeminal motor nucleus that is medial to the chief sensory nucleus[WP]. http://purl.obolibrary.org/obo/UBERON_0007645 future meninx http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing mesenchymal capsule that covers the developing brain and spinal cord and is the precursor of the meningeal cluster. In mammals this gives rise to the arachnoid mater, pia mater and dura mater. In cyclostomes and fishes, the future meninx gives rise to a single meningeal layer, the primitive meninx. http://purl.obolibrary.org/obo/UBERON_0007646 endomeninx http://purl.obolibrary.org/obo/UBERON_0007645 future meninx The innermost layer of the mesenchymal capsule that surrounds the developing brain, primarily of neural crest origin. The endomeninx forms the leptomeninx. http://purl.obolibrary.org/obo/UBERON_0007647 ectomeninx http://purl.obolibrary.org/obo/UBERON_0007645 future meninx The outermost layer of the mesenchymal capsule that surrounds the developing brain, of mixed paraxial mesoderm and neural crest origin. The ectomeninx forms the dura mater (both inner layer and outer chondrogenic layer). http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that connects two structures. http://purl.obolibrary.org/obo/UBERON_0007688 anlage http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Anlagen are populations of contiguous cells, typically arranged in one plane, that are morphologically indistinct, but that already correspond in extent to a later organ/tissue. http://purl.obolibrary.org/obo/UBERON_0007691 gustatory pore http://purl.obolibrary.org/obo/UBERON_0000161 orifice The minute opening of a taste bud on the surface of the oral mucosa through which the gustatory hairs of the specialised neuroepithelial gustatory cells project. http://purl.obolibrary.org/obo/UBERON_0007692 nucleus of thalamus http://purl.obolibrary.org/obo/UBERON_0006569 diencephalic nucleus A nucleus of brain that is part of a thalamus. http://purl.obolibrary.org/obo/UBERON_0007719 bone of reproductive organ http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A bone that is part of a reproductive organ. http://purl.obolibrary.org/obo/UBERON_0007771 epidermis gland http://purl.obolibrary.org/obo/UBERON_0002419 skin gland A gland that is part of a epidermis. http://purl.obolibrary.org/obo/UBERON_0007779 transudate http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Any bodily fluid that has passed through a membrane such as the capillary wall, as a result of unbalanced hydrostatic and osmotic forces. http://purl.obolibrary.org/obo/UBERON_0007794 secretion of serous gland http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Any fluid produced by a serous gland. http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region http://purl.obolibrary.org/obo/UBERON_0003567 abdomen connective tissue Adipose tissue that is located in the abdominal region. This includes any subcutaneous fat, visceral fat or encapsulated adipose tissue depots. http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The anteriormost subdivision of the body that includes the head, jaws, pharyngeal region and the neck (if present). In vertebrates this is the subdivision that includes the cervical vertebrae. http://purl.obolibrary.org/obo/UBERON_0007823 appendage girdle region http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision An organism subdivision that encompasses the region containing the pectoral or pelvic girdle. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0007828 girdle bone/zone http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a appendage girdle region. http://purl.obolibrary.org/obo/UBERON_0007829 pectoral girdle bone http://purl.obolibrary.org/obo/UBERON_0010741 bone of pectoral complex A bone that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/UBERON_0007842 membrane bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element Bone element that arises as a result of intramembranous ossification. http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that is composed of cartilage tissue and may be permanent or transient. http://purl.obolibrary.org/obo/UBERON_0007845 regular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of fibroblasts, the intercellular matrix of which contains a regular network of collagen and elastic fiber bundles. Examples: bone (tissue), cartilage (tissue), dense regular connective tissue. http://purl.obolibrary.org/obo/UBERON_0007846 dense regular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Connective tissue that is dominated by collagen fibres organized into a definitive pattern (e.g., parallel to one another), with comparatively fewer cells (mostly fibroblasts). http://purl.obolibrary.org/obo/UBERON_0007914 bone of craniocervical region http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0008001 irregular bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element The irregular bones are bones which, from their peculiar form, cannot be grouped as long bone, short bone, flat bone or sesamoid bone. Irregular bones serve various purposes in the body, such as protection of nervous tissue, affording multiple anchor points for skeletal muscle attachment (as with the sacrum), and maintaining pharynx and trachea support, and tongue attachment (such as the hyoid bone). They consist of cancellous tissue enclosed within a thin layer of compact bone. The irregular bones are: the vertebrC&, sacrum, coccyx, temporal, sphenoid, ethmoid, zygomatic, maxilla, mandible, palatine, inferior nasal concha, and hyoid. http://purl.obolibrary.org/obo/UBERON_0008114 joint of girdle http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint A skeletal joint that is part of a appendage girdle region. http://purl.obolibrary.org/obo/UBERON_0008115 surface of cartilage http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region An anatomical surface that is part of a cartilage element. http://purl.obolibrary.org/obo/UBERON_0008193 pneumatized bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is hollow or contains many air cells, such as the mastoid process of the temporal bone[TMD]. http://purl.obolibrary.org/obo/UBERON_0008196 muscle of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle Any muscle organ that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/UBERON_0008229 craniocervical region musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Musculature system of the pharyngeal and head regions. http://purl.obolibrary.org/obo/UBERON_0008231 dorsal thoracic segment of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision Subdivision of thorax, which in humans is the posterior part of the thorax and is demarcated from the chest by the external surface of the posterolateral part of the rib cage and the anterior surface of the thoracic vertebral column; together with the chest, it constitutes the thorax. http://purl.obolibrary.org/obo/UBERON_0008243 upper back muscle http://purl.obolibrary.org/obo/UBERON_0003830 thoracic segment muscle A muscle of back that is part of a dorsal thoracic segment of trunk. http://purl.obolibrary.org/obo/UBERON_0008307 heart endothelium http://purl.obolibrary.org/obo/UBERON_0004852 cardiovascular system endothelium An endothelium that is part of a heart [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0008397 tracheobronchial epithelium http://purl.obolibrary.org/obo/UBERON_0004815 lower respiratory tract epithelium Epithelium pertaining to the trachea and bronchi. http://purl.obolibrary.org/obo/UBERON_0008780 inner cell mass derived epiblast http://purl.obolibrary.org/obo/UBERON_0002532 epiblast (generic) An embryonic structure that is derived from the inner cell mass and lies above the hypoblast and gives rise to the three primary germ layers. http://purl.obolibrary.org/obo/UBERON_0008814 pharyngeal arch system http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure A transient embryonic complex that comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming, which may include (depending on species) the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear[GO,modified]. http://purl.obolibrary.org/obo/UBERON_0008816 embryonic head http://purl.obolibrary.org/obo/UBERON_0000033 head A head that is part of a embryo. http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain http://purl.obolibrary.org/obo/UBERON_0000489 cavitated compound organ A brain that develops_from a neural tube. http://purl.obolibrary.org/obo/UBERON_0008851 ectoplacental cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space Closed space within the ectoplacental cone, formed by the fusion of the parts of the amniotic fold that separate it from the amniotic cavity[MP]. a developmental cavity that exists in some mammals and is derived by division of the proamniotic space; it is further removed from the embryo than the amniotic cavity in some mammals. http://purl.obolibrary.org/obo/UBERON_0008876 hypodermis skeletal muscle layer http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any skeletal muscle organ in the hypodermis / superficial fascia. http://purl.obolibrary.org/obo/UBERON_0008884 left putamen http://purl.obolibrary.org/obo/UBERON_0001874 putamen A putamen that is part of a left cerebral hemisphere. http://purl.obolibrary.org/obo/UBERON_0008885 right putamen http://purl.obolibrary.org/obo/UBERON_0001874 putamen A putamen that is part of a right cerebral hemisphere. http://purl.obolibrary.org/obo/UBERON_0008886 pulmonary vascular system http://purl.obolibrary.org/obo/UBERON_0007798 vascular system The part of the cardiovascular system consisting of all pulmonary arteries and all pulmonary veins. http://purl.obolibrary.org/obo/UBERON_0008895 splanchnocranium http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system Subdivision of endoskeleton derived from pharyngeal arches. http://purl.obolibrary.org/obo/UBERON_0008896 post-hyoid pharyngeal arch http://purl.obolibrary.org/obo/UBERON_0002539 pharyngeal arch A pharyngeal arch that is posterior to the hyoid arch. i.e. any pharyngeal arch with a number 3 or higher. http://purl.obolibrary.org/obo/UBERON_0008907 dermal bone http://purl.obolibrary.org/obo/UBERON_0007842 membrane bone Skeletal element that forms superficially in the organism, usually in association with the ectoderm[VSAO]. http://purl.obolibrary.org/obo/UBERON_0008909 perichordal bone http://purl.obolibrary.org/obo/UBERON_0012075 replacement bone Bone element that is adjacent to the notochord. http://purl.obolibrary.org/obo/UBERON_0008946 lung parenchyma http://purl.obolibrary.org/obo/UBERON_0000353 parenchyma A parenchyma that is part of a lung. http://purl.obolibrary.org/obo/UBERON_0008998 vasculature of brain http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system System pertaining to blood vessels in the brain. http://purl.obolibrary.org/obo/UBERON_0009015 upper back skin http://purl.obolibrary.org/obo/UBERON_0001418 skin of thorax A zone of skin that is part of a dorsal thoracic segment of trunk. http://purl.obolibrary.org/obo/UBERON_0009030 left pulmonary vein http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein Vein that drains left lung and returns blood to the heart. http://purl.obolibrary.org/obo/UBERON_0009032 right pulmonary vein http://purl.obolibrary.org/obo/UBERON_0002016 pulmonary vein Vein that drains right lung and returns blood to the heart. http://purl.obolibrary.org/obo/UBERON_0009117 indifferent gonad http://purl.obolibrary.org/obo/UBERON_0000991 gonad A gonad prior to differentiating into a definitive testis or ovary. http://purl.obolibrary.org/obo/UBERON_0009122 adenohypophyseal placode http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode The adenohypophyseal placode forms the anterior lobe of the pituitary gland and gives rise to the endocrine secretory cells of the pituitary. http://purl.obolibrary.org/obo/UBERON_0009125 petrosal placode http://purl.obolibrary.org/obo/UBERON_0003078 epibranchial placode Epibranchial placode between geniculate and nodose. Associated with 2nd branchial cleft. http://purl.obolibrary.org/obo/UBERON_0009127 epibranchial ganglion http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Cranial ganglion which develops from an epibranchial placode. http://purl.obolibrary.org/obo/UBERON_0009129 right atrium endocardium http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium Endocardium that is part of the right atrium. http://purl.obolibrary.org/obo/UBERON_0009133 pleuroperitoneal membrane http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue A fold of tissue which extends into the peritoneal cavity of the developing embryo and participates in the separation of the pleural and peritoneal cavities. http://purl.obolibrary.org/obo/UBERON_0009141 craniocervical region vein http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein A vein that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0009142 entire embryonic mesenchyme http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster Sum total of mesenchyme in the embryo. http://purl.obolibrary.org/obo/UBERON_0009198 craniofacial suture http://purl.obolibrary.org/obo/UBERON_0002209 fibrous joint Any suture between cranial and/or facial bones. http://purl.obolibrary.org/obo/UBERON_0009199 facial suture http://purl.obolibrary.org/obo/UBERON_0009198 craniofacial suture Any suture between facial bones. http://purl.obolibrary.org/obo/UBERON_0009471 dorsum of tongue http://purl.obolibrary.org/obo/UBERON_0000064 organ part The superior surface of the tongue divided by the sulcus terminalis into an anterior two-thirds, the presulcal part (pars presulcalis). and a posterior one-third, the postsulcal part (pars postsulcalis). http://purl.obolibrary.org/obo/UBERON_0009479 ectoderm of buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0000924 ectoderm An ectoderm that is part of a buccopharyngeal membrane. http://purl.obolibrary.org/obo/UBERON_0009480 endoderm of buccopharyngeal membrane http://purl.obolibrary.org/obo/UBERON_0000925 endoderm An endoderm that is part of a buccopharyngeal membrane. http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue A portion of mesenchymal tissue associated with an individual pharyngeal arch. http://purl.obolibrary.org/obo/UBERON_0009505 mesenchyme of trachea http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that is part of a developing trachea. http://purl.obolibrary.org/obo/UBERON_0009522 lateral lingual swelling epithelium http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue An epithelium that is part of a lateral lingual swelling. http://purl.obolibrary.org/obo/UBERON_0009536 vascular element of left lung http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus A vascular plexus that is part of a left lung. http://purl.obolibrary.org/obo/UBERON_0009537 vascular element of right lung http://purl.obolibrary.org/obo/UBERON_0005629 vascular plexus A vascular plexus that is part of a right lung. http://purl.obolibrary.org/obo/UBERON_0009570 spinal cord sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future spinal cord. http://purl.obolibrary.org/obo/UBERON_0009571 ventral midline http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. http://purl.obolibrary.org/obo/UBERON_0009572 lumen of central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space A cerebrospinal fluid-filled space that runs longitudinally through the length of the entire spinal cord. The central canal is contiguous with the ventricular system of the brain. The central canal represents the adult remainder of the neural tube. http://purl.obolibrary.org/obo/UBERON_0009576 medulla oblongata sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future medulla oblongata. http://purl.obolibrary.org/obo/UBERON_0009577 metencephalon sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future metencephalon. http://purl.obolibrary.org/obo/UBERON_0009578 myelencephalon sulcus limitans http://purl.obolibrary.org/obo/UBERON_0005478 sulcus limitans of neural tube A sulcus limitans of neural tube that is part of a future myelencephalon. http://purl.obolibrary.org/obo/UBERON_0009584 1st arch mandibular mesenchyme http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme Mesenchyme that is part of a 1st arch mandibular component. http://purl.obolibrary.org/obo/UBERON_0009602 left lung associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme Mesenchyme that is part of a developing left lung. http://purl.obolibrary.org/obo/UBERON_0009603 right lung associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0004883 lung mesenchyme Mesenchyme that is part of a developing right lung. http://purl.obolibrary.org/obo/UBERON_0009610 forebrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a future forebrain. http://purl.obolibrary.org/obo/UBERON_0009611 midbrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a presumptive midbrain. http://purl.obolibrary.org/obo/UBERON_0009614 hindbrain neural plate http://purl.obolibrary.org/obo/UBERON_0003075 neural plate A neural plate that develops_from a presumptive hindbrain. http://purl.obolibrary.org/obo/UBERON_0009616 presumptive midbrain http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A presumptive structure that has the potential to develop into a midbrain. http://purl.obolibrary.org/obo/UBERON_0009617 head paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Bilateral mesenchymal mesoderm parallel and immediately adjacent to the neural tube/notochord; it generates a subset of extra-ocular, and other head, muscles. http://purl.obolibrary.org/obo/UBERON_0009652 bronchus basement membrane http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane A basement membrane that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0009653 trachea basement membrane http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane A basement membrane that is part of a trachea. http://purl.obolibrary.org/obo/UBERON_0009661 midbrain nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus located in the midbrain. http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain Nucleus located within the hindbrain. http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus http://purl.obolibrary.org/obo/UBERON_0002308 nucleus of brain A nucleus of brain that is part of a telencephalon. http://purl.obolibrary.org/obo/UBERON_0009712 endocardium of right ventricle http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle Any endocardium that is part of the right ventricle of the heart. http://purl.obolibrary.org/obo/UBERON_0009713 endocardium of left ventricle http://purl.obolibrary.org/obo/UBERON_0001081 endocardium of ventricle Any endocardium that is part of the left ventricle of the heart. http://purl.obolibrary.org/obo/UBERON_0009715 stomodeal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a stomodeum. http://purl.obolibrary.org/obo/UBERON_0009751 cardiac mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme The embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing cardiac structures. http://purl.obolibrary.org/obo/UBERON_0009758 abdominal ganglion http://purl.obolibrary.org/obo/UBERON_0007134 trunk ganglion A ganglion that is part of a abdominal segment of trunk. http://purl.obolibrary.org/obo/UBERON_0009778 pleural sac http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A serous sac that has the pleura and the pleural cavity as parts. http://purl.obolibrary.org/obo/UBERON_0009841 upper rhombic lip http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Anterior-most region of dorsal hindbrain within rhombomere 1, adjacent the midbrain-hindbrain boundary. http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster The many-lobed berry cluster of cells that is the terminous of a gland where the secretion is produced is acinar in form. http://purl.obolibrary.org/obo/UBERON_0009854 digestive tract diverticulum http://purl.obolibrary.org/obo/UBERON_0009856 sac Branch or outpocketing of the digestive tract. http://purl.obolibrary.org/obo/UBERON_0009889 secondary heart field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the lateral mesoderm that will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract). http://purl.obolibrary.org/obo/UBERON_0009891 facial mesenchyme http://purl.obolibrary.org/obo/UBERON_0005253 head mesenchyme Mesenchyme that is part of a developing face. http://purl.obolibrary.org/obo/UBERON_0009953 post-embryonic organism http://purl.obolibrary.org/obo/UBERON_0000468 multicellular organism A multicellular organism that existence_starts_with a post-embryonic stage. http://purl.obolibrary.org/obo/UBERON_0009955 neurogenic placode http://purl.obolibrary.org/obo/UBERON_0002546 cranial placode Cranial ectodermal placode with potential to develop into a component of the nervous system, such as nerves or ganglia. http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has more than one cell as a part. http://purl.obolibrary.org/obo/UBERON_0010009 aggregate regional part of brain http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group A regional part of brain consisting of multiple brain regions that are not related through a simple volummetric part of hierarchy, e.g., basal ganglia[NIF]. http://purl.obolibrary.org/obo/UBERON_0010031 6th arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 6. http://purl.obolibrary.org/obo/UBERON_0010032 anterior part of tongue http://purl.obolibrary.org/obo/UBERON_0000064 organ part The portion of the tongue in front of the terminal sulcus. At the apex, thin and narrow, it is directed forward against the lingual surfaces of the lower incisor teeth. It is derived primarily from the first pharyngeal arch. http://purl.obolibrary.org/obo/UBERON_0010042 1st arch mesenchyme http://purl.obolibrary.org/obo/UBERON_0009494 pharyngeal arch mesenchymal region Mesenchyme that is part of a pharyngeal arch 1. http://purl.obolibrary.org/obo/UBERON_0010046 entire pharyngeal arch associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue The sum total of mesenchymal tissue in the pharyngeal arch region. Pharyngeal mesenchyme is undifferentiated, loose connective tissue derived mostly from mesoderm, and also contains ectodermally derived neural crest cells. http://purl.obolibrary.org/obo/UBERON_0010047 oral gland http://purl.obolibrary.org/obo/UBERON_0003408 gland of digestive tract Gland of the epithelium lining the oral cavity. The most common are the salivary glands. http://purl.obolibrary.org/obo/UBERON_0010052 mucosa of dorsum of tongue http://purl.obolibrary.org/obo/UBERON_0005020 mucosa of tongue A mucosa that is part of a dorsum of tongue. http://purl.obolibrary.org/obo/UBERON_0010056 future tongue http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A compound organ that has the potential to develop into a tongue. http://purl.obolibrary.org/obo/UBERON_0010075 sacral neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue One of the 5 distinct and partially overlapping functional domains of the premigratory neural crest. The vagal and sacral neural crest cells develop into the ganglia of the enteric nervous system, also known as the parasympathetic ganglia. http://purl.obolibrary.org/obo/UBERON_0010077 cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium consisting of cuboidal epithelial cells. http://purl.obolibrary.org/obo/UBERON_0010083 future dermis http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that has the potential to develop into a dermis. http://purl.obolibrary.org/obo/UBERON_0010084 future diaphragm http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A structure that will develop into a diaphragm. http://purl.obolibrary.org/obo/UBERON_0010091 future hindbrain meninx http://purl.obolibrary.org/obo/UBERON_0007645 future meninx A multi-tissue structure that has the potential to develop into a meninx of hindbrain. http://purl.obolibrary.org/obo/UBERON_0010092 future metencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a metencephalon. http://purl.obolibrary.org/obo/UBERON_0010096 future myelencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure A developing anatomical structure that has the potential to develop into a myelencephalon. http://purl.obolibrary.org/obo/UBERON_0010125 future superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002020 gray matter A gray matter that has the potential to develop into a superior salivatory nucleus. http://purl.obolibrary.org/obo/UBERON_0010131 conducting tissue of heart http://purl.obolibrary.org/obo/UBERON_0001133 cardiac muscle tissue Any portion of cardiac muscle tissue that is part of the conducting system of heart or the Purkinje fibers. http://purl.obolibrary.org/obo/UBERON_0010133 neuroendocrine gland http://purl.obolibrary.org/obo/UBERON_0002368 endocrine gland Any of the organized aggregations of cells that function as secretory or excretory organs and that release hormones in response to neural stimuli. http://purl.obolibrary.org/obo/UBERON_0010134 secretory circumventricular organ http://purl.obolibrary.org/obo/UBERON_0010133 neuroendocrine gland A circumventricular organ that is capable of secreting substances into the cerebrospinal fluid. http://purl.obolibrary.org/obo/UBERON_0010135 sensory circumventricular organ http://purl.obolibrary.org/obo/UBERON_0005408 circumventricular organ A circumventricular organ that is capable of monitoring the levels of substances to the cerebrospinal fluid. http://purl.obolibrary.org/obo/UBERON_0010136 epithelial sheet http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelial sheet is a flat surface consisting of closely packed epithelial cells. http://purl.obolibrary.org/obo/UBERON_0010161 lumen of blood vessel http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that surrounded_by a blood vessel. http://purl.obolibrary.org/obo/UBERON_0010188 protuberance http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ A roughly circular bulge in a surface. http://purl.obolibrary.org/obo/UBERON_0010192 genital artery http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery One of the laterally paired arteries that supply the gonads. http://purl.obolibrary.org/obo/UBERON_0010199 bona-fide anatomical boundary http://purl.obolibrary.org/obo/UBERON_0000466 immaterial anatomical entity An anatomical boundary that corresponds to some physical discontinuity. http://purl.obolibrary.org/obo/UBERON_0010212 laryngeal apparatus http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure Apparatus located between the lungs and the buccal cavity. This apparatus is composed of a pair of arytenoid cartilages that are supported by the cricoid ring. http://purl.obolibrary.org/obo/UBERON_0010225 thalamic complex http://purl.obolibrary.org/obo/UBERON_0019269 gray matter of diencephalon A nuclear complex which in mammals consists of four parts, the hypothalamus, epithalamus, ventral thalamus, and dorsal thalamus[WP,modified]. http://purl.obolibrary.org/obo/UBERON_0010227 future cardiac atrium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Multi-tissue structure that is part of the heart tube and will become the cardiac atrium. http://purl.obolibrary.org/obo/UBERON_0010230 eyeball of camera-type eye http://purl.obolibrary.org/obo/UBERON_0000020 sense organ The core globe-shaped component of the camera-type eye. http://purl.obolibrary.org/obo/UBERON_0010243 merocrine gland http://purl.obolibrary.org/obo/UBERON_0002365 exocrine gland An exocrine gland whose secretions are excreted via exocytosis from secretory cells into an epithelial-walled duct or ducts and thence onto a bodily surface or into the lumen; the gland releases its product and no part of the gland is lost or damaged. http://purl.obolibrary.org/obo/UBERON_0010252 1st arch mandibular mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mandibular mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010254 2nd arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 2nd arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010255 3rd arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 3rd arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010256 4th arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 4th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010257 6th arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 6th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Mesenchyme that develops_from a rhombencephalon neural crest. http://purl.obolibrary.org/obo/UBERON_0010259 1st arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest Mesenchyme that develops_from a neural crest and is part of a 1st arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010272 hyoid apparatus http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system A group of bones comprised of hyoid body and two pairs of cornua (i.e. greater cornua and lesser cornua), and lies just below the tongue, above the thyroid cartilage. http://purl.obolibrary.org/obo/UBERON_0010285 midbrain basal plate http://purl.obolibrary.org/obo/UBERON_0002020 gray matter Portion of tissue that is dorsolateral to the floor plate and part of the midbrain. http://purl.obolibrary.org/obo/UBERON_0010286 midbrain neural tube http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Portion of neural tube that gives rise to the midbrain. http://purl.obolibrary.org/obo/UBERON_0010294 scleral endothelium http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium An endothelium that is part of a sclera. http://purl.obolibrary.org/obo/UBERON_0010295 substantia propria of sclera http://purl.obolibrary.org/obo/UBERON_0010291 layer of sclera A stroma that is part of a sclera. http://purl.obolibrary.org/obo/UBERON_0010299 scleral mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme surrounding the developing optic cup which develops into the sclera. http://purl.obolibrary.org/obo/UBERON_0010303 extraembryonic epithelium http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue An epithelium that is part of a extraembryonic structure. http://purl.obolibrary.org/obo/UBERON_0010312 immature eye http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure Developing anatomical structure that develops into the eyeball and associated structures. http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest An anatomical structure that develops from the neural crest. http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure An anatomical structure that has some part that develops from the neural crest. http://purl.obolibrary.org/obo/UBERON_0010321 skeletal element of eye region http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure A skeletal element that is part of a orbital region. http://purl.obolibrary.org/obo/UBERON_0010323 cranial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Skeletal subdivision of the head including skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. http://purl.obolibrary.org/obo/UBERON_0010329 paired limb/fin bud mesenchyme http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure Mesenchyme that is part of a limb/fin bud. http://purl.obolibrary.org/obo/UBERON_0010333 extraembryonic membrane mesenchyme http://purl.obolibrary.org/obo/UBERON_0005292 extraembryonic tissue Mesenchyme that is part of a extraembryonic membrane. http://purl.obolibrary.org/obo/UBERON_0010336 mandibular process mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0010258 mesenchyme from rhombencephalic neural crest Mesenchyme that develops_from a neural crest and is part of a mandibular process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010337 mandibular process mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0006905 mandibular process mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a mandibular process mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010339 1st arch mandibular mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mandibular mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010341 1st arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 1st arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010343 2nd arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 2nd arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010344 3rd arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 3rd arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010345 4th arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 4th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010347 6th arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a 6th arch mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010359 pharyngeal arch mesenchyme from neural crest http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest Mesenchyme that develops_from a neural crest and is part of a entire pharyngeal arch associated mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010360 pharyngeal arch mesenchyme from head mesenchyme http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue Mesenchyme that develops_from a head mesenchyme from mesoderm and is part of a entire pharyngeal arch associated mesenchyme. http://purl.obolibrary.org/obo/UBERON_0010362 endoskeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that undergoes indirect development and includes elements that develop as a replacement or substitution of other elements or tissues. http://purl.obolibrary.org/obo/UBERON_0010363 endochondral element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element A skeletal element that has the potential to participate in endochondral ossification, and may participate in intramembranous ossification. http://purl.obolibrary.org/obo/UBERON_0010364 dermal skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Skeletal subdivision that undergoes direct development and includes elements that either develop in association with the basement membrane of the ectoderm or are homologous with such elements; includes dermatocranium, components of the appendicular skeleton, teeth and tooth-like elements of the oropharynx, and integumentary elements. http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure Epithelium composed of cells that develops from the ectoderm[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0010377 mesenchyme from somatopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a somatopleure. http://purl.obolibrary.org/obo/UBERON_0010378 mesenchyme from splanchnopleure http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue Mesenchyme that develops_from a splanchnopleure. http://purl.obolibrary.org/obo/UBERON_0010409 ocular surface region http://purl.obolibrary.org/obo/UBERON_0000063 organ subunit The integrated unit (of the eye) that consists of the conjunctiva, the corneal surface, and the ocular mucosal adnexa including the lid margins and the meibomian gland openings, the lacrimal glands and the lacrimal drainage system, all which are critical to maintain ocular surface integrity and provide protection from external antigens and pathogenic microorganisms. http://purl.obolibrary.org/obo/UBERON_0010427 ciliary processes http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The ciliary processes are formed by the inward folding of the various layers of the choroid, i.e. , the choroid proper and the lamina basalis, and are received between corresponding foldings of the suspensory ligament of the lens. http://purl.obolibrary.org/obo/UBERON_0010428 flat bone http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is shaped as a broad flat plate and composed of two thin layers of compact tissue enclosing between them a variable quantity of cancellous tissue, which is the location of red bone marrow. http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000485 simple columnar epithelium A simple columnar epithelium that looks stratified but is not, because its cells are arranged with their nuclei at different levels. http://purl.obolibrary.org/obo/UBERON_0010499 pseudostratified ciliated columnar epithelium http://purl.obolibrary.org/obo/UBERON_0010498 pseudostratified columnar epithelium Epithelium composed of a single layer of cells, appearing as layered because the column-shaped cells vary in height so the nuclei are at different levels. The basal portions of all the cells are in contact with the basement membrane. It lines the respiratory system and the male reproductive tract. The cilia in the respiratory tract are motile, while the stereocilia in the male reproductive tract are immobile. http://purl.obolibrary.org/obo/UBERON_0010522 replacement element http://purl.obolibrary.org/obo/UBERON_0004765 skeletal element Skeletal element that forms as a replacement or substitution of another element or tissue. http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel http://purl.obolibrary.org/obo/UBERON_0000055 vessel A vessel of the microcirculature, lying between the arterioles and venules; includes capillaries (blood and lymphatic), metarterioles and arteriovenous anastomoses. http://purl.obolibrary.org/obo/UBERON_0010527 cavity of bone organ http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity An organ cavity that surrounded_by a bone. http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure An organism subdivision that includes both an appendage and its associated girdle region. Note that this includes both the skeletal elements and associated tissues (integument, muscle, etc). http://purl.obolibrary.org/obo/UBERON_0010708 pectoral complex http://purl.obolibrary.org/obo/UBERON_0010707 appendage girdle complex Appendage girdle complex that when present, encompasses the pectoral appendicular skeleton and the pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The subdivision of the skeleton of either the pectoral or pelvic girdle. http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex http://purl.obolibrary.org/obo/UBERON_0001474 bone element A bone that is part of an appendage girdle complex (i.e. any bone in a limb, fin or girdle). http://purl.obolibrary.org/obo/UBERON_0010741 bone of pectoral complex http://purl.obolibrary.org/obo/UBERON_0010740 bone of appendage girdle complex A bone that is part of a pectoral complex. Examples: scapula, manus phalanx, any carpal bone, any bone of the pectoral fin. http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate A muscle of a pectoral girdle, pectoral fin or anterior limb. http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision Anatomical cluster consisting of the skeletal elements (i.e. bone elements, cartilage elements, cartilage condensations) that are part of an individual subdivision of the organism. Excludes joints. http://purl.obolibrary.org/obo/UBERON_0010959 craniocervical muscle http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate Any muscle organ that is part of either the head or the neck. http://purl.obolibrary.org/obo/UBERON_0011004 pharyngeal arch cartilage http://purl.obolibrary.org/obo/UBERON_0003933 cranial cartilage A cartilage element that is part of a splanchnocranium. http://purl.obolibrary.org/obo/UBERON_0011108 synovial joint of pectoral girdle http://purl.obolibrary.org/obo/UBERON_0008114 joint of girdle A synovial joint that is part of a pectoral girdle region. http://purl.obolibrary.org/obo/UBERON_0011120 laryngeal joint http://purl.obolibrary.org/obo/UBERON_0002217 synovial joint A skeletal joint that connects a laryngeal cartilage. http://purl.obolibrary.org/obo/UBERON_0011134 nonsynovial joint http://purl.obolibrary.org/obo/UBERON_0000982 skeletal joint Joint in which the articulating bones or cartilages are connected by ligaments or fibrocartilage without an intervening synovial cavity. Examples: sagittal suture, inferior tibiofibular syndesmosis, costochondral joint, pubic symphysis. http://purl.obolibrary.org/obo/UBERON_0011137 axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011138 postcranial axial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the postcranial axial skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011156 facial skeleton http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull Subdivision of skull that consists of the facial bones. http://purl.obolibrary.org/obo/UBERON_0011158 primary subdivision of skull http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system The skull can be divided into two: the neurocranium and the facial skeleton. http://purl.obolibrary.org/obo/UBERON_0011164 neurocranium bone http://purl.obolibrary.org/obo/UBERON_0004766 cranial bone A bone that is part of a neurocranium [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0011214 nucleus of midbrain tectum http://purl.obolibrary.org/obo/UBERON_0009661 midbrain nucleus A neural nucleus that is part of a midbrain tectum. http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure A multi cell part structure that is part of a central nervous system. http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A subdivision of an anatomical system. http://purl.obolibrary.org/obo/UBERON_0011233 synovial membrane of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0007616 layer of synovial tissue Synovial sac which surrounds parts of one or more tendons. Examples: synovial tendon sheath of manual digit 2, radial bursa. http://purl.obolibrary.org/obo/UBERON_0011249 appendicular skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system Subdivision of the skeletal system which consists of the appendicular skeleton plus associated joints. http://purl.obolibrary.org/obo/UBERON_0011270 dorsal trunk http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk The part of the trunk that is in the dorsum[cjm]. http://purl.obolibrary.org/obo/UBERON_0011299 white matter of telencephalon http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain A partion of white matter that is part of a telencephalon. This can be further subdivided in some species, for example, into hemisphere white matter and the corpus callosum. http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain A portion of gray matter that is part of a telencephalon. http://purl.obolibrary.org/obo/UBERON_0011357 Reissner's fiber http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure An acellular strand that runs from subcommissural organ caudally through the ventricular system and central canal to the ampulla caudalis. Develops from glycoproteins secreted into CSF. http://purl.obolibrary.org/obo/UBERON_0011362 cranial blood vasculature http://purl.obolibrary.org/obo/UBERON_0004537 blood vasculature A blood vasculature that is part of a head. http://purl.obolibrary.org/obo/UBERON_0011566 lumen of esophagus http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a esophagus. http://purl.obolibrary.org/obo/UBERON_0011582 paired limb/fin skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in an individual limb or fin. http://purl.obolibrary.org/obo/UBERON_0011585 cell condensation http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Anatomical structure that is an aggregation of similar cells from which cartilages and bones form, and from which chondrogenesis and osteogenesis are initiated during repair and/or regeneration. (Hall and Miyake 1995). http://purl.obolibrary.org/obo/UBERON_0011595 jaw region http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A subdivision of the head that corresponds to the jaw skeleton, containing both soft tissue, skeleton and teeth (when present). The jaw region is divided into upper and lower regions. http://purl.obolibrary.org/obo/UBERON_0011642 oral epithelium from ectoderm http://purl.obolibrary.org/obo/UBERON_0010371 ecto-epithelium An epithelium that develops_from a ectoderm and is part of a oral epithelium. http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A major subdivision of an organism that divides an organism along its main body axis (typically anterio-posterior axis). In vertebrates, this is based on the vertebral column. http://purl.obolibrary.org/obo/UBERON_0011695 embryonic cardiovascular system http://purl.obolibrary.org/obo/UBERON_0004535 cardiovascular system A cardiovascular system that is part of a conceptus. http://purl.obolibrary.org/obo/UBERON_0011772 lower jaw opening http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is part of a bone of lower jaw. http://purl.obolibrary.org/obo/UBERON_0011775 vagus nerve nucleus http://purl.obolibrary.org/obo/UBERON_0009662 hindbrain nucleus A cranial nerve nucleus that is associated with a vagus nerve. http://purl.obolibrary.org/obo/UBERON_0011777 nucleus of spinal cord http://purl.obolibrary.org/obo/UBERON_0000125 neural nucleus A neural nucleus that is part of the spinal cord. http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region http://purl.obolibrary.org/obo/UBERON_0001021 nerve A nerve that is part of a head. http://purl.obolibrary.org/obo/UBERON_0011814 non-neurogenic ectodermal placode http://purl.obolibrary.org/obo/UBERON_0005085 ectodermal placode Ectodermal placode that does not develop into a component of the nervous system. http://purl.obolibrary.org/obo/UBERON_0011820 atrioventricular region http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junction that divides and overlaps with and atrium and a ventricle in the heart. http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Connective tissue, which consists of a population of connective tissue cells, the intercellular matrix of which contains an irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, mucoid tissue, connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue Irregular connective tissue is an irregular connective tissue, the intercellular matrix of which contains a dense irregular network of collagen and elastic fiber bundles. Examples: connective tissue of peritoneum, connective tissue of fibrous pericardium. http://purl.obolibrary.org/obo/UBERON_0011823 dense connective tissue http://purl.obolibrary.org/obo/UBERON_0002384 connective tissue Dense connective tissue is mainly composed of collagen type I. Crowded between the collagen fibers are rows of fibroblasts, fiber-forming cells, that manufacture the fibers. Dense connective tissue forms strong, rope-like structures such as tendons and ligaments. Tendons attach skeletal muscles to bones; ligaments connect bones to bones at joints. Ligaments are more stretchy and contain more elastic fibers than tendons. Dense connective tissue also make up the lower layers of the skin (dermis), where it is arranged in sheets. http://purl.obolibrary.org/obo/UBERON_0011825 loose connective tissue http://purl.obolibrary.org/obo/UBERON_0011821 irregular connective tissue Irregular connective tissue, the intercellular matrix of which contains a sparse irregular network of collagen and elastic fiber bundles. Examples: areolar tissue, neuroglial tissue, mucoid tissue. http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland http://purl.obolibrary.org/obo/UBERON_0009842 glandular acinus An acinus that is part of a exocrine gland. http://purl.obolibrary.org/obo/UBERON_0011861 aorta collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of aorta tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011862 pulmonary collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of pulmonary tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011863 bone collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of bone tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011864 tendon collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of tendon tissue that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011865 corneal stroma collagen fibril http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils The connective tissue bundles in the extracellular matrix of corneal stroma that are composed of collagen, and play a role in tissue strength and elasticity. http://purl.obolibrary.org/obo/UBERON_0011892 anterior uvea http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest Front (ventral) portion of the vascular, pigmentary, or middle coat of the eye, including the ciliary body and the iris. http://purl.obolibrary.org/obo/UBERON_0011899 epimysium http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue Epimysium is a layer of connective tissue which ensheaths the entire muscle. It is composed of dense irregular connective tissue. It is continuous with fascia and other connective tissue wrappings of muscle including the endomysium, and perimysium. It is also continuous with tendons where it becomes thicker and collagenous. http://purl.obolibrary.org/obo/UBERON_0011919 yolk sac blood island http://purl.obolibrary.org/obo/UBERON_0003061 blood island Masses of developing blood cells attached to endothelium in the yolk sac. http://purl.obolibrary.org/obo/UBERON_0011925 preganglionic autonomic fiber http://purl.obolibrary.org/obo/UBERON_0003041 trigeminal nerve fibers Nerve fibers which project from the central nervous system to autonomic ganglia. In the sympathetic division most preganglionic fibers originate with neurons in the intermediolateral column of the spinal cord, exit via ventral roots from upper thoracic through lower lumbar segments, and project to the paravertebral ganglia; there they either terminate in synapses or continue through the splanchnic nerves to the prevertebral ganglia. In the parasympathetic division the fibers originate in neurons of the brain stem and sacral spinal cord. In both divisions the principal transmitter is acetylcholine but peptide cotransmitters may also be released. http://purl.obolibrary.org/obo/UBERON_0011927 preganglionic sympathetic fiber http://purl.obolibrary.org/obo/UBERON_0011925 preganglionic autonomic fiber A cholinergic axonal fiber projecting from the CNS to a sympathetic ganglion. http://purl.obolibrary.org/obo/UBERON_0011930 preganglionic parasympathetic fiber http://purl.obolibrary.org/obo/UBERON_0011925 preganglionic autonomic fiber A cholinergic axonal fibers projecting from the CNS to a parasympathetic ganglion. http://purl.obolibrary.org/obo/UBERON_0011997 coelom http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The aggregate of the coelemic cavity lumen plus the membranes that line the lumen. http://purl.obolibrary.org/obo/UBERON_0012054 myocoele http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity The cavity within a myotome. http://purl.obolibrary.org/obo/UBERON_0012075 replacement bone http://purl.obolibrary.org/obo/UBERON_0010522 replacement element Bone that forms as a replacement of another structural tissue. http://purl.obolibrary.org/obo/UBERON_0012082 bronchial lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical cavity that is part of a bronchus. http://purl.obolibrary.org/obo/UBERON_0012180 head or neck skin http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is part of a craniocervical region. http://purl.obolibrary.org/obo/UBERON_0012193 phrenic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein The veins that run parallel to the phrenic arteries which include the two superior and two inferior phrenic veins. http://purl.obolibrary.org/obo/UBERON_0012254 abdominal aorta artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery An artery that originates from the abdominal aorta. http://purl.obolibrary.org/obo/UBERON_0012274 columnar epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An epithelium that consists of columnar epithelial cells. Columnar epithelia are epithelial cells whose heights are at least four times their width. Columnar epithelia are divided into simple (or unilayered), and the rarer stratified (or multi-layered).[WP, modified]. http://purl.obolibrary.org/obo/UBERON_0012275 meso-epithelium http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure Epithelium that derives from the mesoderm. [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0012314 embryonic facial prominence http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure One of five swellings formed during the development of the face. http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery http://purl.obolibrary.org/obo/UBERON_0003502 neck blood vessel An artery of the neck. http://purl.obolibrary.org/obo/UBERON_0012321 deep cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery The deep cervical artery (Profunda cervicalis) is an artery of the neck. http://purl.obolibrary.org/obo/UBERON_0012324 transverse cervical artery http://purl.obolibrary.org/obo/UBERON_0012320 cervical artery The transverse cervical artery (transverse artery of neck, transversa colli artery) is a branch of the thyrocervical trunk, running at a higher level than the suprascapular artery. http://purl.obolibrary.org/obo/UBERON_0012360 bone of jaw http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A bone element that is part of a jaw region. http://purl.obolibrary.org/obo/UBERON_0012375 subserosa http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer A layer of tissue between the muscularis and serosa. http://purl.obolibrary.org/obo/UBERON_0012418 respiratory system venous smooth muscle http://purl.obolibrary.org/obo/UBERON_0004696 venous system smooth muscle A smooth muscle tissue that is part of a respiratory system venous blood vessel. http://purl.obolibrary.org/obo/UBERON_0012429 hematopoietic tissue http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue Blood-forming tissue, consisting of reticular fibers and cells. http://purl.obolibrary.org/obo/UBERON_0012430 tunica fibrosa of eyeball http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest The sclera and cornea form the fibrous tunic of the bulb of the eye; the sclera is opaque, and constitutes the posterior five-sixths of the tunic; the cornea is transparent, and forms the anterior sixth. http://purl.obolibrary.org/obo/UBERON_0012467 enclosed anatomical space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space with no opening to another space or to the exterior. http://purl.obolibrary.org/obo/UBERON_0012475 skeleton of pectoral complex http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton The collection of all skeletal elements in a pectoral complex - i.e. the combination of free limb or fin plus pectoral girdle. http://purl.obolibrary.org/obo/UBERON_0012504 adventitia of esophagus http://purl.obolibrary.org/obo/UBERON_0005742 adventitia An adventitia that is part of a esophagus. http://purl.obolibrary.org/obo/UBERON_0013126 vein of abdomen http://purl.obolibrary.org/obo/UBERON_0003497 abdomen blood vessel A vein that is part of a abdomen. http://purl.obolibrary.org/obo/UBERON_0013127 pulmonary venous system http://purl.obolibrary.org/obo/UBERON_0002049 vasculature The part of the venous system that drains the lungs[Kardong]. http://purl.obolibrary.org/obo/UBERON_0013136 vein of lip http://purl.obolibrary.org/obo/UBERON_0001638 vein A vein that drains a lip. http://purl.obolibrary.org/obo/UBERON_0013140 systemic vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Any vein within the general circulation that transports blood back to the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0013151 choroidal artery http://purl.obolibrary.org/obo/UBERON_0001637 artery One of two arteries (anterior and posterior choroidal artery) that supply blood to the choroid plexus, optic tract, hippocampus, globus pallidus, and other various brain regions. http://purl.obolibrary.org/obo/UBERON_0013161 left lateral ventricle http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A telencephalic ventricle that is in_the_left_side_of a telencephalon. http://purl.obolibrary.org/obo/UBERON_0013162 right lateral ventricle http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure A telencephalic ventricle that is in_the_right_side_of a telencephalon. http://purl.obolibrary.org/obo/UBERON_0013232 serous acinus http://purl.obolibrary.org/obo/UBERON_0011858 acinus of exocrine gland The secretory unit of a serous gland. The acinar portion is composed of serous secreting cells. http://purl.obolibrary.org/obo/UBERON_0013411 cranial cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity Anatomical cavity that is the lumen of the skull and contains the brain. http://purl.obolibrary.org/obo/UBERON_0013479 lung endothelium http://purl.obolibrary.org/obo/UBERON_0004702 respiratory system blood vessel endothelium A blood vessel endothelium that is part of a lung [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0013514 space surrounding organism http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space The space that surrounds an organism. http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull http://purl.obolibrary.org/obo/UBERON_0005744 bone foramen Anatomical space that is an opening in a bone of the skull. http://purl.obolibrary.org/obo/UBERON_0013686 anatomical conduit space http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space which is the lumen of some anatomical conduit and connects two or more spaces together[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0013694 brain endothelium http://purl.obolibrary.org/obo/UBERON_0001986 endothelium Vascular endothelium found in blood vessels of the blood-brain-barrier. http://purl.obolibrary.org/obo/UBERON_0013700 axial musculature http://purl.obolibrary.org/obo/UBERON_0001015 musculature Musculature of the head and neck, spine, and ribs. http://purl.obolibrary.org/obo/UBERON_0013701 main body axis http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision A principle subdivision of an organism that includes all structures along the primary axis, typically the anterior-posterior axis, from head to tail, including structures of the body proper where present (for example, ribs), but excluding appendages. http://purl.obolibrary.org/obo/UBERON_0013702 body proper http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision The region of the organism associated with the visceral organs. http://purl.obolibrary.org/obo/UBERON_0013704 notochordal canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A tubular passage that extends from the primitive pit into the head process during the early stages of embryonic development in mammals. It perforates the splanchnopleure layer so that the yolk sac and the amnion are connected temporarily. http://purl.obolibrary.org/obo/UBERON_0013727 notochordal fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid Fluid contained within the notochordal canal. http://purl.obolibrary.org/obo/UBERON_0013754 integumentary system layer http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer An organ component layer that is part of a integumental system. http://purl.obolibrary.org/obo/UBERON_0013755 arterial blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a artery. http://purl.obolibrary.org/obo/UBERON_0013756 venous blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a vein. http://purl.obolibrary.org/obo/UBERON_0013757 capillary blood http://purl.obolibrary.org/obo/UBERON_0000178 blood A blood that is part of a capillary. http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element http://purl.obolibrary.org/obo/UBERON_0000062 organ Any of the organs or elements that are part of the digestive system. Examples: tongue, esophagus, spleen, crop, lunge feeding organ, tooth elements. http://purl.obolibrary.org/obo/UBERON_0013768 great vessel of heart http://purl.obolibrary.org/obo/UBERON_0001981 blood vessel Great vessels is a term used to refer collectively to the large vessels that bring blood to and from the heart. http://purl.obolibrary.org/obo/UBERON_0014283 piriform cortex layer 3 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Deepest of 3 cytoarchitecturally defined layers of the piriform cortex characterized by a moderately high density of pyramidal cells and large numbers of basal dendrites descending from pyramidal cells in layer 2. http://purl.obolibrary.org/obo/UBERON_0014371 future telencephalon http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Embryonic structure that gives rise to the telencephalon. http://purl.obolibrary.org/obo/UBERON_0014387 mesenchyme derived from neural crest http://purl.obolibrary.org/obo/UBERON_0010313 neural crest-derived structure Mesenchyme that develops_from the neural crest[Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0014389 gustatory papilla of tongue http://purl.obolibrary.org/obo/UBERON_0001726 papilla of tongue A papilla that contain taste buds, including the fungiform, foliate, and circumvallate papillae. http://purl.obolibrary.org/obo/UBERON_0014398 respiratory muscle http://purl.obolibrary.org/obo/UBERON_0003831 respiratory system muscle Muscle that is part of the respiratory system. http://purl.obolibrary.org/obo/UBERON_0014399 sinusoidal space http://purl.obolibrary.org/obo/UBERON_0010161 lumen of blood vessel An anatomical space that is enclosed by a sinusoid. http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure A part of the body present only in a specific gender. http://purl.obolibrary.org/obo/UBERON_0014404 female anatomical structure http://purl.obolibrary.org/obo/UBERON_0014402 sex-specific anatomical structure A part of the body present only in females. http://purl.obolibrary.org/obo/UBERON_0014451 tongue taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located on the tongue, situated on a gustatory papilla. http://purl.obolibrary.org/obo/UBERON_0014452 gustatory epithelium of tongue http://purl.obolibrary.org/obo/UBERON_0003357 epithelium of tongue A gustatory epithelium that is part of a tongue. http://purl.obolibrary.org/obo/UBERON_0014454 visceral abdominal adipose tissue http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region Subcutaneous adipose tissue that is located in the peritoneal cavity. http://purl.obolibrary.org/obo/UBERON_0014455 subcutaneous abdominal adipose tissue http://purl.obolibrary.org/obo/UBERON_0007808 adipose tissue of abdominal region Subcutaneous adipose tissue that is located in the abdominal region. http://purl.obolibrary.org/obo/UBERON_0014477 thoracic skeleton http://purl.obolibrary.org/obo/UBERON_0010912 subdivision of skeleton Subdivision of skeletal system that consists of all skeletal elements in the thoracic region of the trunk. In most vertebrates this is the rib cage and sternum. http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0004111 anatomical conduit A subdivision of the central canal of the spinal cord along its anterior-posterior axis. This is typically subdivided into cervical, thoracic, lumbar and sacral segments. http://purl.obolibrary.org/obo/UBERON_0014540 white matter lamina of cerebellum http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis The white laminae of cerebellum is subdivision of the cerebellar cortex comprised of myelinated axons lying deep to the granule cell layer of the cerebellar cortex. http://purl.obolibrary.org/obo/UBERON_0014541 thoracic division of spinal cord central canal http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal Part of spinal cord central canal contained in the thoracic spinal cord. It is continuous rostrally with the cervical spinal cord central canal and caudally with the lumbar spinal cord central canal. http://purl.obolibrary.org/obo/UBERON_0014542 cervical division of cord spinal central canal http://purl.obolibrary.org/obo/UBERON_0014538 subdivision of spinal cord central canal Part of central canal contained within the cervical spinal cord. It is continuous caudally with the thoracic spinal cord central canal and rostrally with the fourth ventricle of the brain via the obex. http://purl.obolibrary.org/obo/UBERON_0014610 thoracic spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord A ventral horn of spinal cord that is part of a thoracic spinal cord. http://purl.obolibrary.org/obo/UBERON_0014613 cervical spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord A gray matter of spinal cord that is part of a cervical spinal cord. http://purl.obolibrary.org/obo/UBERON_0014614 cervical spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord A white matter of spinal cord that is part of a cervical spinal cord. http://purl.obolibrary.org/obo/UBERON_0014621 cervical spinal cord ventral horn http://purl.obolibrary.org/obo/UBERON_0002257 ventral horn of spinal cord A ventral horn of spinal cord that is part of a cervical spinal cord. http://purl.obolibrary.org/obo/UBERON_0014636 thoracic spinal cord gray matter http://purl.obolibrary.org/obo/UBERON_0002315 gray matter of spinal cord A gray matter of spinal cord that is part of a thoracic spinal cord. http://purl.obolibrary.org/obo/UBERON_0014637 thoracic spinal cord white matter http://purl.obolibrary.org/obo/UBERON_0002318 white matter of spinal cord A white matter of spinal cord that is part of a thoracic spinal cord. http://purl.obolibrary.org/obo/UBERON_0014649 white matter of medulla oblongata http://purl.obolibrary.org/obo/UBERON_0019262 white matter of myelencephalon A white matter that is part of a medulla oblongata. http://purl.obolibrary.org/obo/UBERON_0014704 pleuroperitoneal canal lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space An anatomical space that is enclosed by a pleuroperitoneal canal. http://purl.obolibrary.org/obo/UBERON_0014705 median lingual swelling epithelium http://purl.obolibrary.org/obo/UBERON_0005911 endo-epithelium An epithelium that is part of a median lingual swelling. http://purl.obolibrary.org/obo/UBERON_0014775 prosomere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive forebrain. http://purl.obolibrary.org/obo/UBERON_0014776 midbrain neuromere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive midbrain. http://purl.obolibrary.org/obo/UBERON_0014777 spinal neuromere http://purl.obolibrary.org/obo/UBERON_0004731 neuromere A neuromere that is part of the presumptive spinal cord. http://purl.obolibrary.org/obo/UBERON_0014790 lingual septum http://purl.obolibrary.org/obo/UBERON_0003037 septum The lingual septum consists of a vertical layer of fibrous tissue, extending throughout the entire length of the median plane of the tongue, though not quite reaching the dorsum. It is thicker behind than in front, and occasionally contains a small fibrocartilage, about 6 mm. in length. It is well displayed by making a vertical section across the organ. http://purl.obolibrary.org/obo/UBERON_0014793 musculature of pectoral complex http://purl.obolibrary.org/obo/UBERON_0001015 musculature Any collection of muscles that is part of a pectoral complex. The pectoral complex comprises the pectoral girdle and the associated limb or fin. http://purl.obolibrary.org/obo/UBERON_0014794 pectoral appendage muscle http://purl.obolibrary.org/obo/UBERON_0010891 pectoral complex muscle Any muscle organ that is part of a pectoral appendage (forelimb or pectoral fin). http://purl.obolibrary.org/obo/UBERON_0014891 brainstem white matter http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter White matter that is part of a brainstem [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0014892 skeletal muscle organ, vertebrate http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ A muscle organ that consists of skeletal muscle tissue ensheathed in epimysium, that develops from myotome and that is innervated by some somatic motor neuron. Skeletal muscles are typically attached (via a tendon) to a bone but there are exceptions (e.g. intrinsic tongue muscles). http://purl.obolibrary.org/obo/UBERON_0014903 primordial vasculature http://purl.obolibrary.org/obo/UBERON_0001048 primordium A portion of tissue that will develop into vasculature. http://purl.obolibrary.org/obo/UBERON_0014907 intersomitic vessel http://purl.obolibrary.org/obo/UBERON_0004120 mesoderm-derived structure One of the primary blood vessel sprouts that originate from the dorsal aorta and posterior cardinal vein and align dorsoventrally at the myotomal boundaries between somites. http://purl.obolibrary.org/obo/UBERON_0015129 epicardial fat http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat Visceral intrapericardial fat contiguous with the myocardial surface. http://purl.obolibrary.org/obo/UBERON_0015152 gland of ocular region http://purl.obolibrary.org/obo/UBERON_0002530 gland A gland that is typically found in or near the orbital region, in or around either the medial or lateral canthi, and is typically associated with secretions onto the eyeball or associated ducts. Includes the Harderian, nictitans and lacrimal glands. http://purl.obolibrary.org/obo/UBERON_0015165 multi-unit eye http://purl.obolibrary.org/obo/UBERON_0000970 eye An eye consisting of multiple light-sensing organs. http://purl.obolibrary.org/obo/UBERON_0015178 somite border http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A region of somite adjacent to presomitic mesoderm. http://purl.obolibrary.org/obo/UBERON_0015179 somite boundary epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Epithelium located in the intersomitic region. http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group An anatomical group whose component structures share a common function. http://purl.obolibrary.org/obo/UBERON_0015204 glandular system http://purl.obolibrary.org/obo/UBERON_0015203 non-connected functional system A non-connected functional system that is composed primarily of a gland. http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any structure that is placed on one side of the left-right axis of a bilaterian. http://purl.obolibrary.org/obo/UBERON_0015228 circulatory organ http://purl.obolibrary.org/obo/UBERON_0003103 compound organ A hollow, muscular organ, which, by contracting rhythmically, contributes to the circulation of lymph, blood or analogs. Examples: a chambered vertebrate heart; the tubular peristaltic heart of ascidians; the dorsal vessel of an insect; the lymoh heart of a reptile. http://purl.obolibrary.org/obo/UBERON_0015238 pineal complex http://purl.obolibrary.org/obo/UBERON_0000477 anatomical cluster A cluster in the epithalamus that consists of the pineal body and any associated structures, such as the parapineal gland or the parietal organ. The complex is poorly developed in mammals. http://purl.obolibrary.org/obo/UBERON_0015329 respiratory system basement membrane http://purl.obolibrary.org/obo/UBERON_0005769 basement membrane of epithelium A basement membrane of epithelium that is part of a respiratory system. http://purl.obolibrary.org/obo/UBERON_0015783 smooth muscle layer in fatty layer of subcutaneous tissue http://purl.obolibrary.org/obo/UBERON_0001135 smooth muscle tissue A smooth muscle tissue that is part of a hypodermis. http://purl.obolibrary.org/obo/UBERON_0015808 eye epithelium http://purl.obolibrary.org/obo/UBERON_0007625 pigment epithelium of eye An epithelium that is part of a camera-type eye. http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium An epithelium that is part of a foregut. http://purl.obolibrary.org/obo/UBERON_0016405 pulmonary capillary http://purl.obolibrary.org/obo/UBERON_0003526 respiratory system capillary A capillary that is part of a lung. http://purl.obolibrary.org/obo/UBERON_0016458 esophageal hiatus http://purl.obolibrary.org/obo/UBERON_0000161 orifice A hole in the diaphragm through which the esophagus passes. http://purl.obolibrary.org/obo/UBERON_0016509 cavity of right ventricle http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the right ventricle of the heart. http://purl.obolibrary.org/obo/UBERON_0016513 cavity of left atrium http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the left atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0016522 cavity of right atrium http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the right atrium of the heart. http://purl.obolibrary.org/obo/UBERON_0016526 lobe of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0000064 organ part Subdivision of telencephalon which is one of a number of subdivisions of each hemisphere separated by both real landmarks (sulci and fissures) and arbitrary boundaries[FMA,modified]. http://purl.obolibrary.org/obo/UBERON_0016529 cortex of cerebral lobe http://purl.obolibrary.org/obo/UBERON_0005401 cerebral hemisphere gray matter Grey matter neocortex region of a lobe of the cerebral hemisphere. http://purl.obolibrary.org/obo/UBERON_0016545 pharyngeal ectoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue The external part of the developing pharynx that is made of ectoderm. During vertebrate development, pockets form in pharyngeal ectoderm between the pharyngeal arches. http://purl.obolibrary.org/obo/UBERON_0016548 central nervous system gray matter layer http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer A layer of of the central nervous system that is part of gray matter. http://purl.obolibrary.org/obo/UBERON_0016549 central nervous system white matter layer http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer A layer of of the central nervous system that is composed of white matter. http://purl.obolibrary.org/obo/UBERON_0016554 white matter of midbrain http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter A white matter that is part of the midbrain. http://purl.obolibrary.org/obo/UBERON_0016565 cerebral blood vessel http://purl.obolibrary.org/obo/UBERON_0003499 brain blood vessel A blood vessel that is part of a cerebellum. http://purl.obolibrary.org/obo/UBERON_0016855 ventral part of optic cup http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The ventral region of the optic cup that gives rise to the ventral part of the retina. http://purl.obolibrary.org/obo/UBERON_0016879 future central nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the central nervous system. http://purl.obolibrary.org/obo/UBERON_0016880 future nervous system http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Primordium that develops into the nervous system. http://purl.obolibrary.org/obo/UBERON_0016887 entire extraembryonic component http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the conceptus that may be lost before birth or will be discarded at birth, or when the embryo becomes an independent organism. http://purl.obolibrary.org/obo/UBERON_0016888 transitional anatomical structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure An embryonic anatomical entity that will turn into one or more other anatomical entities, perhaps with other anatomical entities, later in development. http://purl.obolibrary.org/obo/UBERON_0017650 developing mesenchymal structure http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure A mesenchyme-derived anatomical entity undergoing a transtion to become another structure. http://purl.obolibrary.org/obo/UBERON_0017672 abdominal viscera http://purl.obolibrary.org/obo/UBERON_0005172 abdomen element A viscus that is part of a abdomen. http://purl.obolibrary.org/obo/UBERON_0018150 skin of lower lip http://purl.obolibrary.org/obo/UBERON_0001458 skin of lip A zone of skin that is part of a lower lip. http://purl.obolibrary.org/obo/UBERON_0018239 rhombomere boundary http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction A boundary delimiting a rhombomere. http://purl.obolibrary.org/obo/UBERON_0018251 meningeal vein http://purl.obolibrary.org/obo/UBERON_0001638 vein One of the veins draining a meninix. http://purl.obolibrary.org/obo/UBERON_0018257 submucosa of digestive tract http://purl.obolibrary.org/obo/UBERON_0000009 submucosa Any portion of submucosa that lines the digestive tract. http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Any organ component layer that consists of muscle tissue. http://purl.obolibrary.org/obo/UBERON_0018321 foramen for glossopharyngeal nerve http://purl.obolibrary.org/obo/UBERON_0013685 foramen of skull Foramen that allows the passge of the glossopharyngeal nerve (cranial nerve IX). http://purl.obolibrary.org/obo/UBERON_0018544 trigeminal nerve muscle http://purl.obolibrary.org/obo/UBERON_0001630 muscle organ Muscle innervated by the trigeminal nerve (Cranial Nerve V). http://purl.obolibrary.org/obo/UBERON_0018674 heart vasculature http://purl.obolibrary.org/obo/UBERON_0006876 vasculature of organ An interconnected tubular multi-tissue structure that contains fluid that is actively transported around the heart. http://purl.obolibrary.org/obo/UBERON_0019143 intramuscular adipose tissue http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Adipose tissue which is located throughout skeletal muscle and is responsible for the marbling seen in certain cuts of beef. In humans, excess accumulation of intramuscular fat is associated with insulin resistance and type 2 diabetes. http://purl.obolibrary.org/obo/UBERON_0019204 skin epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium Any region of epithelium that is part of a skin region. http://purl.obolibrary.org/obo/UBERON_0019207 chorioretinal region http://purl.obolibrary.org/obo/UBERON_0000481 multi-tissue structure The part of the eye that consists of both the retina and the optic choroid. http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter A white matter that is part of the hindbrain. http://purl.obolibrary.org/obo/UBERON_0019261 white matter of forebrain http://purl.obolibrary.org/obo/UBERON_0003544 brain white matter A white matter that is part of the forebrain. http://purl.obolibrary.org/obo/UBERON_0019262 white matter of myelencephalon http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain A white matter that is part of the myelencephalon. http://purl.obolibrary.org/obo/UBERON_0019319 exocrine gland of integumental system http://purl.obolibrary.org/obo/UBERON_0003297 gland of integumental system An exocrine gland that is part of a integumental system. http://purl.obolibrary.org/obo/UBERON_0020358 accessory XI nerve nucleus http://purl.obolibrary.org/obo/UBERON_0007635 nucleus of medulla oblongata The spinal accessory nucleus lies within the cervical spinal cord (C1-C5) in the ventral horn. The nucleus ambiguus is classically said to provide the 'cranial component' of the accessory nerve. However, the very existence of this cranial component has been recently questioned and seen as contributing exclusively to the vagus nerve. The terminology continues to be used in describing both human anatomy, and that of other animals. http://purl.obolibrary.org/obo/UBERON_0022293 reproductive gland secretion http://purl.obolibrary.org/obo/UBERON_0000463 organism substance A portion of organism substance that is secreted by a reproductive gland. http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0005162 multi cell part structure Single layer of a laminar structure, identified by different density, arrangement or size of cells and processes arranged in flattened layers or lamina[CUMBO]. http://purl.obolibrary.org/obo/UBERON_0022317 olfactory cortex layer 1 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Surface layer of the olfactory cortex that contains dendrites, fiber systems and a small number of neurons. It has been divided into a superficial part and a deep part. http://purl.obolibrary.org/obo/UBERON_0022318 olfactory cortex layer 2 http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer Middle layer of olfactory cortex lying deep to layer 1 and superficial to layer 3, characterized by a compact layer of cell bodies. It can be divided into a superficial part and a deep part. http://purl.obolibrary.org/obo/UBERON_0022350 visceral serous membrane http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Serous membrane layer that is adjacent to and lines an organ. http://purl.obolibrary.org/obo/UBERON_0022351 parietal serous membrane http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer Serous membrane layer that lines to a body cavity. http://purl.obolibrary.org/obo/UBERON_0022361 lung field http://purl.obolibrary.org/obo/UBERON_0007688 anlage A specific region of the foregut into the area in which the lung will develop. http://purl.obolibrary.org/obo/UBERON_0024045 white matter of the cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0019291 white matter of metencephalon White matter that lies deep to the granular cell layer of the cerebellar cortex. It contains afferents to the cerebellar cortex and axons that run between the cerebellar cortex and the deep cerebellar nuclei. http://purl.obolibrary.org/obo/UBERON_0024090 chemoarchitectural part of brain http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain Regional part of an anatomical region that is revealed by the use of a stain that reveals chemoarchitecture. http://purl.obolibrary.org/obo/UBERON_0027368 matrix compartment http://purl.obolibrary.org/obo/UBERON_0025736 chemoarchitectural part of striatum The larger of two chemoarchitectural compartments identified in the neostriatum through differential staining for various biochemical markers. It usually is identified through differentially high staining for acetylcholinesterase and calbinin D28K. http://purl.obolibrary.org/obo/UBERON_0027371 striosome http://purl.obolibrary.org/obo/UBERON_0025736 chemoarchitectural part of striatum One of two compartments identified in the neostriatum, particularly the caudate nucleus, on the basis of differential staining for several biochemical markers such as acetylcholinesterase and calbindin. In individual sections, the striosomes appear as small patches of differentially high or low staining activity. In three dimensions, they form a 3D labyrinth extending throughout the caudate nucleus and in the putamen. http://purl.obolibrary.org/obo/UBERON_0029001 matrix compartment of caudate nucleus http://purl.obolibrary.org/obo/UBERON_0027368 matrix compartment Matrix compartment located in the caudate nucleus. http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium An embryonic or larval epithelium that is committed to form part of the nervous system. http://purl.obolibrary.org/obo/UBERON_0034706 proliferating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium An epithelium that is undergoing proliferation to provide large numbers of neuronal cells. http://purl.obolibrary.org/obo/UBERON_0034707 differentiating neuroepithelium http://purl.obolibrary.org/obo/UBERON_0034705 developing neuroepithelium A neuroepithelium some of whose cells are undergoing terminal differentiation to become neuronal cells. http://purl.obolibrary.org/obo/UBERON_0034711 cortical preplate http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex The layer of the developing cerebral cortex that is formed from the first cohort of neurons to migrate out of the cortical ventricular zone; split by the second wave into marginal zone and subplate. http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any of the cranial nerves, or their central nervous system analogs (the optic tract, the epiphyseal tract). These analogs are not true nerves, and are instead evaginated sensory afferents emanating from the brain. http://purl.obolibrary.org/obo/UBERON_0034714 epiphyseal tract http://purl.obolibrary.org/obo/UBERON_0034713 cranial neuron projection bundle A cranial nerve fiber tract that innervates the parietal eye. http://purl.obolibrary.org/obo/UBERON_0034715 pineal tract http://purl.obolibrary.org/obo/UBERON_0034714 epiphyseal tract A cranial nerve fiber tract that innervates the pineal body. http://purl.obolibrary.org/obo/UBERON_0034717 integumental taste bud http://purl.obolibrary.org/obo/UBERON_0001727 taste bud A taste bud that is located external to the digestive tube, on the head or body, as found in species such as goldfish. http://purl.obolibrary.org/obo/UBERON_0034719 lip taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located on a lip. http://purl.obolibrary.org/obo/UBERON_0034720 head taste bud http://purl.obolibrary.org/obo/UBERON_0034717 integumental taste bud A taste bud that is located on the skin of the head. http://purl.obolibrary.org/obo/UBERON_0034721 pharyngeal taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located in the pharynx. http://purl.obolibrary.org/obo/UBERON_0034724 esophageal taste bud http://purl.obolibrary.org/obo/UBERON_0013765 digestive system element A taste bud that is located in the esophagus. http://purl.obolibrary.org/obo/UBERON_0034726 trunk taste bud http://purl.obolibrary.org/obo/UBERON_0034717 integumental taste bud A taste bud that is located on the skin of the trunk. http://purl.obolibrary.org/obo/UBERON_0034728 autonomic nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The autonomic nerve is a small nerve which carries postganglionic sympathetic and parasympathetic neurons from the zygomaticotemporal nerve; a branch of the maxillary nerve, to the lacrimal nerve; a branch of the ophthalmic nerve. These neurons derive from the superior cervical ganglion and the pterygopalatine ganglion respectively. They will travel to the lacrimal gland via the lacrimal nerve. Parasympathetic will induce lacrimation and vice versa. http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas http://purl.obolibrary.org/obo/UBERON_0000463 organism substance Any substance in the body or expelled from the body that is in a gaseous state. http://purl.obolibrary.org/obo/UBERON_0034874 air in respiratory system http://purl.obolibrary.org/obo/UBERON_0034947 gas in respiratory system Any portion of gas located in a part of the respiratory system that is composed primarily of air. http://purl.obolibrary.org/obo/UBERON_0034876 future neurohypophysis http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure The outgrowth of neuroectoderm located on the floor of the embryonic hypothalamus that gives rise to the neurohypophysis (posterior lobe) of the pituitary gland. http://purl.obolibrary.org/obo/UBERON_0034878 prechordal mesoderm http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure The area of axial mesoderm that develops into the prechordal plate. http://purl.obolibrary.org/obo/UBERON_0034903 left atrium endocardium http://purl.obolibrary.org/obo/UBERON_0002166 endocardium of atrium Endocardium that is part of the left atrium. http://purl.obolibrary.org/obo/UBERON_0034907 pineal parenchyma http://purl.obolibrary.org/obo/UBERON_0005158 parenchyma of central nervous system Parenchymal tissue that forms the pineal gland. http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure An multicellular anatomical structure that has subparts of multiple organs as a part. http://purl.obolibrary.org/obo/UBERON_0034922 cell cluster http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure A cluster of cells, largely surrounded by a morphological boundary. http://purl.obolibrary.org/obo/UBERON_0034923 disconnected anatomical group http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity consisting of multiple anatomical structures that are not connected to each other. http://purl.obolibrary.org/obo/UBERON_0034925 anatomical collection http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity A collection of anatomical structures that are alike in terms of their morphology or developmental origin. http://purl.obolibrary.org/obo/UBERON_0034929 external soft tissue zone http://purl.obolibrary.org/obo/UBERON_0010314 structure with developmental contribution from neural crest A region or zone on the surface of an organism that encompasses skin and any adnexa, down through muscles and bounded by underlying skeletal support structures. http://purl.obolibrary.org/obo/UBERON_0034933 layer of smooth muscle tissue http://purl.obolibrary.org/obo/UBERON_0018260 layer of muscle tissue Any organ component layer that consists of smooth muscle tissue. http://purl.obolibrary.org/obo/UBERON_1000021 skin of face http://purl.obolibrary.org/obo/UBERON_0001084 skin of head A zone of skin that is part of the face. http://purl.obolibrary.org/obo/UBERON_2001457 postcranial axial cartilage http://purl.obolibrary.org/obo/UBERON_0007844 cartilage element Cartilage which is part of the axial skeleton. http://purl.obolibrary.org/obo/UBERON_2005260 fenestrated capillary http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium Capillary that has pores in the endothelial cells (60-80 nm in diameter) that are spanned by a diaphragm of radially oriented fibrils and allow small molecules and limited amounts of protein to diffuse. http://purl.obolibrary.org/obo/UBERON_2007013 preplacodal ectoderm http://purl.obolibrary.org/obo/UBERON_0005497 non-neural ectoderm Non neural ectoderm that surrounds the presumptive neural plate and gives rise to neurogenic placodes. http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure http://purl.obolibrary.org/obo/UBERON_0003102 surface structure Structures of the dermis, epidermis, glands and pigment cells recognizable on the external surfaces of the integument. http://purl.obolibrary.org/obo/UBERON_3000972 head external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the external head integument. http://purl.obolibrary.org/obo/UBERON_3000977 body external integument structure http://purl.obolibrary.org/obo/UBERON_3000961 external integument structure Dermal, epidermal, glandular and pigment structures of the body integument. http://purl.obolibrary.org/obo/UBERON_3010200 vasculature of respiratory integument http://purl.obolibrary.org/obo/UBERON_0003504 respiratory system blood vessel Blood vessels in respiratory skin. http://purl.obolibrary.org/obo/UBERON_4200230 surface of bone http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface An anatomical surface that is part of a bone. http://purl.obolibrary.org/obo/PR_000005307 CCAAT/enhancer-binding protein alpha http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CEBPA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000005444 chondrolectin http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CHODL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007479 fibroblast growth factor 1 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human FGF1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007489 fibroblast growth factor 2 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human FGF2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007499 fibroblast growth factor 8 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human FGF8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007597 protein c-Fos http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human FOS gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007857 erythroid transcription factor http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human GATA1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000007858 endothelial transcription factor GATA-2 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human GATA2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000029968 somatotropin hormone family member http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a standalone version of the Hormone_1 domain (Pfam:PF00103). In the immature form, the domain is preceded by a signal peptide. http://purl.obolibrary.org/obo/PR_000032148 lysosome-associated membrane glycoprotein 5 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human LAMP5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000032533 LIM/homeobox protein Lhx6 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human LHX6 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_P01101 protein c-Fos (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A protein c-Fos that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P01731 T-cell surface glycoprotein CD8 alpha chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD8 alpha chain that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P01831 Thy-1 membrane glycoprotein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A Thy-1 membrane glycoprotein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P05532 mast/stem cell growth factor receptor Kit (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A mast/stem cell growth factor receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P05555 integrin alpha-M (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An integrin alpha-M that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P06332 T-cell surface glycoprotein CD4 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD4 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P06800 receptor-type tyrosine-protein phosphatase C (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A receptor-type tyrosine-protein phosphatase C that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P06879 prolactin (mouse) http://purl.obolibrary.org/obo/PR_000013246 prolactin A prolactin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P08508 low affinity immunoglobulin gamma Fc region receptor III (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A low affinity immunoglobulin gamma Fc region receptor III that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P08920 T-cell surface antigen CD2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD2 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35456 urokinase plasminogen activator surface receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A urokinase plasminogen activator surface receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35461 lymphocyte antigen 6G (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A lymphocyte antigen 6G that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P35918 vascular endothelial growth factor receptor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A vascular endothelial growth factor receptor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P37237 fibroblast growth factor 8 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 8 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P97797 tyrosine-protein phosphatase non-receptor type substrate 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tyrosine-protein phosphatase non-receptor type substrate 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q00342 receptor-type tyrosine-protein kinase FLT3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A receptor-type tyrosine-protein kinase FLT3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q05117 tartrate-resistant acid phosphatase type 5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tartrate-resistant acid phosphatase type 5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8VCC9 spondin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A spondin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q9WTK5 nuclear factor NF-kappa-B p100 subunit (mouse) http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit A nuclear factor NF-kappa-B p100 subunit that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/UBERON_0035550 superficial vein http://purl.obolibrary.org/obo/UBERON_0001638 vein Any of the veins carrying deoxygenated blood from the subcutaneous tissue layers. http://purl.obolibrary.org/obo/GO_0061853 regulation of neuroblast migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of neuroblast migration. http://purl.obolibrary.org/obo/GO_0061854 positive regulation of neuroblast migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate or extent of neuroblast migration. http://purl.obolibrary.org/obo/GO_0061855 negative regulation of neuroblast migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration. http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity Material anatomical entity that forms the outermost boundary of an anatomical structure. http://purl.obolibrary.org/obo/GO_0110020 regulation of actomyosin structure organization http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. http://purl.obolibrary.org/obo/PATO_0045001 normal object quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of an object that has a value that is normal or average. http://purl.obolibrary.org/obo/PATO_0045073 normal process quality http://purl.obolibrary.org/obo/PATO_0001236 process quality A quality of a process that has a value that is normal or average. http://purl.obolibrary.org/obo/PATO_0045080 normal virulence http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A virulence which is relatively normal or average http://purl.obolibrary.org/obo/CHEBI_142513 oxime anion http://purl.obolibrary.org/obo/CHEBI_25696 organic anion A organic ion resulting from the deprotonation of the hydroxy group of any oxime. http://purl.obolibrary.org/obo/PHIPO_0000038 mutualism phenotype http://purl.obolibrary.org/obo/PHIPO_0001179 infective ability phenotype A phenotype which affects the balance of symbiotic mutualism, mutualism describes an interaction between two symbionts (where the larger is usually the host), results in positive (beneficial) effects on reproduction and/or survival of both species. http://purl.obolibrary.org/obo/PHIPO_0000039 normal mutualism http://purl.obolibrary.org/obo/PHIPO_0000038 mutualism phenotype A phenotype in which the interaction is the same as the wild-type, no asymptomatic colonisation or disease formation symptoms are visible. http://purl.obolibrary.org/obo/PHIPO_0000040 abnormal mutualism http://purl.obolibrary.org/obo/PHIPO_0000038 mutualism phenotype A phenotype in which the balance of symbiotic mutualism has been disrupted compared to the normal interaction. http://purl.obolibrary.org/obo/PHIPO_0000043 abnormal reproduction phenotype http://purl.obolibrary.org/obo/PHIPO_0000161 reproductive phenotype A single species phenotype where reproduction is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000044 normal reproduction phenotype http://purl.obolibrary.org/obo/PHIPO_0000161 reproductive phenotype A single species phenotype where reproduction is normal (indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000045 normal asexual reproduction http://purl.obolibrary.org/obo/PHIPO_0000044 normal reproduction phenotype A single species phenotype where the asexual reproduction process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is normal (indistinguishable from wild type)(GO:0019954). http://purl.obolibrary.org/obo/PHIPO_0000046 normal sexual reproduction http://purl.obolibrary.org/obo/PHIPO_0000044 normal reproduction phenotype A single species phenotype where the sexual reproduction process in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is normal (indistinguishable from wild type) (GO:0019953). http://purl.obolibrary.org/obo/PHIPO_0000047 abnormal asexual reproduction http://purl.obolibrary.org/obo/PHIPO_0000043 abnormal reproduction phenotype A single species phenotype where the asexual reproduction process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is abnormal (GO:0019954). http://purl.obolibrary.org/obo/PHIPO_0000048 abnormal sexual reproduction http://purl.obolibrary.org/obo/PHIPO_0000043 abnormal reproduction phenotype A single species phenotype where the sexual reproduction process in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is abnormal (GO:0019953). http://purl.obolibrary.org/obo/PHIPO_0000049 increased number of sexual spores http://purl.obolibrary.org/obo/PHIPO_0000073 abnormal number of sexual spores A population phenotype in which the frequency of occurrence of sexual spores is increased. http://purl.obolibrary.org/obo/PHIPO_0000050 decreased number of sexual spores http://purl.obolibrary.org/obo/PHIPO_0000073 abnormal number of sexual spores A population phenotype in which the frequency of occurrence of sexual spores is decreased. http://purl.obolibrary.org/obo/PHIPO_0000051 increased number of asexual spores http://purl.obolibrary.org/obo/PHIPO_0000082 abnormal number of asexual spores A population phenotype in which the frequency of occurrence of asexual spores is increased. http://purl.obolibrary.org/obo/PHIPO_0000052 decreased number of asexual spores http://purl.obolibrary.org/obo/PHIPO_0000082 abnormal number of asexual spores A population phenotype in which the frequency of occurrence of asexual spores is decreased. http://purl.obolibrary.org/obo/PHIPO_0000053 delayed asexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000078 abnormal asexual sporulation A reproductive phenotype in which the occurrence of asexual spore formation happens later than normal. http://purl.obolibrary.org/obo/PHIPO_0000054 premature asexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000078 abnormal asexual sporulation A reproductive phenotype in which the occurrence of asexual spore formation happens sooner than normal. http://purl.obolibrary.org/obo/PHIPO_0000055 delayed sexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000077 abnormal sexual sporulation A reproductive phenotype in which the occurrence of sexual spore formation happens later than normal. http://purl.obolibrary.org/obo/PHIPO_0000056 premature sexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000077 abnormal sexual sporulation A reproductive phenotype in which the occurrence of sexual spore formation happens sooner than normal. http://purl.obolibrary.org/obo/PHIPO_0000057 normal number of sexual spores http://purl.obolibrary.org/obo/PHIPO_0000079 normal sexual sporulation A population phenotype in which the frequency of occurrence of sexual spores is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000059 normal number of asexual spores http://purl.obolibrary.org/obo/PHIPO_0000080 normal asexual sporulation A population phenotype in which the frequency of occurrence of asexual spores is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000061 asexual spores absent http://purl.obolibrary.org/obo/PHIPO_0000082 abnormal number of asexual spores A reproductive phenotype where asexual spores are absent (FAO:0000023). http://purl.obolibrary.org/obo/PHIPO_0000062 sexual spores absent http://purl.obolibrary.org/obo/PHIPO_0000077 abnormal sexual sporulation A reproductive phenotype where sexual spores are absent (FAO:0000017). http://purl.obolibrary.org/obo/PHIPO_0000063 sexual spores present http://purl.obolibrary.org/obo/PHIPO_0000079 normal sexual sporulation A reproductive phenotype where asexual spores are present (FAO:0000017). The product of meiosis. http://purl.obolibrary.org/obo/PHIPO_0000064 asexual spores present http://purl.obolibrary.org/obo/PHIPO_0000080 normal asexual sporulation A reproductive phenotype where asexual spores are present (FAO:0000023). The product of mitosis. http://purl.obolibrary.org/obo/PHIPO_0000065 asexual spores increased in size http://purl.obolibrary.org/obo/PHIPO_0000081 abnormal asexual spore size A reproductive morphology phenotype where the size of the asexual spore is increased. http://purl.obolibrary.org/obo/PHIPO_0000067 asexual spores decreased in size http://purl.obolibrary.org/obo/PHIPO_0000081 abnormal asexual spore size A reproductive morphology phenotype where the size of the asexual spore is decreased. http://purl.obolibrary.org/obo/PHIPO_0000068 sexual spores increased in size http://purl.obolibrary.org/obo/PHIPO_0000071 abnormal sexual spore size A reproductive morphology phenotype where the size of the sexual spore is increased. http://purl.obolibrary.org/obo/PHIPO_0000069 sexual spores decreased in size http://purl.obolibrary.org/obo/PHIPO_0000071 abnormal sexual spore size A reproductive morphology phenotype where the size of the sexual spore is decreased. http://purl.obolibrary.org/obo/PHIPO_0000070 altered in pigment accumulation in sexual spore http://purl.obolibrary.org/obo/PHIPO_0000285 abnormal cellular pigment accumulation A single species individual organism phenotype where the accumulation of coloring matter in a sexual spore cell is altered. http://purl.obolibrary.org/obo/PHIPO_0000071 abnormal sexual spore size http://purl.obolibrary.org/obo/PHIPO_0000130 abnormal sexual spore morphology A reproductive morphology phenotype where the size of the sexual spore is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000072 abnormal sexual spore shape http://purl.obolibrary.org/obo/PHIPO_0000130 abnormal sexual spore morphology A reproductive morphology phenotype where the shape of the sexual spore is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000073 abnormal number of sexual spores http://purl.obolibrary.org/obo/PHIPO_0000077 abnormal sexual sporulation A population phenotype in which the frequency of occurrence of sexual spores is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000075 abnormal asexual spore shape http://purl.obolibrary.org/obo/PHIPO_0000127 abnormal asexual spore morphology A reproductive morphology phenotype where the shape of the asexual spore is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000076 altered in pigment accumulation in asexual spore http://purl.obolibrary.org/obo/PHIPO_0000285 abnormal cellular pigment accumulation A single species individual organism phenotype where the accumulation of coloring matter in an asexual spore cell is altered. http://purl.obolibrary.org/obo/PHIPO_0000077 abnormal sexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000048 abnormal sexual reproduction A reproductive phenotype where the process of sexual sporulation, the formation of spores from the products of meiosis, is abnormal (GO:0034293). http://purl.obolibrary.org/obo/PHIPO_0000078 abnormal asexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000047 abnormal asexual reproduction A reproductive phenotype where the process of asexual sporulation, the formation of spores derived from the products of an asexual cell division, is abnormal (GO:0030436). http://purl.obolibrary.org/obo/PHIPO_0000079 normal sexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000046 normal sexual reproduction A reproductive phenotype where the process of sexual sporulation, the formation of spores from the products of meiosis, is normal (GO:0034293). http://purl.obolibrary.org/obo/PHIPO_0000080 normal asexual sporulation http://purl.obolibrary.org/obo/PHIPO_0000045 normal asexual reproduction A reproductive phenotype where the process of asexual sporulation, the formation of spores derived from the products of an asexual cell division, is normal (GO:0030436). http://purl.obolibrary.org/obo/PHIPO_0000081 abnormal asexual spore size http://purl.obolibrary.org/obo/PHIPO_0000127 abnormal asexual spore morphology A reproductive morphology phenotype where the size of the asexual spore is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000082 abnormal number of asexual spores http://purl.obolibrary.org/obo/PHIPO_0000078 abnormal asexual sporulation A population phenotype in which the frequency of occurrence of asexual spores is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000096 abnormal meiosis II http://purl.obolibrary.org/obo/PHIPO_0000981 abnormal meiosis A reproductive process phenotype in which the second meiotic nuclear division is abnormal (GO:0007135). http://purl.obolibrary.org/obo/PHIPO_0000097 abnormal meiosis I http://purl.obolibrary.org/obo/PHIPO_0000981 abnormal meiosis A reproductive process phenotype in which the first meiotic nuclear division is abnormal (GO:0007127). http://purl.obolibrary.org/obo/PHIPO_0000098 normal meiosis II http://purl.obolibrary.org/obo/PHIPO_0000982 normal meiosis A reproductive process phenotype in which the second meiotic nuclear division is normal (i.e. indistinguishable from wild type)(GO:0007135). http://purl.obolibrary.org/obo/PHIPO_0000099 normal meiosis I http://purl.obolibrary.org/obo/PHIPO_0000982 normal meiosis A reproductive process phenotype in which the first meiotic nuclear division is normal (GO:0007127). http://purl.obolibrary.org/obo/PHIPO_0000104 increased size of penetration structure http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure A single species pathogen growth phenotype in which the size of pathogen penetration stuctures are increased when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000105 decreased size of penetration structure http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure A single species pathogen growth phenotype in which the size of pathogen penetration stuctures are decreased when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000106 increased number of penetration structure http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration stuctures are increased when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000107 decreased number of penetration structure http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration stuctures are decreased when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000108 delayed timing of penetration structure formation http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure A single species pathogen growth phenotype in which formation of pathogen specialized penetration structure begins later than normal when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000109 premature penetration structure formation http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure A single species pathogen growth phenotype in which formation of pathogen specialized penetration structure begins sooner than normal when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000110 abolished formation of pathogen penetration structure http://purl.obolibrary.org/obo/PHIPO_0000032 abnormal formation of pathogen penetration structure A single species pathogen growth phenotype in which the ability of the pathogen to form a specialized penetration structure is abolished when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000111 delayed pathogen penetration across the barrier http://purl.obolibrary.org/obo/PHIPO_0000024 pathogen penetration across the barrier present A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration begins later than normal when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000114 increased pathogen penetration across the barrier http://purl.obolibrary.org/obo/PHIPO_0000024 pathogen penetration across the barrier present A single species pathogen penetration phenotype in which the frequency of occurrence of pathogen penetration of a given experimental substance/membrane is increased. http://purl.obolibrary.org/obo/PHIPO_0000115 decreased pathogen penetration across the barrier http://purl.obolibrary.org/obo/PHIPO_0000024 pathogen penetration across the barrier present A single species pathogen penetration phenotype in which the frequency of occurrence of pathogen penetration of a given experimental substance/membrane is decreased http://purl.obolibrary.org/obo/PHIPO_0000116 abolished pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000031 abnormal pathogen growth after penetration of the barrier A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is abolished. http://purl.obolibrary.org/obo/PHIPO_0000117 increased pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000031 abnormal pathogen growth after penetration of the barrier A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay is increased. http://purl.obolibrary.org/obo/PHIPO_0000118 decreased pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000031 abnormal pathogen growth after penetration of the barrier A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay is decreased. http://purl.obolibrary.org/obo/PHIPO_0000119 delayed timing of pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000031 abnormal pathogen growth after penetration of the barrier A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay begins later than normal. http://purl.obolibrary.org/obo/PHIPO_0000120 premature pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000031 abnormal pathogen growth after penetration of the barrier A single species phenotype in which the frequency of occurrence of pathogen growth after penetration of a given experimental substance/membrane in an in vitro assay begins sooner than normal. http://purl.obolibrary.org/obo/PHIPO_0000121 abnormal asexual reproductive structure development http://purl.obolibrary.org/obo/PHIPO_0000043 abnormal reproduction phenotype A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is abnormal (GO:0048608). http://purl.obolibrary.org/obo/PHIPO_0000122 abnormal endospore formation http://purl.obolibrary.org/obo/PHIPO_0000078 abnormal asexual sporulation A reproductive phenotype where the process of endospore formation, in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell is abnormal. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. (GO:0034301) http://purl.obolibrary.org/obo/PHIPO_0000126 premature pathogen penetration across the barrier http://purl.obolibrary.org/obo/PHIPO_0000024 pathogen penetration across the barrier present A single species pathogen growth phenotype in which the frequency of occurrence of pathogen penetration begins sooner than normal when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000127 abnormal asexual spore morphology http://purl.obolibrary.org/obo/PHIPO_0000047 abnormal asexual reproduction A reproductive phenotype where the morphology of the asexual spore is abnormal (FAO:0000023). The product of mitosis. http://purl.obolibrary.org/obo/PHIPO_0000128 normal asexual spore morphology http://purl.obolibrary.org/obo/PHIPO_0000045 normal asexual reproduction A reproductive phenotype where the morphology of the asexual spore is normal (FAO:0000023). The product of mitosis. http://purl.obolibrary.org/obo/PHIPO_0000129 normal asexual reproductive structure development http://purl.obolibrary.org/obo/PHIPO_0000045 normal asexual reproduction A single species phenotype where the asexual reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals, from their formation to the mature structures is normal (GO:0048608). http://purl.obolibrary.org/obo/PHIPO_0000130 abnormal sexual spore morphology http://purl.obolibrary.org/obo/PHIPO_0000048 abnormal sexual reproduction A reproductive phenotype where the morphology of the sexual spore is abnormal (FAO:0000017). The product of meiosis. http://purl.obolibrary.org/obo/PHIPO_0000131 pathogen host protein-protein interaction phenotype http://purl.obolibrary.org/obo/PHIPO_0000164 pathogen host interaction binding phenotype A pathogen host interaction phenotype which affects the binding of one pathogen protein to one host protein. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000132 protein-protein interaction phenotype http://purl.obolibrary.org/obo/PHIPO_0000158 binding phenotype A single species phenotype that affects the binding of one protein to another. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000413 abnormal molecular function A single species molecular function phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000134 normal protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000132 protein-protein interaction phenotype A single species molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000135 abolished protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction A single species molecular function phenotype in which the binding of one protein to another does not occur. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000136 decreased protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction A single species molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000137 increased protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction A single species molecular function phenotype in which the binding of one protein to another occurs to a greater extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000138 altered protein binding specificity http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction A single species molecular function phenotype in which a mutation causes a gene product to bind to one or more proteins with different specificity from normal. For example, a protein may bind to a protein in a mutant that it does not bind in wild type. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000139 abnormal protein complex binding http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction A single species molecular function phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000140 decreased duration of protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction A single species molecular function phenotype in which the binding of one protein to another occurs for a shorter time than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000141 decreased extent and duration of protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0000133 abnormal protein-protein interaction A single species molecular function phenotype in which the binding of one protein to another occurs to a lower extent, and for a shorter time, than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000142 RNA binding phenotype http://purl.obolibrary.org/obo/PHIPO_0000158 binding phenotype A single organism phenotype that affects RNA binding. The relevant gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000143 DNA binding phenotype http://purl.obolibrary.org/obo/PHIPO_0000158 binding phenotype A single organism phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000144 normal protein complex binding http://purl.obolibrary.org/obo/PHIPO_0000134 normal protein-protein interaction A single species molecular function phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000145 abnormal DNA binding http://purl.obolibrary.org/obo/PHIPO_0000413 abnormal molecular function A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000146 normal DNA binding http://purl.obolibrary.org/obo/PHIPO_0000143 DNA binding phenotype A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000147 abolished DNA binding http://purl.obolibrary.org/obo/PHIPO_0000145 abnormal DNA binding A single organism (molecular function??) phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000148 altered DNA binding specificity http://purl.obolibrary.org/obo/PHIPO_0000145 abnormal DNA binding A single organism (molecular function??) phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000149 decreased DNA binding http://purl.obolibrary.org/obo/PHIPO_0000145 abnormal DNA binding A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000150 increased DNA binding http://purl.obolibrary.org/obo/PHIPO_0000145 abnormal DNA binding A single organism (molecular function??) phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000151 abnormal multiple protein binding to DNA http://purl.obolibrary.org/obo/PHIPO_0000145 abnormal DNA binding A single organism (molecular function??) phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000152 abnormal RNA binding http://purl.obolibrary.org/obo/PHIPO_0000413 abnormal molecular function A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is abnormal, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000153 normal RNA binding http://purl.obolibrary.org/obo/PHIPO_0000142 RNA binding phenotype A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000154 abolished RNA binding http://purl.obolibrary.org/obo/PHIPO_0000152 abnormal RNA binding A single organism (molecular function??) phenotype in which RNA binding by a gene product does not occur, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000155 decreased RNA binding http://purl.obolibrary.org/obo/PHIPO_0000152 abnormal RNA binding A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is decreased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000156 increased RNA binding http://purl.obolibrary.org/obo/PHIPO_0000152 abnormal RNA binding A single organism (molecular function??) phenotype in which occurrence of RNA binding by a gene product is increased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000158 binding phenotype http://purl.obolibrary.org/obo/PHIPO_0000411 molecular function phenotype A single species phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000159 normal subcellular component http://purl.obolibrary.org/obo/PHIPO_0000463 subcellular component phenotype A single species phenotype in which the amount, distribution, composition or morphology of a cell part is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000160 pathogen penetration across barrier phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A single species phenotype which affects the pathogen's ability to penetrate a given experimental substance/membrane in an in vitro assay. http://purl.obolibrary.org/obo/PHIPO_0000161 reproductive phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A single species phenotype which affects the reproductive process. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). http://purl.obolibrary.org/obo/PHIPO_0000162 unicellular population growth phenotype http://purl.obolibrary.org/obo/PHIPO_0000509 population phenotype A single species population growth phenotype that affects the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction). http://purl.obolibrary.org/obo/PHIPO_0000164 pathogen host interaction binding phenotype http://purl.obolibrary.org/obo/PHIPO_0000347 pathogen host interaction molecular function phenotype A pathogen host interaction phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000173 abolished filamentous growth on host surface http://purl.obolibrary.org/obo/PHIPO_0000350 absence of pathogen growth on host surface A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is abolished (it was present and is now absent). http://purl.obolibrary.org/obo/PHIPO_0000182 absence of host-defense induced lesion by host hypersensitive response http://purl.obolibrary.org/obo/PHIPO_0000481 absence of pathogen-associated host lesions A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense, is absent. http://purl.obolibrary.org/obo/PHIPO_0000188 pathogen growth on host surface phenotype http://purl.obolibrary.org/obo/PHIPO_0000332 pathogen colonization of host phenotype A pathogen colonization of host phenotype which affects the vegetative growth or proliferation of the pathogen on the host surface. http://purl.obolibrary.org/obo/PHIPO_0000190 delayed host-defense induced lesion formation by host hypersensitive response http://purl.obolibrary.org/obo/PHIPO_0000985 decreased extent of pathogen-associated host lesions A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense is delayed. http://purl.obolibrary.org/obo/PHIPO_0000192 presence of host-defense induced lesion by host hypersensitive response http://purl.obolibrary.org/obo/PHIPO_0000461 presence of pathogen-associated host defense induced lesions A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense, is present. http://purl.obolibrary.org/obo/PHIPO_0000196 normal aerial height of filament http://purl.obolibrary.org/obo/PHIPO_0001210 normal hyphal growth An individual organism growth phenotype in which the aerial height of hyphae is normal (indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000200 host chlorosis phenotype in presence of pathogen http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen-host interaction phenotype in which leaves produce insufficient chlorophyll. http://purl.obolibrary.org/obo/PHIPO_0000205 decreased aerial height of filament http://purl.obolibrary.org/obo/PHIPO_0001212 decreased hyphal growth An individual organism growth phenotype in which the aerial height of hyphae is decreased. http://purl.obolibrary.org/obo/PHIPO_0000207 loss of mutualism http://purl.obolibrary.org/obo/PHIPO_0000040 abnormal mutualism A phenotype in which the balance of symbiotic mutualism has been disrupted compared to the normal interaction and the endosymbiont organism is able to show greater biomass within the host and/or the formation of visible disease formation symptoms compared to the normal interaction. http://purl.obolibrary.org/obo/PHIPO_0000212 decreased pathogen host protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0001106 presence of pathogen host protein-protein interaction A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a lesser extent than normal. http://purl.obolibrary.org/obo/PHIPO_0000213 host chlorosis absent in presence of pathogen http://purl.obolibrary.org/obo/PHIPO_0000200 host chlorosis phenotype in presence of pathogen A pathogen-host interaction phenotype in which host chlorosis is absent. http://purl.obolibrary.org/obo/PHIPO_0000214 increased pathogen host protein-protein interaction http://purl.obolibrary.org/obo/PHIPO_0001106 presence of pathogen host protein-protein interaction A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a greater extent than normal. http://purl.obolibrary.org/obo/PHIPO_0000215 host chlorosis present in presence of pathogen http://purl.obolibrary.org/obo/PHIPO_0000200 host chlorosis phenotype in presence of pathogen A pathogen-host interaction phenotype in which host chlorosis is present. http://purl.obolibrary.org/obo/PHIPO_0000219 decreased level of pathogen deoxynivalenol within host http://purl.obolibrary.org/obo/PHIPO_0001045 decreased level of pathogen produced toxin within host A pathogen host interaction phenotype, in which the level of pathogen produced deoxynivalenol usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0000232 increased level of pathogen deoxynivalenol within host http://purl.obolibrary.org/obo/PHIPO_0001046 increased level of pathogen produced toxin within host A pathogen host interaction phenotype, in which the level of pathogen produced deoxynivalenol usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0000233 pathogen deoxynivalenol within host present http://purl.obolibrary.org/obo/PHIPO_0001043 level of pathogen produced toxin within host phenotype A pathogen host interaction phenotype, in which the pathogen produced deoxynivalenol usually present during infection is present as normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000234 pathogen deoxynivalenol within host absent http://purl.obolibrary.org/obo/PHIPO_0001047 pathogen toxin within host absent A pathogen host interaction phenotype, in which the pathogen produced deoxynivalenol usually present during infection is absent or at a level too low to detect. http://purl.obolibrary.org/obo/PHIPO_0000235 localization phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A single species phenotype that affects the localization of a structure or substance in a cell. http://purl.obolibrary.org/obo/PHIPO_0000236 pathogen host interaction localization phenotype http://purl.obolibrary.org/obo/PHIPO_0000510 pathogen host interaction cell phenotype A pathogen host interaction phenotype that affects the localization of a structure or substance in a cell. http://purl.obolibrary.org/obo/PHIPO_0000237 protein localization phenotype http://purl.obolibrary.org/obo/PHIPO_0000235 localization phenotype A single organism phenotype that affects the localization of a protein in a cell. http://purl.obolibrary.org/obo/PHIPO_0000239 abnormal protein localization http://purl.obolibrary.org/obo/PHIPO_0001094 abnormal localization A single organism phenotype in which the localization of a protein in a cell is abnormal. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. http://purl.obolibrary.org/obo/PHIPO_0000240 abnormal pathogen protein localization within host http://purl.obolibrary.org/obo/PHIPO_0000236 pathogen host interaction localization phenotype A pathogen host interaction phenotype, in which the localization of a pathogen protein in a host cell differs from normal. http://purl.obolibrary.org/obo/PHIPO_0000241 abnormal protein complex localization http://purl.obolibrary.org/obo/PHIPO_0000239 abnormal protein localization A single organism phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000244 abnormal protein localization to nucleus http://purl.obolibrary.org/obo/PHIPO_0000239 abnormal protein localization A single organism phenotype in which the localization of a protein to the nucleus is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000245 abolished protein localization http://purl.obolibrary.org/obo/PHIPO_0000239 abnormal protein localization A single organism phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found. http://purl.obolibrary.org/obo/PHIPO_0000246 abolished pathogen protein localization within host http://purl.obolibrary.org/obo/PHIPO_0000240 abnormal pathogen protein localization within host A pathogen host interaction phenotype in which the localization of a pathogen protein to a host structure or compartment is abolished (i.e. the protein was localized to the host structure or compartment and now is not). http://purl.obolibrary.org/obo/PHIPO_0000247 abolished pathogen protein localization to host nucleus http://purl.obolibrary.org/obo/PHIPO_0000246 abolished pathogen protein localization within host A pathogen host interaction phenotype in which the localization of a pathogen protein to the host nucleus is abolished. http://purl.obolibrary.org/obo/PHIPO_0000248 abolished protein localization to nucleus http://purl.obolibrary.org/obo/PHIPO_0000245 abolished protein localization A single organism phenotype in which the localization of a protein to the nucleus is abolished (GO:0034504). http://purl.obolibrary.org/obo/PHIPO_0000249 RNA localization phenotype http://purl.obolibrary.org/obo/PHIPO_0000235 localization phenotype A single organism phenotype that affects the localization of an RNA in a cell. http://purl.obolibrary.org/obo/PHIPO_0000251 abnormal RNA localization http://purl.obolibrary.org/obo/PHIPO_0001094 abnormal localization A single organism phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. http://purl.obolibrary.org/obo/PHIPO_0000253 normal RNA localization http://purl.obolibrary.org/obo/PHIPO_0000249 RNA localization phenotype A single organism phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000256 transport phenotype http://purl.obolibrary.org/obo/PHIPO_0000235 localization phenotype A single organism cell phenotype that affects a transport process. http://purl.obolibrary.org/obo/PHIPO_0000257 abnormal transport http://purl.obolibrary.org/obo/PHIPO_0001094 abnormal localization A single organism phenotype in which a specific transport process is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000259 normal protein transport http://purl.obolibrary.org/obo/PHIPO_0000256 transport phenotype A single organism cellular process phenotype in which protein transport is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000261 abnormal endocytosis http://purl.obolibrary.org/obo/PHIPO_0000257 abnormal transport A single organism cellular process phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. http://purl.obolibrary.org/obo/PHIPO_0000263 abnormal nuclear transport http://purl.obolibrary.org/obo/PHIPO_0000257 abnormal transport A single organism cellular process phenotype in which nuclear transport is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000265 abnormal protein transport http://purl.obolibrary.org/obo/PHIPO_0000257 abnormal transport A single organism cellular process phenotype in which protein transport is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000267 abnormal vacuolar transport http://purl.obolibrary.org/obo/PHIPO_0000257 abnormal transport A single organism cellular process phenotype in which vacuolar transport is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000269 normal protein localization http://purl.obolibrary.org/obo/PHIPO_0000237 protein localization phenotype A single organism phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000270 normal pathogen protein and host protein colocalization within host http://purl.obolibrary.org/obo/PHIPO_0000236 pathogen host interaction localization phenotype A pathogen host interaction phenotype, in which the colocalization of a pathogen protein and a host protein within a host cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000271 normal protein localization to nucleus http://purl.obolibrary.org/obo/PHIPO_0000269 normal protein localization A single organism phenotype in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type)(GO:0034504). http://purl.obolibrary.org/obo/PHIPO_0000272 normal pathogen protein localization to host nucleus http://purl.obolibrary.org/obo/PHIPO_0001175 normal pathogen protein localization within host A pathogen host interaction phenotype in which the localization of a pathogen protein to the host nucleus is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000274 increased asexual spore germination frequency http://purl.obolibrary.org/obo/PHIPO_0000509 population phenotype A population phenotype in which the frequency of occurrence of asexual spore germination is increased. http://purl.obolibrary.org/obo/PHIPO_0000275 abnormal tissue phenotype http://purl.obolibrary.org/obo/PHIPO_0000003 tissue phenotype A phenotype that shows detectable differences from normal at the level of a tissue (eg leaf, inflorescence, ear or kidney). http://purl.obolibrary.org/obo/PHIPO_0000276 normal tissue phenotype http://purl.obolibrary.org/obo/PHIPO_0000003 tissue phenotype A phenotype that does not show any detectable differences from normal at the level of a tissue (eg leaf, inflorescence, ear or kidney). http://purl.obolibrary.org/obo/PHIPO_0000280 pathogen effector mediated modulation of host immune system process http://purl.obolibrary.org/obo/PHIPO_0001167 pathogen modulation of host immune system process phenotype A phenotype dependent on an interaction between a pathogen effector and a host process in order for the pathogen to activate or suppress the host immune system. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses. http://purl.obolibrary.org/obo/PHIPO_0000284 pigment phenotype http://purl.obolibrary.org/obo/PHIPO_0000402 individual organism phenotype A single species individual organism phenotype affecting the deposition or aggregation of coloring matter in a cell. http://purl.obolibrary.org/obo/PHIPO_0000285 abnormal cellular pigment accumulation http://purl.obolibrary.org/obo/PHIPO_0000284 pigment phenotype A single species individual organism phenotype where the accumulation of coloring matter in a cell is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000286 normal cellular pigment accumulation http://purl.obolibrary.org/obo/PHIPO_0000284 pigment phenotype A single species individual organism phenotype where the accumulation of coloring matter in a cell is normal. http://purl.obolibrary.org/obo/PHIPO_0000287 increased cellular pigment accumulation http://purl.obolibrary.org/obo/PHIPO_0000285 abnormal cellular pigment accumulation A single species individual organism phenotype where the accumulation of coloring matter in a cell is increased. http://purl.obolibrary.org/obo/PHIPO_0000288 decreased cellular pigment accumulation http://purl.obolibrary.org/obo/PHIPO_0000285 abnormal cellular pigment accumulation A single species individual organism phenotype where the accumulation of coloring matter in a cell is decreased. http://purl.obolibrary.org/obo/PHIPO_0000292 decreased filament length http://purl.obolibrary.org/obo/PHIPO_0001205 abnormal filament morphology A single species cell morphology phenotype where hyphal filaments are short in length. http://purl.obolibrary.org/obo/PHIPO_0000295 sinusoidal filament http://purl.obolibrary.org/obo/PHIPO_0001205 abnormal filament morphology A single species cell morphology phenotype where hyphal filaments are wavy. http://purl.obolibrary.org/obo/PHIPO_0000300 abnormal dissemination of asexual spore http://purl.obolibrary.org/obo/PHIPO_0000043 abnormal reproduction phenotype A single species phenotype where the dispersal of asexual spores is abnormal (FAO:0000023). http://purl.obolibrary.org/obo/PHIPO_0000301 normal dissemination of asexual spore http://purl.obolibrary.org/obo/PHIPO_0000044 normal reproduction phenotype A single species phenotype where the dispersal of asexual spores is normal (FAO:0000023). http://purl.obolibrary.org/obo/PHIPO_0000302 normal dissemination of sexual spore http://purl.obolibrary.org/obo/PHIPO_0000044 normal reproduction phenotype A single species phenotype where the dispersal of sexual spores is normal (FAO:0000017). http://purl.obolibrary.org/obo/PHIPO_0000303 abnormal dissemination of sexual spore http://purl.obolibrary.org/obo/PHIPO_0000043 abnormal reproduction phenotype A single species phenotype where the dispersal of sexual spores is abnormal (FAO:0000017). http://purl.obolibrary.org/obo/PHIPO_0000327 resistance to cyproconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to cypronazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000328 normal cellular component organization http://purl.obolibrary.org/obo/PHIPO_0000407 cellular component organization phenotype A cellular process phenotype in which any process of cellular component organization at the cellular level is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000329 sensitive to cyproconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to cyproconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000330 abnormal transporter activity http://purl.obolibrary.org/obo/PHIPO_0000413 abnormal molecular function A molecular function phenotype in which the observed rate of a specified transporter activity is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000331 pathogen penetration into host present http://purl.obolibrary.org/obo/PHIPO_0000949 pathogen entry into host phenotype A pathogen entry into host phenotype in which pathogen penetration into the body, tissues, or cells of the host organism is present. http://purl.obolibrary.org/obo/PHIPO_0000332 pathogen colonization of host phenotype http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype which affects the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0000333 pathogen cell to cell migration within host phenotype http://purl.obolibrary.org/obo/PHIPO_0000332 pathogen colonization of host phenotype A pathogen host interaction colonization phenotype which affects the directional movement of the pathogen within the host organism (GO:0044001). http://purl.obolibrary.org/obo/PHIPO_0000334 abnormal pathogen cell to cell migration within host http://purl.obolibrary.org/obo/PHIPO_0000333 pathogen cell to cell migration within host phenotype A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000335 normal pathogen cell to cell migration within host http://purl.obolibrary.org/obo/PHIPO_0000333 pathogen cell to cell migration within host phenotype A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is normal. http://purl.obolibrary.org/obo/PHIPO_0000338 increased pathogen cell to cell migration within host http://purl.obolibrary.org/obo/PHIPO_0000334 abnormal pathogen cell to cell migration within host A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is increased compared to normal. http://purl.obolibrary.org/obo/PHIPO_0000339 decreased pathogen cell to cell migration within host http://purl.obolibrary.org/obo/PHIPO_0000334 abnormal pathogen cell to cell migration within host A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism is decreased compared to normal. http://purl.obolibrary.org/obo/PHIPO_0000340 abolished pathogen cell to cell migration within host http://purl.obolibrary.org/obo/PHIPO_0000334 abnormal pathogen cell to cell migration within host A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally within the host organism is abolished (pathogen migration was present within the host and is now absent). http://purl.obolibrary.org/obo/PHIPO_0000342 premature pathogen cell to cell migration within host http://purl.obolibrary.org/obo/PHIPO_0000334 abnormal pathogen cell to cell migration within host A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism happens sooner than normal. http://purl.obolibrary.org/obo/PHIPO_0000343 delayed pathogen cell to cell migration within host http://purl.obolibrary.org/obo/PHIPO_0000334 abnormal pathogen cell to cell migration within host A pathogen host interaction colonization phenotype in which the occurrence of the directional movement of the pathogen within the host organism happens later than normal. http://purl.obolibrary.org/obo/PHIPO_0000347 pathogen host interaction molecular function phenotype http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype that affects a molecular function such as binding or catalytic activity. http://purl.obolibrary.org/obo/PHIPO_0000349 presence of pathogen growth on host surface http://purl.obolibrary.org/obo/PHIPO_0000188 pathogen growth on host surface phenotype A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is present. http://purl.obolibrary.org/obo/PHIPO_0000350 absence of pathogen growth on host surface http://purl.obolibrary.org/obo/PHIPO_0000188 pathogen growth on host surface phenotype A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is absent. http://purl.obolibrary.org/obo/PHIPO_0000352 normal formation of pathogen penetration structure prior to entry into host http://purl.obolibrary.org/obo/PHIPO_0000949 pathogen entry into host phenotype A pathogen growth with host phenotype in which the formation of the pathogen penetration structure is normal (i.e indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000355 pathogen penetration into host absent http://purl.obolibrary.org/obo/PHIPO_0000949 pathogen entry into host phenotype A pathogen entry into host phenotype in which pathogen penetration into the body, tissues, or cells of the host organism is absent. http://purl.obolibrary.org/obo/PHIPO_0000359 decreased pathogen penetration into host http://purl.obolibrary.org/obo/PHIPO_0000331 pathogen penetration into host present A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism is decreased. http://purl.obolibrary.org/obo/PHIPO_0000360 increased pathogen penetration into host http://purl.obolibrary.org/obo/PHIPO_0000331 pathogen penetration into host present A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism is increased. http://purl.obolibrary.org/obo/PHIPO_0000361 delayed pathogen penetration into host http://purl.obolibrary.org/obo/PHIPO_0000331 pathogen penetration into host present A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism begins later than normal. http://purl.obolibrary.org/obo/PHIPO_0000362 premature pathogen penetration into host http://purl.obolibrary.org/obo/PHIPO_0000331 pathogen penetration into host present A pathogen entry into host phenotype in which the frequency of occurrence of pathogen penetration into the body, tissues, or cells of the host organism begins sooner than normal. http://purl.obolibrary.org/obo/PHIPO_0000363 absence of pathogen growth within host http://purl.obolibrary.org/obo/PHIPO_0000951 pathogen growth within host phenotype A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is absent. http://purl.obolibrary.org/obo/PHIPO_0000365 decreased pathogen growth within host http://purl.obolibrary.org/obo/PHIPO_0000954 presence of pathogen growth within host A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host is decreased. http://purl.obolibrary.org/obo/PHIPO_0000366 delayed timing of pathogen growth within host http://purl.obolibrary.org/obo/PHIPO_0000954 presence of pathogen growth within host A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host begins later than normal. http://purl.obolibrary.org/obo/PHIPO_0000367 premature pathogen growth within host http://purl.obolibrary.org/obo/PHIPO_0000954 presence of pathogen growth within host A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host begins sooner than normal. http://purl.obolibrary.org/obo/PHIPO_0000368 increased pathogen growth within host http://purl.obolibrary.org/obo/PHIPO_0000954 presence of pathogen growth within host A pathogen host phenotype in which the frequency of occurrence of vegetative growth or proliferation of the pathogen inside the host is increased. http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host http://purl.obolibrary.org/obo/PHIPO_0000949 pathogen entry into host phenotype A pathogen growth with host phenotype in which the formation of the pathogen penetration structure is abnormal (i.e different than wild-type). http://purl.obolibrary.org/obo/PHIPO_0000371 decreased number of pathogen penetration structure when near host http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host A pathogen growth with host phenotype in which the frequency of occurrence of pathogen penetration stuctures near the host are decreased. http://purl.obolibrary.org/obo/PHIPO_0000372 decreased size of pathogen penetration structure when near host http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host A pathogen growth with host phenotype in which the size of pathogen penetration stuctures near the host are decreased. http://purl.obolibrary.org/obo/PHIPO_0000373 increased number of pathogen penetration structure when near host http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host A pathogen growth with host phenotype in which the frequency of occurrence of pathogen penetration stuctures near the host are increased. http://purl.obolibrary.org/obo/PHIPO_0000374 increased size of pathogen penetration structure when near host http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host A pathogen growth with host phenotype in which the size of pathogen penetration stuctures near the host are increased. http://purl.obolibrary.org/obo/PHIPO_0000375 delayed timing of pathogen penetration structure formation when near host http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host A pathogen growth with host phenotype in which the formation of pathogen specialized penetration structure begins later than normal. http://purl.obolibrary.org/obo/PHIPO_0000376 premature pathogen penetration structure formation when near host http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host A pathogen growth with host phenotype in which the formation of pathogen specialized penetration structure begins sooner than normal. http://purl.obolibrary.org/obo/PHIPO_0000377 resistance to carboxin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to carboxin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000378 sensitive to carboxin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to carboxin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000379 abnormal cell wall organization http://purl.obolibrary.org/obo/PHIPO_0000400 abnormal cellular component organization A cellular process phenotype in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall. http://purl.obolibrary.org/obo/PHIPO_0000380 normal transporter activity http://purl.obolibrary.org/obo/PHIPO_0000409 transporter activity phenotype A molecular function phenotype in which the observed rate of a specified transporter activity is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000381 resistance to benomyl http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to benomyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000382 resistance to diethofencarb http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to diethofencarb. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000383 resistance to carbendazim http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to carbendazim. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000384 resistance to thiophanate methyl http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to thiophanate methyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000385 resistance to oxolinic acid http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to oxolinic acid. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000386 resistance to naftifine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to naftifine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000387 resistance to terbinafine http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to terbinafine. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000388 resistance to azoxystrobin http://purl.obolibrary.org/obo/PHIPO_0000576 resistance to strobilurin A A growth phenotype which describes the resistance of individuals or populations after exposure to azoxystrobin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000389 resistance to iprodione http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to iprodione. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000390 sensitive to diethofencarb http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to diethocarb. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000391 sensitive to carbendazim http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to carbendazim. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000392 sensitive to thiophanate methyl http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiophanate methyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000393 sensitive to oxolinic acid http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to oxolinic acid. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000394 sensitive to naftifine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to naftifine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000395 sensitive to terbinafine http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to terbinafine. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000396 sensitive to azoxystrobin http://purl.obolibrary.org/obo/PHIPO_0000804 sensitive to strobilurin A A growth phenotype which describes the sensitivity of individuals or populations after exposure to azoxystrobin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000397 sensitive to iprodione http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to iprodione. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000398 sensitive to benomyl http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to benomyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000400 abnormal cellular component organization http://purl.obolibrary.org/obo/PHIPO_0000407 cellular component organization phenotype A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000402 individual organism phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A single species phenotype that is observed at the level of an individual organism. http://purl.obolibrary.org/obo/PHIPO_0000403 normal cell phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A phenotype that does not show any detectable differences from normal at the level of an individual cell. http://purl.obolibrary.org/obo/PHIPO_0000404 abnormal cell phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A phenotype that shows detectable differences from normal at the level of an individual cell. http://purl.obolibrary.org/obo/PHIPO_0000405 normal unicellular population growth http://purl.obolibrary.org/obo/PHIPO_0000162 unicellular population growth phenotype A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000406 nucleus absent http://purl.obolibrary.org/obo/PHIPO_0000934 abnormal nucleus A single organism phenotype in which the nucleus is absent. http://purl.obolibrary.org/obo/PHIPO_0000407 cellular component organization phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A phenotype that affects a process of cellular component organization, i.e. the assembly, arrangement of constituent parts, or disassembly of a cellular component, that occurs at the cellular level. http://purl.obolibrary.org/obo/PHIPO_0000409 transporter activity phenotype http://purl.obolibrary.org/obo/PHIPO_0000411 molecular function phenotype A phenotype that affects a transporter activity. http://purl.obolibrary.org/obo/PHIPO_0000410 decreased asexual spore germination frequency http://purl.obolibrary.org/obo/PHIPO_0000509 population phenotype A population phenotype in which the frequency of occurrence of asexual spore germination is decreased. http://purl.obolibrary.org/obo/PHIPO_0000411 molecular function phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A phenotype that affects a molecular function such as binding or catalytic activity. http://purl.obolibrary.org/obo/PHIPO_0000413 abnormal molecular function http://purl.obolibrary.org/obo/PHIPO_0000411 molecular function phenotype A phenotype in which a specific molecular function is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000414 abnormal unicellular population growth http://purl.obolibrary.org/obo/PHIPO_0000162 unicellular population growth phenotype A single species population growth phenotype where the rate or extent of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is lesser or greater than normal. http://purl.obolibrary.org/obo/PHIPO_0000415 abnormal subcellular component http://purl.obolibrary.org/obo/PHIPO_0000463 subcellular component phenotype A single organism phenotype in which the amount, distribution, composition or morphology of a cell part is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000416 normal molecular function http://purl.obolibrary.org/obo/PHIPO_0000411 molecular function phenotype A phenotype in which a specific molecular function is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000418 normal carbohydrate binding http://purl.obolibrary.org/obo/PHIPO_0000430 carbohydrate binding phenotype A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000419 abnormal carbohydrate binding http://purl.obolibrary.org/obo/PHIPO_0000430 carbohydrate binding phenotype A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000420 normal pathogen chitin fragment binding http://purl.obolibrary.org/obo/PHIPO_0000418 normal carbohydrate binding A single species molecular function phenotype in which occurrence of pathogen chitin fragment binding by a pathogen gene product is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000421 abolished carbohydrate binding http://purl.obolibrary.org/obo/PHIPO_0000419 abnormal carbohydrate binding A single species molecular function phenotype in which carbohydrate binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000422 altered carbohydrate binding specificity http://purl.obolibrary.org/obo/PHIPO_0000419 abnormal carbohydrate binding A single species phenotype in which a gene product that normally binds to a specific carbohydrate instead binds to a different carbohydrate when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000423 decreased carbohydrate binding http://purl.obolibrary.org/obo/PHIPO_0000419 abnormal carbohydrate binding A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000424 increased carbohydrate binding http://purl.obolibrary.org/obo/PHIPO_0000419 abnormal carbohydrate binding A single species molecular function phenotype in which occurrence of carbohydrate binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000430 carbohydrate binding phenotype http://purl.obolibrary.org/obo/PHIPO_0000158 binding phenotype A single species molecular function phenotype that affects carbohydrate binding. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000431 abolished pathogen chitin fragment binding http://purl.obolibrary.org/obo/PHIPO_0000421 abolished carbohydrate binding A single species pathogen molecular function phenotype in which pathogen chitin fragment binding by a pathogen gene product does not occur. (It was present and is now absent). http://purl.obolibrary.org/obo/PHIPO_0000432 catalytic activity phenotype http://purl.obolibrary.org/obo/PHIPO_0000411 molecular function phenotype A single organism phenotype that affects a catalytic activity. http://purl.obolibrary.org/obo/PHIPO_0000433 normal catalytic activity http://purl.obolibrary.org/obo/PHIPO_0000432 catalytic activity phenotype A single species molecular function phenotype in which the observed rate and other catalytic properties of a specified catalytic activity are normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000434 abnormal catalytic activity http://purl.obolibrary.org/obo/PHIPO_0000432 catalytic activity phenotype A single species molecular function phenotype in which the observed rate or other catalytic property of a specified catalytic activity is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000435 abolished catalytic activity http://purl.obolibrary.org/obo/PHIPO_0000434 abnormal catalytic activity A single species molecular function phenotype in which a specified catalytic activity is absent. http://purl.obolibrary.org/obo/PHIPO_0000436 decreased catalytic activity http://purl.obolibrary.org/obo/PHIPO_0000434 abnormal catalytic activity A single species molecular function phenotype in which the observed rate of a specified catalytic activity is decreased. http://purl.obolibrary.org/obo/PHIPO_0000437 increased catalytic activity http://purl.obolibrary.org/obo/PHIPO_0000434 abnormal catalytic activity A single species molecular function phenotype in which the observed rate of a specified catalytic activity is increased. http://purl.obolibrary.org/obo/PHIPO_0000438 altered substrate specificity http://purl.obolibrary.org/obo/PHIPO_0000434 abnormal catalytic activity A single species molecular function phenotype in which the substrate specificity of a catalytic activity differs from wild type. http://purl.obolibrary.org/obo/PHIPO_0000439 pathogen reproductive phenotype within host http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype which affects the pathogen reproductive process within the host. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). http://purl.obolibrary.org/obo/PHIPO_0000440 normal pathogen reproductive phenotype within host http://purl.obolibrary.org/obo/PHIPO_0000439 pathogen reproductive phenotype within host A pathogen host interaction phenotype where the pathogen reproductive process within the host is normal (indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000441 abnormal pathogen reproductive phenotype within host http://purl.obolibrary.org/obo/PHIPO_0000439 pathogen reproductive phenotype within host A pathogen host interaction phenotype where the pathogen reproductive process within the host is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000442 normal pathogen asexual reproduction within host http://purl.obolibrary.org/obo/PHIPO_0000440 normal pathogen reproductive phenotype within host A pathogen reproductive phenotype within host where the pathogen asexual reproduction process, in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is normal (indistinguishable from wild type)(GO:0019954). http://purl.obolibrary.org/obo/PHIPO_0000443 normal pathogen sexual reproduction within host http://purl.obolibrary.org/obo/PHIPO_0000440 normal pathogen reproductive phenotype within host A pathogen reproductive phenotype within host where the pathogen sexual reproduction process, in which new individuals are produced by combining the genetic material of two gametes, which may come from two organisms or from a single organism is normal (indistinguishable from wild type) (GO:0019953). http://purl.obolibrary.org/obo/PHIPO_0000444 decreased number of asexual pathogen spores within host http://purl.obolibrary.org/obo/PHIPO_0000448 abnormal number of asexual pathogen spores within host A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is decreased. http://purl.obolibrary.org/obo/PHIPO_0000445 pathogen host interaction host lesion formation phenotype http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A phenotype that affects the process of host tissue death causing a host lesion induced by either the pathogen directly killing host tissue (e.g. cell wall degradation), or the host activating its own cell death pathways in defense. http://purl.obolibrary.org/obo/PHIPO_0000446 host cell death phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A single species phenotype that affects the cell death within a host. http://purl.obolibrary.org/obo/PHIPO_0000447 increased number of asexual pathogen spores within host http://purl.obolibrary.org/obo/PHIPO_0000448 abnormal number of asexual pathogen spores within host A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is increased. http://purl.obolibrary.org/obo/PHIPO_0000448 abnormal number of asexual pathogen spores within host http://purl.obolibrary.org/obo/PHIPO_0000449 abnormal pathogen asexual reproduction within host A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is abnormal http://purl.obolibrary.org/obo/PHIPO_0000449 abnormal pathogen asexual reproduction within host http://purl.obolibrary.org/obo/PHIPO_0000469 abnormal pathogen asexual sporulation within host A pathogen reproductive phenotype within host where the pathogen asexual reproduction process, in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process is abnormal (GO:0019954). http://purl.obolibrary.org/obo/PHIPO_0000450 normal pathogen peptidase activity http://purl.obolibrary.org/obo/PHIPO_0000433 normal catalytic activity A single species molecular function phenotype in which the observed rate of a peptidase activity is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000461 presence of pathogen-associated host defense induced lesions http://purl.obolibrary.org/obo/PHIPO_0000480 presence of pathogen-associated host lesions A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own programmed cell death pathways in defense, is present. http://purl.obolibrary.org/obo/PHIPO_0000463 subcellular component phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A single organism phenotype that affects the subcellular components in a cell. http://purl.obolibrary.org/obo/PHIPO_0000465 absence of pathogen necrotrophic effector-mediated host programmed cell death http://purl.obolibrary.org/obo/PHIPO_0000481 absence of pathogen-associated host lesions A phenotype where the process of a necrotrophic pathogen effector activating the host immune system to trigger programmed cell death is absent. http://purl.obolibrary.org/obo/PHIPO_0000467 presence of effector-independent host hypersensitive response http://purl.obolibrary.org/obo/PHIPO_0000446 host cell death phenotype A single species phenotype where the immune system process of host tissue hypersensitive response is present in a pathogen effector-independant manner. (i.e. an alteration within the host is responsible for the activation of the hypersensitive response in the absence of a pathogen). http://purl.obolibrary.org/obo/PHIPO_0000468 absence of pathogen asexual spores within host http://purl.obolibrary.org/obo/PHIPO_0000469 abnormal pathogen asexual sporulation within host A pathogen reproductive phenotype within host where the pathogen asexual spores are absent (FAO:0000023). http://purl.obolibrary.org/obo/PHIPO_0000469 abnormal pathogen asexual sporulation within host http://purl.obolibrary.org/obo/PHIPO_0000441 abnormal pathogen reproductive phenotype within host A pathogen reproductive phenotype within host where the process of pathogen asexual sporulation, the formation of spores derived from the products of an asexual cell division, is abnormal (GO:0030436). http://purl.obolibrary.org/obo/PHIPO_0000472 normal pathogen asexual sporulation within host http://purl.obolibrary.org/obo/PHIPO_0000442 normal pathogen asexual reproduction within host A pathogen reproductive phenotype within host where the process of pathogen asexual sporulation, the formation of spores derived from the products of an asexual cell division, is normal (GO:0030436). http://purl.obolibrary.org/obo/PHIPO_0000473 presence of pathogen asexual spores within host http://purl.obolibrary.org/obo/PHIPO_0000472 normal pathogen asexual sporulation within host A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual spores is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000474 abnormal number of lipid droplets http://purl.obolibrary.org/obo/PHIPO_0000478 lipid droplet phenotype A single species phenotype observed in the vegetative growth phase of the life cycle in which cells contain a different number of lipid droplets than normal. http://purl.obolibrary.org/obo/PHIPO_0000475 decreased size of lipid droplet http://purl.obolibrary.org/obo/PHIPO_0000036 abnormal lipid droplet morphology A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size of lipid droplets is decreased. http://purl.obolibrary.org/obo/PHIPO_0000477 presence of pathogen necrotrophic effector-mediated host programmed cell death http://purl.obolibrary.org/obo/PHIPO_0000480 presence of pathogen-associated host lesions A phenotype where the process of a necrotrophic pathogen effector activating the host immune system to trigger programmed cell death is present. http://purl.obolibrary.org/obo/PHIPO_0000478 lipid droplet phenotype http://purl.obolibrary.org/obo/PHIPO_0000415 abnormal subcellular component A single organism phenotype that affects an intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins. http://purl.obolibrary.org/obo/PHIPO_0000479 increased size of lipid droplet http://purl.obolibrary.org/obo/PHIPO_0000036 abnormal lipid droplet morphology A single organism phenotype observed in the vegetative growth phase of the life cycle in which the size of lipid droplets is increased. http://purl.obolibrary.org/obo/PHIPO_0000480 presence of pathogen-associated host lesions http://purl.obolibrary.org/obo/PHIPO_0000445 pathogen host interaction host lesion formation phenotype A phenotype where the process of host tissue cell death causing a host lesion is present. http://purl.obolibrary.org/obo/PHIPO_0000481 absence of pathogen-associated host lesions http://purl.obolibrary.org/obo/PHIPO_0000445 pathogen host interaction host lesion formation phenotype A phenotype where the process of host tissue cell death causing a host lesion is absent. http://purl.obolibrary.org/obo/PHIPO_0000492 metabolic process phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A single organism phenotype that affects the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. http://purl.obolibrary.org/obo/PHIPO_0000493 primary metabolic process phenotype http://purl.obolibrary.org/obo/PHIPO_0000492 metabolic process phenotype A single organism phenotype that affects the chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/PHIPO_0000494 secondary metabolic process phenotype http://purl.obolibrary.org/obo/PHIPO_0000492 metabolic process phenotype A single organism phenotype that affects the chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. http://purl.obolibrary.org/obo/PHIPO_0000495 secondary metabolite biosynthetic process phenotype http://purl.obolibrary.org/obo/PHIPO_0000494 secondary metabolic process phenotype A single organism phenotype that affects the chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. http://purl.obolibrary.org/obo/PHIPO_0000496 toxin biosynthetic process phenotype http://purl.obolibrary.org/obo/PHIPO_0000495 secondary metabolite biosynthetic process phenotype A single organism phenotype that affects the chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. http://purl.obolibrary.org/obo/PHIPO_0000497 normal toxin biosynthetic process http://purl.obolibrary.org/obo/PHIPO_0000496 toxin biosynthetic process phenotype A single organism phenotype in which the toxin biosynthetic process is normal (i.e. same as the wild type). http://purl.obolibrary.org/obo/PHIPO_0000498 abnormal toxin biosynthetic process http://purl.obolibrary.org/obo/PHIPO_0000496 toxin biosynthetic process phenotype A single organism phenotype in which the toxin biosynthetic process is abnormal (i.e. different than the wild type). http://purl.obolibrary.org/obo/PHIPO_0000509 population phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A single species phenotype that is observed at the level of a population. http://purl.obolibrary.org/obo/PHIPO_0000510 pathogen host interaction cell phenotype http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype that is observed at the level of an individual cell. http://purl.obolibrary.org/obo/PHIPO_0000513 inviable population http://purl.obolibrary.org/obo/PHIPO_0000514 population viability phenotype An organism population phenotype in which no organisms in the population are viable. http://purl.obolibrary.org/obo/PHIPO_0000514 population viability phenotype http://purl.obolibrary.org/obo/PHIPO_0000509 population phenotype A single organism cell population phenotype that reflects the proportion of the population that survive and develop normally. http://purl.obolibrary.org/obo/GO_0150111 regulation of transepithelial transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of transepithelial transport. http://purl.obolibrary.org/obo/PHIPO_0000985 decreased extent of pathogen-associated host lesions http://purl.obolibrary.org/obo/PHIPO_0000480 presence of pathogen-associated host lesions A phenotype where the process of host tissue cell death causing a host lesion occurs to a lesser extent than normal. http://purl.obolibrary.org/obo/PHIPO_0000986 increased extent of pathogen-associated host lesions http://purl.obolibrary.org/obo/PHIPO_0000480 presence of pathogen-associated host lesions A phenotype where the process of host tissue cell death causing a host lesion occurs to a greater extent than normal. http://purl.obolibrary.org/obo/PHIPO_0000989 decreased level of pathogen protein within host http://purl.obolibrary.org/obo/PHIPO_0001197 level of pathogen produced substance within host phenotype A pathogen host interaction phenotype, in which the level of pathogen protein usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0000991 increased level of host defense-induced protein http://purl.obolibrary.org/obo/PHIPO_0001262 host defense-induced protein level phenotype A pathogen host interaction phenotype, in which the level of host protein usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0000992 increased expression of a host defense-related protein involved in a pathogen interaction http://purl.obolibrary.org/obo/PHIPO_0000991 increased level of host defense-induced protein A pathogen host interaction phenotype, in which the level of host defense-related protein usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0000995 decreased level of pathogen RNA within host http://purl.obolibrary.org/obo/PHIPO_0001267 level of pathogen produced RNA within host phenotype A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0000998 pathogen morphology phenotype during colonization of host http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype which affects the pathogen morphology during host colonization. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0000999 abnormal pathogen morphology during colonization of host http://purl.obolibrary.org/obo/PHIPO_0000998 pathogen morphology phenotype during colonization of host A pathogen host interaction phenotype where the morphology of the pathogen during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001000 abnormal pathogen swollen terminal hyphae during cell to cell migration http://purl.obolibrary.org/obo/PHIPO_0000999 abnormal pathogen morphology during colonization of host A pathogen host interaction phenotype where the morphology of the pathogen terminal hyphae during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001001 abnormal organization of pathogen septin collar during cell to cell migration http://purl.obolibrary.org/obo/PHIPO_0000999 abnormal pathogen morphology during colonization of host A pathogen host interaction phenotype where the morphology of the pathogen septin collar (GO:0032173) during host colonization is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001002 host morphology phenotype during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype which affects the host morphology during pathogen invasion. This relates to the pathogen colonization of the body, tissues, or cells of the host organism http://purl.obolibrary.org/obo/PHIPO_0001003 normal formation of extra-invasive hyphal membrane http://purl.obolibrary.org/obo/PHIPO_0001005 normal host morphology during pathogen invasion A pathogen host interaction phenotype where the morphology of the host extra-invasive hyphal membrane (GO:0085039) during pathogen invasion is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001004 normal pathogen morphology during colonization of host http://purl.obolibrary.org/obo/PHIPO_0000998 pathogen morphology phenotype during colonization of host A pathogen host interaction phenotype where the morphology of the pathogen during host colonization is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001005 normal host morphology during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0001002 host morphology phenotype during pathogen invasion A pathogen host interaction phenotype where the morphology of the host during pathogen invasion is normal (indistinguishable from wild type). This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001006 abnormal host morphology during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0001002 host morphology phenotype during pathogen invasion A pathogen host interaction phenotype where the morphology of the host during pathogen invasion is abnormal. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001008 abnormal transport during vegetative growth http://purl.obolibrary.org/obo/PHIPO_0000257 abnormal transport A phenotype in which a specific transport process is abnormal in the vegetative growth phase of the life cycle. http://purl.obolibrary.org/obo/PHIPO_0001009 abnormal vesicle-mediated transport during vegetative growth http://purl.obolibrary.org/obo/PHIPO_0000257 abnormal transport A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001010 normal vesicle-mediated transport during vegetative growth http://purl.obolibrary.org/obo/PHIPO_0001011 normal transport A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001011 normal transport http://purl.obolibrary.org/obo/PHIPO_0000256 transport phenotype A single organism cellular process phenotype observed in the vegetative growth phase of the life cycle in which transport is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001014 increased level of host defense-induced callose deposition http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001015 decreased level of host defense-induced callose deposition http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001017 long germ tube http://purl.obolibrary.org/obo/PHIPO_0000940 abnormal germ tube A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is longer than normal. (GO:0032179) http://purl.obolibrary.org/obo/PHIPO_0001018 abnormal asexual spore germination http://purl.obolibrary.org/obo/PHIPO_0000930 cellular process phenotype A cellular process phenotype in which asexual spore germination is abnormal (GO:0009847). http://purl.obolibrary.org/obo/PHIPO_0001019 decreased rate of asexual spore germination http://purl.obolibrary.org/obo/PHIPO_0001018 abnormal asexual spore germination A cellular process phenotype in which the rate, or speed, of asexual spore germination is decreased. http://purl.obolibrary.org/obo/PHIPO_0001020 sensitive to calcofluor white http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A phenotype in which a population of a single-species shows increased sensitivity to calcofluor white, manifested as an affect on the extent of population growth. (CHEBI:50011) http://purl.obolibrary.org/obo/PHIPO_0001021 sensitive to congo red http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A phenotype in which a population of a single-species shows increased sensitivity to congo red, manifested as an affect on the extent of population growth. (CHEBI:34653). http://purl.obolibrary.org/obo/PHIPO_0001022 altered cellular cAMP level http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell A single species cell phenotype in which the amount of cyclic AMP measured in a cell differs from normal. http://purl.obolibrary.org/obo/PHIPO_0001023 decreased cellular cAMP level http://purl.obolibrary.org/obo/PHIPO_0001035 decreased level of substance in cell A single species cell phenotype in which the amount of cyclic AMP measured in a cell is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001024 increased cellular cAMP level http://purl.obolibrary.org/obo/PHIPO_0001036 increased level of substance in cell A single species cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001025 altered protein level http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell A single species cell phenotype in which the amount of protein measured in a cell differs from normal. Total protein or a specific protein may be affected. http://purl.obolibrary.org/obo/PHIPO_0001026 increased protein level http://purl.obolibrary.org/obo/PHIPO_0001036 increased level of substance in cell A single species cell phenotype in which the amount of protein measured in a cell is higher than normal. Total protein or a specific protein may be affected. http://purl.obolibrary.org/obo/PHIPO_0001027 decreased protein level http://purl.obolibrary.org/obo/PHIPO_0001035 decreased level of substance in cell A single species cell phenotype in which the amount of protein measured in a cell is lower than normal. Total protein or a specific protein may be affected. http://purl.obolibrary.org/obo/PHIPO_0001028 abolished protein localization to plasma membrane http://purl.obolibrary.org/obo/PHIPO_0000245 abolished protein localization A single organism phenotype in which the localization of a protein to the plasma membrane is abolished (GO:0072659). http://purl.obolibrary.org/obo/PHIPO_0001029 abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm http://purl.obolibrary.org/obo/PHIPO_0001028 abolished protein localization to plasma membrane A single organism phenotype in which the localization of a protein to the plasma membrane is abolished, and the protein is present in the cytoplasm instead. http://purl.obolibrary.org/obo/PHIPO_0001030 altered cellular toxin level http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell A single species cell phenotype in which the amount of toxin measured in a cell differs from normal. http://purl.obolibrary.org/obo/PHIPO_0001031 decreased cellular toxin level http://purl.obolibrary.org/obo/PHIPO_0001035 decreased level of substance in cell A single species cell phenotype in which the amount of toxin measured in a cell is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001032 decreased level of pyocyanin http://purl.obolibrary.org/obo/PHIPO_0001031 decreased cellular toxin level A single species cell phenotype in which the amount of pyocyanin measured in a cell is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001033 pyocyanin absent from cell http://purl.obolibrary.org/obo/PHIPO_0001034 substance absent from cell A single species cell phenotype in which the amount of pyocyanin measured in a cell is too low to detect. http://purl.obolibrary.org/obo/PHIPO_0001034 substance absent from cell http://purl.obolibrary.org/obo/PHIPO_0001035 decreased level of substance in cell A single species cell phenotype in which the amount of a specific substance measured in a cell is too low to detect. http://purl.obolibrary.org/obo/PHIPO_0001035 decreased level of substance in cell http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell A single species cell phenotype in which the amount of a specific substance measured in a cell is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001036 increased level of substance in cell http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell A single species cell phenotype in which the amount of a specific substance measured in a cell is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001037 increased cellular toxin level http://purl.obolibrary.org/obo/PHIPO_0001036 increased level of substance in cell A single species cell phenotype in which the amount of toxin measured in a cell is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001038 normal level of substance in cell http://purl.obolibrary.org/obo/PHIPO_0000403 normal cell phenotype A single species cell phenotype in which the amount of a specific substance measured in a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001039 normal cellular toxin level http://purl.obolibrary.org/obo/PHIPO_0001038 normal level of substance in cell A single species cell phenotype in which the amount of toxin measured in a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001043 level of pathogen produced toxin within host phenotype http://purl.obolibrary.org/obo/PHIPO_0001197 level of pathogen produced substance within host phenotype A pathogen host interaction phenotype, which affects the level of pathogen produced toxin during host infection. http://purl.obolibrary.org/obo/PHIPO_0001045 decreased level of pathogen produced toxin within host http://purl.obolibrary.org/obo/PHIPO_0001043 level of pathogen produced toxin within host phenotype A pathogen host interaction phenotype, in which the level of pathogen produced toxin usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001046 increased level of pathogen produced toxin within host http://purl.obolibrary.org/obo/PHIPO_0001043 level of pathogen produced toxin within host phenotype A pathogen host interaction phenotype, in which the level of pathogen produced toxin usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001047 pathogen toxin within host absent http://purl.obolibrary.org/obo/PHIPO_0001045 decreased level of pathogen produced toxin within host A pathogen host interaction phenotype, in which the pathogen produced toxin usually present during infection is absent or at a level too low to detect. http://purl.obolibrary.org/obo/PHIPO_0001049 unicellular colony shape phenotype http://purl.obolibrary.org/obo/PHIPO_0001208 unicellular colony morphology phenotype A single species population phenotype affecting the shape of a colony of unicellular individuals. http://purl.obolibrary.org/obo/PHIPO_0001051 abnormal unicellular colony shape http://purl.obolibrary.org/obo/PHIPO_0001049 unicellular colony shape phenotype A single species phenotype where the shape of a colony of unicellular individuals is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001052 hyper-smooth unicellular colony shape http://purl.obolibrary.org/obo/PHIPO_0001051 abnormal unicellular colony shape A single species colony shape phenotype where the colony is smoother than normal. http://purl.obolibrary.org/obo/PHIPO_0001053 hyper-rugose unicellular colony shape http://purl.obolibrary.org/obo/PHIPO_0001051 abnormal unicellular colony shape A single species phenotype where the shape of a colony of unicellular individuals is more rugose (wrinkled; corrugated) than normal. http://purl.obolibrary.org/obo/PHIPO_0001057 normal unicellular colony shape http://purl.obolibrary.org/obo/PHIPO_0001049 unicellular colony shape phenotype A single species phenotype where the shape of a colony of unicellular individuals is normal (indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001058 normal rugose unicellular colony shape http://purl.obolibrary.org/obo/PHIPO_0001057 normal unicellular colony shape A single species phenotype where the shape of a colony of unicellular individuals is as rugose (wrinkled; corrugated) as normal (indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001059 increased level of pyocyanin http://purl.obolibrary.org/obo/PHIPO_0001037 increased cellular toxin level A single species cell phenotype in which the amount of pyocyanin measured in a cell is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001060 altered RNA level http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell A single species cell phenotype in which the amount of RNA measured in a cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0001061 decreased RNA level http://purl.obolibrary.org/obo/PHIPO_0001060 altered RNA level A singe species cell phenotype in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0001062 increased RNA level http://purl.obolibrary.org/obo/PHIPO_0001060 altered RNA level A single species cell phenotype in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0001063 RNA absent from cell http://purl.obolibrary.org/obo/PHIPO_0001060 altered RNA level A single species cell phenotype in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0001064 normal RNA level http://purl.obolibrary.org/obo/PHIPO_0001038 normal level of substance in cell A single species cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0001068 survival of host organism with pathogen http://purl.obolibrary.org/obo/PHIPO_0001070 host organism viability with pathogen phenotype A host organism viability phenotype where the host organism survives in the presence of the pathogen. http://purl.obolibrary.org/obo/PHIPO_0001069 death of host organism with pathogen http://purl.obolibrary.org/obo/PHIPO_0001070 host organism viability with pathogen phenotype A host organism viability phenotype where the host organism death is accelerated by the pathogen. http://purl.obolibrary.org/obo/PHIPO_0001070 host organism viability with pathogen phenotype http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction organism level phenotype which affects the viability of an individual host organism in the presence of a pathogen. http://purl.obolibrary.org/obo/PHIPO_0001074 sensitive to iron ion starvation http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress A growth phenotype which describes the sensitivity of individuals or populations after exposure to iron ion starvation. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. http://purl.obolibrary.org/obo/PHIPO_0001075 auxotrophic growth http://purl.obolibrary.org/obo/PHIPO_0001216 nutrient phenotype A growth phenotype which describes an individual or a population of organisms which requires a particular organic compound, which is not required by a wild-type for its growth. Auxotrophy usually results from a cell's inability to synthesize the compound. http://purl.obolibrary.org/obo/PHIPO_0001076 growth auxotrophic for lysine http://purl.obolibrary.org/obo/PHIPO_0001075 auxotrophic growth A growth phenotype which describes an individual or a population of organisms which requires lysine for growth. Auxotrophy usually results from a cell's inability to synthesize the compound. http://purl.obolibrary.org/obo/PHIPO_0001077 decreased cellular melanin accumulation http://purl.obolibrary.org/obo/PHIPO_0000288 decreased cellular pigment accumulation A single species individual organism phenotype where the accumulation of melanin in a cell is decreased. http://purl.obolibrary.org/obo/PHIPO_0001078 absence of cellular melanin accumulation http://purl.obolibrary.org/obo/PHIPO_0001077 decreased cellular melanin accumulation A single species individual organism phenotype where the accumulation of melanin in a cell is absent. http://purl.obolibrary.org/obo/PHIPO_0001080 altered pathogen pigment accumulation within host http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype, in which the accumulation of pathogen pigmentation (coloring matter) usually present during infection differs from normal. http://purl.obolibrary.org/obo/PHIPO_0001081 absence of melanin accumulation in pathogen asexual spore within host http://purl.obolibrary.org/obo/PHIPO_0001080 altered pathogen pigment accumulation within host A pathogen host interaction, in which the accumulation of melanin within a pathogen asexual spore, usually present during infection, is absent. http://purl.obolibrary.org/obo/PHIPO_0001083 host defense-induced callose deposition present http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, in which the level of host produced callose deposition usually present during infection is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001084 increased unicellular population growth rate http://purl.obolibrary.org/obo/PHIPO_0000975 increased unicellular population growth A single species population growth phenotype where the rate of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is faster than normal. http://purl.obolibrary.org/obo/PHIPO_0001085 decreased unicellular population growth rate http://purl.obolibrary.org/obo/PHIPO_0000974 decreased unicellular population growth A single species population growth phenotype where the rate of the increase in the number of unicellular organisms in the population (i.e organismal growth and reproduction) is slower than normal. http://purl.obolibrary.org/obo/PHIPO_0001086 abnormal cellular component assembly http://purl.obolibrary.org/obo/PHIPO_0000400 abnormal cellular component organization A single species cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001088 decreased rate of hyphae formation http://purl.obolibrary.org/obo/PHIPO_0001212 decreased hyphal growth An individual organism growth phenotype in which the rate, or speed, of hyphae formation is decreased. http://purl.obolibrary.org/obo/PHIPO_0001089 decreased rate of germination tube formation http://purl.obolibrary.org/obo/PHIPO_0001212 decreased hyphal growth An individual organism growth phenotype in which the rate, or speed, of germ tube formation is decreased resulting in decreased hyphal growth. http://purl.obolibrary.org/obo/PHIPO_0001090 abolished protein secretion http://purl.obolibrary.org/obo/PHIPO_0000245 abolished protein localization A single organism localization phenotype in which a protein is not exported via the secretory pathway. http://purl.obolibrary.org/obo/PHIPO_0001091 abolished chitinase activity http://purl.obolibrary.org/obo/PHIPO_0000435 abolished catalytic activity A single species molecular function phenotype in which a chitinase activity is absent. http://purl.obolibrary.org/obo/PHIPO_0001092 increased chitin level in asexual spore http://purl.obolibrary.org/obo/PHIPO_0001094 abnormal localization A single species cell phenotype in which the amount of chitin measured in the spore is higher than normal http://purl.obolibrary.org/obo/PHIPO_0001094 abnormal localization http://purl.obolibrary.org/obo/PHIPO_0000235 localization phenotype A single species phenotype where the localization of a structure or substance in a cell is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001095 abnormal localization of chitin in cell http://purl.obolibrary.org/obo/PHIPO_0001094 abnormal localization A single organism phenotype in which the localization of chitin in a cell is abnormal. Chitin may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. http://purl.obolibrary.org/obo/CL_0011026 progenitor cell http://purl.obolibrary.org/obo/CL_0011115 precursor cell A precursor cell that has a tendency to differentiate into a specific type of cell. They are descendants of stem cells, only they are more constrained in their differentiation potential or capacity for self-renewal, and are often more limited in both senses. http://purl.obolibrary.org/obo/CL_0019018 blood vessel smooth muscle cell http://purl.obolibrary.org/obo/CL_0000359 vascular associated smooth muscle cell A smooth muscle cell that is part of any blood vessel. http://purl.obolibrary.org/obo/CL_0019019 tracheobronchial smooth muscle cell http://purl.obolibrary.org/obo/CL_0000192 smooth muscle cell A smooth muscle cell that is part of the tracheobronchial tree. http://purl.obolibrary.org/obo/PHIPO_0001226 decreased level of host defense-induced reducing sugar in apoplast http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, in which the level of host produced reducing sugars usually present in the apoplast during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001227 increased level of host defense-induced reducing sugar in apoplast http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, in which the level of host produced reducing sugars usually present in the apoplast during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001228 pathogen reactive oxygen species production within host present http://purl.obolibrary.org/obo/PHIPO_0001197 level of pathogen produced substance within host phenotype A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is present as normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001229 presence of pathogen tissue to tissue migration within host http://purl.obolibrary.org/obo/PHIPO_0001159 pathogen tissue to tissue migration within host phenotype A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is present. http://purl.obolibrary.org/obo/PHIPO_0001230 host defense-induced phenolic compound present http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, in which the host phenolic compounds usually present during infection are normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/UBERON_8000009 Purkinje fiber network http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle A collection of Purkinje fibers that receives signals from the right and left bundle branches and innervates the ventricular cardiac muscle. The Purkinje fiber network creates synchronized contractions of the heart ventricles. http://purl.obolibrary.org/obo/CHEBI_167559 glycan http://purl.obolibrary.org/obo/CHEBI_78616 carbohydrates and carbohydrate derivatives Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001. http://purl.obolibrary.org/obo/PATO_0070002 basket cell morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in multipolar neurons with densely branched terminal axonal arborizations that form basket-like structures surrounding and synapsing to the somas of target cells. http://purl.obolibrary.org/obo/PATO_0070025 unipolar neuron morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons with only one process, a neurite, that extends from the cell body. The neurite then branches to form dendritic and axonal processes. http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology http://purl.obolibrary.org/obo/PATO_0010006 cell morphology A cell morphology that inheres in neurons which possess three or more neurites, usually a single axon and many dendrites and dendritic branches. http://purl.obolibrary.org/obo/PHIPO_0001235 host defense-related RNA involved in a pathogen interaction present http://purl.obolibrary.org/obo/PHIPO_0001231 host defense-induced RNA present A pathogen host interaction phenotype, in which the host defense-related RNA usually present during infection is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001236 effector-mediated suppression of host effector triggered immunity absent http://purl.obolibrary.org/obo/PHIPO_0001176 effector-mediated immune suppression phenotype A phenotype where the process of host tissue cell death causing a host lesion initially induced by the host activating its own hypersensitive response in defense, is subsequently not suppressed by a pathogen effector. http://purl.obolibrary.org/obo/PHIPO_0001237 effector-mediated suppression of host PAMP-triggered immunity absent http://purl.obolibrary.org/obo/PHIPO_0001176 effector-mediated immune suppression phenotype A cell signaling pathway phenotype where the molecular pattern-induced host innate immune response signaling pathway is not suppressed by a pathogen. (GO:0052034) http://purl.obolibrary.org/obo/PHIPO_0001238 increased chitinase activity http://purl.obolibrary.org/obo/PHIPO_0000437 increased catalytic activity A single species molecular function phenotype in which the observed rate of chitinase activity is increased. http://purl.obolibrary.org/obo/PHIPO_0001239 pathogen inhibition of host defense induced alkalization http://purl.obolibrary.org/obo/PHIPO_0001108 pathogen host interaction pH phenotype A pathogen host interaction phenotype where the host induced pH increase in response to pathogen colonization is inhibited. http://purl.obolibrary.org/obo/PHIPO_0001240 host defense induced alkalization present http://purl.obolibrary.org/obo/PHIPO_0001108 pathogen host interaction pH phenotype A pathogen host interaction phenotype where the host induces a pH increase in response to pathogen colonization. http://purl.obolibrary.org/obo/PHIPO_0001241 decreased chitinase activity http://purl.obolibrary.org/obo/PHIPO_0000436 decreased catalytic activity A single species molecular function phenotype in which the observed rate of chitinase activity is decreased. http://purl.obolibrary.org/obo/PHIPO_0001242 pathogen binding of chitin with host present http://purl.obolibrary.org/obo/PHIPO_0000164 pathogen host interaction binding phenotype A molecular function phenotype in which the binding of chitin or chitin fragments by the pathogen during host colonization is present. http://purl.obolibrary.org/obo/PHIPO_0001243 pathogen binding of chitin with host absent http://purl.obolibrary.org/obo/PHIPO_0000164 pathogen host interaction binding phenotype A molecular function phenotype in which the binding of chitin or chitin fragments by the pathogen during host colonization is absent. http://purl.obolibrary.org/obo/PHIPO_0001244 increased number of pathogen asexual sporulation structures within host lesion http://purl.obolibrary.org/obo/PHIPO_0000469 abnormal pathogen asexual sporulation within host A pathogen reproductive phenotype within host in which the frequency of occurrence of asexual sporulation structures within a host lesion is greater than normal. http://purl.obolibrary.org/obo/PHIPO_0001245 increased protein phosphorylation involved in host PAMP-triggered immunity (MAPK) signaling activated by pathogen http://purl.obolibrary.org/obo/PHIPO_0001140 host PAMP-triggered immunity signaling activated by pathogen present A host immune system signaling pathway pathogen-host interaction phenotype observed during the activation of host PAMP-triggered immunity in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal. http://purl.obolibrary.org/obo/PHIPO_0001246 host PAMP-triggered immunity activated by pathogen present http://purl.obolibrary.org/obo/PHIPO_0001167 pathogen modulation of host immune system process phenotype A phenotype where the process of pathogen-associated molecular pattern (PAMPs) or microbe-associated molecular pattern (MAMPs), activate the host PAMP-triggered immunity (PTI) innate immune system to trigger host defense responses such as reactive oxygen species (ROS) and callose deposition is present. (PAMPs and MAMPs are conserved structures among microbial species, eg chitin and lipopolysaccharide (LPS)). http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype http://purl.obolibrary.org/obo/PHIPO_0001173 pathogen modulation of host process phenotype A pathogen host interaction phenotype, in which a pathogen effects a change in the metabolic processes of its host organism. http://purl.obolibrary.org/obo/PHIPO_0001248 pathogen modulation of chitin hydrolysis by host present http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype, in which a pathogen effector preventing the hydrolysis of chitin by host chitinases is present. http://purl.obolibrary.org/obo/PHIPO_0001249 chitin hydrolysis absent http://purl.obolibrary.org/obo/PHIPO_0001147 cellular metabolic process phenotype A single species metabolic cellular process phenotype, in which a pathogen effector prevents the hydrolysis of chitin by chitinases. http://purl.obolibrary.org/obo/CL_4023154 myelinating glial cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A glial cell that myelinates axonal processes. http://purl.obolibrary.org/obo/CL_4307030 Astro-NT NN_1 Nuf2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Sfrp5 (Mmus), Cldn10 (Mmus), Riiad1 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Nuf2, Shroom3. These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5210 Astro-NT NN_1. http://purl.obolibrary.org/obo/CHEBI_747204 reference compound http://purl.obolibrary.org/obo/CHEBI_51086 chemical role Any well-characterized compound that serves as a standard for the identification, quantification, calibration, or quality control of substances in scientific analysis. http://purl.obolibrary.org/obo/CHEBI_10545 electron http://purl.obolibrary.org/obo/CHEBI_36338 lepton Elementary particle not affected by the strong force having a spin ½, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV. http://purl.obolibrary.org/obo/CHEBI_15734 primary alcohol http://purl.obolibrary.org/obo/CHEBI_30879 alcohol A primary alcohol is a compound in which a hydroxy group, ‒OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. http://purl.obolibrary.org/obo/CHEBI_17478 aldehyde http://purl.obolibrary.org/obo/CHEBI_36586 carbonyl compound A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group. http://purl.obolibrary.org/obo/CHEBI_23643 depsipeptide http://purl.obolibrary.org/obo/CHEBI_16670 peptide A natural or synthetic compound having a sequence of amino and hydroxy carboxylic acid residues (usually α-amino and α-hydroxy acids), commonly but not necessarily regularly alternating. http://purl.obolibrary.org/obo/CHEBI_24127 fungicide http://purl.obolibrary.org/obo/CHEBI_35718 antifungal agent A substance used to destroy fungal pests. http://purl.obolibrary.org/obo/CHEBI_24400 glycoside http://purl.obolibrary.org/obo/CHEBI_63161 glycosyl compound A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO‒, RS‒, RSe‒, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively. http://purl.obolibrary.org/obo/CHEBI_24436 guanidines http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R1R2N)(R3R4N)C=N-R5 and are related structurally to amidines and ureas. http://purl.obolibrary.org/obo/CHEBI_24848 inositol http://purl.obolibrary.org/obo/CHEBI_23451 cyclitol Any cyclohexane-1,2,3,4,5,6-hexol. http://purl.obolibrary.org/obo/CHEBI_25481 naphthoquinone http://purl.obolibrary.org/obo/CHEBI_36141 quinone A polycyclic aromatic ketone metabolite of naphthalene. http://purl.obolibrary.org/obo/CHEBI_25754 oxo carboxylic acid http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid Any compound that has an aldehydic or ketonic group as well as a carboxylic acid group in the same molecule. http://purl.obolibrary.org/obo/CHEBI_2682 amphotericin B http://purl.obolibrary.org/obo/CHEBI_25105 macrolide antibiotic A macrolide antibiotic used to treat potentially life-threatening fungal infections. http://purl.obolibrary.org/obo/CHEBI_32863 secondary amine http://purl.obolibrary.org/obo/CHEBI_50995 secondary amino compound A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/CHEBI_33286 agrochemical http://purl.obolibrary.org/obo/CHEBI_33232 application An agrochemical is a substance that is used in agriculture or horticulture. http://purl.obolibrary.org/obo/CHEBI_35625 EC 3.5.2.6 (beta-lactamase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76808 EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of β-lactamase (EC 3.5.2.6). http://purl.obolibrary.org/obo/CHEBI_35790 oxazole http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom. http://purl.obolibrary.org/obo/CHEBI_36338 lepton http://purl.obolibrary.org/obo/CHEBI_36340 fermion Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek λεπτοσ (small, thin). http://purl.obolibrary.org/obo/CHEBI_37912 hydroxycoumarin http://purl.obolibrary.org/obo/CHEBI_23403 coumarins Any coumarin carrying at least one hydroxy substituent. http://purl.obolibrary.org/obo/CHEBI_38337 pyrimidone http://purl.obolibrary.org/obo/CHEBI_39447 pyrimidines A pyrimidine carrying one or more oxo substituents. http://purl.obolibrary.org/obo/CHEBI_38532 hydrazone http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Compounds having the structure R2C=NNR2, formally derived from aldehydes or ketones by replacing =O by =NNH2 (or substituted analogues). http://purl.obolibrary.org/obo/CHEBI_50492 thiocarbonyl compound http://purl.obolibrary.org/obo/CHEBI_33261 organosulfur compound Any compound containing the thiocarbonyl group, C=S. http://purl.obolibrary.org/obo/CHEBI_73539 naphthyridine derivative http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound Any organonitrogen heterocyclic compound that is a derivative of a naphthyridine. http://purl.obolibrary.org/obo/CHEBI_77746 human metabolite http://purl.obolibrary.org/obo/CHEBI_75768 mammalian metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes http://purl.obolibrary.org/obo/CHEBI_23132 chlorobenzenes Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine. http://purl.obolibrary.org/obo/CHEBI_16385 organic sulfide http://purl.obolibrary.org/obo/CHEBI_26822 sulfide Compounds having the structure RSR (R ≠ H). Such compounds were once called thioethers. http://purl.obolibrary.org/obo/CHEBI_17489 3',5'-cyclic AMP http://purl.obolibrary.org/obo/CHEBI_61296 adenyl ribonucleotide A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. http://purl.obolibrary.org/obo/CHEBI_27881 resveratrol http://purl.obolibrary.org/obo/CHEBI_36027 stilbenol A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_28866 tetracosanoic acid http://purl.obolibrary.org/obo/CHEBI_39418 straight-chain saturated fatty acid A C24 straight-chain saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_51454 cyclopropanes http://purl.obolibrary.org/obo/CHEBI_33598 carbocyclic compound Cyclopropane and its derivatives formed by substitution. http://purl.obolibrary.org/obo/CHEBI_58955 branched-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion with a carbon side-chain or isopropyl termination. http://purl.obolibrary.org/obo/CHEBI_59836 oxo fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion A fatty acid anion carrying one or more oxo substituents http://purl.obolibrary.org/obo/CHEBI_84186 L-proline derivative http://purl.obolibrary.org/obo/CHEBI_26273 proline derivative A proteinogenic amino acid derivative resulting from reaction of L-proline at the amino group or the carboxy group, or from the replacement of any hydrogen of L-proline by a heteroatom. http://purl.obolibrary.org/obo/CHEBI_130181 calmodulin antagonist http://purl.obolibrary.org/obo/CHEBI_48706 antagonist An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin. http://purl.obolibrary.org/obo/CHEBI_16313 D-proline http://purl.obolibrary.org/obo/CHEBI_26271 proline The D-enantiomer of proline. http://purl.obolibrary.org/obo/CHEBI_17608 D-aldohexose http://purl.obolibrary.org/obo/CHEBI_4194 D-hexose Any D-aldose having a chain of six carbon atoms in the molecule. http://purl.obolibrary.org/obo/CHEBI_17634 D-glucose http://purl.obolibrary.org/obo/CHEBI_17608 D-aldohexose A glucose with D-configuration. http://purl.obolibrary.org/obo/CHEBI_18254 ribonucleoside http://purl.obolibrary.org/obo/CHEBI_47019 dihydroxytetrahydrofuran Any nucleoside where the sugar component is D-ribose. http://purl.obolibrary.org/obo/CHEBI_26208 polyunsaturated fatty acid http://purl.obolibrary.org/obo/CHEBI_27208 unsaturated fatty acid Any fatty acid containing more than one double bond. Acids in this group are reported to have cardioprotective effects; and levels are lowered in chronic fatigue syndrome. http://purl.obolibrary.org/obo/CHEBI_37142 organoiodine compound http://purl.obolibrary.org/obo/CHEBI_17792 organohalogen compound An organoiodine compound is a compound containing at least one carbon-iodine bond. http://purl.obolibrary.org/obo/CHEBI_48706 antagonist http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. http://purl.obolibrary.org/obo/CHEBI_26836 sulfuric acid http://purl.obolibrary.org/obo/CHEBI_33402 sulfur oxoacid A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom. http://purl.obolibrary.org/obo/CHEBI_26959 thiocarboxylic ester http://purl.obolibrary.org/obo/CHEBI_35701 ester An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur. http://purl.obolibrary.org/obo/CHEBI_27081 transition element atom http://purl.obolibrary.org/obo/CHEBI_33521 metal atom An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell. http://purl.obolibrary.org/obo/CHEBI_28001 vancomycin http://purl.obolibrary.org/obo/CHEBI_24396 glycopeptide A complex glycopeptide from Streptomyces orientalis. It inhibits a specific step in the synthesis of the peptidoglycan layer in the Gram-positive bacteria Staphylococcus aureus and Clostridium difficile. http://purl.obolibrary.org/obo/CHEBI_28545 valinomycin http://purl.obolibrary.org/obo/CHEBI_35213 cyclodepsipeptide A twelve-membered cyclodepsipeptide composed of three repeating D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains. http://purl.obolibrary.org/obo/CHEBI_33672 heterobicyclic compound http://purl.obolibrary.org/obo/CHEBI_33636 bicyclic compound A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom. http://purl.obolibrary.org/obo/CHEBI_35186 terpene http://purl.obolibrary.org/obo/CHEBI_24632 hydrocarbon A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]. http://purl.obolibrary.org/obo/CHEBI_35816 leprostatic drug http://purl.obolibrary.org/obo/CHEBI_64912 antimycobacterial drug A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions. http://purl.obolibrary.org/obo/CHEBI_35842 antirheumatic drug http://purl.obolibrary.org/obo/CHEBI_23888 drug A drug used to treat rheumatoid arthritis. http://purl.obolibrary.org/obo/CHEBI_35862 bacitracin A http://purl.obolibrary.org/obo/CHEBI_24613 homodetic cyclic peptide A homodetic cyclic peptide consisting of (4R)-2-[(1S,2S)-1-amino-2-methylbutyl]-4,5-dihydro-1,3-thiazole-4-carboxylic acid attached head-to-tail to L-leucyl,D-glutamyl, L-lysyl, D-ornityl, L-isoleucyl, D-phenylalanyl, L-histidyl. D-aspartyl and L-asparaginyl residues coupled in sequence and cyclised by condensation of the side-chain amino group of the L-lysyl residue with the C-terminal carboxylic acid group. It is the major component of bacitracin. http://purl.obolibrary.org/obo/CHEBI_37416 EC 2.7.7.6 (RNA polymerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76815 EC 2.7.7.* (nucleotidyltransferase) inhibitor An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the action of RNA polymerase (EC 2.7.7.6). http://purl.obolibrary.org/obo/CHEBI_38186 isonicotinate http://purl.obolibrary.org/obo/CHEBI_38181 pyridinemonocarboxylate A pyridinemonocarboxylate resulting from the deprotonation of the carboxy group of isonicotinic acid. http://purl.obolibrary.org/obo/CHEBI_39442 fluorescent probe http://purl.obolibrary.org/obo/CHEBI_50406 probe A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy. http://purl.obolibrary.org/obo/CHEBI_40009 D-cycloserine http://purl.obolibrary.org/obo/CHEBI_25807 organooxygen heterocyclic antibiotic A 4-amino-1,2-oxazolidin-3-one that has R configuration. It is an antibiotic produced by Streptomyces garyphalus or S. orchidaceus and is used as part of a multi-drug regimen for the treatment of tuberculosis when resistance to, or toxicity from, primary drugs has developed. An analogue of D-alanine, it interferes with bacterial cell wall synthesis in the cytoplasm by competitive inhibition of L-alanine racemase (which forms D-alanine from L-alanine) and D-alanine—D-alanine ligase (which incorporates D-alanine into the pentapeptide required for peptidoglycan formation and bacterial cell wall synthesis). http://purl.obolibrary.org/obo/CHEBI_47724 vancomycin aglycone http://purl.obolibrary.org/obo/CHEBI_26195 polyphenol A peptide antibiotic that is vancomycin lacking the disaccharide moiety. http://purl.obolibrary.org/obo/CHEBI_48923 erythromycin http://purl.obolibrary.org/obo/CHEBI_23953 erythromycins Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus). http://purl.obolibrary.org/obo/CHEBI_50635 EC 3.5.1.5 (urease) inhibitor http://purl.obolibrary.org/obo/CHEBI_76807 EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the activity of urease (EC 3.5.1.5), reducing hydrolysis. http://purl.obolibrary.org/obo/CHEBI_51151 dipolar compound http://purl.obolibrary.org/obo/CHEBI_72695 organic molecule An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case. http://purl.obolibrary.org/obo/CHEBI_58549 kanamycin B(5+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation that is the pentacation of kanamycin B, obtained by protonation of the primary amino groups. http://purl.obolibrary.org/obo/CHEBI_58950 very long-chain fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion Any fatty acid anion with a chain length greater than C22. http://purl.obolibrary.org/obo/CHEBI_64047 food additive http://purl.obolibrary.org/obo/CHEBI_78295 food component Any substance which is added to food to preserve or enhance its flavour and/or appearance. http://purl.obolibrary.org/obo/CHEBI_64933 melanin synthesis inhibitor http://purl.obolibrary.org/obo/CHEBI_59864 depigmentation drug A depigmentation agent which inhibits the synthesis of melanin. http://purl.obolibrary.org/obo/CHEBI_64946 anti-HIV agent http://purl.obolibrary.org/obo/CHEBI_22587 antiviral agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. http://purl.obolibrary.org/obo/CHEBI_71339 novobiocin(1-) http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the conjugate base of novobiocin. http://purl.obolibrary.org/obo/CHEBI_71365 rifampicin zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion A zwitterion obtained by transfer of a proton from the 5-hydroxy group to the tertiary amino group of rifampicin; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_71392 tetracycline(1-) http://purl.obolibrary.org/obo/CHEBI_25696 organic anion An organic anion that is the conjugate base of tetracycline zwitterion obtained by deprotonation of the two enolic hydroxy groups and protonation of the tertiary amino group. http://purl.obolibrary.org/obo/CHEBI_72600 spiroketal http://purl.obolibrary.org/obo/CHEBI_37948 oxaspiro compound A cyclic ketal in which the ketal carbon is the only common atom of two rings. http://purl.obolibrary.org/obo/CHEBI_75592 L-cycloserine http://purl.obolibrary.org/obo/CHEBI_23503 4-amino-1,2-oxazolidin-3-one A 4-amino-1,2-oxazolidin-3-one that has S configuration. An antibiotic isolated from Erwinia uredovora. http://purl.obolibrary.org/obo/CHEBI_75616 gentamicin C(5+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the five amino groups of any gentamicin C. http://purl.obolibrary.org/obo/CHEBI_76842 vancomycin(1+) http://purl.obolibrary.org/obo/CHEBI_25697 organic cation An organic cation that is the conjugate acid of vancomycin, obtained by deprotonation of the carboxy group and protonation of the two amino functions; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_77932 tetracycline zwitterion http://purl.obolibrary.org/obo/CHEBI_144644 a tetracycline zwitterion A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of tetracycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). http://purl.obolibrary.org/obo/CHEBI_83146 Daphnia tenebrosa metabolite http://purl.obolibrary.org/obo/CHEBI_83057 Daphnia metabolite A Daphnia metabolite produced by the species Daphnia tenebrosa. http://purl.obolibrary.org/obo/CHEBI_88184 metal allergen http://purl.obolibrary.org/obo/CHEBI_33521 metal atom Any metal which causes the onset of an allergic reaction. http://purl.obolibrary.org/obo/CHEBI_34608 captan http://purl.obolibrary.org/obo/CHEBI_87198 phthalimide fungicide A dicarboximide that is 3a,4,7,7a-tetrahydrophthalimide in which the hydrogen attached to the nitrogen is replaced by a trichloromethyl group. A non-systemic fungicide introduced in the 1950s, it is widely used for the control of fungal diseases in fruits, vegetables, and ornamental crops. http://purl.obolibrary.org/obo/CHEBI_34653 Congo Red http://purl.obolibrary.org/obo/CHEBI_48960 bis(azo) compound An indicator dye that is blue-violet at pH 3.0 and red at pH 5.0. http://purl.obolibrary.org/obo/CHEBI_3478 cefaclor http://purl.obolibrary.org/obo/CHEBI_23066 cephalosporin A cephalosporin bearing chloro and (R)-2-amino-2-phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. http://purl.obolibrary.org/obo/CHEBI_3499 cefotetan http://purl.obolibrary.org/obo/CHEBI_55429 cephamycin A semi-synthetic second-generation cephamycin antibiotic with [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl, methoxy and {[4-(2-amino-1-carboxy-2-oxoethylidene)-1,3-dithietan-2-yl]carbonyl}amino groups at the 3, 7α, and 7β positions, respectively, of the cephem skeleton. It is resistant to a wide range of β-lactamases and is active against a broad spectrum of aerobic and anaerobic Gram-positive and Gram-negative microorganisms. http://purl.obolibrary.org/obo/CHEBI_34994 teicoplanin A2 http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes Any of the glycopeptides whose structure consists of teicoplanin A3-1 in which the hydroxy group of the di(aryloxy)-substituted phenol moiety has been converted to the corresponding 2-acylamino-2-deoxy-β-D-glucoside. Members of the class differ only in the nature of the acyl group. http://purl.obolibrary.org/obo/CHEBI_35014 thiophanate-methyl http://purl.obolibrary.org/obo/CHEBI_87061 carbamate fungicide A member of the class of thioureas that is the dimethyl ester of (1,2-phenylenedicarbamothioyl)biscarbamic acid. A fungicide effective against a broad spectrum of diseases in fruit, vegetables, turf and other crops including eyespot, scab, powdery mildew and grey mould. http://purl.obolibrary.org/obo/CHEBI_3504 cefpodoxime http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis. http://purl.obolibrary.org/obo/CHEBI_3505 cefpodoxime proxetil http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid The 1-[(isopropoxycarbonyl)oxy]ethyl (proxetil) ester prodrug of cefpodoxime. After swallowing, hydrolysis of the ester group occurs in the intestinal epithelium, to release active cefpodoxime in the bloodstream. It is used to treat acute otitis media, pharyngitis, and sinusitis. http://purl.obolibrary.org/obo/CHEBI_3508 ceftazidime http://purl.obolibrary.org/obo/CHEBI_36816 oxime O-ether A third-generation cephalosporin antibiotic bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. http://purl.obolibrary.org/obo/CHEBI_3515 cefuroxime http://purl.obolibrary.org/obo/CHEBI_28084 3-(carbamoyloxymethyl)cephalosporin A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain. http://purl.obolibrary.org/obo/CHEBI_35276 ammonium compound http://purl.obolibrary.org/obo/CHEBI_51143 nitrogen molecular entity Compounds (NH4+)Y− and derivatives, in which one or more of the hydrogens bonded to nitrogen have been replaced with univalent groups. http://purl.obolibrary.org/obo/CHEBI_35281 onium betaine http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom. http://purl.obolibrary.org/obo/CHEBI_3534 cephalexin http://purl.obolibrary.org/obo/CHEBI_72588 semisynthetic derivative A semisynthetic first-generation cephalosporin antibiotic having methyl and β-(2R)-2-amino-2-phenylacetamido groups at the 3- and 7- of the cephem skeleton, respectively. It is effective against both Gram-negative and Gram-positive organisms, and is used for treatment of infections of the skin, respiratory tract and urinary tract. http://purl.obolibrary.org/obo/CHEBI_35496 fluorobenzenes http://purl.obolibrary.org/obo/CHEBI_37143 organofluorine compound Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group. http://purl.obolibrary.org/obo/CHEBI_35568 mancude ring http://purl.obolibrary.org/obo/CHEBI_23367 molecular entity Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds. http://purl.obolibrary.org/obo/CHEBI_35720 enrofloxacin http://purl.obolibrary.org/obo/CHEBI_51454 cyclopropanes A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid substituted by an oxo group at position 4, a fluoro group at position 6, a cyclopropyl group at position 1 and a 4-ethylpiperazin-1-yl group at position 7. It is a veterinary antibacterial agent used for the treatment of pets. http://purl.obolibrary.org/obo/CHEBI_36340 fermion http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi. http://purl.obolibrary.org/obo/CHEBI_36343 composite particle http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A subatomic particle known to have substructure (i.e. consisting of smaller particles). http://purl.obolibrary.org/obo/CHEBI_36344 hadron http://purl.obolibrary.org/obo/CHEBI_36343 composite particle Hadron is a subatomic particle which experiences the strong force. http://purl.obolibrary.org/obo/CHEBI_3639 chlorothalonil http://purl.obolibrary.org/obo/CHEBI_87034 aromatic fungicide A dinitrile that is benzene-1,3-dicarbonitrile substituted by four chloro groups. A non-systemic fungicide first introduced in the 1960s, it is used to control a range of diseases in a wide variety of crops. http://purl.obolibrary.org/obo/CHEBI_36622 benzimidazole http://purl.obolibrary.org/obo/CHEBI_35570 mancude organic heterobicyclic parent A mancude organic heterobicyclic parent that is a heterocyclic organic compound comprising fused benzene and imidazole rings. http://purl.obolibrary.org/obo/CHEBI_36624 naphthyridine http://purl.obolibrary.org/obo/CHEBI_52362 ortho-fused heteroarene Any one of eight organic heterobicyclic compounds that have a naphthalene skeleton in which two of the carbons are replaced by nitrogens. A 'closed' class. http://purl.obolibrary.org/obo/CHEBI_36628 1,8-naphthyridine http://purl.obolibrary.org/obo/CHEBI_36624 naphthyridine A naphthyridine in which the nitrogens are situated at positions 1 and 8. http://purl.obolibrary.org/obo/CHEBI_36756 farnesane http://purl.obolibrary.org/obo/CHEBI_35189 sesquiterpene A sesquiterpene that is dodecane substituted by methyl groups at positions 2, 6 and 10. http://purl.obolibrary.org/obo/CHEBI_3749 clofazimine http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes 3-Isopropylimino-3,5-dihydro-phenazine in which the hydrogen at position 5 is substituted substituted by a 4-chlorophenyl group, and that at position 2 is substituted by a (4-chlorophenyl)amino group. A dark red crystalline solid, clofazimine is an antimycobacterial and is one of the main drugs used for the treatment of multi-bacillary leprosy. However, it can cause red/brown discolouration of the skin, so other treatments are often preferred in light-skinned patients. http://purl.obolibrary.org/obo/CHEBI_37943 colistin http://purl.obolibrary.org/obo/CHEBI_59062 polymyxin A multi-component mixture comprising mostly of colistin A (R = Me) and B (R = H), with small amounts of colistin C and other polymyxins, produced by certain strains of Bacillus polymyxa var. colistinus. An antibiotic, it is used as its sulfate salt (for oral or topical use) or as the sodium salt of the N-methylsulfonic acid derivative (the injectable form) in the treatment of severe Gram-negative infections, partiularly those due to Pseudomonas aeruginosa. http://purl.obolibrary.org/obo/CHEBI_38584 1,3-difluorobenzene http://purl.obolibrary.org/obo/CHEBI_38582 difluorobenzene A difluorobenzene carrying fluoro groups at positions 1 and 3. http://purl.obolibrary.org/obo/CHEBI_45924 trimethoprim http://purl.obolibrary.org/obo/CHEBI_51683 methoxybenzenes An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge. http://purl.obolibrary.org/obo/CHEBI_472657 cefixime http://purl.obolibrary.org/obo/CHEBI_23066 cephalosporin A third-generation cephalosporin antibiotic bearing vinyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(carboxymethoxy)imino]acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is used in the treatment of gonorrhoea, tonsilitis, pharyngitis, bronchitis, and urinary tract infections. http://purl.obolibrary.org/obo/CHEBI_474053 cefazolin http://purl.obolibrary.org/obo/CHEBI_38099 thiadiazoles A first-generation cephalosporin compound having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups at positions 3 and 7 respectively. http://purl.obolibrary.org/obo/CHEBI_478164 cefepime http://purl.obolibrary.org/obo/CHEBI_36816 oxime O-ether A cephalosporin bearing (1-methylpyrrolidinium-1-yl)methyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido groups at positions 3 and 7, respectively, of the cephem skeleton. http://purl.obolibrary.org/obo/CHEBI_48343 disulfide http://purl.obolibrary.org/obo/CHEBI_26835 sulfur molecular entity Compounds of structure RSSR'. http://purl.obolibrary.org/obo/CHEBI_51269 acenes http://purl.obolibrary.org/obo/CHEBI_33836 benzenoid aromatic compound Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives. http://purl.obolibrary.org/obo/CHEBI_52210 pharmacological role http://purl.obolibrary.org/obo/CHEBI_24432 biological role A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. http://purl.obolibrary.org/obo/CHEBI_53657 cefazolin(1-) http://purl.obolibrary.org/obo/CHEBI_52440 cephalosporin carboxylic acid anion A cephalosporin carboxylic acid anion having [(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl and (1H-tetrazol-1-ylacetyl)amino side-groups, formed by proton loss from the carboxy group of cefazolin. http://purl.obolibrary.org/obo/CHEBI_53676 ceftazidime(1-) http://purl.obolibrary.org/obo/CHEBI_52440 cephalosporin carboxylic acid anion A cephalosporin carboxylic acid anion formed by proton loss from the carboxy group of ceftazidime, a cephalosporin having 7β-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino and 3-pyridinium-1-ylmethyl side-groups. http://purl.obolibrary.org/obo/CHEBI_59062 polymyxin http://purl.obolibrary.org/obo/CHEBI_46895 lipopeptide Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria. http://purl.obolibrary.org/obo/CHEBI_59358 cefotetan(2-) http://purl.obolibrary.org/obo/CHEBI_28965 dicarboxylic acid dianion The dianion formed by removal of a proton from each of the carboxylic acid groups of cefotetan. http://purl.obolibrary.org/obo/CHEBI_59392 cephalexin(1-) http://purl.obolibrary.org/obo/CHEBI_52440 cephalosporin carboxylic acid anion The anion resulting from the removal of a proton from the carboxylic acid group of cephalexin. http://purl.obolibrary.org/obo/CHEBI_63046 emulsifier http://purl.obolibrary.org/obo/CHEBI_51086 chemical role The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability. http://purl.obolibrary.org/obo/CHEBI_76775 EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76760 EC 3.1.* (ester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*). http://purl.obolibrary.org/obo/CHEBI_76808 EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide cyclic amide C-N hydrolase (EC 3.5.2.*). http://purl.obolibrary.org/obo/CHEBI_87037 benzimidazole precursor fungicide http://purl.obolibrary.org/obo/CHEBI_35352 organonitrogen compound Compounds based on 1,2-phenylenediamine in which one or both of the primary amino groups have been derivatised so as to permit subsequent benzimidazole formation, and which have been used as fungicides. http://purl.obolibrary.org/obo/CHEBI_87061 carbamate fungicide http://purl.obolibrary.org/obo/CHEBI_23003 carbamate ester Compounds that contain a carbamate ester moiety as a key feature of their structure and which have been used as fungicides. http://purl.obolibrary.org/obo/CHEBI_87198 phthalimide fungicide http://purl.obolibrary.org/obo/CHEBI_87195 dicarboximide fungicide A dicarboximide fungicide whose structure contains a phthalimide derivative. http://purl.obolibrary.org/obo/CHEBI_53628 2,6-dideoxy-alpha-D-glucoside http://purl.obolibrary.org/obo/CHEBI_22390 alpha-D-glucoside An α-D-glucoside deoxygenated at C-2 and C-6. http://purl.obolibrary.org/obo/CHEBI_53634 neomycin C http://purl.obolibrary.org/obo/CHEBI_47779 aminoglycoside A tetracyclic antibacterial agent derived from neomycin, being a glycoside ester of neamine and neobiosamine C. http://purl.obolibrary.org/obo/CHEBI_53661 alexidine http://purl.obolibrary.org/obo/CHEBI_53662 biguanides An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge. http://purl.obolibrary.org/obo/CHEBI_53665 oxazinoquinoline http://purl.obolibrary.org/obo/CHEBI_26979 organic heterotricyclic compound Any organic heterotricyclic compound based on a skeleton comprised of an oxazine ring fused onto a quinoline system. http://purl.obolibrary.org/obo/CHEBI_5385 gliotoxin http://purl.obolibrary.org/obo/CHEBI_64130 pyrazinoindole A pyrazinoindole with a disulfide bridge spanning a dioxo-substituted pyrazine ring; mycotoxin produced by several species of fungi. http://purl.obolibrary.org/obo/CHEBI_55346 anidulafungin http://purl.obolibrary.org/obo/CHEBI_72588 semisynthetic derivative A semisynthetic echinocandin anti-fungal drug. It is active against Aspergillus and Candida species and is used for the treatment of invasive candidiasis. http://purl.obolibrary.org/obo/CHEBI_582124 myriocin http://purl.obolibrary.org/obo/CHEBI_59755 alpha-amino fatty acid An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity. http://purl.obolibrary.org/obo/CHEBI_59755 alpha-amino fatty acid http://purl.obolibrary.org/obo/CHEBI_83925 non-proteinogenic alpha-amino acid A fatty acid with an amino substituent at position C-2. http://purl.obolibrary.org/obo/CHEBI_64130 pyrazinoindole http://purl.obolibrary.org/obo/CHEBI_38101 organonitrogen heterocyclic compound An organic heterotricyclic compound comprising a pyrazine ring fused to an indole ring system. http://purl.obolibrary.org/obo/CHEBI_65077 neomycin C(6+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the six free amino groups of neomycin C; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_9242 spiroxamine http://purl.obolibrary.org/obo/CHEBI_72600 spiroketal The spiroketal resulting from the formal condensation of 4-tert-butylcyclohexanone with 3-[ethyl(propyl)amino]propane-1,2-diol. An inhibitor of ergosterol synthesis, it is a broad spectrum agricultural fungicide used particularly against powdery mildew in the production of cereals, bananas and grapes. http://purl.obolibrary.org/obo/CHEBI_64355 posaconazole http://purl.obolibrary.org/obo/CHEBI_87101 triazole antifungal drug An N-arylpiperazine that consists of piperazine carrying two 4-substituted phenyl groups at positions 1 and 4. A triazole antifungal drug. http://purl.obolibrary.org/obo/CHEBI_64766 cationic group http://purl.obolibrary.org/obo/CHEBI_24433 group A group that carries an overall positive charge. http://purl.obolibrary.org/obo/CHEBI_64767 anionic group http://purl.obolibrary.org/obo/CHEBI_24433 group A group that carries an overall negative charge. http://purl.obolibrary.org/obo/CHEBI_64898 anionic amino-acid residue http://purl.obolibrary.org/obo/CHEBI_64775 organic anionic group An amino-acid residue carrying an overall negative charge. http://purl.obolibrary.org/obo/CHEBI_65076 neamine(4+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of the four free amino groups of neamine; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_76733 EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*). http://purl.obolibrary.org/obo/CHEBI_76816 EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor http://purl.obolibrary.org/obo/CHEBI_76668 EC 2.7.* (P-containing group transferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category. http://purl.obolibrary.org/obo/CHEBI_8489 propiconazole http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide The cyclic ketal obtained by formal condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. A triazole fungicide, it is used commercially as a diastereoisomeric mixture on soft fruit (including apricots, peaches, nectarines, plums and prunes), nuts (including peanuts, pecans and almonds), mushrooms, and grasses grown for seeds. http://purl.obolibrary.org/obo/CHEBI_75596 EC 5.* (isomerase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*). http://purl.obolibrary.org/obo/CHEBI_75787 prokaryotic metabolite http://purl.obolibrary.org/obo/CHEBI_25212 metabolite Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea. http://purl.obolibrary.org/obo/CHEBI_7660 nystatin http://purl.obolibrary.org/obo/CHEBI_48121 polyene A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections. http://purl.obolibrary.org/obo/CHEBI_76661 EC 2.3.* (acyltransferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*). http://purl.obolibrary.org/obo/CHEBI_76697 EC 5.99.* (other isomerases) inhibitor http://purl.obolibrary.org/obo/CHEBI_75596 EC 5.* (isomerase) inhibitor An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*). http://purl.obolibrary.org/obo/CHEBI_76710 EC 4.* (lyase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C‒C, C‒O, C‒N and other bonds by other means than by hydrolysis or oxidation. http://purl.obolibrary.org/obo/CHEBI_76712 EC 4.2.* (C-O lyase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76710 EC 4.* (lyase) inhibitor A lyase inhibitor which inhibits the action of a C‒O lyase (EC 4.2.*.*). http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor http://purl.obolibrary.org/obo/CHEBI_23924 enzyme inhibitor An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*). http://purl.obolibrary.org/obo/CHEBI_76727 EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*). http://purl.obolibrary.org/obo/CHEBI_76729 EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*). http://purl.obolibrary.org/obo/CHEBI_76731 EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*). http://purl.obolibrary.org/obo/CHEBI_76736 EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*). http://purl.obolibrary.org/obo/CHEBI_76738 EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*). http://purl.obolibrary.org/obo/CHEBI_76740 EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*. http://purl.obolibrary.org/obo/CHEBI_76741 EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor http://purl.obolibrary.org/obo/CHEBI_76725 EC 1.* (oxidoreductase) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*). http://purl.obolibrary.org/obo/CHEBI_76764 EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor http://purl.obolibrary.org/obo/CHEBI_76759 EC 3.* (hydrolase) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*). http://purl.obolibrary.org/obo/CHEBI_76834 EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor http://purl.obolibrary.org/obo/CHEBI_71300 EC 2.* (transferase) inhibitor An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*). http://purl.obolibrary.org/obo/CHEBI_77053 closantel http://purl.obolibrary.org/obo/CHEBI_60911 racemate A racemate comprising equimolar amounts of (R)- and (S)-clostanel. An anthelmintic, it is used (as the dihydrate of the sodium salt) in veterinary medicine for the treatment of fluke and nematode infections. http://purl.obolibrary.org/obo/CHEBI_77054 N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide http://purl.obolibrary.org/obo/CHEBI_37142 organoiodine compound An aromatic amide resulting from the formal condensation of the carboxy group of 3,5-diiodosalicylic acid with the amino group of aniline substituted at positions 2, 4, and 5 by methyl, (4-chlorophenyl)(cyano)methyl, and methyl groups respectively. http://purl.obolibrary.org/obo/CHEBI_77056 (R)-closantel http://purl.obolibrary.org/obo/CHEBI_77054 N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide An N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide that has R configuration. http://purl.obolibrary.org/obo/CHEBI_77057 (S)-closantel http://purl.obolibrary.org/obo/CHEBI_77054 N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide An N-{5-chloro-4-[(4-chlorophenyl)(cyano)methyl]-2-methylphenyl}-2-hydroxy-3,5-diiodobenzamide that has S configuration. http://purl.obolibrary.org/obo/CHEBI_83955 2-saturated fatty acid anion http://purl.obolibrary.org/obo/CHEBI_28868 fatty acid anion A fatty acid anion obtained by deprotonation of the carboxy group of any 2-saturated fatty acid. http://purl.obolibrary.org/obo/CHEBI_83291 1-[3-(4-tert-butylphenyl)-2-methylpropyl]piperidine http://purl.obolibrary.org/obo/CHEBI_26151 piperidines A member of the class of piperidines that is N-isobutylpiperidine in which a hydrogen of one of the methyl groups is replaced by a p-tert-butylphenyl group. http://purl.obolibrary.org/obo/CHEBI_83297 4-dodecyl-2,6-dimethylmorpholine http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a dodecyl group. The configuration at positions 2 and 6 is unknown or unspecified. http://purl.obolibrary.org/obo/CHEBI_83365 2,6-dimethyl-4-tridecylmorpholine http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a tridecyl group. The configuration at positions 2 and 6 is unknown or unspecified. http://purl.obolibrary.org/obo/CHEBI_83368 2,6-dimethyl-4-undecylmorpholine http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by an undecyl group. The configuration at positions 2 and 6 is unknown or unspecified. http://purl.obolibrary.org/obo/CHEBI_83370 2,6-dimethyl-4-tetradecylmorpholine http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a tetradecyl group. The configuration at positions 2 and 6 is unknown or unspecified. http://purl.obolibrary.org/obo/CHEBI_83628 N-acylammonia http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A carboxamide obtained by the formal condensation of the carboxy group of any carboxylic acid with ammonia. http://purl.obolibrary.org/obo/CHEBI_83686 (2-chlorophenyl)(4-chlorophenyl)pyrimidin-5-ylmethanol http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes A member of the class of pyrimidines that is pyrimidin-5-ylmethanol in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 2-chlorophenyl group while the other is replaced by a 4-chlorophenyl group. http://purl.obolibrary.org/obo/CHEBI_83707 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol http://purl.obolibrary.org/obo/CHEBI_83575 monofluorobenzenes A tertiary alcohol that is ethanol in which one of the hydrogens at position 1 is replaced by an p-fluorophenyl group, the other hydrogen at position 1 is replaced by a p-fluorophenyl group, and one of the hydrogens at position 2 is replaced by a 1H-1,2,4-triazol-1-yl group. http://purl.obolibrary.org/obo/CHEBI_83732 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione http://purl.obolibrary.org/obo/CHEBI_55374 oxazolidinone A member of the class of oxazolidinones that is 5-ethenyl-5-methyl-2,4-oxazolidinedione in which the imide hydrogen is replaced by a 3,5-dichlorophenyl group. http://purl.obolibrary.org/obo/CHEBI_83733 (R)-vinclozolin http://purl.obolibrary.org/obo/CHEBI_83732 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (R)-enantiomer of vinclozolin. http://purl.obolibrary.org/obo/CHEBI_83735 (S)-vinclozolin http://purl.obolibrary.org/obo/CHEBI_83732 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione A 3-(3,5-dichlorophenyl)-5-ethenyl-5-methyl-2,4-oxazolidinedione that is the (S)-enantiomer of vinclozolin. http://purl.obolibrary.org/obo/CHEBI_83748 2-(4-chlorophenyl)-3-cyclopropyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol http://purl.obolibrary.org/obo/CHEBI_51454 cyclopropanes A tertiary alcohol that is butan-2-ol substituted by a 4-chlorophenyl group at position 2, a cyclopropyl group at position 3 and a 1H-1,2,4-triazol-1-yl group at position 1. http://purl.obolibrary.org/obo/CHEBI_83758 1-{[3-(2-chlorophenyl)-2-(4-fluorophenyl)oxiran-2-yl]methyl}-1H-1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes An epoxide that is oxirane substituted by a 2-chlorophenyl, 4-fluorophenyl and a 1H-1,2,4-triazol-1-ylmethyl groups. http://purl.obolibrary.org/obo/CHEBI_83779 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol http://purl.obolibrary.org/obo/CHEBI_83403 monochlorobenzenes A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively. http://purl.obolibrary.org/obo/CHEBI_83909 (1E)-1-(2,4-dichlorophenyl)-4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol http://purl.obolibrary.org/obo/CHEBI_78840 olefinic compound A member of the class of triazoles that is 4,4-dimethyl-2-(1,2,4-triazol-1-yl)pent-1-en-3-ol substituted at position 1 by a 2,4-dichlorophenyl group. http://purl.obolibrary.org/obo/CHEBI_84002 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one http://purl.obolibrary.org/obo/CHEBI_141498 hemiaminal ether A member of the class of triazoles that is 1-hydroxy-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one in which the hydroxyl hydrogen is replaced by a 4-chlorophenyl group. http://purl.obolibrary.org/obo/CHEBI_84003 (R)-triadimefon http://purl.obolibrary.org/obo/CHEBI_84002 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (R)-enantiomer of triadimefon. http://purl.obolibrary.org/obo/CHEBI_84004 (S)-triadimefon http://purl.obolibrary.org/obo/CHEBI_84002 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one A 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one that is the (S)-enantiomer of triadimefon. http://purl.obolibrary.org/obo/CHEBI_8434 prochloraz http://purl.obolibrary.org/obo/CHEBI_60600 amide fungicide A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables. http://purl.obolibrary.org/obo/CHEBI_9665 triadimefon http://purl.obolibrary.org/obo/CHEBI_87100 triazole fungicide A racemate comprising equal amounts of (R)- and (S)-triadimefon. A fungicide used to control powdery mildew, rusts and other infections in crops. http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection http://purl.obolibrary.org/obo/GO_0042995 cell projection A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/PATO_0045047 normal resistance to http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A resistance to a stimulus which is relatively normal or average http://purl.obolibrary.org/obo/PATO_0045054 normal length http://purl.obolibrary.org/obo/PATO_0045050 normal size A length quality which is relatively normal or average http://purl.obolibrary.org/obo/GO_0062012 regulation of small molecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the rate, frequency or extent of a small molecule metabolic process. http://purl.obolibrary.org/obo/GO_0110116 regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor cell differentiation Any process that modulates the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://purl.obolibrary.org/obo/GO_0110117 positive regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046534 positive regulation of photoreceptor cell differentiation Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://purl.obolibrary.org/obo/GO_0110118 negative regulation of compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046533 negative regulation of photoreceptor cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor cell differentiation. http://purl.obolibrary.org/obo/GO_0120187 positive regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin Any process that activates or increases the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_0140236 translation at presynapse http://purl.obolibrary.org/obo/GO_0140241 translation at synapse Translation that occurs at the presynapse. http://purl.obolibrary.org/obo/GO_0140237 translation at presynapse, modulating chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0140236 translation at presynapse Translation that occurs at the presynapse, and that modulates chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0140239 postsynaptic endocytosis http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse A vesicle-mediated transport process in which the postsynapse take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. http://purl.obolibrary.org/obo/GO_0140241 translation at synapse http://purl.obolibrary.org/obo/GO_0006412 translation Translation that occurs at the synapse. http://purl.obolibrary.org/obo/GO_0140242 translation at postsynapse http://purl.obolibrary.org/obo/GO_0140241 translation at synapse Translation that occurs at the postsynapse. http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that regulates translation occurring at the synapse. http://purl.obolibrary.org/obo/GO_0140245 regulation of translation at postsynapse http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse Any process that regulates translation occurring at the postsynapse. http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a protein at a synapse. http://purl.obolibrary.org/obo/GO_0140247 protein catabolic process at presynapse http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse The chemical reactions and pathways resulting in the breakdown of a protein at a presynapse. http://purl.obolibrary.org/obo/GO_0140249 protein catabolic process at postsynapse http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse The chemical reactions and pathways resulting in the breakdown of a protein at a postsynapse. http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the synapse. http://purl.obolibrary.org/obo/GO_0140251 regulation protein catabolic process at presynapse http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the presynapse. http://purl.obolibrary.org/obo/GO_0140252 regulation protein catabolic process at postsynapse http://purl.obolibrary.org/obo/GO_0140250 regulation protein catabolic process at synapse Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein at the postsynapse. http://purl.obolibrary.org/obo/PHIPO_0001140 host PAMP-triggered immunity signaling activated by pathogen present http://purl.obolibrary.org/obo/PHIPO_0001246 host PAMP-triggered immunity activated by pathogen present A cell signaling pathway phenotype where the host pattern recognition receptor signaling pathway is directly induced by a pathogen. This can include any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to a pathogen-derived physiological ligand. PRR ligands are usually referred to as pathogen-associated molecular pattern (PAMPs) or microbe-associated molecular pattern (MAMPs), structures conserved among microbial species (GO:0002221). http://purl.obolibrary.org/obo/PHIPO_0001142 normal pathogen protein localization to host chloroplast http://purl.obolibrary.org/obo/PHIPO_0001175 normal pathogen protein localization within host A pathogen host interaction phenotype in which the localization of a pathogen protein to the host chloroplast is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001143 abolished pathogen protein localization to host chloroplast http://purl.obolibrary.org/obo/PHIPO_0000246 abolished pathogen protein localization within host A pathogen host interaction phenotype in which the localization of a pathogen protein to the host chloroplast is abolished (i.e.the protein was localized to the host chloroplast and now is not). http://purl.obolibrary.org/obo/PHIPO_0001144 decreased level of host defense-related RNA involved in a pathogen interaction http://purl.obolibrary.org/obo/PHIPO_0001174 decreased level of host defense-induced RNA A pathogen host interaction phenotype, in which the level of host defense-related RNA usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001145 effector-mediated suppression of host effector triggered immunity present http://purl.obolibrary.org/obo/PHIPO_0001176 effector-mediated immune suppression phenotype A phenotype where the process of host tissue cell death causing a host lesion initially induced by the host activating its own hypersensitive response in defense, is subsequently suppressed by a pathogen effector. http://purl.obolibrary.org/obo/PHIPO_0001147 cellular metabolic process phenotype http://purl.obolibrary.org/obo/PHIPO_0000492 metabolic process phenotype A single organism phenotype that affects the chemical reactions and pathways by which individual cells transform chemical substances. (GO:0044237) http://purl.obolibrary.org/obo/PHIPO_0001148 unaltered reactive oxygen species production http://purl.obolibrary.org/obo/PHIPO_0001147 cellular metabolic process phenotype A single species metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) is unaltered.(GO:1903409) http://purl.obolibrary.org/obo/PHIPO_0001149 decreased reactive oxygen species production http://purl.obolibrary.org/obo/PHIPO_0001147 cellular metabolic process phenotype A single species metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) is decreased.(GO:1903409) http://purl.obolibrary.org/obo/PHIPO_0001150 abnormal spatial extent of reactive oxygen species production http://purl.obolibrary.org/obo/PHIPO_0001094 abnormal localization A single species localization phenotype in which ROS are produced over a different portion of the cell than normal. http://purl.obolibrary.org/obo/PHIPO_0001151 normal host size during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0001005 normal host morphology during pathogen invasion A host morphology phenotype where the size of the host is normal (indistinguishable from wild type) during pathogen invasion. http://purl.obolibrary.org/obo/PHIPO_0001152 increased host membrane blebbing during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0001006 abnormal host morphology during pathogen invasion A pathogen host interaction phenotype where the morphology of the host plasma membrane has increased blebbing during pathogen invasion. http://purl.obolibrary.org/obo/PHIPO_0001153 hyphal hyper branching http://purl.obolibrary.org/obo/PHIPO_0001427 abnormal hyphal branching A single species cell morphology phenotype in which fungal hyphae form an increased number of branches. http://purl.obolibrary.org/obo/GO_0120261 regulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_1902275 regulation of chromatin organization Any process that modulates the frequency, rate, extent or location of heterochromatin organization. http://purl.obolibrary.org/obo/GO_0120262 negative regulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_1905268 negative regulation of chromatin organization Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin organization. http://purl.obolibrary.org/obo/GO_0120263 positive regulation of heterochromatin organization http://purl.obolibrary.org/obo/GO_1905269 positive regulation of chromatin organization Any process that activates or increases the frequency, rate or extent of heterochromatin organization. http://purl.obolibrary.org/obo/GO_0120275 cerebral blood circulation http://purl.obolibrary.org/obo/GO_0008015 blood circulation The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products. http://purl.obolibrary.org/obo/GO_0120276 regulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of cerebral blood circulation. http://purl.obolibrary.org/obo/GO_0120277 positive regulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120276 regulation of cerebral blood circulation Any process that activates or increases the frequency, rate or extent of cerebral blood circulation. http://purl.obolibrary.org/obo/GO_0120278 negative regulation of cerebral blood circulation http://purl.obolibrary.org/obo/GO_0120276 regulation of cerebral blood circulation Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation. http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses Lamp5. http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron A transcriptomically distinct GABAergic neuron derived from the CGE and that expresses the vasoactive intestinal polypeptide. Its soma is located in the forebrain. http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron A transcriptomically distinct GABAergic neuron located in the cerebral cortex that expresses somatostatin (sst) and derived from the MGE. http://purl.obolibrary.org/obo/GO_0140572 vacuole fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a vacuole within a cell to form two or more separate vacuoles. http://purl.obolibrary.org/obo/CHEBI_190303 inorganic potassium salt http://purl.obolibrary.org/obo/CHEBI_167164 mineral nutrient A potassium salt that lacks C-H bonds http://purl.obolibrary.org/obo/CL_4023181 hypendymal cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A neurecto-epithelial cell that is part of the basal layer of the subcommissural organ and specializes in the secretion of proteins into the subarachnoid space. Hypendymal cells have similar characteristics to ependymal cells and express SCO-spondin. http://purl.obolibrary.org/obo/CL_4023068 thalamic excitatory neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain An excitatory neuron that has its soma located in the thalamic complex. This neuron type can be involved in a series of circuits related to sensory integration, motor integration, pain processing, social behaviour and reward response. http://purl.obolibrary.org/obo/CL_4030043 matrix D1 medium spiny neuron http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron A DRD1-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum. http://purl.obolibrary.org/obo/CL_4030047 matrix D2 medium spiny neuron http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A DRD2-expressing medium spiny neuron that is part of a matrix compartment of dorsal striatum. http://purl.obolibrary.org/obo/CL_4030048 striosomal D1 medium spiny neuron http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron A DRD1-expressing medium spiny neuron that is part of a striosome of dorsal striatum. http://purl.obolibrary.org/obo/CL_4030049 striosomal D2 medium spiny neuron http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A DRD2-expressing medium spiny neuron that is part of a striosome of dorsal striatum. http://purl.obolibrary.org/obo/CL_4030051 nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A DRD1-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle. http://purl.obolibrary.org/obo/CL_4030052 nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A DRD2-expressing medium spiny neuron that is part of a nucleus accumbens shell or olfactory tubercle. http://purl.obolibrary.org/obo/CL_4030053 Islands of Calleja granule cell http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A GABAergic neuron that resides in the islands of calleja and shows the cytoarchitectural and molecular features characteristic of this granule-like cell population. In mice and primates, it expresses D1 and D3 dopamine receptors (Drd1; Drd3), GABAergic markers (GAD1/2) and form densely packed granule cell clusters in the olfactory tubercle within the ventral striatum. Moreover it receives dense dopaminergic input from the VTA, and functionally associated with self-grooming behaviors and depression-like behaviors. http://purl.obolibrary.org/obo/CL_4030054 D1-NUDAP medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A DRD1-expressing medium spiny neuron that is part of dense, RXFP1-positive cell islands throughout the nucleus accumbens, putamen, and near the adjacent septal nuclei. http://purl.obolibrary.org/obo/UBERON_8480074 skin of gonad http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin part of some gonad. http://purl.obolibrary.org/obo/GO_0160093 chordate pharynx development http://purl.obolibrary.org/obo/GO_0060465 pharynx development The process whose specific outcome is the progression of cordate pharynx over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/CL_0008042 tanycyte of subfornical organ http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the subfornical organ (SFO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SFO, where they form a dense network surrounding these capillaries. http://purl.obolibrary.org/obo/CL_0008045 tanycyte of subcommissural organ http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the subcommisural organ (SCO). These cells extend long and slender fibers extending from their cell bodies in the ependyma toward fenestrated capillaries associated with the SCO, where they form a dense network surrounding these capillaries. http://purl.obolibrary.org/obo/CL_0008053 circumventricular organ capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell A capillary endothelial cell that is part of the circumventricular organs (CVOs), characterized by fenestrations that facilitate selective permeability to molecules, distinguishing it from the non-fenestrated endothelial cells of the blood-brain barrier. This cell is integral to the unique vascular structure of CVOs, which lack a traditional blood-brain barrier. It enables bidirectional exchange of polar molecules between blood and neural tissue, supporting neuroendocrine signaling, fluid balance, and immune responses. It is marked by the expression of PLVAP, a component of the fenestral diaphragm, in both rodents and humans. http://purl.obolibrary.org/obo/CL_0008055 respiratory tract secretory epithelial cell http://purl.obolibrary.org/obo/CL_0002368 respiratory tract epithelial cell A secretory epithelial cell of the respiratory tract epithelium. These cells have an endodermal origin. http://purl.obolibrary.org/obo/CL_4052045 steroidogenic stromal cell of ovary http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary A stromal cell that is part of the ovarian stroma, characterized by its ability to synthesize steroid hormones. http://purl.obolibrary.org/obo/CL_4307133 BAM NN_1 Mrc1 border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus). It is distinguished from other BAM NN cells by expression of Mrc1, Pf4. These cells are located in the Medulla, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5313 BAM NN_1. http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Itih3 (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1160 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4307049 Astro-TE NN_5 Hs3st3a1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Hs3st3a1 (Mmus), Sfrp1 (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Hs3st3a1, Sfrp1. These cells are located in the Olfactory areas, brain , in or close to the regions: Anterior olfactory nucleus, corpus callosum, body, lateral ventricle, corpus callosum, anterior forceps . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5229 Astro-TE NN_5. http://purl.obolibrary.org/obo/CL_4307114 ABC NN_1 Dapl1 arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc47a1 (Mmus), Dapl1 (Mmus). It is distinguished from other ABC NN cells by expression of Dapl1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5294 ABC NN_1. http://purl.obolibrary.org/obo/CL_4307037 Astro-NT NN_2 Gm30524 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), A330076C08Rik (Mmus), Fbln5 (Mmus), Mdga2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Gm30524. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5217 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4301585 CB Granule Glut_2 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Gap43 (Mmus), Rab37 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1155 CB Granule Glut_2. http://purl.obolibrary.org/obo/CL_4307110 OEC NN_1 Gdpd4 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Aqp1 (Mmus), Cldn5 (Mmus). It is distinguished from other OEC cells by expression of Gdpd4, Cldn5. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5290 OEC NN_1. http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Ccdc170 (Mmus), Nkx2-4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1173 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ednrb (Mmus), Hs3st3a1 (Mmus), C230072F16Rik (Mmus), Gria2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1168 Astro-OLF NN_3. http://purl.obolibrary.org/obo/CL_4306992 DCO Il22 Gly-Gaba_2 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Edaradd (Mmus). It is distinguished from other DCO Il22 Gly-Gaba cells by expression of Ppp1r17. It is GABAergic and glycinergic (inferred from expression of Slc32a1, Hdc, Slc6a5, Gad2, Gad1). These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Paraflocculus, arbor vitae, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5172 DCO Il22 Gly-Gaba_2. http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Maf (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1195 BAM NN_1. http://purl.obolibrary.org/obo/UBERON_0016514 cavity of left ventricle http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber Luminal space of the left ventricle of the heart. http://purl.obolibrary.org/obo/GO_0005776 autophagosome http://purl.obolibrary.org/obo/GO_0005773 vacuole A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the lytic vacuole/lysosome for degradation as part of macroautophagy. http://purl.obolibrary.org/obo/UBERON_0007831 pectoral girdle skeleton http://purl.obolibrary.org/obo/UBERON_0010719 girdle skeleton A subdivision of a limb or fin skeleton consisting of bones which connects the upper limb or fin to the axial skeleton on each side. It consists of the clavicle and scapula in humans and, in those species with three bones in the pectoral girdle, the coracoid. Some mammalian species (e.g. the dog and the horse) have only the scapula. In humans, the only joints between the shoulder girdle and axial skeleton are the sternoclavicular joints on each side. No joint exists between each scapula and the rib cage; instead the muscular connection between the two permits relatively great mobility of the shoulder girdle in relation to the pelvic girdle. In those species having only the scapula, no joint exists between the forelimb and the thorax, the only attachment being muscular[WP]. Examples: There are only two instances, right and left pectoral girdle skeletons. http://purl.obolibrary.org/obo/GO_0120006 regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/GO_0120007 negative regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/GO_0120008 positive regulation of glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of glutamatergic neuron differentiation. http://purl.obolibrary.org/obo/GO_1905962 glutamatergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glutamatergic neuron. http://purl.obolibrary.org/obo/CHEBI_139492 sensitiser http://purl.obolibrary.org/obo/CHEBI_52209 aetiopathogenetic role A chemical compound that causes a substantial proportion of exposed people or animals to develop an allergic reaction in normal tissue after repeated exposure to the compound. http://purl.obolibrary.org/obo/GO_0110077 vesicle-mediated intercellular transport http://purl.obolibrary.org/obo/GO_0010496 intercellular transport A cellular transport process in which transported substances are moved in extracellular vesicles between cells; transported substances are enclosed in the vesicle lumen or located in the extracellular vesicle membrane. http://purl.obolibrary.org/obo/GO_0150031 regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/GO_0150032 positive regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/GO_0150033 negative regulation of protein localization to lysosome http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to lysosome. http://purl.obolibrary.org/obo/GO_0061982 meiosis I cell cycle process http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process that contributes to the first meiotic division. The first meiotic division is the reductive division resulting in the separation of homologous chromosome pairs. http://purl.obolibrary.org/obo/GO_0061983 meiosis II cell cycle process http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process A process that coontributes to the second meiotic division. The second meiotic division separates chromatids resulting in a haploid number of chromosomes. http://purl.obolibrary.org/obo/CHEBI_139588 alpha-hydroxy ketone http://purl.obolibrary.org/obo/CHEBI_17087 ketone A ketone containing a hydroxy group on the α-carbon relative to the C=O group. http://purl.obolibrary.org/obo/CHEBI_140190 calcium-dependent antibiotics http://purl.obolibrary.org/obo/CHEBI_33281 antimicrobial agent Any antimicrobial agent whose activity is dependent on the presence of calcium ions. http://purl.obolibrary.org/obo/CHEBI_140345 hydroxy polyunsaturated fatty acid http://purl.obolibrary.org/obo/CHEBI_26208 polyunsaturated fatty acid Any polyunsaturated fatty acid carrying one or more hydroxy substituents. http://purl.obolibrary.org/obo/GO_0150077 regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that modulates the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/CHEBI_171664 antiamoebic agent http://purl.obolibrary.org/obo/CHEBI_35442 antiparasitic agent An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae. http://purl.obolibrary.org/obo/PATO_0070060 quality of interaction of a substance with electromagnetic radiation http://purl.obolibrary.org/obo/PATO_0002198 quality of a substance A quality of a substance on which or through which electromagnetic radiation impinges or traverses with respect to radiation. This substance quality changes the quality of the incident radiation with respect to any of: intensity, direction, scatter and wavelength. http://purl.obolibrary.org/obo/CL_4023059 committed oligodendrocyte precursor http://purl.obolibrary.org/obo/CL_0000123 neuron associated cell (sensu Vertebrata) An oligodendrocyte precursor cell that is committed to differentiate. http://purl.obolibrary.org/obo/UBERON_8600006 visceral striated muscle tissue http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue A striated muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/CL_4033015 retinal astrocyte http://purl.obolibrary.org/obo/CL_0009004 retinal cell A star-shaped glial cell that is part of some retina. This cell links neurons to blood vessels and may provide structural and physiological support to optic nerve head axons. http://purl.obolibrary.org/obo/PHIPO_0001304 resistance to salt stress http://purl.obolibrary.org/obo/PHIPO_0001302 resistance to osmotic stress A growth phenotype which describes the resistance of individuals or populations after exposure to a salt stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). http://purl.obolibrary.org/obo/PHIPO_0001305 resistance to non-ionic osmotic stress http://purl.obolibrary.org/obo/PHIPO_0001302 resistance to osmotic stress A growth phenotype which describes the resistance of individuals or populations after exposure to a non-ionic osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. http://purl.obolibrary.org/obo/PHIPO_0001306 sensitive to salt stress http://purl.obolibrary.org/obo/PHIPO_0001303 sensitive to osmotic stress A growth phenotype which describes the sensitivity of individuals or populations after exposure to a salt stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. http://purl.obolibrary.org/obo/PHIPO_0001307 sensitive to non-ionic osmotic stress http://purl.obolibrary.org/obo/PHIPO_0001303 sensitive to osmotic stress A growth phenotype which describes the sensitivity of individuals or populations after exposure to a non-ionic osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. http://purl.obolibrary.org/obo/UBERON_0003071 eye primordium http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure Portion of tissue that is part of the anterior neural keel and will form the optic vesicle[ZFA]. A paired ectodermal placode that becomes invaginated to form the embryonic lens vesicles. http://purl.obolibrary.org/obo/GO_0099156 cell-cell signaling via exosome http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling in which the ligand is carried between cells by an exosome. http://purl.obolibrary.org/obo/GO_0099157 trans-synaptic signaling via exosome http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Transynaptic signaling in which the ligand is carried across the synapse by an exosome. http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling Any process that modulates the frequency, rate or extent of trans-synaptic signaling. http://purl.obolibrary.org/obo/GO_0099173 postsynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a postsynapse. http://purl.obolibrary.org/obo/GO_0099174 regulation of presynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a presynapse. http://purl.obolibrary.org/obo/GO_0099187 presynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures and their associated proteins in the presynaptic cytoskeleton. http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising cytoskeletal filaments and their associated proteins in the postsynaptic cytoskeleton. http://purl.obolibrary.org/obo/CHEBI_141153 quinone outside inhibitor http://purl.obolibrary.org/obo/CHEBI_38499 mitochondrial cytochrome-bc1 complex inhibitor A mitochondrial cytochrome-bc1 complex inhibitor that acts at the Quinone 'outer' (Qo) binding site of the cytochrome-bc1 complex. http://purl.obolibrary.org/obo/GO_0140253 cell-cell fusion http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. http://purl.obolibrary.org/obo/PHIPO_0000935 decreased cell wall integrity http://purl.obolibrary.org/obo/PHIPO_0000925 abnormal cell wall organization or biogenesis A cellular process phenotype in which the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall is decreased. http://purl.obolibrary.org/obo/PHIPO_0000936 cell lysis http://purl.obolibrary.org/obo/PHIPO_0001222 cell viability phenotype An single species phenotype in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. http://purl.obolibrary.org/obo/PHIPO_0000937 asexual spore lysis present http://purl.obolibrary.org/obo/PHIPO_0000936 cell lysis An single species phenotype in which an asexual spore lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. http://purl.obolibrary.org/obo/PHIPO_0000938 vegetative cell lysis http://purl.obolibrary.org/obo/PHIPO_0000936 cell lysis An single species phenotype in which a vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. http://purl.obolibrary.org/obo/PHIPO_0000939 asexual spore lysis absent http://purl.obolibrary.org/obo/PHIPO_0000936 cell lysis An single species phenotype in which an asexual spore does not lyse, i.e. the plasma membrane ruptures and cytoplasm is lost. http://purl.obolibrary.org/obo/PHIPO_0000940 abnormal germ tube http://purl.obolibrary.org/obo/PHIPO_0000415 abnormal subcellular component A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is abnormal. (GO:0032179) http://purl.obolibrary.org/obo/PHIPO_0000941 short germ tube http://purl.obolibrary.org/obo/PHIPO_0000940 abnormal germ tube A single species phenotype where the slender tubular outgrowth first produced by most spores in germination is shorter than normal. (GO:0032179) http://purl.obolibrary.org/obo/PHIPO_0000943 sensitive to hydrogen peroxide http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to hydrogen peroxide. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell http://purl.obolibrary.org/obo/PHIPO_0000404 abnormal cell phenotype A single species cell phenotype in which the amount of a specific substance measured in a cell differs from normal. http://purl.obolibrary.org/obo/PHIPO_0000945 altered cellular reactive oxygen species level http://purl.obolibrary.org/obo/PHIPO_0000944 altered level of substance in cell A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell differs from normal. http://purl.obolibrary.org/obo/PHIPO_0000946 decreased cellular reactive oxygen species level http://purl.obolibrary.org/obo/PHIPO_0000945 altered cellular reactive oxygen species level A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0000947 increased cellular reactive oxygen species level http://purl.obolibrary.org/obo/PHIPO_0000945 altered cellular reactive oxygen species level A single species cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal. http://purl.obolibrary.org/obo/CHEBI_173084 ferroptosis inhibitor http://purl.obolibrary.org/obo/CHEBI_52206 biochemical role Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. http://purl.obolibrary.org/obo/CL_4030029 blood lymphocyte http://purl.obolibrary.org/obo/CL_2000001 peripheral blood mononuclear cell A lymphocyte located in blood. http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron A GABAergic interneuron whose soma is located in the cerebellar cortex. http://purl.obolibrary.org/obo/CL_4023063 medial ganglionic eminence derived interneuron http://purl.obolibrary.org/obo/CL_0000099 interneuron An interneuron that is derived from the medial ganglionic eminence. http://purl.obolibrary.org/obo/UBERON_8480025 skin of clavicle region http://purl.obolibrary.org/obo/UBERON_0000014 zone of skin A zone of skin that is above the clavicle zone in the pectoral girdle region. http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A Purkinje cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pcp2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:313 CBX Purkinje Gaba. http://purl.obolibrary.org/obo/PHIPO_0001450 resistance to sodium dodecyl sulfate http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to sodium dodecyl sulfate (SDS). Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001451 sensitive to acidity http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress A cell phenotype in which cells grow to a lower extent than wild type following exposure to acidic pH. http://purl.obolibrary.org/obo/GO_0000001 mitochondrion inheritance http://purl.obolibrary.org/obo/GO_0048311 mitochondrion distribution The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. http://purl.obolibrary.org/obo/GO_0000003 obsolete reproduction http://purl.obolibrary.org/obo/GO_0008150 biological process OBSOLETE. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. http://purl.obolibrary.org/obo/GO_0000011 vacuole inheritance http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. http://purl.obolibrary.org/obo/GO_0000045 autophagosome assembly http://purl.obolibrary.org/obo/GO_1905037 autophagosome organization The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm. http://purl.obolibrary.org/obo/GO_0000048 peptidyltransferase activity http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2). This reaction is catalyzed by a ribozyme. http://purl.obolibrary.org/obo/GO_0000049 tRNA binding http://purl.obolibrary.org/obo/GO_0003723 RNA binding Binding to a transfer RNA. http://purl.obolibrary.org/obo/GO_0000070 mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets. http://purl.obolibrary.org/obo/GO_0000139 Golgi membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding any of the compartments of the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0000228 nuclear chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. http://purl.obolibrary.org/obo/GO_0000262 mitochondrial chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome found in the mitochondrion of a eukaryotic cell. http://purl.obolibrary.org/obo/GO_0000266 mitochondrial fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0000271 polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0000272 polysaccharide catabolic process http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0000278 mitotic cell cycle http://purl.obolibrary.org/obo/GO_0007049 cell cycle Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. http://purl.obolibrary.org/obo/GO_0000279 M phase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase. http://purl.obolibrary.org/obo/GO_0000280 nuclear division http://purl.obolibrary.org/obo/GO_0048285 organelle fission The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. http://purl.obolibrary.org/obo/GO_0000302 response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome http://purl.obolibrary.org/obo/GO_0005840 ribosome A ribosome contained within a subcellular membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole http://purl.obolibrary.org/obo/GO_0005773 vacuole A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases. http://purl.obolibrary.org/obo/GO_0000740 nuclear membrane fusion http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The joining of 2 or more lipid bilayer membranes that surround the nucleus. http://purl.obolibrary.org/obo/GO_0000741 karyogamy http://purl.obolibrary.org/obo/GO_0048284 organelle fusion The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. http://purl.obolibrary.org/obo/GO_0000768 syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0006949 syncytium formation The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0000785 chromatin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. http://purl.obolibrary.org/obo/GO_0000791 euchromatin http://purl.obolibrary.org/obo/GO_0000785 chromatin A dispersed and relatively uncompacted form of chromatin that is in a transcription-competent conformation. http://purl.obolibrary.org/obo/GO_0000792 heterochromatin http://purl.obolibrary.org/obo/GO_0000785 chromatin A compact and highly condensed form of chromatin that is refractory to transcription. http://purl.obolibrary.org/obo/GO_0000803 sex chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A chromosome involved in sex determination. http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The developmental process in which the size or shape of a cell is generated and organized. http://purl.obolibrary.org/obo/GO_0000957 mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0006401 RNA catabolic process The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. http://purl.obolibrary.org/obo/GO_0000959 mitochondrial RNA metabolic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. http://purl.obolibrary.org/obo/GO_0000960 regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/GO_0000961 negative regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/GO_0000962 positive regulation of mitochondrial RNA catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome. http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/GO_0001402 signal transduction involved in filamentous growth http://purl.obolibrary.org/obo/GO_0007165 signal transduction Relaying of environmental signals promoting filamentous growth. http://purl.obolibrary.org/obo/GO_0001501 skeletal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). http://purl.obolibrary.org/obo/GO_0001503 ossification http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0001507 acetylcholine catabolic process in synaptic cleft http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission. http://purl.obolibrary.org/obo/GO_0001508 action potential http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities. http://purl.obolibrary.org/obo/GO_0001525 angiogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility http://purl.obolibrary.org/obo/GO_0048870 cell motility Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. http://purl.obolibrary.org/obo/GO_0001555 oocyte growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/GO_0001556 oocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0001560 regulation of cell growth by extracellular stimulus http://purl.obolibrary.org/obo/GO_0001558 regulation of cell growth Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time. http://purl.obolibrary.org/obo/GO_0001568 blood vessel development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0001569 branching involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0001578 microtubule bundle formation http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that results in a parallel arrangement of microtubules. http://purl.obolibrary.org/obo/GO_0001653 peptide receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with an extracellular or intracellular peptide to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0001654 eye development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. http://purl.obolibrary.org/obo/GO_0001659 temperature homeostasis http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis A homeostatic process in which an organism modulates its internal body temperature. http://purl.obolibrary.org/obo/GO_0001664 G protein-coupled receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a G protein-coupled receptor. http://purl.obolibrary.org/obo/GO_0001666 response to hypoxia http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration Cell migration that is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0001674 female germ cell nucleus http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus The nucleus of the female germ cell, a reproductive cell in females. http://purl.obolibrary.org/obo/GO_0001677 formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/GO_0001700 embryonic development via the syncytial blastoderm http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0001701 in utero embryonic development http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the ectoderm, mesoderm and endoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001705 ectoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of ectoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001706 endoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The formation of the endoderm during gastrulation. http://purl.obolibrary.org/obo/GO_0001707 mesoderm formation http://purl.obolibrary.org/obo/GO_0001704 formation of primary germ layer The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0001739 sex chromatin http://purl.obolibrary.org/obo/GO_0000792 heterochromatin Chromatin that is part of a sex chromosome. http://purl.obolibrary.org/obo/GO_0001743 lens placode formation http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation The initial developmental process that will lead to the formation of an eye. http://purl.obolibrary.org/obo/GO_0001745 compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0001751 compound eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell. http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration http://purl.obolibrary.org/obo/GO_0090497 mesenchymal cell migration The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo. http://purl.obolibrary.org/obo/GO_0001756 somitogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/GO_0001763 morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. http://purl.obolibrary.org/obo/GO_0001764 neuron migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell. http://purl.obolibrary.org/obo/GO_0001768 establishment of T cell polarity http://purl.obolibrary.org/obo/GO_0001767 establishment of lymphocyte polarity The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. http://purl.obolibrary.org/obo/GO_0001773 myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0001774 microglial cell activation http://purl.obolibrary.org/obo/GO_0061900 glial cell activation The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0001775 cell activation http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process by which exposure to an activating factor such as a cellular or soluble ligand results in a change in the morphology or behavior of a cell. http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0001777 T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. http://purl.obolibrary.org/obo/GO_0001816 cytokine production http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate, or extent of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001818 negative regulation of cytokine production http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the rate of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001819 positive regulation of cytokine production http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of production of a cytokine. http://purl.obolibrary.org/obo/GO_0001820 serotonin secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesized in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. http://purl.obolibrary.org/obo/GO_0001824 blastocyst development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. The blastula follows the morula and precedes the gastrula in the developmental sequence. http://purl.obolibrary.org/obo/GO_0001825 blastocyst formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a blastocyst from a solid ball of cells known as a morula. http://purl.obolibrary.org/obo/GO_0001826 inner cell mass cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell. http://purl.obolibrary.org/obo/GO_0001829 trophectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. http://purl.obolibrary.org/obo/GO_0001831 trophectodermal cellular morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The morphogenesis of trophectoderm cells. http://purl.obolibrary.org/obo/GO_0001832 blastocyst growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. http://purl.obolibrary.org/obo/GO_0001833 inner cell mass cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the inner cell mass. http://purl.obolibrary.org/obo/GO_0001834 trophectodermal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The proliferation of cells in the trophectoderm. http://purl.obolibrary.org/obo/GO_0001837 epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The morphogenesis of an embryonic epithelium into a tube-shaped structure. http://purl.obolibrary.org/obo/GO_0001839 neural plate morphogenesis http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. http://purl.obolibrary.org/obo/GO_0001840 neural plate development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0001841 neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0001842 neural fold formation http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. http://purl.obolibrary.org/obo/GO_0001873 polysaccharide immune receptor activity http://purl.obolibrary.org/obo/GO_0038187 pattern recognition receptor activity Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0001885 endothelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The progression of an endothelial cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0001886 endothelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis http://purl.obolibrary.org/obo/GO_0060249 anatomical structure homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function. http://purl.obolibrary.org/obo/GO_0001932 regulation of protein phosphorylation http://purl.obolibrary.org/obo/GO_0042325 regulation of phosphorylation Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. http://purl.obolibrary.org/obo/GO_0001933 negative regulation of protein phosphorylation http://purl.obolibrary.org/obo/GO_0042326 negative regulation of phosphorylation Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. http://purl.obolibrary.org/obo/GO_0001934 positive regulation of protein phosphorylation http://purl.obolibrary.org/obo/GO_0042327 positive regulation of phosphorylation Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/GO_0001936 regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001937 negative regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001938 positive regulation of endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of endothelial cell proliferation. http://purl.obolibrary.org/obo/GO_0001941 postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). http://purl.obolibrary.org/obo/GO_0001944 vasculature development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. http://purl.obolibrary.org/obo/GO_0001955 blood vessel maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0001956 positive regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/GO_0001957 intramembranous ossification http://purl.obolibrary.org/obo/GO_0036072 direct ossification Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. http://purl.obolibrary.org/obo/GO_0001959 regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/GO_0001960 negative regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060761 negative regulation of response to cytokine stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/GO_0001961 positive regulation of cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0060760 positive regulation of response to cytokine stimulus Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway. http://purl.obolibrary.org/obo/GO_0001963 synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of dopamine. from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0001976 nervous system process involved in regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0050877 nervous system process The regulation of blood pressure mediated by detection of stimuli and a neurological response. http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone http://purl.obolibrary.org/obo/GO_0050886 endocrine process The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. http://purl.obolibrary.org/obo/GO_0001992 regulation of systemic arterial blood pressure by vasopressin http://purl.obolibrary.org/obo/GO_0001990 regulation of systemic arterial blood pressure by hormone The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport. http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. http://purl.obolibrary.org/obo/GO_0002011 morphogenesis of an epithelial sheet http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. http://purl.obolibrary.org/obo/GO_0002027 regulation of heart rate http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the frequency or rate of heart contraction. http://purl.obolibrary.org/obo/GO_0002036 regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane Any process that modulates the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/GO_0002037 negative regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/GO_0002038 positive regulation of L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport Any process that activates or increases the frequency, rate or extent of L-glutamate import into a cell. http://purl.obolibrary.org/obo/GO_0002052 positive regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation Any process that activates or increases the rate of neuroblast proliferation. http://purl.obolibrary.org/obo/GO_0002053 positive regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development http://purl.obolibrary.org/obo/GO_0002064 epithelial cell development The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002068 glandular epithelial cell development http://purl.obolibrary.org/obo/GO_0002066 columnar/cuboidal epithelial cell development The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. http://purl.obolibrary.org/obo/GO_0002070 epithelial cell maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. http://purl.obolibrary.org/obo/GO_0002071 glandular epithelial cell maturation http://purl.obolibrary.org/obo/GO_0002069 columnar/cuboidal epithelial cell maturation The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. http://purl.obolibrary.org/obo/GO_0002072 optic cup morphogenesis involved in camera-type eye development http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002085 inhibition of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/GO_0002087 regulation of respiratory gaseous exchange by nervous system process http://purl.obolibrary.org/obo/GO_0050877 nervous system process A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. http://purl.obolibrary.org/obo/GO_0002088 lens development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002089 lens morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002158 osteoclast proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes. http://purl.obolibrary.org/obo/GO_0002181 cytoplasmic translation http://purl.obolibrary.org/obo/GO_0006412 translation The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein. http://purl.obolibrary.org/obo/GO_0002182 cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_0006414 translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm. http://purl.obolibrary.org/obo/GO_0002183 cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_0006413 translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/GO_0002184 cytoplasmic translational termination http://purl.obolibrary.org/obo/GO_0006415 translational termination The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon. http://purl.obolibrary.org/obo/GO_0002213 defense response to insect http://purl.obolibrary.org/obo/GO_0051707 response to other organism A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism. http://purl.obolibrary.org/obo/GO_0002227 innate immune response in mucosa http://purl.obolibrary.org/obo/GO_0045087 innate immune response Any process of the innate immune response that takes place in the mucosal tissues. http://purl.obolibrary.org/obo/GO_0002232 leukocyte chemotaxis involved in inflammatory response http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of an immune cell in response to an external stimulus contributing to an inflammatory response. http://purl.obolibrary.org/obo/GO_0002233 leukocyte chemotaxis involved in immune response http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of an immune cell in response to an external stimulus a part of an immune response. http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells. http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response http://purl.obolibrary.org/obo/GO_0006955 immune response An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. http://purl.obolibrary.org/obo/GO_0002252 immune effector process http://purl.obolibrary.org/obo/GO_0002376 immune system process Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0002263 cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002252 immune effector process A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002264 endothelial cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042118 endothelial cell activation A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002265 astrocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0048143 astrocyte activation A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002269 leukocyte activation involved in inflammatory response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002277 myeloid dendritic cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002275 myeloid cell activation involved in immune response The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002280 monocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0042117 monocyte activation The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002281 macrophage activation involved in immune response http://purl.obolibrary.org/obo/GO_0042116 macrophage activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002282 microglial cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0002281 macrophage activation involved in immune response The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002284 myeloid dendritic cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0043011 myeloid dendritic cell differentiation The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response. http://purl.obolibrary.org/obo/GO_0002285 lymphocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002286 T cell activation involved in immune response http://purl.obolibrary.org/obo/GO_0042110 T cell activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002292 T cell differentiation involved in immune response http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. http://purl.obolibrary.org/obo/GO_0002309 T cell proliferation involved in immune response http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation The expansion of a T cell population by cell division as part of an immune response. http://purl.obolibrary.org/obo/GO_0002318 myeloid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages. http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0002244 hematopoietic progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages. http://purl.obolibrary.org/obo/GO_0002351 serotonin production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002366 leukocyte activation involved in immune response http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002369 T cell cytokine production http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity Any process that contributes to cytokine production by a T cell. http://purl.obolibrary.org/obo/GO_0002371 dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process that contributes to cytokine production by a dendritic cell. http://purl.obolibrary.org/obo/GO_0002372 myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production Any process that contributes to cytokine production by a myeloid dendritic cell. http://purl.obolibrary.org/obo/GO_0002376 immune system process http://purl.obolibrary.org/obo/GO_0008150 biological process Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. http://purl.obolibrary.org/obo/GO_0002385 mucosal immune response http://purl.obolibrary.org/obo/GO_0002251 organ or tissue specific immune response An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract. http://purl.obolibrary.org/obo/GO_0002396 MHC protein complex assembly http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002399 MHC class II protein complex assembly http://purl.obolibrary.org/obo/GO_0002396 MHC protein complex assembly The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex. http://purl.obolibrary.org/obo/GO_0002407 dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0036336 dendritic cell migration The movement of a dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002408 myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a myeloid dendritic cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002440 production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010467 gene expression The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002442 serotonin secretion involved in inflammatory response http://purl.obolibrary.org/obo/GO_0001820 serotonin secretion The regulated release of serotonin by a cell as part of an inflammatory response. http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002252 immune effector process Any process involved in the carrying out of an immune response by a leukocyte. http://purl.obolibrary.org/obo/GO_0002444 myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a myeloid leukocyte. http://purl.obolibrary.org/obo/GO_0002449 lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002443 leukocyte mediated immunity Any process involved in the carrying out of an immune response by a lymphocyte. http://purl.obolibrary.org/obo/GO_0002456 T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process involved in the carrying out of an immune response by a T cell. http://purl.obolibrary.org/obo/GO_0002457 T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002250 adaptive immune response An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002469 myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002468 dendritic cell antigen processing and presentation The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002471 monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002472 macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex. http://purl.obolibrary.org/obo/GO_0002520 immune system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0002521 leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/GO_0002522 leukocyte migration involved in immune response http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. http://purl.obolibrary.org/obo/GO_0002523 leukocyte migration involved in inflammatory response http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002534 cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0002532 production of molecular mediator involved in inflammatory response The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0002548 monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a monocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0002572 pro-T cell differentiation http://purl.obolibrary.org/obo/GO_0002320 lymphoid progenitor cell differentiation The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed. http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002578 negative regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002579 positive regulation of antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/GO_0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/GO_0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II http://purl.obolibrary.org/obo/GO_0002580 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II. http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002605 negative regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002606 positive regulation of dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002604 regulation of dendritic cell antigen processing and presentation Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002608 negative regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002609 positive regulation of myeloid dendritic cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002607 regulation of myeloid dendritic cell antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002614 negative regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002615 positive regulation of monocyte antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002613 regulation of monocyte antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002577 regulation of antigen processing and presentation Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002617 negative regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002618 positive regulation of macrophage antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002616 regulation of macrophage antigen processing and presentation Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002625 regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002626 negative regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002627 positive regulation of T cell antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation. http://purl.obolibrary.org/obo/GO_0002679 respiratory burst involved in defense response http://purl.obolibrary.org/obo/GO_0045730 respiratory burst A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response ; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002683 negative regulation of immune system process http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002684 positive regulation of immune system process http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the frequency, rate, or extent of an immune system process. http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/GO_0002686 negative regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/GO_0002687 positive regulation of leukocyte migration http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration Any process that activates or increases the frequency, rate, or extent of leukocyte migration. http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0002689 negative regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050922 negative regulation of chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0002690 positive regulation of leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002695 negative regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002696 positive regulation of leukocyte activation http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation Any process that activates or increases the frequency, rate, or extent of leukocyte activation. http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002682 regulation of immune system process Any process that modulates the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002698 negative regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002699 positive regulation of immune effector process http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that activates or increases the frequency, rate, or extent of an immune effector process. http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002701 negative regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002702 positive regulation of production of molecular mediator of immune response http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002697 regulation of immune effector process Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002704 negative regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002705 positive regulation of leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002707 negative regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002708 positive regulation of lymphocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002706 regulation of lymphocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002709 regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that modulates the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002710 negative regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002711 positive regulation of T cell mediated immunity http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002700 regulation of production of molecular mediator of immune response Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/GO_0002719 negative regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response. http://purl.obolibrary.org/obo/GO_0002720 positive regulation of cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response. http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/GO_0002725 negative regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/GO_0002726 positive regulation of T cell cytokine production http://purl.obolibrary.org/obo/GO_0002724 regulation of T cell cytokine production Any process that activates or increases the frequency, rate, or extent of T cell cytokine production. http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002731 negative regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002732 positive regulation of dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002730 regulation of dendritic cell cytokine production Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002733 regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002734 negative regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002735 positive regulation of myeloid dendritic cell cytokine production http://purl.obolibrary.org/obo/GO_0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production. http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002762 negative regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002763 positive regulation of myeloid leukocyte differentiation http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. http://purl.obolibrary.org/obo/GO_0002790 peptide secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a peptide from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport Any process that modulates the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002792 negative regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002793 positive regulation of peptide secretion http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion Any process that activates or increases the frequency, rate, or extent of peptide secretion. http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002820 negative regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002821 positive regulation of adaptive immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002819 regulation of adaptive immune response Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains http://purl.obolibrary.org/obo/GO_0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. http://purl.obolibrary.org/obo/GO_0002831 regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002832 negative regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002833 positive regulation of response to biotic stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002703 regulation of leukocyte mediated immunity Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002887 negative regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002888 positive regulation of myeloid leukocyte mediated immunity http://purl.obolibrary.org/obo/GO_0002886 regulation of myeloid leukocyte mediated immunity Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. http://purl.obolibrary.org/obo/GO_0002932 tendon sheath development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. http://purl.obolibrary.org/obo/GO_0003002 regionalization http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. http://purl.obolibrary.org/obo/GO_0003007 heart morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0003008 system process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. http://purl.obolibrary.org/obo/GO_0003009 skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. http://purl.obolibrary.org/obo/GO_0003012 muscle system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. http://purl.obolibrary.org/obo/GO_0003013 circulatory system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. http://purl.obolibrary.org/obo/GO_0003015 heart process http://purl.obolibrary.org/obo/GO_0003013 circulatory system process A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0003016 respiratory system process http://purl.obolibrary.org/obo/GO_0003008 system process A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0003044 regulation of systemic arterial blood pressure mediated by a chemical signal http://purl.obolibrary.org/obo/GO_0003073 regulation of systemic arterial blood pressure The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine. http://purl.obolibrary.org/obo/GO_0003073 regulation of systemic arterial blood pressure http://purl.obolibrary.org/obo/GO_0008217 regulation of blood pressure The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/GO_0003131 mesodermal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from mesodermal cells to endodermal cells. http://purl.obolibrary.org/obo/GO_0003133 endodermal-mesodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from endodermal cells to mesodermal cells. http://purl.obolibrary.org/obo/GO_0003142 cardiogenic plate morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. http://purl.obolibrary.org/obo/GO_0003143 embryonic heart tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/GO_0003144 embryonic heart tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. http://purl.obolibrary.org/obo/GO_0003145 embryonic heart tube formation via epithelial folding http://purl.obolibrary.org/obo/GO_0003144 embryonic heart tube formation The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis. http://purl.obolibrary.org/obo/GO_0003147 neural crest cell migration involved in heart formation http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation. http://purl.obolibrary.org/obo/GO_0003148 outflow tract septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. http://purl.obolibrary.org/obo/GO_0003149 membranous septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. http://purl.obolibrary.org/obo/GO_0003150 muscular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. http://purl.obolibrary.org/obo/GO_0003151 outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/GO_0003152 morphogenesis of an epithelial fold involved in embryonic heart tube formation http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation. http://purl.obolibrary.org/obo/GO_0003156 regulation of animal organ formation http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. http://purl.obolibrary.org/obo/GO_0003157 endocardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0003158 endothelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0003159 morphogenesis of an endothelium http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0003160 endocardium morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0003161 cardiac conduction system development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. http://purl.obolibrary.org/obo/GO_0003162 atrioventricular node development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. http://purl.obolibrary.org/obo/GO_0003163 sinoatrial node development http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. http://purl.obolibrary.org/obo/GO_0003164 His-Purkinje system development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0003165 Purkinje myocyte development http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. http://purl.obolibrary.org/obo/GO_0003168 Purkinje myocyte differentiation http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. http://purl.obolibrary.org/obo/GO_0003169 coronary vein morphogenesis http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis The process in which the anatomical structures of veins of the heart are generated and organized. http://purl.obolibrary.org/obo/GO_0003197 endocardial cushion development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003203 endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003204 cardiac skeleton development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003212 cardiac left atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the left cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/GO_0003213 cardiac right atrium morphogenesis http://purl.obolibrary.org/obo/GO_0003209 cardiac atrium morphogenesis The process in which the right cardiac atrium is generated and organized. http://purl.obolibrary.org/obo/GO_0003214 cardiac left ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the left cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/GO_0003215 cardiac right ventricle morphogenesis http://purl.obolibrary.org/obo/GO_0003208 cardiac ventricle morphogenesis The process in which the right cardiac ventricle is generated and organized. http://purl.obolibrary.org/obo/GO_0003216 cardiac left atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. http://purl.obolibrary.org/obo/GO_0003217 cardiac right atrium formation http://purl.obolibrary.org/obo/GO_0003210 cardiac atrium formation The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. http://purl.obolibrary.org/obo/GO_0003218 cardiac left ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/GO_0003219 cardiac right ventricle formation http://purl.obolibrary.org/obo/GO_0003211 cardiac ventricle formation The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. http://purl.obolibrary.org/obo/GO_0003220 left ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003221 right ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. http://purl.obolibrary.org/obo/GO_0003228 atrial cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003229 ventricular cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003230 cardiac atrium development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. http://purl.obolibrary.org/obo/GO_0003231 cardiac ventricle development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. http://purl.obolibrary.org/obo/GO_0003235 sinus venosus development http://purl.obolibrary.org/obo/GO_0003205 cardiac chamber development The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003236 sinus venosus morphogenesis http://purl.obolibrary.org/obo/GO_0003206 cardiac chamber morphogenesis The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003237 sinus venosus formation http://purl.obolibrary.org/obo/GO_0003207 cardiac chamber formation The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. http://purl.obolibrary.org/obo/GO_0003241 growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis Developmental growth that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003245 cardiac muscle tissue growth involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003248 heart capillary growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. http://purl.obolibrary.org/obo/GO_0003253 cardiac neural crest cell migration involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract. http://purl.obolibrary.org/obo/GO_0003260 cardioblast migration http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0003272 endocardial cushion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003273 cell migration involved in endocardial cushion formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003274 endocardial cushion fusion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping. http://purl.obolibrary.org/obo/GO_0003275 apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries. http://purl.obolibrary.org/obo/GO_0003277 apoptotic process involved in endocardial cushion morphogenesis http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. http://purl.obolibrary.org/obo/GO_0003278 apoptotic process involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of a cardiac septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003281 ventricular septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the ventricular septum over time from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003283 atrial septum development http://purl.obolibrary.org/obo/GO_0003279 cardiac septum development The progression of the atrial septum over time, from its initial formation to the mature structure. http://purl.obolibrary.org/obo/GO_0003292 cardiac septum cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which an endocardial cushion cell becomes a cell of a cardiac septum. http://purl.obolibrary.org/obo/GO_0003298 physiological muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. http://purl.obolibrary.org/obo/GO_0003301 physiological cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003300 cardiac muscle hypertrophy The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. http://purl.obolibrary.org/obo/GO_0003313 heart rudiment development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. http://purl.obolibrary.org/obo/GO_0003314 heart rudiment morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of the heart rudiment are generated and organized. http://purl.obolibrary.org/obo/GO_0003315 heart rudiment formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the heart rudiment. http://purl.obolibrary.org/obo/GO_0003330 regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003331 positive regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003332 negative regulation of extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The process in which an amino acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_0003341 cilium movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003342 proepicardium development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. http://purl.obolibrary.org/obo/GO_0003343 septum transversum development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. http://purl.obolibrary.org/obo/GO_0003344 pericardium morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the pericardium is generated and organized. http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell. http://purl.obolibrary.org/obo/GO_0003352 regulation of cilium movement http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003353 positive regulation of cilium movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003354 negative regulation of cilium movement http://purl.obolibrary.org/obo/GO_0003352 regulation of cilium movement Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. http://purl.obolibrary.org/obo/GO_0003357 noradrenergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline. http://purl.obolibrary.org/obo/GO_0003358 noradrenergic neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0003360 brainstem development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. http://purl.obolibrary.org/obo/GO_0003361 noradrenergic neuron differentiation involved in brainstem development http://purl.obolibrary.org/obo/GO_0003357 noradrenergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem. http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. http://purl.obolibrary.org/obo/GO_0003367 cell-cell adhesion involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells. http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. http://purl.obolibrary.org/obo/GO_0003379 establishment of cell polarity involved in gastrulation cell migration http://purl.obolibrary.org/obo/GO_0003365 establishment of cell polarity involved in ameboidal cell migration The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/GO_0003380 establishment or maintenance of cytoskeleton polarity involved in gastrulation http://purl.obolibrary.org/obo/GO_0003371 establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. http://purl.obolibrary.org/obo/GO_0003381 epithelial cell morphogenesis involved in gastrulation http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. http://purl.obolibrary.org/obo/GO_0003382 epithelial cell morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0003403 optic vesicle formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/GO_0003404 optic vesicle morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. http://purl.obolibrary.org/obo/GO_0003407 neural retina development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0003411 cell motility involved in camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048870 cell motility Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye. http://purl.obolibrary.org/obo/GO_0003413 chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002062 chondrocyte differentiation The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0003414 chondrocyte morphogenesis involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized. http://purl.obolibrary.org/obo/GO_0003416 endochondral bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/GO_0003433 chondrocyte development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0002063 chondrocyte development The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity http://purl.obolibrary.org/obo/BFO_0000015 process A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a nucleic acid. http://purl.obolibrary.org/obo/GO_0003677 DNA binding http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0003682 chromatin binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0003723 RNA binding http://purl.obolibrary.org/obo/GO_0003676 nucleic acid binding Binding to an RNA molecule or a portion thereof. http://purl.obolibrary.org/obo/GO_0003824 catalytic activity http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. http://purl.obolibrary.org/obo/GO_0004553 hydrolase activity, hydrolyzing O-glycosyl compounds http://purl.obolibrary.org/obo/GO_0016798 hydrolase activity, acting on glycosyl bonds Catalysis of the hydrolysis of any O-glycosyl bond. http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. http://purl.obolibrary.org/obo/GO_0004896 cytokine receptor activity http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity http://purl.obolibrary.org/obo/GO_0004888 transmembrane signaling receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0004993 G protein-coupled serotonin receptor activity http://purl.obolibrary.org/obo/GO_0008227 G protein-coupled amine receptor activity Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. http://purl.obolibrary.org/obo/GO_0005126 cytokine receptor binding http://purl.obolibrary.org/obo/GO_0005102 signaling receptor binding Binding to a cytokine receptor. http://purl.obolibrary.org/obo/GO_0005488 binding http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0005515 protein binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a protein. http://purl.obolibrary.org/obo/GO_0005622 intracellular anatomical structure http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. http://purl.obolibrary.org/obo/GO_0005634 nucleus http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. http://purl.obolibrary.org/obo/GO_0005694 chromosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information. http://purl.obolibrary.org/obo/GO_0005737 cytoplasm http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. http://purl.obolibrary.org/obo/GO_0005739 mitochondrion http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. http://purl.obolibrary.org/obo/GO_0005741 mitochondrial outer membrane http://purl.obolibrary.org/obo/GO_0031968 organelle outer membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope. http://purl.obolibrary.org/obo/GO_0005764 lysosome http://purl.obolibrary.org/obo/GO_0000323 lytic vacuole A small lytic vacuole that has cell cycle-independent morphology found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions. http://purl.obolibrary.org/obo/GO_0005773 vacuole http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. http://purl.obolibrary.org/obo/GO_0005774 vacuolar membrane http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. http://purl.obolibrary.org/obo/GO_0005775 vacuolar lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed within the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0005829 cytosol http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. http://purl.obolibrary.org/obo/GO_0005840 ribosome http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins. http://purl.obolibrary.org/obo/GO_0005881 cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0005886 plasma membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. http://purl.obolibrary.org/obo/GO_0005976 polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0043170 macromolecule metabolic process The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides. http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one. http://purl.obolibrary.org/obo/GO_0006325 chromatin organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. http://purl.obolibrary.org/obo/GO_0006401 RNA catabolic process http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/GO_0006412 translation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome. http://purl.obolibrary.org/obo/GO_0006413 translational initiation http://purl.obolibrary.org/obo/GO_0008152 metabolic process The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/GO_0006414 translational elongation http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis. http://purl.obolibrary.org/obo/GO_0006415 translational termination http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code). http://purl.obolibrary.org/obo/GO_0006468 protein phosphorylation http://purl.obolibrary.org/obo/GO_0036211 protein modification process The process of introducing a phosphate group on to a protein. http://purl.obolibrary.org/obo/GO_0006508 proteolysis http://purl.obolibrary.org/obo/GO_0019538 protein metabolic process The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process http://purl.obolibrary.org/obo/GO_0044238 primary metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. http://purl.obolibrary.org/obo/GO_0006576 biogenic amine metabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0006581 acetylcholine catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/GO_0006606 protein import into nucleus http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. http://purl.obolibrary.org/obo/GO_0006837 serotonin transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. http://purl.obolibrary.org/obo/GO_0006839 mitochondrial transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport Transport of substances into, out of or within a mitochondrion. http://purl.obolibrary.org/obo/GO_0006865 amino acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0006869 lipid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. http://purl.obolibrary.org/obo/GO_0006909 phagocytosis http://purl.obolibrary.org/obo/GO_0006897 endocytosis A vesicle-mediated transport process that results in the engulfment of external particulate material by phagocytes and their delivery to the lysosome. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. http://purl.obolibrary.org/obo/GO_0006913 nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0051169 nuclear transport The directed movement of molecules between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/GO_0006914 autophagy http://purl.obolibrary.org/obo/GO_0061919 process utilizing autophagic mechanism The cellular catabolic process in which cells digest cellular materials, such as organelles and other macromolecular constituents, or non-self materials such as intracellular pathogens. Autophagy serves to provide essential nutrients under conditions of cellular stress; or can remodel intracellular structures during cell differentiation. http://purl.obolibrary.org/obo/GO_0006915 apoptotic process http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died. http://purl.obolibrary.org/obo/GO_0006925 inflammatory cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage. http://purl.obolibrary.org/obo/GO_0006940 regulation of smooth muscle contraction http://purl.obolibrary.org/obo/GO_0006937 regulation of muscle contraction Any process that modulates the frequency, rate or extent of smooth muscle contraction. http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction http://purl.obolibrary.org/obo/GO_0006936 muscle contraction A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. http://purl.obolibrary.org/obo/GO_0006949 syncytium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. http://purl.obolibrary.org/obo/GO_0006950 response to stress http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0006952 defense response http://purl.obolibrary.org/obo/GO_0006950 response to stress Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. http://purl.obolibrary.org/obo/GO_0006954 inflammatory response http://purl.obolibrary.org/obo/GO_0006952 defense response The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. http://purl.obolibrary.org/obo/GO_0006955 immune response http://purl.obolibrary.org/obo/GO_0002376 immune system process Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. http://purl.obolibrary.org/obo/GO_0006979 response to oxidative stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0006997 nucleus organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. http://purl.obolibrary.org/obo/GO_0007005 mitochondrion organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components. http://purl.obolibrary.org/obo/GO_0007009 plasma membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement http://purl.obolibrary.org/obo/GO_0007017 microtubule-based process A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0007033 vacuole organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0007040 lysosome organization http://purl.obolibrary.org/obo/GO_0080171 lytic vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases. http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The aggregation, arrangement and bonding together of a set of components to form a junction between cells. http://purl.obolibrary.org/obo/GO_0007049 cell cycle http://purl.obolibrary.org/obo/GO_0009987 cellular process The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. http://purl.obolibrary.org/obo/GO_0007097 nuclear migration http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the nucleus to a specific location within a cell. http://purl.obolibrary.org/obo/GO_0007127 meiosis I http://purl.obolibrary.org/obo/GO_0061982 meiosis I cell cycle process The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei. http://purl.obolibrary.org/obo/GO_0007154 cell communication http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0007155 cell adhesion http://purl.obolibrary.org/obo/GO_0009987 cellular process The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. http://purl.obolibrary.org/obo/GO_0007165 signal transduction http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by an extracellular ligand binding to a receptor located on the cell surface. The pathway ends with regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling http://purl.obolibrary.org/obo/GO_0023052 signaling Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0006836 neurotransmitter transport The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium-regulated exocytosis during synaptic transmission. http://purl.obolibrary.org/obo/GO_0007271 synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of acetylcholine from a presynapse, across a chemical synapse, the subsequent activation of dopamine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0007369 gastrulation http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. http://purl.obolibrary.org/obo/GO_0007389 pattern specification process http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0007398 ectoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. http://purl.obolibrary.org/obo/GO_0007405 neuroblast proliferation http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0007423 sensory organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0007492 endoderm development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. http://purl.obolibrary.org/obo/GO_0007507 heart development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. http://purl.obolibrary.org/obo/GO_0007519 skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. http://purl.obolibrary.org/obo/GO_0007585 respiratory gaseous exchange by respiratory system http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. http://purl.obolibrary.org/obo/GO_0007610 behavior http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction http://purl.obolibrary.org/obo/GO_1903522 regulation of blood circulation Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. http://purl.obolibrary.org/obo/GO_0008092 cytoskeletal protein binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). http://purl.obolibrary.org/obo/GO_0008134 transcription factor binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a transcription factor, a protein required to initiate or regulate transcription. http://purl.obolibrary.org/obo/GO_0008150 biological process http://purl.obolibrary.org/obo/BFO_0000015 process A biological process is the execution of a genetically-encoded biological module or program. It consists of all the steps required to achieve the specific biological objective of the module. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. http://purl.obolibrary.org/obo/GO_0008188 neuropeptide receptor activity http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity Combining with a neuropeptide to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0008217 regulation of blood pressure http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. http://purl.obolibrary.org/obo/GO_0008227 G protein-coupled amine receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation http://purl.obolibrary.org/obo/GO_0009987 cellular process The multiplication or reproduction of cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0008284 positive regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008289 lipid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a lipid. http://purl.obolibrary.org/obo/GO_0008528 G protein-coupled peptide receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0008585 female gonad development http://purl.obolibrary.org/obo/GO_0008406 gonad development The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0008652 amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism synthesizes chemical substances. This typically represents the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0009063 amino acid catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0009064 glutamine family amino acid metabolic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. http://purl.obolibrary.org/obo/GO_0009306 protein secretion http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region The controlled release of proteins from a cell. http://purl.obolibrary.org/obo/GO_0009536 plastid http://purl.obolibrary.org/obo/GO_0043231 intracellular membrane-bounded organelle Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. http://purl.obolibrary.org/obo/GO_0009547 plastid ribosome http://purl.obolibrary.org/obo/GO_0000313 organellar ribosome A ribosome contained within a plastid. http://purl.obolibrary.org/obo/GO_0009593 detection of chemical stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009605 response to external stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. http://purl.obolibrary.org/obo/GO_0009620 response to fungus http://purl.obolibrary.org/obo/GO_0051707 response to other organism Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. http://purl.obolibrary.org/obo/GO_0009755 hormone-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals mediated by the detection of a hormone. http://purl.obolibrary.org/obo/GO_0009791 post-embryonic development http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching http://purl.obolibrary.org/obo/GO_0009790 embryo development The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. http://purl.obolibrary.org/obo/GO_0009880 embryonic pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The process that results in the patterns of cell differentiation that will arise in an embryo. http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0009888 tissue development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0009913 epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. http://purl.obolibrary.org/obo/GO_0009914 hormone transport http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009967 positive regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009968 negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. http://purl.obolibrary.org/obo/GO_0009987 cellular process http://purl.obolibrary.org/obo/GO_0008150 biological process Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. http://purl.obolibrary.org/obo/GO_0010002 cardioblast differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0010467 gene expression http://purl.obolibrary.org/obo/GO_0009059 macromolecule biosynthetic process The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, as well as translation and maturation for protein-coding genes. http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010556 regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010558 negative regulation of macromolecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010604 positive regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010605 negative regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010668 ectodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The cellular component assembly that is part of the initial shaping of the component during its developmental progression. http://purl.obolibrary.org/obo/GO_0012501 programmed cell death http://purl.obolibrary.org/obo/GO_0008219 cell death A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell. http://purl.obolibrary.org/obo/GO_0014020 primary neural tube formation http://purl.obolibrary.org/obo/GO_0001838 embryonic epithelial tube formation The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development http://purl.obolibrary.org/obo/GO_0048864 stem cell development The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014075 response to amine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy http://purl.obolibrary.org/obo/GO_0003012 muscle system process The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/GO_0014897 striated muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014896 muscle hypertrophy The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group. http://purl.obolibrary.org/obo/GO_0015175 neutral L-amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of neutral L-amino acids from one side of a membrane to the other. Neutral amino acids have side chains with no charge at pH 7.3. http://purl.obolibrary.org/obo/GO_0015179 L-amino acid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015171 amino acid transmembrane transporter activity Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids. http://purl.obolibrary.org/obo/GO_0015464 acetylcholine receptor activity http://purl.obolibrary.org/obo/GO_0098960 postsynaptic neurotransmitter receptor activity Combining with an acetylcholine receptor ligand and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. http://purl.obolibrary.org/obo/GO_0015629 actin cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. http://purl.obolibrary.org/obo/GO_0015630 microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. http://purl.obolibrary.org/obo/GO_0015698 inorganic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015711 organic anion transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015804 neutral amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015813 L-glutamate transmembrane transport http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import The directed movement of L-glutamate across a membrane by means of some agent such as a transporter or a pore. http://purl.obolibrary.org/obo/GO_0015833 peptide transport http://purl.obolibrary.org/obo/GO_0042886 amide transport The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0016049 cell growth http://purl.obolibrary.org/obo/GO_0040007 growth The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. http://purl.obolibrary.org/obo/GO_0016050 vesicle organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. http://purl.obolibrary.org/obo/GO_0016051 carbohydrate biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0016052 carbohydrate catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process http://purl.obolibrary.org/obo/GO_0090304 nucleic acid metabolic process The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. http://purl.obolibrary.org/obo/GO_0016236 macroautophagy http://purl.obolibrary.org/obo/GO_0006914 autophagy The autophagic process that proceeds via the formation of an autophagosome. http://purl.obolibrary.org/obo/GO_0016301 kinase activity http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. http://purl.obolibrary.org/obo/GO_0016331 morphogenesis of embryonic epithelium http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structures of embryonic epithelia are generated and organized. http://purl.obolibrary.org/obo/GO_0016358 dendrite development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0016462 pyrophosphatase activity http://purl.obolibrary.org/obo/GO_0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Catalysis of the hydrolysis of a pyrophosphate bond (diphosphate bond) between two phosphate groups. http://purl.obolibrary.org/obo/GO_0016477 cell migration http://purl.obolibrary.org/obo/GO_0048870 cell motility The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. http://purl.obolibrary.org/obo/GO_0016740 transferase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/GO_0016755 aminoacyltransferase activity http://purl.obolibrary.org/obo/GO_0016746 acyltransferase activity Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor). http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. http://purl.obolibrary.org/obo/GO_0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides http://purl.obolibrary.org/obo/GO_0016817 hydrolase activity, acting on acid anhydrides Catalysis of the hydrolysis of any acid anhydride which contains phosphorus. http://purl.obolibrary.org/obo/GO_0016874 ligase activity http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalysis of the joining of two molecules, or two groups within a single molecule, using the energy from the hydrolysis of ATP, a similar triphosphate, or a pH gradient. http://purl.obolibrary.org/obo/GO_0016887 ATP hydrolysis activity http://purl.obolibrary.org/obo/GO_0017111 ribonucleoside triphosphate phosphatase activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. http://purl.obolibrary.org/obo/GO_0017111 ribonucleoside triphosphate phosphatase activity http://purl.obolibrary.org/obo/GO_0016462 pyrophosphatase activity Catalysis of the reaction: a ribonucleoside triphosphate + H2O = a ribonucleoside diphosphate + H+ + phosphate. http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0019221 cytokine-mediated signaling pathway http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with the regulation of a downstream cellular process, e.g. transcription. http://purl.obolibrary.org/obo/GO_0019778 Atg12 activating enzyme activity http://purl.obolibrary.org/obo/GO_0008641 ubiquitin-like modifier activating enzyme activity Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond. http://purl.obolibrary.org/obo/GO_0019786 protein-phosphatidylethanolamide deconjugating activity http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of the reaction: [protein]-C-terminal L-amino acid-glycyl-phosphatidylethanolamide + H2O = [protein]-C-terminal L-amino acid-glycine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine. An example of this reaction is the removal of ATG8 from membranes to which it is covalently linked to a phosphatidylethanolamid via its terminal glycine residue. http://purl.obolibrary.org/obo/GO_0019882 antigen processing and presentation http://purl.obolibrary.org/obo/GO_0002376 immune system process The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. http://purl.obolibrary.org/obo/GO_0019953 sexual reproduction http://purl.obolibrary.org/obo/GO_0022414 reproductive process A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). http://purl.obolibrary.org/obo/GO_0019954 asexual reproduction http://purl.obolibrary.org/obo/GO_0022414 reproductive process A type of reproduction in which new individuals are produced from a single organism, either from an unfertilized egg or from a single cell or group of cells. http://purl.obolibrary.org/obo/GO_0019955 cytokine binding http://purl.obolibrary.org/obo/GO_0005515 protein binding Binding to a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity. http://purl.obolibrary.org/obo/GO_0021915 neural tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. http://purl.obolibrary.org/obo/GO_0022402 cell cycle process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase http://purl.obolibrary.org/obo/GO_0044848 biological phase One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. http://purl.obolibrary.org/obo/GO_0022412 cellular process involved in reproduction in multicellular organism http://purl.obolibrary.org/obo/GO_0009987 cellular process A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. http://purl.obolibrary.org/obo/GO_0022414 reproductive process http://purl.obolibrary.org/obo/GO_0008150 biological process A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. http://purl.obolibrary.org/obo/GO_0022600 digestive system process http://purl.obolibrary.org/obo/GO_0003008 system process A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The aggregation, arrangement and bonding together of a cellular component. http://purl.obolibrary.org/obo/GO_0022618 protein-RNA complex assembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0023051 regulation of signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023056 positive regulation of signaling http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0023057 negative regulation of signaling http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity The specification and formation of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. http://purl.obolibrary.org/obo/GO_0030098 lymphocyte differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. http://purl.obolibrary.org/obo/GO_0030103 vasopressin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of vasopressin from secretory granules into the blood. http://purl.obolibrary.org/obo/GO_0030141 secretory granule http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules. http://purl.obolibrary.org/obo/GO_0030154 cell differentiation http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron. http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process http://purl.obolibrary.org/obo/GO_0006022 aminoglycan metabolic process The chemical reactions and pathways involving glycosaminoglycans, any of a group of linear polysaccharides composed of repeating disaccharide units. http://purl.obolibrary.org/obo/GO_0030217 T cell differentiation http://purl.obolibrary.org/obo/GO_0042110 T cell activation The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/GO_0030247 polysaccharide binding http://purl.obolibrary.org/obo/GO_0030246 carbohydrate binding Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation http://purl.obolibrary.org/obo/GO_0051276 chromosome organization The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030335 positive regulation of cell migration http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility Any process that activates or increases the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030336 negative regulation of cell migration http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. http://purl.obolibrary.org/obo/GO_0030428 cell septum http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells. http://purl.obolibrary.org/obo/GO_0030447 filamentous growth http://purl.obolibrary.org/obo/GO_0040007 growth The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. http://purl.obolibrary.org/obo/GO_0030473 nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a leukocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a secretory granule. http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. http://purl.obolibrary.org/obo/GO_0030857 negative regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0007010 cytoskeleton organization Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0031128 developmental induction http://purl.obolibrary.org/obo/GO_0032502 developmental process A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). http://purl.obolibrary.org/obo/GO_0031175 neuron projection development http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0031252 cell leading edge http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The area of a motile cell closest to the direction of movement. http://purl.obolibrary.org/obo/GO_0031333 negative regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031334 positive regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0031348 negative regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031349 positive regulation of defense response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that activates or increases the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031399 regulation of protein modification process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. http://purl.obolibrary.org/obo/GO_0031400 negative regulation of protein modification process http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. http://purl.obolibrary.org/obo/GO_0031401 positive regulation of protein modification process http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle A vesicle found in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0031981 nuclear lumen http://purl.obolibrary.org/obo/GO_0070013 intracellular organelle lumen The volume enclosed by the nuclear inner membrane. http://purl.obolibrary.org/obo/GO_0032091 negative regulation of protein binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0032101 regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032103 positive regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032432 actin filament bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process http://purl.obolibrary.org/obo/GO_0008150 biological process Any biological process, occurring at the level of a multicellular organism, pertinent to its function. http://purl.obolibrary.org/obo/GO_0032502 developmental process http://purl.obolibrary.org/obo/GO_0008150 biological process A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0032774 RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0016070 RNA metabolic process The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication. http://purl.obolibrary.org/obo/GO_0032940 secretion by cell http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a cell. http://purl.obolibrary.org/obo/GO_0032984 protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization The disaggregation of a protein-containing macromolecular complex into its constituent components. http://purl.obolibrary.org/obo/GO_0032988 protein-RNA complex disassembly http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization The disaggregation of a protein-RNA complex into its constituent components. http://purl.obolibrary.org/obo/GO_0032989 cellular anatomical entity morphogenesis http://purl.obolibrary.org/obo/GO_0016043 cellular component organization The process in which a cellular entity is generated and organized. A cellular entity has granularity above the level of a protein complex but below that of an anatomical system. http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex http://purl.obolibrary.org/obo/GO_0005575 cellular_component A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage. http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0033293 monocarboxylic acid binding http://purl.obolibrary.org/obo/GO_0031406 carboxylic acid binding Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-). http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization http://purl.obolibrary.org/obo/GO_0016050 vesicle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0033554 cellular response to stress http://purl.obolibrary.org/obo/GO_0006950 response to stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0034248 regulation of amide metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034249 negative regulation of amide metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034250 positive regulation of amide metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. http://purl.obolibrary.org/obo/GO_0034599 cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_0062197 cellular response to chemical stress Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0035050 embryonic heart tube development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/GO_0035282 segmentation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. http://purl.obolibrary.org/obo/GO_0035556 intracellular signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. http://purl.obolibrary.org/obo/GO_0035987 endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. http://purl.obolibrary.org/obo/GO_0035989 tendon development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. http://purl.obolibrary.org/obo/GO_0036072 direct ossification http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. http://purl.obolibrary.org/obo/GO_0036093 germ cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0036094 small molecule binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0036293 response to decreased oxygen levels http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. http://purl.obolibrary.org/obo/GO_0036336 dendritic cell migration http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration The movement of a dendritic cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity http://purl.obolibrary.org/obo/GO_0060089 molecular transducer activity Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. http://purl.obolibrary.org/obo/GO_0040007 growth http://purl.obolibrary.org/obo/GO_0008150 biological process The increase in size or mass of an entire organism, a part of an organism or a cell. http://purl.obolibrary.org/obo/GO_0040008 regulation of growth http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. http://purl.obolibrary.org/obo/GO_0042074 cell migration involved in gastrulation http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). http://purl.obolibrary.org/obo/GO_0042098 T cell proliferation http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation The expansion of a T cell population by cell division. Follows T cell activation. http://purl.obolibrary.org/obo/GO_0042110 T cell activation http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. http://purl.obolibrary.org/obo/GO_0042116 macrophage activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042117 monocyte activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042118 endothelial cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0042221 response to chemical http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0042254 ribosome biogenesis http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. http://purl.obolibrary.org/obo/GO_0042255 ribosome assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly The aggregation, arrangement and bonding together of the mature ribosome and of its subunits. http://purl.obolibrary.org/obo/GO_0042277 peptide binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. http://purl.obolibrary.org/obo/GO_0042325 regulation of phosphorylation http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. http://purl.obolibrary.org/obo/GO_0042326 negative regulation of phosphorylation http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. http://purl.obolibrary.org/obo/GO_0042327 positive regulation of phosphorylation http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. http://purl.obolibrary.org/obo/GO_0042330 taxis http://purl.obolibrary.org/obo/GO_0040011 locomotion The directed movement of a motile cell or organism in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. http://purl.obolibrary.org/obo/GO_0042401 biogenic amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0042402 biogenic amine catabolic process http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. http://purl.obolibrary.org/obo/GO_0042592 homeostatic process http://purl.obolibrary.org/obo/GO_0008150 biological process Any biological process involved in the maintenance of an internal steady state. http://purl.obolibrary.org/obo/GO_0042641 actomyosin http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Any complex of actin, myosin, and accessory proteins. http://purl.obolibrary.org/obo/GO_0042645 mitochondrial nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a mitochondrion to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that modulates the occurrence or rate of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0042995 cell projection http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0043009 chordate embryonic development http://purl.obolibrary.org/obo/GO_0009792 embryo development ending in birth or egg hatching The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. http://purl.obolibrary.org/obo/GO_0043010 camera-type eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/GO_0043011 myeloid dendritic cell differentiation http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. http://purl.obolibrary.org/obo/GO_0043029 T cell homeostasis http://purl.obolibrary.org/obo/GO_0002260 lymphocyte homeostasis The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0043043 peptide biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. http://purl.obolibrary.org/obo/GO_0043073 germ cell nucleus http://purl.obolibrary.org/obo/GO_0005634 nucleus The nucleus of a germ cell, a reproductive cell in multicellular organisms. http://purl.obolibrary.org/obo/GO_0043083 synaptic cleft http://purl.obolibrary.org/obo/GO_0005576 extracellular region The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released. http://purl.obolibrary.org/obo/GO_0043168 anion binding http://purl.obolibrary.org/obo/GO_0043167 ion binding Binding to an anion, a charged atom or group of atoms with a net negative charge. http://purl.obolibrary.org/obo/GO_0043171 peptide catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. http://purl.obolibrary.org/obo/GO_0043207 response to external biotic stimulus http://purl.obolibrary.org/obo/GO_0009607 response to biotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. http://purl.obolibrary.org/obo/GO_0043226 organelle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043232 intracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043235 receptor complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of protein complex assembly. http://purl.obolibrary.org/obo/GO_0043436 oxoacid metabolic process http://purl.obolibrary.org/obo/GO_0006082 organic acid metabolic process The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation http://purl.obolibrary.org/obo/GO_0003012 muscle system process A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0043534 blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. http://purl.obolibrary.org/obo/GO_0043603 amide metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. http://purl.obolibrary.org/obo/GO_0043604 amide biosynthetic process http://purl.obolibrary.org/obo/GO_0043603 amide metabolic process The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/GO_0043605 amide catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. http://purl.obolibrary.org/obo/GO_0043936 asexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0030436 asexual sporulation The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/GO_0044065 regulation of respiratory system process http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. http://purl.obolibrary.org/obo/GO_0044703 multi-organism reproductive process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A biological process that directly contributes to the process of producing new individuals, involving another organism. http://purl.obolibrary.org/obo/GO_0044848 biological phase http://purl.obolibrary.org/obo/GO_0008150 biological process A distinct period or stage in a biological process or cycle. http://purl.obolibrary.org/obo/GO_0045026 plasma membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. http://purl.obolibrary.org/obo/GO_0045087 innate immune response http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. http://purl.obolibrary.org/obo/GO_0045088 regulation of innate immune response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. http://purl.obolibrary.org/obo/GO_0045089 positive regulation of innate immune response http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection. http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process by which a cell establishes the intrinsic character of a cell or tissue region irreversibly committing it to a particular fate. http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation http://purl.obolibrary.org/obo/GO_0002376 immune system process A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045638 negative regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045639 positive regulation of myeloid cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. http://purl.obolibrary.org/obo/GO_0045730 respiratory burst http://purl.obolibrary.org/obo/GO_0008152 metabolic process A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0045744 negative regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0045822 negative regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/GO_0045823 positive regulation of heart contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that activates or increases the frequency, rate or extent of heart contraction. http://purl.obolibrary.org/obo/GO_0045824 negative regulation of innate immune response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response. http://purl.obolibrary.org/obo/GO_0045839 negative regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother. http://purl.obolibrary.org/obo/GO_0045920 negative regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0045921 positive regulation of exocytosis http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell Any process that activates or increases the frequency, rate or extent of exocytosis. http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0046165 alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom. http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0046530 photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046620 regulation of organ growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046649 lymphocyte activation http://purl.obolibrary.org/obo/GO_0045321 leukocyte activation A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0046651 lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation The expansion of a lymphocyte population by cell division. http://purl.obolibrary.org/obo/GO_0046717 acid secretion http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of acid by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0046879 hormone secretion http://purl.obolibrary.org/obo/GO_0023061 signal release The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. http://purl.obolibrary.org/obo/GO_0046903 secretion http://purl.obolibrary.org/obo/GO_0006810 transport The controlled release of a substance by a cell or a tissue. http://purl.obolibrary.org/obo/GO_0046928 regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell. http://purl.obolibrary.org/obo/GO_0048143 astrocyte activation http://purl.obolibrary.org/obo/GO_0061900 glial cell activation A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0048209 regulation of vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0048247 lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The directed movement of a lymphocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0048284 organelle fusion http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of a single organelle from two or more organelles. http://purl.obolibrary.org/obo/GO_0048285 organelle fission http://purl.obolibrary.org/obo/GO_0006996 organelle organization The creation of two or more organelles by division of one organelle. http://purl.obolibrary.org/obo/GO_0048308 organelle inheritance http://purl.obolibrary.org/obo/GO_0006996 organelle organization The partitioning of organelles between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0048311 mitochondrion distribution http://purl.obolibrary.org/obo/GO_0051646 mitochondrion localization Any process that establishes the spatial arrangement of mitochondria between and within cells. http://purl.obolibrary.org/obo/GO_0048332 mesoderm morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of the mesoderm are generated and organized. http://purl.obolibrary.org/obo/GO_0048333 mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. http://purl.obolibrary.org/obo/GO_0048368 lateral mesoderm development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048468 cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The cellular developmental process in which a specific cell progresses from an immature to a mature state. Cell development start once cell commitment has taken place. http://purl.obolibrary.org/obo/GO_0048469 cell maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation The cellular developmental process, independent of morphogenetic (shape) change, that is required for a specific cell to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0048505 regulation of timing of cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development. http://purl.obolibrary.org/obo/GO_0048513 animal organ development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0035239 tube morphogenesis The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048584 positive regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. http://purl.obolibrary.org/obo/GO_0048589 developmental growth http://purl.obolibrary.org/obo/GO_0040007 growth The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the eye are generated and organized. http://purl.obolibrary.org/obo/GO_0048593 camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048592 eye morphogenesis The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. http://purl.obolibrary.org/obo/GO_0048596 embryonic camera-type eye morphogenesis http://purl.obolibrary.org/obo/GO_0048048 embryonic eye morphogenesis The process in which the anatomical structures of the eye are generated and organized during embryonic development. http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. http://purl.obolibrary.org/obo/GO_0048599 oocyte development http://purl.obolibrary.org/obo/GO_0007281 germ cell development The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048608 reproductive structure development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. http://purl.obolibrary.org/obo/GO_0048645 animal organ formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis http://purl.obolibrary.org/obo/GO_0032502 developmental process The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048666 neuron development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. http://purl.obolibrary.org/obo/GO_0048699 generation of neurons http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. http://purl.obolibrary.org/obo/GO_0048705 skeletal system morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skeleton are generated and organized. http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of a tissue are generated and organized. http://purl.obolibrary.org/obo/GO_0048731 system development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. http://purl.obolibrary.org/obo/GO_0048732 gland development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. http://purl.obolibrary.org/obo/GO_0048738 cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0014706 striated muscle tissue development The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048749 compound eye development http://purl.obolibrary.org/obo/GO_0001654 eye development The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube http://purl.obolibrary.org/obo/GO_0061138 morphogenesis of a branching epithelium The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling. http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development http://purl.obolibrary.org/obo/GO_0032502 developmental process The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0048858 cell projection morphogenesis http://purl.obolibrary.org/obo/GO_0030030 cell projection organization The process in which the anatomical structures of a cell projection are generated and organized. http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process http://purl.obolibrary.org/obo/GO_0032502 developmental process A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. http://purl.obolibrary.org/obo/GO_0048870 cell motility http://purl.obolibrary.org/obo/GO_0009987 cellular process Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis http://purl.obolibrary.org/obo/GO_0042592 homeostatic process Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050679 positive regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that activates or increases the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050680 negative regulation of epithelial cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response http://purl.obolibrary.org/obo/GO_0050727 regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of the inflammatory response. http://purl.obolibrary.org/obo/GO_0050769 positive regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050777 negative regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050778 positive regulation of immune response http://purl.obolibrary.org/obo/GO_0050776 regulation of immune response Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0050806 positive regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/GO_0050808 synapse organization http://purl.obolibrary.org/obo/GO_0034330 cell junction organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0050866 negative regulation of cell activation http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. http://purl.obolibrary.org/obo/GO_0050867 positive regulation of cell activation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of activation. http://purl.obolibrary.org/obo/GO_0050877 nervous system process http://purl.obolibrary.org/obo/GO_0003008 system process An organ system process carried out by any of the organs or tissues of the neurological system. http://purl.obolibrary.org/obo/GO_0050878 regulation of body fluid levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that modulates the levels of body fluids. http://purl.obolibrary.org/obo/GO_0050881 musculoskeletal movement http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. http://purl.obolibrary.org/obo/GO_0050886 endocrine process http://purl.obolibrary.org/obo/GO_0003008 system process The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The movement of a leukocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0050905 neuromuscular process http://purl.obolibrary.org/obo/GO_0050877 nervous system process Any process pertaining to the functions of the nervous and muscular systems of an organism. http://purl.obolibrary.org/obo/GO_0050912 detection of chemical stimulus involved in sensory perception of taste http://purl.obolibrary.org/obo/GO_0050907 detection of chemical stimulus involved in sensory perception The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0050920 regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/GO_0050921 positive regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/GO_0050922 negative regulation of chemotaxis http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient. http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051047 positive regulation of secretion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051048 negative regulation of secretion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051093 negative regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051094 positive regulation of developmental process http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051216 cartilage development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051254 positive regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051258 protein polymerization http://purl.obolibrary.org/obo/GO_0065003 protein-containing complex assembly The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. http://purl.obolibrary.org/obo/GO_0051276 chromosome organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome. http://purl.obolibrary.org/obo/GO_0051301 cell division http://purl.obolibrary.org/obo/GO_0009987 cellular process The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. http://purl.obolibrary.org/obo/GO_0051321 meiotic cell cycle http://purl.obolibrary.org/obo/GO_0022414 reproductive process Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. http://purl.obolibrary.org/obo/GO_0051326 telophase http://purl.obolibrary.org/obo/GO_0022403 cell cycle phase The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts. http://purl.obolibrary.org/obo/GO_0051493 regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051590 positive regulation of neurotransmitter transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051707 response to other organism http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. http://purl.obolibrary.org/obo/GO_0051726 regulation of cell cycle http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0051955 regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051956 negative regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051957 positive regulation of amino acid transport http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the anatomical structures of cardiac muscle tissue are generated and organized. http://purl.obolibrary.org/obo/GO_0055010 ventricular cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. http://purl.obolibrary.org/obo/GO_0055017 cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. http://purl.obolibrary.org/obo/GO_0060039 pericardium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. http://purl.obolibrary.org/obo/GO_0060041 retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. http://purl.obolibrary.org/obo/GO_0060231 mesenchymal to epithelial transition http://purl.obolibrary.org/obo/GO_0030855 epithelial cell differentiation A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. http://purl.obolibrary.org/obo/GO_0060249 anatomical structure homeostasis http://purl.obolibrary.org/obo/GO_0048871 multicellular organismal-level homeostasis A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. http://purl.obolibrary.org/obo/GO_0060350 endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. http://purl.obolibrary.org/obo/GO_0060351 cartilage development involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. http://purl.obolibrary.org/obo/GO_0060379 cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. http://purl.obolibrary.org/obo/GO_0060412 ventricular septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. http://purl.obolibrary.org/obo/GO_0060413 atrial septum morphogenesis http://purl.obolibrary.org/obo/GO_0060411 cardiac septum morphogenesis The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. http://purl.obolibrary.org/obo/GO_0060419 heart growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060429 epithelium development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of cartilage are generated and organized. http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development http://purl.obolibrary.org/obo/GO_0007517 muscle organ development The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. http://purl.obolibrary.org/obo/GO_0060560 developmental growth involved in morphogenesis http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development Any apoptotic process that contributes to the shaping of an anatomical structure. http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0002065 columnar/cuboidal epithelial cell differentiation The process in which epiblast cells acquire specialized features of neuroepithelial cells. http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The morphogenetic process in which an epithelial sheet bends along a linear axis. http://purl.obolibrary.org/obo/GO_0060632 regulation of microtubule-based movement http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060760 positive regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that increases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060761 negative regulation of response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0060759 regulation of response to cytokine stimulus Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus. http://purl.obolibrary.org/obo/GO_0060788 ectodermal placode formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0060795 cell fate commitment involved in formation of primary germ layer http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. http://purl.obolibrary.org/obo/GO_0060841 venous blood vessel development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. http://purl.obolibrary.org/obo/GO_0060900 embryonic camera-type eye formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. http://purl.obolibrary.org/obo/GO_0060914 heart formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. http://purl.obolibrary.org/obo/GO_0060932 His-Purkinje system cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. http://purl.obolibrary.org/obo/GO_0060974 cell migration involved in heart formation http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. http://purl.obolibrary.org/obo/GO_0060976 coronary vasculature development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0060977 coronary vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. http://purl.obolibrary.org/obo/GO_0061025 membrane fusion http://purl.obolibrary.org/obo/GO_0061024 membrane organization The membrane organization process that joins two lipid bilayers to form a single membrane. http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061049 cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061053 somite development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. http://purl.obolibrary.org/obo/GO_0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response http://purl.obolibrary.org/obo/GO_0002720 positive regulation of cytokine production involved in immune response Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response. http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production http://purl.obolibrary.org/obo/GO_0002367 cytokine production involved in immune response Any process that contributes to cytokine production by a myeloid cell. http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development http://purl.obolibrary.org/obo/GO_0014032 neural crest cell development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. http://purl.obolibrary.org/obo/GO_0061309 cardiac neural crest cell development involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061308 cardiac neural crest cell development involved in heart development The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/GO_0061311 cell surface receptor signaling pathway involved in heart development http://purl.obolibrary.org/obo/GO_0007166 cell surface receptor signaling pathway The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time. http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061343 cell adhesion involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0007155 cell adhesion The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061448 connective tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of a connective tissue over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061651 Atg12 conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0061650 ubiquitin-like protein conjugating enzyme activity Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y = Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue. http://purl.obolibrary.org/obo/GO_0061660 Atg12 ligase activity http://purl.obolibrary.org/obo/GO_0061659 ubiquitin-like protein ligase activity Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S = X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate. http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. http://purl.obolibrary.org/obo/GO_0070227 lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070229 negative regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070230 positive regulation of lymphocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070278 extracellular matrix constituent secretion http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. http://purl.obolibrary.org/obo/GO_0070482 response to oxygen levels http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. http://purl.obolibrary.org/obo/GO_0070483 detection of hypoxia http://purl.obolibrary.org/obo/GO_0003032 detection of oxygen The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. http://purl.obolibrary.org/obo/GO_0070586 cell-cell adhesion involved in gastrulation http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one cell to another cell affecting gastrulation. http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a leukocyte population by cell division. http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. http://purl.obolibrary.org/obo/GO_0070925 organelle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0071554 cell wall organization or biogenesis http://purl.obolibrary.org/obo/GO_0009987 cellular process A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall. http://purl.obolibrary.org/obo/GO_0071621 granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration The movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071674 mononuclear cell migration http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation http://purl.obolibrary.org/obo/GO_0021700 developmental maturation A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0071709 membrane assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a membrane. http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. http://purl.obolibrary.org/obo/GO_0071897 DNA biosynthetic process http://purl.obolibrary.org/obo/GO_0006259 DNA metabolic process The biosynthetic process resulting in the formation of DNA. http://purl.obolibrary.org/obo/GO_0072132 mesenchyme morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation http://purl.obolibrary.org/obo/GO_0035148 tube formation The developmental process pertaining to the initial formation of an epithelial tube. http://purl.obolibrary.org/obo/GO_0072330 monocarboxylic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0046394 carboxylic acid biosynthetic process The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. http://purl.obolibrary.org/obo/GO_0080135 regulation of cellular response to stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0090087 regulation of peptide transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0090171 chondrocyte morphogenesis http://purl.obolibrary.org/obo/GO_0000902 cell morphogenesis The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion http://purl.obolibrary.org/obo/GO_0061025 membrane fusion The joining of two lipid bilayers to form a single organelle membrane. http://purl.obolibrary.org/obo/GO_0097028 dendritic cell differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/GO_0097164 ammonium ion metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving the ammonium ion. http://purl.obolibrary.org/obo/GO_0097190 apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0007165 signal transduction The series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered. http://purl.obolibrary.org/obo/GO_0097367 carbohydrate derivative binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a carbohydrate derivative. http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration http://purl.obolibrary.org/obo/GO_0050900 leukocyte migration The movement of a myeloid leukocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism http://purl.obolibrary.org/obo/GO_0051707 response to other organism Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. http://purl.obolibrary.org/obo/GO_0098588 bounding membrane of organelle http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer that forms the outer-most layer of an organelle. http://purl.obolibrary.org/obo/GO_0098657 import into cell http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/GO_0098764 meiosis I cell cycle phase http://purl.obolibrary.org/obo/GO_0098762 meiotic cell cycle phase A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs. http://purl.obolibrary.org/obo/GO_0098773 skin epidermis development http://purl.obolibrary.org/obo/GO_0008544 epidermis development The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is part of a membrane. http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098799 outer mitochondrial membrane protein complex http://purl.obolibrary.org/obo/GO_0098796 membrane protein complex Any protein complex that is part of the outer mitochondrial membrane. http://purl.obolibrary.org/obo/GO_0098813 nuclear chromosome segregation http://purl.obolibrary.org/obo/GO_0007059 chromosome segregation The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles. http://purl.obolibrary.org/obo/GO_0098852 lytic vacuole membrane http://purl.obolibrary.org/obo/GO_0005774 vacuolar membrane The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell. http://purl.obolibrary.org/obo/GO_0098868 bone growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a bone that contributes to the shaping of that bone. http://purl.obolibrary.org/obo/GO_0098988 G protein-coupled glutamate receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. http://purl.obolibrary.org/obo/GO_0099513 polymeric cytoskeletal fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. http://purl.obolibrary.org/obo/GO_0099612 protein localization to axon http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to or maintained in a location within an axon. http://purl.obolibrary.org/obo/GO_1900150 regulation of defense response to fungus http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to fungus. http://purl.obolibrary.org/obo/GO_1901363 heterocyclic compound binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to heterocyclic compound. http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901607 alpha-amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways resulting in the formation of an alpha-amino acid. http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902106 negative regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902107 positive regulation of leukocyte differentiation http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. http://purl.obolibrary.org/obo/GO_1902275 regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1902369 negative regulation of RNA catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process. http://purl.obolibrary.org/obo/GO_1902494 catalytic complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex which is capable of catalytic activity. http://purl.obolibrary.org/obo/GO_1902692 regulation of neuroblast proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of neuroblast proliferation. http://purl.obolibrary.org/obo/GO_1902742 apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process that is involved in anatomical structure development. http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process http://purl.obolibrary.org/obo/GO_0022414 reproductive process A process that is part of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_1903047 mitotic cell cycle process http://purl.obolibrary.org/obo/GO_0022402 cell cycle process A process that is part of the mitotic cell cycle. http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903054 negative regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903055 positive regulation of extracellular matrix organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. http://purl.obolibrary.org/obo/GO_1903409 reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_0072593 reactive oxygen species metabolic process The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0051046 regulation of secretion Any process that modulates the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell http://purl.obolibrary.org/obo/GO_1903530 regulation of secretion by cell Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1903532 positive regulation of secretion by cell http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of secretion by cell. http://purl.obolibrary.org/obo/GO_1904746 negative regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904747 positive regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of apoptotic process involved in development. http://purl.obolibrary.org/obo/GO_1905037 autophagosome organization http://purl.obolibrary.org/obo/GO_0007033 vacuole organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome. http://purl.obolibrary.org/obo/GO_1905039 carboxylic acid transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which carboxylic acid is transported across a membrane. http://purl.obolibrary.org/obo/GO_1905145 cellular response to acetylcholine http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus. http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905331 negative regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1990234 transferase complex http://purl.obolibrary.org/obo/GO_1902494 catalytic complex A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of multicellular organismal development. http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of animal organ morphogenesis. http://purl.obolibrary.org/obo/GO_2000114 regulation of establishment of cell polarity http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity Any process that modulates the frequency, rate or extent of establishment of cell polarity. http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000137 negative regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000138 positive regulation of cell proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. http://purl.obolibrary.org/obo/GO_2000179 positive regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000648 positive regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that activates or increases the frequency, rate or extent of stem cell proliferation. http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis http://purl.obolibrary.org/obo/GO_2000027 regulation of animal organ morphogenesis Any process that modulates the frequency, rate or extent of heart morphogenesis. http://purl.obolibrary.org/obo/GO_2001141 regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_0018995 host cellular component http://purl.obolibrary.org/obo/GO_0044217 other organism part Any cellular component of a host cell. The host is an organism in which another organism, for instance a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection. http://purl.obolibrary.org/obo/GO_0019093 mitochondrial RNA localization http://purl.obolibrary.org/obo/GO_0006403 RNA localization Any process in which mitochondrial RNA is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. http://purl.obolibrary.org/obo/GO_0019226 transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0050877 nervous system process The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission. http://purl.obolibrary.org/obo/GO_0019228 neuronal action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a neuron. http://purl.obolibrary.org/obo/GO_0019233 sensory perception of pain http://purl.obolibrary.org/obo/GO_0007600 sensory perception The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. A painful stimulus is any physical or chemical event that has the potential to cause tissue damage (actual or perceived) and activates the nociceptive system. http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0019336 phenol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/GO_0019777 Atg12 transferase activity http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y = Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages. http://purl.obolibrary.org/obo/GO_0019825 oxygen binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to oxygen (O2). http://purl.obolibrary.org/obo/GO_0019835 cytolysis http://purl.obolibrary.org/obo/GO_0009987 cellular process The rupture of cell membranes and the loss of cytoplasm. http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0047497 mitochondrion transport along microtubule The directed movement of mitochondria along microtubules in nerve cell axons. http://purl.obolibrary.org/obo/GO_0021501 prechordal plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. http://purl.obolibrary.org/obo/GO_0021508 floor plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage. http://purl.obolibrary.org/obo/GO_0021510 spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. http://purl.obolibrary.org/obo/GO_0021514 ventral spinal cord interneuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021515 cell differentiation in spinal cord http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021517 ventral spinal cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021523 somatic motor neuron differentiation http://purl.obolibrary.org/obo/GO_0021522 spinal cord motor neuron differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021531 spinal cord radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021532 neural tube patterning http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. http://purl.obolibrary.org/obo/GO_0021533 cell differentiation in hindbrain http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021534 cell proliferation in hindbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell that will reside in the hindbrain. http://purl.obolibrary.org/obo/GO_0021536 diencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021537 telencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. http://purl.obolibrary.org/obo/GO_0021538 epithalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. http://purl.obolibrary.org/obo/GO_0021543 pallium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. http://purl.obolibrary.org/obo/GO_0021544 subpallium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development http://purl.obolibrary.org/obo/GO_0021675 nerve development The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021546 rhombomere development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021547 midbrain-hindbrain boundary initiation http://purl.obolibrary.org/obo/GO_0003002 regionalization The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021548 pons development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021549 cerebellum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021550 medulla oblongata development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021551 central nervous system morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021555 midbrain-hindbrain boundary morphogenesis http://purl.obolibrary.org/obo/GO_0048598 embryonic morphogenesis The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021556 central nervous system formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021559 trigeminal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021563 glossopharyngeal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021564 vagus nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021565 accessory nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021566 hypoglossal nerve development http://purl.obolibrary.org/obo/GO_0021545 cranial nerve development The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021567 rhombomere 1 development http://purl.obolibrary.org/obo/GO_0021546 rhombomere development The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021575 hindbrain morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021576 hindbrain formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021578 hindbrain maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. http://purl.obolibrary.org/obo/GO_0021579 medulla oblongata morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021580 medulla oblongata formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021582 medulla oblongata maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. http://purl.obolibrary.org/obo/GO_0021583 pons morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021584 pons formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021586 pons maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. http://purl.obolibrary.org/obo/GO_0021587 cerebellum morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021588 cerebellum formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021590 cerebellum maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. http://purl.obolibrary.org/obo/GO_0021591 ventricular system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. http://purl.obolibrary.org/obo/GO_0021592 fourth ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space. http://purl.obolibrary.org/obo/GO_0021593 rhombomere morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021594 rhombomere formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation http://purl.obolibrary.org/obo/GO_0021682 nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. http://purl.obolibrary.org/obo/GO_0021606 accessory nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021607 accessory nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021608 accessory nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. http://purl.obolibrary.org/obo/GO_0021614 glossopharyngeal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021615 glossopharyngeal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021616 glossopharyngeal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. http://purl.obolibrary.org/obo/GO_0021618 hypoglossal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021619 hypoglossal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021620 hypoglossal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. http://purl.obolibrary.org/obo/GO_0021626 central nervous system maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. http://purl.obolibrary.org/obo/GO_0021635 trigeminal nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021636 trigeminal nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021638 trigeminal nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. http://purl.obolibrary.org/obo/GO_0021643 vagus nerve maturation http://purl.obolibrary.org/obo/GO_0021605 cranial nerve maturation A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021644 vagus nerve morphogenesis http://purl.obolibrary.org/obo/GO_0021602 cranial nerve morphogenesis The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021646 vagus nerve formation http://purl.obolibrary.org/obo/GO_0021603 cranial nerve formation The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. http://purl.obolibrary.org/obo/GO_0021651 rhombomere 1 morphogenesis http://purl.obolibrary.org/obo/GO_0021593 rhombomere morphogenesis The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021652 rhombomere 1 formation http://purl.obolibrary.org/obo/GO_0021594 rhombomere formation The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021654 rhombomere boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. http://purl.obolibrary.org/obo/GO_0021670 lateral ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. http://purl.obolibrary.org/obo/GO_0021675 nerve development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021678 third ventricle development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina. http://purl.obolibrary.org/obo/GO_0021679 cerebellar molecular layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021680 cerebellar Purkinje cell layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021681 cerebellar granular layer development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021682 nerve maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0021683 cerebellar granular layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021684 cerebellar granular layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021686 cerebellar granular layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. http://purl.obolibrary.org/obo/GO_0021687 cerebellar molecular layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021688 cerebellar molecular layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021690 cerebellar molecular layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. http://purl.obolibrary.org/obo/GO_0021691 cerebellar Purkinje cell layer maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021692 cerebellar Purkinje cell layer morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021694 cerebellar Purkinje cell layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. http://purl.obolibrary.org/obo/GO_0021695 cerebellar cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021696 cerebellar cortex morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021697 cerebellar cortex formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021699 cerebellar cortex maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. http://purl.obolibrary.org/obo/GO_0021701 cerebellar Golgi cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021702 cerebellar Purkinje cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. http://purl.obolibrary.org/obo/GO_0021703 locus ceruleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021704 locus ceruleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021705 locus ceruleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021706 locus ceruleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. http://purl.obolibrary.org/obo/GO_0021707 cerebellar granule cell differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021708 Lugaro cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021710 cerebellar stellate cell differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. http://purl.obolibrary.org/obo/GO_0021718 superior olivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021719 superior olivary nucleus morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021720 superior olivary nucleus formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021722 superior olivary nucleus maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. http://purl.obolibrary.org/obo/GO_0021732 midbrain-hindbrain boundary maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. http://purl.obolibrary.org/obo/GO_0021743 hypoglossal nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021753 superior salivary nucleus development http://purl.obolibrary.org/obo/GO_0021751 salivary nucleus development The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0021756 striatum development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. http://purl.obolibrary.org/obo/GO_0021757 caudate nucleus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/GO_0021758 putamen development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/GO_0021759 globus pallidus development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain. http://purl.obolibrary.org/obo/GO_0021761 limbic system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. http://purl.obolibrary.org/obo/GO_0021768 nucleus accumbens development http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia. http://purl.obolibrary.org/obo/GO_0021773 striatal medium spiny neuron differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum. http://purl.obolibrary.org/obo/GO_0021783 preganglionic parasympathetic fiber development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion. http://purl.obolibrary.org/obo/GO_0021794 thalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process in which the thalamus changes over time, from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0021795 cerebral cortex cell migration http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration The orderly movement of cells from one site to another in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021799 cerebral cortex radially oriented cell migration http://purl.obolibrary.org/obo/GO_0021795 cerebral cortex cell migration The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. http://purl.obolibrary.org/obo/GO_0021801 cerebral cortex radial glia-guided migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021814 cell motility involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0048870 cell motility The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. http://purl.obolibrary.org/obo/GO_0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. http://purl.obolibrary.org/obo/GO_0021819 layer formation in cerebral cortex http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021822 negative regulation of cell motility involved in cerebral cortex radial glia guided migration http://purl.obolibrary.org/obo/GO_1903976 negative regulation of glial cell migration The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021826 substrate-independent telencephalic tangential migration http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact. http://purl.obolibrary.org/obo/GO_0021830 interneuron migration from the subpallium to the cortex http://purl.obolibrary.org/obo/GO_0021843 substrate-independent telencephalic tangential interneuron migration The directed movement of interneurons from the subpallium to the cortex during forebrain development. http://purl.obolibrary.org/obo/GO_0021843 substrate-independent telencephalic tangential interneuron migration http://purl.obolibrary.org/obo/GO_0021826 substrate-independent telencephalic tangential migration The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates. http://purl.obolibrary.org/obo/GO_0021846 cell proliferation in forebrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. http://purl.obolibrary.org/obo/GO_0021848 neuroblast division in subpallium http://purl.obolibrary.org/obo/GO_0055057 neuroblast division The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially. http://purl.obolibrary.org/obo/GO_0021852 pyramidal neuron migration to cerebral cortex http://purl.obolibrary.org/obo/GO_0140650 radial glia-guided pyramidal neuron migration The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021853 cerebral cortex GABAergic interneuron migration http://purl.obolibrary.org/obo/GO_1904936 interneuron migration The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021854 hypothalamus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0021859 pyramidal neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. http://purl.obolibrary.org/obo/GO_0021860 pyramidal neuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The progression of a pyramidal neuron from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0021861 forebrain radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021863 forebrain neuroblast differentiation http://purl.obolibrary.org/obo/GO_0014016 neuroblast differentiation The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0021872 forebrain generation of neurons http://purl.obolibrary.org/obo/GO_0048699 generation of neurons The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0021885 forebrain cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another at least one of which is located in the forebrain. http://purl.obolibrary.org/obo/GO_0021892 cerebral cortex GABAergic interneuron differentiation http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021894 cerebral cortex GABAergic interneuron development http://purl.obolibrary.org/obo/GO_0021884 forebrain neuron development The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0021895 cerebral cortex neuron differentiation http://purl.obolibrary.org/obo/GO_0021879 forebrain neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex. http://purl.obolibrary.org/obo/GO_0021896 forebrain astrocyte differentiation http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0021897 forebrain astrocyte development http://purl.obolibrary.org/obo/GO_0014002 astrocyte development The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0021903 rostrocaudal neural tube patterning http://purl.obolibrary.org/obo/GO_0009952 anterior/posterior pattern specification The process in which the neural tube is divided into specific regions along the rostrocaudal axis. http://purl.obolibrary.org/obo/GO_0021905 forebrain-midbrain boundary formation http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the creation of the forebrain-midbrain boundary. http://purl.obolibrary.org/obo/GO_0021906 hindbrain-spinal cord boundary formation http://purl.obolibrary.org/obo/GO_0048859 formation of anatomical boundary The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. http://purl.obolibrary.org/obo/GO_0021953 central nervous system neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development http://purl.obolibrary.org/obo/GO_0048666 neuron development The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. http://purl.obolibrary.org/obo/GO_0021982 pineal gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms. http://purl.obolibrary.org/obo/GO_0021983 pituitary gland development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. http://purl.obolibrary.org/obo/GO_0021984 adenohypophysis development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. http://purl.obolibrary.org/obo/GO_0021985 neurohypophysis development http://purl.obolibrary.org/obo/GO_0048732 gland development The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. http://purl.obolibrary.org/obo/GO_0021987 cerebral cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. http://purl.obolibrary.org/obo/GO_0021988 olfactory lobe development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. http://purl.obolibrary.org/obo/GO_0021989 olfactory cortex development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors. http://purl.obolibrary.org/obo/GO_0021990 neural plate formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. http://purl.obolibrary.org/obo/GO_0021999 neural plate anterior/posterior regionalization http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. http://purl.obolibrary.org/obo/GO_0022008 neurogenesis http://purl.obolibrary.org/obo/GO_0030154 cell differentiation Generation of cells within the nervous system. http://purl.obolibrary.org/obo/GO_0022009 central nervous system vasculogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. http://purl.obolibrary.org/obo/GO_0022010 central nervous system myelination http://purl.obolibrary.org/obo/GO_0042552 myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/GO_0022011 myelination in peripheral nervous system http://purl.obolibrary.org/obo/GO_0042552 myelination The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/GO_0022012 subpallium cell proliferation in forebrain http://purl.obolibrary.org/obo/GO_0021846 cell proliferation in forebrain The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0022029 telencephalon cell migration http://purl.obolibrary.org/obo/GO_0021885 forebrain cell migration The orderly movement of a cell from one site to another at least one of which is located in the telencephalon. http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of glial cells through the telencephalon. http://purl.obolibrary.org/obo/GO_0022031 telencephalon astrocyte cell migration http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration The orderly movement of an astrocyte cell through the telencephalon. http://purl.obolibrary.org/obo/GO_0022032 telencephalon oligodendrocyte cell migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0022033 telencephalon microglial cell migration http://purl.obolibrary.org/obo/GO_0022030 telencephalon glial cell migration The orderly movement of microglial cells through the telencephalon. http://purl.obolibrary.org/obo/GO_0022035 rhombomere cell migration http://purl.obolibrary.org/obo/GO_0021535 cell migration in hindbrain The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. http://purl.obolibrary.org/obo/GO_0022037 metencephalon development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. http://purl.obolibrary.org/obo/GO_0022408 negative regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/GO_0022409 positive regulation of cell-cell adhesion http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion Any process that activates or increases the rate or extent of cell adhesion to another cell. http://purl.obolibrary.org/obo/GO_0022613 ribonucleoprotein complex biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0022898 regulation of transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of transmembrane transporter activity. http://purl.obolibrary.org/obo/GO_0023019 signal transduction involved in regulation of gene expression http://purl.obolibrary.org/obo/GO_0007165 signal transduction Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. http://purl.obolibrary.org/obo/GO_0023023 MHC protein complex binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to a major histocompatibility complex. http://purl.obolibrary.org/obo/GO_0023026 MHC class II protein complex binding http://purl.obolibrary.org/obo/GO_0023023 MHC protein complex binding Binding to a class II major histocompatibility complex. http://purl.obolibrary.org/obo/GO_0023052 signaling http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. http://purl.obolibrary.org/obo/GO_0023061 signal release http://purl.obolibrary.org/obo/GO_0032940 secretion by cell The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. http://purl.obolibrary.org/obo/GO_0030016 myofibril http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process http://purl.obolibrary.org/obo/GO_0009987 cellular process Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0030030 cell projection organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. http://purl.obolibrary.org/obo/GO_0030033 microvillus assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/GO_0030048 actin filament-based movement http://purl.obolibrary.org/obo/GO_0030029 actin filament-based process Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030050 vesicle transport along actin filament http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking Movement of a vesicle along an actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a peptide hormone from a cell. http://purl.obolibrary.org/obo/GO_0030100 regulation of endocytosis http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of endocytosis. http://purl.obolibrary.org/obo/GO_0030133 transport vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. http://purl.obolibrary.org/obo/GO_0030150 protein import into mitochondrial matrix http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together. http://purl.obolibrary.org/obo/GO_0030162 regulation of proteolysis http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein. http://purl.obolibrary.org/obo/GO_0030186 melatonin metabolic process http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/GO_0030187 melatonin biosynthetic process http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/GO_0030199 collagen fibril organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process http://purl.obolibrary.org/obo/GO_0030203 glycosaminoglycan metabolic process The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030213 hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030214 hyaluronan catabolic process http://purl.obolibrary.org/obo/GO_0030212 hyaluronan metabolic process The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid. Hyaluronan is a type of non-sulfated glycosaminoglycan composed of the repeating disaccharide unit beta(1,4)-D-glucuronic acid-beta(1,3)-N-acetyl-D-glucosamine. http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. http://purl.obolibrary.org/obo/GO_0030219 megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0030099 myeloid cell differentiation The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte. http://purl.obolibrary.org/obo/GO_0030224 monocyte differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte. http://purl.obolibrary.org/obo/GO_0030252 growth hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of growth hormone from secretory granules into the blood. http://purl.obolibrary.org/obo/GO_0030263 apoptotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation The compaction of chromatin during apoptosis. http://purl.obolibrary.org/obo/GO_0030264 nuclear fragmentation involved in apoptotic nuclear change http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA. http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0030279 negative regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0030307 positive regulation of cell growth http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030308 negative regulation of cell growth http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. http://purl.obolibrary.org/obo/GO_0030316 osteoclast differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. http://purl.obolibrary.org/obo/GO_0030324 lung development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/GO_0030424 axon http://purl.obolibrary.org/obo/GO_0043005 neuron projection The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. http://purl.obolibrary.org/obo/GO_0030425 dendrite http://purl.obolibrary.org/obo/GO_0043005 neuron projection A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. http://purl.obolibrary.org/obo/GO_0030435 sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043934 sporulation The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/GO_0030436 asexual sporulation http://purl.obolibrary.org/obo/GO_0043934 sporulation The formation of spores derived from the products of an asexual cell division. Examples of this process are found in bacteria and fungi. http://purl.obolibrary.org/obo/GO_0030448 hyphal growth http://purl.obolibrary.org/obo/GO_0030447 filamentous growth Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls. http://purl.obolibrary.org/obo/GO_0030485 smooth muscle contractile fiber http://purl.obolibrary.org/obo/GO_0043292 contractile muscle fiber The contractile fiber of smooth muscle cells. http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane The lipid bilayer surrounding a cytoplasmic vesicle. http://purl.obolibrary.org/obo/GO_0030720 oocyte localization involved in germarium-derived egg chamber formation http://purl.obolibrary.org/obo/GO_0051674 localization of cell Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. http://purl.obolibrary.org/obo/GO_0030849 autosome http://purl.obolibrary.org/obo/GO_0005694 chromosome Any chromosome other than a sex chromosome. http://purl.obolibrary.org/obo/GO_0030851 granulocyte differentiation http://purl.obolibrary.org/obo/GO_0002573 myeloid leukocyte differentiation The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils. http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/GO_0030853 negative regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/GO_0030854 positive regulation of granulocyte differentiation http://purl.obolibrary.org/obo/GO_0030852 regulation of granulocyte differentiation Any process that activates or increases the frequency, rate or extent of granulocyte differentiation. http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency or rate of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/GO_0030886 negative regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/GO_0030887 positive regulation of myeloid dendritic cell activation http://purl.obolibrary.org/obo/GO_0030885 regulation of myeloid dendritic cell activation Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation. http://purl.obolibrary.org/obo/GO_0030900 forebrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). http://purl.obolibrary.org/obo/GO_0030901 midbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). http://purl.obolibrary.org/obo/GO_0030902 hindbrain development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). http://purl.obolibrary.org/obo/GO_0030903 notochord development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/GO_0030917 midbrain-hindbrain boundary development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. http://purl.obolibrary.org/obo/GO_0031022 nuclear migration along microfilament http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0031045 dense core granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted. http://purl.obolibrary.org/obo/GO_0031076 embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0048568 embryonic organ development The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. http://purl.obolibrary.org/obo/GO_0031112 positive regulation of microtubule polymerization or depolymerization http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. http://purl.obolibrary.org/obo/GO_0031115 negative regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031116 positive regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that activates or increases the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031117 positive regulation of microtubule depolymerization http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization Any process that activates or increases the frequency, rate or extent of microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0031143 pseudopodium http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding. http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of the plasma membrane surrounding the leading edge of a motile cell. http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement. http://purl.obolibrary.org/obo/GO_0031269 pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane. http://purl.obolibrary.org/obo/GO_0031270 pseudopodium retraction http://purl.obolibrary.org/obo/GO_0031268 pseudopodium organization The myosin-based contraction and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0031272 regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/GO_0031273 negative regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/GO_0031274 positive regulation of pseudopodium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia. http://purl.obolibrary.org/obo/GO_0031338 regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031339 negative regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031340 positive regulation of vesicle fusion http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of vesicle fusion. http://purl.obolibrary.org/obo/GO_0031445 regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0010468 regulation of gene expression Any process that modulates the frequency, rate, extent or location of heterochromatin formation. http://purl.obolibrary.org/obo/GO_0031452 negative regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation. http://purl.obolibrary.org/obo/GO_0031453 positive regulation of heterochromatin formation http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of heterochromatin formation. http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization http://purl.obolibrary.org/obo/GO_0033036 macromolecule localization A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0031507 heterochromatin formation http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation. http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction http://purl.obolibrary.org/obo/GO_0045202 synapse The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential. http://purl.obolibrary.org/obo/GO_0031641 regulation of myelination http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/GO_0031642 negative regulation of myelination http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/GO_0031643 positive regulation of myelination http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. http://purl.obolibrary.org/obo/GO_0031645 negative regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031646 positive regulation of nervous system process http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that activates or increases the frequency, rate or extent of a neurophysiological process. http://purl.obolibrary.org/obo/GO_0031727 CCR2 chemokine receptor binding http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding Binding to a CCR2 chemokine receptor. http://purl.obolibrary.org/obo/GO_0032043 mitochondrial DNA catabolic process http://purl.obolibrary.org/obo/GO_0006308 DNA catabolic process The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA. http://purl.obolibrary.org/obo/GO_0032055 negative regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032057 negative regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032058 positive regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032059 bleb http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/GO_0032060 bleb assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses. http://purl.obolibrary.org/obo/GO_0032065 maintenance of protein location in cell cortex http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell A process in which a protein or protein complex is maintained in a specific location in the cell cortex. http://purl.obolibrary.org/obo/GO_0032077 positive regulation of deoxyribonuclease activity http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid. http://purl.obolibrary.org/obo/GO_0032092 positive regulation of protein binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that activates or increases the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding a dense core granule. http://purl.obolibrary.org/obo/GO_0032179 germ tube http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The slender tubular outgrowth first produced by most spores in germination. http://purl.obolibrary.org/obo/GO_0032225 regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/GO_0032226 positive regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0032225 regulation of synaptic transmission, dopaminergic Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/GO_0032227 negative regulation of synaptic transmission, dopaminergic http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine. http://purl.obolibrary.org/obo/GO_0032228 regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/GO_0032229 negative regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/GO_0032230 positive regulation of synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0032228 regulation of synaptic transmission, GABAergic Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA). http://purl.obolibrary.org/obo/GO_0032231 regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032232 negative regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032233 positive regulation of actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. http://purl.obolibrary.org/obo/GO_0032239 regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032240 negative regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032241 positive regulation of nucleobase-containing compound transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0032253 dense core granule localization http://purl.obolibrary.org/obo/GO_0032252 secretory granule localization Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0032272 negative regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032273 positive regulation of protein polymerization http://purl.obolibrary.org/obo/GO_0032271 regulation of protein polymerization Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. http://purl.obolibrary.org/obo/GO_0032274 gonadotropin secretion http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone. http://purl.obolibrary.org/obo/GO_0032275 luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0032274 gonadotropin secretion The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary. http://purl.obolibrary.org/obo/GO_0032276 regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046883 regulation of hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/GO_0032277 negative regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/GO_0032278 positive regulation of gonadotropin secretion http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin. http://purl.obolibrary.org/obo/GO_0032288 myelin assembly http://purl.obolibrary.org/obo/GO_0010927 cellular component assembly involved in morphogenesis The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. http://purl.obolibrary.org/obo/GO_0032289 central nervous system myelin formation http://purl.obolibrary.org/obo/GO_0032288 myelin assembly The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. http://purl.obolibrary.org/obo/GO_0032290 peripheral nervous system myelin formation http://purl.obolibrary.org/obo/GO_0032288 myelin assembly The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0032291 axon ensheathment in central nervous system http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. http://purl.obolibrary.org/obo/GO_0032292 peripheral nervous system axon ensheathment http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032331 negative regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032332 positive regulation of chondrocyte differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. http://purl.obolibrary.org/obo/GO_0032351 negative regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/GO_0032352 positive regulation of hormone metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. http://purl.obolibrary.org/obo/GO_0032353 negative regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/GO_0032369 negative regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032370 positive regulation of lipid transport http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032377 regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032378 negative regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032379 positive regulation of intracellular lipid transport http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032387 negative regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032388 positive regulation of intracellular transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. http://purl.obolibrary.org/obo/GO_0032410 negative regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops or reduces the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032411 positive regulation of transporter activity http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the activity of a transporter. http://purl.obolibrary.org/obo/GO_0032414 positive regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034767 positive regulation of monoatomic ion transmembrane transport Any process that activates or increases the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032418 lysosome localization http://purl.obolibrary.org/obo/GO_1990849 vacuolar localization Any process in which a lysosome is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032528 microvillus organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. http://purl.obolibrary.org/obo/GO_0032530 regulation of microvillus organization http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. http://purl.obolibrary.org/obo/GO_0032534 regulation of microvillus assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly A process that modulates the formation of a microvillus. http://purl.obolibrary.org/obo/GO_0032543 mitochondrial translation http://purl.obolibrary.org/obo/GO_0006412 translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. http://purl.obolibrary.org/obo/GO_0032544 plastid translation http://purl.obolibrary.org/obo/GO_0009657 plastid organization The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. http://purl.obolibrary.org/obo/GO_0032589 neuron projection membrane http://purl.obolibrary.org/obo/GO_0031256 leading edge membrane The portion of the plasma membrane surrounding a neuron projection. http://purl.obolibrary.org/obo/GO_0032590 dendrite membrane http://purl.obolibrary.org/obo/GO_0032589 neuron projection membrane The portion of the plasma membrane surrounding a dendrite. http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer http://purl.obolibrary.org/obo/GO_0006886 intracellular protein transport The directed movement of a protein from one location to another within a lipid bilayer. http://purl.obolibrary.org/obo/GO_0032790 ribosome disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits. http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/GO_0032839 dendrite cytoplasm http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm All of the contents of a dendrite, excluding the surrounding plasma membrane. http://purl.obolibrary.org/obo/GO_0032871 regulation of karyogamy http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. http://purl.obolibrary.org/obo/GO_0032878 regulation of establishment or maintenance of cell polarity http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032891 negative regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032892 positive regulation of organic acid transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0032938 negative regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0032939 positive regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0032056 positive regulation of translation in response to stress Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue http://purl.obolibrary.org/obo/GO_0046903 secretion The controlled release of a substance by a tissue. http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070661 leukocyte proliferation The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form. http://purl.obolibrary.org/obo/GO_0032944 regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/GO_0032945 negative regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070664 negative regulation of leukocyte proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/GO_0032946 positive regulation of mononuclear cell proliferation http://purl.obolibrary.org/obo/GO_0070665 positive regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0032964 collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0032965 regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032966 negative regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032967 positive regulation of collagen biosynthetic process http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0032973 amino acid export across plasma membrane http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane The directed movement of amino acids from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0032975 amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport The directed movement of amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033033 negative regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033034 positive regulation of myeloid cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process. http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome. http://purl.obolibrary.org/obo/GO_0033046 negative regulation of sister chromatid segregation http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation. http://purl.obolibrary.org/obo/GO_0033048 negative regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033059 cellular pigmentation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The deposition or aggregation of coloring matter in a cell. http://purl.obolibrary.org/obo/GO_0033157 regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0033239 negative regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/GO_0033240 positive regulation of amine metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. http://purl.obolibrary.org/obo/GO_0033241 regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033242 negative regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033243 positive regulation of amine catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. http://purl.obolibrary.org/obo/GO_0033278 cell proliferation in midbrain http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. http://purl.obolibrary.org/obo/GO_0033326 cerebrospinal fluid secretion http://purl.obolibrary.org/obo/GO_0032941 secretion by tissue The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces. http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within an organelle. http://purl.obolibrary.org/obo/GO_0033366 protein localization to secretory granule http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a secretory granule. http://purl.obolibrary.org/obo/GO_0033371 T cell secretory granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. http://purl.obolibrary.org/obo/GO_0033504 floor plate development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the floor plate over time from its initial formation until its mature state. http://purl.obolibrary.org/obo/GO_0033505 floor plate morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structure of the floor plate is generated and organized. http://purl.obolibrary.org/obo/GO_0033602 negative regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/GO_0033603 positive regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0032276 regulation of gonadotropin secretion Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/GO_0033685 negative regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/GO_0033686 positive regulation of luteinizing hormone secretion http://purl.obolibrary.org/obo/GO_0033684 regulation of luteinizing hormone secretion Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone. http://purl.obolibrary.org/obo/GO_0033696 heterochromatin boundary formation http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization A process that forms a boundary that limits the spreading of heterochromatin along a chromosome. http://purl.obolibrary.org/obo/GO_0033750 ribosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization A process in which a ribosome is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0034067 protein localization to Golgi apparatus http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0034097 response to cytokine http://purl.obolibrary.org/obo/GO_1901652 response to peptide Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. http://purl.obolibrary.org/obo/GO_0034101 erythrocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis Any process of regulating the production and elimination of erythrocytes within an organism. http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/GO_0034104 negative regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/GO_0034105 positive regulation of tissue remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that activates or increases the frequency, rate, or extent of tissue remodeling. http://purl.obolibrary.org/obo/GO_0034242 negative regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0034251 regulation of amide catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. http://purl.obolibrary.org/obo/GO_0034252 negative regulation of amide catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. http://purl.obolibrary.org/obo/GO_0034253 positive regulation of amide catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides. http://purl.obolibrary.org/obo/GO_0034487 vacuolar amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0003333 amino acid transmembrane transport The process in which an amino acid is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/GO_0034762 regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034766 negative regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034767 positive regulation of monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0035107 appendage morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. http://purl.obolibrary.org/obo/GO_0035270 endocrine system development http://purl.obolibrary.org/obo/GO_0048731 system development Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. http://purl.obolibrary.org/obo/GO_0035869 ciliary transition zone http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. http://purl.obolibrary.org/obo/GO_0036477 somatodendritic compartment http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. http://purl.obolibrary.org/obo/GO_0040011 locomotion http://purl.obolibrary.org/obo/GO_0008150 biological process Self-propelled movement of a cell or organism from one location to another. http://purl.obolibrary.org/obo/GO_0040020 regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. http://purl.obolibrary.org/obo/GO_0042102 positive regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/GO_0042130 negative regulation of T cell proliferation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents or reduces the rate or extent of T cell proliferation. http://purl.obolibrary.org/obo/GO_0042306 regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0042307 positive regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0042308 negative regulation of protein import into nucleus http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus. http://purl.obolibrary.org/obo/GO_0042552 myelination http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex http://purl.obolibrary.org/obo/GO_0098797 plasma membrane protein complex A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen. http://purl.obolibrary.org/obo/GO_0043022 ribosome binding http://purl.obolibrary.org/obo/GO_0043021 ribonucleoprotein complex binding Binding to a ribosome. http://purl.obolibrary.org/obo/GO_0043025 neuronal cell body http://purl.obolibrary.org/obo/GO_0044297 cell body The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. http://purl.obolibrary.org/obo/GO_0043062 extracellular structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. http://purl.obolibrary.org/obo/GO_0043069 negative regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043177 organic acid binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an organic acid, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043233 organelle lumen http://purl.obolibrary.org/obo/GO_0031974 membrane-enclosed lumen The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen. http://purl.obolibrary.org/obo/GO_0043253 chloroplast ribosome http://purl.obolibrary.org/obo/GO_0009547 plastid ribosome A ribosome contained within a chloroplast. http://purl.obolibrary.org/obo/GO_0043297 apical junction assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of protein binding. http://purl.obolibrary.org/obo/GO_0043434 response to peptide hormone http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/GO_0043473 pigmentation http://purl.obolibrary.org/obo/GO_0008150 biological process The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0043556 regulation of translation in response to oxidative stress http://purl.obolibrary.org/obo/GO_0032055 negative regulation of translation in response to stress Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0043588 skin development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. http://purl.obolibrary.org/obo/GO_0043934 sporulation http://purl.obolibrary.org/obo/GO_0032502 developmental process The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/GO_0043935 sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0034293 sexual sporulation The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and desiccation resistance, and/or for reproduction. http://purl.obolibrary.org/obo/GO_0044057 regulation of system process http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044092 negative regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044093 positive regulation of molecular function http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0044217 other organism part http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure Any constituent part of a secondary organism with which the first organism is interacting. http://purl.obolibrary.org/obo/GO_0044409 symbiont entry into host http://purl.obolibrary.org/obo/GO_0051701 biological process involved in interaction with host Entry of a symbiont into the body, tissues, or cells of a host organism as part of the symbiont life cycle. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044423 virion component http://purl.obolibrary.org/obo/GO_0005575 cellular_component Any constituent part of a virion, a complete fully infectious extracellular virus particle. http://purl.obolibrary.org/obo/GO_0044782 cilium organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a macromolecular complex. http://purl.obolibrary.org/obo/GO_0045168 cell-cell signaling involved in cell fate commitment http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. http://purl.obolibrary.org/obo/GO_0045185 maintenance of protein location http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away. http://purl.obolibrary.org/obo/GO_0045202 synapse http://purl.obolibrary.org/obo/GO_0030054 cell junction The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that modulates the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/GO_0045581 negative regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/GO_0045582 positive regulation of T cell differentiation http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell differentiation. http://purl.obolibrary.org/obo/GO_0045619 regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/GO_0045620 negative regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/GO_0045621 positive regulation of lymphocyte differentiation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. http://purl.obolibrary.org/obo/GO_0045763 negative regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/GO_0045764 positive regulation of amino acid metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. http://purl.obolibrary.org/obo/GO_0045778 positive regulation of ossification http://purl.obolibrary.org/obo/GO_0030278 regulation of ossification Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. http://purl.obolibrary.org/obo/GO_0045835 negative regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045836 positive regulation of meiotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of meiosis. http://purl.obolibrary.org/obo/GO_0045840 positive regulation of mitotic nuclear division http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitosis. http://purl.obolibrary.org/obo/GO_0045926 negative regulation of growth http://purl.obolibrary.org/obo/GO_0048519 negative regulation of biological process Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045927 positive regulation of growth http://purl.obolibrary.org/obo/GO_0048518 positive regulation of biological process Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. http://purl.obolibrary.org/obo/GO_0045947 negative regulation of translational initiation http://purl.obolibrary.org/obo/GO_0017148 negative regulation of translation Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0045948 positive regulation of translational initiation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translational initiation. http://purl.obolibrary.org/obo/GO_0046466 membrane lipid catabolic process http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane. http://purl.obolibrary.org/obo/GO_0046660 female sex differentiation http://purl.obolibrary.org/obo/GO_0007548 sex differentiation The establishment of the sex of a female organism by physical differentiation. http://purl.obolibrary.org/obo/GO_0046887 positive regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0046888 negative regulation of hormone secretion http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. http://purl.obolibrary.org/obo/GO_0047497 mitochondrion transport along microtubule http://purl.obolibrary.org/obo/GO_0034643 establishment of mitochondrion localization, microtubule-mediated The directed movement of a mitochondrion along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0048020 CCR chemokine receptor binding http://purl.obolibrary.org/obo/GO_0042379 chemokine receptor binding Binding to a CCR chemokine receptor. http://purl.obolibrary.org/obo/GO_0048483 autonomic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. http://purl.obolibrary.org/obo/GO_0048486 parasympathetic nervous system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. http://purl.obolibrary.org/obo/GO_0048521 negative regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048534 hematopoietic or lymphoid organ development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. http://purl.obolibrary.org/obo/GO_0048545 response to steroid hormone http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0048730 epidermis morphogenesis http://purl.obolibrary.org/obo/GO_0002009 morphogenesis of an epithelium The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/GO_0048736 appendage development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. http://purl.obolibrary.org/obo/GO_0048857 neural nucleus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. http://purl.obolibrary.org/obo/GO_0048860 glioblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a glioblast into daughter cells. http://purl.obolibrary.org/obo/GO_0050670 regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/GO_0050671 positive regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation Any process that activates or increases the rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/GO_0050672 negative regulation of lymphocyte proliferation http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. http://purl.obolibrary.org/obo/GO_0050714 positive regulation of protein secretion http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. http://purl.obolibrary.org/obo/GO_0050770 regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. http://purl.obolibrary.org/obo/GO_0050771 negative regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0099177 regulation of trans-synaptic signaling Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission. http://purl.obolibrary.org/obo/GO_0050805 negative regulation of synaptic transmission http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. http://purl.obolibrary.org/obo/GO_0050870 positive regulation of T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that activates or increases the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0050931 pigment cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. http://purl.obolibrary.org/obo/GO_0051017 actin filament bundle assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. http://purl.obolibrary.org/obo/GO_0051054 positive regulation of DNA metabolic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA. http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051179 localization http://purl.obolibrary.org/obo/GO_0008150 biological process Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. http://purl.obolibrary.org/obo/GO_0051223 regulation of protein transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051235 maintenance of location http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0060255 regulation of macromolecule metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051247 positive regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051248 negative regulation of protein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051250 negative regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051251 positive regulation of lymphocyte activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that activates or increases the frequency, rate or extent of lymphocyte activation. http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA. http://purl.obolibrary.org/obo/GO_0051644 plastid localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051647 nucleus localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051648 vesicle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051655 maintenance of vesicle location http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization The directed movement of an organelle to a specific location. http://purl.obolibrary.org/obo/GO_0051668 localization within membrane http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. http://purl.obolibrary.org/obo/GO_0051674 localization of cell http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which a cell is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051701 biological process involved in interaction with host http://purl.obolibrary.org/obo/GO_0044403 biological process involved in symbiotic interaction An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism. http://purl.obolibrary.org/obo/GO_0051781 positive regulation of cell division http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051782 negative regulation of cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. http://purl.obolibrary.org/obo/GO_0051875 pigment granule localization http://purl.obolibrary.org/obo/GO_0051648 vesicle localization Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_0051904 pigment granule transport http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051905 establishment of pigment granule localization http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The directed movement of a pigment granule to a specific location. http://purl.obolibrary.org/obo/GO_0051932 synaptic transmission, GABAergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of gamma-aminobutyric acid (GABA). from a presynapse, across a chemical synapse, the subsequent activation of GABA receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051961 negative regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051962 positive regulation of nervous system development http://purl.obolibrary.org/obo/GO_0051960 regulation of nervous system development Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. http://purl.obolibrary.org/obo/GO_0051983 regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010564 regulation of cell cycle process Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0051985 negative regulation of chromosome segregation http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets. http://purl.obolibrary.org/obo/GO_0055001 muscle cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. http://purl.obolibrary.org/obo/GO_0055057 neuroblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0055123 digestive system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0060019 radial glial cell differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060142 regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0060143 positive regulation of syncytium formation by plasma membrane fusion http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. http://purl.obolibrary.org/obo/GO_0060170 ciliary membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a cilium. http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification http://purl.obolibrary.org/obo/GO_0007389 pattern specification process The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. http://purl.obolibrary.org/obo/GO_0060897 neural plate regionalization http://purl.obolibrary.org/obo/GO_0060896 neural plate pattern specification The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. http://purl.obolibrary.org/obo/GO_0060986 endocrine hormone secretion http://purl.obolibrary.org/obo/GO_0046879 hormone secretion The regulated release of a hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0061036 positive regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061037 negative regulation of cartilage development http://purl.obolibrary.org/obo/GO_0061035 regulation of cartilage development Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0061458 reproductive system development http://purl.obolibrary.org/obo/GO_0048731 system development The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. http://purl.obolibrary.org/obo/GO_0065010 extracellular membrane-bounded organelle http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0070587 regulation of cell-cell adhesion involved in gastrulation http://purl.obolibrary.org/obo/GO_0022407 regulation of cell-cell adhesion Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation. http://purl.obolibrary.org/obo/GO_0070633 transepithelial transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a substance from one side of an epithelium to the other. http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070664 negative regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070665 positive regulation of leukocyte proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. http://purl.obolibrary.org/obo/GO_0070828 heterochromatin organization http://purl.obolibrary.org/obo/GO_0006325 chromatin organization Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. http://purl.obolibrary.org/obo/GO_0071345 cellular response to cytokine stimulus http://purl.obolibrary.org/obo/GO_0034097 response to cytokine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus. http://purl.obolibrary.org/obo/GO_0071375 cellular response to peptide hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. http://purl.obolibrary.org/obo/GO_0071495 cellular response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. http://purl.obolibrary.org/obo/GO_0071826 protein-RNA complex organization http://purl.obolibrary.org/obo/GO_0043933 protein-containing complex organization Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex. http://purl.obolibrary.org/obo/GO_0072384 organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0097154 GABAergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron. http://purl.obolibrary.org/obo/GO_0097176 epoxide metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers. http://purl.obolibrary.org/obo/GO_0097708 intracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the intracellular region. http://purl.obolibrary.org/obo/GO_0099501 exocytic vesicle membrane http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane The lipid bilayer surrounding an exocytic vesicle. http://purl.obolibrary.org/obo/GO_0099503 secretory vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. http://purl.obolibrary.org/obo/GO_0099515 actin filament-based transport http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The transport of organelles or other particles from one location in the cell to another along actin filaments. http://purl.obolibrary.org/obo/GO_0099518 vesicle cytoskeletal trafficking http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0099738 cell cortex region http://purl.obolibrary.org/obo/GO_0099568 cytoplasmic region The complete extent of cell cortex that underlies some some region of the plasma membrane. http://purl.obolibrary.org/obo/GO_1901161 primary amino compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of primary amino compound. http://purl.obolibrary.org/obo/GO_1901503 ether biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of ether. http://purl.obolibrary.org/obo/GO_1901652 response to peptide http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/GO_1901879 regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043244 regulation of protein-containing complex disassembly Any process that modulates the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1901881 positive regulation of protein depolymerization http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly Any process that activates or increases the frequency, rate or extent of protein depolymerization. http://purl.obolibrary.org/obo/GO_1902679 negative regulation of RNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051253 negative regulation of RNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process. http://purl.obolibrary.org/obo/GO_1902905 positive regulation of supramolecular fiber organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly http://purl.obolibrary.org/obo/GO_0022411 cellular component disassembly The disaggregation of an organelle into its constituent components. http://purl.obolibrary.org/obo/GO_1903115 regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0032970 regulation of actin filament-based process Any process that modulates the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation http://purl.obolibrary.org/obo/GO_0002521 leukocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell. http://purl.obolibrary.org/obo/GO_1903353 regulation of nucleus organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of nucleus organization. http://purl.obolibrary.org/obo/GO_1903976 negative regulation of glial cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_1904936 interneuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of an interneuron from one site to another. http://purl.obolibrary.org/obo/GO_1905268 negative regulation of chromatin organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905269 positive regulation of chromatin organization http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization Any process that activates or increases the frequency, rate or extent of chromatin organization. http://purl.obolibrary.org/obo/GO_1905332 positive regulation of morphogenesis of an epithelium http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. http://purl.obolibrary.org/obo/GO_1905879 regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905880 negative regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1905881 positive regulation of oogenesis http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oogenesis. http://purl.obolibrary.org/obo/GO_1990351 transporter complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells. http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A macromolecular complex that contains both RNA and protein molecules. http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000107 negative regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000108 positive regulation of leukocyte apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process. http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that modulates the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000146 negative regulation of cell motility http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000147 positive regulation of cell motility http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell motility. http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_2000279 negative regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_2000573 positive regulation of DNA biosynthetic process http://purl.obolibrary.org/obo/GO_2000278 regulation of DNA biosynthetic process Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process. http://purl.obolibrary.org/obo/GO_2001251 negative regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_2001252 positive regulation of chromosome organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of chromosome organization. http://purl.obolibrary.org/obo/GO_0034293 sexual sporulation http://purl.obolibrary.org/obo/GO_0043934 sporulation The formation of spores derived from the products of meiosis. http://purl.obolibrary.org/obo/GO_0034301 endospore formation http://purl.obolibrary.org/obo/GO_0043936 asexual sporulation resulting in formation of a cellular spore The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions. http://purl.obolibrary.org/obo/GO_0034305 regulation of asexual sporulation http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis. http://purl.obolibrary.org/obo/GO_0034306 regulation of sexual sporulation http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae. http://purl.obolibrary.org/obo/GO_0034330 cell junction organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. http://purl.obolibrary.org/obo/GO_0034349 glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system. http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034351 negative regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034352 positive regulation of glial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034390 smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels. http://purl.obolibrary.org/obo/GO_0034391 regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034392 negative regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034393 positive regulation of smooth muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process. http://purl.obolibrary.org/obo/GO_0034436 glycoprotein transport http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0034486 vacuolar transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a solute is transported from one side of the vacuolar membrane to the other. http://purl.obolibrary.org/obo/GO_0034489 neutral amino acid transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0034491 neutral amino acid transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0032975 amino acid transmembrane import into vacuole The directed movement of neutral amino acids into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle Any process in which a protein is transported to, or maintained at, a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0034614 cellular response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals. http://purl.obolibrary.org/obo/GO_0034642 mitochondrion migration along actin filament http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization The directed movement of a mitochondrion along a microfilament, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0034643 establishment of mitochondrion localization, microtubule-mediated http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization The directed movement of the mitochondrion to a specific location, by a process involving microtubules. http://purl.obolibrary.org/obo/GO_0034763 negative regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034764 positive regulation of transmembrane transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0034769 basement membrane disassembly http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion. http://purl.obolibrary.org/obo/GO_0035148 tube formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. http://purl.obolibrary.org/obo/GO_0035190 syncytial nuclear migration http://purl.obolibrary.org/obo/GO_0007097 nuclear migration The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisions and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. http://purl.obolibrary.org/obo/GO_0035234 ectopic germ cell programmed cell death http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo. http://purl.obolibrary.org/obo/GO_0035249 synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0035260 internal genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. http://purl.obolibrary.org/obo/GO_0035261 external genitalia morphogenesis http://purl.obolibrary.org/obo/GO_0035112 genitalia morphogenesis The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. http://purl.obolibrary.org/obo/GO_0035264 multicellular organism growth http://purl.obolibrary.org/obo/GO_0048589 developmental growth The increase in size or mass of an entire multicellular organism, as opposed to cell growth. http://purl.obolibrary.org/obo/GO_0035290 trunk segmentation http://purl.obolibrary.org/obo/GO_0035282 segmentation Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton A process in which a protein is transported to, or maintained at, a microtubule. http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0035562 negative regulation of chromatin binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0035563 positive regulation of chromatin binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase. http://purl.obolibrary.org/obo/GO_0035577 azurophil granule membrane http://purl.obolibrary.org/obo/GO_0030667 secretory granule membrane The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. http://purl.obolibrary.org/obo/GO_0035592 establishment of protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization The directed movement of a protein to a specific location within the extracellular region. http://purl.obolibrary.org/obo/GO_0035694 mitochondrial protein catabolic process http://purl.obolibrary.org/obo/GO_0030163 protein catabolic process The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure. http://purl.obolibrary.org/obo/GO_0035700 astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_0043615 astrocyte cell migration The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0035701 hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. http://purl.obolibrary.org/obo/GO_0035702 monocyte homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0035719 tRNA import into nucleus http://purl.obolibrary.org/obo/GO_0051031 tRNA transport The directed movement of tRNA from the cytoplasm to the nucleus. http://purl.obolibrary.org/obo/GO_0035735 intraciliary transport involved in cilium assembly http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. http://purl.obolibrary.org/obo/GO_0035736 cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_0035767 endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). http://purl.obolibrary.org/obo/GO_0035779 angioblast cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). http://purl.obolibrary.org/obo/GO_0035855 megakaryocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow. http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell. http://purl.obolibrary.org/obo/GO_0035887 aortic smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0035886 vascular associated smooth muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta. http://purl.obolibrary.org/obo/GO_0035904 aorta development http://purl.obolibrary.org/obo/GO_0060840 artery development The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0035905 ascending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035906 descending aorta development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035907 dorsal aorta development http://purl.obolibrary.org/obo/GO_0035904 aorta development The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0035910 ascending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035911 descending aorta morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035912 dorsal aorta morphogenesis http://purl.obolibrary.org/obo/GO_0035909 aorta morphogenesis The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell The regulated release of any steroid that acts as a hormone into the circulatory system. http://purl.obolibrary.org/obo/GO_0035935 androgen secretion http://purl.obolibrary.org/obo/GO_0035929 steroid hormone secretion The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates. http://purl.obolibrary.org/obo/GO_0035981 tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_0098528 skeletal muscle fiber differentiation The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell. http://purl.obolibrary.org/obo/GO_0035990 tendon cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance. http://purl.obolibrary.org/obo/GO_0035992 tendon formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. http://purl.obolibrary.org/obo/GO_0036035 osteoclast development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/GO_0036135 Schwann cell migration http://purl.obolibrary.org/obo/GO_0008347 glial cell migration The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintenance and function. http://purl.obolibrary.org/obo/GO_0036145 dendritic cell homeostasis http://purl.obolibrary.org/obo/GO_0001776 leukocyte homeostasis The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0036160 melanocyte-stimulating hormone secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation. http://purl.obolibrary.org/obo/GO_0036179 osteoclast maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes. http://purl.obolibrary.org/obo/GO_0036194 muscle cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. http://purl.obolibrary.org/obo/GO_0036195 muscle cell projection membrane http://purl.obolibrary.org/obo/GO_0031253 cell projection membrane The portion of the plasma membrane surrounding a muscle cell projection. http://purl.obolibrary.org/obo/GO_0036230 granulocyte activation http://purl.obolibrary.org/obo/GO_0002274 myeloid leukocyte activation The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0036334 epidermal stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells. http://purl.obolibrary.org/obo/GO_0036484 trunk neural crest cell migration http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo. http://purl.obolibrary.org/obo/GO_0036504 Golgi membrane fusion http://purl.obolibrary.org/obo/GO_0090174 organelle membrane fusion The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. http://purl.obolibrary.org/obo/GO_0036520 astrocyte-dopaminergic neuron signaling http://purl.obolibrary.org/obo/GO_0150098 glial cell-neuron signaling Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron. http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040013 negative regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. http://purl.obolibrary.org/obo/GO_0040015 negative regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0040014 regulation of multicellular organism growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040016 embryonic cleavage http://purl.obolibrary.org/obo/GO_0051301 cell division The first few specialized divisions of an activated animal egg. http://purl.obolibrary.org/obo/GO_0040017 positive regulation of locomotion http://purl.obolibrary.org/obo/GO_0040012 regulation of locomotion Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. http://purl.obolibrary.org/obo/GO_0040018 positive regulation of multicellular organism growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. http://purl.obolibrary.org/obo/GO_0040019 positive regulation of embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of embryonic development. http://purl.obolibrary.org/obo/GO_0040034 regulation of development, heterochronic http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached. http://purl.obolibrary.org/obo/GO_0042053 regulation of dopamine metabolic process http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. http://purl.obolibrary.org/obo/GO_0042065 glial cell growth http://purl.obolibrary.org/obo/GO_0048588 developmental cell growth Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. http://purl.obolibrary.org/obo/GO_0042069 regulation of catecholamine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. http://purl.obolibrary.org/obo/GO_0042073 intraciliary transport http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0042078 germ-line stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes. http://purl.obolibrary.org/obo/GO_0042103 positive regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation Any process that activates or increases the rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/GO_0042173 regulation of sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that modulates the frequency, rate or extent of spore formation. http://purl.obolibrary.org/obo/GO_0042176 regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0042177 negative regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process. http://purl.obolibrary.org/obo/GO_0042268 regulation of cytolysis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm. http://purl.obolibrary.org/obo/GO_0042415 norepinephrine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042417 dopamine metabolic process http://purl.obolibrary.org/obo/GO_0006584 catecholamine metabolic process The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0042420 dopamine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0042421 norepinephrine biosynthetic process http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042422 norepinephrine catabolic process http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0042423 catecholamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042424 catecholamine catabolic process http://purl.obolibrary.org/obo/GO_0019614 catechol-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0042428 serotonin metabolic process http://purl.obolibrary.org/obo/GO_0042430 indole-containing compound metabolic process The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042429 serotonin catabolic process http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process http://purl.obolibrary.org/obo/GO_0009056 catabolic process The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042442 melatonin catabolic process http://purl.obolibrary.org/obo/GO_0042436 indole-containing compound catabolic process The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine). http://purl.obolibrary.org/obo/GO_0042462 eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0042461 photoreceptor cell development Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. http://purl.obolibrary.org/obo/GO_0042478 regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042479 positive regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042480 negative regulation of eye photoreceptor cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. http://purl.obolibrary.org/obo/GO_0042582 azurophil granule http://purl.obolibrary.org/obo/GO_0030141 secretory granule Primary lysosomal granule readily stainable with a Romanowsky stain. http://purl.obolibrary.org/obo/GO_0042613 MHC class II protein complex http://purl.obolibrary.org/obo/GO_0042611 MHC protein complex A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen. http://purl.obolibrary.org/obo/GO_0042644 chloroplast nucleoid http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid The region of a chloroplast to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042648 chloroplast chromosome http://purl.obolibrary.org/obo/GO_0009508 plastid chromosome A circular DNA molecule containing chloroplast encoded genes. http://purl.obolibrary.org/obo/GO_0042670 retinal cone cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. http://purl.obolibrary.org/obo/GO_0042996 regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0042997 negative regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0042998 positive regulation of Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. http://purl.obolibrary.org/obo/GO_0043001 Golgi to plasma membrane protein transport http://purl.obolibrary.org/obo/GO_0015031 protein transport The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0002694 regulation of leukocyte activation Any process that modulates the frequency or rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0043031 negative regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. http://purl.obolibrary.org/obo/GO_0043032 positive regulation of macrophage activation http://purl.obolibrary.org/obo/GO_0043030 regulation of macrophage activation Any process that stimulates, induces or increases the rate of macrophage activation. http://purl.obolibrary.org/obo/GO_0043038 amino acid activation http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule. http://purl.obolibrary.org/obo/GO_0043143 regulation of translation by machinery localization http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0043167 ion binding http://purl.obolibrary.org/obo/GO_0036094 small molecule binding Binding to an ion, a charged atoms or groups of atoms. http://purl.obolibrary.org/obo/GO_0043184 vascular endothelial growth factor receptor 2 binding http://purl.obolibrary.org/obo/GO_0005172 vascular endothelial growth factor receptor binding Binding to a vascular endothelial growth factor receptor 2. http://purl.obolibrary.org/obo/GO_0043209 myelin sheath http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. http://purl.obolibrary.org/obo/GO_0043229 intracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. http://purl.obolibrary.org/obo/GO_0043230 extracellular organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. http://purl.obolibrary.org/obo/GO_0043242 negative regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043243 positive regulation of protein-containing complex disassembly http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components. http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0043264 extracellular membraneless organelle http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. http://purl.obolibrary.org/obo/GO_0043362 nucleate erythrocyte maturation http://purl.obolibrary.org/obo/GO_0043249 erythrocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus. http://purl.obolibrary.org/obo/GO_0043363 nucleate erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0030218 erythrocyte differentiation The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds. http://purl.obolibrary.org/obo/GO_0043385 mycotoxin metabolic process http://purl.obolibrary.org/obo/GO_0009404 toxin metabolic process The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus. http://purl.obolibrary.org/obo/GO_0043386 mycotoxin biosynthetic process http://purl.obolibrary.org/obo/GO_0009403 toxin biosynthetic process The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus. http://purl.obolibrary.org/obo/GO_0043388 positive regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0043392 negative regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0043476 pigment accumulation http://purl.obolibrary.org/obo/GO_0043473 pigmentation The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus. http://purl.obolibrary.org/obo/GO_0043482 cellular pigment accumulation http://purl.obolibrary.org/obo/GO_0043476 pigment accumulation The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus. http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/GO_0043524 negative regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons. http://purl.obolibrary.org/obo/GO_0043525 positive regulation of neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process. http://purl.obolibrary.org/obo/GO_0043535 regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/GO_0043536 positive regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/GO_0043537 negative regulation of blood vessel endothelial cell migration http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. http://purl.obolibrary.org/obo/GO_0043576 regulation of respiratory gaseous exchange http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. http://purl.obolibrary.org/obo/GO_0043586 tongue development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. http://purl.obolibrary.org/obo/GO_0043587 tongue morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. http://purl.obolibrary.org/obo/GO_0043589 skin morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. http://purl.obolibrary.org/obo/GO_0043903 regulation of biological process involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association. http://purl.obolibrary.org/obo/GO_0043931 ossification involved in bone maturation http://purl.obolibrary.org/obo/GO_0001503 ossification The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. http://purl.obolibrary.org/obo/GO_0043932 ossification involved in bone remodeling http://purl.obolibrary.org/obo/GO_0001503 ossification The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli. http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/GO_0043938 positive regulation of sporulation http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/GO_0043939 negative regulation of sporulation http://purl.obolibrary.org/obo/GO_0043937 regulation of sporulation Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. http://purl.obolibrary.org/obo/GO_0043940 regulation of sexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0042173 regulation of sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis. http://purl.obolibrary.org/obo/GO_0043943 regulation of asexual sporulation resulting in formation of a cellular spore http://purl.obolibrary.org/obo/GO_0042173 regulation of sporulation resulting in formation of a cellular spore Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis. http://purl.obolibrary.org/obo/GO_0044001 migration in host http://purl.obolibrary.org/obo/GO_0051701 biological process involved in interaction with host The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044057 regulation of system process Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0044090 positive regulation of vacuole organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. http://purl.obolibrary.org/obo/GO_0044114 development of symbiont in host http://purl.obolibrary.org/obo/GO_0044111 formation of structure involved in a symbiotic process The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044127 regulation of development of symbiont in host http://purl.obolibrary.org/obo/GO_0044145 modulation of formation of structure involved in a symbiotic process Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044145 modulation of formation of structure involved in a symbiotic process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. http://purl.obolibrary.org/obo/GO_0044207 translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1990904 ribonucleoprotein complex A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator). http://purl.obolibrary.org/obo/GO_0044292 dendrite terminus http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole. http://purl.obolibrary.org/obo/GO_0044293 dendriole http://purl.obolibrary.org/obo/GO_0044292 dendrite terminus Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC). http://purl.obolibrary.org/obo/GO_0044297 cell body http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. http://purl.obolibrary.org/obo/GO_0044346 fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. http://purl.obolibrary.org/obo/GO_0044458 motile cilium assembly http://purl.obolibrary.org/obo/GO_0060271 cilium assembly The aggregation, arrangement and bonding together of a set of components to form a motile cilium. http://purl.obolibrary.org/obo/GO_0044565 dendritic cell proliferation http://purl.obolibrary.org/obo/GO_0032943 mononuclear cell proliferation The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/GO_0044566 chondrocyte activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_0045037 protein import into chloroplast stroma http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import. http://purl.obolibrary.org/obo/GO_0045124 regulation of bone resorption http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that modulates the frequency, rate or extent of bone tissue loss (resorption). http://purl.obolibrary.org/obo/GO_0045144 meiotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0000819 sister chromatid segregation The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0045179 apical cortex http://purl.obolibrary.org/obo/GO_0099738 cell cortex region The region that lies just beneath the plasma membrane on the apical edge of a cell. http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0007163 establishment or maintenance of cell polarity Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/GO_0045200 establishment of neuroblast polarity http://purl.obolibrary.org/obo/GO_0045196 establishment or maintenance of neuroblast polarity The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. http://purl.obolibrary.org/obo/GO_0045211 postsynaptic membrane http://purl.obolibrary.org/obo/GO_0097060 synaptic membrane A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0045296 cadherin binding http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding Binding to cadherin, a type I membrane protein involved in cell adhesion. http://purl.obolibrary.org/obo/GO_0045444 fat cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/GO_0045453 bone resorption http://purl.obolibrary.org/obo/GO_0001894 tissue homeostasis The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products. http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045599 negative regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045598 regulation of fat cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045600 positive regulation of fat cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0030856 regulation of epithelial cell differentiation Any process that modulates the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045602 negative regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045603 positive regulation of endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045601 regulation of endothelial cell differentiation Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. http://purl.obolibrary.org/obo/GO_0045604 regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that modulates the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045605 negative regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045606 positive regulation of epidermal cell differentiation http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. http://purl.obolibrary.org/obo/GO_0045647 negative regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045648 positive regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045653 negative regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045654 positive regulation of megakaryocyte differentiation http://purl.obolibrary.org/obo/GO_0045652 regulation of megakaryocyte differentiation Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation. http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045656 negative regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045657 positive regulation of monocyte differentiation http://purl.obolibrary.org/obo/GO_0045655 regulation of monocyte differentiation Any process that activates or increases the frequency, rate or extent of monocyte differentiation. http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045662 negative regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045661 regulation of myoblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045663 positive regulation of myoblast differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/GO_0045671 negative regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/GO_0045672 positive regulation of osteoclast differentiation http://purl.obolibrary.org/obo/GO_0045670 regulation of osteoclast differentiation Any process that activates or increases the frequency, rate or extent of osteoclast differentiation. http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045683 negative regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045684 positive regulation of epidermis development http://purl.obolibrary.org/obo/GO_0045682 regulation of epidermis development Any process that activates or increases the frequency, rate or extent of epidermis development. http://purl.obolibrary.org/obo/GO_0045724 positive regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of the formation of a cilium. http://purl.obolibrary.org/obo/GO_0045732 positive regulation of protein catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. http://purl.obolibrary.org/obo/GO_0045745 positive regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. http://purl.obolibrary.org/obo/GO_0045759 negative regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045760 positive regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0045766 positive regulation of angiogenesis http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis Any process that activates or increases angiogenesis. http://purl.obolibrary.org/obo/GO_0045769 negative regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045770 positive regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division Any process that activates or increases the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0045779 negative regulation of bone resorption http://purl.obolibrary.org/obo/GO_0046851 negative regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption. http://purl.obolibrary.org/obo/GO_0045780 positive regulation of bone resorption http://purl.obolibrary.org/obo/GO_0045124 regulation of bone resorption Any process that activates or increases the frequency, rate or extent of bone resorption. http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the rate or extent of progression through the cell cycle. http://purl.obolibrary.org/obo/GO_0045937 positive regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0046013 regulation of T cell homeostatic proliferation http://purl.obolibrary.org/obo/GO_0042129 regulation of T cell proliferation Any process that modulates the frequency, rate or extent of resting T cell proliferation. http://purl.obolibrary.org/obo/GO_0046532 regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046533 negative regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046534 positive regulation of photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0046621 negative regulation of organ growth http://purl.obolibrary.org/obo/GO_0048640 negative regulation of developmental growth Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046622 positive regulation of organ growth http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/GO_0046823 negative regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus. http://purl.obolibrary.org/obo/GO_0046824 positive regulation of nucleocytoplasmic transport http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm. http://purl.obolibrary.org/obo/GO_0046827 positive regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm. http://purl.obolibrary.org/obo/GO_0046849 bone remodeling http://purl.obolibrary.org/obo/GO_0048771 tissue remodeling The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis. http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0034103 regulation of tissue remodeling Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity. http://purl.obolibrary.org/obo/GO_0046851 negative regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling. http://purl.obolibrary.org/obo/GO_0046852 positive regulation of bone remodeling http://purl.obolibrary.org/obo/GO_0046850 regulation of bone remodeling Any process that activates or increases the frequency, rate or extent of bone remodeling. http://purl.obolibrary.org/obo/GO_0048102 autophagic cell death http://purl.obolibrary.org/obo/GO_0012501 programmed cell death A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells. http://purl.obolibrary.org/obo/GO_0048103 somatic stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line. http://purl.obolibrary.org/obo/GO_0048194 Golgi vesicle budding http://purl.obolibrary.org/obo/GO_0006900 vesicle budding from membrane The evagination of the Golgi membrane, resulting in formation of a vesicle. http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi http://purl.obolibrary.org/obo/GO_0006903 vesicle targeting The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. http://purl.obolibrary.org/obo/GO_0048639 positive regulation of developmental growth http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth Any process that activates, maintains or increases the rate of developmental growth. http://purl.obolibrary.org/obo/GO_0048770 pigment granule http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0048823 nucleate erythrocyte development http://purl.obolibrary.org/obo/GO_0048821 erythrocyte development The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis http://purl.obolibrary.org/obo/GO_0048514 blood vessel morphogenesis The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. http://purl.obolibrary.org/obo/GO_0050000 chromosome localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which a chromosome is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0050772 positive regulation of axonogenesis http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that activates or increases the frequency, rate or extent of axonogenesis. http://purl.obolibrary.org/obo/GO_0050840 extracellular matrix binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to a component of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation http://purl.obolibrary.org/obo/GO_0051249 regulation of lymphocyte activation Any process that modulates the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0050868 negative regulation of T cell activation http://purl.obolibrary.org/obo/GO_0050863 regulation of T cell activation Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of pigmented cell differentiation. http://purl.obolibrary.org/obo/GO_0050941 negative regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0050932 regulation of pigment cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0050942 positive regulation of pigment cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. http://purl.obolibrary.org/obo/GO_0051098 regulation of binding http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. http://purl.obolibrary.org/obo/GO_0051101 regulation of DNA binding http://purl.obolibrary.org/obo/GO_0051098 regulation of binding Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid). http://purl.obolibrary.org/obo/GO_0051145 smooth muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051148 negative regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051149 positive regulation of muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051338 regulation of transferase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system. http://purl.obolibrary.org/obo/GO_0051445 regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051446 positive regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051447 negative regulation of meiotic cell cycle http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. http://purl.obolibrary.org/obo/GO_0051469 vesicle fusion with vacuole http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. http://purl.obolibrary.org/obo/GO_0051654 establishment of mitochondrion localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of the mitochondrion to a specific location. http://purl.obolibrary.org/obo/GO_0051658 maintenance of nucleus location http://purl.obolibrary.org/obo/GO_0051647 nucleus localization Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0051704 multi-organism process http://purl.obolibrary.org/obo/GO_0008150 biological process A biological process which involves another organism of the same or different species. http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051930 regulation of sensory perception of pain http://purl.obolibrary.org/obo/GO_0051931 regulation of sensory perception Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. http://purl.obolibrary.org/obo/GO_0051969 regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0031644 regulation of nervous system process Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0055059 asymmetric neuroblast division http://purl.obolibrary.org/obo/GO_0055057 neuroblast division The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. http://purl.obolibrary.org/obo/GO_0060173 limb development http://purl.obolibrary.org/obo/GO_0048736 appendage development The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation http://purl.obolibrary.org/obo/GO_0001754 eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. http://purl.obolibrary.org/obo/GO_0060271 cilium assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0060348 bone development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. http://purl.obolibrary.org/obo/GO_0060465 pharynx development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0060581 cell fate commitment involved in pattern specification http://purl.obolibrary.org/obo/GO_0045165 cell fate commitment The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. http://purl.obolibrary.org/obo/GO_0060840 artery development http://purl.obolibrary.org/obo/GO_0001568 blood vessel development The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. http://purl.obolibrary.org/obo/GO_0061303 cornea development in camera-type eye http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. http://purl.obolibrary.org/obo/GO_0070977 bone maturation http://purl.obolibrary.org/obo/GO_0048799 animal organ maturation A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0071230 cellular response to amino acid stimulus http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0071383 cellular response to steroid hormone stimulus http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. http://purl.obolibrary.org/obo/GO_0071396 cellular response to lipid http://purl.obolibrary.org/obo/GO_0033993 response to lipid Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0071418 cellular response to amine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. http://purl.obolibrary.org/obo/GO_0071692 protein localization to extracellular region http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. http://purl.obolibrary.org/obo/GO_0071711 basement membrane organization http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. http://purl.obolibrary.org/obo/GO_0071867 response to monoamine http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0072537 fibroblast activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle http://purl.obolibrary.org/obo/GO_0032507 maintenance of protein location in cell Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. http://purl.obolibrary.org/obo/GO_0072596 establishment of protein localization to chloroplast http://purl.obolibrary.org/obo/GO_0072598 protein localization to chloroplast The directed movement of a protein to a specific location in a chloroplast. http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane http://purl.obolibrary.org/obo/GO_0051668 localization within membrane A process in which a protein is transported to, or maintained in, a specific location in a membrane. http://purl.obolibrary.org/obo/GO_0072659 protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. http://purl.obolibrary.org/obo/GO_0072697 protein localization to cell cortex http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery A process in which a protein is transported to, or maintained in, the cell cortex. http://purl.obolibrary.org/obo/GO_0072698 protein localization to microtubule cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. http://purl.obolibrary.org/obo/GO_0080154 regulation of fertilization http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). http://purl.obolibrary.org/obo/GO_0085030 symbiotic process benefiting host http://purl.obolibrary.org/obo/GO_0044403 biological process involved in symbiotic interaction A process carried out by symbiont gene products that enables a symbiotic interaction with a host organism, that is beneficial to the host organism. http://purl.obolibrary.org/obo/GO_0090151 establishment of protein localization to mitochondrial membrane http://purl.obolibrary.org/obo/GO_0090150 establishment of protein localization to membrane The directed movement of a protein to a specific location in the mitochondrial membrane. http://purl.obolibrary.org/obo/GO_0090162 establishment of epithelial cell polarity http://purl.obolibrary.org/obo/GO_0030010 establishment of cell polarity The specification and formation of anisotropic intracellular organization of an epithelial cell. http://purl.obolibrary.org/obo/GO_0090168 Golgi reassembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion http://purl.obolibrary.org/obo/GO_0002791 regulation of peptide secretion Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. http://purl.obolibrary.org/obo/GO_0090316 positive regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051222 positive regulation of protein transport Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090317 negative regulation of intracellular protein transport http://purl.obolibrary.org/obo/GO_0051224 negative regulation of protein transport Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. http://purl.obolibrary.org/obo/GO_0090435 protein localization to nuclear envelope http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. http://purl.obolibrary.org/obo/GO_0090497 mesenchymal cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. http://purl.obolibrary.org/obo/GO_0097355 protein localization to heterochromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin. http://purl.obolibrary.org/obo/GO_0097576 vacuole fusion http://purl.obolibrary.org/obo/GO_0048284 organelle fusion Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. http://purl.obolibrary.org/obo/GO_0098528 skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. http://purl.obolibrary.org/obo/GO_0098751 bone cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0098794 postsynapse http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The directed movement of a protein along a microtubule, mediated by motor proteins. http://purl.obolibrary.org/obo/GO_0099098 microtubule polymerization based movement http://purl.obolibrary.org/obo/GO_0007018 microtubule-based movement The movement of a cellular component as a result of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0099632 protein transport within plasma membrane http://purl.obolibrary.org/obo/GO_0032594 protein transport within lipid bilayer A process in which protein is transported from one region of the plasma membrane to another. http://purl.obolibrary.org/obo/GO_1900116 extracellular negative regulation of signal transduction http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction Any negative regulation of signal transduction that takes place in extracellular region. http://purl.obolibrary.org/obo/GO_1900180 regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1900181 negative regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1900182 positive regulation of protein localization to nucleus http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. http://purl.obolibrary.org/obo/GO_1901162 primary amino compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of primary amino compound. http://purl.obolibrary.org/obo/GO_1901338 catecholamine binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to catecholamine. http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_1901701 cellular response to oxygen-containing compound http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. http://purl.obolibrary.org/obo/GO_1902017 regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902913 positive regulation of neuroepithelial cell differentiation http://purl.obolibrary.org/obo/GO_0030858 positive regulation of epithelial cell differentiation Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation. http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton http://purl.obolibrary.org/obo/GO_0044380 protein localization to cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903225 negative regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_1903224 regulation of endodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903707 negative regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903708 positive regulation of hemopoiesis http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of hemopoiesis. http://purl.obolibrary.org/obo/GO_1903729 regulation of plasma membrane organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of plasma membrane organization. http://purl.obolibrary.org/obo/GO_1903778 protein localization to vacuolar membrane http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. http://purl.obolibrary.org/obo/GO_1904018 positive regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that activates or increases the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1905690 nucleus disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly The disaggregation of a nucleus into its constituent components. http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1905771 negative regulation of mesodermal cell differentiation http://purl.obolibrary.org/obo/GO_1905770 regulation of mesodermal cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1990778 protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, the cell periphery. http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000384 negative regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000542 negative regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/GO_2001028 positive regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0001508 action potential An action potential that occurs in a cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086015 SA node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a sinoatrial node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086016 AV node cell action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in an atrioventricular node cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086017 Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0086001 cardiac muscle cell action potential An action potential that occurs in a Purkinje myocyte. http://purl.obolibrary.org/obo/GO_0086018 SA node cell to atrial cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte. http://purl.obolibrary.org/obo/GO_0086019 cell-cell signaling involved in cardiac conduction http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium. http://purl.obolibrary.org/obo/GO_0086027 AV node cell to bundle of His cell signaling http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte. http://purl.obolibrary.org/obo/GO_0086029 Purkinje myocyte to ventricular cardiac muscle cell signaling http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell. http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction http://purl.obolibrary.org/obo/GO_0007154 cell communication Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086067 AV node cell to bundle of His cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086068 Purkinje myocyte to ventricular cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086070 SA node cell to atrial cardiac muscle cell communication http://purl.obolibrary.org/obo/GO_0086065 cell communication involved in cardiac conduction The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0086093 G protein-coupled acetylcholine receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0086103 G protein-coupled receptor signaling pathway involved in heart process A G protein-coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart. http://purl.obolibrary.org/obo/GO_0086103 G protein-coupled receptor signaling pathway involved in heart process http://purl.obolibrary.org/obo/GO_0007186 G protein-coupled receptor signaling pathway An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. http://purl.obolibrary.org/obo/GO_0089704 L-glutamate transmembrane export from vacuole http://purl.obolibrary.org/obo/GO_0032974 amino acid transmembrane export from vacuole The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0090025 regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0090026 positive regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that increases the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0090027 negative regulation of monocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that decreases the frequency, rate, or extent of monocyte chemotaxis. http://purl.obolibrary.org/obo/GO_0090063 positive regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044087 regulation of cellular component biogenesis Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090070 positive regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090071 negative regulation of ribosome biogenesis http://purl.obolibrary.org/obo/GO_0090069 regulation of ribosome biogenesis Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits. http://purl.obolibrary.org/obo/GO_0090091 positive regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0090138 regulation of actin cytoskeleton organization by cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. http://purl.obolibrary.org/obo/GO_0090139 mitochondrial chromosome packaging http://purl.obolibrary.org/obo/GO_0051276 chromosome organization A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_0090140 regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0090141 positive regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0090152 establishment of protein localization to mitochondrial membrane involved in mitochondrial fission http://purl.obolibrary.org/obo/GO_0090151 establishment of protein localization to mitochondrial membrane The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission. http://purl.obolibrary.org/obo/GO_0090160 Golgi to lysosome transport http://purl.obolibrary.org/obo/GO_0016482 cytosolic transport The directed movement of substances from the Golgi to lysosomes. http://purl.obolibrary.org/obo/GO_0090166 Golgi disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance. http://purl.obolibrary.org/obo/GO_0090170 regulation of Golgi inheritance http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0090258 negative regulation of mitochondrial fission http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments. http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0070663 regulation of leukocyte proliferation Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0090290 positive regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0090291 negative regulation of osteoclast proliferation http://purl.obolibrary.org/obo/GO_0090289 regulation of osteoclast proliferation Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. http://purl.obolibrary.org/obo/GO_0090299 regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090300 positive regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090301 negative regulation of neural crest formation http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0090454 glutamate transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport The directed movement of glutamate into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0090515 L-glutamate transmembrane import into vacuole http://purl.obolibrary.org/obo/GO_0090454 glutamate transmembrane import into vacuole The directed movement of L-glutamate into the vacuole across the vacuolar membrane. http://purl.obolibrary.org/obo/GO_0090685 RNA localization to nucleus http://purl.obolibrary.org/obo/GO_0006403 RNA localization A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus. http://purl.obolibrary.org/obo/GO_0097026 dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0097048 dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. http://purl.obolibrary.org/obo/GO_0097049 motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0097054 L-glutamate biosynthetic process http://purl.obolibrary.org/obo/GO_0006537 glutamate biosynthetic process The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid. http://purl.obolibrary.org/obo/GO_0097096 facial suture morphogenesis http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis The process in which any suture between facial bones is generated and organized. http://purl.obolibrary.org/obo/GO_0097104 postsynaptic membrane assembly http://purl.obolibrary.org/obo/GO_0071709 membrane assembly The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). http://purl.obolibrary.org/obo/GO_0097120 receptor localization to synapse http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. http://purl.obolibrary.org/obo/GO_0097152 mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0097177 mitochondrial ribosome binding http://purl.obolibrary.org/obo/GO_0043022 ribosome binding Binding to a mitochondrial ribosome. http://purl.obolibrary.org/obo/GO_0097212 lysosomal membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. http://purl.obolibrary.org/obo/GO_0097252 oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0034349 glial cell apoptotic process Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons. http://purl.obolibrary.org/obo/GO_0097386 glial cell projection http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A prolongation or process extending from a glial cell. http://purl.obolibrary.org/obo/GO_0097402 neuroblast migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure An arrangement of closely apposed microtubules running parallel to each other. http://purl.obolibrary.org/obo/GO_0097447 dendritic tree http://purl.obolibrary.org/obo/GO_0043005 neuron projection The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. http://purl.obolibrary.org/obo/GO_0097449 astrocyte projection http://purl.obolibrary.org/obo/GO_0097386 glial cell projection A prolongation or process extending from the soma of an astrocyte and wrapping around neurons. http://purl.obolibrary.org/obo/GO_0097454 Schwann cell microvillus http://purl.obolibrary.org/obo/GO_0097386 glial cell projection Small finger-like extension of a Schwann cell that contacts the nodal membrane. http://purl.obolibrary.org/obo/GO_0097473 retinal rod cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0097474 retinal cone cell apoptotic process http://purl.obolibrary.org/obo/GO_0051402 neuron apoptotic process Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina. http://purl.obolibrary.org/obo/GO_0097475 motor neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0097476 spinal cord motor neuron migration http://purl.obolibrary.org/obo/GO_0097475 motor neuron migration The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement. http://purl.obolibrary.org/obo/GO_0097511 dendritic cell dendrite http://purl.obolibrary.org/obo/GO_0120025 plasma membrane bounded cell projection A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. http://purl.obolibrary.org/obo/GO_0097512 cardiac myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/GO_0097534 lymphoid lineage cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage. http://purl.obolibrary.org/obo/GO_0097711 ciliary basal body-plasma membrane docking http://purl.obolibrary.org/obo/GO_0140056 organelle localization by membrane tethering The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. http://purl.obolibrary.org/obo/GO_0098523 neuromuscular junction of myotube http://purl.obolibrary.org/obo/GO_0031594 neuromuscular junction A neuromuscular junction in which the target muscle cell is a myotube. http://purl.obolibrary.org/obo/GO_0098544 maintenance of protein complex location http://purl.obolibrary.org/obo/GO_0051235 maintenance of location Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away. http://purl.obolibrary.org/obo/GO_0098545 maintenance of protein complex location in cytoplasm http://purl.obolibrary.org/obo/GO_0098544 maintenance of protein complex location Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0050839 cell adhesion molecule binding The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell. http://purl.obolibrary.org/obo/GO_0098632 cell-cell adhesion mediator activity http://purl.obolibrary.org/obo/GO_0098631 cell adhesion mediator activity The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell. http://purl.obolibrary.org/obo/GO_0098633 collagen fibril binding http://purl.obolibrary.org/obo/GO_0050840 extracellular matrix binding Binding to a collagen fibril. http://purl.obolibrary.org/obo/GO_0098635 protein complex involved in cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098636 protein complex involved in cell adhesion Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion. http://purl.obolibrary.org/obo/GO_0098641 cadherin binding involved in cell-cell adhesion http://purl.obolibrary.org/obo/GO_0098632 cell-cell adhesion mediator activity Any cadherin binding that occurs as part of the process of cell-cell adhesion. http://purl.obolibrary.org/obo/GO_0098644 complex of collagen trimers http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A complex of collagen trimers such as a fibril or collagen network. http://purl.obolibrary.org/obo/GO_0098666 G protein-coupled serotonin receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex that is capable of G protein-coupled serotonin receptor activity. http://purl.obolibrary.org/obo/GO_0098704 carbohydrate import across plasma membrane http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098712 L-glutamate import across plasma membrane http://purl.obolibrary.org/obo/GO_0089718 amino acid import across plasma membrane The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098723 skeletal muscle myofibril http://purl.obolibrary.org/obo/GO_0030016 myofibril A myofibril of a skeletal muscle fiber. http://purl.obolibrary.org/obo/GO_0098739 import across plasma membrane http://purl.obolibrary.org/obo/GO_0098657 import into cell The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol. http://purl.obolibrary.org/obo/GO_0098749 cerebellar neuron development http://purl.obolibrary.org/obo/GO_0021954 central nervous system neuron development The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0098867 intramembranous bone growth http://purl.obolibrary.org/obo/GO_0098868 bone growth The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. http://purl.obolibrary.org/obo/GO_0098871 postsynaptic actin cytoskeleton http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton The actin cytoskeleton that is part of a postsynapse. http://purl.obolibrary.org/obo/GO_0098877 neurotransmitter receptor transport to plasma membrane http://purl.obolibrary.org/obo/GO_0099637 neurotransmitter receptor transport The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. http://purl.obolibrary.org/obo/GO_0098883 synapse pruning http://purl.obolibrary.org/obo/GO_0050808 synapse organization A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared. http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098904 regulation of AV node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098906 regulation of Purkinje myocyte action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098907 regulation of SA node cell action potential http://purl.obolibrary.org/obo/GO_0098901 regulation of cardiac muscle cell action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098908 regulation of neuronal action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0098917 retrograde trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0098920 retrograde trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand. http://purl.obolibrary.org/obo/GO_0098926 postsynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a postsynapse. http://purl.obolibrary.org/obo/GO_0098928 presynaptic signal transduction http://purl.obolibrary.org/obo/GO_0007165 signal transduction Signal transduction in which the initial step occurs in a presynapse. http://purl.obolibrary.org/obo/GO_0098934 retrograde dendritic transport http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body. http://purl.obolibrary.org/obo/GO_0098935 dendritic transport http://purl.obolibrary.org/obo/GO_0008088 axo-dendritic transport The directed movement of organelles or molecules along microtubules in dendrites. http://purl.obolibrary.org/obo/GO_0098937 anterograde dendritic transport http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites. http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of mitochondria along microtubules in nerve cell dendrites. http://purl.obolibrary.org/obo/GO_0098957 anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0098958 retrograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0019896 axonal transport of mitochondrion The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse. http://purl.obolibrary.org/obo/GO_0098959 retrograde dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse. http://purl.obolibrary.org/obo/GO_0098960 postsynaptic neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0030594 neurotransmitter receptor activity Neurotransmitter receptor activity occurring in the postsynaptic membrane during synaptic transmission. http://purl.obolibrary.org/obo/GO_0098961 dendritic transport of ribonucleoprotein complex http://purl.obolibrary.org/obo/GO_0098935 dendritic transport The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites. http://purl.obolibrary.org/obo/GO_0098967 exocytic insertion of neurotransmitter receptor to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0099072 regulation of postsynaptic membrane neurotransmitter receptor levels The exocytic fusion of neurotransmitter receptor containing vesicles with the postsynaptic membrane resulting in the integration of NT receptors, enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion. http://purl.obolibrary.org/obo/GO_0098969 neurotransmitter receptor transport to postsynaptic membrane http://purl.obolibrary.org/obo/GO_1903540 establishment of protein localization to postsynaptic membrane The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles. http://purl.obolibrary.org/obo/GO_0098971 anterograde dendritic transport of neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0098937 anterograde dendritic transport The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse. http://purl.obolibrary.org/obo/GO_0098972 anterograde dendritic transport of mitochondrion http://purl.obolibrary.org/obo/GO_0098939 dendritic transport of mitochondrion The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body. http://purl.obolibrary.org/obo/GO_0098974 postsynaptic actin cytoskeleton organization http://purl.obolibrary.org/obo/GO_0099188 postsynaptic cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton. http://purl.obolibrary.org/obo/GO_0098975 postsynapse of neuromuscular junction http://purl.obolibrary.org/obo/GO_0098794 postsynapse The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma. http://purl.obolibrary.org/obo/GO_0098978 glutamatergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses glutamate as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0098981 cholinergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses acetylcholine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0098982 GABA-ergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory. http://purl.obolibrary.org/obo/GO_0098992 neuronal dense core vesicle http://purl.obolibrary.org/obo/GO_0031045 dense core granule A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals. http://purl.obolibrary.org/obo/GO_0099012 neuronal dense core vesicle membrane http://purl.obolibrary.org/obo/GO_0032127 dense core granule membrane The lipid bilayer surrounding a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0099014 neuronal dense core vesicle organization http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle. http://purl.obolibrary.org/obo/GO_0099054 presynapse assembly http://purl.obolibrary.org/obo/GO_0099172 presynapse organization The aggregation, arrangement and bonding together of a set of components to form a presynapse. http://purl.obolibrary.org/obo/GO_0099068 postsynapse assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a postsynapse. http://purl.obolibrary.org/obo/GO_0099072 regulation of postsynaptic membrane neurotransmitter receptor levels http://purl.obolibrary.org/obo/GO_0065008 regulation of biological quality Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic membrane. http://purl.obolibrary.org/obo/GO_0099074 mitochondrion to lysosome vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0099075 mitochondrion-derived vesicle mediated transport Vesicle-mediated transport of cargo from the mitochondrion to the lysosome, mediated by a mitochondrion-derived vesicle. http://purl.obolibrary.org/obo/GO_0099075 mitochondrion-derived vesicle mediated transport http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Vesicle-mediated transport of cargo from the mitochondrion by a mitochondrion-derived vesicle. http://purl.obolibrary.org/obo/GO_0099081 supramolecular polymer http://purl.obolibrary.org/obo/GO_0099080 supramolecular complex A polymeric supramolecular structure. http://purl.obolibrary.org/obo/GO_0099082 retrograde trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099083 retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission Modulation of synaptic transmission by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide. http://purl.obolibrary.org/obo/GO_0099112 microtubule polymerization based protein transport http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport The transport of a protein driven by polymerization of a microtubule to which it is attached. http://purl.obolibrary.org/obo/GO_0099118 microtubule-based protein transport http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport A microtubule-based process that results in the transport of proteins. http://purl.obolibrary.org/obo/GO_0099123 somato-dendritic dopamine secretion http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron. http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport http://purl.obolibrary.org/obo/GO_1901950 dense core granule transport The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments. http://purl.obolibrary.org/obo/GO_0099522 cytosolic region http://purl.obolibrary.org/obo/GO_0005829 cytosol Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol. http://purl.obolibrary.org/obo/GO_0099523 presynaptic cytosol http://purl.obolibrary.org/obo/GO_0099522 cytosolic region The region of the cytosol consisting of all cytosol that is part of the presynapse. http://purl.obolibrary.org/obo/GO_0099524 postsynaptic cytosol http://purl.obolibrary.org/obo/GO_0099522 cytosolic region The region of the cytosol consisting of all cytosol that is part of the postsynapse. http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling to, from or within a synapse. http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling in either direction across the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide http://purl.obolibrary.org/obo/GO_0099536 synaptic signaling Cell-cell signaling to or from a synapse, mediated by a peptide. http://purl.obolibrary.org/obo/GO_0099540 trans-synaptic signaling by neuropeptide http://purl.obolibrary.org/obo/GO_0099538 synaptic signaling via neuropeptide Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft. http://purl.obolibrary.org/obo/GO_0099541 trans-synaptic signaling by lipid http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid. http://purl.obolibrary.org/obo/GO_0099546 protein catabolic process, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140246 protein catabolic process at synapse Any protein degradation process, occurring at a presynapse, that regulates synaptic transmission. http://purl.obolibrary.org/obo/GO_0099547 regulation of translation at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the synapse. http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099537 trans-synaptic signaling Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099551 trans-synaptic signaling by neuropeptide, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099552 trans-synaptic signaling by lipid, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099550 trans-synaptic signaling, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. http://purl.obolibrary.org/obo/GO_0099571 postsynaptic cytoskeleton http://purl.obolibrary.org/obo/GO_0005856 cytoskeleton The portion of the cytoskeleton contained within the postsynapse. http://purl.obolibrary.org/obo/GO_0099574 regulation of protein catabolic process at synapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating protein degradation at the synapse. http://purl.obolibrary.org/obo/GO_0099575 regulation of protein catabolic process at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse. http://purl.obolibrary.org/obo/GO_0099576 regulation of protein catabolic process at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse. http://purl.obolibrary.org/obo/GO_0099577 regulation of translation at presynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse Any process that modulates synaptic transmission by regulating translation occurring at the presynapse. http://purl.obolibrary.org/obo/GO_0099578 regulation of translation at postsynapse, modulating synaptic transmission http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse. http://purl.obolibrary.org/obo/GO_0099601 regulation of neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0010469 regulation of signaling receptor activity Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector function such as ion selectivity or pore opening/closing in ionotropic receptors. http://purl.obolibrary.org/obo/GO_0099637 neurotransmitter receptor transport http://purl.obolibrary.org/obo/GO_0031503 protein-containing complex localization The directed movement of neurotransmitter receptors. http://purl.obolibrary.org/obo/GO_0099640 axo-dendritic protein transport http://purl.obolibrary.org/obo/GO_0098840 protein transport along microtubule The directed movement of proteins along microtubules in neuron projections. http://purl.obolibrary.org/obo/GO_0099641 anterograde axonal protein transport http://purl.obolibrary.org/obo/GO_1905383 protein localization to presynapse The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons. http://purl.obolibrary.org/obo/GO_0099642 retrograde axonal protein transport http://purl.obolibrary.org/obo/GO_0099640 axo-dendritic protein transport The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons. http://purl.obolibrary.org/obo/GO_0101023 vascular endothelial cell proliferation http://purl.obolibrary.org/obo/GO_0001935 endothelial cell proliferation The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0101024 mitotic nuclear membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A mitotic cell cycle process which results in the assembly, arrangement, or disassembly of the nuclear inner or outer membrane during mitosis. http://purl.obolibrary.org/obo/GO_0101025 nuclear membrane biogenesis http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis The process in which a nuclear membrane is synthesized, aggregates, and bonds together. http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_0001817 regulation of cytokine production Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_1900016 negative regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_1900017 positive regulation of cytokine production involved in inflammatory response http://purl.obolibrary.org/obo/GO_1900015 regulation of cytokine production involved in inflammatory response Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response. http://purl.obolibrary.org/obo/GO_1900115 extracellular regulation of signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any regulation of signal transduction that takes place in the extracellular region. http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900118 negative regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_1900117 regulation of execution phase of apoptosis Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900119 positive regulation of execution phase of apoptosis http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis. http://purl.obolibrary.org/obo/GO_1900125 regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900126 negative regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900127 positive regulation of hyaluronan biosynthetic process http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. http://purl.obolibrary.org/obo/GO_1900131 negative regulation of lipid binding http://purl.obolibrary.org/obo/GO_0051100 negative regulation of binding Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding. http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0034350 regulation of glial cell apoptotic process Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1900142 negative regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1900143 positive regulation of oligodendrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1900141 regulation of oligodendrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that modulates the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_1900148 negative regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1900147 regulation of Schwann cell migration Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_1900149 positive regulation of Schwann cell migration http://purl.obolibrary.org/obo/GO_1903977 positive regulation of glial cell migration Any process that activates or increases the frequency, rate or extent of Schwann cell migration. http://purl.obolibrary.org/obo/GO_1900160 plastid chromosome packaging http://purl.obolibrary.org/obo/GO_0051276 chromosome organization A process in which plastidial DNA and associated proteins organize into a compact, orderly structure. http://purl.obolibrary.org/obo/GO_1900193 regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900194 negative regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900195 positive regulation of oocyte maturation http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of oocyte maturation. http://purl.obolibrary.org/obo/GO_1900247 regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_0006448 regulation of translational elongation Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_1900248 negative regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_2000766 negative regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_1900249 positive regulation of cytoplasmic translational elongation http://purl.obolibrary.org/obo/GO_1900247 regulation of cytoplasmic translational elongation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation. http://purl.obolibrary.org/obo/GO_1900366 negative regulation of defense response to insect http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_1900367 positive regulation of defense response to insect http://purl.obolibrary.org/obo/GO_2000068 regulation of defense response to insect Any process that activates or increases the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_1900407 regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_1900408 negative regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_1900409 positive regulation of cellular response to oxidative stress http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress. http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_1900450 negative regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_1900451 positive regulation of glutamate receptor signaling pathway http://purl.obolibrary.org/obo/GO_1900449 regulation of glutamate receptor signaling pathway Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway. http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane Any process that modulates the frequency, rate or extent of glycine import into a cell. http://purl.obolibrary.org/obo/GO_1900924 negative regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane Any process that stops, prevents or reduces the frequency, rate or extent of glycine import into a cell. http://purl.obolibrary.org/obo/GO_1900925 positive regulation of glycine import across plasma membrane http://purl.obolibrary.org/obo/GO_1900923 regulation of glycine import across plasma membrane Any process that activates or increases the frequency, rate or extent of glycine import. http://purl.obolibrary.org/obo/GO_1901031 regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that modulates the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_1901032 negative regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_1901033 positive regulation of response to reactive oxygen species http://purl.obolibrary.org/obo/GO_1902884 positive regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species. http://purl.obolibrary.org/obo/GO_1901148 gene expression involved in extracellular matrix organization http://purl.obolibrary.org/obo/GO_0010467 gene expression Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_1901163 regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_1901164 negative regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_1901165 positive regulation of trophoblast cell migration http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. http://purl.obolibrary.org/obo/GO_1901166 neural crest cell migration involved in autonomic nervous system development http://purl.obolibrary.org/obo/GO_0001755 neural crest cell migration Any neural crest cell migration that is involved in autonomic nervous system development. http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901191 negative regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901192 positive regulation of formation of translation initiation ternary complex http://purl.obolibrary.org/obo/GO_1901190 regulation of formation of translation initiation ternary complex Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex. http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901202 negative regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_1901201 regulation of extracellular matrix assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901203 positive regulation of extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901211 negative regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901210 regulation of cardiac chamber formation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901212 positive regulation of cardiac chamber formation http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_2000826 regulation of heart morphogenesis Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901220 negative regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901221 positive regulation of cardiac chamber morphogenesis http://purl.obolibrary.org/obo/GO_1901219 regulation of cardiac chamber morphogenesis Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0051052 regulation of DNA metabolic process Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901859 negative regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_1901858 regulation of mitochondrial DNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901860 positive regulation of mitochondrial DNA metabolic process http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process. http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of cell junction assembly. http://purl.obolibrary.org/obo/GO_1901950 dense core granule transport http://purl.obolibrary.org/obo/GO_0032253 dense core granule localization The directed movement a dense core granule within a cell. http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_1902883 negative regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_1902884 positive regulation of response to oxidative stress http://purl.obolibrary.org/obo/GO_1902882 regulation of response to oxidative stress Any process that activates or increases the frequency, rate or extent of response to oxidative stress. http://purl.obolibrary.org/obo/GO_1903011 negative regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that stops, prevents or reduces the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903012 positive regulation of bone development http://purl.obolibrary.org/obo/GO_1903010 regulation of bone development Any process that activates or increases the frequency, rate or extent of bone development. http://purl.obolibrary.org/obo/GO_1903076 regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903077 negative regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903078 positive regulation of protein localization to plasma membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. http://purl.obolibrary.org/obo/GO_1903327 negative regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903336 negative regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903337 positive regulation of vacuolar transport http://purl.obolibrary.org/obo/GO_1903335 regulation of vacuolar transport Any process that activates or increases the frequency, rate or extent of vacuolar transport. http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of Golgi organization. http://purl.obolibrary.org/obo/GO_1903441 protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. http://purl.obolibrary.org/obo/GO_1903539 protein localization to postsynaptic membrane http://purl.obolibrary.org/obo/GO_0062237 protein localization to postsynapse A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane. http://purl.obolibrary.org/obo/GO_1903540 establishment of protein localization to postsynaptic membrane http://purl.obolibrary.org/obo/GO_1903539 protein localization to postsynaptic membrane The directed movement of a protein to a specific location in a postsynaptic membrane. http://purl.obolibrary.org/obo/GO_1903747 regulation of establishment of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_1903749 positive regulation of establishment of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_1903747 regulation of establishment of protein localization to mitochondrion Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903829 positive regulation of protein localization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_1903977 positive regulation of glial cell migration http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that activates or increases the frequency, rate or extent of glial cell migration. http://purl.obolibrary.org/obo/GO_1904587 response to glycoprotein http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_1904689 negative regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_1904690 positive regulation of cytoplasmic translational initiation http://purl.obolibrary.org/obo/GO_1904688 regulation of cytoplasmic translational initiation Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation. http://purl.obolibrary.org/obo/GO_1904970 brush border assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border. http://purl.obolibrary.org/obo/GO_1905038 regulation of membrane lipid metabolic process http://purl.obolibrary.org/obo/GO_0019216 regulation of lipid metabolic process Any process that modulates the frequency, rate or extent of membrane lipid metabolic process. http://purl.obolibrary.org/obo/GO_1905383 protein localization to presynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse A process in which a protein is transported to, or maintained in, a location within a presynapse. http://purl.obolibrary.org/obo/GO_1905475 regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1905476 negative regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1905477 positive regulation of protein localization to membrane http://purl.obolibrary.org/obo/GO_1905475 regulation of protein localization to membrane Any process that activates or increases the frequency, rate or extent of protein localization to membrane. http://purl.obolibrary.org/obo/GO_1990182 exosomal secretion http://purl.obolibrary.org/obo/GO_0051650 establishment of vesicle localization The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_2000068 regulation of defense response to insect http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response Any process that modulates the frequency, rate or extent of defense response to insect. http://purl.obolibrary.org/obo/GO_2000282 regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000283 negative regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of an amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000284 positive regulation of amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000381 negative regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000382 positive regulation of mesoderm development http://purl.obolibrary.org/obo/GO_2000380 regulation of mesoderm development Any process that activates or increases the frequency, rate or extent of mesoderm development. http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_2000766 negative regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_2000767 positive regulation of cytoplasmic translation http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of cytoplasmic translation. http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001234 negative regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_2001233 regulation of apoptotic signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_2001235 positive regulation of apoptotic signaling pathway http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway. http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1905330 regulation of morphogenesis of an epithelium Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901533 negative regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901534 positive regulation of hematopoietic progenitor cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation. http://purl.obolibrary.org/obo/GO_1901550 regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901551 negative regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901552 positive regulation of endothelial cell development http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of endothelial cell development. http://purl.obolibrary.org/obo/GO_1901588 dendritic microtubule http://purl.obolibrary.org/obo/GO_0005874 microtubule Any microtubule in a dendrite, a neuron projection. http://purl.obolibrary.org/obo/GO_1901589 axon microtubule bundle http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment. http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901609 negative regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901610 positive regulation of vesicle transport along microtubule http://purl.obolibrary.org/obo/GO_1901608 regulation of vesicle transport along microtubule Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. http://purl.obolibrary.org/obo/GO_1901624 negative regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/GO_1901626 regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_1901627 negative regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_1901628 positive regulation of postsynaptic membrane organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization. http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901693 negative regulation of compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1901692 regulation of compound eye retinal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process. http://purl.obolibrary.org/obo/GO_1901706 mesenchymal cell differentiation involved in bone development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. http://purl.obolibrary.org/obo/GO_1901715 regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_1901716 negative regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_1901717 positive regulation of gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process. http://purl.obolibrary.org/obo/GO_1901951 regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that modulates the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901952 negative regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904810 negative regulation of dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901953 positive regulation of anterograde dense core granule transport http://purl.obolibrary.org/obo/GO_1904811 positive regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901954 regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that modulates the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901955 negative regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001018 negative regulation of retrograde axon cargo transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901956 positive regulation of retrograde dense core granule transport http://purl.obolibrary.org/obo/GO_2001019 positive regulation of retrograde axon cargo transport Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport. http://purl.obolibrary.org/obo/GO_1901964 positive regulation of cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1901963 regulation of cell proliferation involved in outflow tract morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902018 negative regulation of cilium assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. http://purl.obolibrary.org/obo/GO_1902020 negative regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902034 negative regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902035 positive regulation of hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_1902033 regulation of hematopoietic stem cell proliferation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation. http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1901532 regulation of hematopoietic progenitor cell differentiation Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902037 negative regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902038 positive regulation of hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_1902036 regulation of hematopoietic stem cell differentiation Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation. http://purl.obolibrary.org/obo/GO_1902065 response to L-glutamate http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus. http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_0001959 regulation of cytokine-mediated signaling pathway Any process that modulates the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_1902212 negative regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_1902213 positive regulation of prolactin signaling pathway http://purl.obolibrary.org/obo/GO_1902211 regulation of prolactin signaling pathway Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway. http://purl.obolibrary.org/obo/GO_1902217 erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033028 myeloid cell apoptotic process Any apoptotic process in an erythrocyte. http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_0033032 regulation of myeloid cell apoptotic process Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902251 negative regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902252 positive regulation of erythrocyte apoptotic process http://purl.obolibrary.org/obo/GO_1902250 regulation of erythrocyte apoptotic process Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process. http://purl.obolibrary.org/obo/GO_1902256 regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902257 negative regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902258 positive regulation of apoptotic process involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_1902339 positive regulation of apoptotic process involved in morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902262 apoptotic process involved in blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0060561 apoptotic process involved in morphogenesis Any apoptotic process that is involved in blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_1902340 negative regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1902396 protein localization to bicellular tight junction http://purl.obolibrary.org/obo/GO_0150105 protein localization to cell-cell junction A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. http://purl.obolibrary.org/obo/GO_1902463 protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a cell leading edge. http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_1902474 positive regulation of protein localization to synapse http://purl.obolibrary.org/obo/GO_1902473 regulation of protein localization to synapse Any process that activates or increases the frequency, rate or extent of protein localization to synapse. http://purl.obolibrary.org/obo/GO_1902510 regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903624 regulation of DNA catabolic process Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1902511 negative regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903625 negative regulation of DNA catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1902512 positive regulation of apoptotic DNA fragmentation http://purl.obolibrary.org/obo/GO_1903626 positive regulation of DNA catabolic process Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation. http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of organelle transport along microtubule. http://purl.obolibrary.org/obo/GO_1902570 protein localization to nucleolus http://purl.obolibrary.org/obo/GO_0034504 protein localization to nucleus A process in which a protein is transported to, or maintained in, a location within a nucleolus. http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1902684 negative regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1902685 positive regulation of receptor localization to synapse http://purl.obolibrary.org/obo/GO_1902683 regulation of receptor localization to synapse Any process that activates or increases the frequency, rate or extent of receptor localization to synapse. http://purl.obolibrary.org/obo/GO_1902710 GABA receptor complex http://purl.obolibrary.org/obo/GO_0043235 receptor complex A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor. http://purl.obolibrary.org/obo/GO_1902721 negative regulation of prolactin secretion http://purl.obolibrary.org/obo/GO_0090278 negative regulation of peptide hormone secretion Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion. http://purl.obolibrary.org/obo/GO_1902722 positive regulation of prolactin secretion http://purl.obolibrary.org/obo/GO_0090277 positive regulation of peptide hormone secretion Any process that activates or increases the frequency, rate or extent of prolactin secretion. http://purl.obolibrary.org/obo/GO_1902738 regulation of chondrocyte differentiation involved in endochondral bone morphogenesis http://purl.obolibrary.org/obo/GO_0032330 regulation of chondrocyte differentiation Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. http://purl.obolibrary.org/obo/GO_1902761 positive regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that activates or increases the frequency, rate or extent of chondrocyte development. http://purl.obolibrary.org/obo/GO_1902809 regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902810 negative regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902811 positive regulation of skeletal muscle fiber differentiation http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. http://purl.obolibrary.org/obo/GO_1902816 regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1902817 negative regulation of protein localization to microtubule http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902839 negative regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902840 positive regulation of nuclear migration along microtubule http://purl.obolibrary.org/obo/GO_1902838 regulation of nuclear migration along microtubule Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902864 negative regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1902865 positive regulation of embryonic camera-type eye development http://purl.obolibrary.org/obo/GO_1902863 regulation of embryonic camera-type eye development Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. http://purl.obolibrary.org/obo/GO_1903045 neural crest cell migration involved in sympathetic nervous system development http://purl.obolibrary.org/obo/GO_1901166 neural crest cell migration involved in autonomic nervous system development Any neural crest cell migration that is involved in sympathetic nervous system development. http://purl.obolibrary.org/obo/GO_1903116 positive regulation of actin filament-based movement http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of actin filament-based movement. http://purl.obolibrary.org/obo/GO_1903120 protein localization to actin filament bundle http://purl.obolibrary.org/obo/GO_1903119 protein localization to actin cytoskeleton A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. http://purl.obolibrary.org/obo/GO_1903179 regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903180 negative regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903181 positive regulation of dopamine biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process. http://purl.obolibrary.org/obo/GO_1903226 positive regulation of endodermal cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. http://purl.obolibrary.org/obo/GO_1903292 protein localization to Golgi membrane http://purl.obolibrary.org/obo/GO_0072657 protein localization to membrane A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. http://purl.obolibrary.org/obo/GO_1903294 regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1903295 negative regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051967 negative regulation of synaptic transmission, glutamatergic Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission. http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_0051252 regulation of RNA metabolic process Any process that modulates the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903328 positive regulation of tRNA metabolic process http://purl.obolibrary.org/obo/GO_1903326 regulation of tRNA metabolic process Any process that activates or increases the frequency, rate or extent of tRNA metabolic process. http://purl.obolibrary.org/obo/GO_1903347 negative regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_1903348 positive regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly Any process that activates or increases the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_1903350 response to dopamine http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. http://purl.obolibrary.org/obo/GO_1903351 cellular response to dopamine http://purl.obolibrary.org/obo/GO_0071870 cellular response to catecholamine stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. http://purl.obolibrary.org/obo/GO_1903379 regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that modulates the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903380 positive regulation of mitotic chromosome condensation http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation. http://purl.obolibrary.org/obo/GO_1903537 meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_1903046 meiotic cell cycle process Any meiotic cell cycle process that is involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903538 regulation of meiotic cell cycle process involved in oocyte maturation http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0017157 regulation of exocytosis Any process that modulates the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903542 negative regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_1903541 regulation of exosomal secretion Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903543 positive regulation of exosomal secretion http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis Any process that activates or increases the frequency, rate or extent of exosomal secretion. http://purl.obolibrary.org/obo/GO_1903551 regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903552 negative regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903553 positive regulation of extracellular exosome assembly http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly. http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903565 negative regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903566 positive regulation of protein localization to cilium http://purl.obolibrary.org/obo/GO_1903564 regulation of protein localization to cilium Any process that activates or increases the frequency, rate or extent of protein localization to cilium. http://purl.obolibrary.org/obo/GO_1903567 regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903568 negative regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903569 positive regulation of protein localization to ciliary membrane http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. http://purl.obolibrary.org/obo/GO_1903624 regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1903625 negative regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1903626 positive regulation of DNA catabolic process http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process Any process that activates or increases the frequency, rate or extent of DNA catabolic process. http://purl.obolibrary.org/obo/GO_1903748 negative regulation of establishment of protein localization to mitochondrion http://purl.obolibrary.org/obo/GO_1903747 regulation of establishment of protein localization to mitochondrion Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion. http://purl.obolibrary.org/obo/GO_1903780 negative regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1903781 positive regulation of cardiac conduction http://purl.obolibrary.org/obo/GO_1903779 regulation of cardiac conduction Any process that activates or increases the frequency, rate or extent of cardiac conduction. http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904036 negative regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_1904035 regulation of epithelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904037 positive regulation of epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904376 negative regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904377 positive regulation of protein localization to cell periphery http://purl.obolibrary.org/obo/GO_1904375 regulation of protein localization to cell periphery Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. http://purl.obolibrary.org/obo/GO_1904491 protein localization to ciliary transition zone http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1904810 negative regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1904811 positive regulation of dense core granule transport http://purl.obolibrary.org/obo/GO_1904809 regulation of dense core granule transport Any process that activates or increases the frequency, rate or extent of dense core granule transport. http://purl.obolibrary.org/obo/GO_1905216 positive regulation of RNA binding http://purl.obolibrary.org/obo/GO_0051099 positive regulation of binding Any process that activates or increases the frequency, rate or extent of RNA binding. http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_2001222 regulation of neuron migration Any process that modulates the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1905484 negative regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1905485 positive regulation of motor neuron migration http://purl.obolibrary.org/obo/GO_1905483 regulation of motor neuron migration Any process that activates or increases the frequency, rate or extent of motor neuron migration. http://purl.obolibrary.org/obo/GO_1905755 protein localization to cytoplasmic microtubule http://purl.obolibrary.org/obo/GO_0035372 protein localization to microtubule A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. http://purl.obolibrary.org/obo/GO_1905821 positive regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation Any process that activates or increases the frequency, rate or extent of chromosome condensation. http://purl.obolibrary.org/obo/GO_1990010 compound eye retinal cell apoptotic process http://purl.obolibrary.org/obo/GO_1990009 retinal cell apoptotic process Any apoptotic process in a compound eye retinal cell. http://purl.obolibrary.org/obo/GO_1990048 anterograde neuronal dense core vesicle transport http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse. http://purl.obolibrary.org/obo/GO_1990049 retrograde neuronal dense core vesicle transport http://purl.obolibrary.org/obo/GO_0099519 dense core granule cytoskeletal transport The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body. http://purl.obolibrary.org/obo/GO_1990239 steroid hormone binding http://purl.obolibrary.org/obo/GO_0042562 hormone binding Binding to a steroid hormone. http://purl.obolibrary.org/obo/GO_2000211 regulation of glutamate metabolic process http://purl.obolibrary.org/obo/GO_0006521 regulation of amino acid metabolic process Any process that modulates the frequency, rate or extent of glutamate metabolic process. http://purl.obolibrary.org/obo/GO_2000212 negative regulation of glutamate metabolic process http://purl.obolibrary.org/obo/GO_2000211 regulation of glutamate metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process. http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_2000402 negative regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_2000785 regulation of autophagosome assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that modulates the frequency, rate or extent of autophagosome assembly. http://purl.obolibrary.org/obo/GO_2000810 regulation of bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly Any process that modulates the frequency, rate or extent of tight junction assembly. http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001015 negative regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001014 regulation of skeletal muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001016 positive regulation of skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_0032386 regulation of intracellular transport Any process that modulates the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_2001018 negative regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_2001019 positive regulation of retrograde axon cargo transport http://purl.obolibrary.org/obo/GO_2001017 regulation of retrograde axon cargo transport Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport. http://purl.obolibrary.org/obo/GO_1905632 protein localization to euchromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin A process in which a protein is transported to, or maintained in, a location within an euchromatin. http://purl.obolibrary.org/obo/GO_1905633 establishment of protein localization to euchromatin http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localization to chromatin The directed movement of a protein to a specific location in an euchromatin. http://purl.obolibrary.org/obo/GO_1905671 regulation of lysosome organization http://purl.obolibrary.org/obo/GO_0044088 regulation of vacuole organization Any process that modulates the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1905672 negative regulation of lysosome organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1905673 positive regulation of lysosome organization http://purl.obolibrary.org/obo/GO_1905671 regulation of lysosome organization Any process that activates or increases the frequency, rate or extent of lysosome organization. http://purl.obolibrary.org/obo/GO_1905720 cytoplasmic microtubule bundle http://purl.obolibrary.org/obo/GO_0097427 microtubule bundle Any microtubule bundle that is part of a cytoplasm. http://purl.obolibrary.org/obo/GO_1905806 regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905807 negative regulation of synapse pruning http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905808 positive regulation of synapse pruning http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of synapse pruning. http://purl.obolibrary.org/obo/GO_1905833 negative regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. http://purl.obolibrary.org/obo/GO_1905864 regulation of Atg1/ULK1 kinase complex assembly http://purl.obolibrary.org/obo/GO_0043254 regulation of protein-containing complex assembly Any process that modulates the frequency, rate or extent of Atg1/ULK1 kinase complex assembly. http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905872 negative regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905873 positive regulation of protein localization to cell leading edge http://purl.obolibrary.org/obo/GO_1905871 regulation of protein localization to cell leading edge Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905900 negative regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905901 positive regulation of smooth muscle tissue development http://purl.obolibrary.org/obo/GO_1905899 regulation of smooth muscle tissue development Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905903 negative regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905904 positive regulation of mesoderm formation http://purl.obolibrary.org/obo/GO_1905902 regulation of mesoderm formation Any process that activates or increases the frequency, rate or extent of mesoderm formation. http://purl.obolibrary.org/obo/GO_1905921 regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that modulates the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905922 negative regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905923 positive regulation of acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process Any process that activates or increases the frequency, rate or extent of acetylcholine biosynthetic process. http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905937 negative regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905938 positive regulation of germ cell proliferation http://purl.obolibrary.org/obo/GO_1905936 regulation of germ cell proliferation Any process that activates or increases the frequency, rate or extent of germ cell proliferation. http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that modulates the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905940 negative regulation of gonad development http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1905941 positive regulation of gonad development http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of gonad development. http://purl.obolibrary.org/obo/GO_1990280 RNA localization to chromatin http://purl.obolibrary.org/obo/GO_0006403 RNA localization A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_1990497 regulation of cytoplasmic translation in response to stress http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_1990502 dense core granule maturation http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis. http://purl.obolibrary.org/obo/GO_1990580 regulation of cytoplasmic translational termination http://purl.obolibrary.org/obo/GO_2000765 regulation of cytoplasmic translation Any process that modulates the frequency, rate or extent of cytoplasmic translational termination. http://purl.obolibrary.org/obo/GO_1990611 regulation of cytoplasmic translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_1990625 negative regulation of cytoplasmic translational initiation in response to stress http://purl.obolibrary.org/obo/GO_1990611 regulation of cytoplasmic translational initiation in response to stress Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_1990849 vacuolar localization http://purl.obolibrary.org/obo/GO_0051640 organelle localization Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. http://purl.obolibrary.org/obo/GO_1990917 ooplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of an ovum. http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_2000110 negative regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_2000111 positive regulation of macrophage apoptotic process http://purl.obolibrary.org/obo/GO_2000109 regulation of macrophage apoptotic process Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process. http://purl.obolibrary.org/obo/GO_2000155 positive regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_2000173 negative regulation of branching morphogenesis of a nerve http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_0045580 regulation of T cell differentiation Any process that modulates the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_2000175 negative regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_2000176 positive regulation of pro-T cell differentiation http://purl.obolibrary.org/obo/GO_2000174 regulation of pro-T cell differentiation Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation. http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development http://purl.obolibrary.org/obo/GO_1905939 regulation of gonad development Any process that modulates the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000195 negative regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000196 positive regulation of female gonad development http://purl.obolibrary.org/obo/GO_2000194 regulation of female gonad development Any process that activates or increases the frequency, rate or extent of female gonad development. http://purl.obolibrary.org/obo/GO_2000198 negative regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_2000199 positive regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization Any process that modulates the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_2000239 negative regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_2000240 positive regulation of tRNA export from nucleus http://purl.obolibrary.org/obo/GO_2000238 regulation of tRNA export from nucleus Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus. http://purl.obolibrary.org/obo/GO_2000248 negative regulation of establishment or maintenance of neuroblast polarity http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000270 negative regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_2000269 regulation of fibroblast apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000271 positive regulation of fibroblast apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process. http://purl.obolibrary.org/obo/GO_2000287 positive regulation of myotome development http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development Any process that activates or increases the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_2000288 positive regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that activates or increases the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000290 regulation of myotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of myotome development. http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000352 negative regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_2000351 regulation of endothelial cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000353 positive regulation of endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000374 regulation of oxygen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of oxygen metabolic process. http://purl.obolibrary.org/obo/GO_2000385 positive regulation of ectoderm development http://purl.obolibrary.org/obo/GO_2000383 regulation of ectoderm development Any process that activates or increases the frequency, rate or extent of ectoderm development. http://purl.obolibrary.org/obo/GO_2000403 positive regulation of lymphocyte migration http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of lymphocyte migration. http://purl.obolibrary.org/obo/GO_2000405 negative regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_1903975 regulation of glial cell migration Any process that modulates the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_2000459 negative regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_2000464 positive regulation of astrocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000458 regulation of astrocyte chemotaxis Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis. http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_2000472 negative regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_2000473 positive regulation of hematopoietic stem cell migration http://purl.obolibrary.org/obo/GO_2000471 regulation of hematopoietic stem cell migration Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration. http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000496 negative regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000497 positive regulation of cell proliferation involved in compound eye morphogenesis http://purl.obolibrary.org/obo/GO_2000495 regulation of cell proliferation involved in compound eye morphogenesis Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. http://purl.obolibrary.org/obo/GO_2000508 regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000509 negative regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000510 positive regulation of dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000508 regulation of dendritic cell chemotaxis Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000528 negative regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000529 positive regulation of myeloid dendritic cell chemotaxis http://purl.obolibrary.org/obo/GO_2000527 regulation of myeloid dendritic cell chemotaxis Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis. http://purl.obolibrary.org/obo/GO_2000547 regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_2000548 negative regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_2000549 positive regulation of dendritic cell dendrite assembly http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly. http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000106 regulation of leukocyte apoptotic process Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000669 negative regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000670 positive regulation of dendritic cell apoptotic process http://purl.obolibrary.org/obo/GO_2000668 regulation of dendritic cell apoptotic process Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process. http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_0043523 regulation of neuron apoptotic process Any process that modulates the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000672 negative regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000673 positive regulation of motor neuron apoptotic process http://purl.obolibrary.org/obo/GO_2000671 regulation of motor neuron apoptotic process Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process. http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000691 negative regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000700 positive regulation of cardiac muscle cell myoblast differentiation http://purl.obolibrary.org/obo/GO_2000690 regulation of cardiac muscle cell myoblast differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation. http://purl.obolibrary.org/obo/GO_2000790 regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0010464 regulation of mesenchymal cell proliferation Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_2000791 negative regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_2000792 positive regulation of mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_2000790 regulation of mesenchymal cell proliferation involved in lung development Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. http://purl.obolibrary.org/obo/GO_2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/GO_2000818 negative regulation of myoblast proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation. http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000831 regulation of steroid hormone secretion Any process that modulates the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000835 negative regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000836 positive regulation of androgen secretion http://purl.obolibrary.org/obo/GO_2000834 regulation of androgen secretion Any process that activates or increases the frequency, rate or extent of androgen secretion. http://purl.obolibrary.org/obo/GO_2000977 regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/GO_2000978 negative regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/GO_2000979 positive regulation of forebrain neuron differentiation http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. http://purl.obolibrary.org/obo/GO_2001026 regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_2001027 negative regulation of endothelial cell chemotaxis http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis. http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_1902809 regulation of skeletal muscle fiber differentiation Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001036 negative regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001037 positive regulation of tongue muscle cell differentiation http://purl.obolibrary.org/obo/GO_2001035 regulation of tongue muscle cell differentiation Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2001049 regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/GO_2001050 negative regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_2001049 regulation of tendon cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/GO_2001051 positive regulation of tendon cell differentiation http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of tendon cell differentiation. http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_1902105 regulation of leukocyte differentiation Any process that modulates the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/GO_2001199 negative regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/GO_2001200 positive regulation of dendritic cell differentiation http://purl.obolibrary.org/obo/GO_2001198 regulation of dendritic cell differentiation Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development http://purl.obolibrary.org/obo/GO_1903706 regulation of hemopoiesis Any process that modulates the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/GO_2001205 negative regulation of osteoclast development http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/GO_2001206 positive regulation of osteoclast development http://purl.obolibrary.org/obo/GO_2001204 regulation of osteoclast development Any process that activates or increases the frequency, rate or extent of osteoclast development. http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/GO_2001213 negative regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_2001212 regulation of vasculogenesis Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/GO_2001214 positive regulation of vasculogenesis http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates or increases the frequency, rate or extent of vasculogenesis. http://purl.obolibrary.org/obo/PR_000001002 CD19 molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD19 gene or a 1:1 ortholog thereof. It is composed of an N-terminal extracellular domain containing two Ig-like C2-type (immunoglobulin-like) domains, followed by a single-pass transmembrane segment and a cytoplasmic C-terminal tail. CD19 expression is restricted to members of the B cell lineage. It functions as a co-receptor for B-cell antigen receptor (BCR), regulating signal transduction. http://purl.obolibrary.org/obo/PR_000001003 CD34 molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD34 gene or a 1:1 ortholog thereof. It is a leukocyte membrane protein expressed specifically by lymphohematopoietic progenitor cells. It contains a single-pass transmembrane domain and that show distinct expression on early hematopoietic precursors and vascular-associated tissue. Acts as a scaffold that presents selectin carbohydrate ligands in a clustered, tissue specific manner to allow for higher avidity interactions between leukocytes and endothelial cells during the inflammatory process. In common with related sialomucins (endoglycan and podocalyxin), the extracellular region is dominated by an N-terminal mucin-like domain, which is densely substituted with sialylated O-linked carbohydrates. The mucin-like region is followed by a cysteine-containing and presumably globular domain. This domain may fold into an immunoglobulin-like structure as the positions of 2 of the cysteines are conserved in the C2 set of the immunoglobulin superfamily. The cytoplasmic domain is around 73-76 residues long and highly conserved. http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain http://purl.obolibrary.org/obo/PR_000025796 integrin alpha An integrin alpha that contains an A domain. A hallmark of this class is the presence of a von Willebrand factor type A domain (Pfam:PF00092) (I-domain) of approximately 200 amino acid residues at the N terminus, which confers divalent cation binding properties. Unlike other integrin alpha proteins, they do not undergo proteolytic cleavage. http://purl.obolibrary.org/obo/PR_000001006 receptor-type tyrosine-protein phosphatase C http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human PTPRC gene or a 1:1 ortholog thereof. It is composed of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic protein-tyrosine phosphatase domains. Contains 1 to 3 copies of the Fibronectin type III domain (Pfam:PF00041) followed by two copies of the Protein-tyrosine phosphatase (Pfam:PF00102) domain. Receptor-type tyrosine-protein phosphatase C (CD45) regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T and B cells. Multiple isoforms of CD45 (180-235 kDa) can be generated asa result of alternative splicing of three variable exons 4(A), 5(B) and 6(C), encoding sequences at the N-terminal extracellular domain of the molecule. http://purl.obolibrary.org/obo/PR_000001012 integrin alpha-M http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAM gene or a 1:1 ortholog thereof. They constitute subunits of the integrin alpha-M/beta-2 receptor. This receptor is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is also a receptor for fibrinogen, factor X and ICAM1. http://purl.obolibrary.org/obo/PR_000001013 integrin alpha-X http://purl.obolibrary.org/obo/PR_000001005 integrin alpha with A domain An integrin alpha with A domain that is a translation product of the human ITGAX gene or a 1:1 ortholog thereof. Integrin alpha-X complexed with beta-2 is a receptor for fibrinogen. It recognizes the sequence GPR in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis. http://purl.obolibrary.org/obo/PR_000001015 receptor-type tyrosine-protein phosphatase C isoform CD45RA http://purl.obolibrary.org/obo/PR_000050216 receptor-type tyrosine-protein phosphatase C isoform CD45R A receptor-type tyrosine-protein phosphatase C isoform CD45R that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P08575-8 or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001020 CD3 epsilon http://purl.obolibrary.org/obo/PR_000001018 CD3 subunit with immunoglobulin domain A CD3 subunit with immunoglobulin domain that is a translation product of the human CD3E gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein with a domain composition consisting of a large extracellular domain, including five Ig-like C2-type domains followed by two copies of the Fibronectin type-III domain (Pfam:PF00041), a single-pass transmembrane domain and a short cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM http://purl.obolibrary.org/obo/PR_000001022 neural cell adhesion molecule A neural cell adhesion molecule that is involved in neuronal development, synaptic plasticity, and regeneration. http://purl.obolibrary.org/obo/PR_000001024 neural cell adhesion molecule 1 http://purl.obolibrary.org/obo/PR_000001023 neural cell adhesion molecule NCAM A neural cell adhesion molecule NCAM that is a translation product of the human NCAM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001083 CD2 molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001084 T-cell surface glycoprotein CD8 alpha chain http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD8A gene or a 1:1 ortholog thereof. CD8 is a transmembrane that is a co-receptor for MHC class-I antigen/T-cell receptor interaction. The most common form of CD8 is composed of a CD8 alpha and a CD8 beta chain. http://purl.obolibrary.org/obo/PR_000001087 adhesion G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor A G-protein coupled receptor with a 7 transmembrane (secretin family) domain (Pfam:PF00002) preceded by an amino-terminal region containing one or more functional domains with adhesion-like motifs. http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor A G-protein coupled receptor that contains the 7 transmembrane receptor (rhodopsin family) domain (Pfam:PF00001), which includes 7 transmembrane helices (TMI-TM7) with 3 intracellular loops (IL1-IL3) and 3 extracellular loops (EL1-EL3) between the helices. The amino-terminal region is extracellular and the carboxyl-terminal region is intracellular. Rhodopsin-like G-protein coupled receptors (GPCRs) are unique among the several classes of GPCRs in that most have a very short amino-terminal segment and several characteristic sequence motifs, particularly NSxxNPxxY in TM7 and D/E-R-Y/F between TM3 and loop IL2. Most bind their ligands within a cavity between the TM regions. http://purl.obolibrary.org/obo/PR_000001107 D(1)-like dopamine receptor http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor A dopamine receptor that is a product of the DRD1 or DRD5 gene. The active form binds dopamine and its activity is mediated by G proteins that cause activation of adenylate cyclase. http://purl.obolibrary.org/obo/PR_000001108 D(2)-like dopamine receptor http://purl.obolibrary.org/obo/PR_000044633 dopamine receptor A dopamine receptor that is a product of the DRD2, DRD3, or DRD4 gene. The active form binds dopamine and its activity is mediated by G proteins that cause inhibition of adenylate cyclase. http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that in active form binds to one or more chemokines. http://purl.obolibrary.org/obo/PR_000001175 D(1A) dopamine receptor http://purl.obolibrary.org/obo/PR_000001107 D(1)-like dopamine receptor A D(1)-like dopamine receptor that is a translation product of the human DRD1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001177 D(2) dopamine receptor http://purl.obolibrary.org/obo/PR_000001108 D(2)-like dopamine receptor A D(2)-like dopamine receptor that is a translation product of the human DRD2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001199 C-C chemokine receptor type 2 http://purl.obolibrary.org/obo/PR_000001128 chemokine receptor A chemokine receptor that is a translation product of the human CCR2 gene or a 1:1 ortholog thereof. The preferred ligands include CCL2, CCL7, CCL8, CCL13. http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that contains the ADP-ribosyl cyclase domain (Pfam:PF02267). http://purl.obolibrary.org/obo/PR_000001289 membrane-spanning 4-domains subfamily A member 1 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human MS4A1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001327 cadherin http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that has a core domain structure of signal sequence, propeptide, five Cadherin domains (Pfam:PF00028), a transmembrane region, and a Cadherin cytoplasmic region (Pfam:PF01049). Cadherins function as adhesion molecules that mediate Ca2+-dependent cell-cell adhesion in solid tissues. http://purl.obolibrary.org/obo/PR_000001332 cell adhesion molecule CEACAM8 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CEACAM8 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein with a core domain architecture consisting of an extracellular domain containing two copies of the Immunoglobulin domain (Pfam:PF00047), followed by a single-pass transmembrane region and a small intracellular domain. The active protein is a low affinity receptor for immunoglobulin gamma chain Fc region. Human II-a, II-b, and II-c represent a recent gene expansion and are equally related to mouse II, III, and IV. Human III-A and III-B are closely related and closer to mouse IV than to mouse III. http://purl.obolibrary.org/obo/PR_000001408 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 http://purl.obolibrary.org/obo/PR_000001281 ADP-ribosyl cyclase An ADP-ribosyl cyclase that is a translation product of the human CD38 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001444 cadherin-5 http://purl.obolibrary.org/obo/PR_000001327 cadherin A cadherin that is a translation product of the human CDH5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001483 low affinity immunoglobulin gamma Fc region receptor III http://purl.obolibrary.org/obo/PR_000001355 immunoglobulin gamma Fc receptor II/III/IV An immunoglobulin gamma Fc receptor II/III/IV that is a translation product of the mouse Fcgr3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001551 relaxin family peptide receptor protein http://purl.obolibrary.org/obo/PR_000001094 rhodopsin-like G-protein coupled receptor A rhodopsin-like G-protein coupled receptor that is a translation product of the human RXFP1 to RXFP4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The active form binds relaxins. http://purl.obolibrary.org/obo/PR_000001666 relaxin receptor 1 http://purl.obolibrary.org/obo/PR_000001551 relaxin family peptide receptor protein A relaxin family peptide receptor protein that is a translation product of the human RXFP1 gene or a 1:1 ortholog thereof. This receptor is expressed in the brain, kidney, testis, placenta, uterus, ovary, adrenal, prostate, skin and heart. http://purl.obolibrary.org/obo/PR_000001753 transcription factor NF-kappa-B subunit http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that has a core domain composition consisting of a Rel homology domain (RHD) (Pfam:PF00554), an IPT/TIG domain (Pfam:PF01833), six copies of the Ankyrin repeat (Pfam:PF00023), a Death domain (Pfam:PF00531) and a C-terminal PEST region. http://purl.obolibrary.org/obo/PR_000001785 prominin http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein with core architecture consisting of one Prominin (Pfam:PF05478) domain. The prominins are an emerging family of proteins that, among the multispan membrane proteins, display a novel topology. Mouse and human prominin and prominin-like 1 are predicted to contain five membrane spanning domains, with an N-terminal domain exposed to the extracellular space followed by four, alternating small cytoplasmic and large extracellular, loops and a cytoplasmic C-terminal domain. http://purl.obolibrary.org/obo/PR_000001786 prominin-1 http://purl.obolibrary.org/obo/PR_000001785 prominin A prominin that is a translation product of the human PROM1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001809 CD59-like glycoprotein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD59 gene, a 1:1 ortholog thereof, or pro-orthologs thereof. http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein with core architecture consisting of asignal sequence, 5 Ig-like domains, followed by a transmembrane sequence, followed by a Protein tyrosine kinase domain (Pfam:PF07714). However, only 1-3 of the Ig domains are detected by the Pfam HMMs in most of the sequences. Pfam:PF00047 is most common, but other members of the Ig domain clan, Pfam:PF07679 and Pfam:PF07686 can be identified instead. The fourth Ig domain lacks the disulfide-bonded cysteines. http://purl.obolibrary.org/obo/PR_000001813 adhesion G protein-coupled receptor E1 http://purl.obolibrary.org/obo/PR_000001087 adhesion G-protein coupled receptor An adhesion G-protein coupled receptor that is a translation product of the human ADGRE1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001832 SIRP/SHPS-1 family protein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein with core architecture consisting of a signal sequence, one Immunoglobulin V-set domain (Pfam:PF07686), two Immunoglobulin C1-set domains (Pfam:PF07654), a single-pass transmembrane region and a very small cytoplasmic region. http://purl.obolibrary.org/obo/PR_000001836 CD7 molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD7 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001839 T-cell surface glycoprotein CD5 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001843 Thy-1 membrane glycoprotein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human THY1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001850 cathepsin K http://purl.obolibrary.org/obo/PR_000040662 cathepsin-like protease A cathepsin-like protease that is a translation product of the human CTSK gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001865 interleukin-3 receptor class 2 alpha chain http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human IL3RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001867 interleukin-5 receptor subunit alpha http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human IL5RA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001869 interleukin-7 receptor subunit alpha http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human IL7R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001883 lysosome-associated membrane protein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein with core architecture consisting of a Lysosome-associated membrane glycoprotein (Pfam:PF01299) domain. It is a single-pass type I membrane protein that shuttles between lysosomes, endosomes, and the plasma membrane. http://purl.obolibrary.org/obo/PR_000001889 CD14 molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD14 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001892 CD33 molecule http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human CD33 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001898 neprilysin http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human MME gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001937 tartrate-resistant acid phosphatase type 5 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human ACP5 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001944 transcription factor PU.1 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human SPI1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001945 transferrin receptor protein 1 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human TFRC gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001954 tumor necrosis factor receptor superfamily member 11A http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human TNFRSF11A gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001968 tyrosine-protein phosphatase non-receptor type substrate 1 http://purl.obolibrary.org/obo/PR_000001832 SIRP/SHPS-1 family protein A SIRP/SHPS-1 family protein that is a translation product of the human SIRPA gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001969 urokinase plasminogen activator surface receptor http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human PLAUR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein with core architecture consisting of a signal sequence, followed by 7 Ig-like domains (Pfam:PF00047, Pfam:PF07679, or Pfam:PF07686), a transmembrane region, and a cytoplasmic Protein tyrosine kinase domain. http://purl.obolibrary.org/obo/PR_000002001 receptor-type tyrosine-protein kinase FLT3 http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human FLT3 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002062 macrophage colony-stimulating factor 1 receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human CSF1R gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002064 macrosialin http://purl.obolibrary.org/obo/PR_000001883 lysosome-associated membrane protein A lysosome-associated membrane protein that is a translation product of the human CD68 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002065 mast/stem cell growth factor receptor http://purl.obolibrary.org/obo/PR_000001810 CSF-1/PDGF receptor-type tyrosine-protein kinase A CSF-1/PDGF receptor-type tyrosine-protein kinase that is a translation product of the human KIT gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002112 vascular endothelial growth factor receptor 2 http://purl.obolibrary.org/obo/PR_000001971 vascular endothelial growth factor receptor A vascular endothelial growth factor receptor that is a translation product of the human KDR gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is the translation product of any of the LY6 genes (LY6A-LY6I). http://purl.obolibrary.org/obo/PR_000002978 lymphocyte antigen 6G http://purl.obolibrary.org/obo/PR_000002976 Ly-6-like protein An Ly-6-like protein that is a translation product of the mouse Ly6g gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000002981 lymphocyte antigen 76 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A protein that is a translation product of the Ly76 gene in mouse. http://purl.obolibrary.org/obo/PR_000018263 amino acid chain http://purl.obolibrary.org/obo/CHEBI_50047 organic amino compound A molecule that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. http://purl.obolibrary.org/obo/PR_000025796 integrin alpha http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is composed of a long N-terminal extracellular domain, a transmembrane domain and a short cytoplasmic C-terminal domain. The N-terminal domain contains beta-propeller repeats (interrupted by an A domain in a subset of integrins alpha), while the C-terminal domain contains a GFFxR motif. http://purl.obolibrary.org/obo/PR_000030035 G-protein coupled receptor http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that has G protein-coupled receptor (GPCR) activity. Each GPCR consists of a single polypeptide with an extracellular N-terminus, an intracellular C-terminus and seven hydrophobic transmembrane domains (TM1-TM7) linked by three extracellular loops (ECL1-ECL3) and three intracellular loops (ICL1-ICL3). GPCRs function as part of a heterotrimeric complex to transmit an extracellular signal across the membrane by activating an associated G-protein via the exchange of GDP for GTP on the alpha subunit. http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is encoded in the genome of some Eukaryota. http://purl.obolibrary.org/obo/PR_000040662 cathepsin-like protease http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is a translation product of some metazoan gene that encodes a signal peptide followed by a single Cathepsin propeptide inhibitor domain (Pfam:PF08246) followed by a single Papain family cysteine protease (Pfam:PF00112) domain at the C terminus. http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein http://purl.obolibrary.org/obo/PR_000036194 eukaryotic protein A protein that is encoded in the genome of Mus musculus. http://purl.obolibrary.org/obo/PR_P09581 macrophage colony-stimulating factor 1 receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A macrophage colony-stimulating factor 1 receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22091 T-cell acute lymphocytic leukemia protein 1 homolog (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell acute lymphocytic leukemia protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O09100 endothelial transcription factor GATA-2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An endothelial transcription factor GATA-2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P16872 interleukin-7 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-7 receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P17433 transcription factor PU.1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transcription factor PU.1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P17679 erythroid transcription factor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An erythroid transcription factor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P19437 B-lymphocyte antigen CD20 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A membrane-spanning 4-domains subfamily A member 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P21183 interleukin-5 receptor subunit alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An interleukin-5 receptor subunit alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22646 T-cell surface glycoprotein CD3 epsilon chain (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD3 epsilon that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P22858 parathyroid hormone-related protein (mouse) http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein A parathyroid hormone-related protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55097 cathepsin K (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cathepsin K that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55099 tachykinin-3 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tachykinin-3 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P55284 cadherin-5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A cadherin-5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P56528 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P60041 somatostatin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A somatostatin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P61148 fibroblast growth factor 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P61168 D(2) dopamine receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A D(2) dopamine receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q62351 transferrin receptor protein 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A transferrin receptor protein 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q63994 myeloid cell surface antigen CD33 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD33 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q64314 hematopoietic progenitor cell antigen CD34 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD34 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/RO_0002577 system http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity consisting of multiple components that are causally integrated. http://purl.obolibrary.org/obo/CL_0011115 precursor cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that, by division or terminal differentiation, can give rise to other cell types. http://purl.obolibrary.org/obo/GO_0140029 exocytic process http://purl.obolibrary.org/obo/GO_0009987 cellular process The cellular processes that contribute to exocytosis. http://purl.obolibrary.org/obo/GO_0140039 cell-cell adhesion in response to extracellular stimulus http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion The attachment of one cell to another cell via adhesion molecules as a result of an extracellular stimulus. http://purl.obolibrary.org/obo/GO_0099170 postsynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the postsynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0099171 presynaptic modulation of chemical synaptic transmission http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process, acting in the presynapse that results in modulation of chemical synaptic transmission. http://purl.obolibrary.org/obo/GO_0099172 presynapse organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a presynapse. http://purl.obolibrary.org/obo/GO_0099175 regulation of postsynapse organization http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the physical form of a postsynapse. http://purl.obolibrary.org/obo/CHEBI_140325 secondary carboxamide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR1. http://purl.obolibrary.org/obo/CHEBI_140326 tertiary carboxamide http://purl.obolibrary.org/obo/CHEBI_37622 carboxamide A carboxamide resulting from the formal condensation of a carboxylic acid with a secondary amine; formula RC(=O)NHR1R2. http://purl.obolibrary.org/obo/GO_0120192 tight junction assembly http://purl.obolibrary.org/obo/GO_0007043 cell-cell junction assembly A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity A part of a cellular organism consisting of a material entity with granularity above the level of a protein complex but below that of an anatomical system. Note that cellular organisms exclude viruses. http://purl.obolibrary.org/obo/GO_0062149 detection of stimulus involved in sensory perception of pain http://purl.obolibrary.org/obo/GO_0050906 detection of stimulus involved in sensory perception The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal. http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality http://purl.obolibrary.org/obo/PATO_0001241 physical object quality A quality of continuant that exist at the anatomical level of organisation and anything under it. This includes, but is not limited to, cells , tissues, and components. http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality http://purl.obolibrary.org/obo/PATO_0070044 anatomical structure quality A quality inhering in an anotomical structure by virtue of its capacity to be stained by specific histological dyes. http://purl.obolibrary.org/obo/PATO_0070046 neutrophillic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction that stains and colors, pale-pink, with Wright-Giemsa stain. http://purl.obolibrary.org/obo/PATO_0070047 polychromatophilic http://purl.obolibrary.org/obo/PATO_0070045 anatomical histological quality An affinity inhering in an anatomical structure by virtue of the bearer exhibiting a molecular interaction for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/PATO_0040072 high nuclear/cytoplasmic ratio http://purl.obolibrary.org/obo/PATO_0001396 cellular quality A quality inhering in a cell by virtue of the cell having a high nuclear/cytoplasmic ratio. http://purl.obolibrary.org/obo/CL_4023064 caudal ganglionic eminence derived interneuron http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron An interneuron that is derived from the caudal ganglionic eminence. http://purl.obolibrary.org/obo/PHIPO_0001324 normal growth on pyrimethanil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrimethanil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001325 normal growth on tebuconazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to tebuconazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001326 normal growth on prochloraz http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to prochloraz (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001327 normal growth on iprodione http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to iprodione (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001328 normal growth on myclobutanil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to myclobutanil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001329 normal growth on fluazinam http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to fluazinam (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001330 normal growth on thiram http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to thiram (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001331 normal growth on procymidone http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to procymidone (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001332 resistance to procymidone http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to procymidone. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001333 resistance to thiram http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to thiram. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001334 resistance to fluazinam http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fluazinam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001335 resistance to myclobutanil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to myclobutanil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001336 sensitive to myclobutanil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to myclobutanil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001337 sensitive to fluazinam http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluazinam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001338 sensitive to thiram http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to thiram. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001339 sensitive to procymidone http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to procymidone. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001340 resistance to nocodazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to nocodazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001341 normal growth on thiabendazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to thiabendazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/CL_4307033 Astro-NT NN_1 Mecom astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Mecom (Mmus), Fbln5 (Mmus), Prelp (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Mecom, Prelp. These cells are located in the Medulla, Cerebellum, brain , in or close to the regions: Ventral cochlear nucleus, Paraflocculus, Flocculus, Dorsal cochlear nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5213 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4307041 Astro-TE NN_1 Jph4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Sptbn2 (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Jph4, Alpk1. It is glutamatergic (inferred from expression of Aldh1a1, Slc17a7). These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5221 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307028 Astro-NT NN_1 Galnt15 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Galnt15 (Mmus), Agt (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Galnt15. These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5208 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Lhfpl3 (Mmus), Gria1 (Mmus), Hopx (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1159 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4072102 Purkinje layer interneuron http://purl.obolibrary.org/obo/CL_4023057 cerebellar inhibitory GABAergic interneuron A type of GABAergic interneuron residing in the Purkinje cell layer of the cerebellar cortex. http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1181 COP NN_1. http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcriptomically defined type of astrocyte located exclusively in the olfactory areas. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:320 Astro-OLF NN. http://purl.obolibrary.org/obo/CL_4307069 beta1-tancyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A beta1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Frzb (Mmus), Foxd2os (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Col25a1, C230072F16Rik. These cells are located in the Hypothalamus, brain , in or close to the regions: third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5249 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4301571 DCO Il22 Gly-Gaba_1 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Il22 (Mmus), Rftn1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1141 DCO Il22 Gly-Gaba_1. http://purl.obolibrary.org/obo/CL_4307085 CHOR NN_1 Slc17a8 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Slc17a8 (Mmus). It is distinguished from other CHOR NN cells by expression of Slc17a8. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the brain , in or close to the regions: choroid plexus, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5265 CHOR NN_1. http://purl.obolibrary.org/obo/CL_4307053 Astro-OLF NN_2 Slc25a34 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Hs3st3a1 (Mmus), Slc25a34 (Mmus), C4b (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Slc25a34, C4b. These cells are located in the Olfactory areas, brain , in or close to the regions: Main olfactory bulb, outer plexiform layer, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5233 Astro-OLF NN_2. http://purl.obolibrary.org/obo/CL_4307086 OPC NN_1 Neil3 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Mki67 (Mmus), Foxg1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Foxg1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5266 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307109 OEC NN_1 Adamts12 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn5 (Mmus), Adamts12 (Mmus). It is distinguished from other OEC cells by expression of Adamts12. These cells are located in the brain , in or close to the regions: olfactory nerve layer of main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5289 OEC NN_1. http://purl.obolibrary.org/obo/CL_4300101 STR D1 Gaba direct pathway medium spiny neuron (Mmus) http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron A direct pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prkch (Mmus), Slc32a1 (Mmus), Drd1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:061 STR D1 Gaba. http://purl.obolibrary.org/obo/CL_0020003 internal globus pallidus core projecting neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi) of primates, in the central “core” region. It expresses parvalbumin, is primarily GABAergic, and projects to motor thalamic nuclei including the ventral anterior, ventrolateral, and ventromedial nuclei. In the rodent homolog (entopeduncular nucleus), the core subregion is characterized by concentrated parvalbumin-positive neurons targeting the ventral anterior-ventral lateral thalamic nucleus and receives inputs from the dorsolateral striatum innervated by sensorimotor cortices (Miyamoto & Fukuda, 2022). This neuron corresponds to the sensorimotor output population of the GPi, as demonstrated in human tissue and cross-species comparative studies (Wallace et al., 2017) and by classic tracing in primates (Parent & De Bellefeuille, 1982; Parent et al., 2001). http://purl.obolibrary.org/obo/CL_0020004 internal globus pallidus shell projection neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A projection neuron that has its soma located in the internal segment of the globus pallidus (GPi), in the peripheral 'shell' region. In mice and primates, it expresses somatostatin and shows dual expression of GABAergic and glutamatergic markers, enabling co-release of GABA and glutamate (Wallace et al., 2017). It projects primarily to the lateral habenula (Parent & De Bellefeuille, 1982; Wallace et al., 2017), forming the limbic/aversive output stream of the GPi. http://purl.obolibrary.org/obo/CL_0020006 OB-Dopa-GABA http://purl.obolibrary.org/obo/CL_0002613 striatum neuron A transcriptomically defined GABAergic neuron coexpressing dopamine located in the olfactory bulb and part of the striatum. http://purl.obolibrary.org/obo/CL_0020007 dorso-striatal cholinergic-GABAergic neuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A transcriptomically defined GABAergic neuron in the dorsal striatum. In mice and primates, it is defined by the coexpression of choline acetyltransferase (ChAT) together with the GABAergic markers glutamate decarboxylase 65 (GAD65/Gad2) and vesicular GABA transporter (VGAT/Slc32a1) (Lozovaya et al., 2018). http://purl.obolibrary.org/obo/CL_0020008 striatal cholinergic-GABAergic neuron http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A large aspiny interneuron of the striatum that serves as the principal intrinsic source of acetylcholine while simultaneously releasing GABA. It is defined by coexpression of cholinergic markers (ChAT and VAChT/Slc18a3) and GABAergic markers (GAD65/Gad2 and VGAT/Slc32a1) (Lozovaya et al., 2018). This MGE-derived neuron maintains Lhx6 expression associated with dual-transmitter identity (Fragkouli et al., 2009; Marin et al., 2000). Morphologically, it possesses a large soma (20–50 μm diameter), 2–4 thick aspiny dendrites extending radially ~1 mm, and locally ramified axons with hundreds of thousands of varicosities (Wilson et al., 1990; Lim et al., 2014). http://purl.obolibrary.org/obo/CL_0020009 prototypic neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic neuron located in the external globus pallidus (GPe) that constitutes approximately two-thirds of all GPe neurons (Mallet et al., 2012, Dodson et al., 2015). Derived from the medial ganglionic eminence, this cell selectively expresses Nkx2-1, with roughly two-thirds co-expressing parvalbumin (PV) and one-third lacking it in mice (Mallet et al., 2012; Dodson et al., 2015). http://purl.obolibrary.org/obo/CL_0020010 arkypallidal neuron http://purl.obolibrary.org/obo/CL_0012001 neuron of the forebrain A GABAergic projection neuron located in the external segment of the globus pallidus (GPe) and defined by its exclusive projection to the dorsal striatum rather than to the subthalamic nucleus or basal ganglia output nuclei. In rodents and primates, it is characterized molecularly by expression of FOXP2, MEIS2, and NPAS1, and lacks expression of canonical pallidal markers NKX2-1 and LHX6 (Dodson et al., 2015; Abdi et al., 2015; Courtney et al., 2023). This neuron is GABAergic (GAD1/2⁺, SLC32A1/VGAT⁺) and typically PV⁻, forming the transcriptionally and developmentally LGE-derived subclass of GPe neurons (Dodson et al., 2015; Mallet et al., 2012). http://purl.obolibrary.org/obo/GO_0008219 cell death http://purl.obolibrary.org/obo/GO_0009987 cellular process Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538). http://purl.obolibrary.org/obo/GO_0008233 peptidase activity http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. http://purl.obolibrary.org/obo/GO_0008277 regulation of G protein-coupled receptor signaling pathway http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that stops, prevents or reduces the rate or extent of cell proliferation. http://purl.obolibrary.org/obo/GO_0008292 acetylcholine biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline. http://purl.obolibrary.org/obo/GO_0008299 isoprenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of an isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. http://purl.obolibrary.org/obo/GO_0008320 protein transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity Enables the transfer of a protein from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0008347 glial cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. http://purl.obolibrary.org/obo/GO_0008366 axon ensheathment http://purl.obolibrary.org/obo/GO_0007272 ensheathment of neurons Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. http://purl.obolibrary.org/obo/GO_0008502 melatonin receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. http://purl.obolibrary.org/obo/GO_0008544 epidermis development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. http://purl.obolibrary.org/obo/GO_0008594 photoreceptor cell morphogenesis http://purl.obolibrary.org/obo/GO_0048667 cell morphogenesis involved in neuron differentiation The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. http://purl.obolibrary.org/obo/GO_0009056 catabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process A cellular process consisting of the biochemical pathways by which a living organism breaks down substances. This includes the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. http://purl.obolibrary.org/obo/GO_0009085 L-lysine biosynthetic process http://purl.obolibrary.org/obo/GO_0009067 aspartate family amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of L-lysine, 2,6-diaminohexanoic acid. http://purl.obolibrary.org/obo/GO_0009295 nucleoid http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined. http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009309 amine biosynthetic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009310 amine catabolic process http://purl.obolibrary.org/obo/GO_0009308 amine metabolic process The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. http://purl.obolibrary.org/obo/GO_0009314 response to radiation http://purl.obolibrary.org/obo/GO_0009628 response to abiotic stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. http://purl.obolibrary.org/obo/GO_0009403 toxin biosynthetic process http://purl.obolibrary.org/obo/GO_0009404 toxin metabolic process The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. http://purl.obolibrary.org/obo/GO_0009404 toxin metabolic process http://purl.obolibrary.org/obo/GO_0019748 secondary metabolic process The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. http://purl.obolibrary.org/obo/GO_0009448 gamma-aminobutyric acid metabolic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0009449 gamma-aminobutyric acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170043 non-proteinogenic amino acid biosynthetic process The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0009450 gamma-aminobutyric acid catabolic process http://purl.obolibrary.org/obo/GO_0170044 non-proteinogenic amino acid catabolic process The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. http://purl.obolibrary.org/obo/GO_0009507 chloroplast http://purl.obolibrary.org/obo/GO_0009536 plastid A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. http://purl.obolibrary.org/obo/GO_0009508 plastid chromosome http://purl.obolibrary.org/obo/GO_0005694 chromosome A circular DNA molecule containing plastid encoded genes. http://purl.obolibrary.org/obo/GO_0009526 plastid envelope http://purl.obolibrary.org/obo/GO_0031967 organelle envelope The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0009527 plastid outer membrane http://purl.obolibrary.org/obo/GO_0042170 plastid membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope. http://purl.obolibrary.org/obo/GO_0009532 plastid stroma http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The proteinaceous ground substance of plastids. http://purl.obolibrary.org/obo/GO_0009570 chloroplast stroma http://purl.obolibrary.org/obo/GO_0009532 plastid stroma The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis. http://purl.obolibrary.org/obo/GO_0009581 detection of external stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an external stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009582 detection of abiotic stimulus http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0009626 plant-type hypersensitive response http://purl.obolibrary.org/obo/GO_0034050 symbiont-induced defense-related programmed cell death The rapid, localized death of plant cells in response to invasion by a pathogen. http://purl.obolibrary.org/obo/GO_0009657 plastid organization http://purl.obolibrary.org/obo/GO_0006996 organelle organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid. http://purl.obolibrary.org/obo/GO_0009658 chloroplast organization http://purl.obolibrary.org/obo/GO_0009657 plastid organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast. http://purl.obolibrary.org/obo/GO_0009665 plastid inheritance http://purl.obolibrary.org/obo/GO_0009657 plastid organization The partitioning of plastids between daughter cells at cell division. http://purl.obolibrary.org/obo/GO_0009666 plastid outer membrane organization http://purl.obolibrary.org/obo/GO_0009668 plastid membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid. http://purl.obolibrary.org/obo/GO_0009668 plastid membrane organization http://purl.obolibrary.org/obo/GO_0061024 membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid. http://purl.obolibrary.org/obo/GO_0009707 chloroplast outer membrane http://purl.obolibrary.org/obo/GO_0031969 chloroplast membrane The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope. http://purl.obolibrary.org/obo/GO_0009713 catechol-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0046189 phenol-containing compound biosynthetic process The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. http://purl.obolibrary.org/obo/GO_0009725 response to hormone http://purl.obolibrary.org/obo/GO_0009719 response to endogenous stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate http://purl.obolibrary.org/obo/GO_1901700 response to oxygen-containing compound Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/GO_0009786 regulation of asymmetric cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of asymmetric cell division. http://purl.obolibrary.org/obo/GO_0009790 embryo development http://purl.obolibrary.org/obo/GO_0007275 multicellular organism development The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. http://purl.obolibrary.org/obo/GO_0009847 spore germination http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall). http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009895 negative regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009896 positive regulation of catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. http://purl.obolibrary.org/obo/GO_0009902 chloroplast relocation http://purl.obolibrary.org/obo/GO_0051667 establishment of plastid localization The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery. http://purl.obolibrary.org/obo/GO_0009941 chloroplast envelope http://purl.obolibrary.org/obo/GO_0009526 plastid envelope The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. http://purl.obolibrary.org/obo/GO_0009994 oocyte differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. http://purl.obolibrary.org/obo/GO_0010020 chloroplast fission http://purl.obolibrary.org/obo/GO_0043572 plastid fission The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis. http://purl.obolibrary.org/obo/GO_0010032 meiotic chromosome condensation http://purl.obolibrary.org/obo/GO_0030261 chromosome condensation Compaction of chromatin structure prior to meiosis in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0010070 zygote asymmetric cell division http://purl.obolibrary.org/obo/GO_0008356 asymmetric cell division The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. http://purl.obolibrary.org/obo/GO_0010171 body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the soma are generated and organized. http://purl.obolibrary.org/obo/GO_0010363 regulation of plant-type hypersensitive response http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response. http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010454 negative regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0010453 regulation of cell fate commitment Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010455 positive regulation of cell fate commitment http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation http://purl.obolibrary.org/obo/GO_0045995 regulation of embryonic development Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. http://purl.obolibrary.org/obo/GO_0010481 epidermal cell division http://purl.obolibrary.org/obo/GO_0051301 cell division Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. http://purl.obolibrary.org/obo/GO_0010482 regulation of epidermal cell division http://purl.obolibrary.org/obo/GO_0051302 regulation of cell division Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. http://purl.obolibrary.org/obo/GO_0010496 intercellular transport http://purl.obolibrary.org/obo/GO_0009987 cellular process The movement of substances between cells. http://purl.obolibrary.org/obo/GO_0010506 regulation of autophagy http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm. http://purl.obolibrary.org/obo/GO_0010549 regulation of membrane disassembly http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane disassembly. http://purl.obolibrary.org/obo/GO_0010559 regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010560 positive regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010561 negative regulation of glycoprotein biosynthetic process http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. http://purl.obolibrary.org/obo/GO_0010562 positive regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0010570 regulation of filamentous growth http://purl.obolibrary.org/obo/GO_0040008 regulation of growth Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape. http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0010595 positive regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0010596 negative regulation of endothelial cell migration http://purl.obolibrary.org/obo/GO_0010594 regulation of endothelial cell migration Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0010611 regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010612 regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010613 positive regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010614 negative regulation of cardiac muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. http://purl.obolibrary.org/obo/GO_0010615 positive regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010616 negative regulation of cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0010623 programmed cell death involved in cell development http://purl.obolibrary.org/obo/GO_0048869 cellular developmental process The activation of endogenous cellular processes that result in the death of a cell as part of its development. http://purl.obolibrary.org/obo/GO_0010624 regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0010625 positive regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060252 positive regulation of glial cell proliferation Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0010626 negative regulation of Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0060253 negative regulation of glial cell proliferation Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression http://purl.obolibrary.org/obo/GO_0010557 positive regulation of macromolecule biosynthetic process Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/GO_0010633 negative regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/GO_0010634 positive regulation of epithelial cell migration http://purl.obolibrary.org/obo/GO_0010632 regulation of epithelial cell migration Any process that activates or increases the frequency, rate or extent of epithelial cell migration. http://purl.obolibrary.org/obo/GO_0010635 regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0010636 positive regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0010637 negative regulation of mitochondrial fusion http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment. http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication http://purl.obolibrary.org/obo/GO_0010646 regulation of cell communication Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. http://purl.obolibrary.org/obo/GO_0010656 negative regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle. http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010657 muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations. http://purl.obolibrary.org/obo/GO_0010659 cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010658 striated muscle cell apoptotic process A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010661 positive regulation of muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010660 regulation of muscle cell apoptotic process Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010663 positive regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010664 negative regulation of striated muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010662 regulation of striated muscle cell apoptotic process Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010666 positive regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010667 negative regulation of cardiac muscle cell apoptotic process http://purl.obolibrary.org/obo/GO_0010665 regulation of cardiac muscle cell apoptotic process Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death. http://purl.obolibrary.org/obo/GO_0010700 negative regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0010701 positive regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0010710 regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010711 negative regulation of collagen catabolic process http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010713 negative regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010714 positive regulation of collagen metabolic process http://purl.obolibrary.org/obo/GO_0010712 regulation of collagen metabolic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010716 negative regulation of extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0010715 regulation of extracellular matrix disassembly Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010718 positive regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010719 negative regulation of epithelial to mesenchymal transition http://purl.obolibrary.org/obo/GO_0010717 regulation of epithelial to mesenchymal transition Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0010758 regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010759 positive regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010760 negative regulation of macrophage chemotaxis http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010761 fibroblast migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0010763 positive regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0010764 negative regulation of fibroblast migration http://purl.obolibrary.org/obo/GO_0010762 regulation of fibroblast migration Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. http://purl.obolibrary.org/obo/GO_0010770 positive regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/GO_0010771 negative regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. http://purl.obolibrary.org/obo/GO_0010818 T cell chemotaxis http://purl.obolibrary.org/obo/GO_0072678 T cell migration The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex. http://purl.obolibrary.org/obo/GO_0010819 regulation of T cell chemotaxis http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010820 positive regulation of T cell chemotaxis http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0010821 regulation of mitochondrion organization http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion. http://purl.obolibrary.org/obo/GO_0010830 regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010831 positive regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010832 negative regulation of myotube differentiation http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0010842 retina layer formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. http://purl.obolibrary.org/obo/GO_0010892 positive regulation of mitochondrial translation in response to stress http://purl.obolibrary.org/obo/GO_0070131 positive regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0010893 positive regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0010894 negative regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0010934 macrophage cytokine production http://purl.obolibrary.org/obo/GO_0061082 myeloid leukocyte cytokine production The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0002718 regulation of cytokine production involved in immune response Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0010936 negative regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0010937 regulation of cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031114 regulation of microtubule depolymerization Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization. http://purl.obolibrary.org/obo/GO_0010938 cytoplasmic microtubule depolymerization http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. http://purl.obolibrary.org/obo/GO_0010948 negative regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045786 negative regulation of cell cycle Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0010958 regulation of amino acid import across plasma membrane http://purl.obolibrary.org/obo/GO_1903789 regulation of amino acid transmembrane transport Any process that modulates the frequency, rate or extent of amino acid import into a cell. http://purl.obolibrary.org/obo/GO_0010968 regulation of microtubule nucleation http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010976 positive regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0010977 negative regulation of neuron projection development http://purl.obolibrary.org/obo/GO_0010975 regulation of neuron projection development Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). http://purl.obolibrary.org/obo/GO_0012506 vesicle membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane The lipid bilayer surrounding any membrane-bounded vesicle in the cell. http://purl.obolibrary.org/obo/GO_0014002 astrocyte development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0014003 oligodendrocyte development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. http://purl.obolibrary.org/obo/GO_0014004 microglia differentiation http://purl.obolibrary.org/obo/GO_0030225 macrophage differentiation The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system. http://purl.obolibrary.org/obo/GO_0014005 microglia development http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014006 regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/GO_0014007 negative regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/GO_0014008 positive regulation of microglia differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell. http://purl.obolibrary.org/obo/GO_0014009 glial cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. http://purl.obolibrary.org/obo/GO_0014010 Schwann cell proliferation http://purl.obolibrary.org/obo/GO_0014009 glial cell proliferation The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014014 negative regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014015 positive regulation of gliogenesis http://purl.obolibrary.org/obo/GO_0014013 regulation of gliogenesis Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. http://purl.obolibrary.org/obo/GO_0014016 neuroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. http://purl.obolibrary.org/obo/GO_0014019 neuroblast development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. http://purl.obolibrary.org/obo/GO_0014023 neural rod formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014025 neural keel formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. http://purl.obolibrary.org/obo/GO_0014028 notochord formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. http://purl.obolibrary.org/obo/GO_0014029 neural crest formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. http://purl.obolibrary.org/obo/GO_0014031 mesenchymal cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. http://purl.obolibrary.org/obo/GO_0014037 Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. http://purl.obolibrary.org/obo/GO_0014038 regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that modulates the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/GO_0014039 negative regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/GO_0014040 positive regulation of Schwann cell differentiation http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. http://purl.obolibrary.org/obo/GO_0014041 regulation of neuron maturation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. http://purl.obolibrary.org/obo/GO_0014042 positive regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation Any process that activates or increases the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014043 negative regulation of neuron maturation http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. http://purl.obolibrary.org/obo/GO_0014044 Schwann cell development http://purl.obolibrary.org/obo/GO_0021782 glial cell development The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. http://purl.obolibrary.org/obo/GO_0014047 glutamate secretion http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/GO_0014049 positive regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/GO_0014050 negative regulation of glutamate secretion http://purl.obolibrary.org/obo/GO_0014048 regulation of glutamate secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. http://purl.obolibrary.org/obo/GO_0014051 gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0032890 regulation of organic acid transport Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/GO_0014053 negative regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/GO_0014054 positive regulation of gamma-aminobutyric acid secretion http://purl.obolibrary.org/obo/GO_0014052 regulation of gamma-aminobutyric acid secretion Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. http://purl.obolibrary.org/obo/GO_0014055 acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS). http://purl.obolibrary.org/obo/GO_0014056 regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014057 positive regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014058 negative regulation of acetylcholine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine. http://purl.obolibrary.org/obo/GO_0014059 regulation of dopamine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of dopamine. http://purl.obolibrary.org/obo/GO_0014061 regulation of norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. http://purl.obolibrary.org/obo/GO_0014062 regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport Any process that modulates the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014063 negative regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014064 positive regulation of serotonin secretion http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. http://purl.obolibrary.org/obo/GO_0014733 regulation of skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014734 skeletal muscle hypertrophy http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. http://purl.obolibrary.org/obo/GO_0014741 negative regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014742 positive regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014743 regulation of muscle hypertrophy http://purl.obolibrary.org/obo/GO_0090257 regulation of muscle system process Any process that modulates the frequency, rate or extent of muscle hypertrophy. http://purl.obolibrary.org/obo/GO_0014744 positive regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that activates or increases the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014745 negative regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014807 regulation of somitogenesis http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the frequency, rate or extent of somitogenesis. http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0006942 regulation of striated muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction. http://purl.obolibrary.org/obo/GO_0014852 regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system. http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0014856 skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014858 positive regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014859 negative regulation of skeletal muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014857 regulation of skeletal muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0014860 neurotransmitter secretion involved in regulation of skeletal muscle contraction http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin. http://purl.obolibrary.org/obo/GO_0014861 regulation of skeletal muscle contraction via regulation of action potential http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes. http://purl.obolibrary.org/obo/GO_0014866 skeletal myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. http://purl.obolibrary.org/obo/GO_0014872 myoblast division http://purl.obolibrary.org/obo/GO_0051301 cell division The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0014874 response to stimulus involved in regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0050896 response to stimulus Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation. http://purl.obolibrary.org/obo/GO_0014887 cardiac muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation http://purl.obolibrary.org/obo/GO_0043500 muscle adaptation Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. http://purl.obolibrary.org/obo/GO_0014895 smooth muscle hypertrophy http://purl.obolibrary.org/obo/GO_0014805 smooth muscle adaptation The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. http://purl.obolibrary.org/obo/GO_0014904 myotube cell development http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0030334 regulation of cell migration Any process that modulates the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_0014911 positive regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_0014912 negative regulation of smooth muscle cell migration http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. http://purl.obolibrary.org/obo/GO_0015144 carbohydrate transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of carbohydrate from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0015159 polysaccharide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity Enables the transfer of polysaccharides from one side of a membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0015187 glycine transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0015175 neutral L-amino acid transmembrane transporter activity Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0015669 gas transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015695 organic cation transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0015774 polysaccharide transport http://purl.obolibrary.org/obo/GO_0008643 carbohydrate transport The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. http://purl.obolibrary.org/obo/GO_0015800 acidic amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015812 gamma-aminobutyric acid transport http://purl.obolibrary.org/obo/GO_0006865 amino acid transport The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015816 glycine transport http://purl.obolibrary.org/obo/GO_0015695 organic cation transport The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015849 organic acid transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0015872 dopamine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. http://purl.obolibrary.org/obo/GO_0015874 norepinephrine transport http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. http://purl.obolibrary.org/obo/GO_0016031 tRNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0035927 RNA import into mitochondrion The process in which a tRNA is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0016053 organic acid biosynthetic process http://purl.obolibrary.org/obo/GO_0044283 small molecule biosynthetic process The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process http://purl.obolibrary.org/obo/GO_0044282 small molecule catabolic process The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. http://purl.obolibrary.org/obo/GO_0016057 regulation of membrane potential in photoreceptor cell http://purl.obolibrary.org/obo/GO_0042391 regulation of membrane potential Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon. http://purl.obolibrary.org/obo/GO_0016114 terpenoid biosynthetic process http://purl.obolibrary.org/obo/GO_0008299 isoprenoid biosynthetic process The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure. http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development Any process that modulates the frequency, rate or extent of striated muscle development. http://purl.obolibrary.org/obo/GO_0016241 regulation of macroautophagy http://purl.obolibrary.org/obo/GO_0010506 regulation of autophagy Any process that modulates the frequency, rate or extent of macroautophagy. http://purl.obolibrary.org/obo/GO_0016321 female meiosis chromosome segregation http://purl.obolibrary.org/obo/GO_0045132 meiotic chromosome segregation The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female. http://purl.obolibrary.org/obo/GO_0016525 negative regulation of angiogenesis http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0016528 sarcoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. http://purl.obolibrary.org/obo/GO_0016594 glycine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to glycine, aminoethanoic acid. http://purl.obolibrary.org/obo/GO_0016597 amino acid binding http://purl.obolibrary.org/obo/GO_0005488 binding Binding to an amino acid, organic acids containing one or more amino substituents. http://purl.obolibrary.org/obo/GO_0016746 acyltransferase activity http://purl.obolibrary.org/obo/GO_0016740 transferase activity Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor). http://purl.obolibrary.org/obo/GO_0016817 hydrolase activity, acting on acid anhydrides http://purl.obolibrary.org/obo/GO_0016787 hydrolase activity Catalysis of the hydrolysis of any acid anhydride. http://purl.obolibrary.org/obo/GO_0016877 ligase activity, forming carbon-sulfur bonds http://purl.obolibrary.org/obo/GO_0016874 ligase activity Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. http://purl.obolibrary.org/obo/GO_0017046 peptide hormone binding http://purl.obolibrary.org/obo/GO_0042562 hormone binding Binding to a peptide with hormonal activity in animals. http://purl.obolibrary.org/obo/GO_0017126 nucleologenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. http://purl.obolibrary.org/obo/GO_0017145 stem cell division http://purl.obolibrary.org/obo/GO_0051301 cell division The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. http://purl.obolibrary.org/obo/GO_0019750 chloroplast localization http://purl.obolibrary.org/obo/GO_0051644 plastid localization Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants. http://purl.obolibrary.org/obo/GO_0019755 one-carbon compound transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0019867 outer membrane http://purl.obolibrary.org/obo/GO_0016020 membrane The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. http://purl.obolibrary.org/obo/GO_0021782 glial cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. http://purl.obolibrary.org/obo/GO_0022406 membrane docking http://purl.obolibrary.org/obo/GO_0009987 cellular process The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. http://purl.obolibrary.org/obo/GO_0022604 regulation of cell morphogenesis http://purl.obolibrary.org/obo/GO_0022603 regulation of anatomical structure morphogenesis Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. http://purl.obolibrary.org/obo/GO_0022617 extracellular matrix disassembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process that results in the breakdown of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0022804 active transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction. http://purl.obolibrary.org/obo/GO_0022884 macromolecule transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a macromolecule from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. http://purl.obolibrary.org/obo/GO_0030225 macrophage differentiation http://purl.obolibrary.org/obo/GO_1903131 mononuclear cell differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly Formation of myofibrils, the repeating units of striated muscle. http://purl.obolibrary.org/obo/GO_0030397 membrane disassembly http://purl.obolibrary.org/obo/GO_0061024 membrane organization The controlled breakdown of any cell membrane in the context of a normal process such as autophagy. http://purl.obolibrary.org/obo/GO_0030574 collagen catabolic process http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. http://purl.obolibrary.org/obo/GO_0030658 transport vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a transport vesicle. http://purl.obolibrary.org/obo/GO_0030660 Golgi-associated vesicle membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. http://purl.obolibrary.org/obo/GO_0030705 cytoskeleton-dependent intracellular transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. http://purl.obolibrary.org/obo/GO_0030951 establishment or maintenance of microtubule cytoskeleton polarity http://purl.obolibrary.org/obo/GO_0030952 establishment or maintenance of cytoskeleton polarity Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0031032 actomyosin structure organization http://purl.obolibrary.org/obo/GO_0030036 actin cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. http://purl.obolibrary.org/obo/GO_0031090 organelle membrane http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. http://purl.obolibrary.org/obo/GO_0031113 regulation of microtubule polymerization http://purl.obolibrary.org/obo/GO_0031110 regulation of microtubule polymerization or depolymerization Any process that modulates the frequency, rate or extent of microtubule polymerization. http://purl.obolibrary.org/obo/GO_0031122 cytoplasmic microtubule organization http://purl.obolibrary.org/obo/GO_0000226 microtubule cytoskeleton organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031346 positive regulation of cell projection organization http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. http://purl.obolibrary.org/obo/GO_0031347 regulation of defense response http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress Any process that modulates the frequency, rate or extent of a defense response. http://purl.obolibrary.org/obo/GO_0031514 motile cilium http://purl.obolibrary.org/obo/GO_0005929 cilium A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. http://purl.obolibrary.org/obo/GO_0031969 chloroplast membrane http://purl.obolibrary.org/obo/GO_0042170 plastid membrane Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope. http://purl.obolibrary.org/obo/GO_0031982 vesicle http://purl.obolibrary.org/obo/GO_0043227 membrane-bounded organelle Any small, fluid-filled, spherical organelle enclosed by membrane. http://purl.obolibrary.org/obo/GO_0032056 positive regulation of translation in response to stress http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0032102 negative regulation of response to external stimulus http://purl.obolibrary.org/obo/GO_0048585 negative regulation of response to stimulus Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032223 negative regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032224 positive regulation of synaptic transmission, cholinergic http://purl.obolibrary.org/obo/GO_0032222 regulation of synaptic transmission, cholinergic Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine. http://purl.obolibrary.org/obo/GO_0032413 negative regulation of ion transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0034766 negative regulation of monoatomic ion transmembrane transport Any process that stops or reduces the activity of an ion transporter. http://purl.obolibrary.org/obo/GO_0032870 cellular response to hormone stimulus http://purl.obolibrary.org/obo/GO_0009725 response to hormone Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. http://purl.obolibrary.org/obo/GO_0032879 regulation of localization http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0032885 regulation of polysaccharide biosynthetic process http://purl.obolibrary.org/obo/GO_0032881 regulation of polysaccharide metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. http://purl.obolibrary.org/obo/GO_0032963 collagen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). http://purl.obolibrary.org/obo/GO_0033002 muscle cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The expansion of a muscle cell population by cell division. http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033045 regulation of sister chromatid segregation Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/GO_0033604 negative regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/GO_0033605 positive regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. http://purl.obolibrary.org/obo/GO_0033993 response to lipid http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. http://purl.obolibrary.org/obo/GO_0034050 symbiont-induced defense-related programmed cell death http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont Cell death resulting from activation of endogenous cellular processes after interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). This can be triggered by direct interaction with the organism, for example, contact with penetrating hyphae of a fungus; or an indirect interaction such as symbiont-secreted molecules. http://purl.obolibrary.org/obo/GO_0034219 carbohydrate transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a carbohydrate is transported across a membrane. http://purl.obolibrary.org/obo/GO_0034220 monoatomic ion transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport A process in which a monoatomic ion is transported across a membrane. Monatomic ions (also called simple ions) are ions consisting of exactly one atom. http://purl.obolibrary.org/obo/GO_0034654 nucleobase-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0035914 skeletal muscle cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. http://purl.obolibrary.org/obo/GO_0035927 RNA import into mitochondrion http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a rRNA, ribosomal ribonucleic acid, is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0038187 pattern recognition receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response. http://purl.obolibrary.org/obo/GO_0042063 gliogenesis http://purl.obolibrary.org/obo/GO_0022008 neurogenesis The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. http://purl.obolibrary.org/obo/GO_0042166 acetylcholine binding http://purl.obolibrary.org/obo/GO_0043169 cation binding Binding to acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions. http://purl.obolibrary.org/obo/GO_0042170 plastid membrane http://purl.obolibrary.org/obo/GO_0031090 organelle membrane Either of the lipid bilayers that surround a plastid and form the plastid envelope. http://purl.obolibrary.org/obo/GO_0042435 indole-containing compound biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. http://purl.obolibrary.org/obo/GO_0042445 hormone metabolic process http://purl.obolibrary.org/obo/GO_0010817 regulation of hormone levels The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. http://purl.obolibrary.org/obo/GO_0042551 neuron maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0042646 plastid nucleoid http://purl.obolibrary.org/obo/GO_0009295 nucleoid The region of a plastid to which the DNA is confined. http://purl.obolibrary.org/obo/GO_0042923 neuropeptide binding http://purl.obolibrary.org/obo/GO_0042277 peptide binding Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). http://purl.obolibrary.org/obo/GO_0043065 positive regulation of apoptotic process http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0043067 regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043068 positive regulation of programmed cell death http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes. http://purl.obolibrary.org/obo/GO_0043169 cation binding http://purl.obolibrary.org/obo/GO_0043167 ion binding Binding to a cation, a charged atom or group of atoms with a net positive charge. http://purl.obolibrary.org/obo/GO_0043200 response to amino acid http://purl.obolibrary.org/obo/GO_0001101 response to acid chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. http://purl.obolibrary.org/obo/GO_0043228 membraneless organelle http://purl.obolibrary.org/obo/GO_0043226 organelle Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. http://purl.obolibrary.org/obo/GO_0043269 regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043270 positive regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043271 negative regulation of monoatomic ion transport http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0043462 regulation of ATP-dependent activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the rate of an ATP-dependent activity. http://purl.obolibrary.org/obo/GO_0043501 skeletal muscle adaptation http://purl.obolibrary.org/obo/GO_0014888 striated muscle adaptation Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. http://purl.obolibrary.org/obo/GO_0043502 regulation of muscle adaptation http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of muscle adaptation. http://purl.obolibrary.org/obo/GO_0043542 endothelial cell migration http://purl.obolibrary.org/obo/GO_0016477 cell migration The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. http://purl.obolibrary.org/obo/GO_0043558 regulation of translational initiation in response to stress http://purl.obolibrary.org/obo/GO_0043555 regulation of translation in response to stress Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/GO_0043572 plastid fission http://purl.obolibrary.org/obo/GO_0048285 organelle fission The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. http://purl.obolibrary.org/obo/GO_0044089 positive regulation of cellular component biogenesis http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. http://purl.obolibrary.org/obo/GO_0044091 membrane biogenesis http://purl.obolibrary.org/obo/GO_0044085 cellular component biogenesis A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. http://purl.obolibrary.org/obo/GO_0044111 formation of structure involved in a symbiotic process http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0044403 biological process involved in symbiotic interaction http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms An interaction between two organisms living together in more or less intimate association. Microscopic symbionts are often referred to as endosymbionts. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs. http://purl.obolibrary.org/obo/GO_0044419 biological process involved in interspecies interaction between organisms http://purl.obolibrary.org/obo/GO_0008150 biological process Any process evolved to enable an interaction with an organism of a different species. http://purl.obolibrary.org/obo/GO_0044743 protein transmembrane import into intracellular organelle http://purl.obolibrary.org/obo/GO_0072594 establishment of protein localization to organelle The directed movement of proteins into an intracellular organelle, across a membrane. http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics http://purl.obolibrary.org/obo/GO_0003006 developmental process involved in reproduction The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0045177 apical part of cell http://purl.obolibrary.org/obo/GO_0110165 cellular anatomical structure The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue. http://purl.obolibrary.org/obo/GO_0045184 establishment of protein localization http://purl.obolibrary.org/obo/GO_0051234 establishment of localization The directed movement of a protein to a specific location. http://purl.obolibrary.org/obo/GO_0045229 external encapsulating structure organization http://purl.obolibrary.org/obo/GO_0016043 cellular component organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. http://purl.obolibrary.org/obo/GO_0045445 myoblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers. http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. http://purl.obolibrary.org/obo/GO_0045597 positive regulation of cell differentiation http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell differentiation. http://purl.obolibrary.org/obo/GO_0045646 regulation of erythrocyte differentiation http://purl.obolibrary.org/obo/GO_0045637 regulation of myeloid cell differentiation Any process that modulates the frequency, rate or extent of erythrocyte differentiation. http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0002761 regulation of myeloid leukocyte differentiation Any process that modulates the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/GO_0045650 negative regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/GO_0045651 positive regulation of macrophage differentiation http://purl.obolibrary.org/obo/GO_0045649 regulation of macrophage differentiation Any process that activates or increases the frequency, rate or extent of macrophage differentiation. http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045665 negative regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045666 positive regulation of neuron differentiation http://purl.obolibrary.org/obo/GO_0045664 regulation of neuron differentiation Any process that activates or increases the frequency, rate or extent of neuron differentiation. http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045686 negative regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045687 positive regulation of glial cell differentiation http://purl.obolibrary.org/obo/GO_0045685 regulation of glial cell differentiation Any process that activates or increases the frequency, rate or extent of glia cell differentiation. http://purl.obolibrary.org/obo/GO_0045727 positive regulation of translation http://purl.obolibrary.org/obo/GO_0010628 positive regulation of gene expression Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA or circRNA. http://purl.obolibrary.org/obo/GO_0045765 regulation of angiogenesis http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that modulates the frequency, rate or extent of angiogenesis. http://purl.obolibrary.org/obo/GO_0045785 positive regulation of cell adhesion http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of cell adhesion. http://purl.obolibrary.org/obo/GO_0045912 negative regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045913 positive regulation of carbohydrate metabolic process http://purl.obolibrary.org/obo/GO_0009893 positive regulation of metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. http://purl.obolibrary.org/obo/GO_0045934 negative regulation of nucleobase-containing compound metabolic process http://purl.obolibrary.org/obo/GO_0009892 negative regulation of metabolic process Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids. http://purl.obolibrary.org/obo/GO_0045936 negative regulation of phosphate metabolic process http://purl.obolibrary.org/obo/GO_0010563 negative regulation of phosphorus metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. http://purl.obolibrary.org/obo/GO_0045939 negative regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045833 negative regulation of lipid metabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0045940 positive regulation of steroid metabolic process http://purl.obolibrary.org/obo/GO_0045834 positive regulation of lipid metabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. http://purl.obolibrary.org/obo/GO_0045988 negative regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045932 negative regulation of muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0045989 positive regulation of striated muscle contraction http://purl.obolibrary.org/obo/GO_0045933 positive regulation of muscle contraction Any process that activates or increases the frequency, rate or extent of striated muscle contraction. http://purl.obolibrary.org/obo/GO_0046112 nucleobase biosynthetic process http://purl.obolibrary.org/obo/GO_0009058 biosynthetic process The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid. http://purl.obolibrary.org/obo/GO_0046395 carboxylic acid catabolic process http://purl.obolibrary.org/obo/GO_0016054 organic acid catabolic process The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. http://purl.obolibrary.org/obo/GO_0046467 membrane lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0008610 lipid biosynthetic process The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane. http://purl.obolibrary.org/obo/GO_0046545 development of primary female sexual characteristics http://purl.obolibrary.org/obo/GO_0045137 development of primary sexual characteristics The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. http://purl.obolibrary.org/obo/GO_0046825 regulation of protein export from nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0046831 regulation of RNA export from nucleus http://purl.obolibrary.org/obo/GO_0046822 regulation of nucleocytoplasmic transport Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm. http://purl.obolibrary.org/obo/GO_0046886 positive regulation of hormone biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. http://purl.obolibrary.org/obo/GO_0046889 positive regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009891 positive regulation of biosynthetic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0046929 negative regulation of neurotransmitter secretion http://purl.obolibrary.org/obo/GO_1903531 negative regulation of secretion by cell Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter. http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0048246 macrophage chemotaxis http://purl.obolibrary.org/obo/GO_0030595 leukocyte chemotaxis The movement of a macrophage in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0048520 positive regulation of behavior http://purl.obolibrary.org/obo/GO_0050795 regulation of behavior Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. http://purl.obolibrary.org/obo/GO_0048570 notochord morphogenesis http://purl.obolibrary.org/obo/GO_0048562 embryonic organ morphogenesis The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. http://purl.obolibrary.org/obo/GO_0048581 negative regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051241 negative regulation of multicellular organismal process Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048582 positive regulation of post-embryonic development http://purl.obolibrary.org/obo/GO_0051240 positive regulation of multicellular organismal process Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. http://purl.obolibrary.org/obo/GO_0048628 myoblast maturation http://purl.obolibrary.org/obo/GO_0048469 cell maturation A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/GO_0048635 negative regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. http://purl.obolibrary.org/obo/GO_0048636 positive regulation of muscle organ development http://purl.obolibrary.org/obo/GO_0048634 regulation of muscle organ development Any process that activates, maintains or increases the rate of muscle development. http://purl.obolibrary.org/obo/GO_0048638 regulation of developmental growth http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of developmental growth. http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048642 negative regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048643 positive regulation of skeletal muscle tissue development http://purl.obolibrary.org/obo/GO_0048641 regulation of skeletal muscle tissue development Any process that activates, maintains or increases the rate of skeletal muscle tissue development. http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. http://purl.obolibrary.org/obo/GO_0048709 oligodendrocyte differentiation http://purl.obolibrary.org/obo/GO_0010001 glial cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0048864 stem cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. http://purl.obolibrary.org/obo/GO_0050432 catecholamine secretion http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0050433 regulation of catecholamine secretion http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. http://purl.obolibrary.org/obo/GO_0050767 regulation of neurogenesis http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function Any process that modulates the activity of an enzyme. http://purl.obolibrary.org/obo/GO_0050810 regulation of steroid biosynthetic process http://purl.obolibrary.org/obo/GO_0046890 regulation of lipid biosynthetic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. http://purl.obolibrary.org/obo/GO_0050832 defense response to fungus http://purl.obolibrary.org/obo/GO_0009620 response to fungus Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. http://purl.obolibrary.org/obo/GO_0050879 multicellular organismal movement http://purl.obolibrary.org/obo/GO_0032501 multicellular organismal process Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0009894 regulation of catabolic process Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0050995 negative regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0050996 positive regulation of lipid catabolic process http://purl.obolibrary.org/obo/GO_0050994 regulation of lipid catabolic process Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. http://purl.obolibrary.org/obo/GO_0051027 DNA transport http://purl.obolibrary.org/obo/GO_0050657 nucleic acid transport The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051035 DNA transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0051032 nucleic acid transmembrane transporter activity Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_0051049 regulation of transport http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051050 positive regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051051 negative regulation of transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051055 negative regulation of lipid biosynthetic process http://purl.obolibrary.org/obo/GO_0009890 negative regulation of biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051130 positive regulation of cellular component organization http://purl.obolibrary.org/obo/GO_0048522 positive regulation of cellular process Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0042692 muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051147 regulation of muscle cell differentiation Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051154 negative regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051155 positive regulation of striated muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. http://purl.obolibrary.org/obo/GO_0051174 regulation of phosphorus metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus. http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity http://purl.obolibrary.org/obo/GO_0050790 regulation of catalytic activity Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3. http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0051451 myoblast migration http://purl.obolibrary.org/obo/GO_0014812 muscle cell migration The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers. http://purl.obolibrary.org/obo/GO_0051494 negative regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010639 negative regulation of organelle organization Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051495 positive regulation of cytoskeleton organization http://purl.obolibrary.org/obo/GO_0010638 positive regulation of organelle organization Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. http://purl.obolibrary.org/obo/GO_0051606 detection of stimulus http://purl.obolibrary.org/obo/GO_0050896 response to stimulus The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. http://purl.obolibrary.org/obo/GO_0051640 organelle localization http://purl.obolibrary.org/obo/GO_0051179 localization Any process in which an organelle is transported to, and/or maintained in, a specific location. http://purl.obolibrary.org/obo/GO_0051667 establishment of plastid localization http://purl.obolibrary.org/obo/GO_0051656 establishment of organelle localization The directed movement of a plastid to a specific location in the cell. http://purl.obolibrary.org/obo/GO_0051892 negative regulation of cardioblast differentiation http://purl.obolibrary.org/obo/GO_0051890 regulation of cardioblast differentiation Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. http://purl.obolibrary.org/obo/GO_0051937 catecholamine transport http://purl.obolibrary.org/obo/GO_0015850 organic hydroxy compound transport The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051953 negative regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051954 positive regulation of amine transport http://purl.obolibrary.org/obo/GO_0051952 regulation of amine transport Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_0051963 regulation of synapse assembly http://purl.obolibrary.org/obo/GO_1901888 regulation of cell junction assembly Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse. http://purl.obolibrary.org/obo/GO_0052547 regulation of peptidase activity http://purl.obolibrary.org/obo/GO_0051336 regulation of hydrolase activity Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins. http://purl.obolibrary.org/obo/GO_0055002 striated muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Any process that modulates the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060042 retina morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structure of the retina is generated and organized. http://purl.obolibrary.org/obo/GO_0060048 cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0006941 striated muscle contraction Muscle contraction of cardiac muscle tissue. http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060252 positive regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that activates or increases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060253 negative regulation of glial cell proliferation http://purl.obolibrary.org/obo/GO_0060251 regulation of glial cell proliferation Any process that stops or decreases the rate or extent of glial cell proliferation. http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. http://purl.obolibrary.org/obo/GO_0060491 regulation of cell projection assembly http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the rate, frequency, or extent of cell projection assembly. http://purl.obolibrary.org/obo/GO_0060537 muscle tissue development http://purl.obolibrary.org/obo/GO_0009888 tissue development The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. http://purl.obolibrary.org/obo/GO_0060627 regulation of vesicle-mediated transport http://purl.obolibrary.org/obo/GO_0051049 regulation of transport Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. http://purl.obolibrary.org/obo/GO_0060631 regulation of meiosis I http://purl.obolibrary.org/obo/GO_0040020 regulation of meiotic nuclear division Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells. http://purl.obolibrary.org/obo/GO_0061515 myeloid cell development http://purl.obolibrary.org/obo/GO_0030097 hemopoiesis The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061526 acetylcholine secretion http://purl.obolibrary.org/obo/GO_0015870 acetylcholine transport The regulated release of acetylcholine by a cell. http://purl.obolibrary.org/obo/GO_0065009 regulation of molecular function http://purl.obolibrary.org/obo/GO_0065007 biological regulation Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. http://purl.obolibrary.org/obo/GO_0070131 positive regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070507 regulation of microtubule cytoskeleton organization http://purl.obolibrary.org/obo/GO_0032886 regulation of microtubule-based process Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. http://purl.obolibrary.org/obo/GO_0070727 cellular macromolecule localization http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. http://purl.obolibrary.org/obo/GO_0071322 cellular response to carbohydrate stimulus http://purl.obolibrary.org/obo/GO_0009743 response to carbohydrate Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0002688 regulation of leukocyte chemotaxis Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0002685 regulation of leukocyte migration Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071806 protein transmembrane transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The process in which a protein is transported across a membrane. http://purl.obolibrary.org/obo/GO_0071840 cellular component organization or biogenesis http://purl.obolibrary.org/obo/GO_0009987 cellular process A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. http://purl.obolibrary.org/obo/GO_0072678 T cell migration http://purl.obolibrary.org/obo/GO_0072676 lymphocyte migration The movement of a T cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0080134 regulation of response to stress http://purl.obolibrary.org/obo/GO_0048583 regulation of response to stimulus Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization The aggregation, arrangement and bonding together of the extracellular matrix. http://purl.obolibrary.org/obo/GO_0090068 positive regulation of cell cycle process http://purl.obolibrary.org/obo/GO_0045787 positive regulation of cell cycle Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. http://purl.obolibrary.org/obo/GO_0090132 epithelium migration http://purl.obolibrary.org/obo/GO_0090130 tissue migration The process in which the population of cells that make up an epithelium undergo directed movement. http://purl.obolibrary.org/obo/GO_0098590 plasma membrane region http://purl.obolibrary.org/obo/GO_0016020 membrane A membrane that is a (regional) part of the plasma membrane. http://purl.obolibrary.org/obo/GO_0098609 cell-cell adhesion http://purl.obolibrary.org/obo/GO_0007155 cell adhesion The attachment of one cell to another cell via adhesion molecules. http://purl.obolibrary.org/obo/GO_0098636 protein complex involved in cell adhesion http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell. http://purl.obolibrary.org/obo/GO_0098722 asymmetric stem cell division http://purl.obolibrary.org/obo/GO_0017145 stem cell division Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. http://purl.obolibrary.org/obo/GO_0098878 neurotransmitter receptor complex http://purl.obolibrary.org/obo/GO_0098802 plasma membrane signaling receptor complex Any protein complex that is capable of functioning as a neurotransmitter receptor. http://purl.obolibrary.org/obo/GO_0098900 regulation of action potential http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels. http://purl.obolibrary.org/obo/GO_0099003 vesicle-mediated transport in synapse http://purl.obolibrary.org/obo/GO_0016192 vesicle-mediated transport Any vesicle-mediated transport that occurs in a synapse. http://purl.obolibrary.org/obo/GO_0099111 microtubule-based transport http://purl.obolibrary.org/obo/GO_0006810 transport A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. http://purl.obolibrary.org/obo/GO_0099528 G protein-coupled neurotransmitter receptor activity http://purl.obolibrary.org/obo/GO_0004930 G protein-coupled receptor activity Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. http://purl.obolibrary.org/obo/GO_0100001 regulation of skeletal muscle contraction by action potential http://purl.obolibrary.org/obo/GO_0014819 regulation of skeletal muscle contraction Any action potential process that regulates skeletal muscle contraction. http://purl.obolibrary.org/obo/GO_1900376 regulation of secondary metabolite biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process. http://purl.obolibrary.org/obo/GO_1901264 carbohydrate derivative transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901374 acetate ester transport http://purl.obolibrary.org/obo/GO_0006810 transport The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/GO_1901698 response to nitrogen compound http://purl.obolibrary.org/obo/GO_0042221 response to chemical Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. http://purl.obolibrary.org/obo/GO_1901861 regulation of muscle tissue development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of muscle tissue development. http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly http://purl.obolibrary.org/obo/GO_0033043 regulation of organelle organization Any process that modulates the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902116 negative regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902117 positive regulation of organelle assembly http://purl.obolibrary.org/obo/GO_1902115 regulation of organelle assembly Any process that activates or increases the frequency, rate or extent of organelle assembly. http://purl.obolibrary.org/obo/GO_1902475 L-alpha-amino acid transmembrane transport http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of L-alpha-amino acid across a membrane by means of some agent such as a transporter or a pore. http://purl.obolibrary.org/obo/GO_1902495 transmembrane transporter complex http://purl.obolibrary.org/obo/GO_1990351 transporter complex A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_0009966 regulation of signal transduction Any process that modulates the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902532 negative regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902533 positive regulation of intracellular signal transduction http://purl.obolibrary.org/obo/GO_1902531 regulation of intracellular signal transduction Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. http://purl.obolibrary.org/obo/GO_1902652 secondary alcohol metabolic process http://purl.obolibrary.org/obo/GO_0006066 alcohol metabolic process The chemical reactions and pathways involving secondary alcohol. http://purl.obolibrary.org/obo/GO_1902930 regulation of alcohol biosynthetic process http://purl.obolibrary.org/obo/GO_0009889 regulation of biosynthetic process Any process that modulates the frequency, rate or extent of alcohol biosynthetic process. http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_0051246 regulation of protein metabolic process Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903019 negative regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903020 positive regulation of glycoprotein metabolic process http://purl.obolibrary.org/obo/GO_1903018 regulation of glycoprotein metabolic process Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. http://purl.obolibrary.org/obo/GO_1903338 regulation of cell wall organization or biogenesis http://purl.obolibrary.org/obo/GO_0050794 regulation of cellular process Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis. http://purl.obolibrary.org/obo/GO_1903426 regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/GO_1903427 negative regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/GO_1903428 positive regulation of reactive oxygen species biosynthetic process http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process. http://purl.obolibrary.org/obo/GO_1903430 negative regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010721 negative regulation of cell development Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903431 positive regulation of cell maturation http://purl.obolibrary.org/obo/GO_0010720 positive regulation of cell development Any process that activates or increases the frequency, rate or extent of cell maturation. http://purl.obolibrary.org/obo/GO_1903828 negative regulation of protein localization http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. http://purl.obolibrary.org/obo/GO_1904396 regulation of neuromuscular junction development http://purl.obolibrary.org/obo/GO_0050807 regulation of synapse organization Any process that modulates the frequency, rate or extent of neuromuscular junction development. http://purl.obolibrary.org/obo/GO_1904680 peptide transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a peptide from one side of a membrane to the other. http://purl.obolibrary.org/obo/GO_1905521 regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that modulates the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/GO_1905522 negative regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/GO_1905523 positive regulation of macrophage migration http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration Any process that activates or increases the frequency, rate or extent of macrophage migration. http://purl.obolibrary.org/obo/GO_2000181 negative regulation of blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. http://purl.obolibrary.org/obo/GO_2000197 regulation of ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_0060341 regulation of cellular localization Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization. http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process http://purl.obolibrary.org/obo/GO_0050789 regulation of biological process Any process that modulates the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000242 negative regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process http://purl.obolibrary.org/obo/GO_2000241 regulation of reproductive process Any process that activates or increases the frequency, rate or extent of reproductive process. http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/GO_2000378 negative regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/GO_2000379 positive regulation of reactive oxygen species metabolic process http://purl.obolibrary.org/obo/GO_2000377 regulation of reactive oxygen species metabolic process Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process. http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000401 regulation of lymphocyte migration Any process that modulates the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/GO_2000406 positive regulation of T cell migration http://purl.obolibrary.org/obo/GO_2000404 regulation of T cell migration Any process that activates or increases the frequency, rate or extent of T cell migration. http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import http://purl.obolibrary.org/obo/GO_0015807 L-amino acid transport The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle. http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/GO_0051967 negative regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/GO_0051968 positive regulation of synaptic transmission, glutamatergic http://purl.obolibrary.org/obo/GO_0051966 regulation of synaptic transmission, glutamatergic Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate. http://purl.obolibrary.org/obo/GO_0051970 negative regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010648 negative regulation of cell communication Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0051971 positive regulation of transmission of nerve impulse http://purl.obolibrary.org/obo/GO_0010647 positive regulation of cell communication Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation. http://purl.obolibrary.org/obo/GO_0052372 modulation by symbiont of entry into host http://purl.obolibrary.org/obo/GO_0043903 regulation of biological process involved in symbiotic interaction Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0055003 cardiac myofibril assembly http://purl.obolibrary.org/obo/GO_0030239 myofibril assembly The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051146 striated muscle cell differentiation The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. http://purl.obolibrary.org/obo/GO_0055009 atrial cardiac muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0055008 cardiac muscle tissue morphogenesis The process in which the anatomical structure of cardiac atrium muscle is generated and organized. http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055019 negative regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_0055018 regulation of cardiac muscle fiber development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055020 positive regulation of cardiac muscle fiber development http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that modulates the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055022 negative regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055023 positive regulation of cardiac muscle tissue growth http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0016202 regulation of striated muscle tissue development Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055025 positive regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055026 negative regulation of cardiac muscle tissue development http://purl.obolibrary.org/obo/GO_0055024 regulation of cardiac muscle tissue development Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. http://purl.obolibrary.org/obo/GO_0055107 Golgi to secretory granule transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex. http://purl.obolibrary.org/obo/GO_0055108 Golgi to transport vesicle transport http://purl.obolibrary.org/obo/GO_0046907 intracellular transport The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. http://purl.obolibrary.org/obo/GO_0055118 negative regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060012 synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0007268 chemical synaptic transmission The vesicular release of glycine from a presynapse, across a chemical synapse, the subsequent activation of glycine receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse. http://purl.obolibrary.org/obo/GO_0060020 Bergmann glial cell differentiation http://purl.obolibrary.org/obo/GO_0048708 astrocyte differentiation The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060037 pharyngeal system development http://purl.obolibrary.org/obo/GO_0048731 system development The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the structure it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. http://purl.obolibrary.org/obo/GO_0060038 cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0014855 striated muscle cell proliferation The expansion of a cardiac muscle cell population by cell division. http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060044 negative regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060045 positive regulation of cardiac muscle cell proliferation http://purl.obolibrary.org/obo/GO_0060043 regulation of cardiac muscle cell proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0050804 modulation of chemical synaptic transmission Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0060093 negative regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0060094 positive regulation of synaptic transmission, glycinergic http://purl.obolibrary.org/obo/GO_0060092 regulation of synaptic transmission, glycinergic Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine. http://purl.obolibrary.org/obo/GO_0060096 serotonin secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0007269 neurotransmitter secretion The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0090276 regulation of peptide hormone secretion Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/GO_0060124 positive regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/GO_0060125 negative regulation of growth hormone secretion http://purl.obolibrary.org/obo/GO_0060123 regulation of growth hormone secretion Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell. http://purl.obolibrary.org/obo/GO_0060126 somatotropin secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/GO_0060127 prolactin secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. http://purl.obolibrary.org/obo/GO_0060128 corticotropin hormone secreting cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. http://purl.obolibrary.org/obo/GO_0060131 corticotropin hormone secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. http://purl.obolibrary.org/obo/GO_0060132 prolactin secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. http://purl.obolibrary.org/obo/GO_0060133 somatotropin secreting cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. http://purl.obolibrary.org/obo/GO_0060136 embryonic process involved in female pregnancy http://purl.obolibrary.org/obo/GO_0048609 multicellular organismal reproductive process A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother. http://purl.obolibrary.org/obo/GO_0060214 endocardium formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0060218 hematopoietic stem cell differentiation http://purl.obolibrary.org/obo/GO_0048863 stem cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0060221 retinal rod cell differentiation http://purl.obolibrary.org/obo/GO_0060219 camera-type eye photoreceptor cell differentiation The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. http://purl.obolibrary.org/obo/GO_0060263 regulation of respiratory burst http://purl.obolibrary.org/obo/GO_0019222 regulation of metabolic process Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. http://purl.obolibrary.org/obo/GO_0060285 cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_0001539 cilium or flagellum-dependent cell motility Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. http://purl.obolibrary.org/obo/GO_0060294 cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_0003341 cilium movement Movement of cilia mediated by motor proteins that contributes to the movement of a cell. http://purl.obolibrary.org/obo/GO_0060295 regulation of cilium movement involved in cell motility http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0110020 regulation of actomyosin structure organization Any process that modulates the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060298 positive regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that increases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060299 negative regulation of sarcomere organization http://purl.obolibrary.org/obo/GO_0060297 regulation of sarcomere organization Any process that decreases the rate, frequency or extent of myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs. http://purl.obolibrary.org/obo/GO_0060323 head morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. http://purl.obolibrary.org/obo/GO_0060324 face development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. http://purl.obolibrary.org/obo/GO_0060325 face morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which bones are generated and organized. http://purl.obolibrary.org/obo/GO_0060363 cranial suture morphogenesis http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis The process in which any suture between cranial bones is generated and organized. http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0080090 regulation of primary metabolic process Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0060409 positive regulation of acetylcholine metabolic process http://purl.obolibrary.org/obo/GO_0060408 regulation of acetylcholine metabolic process Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues. http://purl.obolibrary.org/obo/GO_0060414 aorta smooth muscle tissue morphogenesis http://purl.obolibrary.org/obo/GO_0060415 muscle tissue morphogenesis The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060421 positive regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the anatomical structures of the lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060426 lung vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. http://purl.obolibrary.org/obo/GO_0060427 lung connective tissue development http://purl.obolibrary.org/obo/GO_0061448 connective tissue development The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. http://purl.obolibrary.org/obo/GO_0060428 lung epithelium development http://purl.obolibrary.org/obo/GO_0060429 epithelium development The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. http://purl.obolibrary.org/obo/GO_0060431 primary lung bud formation http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. http://purl.obolibrary.org/obo/GO_0060433 bronchus development http://purl.obolibrary.org/obo/GO_0030323 respiratory tube development The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060434 bronchus morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060437 lung growth http://purl.obolibrary.org/obo/GO_0035265 organ growth The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. http://purl.obolibrary.org/obo/GO_0060438 trachea development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060439 trachea morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060440 trachea formation http://purl.obolibrary.org/obo/GO_0048645 animal organ formation The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. http://purl.obolibrary.org/obo/GO_0060441 epithelial tube branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0048754 branching morphogenesis of an epithelial tube The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0060452 positive regulation of cardiac muscle contraction http://purl.obolibrary.org/obo/GO_0055117 regulation of cardiac muscle contraction Any process that increases the frequency, rate or extent of cardiac muscle contraction. http://purl.obolibrary.org/obo/GO_0060457 negative regulation of digestive system process http://purl.obolibrary.org/obo/GO_0044058 regulation of digestive system process Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. http://purl.obolibrary.org/obo/GO_0060458 right lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/GO_0060459 left lung development http://purl.obolibrary.org/obo/GO_0030324 lung development The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. http://purl.obolibrary.org/obo/GO_0060460 left lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the left lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060461 right lung morphogenesis http://purl.obolibrary.org/obo/GO_0060425 lung morphogenesis The process in which anatomical structures of the right lung are generated and organized. http://purl.obolibrary.org/obo/GO_0060468 prevention of polyspermy http://purl.obolibrary.org/obo/GO_0060467 negative regulation of fertilization The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg. http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation http://purl.obolibrary.org/obo/GO_0060479 lung cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. http://purl.obolibrary.org/obo/GO_0060495 cell-cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure. http://purl.obolibrary.org/obo/GO_0060496 mesenchymal-epithelial cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung. http://purl.obolibrary.org/obo/GO_0060497 mesenchymal-endodermal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell. http://purl.obolibrary.org/obo/GO_0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. http://purl.obolibrary.org/obo/GO_0060502 epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050673 epithelial cell proliferation The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. http://purl.obolibrary.org/obo/GO_0060532 bronchus cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0060533 bronchus cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. http://purl.obolibrary.org/obo/GO_0060534 trachea cartilage development http://purl.obolibrary.org/obo/GO_0051216 cartilage development The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. http://purl.obolibrary.org/obo/GO_0060535 trachea cartilage morphogenesis http://purl.obolibrary.org/obo/GO_0060536 cartilage morphogenesis The process in which the anatomical structures of cartilage in the trachea are generated and organized. http://purl.obolibrary.org/obo/GO_0060539 diaphragm development http://purl.obolibrary.org/obo/GO_0060538 skeletal muscle organ development The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. http://purl.obolibrary.org/obo/GO_0060540 diaphragm morphogenesis http://purl.obolibrary.org/obo/GO_0048644 muscle organ morphogenesis The process in which the anatomical structures of the diaphragm are generated and organized. http://purl.obolibrary.org/obo/GO_0060572 morphogenesis of an epithelial bud http://purl.obolibrary.org/obo/GO_0060571 morphogenesis of an epithelial fold The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. http://purl.obolibrary.org/obo/GO_0060577 pulmonary vein morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. http://purl.obolibrary.org/obo/GO_0060578 superior vena cava morphogenesis http://purl.obolibrary.org/obo/GO_0048845 venous blood vessel morphogenesis The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. http://purl.obolibrary.org/obo/GO_0060591 chondroblast differentiation http://purl.obolibrary.org/obo/GO_0030154 cell differentiation The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes. http://purl.obolibrary.org/obo/GO_0060623 regulation of chromosome condensation http://purl.obolibrary.org/obo/GO_0033044 regulation of chromosome organization Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells. http://purl.obolibrary.org/obo/GO_0060638 mesenchymal-epithelial cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted. http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted. http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure http://purl.obolibrary.org/obo/GO_0051239 regulation of multicellular organismal process Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. http://purl.obolibrary.org/obo/GO_0060784 regulation of cell proliferation involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue. http://purl.obolibrary.org/obo/GO_0060785 regulation of apoptosis involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue. http://purl.obolibrary.org/obo/GO_0060786 regulation of cell differentiation involved in tissue homeostasis http://purl.obolibrary.org/obo/GO_0045595 regulation of cell differentiation Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue. http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0045446 endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/GO_0060842 arterial endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries. http://purl.obolibrary.org/obo/GO_0060843 venous endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins. http://purl.obolibrary.org/obo/GO_0060907 positive regulation of macrophage cytokine production http://purl.obolibrary.org/obo/GO_0010935 regulation of macrophage cytokine production Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. http://purl.obolibrary.org/obo/GO_0060915 mesenchymal cell differentiation involved in lung development http://purl.obolibrary.org/obo/GO_0048762 mesenchymal cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. http://purl.obolibrary.org/obo/GO_0060916 mesenchymal cell proliferation involved in lung development http://purl.obolibrary.org/obo/GO_0010463 mesenchymal cell proliferation The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation http://purl.obolibrary.org/obo/GO_0055007 cardiac muscle cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/GO_0060921 sinoatrial node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/GO_0060922 atrioventricular node cell differentiation http://purl.obolibrary.org/obo/GO_0060920 cardiac pacemaker cell differentiation The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development http://purl.obolibrary.org/obo/GO_0055013 cardiac muscle cell development The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. http://purl.obolibrary.org/obo/GO_0060928 atrioventricular node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060931 sinoatrial node cell development http://purl.obolibrary.org/obo/GO_0060926 cardiac pacemaker cell development The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. http://purl.obolibrary.org/obo/GO_0060933 His-Purkinje system cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. http://purl.obolibrary.org/obo/GO_0060935 cardiac fibroblast cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0060936 cardiac fibroblast cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules. http://purl.obolibrary.org/obo/GO_0060945 cardiac neuron differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart. http://purl.obolibrary.org/obo/GO_0060946 cardiac blood vessel endothelial cell differentiation http://purl.obolibrary.org/obo/GO_0060837 blood vessel endothelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels. http://purl.obolibrary.org/obo/GO_0060950 cardiac glial cell differentiation http://purl.obolibrary.org/obo/GO_0035051 cardiocyte differentiation The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart. http://purl.obolibrary.org/obo/GO_0060952 cardiac glial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell. http://purl.obolibrary.org/obo/GO_0060956 endocardial cell differentiation http://purl.obolibrary.org/obo/GO_0003348 cardiac endothelial cell differentiation The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0060958 endocardial cell development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. http://purl.obolibrary.org/obo/GO_0060959 cardiac neuron development http://purl.obolibrary.org/obo/GO_0055006 cardiac cell development The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state. http://purl.obolibrary.org/obo/GO_0060978 angiogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001525 angiogenesis Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0060979 vasculogenesis involved in coronary vascular morphogenesis http://purl.obolibrary.org/obo/GO_0001570 vasculogenesis The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. http://purl.obolibrary.org/obo/GO_0060980 cell migration involved in coronary vasculogenesis http://purl.obolibrary.org/obo/GO_0035441 cell migration involved in vasculogenesis The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. http://purl.obolibrary.org/obo/GO_0060981 cell migration involved in coronary angiogenesis http://purl.obolibrary.org/obo/GO_0060973 cell migration involved in heart development The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. http://purl.obolibrary.org/obo/GO_0061032 visceral serous pericardium development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. http://purl.obolibrary.org/obo/GO_0061040 female gonad morphogenesis http://purl.obolibrary.org/obo/GO_0035262 gonad morphogenesis The process in which a female gonad is generated and organized. http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0060688 regulation of morphogenesis of a branching structure Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061047 positive regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061048 negative regulation of branching involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0061046 regulation of branching involved in lung morphogenesis Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0055021 regulation of cardiac muscle tissue growth Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061051 positive regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061052 negative regulation of cell growth involved in cardiac muscle cell development http://purl.obolibrary.org/obo/GO_0061050 regulation of cell growth involved in cardiac muscle cell development Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. http://purl.obolibrary.org/obo/GO_0061054 dermatome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061055 myotome development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. http://purl.obolibrary.org/obo/GO_0061056 sclerotome development http://purl.obolibrary.org/obo/GO_0060485 mesenchyme development The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061072 iris morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. http://purl.obolibrary.org/obo/GO_0061073 ciliary body morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. http://purl.obolibrary.org/obo/GO_0061074 regulation of neural retina development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061075 positive regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061076 negative regulation of neural retina development http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. http://purl.obolibrary.org/obo/GO_0061080 right horn of sinus venosus development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the right horn of the sinus venosus from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061100 lung neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium. http://purl.obolibrary.org/obo/GO_0061101 neuroendocrine cell differentiation http://purl.obolibrary.org/obo/GO_0060563 neuroepithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. http://purl.obolibrary.org/obo/GO_0061109 dense core granule organization http://purl.obolibrary.org/obo/GO_0033363 secretory granule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells. http://purl.obolibrary.org/obo/GO_0061111 epithelial-mesenchymal cell signaling involved in lung development http://purl.obolibrary.org/obo/GO_0060684 epithelial-mesenchymal cell signaling Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ. http://purl.obolibrary.org/obo/GO_0061117 negative regulation of heart growth http://purl.obolibrary.org/obo/GO_0060420 regulation of heart growth Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. http://purl.obolibrary.org/obo/GO_0061140 lung secretory cell differentiation http://purl.obolibrary.org/obo/GO_0060487 lung epithelial cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part. http://purl.obolibrary.org/obo/GO_0061147 endocardial endothelium development http://purl.obolibrary.org/obo/GO_0003158 endothelium development The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0061148 extracellular matrix organization involved in endocardium development http://purl.obolibrary.org/obo/GO_0030198 extracellular matrix organization A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. http://purl.obolibrary.org/obo/GO_0061152 trachea submucosa development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0060562 epithelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. http://purl.obolibrary.org/obo/GO_0061155 pulmonary artery endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_0061154 endothelial tube morphogenesis The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. http://purl.obolibrary.org/obo/GO_0061156 pulmonary artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0060284 regulation of cell development Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0061182 negative regulation of chondrocyte development http://purl.obolibrary.org/obo/GO_0061181 regulation of chondrocyte development Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061184 positive regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061185 negative regulation of dermatome development http://purl.obolibrary.org/obo/GO_0061183 regulation of dermatome development Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. http://purl.obolibrary.org/obo/GO_0061189 positive regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061190 regulation of sclerotome development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. http://purl.obolibrary.org/obo/GO_0061193 taste bud development http://purl.obolibrary.org/obo/GO_0007423 sensory organ development The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/GO_0061194 taste bud morphogenesis http://purl.obolibrary.org/obo/GO_0090596 sensory organ morphogenesis The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/GO_0061195 taste bud formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. http://purl.obolibrary.org/obo/GO_0061298 retina vasculature development in camera-type eye http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the vasculature of the retina is generated and organized. http://purl.obolibrary.org/obo/GO_0061300 cerebellum vasculature development http://purl.obolibrary.org/obo/GO_0001944 vasculature development The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061301 cerebellum vasculature morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the vasculature of the cerebellum is generated and organized. http://purl.obolibrary.org/obo/GO_0061304 retinal blood vessel morphogenesis http://purl.obolibrary.org/obo/GO_0061299 retina vasculature morphogenesis in camera-type eye The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061307 cardiac neural crest cell differentiation involved in heart development http://purl.obolibrary.org/obo/GO_0014033 neural crest cell differentiation The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. http://purl.obolibrary.org/obo/GO_0061325 cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. http://purl.obolibrary.org/obo/GO_0061337 cardiac conduction http://purl.obolibrary.org/obo/GO_0008016 regulation of heart contraction Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles. http://purl.obolibrary.org/obo/GO_0061344 regulation of cell adhesion involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0030155 regulation of cell adhesion Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061385 fibroblast proliferation involved in heart morphogenesis http://purl.obolibrary.org/obo/GO_0061323 cell proliferation involved in heart morphogenesis The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. http://purl.obolibrary.org/obo/GO_0061450 trophoblast cell migration http://purl.obolibrary.org/obo/GO_0001667 ameboidal-type cell migration Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst. http://purl.obolibrary.org/obo/GO_0061484 hematopoietic stem cell homeostasis http://purl.obolibrary.org/obo/GO_0048872 homeostasis of number of cells Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells. http://purl.obolibrary.org/obo/GO_0061512 protein localization to cilium http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained in, a location within a cilium. http://purl.obolibrary.org/obo/GO_0061519 macrophage homeostasis http://purl.obolibrary.org/obo/GO_0002262 myeloid cell homeostasis The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. http://purl.obolibrary.org/obo/GO_0061523 cilium disassembly http://purl.obolibrary.org/obo/GO_1903008 organelle disassembly A cellular process that results in the breakdown of a cilium. http://purl.obolibrary.org/obo/GO_0061524 central canal development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. http://purl.obolibrary.org/obo/GO_0061527 dopamine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0099124 axonal dopamine secretion The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061533 norepinephrine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0048243 norepinephrine secretion The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061534 gamma-aminobutyric acid secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0014051 gamma-aminobutyric acid secretion The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061535 glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051938 L-glutamate import The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061536 glycine secretion http://purl.obolibrary.org/obo/GO_0015816 glycine transport The controlled release of glycine by a cell. http://purl.obolibrary.org/obo/GO_0061537 glycine secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0061536 glycine secretion The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0061548 ganglion development http://purl.obolibrary.org/obo/GO_0009888 tissue development The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061549 sympathetic ganglion development http://purl.obolibrary.org/obo/GO_0061548 ganglion development The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061551 trigeminal ganglion development http://purl.obolibrary.org/obo/GO_0061550 cranial ganglion development The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0048729 tissue morphogenesis The process in which the anatomical structures of ganglion are generated and organized. http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061554 ganglion formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061556 trigeminal ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis The process in which the anatomical structure of a trigeminal ganglion is generated and organized. http://purl.obolibrary.org/obo/GO_0061557 trigeminal ganglion maturation http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061558 cranial ganglion maturation http://purl.obolibrary.org/obo/GO_0061553 ganglion maturation A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. http://purl.obolibrary.org/obo/GO_0061559 cranial ganglion morphogenesis http://purl.obolibrary.org/obo/GO_0061552 ganglion morphogenesis The process in which the anatomical structure of a cranial ganglion is generated and organized. http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation http://purl.obolibrary.org/obo/GO_0061554 ganglion formation The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061561 trigeminal ganglion formation http://purl.obolibrary.org/obo/GO_0061560 cranial ganglion formation The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. http://purl.obolibrary.org/obo/GO_0061581 corneal epithelial cell migration http://purl.obolibrary.org/obo/GO_0010631 epithelial cell migration The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism. http://purl.obolibrary.org/obo/GO_0061626 pharyngeal arch artery morphogenesis http://purl.obolibrary.org/obo/GO_0048844 artery morphogenesis The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. http://purl.obolibrary.org/obo/GO_0061629 RNA polymerase II-specific DNA-binding transcription factor binding http://purl.obolibrary.org/obo/GO_0140297 DNA-binding transcription factor binding Binding to a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription. http://purl.obolibrary.org/obo/GO_0061650 ubiquitin-like protein conjugating enzyme activity http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another molecule, usually another protein, via the reaction X-SCP + Y = Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue. http://purl.obolibrary.org/obo/GO_0061659 ubiquitin-like protein ligase activity http://purl.obolibrary.org/obo/GO_0019787 ubiquitin-like protein transferase activity Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S = X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate. http://purl.obolibrary.org/obo/GO_0061668 mitochondrial ribosome assembly http://purl.obolibrary.org/obo/GO_0042255 ribosome assembly The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits. http://purl.obolibrary.org/obo/GO_0061725 cytosolic lipolysis http://purl.obolibrary.org/obo/GO_0016042 lipid catabolic process The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases. http://purl.obolibrary.org/obo/GO_0061736 engulfment of target by autophagosome http://purl.obolibrary.org/obo/GO_0010324 membrane invagination The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy. http://purl.obolibrary.org/obo/GO_0061792 secretory granule maturation http://purl.obolibrary.org/obo/GO_0071695 anatomical structure maturation Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodeling. http://purl.obolibrary.org/obo/GO_0070050 neuron cellular homeostasis http://purl.obolibrary.org/obo/GO_0019725 cellular homeostasis The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. http://purl.obolibrary.org/obo/GO_0070051 fibrinogen binding http://purl.obolibrary.org/obo/GO_0044877 protein-containing complex binding Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. http://purl.obolibrary.org/obo/GO_0070062 extracellular exosome http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm. http://purl.obolibrary.org/obo/GO_0070124 mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0006413 translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. http://purl.obolibrary.org/obo/GO_0070125 mitochondrial translational elongation http://purl.obolibrary.org/obo/GO_0006414 translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070126 mitochondrial translational termination http://purl.obolibrary.org/obo/GO_0006415 translational termination The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa). http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0006417 regulation of translation Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070130 negative regulation of mitochondrial translation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070129 regulation of mitochondrial translation Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070133 negative regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070134 positive regulation of mitochondrial translational initiation http://purl.obolibrary.org/obo/GO_0070132 regulation of mitochondrial translational initiation Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. http://purl.obolibrary.org/obo/GO_0070199 establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome The directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0070202 regulation of establishment of protein localization to chromosome http://purl.obolibrary.org/obo/GO_0070201 regulation of establishment of protein localization Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome. http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070228 regulation of lymphocyte apoptotic process Any process that modulates the occurrence or rate of T cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070233 negative regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070234 positive regulation of T cell apoptotic process http://purl.obolibrary.org/obo/GO_0070232 regulation of T cell apoptotic process Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process. http://purl.obolibrary.org/obo/GO_0070285 pigment cell development http://purl.obolibrary.org/obo/GO_0048468 cell development The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. http://purl.obolibrary.org/obo/GO_0070341 fat cell proliferation http://purl.obolibrary.org/obo/GO_0008283 cell population proliferation The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070345 negative regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that stops or decreases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070346 positive regulation of fat cell proliferation http://purl.obolibrary.org/obo/GO_0070344 regulation of fat cell proliferation Any process that activates or increases the rate or extent of fat cell proliferation. http://purl.obolibrary.org/obo/GO_0070444 oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0061351 neural precursor cell proliferation The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system. http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_2000177 regulation of neural precursor cell proliferation Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/GO_0070446 negative regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/GO_0070447 positive regulation of oligodendrocyte progenitor proliferation http://purl.obolibrary.org/obo/GO_0070445 regulation of oligodendrocyte progenitor proliferation Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation. http://purl.obolibrary.org/obo/GO_0070459 prolactin secretion http://purl.obolibrary.org/obo/GO_0030072 peptide hormone secretion The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary. http://purl.obolibrary.org/obo/GO_0070830 bicellular tight junction assembly http://purl.obolibrary.org/obo/GO_0120192 tight junction assembly The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. http://purl.obolibrary.org/obo/GO_0070831 basement membrane assembly http://purl.obolibrary.org/obo/GO_0085029 extracellular matrix assembly The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. http://purl.obolibrary.org/obo/GO_0071166 ribonucleoprotein complex localization http://purl.obolibrary.org/obo/GO_0051641 cellular localization Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell. http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin http://purl.obolibrary.org/obo/GO_0034502 protein localization to chromosome Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_0071169 establishment of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0071168 protein localization to chromatin The directed movement of a protein to a part of a chromosome that is organized into chromatin. http://purl.obolibrary.org/obo/GO_0071229 cellular response to acid chemical http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. http://purl.obolibrary.org/obo/GO_0071425 hematopoietic stem cell proliferation http://purl.obolibrary.org/obo/GO_0072089 stem cell proliferation The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop. http://purl.obolibrary.org/obo/GO_0071542 dopaminergic neuron differentiation http://purl.obolibrary.org/obo/GO_0030182 neuron differentiation The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. http://purl.obolibrary.org/obo/GO_0071623 negative regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071624 positive regulation of granulocyte chemotaxis http://purl.obolibrary.org/obo/GO_0071622 regulation of granulocyte chemotaxis Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071626 mastication http://purl.obolibrary.org/obo/GO_0022600 digestive system process The process of biting and mashing food with the teeth prior to swallowing. http://purl.obolibrary.org/obo/GO_0071670 smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0014909 smooth muscle cell migration The directed movement of a smooth muscle cell in response to an external stimulus. http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0014910 regulation of smooth muscle cell migration Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/GO_0071672 negative regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/GO_0071673 positive regulation of smooth muscle cell chemotaxis http://purl.obolibrary.org/obo/GO_0071671 regulation of smooth muscle cell chemotaxis Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis. http://purl.obolibrary.org/obo/CHEBI_417636 4-{((R)-2-Carboxy-3-methoxymethyl-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-7-ylcarbamoyl)-[(Z)-methoxyimino]-methyl}-thiazol-2-yl-ammonium http://purl.obolibrary.org/obo/CHEBI_33575 carboxylic acid http://purl.obolibrary.org/obo/CHEBI_35875 imidazopyrimidine http://purl.obolibrary.org/obo/CHEBI_33833 heteroarene http://purl.obolibrary.org/obo/CHEBI_35622 thiazolidines http://purl.obolibrary.org/obo/CHEBI_25693 organic heteromonocyclic compound http://purl.obolibrary.org/obo/CHEBI_48626 pyranoindolizinoquinoline http://purl.obolibrary.org/obo/CHEBI_38164 organic heteropentacyclic compound http://purl.obolibrary.org/obo/CHEBI_5530 gramicidin S http://purl.obolibrary.org/obo/CHEBI_24613 homodetic cyclic peptide http://purl.obolibrary.org/obo/CHEBI_35605 carbon oxoacid http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound http://purl.obolibrary.org/obo/CHEBI_22713 arenesulfonate oxoanion http://purl.obolibrary.org/obo/CHEBI_33554 organosulfonate oxoanion http://purl.obolibrary.org/obo/CHEBI_22495 aminobenzoic acid http://purl.obolibrary.org/obo/CHEBI_22723 benzoic acids http://purl.obolibrary.org/obo/CHEBI_38164 organic heteropentacyclic compound http://purl.obolibrary.org/obo/CHEBI_38166 organic heteropolycyclic compound http://purl.obolibrary.org/obo/CHEBI_35560 1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_38597 triazole http://purl.obolibrary.org/obo/CHEBI_7566 Nifurtimox http://purl.obolibrary.org/obo/CHEBI_87230 nitrofuran antibiotic http://purl.obolibrary.org/obo/CHEBI_38216 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) http://purl.obolibrary.org/obo/CHEBI_25471 naphthalenemonosulfonate http://purl.obolibrary.org/obo/CHEBI_49318 piperidine antibiotic http://purl.obolibrary.org/obo/CHEBI_26151 piperidines http://purl.obolibrary.org/obo/CHEBI_26833 sulfur atom http://purl.obolibrary.org/obo/CHEBI_33303 chalcogen http://purl.obolibrary.org/obo/CHEBI_36563 zinc group coordination entity http://purl.obolibrary.org/obo/CHEBI_33673 zinc group molecular entity http://purl.obolibrary.org/obo/CHEBI_35552 heterocyclic organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_33245 organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_35573 organic mancude parent http://purl.obolibrary.org/obo/CHEBI_35568 mancude ring http://purl.obolibrary.org/obo/CHEBI_35881 pnictogen hydride http://purl.obolibrary.org/obo/CHEBI_33242 inorganic hydride http://purl.obolibrary.org/obo/CHEBI_27363 zinc atom http://purl.obolibrary.org/obo/CHEBI_33340 zinc group element atom http://purl.obolibrary.org/obo/CHEBI_27364 zinc molecular entity http://purl.obolibrary.org/obo/CHEBI_33673 zinc group molecular entity http://purl.obolibrary.org/obo/CHEBI_38499 mitochondrial cytochrome-bc1 complex inhibitor http://purl.obolibrary.org/obo/CHEBI_25355 mitochondrial respiratory-chain inhibitor http://purl.obolibrary.org/obo/CHEBI_38498 mitochondrial NADH:ubiquinone reductase inhibitor http://purl.obolibrary.org/obo/CHEBI_25355 mitochondrial respiratory-chain inhibitor http://purl.obolibrary.org/obo/UBERON_0005613 left dorsal aorta http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel http://purl.obolibrary.org/obo/UBERON_0005622 right dorsal aorta http://purl.obolibrary.org/obo/UBERON_0003513 trunk blood vessel https://purl.brain-bican.org/ontology/mbao/MBA_81 lateral ventricle http://purl.obolibrary.org/obo/UBERON_0002285 telencephalic ventricle https://purl.brain-bican.org/ontology/mbao/MBA_339 Midbrain, sensory related http://purl.obolibrary.org/obo/BFO_0000004 independent continuant https://purl.brain-bican.org/ontology/mbao/MBA_987 Pons, motor related http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_29917 thiol group http://purl.obolibrary.org/obo/CHEBI_33246 inorganic group http://purl.obolibrary.org/obo/UBERON_0005282 ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system http://purl.obolibrary.org/obo/UBERON_0005726 chemosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0007037 mechanosensory system http://purl.obolibrary.org/obo/UBERON_0001032 sensory system http://purl.obolibrary.org/obo/UBERON_0009657 artery of lip http://purl.obolibrary.org/obo/UBERON_0001637 artery http://purl.obolibrary.org/obo/CHEBI_46845 N-alkylpiperazine http://purl.obolibrary.org/obo/CHEBI_50996 tertiary amino compound http://purl.obolibrary.org/obo/CHEBI_46847 N-iminopiperazine http://purl.obolibrary.org/obo/CHEBI_26144 piperazines http://purl.obolibrary.org/obo/CHEBI_94759 6-chloro-5-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole http://purl.obolibrary.org/obo/CHEBI_35618 aromatic ether http://purl.obolibrary.org/obo/CHEBI_51811 ticarcillin(2-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_52017 dicloxacillin(1-) http://purl.obolibrary.org/obo/CHEBI_51356 penicillinate anion http://purl.obolibrary.org/obo/CHEBI_36829 polyatomic monoanion http://purl.obolibrary.org/obo/CHEBI_36830 monoanion http://purl.obolibrary.org/obo/CHEBI_37826 sulfuric acid derivative http://purl.obolibrary.org/obo/CHEBI_33424 sulfur oxoacid derivative http://purl.obolibrary.org/obo/CHEBI_33366 copper group element atom http://purl.obolibrary.org/obo/CHEBI_33561 d-block element atom http://purl.obolibrary.org/obo/CHEBI_35295 homopolycyclic compound http://purl.obolibrary.org/obo/CHEBI_33635 polycyclic compound http://purl.obolibrary.org/obo/CHEBI_35427 ortho-fused polycyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33637 ortho-fused compound http://purl.obolibrary.org/obo/CHEBI_33664 monocyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_33663 cyclic hydrocarbon http://purl.obolibrary.org/obo/CHEBI_36688 heterotricyclic compound http://purl.obolibrary.org/obo/CHEBI_33671 heteropolycyclic compound http://purl.obolibrary.org/obo/NCBITaxon_1963758 Myomorpha http://purl.obolibrary.org/obo/NCBITaxon_9989 Rodentia http://purl.obolibrary.org/obo/UBERON_0009856 sac http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0018254 skeletal musculature http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure http://purl.obolibrary.org/obo/UBERON_0001726 papilla of tongue http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0002271 periventricular zone of hypothalamus http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0011159 primary subdivision of cranial skeletal system http://purl.obolibrary.org/obo/UBERON_0000075 subdivision of skeletal system https://purl.brain-bican.org/ontology/mbao/MBA_1009 fiber tracts http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0019042 reproductive system mucosa http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure http://purl.obolibrary.org/obo/UBERON_0012466 extraembryonic cavity http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0034905 gland lumen http://purl.obolibrary.org/obo/UBERON_0000464 anatomical space http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0000465 material anatomical entity http://purl.obolibrary.org/obo/UBERON_0001444 subdivision of head http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0009569 subdivision of trunk http://purl.obolibrary.org/obo/UBERON_0000475 organism subdivision http://purl.obolibrary.org/obo/UBERON_0011860 collection of collagen fibrils http://purl.obolibrary.org/obo/UBERON_0000476 acellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0005497 non-neural ectoderm http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0000479 tissue http://purl.obolibrary.org/obo/UBERON_0019304 sensory organ epithelium http://purl.obolibrary.org/obo/UBERON_0000483 epithelium http://purl.obolibrary.org/obo/UBERON_0006930 glandular cuboidal epithelium http://purl.obolibrary.org/obo/UBERON_0006799 glandular epithelium http://purl.obolibrary.org/obo/UBERON_0011272 embryonic skin basal layer http://purl.obolibrary.org/obo/UBERON_0000490 unilaminar epithelium http://purl.obolibrary.org/obo/UBERON_0011596 future lower lip http://purl.obolibrary.org/obo/UBERON_0003236 epithelium of lower jaw https://purl.brain-bican.org/ontology/mbao/MBA_688 Cerebral cortex http://purl.obolibrary.org/obo/UBERON_0000956 cerebral cortex http://purl.obolibrary.org/obo/UBERON_0034729 sympathetic nerve http://purl.obolibrary.org/obo/UBERON_0001021 nerve http://purl.obolibrary.org/obo/UBERON_0008947 respiratory primordium http://purl.obolibrary.org/obo/UBERON_0001048 primordium https://purl.brain-bican.org/ontology/mbao/MBA_56 Nucleus accumbens http://purl.obolibrary.org/obo/UBERON_0001882 nucleus accumbens https://purl.brain-bican.org/ontology/mbao/MBA_754 Olfactory tubercle http://purl.obolibrary.org/obo/UBERON_0001883 olfactory tubercle https://purl.brain-bican.org/ontology/mbao/MBA_1097 Hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0019189 carotid artery endothelium http://purl.obolibrary.org/obo/UBERON_0001917 endothelium of artery http://purl.obolibrary.org/obo/UBERON_0005844 spinal cord segment http://purl.obolibrary.org/obo/UBERON_0001948 regional part of spinal cord https://purl.brain-bican.org/ontology/mbao/MBA_315 Isocortex https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0010059 hypoglossal cord http://purl.obolibrary.org/obo/UBERON_0002036 striated muscle tissue http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/UBERON_0002049 vasculature http://purl.obolibrary.org/obo/UBERON_0003076 posterior neural tube http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0003080 anterior neural tube http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0005092 right horn of sinus venosus http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0006218 common atrial chamber http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0006260 lingual swellings http://purl.obolibrary.org/obo/UBERON_0010188 protuberance http://purl.obolibrary.org/obo/UBERON_0007237 1st arch mandibular component http://purl.obolibrary.org/obo/UBERON_0002050 embryonic structure http://purl.obolibrary.org/obo/UBERON_0010316 germ layer / neural crest http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue https://purl.brain-bican.org/ontology/mbao/MBA_398 Superior olivary complex http://purl.obolibrary.org/obo/UBERON_0002128 superior olivary complex https://purl.brain-bican.org/ontology/mbao/MBA_108 choroid plexus http://purl.obolibrary.org/obo/UBERON_0002307 choroid plexus of lateral ventricle https://purl.brain-bican.org/ontology/mbao/MBA_164 central canal, spinal cord/medulla http://purl.obolibrary.org/obo/UBERON_0002291 central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0011648 jaw muscle http://purl.obolibrary.org/obo/UBERON_0002376 cranial muscle http://purl.obolibrary.org/obo/UBERON_0019206 tongue papilla epithelium http://purl.obolibrary.org/obo/UBERON_0003357 epithelium of tongue https://purl.brain-bican.org/ontology/mbao/MBA_477 Striatum http://purl.obolibrary.org/obo/UBERON_0002435 striatum http://purl.obolibrary.org/obo/UBERON_0016527 white matter of cerebral lobe http://purl.obolibrary.org/obo/UBERON_0002437 cerebral hemisphere white matter https://purl.brain-bican.org/ontology/mbao/MBA_1022 Globus pallidus, external segment http://purl.obolibrary.org/obo/UBERON_0002476 lateral globus pallidus http://purl.obolibrary.org/obo/UBERON_0002558 organ cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0011565 lumen of gastrointestinal system http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity https://purl.brain-bican.org/ontology/mbao/MBA_698 Olfactory areas https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0007690 early pharyngeal endoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0013156 1st arch mandibular endoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue http://purl.obolibrary.org/obo/UBERON_0019263 gray matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0019267 gray matter of midbrain http://purl.obolibrary.org/obo/UBERON_0003528 brain gray matter http://purl.obolibrary.org/obo/UBERON_0009644 trachea non-cartilage connective tissue http://purl.obolibrary.org/obo/UBERON_0003571 trachea connective tissue http://purl.obolibrary.org/obo/UBERON_0011766 left recurrent laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0011767 right recurrent laryngeal nerve http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure http://purl.obolibrary.org/obo/UBERON_0006304 future trigeminal ganglion http://purl.obolibrary.org/obo/UBERON_0003869 presumptive ganglion https://purl.brain-bican.org/ontology/mbao/MBA_703 Cortical subplate http://purl.obolibrary.org/obo/UBERON_0004035 cortical subplate http://purl.obolibrary.org/obo/UBERON_0013160 epithalamus ventricular layer http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer http://purl.obolibrary.org/obo/UBERON_0034710 spinal cord ventricular layer http://purl.obolibrary.org/obo/UBERON_0004060 neural tube ventricular layer http://purl.obolibrary.org/obo/UBERON_0009580 diencephalon mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0009581 midbrain mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0009583 spinal cord mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0013159 epithalamus mantle layer http://purl.obolibrary.org/obo/UBERON_0004061 neural tube mantle layer http://purl.obolibrary.org/obo/UBERON_0034709 hindbrain marginal layer http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0005239 basal plate metencephalon http://purl.obolibrary.org/obo/UBERON_0004064 neural tube basal plate http://purl.obolibrary.org/obo/UBERON_0005728 extraembryonic mesoderm http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue http://purl.obolibrary.org/obo/UBERON_0009615 midbrain hindbrain boundary neural plate http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0005339 outflow tract pulmonary component http://purl.obolibrary.org/obo/UBERON_0004145 outflow tract http://purl.obolibrary.org/obo/UBERON_0009196 indifferent external genitalia http://purl.obolibrary.org/obo/UBERON_0004176 external genitalia http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle http://purl.obolibrary.org/obo/UBERON_0004277 eye muscle http://purl.obolibrary.org/obo/UBERON_0012416 respiratory system arterial smooth muscle http://purl.obolibrary.org/obo/UBERON_0004695 arterial system smooth muscle http://purl.obolibrary.org/obo/UBERON_0018649 cardiac muscle tissue of ventricle http://purl.obolibrary.org/obo/UBERON_0004493 cardiac muscle tissue of myocardium http://purl.obolibrary.org/obo/UBERON_2001053 future internal carotid artery http://purl.obolibrary.org/obo/UBERON_0004573 systemic artery http://purl.obolibrary.org/obo/UBERON_0008339 microvascular endothelium http://purl.obolibrary.org/obo/UBERON_0004638 blood vessel endothelium http://purl.obolibrary.org/obo/UBERON_0010291 layer of sclera http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0011234 fibrous membrane of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0004923 organ component layer http://purl.obolibrary.org/obo/UBERON_0015410 heart plus pericardium http://purl.obolibrary.org/obo/UBERON_0005178 thoracic cavity element http://purl.obolibrary.org/obo/UBERON_0009920 optic neural crest http://purl.obolibrary.org/obo/UBERON_0007530 migrating mesenchyme population http://purl.obolibrary.org/obo/UBERON_0009618 trunk paraxial mesoderm http://purl.obolibrary.org/obo/UBERON_0005256 trunk mesenchyme http://purl.obolibrary.org/obo/UBERON_0009722 entire pharyngeal arch endoderm http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0009881 anterior lateral plate mesoderm http://purl.obolibrary.org/obo/UBERON_0005291 embryonic tissue https://purl.brain-bican.org/ontology/mbao/MBA_695 Cortical plate http://purl.obolibrary.org/obo/UBERON_0005343 cortical plate https://purl.brain-bican.org/ontology/mbao/MBA_485 Striatum dorsal region http://purl.obolibrary.org/obo/UBERON_0005382 dorsal striatum https://purl.brain-bican.org/ontology/mbao/MBA_672 Caudoputamen http://purl.obolibrary.org/obo/UBERON_0005383 caudate-putamen https://purl.brain-bican.org/ontology/mbao/MBA_493 Striatum ventral region http://purl.obolibrary.org/obo/UBERON_0005403 ventral striatum http://purl.obolibrary.org/obo/UBERON_0009145 pharyngeal region of foregut http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0014950 layer of developing cerebral cortex http://purl.obolibrary.org/obo/UBERON_0005423 developing anatomical structure http://purl.obolibrary.org/obo/UBERON_0022248 cerebral nerve fasciculus http://purl.obolibrary.org/obo/UBERON_0005838 fasciculus of brain http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/UBERON_0005856 developing mesenchymal condensation http://purl.obolibrary.org/obo/UBERON_0011332 extrinsic tongue pre-muscle mass http://purl.obolibrary.org/obo/UBERON_0005865 pre-muscle condensation http://purl.obolibrary.org/obo/UBERON_0010213 laryngeal pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0005866 pre-cartilage condensation http://purl.obolibrary.org/obo/UBERON_0006136 unmyelinated nerve fiber http://purl.obolibrary.org/obo/UBERON_0006134 nerve fiber https://purl.brain-bican.org/ontology/mbao/MBA_803 Pallidum http://purl.obolibrary.org/obo/UBERON_0011300 gray matter of telencephalon https://purl.brain-bican.org/ontology/mbao/MBA_818 Pallidum, dorsal region https://purl.brain-bican.org/ontology/mbao/MBA_803 Pallidum http://purl.obolibrary.org/obo/UBERON_0006241 future spinal cord http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0006596 presumptive blood http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0007026 presumptive gut http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0034875 future pituitary gland http://purl.obolibrary.org/obo/UBERON_0006598 presumptive structure http://purl.obolibrary.org/obo/UBERON_0015128 subepicardial layer of epicardium http://purl.obolibrary.org/obo/UBERON_0007188 mesothelium of serous pericardium http://purl.obolibrary.org/obo/UBERON_0010221 laryngeal associated mesenchyme http://purl.obolibrary.org/obo/UBERON_0007524 dense mesenchyme tissue https://purl.brain-bican.org/ontology/mbao/MBA_997 brain http://purl.obolibrary.org/obo/UBERON_0008823 neural tube derived brain http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle http://purl.obolibrary.org/obo/UBERON_0010000 multicellular anatomical structure http://purl.obolibrary.org/obo/UBERON_0010528 pneumatic cavity of bone http://purl.obolibrary.org/obo/UBERON_0010527 cavity of bone organ http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0016550 spinal cord column http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster http://purl.obolibrary.org/obo/UBERON_0016570 lamina of gray matter of spinal cord http://purl.obolibrary.org/obo/UBERON_0022303 nervous system cell part layer http://purl.obolibrary.org/obo/UBERON_0010191 aortic system http://purl.obolibrary.org/obo/UBERON_0011216 organ system subdivision http://purl.obolibrary.org/obo/UBERON_0001606 muscle of iris http://purl.obolibrary.org/obo/UBERON_0011222 intra-ocular muscle http://purl.obolibrary.org/obo/UBERON_0005434 cervical region http://purl.obolibrary.org/obo/UBERON_0011676 subdivision of organism along main body axis http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0011822 dense irregular connective tissue http://purl.obolibrary.org/obo/UBERON_0018135 fibrocollagenous connective tissue http://purl.obolibrary.org/obo/UBERON_0011824 fibrous connective tissue http://purl.obolibrary.org/obo/UBERON_0009676 early telencephalic vesicle http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle http://purl.obolibrary.org/obo/UBERON_0013149 hindbrain vesicle http://purl.obolibrary.org/obo/UBERON_0013150 future brain vesicle http://purl.obolibrary.org/obo/UBERON_0014531 white matter lamina of diencephalon http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis http://purl.obolibrary.org/obo/UBERON_0014532 white matter lamina of cerebral hemisphere http://purl.obolibrary.org/obo/UBERON_0014530 white matter lamina of neuraxis http://purl.obolibrary.org/obo/UBERON_0019292 white matter of pons http://purl.obolibrary.org/obo/UBERON_0019291 white matter of metencephalon http://purl.obolibrary.org/obo/UBERON_0034769 lymphomyeloid tissue http://purl.obolibrary.org/obo/UBERON_0015757 heterogeneous tissue http://purl.obolibrary.org/obo/UBERON_0019291 white matter of metencephalon http://purl.obolibrary.org/obo/UBERON_0019258 white matter of hindbrain http://purl.obolibrary.org/obo/UBERON_0019269 gray matter of diencephalon http://purl.obolibrary.org/obo/UBERON_0019264 gray matter of forebrain http://purl.obolibrary.org/obo/UBERON_0019293 white matter of pontine tegmentum http://purl.obolibrary.org/obo/UBERON_0019292 white matter of pons http://purl.obolibrary.org/obo/UBERON_0025736 chemoarchitectural part of striatum http://purl.obolibrary.org/obo/UBERON_0024090 chemoarchitectural part of brain http://purl.obolibrary.org/obo/UBERON_0029002 matrix compartment of putamen http://purl.obolibrary.org/obo/UBERON_0027368 matrix compartment http://purl.obolibrary.org/obo/UBERON_0029004 striosomal part of caudate nucleus http://purl.obolibrary.org/obo/UBERON_0027371 striosome http://purl.obolibrary.org/obo/UBERON_0029005 striosomal part of putamen http://purl.obolibrary.org/obo/UBERON_0027371 striosome http://purl.obolibrary.org/obo/UBERON_0034708 cerebellum marginal layer http://purl.obolibrary.org/obo/UBERON_0034709 hindbrain marginal layer http://purl.obolibrary.org/obo/UBERON_0006056 posterior surface of head http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/UBERON_0022288 surface of eyeball http://purl.obolibrary.org/obo/UBERON_0036215 anatomical surface region http://purl.obolibrary.org/obo/CHEBI_10642 scyllo-inositol http://purl.obolibrary.org/obo/CHEBI_24848 inositol http://purl.obolibrary.org/obo/CHEBI_35571 mancude organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_35573 organic mancude parent http://purl.obolibrary.org/obo/CHEBI_36388 saturated organic heterocyclic parent http://purl.obolibrary.org/obo/CHEBI_35552 heterocyclic organic fundamental parent http://purl.obolibrary.org/obo/CHEBI_35550 1H-1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_35560 1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_35561 3H-1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_35560 1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_46077 4H-1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_35560 1,2,4-triazole http://purl.obolibrary.org/obo/CHEBI_36623 4H-benzimidazole http://purl.obolibrary.org/obo/CHEBI_36622 benzimidazole http://purl.obolibrary.org/obo/CHEBI_36639 2H-benzimidazole http://purl.obolibrary.org/obo/CHEBI_36622 benzimidazole http://purl.obolibrary.org/obo/CHEBI_36641 3aH-benzimidazole http://purl.obolibrary.org/obo/CHEBI_36622 benzimidazole http://purl.obolibrary.org/obo/UBERON_0036303 vasculature of central nervous system http://purl.obolibrary.org/obo/UBERON_0036302 vasculature of central nervous system plus retina http://purl.obolibrary.org/obo/CHEBI_50906 role A role is particular behaviour which a material entity may exhibit. http://purl.obolibrary.org/obo/PHIPO_0000005 obsolete abnormal pathogenicity A phenotype where the pathogenicity is abnormal (i.e different than wild-type) http://purl.obolibrary.org/obo/PHIPO_0000007 obsolete functional pathogen effector absent A phenotype where the ability of a pathogen effector to produce an infectious disease is absent. http://purl.obolibrary.org/obo/PHIPO_0000008 obsolete functional pathogen effector present A phenotype where the ability of a pathogen effector to produce an infectious disease is present. http://purl.obolibrary.org/obo/PHIPO_0000013 obsolete abnormal virulence A phenotype where virulence is abnormal (i.e. different than wild-type). http://purl.obolibrary.org/obo/PHIPO_0000023 obsolete abnormal penetration assay phenotype A pathogen penetration assay phenotype (assessing the organism's ability to penetrate a given substance/membrane) which is abnormal (i.e. different than wild-type). http://purl.obolibrary.org/obo/PHIPO_0000026 obsolete normal penetration A pathogen phenotype indicating that the pathogen is able to penetrate a given experimental substance/membrane in the same manner as the wild-type. http://purl.obolibrary.org/obo/PHIPO_0000033 obsolete abnormal pathogen growth on host surface A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001099 obsolete increased RNA level in a pathogen host interaction A cell phenotype in which the amount of RNA measured in a pathogen or host cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0001109 obsolete abnormal pathogen-induced host pH A pathogen host interaction phenotype, in which the host pH value during infection differs from normal. http://purl.obolibrary.org/obo/PHIPO_0001110 obsolete pathogen-induced decrease in host pH A pathogen host interaction phenotype where the pathogen induces a pH decrease within the host cell or cellular component. http://purl.obolibrary.org/obo/PHIPO_0001111 obsolete pathogen-induced increase in host pH A pathogen host interaction phenotype where the pathogen induces a pH increase within the host cell or cellular component. http://purl.obolibrary.org/obo/PHIPO_0001112 obsolete normal pH within a pathogen host interaction A pathogen host interaction phenotype where the pH in a pathogen or host cell or cellular component is normal. http://purl.obolibrary.org/obo/PHIPO_0001201 obsolete pathogen effector phenotype A phenotype that is relevant to pathogen effectors. http://purl.obolibrary.org/obo/PHIPO_0001202 obsolete loss of functional pathogen effector A phenotype where the ability of a pathogen effector to produce an infectious disease is abolished. http://purl.obolibrary.org/obo/PHIPO_0001203 obsolete gain of functional pathogen effector A phenotype where the ability of a pathogen effector to produce an infectious disease is acquired. http://purl.obolibrary.org/obo/CHEBI_36342 subatomic particle A particle smaller than an atom. http://purl.obolibrary.org/obo/GO_0044464 obsolete cell part OBSOLETE. Any constituent part of a cell, the basic structural and functional unit of all organisms. http://purl.obolibrary.org/obo/UBERON_0000000 processual entity An occurrent [span:Occurrent] that exists in time by occurring or happening, has temporal parts and always involves and depends on some entity. http://purl.obolibrary.org/obo/PHIPO_0000113 obsolete altered functionality of penetration structure Penetration structure formed but not functioning in the same manner as the wild type. http://purl.obolibrary.org/obo/PHIPO_0000167 obsolete pathogen host interaction RNA binding phenotype A pathogen host interaction phenotype that affects RNA binding. The relevant gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000168 obsolete abnormal pathogen host interaction RNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is abnormal, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000171 obsolete normal pathogen host interaction RNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000172 obsolete abolished pathogen host interaction RNA binding A pathogen host interaction (molecular function??) phenotype in which RNA binding by a gene product does not occur, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000174 obsolete decreased pathogen host interaction RNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is decreased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000175 obsolete normal pathogen growth on host surface A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is normal. http://purl.obolibrary.org/obo/PHIPO_0000176 obsolete increased pathogen host interaction RNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of RNA binding by a gene product is increased, when a gene or the bound RNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000177 obsolete yeast-form growth phenotype A single species population phenotype in which affects the population growth during the yeast-form lifecycle stage. http://purl.obolibrary.org/obo/PHIPO_0000178 obsolete pathogen host interaction DNA binding phenotype A pathogen host interaction phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000180 obsolete abnormal pathogen host interaction DNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000183 obsolete normal pathogen host interaction DNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000185 obsolete abnormal pathogen host interaction multiple protein binding to DNA A pathogen host interaction (molecular function??) phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000187 obsolete abolished pathogen host interaction DNA binding A pathogen host interaction (molecular function??) phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000189 obsolete altered pathogen host interaction DNA binding specificity A pathogen host interaction (molecular function??) phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000191 obsolete decreased pathogen host interaction DNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000193 obsolete increased pathogen host interaction DNA binding A pathogen host interaction (molecular function??) phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000197 obsolete abnormal pathogen host protein protein interaction A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000198 obsolete pathogen host interaction transporter phenotype A pathogen host interaction phenotype which affects a transporter activity. http://purl.obolibrary.org/obo/PHIPO_0000199 obsolete normal pathogen host protein protein interaction A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. http://purl.obolibrary.org/obo/PHIPO_0000201 obsolete normal pathogen host protein complex binding A pathogen (molecular function??) phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000202 obsolete abnormal pathogen host protein complex binding A pathogen host interaction (molecular function??) phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene. http://purl.obolibrary.org/obo/PHIPO_0000203 obsolete increased aerial height of filamentous colony affecting colony shape A single species hyphal colony shape phenotype where the aerial height of the filamentous colony is increased. http://purl.obolibrary.org/obo/PHIPO_0000206 obsolete altered pathogen and host protein binding specificity A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs with a different specificity than normal. http://purl.obolibrary.org/obo/PHIPO_0000208 obsolete decreased duration of pathogen host protein-protein interaction A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs for a shorter time than normal. http://purl.obolibrary.org/obo/PHIPO_0000210 obsolete decreased extent and duration of pathogen host protein-protein interaction A molecular function phenotype in which the binding of one pathogen protein to one host protein occurs to a lower extent, and for a shorter time, than normal. http://purl.obolibrary.org/obo/PHIPO_0000217 obsolete pathogen host interaction primary metabolic process phenotype A pathogen host interaction phenotype that affects the chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. http://purl.obolibrary.org/obo/PHIPO_0000218 obsolete abnormal pathogen host interaction toxin biosynthetic process A pathogen host interaction phenotype in which the toxin biosynthetic process is abnormal (i.e. different than the wild type). http://purl.obolibrary.org/obo/PHIPO_0000220 obsolete pathogen host interaction metabolic process phenotype A pathogen host interaction phenotype that affects the chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. http://purl.obolibrary.org/obo/PHIPO_0000226 obsolete pathogen host interaction secondary metabolite biosynthetic process phenotype A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. http://purl.obolibrary.org/obo/PHIPO_0000227 obsolete pathogen host interaction secondary metabolic process phenotype A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. http://purl.obolibrary.org/obo/PHIPO_0000228 obsolete normal pathogen host interaction biosynthesis of deoxynivalenol A pathogen host interaction phenotype in which the pathogen biosynthesis of deoxynivalenol is normal (i.e. same as the wild type). http://purl.obolibrary.org/obo/PHIPO_0000229 obsolete abnormal pathogen host interaction biosynthesis of deoxynivalenol A pathogen host interaction phenotype in which the pathogen biosynthesis of deoxynivalenol is abnormal (i.e. different than the wild type). http://purl.obolibrary.org/obo/PHIPO_0000230 obsolete normal pathogen host interaction toxin biosynthetic process A pathogen host interaction phenotype in which the toxin biosynthetic process is normal (i.e. same as the wild type). http://purl.obolibrary.org/obo/PHIPO_0000231 obsolete pathogen host interaction toxin biosynthetic process phenotype A pathogen host interaction phenotype that affects the chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism. http://purl.obolibrary.org/obo/PHIPO_0000238 obsolete pathogen host interaction protein localization phenotype A pathogen host interaction phenotype that affects the localization of a protein in a cell. http://purl.obolibrary.org/obo/PHIPO_0000242 obsolete abnormal pathogen host interaction protein complex localization A pathogen host interaction phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000243 obsolete abnormal pathogen host interaction protein localization to nucleus A pathogen host interaction phenotype in which the localization of a protein to the nucleus is abnormal. (Which nucleus? pathogen or host?) http://purl.obolibrary.org/obo/PHIPO_0000250 obsolete pathogen host interaction RNA localization phenotype A pathogen host interaction phenotype that affects the localization of an RNA in a cell. http://purl.obolibrary.org/obo/PHIPO_0000252 obsolete abnormal pathogen host interaction RNA localization A pathogen host interaction phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. http://purl.obolibrary.org/obo/PHIPO_0000254 obsolete normal pathogen host interaction RNA localization A pathogen host interaction phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000255 obsolete pathogen host interaction transport phenotype A pathogen host interaction (cell process???) phenotype that affects a transport process. http://purl.obolibrary.org/obo/PHIPO_0000258 obsolete abnormal pathogen host interaction transport A pathogen host interaction phenotype in which a specific transport process is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000260 obsolete normal pathogen host interaction protein transport A pathogen host interaction (cellular process??) phenotype in which protein transport is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000262 obsolete abnormal pathogen host interaction endocytosis A pathogen host interaction (cellular process???) phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. http://purl.obolibrary.org/obo/PHIPO_0000264 obsolete abnormal pathogen host interaction nuclear transport A pathogen host interaction (cellular process??) phenotype in which nuclear transport is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000266 obsolete abnormal pathogen host interaction protein transport A pathogen host interaction (cellular process??) phenotype in which protein transport is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000268 obsolete abnormal pathogen host interaction vacuolar transport A pathogen host interaction (cellular process??) phenotype in which vacuolar transport is abnormal. http://purl.obolibrary.org/obo/PHIPO_0000305 obsolete effector of pathogenicity phenotype (Required for successful infection of the host species). The ability of an organism to activate or suppress host defenses to enable infectious disease. (Irrespective of the host genotype). http://purl.obolibrary.org/obo/PHIPO_0000306 obsolete abnormal effector of virulence The host defenses activated by the pathogen are altered compared to the wild type interaction http://purl.obolibrary.org/obo/PHIPO_0000307 obsolete normal effector of pathogenicity The ability to cause disease by activating or suppressing host defenses is unaltered compared to the wildtype interaction. This may result in the outcome of being pathogenic or not-pathogenic. http://purl.obolibrary.org/obo/PHIPO_0000308 obsolete normal effector of pathogenicity activation of host defense The host defenses activated by the pathogen are unaltered compared to the wild type interaction http://purl.obolibrary.org/obo/PHIPO_0000309 obsolete normal effector of pathogenicity suppression of host defense The host defenses suppressed by the pathogen are unaltered compared to the wild type interaction http://purl.obolibrary.org/obo/PHIPO_0000310 obsolete normal effector of virulence The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype and this is unaltered compared to the wildtype interaction. This may result in disease (virulence) or no disease (avirulence). http://purl.obolibrary.org/obo/PHIPO_0000311 obsolete effector of virulence phenotype (gene for gene relationships) or defined from the phenotype described in the published study. The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype. http://purl.obolibrary.org/obo/PHIPO_0000312 obsolete abnormal effector of pathogenicity The ability to cause disease by activating or suppressing host defenses is altered compared to the wildtype interaction. http://purl.obolibrary.org/obo/PHIPO_0000313 obsolete normal effector of virulence activation of host defense The host defenses activated by the pathogen are unaltered compared to the wild type interaction http://purl.obolibrary.org/obo/PHIPO_0000314 obsolete normal effector of virulence suppression of host defense The host defenses suppressed by the pathogen are unaltered compared to the wild type interaction http://purl.obolibrary.org/obo/PHIPO_0000315 obsolete abnormal effector of virulence activation of host defense The pathogen has the ability to cause infectious disease dependent upon the gene for gene relationship between the pathogen and host genotype and this is altered compared to the wildtype interaction. This may result in disease (virulence) or no disease (avirulence). http://purl.obolibrary.org/obo/PHIPO_0000316 obsolete decreased effector of virulence activation of host defense The pathogen effector entity has a decreased ability to activate host defense. http://purl.obolibrary.org/obo/PHIPO_0000317 obsolete increased effector of virulence activation of host defense The pathogen effector entity has an increased ability to activate host defense. http://purl.obolibrary.org/obo/PHIPO_0000318 obsolete abnormal effector of virulence suppression of host defense The host defenses suppressed by the pathogen are altered compare to the wild type interaction http://purl.obolibrary.org/obo/PHIPO_0000319 obsolete decreased effector of virulence suppression of host defense The pathogen effector entity has a decreased ability to suppress host defense. http://purl.obolibrary.org/obo/PHIPO_0000320 obsolete increased effector of virulence suppression of host defense The pathogen effector entity has an increased ability to suppress host defense. http://purl.obolibrary.org/obo/PHIPO_0000321 obsolete abnormal effector of pathogenicity activation of host defense The host defenses activated by the pathogen are altered compared to the wild type interaction. http://purl.obolibrary.org/obo/PHIPO_0000322 obsolete gain of effector of pathogenicity activation of host defense The pathogen effector entity has gained the ability to activate host defense. http://purl.obolibrary.org/obo/PHIPO_0000323 obsolete loss of effector of pathogenicity activation of host defense The pathogen effector entity has lost the ability to activate host defense. http://purl.obolibrary.org/obo/PHIPO_0000324 obsolete abnormal effector of pathogenicity suppression of host defense The host defenses suppressed by the pathogen are altered compared to the wild type interaction http://purl.obolibrary.org/obo/PHIPO_0000325 obsolete gain of effector of pathogenicity suppression of host defense The pathogen effector entity has gained the ability to suppress host defense. http://purl.obolibrary.org/obo/PHIPO_0000326 obsolete loss of effector of pathogenicity suppression of host defense The pathogen effector entity has lost the ability to suppress host defense. http://purl.obolibrary.org/obo/PHIPO_0000341 obsolete gain of pathogen cell to cell migration within host A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally within the host organism is gained (pathogen migration was absent within the host and is now present). http://purl.obolibrary.org/obo/PHIPO_0000348 obsolete pathogen host interaction catalytic activity phenotype A pathogen host interaction phenotype which affects a catalytic activity. http://purl.obolibrary.org/obo/PHIPO_0000351 obsolete pathogen is able to penetrate host A pathogen growth with host phenotype in which the pathogen is able to penetrate the host. http://purl.obolibrary.org/obo/PHIPO_0000353 obsolete normal penetration of host by pathogen A pathogen growth with host phenotype in which the pathogen penetration into the host is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000356 obsolete abnormal penetration of host by pathogen A pathogen growth with host phenotype in which the pathogen penetration into the host is abnormal (i.e different than wild-type). http://purl.obolibrary.org/obo/PHIPO_0000358 obsolete non-functional pathogen penetration structure in contact with host A pathogen growth with host phenotype in which the pathogen forms a non-functional specialized penetration structure. http://purl.obolibrary.org/obo/PHIPO_0000364 obsolete abnormal pathogen growth within host A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is abnormal (i.e different than wild type). http://purl.obolibrary.org/obo/PHIPO_0000370 obsolete pathogen penetration structure absent when near host A pathogen growth with host phenotype in which the pathogen specialized host penetration structure is absent. http://purl.obolibrary.org/obo/PHIPO_0000425 obsolete pathogen host interaction pathogen carbohydrate binding phenotype A pathogen host interaction phenotype which affects the binding of carbohydrate to protein. http://purl.obolibrary.org/obo/PHIPO_0000426 obsolete presence of pathogen chitinase binding to pathogen chitin fragments within host interaction A molecular function phenotype in which the binding of pathogen chitinase to pathogen chitin fragments generated within a host interaction is present. http://purl.obolibrary.org/obo/PHIPO_0000427 obsolete pathogen chitin binding to host chitinase present A molecular function phenotype in which the binding of pathogen chitin to host chitinase is present. http://purl.obolibrary.org/obo/PHIPO_0000464 obsolete host necrotic cell death phenotype in response to pathogen A phenotype affecting the process of host tissue cell death caused by the pathogen (GO:0097300 part of GO:0009608 ). http://purl.obolibrary.org/obo/PHIPO_0000466 obsolete host necrotic cell death by pathogen induced hypersensitive response A phenotype that affects the immune system process of host necrotic cell death by pathogen induced hypersensitive response. Pathogen induced hypersensitive response is the rapid, localized death of plant cells in response to invasion by a pathogen (GO:0009626). http://purl.obolibrary.org/obo/PHIPO_0000483 obsolete normal pathogen host interaction phenotype A pathogen host interaction phenotype which is normal (i.e. the same as wild-type). http://purl.obolibrary.org/obo/PHIPO_0000484 obsolete abnormal pathogen host interaction phenotype A pathogen host interaction phenotype which is abnormal (i.e. different than wild-type). http://purl.obolibrary.org/obo/PHIPO_0000499 obsolete normal synthesis of deoxynivalenol A single organism phenotype in which the biosynthesis of deoxynivalenol is normal (i.e. same as the wild type). http://purl.obolibrary.org/obo/PHIPO_0000500 obsolete abnormal biosynthesis of deoxynivalenol A single organism phenotype in which the biosynthesis of deoxynivalenol is abnormal (i.e. different than the wild type). http://purl.obolibrary.org/obo/PHIPO_0000501 obsolete increased level of deoxynivalenol A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0000502 obsolete decreased level of deoxynivalenol A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0000503 obsolete deoxynivalenol absent from cell A single organism cell phenotype in which the amount of deoxynivalenol measured in a cell is too low to detect. http://purl.obolibrary.org/obo/PHIPO_0000504 obsolete deoxynivalenol present A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000505 phenotype Any of the set of observable characteristics of an organism resulting from the interaction of its genotype with the environment. http://purl.obolibrary.org/obo/PHIPO_0000511 obsolete pathogen host interaction cell population phenotype A pathogen host interaction phenotype that is observed at the level of a population of cells. http://purl.obolibrary.org/obo/PHIPO_0000512 obsolete pathogen host interaction host tissue phenotype A pathogen host interaction phenotype that is observed at the level of a host tissue (eg leaf, inflorescence, ear or kidney). http://purl.obolibrary.org/obo/PHIPO_0000987 obsolete altered level of substance phenotype in a pathogen host interaction A cell phenotype in which the amount of a specific substance measured in a cell within a pathogen host interaction differs from normal. http://purl.obolibrary.org/obo/PHIPO_0000988 obsolete altered protein level in a pathogen host interaction A cell phenotype in which the amount of protein measured in a pathogen or host cell differs from normal. Total protein or a specific protein may be affected. http://purl.obolibrary.org/obo/PHIPO_0000990 obsolete absence of pathogen protein with host A pathogen host interaction phenotype, in which the pathogen produced protein usually present during infection is absent. http://purl.obolibrary.org/obo/PHIPO_0000993 obsolete altered RNA level in a pathogen host interaction A cell phenotype in which the amount of RNA measured in a pathogen or host cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0000994 obsolete decreased RNA level in a pathogen host interaction A cell phenotype in which the amount of RNA measured in a pathogen or host cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. http://purl.obolibrary.org/obo/PHIPO_0001007 obsolete pathogen colonization of host morphology phenotype A pathogen host interaction phenotype which affects the morphology of the pathogen or the host during pathogen colonization of the host. This relates to the pathogen colonization of the body, tissues, or cells of the host organism. http://purl.obolibrary.org/obo/PHIPO_0001012 obsolete pathogen host interaction polysaccharide localization phenotype A pathogen host interaction phenotype which affects the localization of a polysaccharide in a pathogen or host cell is abnormal. This includes any process in which a polysaccharide is transported to, or maintained in, a specific location. (GO:0033037). http://purl.obolibrary.org/obo/PHIPO_0001013 obsolete abnormal pathogen host interaction polysaccharide localization A pathogen host interaction phenotype in which the localization of a polysaccharide in a pathogen or host cell is abnormal. This includes any process in which a polysaccharide is transported to, or maintained in, a specific location. (GO:0033037). http://purl.obolibrary.org/obo/PHIPO_0001016 obsolete altered level of host callose deposition induced by pathogen A pathogen host interaction phenotype where any process in which callose is transported to, and/or maintained in, a specific location during the host defense response to a pathogen is abnormal. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. (GO:0052542). http://purl.obolibrary.org/obo/PHIPO_0001040 obsolete decreased level of a substance in a pathogen host interaction A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001041 obsolete increased level of a substance in a pathogen host interaction A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001042 obsolete substance absent in a pathogen host interaction A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is too low to detect. http://purl.obolibrary.org/obo/PHIPO_0001044 obsolete protein absent in a pathogen host interaction A cell phenotype in which the amount of protein measured in a pathogen or host cell is too low to detect. Total protein or a specific protein may be affected. http://purl.obolibrary.org/obo/PHIPO_0001048 obsolete normal level of substance phenotype in a pathogen host interaction A cell phenotype in which the amount of a specific substance measured in a pathogen or host cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001055 obsolete increased size of colony A single species colony morphology phenotype where the size of the population is increased. http://purl.obolibrary.org/obo/PHIPO_0001067 obsolete pathogen host interaction organism level phenotype A pathogen host interaction phenotype that is observed at the level of an individual organism (eg a worm host). http://purl.obolibrary.org/obo/PHIPO_0001071 obsolete viable host organism with pathogen A pathogen host interaction organism viability phenotype where a host organism is viable in the presence of a pathogen. http://purl.obolibrary.org/obo/PHIPO_0001072 obsolete inviable host organism with pathogen A pathogen host interaction organism viability phenotype where a host organism is inviable in the presence of a pathogen. http://purl.obolibrary.org/obo/PHIPO_0001079 obsolete pathogen host interaction pigment phenotype A pathogen host interaction organism level phenotype affecting the deposition or aggregation of coloring matter in a cell. http://purl.obolibrary.org/obo/PHIPO_0001141 obsolete host effector triggered immunity signaling induced hypersensitive response activated by pathogen A cell signaling pathway phenotype where the host effector-triggered immunity signaling pathway is induced by a pathogen to activate a plant hypersensitive response and induce necrosis. http://purl.obolibrary.org/obo/GO_0044237 obsolete cellular metabolic process OBSOLETE. The chemical reactions and pathways by which individual cells transform chemical substances. http://purl.obolibrary.org/obo/GO_0070265 obsolete necrotic cell death OBSOLETE. A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues. http://purl.obolibrary.org/obo/PHIPO_0000025 obsolete normal mating phenotype prior to penetration http://purl.obolibrary.org/obo/PHIPO_0000029 obsolete abnormal mating phenotype prior to penetration http://purl.obolibrary.org/obo/BFO_0000001 entity http://purl.obolibrary.org/obo/NCBITaxon_1 root http://purl.obolibrary.org/obo/SO_0001260 sequence_collection http://purl.obolibrary.org/obo/PHIPO_0000041 obsolete normal motility phenotype http://purl.obolibrary.org/obo/PHIPO_0000042 obsolete abnormal motility phenotype http://purl.obolibrary.org/obo/PHIPO_0000058 obsolete normal timing in production of sexual spores http://purl.obolibrary.org/obo/PHIPO_0000060 obsolete normal timing in production of asexual spores http://purl.obolibrary.org/obo/PHIPO_0000066 obsolete abnormal timing of asexual spore production http://purl.obolibrary.org/obo/PHIPO_0000074 obsolete abnormal timing of sexual spore production http://purl.obolibrary.org/obo/PHIPO_0000083 obsolete abnormal asexual spore motility http://purl.obolibrary.org/obo/PHIPO_0000084 obsolete increased asexual spore motility http://purl.obolibrary.org/obo/PHIPO_0000085 obsolete decreased asexual spore motility http://purl.obolibrary.org/obo/PHIPO_0000086 obsolete normal asexual spore motility http://purl.obolibrary.org/obo/PHIPO_0000087 obsolete normal binary fission http://purl.obolibrary.org/obo/PHIPO_0000088 obsolete normal budding http://purl.obolibrary.org/obo/PHIPO_0000089 obsolete normal fragmentation http://purl.obolibrary.org/obo/PHIPO_0000090 obsolete normal parthenogenesis http://purl.obolibrary.org/obo/PHIPO_0000091 obsolete abnormal budding http://purl.obolibrary.org/obo/PHIPO_0000092 obsolete abnormal binary fission http://purl.obolibrary.org/obo/PHIPO_0000093 obsolete abnormal parthenogenesis http://purl.obolibrary.org/obo/PHIPO_0000094 obsolete normal mitosis in asexual reproduction http://purl.obolibrary.org/obo/PHIPO_0000095 obsolete abnormal mitosis in asexual reproduction http://purl.obolibrary.org/obo/PHIPO_0000100 obsolete increased motility http://purl.obolibrary.org/obo/PHIPO_0000101 obsolete decreased motility http://purl.obolibrary.org/obo/PHIPO_0000102 obsolete loss of motility http://purl.obolibrary.org/obo/PHIPO_0000103 obsolete gain of motility http://purl.obolibrary.org/obo/PHIPO_0000112 obsolete non-functional penetration structure present http://purl.obolibrary.org/obo/PHIPO_0000124 obsolete abnormal penetration structure present http://purl.obolibrary.org/obo/PHIPO_0000125 obsolete abnormal pathogen growth post penetration present http://purl.obolibrary.org/obo/PHIPO_0000157 obsolete motility phenotype http://purl.obolibrary.org/obo/PHIPO_0000165 obsolete abnormal host lesion formation with pathogen http://purl.obolibrary.org/obo/PHIPO_0000166 obsolete chlorosis phenotype http://purl.obolibrary.org/obo/PHIPO_0000169 obsolete chlorosis absent http://purl.obolibrary.org/obo/PHIPO_0000170 obsolete chlorosis present http://purl.obolibrary.org/obo/PHIPO_0000184 obsolete pathogen adhesion to host phenotype http://purl.obolibrary.org/obo/PHIPO_0000195 obsolete normal host lesion formation with pathogen http://purl.obolibrary.org/obo/PHIPO_0000209 obsolete increased stature http://purl.obolibrary.org/obo/PHIPO_0000211 obsolete decreased stature http://purl.obolibrary.org/obo/PHIPO_0000216 obsolete pathogen host interaction disease symptom phenotype http://purl.obolibrary.org/obo/PHIPO_0000224 obsolete altered colour of host lesion with pathogen http://purl.obolibrary.org/obo/PHIPO_0000277 obsolete abnormal filamentous growth http://purl.obolibrary.org/obo/PHIPO_0000279 obsolete systemic phenotype http://purl.obolibrary.org/obo/PHIPO_0000281 obsolete stature phenotype http://purl.obolibrary.org/obo/PHIPO_0000282 obsolete abnormal stature http://purl.obolibrary.org/obo/PHIPO_0000283 obsolete normal stature http://purl.obolibrary.org/obo/PHIPO_0000289 obsolete altered colour http://purl.obolibrary.org/obo/PHIPO_0000290 obsolete colour present http://purl.obolibrary.org/obo/PHIPO_0000291 obsolete colour absent http://purl.obolibrary.org/obo/PHIPO_0000293 obsolete abnormal organism morphology phenotype http://purl.obolibrary.org/obo/PHIPO_0000294 obsolete normal organism morphology phenotype http://purl.obolibrary.org/obo/PHIPO_0000296 obsolete normal dissemination of pathogen asexual product http://purl.obolibrary.org/obo/PHIPO_0000297 obsolete normal dissemination of pathogen sexual product http://purl.obolibrary.org/obo/PHIPO_0000298 obsolete abnormal dissemination of pathogen asexual product http://purl.obolibrary.org/obo/PHIPO_0000299 obsolete abnormal dissemination of pathogen sexual product http://purl.obolibrary.org/obo/PHIPO_0000336 obsolete intracellular growth phenotype http://purl.obolibrary.org/obo/PHIPO_0000337 obsolete extracellular growth phenotype http://purl.obolibrary.org/obo/PHIPO_0000344 obsolete normal pathogen host interaction molecular function http://purl.obolibrary.org/obo/PHIPO_0000345 obsolete abnormal pathogen host interaction molecular function http://purl.obolibrary.org/obo/PHIPO_0000346 obsolete host necrotic lesion with pathogen phenotype http://purl.obolibrary.org/obo/PHIPO_0000399 obsolete abnormal phialide morphology http://purl.obolibrary.org/obo/PHIPO_0000401 obsolete normal phialide morphology http://purl.obolibrary.org/obo/PHIPO_0000408 obsolete morphology phenotype http://purl.obolibrary.org/obo/PHIPO_0000417 obsolete abnormal pathogen host interaction pathogen carbohydrate binding phenotype http://purl.obolibrary.org/obo/PHIPO_0000428 obsolete normal pathogen host interaction pathogen carbohydrate binding phenotype http://purl.obolibrary.org/obo/PHIPO_0000429 obsolete normal pathogen and host chitinases bind pathogen chitin and chitin fragments http://purl.obolibrary.org/obo/PHIPO_0000470 obsolete location of pathogen growth within host phenotype http://purl.obolibrary.org/obo/PHIPO_0000506 obsolete single species http://purl.obolibrary.org/obo/PHIPO_0000507 obsolete pathogen host interaction http://purl.obolibrary.org/obo/GO_0071676 negative regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071677 positive regulation of mononuclear cell migration http://purl.obolibrary.org/obo/GO_0071675 regulation of mononuclear cell migration Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0071696 ectodermal placode development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0071697 ectodermal placode morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. http://purl.obolibrary.org/obo/GO_0071764 nuclear outer membrane organization http://purl.obolibrary.org/obo/GO_0071763 nuclear membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. http://purl.obolibrary.org/obo/GO_0071868 cellular response to monoamine stimulus http://purl.obolibrary.org/obo/GO_1901699 cellular response to nitrogen compound Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan. http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine http://purl.obolibrary.org/obo/GO_0071867 response to monoamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/GO_0071870 cellular response to catecholamine stimulus http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine http://purl.obolibrary.org/obo/GO_0071869 response to catecholamine Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0071874 cellular response to norepinephrine stimulus http://purl.obolibrary.org/obo/GO_0071873 response to norepinephrine Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. http://purl.obolibrary.org/obo/GO_0071888 macrophage apoptotic process http://purl.obolibrary.org/obo/GO_0071887 leukocyte apoptotic process Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues. http://purl.obolibrary.org/obo/GO_0071953 elastic fiber http://purl.obolibrary.org/obo/GO_0099512 supramolecular fiber An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. http://purl.obolibrary.org/obo/GO_0071971 extracellular exosome assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Exosomes are defined by their size, which generally ranges from 30 nm to 100 nm. http://purl.obolibrary.org/obo/GO_0072091 regulation of stem cell proliferation http://purl.obolibrary.org/obo/GO_0042127 regulation of cell population proliferation Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. http://purl.obolibrary.org/obo/GO_0072201 negative regulation of mesenchymal cell proliferation http://purl.obolibrary.org/obo/GO_0008285 negative regulation of cell population proliferation Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. http://purl.obolibrary.org/obo/GO_0072360 vascular cord development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. http://purl.obolibrary.org/obo/GO_0072577 endothelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal. http://purl.obolibrary.org/obo/GO_0072592 oxygen metabolic process http://purl.obolibrary.org/obo/GO_0008152 metabolic process The chemical reactions and pathways involving diatomic oxygen (O2). http://purl.obolibrary.org/obo/GO_0072597 maintenance of protein location in chloroplast http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0072598 protein localization to chloroplast http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained at, a location in a chloroplast. http://purl.obolibrary.org/obo/GO_0072656 maintenance of protein location in mitochondrion http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0072665 protein localization to vacuole http://purl.obolibrary.org/obo/GO_0033365 protein localization to organelle A process in which a protein is transported to, or maintained at, a location in a vacuole. http://purl.obolibrary.org/obo/GO_0072667 maintenance of protein location in vacuole http://purl.obolibrary.org/obo/GO_0072595 maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere. http://purl.obolibrary.org/obo/GO_0072674 multinuclear osteoclast differentiation http://purl.obolibrary.org/obo/GO_0030316 osteoclast differentiation The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue. http://purl.obolibrary.org/obo/GO_0075009 germ tube formation http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0075010 regulation of germ tube formation http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0075015 formation of infection structure http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The formation of a symbiont structure that serves to infect its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0075053 penetration peg formation http://purl.obolibrary.org/obo/GO_0075015 formation of infection structure The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0075054 modulation of penetration peg formation http://purl.obolibrary.org/obo/GO_0052372 modulation by symbiont of entry into host Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction. http://purl.obolibrary.org/obo/GO_0090425 acinar cell differentiation http://purl.obolibrary.org/obo/GO_0002067 glandular epithelial cell differentiation The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini. http://purl.obolibrary.org/obo/GO_0097084 vascular associated smooth muscle cell development http://purl.obolibrary.org/obo/GO_0055001 muscle cell development The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels. http://purl.obolibrary.org/obo/GO_0097094 craniofacial suture morphogenesis http://purl.obolibrary.org/obo/GO_0009653 anatomical structure morphogenesis The process in which any suture between cranial and/or facial bones is generated and organized. http://purl.obolibrary.org/obo/GO_0097530 granulocyte migration http://purl.obolibrary.org/obo/GO_0097529 myeloid leukocyte migration The movement of a granulocyte within or between different tissues and organs of the body. http://purl.obolibrary.org/obo/GO_0097712 vesicle targeting, trans-Golgi to periciliary membrane compartment http://purl.obolibrary.org/obo/GO_0048199 vesicle targeting, to, from or within Golgi The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. http://purl.obolibrary.org/obo/GO_0097734 extracellular exosome biogenesis http://purl.obolibrary.org/obo/GO_0140112 extracellular vesicle biogenesis The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. http://purl.obolibrary.org/obo/GO_0099124 axonal dopamine secretion http://purl.obolibrary.org/obo/GO_0014046 dopamine secretion The regulated release of dopamine from an axon. http://purl.obolibrary.org/obo/GO_0099565 chemical synaptic transmission, postsynaptic http://purl.obolibrary.org/obo/GO_0050877 nervous system process The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol. http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding http://purl.obolibrary.org/obo/GO_0043393 regulation of protein binding Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/GO_1900121 negative regulation of receptor binding http://purl.obolibrary.org/obo/GO_1900120 regulation of receptor binding Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor. http://purl.obolibrary.org/obo/GO_1901343 negative regulation of vasculature development http://purl.obolibrary.org/obo/GO_1901342 regulation of vasculature development Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. http://purl.obolibrary.org/obo/GO_1901653 cellular response to peptide http://purl.obolibrary.org/obo/GO_1901652 response to peptide Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. http://purl.obolibrary.org/obo/GO_1901963 regulation of cell proliferation involved in outflow tract morphogenesis http://purl.obolibrary.org/obo/GO_2000136 regulation of cell proliferation involved in heart morphogenesis Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. http://purl.obolibrary.org/obo/GO_1902019 regulation of cilium-dependent cell motility http://purl.obolibrary.org/obo/GO_2000145 regulation of cell motility Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1904748 regulation of apoptotic process involved in development Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902338 negative regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902339 positive regulation of apoptotic process involved in morphogenesis http://purl.obolibrary.org/obo/GO_1902337 regulation of apoptotic process involved in morphogenesis Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis. http://purl.obolibrary.org/obo/GO_1902414 protein localization to cell junction http://purl.obolibrary.org/obo/GO_0008104 intracellular protein localization A process in which a protein is transported to, or maintained in, a location within a cell junction. http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1902867 negative regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1902868 positive regulation of retina development in camera-type eye http://purl.obolibrary.org/obo/GO_1902866 regulation of retina development in camera-type eye Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. http://purl.obolibrary.org/obo/GO_1903296 positive regulation of glutamate secretion, neurotransmission http://purl.obolibrary.org/obo/GO_0051968 positive regulation of synaptic transmission, glutamatergic Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter. http://purl.obolibrary.org/obo/GO_1903561 extracellular vesicle http://purl.obolibrary.org/obo/GO_0031982 vesicle Any vesicle that is part of the extracellular region. http://purl.obolibrary.org/obo/GO_1903867 extraembryonic membrane development http://purl.obolibrary.org/obo/GO_0048856 anatomical structure development The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. http://purl.obolibrary.org/obo/GO_1904019 epithelial cell apoptotic process http://purl.obolibrary.org/obo/GO_0006915 apoptotic process Any apoptotic process in an epithelial cell. http://purl.obolibrary.org/obo/GO_1904359 regulation of spore germination http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of spore germination. http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination http://purl.obolibrary.org/obo/GO_0051128 regulation of cellular component organization Any process that modulates the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905154 negative regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905155 positive regulation of membrane invagination http://purl.obolibrary.org/obo/GO_1905153 regulation of membrane invagination Any process that activates or increases the frequency, rate or extent of membrane invagination. http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_2000026 regulation of multicellular organismal development Any process that modulates the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905278 positive regulation of epithelial tube formation http://purl.obolibrary.org/obo/GO_1905276 regulation of epithelial tube formation Any process that activates or increases the frequency, rate or extent of epithelial tube formation. http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_2000736 regulation of stem cell differentiation Any process that modulates the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905293 negative regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905294 positive regulation of neural crest cell differentiation http://purl.obolibrary.org/obo/GO_1905292 regulation of neural crest cell differentiation Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. http://purl.obolibrary.org/obo/GO_1905349 ciliary transition zone assembly http://purl.obolibrary.org/obo/GO_0022607 cellular component assembly The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. http://purl.obolibrary.org/obo/GO_1905516 positive regulation of fertilization http://purl.obolibrary.org/obo/GO_2000243 positive regulation of reproductive process Any process that activates or increases the frequency, rate or extent of fertilization. http://purl.obolibrary.org/obo/GO_1905634 regulation of protein localization to chromatin http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to chromatin. http://purl.obolibrary.org/obo/GO_1905809 negative regulation of synapse organization http://purl.obolibrary.org/obo/GO_0051129 negative regulation of cellular component organization Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization. http://purl.obolibrary.org/obo/GO_2000543 positive regulation of gastrulation http://purl.obolibrary.org/obo/GO_0010470 regulation of gastrulation Any process that activates or increases the frequency, rate or extent of gastrulation. http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_0051153 regulation of striated muscle cell differentiation Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000726 negative regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000727 positive regulation of cardiac muscle cell differentiation http://purl.obolibrary.org/obo/GO_2000725 regulation of cardiac muscle cell differentiation Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. http://purl.obolibrary.org/obo/GO_2000794 regulation of epithelial cell proliferation involved in lung morphogenesis http://purl.obolibrary.org/obo/GO_0050678 regulation of epithelial cell proliferation Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_0042981 regulation of apoptotic process Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/GO_2001054 negative regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/GO_2001055 positive regulation of mesenchymal cell apoptotic process http://purl.obolibrary.org/obo/GO_2001053 regulation of mesenchymal cell apoptotic process Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process. http://purl.obolibrary.org/obo/PR_000011178 nuclear factor NF-kappa-B p100 subunit http://purl.obolibrary.org/obo/PR_000001753 transcription factor NF-kappa-B subunit A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB2 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000011241 homeobox protein Nkx-2.1 http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human NKX2-1 gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013246 prolactin http://purl.obolibrary.org/obo/PR_000029968 somatotropin hormone family member A somatotropin hormone family member that is a translation product of the human PRL gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013433 parathyroid hormone-related protein http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human PTHLH gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000013502 parvalbumin alpha http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human PVALB gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_000014419 protein S100-B http://purl.obolibrary.org/obo/CHEBI_36080 protein A protein that is a translation product of the human S100B gene or a 1:1 ortholog thereof. http://purl.obolibrary.org/obo/PR_Q62226 sonic hedgehog protein (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A sonic hedgehog protein that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O35305 tumor necrosis factor receptor superfamily member 11A (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A tumor necrosis factor receptor superfamily member 11A that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_O54990 prominin-1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A prominin-1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P10810 monocyte differentiation antigen CD14 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD14 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P13379 T-cell surface glycoprotein CD5 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A T-cell surface glycoprotein CD5 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P13595 neural cell adhesion molecule 1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neural cell adhesion molecule 1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P15655 fibroblast growth factor 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A fibroblast growth factor 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P50114 protein S100-B (mouse) http://purl.obolibrary.org/obo/PR_000014419 protein S100-B A protein S100-B that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P50220 homeobox protein Nkx-2.1 (mouse) http://purl.obolibrary.org/obo/PR_000011241 homeobox protein Nkx-2.1 A homeobox protein Nkx-2.1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P50283 T-cell antigen CD7 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CD7 molecule that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P51683 C-C chemokine receptor type 2 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A C-C chemokine receptor type 2 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_P53566 CCAAT/enhancer-binding protein alpha (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A CCAAT/enhancer-binding protein alpha that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61391 neprilysin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A neprilysin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61549 adhesion G protein-coupled receptor E1 (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein An adhesion G protein-coupled receptor E1 that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q61616 D(1A) dopamine receptor (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A D(1A) dopamine receptor that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/PR_Q8CG65 SCO-spondin (mouse) http://purl.obolibrary.org/obo/PR_000029032 Mus musculus protein A SCO-spondin that is encoded in the genome of mouse. http://purl.obolibrary.org/obo/CL_0001065 innate lymphoid cell http://purl.obolibrary.org/obo/CL_0000542 lymphocyte A lymphocyte that lacks characteristic T cell, B cell, myeloid cell, and dendritic cell markers, that functions as part of the innate immune response to produce cytokines and other effector responses. http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalytic activity that acts to modify a protein. http://purl.obolibrary.org/obo/GO_0140097 catalytic activity, acting on DNA http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify DNA. http://purl.obolibrary.org/obo/GO_0140098 catalytic activity, acting on RNA http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid Catalytic activity that acts to modify RNA. http://purl.obolibrary.org/obo/GO_0140101 catalytic activity, acting on a tRNA http://purl.obolibrary.org/obo/GO_0140098 catalytic activity, acting on RNA Catalytic activity that acts to modify a tRNA. http://purl.obolibrary.org/obo/GO_0140103 catalytic activity, acting on a glycoprotein http://purl.obolibrary.org/obo/GO_0140096 catalytic activity, acting on a protein Catalysis of a biochemical reaction in which one of the substrates is a glycoprotein. http://purl.obolibrary.org/obo/GO_0140375 immune receptor activity http://purl.obolibrary.org/obo/GO_0038023 signaling receptor activity Receiving a signal and transmitting it in a cell to initiate an immune response. http://purl.obolibrary.org/obo/GO_0062237 protein localization to postsynapse http://purl.obolibrary.org/obo/GO_0035418 protein localization to synapse Any process in which a protein is transported to, and/or maintained at the postsynapse, the part of a synapse that is part of the post-synaptic cell. http://purl.obolibrary.org/obo/CHEBI_167164 mineral nutrient http://purl.obolibrary.org/obo/CHEBI_46662 mineral A mineral that is an inorganic nutrient which must be ingested and absorbed in adequate amounts to satisfy a wide range of essential metabolic and/or structural functions in the human body. http://purl.obolibrary.org/obo/CHEBI_167183 piscicide http://purl.obolibrary.org/obo/CHEBI_25944 pesticide A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water. http://purl.obolibrary.org/obo/GO_0140640 catalytic activity, acting on a nucleic acid http://purl.obolibrary.org/obo/GO_0003824 catalytic activity Catalytic activity that acts to modify a nucleic acid. http://purl.obolibrary.org/obo/GO_0140657 ATP-dependent activity http://purl.obolibrary.org/obo/GO_0003674 gene product or complex activity A molecular function characterized by the coupling of ATP hydrolysis to other steps of a reaction mechanism to make the reaction energetically favorable, for example to catalyze a reaction or drive transport against a concentration gradient. http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx A transcriptomically distinct type of mesothelial fibroblast that is derived from the neural crest, is localized on blood vessels, and is a key component of the pia and arachnoid membranes surrounding the brain. The standard transcriptomic reference data for this cell type can be found on the CellxGene census under the collection: 'Transcriptomic cytoarchitecture reveals principles of human neocortex organization', dataset: 'Supercluster: Non-neuronal cells', Author Categories: 'CrossArea_subclass', clusters VLMC. http://purl.obolibrary.org/obo/GO_0140820 cytosol to Golgi apparatus transport http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of substances from the cytosol into the Golgi apparatus of a cell. http://purl.obolibrary.org/obo/CHEBI_190509 imipenem zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion Zwitterionic form of imipenem having an anionic carboxy group and a protonated methaneimidamido group; major species at pH 7.3. http://purl.obolibrary.org/obo/CL_4023026 direct pathway medium spiny neuron http://purl.obolibrary.org/obo/CL_1001474 medium spiny neuron A GABAergic medium spiny neuron located in the striatum that gives rise to the direct basal ganglia pathway. It projects directly to the GPi and SNr, where it inhibits tonically active GABAergic output neurons to disinhibit thalamic and brainstem motor targets (Gerfen. 2023). In mice and humans, this cell selectively expresses the D1 dopamine receptor (DRD1), which couples to stimulatory G-proteins (Gs/Gαolf) to increase cAMP and activate PKA-dependent signaling cascades (Gerfen et al., 1990; Kebabian & Calne, 1979). Functionally, activation of this cell promotes selected motor actions by disinhibiting thalamic and midbrain motor centers (Mink, 1996; Cui et al., 2013). http://purl.obolibrary.org/obo/PHIPO_0001271 presence of pathogen sexual spores within host http://purl.obolibrary.org/obo/PHIPO_0000443 normal pathogen sexual reproduction within host A pathogen reproductive phenotype within host in which the frequency of occurrence of sexual spores is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001272 stunted growth http://purl.obolibrary.org/obo/PHIPO_0000402 individual organism phenotype A single species growth phenotype where there is a decrease in size of an entire multicellular organism. http://purl.obolibrary.org/obo/PHIPO_0001273 abnormal host morphology during phagocytosis of pathogen http://purl.obolibrary.org/obo/PHIPO_0001006 abnormal host morphology during pathogen invasion A pathogen host interaction phenotype where the morphology of the host cell is irregular due to the phagocytosis (engulfment and ingestion) of the pathogen (GO:0006911). http://purl.obolibrary.org/obo/PHIPO_0001274 host immune system phagocytosis of pathogen present http://purl.obolibrary.org/obo/PHIPO_0001167 pathogen modulation of host immune system process phenotype A pathogen host interaction phenotype where the host immune system activates the phagocytosis of a pathogen (GO:0006911). http://purl.obolibrary.org/obo/PHIPO_0001275 presence of viable pathogen sexual spores within host http://purl.obolibrary.org/obo/PHIPO_0001271 presence of pathogen sexual spores within host A pathogen reproductive phenotype within host in which the viability of sexual spores is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001276 increased number of host galls during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0001268 presence of host gall during pathogen invasion A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in an increased number of plant galls (BTO:0005833 plant gall). http://purl.obolibrary.org/obo/PHIPO_0001277 presence of pathogen induced host DNA synthesis http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype in which host DNA synthesis occurs during pathogen infection (GO:0090592 DNA synthesis involved in DNA replication). http://purl.obolibrary.org/obo/PHIPO_0001278 decreased pathogen induced host DNA synthesis http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype in which the host DNA synthesis during pathogen infection occurs to a lesser extent than normal (GO:0090592 DNA synthesis involved in DNA replication). http://purl.obolibrary.org/obo/PHIPO_0001279 abolished peptidase activity http://purl.obolibrary.org/obo/PHIPO_0000435 abolished catalytic activity A single species molecular function phenotype in which a peptidase activity is absent. http://purl.obolibrary.org/obo/PHIPO_0001280 increased pathogen induced host DNA synthesis http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype in which the host DNA synthesis during pathogen infection occurs to a greater extent than normal (GO:0090592 DNA synthesis involved in DNA replication). http://purl.obolibrary.org/obo/PHIPO_0001281 presence of host protein phosphorylation with pathogen http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, occurs during pathogen infection (GO:0006468 protein phosphorylation). http://purl.obolibrary.org/obo/PHIPO_0001282 absence of host protein phosphorylation with pathogen http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, does not occur during pathogen infection (GO:0006468 protein phosphorylation). http://purl.obolibrary.org/obo/PHIPO_0001283 increased host protein phosphorylation with pathogen http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, during pathogen infection occurs to a greater extent than normal (GO:0006468 protein phosphorylation). http://purl.obolibrary.org/obo/PHIPO_0001284 decreased host protein phosphorylation with pathogen http://purl.obolibrary.org/obo/PHIPO_0001247 pathogen modulation of host metabolic process phenotype A pathogen host interaction phenotype in which the phosphorylation of one or more specific host proteins, or of specific host protein sites, during pathogen infection occurs to a lesser extent than normal (GO:0006468 protein phosphorylation). http://purl.obolibrary.org/obo/PHIPO_0001285 increased level of host defense-related RNA involved in a pathogen interaction http://purl.obolibrary.org/obo/PHIPO_0001104 increased level of host defense-induced RNA A pathogen host interaction phenotype, in which the level of host defense-related RNA usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001286 presence of pathogen protein host DNA interaction http://purl.obolibrary.org/obo/PHIPO_0000164 pathogen host interaction binding phenotype A molecular function phenotype in which the binding of one pathogen protein to host DNA is present. http://purl.obolibrary.org/obo/UBERON_8600004 visceral muscle tissue http://purl.obolibrary.org/obo/UBERON_0002385 muscle tissue A muscle tissue that is associated with soft internal organs (viscera). http://purl.obolibrary.org/obo/CL_4033018 lung megakaryocyte http://purl.obolibrary.org/obo/CL_0002320 connective tissue cell A megakaryocyte that is resident in the lung connective tissue. http://purl.obolibrary.org/obo/CL_4033054 perivascular cell http://purl.obolibrary.org/obo/CL_0000000 cell A cell that is adjacent to a vessel. A perivascular cell plays a crucial role in maintaining vascular function and tissue homeostasis. This cell type regulates vessel integrity and flow dynamics. http://purl.obolibrary.org/obo/CL_4040004 mesenchymal stem cell of orbital adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an orbital region. http://purl.obolibrary.org/obo/CHEBI_228364 NMR chemical shift reference compound http://purl.obolibrary.org/obo/CHEBI_747204 reference compound Any compound that produces a peak used as reference frequency in the δ chemical shift scale. http://purl.obolibrary.org/obo/GO_0170034 L-amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids. http://purl.obolibrary.org/obo/GO_0170035 L-amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of an L-amino acid. http://purl.obolibrary.org/obo/GO_0170038 proteinogenic amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/GO_0170040 proteinogenic amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170039 proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. http://purl.obolibrary.org/obo/GO_0170043 non-proteinogenic amino acid biosynthetic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids. http://purl.obolibrary.org/obo/GO_0170044 non-proteinogenic amino acid catabolic process http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids. http://purl.obolibrary.org/obo/GO_0140001 morula formation http://purl.obolibrary.org/obo/GO_0048646 anatomical structure formation involved in morphogenesis The initial formation of a spherical embryonic mass of blastomeres formed before the blastula and resulting from cleavage of the fertilized ovum. http://purl.obolibrary.org/obo/CL_4300102 STR D2 Gaba indirect pathway medium spiny neuron (Mmus) http://purl.obolibrary.org/obo/CL_4023029 indirect pathway medium spiny neuron A indirect pathway medium spiny neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Adora2a (Mmus), Phactr1 (Mmus), Pcp4l1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:062 STR D2 Gaba. http://purl.obolibrary.org/obo/CARO_0000000 anatomical entity http://purl.obolibrary.org/obo/BFO_0000040 material entity A part of a multicellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex. Or, a substance produced by a multicellular organism with granularity above the level of a protein complex. http://purl.obolibrary.org/obo/IDO_0000450 pathogenic disposition http://purl.obolibrary.org/obo/BFO_0000016 disposition A disposition to initiate processes that result in a disorder. http://purl.obolibrary.org/obo/IDO_0000528 pathogen http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity with a pathogenic disposition. http://purl.obolibrary.org/obo/IDO_0000626 appearance of disorder http://purl.obolibrary.org/obo/GO_0008150 biological process A process by which a disorder comes into existence. http://purl.obolibrary.org/obo/OGMS_0000045 disorder http://purl.obolibrary.org/obo/BFO_0000040 material entity A material entity which is clinically abnormal and part of an extended organism. Disorders are the physical basis of disease. http://purl.obolibrary.org/obo/GO_1905955 negative regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_1905956 positive regulation of endothelial tube morphogenesis http://purl.obolibrary.org/obo/GO_1901509 regulation of endothelial tube morphogenesis Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. http://purl.obolibrary.org/obo/GO_0090741 pigment granule membrane http://purl.obolibrary.org/obo/GO_0030659 cytoplasmic vesicle membrane Any membrane that is part of a pigment granule. http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_1902513 regulation of organelle transport along microtubule Any process that modulates the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0061881 positive regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion Any process that activates or increasesthe frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0061882 negative regulation of anterograde axonal transport of mitochondrion http://purl.obolibrary.org/obo/GO_0061880 regulation of anterograde axonal transport of mitochondrion Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse. http://purl.obolibrary.org/obo/GO_0061888 regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0050865 regulation of cell activation Any process that modulates the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/GO_0061889 negative regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response Any process that decreases the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/GO_0061890 positive regulation of astrocyte activation http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response Any process that increases the frequency, rate or extent of astrocyte activation. http://purl.obolibrary.org/obo/GO_0106110 vomitoxin biosynthetic process http://purl.obolibrary.org/obo/GO_0043386 mycotoxin biosynthetic process The chemical reactions and pathways resulting in the formation of type B trichothecene vomitoxin, also known as deoxynivalenol, a poisonous substance produced by some species of fungi and predominantly occurs in grains such as wheat, barley and oats. http://purl.obolibrary.org/obo/PHIPO_0001219 normal growth on voriconazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to voriconazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001220 physical quality phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A phenotype that affects any physical object quality, such as morphology, number, location, etc., of an individual, tissue, cell, or cellular component. http://purl.obolibrary.org/obo/PHIPO_0001221 abnormal anatomical structure physical quality phenotype http://purl.obolibrary.org/obo/PHIPO_0001373 anatomical structure physical quality phenotype A physical anatomical structure phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part, cell, or tissue, or individual is abnormal in the vegetative growth phase of the life cycle. http://purl.obolibrary.org/obo/PHIPO_0001222 cell viability phenotype http://purl.obolibrary.org/obo/PHIPO_0000034 cell phenotype A single species cell phenotype that consists of the cell's disposition to survive and develop normally. http://purl.obolibrary.org/obo/PHIPO_0001223 normal organism morphology http://purl.obolibrary.org/obo/PHIPO_0001220 physical quality phenotype A single species phenotype where the morphology of an organism is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001224 increased chitin hydrolysis present http://purl.obolibrary.org/obo/PHIPO_0001225 chitin hydrolysis present A single species metabolic cellular process phenotype, in which the occurrence of a pathogen effector preventing the hydrolysis of chitin by chitinases is decreased (chitin hydrolysis is increased). http://purl.obolibrary.org/obo/PHIPO_0001225 chitin hydrolysis present http://purl.obolibrary.org/obo/PHIPO_0001147 cellular metabolic process phenotype A single species metabolic cellular process phenotype, in which a pathogen effector does not prevent the hydrolysis of chitin by chitinases. http://purl.obolibrary.org/obo/UBERON_8440004 laminar subdivision of the cortex http://purl.obolibrary.org/obo/UBERON_0011215 central nervous system cell part cluster One or a subset of adjacent layers of the neocortex. http://purl.obolibrary.org/obo/CL_4028001 pulmonary capillary endothelial cell http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell Any capillary endothelial cell that is part of a lung. http://purl.obolibrary.org/obo/PHIPO_0001250 abnormal host structure induced by pathogen http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype where the development of a host structure is abnormal during pathogen infection. http://purl.obolibrary.org/obo/PHIPO_0001251 host defense-induced protein present http://purl.obolibrary.org/obo/PHIPO_0001262 host defense-induced protein level phenotype A pathogen host interaction phenotype, in which the host protein usually present during infection is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001252 decreased pathogen tissue to tissue migration within host http://purl.obolibrary.org/obo/PHIPO_0001159 pathogen tissue to tissue migration within host phenotype A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is decreased. http://purl.obolibrary.org/obo/PHIPO_0001253 host immune system inflammatory response activated by pathogen present http://purl.obolibrary.org/obo/PHIPO_0001167 pathogen modulation of host immune system process phenotype A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection is present. (GO:0006954 inflammatory response). http://purl.obolibrary.org/obo/PHIPO_0001254 decreased host immune inflammatory response with pathogen http://purl.obolibrary.org/obo/PHIPO_0001253 host immune system inflammatory response activated by pathogen present A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection occurs to a lesser extent than normal. (GO:0006954 inflammatory response). http://purl.obolibrary.org/obo/PHIPO_0001255 increased host immune inflammatory response with pathogen http://purl.obolibrary.org/obo/PHIPO_0001253 host immune system inflammatory response activated by pathogen present A pathogen host interaction phenotype where the host immune system inflammatory response during pathogen infection occurs to a greater extent than normal. (GO:0006954 inflammatory response). http://purl.obolibrary.org/obo/PHIPO_0001256 host defense-related protein involved in a pathogen interaction present http://purl.obolibrary.org/obo/PHIPO_0001251 host defense-induced protein present A pathogen host interaction phenotype, in which the host defense-related protein usually present during infection is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001257 decreased level of host defense-induced protein http://purl.obolibrary.org/obo/PHIPO_0001262 host defense-induced protein level phenotype A pathogen host interaction phenotype, in which the level of host protein usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001258 decreased expression of a host defense-related protein involved in a pathogen interaction http://purl.obolibrary.org/obo/PHIPO_0001257 decreased level of host defense-induced protein A pathogen host interaction phenotype, in which the level of host defense-related protein usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001259 host cell viability with pathogen phenotype http://purl.obolibrary.org/obo/PHIPO_0000510 pathogen host interaction cell phenotype A pathogen host interaction cell level phenotype which affects the viability of a host cell in the presence of a pathogen. http://purl.obolibrary.org/obo/PHIPO_0001260 host cell viable with pathogen http://purl.obolibrary.org/obo/PHIPO_0001259 host cell viability with pathogen phenotype A host cell viability phenotype where the host cell survives in the presence of the pathogen. http://purl.obolibrary.org/obo/PHIPO_0001261 host cell inviable with pathogen http://purl.obolibrary.org/obo/PHIPO_0001259 host cell viability with pathogen phenotype A host cell viability phenotype where the host cell death is accelerated by the pathogen. http://purl.obolibrary.org/obo/PHIPO_0001262 host defense-induced protein level phenotype http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, which affects the level of a host produced protein during infection. http://purl.obolibrary.org/obo/PHIPO_0001263 host defense-induced RNA level phenotype http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, which affects the level of a host produced RNA during infection. http://purl.obolibrary.org/obo/PHIPO_0001264 host physiological process affected by pathogen phenotype http://purl.obolibrary.org/obo/PHIPO_0001173 pathogen modulation of host process phenotype A pathogen host interaction phenotype, in which a pathogen effects a change in the physiological processes of its host organism. http://purl.obolibrary.org/obo/PHIPO_0001265 host hemorrhage with pathogen present http://purl.obolibrary.org/obo/PHIPO_0001264 host physiological process affected by pathogen phenotype A pathogen host interaction phenotype in which host bleeding occurs during pathogen infection (MP:0001914 hemorrhage). http://purl.obolibrary.org/obo/PHIPO_0001266 increased host hemorrhage with pathogen http://purl.obolibrary.org/obo/PHIPO_0001265 host hemorrhage with pathogen present A pathogen host interaction phenotype in which the host bleeding during pathogen infection occurs to a greater extent than normal (MP:0001914 hemorrhage). http://purl.obolibrary.org/obo/PHIPO_0001267 level of pathogen produced RNA within host phenotype http://purl.obolibrary.org/obo/PHIPO_0001197 level of pathogen produced substance within host phenotype A pathogen host interaction phenotype, which affects the level of pathogen produced RNA during host infection. http://purl.obolibrary.org/obo/PHIPO_0001268 presence of host gall during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0001006 abnormal host morphology during pathogen invasion A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in the abnormal growth of the host tissue, forming a plant gall (BTO:0005833 plant gall). http://purl.obolibrary.org/obo/PHIPO_0001269 decreased number of host galls during pathogen invasion http://purl.obolibrary.org/obo/PHIPO_0001268 presence of host gall during pathogen invasion A pathogen host interaction phenotype where the presence of a pathogen (or symbiont) has resulted in a decreased number of plant galls (BTO:0005833 plant gall). http://purl.obolibrary.org/obo/PHIPO_0001270 sensitive to calcium ion starvation http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress A growth phenotype which describes the sensitivity of individuals or populations after exposure to calcium ion starvation. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. http://purl.obolibrary.org/obo/CL_4023072 brain vascular cell http://purl.obolibrary.org/obo/CL_0002319 neural cell A cell that is part of the brain vasculature. http://purl.obolibrary.org/obo/UBERON_8600018 neuroendocrine system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system A regulatory system of the body that integrates the nervous system and the endocrine system. This system is formed by specialized neuroendocrine cells located mainly in the nervous system and neuroendocrine glands. However, they can also be found as either single cells or small clusters of cells dispersed throughout the surface epithelium of different tissues. The neuroendocrine system functions through the release of neurotransmitters and neurohormones, enabling communication between the endocrine and nervous systems to govern vitally important processes that include growth, reproduction, metabolism and energy homeostasis, electrolyte and water balance, and responses to stress. http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron that has its soma located in the striatum and that has an enriched expression of the genes TAC3 and LHX6. http://purl.obolibrary.org/obo/CL_4042003 border associated macrophage http://purl.obolibrary.org/obo/CL_0000878 central nervous system macrophage A central nervous system macrophage that is part of a choroid plexus, a meninx and a perivascular space. A border associated macrophage interacts with various components of the CNS vasculature and meninges, it participates in immune surveillance and in the regulation of the blood brain barrier. http://purl.obolibrary.org/obo/PHIPO_0001449 sensitive to ammonium http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to ammonium. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/UBERON_0035118 material entity in digestive tract http://purl.obolibrary.org/obo/UBERON_0000061 anatomical structure Any material entity that is located in the digestive tract. This includes undigested food and liquid as well as unexcreted waste products. It also includes other entities such as ingested stones used to aid digestion. Any microbial cells or cell populations are also included. http://purl.obolibrary.org/obo/UBERON_0035814 pericardial fat http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat The sum of epicardial and paracardial fat deposits. http://purl.obolibrary.org/obo/UBERON_0035818 visceral fat http://purl.obolibrary.org/obo/UBERON_0001013 adipose tissue Any fat deposit surrounding a visceral organ. http://purl.obolibrary.org/obo/UBERON_0036146 cardiopharyngeal field http://purl.obolibrary.org/obo/UBERON_0007688 anlage An region of the mesoderm that includes anterior lateral mesoderm of the first heart field plus contiguous pharyngeal mesoderm that gives rise to second-heart-field-derived regions of the heart and branchiomeric muscles. http://purl.obolibrary.org/obo/UBERON_0034947 gas in respiratory system http://purl.obolibrary.org/obo/UBERON_0034873 bodily gas Any portion of gas located in a part of the respiratory system. http://purl.obolibrary.org/obo/UBERON_0035159 entire surface of organism http://purl.obolibrary.org/obo/UBERON_0006984 anatomical surface Anatomical surface, which is the external surface of the whole body. Examples: There is only one body surface. http://purl.obolibrary.org/obo/GO_0110011 regulation of basement membrane organization http://purl.obolibrary.org/obo/GO_1903053 regulation of extracellular matrix organization Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. http://purl.obolibrary.org/obo/GO_0120031 plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0030031 cell projection assembly Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization http://purl.obolibrary.org/obo/GO_0031344 regulation of cell projection organization Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. http://purl.obolibrary.org/obo/CHEBI_139592 tertiary alpha-hydroxy ketone http://purl.obolibrary.org/obo/CHEBI_139588 alpha-hydroxy ketone An α-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups. http://purl.obolibrary.org/obo/GO_0150076 neuroinflammatory response http://purl.obolibrary.org/obo/GO_0006954 inflammatory response The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents. http://purl.obolibrary.org/obo/GO_0150078 positive regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050729 positive regulation of inflammatory response Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/GO_0150079 negative regulation of neuroinflammatory response http://purl.obolibrary.org/obo/GO_0050728 negative regulation of inflammatory response Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response. http://purl.obolibrary.org/obo/GO_0140354 lipid import into cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. http://purl.obolibrary.org/obo/PHIPO_0000948 mutualism absent http://purl.obolibrary.org/obo/PHIPO_0000039 normal mutualism A pathogen host interaction where the mutualism phenotype is normal (i.e. the same as wild-type), and the wild-type interaction does not exhibit mutualism. http://purl.obolibrary.org/obo/PHIPO_0000949 pathogen entry into host phenotype http://purl.obolibrary.org/obo/PHIPO_0000332 pathogen colonization of host phenotype A pathogen colonization of host phenotype which affects the penetration of the pathogen into the body, tissues, or cells of the host organism (GO:0044409). http://purl.obolibrary.org/obo/PHIPO_0000951 pathogen growth within host phenotype http://purl.obolibrary.org/obo/PHIPO_0000332 pathogen colonization of host phenotype A pathogen host phenotype which affects the vegetative growth or proliferation of the pathogen inside the host (e.g. after entry by penetration or infiltration). http://purl.obolibrary.org/obo/PHIPO_0000952 abolished pathogen growth within host http://purl.obolibrary.org/obo/PHIPO_0000363 absence of pathogen growth within host A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is abolished (it was present as is now absent). http://purl.obolibrary.org/obo/PHIPO_0000953 pathogen penetration structure present when near host http://purl.obolibrary.org/obo/PHIPO_0000352 normal formation of pathogen penetration structure prior to entry into host A pathogen growth with host phenotype in which the pathogen specialized host penetration structure is present. http://purl.obolibrary.org/obo/PHIPO_0000954 presence of pathogen growth within host http://purl.obolibrary.org/obo/PHIPO_0000951 pathogen growth within host phenotype A pathogen host phenotype in which the vegetative growth or proliferation of the pathogen inside the host is present. http://purl.obolibrary.org/obo/PHIPO_0000955 abolished formation of pathogen penetration structure when near host http://purl.obolibrary.org/obo/PHIPO_0000369 abnormal formation of pathogen penetration structure when near host A pathogen growth with host phenotype in which the ability of the pathogen to form a specialized penetration structure is abolished. http://purl.obolibrary.org/obo/PHIPO_0000956 normal asexual spore germination frequency http://purl.obolibrary.org/obo/PHIPO_0000509 population phenotype A population phenotype in which the frequency of occurrence of asexual spore germination is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0000959 normal cellular melanin accumulation http://purl.obolibrary.org/obo/PHIPO_0000286 normal cellular pigment accumulation A single species individual organism phenotype where the accumulation of melanin in a cell is normal. http://purl.obolibrary.org/obo/PHIPO_0000962 decreased filamentous growth on host surface http://purl.obolibrary.org/obo/PHIPO_0000349 presence of pathogen growth on host surface A pathogen colonization of host phenotype where the vegetative growth or proliferation of the pathogen on the host surface is decreased. http://purl.obolibrary.org/obo/PHIPO_0000964 loss of virulence http://purl.obolibrary.org/obo/PHIPO_0000015 reduced virulence A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is abolished on a specific host genotype. http://purl.obolibrary.org/obo/PHIPO_0000966 pathogen penetration structure present http://purl.obolibrary.org/obo/PHIPO_0000028 normal formation of pathogen penetration structure A single species pathogen growth phenotype in which the pathogen specialized host penetration structure is present when assessed for penetration ability on a given experimental substance/membrane. http://purl.obolibrary.org/obo/PHIPO_0000967 abolished pathogen penetration across the barrier http://purl.obolibrary.org/obo/PHIPO_0000030 pathogen penetration across the barrier absent A single species pathogen penetration phenotype in in which the ability of the pathogen to penetrate a given experimental substance/membrane is abolished. http://purl.obolibrary.org/obo/PHIPO_0000968 absent pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000027 normal pathogen growth after penetration of the barrier A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is absent. http://purl.obolibrary.org/obo/PHIPO_0000969 present pathogen growth after penetration of the barrier http://purl.obolibrary.org/obo/PHIPO_0000027 normal pathogen growth after penetration of the barrier A single species phenotype in which the pathogen's ability to contine to grow after penetration of a given experimental substance/membrane in an in vitro assay is present. http://purl.obolibrary.org/obo/CL_0008034 mural cell http://purl.obolibrary.org/obo/CL_4033054 perivascular cell Mural cells are pericytes and the vascular smooth muscle cells (vSMCs) of the microcirculation. http://purl.obolibrary.org/obo/CL_0008035 microcirculation associated smooth muscle cell http://purl.obolibrary.org/obo/CL_0008034 mural cell Any vascular associated smooth muscle cell that is part of some microcirculatory vessel. http://purl.obolibrary.org/obo/PHIPO_0001192 decreased level of host defense-induced reactive oxygen species http://purl.obolibrary.org/obo/PHIPO_0000924 host defense-induced oxidative burst level phenotype A pathogen host interaction phenotype, in which the level of host produced reactive oxygen species (ROS), often associated with an oxidative burst response during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001193 increased level of host defense-induced reactive oxygen species http://purl.obolibrary.org/obo/PHIPO_0000924 host defense-induced oxidative burst level phenotype A pathogen host interaction phenotype, in which the level of host produced reactive oxygen species (ROS), often associated with an oxidative burst response during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001194 inhibition of pathogen chorismate mutase by host absent http://purl.obolibrary.org/obo/PHIPO_0000347 pathogen host interaction molecular function phenotype A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen chorismate mutase is absent. http://purl.obolibrary.org/obo/PHIPO_0001195 inhibition of pathogen chorismate mutase by host present http://purl.obolibrary.org/obo/PHIPO_0000347 pathogen host interaction molecular function phenotype A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen chorismate mutase is present. http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype http://purl.obolibrary.org/obo/PHIPO_0000510 pathogen host interaction cell phenotype A pathogen host interaction phenotype, which affects the level of a host produced substance during infection. http://purl.obolibrary.org/obo/PHIPO_0001197 level of pathogen produced substance within host phenotype http://purl.obolibrary.org/obo/PHIPO_0000510 pathogen host interaction cell phenotype A pathogen host interaction phenotype, which affects the level of a pathogen produced substance during host infection. http://purl.obolibrary.org/obo/PATO_0070015 pyramidal family morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons which have a pyramidal shaped soma, a single axon, a large apical dendrite and multiple basal dendrites. http://purl.obolibrary.org/obo/CL_0017500 neutrophillic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits a characteristic staining and color, pale-pink, with Wright-Giemsa stain. http://purl.obolibrary.org/obo/CL_0017502 acidophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits a characteristic staining and color, red or pink, with Eosin stain. http://purl.obolibrary.org/obo/CL_0017503 basophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits molecular interaction for basic dyes under specific pH conditions. http://purl.obolibrary.org/obo/CL_0017504 polychromatophilic cytoplasm http://purl.obolibrary.org/obo/GO_0005737 cytoplasm Cytoplasm that exhibits affinity for both basic and acid stains under specific pH conditions. http://purl.obolibrary.org/obo/UBERON_0039856 right ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some inferior vena cava that drains the right pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/UBERON_0039857 left ovarian vein http://purl.obolibrary.org/obo/UBERON_0001145 ovarian vein Ovarian vein, each instance of which is a tributary of some left renal vein that drains the left pampiniform plexus of some broad ligament. http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei http://purl.obolibrary.org/obo/UBERON_0009663 telencephalic nucleus One of three components of the cerebrum that is a composite structure of the endbrain defined on the basis of origin from the ventricular ridge of the embryonic Encephalon. It consists of the extended striatum and the extended pallidum. http://purl.obolibrary.org/obo/CHEBI_194135 9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid http://purl.obolibrary.org/obo/CHEBI_53665 oxazinoquinoline An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively. http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Camk2a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1161 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307083 hypendemal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023181 hypendymal cell A hypendymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sspo (Mmus), Wfdc2 (Mmus). It is distinguished from other Astro-Epen cells by expression of Sspo, Wfdc2. These cells are located in the Midbrain, brain , in or close to the regions: third ventricle, posterior commissure, Subcommissural organ . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5263 Hypendymal NN_1. http://purl.obolibrary.org/obo/CL_4307036 Astro-NT NN_2 Fam227b astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Slc7a10 (Mmus), Cyp26b1 (Mmus), Igfbp2 (Mmus), Shroom3 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fam227b, Shroom3. These cells are located in the Midbrain, Medulla, Pons . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5216 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Homer3 (Mmus), Tfap2b (Mmus), Sorcs3 (Mmus), Cacna1e (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:311 CBX MLI Megf11 Gaba. http://purl.obolibrary.org/obo/CL_4072003 mature myelinating oligodendrocyte http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A post-mitotic oligodendrocyte derived from a myelin-forming oligodendrocyte (MFOL). A mature Myelinating Oligodendrocyte is a fully differentiated cell that is actively engaged in myelination. In addition to high expression of canonical myelin genes (e.g., Mbp, Plp1, Mog), a MOL can be distinguished by the expression of stage-enriched genes Grm3, Klk6, Ptgds, Anxa5, and Hopx in mice. These markers reflect the functional specialization of a mature oligodendrocyte, including roles in signalling, lipid metabolism, and myelin maintenance. http://purl.obolibrary.org/obo/CL_4306426 pinealocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000652 pinealocyte A pinealocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cngb3 (Mmus), Ush2a (Mmus). It is glutamatergic (inferred from expression of Ddc, Slc17a6, Slc17a7). These cells are located in the brain , in or close to the regions: third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:4606 Pineal Crx Glut_1. http://purl.obolibrary.org/obo/GO_0140115 export across plasma membrane http://purl.obolibrary.org/obo/GO_0055085 transmembrane transport The directed movement of some substance from inside of a cell, across the plasma membrane and into the extracellular region. http://purl.obolibrary.org/obo/CHEBI_140921 Hedgehog signaling pathway inhibitor http://purl.obolibrary.org/obo/CHEBI_76932 pathway inhibitor Any pathway inhibitor that inhibits the Hedgehog signalling pathway. http://purl.obolibrary.org/obo/CHEBI_140922 glioma-associated oncogene inhibitor http://purl.obolibrary.org/obo/CHEBI_35222 inhibitor An inhibitor of any of the glioma-associated oncogene (GLI) proteins. http://purl.obolibrary.org/obo/UBERON_0036285 wall of left ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of aorta. http://purl.obolibrary.org/obo/UBERON_0036286 wall of right ventricle http://purl.obolibrary.org/obo/UBERON_0004784 heart ventricle wall Wall of ventricle which is continuous with the wall of pulmonary trunk. http://purl.obolibrary.org/obo/UBERON_0036294 mucosa of lip http://purl.obolibrary.org/obo/UBERON_0003729 mouth mucosa A mucosa that is part of a lip region [Automatically generated definition]. http://purl.obolibrary.org/obo/GO_0150147 cell-cell junction disassembly http://purl.obolibrary.org/obo/GO_0045216 cell-cell junction organization The disaggregation of a cell-cell junction into its constituent components. http://purl.obolibrary.org/obo/CHEBI_145555 macropolylide http://purl.obolibrary.org/obo/CHEBI_25106 macrolide Macrolides (macrocyclic lactones) in which the macrocyclic ring contains more than one ester linkage. Macropolylides include macrodiolides, macrotriolides, macrotetrolides and macropentolides, each containing di-, tri-, tetra-, and penta- ester linkages, respectively, in one macrocyclic ring. Macrocyclic lactones containing nitrogen in their skeletons (azamacrolides and macrolide lactams) and also containing oxazole or thiazole in their skeletons are known in nature. http://purl.obolibrary.org/obo/CHEBI_145565 macrolide lactam http://purl.obolibrary.org/obo/CHEBI_25106 macrolide A macrolide in which the macrocyclic lactone ring includes an amide group. http://purl.obolibrary.org/obo/GO_0062197 cellular response to chemical stress http://purl.obolibrary.org/obo/GO_0070887 cellular response to chemical stimulus Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus indicating the organism is under stress. http://purl.obolibrary.org/obo/CHEBI_145790 mupirocin(1-) http://purl.obolibrary.org/obo/CHEBI_35757 monocarboxylic acid anion A monocarboxylic acid anion that is the conjugate base of mupirocin obtained by the deprotonation of the carboxy group; major microspecies at pH 7.3. http://purl.obolibrary.org/obo/GO_0120223 larynx morphogenesis http://purl.obolibrary.org/obo/GO_0009887 animal organ morphogenesis The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/GO_0120224 larynx development http://purl.obolibrary.org/obo/GO_0048513 animal organ development The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. http://purl.obolibrary.org/obo/CHEBI_146260 spectinomycin(1+) http://purl.obolibrary.org/obo/CHEBI_137419 secondary ammonium ion A secondary ammonium ion derived from spectinomycin by protonation of the secondary amino group located between the two alcoholic hydroxy groups. http://purl.obolibrary.org/obo/CHEBI_149553 anticoronaviral agent http://purl.obolibrary.org/obo/CHEBI_22587 antiviral agent Any antiviral agent which inhibits the activity of coronaviruses. http://purl.obolibrary.org/obo/CHEBI_149552 emetic http://purl.obolibrary.org/obo/CHEBI_23888 drug Any agent that induces nausea and vomiting. http://purl.obolibrary.org/obo/CL_0011019 mesothelial cell of epicardium http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesothelial cell that is part of the epicardium. http://purl.obolibrary.org/obo/CL_0011021 fibroblast of upper back skin http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back A fibroblast that is part of upper back skin. http://purl.obolibrary.org/obo/CL_0011022 fibroblast of skin of back http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast A fibroblast that is part of skin of back. http://purl.obolibrary.org/obo/CL_0019001 tracheobronchial serous cell http://purl.obolibrary.org/obo/CL_0000313 serous secreting cell Any serous secreting cell that is part of the tracheobronchial epithelium. http://purl.obolibrary.org/obo/CL_0019002 tracheobronchial chondrocyte http://purl.obolibrary.org/obo/CL_0000138 chondrocyte Any chondrocyte that is part of the tracheobronchial tree. http://purl.obolibrary.org/obo/PHIPO_0001154 decreased pathogen chitin fragment binding http://purl.obolibrary.org/obo/PHIPO_0000423 decreased carbohydrate binding A single species pathogen molecular function phenotype in which pathogen chitin fragment binding by a pathogen gene product is decreased. http://purl.obolibrary.org/obo/PHIPO_0001155 decreased level of pathogen reactive oxygen species production within host http://purl.obolibrary.org/obo/PHIPO_0001197 level of pathogen produced substance within host phenotype A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001156 increased level of pathogen reactive oxygen species production within host http://purl.obolibrary.org/obo/PHIPO_0001197 level of pathogen produced substance within host phenotype A pathogen host interaction phenotype, in which the level of pathogen produced reactive oxygen species (ROS) usually present during infection is higher than normal. http://purl.obolibrary.org/obo/PHIPO_0001159 pathogen tissue to tissue migration within host phenotype http://purl.obolibrary.org/obo/PHIPO_0000332 pathogen colonization of host phenotype A pathogen host interaction colonization phenotype which affects the directional tissue to tissue movement of the pathogen within the host organism (GO:0044001). http://purl.obolibrary.org/obo/PHIPO_0001160 abolished pathogen tissue to tissue migration within host http://purl.obolibrary.org/obo/PHIPO_0001159 pathogen tissue to tissue migration within host phenotype A pathogen host interaction colonization phenotype in which the ability of the pathogen to move directionally from tissue to tissue within the host organism is abolished (pathogen migration was present within the host and is now absent). http://purl.obolibrary.org/obo/PHIPO_0001161 host defense-induced phenolic compound absent http://purl.obolibrary.org/obo/PHIPO_0001196 host defense-induced substance level phenotype A pathogen host interaction phenotype, in which the host phenolic compounds usually present during infection are absent or at a level too low to detect. http://purl.obolibrary.org/obo/PHIPO_0001165 abnormal host seed development induced by pathogen http://purl.obolibrary.org/obo/PHIPO_0001250 abnormal host structure induced by pathogen A host reproductive phenotype with pathogen where the process of host seed development is abnormal (GO:0048316). http://purl.obolibrary.org/obo/PHIPO_0001166 absence of host seed development induced by pathogen http://purl.obolibrary.org/obo/PHIPO_0001165 abnormal host seed development induced by pathogen A host reproductive phenotype with pathogen where the process of host seed development is absent (GO:0048316). http://purl.obolibrary.org/obo/PHIPO_0001167 pathogen modulation of host immune system process phenotype http://purl.obolibrary.org/obo/PHIPO_0001173 pathogen modulation of host process phenotype A pathogen host interaction phenotype that affects a host immune system process during pathogen infection (GO:0002376). http://purl.obolibrary.org/obo/PHIPO_0001168 presence of pathogen inhibition of host immune response protease http://purl.obolibrary.org/obo/PHIPO_0001167 pathogen modulation of host immune system process phenotype A pathogen host interaction phenotype, in which the host immune response protease activity is inhibited by the pathogen. http://purl.obolibrary.org/obo/PHIPO_0001173 pathogen modulation of host process phenotype http://purl.obolibrary.org/obo/PHIPO_0000510 pathogen host interaction cell phenotype A pathogen host interaction phenotype, in which a pathogen effects a change in the structure or processes of its host organism (GO:0044003). http://purl.obolibrary.org/obo/PHIPO_0001174 decreased level of host defense-induced RNA http://purl.obolibrary.org/obo/PHIPO_0001263 host defense-induced RNA level phenotype A pathogen host interaction phenotype, in which the level of host RNA usually present during infection is lower than normal. http://purl.obolibrary.org/obo/PHIPO_0001175 normal pathogen protein localization within host http://purl.obolibrary.org/obo/PHIPO_0000236 pathogen host interaction localization phenotype A pathogen host interaction phenotype, in which the localization of a pathogen protein in a host cell is normal. http://purl.obolibrary.org/obo/PHIPO_0001176 effector-mediated immune suppression phenotype http://purl.obolibrary.org/obo/PHIPO_0000280 pathogen effector mediated modulation of host immune system process A phenotype dependent on an interaction between a pathogen effector and a host process in order for the pathogen to suppress the host immune system. An effector is an entity derived from a pathogenic or non-pathogenic species that either activates or suppresses host defenses or other host responses. http://purl.obolibrary.org/obo/PHIPO_0001179 infective ability phenotype http://purl.obolibrary.org/obo/PHIPO_0000001 pathogen host interaction phenotype A pathogen host interaction phenotype that affects the infective ability of a pathogen during attempted colonization of a host. http://purl.obolibrary.org/obo/PHIPO_0001180 absence of effector-independent host hypersensitive response http://purl.obolibrary.org/obo/PHIPO_0000446 host cell death phenotype A single species phenotype where the immune system process of host tissue hypersensitive response is absent in a pathogen effector-independant manner. (i.e. an alteration within the host does not activate the hypersensitive response in the absence of a pathogen). http://purl.obolibrary.org/obo/PHIPO_0001182 normal level of deoxynivalenol http://purl.obolibrary.org/obo/PHIPO_0001039 normal cellular toxin level A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001191 presence of melanin accumulation in pathogen asexual spore within host http://purl.obolibrary.org/obo/PHIPO_0001080 altered pathogen pigment accumulation within host A pathogen host interaction, in which the accumulation of melanin within a pathogen asexual spore, usually present during infection, is present. http://purl.obolibrary.org/obo/GO_0140899 plastid gene expression http://purl.obolibrary.org/obo/GO_0010467 gene expression The process in which a plastid gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0160038 somatic sensory system development http://purl.obolibrary.org/obo/GO_0048880 sensory system development The process whose specific outcome is the progression of a somatic sensory system over time from its formation to the mature structure. Somatic sensory system is the sensory system for the sense of touch and pain. http://purl.obolibrary.org/obo/GO_0160048 craniofacial suture closure http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process of fusing together the edges of a craniofacial suture. http://purl.obolibrary.org/obo/PHIPO_0001353 resistance to prothioconazole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to prothioconazole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001354 sensitive to prothioconazole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to prothioconazole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001355 normal growth on prothioconazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to prothioconazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001356 resistance to fluopyram http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fluopyram. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001357 sensitive to fluopyram http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fluopyram. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001358 normal growth on fluopyram http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to fluopyram (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001359 resistance to kresoxim-methyl http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to kresoxim-methyl. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001360 sensitive to kresoxim-methyl http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to kresoxim-methyl. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001361 normal growth on kresoxim-methyl http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to kresoxim-methyl (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001362 resistance to isopyrazam http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to isopyrazam. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001363 sensitive to isopyrazam http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to isopyrazam. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001364 normal growth on isopyrazam http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to isopyrazam (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001365 resistance to bixafen http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to bixafen. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001366 sensitive to bixafen http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to bixafen. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001367 normal growth on bixafen http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to bixafen (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001368 normal growth on carboxin http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to carboxin (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001369 increased rate of hyphae formation http://purl.obolibrary.org/obo/PHIPO_0001234 increased hyphal growth An individual organism growth phenotype in which the rate, or speed, of hyphae formation is increased. http://purl.obolibrary.org/obo/PHIPO_0001370 resistance to pyrimorph http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to pyrimorph. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001371 sensitive to pyrimorph http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrimorph. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001372 normal growth on pyrimorph http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrimorph (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001373 anatomical structure physical quality phenotype http://purl.obolibrary.org/obo/PHIPO_0001220 physical quality phenotype A phenotype that affects any anatomical structure physical quality, such as morphology, number, location, etc. http://purl.obolibrary.org/obo/PHIPO_0001374 increased number of resting structures http://purl.obolibrary.org/obo/PHIPO_0001221 abnormal anatomical structure physical quality phenotype A single species phenotype where the frequency of occurrence of resting structures is increased. http://purl.obolibrary.org/obo/PHIPO_0001375 decreased number of resting structures http://purl.obolibrary.org/obo/PHIPO_0001221 abnormal anatomical structure physical quality phenotype A single species phenotype where the frequency of occurrence of resting structures is decreased. http://purl.obolibrary.org/obo/PHIPO_0001376 normal anatomical structure physical quality phenotype http://purl.obolibrary.org/obo/PHIPO_0001373 anatomical structure physical quality phenotype A physical anatomical structure phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part, cell, or tissue, or individual is normal in the vegetative growth phase of the life cycle (i.e. indistinguishable from wild type.) http://purl.obolibrary.org/obo/PHIPO_0001377 normal number of resting structures http://purl.obolibrary.org/obo/PHIPO_0001376 normal anatomical structure physical quality phenotype A single species phenotype where the number of resting structures is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001378 resistance to tacrolimus http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to tacrolimus. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001379 sensitive to tacrolimus http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to tacrolimus. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001380 normal growth on tacrolimus http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to tacrolimus (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001381 sensitive to iron http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to iron. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001382 resistance to fenpiclonil http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to fenpiclonil. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001383 sensitive to fenpiclonil http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to fenpiclonil. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001384 normal growth on fenpiclonil http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to fenpiclonil (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001385 resistance to phenamacril http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to phenamacril. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001386 sensitive to phenamacril http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to phenamacril. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001387 normal growth on phenamacril http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to phenamacril (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/CHEBI_230471 EC 2.4.1.34 (1,3-beta-glucan synthase) inhibitor http://purl.obolibrary.org/obo/CHEBI_76789 EC 2.4.1.* (hexosyltransferase) inhibitor A EC 2.4.1.* (hexosyltransferase) inhibitor that inhibits the action of 1,3-β-glucan synthase (EC 2.4.1.34). http://purl.obolibrary.org/obo/CL_0001066 erythroid progenitor cell, mammalian http://purl.obolibrary.org/obo/CL_0000038 erythroid progenitor cell A progenitor cell committed to the erythroid lineage. This cell is ter119-positive but lacks expression of other hematopoietic lineage markers (lin-negative). http://purl.obolibrary.org/obo/CL_0008017 adult skeletal muscle myoblast http://purl.obolibrary.org/obo/CL_0000515 skeletal muscle myoblast A skeletal muscle myoblast that is part of a skeletal mucle. These cells are formed following acivation and division of skeletal muscle satellite cells. They form a transient population that is lost when they fuse to form skeletal muscle fibers. http://purl.obolibrary.org/obo/CL_0008019 mesenchymal cell http://purl.obolibrary.org/obo/CL_0000219 motile cell A non-polarised cell precursor cell that is part of some mesenchyme, is associated with the cell matrix but is not connected to other cells and is capable of migration. http://purl.obolibrary.org/obo/CL_0008022 endocardial cushion cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte A mesenchymal cell of the endocardial cushion. These cells develop via an epithelial to mesenchymal transition when endocardial cells break cell-to-cell contacts and migrate into the cardiac jelly. Cells from this population form the heart septa and valves. http://purl.obolibrary.org/obo/CL_0008025 noradrenergic neuron http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron A neuron that release noradrenaline (noriphinephrine) as a neurotransmitter. http://purl.obolibrary.org/obo/CL_0011007 paraxial cell http://purl.obolibrary.org/obo/CL_0000222 mesodermal cell A cell in the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. The cells of this region give rise to somites. http://purl.obolibrary.org/obo/CL_0011012 neural crest cell http://purl.obolibrary.org/obo/CL_0002321 embryonic cell (metazoa) A cell of the neural crest. Neural crest cells are multipotent. Premigratory neural crest cells are found at the neural plate boarder, some of which will undergo ectomesynchymal transition and delamination to form migratory neural crest cells. http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell http://purl.obolibrary.org/obo/CL_0000071 blood vessel endothelial cell Any blood vessel endothelial cell that is part of a dermis. http://purl.obolibrary.org/obo/CL_2000013 fibroblast of skin of abdomen http://purl.obolibrary.org/obo/CL_0002620 skin fibroblast Any skin fibroblast that is part of a skin of abdomen. http://purl.obolibrary.org/obo/CL_2000016 lung microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any lung endothelial cell that is part of a microvascular endothelium. http://purl.obolibrary.org/obo/CL_2000019 compound eye photoreceptor cell http://purl.obolibrary.org/obo/CL_0000287 eye photoreceptor cell Any photoreceptor cell that is part of a compound eye. http://purl.obolibrary.org/obo/CL_2000020 inner cell mass cell http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell Any native cell that is part of a inner cell mass. http://purl.obolibrary.org/obo/CL_2000022 cardiac septum cell http://purl.obolibrary.org/obo/CL_0002494 cardiocyte Any native cell that is part of a cardiac septum. http://purl.obolibrary.org/obo/CL_2000025 spinal cord oligodendrocyte http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte Any oligodendrocyte that is part of a spinal cord. http://purl.obolibrary.org/obo/CL_2000027 cerebellar basket cell http://purl.obolibrary.org/obo/CL_0000118 basket cell A GABAergic inhibitory interneuron located in the molecular layer of the cerebellar cortex. It projects axons that form specialized synaptic structures around Purkinje cells, including pericellular baskets, which wrap around the Purkinje cell soma, and the pinceau: a brush-like terminal that contacts the initial segment of the Purkinje cell axon. The basket cell modulates Purkinje cell activity through both chemical (GABAergic) and non-synaptic (ephaptic) mechanisms. It is arranged in sagittal rows that align with Purkinje cell zones, contributing to the cerebellum's modular and topographically organized architecture. It plays an essential role in regulating motor coordination and potentially cognitive functions. http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron http://purl.obolibrary.org/obo/CL_1001611 cerebellar neuron Any glutamatergic neuron that is part of a cerebellum. http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron Any neuron that is part of a central nervous system. http://purl.obolibrary.org/obo/CL_2000030 hypothalamus cell http://purl.obolibrary.org/obo/CL_0002319 neural cell Any native cell that is part of a hypothalamus. http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that is part of a peripheral nervous system. http://purl.obolibrary.org/obo/CL_2000042 embryonic fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a embryo. http://purl.obolibrary.org/obo/CL_2000044 brain microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a brain. http://purl.obolibrary.org/obo/CL_2000046 ventricular cardiac muscle cell http://purl.obolibrary.org/obo/CL_0000746 cardiac muscle cell Any cardiac muscle cell that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/CL_2000047 brainstem motor neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any motor neuron that is part of a brainstem. http://purl.obolibrary.org/obo/CL_2000063 ovarian fibroblast http://purl.obolibrary.org/obo/CL_0002132 stromal cell of ovary Any fibroblast that is part of a female gonad. http://purl.obolibrary.org/obo/CL_2000066 cardiac ventricle fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac ventricle. http://purl.obolibrary.org/obo/CL_2000067 cardiac atrium fibroblast http://purl.obolibrary.org/obo/CL_0002548 fibroblast of cardiac tissue Any fibroblast that is part of a cardiac atrium. http://purl.obolibrary.org/obo/CL_2000068 pericardium fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast Any fibroblast that is part of a pericardium. http://purl.obolibrary.org/obo/CL_2000070 optic choroid fibroblast http://purl.obolibrary.org/obo/CL_0000348 choroidal cell of the eye Any fibroblast that is part of a optic choroid. http://purl.obolibrary.org/obo/CL_2000072 adipose microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000008 microvascular endothelial cell Any microvascular endothelial cell that is part of a adipose tissue. http://purl.obolibrary.org/obo/CL_2000073 migratory cardiac neural crest cell http://purl.obolibrary.org/obo/CL_0000333 migratory neural crest cell Any migratory neural crest cell that is part of a cardiac neural crest. http://purl.obolibrary.org/obo/CL_2000080 mesenchymal stem cell of abdominal adipose tissue http://purl.obolibrary.org/obo/CL_0002570 mesenchymal stem cell of adipose tissue Any mesenchymal stem cell of adipose tissue that is part of an abdomen. http://purl.obolibrary.org/obo/CL_2000086 neocortex basket cell http://purl.obolibrary.org/obo/CL_0010011 cerebral cortex GABAergic interneuron Any basket cell that is part of a neocortex. http://purl.obolibrary.org/obo/CL_2000093 bronchus fibroblast of lung http://purl.obolibrary.org/obo/CL_0002553 fibroblast of lung Any fibroblast of lung that is part of a bronchus. http://purl.obolibrary.org/obo/CL_2000097 midbrain dopaminergic neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron Any dopaminergic neuron that is part of a midbrain. http://purl.obolibrary.org/obo/UBERON_0034995 jaw mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme Mesenchyme that is part of a developing jaw [Automatically generated definition]. http://purl.obolibrary.org/obo/UBERON_0035553 left cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the left side of the heart. http://purl.obolibrary.org/obo/UBERON_0035554 right cardiac chamber http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Any chamber of the right side of the heart. http://purl.obolibrary.org/obo/UBERON_0035639 ocular adnexa http://purl.obolibrary.org/obo/UBERON_0034921 multi organ part structure The parts of the orbital region that are outside of the the eyeball, including the lacrimal apparatus, the extraocular muscles and the eyelids, eyelashes, eyebrows and the conjunctiva. http://purl.obolibrary.org/obo/UBERON_0035804 future mouth http://purl.obolibrary.org/obo/UBERON_0013522 subdivision of tube The primordial mouth region of the developing head. http://purl.obolibrary.org/obo/UBERON_0035820 peritoneal sac http://purl.obolibrary.org/obo/UBERON_0005906 serous sac A serous sac that is the aggregate of the peritoneum and the peritoneal cavity, located in the abdominal cavity. http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization http://purl.obolibrary.org/obo/GO_0032879 regulation of localization Any process that modulates the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_1905953 negative regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_1905954 positive regulation of lipid localization http://purl.obolibrary.org/obo/GO_1905952 regulation of lipid localization Any process that activates or increases the frequency, rate or extent of lipid localization. http://purl.obolibrary.org/obo/GO_0140053 mitochondrial gene expression http://purl.obolibrary.org/obo/GO_0010467 gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. http://purl.obolibrary.org/obo/GO_0106027 neuron projection organization http://purl.obolibrary.org/obo/GO_0120036 plasma membrane bounded cell projection organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. http://purl.obolibrary.org/obo/GO_0110021 cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0051450 myoblast proliferation The multiplication or reproduction of cardiac muscle myoblasts, resulting in the expansion of a cardiac muscle myoblast cell population. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life. http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_2000291 regulation of myoblast proliferation Any process that modulates the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/GO_0110023 negative regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/GO_0110024 positive regulation of cardiac muscle myoblast proliferation http://purl.obolibrary.org/obo/GO_0110022 regulation of cardiac muscle myoblast proliferation Any process that activates or increases the frequency, rate or extent of cardiac muscle myoblast proliferation. http://purl.obolibrary.org/obo/UBERON_0036225 respiratory system gland http://purl.obolibrary.org/obo/UBERON_0002530 gland Any gland that is part os the respiratory system. http://purl.obolibrary.org/obo/GO_0120111 neuron projection cytoplasm http://purl.obolibrary.org/obo/GO_0032838 plasma membrane bounded cell projection cytoplasm All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. http://purl.obolibrary.org/obo/PATO_0045050 normal size http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A size quality which is relatively normal or average http://purl.obolibrary.org/obo/CHEBI_139512 EC 1.3.1.9 [enoyl-[acyl-carrier-protein] reductase (NADH)] inhibitor http://purl.obolibrary.org/obo/CHEBI_76857 EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of enoyl-[acyl-carrier-protein] reductase (NADH), EC 1.3.1.9. http://purl.obolibrary.org/obo/GO_0061971 replacement bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. http://purl.obolibrary.org/obo/GO_0061972 dermal bone morphogenesis http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis The process in which bone which forms superficially in the organism are generated and organized. http://purl.obolibrary.org/obo/GO_0061973 membrane bone morphogenesis http://purl.obolibrary.org/obo/GO_0060349 bone morphogenesis The process in which bone which forms deep in the organism are generated and organized. http://purl.obolibrary.org/obo/GO_0140513 nuclear protein-containing complex http://purl.obolibrary.org/obo/GO_0032991 protein-containing complex A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. http://purl.obolibrary.org/obo/GO_0140546 defense response to symbiont http://purl.obolibrary.org/obo/GO_0098542 defense response to other organism Reactions triggered in response to the presence of a symbiont that act to protect or prevent damage to the host. http://purl.obolibrary.org/obo/PHIPO_0001205 abnormal filament morphology http://purl.obolibrary.org/obo/PHIPO_0001221 abnormal anatomical structure physical quality phenotype A single species phenotype where the morphology of a cell is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001206 normal filament morphology http://purl.obolibrary.org/obo/PHIPO_0001376 normal anatomical structure physical quality phenotype A single species phenotype where the morphology of a cell is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001207 normal filament length http://purl.obolibrary.org/obo/PHIPO_0001206 normal filament morphology A single species cell morphology phenotype where the length of hyphal filaments are normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001208 unicellular colony morphology phenotype http://purl.obolibrary.org/obo/PHIPO_0000509 population phenotype A single species population phenotype affecting the morphology of a colony of unicellular individuals. http://purl.obolibrary.org/obo/PHIPO_0001210 normal hyphal growth http://purl.obolibrary.org/obo/PHIPO_0001214 hyphal growth phenotype An individual organism growth phenotype in which the size or extent of directional growth of hyphae is normal. http://purl.obolibrary.org/obo/PHIPO_0001212 decreased hyphal growth http://purl.obolibrary.org/obo/PHIPO_0001215 abnormal hyphal growth An individual organism growth phenotype in which the growth of hyphae is decreased. http://purl.obolibrary.org/obo/PHIPO_0001213 abolished hyphal growth http://purl.obolibrary.org/obo/PHIPO_0001212 decreased hyphal growth An individual organism growth phenotype in which the growth of hyphae is abolished (it was present and is now absent). http://purl.obolibrary.org/obo/PHIPO_0001214 hyphal growth phenotype http://purl.obolibrary.org/obo/PHIPO_0000402 individual organism phenotype A single species growth phenotype which affects or involves normal or abnormal size, extent or rate of directional growth of the hyphae of an individual organism. http://purl.obolibrary.org/obo/PHIPO_0001215 abnormal hyphal growth http://purl.obolibrary.org/obo/PHIPO_0001214 hyphal growth phenotype An individual organism growth phenotype in which the size or extent of directional growth of hyphae is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001216 nutrient phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A growth phenotype which describes the change or absence of change of individuals or populations (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus. http://purl.obolibrary.org/obo/PHIPO_0001217 stress phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A growth phenotype which describes the sensitivity, resistance or absence of change of individuals or populations after exposure to a specific stress. http://purl.obolibrary.org/obo/PHIPO_0001218 chemical phenotype http://purl.obolibrary.org/obo/PHIPO_0000002 single species phenotype A growth phenotype which describes the sensitivity, resistance or absence of change of individuals or populations after exposure to a specific chemical. http://purl.obolibrary.org/obo/CL_4023069 medial ganglionic eminence derived GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023063 medial ganglionic eminence derived interneuron A GABAergic interneuron that develops from the medial ganglionic eminence and has migrated to the cerebral cortex. http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A transcriptomically distinct sst GABAergic interneuron that also expresses Chodl. These neurons are rare and correspond to the only known interneurons with long-range projection. http://purl.obolibrary.org/obo/UBERON_8410081 blood microvessel http://purl.obolibrary.org/obo/UBERON_0010523 microcirculatory vessel Any of the smallest blood vessels where blood circulates within organ tissues. Microvessels include terminal arterioles, metarterioles, capillaries, and venules (but exclude lymphatic capillaries). Arterioles carry oxygenated blood to the capillaries, and blood flows out of the capillaries through venules into veins. http://purl.obolibrary.org/obo/GO_0120331 endothelial tube formation http://purl.obolibrary.org/obo/GO_0072175 epithelial tube formation The developmental process pertaining to the initial formation of an endothelial tube. http://purl.obolibrary.org/obo/CL_4023168 somatosensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron that is part of the somatic sensory system. Somatosensory neurons innervate the skin or integument to detect different types of thermal, chemical, and mechanical touch stimuli. http://purl.obolibrary.org/obo/CL_4023079 midbrain-derived inhibitory neuron http://purl.obolibrary.org/obo/CL_2000029 central nervous system neuron A GABAergic inhibitory neuron that is derived from the midbrain. http://purl.obolibrary.org/obo/GO_0170033 L-amino acid metabolic process http://purl.obolibrary.org/obo/GO_1901605 alpha-amino acid metabolic process The chemical reactions and pathways involving an L-amino acid. http://purl.obolibrary.org/obo/GO_0170041 non-proteinogenic amino acid metabolic process http://purl.obolibrary.org/obo/GO_0006520 amino acid metabolic process The chemical reactions and pathways involving non-proteingenic amino acids. http://purl.obolibrary.org/obo/GO_0170036 import into the mitochondrion http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport The directed movement of substances from the cytosol into the mitochondrion. http://purl.obolibrary.org/obo/GO_0170037 export from the mitochondrion http://purl.obolibrary.org/obo/GO_1990542 mitochondrial transmembrane transport The directed movement of substances from the mitochondrion to the cytosol. http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Anln (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1184 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307084 CHOR NN_1 Tbc1d1 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus), Tbc1d1 (Mmus). It is distinguished from other CHOR NN cells by expression of Tbc1d1. These cells are located in the Cerebellum, brain , in or close to the regions: Paraflocculus, choroid plexus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5264 CHOR NN_1. http://purl.obolibrary.org/obo/CL_4304384 hypothalamic gonadotropin-releasing hormone neuron (Mmus) http://purl.obolibrary.org/obo/CL_0011111 hypothalamic gonadotropin-releasing hormone neuron A hypothalamic gonadotropin-releasing hormone neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gnrh1 (Mmus). It is glutamatergic (inferred from expression of Gad1, Slc17a6, Gad2). These cells are located in the Hypothalamus, Olfactory areas, Pallidum, brain , in or close to the regions: Lateral septal nucleus, rostral (rostroventral) part, Medial septal nucleus, Diagonal band nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:2564 HY Gnrh1 Glut_1. http://purl.obolibrary.org/obo/CL_4307134 BAM NN_1 Fos border associated macrophage (Mmus) http://purl.obolibrary.org/obo/CL_4301625 border associated macrophage (Mmus) A border associated macrophage of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mrc1 (Mmus), Pf4 (Mmus), Fos (Mmus). It is distinguished from other BAM NN cells by expression of Fos. These cells are located in the Isocortex, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5314 BAM NN_1. http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron http://purl.obolibrary.org/obo/CL_0000617 GABAergic neuron A neuron that releases both gamma-aminobutyric acid and acetylcholine as vesicular neurotransmitters. Examples include some types of striatal interneuron. http://purl.obolibrary.org/obo/CL_0008059 GABA-Gly neuron http://purl.obolibrary.org/obo/CL_1001509 glycinergic neuron A neuron that releases both gamma-aminobutyric acid and glycine as vesicular neurotransmitters. Examples include types of amacrine cell and types of cerebellar inhibitory neurons. http://purl.obolibrary.org/obo/CL_4307090 OPC NN_1 Rmi2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Rmi2 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Rmi2, Col27a1. These cells are located in the Hypothalamus, Midbrain, Pallidum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5270 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307005 CB PLI GABA Ly6d Purkinje layer interneuron http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ly6d (Mmus), Kit (Mmus). It is distinguished from other CB PLI Gly-Gaba cells by expression of Ly6d. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain , in or close to the regions: arbor vitae, Interposed nucleus, Nodulus (X) . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5185 CB PLI Gly-Gaba_4. http://purl.obolibrary.org/obo/CL_4307042 Astro-TE NN_2 Clstn2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301592 Astro-TE NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gm6145 (Mmus), E330013P04Rik (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN_2 cells by expression of Clstn2. These cells are located in the Hippocampal region , in or close to the regions: Dentate gyrus, molecular layer, Dentate gyrus, polymorph layer, Field CA3, stratum oriens, Dentate gyrus, granule cell layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5222 Astro-TE NN_2. http://purl.obolibrary.org/obo/CL_4300354 cerebellar granule cell (Mmus) http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) A cerebellar granule cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Ror1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:314 CB Granule Glut. http://purl.obolibrary.org/obo/PHIPO_0001444 sensitive to heat stress http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress a cell phenotype in which cells grow to a lower extent than wild type following exposure to heat. http://purl.obolibrary.org/obo/CL_4307026 Bergmann glial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000644 Bergmann glial cell A Bergmann glial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr37l1 (Mmus), Ctxn3 (Mmus). It is distinguished from other Astro-Epen cells by expression of Gpr37l1, Ctxn3. These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5206 Bergmann NN_1. http://purl.obolibrary.org/obo/CL_4307012 CBX MLI Cdh22 Gaba molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cdh1 (Mmus), Acvr1c (Mmus), Adamts15 (Mmus), Pax2 (Mmus). It is distinguished from other CB GABA cells by expression of Cdh1, Acvr1c, Adamts15, Pax2. It is GABAergic (inferred from expression of Gad1, Gad2, Slc32a1). These cells are located in the Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5192 CBX MLI Cdh22 Gaba_1. http://purl.obolibrary.org/obo/CL_4300358 subcortical astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcriptomically defined type of astrocyte located predominantly in the ventral and posterior subcortical areas. It is distinguished from other cells in the brain by selective expression of Aqp4 (Mmus), Cd38 (Mmus), Agt (Mmus), Itih3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:318 Astro-NT NN. http://purl.obolibrary.org/obo/CL_4072002 myelin-forming oligodendrocyte http://purl.obolibrary.org/obo/UBERON_0004121 ectoderm-derived structure A postmitotic and differentiated oligodendrocyte derived from a oligodendrocyte progenitor cell. A myelin-forming oligodendrocyte begins the expression of myelin genes and actively engages in the myelination process. In mice and humans, it is characterized by the upregulation of the key myelin-associated markers Mbp and Opalin. Additionally, Ctps (CTP synthase) shows peak expression at this stage, suggesting a heightened demand for nucleotide biosynthesis during membrane expansion and myelin production. http://purl.obolibrary.org/obo/GO_0098690 glycinergic synapse http://purl.obolibrary.org/obo/GO_0045202 synapse A synapse that uses glycine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120035 regulation of plasma membrane bounded cell projection organization Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120033 negative regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/GO_0120034 positive regulation of plasma membrane bounded cell projection assembly http://purl.obolibrary.org/obo/GO_0120032 regulation of plasma membrane bounded cell projection assembly Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. http://purl.obolibrary.org/obo/CHEBI_137419 secondary ammonium ion http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An organic cation obtained by protonation of any secondary amino compound; major species at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_137598 4-aminosalicylate(1-) http://purl.obolibrary.org/obo/CHEBI_22494 aminobenzoate An aminobenzoate that is the conjugate base of 4-aminosalicylic acid, obtained by deprotonation of the carboxy group. Major miscrospecies at pH 7.3. http://purl.obolibrary.org/obo/CHEBI_137982 tertiary ammonium ion http://purl.obolibrary.org/obo/CHEBI_25697 organic cation An organic cation obtained by protonation of the amino group of any tertiary amino compound. http://purl.obolibrary.org/obo/CHEBI_138675 gas molecular entity http://purl.obolibrary.org/obo/CHEBI_33579 main group molecular entity Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0°C and 100 kPa). http://purl.obolibrary.org/obo/GO_0140131 positive regulation of lymphocyte chemotaxis http://purl.obolibrary.org/obo/GO_1901623 regulation of lymphocyte chemotaxis Any process that activates or increases the frequency, rate or extent of lymphocyte chemotaxis. http://purl.obolibrary.org/obo/UBERON_0036264 zygomaticotemporal nerve http://purl.obolibrary.org/obo/UBERON_0011779 nerve of head region The zygomaticotemporal nerve or zygomaticotemporal branch (temporal branch) is derived from the maxillary branch of the trigeminal nerve (Cranial nerve V). It runs along the lateral wall of the orbit in a groove in the zygomatic bone, receives a branch of communication from the lacrimal, and passes through zygomaticotemporal foramen in the zygomatic bone to enter the temporal fossa. It ascends between the bone, and substance of the Temporalis muscle, pierces the temporal fascia about 2.5 cm. above the zygomatic arch, and is distributed to the skin of the side of the forehead, and communicates with the facial nerve and with the auriculotemporal branch of the mandibular nerve. As it pierces the temporal fascia, it gives off a slender twig, which runs between the two layers of the fascia to the lateral angle of the orbit. http://purl.obolibrary.org/obo/GO_0140318 protein transporter activity http://purl.obolibrary.org/obo/GO_0005215 transporter activity Directly binding to a specific protein and delivering it to a specific cellular location. http://purl.obolibrary.org/obo/GO_0110141 L-glutamate import into mitochondrion http://purl.obolibrary.org/obo/GO_0015813 L-glutamate transmembrane transport The process in which L-glutamate is transported from the cytosol into the mitochondrial matrix. http://purl.obolibrary.org/obo/GO_0150102 negative regulation of monocyte activation http://purl.obolibrary.org/obo/GO_0002695 negative regulation of leukocyte activation Any process that stops, prevents or reduces the frequency, rate or extent of monocyte activation. http://purl.obolibrary.org/obo/GO_0120222 regulation of blastocyst development http://purl.obolibrary.org/obo/GO_0050793 regulation of developmental process Any process that modulates the frequency, rate or extent of blastocyst development. http://purl.obolibrary.org/obo/GO_0106259 symbiont-mediated cell-to-cell migration in host http://purl.obolibrary.org/obo/GO_0044001 migration in host The directional movement of a symbiont from one host cell to another. http://purl.obolibrary.org/obo/UBERON_8000006 left side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Left part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/UBERON_8000007 right side of back http://purl.obolibrary.org/obo/UBERON_0015212 lateral structure Right part of the organism dorsal to a horizontal plane and bounded on one side by the same transverse plane. http://purl.obolibrary.org/obo/CHEBI_176497 geroprotector http://purl.obolibrary.org/obo/CHEBI_50267 protective agent Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. http://purl.obolibrary.org/obo/GO_0140694 membraneless organelle assembly http://purl.obolibrary.org/obo/GO_0070925 organelle assembly The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle. http://purl.obolibrary.org/obo/CL_4023097 arachnoid barrier cell http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx A mesothelial fibroblast of the arachnoid barrier layer. Arachnoid barrier cells make up the tight-junctioned layer in the leptomeninx that functions as the physiologic barrier between the cerebrospinal fluid in the subarachnoid space and the fenestrated capillaries in the dura. http://purl.obolibrary.org/obo/CL_4023111 cerebral cortex pyramidal neuron http://purl.obolibrary.org/obo/CL_0010012 cerebral cortex neuron A pyramidal neuron with soma located in the cerebral cortex. http://purl.obolibrary.org/obo/UBERON_8450002 excretory system http://purl.obolibrary.org/obo/UBERON_0000467 anatomical system An anatomical system that eliminates waste products that arise as a result of metabolic activity. http://purl.obolibrary.org/obo/UBERON_8480029 skin of external genitalia http://purl.obolibrary.org/obo/UBERON_0005156 reproductive structure A zone of skin that is part of the external genitalia. http://purl.obolibrary.org/obo/CL_4033049 taste receptor cell of tongue http://purl.obolibrary.org/obo/CL_0002319 neural cell A taste receptor cell that is part of a taste bud of a tongue. http://purl.obolibrary.org/obo/CL_4033050 catecholaminergic neuron http://purl.obolibrary.org/obo/CL_0000540 neuron A neuron that releases catecholamine as a neurotransmitter. http://purl.obolibrary.org/obo/GO_0160307 protein biosynthetic process http://purl.obolibrary.org/obo/GO_0006412 translation The chemical reactions and pathways resulting in the formation of protein. http://purl.obolibrary.org/obo/CL_4072001 newly formed oligodendrocyte http://purl.obolibrary.org/obo/CL_0000128 oligodendrocyte A post-mitotic oligodendrocyte that has exited the cell cycle and begun early stage differentiation. The cell begins to acquire oligodendrocyte-like characteristics but has not yet initiated myelination. In mice, NFOL is marked by the expression of Tcf7l2 and Cemip2 (also known as Tmem2), among other early myelin-related genes. These markers highlight cells transitioning from a precursor to a more differentiated, pre-myelinating state. http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) http://purl.obolibrary.org/obo/CL_2000028 cerebellum glutamatergic neuron A cerebellum glutamatergic neuron of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:29 CB Glut. http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) http://purl.obolibrary.org/obo/CL_0000255 eukaryotic cell A cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Class:31 OPC-Oligo. http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) http://purl.obolibrary.org/obo/CL_0000127 astrocyte A transcritpomically defined type of astrocytes primarily restricted to the dorsal regions of the cerebrum. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Lhx2 (Mmus), Gpc5 (Mmus), Nr2f1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:319 Astro-TE NN. http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_0002085 tanycyte A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr50 (Mmus), Apoe (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:322 Tanycyte NN. http://purl.obolibrary.org/obo/CL_4300363 ependymal cell (Mmus) http://purl.obolibrary.org/obo/CL_0000065 ependymal cell A ependymal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Tmem212 (Mmus), Rarres2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:323 Ependymal NN. http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300031 OPC-Oligo cell (Mmus) A oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Gjc3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:327 Oligo NN. http://purl.obolibrary.org/obo/CL_4300370 VLMC NN vascular leptomeningeal cell (Mmus) http://purl.obolibrary.org/obo/CL_4023051 vascular leptomeningeal cell A vascular leptomeningeal cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Slc6a13 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Subclass:330 VLMC NN. http://purl.obolibrary.org/obo/CL_4301573 DCO Il22 Gly-Gaba_3 cerebellar neuron (Mmus) http://purl.obolibrary.org/obo/CL_4300348 DCO Il22 Gly-Gaba cerebellar neuron (Mmus) A cerebellar neuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fat2 (Mmus), Slc6a5 (Mmus), Cgnl1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1143 DCO Il22 Gly-Gaba_3. http://purl.obolibrary.org/obo/CL_4301576 CB PLI Gly-Gaba_3 Purkinje layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300349 Purkinje layer interneuron (Mmus) A Purkinje layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pax2 (Mmus), C1ql3 (Mmus), Tfap2b (Mmus), Gabrb1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1146 CB PLI Gly-Gaba_3. http://purl.obolibrary.org/obo/CL_4301578 cerebellar Golgi cell (Mmus) http://purl.obolibrary.org/obo/CL_4300028 cerebellar GABAergic neuron (Mmus) A cerebellar Golgi cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Zfp385c (Mmus), Tfap2b (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1148 CBX Golgi Gly-Gaba_1. http://purl.obolibrary.org/obo/CL_4301580 CBX MLI Megf11 Gaba_2 molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gabra6 (Mmus), Pvalb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1150 CBX MLI Megf11 Gaba_2. http://purl.obolibrary.org/obo/CL_4301583 CBX Purkinje Gaba_2 Purkinje cell (Mmus) http://purl.obolibrary.org/obo/CL_4300353 Purkinje cell (Mmus) A Purkinje cell of the Mus musculus brain. Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1153 CBX Purkinje Gaba_2. http://purl.obolibrary.org/obo/CL_4301586 unipolar brush cell (Mmus) http://purl.obolibrary.org/obo/CL_4300029 cerebellar glutamatergic neuron (Mmus) A unipolar brush cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Sln (Mmus), Lmx1a (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1156 DCO UBC Glut_1. http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Grin2c (Mmus), Dcc (Mmus), Slc7a10 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1163 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Thbs4 (Mmus), Kcnk10 (Mmus), Pak1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1165 Astro-TE NN_5. http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300360 olfactory areas astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Hs3st3a1 (Mmus), Slco1c1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1167 Astro-OLF NN_2. http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Lpl (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1172 Tanycyte NN_1. http://purl.obolibrary.org/obo/CL_4301608 choroid plexus epithelial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000706 choroid plexus epithelial cell A choroid plexus epithelial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 2900040C04Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1178 CHOR NN_1. http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ptprb (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1182 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300367 oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), Sec14l5 (Mmus), 9630013A20Rik (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1183 MFOL NN_3. http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_0011028 olfactory ensheathing cell A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Npy (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1185 OEC NN_1. http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4023097 arachnoid barrier cell A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Thbd (Mmus), Ccn3 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1186 ABC NN_1. http://purl.obolibrary.org/obo/CL_4307027 cerebellar astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_0002603 astrocyte of the cerebellum A transcriptomically defined type of astrocyte localized exclusively in the cerebellum beneath the Purkinje cell layer. It is distinguished from other cells in the brain by selective expression of Dao (Mmus), Efemp1 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5207 Astro-CB NN_1. http://purl.obolibrary.org/obo/CL_4307029 Astro-NT NN_1 Slc36a2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301589 Astro-NT NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Slc36a2 (Mmus), Sfrp5 (Mmus). It is distinguished from other Astro-NT NN_1 cells by expression of Slc36a2, Sfrp5. These cells are located in the Midbrain, Cerebellum, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5209 Astro-NT NN_1. http://purl.obolibrary.org/obo/CL_4307034 Astro-NT NN_2 Fzd2 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301590 Astro-NT NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), A330076C08Rik (Mmus), Sfrp5 (Mmus), Gria2 (Mmus). It is distinguished from other Astro-NT NN_2 cells by expression of Fzd2, Gria2, Ttll3. These cells are located in the Midbrain, Thalamus, Pons , in or close to the regions: Midbrain reticular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5214 Astro-NT NN_2. http://purl.obolibrary.org/obo/CL_4307038 Astro-TE NN_1 Myoc astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Myoc (Mmus), Lhx2 (Mmus), Kcne1l (Mmus), Alpk1 (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Myoc, Kcne1l, Alpk1. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5218 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307039 Astro-TE NN_1 Rasl10b astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301591 Astro-TE NN_1 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gfap (Mmus), Ddn (Mmus), Myoc (Mmus), Rasl10b (Mmus). It is distinguished from other Astro-TE NN_1 cells by expression of Rasl10b, Igfbp5. These cells are located in the Hippocampal region, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5219 Astro-TE NN_1. http://purl.obolibrary.org/obo/CL_4307044 Astro-TE NN_3 Cxcl5 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gja1 (Mmus), Cxcl5 (Mmus), Ddn (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Cxcl5, Kif5a. These cells are located in the Hippocampal region, Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5224 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4307045 Astro-TE NN_3 Fam163a astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Fam163a (Mmus), Kcnq3 (Mmus), Kcnq1ot1 (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Fam163a, Nr2f1, Kcnq1ot1. These cells are located in the Isocortex, Olfactory areas . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5225 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4307047 Astro-TE NN_3 Crym astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301593 Astro-TE NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Crym (Mmus), Grin2c (Mmus). It is distinguished from other Astro-TE NN_3 cells by expression of Crym, Gabbr2. These cells are located in the Striatum dorsal region, Striatum ventral region , in or close to the regions: Nucleus accumbens, Caudoputamen . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5227 Astro-TE NN_3. http://purl.obolibrary.org/obo/CL_4307048 Astro-TE NN_4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4300359 astrocyte of cerebrum (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Thbs4 (Mmus), Gm29683 (Mmus), Slc39a12 (Mmus). It is distinguished from other Astro-TE NN cells by expression of Gm29683. These cells are located in the Cortical subplate, brain , in or close to the regions: Lateral amygdalar nucleus, external capsule . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5228 Astro-TE NN_4. http://purl.obolibrary.org/obo/CL_4307050 Astro-TE NN_5 Adamts18 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301595 Astro-TE NN_5 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Adamts18 (Mmus), Crym (Mmus). It is distinguished from other Astro-TE NN_5 cells by expression of Adamts18. These cells are located in the Lateral septal complex, Striatum dorsal region, brain , in or close to the regions: Nucleus accumbens, Caudoputamen, lateral ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5230 Astro-TE NN_5. http://purl.obolibrary.org/obo/CL_4307054 Astro-OLF NN_2 Alk astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301597 Astro-OLF NN_2 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), Chrdl1 (Mmus), Sfrp1 (Mmus), Atp13a4 (Mmus). It is distinguished from other Astro-OLF NN_2 cells by expression of Alk, Atp13a4. These cells are located in the Olfactory areas , in or close to the regions: Anterior olfactory nucleus, Main olfactory bulb, granule layer, Main olfactory bulb, mitral layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5234 Astro-OLF NN_2. http://purl.obolibrary.org/obo/CL_4307055 Astro-OLF NN_3 Ecrg4 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Dipk1c (Mmus), Ecrg4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Ecrg4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5235 Astro-OLF NN_3. http://purl.obolibrary.org/obo/CL_4307056 Astro-OLF NN_3 Sfrp1 astrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301598 Astro-OLF NN_3 astrocyte (Mmus) A astrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of S1pr1 (Mmus), 6530411M01Rik (Mmus), Sfrp1 (Mmus), Aqp4 (Mmus). It is distinguished from other Astro-OLF NN_3 cells by expression of Sfrp1, Aqp4. These cells are located in the Olfactory areas , in or close to the regions: Main olfactory bulb, granule layer, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5236 Astro-OLF NN_3. http://purl.obolibrary.org/obo/CL_4307063 Tanycyte NN_1 Cnmd tanycyte of subfornical organ (Mmus) http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) A tanycyte of subfornical organ of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cnmd (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Cnmd. These cells are located in the brain , in or close to the regions: choroid plexus, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5243 Tanycyte NN_1. http://purl.obolibrary.org/obo/CL_4307064 Tanycyte NN_1 Glp1r tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301602 Tanycyte NN_1 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C230072F16Rik (Mmus), Glp1r (Mmus). It is distinguished from other Tanycyte NN_1 cells by expression of Glp1r. These cells are located in the Hypothalamus, brain , in or close to the regions: Anteroventral periventricular nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5244 Tanycyte NN_1. http://purl.obolibrary.org/obo/CL_4307065 Tanycyte NN_2 Mylk3 alpha1-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dynlrb2 (Mmus), Mylk3 (Mmus), Sfta3-ps (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mylk3. It is glutamatergic (inferred from expression of Slc17a8). These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5245 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307066 Tanycyte NN_2 Mroh5 alpha1-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha1-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc170 (Mmus), Nkx2-4 (Mmus), Dock8 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Mroh5. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, intermediate part, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5246 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307067 alpha2-tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A alpha2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdzph1 (Mmus), Wdr63 (Mmus), Dscaml1 (Mmus), P3h2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Dscaml1, P3h2. These cells are located in the Hypothalamus , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5247 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307068 Tanycyte NN_2 Otx2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4301603 Tanycyte NN_2 tanycyte (Mmus) A tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Ccdc146 (Mmus), Tbx3 (Mmus), Otx2 (Mmus). It is distinguished from other Tanycyte NN_2 cells by expression of Otx2, Nkx2-4. These cells are located in the Hypothalamus, brain , in or close to the regions: Periventricular hypothalamic nucleus, posterior part, third ventricle . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5248 Tanycyte NN_2. http://purl.obolibrary.org/obo/CL_4307070 beta-2 tanycyte (Mmus) http://purl.obolibrary.org/obo/CL_4300362 tanycyte (Mmus) A beta2-tanycyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Fndc3c1 (Mmus), Ecrg4 (Mmus). It is distinguished from other Tanycyte NN cells by expression of Ecrg4. These cells are located in the Hypothalamus, brain , in or close to the regions: Median eminence, third ventricle, Arcuate hypothalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5250 Tanycyte NN_3. http://purl.obolibrary.org/obo/CL_4307087 OPC NN_1 Irx2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Pclaf (Mmus), Irx2 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Neil3, Irx2. These cells are located in the Cerebellum, brain, Midbrain, Pons, Medulla . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5267 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307088 OPC NN_1 Mms22l oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Mms22l (Mmus), Top2a (Mmus). It is distinguished from other OPC NN_1 cells by expression of Mms22l, Foxg1, Top2a. These cells are located in the Isocortex, Olfactory areas, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5268 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307089 OPC NN_1 Col27a1 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Olig1 (Mmus), Col27a1 (Mmus). It is distinguished from other OPC NN_1 cells by expression of Col27a1. These cells are located in the Midbrain, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5269 OPC NN_1. http://purl.obolibrary.org/obo/CL_4307092 COP NN_1 Rgcc committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bmp4 (Mmus), Zfp36l1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, Plpp4. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5272 COP NN_1. http://purl.obolibrary.org/obo/CL_4307093 COP NN_1 9130019P16Rik committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Gp1bb (Mmus), Pdzd2 (Mmus), Plekhg1 (Mmus). It is distinguished from other COP NN_1 cells by expression of Rgcc, 9130019P16Rik. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5273 COP NN_1. http://purl.obolibrary.org/obo/CL_4307094 COP NN_1 C1ql1 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Gpr17 (Mmus), Bgn (Mmus), Gstp1 (Mmus), C1ql1 (Mmus). It is distinguished from other COP NN_1 cells by expression of C1ql1, Gstp1. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5274 COP NN_1. http://purl.obolibrary.org/obo/CL_4307096 COP NN_1 Vwc2 committed oligodendrocyte precursor (Mmus) http://purl.obolibrary.org/obo/CL_4301611 commited oligodendrocyte precursor (Mmus) A committed oligodendrocyte precursor of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rab32 (Mmus), Opalin (Mmus). It is distinguished from other COP NN_1 cells by expression of Vwc2, Opalin. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5276 COP NN_1. http://purl.obolibrary.org/obo/CL_4307098 NFOL NN_2 9630013A20Rik newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Grin2b (Mmus). It is distinguished from other NFOL NN_2 cells by expression of 9630013A20Rik, Grin2b. These cells are located in the Midbrain, Thalamus, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5278 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307099 NFOL NN_2 Dbx2 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Dbx2 (Mmus), Rassf10 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Dbx2, Rassf10. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5279 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307100 NFOL NN_2 Rgs16 newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Rgs16 (Mmus), Rhbdl2 (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Rgs16, Rhbdl2. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5280 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307101 NFOL NN_2 Il23a newly formed oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301612 newly formed oligodendrocyte (Mmus) A newly formed oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Piezo2 (Mmus), Ptprb (Mmus). It is distinguished from other NFOL NN_2 cells by expression of Il23a, Opalin, Ptprb. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5281 NFOL NN_2. http://purl.obolibrary.org/obo/CL_4307102 MFOL NN_3 Cxcl12 myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Cxcl12 (Mmus), Efhd1 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Cxcl12, Efhd1. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5282 MFOL NN_3. http://purl.obolibrary.org/obo/CL_4307103 MFOL NN_3 Il23a myelin-forming oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301613 myelin-forming oligodendrocyte (Mmus) A myelin-forming oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of 9630013A20Rik (Mmus), Ppp1r14a (Mmus), Mroh3 (Mmus). It is distinguished from other MFOL NN_3 cells by expression of Il23a, Ppp1r14a. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5283 MFOL NN_3. http://purl.obolibrary.org/obo/CL_4307104 MOL NN_4 Plin3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prr5l (Mmus), Hapln2 (Mmus), Enpp6 (Mmus), Grm7 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Plin3, Grm7. These cells are located in the Medulla, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5284 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307105 MOL NN_4 Spock3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Cldn11 (Mmus), A230001M10Rik (Mmus), Spock3 (Mmus), Rhoj (Mmus). It is distinguished from other MOL NN_4 cells by expression of Spock3, Rhoj. These cells are located in the Midbrain, Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5285 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307106 MOL NN_4 Art3 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Klk6 (Mmus), Dlc1 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Art3. These cells are located in the Medulla, Pons, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5286 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307107 MOL NN_4 Il33 mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Opalin (Mmus), Grm3 (Mmus), Gm5087 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Il33, Gm5087. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5287 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307108 MOL NN_4 Sspo mature myelinating oligodendrocyte (Mmus) http://purl.obolibrary.org/obo/CL_4301614 mature myelinating oligodendrocyte (Mmus) A mature myelinating oligodendrocyte of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Mog (Mmus), Anln (Mmus), Gm32633 (Mmus). It is distinguished from other MOL NN_4 cells by expression of Sspo, Selenop. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5288 MOL NN_4. http://purl.obolibrary.org/obo/CL_4307111 OEC NN_1 A330076C08Rik olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Syk (Mmus). It is distinguished from other OEC cells by expression of A330076C08Rik. These cells are located in the Olfactory areas, brain , in or close to the regions: olfactory nerve layer of main olfactory bulb, Main olfactory bulb . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5291 OEC NN_1. http://purl.obolibrary.org/obo/CL_4307112 OEC NN_1 Rasgef1c olfactory ensheathing cell (Mmus) http://purl.obolibrary.org/obo/CL_4301615 olfactory ensheathing cell (Mmus) A olfactory ensheathing cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Apod (Mmus), Mybpc1 (Mmus), Rasgef1c (Mmus). It is distinguished from other OEC cells by expression of Rasgef1c. It is glutamatergic (inferred from expression of Slc17a7). These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5292 OEC NN_1. http://purl.obolibrary.org/obo/CL_4307115 ABC NN_1 Cubn arachnoid barrier cell (Mmus) http://purl.obolibrary.org/obo/CL_4301616 arachnoid barrier cell (Mmus) A arachnoid barrier cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Prg4 (Mmus), Cubn (Mmus). It is distinguished from other ABC NN cells by expression of Cubn. These cells are located in the brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5295 ABC NN_1. http://purl.obolibrary.org/obo/CL_4307132 microglial cell (Mmus) http://purl.obolibrary.org/obo/CL_0000129 microglial cell A microglial cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of C1qa (Mmus), Tmem119 (Mmus). It is distinguished from other Immune cells by expression of C1qa, Tmem119. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5312 Microglia NN_1. http://purl.obolibrary.org/obo/PHIPO_0001441 abnormal mycotoxin biosythesis http://purl.obolibrary.org/obo/PHIPO_0001442 abnormal biological process phenotype A single organism phenotype in which an abnormal amount of mycotoxin is produced. http://purl.obolibrary.org/obo/PHIPO_0001443 abnormal deoxynivalenol biosynthesis http://purl.obolibrary.org/obo/PHIPO_0001441 abnormal mycotoxin biosythesis A single organism phenotype in which deoxynivalenol biosynthesis is abnormal. http://purl.obolibrary.org/obo/PHIPO_0001445 decreased level of deoxynivalenol http://purl.obolibrary.org/obo/PHIPO_0001031 decreased cellular toxin level A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is decreased. http://purl.obolibrary.org/obo/PHIPO_0001446 reduced hyphal branching http://purl.obolibrary.org/obo/PHIPO_0001427 abnormal hyphal branching A single species cell morphology phenotype in which fungal hyphae form a decreased number of branches. http://purl.obolibrary.org/obo/PHIPO_0001447 increased level of deoxynivalenol http://purl.obolibrary.org/obo/PHIPO_0001037 increased cellular toxin level A single species cell phenotype in which the amount of deoxynivalenol measured in a cell is increased. http://purl.obolibrary.org/obo/PHIPO_0001448 restored pathogenicity http://purl.obolibrary.org/obo/PHIPO_0000006 pathogenicity phenotype A phenotype where the ability of a pathogen to produce an infectious disease in another organism is restored (pathogenicity was present, then absent, and now present). http://purl.obolibrary.org/obo/CHEBI_141498 hemiaminal ether http://purl.obolibrary.org/obo/CHEBI_36963 organooxygen compound An organic amino compound that is a hemiaminal in which the hydrogen atom of the hydroxy group has been replaced by an organyl group. General formula: R2C(OR')NR2 ( R ≠ H ). Also known as α-amino ethers. http://purl.obolibrary.org/obo/PATO_0040003 pathogenicity http://purl.obolibrary.org/obo/PATO_0001995 organismal quality The ability of a pathogen to produce an infectious disease or disorder in an another organism. http://purl.obolibrary.org/obo/GO_0150098 glial cell-neuron signaling http://purl.obolibrary.org/obo/GO_0007267 cell-cell signaling Cell-cell signaling that mediates the transfer of information from a glial cell to a neuron. This signaling has been shown to be mediated by various molecules, depending on which glial cells release them, and in which tissues the signaling occurs, e.g. microglial cell-derived nerve growth factor (NGF) in the retina, or microglial cell-derived superoxide ions in the cerebellum. http://purl.obolibrary.org/obo/GO_0140353 lipid export from cell http://purl.obolibrary.org/obo/GO_0006869 lipid transport The directed movement of a lipid from a cell, into the extracellular region. http://purl.obolibrary.org/obo/GO_0062247 chloroplast vesicle http://purl.obolibrary.org/obo/GO_0031410 cytoplasmic vesicle A intracellular vesicle that is part of a chloroplast. http://purl.obolibrary.org/obo/PHIPO_0001204 decreased extent of host-defense induced lesion by host hypersensitive response http://purl.obolibrary.org/obo/PHIPO_0000985 decreased extent of pathogen-associated host lesions A phenotype where the process of host tissue cell death causing a host lesion is induced by the host activating its own hypersensitive response in defense to a lesser extent than normal. http://purl.obolibrary.org/obo/CL_0010017 zygote http://purl.obolibrary.org/obo/CL_0000000 cell A zygote in a plant or an animal. http://purl.obolibrary.org/obo/CL_0011027 skeletal muscle fibroblast http://purl.obolibrary.org/obo/CL_1001609 muscle fibroblast Any fibroblast that is part of skeletal muscle tissue. http://purl.obolibrary.org/obo/CL_0011028 olfactory ensheathing cell http://purl.obolibrary.org/obo/CL_0000125 glial cell A neural-crest derived glial cell that supports the growth and survival of primary olfactory neuroons from the neuroepithelium in the nasal cavity to the brain by encasing large bundles of numerous unmyelinated axons. http://purl.obolibrary.org/obo/UBERON_1100000 digestive tract junction http://purl.obolibrary.org/obo/UBERON_0007651 anatomical junction An anatomical junction between two parts of the digestive tract. http://purl.obolibrary.org/obo/GO_0140650 radial glia-guided pyramidal neuron migration http://purl.obolibrary.org/obo/GO_0001764 neuron migration The radial migration of a pyramidal neuron along radial glial cells. http://purl.obolibrary.org/obo/CL_4033008 vein endothelial cell of respiratory system http://purl.obolibrary.org/obo/CL_0002543 vein endothelial cell A(n) vein endothelial cell that is part of a(n) respiratory system. http://purl.obolibrary.org/obo/GO_0141188 nucleic acid catabolic process http://purl.obolibrary.org/obo/GO_0009057 macromolecule catabolic process The cellular DNA metabolic process resulting in the breakdown of a nucleic acid. http://purl.obolibrary.org/obo/GO_0170055 lipid transmembrane transporter activity http://purl.obolibrary.org/obo/GO_0022857 transmembrane transporter activity Enables the transfer of a lipid from one side of a membrane to the other. http://purl.obolibrary.org/obo/CL_4307091 OPC NN_2 oligodendrocyte precursor cell (Mmus) http://purl.obolibrary.org/obo/CL_4300366 oligodendrocyte precursor cell (Mmus) A oligodendrocyte precursor cell of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Pdgfra (Mmus), Cenpf (Mmus), Cenpa (Mmus). It is distinguished from other OPC NN cells by expression of Cenpa. These cells are located in the Isocortex, brain . Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Cluster:5271 OPC NN_2. http://purl.obolibrary.org/obo/CHEBI_138015 endocrine disruptor http://purl.obolibrary.org/obo/CHEBI_51061 hormone receptor modulator Any compound that can disrupt the functions of the endocrine (hormone) system http://purl.obolibrary.org/obo/GO_0110053 regulation of actin filament organization http://purl.obolibrary.org/obo/GO_0032956 regulation of actin cytoskeleton organization Any process that modulates the frequency, rate or extent of actin filament organization. http://purl.obolibrary.org/obo/PATO_0045084 normal duration http://purl.obolibrary.org/obo/PATO_0045073 normal process quality A duration quality of a process which is relatively normal. http://purl.obolibrary.org/obo/GO_0062033 positive regulation of mitotic sister chromatid segregation http://purl.obolibrary.org/obo/GO_0033047 regulation of mitotic sister chromatid segregation Any process that starts or increases the frequency, rate or extent of sister chromatid segregation during mitosis. http://purl.obolibrary.org/obo/CHEBI_142708 tigecycline(1+) http://purl.obolibrary.org/obo/CHEBI_35274 ammonium ion derivative An ammonium ion that is the conjugate acid of tigecycline; major species at pH 7.3. http://purl.obolibrary.org/obo/CL_3000004 peripheral sensory neuron http://purl.obolibrary.org/obo/CL_2000032 peripheral nervous system neuron A neuron type that is located in a peripheral nervous system and it transmits sensory information from the peripheral (PNS) to the central nervous system (CNS). A sensory neuron converts physical (light, sound, touch) or chemical (such as taste and smell) stimuli into an electrical signal through a process known as sensory transduction. The function of a sensory neuron is to carry informations from the external environment and internal body conditions to the central nervous system for further processing. http://purl.obolibrary.org/obo/CHEBI_146295 pyranobenzodioxin http://purl.obolibrary.org/obo/CHEBI_38104 oxacycle Any organic heterotricyclic compound whose core skeleton consists of a benzodioxin ring that is ortho-fused to a pyran ring. http://purl.obolibrary.org/obo/UBERON_0037144 wall of heart http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall Wall of organ which has as its parts the endocardium, myocardium , epicardium, and the cardiac septum, surrounded by the pericardial sac proper and is continuous with the walls of the systemic and pulmonary arterial and venous trees. http://purl.obolibrary.org/obo/PHIPO_0001231 host defense-induced RNA present http://purl.obolibrary.org/obo/PHIPO_0001263 host defense-induced RNA level phenotype A pathogen host interaction phenotype, in which the host RNA usually present during infection is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001232 pathogen RNA within host present http://purl.obolibrary.org/obo/PHIPO_0001267 level of pathogen produced RNA within host phenotype A pathogen host interaction phenotype, in which the level of pathogen RNA usually present during host infection is normal (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001233 pathogen inhibition of host defense induced acidification in phagolysome http://purl.obolibrary.org/obo/PHIPO_0001108 pathogen host interaction pH phenotype A pathogen host interaction phenotype where the host induced pH decrease within the host phagolysome in response to pathogen colonization is inhibited. http://purl.obolibrary.org/obo/PHIPO_0001234 increased hyphal growth http://purl.obolibrary.org/obo/PHIPO_0001215 abnormal hyphal growth An individual organism growth phenotype in which the growth of hyphae is increased. http://purl.obolibrary.org/obo/PATO_0010006 cell morphology http://purl.obolibrary.org/obo/PATO_0000051 morphology A quality of a single cell inhering in the bearer by virtue of the bearer's size or shape or structure. http://purl.obolibrary.org/obo/PATO_0070010 stellate morphology http://purl.obolibrary.org/obo/PATO_0070026 multipolar neuron morphology A cell morphology that inheres in neurons that have dendritic processes radiating from the cell body forming a star-like shape. http://purl.obolibrary.org/obo/CL_4023054 mesothelial fibroblast http://purl.obolibrary.org/obo/CL_0000057 fibroblast A mesothelial cell that has undergone mesothelial-to-mesenchymal transition (MMT) to become a fibroblast cell. http://purl.obolibrary.org/obo/PHIPO_0001342 resistance to triflumizole http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to triflumizole. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001343 sensitive to triflumizole http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to triflumizole. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001344 normal growth on triflumizole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to triflumizole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001345 resistance to bitertanol http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to bitertanol. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001346 sensitive to bitertanol http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to bitertanol. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001347 normal growth on bitertanol http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to bitertanol (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001348 resistance to pyrifenox http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to pyrifenox. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001349 sensitive to pyrifenox http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrifenox. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001350 normal growth on pyrifenox http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrifenox (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001351 normal growth on itraconazole http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to itraconazole (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001352 normal growth on amphotericin B http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to amphotericin B (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/UBERON_8600024 pulmonary venule http://purl.obolibrary.org/obo/UBERON_0003512 lung blood vessel A venule that is part of a lung and drains oxygenated blood from pulmonary capillaries. A pulmonary venule merges into a pulmonary vein branch that runs in the pulmonary interlobular septa. http://purl.obolibrary.org/obo/UBERON_8450003 embryonic craniocervical region http://purl.obolibrary.org/obo/UBERON_0007811 craniocervical region A craniocervical region that is part of an embryo. http://purl.obolibrary.org/obo/GO_0140139 solid phase of basement membrane http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The solid compartment of the basement membrane ECM, including a specific subset of basement membrane collagens and basement membrane glycoproteins like laminins or nidogens. http://purl.obolibrary.org/obo/GO_0140143 collagenous component of basement membrane http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure Collagenous component of basement membrane ECMs, including collagen IV and other types of collagen specifically expressed in basement membrane. http://purl.obolibrary.org/obo/GO_0140151 solid phase of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure The solid compartment of the interstitial matrix, including interstitial collagens such as fibrillar and fibril-associated collagens and non-collagenous glycoproteins like fibronectin and elastin. http://purl.obolibrary.org/obo/GO_0140152 collagenous component of interstitial matrix http://purl.obolibrary.org/obo/GO_0030312 external encapsulating structure Main components of the interstitial matrix solid phase, including fibrillar and fibril-associated collagens. http://purl.obolibrary.org/obo/GO_0140154 chicken-wire-like collagen network http://purl.obolibrary.org/obo/GO_0098645 collagen network Network-forming collagens can either form a chicken-wire-like network or a hexagonal network. Collagen type IV forms a chicken-wire-like structure and is found in the basement membrane. http://purl.obolibrary.org/obo/CL_4301579 CBX MLI Megf11 Gaba_1 molecular layer interneuron (Mmus) http://purl.obolibrary.org/obo/CL_4300351 CBX MLI Megf11 Gaba molecular layer interneuron (Mmus) A molecular layer interneuron of the Mus musculus brain. It is distinguished from other cells in the brain by selective expression of Dnah11 (Mmus), Sla (Mmus), Gldc (Mmus), Sdk2 (Mmus). Reference transcriptomic data for this type can be found in the dataset/taxonomy - Yao et al. (2023), Whole Mouse Brain in cell set Supertype:1149 CBX MLI Megf11 Gaba_1. http://purl.obolibrary.org/obo/GO_0061900 glial cell activation http://purl.obolibrary.org/obo/GO_0001775 cell activation A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. http://purl.obolibrary.org/obo/GO_0061919 process utilizing autophagic mechanism http://purl.obolibrary.org/obo/GO_0009987 cellular process A cellular process involving delivery of a portion of the cytoplasm to lysosomes or to the plant or fungal vacuole that does not involve direct transport through the endocytic or vacuolar protein sorting (Vps) pathways. This process typically leads to degradation of the cargo; however, it can also be used to deliver resident proteins, such as in the cytoplasm-to-vacuole targeting (Cvt) pathway. http://purl.obolibrary.org/obo/UBERON_0036217 coelomic fluid http://purl.obolibrary.org/obo/UBERON_0006314 bodily fluid A bodily fluid that is located in the coelom. http://purl.obolibrary.org/obo/UBERON_0036242 post-embryonic notochord http://purl.obolibrary.org/obo/UBERON_0002328 notochord A notochord that has persisted beyond the embryonic stage. http://purl.obolibrary.org/obo/PATO_0045088 normal sensitivity of a process http://purl.obolibrary.org/obo/PATO_0045073 normal process quality A sensitivity of a process which is relatively normal. http://purl.obolibrary.org/obo/PATO_0045010 normal concentration http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A concentration which is relatively normal or average. http://purl.obolibrary.org/obo/PATO_0045086 normal occurrence http://purl.obolibrary.org/obo/PATO_0045073 normal process quality An occurrence which is relatively normal. http://purl.obolibrary.org/obo/PATO_0045049 normal sensitivity toward http://purl.obolibrary.org/obo/PATO_0045001 normal object quality A sensitivity toward an external stimulus which is relatively normal or average http://purl.obolibrary.org/obo/GO_0140244 regulation of translation at presynapse http://purl.obolibrary.org/obo/GO_0140243 regulation of translation at synapse Any process that regulates translation occurring at the presynapse. http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_1903358 regulation of Golgi organization Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0106215 negative regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0106216 positive regulation of vesicle fusion with Golgi apparatus http://purl.obolibrary.org/obo/GO_0106214 regulation of vesicle fusion with Golgi apparatus Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0032880 regulation of protein localization Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/GO_0150107 positive regulation of protein localization to cell-cell junction http://purl.obolibrary.org/obo/GO_0150106 regulation of protein localization to cell-cell junction Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. http://purl.obolibrary.org/obo/CL_4023058 mesothelial fibroblast of the leptomeninx http://purl.obolibrary.org/obo/CL_4023054 mesothelial fibroblast A mesothelial fibroblast found in the leptomeninx. http://purl.obolibrary.org/obo/CL_0011030 dermal microvascular endothelial cell http://purl.obolibrary.org/obo/CL_2000010 dermis blood vessel endothelial cell Any microvascular endothelial cell that is part of the dermis. http://purl.obolibrary.org/obo/PHIPO_0001294 inhibition of pathogen polygalacturonase by host present http://purl.obolibrary.org/obo/PHIPO_0000347 pathogen host interaction molecular function phenotype A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen polygalacturonase is present. http://purl.obolibrary.org/obo/PHIPO_0001295 inhibition of pathogen polygalacturonase by host decreased http://purl.obolibrary.org/obo/PHIPO_0000347 pathogen host interaction molecular function phenotype A pathogen host interaction molecular function phenotype in which host-mediated inhibition of a pathogen polygalacturonase occurs to a lesser extent than normal. http://purl.obolibrary.org/obo/PHIPO_0001296 resistance to arborcandin C http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to arborcandin C. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001297 sensitive to arborcandin C http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to arborcandin C. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001298 normal growth on arborcandin C http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to arborcandin C (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001299 normal growth on pyrrolnitrin http://purl.obolibrary.org/obo/PHIPO_0001308 normal growth on chemical A growth phenotype which describes the absence of change of individuals or populations after exposure to pyrrolnitrin (i.e. indistinguishable from wild type). http://purl.obolibrary.org/obo/PHIPO_0001300 sensitive to pyrrolnitrin http://purl.obolibrary.org/obo/PHIPO_0000021 increased sensitivity to chemical A growth phenotype which describes the sensitivity of individuals or populations after exposure to pyrrolnitrin. Typically, organisms are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001301 resistance to pyrrolnitrin http://purl.obolibrary.org/obo/PHIPO_0000022 increased resistance to chemical A growth phenotype which describes the resistance of individuals or populations after exposure to pyrrolnitrin. Typically, organisms are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type individuals or populations to grow. http://purl.obolibrary.org/obo/PHIPO_0001302 resistance to osmotic stress http://purl.obolibrary.org/obo/PHIPO_0001096 resistance to stress A growth phenotype which describes the resistance of individuals or populations after exposure to an osmotic stress. Typically, individuals or populations are deemed resistant to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die). http://purl.obolibrary.org/obo/PHIPO_0001303 sensitive to osmotic stress http://purl.obolibrary.org/obo/PHIPO_0001098 sensitive to stress A growth phenotype which describes the sensitivity of individuals or populations after exposure to an osmotic stress. Typically, individuals or populations are deemed sensitive to a stress if they stop growing (and may die) when exposed to the stress at an intensity that allows an individual or population of wild type cell(s) to grow and divide. http://purl.obolibrary.org/obo/CL_4310083 GPin-BF cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0008061 GABA-Chol neuron A GABA-Chol neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPin-BF Cholinergic GABA. http://purl.obolibrary.org/obo/CL_4310084 striatal LAMP5 CXCL14 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023011 lamp5 GABAergic interneuron A lamp5 GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-CXCL14 GABA. http://purl.obolibrary.org/obo/CL_4310085 striatal LAMP5 LHX6 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042013 Lamp5 Lhx6 neuron A Lamp5 Lhx6 neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:LAMP5-LHX6 GABA. http://purl.obolibrary.org/obo/CL_4310088 BF SKOR1 Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_4042040 glutamatergic neuron of the basal ganglia A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:BF SKOR1 Glut. http://purl.obolibrary.org/obo/CL_4310093 arkypallidal neuron (Primate) http://purl.obolibrary.org/obo/CL_0020010 arkypallidal neuron A arkypallidal neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe MEIS2-SOX6 GABA. http://purl.obolibrary.org/obo/CL_4310094 prototypic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020009 prototypic neuron A prototypic neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe SOX6-CTXND1 GABA. http://purl.obolibrary.org/obo/CL_4310095 GPi Core neuron (Primate) http://purl.obolibrary.org/obo/CL_0020003 internal globus pallidus core projecting neuron A internal globus pallidus core projecting neuron of the Primates brain. These cells are located in the internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Core. http://purl.obolibrary.org/obo/CL_4310096 GPi Shell neuron (Primate) http://purl.obolibrary.org/obo/CL_0020004 internal globus pallidus shell projection neuron A internal globus pallidus shell projection neuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus, internal segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPi Shell. http://purl.obolibrary.org/obo/CL_4310100 GPe-NDB-SI LHX6-LHX8-GBX1 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, external segment of globus pallidus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:GPe-NDB-SI LHX6-LHX8-GBX1 GABA. http://purl.obolibrary.org/obo/CL_4310104 Islands of Calleja granule cell (Primate) http://purl.obolibrary.org/obo/CL_4030053 Islands of Calleja granule cell A Island of Calleja granule cell of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OT D1 ICj. http://purl.obolibrary.org/obo/CL_4310109 SN-VTR CALB1 Dopa substantia nigra dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000000 cell A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR CALB1 Dopa. http://purl.obolibrary.org/obo/CL_4310110 SN EBF2 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN EBF2 GABA. http://purl.obolibrary.org/obo/CL_4310111 SN-VTR GAD2 Dopa dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000000 cell A dopaminergic neuron of the Primates brain. These cells are located in the striatum, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR GAD2 Dopa. http://purl.obolibrary.org/obo/CL_4310112 SN GATA3-PAX8 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PAX8 GABA. http://purl.obolibrary.org/obo/CL_4310113 SN GATA3-PVALB GABA GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000000 cell A GABAergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN GATA3-PVALB GABA. http://purl.obolibrary.org/obo/CL_4310114 SN SEMA5A GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SEMA5A GABA. http://purl.obolibrary.org/obo/CL_4310115 SN SOX6 Dopa substantia nigra dopaminergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000000 cell A substantia nigra dopaminergic neuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN SOX6 Dopa. http://purl.obolibrary.org/obo/CL_4310117 SN-VTR-HTH GATA3-TCF7L2 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:SN-VTR-HTH GATA3-TCF7L2 GABA. http://purl.obolibrary.org/obo/CL_4310118 STH PVALB-PITX2 Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_4042040 glutamatergic neuron of the basal ganglia A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the subthalamic nucleus . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STH PVALB-PITX2 Glut. http://purl.obolibrary.org/obo/CL_4310120 striatal pthlh-expressing interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042023 striatal pthlh-expressing interneuron A striatal pthlh-expressing interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR FS PTHLH-PVALB GABA. http://purl.obolibrary.org/obo/CL_4310121 striatal SST-LYPD6-RSPO2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR LYPD6-RSPO2 GABA. http://purl.obolibrary.org/obo/CL_4310122 striatal SST-ADARB2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-ADARB2 GABA. http://purl.obolibrary.org/obo/CL_4310123 striatal SST-CHODL GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023121 sst chodl GABAergic interneuron A sst chodl GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-CHODL GABA. http://purl.obolibrary.org/obo/CL_4310124 striatal SST-RSPO2 GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023017 sst GABAergic interneuron A sst GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR SST-RSPO2 GABA. http://purl.obolibrary.org/obo/CL_4310125 STR TAC3-PLPP4 GABA TAC3-positive striatal interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR TAC3-PLPP4 GABA. http://purl.obolibrary.org/obo/CL_4310126 STR-BF TAC3-PLPP4-LHX8 GABA TAC3-positive striatal interneuron (Primate) http://purl.obolibrary.org/obo/CL_4042001 TAC3-positive striatal interneuron A TAC3-positive striatal interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR-BF TAC3-PLPP4-LHX8 GABA. http://purl.obolibrary.org/obo/CL_4310127 striatal VIP GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_4023016 VIP GABAergic interneuron A VIP GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VIP GABA. http://purl.obolibrary.org/obo/CL_4310128 STRd cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020007 dorso-striatal cholinergic-GABAergic neuron A dorso-striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd Cholinergic GABA. http://purl.obolibrary.org/obo/CL_4310129 STRd D1 Matrix medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030043 matrix D1 medium spiny neuron A matrix D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Matrix MSN. http://purl.obolibrary.org/obo/CL_4310130 striosomal D1 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030048 striosomal D1 medium spiny neuron A striosomal D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D1 Striosome MSN. http://purl.obolibrary.org/obo/CL_4310131 STRd D1/D2-hybrid medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_0000000 cell A D1/D2-hybrid medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR D1D2 Hybrid MSN. http://purl.obolibrary.org/obo/CL_4310132 STRd D2 Matrix medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030047 matrix D2 medium spiny neuron A matrix D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Matrix MSN. http://purl.obolibrary.org/obo/CL_4310133 STRd D2 Striomat hybrid medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_0000000 cell A indirect pathway medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 StrioMat Hybrid MSN. http://purl.obolibrary.org/obo/CL_4310134 striosomal D2 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030049 striosomal D2 medium spiny neuron A striosomal D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRd D2 Striosome MSN. http://purl.obolibrary.org/obo/CL_4310135 STR cholinergic-GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0020008 striatal cholinergic-GABAergic neuron A striatal cholinergic-GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STR Cholinergic GABA. http://purl.obolibrary.org/obo/CL_4310136 STRv D1 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030051 nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D1 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 MSN. http://purl.obolibrary.org/obo/CL_4310137 STRv D1-NUDAP medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030054 D1-NUDAP medium spiny neuron A D1-NUDAP medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D1 NUDAP MSN. http://purl.obolibrary.org/obo/CL_4310138 STRv D2 medium spiny neuron (Primate) http://purl.obolibrary.org/obo/CL_4030052 nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron A nucleus accumbens shell and olfactory tubercle D2 medium spiny neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:STRv D2 MSN. http://purl.obolibrary.org/obo/CL_4310143 ZI-HTH GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:ZI-HTH GABA. http://purl.obolibrary.org/obo/CL_4310144 VTR-HTH Glut glutamatergic neuron of the basal ganglia (Primate) http://purl.obolibrary.org/obo/CL_4042040 glutamatergic neuron of the basal ganglia A glutamatergic neuron of the basal ganglia of the Primates brain. These cells are located in the striatum, subthalamic nucleus, substantia nigra . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:VTR-HTH Glut. http://purl.obolibrary.org/obo/CL_4310145 AMY-SLEA-BNST D1 GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST D1 GABA. http://purl.obolibrary.org/obo/CL_4310146 AMY-SLEA-BNST GABA GABAergic interneuron (Primate) http://purl.obolibrary.org/obo/CL_0011005 GABAergic interneuron A GABAergic interneuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:AMY-SLEA-BNST GABA. http://purl.obolibrary.org/obo/CL_4310147 OB Dopa-GABA neuron (Primate) http://purl.obolibrary.org/obo/CL_0020006 OB-Dopa-GABA A OB-Dopa-GABA of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB Dopa-GABA. http://purl.obolibrary.org/obo/CL_4310148 OB FRMD7 GABA GABAergic neuron (Primate) http://purl.obolibrary.org/obo/CL_0000000 cell A GABAergic neuron of the Primates brain. These cells are located in the striatum . Reference transcriptomic data for this type can be found in the dataset/taxonomy - HMBA Basal Ganglia Consensus Taxonomy in cell set Group:OB FRMD7 GABA. http://purl.obolibrary.org/obo/CHEBI_184381 bacitracin A zwitterion http://purl.obolibrary.org/obo/CHEBI_27369 zwitterion https://purl.brain-bican.org/ontology/mbao/MBA_567 Cerebrum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_1129 Interbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_512 Cerebellum https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_129 third ventricle http://purl.obolibrary.org/obo/UBERON_0002286 third ventricle https://purl.brain-bican.org/ontology/mbao/MBA_370 Medulla, motor related http://purl.obolibrary.org/obo/BFO_0000004 independent continuant https://purl.brain-bican.org/ontology/mbao/MBA_1117 Pons, behavioral state related http://purl.obolibrary.org/obo/BFO_0000004 independent continuant https://purl.brain-bican.org/ontology/mbao/MBA_1132 Pons, sensory related http://purl.obolibrary.org/obo/BFO_0000004 independent continuant https://purl.brain-bican.org/ontology/mbao/MBA_856 Thalamus, polymodal association cortex related http://purl.obolibrary.org/obo/BFO_0000004 independent continuant http://purl.obolibrary.org/obo/CHEBI_135928 doripenem http://purl.obolibrary.org/obo/CHEBI_46633 carbapenems https://purl.brain-bican.org/ontology/mbao/MBA_304325711 retina http://purl.obolibrary.org/obo/UBERON_0000966 retina http://purl.obolibrary.org/obo/UBERON_0035767 intrapulmonary bronchus http://purl.obolibrary.org/obo/UBERON_0002185 bronchus https://purl.brain-bican.org/ontology/mbao/MBA_343 Brain stem https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/CHEBI_144644 a tetracycline zwitterion http://purl.obolibrary.org/obo/CHEBI_26895 tetracyclines http://purl.obolibrary.org/obo/CHEBI_192979 nystatin A2 http://purl.obolibrary.org/obo/CHEBI_59676 nystatins http://purl.obolibrary.org/obo/NCBITaxon_9443 Primates http://purl.obolibrary.org/obo/NCBITaxon_314146 Euarchontoglires http://purl.obolibrary.org/obo/UBERON_0036553 wall of synovial tendon sheath http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0036658 wall of central canal of spinal cord http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0005358 ventricle of nervous system http://purl.obolibrary.org/obo/UBERON_0036925 wall of eyeball http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0035965 wall of blood vessel http://purl.obolibrary.org/obo/UBERON_0000060 anatomical wall http://purl.obolibrary.org/obo/UBERON_0034944 zone of organ http://purl.obolibrary.org/obo/UBERON_0000064 organ part http://purl.obolibrary.org/obo/UBERON_0036253 orifice of skull http://purl.obolibrary.org/obo/UBERON_0000161 orifice http://purl.obolibrary.org/obo/UBERON_0036351 wall of brachiocephalic artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0036352 wall of subclavian artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0036422 wall of pulmonary artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall http://purl.obolibrary.org/obo/UBERON_0037094 wall of common carotid artery http://purl.obolibrary.org/obo/UBERON_0000415 artery wall https://purl.brain-bican.org/ontology/mbao/MBA_771 Pons https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_481 Islands of Calleja http://purl.obolibrary.org/obo/UBERON_0001881 island of Calleja https://purl.brain-bican.org/ontology/mbao/MBA_313 Midbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_354 Medulla http://purl.obolibrary.org/obo/UBERON_0001896 medulla oblongata https://purl.brain-bican.org/ontology/mbao/MBA_549 Thalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_958 Epithalamus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_223 Arcuate hypothalamic nucleus http://purl.obolibrary.org/obo/UBERON_0006331 brainstem nucleus https://purl.brain-bican.org/ontology/mbao/MBA_1065 Hindbrain https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_238 Nucleus raphe pontis http://purl.obolibrary.org/obo/UBERON_0002047 pontine raphe nucleus https://purl.brain-bican.org/ontology/mbao/MBA_528 Cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0002129 cerebellar cortex https://purl.brain-bican.org/ontology/mbao/MBA_599626923 Subcommissural organ https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_147 Locus ceruleus https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_462 Superior salivatory nucleus http://purl.obolibrary.org/obo/UBERON_0002149 superior salivatory nucleus https://purl.brain-bican.org/ontology/mbao/MBA_10671 Median eminence https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_338 Subfornical organ https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions https://purl.brain-bican.org/ontology/mbao/MBA_157 Periventricular zone http://purl.obolibrary.org/obo/UBERON_0002271 periventricular zone of hypothalamus https://purl.brain-bican.org/ontology/mbao/MBA_145 fourth ventricle http://purl.obolibrary.org/obo/UBERON_0002422 fourth ventricle https://purl.brain-bican.org/ontology/mbao/MBA_1031 Globus pallidus, internal segment http://purl.obolibrary.org/obo/UBERON_0002477 medial globus pallidus http://purl.obolibrary.org/obo/UBERON_0035763 cavity of cardiac chamber http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity http://purl.obolibrary.org/obo/UBERON_0035809 serous cavity http://purl.obolibrary.org/obo/UBERON_0002553 anatomical cavity https://purl.brain-bican.org/ontology/mbao/MBA_8 Basic cell groups and regions http://purl.obolibrary.org/obo/UBERON_0002616 regional part of brain https://purl.brain-bican.org/ontology/mbao/MBA_773 Hypoglossal nucleus http://purl.obolibrary.org/obo/UBERON_0002871 hypoglossal nucleus https://purl.brain-bican.org/ontology/mbao/MBA_1143 Cerebellar cortex, granular layer http://purl.obolibrary.org/obo/UBERON_0002956 granular layer of cerebellar cortex https://purl.brain-bican.org/ontology/mbao/MBA_1144 Cerebellar cortex, molecular layer http://purl.obolibrary.org/obo/UBERON_0002974 molecular layer of cerebellar cortex https://purl.brain-bican.org/ontology/mbao/MBA_1145 Cerebellar cortex, Purkinje layer http://purl.obolibrary.org/obo/UBERON_0002979 Purkinje cell layer of cerebellar cortex http://purl.obolibrary.org/obo/UBERON_0036073 respiratory primordium mesenchyme http://purl.obolibrary.org/obo/UBERON_0003104 mesenchyme http://purl.obolibrary.org/obo/UBERON_0034969 epithelial layer of duct http://purl.obolibrary.org/obo/UBERON_0003914 epithelial tube http://purl.obolibrary.org/obo/UBERON_0035037 jaw epithelium http://purl.obolibrary.org/obo/UBERON_0003929 digestive tract epithelium http://purl.obolibrary.org/obo/UBERON_0036072 respiratory primordium epithelium http://purl.obolibrary.org/obo/UBERON_0015833 foregut epithelium http://purl.obolibrary.org/obo/UBERON_0036654 wall of lateral ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0036656 wall of third ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain http://purl.obolibrary.org/obo/UBERON_0036657 wall of fourth ventricle http://purl.obolibrary.org/obo/UBERON_0036661 wall of ventricular system of brain https://purl.brain-bican.org/ontology/mbao/MBA_623 Cerebral nuclei http://purl.obolibrary.org/obo/UBERON_8440012 cerebral nuclei http://purl.obolibrary.org/obo/PHIPO_0000961 obsolete cell morphology phenotype A single species phenotype that affects the morphology of a cell. http://purl.obolibrary.org/obo/PHIPO_0000965 obsolete loss of virulence of gain of pathogenicity mutant A phenotype where the degree to which a pathogen (species or strain) is able to cause infectious disease in another organism is abolished when observed in an interaction with a pathogen mutant which was previously engineered to gain pathogenicity. http://purl.obolibrary.org/obo/PHIPO_0001157 obsolete unaltered pathogen reactive oxygen species production within host A pathogen host interaction metabolic cellular process phenotype in which the formation of reactive oxygen species (any molecules or ions formed by the incomplete one-electron reduction of oxygen) by the pathogen is unaltered within the host.(GO:1903409) http://purl.obolibrary.org/obo/PHIPO_0001162 obsolete host reproductive phenotype induced by pathogen A pathogen host interaction phenotype which affects the host reproductive process within the host when a pathogen is present. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). http://purl.obolibrary.org/obo/PHIPO_0001163 obsolete pathogen host interaction reproductive phenotype A pathogen host interaction phenotype which affects either the pathogen or host reproductive process. The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms (GO:0000003). http://purl.obolibrary.org/obo/PHIPO_0001164 obsolete abnormal host reproductive structure development induced by pathogen A host reproductive phenotype with pathogen where the process of host reproductive development is abnormal (GO:0048608). http://purl.obolibrary.org/obo/PHIPO_0001183 obsolete host resistance to pathogen phenotype A phenotype that is relevant to host resistance to a given pathogen. http://purl.obolibrary.org/obo/PHIPO_0001184 obsolete loss of functional host resistance gene A phenotype where the ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene is abolished (resistance was present and is now absent). http://purl.obolibrary.org/obo/PHIPO_0001185 obsolete gain of functional host resistance gene A phenotype where the ability of a host, to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene is acquired (resistance was absent and is now present). http://purl.obolibrary.org/obo/PHIPO_0001186 obsolete functional host resistance gene present A phenotype where ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene, is present. http://purl.obolibrary.org/obo/PHIPO_0001187 obsolete functional host resistance gene absent A phenotype where ability of a host to be resistant to a pathogen, via the recognition of a pathogen effector by a specific host resistance gene, is absent. http://purl.obolibrary.org/obo/PHIPO_0001188 obsolete gene-for-gene interaction phenotype A pathogen host interaction phenotype that affects the outcome of a gene-for-gene relationship in plant pathogen interactions. The gene-for-gene hypothesis follows that for each gene controlling resistance (R) in the host there is a corresponding gene controlling avirulence (avr) in the pathogen. http://purl.obolibrary.org/obo/PHIPO_0001189 obsolete compatible interaction A pathogen host interaction phenotype where the gene-for-gene relationship between the pathogen and plant host results in disease susceptibility. http://purl.obolibrary.org/obo/PHIPO_0001190 obsolete incompatible interaction A pathogen host interaction phenotype where the gene-for-gene relationship between the pathogen and plant host results in disease resistance. http://identifiers.org/ensembl/ENSG00000100604 CHGA http://identifiers.org/ensembl/ENSG00000107796 ACTA2 http://identifiers.org/ensembl/ENSG00000114805 PLCH1 http://identifiers.org/ensembl/ENSG00000122585 NPY http://identifiers.org/ensembl/ENSG00000125869 LAMP5 http://identifiers.org/ensembl/ENSG00000134443 GRP http://identifiers.org/ensembl/ENSG00000146469 VIP http://identifiers.org/ensembl/ENSG00000149591 TAGLN http://identifiers.org/ensembl/ENSG00000154080 CHST9 http://identifiers.org/ensembl/ENSG00000157005 SST http://identifiers.org/ensembl/ENSG00000157404 KIT http://identifiers.org/ensembl/ENSG00000235665 LINC00298 http://purl.obolibrary.org/obo/PHIPO_0000950 obsolete pathogen spore germination on host phenotype http://purl.obolibrary.org/obo/RO_0004009 has primary input http://purl.obolibrary.org/obo/RO_0002233 has input p has primary input c if (a) p has input c and (b) the goal of process is to modify, consume, or transform c. http://purl.obolibrary.org/obo/RO_0002025 has effector activity http://purl.obolibrary.org/obo/RO_0002017 has component activity A 'has effector activity' B if A and B are GO molecular functions (GO_0003674), A 'has component activity' B and B is the effector (output function) of B. Each compound function has only one effector activity. http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure http://purl.obolibrary.org/obo/RO_0000057 has participant p has anatomical participant c iff p has participant c, and c is an anatomical entity http://purl.obolibrary.org/obo/RO_0002100 has soma location http://purl.obolibrary.org/obo/RO_0002131 overlaps Relation between a neuron and a material anatomical entity that its soma is part of. http://purl.obolibrary.org/obo/RO_0002160 only in taxon http://purl.obolibrary.org/obo/RO_0002162 in taxon x only in taxon y if and only if x is in taxon y, and there is no other organism z such that y!=z a and x is in taxon z. http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by http://purl.obolibrary.org/obo/RO_0002324 developmentally related to Candidate definition: x developmentally related to y if and only if there exists some developmental process (GO:0032502) p such that x and y both participates in p, and x is the output of p and y is the input of p http://purl.obolibrary.org/obo/RO_0002234 has output http://purl.obolibrary.org/obo/RO_0000057 has participant p has output c iff c is a participant in p, c is present at the end of p, and c is not present in the same state at the beginning of p. http://purl.obolibrary.org/obo/RO_0002162 in taxon http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to x is in taxon y if an only if y is an organism, and the relationship between x and y is one of: part of (reflexive), developmentally preceded by, derives from, secreted by, expressed. http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving Inverse of developmentally preceded by http://purl.obolibrary.org/obo/RO_0002371 attached to http://purl.obolibrary.org/obo/RO_0002177 attached to part of a is attached to b if and only if a and b are discrete objects or object parts, and there are physical connections between a and b such that a force pulling a will move b, or a force pulling b will move a http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving http://purl.obolibrary.org/obo/RO_0002324 developmentally related to x has developmental potential involving y iff x is capable of a developmental process with output y. y may be the successor of x, or may be a different structure in the vicinity (as for example in the case of developmental induction). http://purl.obolibrary.org/obo/RO_0002388 has potential to directly develop into http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into x has potential to directly develop into y iff x directly develops into y or x is capable of directly developing into y http://purl.obolibrary.org/obo/RO_0002178 supplies http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an arterial structure and another structure, where the arterial structure acts as a conduit channeling fluid, substance or energy. http://purl.obolibrary.org/obo/RO_0002372 has muscle origin http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_origin s iff m is attached_to s, and it is the case that when m contracts, s does not move. The site of the origin tends to be more proximal and have greater mass than what the other end attaches to. http://purl.obolibrary.org/obo/RO_0002380 branching part of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x is a branching part of y if and only if x is part of y and x is connected directly or indirectly to the main stem of y http://purl.obolibrary.org/obo/RO_0002569 has branching part http://purl.obolibrary.org/obo/BFO_0000051 has_part inverse of branching part of http://purl.obolibrary.org/obo/RO_0002571 lumen of http://purl.obolibrary.org/obo/BFO_0000050 part_of x lumen_of y iff x is the space or substance that is part of y and does not cross any of the inner membranes or boundaries of y that is maximal with respect to the volume of the convex hull. http://purl.obolibrary.org/obo/uberon/core#anteriorly_connected_to anteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x anteriorly_connected_to y iff the anterior part of x is connected to y. i.e. x connected_to y and x posterior_to y. http://purl.obolibrary.org/obo/uberon/core#distally_connected_to distally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x distally_connected_to y iff the distal part of x is connected to y. i.e. x connected_to y and x proximal_to y. http://purl.obolibrary.org/obo/uberon/core#posteriorly_connected_to posteriorly connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x posteriorly_connected_to y iff the posterior part of x is connected to y. i.e. x connected_to y and x anterior_to y. http://purl.obolibrary.org/obo/uberon/core#proximally_connected_to proximally connected to http://purl.obolibrary.org/obo/RO_0002170 connected to x proximally_connected_to y iff the proximal part of x is connected to y. i.e. x connected_to y and x distal_to y. http://purl.obolibrary.org/obo/RO_0004007 has primary input or output http://purl.obolibrary.org/obo/RO_0000057 has participant p 'has primary input ot output' c iff either (a) p 'has primary input' c or (b) p 'has primary output' c. http://purl.obolibrary.org/obo/RO_0004008 has primary output http://purl.obolibrary.org/obo/RO_0004007 has primary input or output p has primary output c if (a) p has output c and (b) the goal of process is to modify, produce, or transform c. http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/RO_0002222 temporally related to x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0000052 characteristic of http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of a relation between a specifically dependent continuant (the characteristic) and any other entity (the bearer), in which the characteristic depends on the bearer for its existence. http://purl.obolibrary.org/obo/RO_0000079 function of http://purl.obolibrary.org/obo/RO_0000052 characteristic of a relation between a function and an independent continuant (the bearer), in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000080 quality of http://purl.obolibrary.org/obo/RO_0000052 characteristic of a relation between a quality and an independent continuant (the bearer), in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000085 has function http://purl.obolibrary.org/obo/RO_0000053 has characteristic a relation between an independent continuant (the bearer) and a function, in which the function specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000086 has quality http://purl.obolibrary.org/obo/RO_0000053 has characteristic a relation between an independent continuant (the bearer) and a quality, in which the quality specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002000 2D boundary of http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a 2D immaterial entity (the boundary) and a material entity, in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0002002 has 2D boundary http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a relation between a material entity and a 2D immaterial entity (the boundary), in which the boundary delimits the material entity http://purl.obolibrary.org/obo/RO_0002219 surrounded by http://purl.obolibrary.org/obo/RO_0002220 adjacent to x surrounded_by y if and only if (1) x is adjacent to y and for every region r that is adjacent to x, r overlaps y (2) the shared boundary between x and y occupies the majority of the outermost boundary of x http://purl.obolibrary.org/obo/RO_0002220 adjacent to http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from x adjacent to y if and only if x and y share a boundary. http://purl.obolibrary.org/obo/RO_0002223 starts http://purl.obolibrary.org/obo/BFO_0000050 part_of inverse of starts with http://purl.obolibrary.org/obo/RO_0002350 member of http://purl.obolibrary.org/obo/BFO_0000050 part_of is member of is a mereological relation between a item and a collection. http://purl.obolibrary.org/obo/RO_0002351 has member http://purl.obolibrary.org/obo/BFO_0000051 has_part has member is a mereological relation between a collection and an item. http://purl.obolibrary.org/obo/RO_0002018 has component process http://purl.obolibrary.org/obo/RO_0002180 has component w 'has process component' p if p and w are processes, w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/RO_0019000 regulates characteristic http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a process and a characteristic in which process (P) regulates characteristic (C) iff: P results in the existence of C OR affects the intensity or magnitude of C. http://purl.obolibrary.org/obo/RO_0019001 positively regulates characteristic http://purl.obolibrary.org/obo/RO_0019000 regulates characteristic A relationship that holds between a process and a characteristic in which process (P) positively regulates characteristic (C) iff: P results in an increase in the intensity or magnitude of C. http://purl.obolibrary.org/obo/RO_0019002 negatively regulates characteristic http://purl.obolibrary.org/obo/RO_0019000 regulates characteristic A relationship that holds between a process and a characteristic in which process (P) negatively regulates characteristic (C) iff: P results in a decrease in the intensity or magnitude of C. http://purl.obolibrary.org/obo/RO_0002202 develops from http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from x develops from y if and only if either (a) x directly develops from y or (b) there exists some z such that x directly develops from z and z develops from y http://purl.obolibrary.org/obo/BFO_0000051 has_part http://purl.obolibrary.org/obo/RO_0002131 overlaps a core relation that holds between a whole and its part http://purl.obolibrary.org/obo/RO_0000087 has role http://purl.obolibrary.org/obo/RO_0000053 has characteristic a relation between an independent continuant (the bearer) and a role, in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002176 connects http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to c connects a if and only if there exist some b such that a and b are similar parts of the same system, and c connects b, specifically, c connects a with b. When one structure connects two others it unites some aspect of the function or role they play within the system. http://purl.obolibrary.org/obo/RO_0002491 existence starts and ends during http://purl.obolibrary.org/obo/RO_0002492 existence ends during x exists during y if and only if: 1) the time point at which x begins to exist is after or equal to the time point at which y begins and 2) the time point at which x ceases to exist is before or equal to the point at which y ends. Formally: x existence starts and ends during y iff α(x) >= α(y) & α(x) <= ω(y) & ω(x) <= ω(y) & ω(x) >= α(y) http://purl.obolibrary.org/obo/RO_0002327 enables http://purl.obolibrary.org/obo/RO_0002215 capable of c enables p iff c is capable of p and c acts to execute p. http://purl.obolibrary.org/obo/RO_0002333 enabled by http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of enables http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of upstream of http://purl.obolibrary.org/obo/RO_0002409 indirectly negatively regulates http://purl.obolibrary.org/obo/RO_0002212 negatively regulates p indirectly negatively regulates q iff p is indirectly causally upstream of q and p negatively regulates q. http://purl.obolibrary.org/obo/RO_0002412 immediately causally upstream of http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p is immediately causally upstream of q iff p is causally upstream of q, and the end of p is coincident with the beginning of q. http://purl.obolibrary.org/obo/RO_0002436 molecularly interacts with http://purl.obolibrary.org/obo/RO_0002434 interacts with An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other. http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of http://purl.obolibrary.org/obo/RO_0011002 regulates activity of The entity A, immediately upstream of the entity B, has an activity that regulates an activity performed by B. For example, A and B may be gene products and binding of B by A regulates the kinase activity of B. A and B can be physically interacting but not necessarily. Immediately upstream means there are no intermediate entity between A and B. http://purl.obolibrary.org/obo/RO_0002449 directly negatively regulates activity of http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of The entity A, immediately upstream of the entity B, has an activity that negatively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B. http://purl.obolibrary.org/obo/RO_0002566 causally influences http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities The entity or characteristic A is causally upstream of the entity or characteristic B, A having an effect on B. An entity corresponds to any biological type of entity as long as a mass is measurable. A characteristic corresponds to a particular specificity of an entity (e.g., phenotype, shape, size). http://purl.obolibrary.org/obo/RO_0002490 existence overlaps http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence overlaps y if and only if either (a) the start of x is part of y or (b) the end of x is part of y. Formally: x existence starts and ends during y iff (α(x) >= α(y) & α(x) <= ω(y)) OR (ω(x) <= ω(y) & ω(x) >= α(y)) http://purl.obolibrary.org/obo/RO_0002252 connecting branch of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with b connecting-branch-of s iff b is connected to s, and there exists some tree-like structure t such that the mereological sum of b plus s is either the same as t or a branching-part-of t. http://purl.obolibrary.org/obo/RO_0002253 has connecting branch http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with inverse of connecting branch of http://purl.obolibrary.org/obo/RO_0002263 acts upstream of http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes. http://purl.obolibrary.org/obo/RO_0002304 causally upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect p is causally upstream of, positive effect q iff p is casually upstream of q, and the execution of p is required for the execution of q. http://purl.obolibrary.org/obo/RO_0002305 causally upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect p is causally upstream of, negative effect q iff p is casually upstream of q, and the execution of p decreases the execution of q. http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to x overlaps y if and only if there exists some z such that x has part z and z part of y http://purl.obolibrary.org/obo/RO_0002150 continuous with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to X continuous_with Y if and only if X and Y share a fiat boundary. http://purl.obolibrary.org/obo/RO_0002254 has developmental contribution from http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x has developmental contribution from y iff x has some part z such that z develops from y http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence starts during or after y if and only if the time point at which x starts is after or equivalent to the time point at which y starts. Formally: x existence starts during or after y iff α (x) >= α (y). http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage x existence ends during or before y if and only if the time point at which x ends is before or equivalent to the time point at which y ends. http://purl.obolibrary.org/obo/RO_0000091 has disposition http://purl.obolibrary.org/obo/RO_0000053 has characteristic a relation between an independent continuant (the bearer) and a disposition, in which the disposition specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0000092 disposition of http://purl.obolibrary.org/obo/RO_0000052 characteristic of inverse of has disposition http://purl.obolibrary.org/obo/RO_0011002 regulates activity of http://purl.obolibrary.org/obo/RO_0002566 causally influences The entity A has an activity that regulates an activity of the entity B. For example, A and B are gene products where the catalytic activity of A regulates the kinase activity of B. http://purl.obolibrary.org/obo/RO_0012003 acts on population of http://purl.obolibrary.org/obo/RO_0000057 has participant p acts on population of c iff c' is a collection, has members of type c, and p has participant c http://purl.obolibrary.org/obo/BFO_0000062 preceded by http://purl.obolibrary.org/obo/RO_0002086 ends after x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0000081 role of http://purl.obolibrary.org/obo/RO_0000052 characteristic of a relation between a role and an independent continuant (the bearer), in which the role specifically depends on the bearer for its existence http://purl.obolibrary.org/obo/RO_0002411 causally upstream of http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within p is causally upstream of q iff p is causally related to q, the end of p precedes the end of q, and p is not an occurrent part of q. http://purl.obolibrary.org/obo/BFO_0000050 part_of http://purl.obolibrary.org/obo/RO_0002131 overlaps a core relation that holds between a part and its whole http://purl.obolibrary.org/obo/RO_0002211 regulates http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p regulates q iff p is causally upstream of q, the execution of p is not constant and varies according to specific conditions, and p influences the rate or magnitude of execution of q due to an effect either on some enabler of q or some enabler of a part of q. http://purl.obolibrary.org/obo/RO_0002212 negatively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates p negatively regulates q iff p regulates q, and p decreases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/RO_0002213 positively regulates http://purl.obolibrary.org/obo/RO_0002211 regulates p positively regulates q iff p regulates q, and p increases the rate or magnitude of execution of q. http://purl.obolibrary.org/obo/RO_0002180 has component http://purl.obolibrary.org/obo/BFO_0000051 has_part w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type. http://purl.obolibrary.org/obo/RO_0002163 spatially disjoint from http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A is spatially_disjoint_from B if and only if they have no parts in common http://purl.obolibrary.org/obo/RO_0002233 has input http://purl.obolibrary.org/obo/RO_0000057 has participant p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p. http://purl.obolibrary.org/obo/RO_0002314 characteristic of part of http://purl.obolibrary.org/obo/RO_0002502 depends on q characteristic of part of w if and only if there exists some p such that q inheres in p and p part of w. http://purl.obolibrary.org/obo/RO_0002352 input of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has input http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/RO_0002328 functionally related to inverse of has output http://purl.obolibrary.org/obo/RO_0002473 composed primarily of http://purl.obolibrary.org/obo/BFO_0000051 has_part x composed_primarily_of y if and only if more than half of the mass of x is made from y or units of the same type as y. http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part http://purl.obolibrary.org/obo/BFO_0000051 has_part Holds between a cell c and a protein complex or protein p if and only if that cell has as part a plasma_membrane[GO:0005886], and that plasma membrane has p as part. http://purl.obolibrary.org/obo/RO_0002203 develops into http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by inverse of develops from http://purl.obolibrary.org/obo/RO_0002215 capable of http://purl.obolibrary.org/obo/RO_0002216 capable of part of A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. http://purl.obolibrary.org/obo/RO_0002387 has potential to develop into http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has the potential to develop into y iff x develops into y or if x is capable of developing into y http://purl.obolibrary.org/obo/RO_0002021 occurs across http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in A relationship between a process and a barrier, where the process occurs in a region spanning the barrier. For cellular processes the barrier is typically a membrane. Examples include transport across a membrane and membrane depolarization. http://purl.obolibrary.org/obo/RO_0002023 directly negatively regulated by http://purl.obolibrary.org/obo/RO_0002022 directly regulated by Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1. http://purl.obolibrary.org/obo/RO_0002024 directly positively regulated by http://purl.obolibrary.org/obo/RO_0002022 directly regulated by Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2). For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1. http://purl.obolibrary.org/obo/RO_0015007 increased in magnitude relative to http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/RO_0002090 immediately precedes http://purl.obolibrary.org/obo/BFO_0000063 precedes http://purl.obolibrary.org/obo/GOREL_0002004 results in fission of http://purl.obolibrary.org/obo/RO_0000057 has participant http://purl.obolibrary.org/obo/RO_0002563 interaction relation helper property http://purl.obolibrary.org/obo/RO_0002464 helper property (not for use in curation) http://purl.obolibrary.org/obo/RO_0002564 molecular interaction relation helper property http://purl.obolibrary.org/obo/RO_0002563 interaction relation helper property http://purl.obolibrary.org/obo/RO_0002481 is kinase activity http://purl.obolibrary.org/obo/RO_0002564 molecular interaction relation helper property http://purl.obolibrary.org/obo/RO_0002087 immediately preceded by http://purl.obolibrary.org/obo/BFO_0000062 preceded by http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002086 ends after http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/RO_0002092 happens during http://purl.obolibrary.org/obo/RO_0002093 ends during http://purl.obolibrary.org/obo/RO_0004033 acts upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002022 directly regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities http://purl.obolibrary.org/obo/RO_0002410 causally related to http://purl.obolibrary.org/obo/uberon/core#filtered_through filtered through Relationship between a fluid and a material entity, where the fluid is the output of a realization of a filtration role that inheres in the material entity. http://purl.obolibrary.org/obo/pato#decreased_in_magnitude_relative_to obsolete decreased_in_magnitude_relative_to OBSOLETE. q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/pato#increased_in_magnitude_relative_to obsolete increased_in_magnitude_relative_to OBSOLETE. q1 increased_in_magnitude_relative_to q2 if and only if magnitude(q1) > magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/RO_0002320 evolutionarily related to A relationship that holds via some environmental process http://purl.obolibrary.org/obo/RO_0002324 developmentally related to A relationship that holds between entities participating in some developmental process (GO:0032502) http://purl.obolibrary.org/obo/uberon/core#site_of site_of c site_of p if c is the bearer of a disposition that is realized by a process that has p as part. http://purl.obolibrary.org/obo/RO_0015004 has characterizing marker set A relation that applies between a cell type and a set of markers that can be used to uniquely identify that cell type. http://purl.obolibrary.org/obo/BFO_0000067 contains process [copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0000053 has characteristic Inverse of characteristic_of http://purl.obolibrary.org/obo/RO_0000056 participates in a relation between a continuant and a process, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0000057 has participant a relation between a process and a continuant, in which the continuant is somehow involved in the process http://purl.obolibrary.org/obo/RO_0001015 location of a relation between two independent continuants, the location and the target, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0017001 device utilizes material X device utilizes material Y means X and Y are material entities, and X is capable of some process P that has input Y. http://purl.obolibrary.org/obo/RO_0001025 located in a relation between two independent continuants, the target and the location, in which the target is entirely within the location http://purl.obolibrary.org/obo/RO_0003000 produces a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix. http://purl.obolibrary.org/obo/RO_0003001 produced by a produced_by b iff some process that occurs_in b has_output a. http://purl.obolibrary.org/obo/RO_0015001 has exemplar data A relation between a material entity and some data in which the data is taken as exemplifying the material entity. http://purl.obolibrary.org/obo/RO_0002434 interacts with A relationship that holds between two entities in which the processes executed by the two entities are causally connected. http://purl.obolibrary.org/obo/RO_0002573 has modifier A relation that holds between an attribute or a qualifier and another attribute. http://purl.obolibrary.org/obo/so#has_part has_part Inverse of part_of. http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 different_in_magnitude_relative_to q2 if and only if magnitude(q1) NOT =~ magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/BFO_0000066 occurs in b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A mereological relationship or a topological relationship http://purl.obolibrary.org/obo/RO_0002328 functionally related to A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities. http://purl.obolibrary.org/obo/RO_0015011 has cross section s3 has_cross_section s3 if and only if : there exists some 2d plane that intersects the bearer of s3, and the impression of s3 upon that plane has shape quality s2. http://purl.obolibrary.org/obo/RO_0015012 reciprocal of q1 reciprocal_of q2 if and only if : q1 and q2 are relational qualities and a phenotype e q1 e2 mutually implies a phenotype e2 q2 e. http://purl.obolibrary.org/obo/RO_0020104 is neuron This property only applies to neurons http://purl.obolibrary.org/obo/RO_0020105 is anatomical entity This property only applies to anatomical entities. http://purl.obolibrary.org/obo/pato#has_relative_magnitude obsolete has_relative_magnitude http://purl.obolibrary.org/obo/pato#towards obsolete towards http://purl.obolibrary.org/obo/uberon/core#channels_from channels_from http://purl.obolibrary.org/obo/uberon/core#channels_into channels_into http://purl.obolibrary.org/obo/uberon/core#transitively_anteriorly_connected_to transitively anteriorly connected to http://purl.obolibrary.org/obo/uberon/core#transitively_distally_connected_to transitively distally connected to http://purl.obolibrary.org/obo/uberon/core#transitively_proximally_connected_to transitively proximally connected to http://purl.obolibrary.org/obo/BFO_0000054 realized in http://purl.obolibrary.org/obo/BFO_0000055 realizes http://purl.obolibrary.org/obo/RO_0002464 helper property (not for use in curation) http://purl.obolibrary.org/obo/RO_0002487 relation between physical entity and a process or stage http://purl.obolibrary.org/obo/PHIPO_0000304 qualifier http://purl.obolibrary.org/obo/CL_4030045 lacks_part http://purl.obolibrary.org/obo/RO_0002222 temporally related to http://purl.obolibrary.org/obo/CL_4030046 lacks_plasma_membrane_part http://purl.obolibrary.org/obo/RO_0002093 ends during http://purl.obolibrary.org/obo/RO_0002502 depends on http://purl.obolibrary.org/obo/RO_0015010 has relative magnitude http://purl.obolibrary.org/obo/RO_0015008 decreased in magnitude relative to http://purl.obolibrary.org/obo/RO_0015006 different in magnitude relative to q1 decreased_in_magnitude_relative_to q2 if and only if magnitude(q1) < magnitude(q2). Here, magnitude(q) is a function that maps a quality to a unit-invariant scale. http://purl.obolibrary.org/obo/RO_0012011 indirectly causally upstream of http://purl.obolibrary.org/obo/RO_0002411 causally upstream of p is indirectly causally upstream of q iff p is causally upstream of q and there exists some process r such that p is causally upstream of r and r is causally upstream of q. http://purl.obolibrary.org/obo/RO_0012012 indirectly regulates http://purl.obolibrary.org/obo/RO_0012011 indirectly causally upstream of p indirectly regulates q iff p is indirectly causally upstream of q and p regulates q. http://purl.obolibrary.org/obo/RO_0002007 bounding layer of http://purl.obolibrary.org/obo/BFO_0000050 part_of X outer_layer_of Y iff: . X :continuant that bearer_of some PATO:laminar . X part_of Y . exists Z :surface . X has_boundary Z . Z boundary_of Y has_boundary: http://purl.obolibrary.org/obo/RO_0002002 boundary_of: http://purl.obolibrary.org/obo/RO_0002000 http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to a is connected to b if and only if a and b are discrete structure, and there exists some connecting structure c, such that c connects a and b http://purl.obolibrary.org/obo/RO_0002177 attached to part of http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to a is attached to part of b if a is attached to b, or a is attached to some p, where p is part of b. http://purl.obolibrary.org/obo/RO_0002179 drains http://purl.obolibrary.org/obo/RO_0002170 connected to Relation between an collecting structure and another structure, where the collecting structure acts as a conduit channeling fluid, substance or energy away from the other structure. http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process. http://purl.obolibrary.org/obo/RO_0002331 involved in http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of c involved_in p if and only if c enables some process p', and p' is part of p http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with http://purl.obolibrary.org/obo/RO_0002323 mereotopologically related to A relationship that holds between two material entities in a system of connected structures, where the branching relationship holds based on properties of the connecting network. http://purl.obolibrary.org/obo/RO_0002376 tributary of http://purl.obolibrary.org/obo/RO_0002375 in branching relationship with x tributary_of y if and only if x a channel for the flow of a substance into y, where y is larger than x. If x and y are hydrographic features, then y is the main stem of a river, or a lake or bay, but not the sea or ocean. If x and y are anatomical, then y is a vein. http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p http://purl.obolibrary.org/obo/RO_0002503 towards http://purl.obolibrary.org/obo/RO_0002502 depends on q towards e2 if and only if q is a relational quality such that q inheres-in some e, and e != e2 and q is dependent on e2 http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to http://purl.obolibrary.org/obo/RO_0002328 functionally related to A relation that holds between elements of a musculoskeletal system or its analogs. http://purl.obolibrary.org/obo/RO_0002373 has muscle insertion http://purl.obolibrary.org/obo/RO_0002567 biomechanically related to m has_muscle_insertion s iff m is attaches_to s, and it is the case that when m contracts, s moves. Insertions are usually connections of muscle via tendon to bone. http://purl.obolibrary.org/obo/RO_0002433 contributes to morphology of http://purl.obolibrary.org/obo/RO_0002131 overlaps p contributes to morphology of w if and only if a change in the morphology of p entails a change in the morphology of w. Examples: every skull contributes to morphology of the head which it is a part of. Counter-example: nuclei do not generally contribute to the morphology of the cell they are part of, as they are buffered by cytoplasm. http://purl.obolibrary.org/obo/RO_0002488 existence starts during http://purl.obolibrary.org/obo/RO_0002496 existence starts during or after x existence starts during y if and only if the time point at which x starts is after or equivalent to the time point at which y starts and before or equivalent to the time point at which y ends. Formally: x existence starts during y iff α(x) >= α(y) & α(x) <= ω(y). http://purl.obolibrary.org/obo/RO_0002489 existence starts with http://purl.obolibrary.org/obo/RO_0002488 existence starts during x starts ends with y if and only if the time point at which x starts is equivalent to the time point at which y starts. Formally: x existence starts with y iff α(x) = α(y). http://purl.obolibrary.org/obo/RO_0002492 existence ends during http://purl.obolibrary.org/obo/RO_0002497 existence ends during or before x existence ends during y if and only if the time point at which x ends is before or equivalent to the time point at which y ends and after or equivalent to the point at which y starts. Formally: x existence ends during y iff ω(x) <= ω(y) and ω(x) >= α(y). http://purl.obolibrary.org/obo/RO_0002493 existence ends with http://purl.obolibrary.org/obo/RO_0002492 existence ends during x existence ends with y if and only if the time point at which x ends is equivalent to the time point at which y ends. Formally: x existence ends with y iff ω(x) = ω(y). http://purl.obolibrary.org/obo/RO_0002494 transformation of http://purl.obolibrary.org/obo/RO_0002202 develops from x transformation of y if x is the immediate transformation of y, or is linked to y through a chain of transformation relationships http://purl.obolibrary.org/obo/RO_0002495 immediate transformation of http://purl.obolibrary.org/obo/RO_0002207 directly develops from x immediate transformation of y iff x immediately succeeds y temporally at a time boundary t, and all of the matter present in x at t is present in y at t, and all the matter in y at t is present in x at t http://purl.obolibrary.org/obo/RO_0002551 has skeleton http://purl.obolibrary.org/obo/BFO_0000051 has_part A relation between a segment or subdivision of an organism and the maximal subdivision of material entities that provides structural support for that segment or subdivision. http://purl.obolibrary.org/obo/RO_0002572 luminal space of http://purl.obolibrary.org/obo/RO_0002571 lumen of s is luminal space of x iff s is lumen_of x and s is an immaterial entity http://purl.obolibrary.org/obo/RO_0002576 skeleton of http://purl.obolibrary.org/obo/BFO_0000050 part_of inverse of has skeleton http://purl.obolibrary.org/obo/uberon/core#extends_fibers_into extends_fibers_into http://purl.obolibrary.org/obo/RO_0002170 connected to X extends_fibers into Y iff there exists some neuron (N) and N has_soma_location X and N 'has synaptic IO in region' some Y http://purl.obolibrary.org/obo/RO_0004031 enables subfunction http://purl.obolibrary.org/obo/RO_0002328 functionally related to Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P. http://purl.obolibrary.org/obo/RO_0004034 acts upstream of, positive effect http://purl.obolibrary.org/obo/RO_0004032 acts upstream of or within, positive effect c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive http://purl.obolibrary.org/obo/RO_0004035 acts upstream of, negative effect http://purl.obolibrary.org/obo/RO_0004033 acts upstream of or within, negative effect c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative http://purl.obolibrary.org/obo/RO_0020101 vessel supplies blood to http://purl.obolibrary.org/obo/RO_0002178 supplies x vessel supplies blood to y if and only if x is a vessel that supplies blood directly or indirectly to an anatomical structure y. http://purl.obolibrary.org/obo/RO_0020102 vessel drains blood from http://purl.obolibrary.org/obo/RO_0002179 drains x vessel drains blood from y if and only if x is a vessel that drains blood directly or indirectly from an anatomical structure y. http://purl.obolibrary.org/obo/RO_0002103 synapsed by http://purl.obolibrary.org/obo/RO_0002485 receives input from Relation between an anatomical structure (including cells) and a neuron that chemically synapses to it. http://purl.obolibrary.org/obo/RO_0002110 has postsynaptic terminal in http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/RO_0002113 has presynaptic terminal in http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in Relation between a neuron and some structure (e.g.- a brain region) in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/RO_0002120 synapsed to http://purl.obolibrary.org/obo/RO_0002486 sends output to Relation between a neuron and an anatomical structure (including cells) that it chemically synapses to. http://purl.obolibrary.org/obo/RO_0002130 has synaptic terminal in http://purl.obolibrary.org/obo/RO_0002131 overlaps A general relation between a neuron and some structure in which it either chemically synapses to some target or in which it receives (chemical) synaptic input. http://purl.obolibrary.org/obo/RO_0002216 capable of part of http://purl.obolibrary.org/obo/RO_0002500 causal agent in process c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p. http://purl.obolibrary.org/obo/RO_0002255 developmentally contributes to http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to inverse of has developmental contribution from http://purl.obolibrary.org/obo/RO_0002329 part of structure that is capable of http://purl.obolibrary.org/obo/RO_0002328 functionally related to this relation holds between c and p when c is part of some c', and c' is capable of p. http://purl.obolibrary.org/obo/RO_0002334 regulated by http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within inverse of regulates http://purl.obolibrary.org/obo/RO_0002335 negatively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of negatively regulates http://purl.obolibrary.org/obo/RO_0002336 positively regulated by http://purl.obolibrary.org/obo/RO_0002334 regulated by inverse of positively regulates http://purl.obolibrary.org/obo/RO_0002379 spatially coextensive with http://purl.obolibrary.org/obo/RO_0002131 overlaps x spatially_coextensive_with y if and inly if x and y have the same location http://purl.obolibrary.org/obo/RO_0002385 has potential to developmentally contribute to http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentrally contribute to y iff x developmentally contributes to y or x is capable of developmentally contributing to y http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes p is 'causally upstream or within' q iff p is causally related to q, and the end of p precedes, or is coincident with, the end of q. http://purl.obolibrary.org/obo/RO_0002427 causally downstream of or within http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes inverse of causally upstream of or within http://purl.obolibrary.org/obo/RO_0002500 causal agent in process http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process A relationship between a material entity and a process where the material entity has some causal role that influences the process http://purl.obolibrary.org/obo/RO_0002501 causal relation between processes http://purl.obolibrary.org/obo/RO_0002410 causally related to p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one where the execution of p influences the execution of q. p may be upstream, downstream, part of, or a container of q. http://purl.obolibrary.org/obo/RO_0002584 has part structure that is capable of http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p http://purl.obolibrary.org/obo/RO_0002595 causal relation between material entity and a process http://purl.obolibrary.org/obo/RO_0002410 causally related to A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity. http://purl.obolibrary.org/obo/RO_0002596 capable of regulating http://purl.obolibrary.org/obo/RO_0002500 causal agent in process Holds between c and p if and only if c is capable of some activity a, and a regulates p. http://purl.obolibrary.org/obo/RO_0002597 capable of negatively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p. http://purl.obolibrary.org/obo/RO_0002598 capable of positively regulating http://purl.obolibrary.org/obo/RO_0002596 capable of regulating Holds between c and p if and only if c is capable of some activity a, and a positively regulates p. http://purl.obolibrary.org/obo/RO_0002608 process has causal agent http://purl.obolibrary.org/obo/RO_0002410 causally related to Inverse of 'causal agent in process' http://purl.obolibrary.org/obo/RO_0002015 has positive regulatory component activity http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B. http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity http://purl.obolibrary.org/obo/RO_0002017 has component activity A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B. http://purl.obolibrary.org/obo/RO_0002014 has negative regulatory component activity http://purl.obolibrary.org/obo/RO_0002013 has regulatory component activity A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole. More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B. http://purl.obolibrary.org/obo/RO_0002082 simultaneous with http://purl.obolibrary.org/obo/RO_0002081 before or simultaneous with x simultaneous with y iff ω(x) = ω(y) and ω(α ) = ω(α), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point and '=' indicates the same instance in time. http://purl.obolibrary.org/obo/RO_0002206 expressed in http://purl.obolibrary.org/obo/RO_0002330 genomically related to x expressed in y if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and the transcription of x is part of the gene expression process (iii) x is a mature gene product such as a protein, and x was translated or otherwise processes from a transcript that was transcribed as part of this gene expression process http://purl.obolibrary.org/obo/RO_0002207 directly develops from http://purl.obolibrary.org/obo/RO_0002202 develops from Candidate definition: x directly_develops from y if and only if there exists some developmental process (GO:0032502) p such that x and y both participate in p, and x is the output of p and y is the input of p, and a substantial portion of the matter of x comes from y, and the start of x is coincident with or after the end of y. http://purl.obolibrary.org/obo/RO_0002210 directly develops into http://purl.obolibrary.org/obo/RO_0002203 develops into inverse of directly develops from http://purl.obolibrary.org/obo/RO_0002221 surrounds http://purl.obolibrary.org/obo/RO_0002220 adjacent to inverse of surrounded by http://purl.obolibrary.org/obo/RO_0002224 starts with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x starts with y if and only if x has part y and the time point at which x starts is equivalent to the time point at which y starts. Formally: α(y) = α(x) ∧ ω(y) < ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002225 develops from part of http://purl.obolibrary.org/obo/RO_0002202 develops from x develops from part of y if and only if there exists some z such that x develops from z and z is part of y http://purl.obolibrary.org/obo/RO_0002226 develops in http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x develops_in y if x is located in y whilst x is developing http://purl.obolibrary.org/obo/RO_0002229 ends http://purl.obolibrary.org/obo/BFO_0000050 part_of inverse of ends with http://purl.obolibrary.org/obo/RO_0002230 ends with http://purl.obolibrary.org/obo/RO_0002222 temporally related to x ends with y if and only if x has part y and the time point at which x ends is equivalent to the time point at which y ends. Formally: α(y) > α(x) ∧ ω(y) = ω(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point. http://purl.obolibrary.org/obo/RO_0002231 has start location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has starts location' y if and only if there exists some process z such that x 'starts with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002232 has end location http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in x 'has end location' y if and only if there exists some process z such that x 'ends with' z and z 'occurs in' y http://purl.obolibrary.org/obo/RO_0002256 developmentally induced by http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by t1 induced_by t2 if there is a process of developmental induction (GO:0031128) with t1 and t2 as interacting participants. t2 causes t1 to change its fate from a precursor material anatomical entity type T to T', where T' develops_from T http://purl.obolibrary.org/obo/RO_0002257 developmentally induces http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce Inverse of developmentally induced by http://purl.obolibrary.org/obo/RO_0002285 developmentally replaces http://purl.obolibrary.org/obo/RO_0002258 developmentally preceded by x developmentally replaces y if and only if there is some developmental process that causes x to move or to cease to exist, and for the site that was occupied by x to become occupied by y, where y either comes into existence in this site or moves to this site from somewhere else http://purl.obolibrary.org/obo/RO_0002292 expresses http://purl.obolibrary.org/obo/RO_0002330 genomically related to y expresses x if and only if there is a gene expression process (GO:0010467) that occurs in y, and one of the following holds: (i) x is a gene, and x is transcribed into a transcript as part of the gene expression process (ii) x is a transcript, and x was transcribed from a gene as part of the gene expression process (iii) x is a mature gene product (protein or RNA), and x was translated or otherwise processed from a transcript that was transcribed as part of the gene expression process. http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002324 developmentally related to p results in the developmental progression of s iff p is a developmental process and s is an anatomical entity and p causes s to undergo a change in state at some point along its natural developmental cycle (this cycle starts with its formation, through the mature structure, and ends with its loss). http://purl.obolibrary.org/obo/RO_0002296 results in development of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of p 'results in development of' c if and only if p is a developmental process and p results in the state of c changing from its initial state as a primordium or anlage through its mature state and to its final state. http://purl.obolibrary.org/obo/RO_0002298 results in morphogenesis of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with the process that results in the formation and shaping of that entity over time from an immature to a mature state. http://purl.obolibrary.org/obo/RO_0002299 results in maturation of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links an entity with a process that results in the progression of the entity over time that is independent of changes in it's shape and results in an end point state of that entity. http://purl.obolibrary.org/obo/RO_0015003 subcluster of http://purl.obolibrary.org/obo/BFO_0000050 part_of A relation between a group and another group it is part of but does not fully constitute. http://purl.obolibrary.org/obo/RO_0015015 has high plasma membrane amount http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part A relation between a cell and molecule or complex such that every instance of the cell has a high number of instances of that molecule expressed on the cell surface. http://purl.obolibrary.org/obo/RO_0015016 has low plasma membrane amount http://purl.obolibrary.org/obo/RO_0002104 has plasma membrane part A relation between a cell and molecule or complex such that every instance of the cell has a low number of instances of that molecule expressed on the cell surface. http://purl.obolibrary.org/obo/RO_0002315 results in acquisition of features of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of The relationship that links a specified entity with the process that results in an unspecified entity acquiring the features and characteristics of the specified entity http://purl.obolibrary.org/obo/RO_0002338 has target start location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from some initial location l to some destination. http://purl.obolibrary.org/obo/RO_0002339 has target end location http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in This relationship holds between p and l when p is a transport or localization process in which the outcome is to move some cargo c from a an initial location to some destination l. http://purl.obolibrary.org/obo/RO_0002341 results in transport along http://purl.obolibrary.org/obo/RO_0002337 related via localization to Holds between p and l when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that is aligned_with l http://purl.obolibrary.org/obo/RO_0002342 results in transport across http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in Holds between p and m when p is a transportation or localization process and the outcome of this process is to move c from one location to another, and the route taken by c follows a path that crosses m. http://purl.obolibrary.org/obo/RO_0002386 has potential to developmentally induce http://purl.obolibrary.org/obo/RO_0002384 has developmental potential involving x has potential to developmentally induce y iff x developmentally induces y or x is capable of developmentally inducing y http://purl.obolibrary.org/obo/RO_0002407 indirectly positively regulates http://purl.obolibrary.org/obo/RO_0012012 indirectly regulates p indirectly positively regulates q iff p is indirectly causally upstream of q and p positively regulates q. http://purl.obolibrary.org/obo/RO_0002413 provides input for http://purl.obolibrary.org/obo/RO_0002414 transitively provides input for p provides input for q iff p is immediately causally upstream of q, and there exists some c such that p has_output c and q has_input c. http://purl.obolibrary.org/obo/RO_0002414 transitively provides input for http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect transitive form of directly_provides_input_for http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of http://purl.obolibrary.org/obo/RO_0002431 involved in or involved in regulation of c involved in regulation of p if c is involved in some p' and p' regulates some p http://purl.obolibrary.org/obo/RO_0002429 involved in positive regulation of http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of c involved in regulation of p if c is involved in some p' and p' positively regulates some p http://purl.obolibrary.org/obo/RO_0002430 involved in negative regulation of http://purl.obolibrary.org/obo/RO_0002428 involved in regulation of c involved in regulation of p if c is involved in some p' and p' negatively regulates some p http://purl.obolibrary.org/obo/RO_0002432 is active in http://purl.obolibrary.org/obo/RO_0002328 functionally related to c executes activity in d if and only if c enables p and p occurs_in d. Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure. http://purl.obolibrary.org/obo/RO_0002450 directly positively regulates activity of http://purl.obolibrary.org/obo/RO_0002448 directly regulates activity of The entity A, immediately upstream of the entity B, has an activity that positively regulates an activity performed by B. For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B. http://purl.obolibrary.org/obo/RO_0002565 results in movement of http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure Holds between p and c when p is locomotion process and the outcome of this process is the change of location of c http://purl.obolibrary.org/obo/RO_0002570 conduit for http://purl.obolibrary.org/obo/RO_0002131 overlaps x is a conduit for y iff y overlaps through the lumen_of of x, and y has parts on either side of the lumen of x. http://purl.obolibrary.org/obo/RO_0002578 directly regulates http://purl.obolibrary.org/obo/RO_0002211 regulates p directly regulates q iff p is immediately causally upstream of q and p regulates q. http://purl.obolibrary.org/obo/RO_0002586 results in breakdown of http://purl.obolibrary.org/obo/RO_0002233 has input p results in breakdown of c if and only if the execution of p leads to c no longer being present at the end of p http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0040036 results in changes to anatomical or cellular structure p results in organization of c iff p results in the assembly, arrangement of constituent parts, or disassembly of c http://purl.obolibrary.org/obo/RO_0002629 directly positively regulates http://purl.obolibrary.org/obo/RO_0002578 directly regulates p directly positively regulates q iff p is immediately causally upstream of q, and p positively regulates q. http://purl.obolibrary.org/obo/RO_0002630 directly negatively regulates http://purl.obolibrary.org/obo/RO_0002578 directly regulates p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q. http://purl.obolibrary.org/obo/RO_0002343 results in growth of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002297 results in formation of http://purl.obolibrary.org/obo/RO_0002295 results in developmental progression of http://purl.obolibrary.org/obo/RO_0002287 part of developmental precursor of http://purl.obolibrary.org/obo/RO_0002286 developmentally succeeded by http://purl.obolibrary.org/obo/RO_0002405 immediately causally downstream of http://purl.obolibrary.org/obo/RO_0002404 causally downstream of http://purl.obolibrary.org/obo/RO_0002017 has component activity http://purl.obolibrary.org/obo/RO_0002018 has component process http://purl.obolibrary.org/obo/RO_0002447 phosphorylates http://purl.obolibrary.org/obo/RO_0002436 molecularly interacts with http://purl.obolibrary.org/obo/RO_0002559 causally influenced by http://purl.obolibrary.org/obo/RO_0002506 causal relation between entities http://purl.obolibrary.org/obo/RO_0002006 has synaptic terminal of http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002360 has dendrite location http://purl.obolibrary.org/obo/RO_0002131 overlaps http://purl.obolibrary.org/obo/RO_0002354 formed as result of http://purl.obolibrary.org/obo/RO_0002353 output of http://purl.obolibrary.org/obo/RO_0002485 receives input from http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0002486 sends output to http://purl.obolibrary.org/obo/RO_0002170 connected to http://purl.obolibrary.org/obo/RO_0004032 acts upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002264 acts upstream of or within http://purl.obolibrary.org/obo/RO_0004046 causally upstream of or within, negative effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0004047 causally upstream of or within, positive effect http://purl.obolibrary.org/obo/RO_0002418 causally upstream of or within http://purl.obolibrary.org/obo/RO_0002588 results in assembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0002344 results in transport to from or in http://purl.obolibrary.org/obo/RO_0002337 related via localization to http://purl.obolibrary.org/obo/RO_0002590 results in disassembly of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0012008 results in fusion of http://purl.obolibrary.org/obo/RO_0002592 results in organization of http://purl.obolibrary.org/obo/RO_0002330 genomically related to holds between two entities when some genome-level process such as gene expression is involved. This includes transcriptional, spliceosomal events. These relations can be used between either macromolecule entities (such as regions of nucleic acid) or between their abstract informational counterparts. http://purl.obolibrary.org/obo/RO_0002134 innervates Relation between a 'neuron projection bundle' and a region in which one or more of its component neuron projections either synapses to targets or receives synaptic input. T innervates some R Expands_to: T has_fasciculating_neuron_projection that synapse_in some R. http://purl.obolibrary.org/obo/RO_0002005 innervated by relation between an anatomical structure and a neuron projection bundle that has synaptic terminals in the structure. http://purl.obolibrary.org/obo/RO_0002410 causally related to relation that links two events, processes, states, or objects such that one event, process, state, or object (a cause) contributes to the production of another event, process, state, or object (an effect) where the cause is partly or wholly responsible for the effect, and the effect is partly or wholly dependent on the cause. http://purl.obolibrary.org/obo/RO_0002479 has part that occurs in p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c. http://purl.obolibrary.org/obo/RO_0002337 related via localization to A relationship that holds via some process of localization http://purl.obolibrary.org/obo/IDO_0000660 results_in http://purl.obolibrary.org/obo/uberon/core#channel_for channel for http://purl.obolibrary.org/obo/uberon/core#protects protects http://purl.obolibrary.org/obo/uberon/core#subdivision_of subdivision of http://purl.obolibrary.org/obo/RO_0015002 exemplar data of http://purl.obolibrary.org/obo/GOREL_0002003 results_in_distribution_of