Term IRI	Term label	Parent term IRI	Parent term label	Alternative term	Definition
http://purl.obolibrary.org/obo/UPa_UPA00003	uridine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00570	pyrimidine metabolism		Metabolism of uridine, a pyrimidine derivative compound.
http://purl.obolibrary.org/obo/UPa_UPA00004	thymidine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00570	pyrimidine metabolism		Metabolism of thymidine (deoxythymidine, deoxyribosylthymine, thymine deoxyriboside) a pyrimidine deoxynucleoside very widely distributed.
http://purl.obolibrary.org/obo/UPa_UPA00005	1,3-dichloropropene degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of 1,3-dichloropropene. 1,3-Dichloropropene is used in organic synthesis and as a soil fumigant, it is possibly carcinogenic to humans (Group 2B).
http://purl.obolibrary.org/obo/UPa_UPA00006	1,2-dibromoethane degradation	http://purl.obolibrary.org/obo/UPa_UPA00007	haloalkane degradation		Degradation of 1,2-dibromoethane. 1,2-dibromoethane is a manufactured chemical. It also occurs naturally in small amounts in the ocean where it is formed, probably by algae and kelp. Other names for 1,2-dibromoethane are ethylene dibromide, EDB, and glycol bromide. It is possibly carcinogenic to humans (Group 2B).
http://purl.obolibrary.org/obo/UPa_UPA00007	haloalkane degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of haloalkane compounds, a group of chemical compounds, consisting of alkanes, such as methane or ethane, with one or more halogens linked, such as chlorine or fluorine, making them a type of organic halide.
http://purl.obolibrary.org/obo/UPa_UPA00009	anthocyanin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of anthocyanin compounds. Anthocyanins are water-soluble vacuolar flavonoid pigments that appear red to blue, according to pH. They are synthesized by organisms of the plant kingdom and bacteria. They have been observed to occur in all tissues of higher plants, providing color in leaves, stems, roots, flowers, and fruits.
http://purl.obolibrary.org/obo/UPa_UPA00011	mycobactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of mycobactins, a family of membrane-associated siderophores required for Mycobacterium genus to adapt to its intracellular habitat. Mycobactins contain a salicylic acid-derived moiety.
http://purl.obolibrary.org/obo/UPa_UPA00013	bacillibactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of catecholic siderophore 2,3-dihydroxybenzoate-glycine- threonine trimeric ester bacillibactin.
http://purl.obolibrary.org/obo/UPa_UPA00014	aerobactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of hydroxamate siderophore aerobactin.
http://purl.obolibrary.org/obo/UPa_UPA00015	amonabactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of amonabactin a phenolate siderophore containing 2,3-dihydroxybenzoic acid (2,3-DHB).
http://purl.obolibrary.org/obo/UPa_UPA00016	anguibactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of anguibactin siderophore.
http://purl.obolibrary.org/obo/UPa_UPA00017	enterobactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of siderophore enterobactin, a compound that transports iron from the bacterial environment into the cell cytoplasm. In Escherichia coli, the siderophore molecule enterobactin is synthesized in response to iron deprivation by formation of an amide bond between 2,3-dihydroxybenzoate (2,3-DHB) and l-serine and formation of ester linkages between three such N-acylated serine residues.
http://purl.obolibrary.org/obo/UPa_UPA00018	ornibactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of ornibactin, a linear hydroxamate/hydroxycarboxylate siderophore similar in structure to the pyoverdines.
http://purl.obolibrary.org/obo/UPa_UPA00019	pyoverdin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of pyoverdin (fluorescein, psudobactin), a yellow-green fluorescent siderophore. It is similar in structure to ornibactin.
http://purl.obolibrary.org/obo/UPa_UPA00020	rhizobactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of rhizobactin, an hydroxymate siderophore produced by Sinorhizobium meliloti.
http://purl.obolibrary.org/obo/UPa_UPA00021	vulnibactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of phenolate siderophore vulnibactin. Vulnibactin is produced by Vibrio vulnificus, a human pathogen. Vulnibactin is characterized as containing one residue of 2,3-dihydroxybenzoic acid as well as two residues of salicylic acid, both of which are involved in the formation of oxazoline rings with L-threonine bound to a norspermidine backbone.
http://purl.obolibrary.org/obo/UPa_UPA00022	vibriobactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of peptide vibriobactin siderophore. Vibriobactin is produced by the pathogenic Vibrio cholerae. It is assembled by a four-subunit nonribosomal peptide synthetase complex, VibE, VibB, VibH, and VibF, using 2,3-dihydroxybenzoate and L-threonine as precursors to two 2,3-dihydroxyphenyl- methyloxazolinyl groups in amide linkage on a norspermidine scaffold.
http://purl.obolibrary.org/obo/UPa_UPA00023	alcaligin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of dihydroxamate siderophore alcaligin (Alc), a cyclic dimer of succinyl-N-hydroxy-C-hydroxy-putrescine. Alcaligin is produced by Bordetella bronchiseptica, a Gram- coccobacillus that causes upper respiratory tract illness in several mammalian hostsability to acquire Fe from the mammalian host is associated with virulence.
http://purl.obolibrary.org/obo/UPa_UPA00024	pseudomonine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of pseudomonine siderophore. Pseudomonine is a isoxazolidone derivative produced by Pseudomonas fluorescens.
http://purl.obolibrary.org/obo/UPa_UPA00025	salicylate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of siderophore salicylic acid.
http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism	http://purl.obolibrary.org/obo/UPa_UPA00001	biological process		The totality of the chemical reactions and physical changes that occur in living organisms, comprising anabolism and catabolism; may be qualified to mean the chemical reactions and physical processes undergone by a particular substance, or class of substances, in a living organism. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
http://purl.obolibrary.org/obo/UPa_UPA00027	xenobiotic metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of xenobiotic. Xenibiotics are chemical substances that are foreign to the biological system. They include naturally occurring compounds, drugs, environmental agents, carcinogens, insecticides, etc.
http://purl.obolibrary.org/obo/UPa_UPA00030	lipopolysaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00938	membrane lipid biosynthesis		Biosynthesis of lipopolysaccharide (LPS). LPS comprises three parts: i) polysaccharide (O) side chains (O-antigen); ii) core oligosaccharide; iii) lipid A. Lipid A contains unusual fatty acids (e.g. hydroxy-myristic acid) and is inserted into the outer membrane while the rest of the LPS projects from the surface. Core oligosaccharide contains unusual sugars (e.g. KDO, keto-deoxyoctulonate and heptulose). It contains two glucosamine sugar derivatives each containing three fatty acids with phosphate or pyrophosphate attached. The core polysaccharide is attached to lipid A, which is also in part responsible for the toxicity of gram-negative bacteria. The polysaccharide side chain is referred as the O-antigen of the bacteria. O side chain (O-antigen) is also a polysaccharide chain that extends from the core polysaccharide. LPS are major components of the cell wall of Gram-negative bacteria, contributing greatly to the structural integrity of the bacteria, and protecting the membrane from certain kinds of chemical attack. By increasing the negative charge of the cell wall LSP helps stabilize the overall membrane structure. LPS forms the amphipathic interface between Gram-negative bacteria and their environment and contributes protection against antibiotics and the complement system. The alternative name, endotoxin, is indicative of the capacity to cause septic shock by hyperstimulation of the immune system.
http://purl.obolibrary.org/obo/UPa_UPA00037	4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N) is a strategy adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.
http://purl.obolibrary.org/obo/UPa_UPA00039	acetoin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00409	ketone biosynthesis		Biosynthesis of acetoin (3-hydroxy-2-butanone). Acetoin is a component of the butanediol cycle (butanediol fermentation) in microorganisms.
http://purl.obolibrary.org/obo/UPa_UPA00040	acetoin degradation	http://purl.obolibrary.org/obo/UPa_UPA00410	ketone degradation		Degradation of acetoin (3-hydroxy-2-butanone). Acetoin is a component of the butanediol cycle (butanediol fermentation) in microorganisms.
http://purl.obolibrary.org/obo/UPa_UPA00045	nitrogen metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The chemical reactions and physical changes involving various organic and inorganic nitrogenous compounds; includes nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
http://purl.obolibrary.org/obo/UPa_UPA00054	daunorubicin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00127	anthracycline biosynthesis		Biosynthesis of daunorubicin, a potent antitumor anthracycline antibiotics produced by Streptomyces peucetius.
http://purl.obolibrary.org/obo/UPa_UPA00062	steroid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00504	steroid metabolism		The formation from simpler components of steroid compounds. A steroid is a terpenoid lipid characterized by a carbon skeleton with four fused rings, generally arranged in a 6-6-6-5 fashion. Steroids vary by the functional groups attached to these rings and the oxidation state of the rings. Hundreds of distinct steroids are found in plants, animals, and fungi. All steroids are made in cells either from the sterol lanosterol (animals and fungi) or the sterol cycloartenol (plants). Both sterols are derived from the cyclization of the triterpene squalene.
http://purl.obolibrary.org/obo/UPa_UPA00063	cholesterol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00766	sterol biosynthesis		Cholesterol biosynthesis springs from a six-carbon intermediate called mevalonate. Cholesterol is found in all eukaryotic cells. Its primary function is to regulate membrane fluidity by altering the packing density of the polar membrane lipids. It is also a precursor of several hormones. Its synthesis from acetyl CoA can be separated into 5 stages, all occuring in the cytosol: - mevalonate biosynthesis, - phosphorylation and decarboxylation of mevalonate: isopentenyl-PP biosynthesis and conversion to dimethylallyl-PP - squalene biosynthesis - conversion of squalene to 7-dehydrocholesterol - cholesterol biosynthesis: cholesterol from 7-dehydrocholesterol Cholesterol is used in the body as a precursor of many other important molecules: bile acids (salts), sex steroid hormones (testosterone, estrogen), adrenal steroid hormones (cortisol, aldosterone, vitamin D).
http://purl.obolibrary.org/obo/UPa_UPA00065	5,6,7,8-tetrahydromethanopterin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of 5,6,7,8-tetrahydromethanopterin (H4MPT), a cofactor in methanogenesis. H4MPT is the carrier of the C1 group as it is reduced to the methyl level, before transferring to the coenzyme M.
http://purl.obolibrary.org/obo/UPa_UPA00066	streptomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of streptomycin, an antibiotic produced by soil bacteria of the genus Streptomyces. Streptomycin is active against both gram-positive and gram-negative bacteria. Originally isolated by Selman A. Waksman and Albert Schatz in 1947, streptomycin is effective against tubercle bacilli and is a mainstay of tuberculosis therapy. Streptomycin acts by inhibiting protein synthesis and damaging cell membranes in susceptible microorganisms.
http://purl.obolibrary.org/obo/UPa_UPA00069	5,6,7,8-tetrahydrosarcinapterin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of 5,6,7,8-tetrahydrosarcinapterin (H4SPT), a modified form of H4MPT (5,6,7,8-tetrahydromethanopterin), wherein a glutamyl group linked to the 2-hydroxyglutaric acid terminus.
http://purl.obolibrary.org/obo/UPa_UPA00070	UMP biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00572	UMP biosynthesis		De novo biosynthesis of UMP (uridine monophosphate).
http://purl.obolibrary.org/obo/UPa_UPA00071	coenzyme F420 biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of coenzyme F420, an important cofactor involved in hydride transfer reactions in methanogenic archaea as well as methanotrophic and other bacteria. Although coenzyme F420 contains a deazaflavin moiety, it is biochemically analogous to the nicotinamide cofactors. Coenzyme F420 is involved in a variety of biochemical transformations, including methanogenesis, DNA photorepair, and degradation of nitrophenols and nitroimidazofurans, and in the biosynthesis of several secondary metabolites [PMID:16585745]. F420 is named for its intense fluorescence upon excitation with 420 nm light, the oxidized coenzyme F420 (N-(N -l-lactyl-gamma-glutamyl)-l-glutamic acid phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin) was first discovered in mycobacteria (Cousins 1960) and later purified for structural identification from the methane-producing microorganism Methanobacterium sp. strain M.o.H. (Cheeseman et al. 1972; Eirich et al. 1978). Since these original studies, F420 has been found in numerous actinomycetes and in all methanogens (Isabelle et al. 2002). [PMID:14593448].
http://purl.obolibrary.org/obo/UPa_UPA00072	coenzyme F0 biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of coenzyme F0 (7,8-didemethyl-8-hydroxy-5-deazariboflavin), a biosynthetic precursor of coenzyme F420. Most cyanobacteria and halophilic archaea produce a DNA photolyase enzyme that uses F0 as a coenzyme.
http://purl.obolibrary.org/obo/UPa_UPA00073	L-arginine degradation	http://purl.obolibrary.org/obo/UPa_UPA00429	L-arginine metabolism		Degradation of L-arginine, an energy-rich amino-acid that can supply nitrogen, carbon and energy to various bacteria in a variety of environment. L-arginine can be catabolized by a large number of routes including the arginase pathway, the arginine deiminase (ADI) pathway, the arginine succinyl transferase (AST) pathway, the arginine decarboxylase (ADC), transaminase, oxidase and oxygenase pathways. These pathways often have distinctive functions.
http://purl.obolibrary.org/obo/UPa_UPA00079	menaquinone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00829	quinol/quinone biosynthesis		Biosynthesis of menaquinone (vitamine K2), a lipid-soluble molecule that belongs to the naphto-quinone family.
http://purl.obolibrary.org/obo/UPa_UPA00080	methanofuran biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of methanofuran, the first coenzyme in the methanogenic pathway used by the archaeon Methanocaldococcus jannaschii, as well as other methanogens, to reduce CO2 to methane.
http://purl.obolibrary.org/obo/UPa_UPA00082	naphthalene degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of naphtalene, an aromatic compound composed of two fused benzene rings.
http://purl.obolibrary.org/obo/UPa_UPA00083	3-chlorocatechol degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of 3-chlorocatechol compound. This pathway serves a vital role in the biodegradation of toxic aromatic compounds introduced in the environment both as natural products and as industrial effluent.
http://purl.obolibrary.org/obo/UPa_UPA00085	phospholipid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Metabolism of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
http://purl.obolibrary.org/obo/UPa_UPA00086	alpha-glycerophosphate cycle	http://purl.obolibrary.org/obo/UPa_UPA00085	phospholipid metabolism		The alpha-glycerophosphate cycle is essential for the production of energy for flight in insects.
http://purl.obolibrary.org/obo/UPa_UPA00089	deoxyribonucleotide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00424	nucleotide biosynthesis		Biosynthesis of deoxyribonucleotide derivatives. compounds.
http://purl.obolibrary.org/obo/UPa_UPA00090	abscisate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of abscisic acid (ABA), a sesquiterpenoid (15-carbon) plant hormon. Abscisic acid is partially produced via the mevalonic pathway in chloroplasts and other plastids. Because it is synthesized partially in the chloroplasts, it makes sense that biosynthesis primarily occurs in the leaves. The production of ABA is accentuated by stresses such as water loss and freezing temperatures.
http://purl.obolibrary.org/obo/UPa_UPA00091	photosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00426	energy metabolism		Photosynthesis is a biochemical process in which plants, algae, and some bacteria harness the energy of light to produce simple nutrient molecules, such as glucose. During photosynthesis, simple sugars are produced by combining carbon dioxide and water using light (sunlight) as an energy source and producing oxygen as a by-product. Notice that some forms of photosynthesis do not release oxygen. The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds. [source: GO] The carboxylation process is generally known as CO2 fixation (carbon fixation), and the oxygenation process is known as photorespiration.
http://purl.obolibrary.org/obo/UPa_UPA00092	electron transfer	http://purl.obolibrary.org/obo/UPa_UPA00426	energy metabolism		A process whereby a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient. [GO].
http://purl.obolibrary.org/obo/UPa_UPA00093	abscisic acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00439	plant hormone degradation		Degradation of plant hormone abscisic acid.
http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00420	lipid biosynthesis		Biosynthesis of fatty acids. Fatty acids are formed by the action of Fatty acid synthases from acetyl-CoA and malonyl-CoA precursors.
http://purl.obolibrary.org/obo/UPa_UPA00095	oleic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis		Biosynthesis of oleic acids, a group of fatty acids that contain 18 carbon atoms and a double bond at the omega 9 carbon.
http://purl.obolibrary.org/obo/UPa_UPA00096	sulfur metabolism	http://purl.obolibrary.org/obo/UPa_UPA00426	energy metabolism		Metabolism of compound containing sulfur.
http://purl.obolibrary.org/obo/UPa_UPA00097	sulfate assimilation	http://purl.obolibrary.org/obo/UPa_UPA00096	sulfur metabolism		The sulfate assimilation pathway leads to the biosynthesis of cysteine and methionine, and to the sulfation of proteins, carbohydrates, lipids, drugs and xenobiotics.
http://purl.obolibrary.org/obo/UPa_UPA00099	phenazine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control.
http://purl.obolibrary.org/obo/UPa_UPA00100	bacilysin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of bacilysin (L-alanyl-(2.3-epoxycyclohexanone-4)-L-alanine). This dipeptide is one of the simplest peptide antibiotics known. It displays activity against some bacteria and fungi (Kenig and Abraham 1976; Tschen 1990). Its proposed amino-acid ligase mode of biosynthesis might offer strategies to engineer new derivatives with improved properties. Bacilysin contains an L-alanine residue at the N terminus and a non-proteinogenic amino acid, Lanticapsin, at the C terminus (Walker and Abraham 1970). Its antibiotic activity depends on the anticapsin moiety, which becomes released by peptidases (Kenig et al. 1976; Chmara et al. 1982) after bacilysin uptake into susceptible cells by a distinct peptide permease system (Perry and Abraham 1979; Chmara et al. 1981). The intracellular anticapsin then blocks the glucosamine synthetase, and hence, bacterial peptidoglycan or fungal mannoprotein biosynthesis. This leads to cell protoplasting and lysis (Whitnney and Funderburk 1970; Kenig et al. 1976; Chmara et al. 1982; Chmara 1985; Milewski 1993).
http://purl.obolibrary.org/obo/UPa_UPA00101	candicidin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of candicidin, an aromatic polyene (heptaene) antibiotic produced by Streptomyces griseus IMRU 3570. Polyene macrolides are a group of polyketides with lactone rings of 20-44 members. Candicidin was first described by Lechevalier et al. (1953) and named antibiotic C135, although it was renamed candicidin because of its strong activity against species of Candida.
http://purl.obolibrary.org/obo/UPa_UPA00102	gramicidin S biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of gramicidin S antibiotic. The linear pentadecapeptide gramicidin has been reported to be assembled by four large multimodular nonribosomal peptide synthetases (NRPSs), LgrABCD, that comprise 16 modules. During biosynthesis, the N-formylated 16mer peptide is bound to the peptidyl carrier protein (PCP) of the terminal module via a thioester bond to the carboxyl group of the last amino-acid glycine(16). In a first reaction the peptide is released from the protein template in an NAD(P)H-dependent reduction step catalyzed by the adjacent reductase forming an aldehyde intermediate. This aldehyde intermediate is further reduced by an aldoreductase, LgrE, in an NADPH-dependent manner to form the final product gramicidin A, N -formyl-pentadecapeptide-ethanolamine.
http://purl.obolibrary.org/obo/UPa_UPA00103	L-sorbose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of the monosaccharide L-sorbose.
http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation	http://purl.obolibrary.org/obo/UPa_UPA00027	xenobiotic metabolism		The breakdown into simpler components of xenobiotics, chemical substances that are foreign to the biological system.
http://purl.obolibrary.org/obo/UPa_UPA00107	nicotine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00446	alkaloid biosynthesis		Biosynthesis of nicotine, the primary alkaloid found in tobacco plants.
http://purl.obolibrary.org/obo/UPa_UPA00110	cocaine degradation	http://purl.obolibrary.org/obo/UPa_UPA00447	alkaloid degradation		Degradation of the alkaloid cocaine.
http://purl.obolibrary.org/obo/UPa_UPA00114	xylan degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of xylan, a polymer of xylose residues.
http://purl.obolibrary.org/obo/UPa_UPA00116	Calvin cycle	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		In the Calvin cycle, the source of the carbon atoms is the simple molecule carbon dioxide. In this extremely important process, carbon dioxide gas is trapped in a form that is useful for many processes. The Calvin cycle brings into living systems the carbon atoms that will become constituents of nucleic acids, proteins, and fats. Photosynthetic organisms are called autotrophs (literally self- feeders) because they can synthesize glucose from carbon dioxide and water, by using sunlight as an energy source, and then recover some of this energy from the synthesized glucose through the glycolytic pathway and aerobic metabolism. Organisms that obtain energy from chemical fuels only are called heterotrophs, which ultimately depend on autotrophs for their fuel. The Calvin cycle also differs from gluconeogenesis in where it takes place in photosynthetic eukaryotes. Whereas gluconeogenesis takes place in the cytoplasm, the Calvin cycle takes place in the stroma of chloroplasts, the photosynthetic organelles. The pentose phosphate pathway is part of central metabolism. This pathway provides a means by which glucose can be oxidized to generate NADPH and is the source of much of the NADPH that is needed for the biosynthesis of many biomolecules, most notably fats. The pentose phosphate pathway and the Calvin cycle have in common several enzymes and intermediates that attest to an evolutionary kinship. Like glycolysis and gluconeogenesis, these pathways are mirror images of one another: the Calvin cycle uses NADPH to reduce carbon dioxide to generate hexoses, whereas the pentose phosphate pathway breaks down glucose into carbon dioxide to generate NADPH. The Calvin cycle is sometimes referred to as the reductive pentose phosphate pathway. [Stryer, Biochemistry, 2002].
http://purl.obolibrary.org/obo/UPa_UPA00117	carnitine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Metabolism of L-Carnitine (hydroxy-trimethyl aminobutyric acid), a derivative of the amino acid L-lysine. Its name is derived from the fact that it was first isolated from meat (carnus) in 1905. Because L-carnitine appeared to act as a vitamin in the mealworm (Tenebrio molitor), it was called vitamin BT. Vitamin BT turned out to be a misnomer when scientists discovered that humans and other higher organisms synthesize L-carnitine. Under certain conditions, the demand for L-carnitine may exceed an individual's capacity to synthesize it, making it a conditionally essential nutrient. L-Carnitine is synthesized primarily in the liver and also in the kidneys, and must be transported to other tissues. It is most concentrated in tissues that use fatty acids as their primary dietary fuel, such as skeletal and cardiac (heart) muscle. In this regard, L-carnitine plays an important role in energy production by chaperoning activated fatty acids (acyl-CoA) into the mitochondrial matrix for metabolism and chaperoning intermediate compounds out of the mitochondrial matrix to prevent their accumulation.
http://purl.obolibrary.org/obo/UPa_UPA00118	carnitine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis		The formation from simpler components of carnitine (hydroxy-trimethyl aminobutyric acid). L-Carnitine is synthesized primarily in the liver and also in the kidneys, and must be transported to other tissues.
http://purl.obolibrary.org/obo/UPa_UPA00119	xanthosine degradation	http://purl.obolibrary.org/obo/UPa_UPA00607	purine nucleoside degradation		Degradation of xanthosine, a purine nucleoside.
http://purl.obolibrary.org/obo/UPa_UPA00123	biopolymer modification	http://purl.obolibrary.org/obo/UPa_UPA00316	biopolymer metabolism		The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological polymer, resulting in a change in its properties [GO:0043412].
http://purl.obolibrary.org/obo/UPa_UPA00124	dTDP-L-rhamnose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		The formation from simpler components of dTDP-L-rhamnose, a substance composed of L-rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.
http://purl.obolibrary.org/obo/UPa_UPA00125	L-rhamnose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of rhamnose (hexose 6-deoxy-L-mannose).
http://purl.obolibrary.org/obo/UPa_UPA00127	anthracycline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of anthracyclines, a class of antitumor polyketide antibiotic. These compounds are used to treat a wide range of cancers, including (but not limited to) leukemias, lymphomas, and breast, uterine, ovarian, and lung cancers.
http://purl.obolibrary.org/obo/UPa_UPA00129	GDP-L-fucose biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00453	GDP-L-fucose biosynthesis		Biosynthesis of GDP-L-fucose from L-fucose, without de novo synthesis. In the salvage pathway, GDP-L-fucose is synthesized by the action of an L-fucose kinase and GDP-L-fucose pyrophospholylase from free fucose, which is delivered to the cytosol either extracellularly or intracellularly.
http://purl.obolibrary.org/obo/UPa_UPA00131	beta-alanine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00406	nonprotein amino-acid biosynthesis		Biosynthesis of beta-alanine (3-aminopropanoic acid = 3-aminopropanoate), an achiral amino-acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins. It is an intermediate in pantothenic acid (vitamin B5) and coenzyme A (CoA) biosynthesis. In contrast to bacteria, yeast derive the beta-alanine required for pantothenic acid production via polyamine metabolism.
http://purl.obolibrary.org/obo/UPa_UPA00132	L-ascorbate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Biosynthesis of L-ascorbic acid (Asa), a sugar acid with antioxidant properties. L-ascorbate is required as a cofactor in reactions catalyzed by copper-dependent monooxygenases and iron-dependent dioxygenases. L-ascorbic acid can be biosynthesized by plants, some bacteria and many vertebrates, although not in guinea pigs and primates, including humans.
http://purl.obolibrary.org/obo/UPa_UPA00133	L-alanine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-alanine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00137	monoterpene degradation	http://purl.obolibrary.org/obo/UPa_UPA00716	monoterpene metabolism		Degradation of monoterpenes. Monoterpenes can be divided into three major subgroups: linear monoterpenes, monocyclic monoterpenes and bicyclic monoterpenes.
http://purl.obolibrary.org/obo/UPa_UPA00138	gluconeogenesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Gluconeogenesis is the generation of glucose from other organic molecules like lactate, glycerol, and amino-acids. Many 3- and 4-carbon substrates can enter the gluconeogenesis pathway. But the first designated substrate in the gluconeogenic pathway is pyruvate. Gluconeogenesis cannot be considered to be a reverse process of glycolysis, as the three irreversible steps in glycolysis are bypassed in gluconeogenesis. This is done to ensure that glycolysis and gluconeogenesis do not operate at the same time in the cell.
http://purl.obolibrary.org/obo/UPa_UPA00143	protein ubiquitination	http://purl.obolibrary.org/obo/UPa_UPA00462	small protein conjugation		Ubiquitin is a small protein that occurs in all eukaryotic cells. Its main known function is to mark other proteins for destruction, known as proteolysis. The process of marking a protein with ubiquitin (ubiquitinylation, ubiquitylation or ubiquitination) consists of a series of steps [source: wikipedia]: 1. Activation of ubiquitin - ubiquitin is activated in a two-step reaction by an E1 ubiquitin-activating enzyme in a process requiring ATP as an energy source. The initial step involves production of a ubiquitin-adenylate intermediate. The second step transfers ubiquitin to the E1 active site cysteine residue, with release of AMP. This step results in a thioester linkage between the C-terminal carboxyl group of ubiquitin and the E1 cysteine sulfhydryl group. 2. Transfer of ubiquitin from E1 to the active site cysteine of a ubiquitin-conjugating enzyme E2 via a trans(thio)esterification reaction. 3. The final step of the ubiquitinylation cascade generally requires the activity of one of the hundreds of E3 ubiquitin-protein ligases (often termed simply ubiquitin ligase). E3 enzymes function as the substrate recognition modules of the system and are capable of interaction with both E2 and substrate. E3 enzymes possess one of two domains: * The HECT (Homologous to the E6-AP Carboxyl Terminus) domain * The RING domain (or the closely related U-box domain).
http://purl.obolibrary.org/obo/UPa_UPA00144	proteasomal ubiquitin-dependent pathway	http://purl.obolibrary.org/obo/UPa_UPA00468	protein degradation		Degradation of proteins by hydrolysis of their peptide bonds. This process is initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
http://purl.obolibrary.org/obo/UPa_UPA00147	methane degradation	http://purl.obolibrary.org/obo/UPa_UPA00426	energy metabolism		Degradation of methane, the simplest alkane.
http://purl.obolibrary.org/obo/UPa_UPA00150	maltose degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of maltose (malt sugar), a disaccharide formed from two units of glucose joined with an alpha(1-4) linkage.
http://purl.obolibrary.org/obo/UPa_UPA00151	auxin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00887	auxin metabolism		Biosynthesis of auxins. Auxins are natural plant hormone involved in several stages of plant growth and development such as cell elongation, cell division, tissue differentiation, and apical dominance. The biosynthesis and the underlying mechanism of auxins (and cytokinins) action are subjects of intense investigation. Diverse bacterial species possess the ability to produce the auxin phytohormone indole-3-acetic acid (IAA).
http://purl.obolibrary.org/obo/UPa_UPA00152	starch biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of starch, a complex carbohydrate, used by plants as a way to store excess glucose. Starch contains a mixture of two molecules: amylose and amylopectin. Usually these are found in a ratio of 30:70 or 20:80, with amylopectin found in larger amounts than amylose. Starch is often found in the fruit, seeds, rhizomes or tubers of plants.
http://purl.obolibrary.org/obo/UPa_UPA00153	starch degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of starch, a complex carbohydrate, used by plants as a way to store excess glucose. Starch contains a mixture of two molecules: amylose and amylopectin. Usually these are found in a ratio of 30:70 or 20:80, with amylopectin found in larger amounts than amylose. Starch is often found in the fruit, seeds, rhizomes or tubers of plants.
http://purl.obolibrary.org/obo/UPa_UPA00154	flavonoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00711	phenylpropanoid biosynthesis		The formation from simpler components of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
http://purl.obolibrary.org/obo/UPa_UPA00160	tocopherol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of tocopherol, or vitamin E, a fat-soluble vitamin that is an important antioxidant. Natural vitamin E exists in eight different forms or isomers, four tocopherols and four tocotrienols. All isomers have a chromanol ring, with a hydroxyl group which can donate a hydrogen atom to reduce free radicals and a hydrophobic side chain which allows for penetration into biological membranes. There is an alpha, beta, gamma and delta form of both the tocopherols and tocotrienols, determined by the number of methyl groups on the chromanol ring. Each form has its own biological activity. Alpha-tocopherol is the most active form of vitamin E (tocopherol) in humans and is a powerful biological antioxidant.
http://purl.obolibrary.org/obo/UPa_UPA00161	lincomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00469	lincosamide biosynthesis		Biosynthesis of lincomycin A, an antibiotic that comes from the bacteria Streptomyces lincolnensis. It is composed of two moieties, a sugar moiety 6-amino-6,8-dideoxy-1-thio-D-erythro-{alpha}-D-galactooctopyranoside (methylthiolincosaminide) and an amino-acid derivative 4-n-propyl-L-hygric acid, linked by an amide bond.
http://purl.obolibrary.org/obo/UPa_UPA00162	vancomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of vancomycin, a glycopeptide antibiotic that comes from Actonobacteria. Vancomycin acts by inhibiting proper cell wall synthesis in Gram-positive bacteria. The mechanism inhibited, and various factors related to entering the outer membrane of Gram- negative organisms mean that vancomycin is not active against Gram- negative bacteria (except some non-gonococcal species of Neisseria). Specifically, vancomycin prevents incorporation of N-acetylmuramic acid (NAM)- and N-acetylglucosamine (NAG)-peptide subunits into the peptidoglycan matrix; which forms the major structural component of Gram-positive cell walls.
http://purl.obolibrary.org/obo/UPa_UPA00163	glycogen metabolism	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Metabolism of glycogen. This polysaccharide is the principal storage form of glucose (Glc) in animal cells. Glycogen is found in the form of granules in the cytosol in many cell types, and plays an important role in the glucose cycle.
http://purl.obolibrary.org/obo/UPa_UPA00164	glycogen biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of glycogen, the principal storage form of glucose (Glc) in animal cells. Glycogen is found in the form of granules in the cytosol in many cell types, and plays an important role in the glucose cycle.
http://purl.obolibrary.org/obo/UPa_UPA00165	glycogen degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of glycogen, the principal storage form of glucose (Glc) in animal cells. Glycogen is found in the form of granules in the cytosol in many cell types, and plays an important role in the glucose cycle.
http://purl.obolibrary.org/obo/UPa_UPA00166	mersacidin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00472	lantibiotic B biosynthesis		Biosynthesis of mersacidin, a glycopeptide antibiotic that comes from Actonobacteria. Vancomycin acts by inhibiting proper cell wall synthesis in Gram-positive bacteria. The mechanism inhibited, and various factors related to entering the outer membrane of Gram- negative organisms mean that vancomycin is not active against Gram- negative bacteria (except some non-gonococcal species of Neisseria). Specifically, vancomycin prevents incorporation of N-acetylmuramic acid (NAM)- and N-acetylglucosamine (NAG)-peptide subunits into the peptidoglycan matrix; which forms the major structural component of Gram-positive cell walls.
http://purl.obolibrary.org/obo/UPa_UPA00167	heptaketide naphthopyrone YWA1 biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of heptaketide naphthopyrone YWA1. yWA1 is a yellow conidial wall pigment intermediate produced by Emericella nidulans (Aspergillus nidulans).
http://purl.obolibrary.org/obo/UPa_UPA00168	phosphinothricin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of phosphinothricin (2-amino-4-(hydroxymethylphosphinyl)butanoic acid) antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00169	beta-lactam biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of beta-lactam antibiotics, a broad class of antibiotics which include penicillin derivatives, cephalosporins, monobactams, carbapenems and beta-lactamase inhibitors,etc (i.e any antibiotic agent which contains a beta-lactam nucleus in its molecular structure). The beta- lactam ring, or penam, is a lactam with a heteroatomic ring structure, consisting of three carbon atoms and one nitrogen atom.
http://purl.obolibrary.org/obo/UPa_UPA00170	trisporate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00459	pheromone biosynthesis		Biosynthesis of trisporate, a sex pheromone. Trisporate stimulates zygophore (sex cell) development in Mucor mucedo ans presumably in all other mucoraceous fungi including Blakeslea trispora. 4-dihydromethyltrisporate is produced solely by the (+) mating type and released into the environment. (-) Mating types react to the stimulus by directed growth and production of zygophores. 4-dihydromethyltrisporate is taken up by (-) hyphae and converted into methyltrisporate by 4-dihydromethyltrisporate dehydrogenase (TDH). Trisporate is synthesized from methyltrisporate by an esterase. Both enzymatic reactions occur specifically in the (-) mating type.
http://purl.obolibrary.org/obo/UPa_UPA00172	cephalosporin C biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00475	cephalosporin biosynthesis		Biosynthesis of cephalosporin C antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00173	actinorhodin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of actinorhodin polyketide antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00174	tetracenomycin C biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of tetracenomycin C, a polyketide antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00175	granaticin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of granaticin, a polyketide antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00176	curamycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of curamycin, a polyketide antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00178	monensin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00479	antifungal biosynthesis		iosynthesis of monensin, a polyketide antifungal.
http://purl.obolibrary.org/obo/UPa_UPA00179	bacitracin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of bacitracin antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00180	tyrocidine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of tyrocidine antibiotic. Tyrocidine is a mixture of four cyclic decapeptides, tyrocidine A (D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr- Val-Orn-Leu), B, C, and D, in which Phe, at positions 3, 4, and Tyr residues are gradually replaced by Trp, depending on the relative concentrations of these amino-acids in the growth medium.
http://purl.obolibrary.org/obo/UPa_UPA00181	surfactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of surfactin antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00182	carbapenem biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00169	beta-lactam biosynthesis		Biosynthesis of carbapenem (1-carbapen-2-em-3-carboxylic acid), a beta-lactam antibiotic. biosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00183	cephamycin C biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00169	beta-lactam biosynthesis		Biosynthesis of cephamycin C, a beta-lactam antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00184	fortimicin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of fortimicin A (astromicin) antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00187	putrescine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00457	putrescine metabolism		Biosynthesis of putrescine, an essential precursor of the higher polyamines, spermidine and spermine. Putrescine can be formed either directly from L-ornithine or from agmatine (indirectly from L-arginine).
http://purl.obolibrary.org/obo/UPa_UPA00191	alkane degradation	http://purl.obolibrary.org/obo/UPa_UPA00352	hydrocarbon degradation		Degradation of saturated hydrocarbon compounds.
http://purl.obolibrary.org/obo/UPa_UPA00193	tetrahydrofolate interconversion	http://purl.obolibrary.org/obo/UPa_UPA01000	tetrahydrofolate metabolism		C1-unit interconversion via tetrahydrofolate pathway.
http://purl.obolibrary.org/obo/UPa_UPA00194	thyroid hormone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00435	hormone biosynthesis		Biosynthesis of thyroid hormones. The thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are tyrosine-based hormones produced by the thyroid gland. An important component in the synthesis is iodine. The major form of thyroid hormone in the blood is thyroxine (T4).
http://purl.obolibrary.org/obo/UPa_UPA00195	epi-isozizaene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of the tricyclic sesquiterpenoid epi-isozizaene produced by Streptomyces coelicolor.
http://purl.obolibrary.org/obo/UPa_UPA00196	glycosylphosphatidylinositol-anchor biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of GPI or glycosylphosphatidylinositol anchor, a glycolipid that can be attached to the C-terminus of a protein during posttranslational modification. A GPI anchor is composed of a hydrophobic phosphatidyl inositol group linked through a carbohydrate containing linker (glucosamine and mannose linked to phosphoryl ethanolamine residue) to the C-terminal amino-acid of a mature protein. The two fatty acids within the hydrophobic phosphatidyl- inositol group anchor the protein to the cell membrane.
http://purl.obolibrary.org/obo/UPa_UPA00197	bialaphos biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of bialaphos, a secondary metabolite of Streptomyces hygroscopicus, used as herbicide. Bialaphos is a tripeptide which consists of two L-alanine residues and the L-glutamic analog phosphinothrycin.
http://purl.obolibrary.org/obo/UPa_UPA00198	DNA modification	http://purl.obolibrary.org/obo/UPa_UPA00485	genetic information processing		The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties. [GO].
http://purl.obolibrary.org/obo/UPa_UPA00199	fatty acid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Metabolism of fatty acids.
http://purl.obolibrary.org/obo/UPa_UPA00200	stilbene, coumarine and lignin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of stilbene, coumarine and lignin.
http://purl.obolibrary.org/obo/UPa_UPA00201	L-glutamate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism		Metabolism of L-glutamic acid amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00202	fructose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of fructose.
http://purl.obolibrary.org/obo/UPa_UPA00203	methylnaphthalene degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of methylnaphthalene derivative compounds.
http://purl.obolibrary.org/obo/UPa_UPA00204	glutathione metabolism	http://purl.obolibrary.org/obo/UPa_UPA00096	sulfur metabolism		Metabolism of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00205	propanoate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism		Metabolism of propionic acid (propionate, propanoate).
http://purl.obolibrary.org/obo/UPa_UPA00206	ethanol fermentation	http://purl.obolibrary.org/obo/UPa_UPA00612	alcohol degradation		Fermentation of ethanol.
http://purl.obolibrary.org/obo/UPa_UPA00207	nylon-6 oligomer degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of 6-aminohexanoate dimers (cyclic or linear), by-products of nylon manufacture.
http://purl.obolibrary.org/obo/UPa_UPA00209	geosmin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of geosmin (trans-1,10-dimethyl-trans-9-decalol). Geosmin is responsible for the characteristic odor of moist soil, it is produced in soil primarily by streptomycetes-ubiquitous Gram-positive, filamentous, saprophytic bacteria. Geosmin has also been isolated from a variety of cyanobacteria, fungi, and liverworts. Jiang et al [PMID:16787064] established that the biosynthesis of geosmin from farnesyl diphosphate is catalyzed by a single enzyme, the germacradienol/germacrene D synthase, without intervention of any additional enzymes and without any requirement for redox cofactors.
http://purl.obolibrary.org/obo/UPa_UPA00210	purine nucleotide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00583	purine metabolism		Metabolism of purine nucleotides.
http://purl.obolibrary.org/obo/UPa_UPA00211	spermine degradation	http://purl.obolibrary.org/obo/UPa_UPA00456	amine and polyamine degradation		Degradation of the polyamine spermine (N,N'-bis(3-aminopropyl)-1,4-butanediamine).
http://purl.obolibrary.org/obo/UPa_UPA00212	polyhydroxyalkanoate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00487	polyester biosynthesis		Biosynthesis of polyhydroxyalkanoates (PHAs), linear polyesters produced by bacterial fermentation of sugar or lipids.
http://purl.obolibrary.org/obo/UPa_UPA00213	terpenoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of terpenoid compounds.
http://purl.obolibrary.org/obo/UPa_UPA00214	galactose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of galactose.
http://purl.obolibrary.org/obo/UPa_UPA00215	nucleotide-sugar metabolism	http://purl.obolibrary.org/obo/UPa_UPA00486	nucleotide metabolism		Metabolism of nucleotide-sugar compounds.
http://purl.obolibrary.org/obo/UPa_UPA00216	amino-sugar metabolism	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Metabolism of amino-sugar compounds.
http://purl.obolibrary.org/obo/UPa_UPA00217	vanillyl-alcohol degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of vanillyl-alcohol (4-hydroxy-3-methoxybenzenemethanol).
http://purl.obolibrary.org/obo/UPa_UPA00218	L-methionine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		Metabolism of sulfur-containing amino-acid L-methionine (2-amino-4-(methylthio)butanoic acid). L-methionine is an essential amino-acid for many crucial cellular functions, including the initiation of protein synthesis, methylation of DNA and rRNA, and biosynthesis of cysteine, phospholipids and polyamines.
http://purl.obolibrary.org/obo/UPa_UPA00219	peptidoglycan biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00547	cell wall biogenesis		Biosynthesis of peptidoglycan, also known as murein, a polymer consisting of sugars and amino-acids that forms a mesh-like layer outside the plasma membrane of eubacteria. The sugar component consists of alternating residues of beta-(1,4) linked N-acetylglucosamine and N-acetylmuramic acid residues. Attached to the N-acetylmuramic acid is a peptide chain of three to five amino-acids. The peptide chain can be cross-linked to the peptide chain of another strand forming the 3D mesh-like layer. Some Archaea have a similar layer of pseudopeptidoglycan. Peptidoglycan serves a structural role in the bacterial cell wall, giving structural strength, as well as counteracting the osmotic pressure of the cytoplasm. Peptidoglycan is also involved in binary fission during bacterial cell reproduction.[wikipedia].
http://purl.obolibrary.org/obo/UPa_UPA00220	phosphatidylinositol phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00751	phospholipid biosynthesis		Biosynthesis of phosphatidylinositol phosphate, a class of phospholipids.
http://purl.obolibrary.org/obo/UPa_UPA00221	bile acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Biosynthesis of bile acids, any of a group of steroid carboxylic acids occurring in bile [GO].
http://purl.obolibrary.org/obo/UPa_UPA00222	sphingolipid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00939	membrane lipid metabolism		Metabolism of sphingolipid compounds, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). There are three main types of sphingolipids: ceramides, sphingomyelins and glycosphingolipids.
http://purl.obolibrary.org/obo/UPa_UPA00224	tryptophan metabolism	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Metabolism of tryptophan amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00225	lysine degradation	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		Degradation of lysine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00226	Entner-Doudoroff pathway	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Entner-Doudoroff pathway that converts glucose to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it. [GO].
http://purl.obolibrary.org/obo/UPa_UPA00227	glyoxylate and dicarboxylate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of glyoxylate and dicarboxylate.
http://purl.obolibrary.org/obo/UPa_UPA00228	xylene degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of xylene, a mixture of three aromatic hydrocarbon ortho-, meta- and para-xylene.
http://purl.obolibrary.org/obo/UPa_UPA00229	C21-steroid hormone metabolism	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Metabolism of C21-steroid hormone compounds.
http://purl.obolibrary.org/obo/UPa_UPA00230	glycerolipid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00615	glycerol metabolism		Metabolism of glycerolipids.
http://purl.obolibrary.org/obo/UPa_UPA00231	pyruvate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism		Metabolism of pyruvic acid, the simplest alpha-keto acid that plays an important role in biochemical processes.
http://purl.obolibrary.org/obo/UPa_UPA00232	ubiquinone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00975	prenylquinone biosynthesis		Biosynthesis of ubiquinones, lipid-soluble electron-transporting coenzymes. Ubiquinones are essential electron carrier in prokaryotes. Ubiquinones are essential molecules in aerobic organisms to achieve both, ATP synthesis and antioxidant defence.
http://purl.obolibrary.org/obo/UPa_UPA00233	benzoate degradation via CoA ligation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of benzoic acid, by its ligation to Coenzyme-A to form benzoyl-CoA.
http://purl.obolibrary.org/obo/UPa_UPA00234	enniatin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of enniatin derivatives. Enniatins are N-methylated cyclohexadepsipeptides produced by various Fusarium species and with manifold biological properties (Tomoda et al. 1992 [PMID:1399840]). They are composed of alternating residues of D-2-hydroxyisovaleric acid (D-Hiv) and an N-methylated branched-chain amino-acid such as L-valine, L-leucine or L-isoleucine. The biosynthesis of enniatins is catalyzed by the multifunctional enzyme enniatin synthetase (Esyn), which belongs to the class of nonribosomal peptide synthetases (NRPSs). Enniatin belong to ionophore antibiotic class.
http://purl.obolibrary.org/obo/UPa_UPA00235	pyocyanine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of pyocyanin, a blue pigment produced by bacteria such as Pseudomonas spp. Pyocyanin is a redox-active phenazine compound that kills mammalian and bacterial cells through the generation of reactive oxygen intermediates. Pyocyanin produced by Pseudomonas aeruginosa contributes to its ability to colonise the lungs of cystic fibrosis patients.
http://purl.obolibrary.org/obo/UPa_UPA00236	2,4-dichlorobenzoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs). [GO:0046298].
http://purl.obolibrary.org/obo/UPa_UPA00237	beta-glucoside metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of beta-glucoside compounds, glycosides in which the sugar moiety is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
http://purl.obolibrary.org/obo/UPa_UPA00238	sucrose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Metabolism of sucrose (or saccharose, or 1-alpha-D-glucopyranosyl-2-beta-D-fructofuranoside) is a is a disaccharide (glucose + fructose). In most plants, sucrose is the main product of photosynthesis that is exported from the leaves to fuel growth and synthesis of storage reserves, such as starch and oil, and sucrose itself is often accumulated by plant cells to protect against the effects of dehydration under drought, salinity, or cold stress. Apart from plants, some species of cyanobacteria also synthesize sucrose, often in response to osmotic stress.
http://purl.obolibrary.org/obo/UPa_UPA00239	quinoline degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of quinoline, a heterocyclic aromatic organic compound, also known as 1-azanaphthalene, 1-benzazine, or benzo[b]pyridine. Quinoline is an intermediate in metallurgical processes and in dye, polymer, and agrochemical production. It is also a preservative, disinfectant, and solvent.
http://purl.obolibrary.org/obo/UPa_UPA00240	erythromycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of erythromycin (also known as eryth ethylsuc), a macrolide antibiotic which has an antimicrobial spectrum similar to or slightly wider than that of penicillin.
http://purl.obolibrary.org/obo/UPa_UPA00242	hexose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
http://purl.obolibrary.org/obo/UPa_UPA00245	pyridoxal 5'-phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of pyridoxal 5'-phosphate. This pathway corresponds to one of the de novo biosynthesis pathway. The biosynthesis of PLP is performed by a complex reaction: in addition to ammonia transfer PdxS/PdxT catalyzes condensation of two phosphosugars, closure of the pyridine ring, as well as isomerase reactions for its phosphosugar substrates. The complexity of the enzyme correlates well with the strong conservation of the PdxS sequence. Contrary to the alternative PLP biosynthesis pathway (glutamate pathway), this pathway does not require PLP as cofactor in its own synthesis.
http://purl.obolibrary.org/obo/UPa_UPA00246	pentose and glucuronate interconversion	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Pentose and glucuronate interconversion pathway.
http://purl.obolibrary.org/obo/UPa_UPA00247	4-aminobutanoate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00732	4-aminobutanoate metabolism		Biosynthesis of 4-aminobutanoate (GABA).
http://purl.obolibrary.org/obo/UPa_UPA00255	stachydrine degradation	http://purl.obolibrary.org/obo/UPa_UPA00456	amine and polyamine degradation		Degradation of stachydrine, the betaine derivative of proline.
http://purl.obolibrary.org/obo/UPa_UPA00256	triacylglycerol degradation	http://purl.obolibrary.org/obo/UPa_UPA00494	glycerolipid degradation		Degradation of triacylglycerol (triacylglyceride, triglyceride, TAG). Triacylglycerol is a glyceride in which the glycerol is esterified with three fatty acids. It is the main constituent of vegetable oil and animal fats.
http://purl.obolibrary.org/obo/UPa_UPA00264	betaine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis		Biosynthesis of glycine betaine (N,N,N-trimethylglycine), an important osmoprotectant. Glycine betaine is synthesized in response to abiotic stresses. Although almost all known biosynthetic pathways of betaine are oxidation of choline, an alternative pathway converts glycine to betaine through glycine methylation.
http://purl.obolibrary.org/obo/UPa_UPA00266	iron-sulfur cluster biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of iron-sulfur [Fe-S] cluster. Iron-sulfur [Fe-S] clusters are ubiquitous and evolutionary ancient prosthetic groups that are required to sustain fundamental life processes. Owing to their remarkable structural plasticity and versatile chemical/electronic features [Fe-S] clusters participate in electron transfer, substrate binding/activation, iron/sulfur storage, regulation of gene expression, and enzyme activity. Formation of intracellular [Fe-S] clusters does not occur spontaneously but requires a complex biosynthetic machinery. Three different types of [Fe-S] cluster biosynthetic systems have been discovered, and all of them are mechanistically unified by the requirement for a cysteine desulfurase and the participation of an [Fe-S] cluster scaffolding protein. [PMID:15952888].
http://purl.obolibrary.org/obo/UPa_UPA00267	trichothecene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of trichothecenes, a group of sesquiterpenes produced by various Fusarium species like F. graminearum, F. sporotrichioides, F. poae or F. equiseti.
http://purl.obolibrary.org/obo/UPa_UPA00268	bluish-green pigment biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of bluish-green pigment. Bluish-green pigment is produced by Aspergillus fumigatus, a filamentous fungus (an important opportunistic pathogen that primarily affects immunocompromised patients). Conidial pigmentation of A. fumigatus significantly influences its virulence in a murine model.
http://purl.obolibrary.org/obo/UPa_UPA00270	quinolate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00465	secondary metabolite metabolism		metabolism of quinolinate (quinolinic acid), a potent endogenous excitotoxin of neuronal cells. Elevation of quinolinate levels in the brain has been implicated in the pathogenesis of various neurodegenerative disorders, the so-called 'quinolinate hypothesis.' Quinolinate is non- enzymatically derived from alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS). ACMS decarboxylase (ACMSD) is the only known enzyme that can process ACMS to a begnin catabolite and thus prevent the accumulation of quinolinate from ACMS. ACMSD seems to be regulated by nutritional and hormonal signals, but its molecular mechanism has, to date, been largely unknown. [PMID:12140278].
http://purl.obolibrary.org/obo/UPa_UPA00271	ommochrome biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of ommochrome (brown eye pigment). Ommochrome (or visual pigment) refers to several biological pigments that occur in the eyes of crustaceans and insects. The eye color is determined by the ommochromes. Ommochromes are also found in the chromatophores of cephalopods, and in spiders. Ommochromes are metabolites of tryptophan, via kynurenine and 3-hydroxykynurenine. They are responsible for a wide variety of colors, ranging from yellow over red and brown to black. Lighter colors tend to be generated by ommatins, while mixtures of ommatin and ommins are responsible for darker colors.
http://purl.obolibrary.org/obo/UPa_UPA00278	betalain biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of batalains, a class of red and yellow indole-derived pigments found in plants.
http://purl.obolibrary.org/obo/UPa_UPA00279	bile acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Degradation of bile acids, any of a group of steroid carboxylic acids occurring in bile [GO].
http://purl.obolibrary.org/obo/UPa_UPA00280	N-glycan degradation	http://purl.obolibrary.org/obo/UPa_UPA00957	N-glycan metabolism		Degradation of asparagine (N)-linked oligosaccharides (N-glycans).
http://purl.obolibrary.org/obo/UPa_UPA00281	LPS O-antigen biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of O-antigen, the polysaccharide side chain of lipopolysaccharide (LPS) molecules. The composition of the O side chain varies between different gram-negative bacterial strains. O side chains are easily recognized by the antibodies of the host, however, the nature of the chain can easily be modified by Gram-negative bacteria to avoid detection.
http://purl.obolibrary.org/obo/UPa_UPA00282	triacylglycerol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00495	glycerolipid biosynthesis		Biosynthesis of triacylglycerol (triacylglyceride, triglyceride, TAG). Triacylglycerol is glyceride in which the glycerol is esterified with three fatty acids. It is the main constituent of vegetable oil and animal fats.
http://purl.obolibrary.org/obo/UPa_UPA00284	LOS oligosaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00501	lipooligosaccharide biosynthesis		Biosynthesis of the oligosaccharide component of lipooligosaccharide (LOS).
http://purl.obolibrary.org/obo/UPa_UPA00286	alginate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00502	alginate metabolism		Biosynthesis of alginate, an hydrophilic exopolysaccharide produced by brown seaweeds an some bacteria. There is a strong correlation of alginate production with patients suffering from the disease cystic fibrosis caused by some pathogen bacteria (Pseudomonas, Azopbacter). Chemically, alginate is a linear copolymer with homopolymeric blocks of (1-4)-linked beta-D-mannuronate (M) and its C-5 epimer alpha-L-guluronate (G) residues, respectively, covalently linked together in different sequences.
http://purl.obolibrary.org/obo/UPa_UPA00287	aflatoxin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00478	mycotoxin biosynthesis		Biosynthesis of aflatoxin, a family of acutely toxic, teratogenic, potent carcinogenic, and mutagenic metabolites produced by certain strains of common molds Aspergillus flavus and A. parasiticus.
http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Biosynthesis of amines and polyamines. These compounds play a variety of roles in metabolism, including acting as osmoprotectants, keeping DNA in a condensed state, and serving as intermediates in the synthesis of macromolecules. The polyamines, e.g. 1,3-diaminopropane, putrescine, cadaverine, agmatine, spermidine and spermine, are wide-spread in all organisms, and have been shown to play a role in the regulation of growth and differentiation of virtually all types of cells.
http://purl.obolibrary.org/obo/UPa_UPA00293	D-ribose 5-phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Ribose-5-phosphate is generally assumed to arise via the oxidative and nonoxidative pentose phosphate pathways. In some archaea, ribulose monophosphate (RuMP) pathway may be functioning as an alternate route to ribose-5-phosphate. Grochowski et al [PMID: 16237021] showed experimentally that that in M. jannaschii, ribose-5-phosphate is produced exclusively via the RuMP pathway and that these cells do not appear to operate a pentose phosphate pathway.
http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of organic compounds able to kill bacteria, or inhibit their growth.
http://purl.obolibrary.org/obo/UPa_UPA00296	cholesterol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00504	steroid metabolism		Metabolism of cholesterol.
http://purl.obolibrary.org/obo/UPa_UPA00297	dicyanocobinamide salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Dicyanocobinamide is a coenzyme B<sub>12</sub> precursor. Regarding Woodson ate al [PMID:14990804] prokaryotes have evolved at least two distinct pathways for salvaging the precursor cobinamide (Cbi) from the environment. Both pathways accomplish the same goal, which is to convert AdoCbi (adenosylcobinamide) to AdoCbi-P, a true intermediate of the de novo biosynthetic pathway.
http://purl.obolibrary.org/obo/UPa_UPA00298	siderophore metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The chemical reactions and physical changes involving siderophore (siderochromes), low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderochromes have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
http://purl.obolibrary.org/obo/UPa_UPA00299	trehalose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of trehalose, also known as mycose, a disaccharide found extensively but not abundantly in nature. It can be synthesised by fungi, plants and invertebrate animals. It is implicated in anhydrobiosis - the ability of plants and animals to withstand prolonged periods of desiccation.
http://purl.obolibrary.org/obo/UPa_UPA00301	LPS oligosaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of inner core oligosaccharide, a component of lipopolysaccharide (LPS) molecules. Core oligosaccharide contains unusual sugars (e.g. KDO, keto-deoxyoctulonate and heptulose). It contains two glucosamine sugar derivatives each containing three fatty acids with phosphate or pyrophosphate attached. The core polysaccharide is attached to lipid A, which is also in part responsible for the toxicity of gram-negative bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00298	siderophore metabolism		Biosynthesis of iron-sequestering compounds. The production of siderophores is a key feature which enables pathogenic bacteria to survive within the vertebrate host. Siderophores facilitate the solubilization and transport of ferric iron into the cell essential requirement for bacterial growth.
http://purl.obolibrary.org/obo/UPa_UPA00303	atropine degradation	http://purl.obolibrary.org/obo/UPa_UPA00508	tropane alkaloid degradation		Degradation of atropine, a tropan alkaloid.
http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00215	nucleotide-sugar metabolism		Biosynthesis of nucleotide-sugars, any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00305	alkene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00777	alkene metabolism		Biosynthesis of alkene, unsaturated chemical compound containing at least one carbon-to-carbon double bond.
http://purl.obolibrary.org/obo/UPa_UPA00309	violacein biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of violacein, a deep violet pigment produced by Chromobacterium violaceum. The low solubility of violacein in water and the high molar extinction coefficient in methanol lead Antonio and Creczynski-Pasa [PMID:15100990] to suppose that it is involved in protection against visible radiation, since C.violaceum bacterium is widely found in the water and soil of tropical and subtropical areas of the world.
http://purl.obolibrary.org/obo/UPa_UPA00310	ajmaline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00512	terpenoid indole alkaloid biosynthesis		Biosynthesis of ajmaline, an antiarrhythmic monoterpenoid indole alkaloid. The ajmaline biosynthetic pathway expressed in the medicinal plant Rauvolfia serpentina (L.) Benth. ex Kurz. The pathway originates from rather simple precursors such as tryptamine on one side, and the monoterpenoid glucoside secologanin on the other side.
http://purl.obolibrary.org/obo/UPa_UPA00312	nucleotide salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00486	nucleotide metabolism		Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis. [GO].
http://purl.obolibrary.org/obo/UPa_UPA00313	pyrimidine nucleotide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00570	pyrimidine metabolism		Metabolism of pyrimidine nucleotides.
http://purl.obolibrary.org/obo/UPa_UPA00316	biopolymer metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The chemical reactions and pathways involving biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00317	morphine degradation	http://purl.obolibrary.org/obo/UPa_UPA00514	isoquinoline alkaloid degradation		Degradation of morphine, an isoquinolin alkaloid.
http://purl.obolibrary.org/obo/UPa_UPA00318	codeine degradation	http://purl.obolibrary.org/obo/UPa_UPA00514	isoquinoline alkaloid degradation		Degradation of codeine, an isoquinolin alkaloid.
http://purl.obolibrary.org/obo/UPa_UPA00320	biopolymer biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00316	biopolymer metabolism		The chemical reactions and pathways resulting in the formation of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00321	C3 acid pathway	http://purl.obolibrary.org/obo/UPa_UPA00515	carbon fixation		C3 acid pathway is one of the three carbon fixation pathway.
http://purl.obolibrary.org/obo/UPa_UPA00322	C4 acid pathway	http://purl.obolibrary.org/obo/UPa_UPA00515	carbon fixation		C4 acid pathway is one of the three carbon fixation pathway.
http://purl.obolibrary.org/obo/UPa_UPA00323	CAM pathway	http://purl.obolibrary.org/obo/UPa_UPA00515	carbon fixation		Crassulacean Acid Metabolism (CAM) pathway is one of the three carbon fixation pathway.
http://purl.obolibrary.org/obo/UPa_UPA00324	bacterial outer membrane biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00931	cellular component biogenesis		Biogenesis of bacterial outer membrane constituents.
http://purl.obolibrary.org/obo/UPa_UPA00325	hydrocarbon metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of hydrocarbons, organic compound consisting entirely of hydrogen and carbon. Saturated hydrocarbons are called alkanes. Unsaturated hydrocarbons with one double bond are called alkenes.
http://purl.obolibrary.org/obo/UPa_UPA00326	DNA replication	http://purl.obolibrary.org/obo/UPa_UPA00485	genetic information processing		The process whereby new strands of DNA are synthesized. The template for replication can either be an existing DNA molecule or RNA. [GO].
http://purl.obolibrary.org/obo/UPa_UPA00327	ergot alkaloid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00446	alkaloid biosynthesis		Biosynthesis of ergot alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00328	secologanin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00446	alkaloid biosynthesis		Biosynthesis of secologanin, the precursor of the monoterpenoid indole alkaloids and ipecac alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00329	pyrrolizidine alkaloid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00446	alkaloid biosynthesis		Biosynthesis of pyrrolizidine alkaloids. ipecac alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00330	tropane alkaloid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00446	alkaloid biosynthesis		Biosynthesis of tropane alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00335	[NiFe] hydrogenase maturation	http://purl.obolibrary.org/obo/UPa_UPA00516	protein maturation		Maturation of [NiFe] hydrogenase, one of the three hydrogenase class with an active site based on nickel and iron.
http://purl.obolibrary.org/obo/UPa_UPA00337	hopanoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00518	hopanoid metabolism		Biosynthesis of hopanoids, pentacyclic compounds similar to sterols, whose primary function is to improve plasma membrane fluidity in prokaryotes.
http://purl.obolibrary.org/obo/UPa_UPA00338	alkanesulfonate degradation	http://purl.obolibrary.org/obo/UPa_UPA00522	organosulfur degradation		In the absence of sulfate, a number of yeasts can use alkanesulfonates (aliphatic sulfonates), such as taurine, cysteate, and isethionate, as alternative sulfur sources. Sulfonate utilization by Saccharomyces cerevisiae occurs only under aerobic conditions, is independent of sulfate-utilizing enzymes, and requires sulfite reductase, consistent with the formation of sulfite prior to assimilation.
http://purl.obolibrary.org/obo/UPa_UPA00339	mannose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of the aldohexose mannose (the C-2 epimer of glucose). The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins. [GO].
http://purl.obolibrary.org/obo/UPa_UPA00341	hyaluronan biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00519	hyaluronan metabolism		Biosynthesis of hyaluronan, a non-sulfated glycosaminoglycan. Hyaluronan is synthesized by a class of integral membrane proteins called hyaluronan synthases. Vertebrates have three types: HAS1, HAS2, and HAS3. These enzymes lengthen hyaluronan by repeatedly adding glucuronic acid and N-acetylglucosamine to the nascent polysaccharide.
http://purl.obolibrary.org/obo/UPa_UPA00342	N-acetylmuramate degradation	http://purl.obolibrary.org/obo/UPa_UPA00627	amino-sugar degradation		Degradation of N-acetylmuramic acid, an amino-sugar.
http://purl.obolibrary.org/obo/UPa_UPA00343	1,6-anhydro-N-acetylmuramate degradation	http://purl.obolibrary.org/obo/UPa_UPA00627	amino-sugar degradation		Degradation of anhydro-N-acetylmuramate, an amino-sugar.
http://purl.obolibrary.org/obo/UPa_UPA00344	molybdopterin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of molybdopterin, an essential cofactor for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands. [GO:0032324].
http://purl.obolibrary.org/obo/UPa_UPA00345	polypeptide chain elongation	http://purl.obolibrary.org/obo/UPa_UPA00458	protein biosynthesis		Elongation stage in protein biosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00346	dibenzothiophene degradation	http://purl.obolibrary.org/obo/UPa_UPA00096	sulfur metabolism		Desulfurization of dibenzothiophene (DBT) into 2-hydroxybiphenyl (2-HBP).
http://purl.obolibrary.org/obo/UPa_UPA00347	hydrocarbon biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00325	hydrocarbon metabolism		Biosynthesis of hydrocarbons, organic compound consisting entirely of hydrogen and carbon. Saturated hydrocarbons are called alkanes. Unsaturated hydrocarbons with one double bond are called alkenes.
http://purl.obolibrary.org/obo/UPa_UPA00348	2-(2,4-dichlorophenoxy)propanoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of (2,4-dichlorophenoxy)propanoate (dichlorprop, 2,4-DP), a chlorinated phenoxy herbicid.
http://purl.obolibrary.org/obo/UPa_UPA00349	chitin degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of chitin, a glycan composed of beta-1,4-linked N-acetyl-D-glucosamine, into N-acetyl-D-glucosamine.
http://purl.obolibrary.org/obo/UPa_UPA00350	beta-D-glucan degradation	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Degradation of beta-D-glucan.
http://purl.obolibrary.org/obo/UPa_UPA00351	L-glutamate degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of L-glutamate amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00352	hydrocarbon degradation	http://purl.obolibrary.org/obo/UPa_UPA00325	hydrocarbon metabolism		Degradation of hydrocarbons, organic compound consisting entirely of hydrogen and carbon. Saturated hydrocarbons are called alkanes. Unsaturated hydrocarbons with one double bond are called alkenes.
http://purl.obolibrary.org/obo/UPa_UPA00353	carbohydrate sulfation	http://purl.obolibrary.org/obo/UPa_UPA00516	protein maturation		Sulfation is a critical modification in many instances of biological recognition.
http://purl.obolibrary.org/obo/UPa_UPA00354	eIF5A hypusination	http://purl.obolibrary.org/obo/UPa_UPA00516	protein maturation		Post-translational modification of archaea and eukaryotic translation initiation factor 5A (eIF5A), by covalent binding of hypusine to a lysine residue. Hypusine (N epsilon-(4-amino-2-hydroxybutyl)lysine) is a polyamine-derived amino-acid. The biosynthesis of hypusine occurs posttranslationally by modification of a single lysine residue. Translation initiation factor 5A (eIF5A), highly conserved throughout eukaryotes and some archaea, is the only known cellular protein to contain the unique polyamine-derived amino-acid hypusine. The name hypusine reflects the composition of this amino-acid, a combination of hydroxyputrescine and lysine. The unique feature of the hypusine modification is the strict specificity of the enzymes toward its substrate protein, eIF5A. Hypusine is formed in a novel posttranslational modification that involves two enzymes, deoxyhypusine synthase (DHS) and deoxyhypusine hydroxylase (DOHH). [PMID:16452303; PMID:17476569].
http://purl.obolibrary.org/obo/UPa_UPA00361	D-allose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of D-allose, an all-cis hexose utilized by some bacteria (Aerobacter aerogenes, E. coli, etc). D-allose is converted into fructose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UPA00362	L-valine degradation	http://purl.obolibrary.org/obo/UPa_UPA00431	Branched-chain amino-acid degradation		Degradation of L-valine, one of the three main branched chain amino-acids (BCAAs), along with L-leucine and L-isoleucine. In plants, branched-chain amino-acids are synthesized in chloroplasts, whereas the degradation takes place in mitochondria.
http://purl.obolibrary.org/obo/UPa_UPA00363	L-leucine degradation	http://purl.obolibrary.org/obo/UPa_UPA00431	Branched-chain amino-acid degradation		Degradation of L-leucine, one of the three main branched chain amino-acids (BCAAs), along with L-valine and L-isoleucine. In plants, branched-chain amino-acids are synthesized in chloroplasts, whereas the degradation takes place in mitochondria.
http://purl.obolibrary.org/obo/UPa_UPA00364	L-isoleucine degradation	http://purl.obolibrary.org/obo/UPa_UPA00431	Branched-chain amino-acid degradation		Degradation of L-isoleucine, one of the three main branched chain amino-acids (BCAAs), along with L-valine and L-leucine. In plants, branched-chain amino-acids are synthesized in chloroplasts, whereas the degradation takes place in mitochondria.
http://purl.obolibrary.org/obo/UPa_UPA00366	thiocyanate degradation	http://purl.obolibrary.org/obo/UPa_UPA00522	organosulfur degradation		Degradation of thiocyanate to carbonyl sulfide and ammonia.
http://purl.obolibrary.org/obo/UPa_UPA00367	testosterone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00440	steroid hormone biosynthesis		Biosynthesis of testosterone, a steroid hormone from the androgen group. Testosterone is primarily secreted in the testes of males and the ovaries of females although small amounts are secreted by the adrenal glands.
http://purl.obolibrary.org/obo/UPa_UPA00368	ethylene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00305	alkene biosynthesis		Biosynthesis of ethylene, an unsaturated hydrocarbon that contains one double bond (the simplest alkene). It acts as hormon in plant where it is essential for proper development, growth and survival. It is responsible for signaling changes during germination, flower and fruit development, the onset of plant defense responses, and cross-talk with other plant hormones.
http://purl.obolibrary.org/obo/UPa_UPA00369	tabtoxinine-beta-lactam biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00477	phytotoxin biosynthesis		Biosynthesis of tabtoxinine-beta-lactam, an irreversible inhibitor of glutamine synthetase produced by several pathovars of Pseudomonas syringae.
http://purl.obolibrary.org/obo/UPa_UPA00370	sulfite reduction	http://purl.obolibrary.org/obo/UPa_UPA00096	sulfur metabolism		Sulfite reduction aims at producing hydrogen sulfide from sulfite.
http://purl.obolibrary.org/obo/UPa_UPA00373	pinosylvin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00422	stilbenoid biosynthesis		Biosynthesis of pinosylvin, a pre-infectious stilbenoid toxin. Pinosylvin is synthesized prior to infection, contrary to phytoalexins which are synthesized during infection. It is present in the heart-wood of Pineceal. It is a fungitoxin protecting the wood from fungal infection.
http://purl.obolibrary.org/obo/UPa_UPA00374	hydropinosylvin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00422	stilbenoid biosynthesis		Dihydropinosylvin biosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00375	wybutosine-tRNA(Phe) biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00482	tRNA post-transcriptional modification		Biosynthesis of wybutosine (yW), a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic and archaeal phenylalanine tRNA.
http://purl.obolibrary.org/obo/UPa_UPA00376	auxin conjugation	http://purl.obolibrary.org/obo/UPa_UPA00887	auxin metabolism		Conjugation of auxin (indole-3-acetic acid, IAA) to many kinds of molecules is part of a regulatory mechanism for controlling IAA levels through sequestration and reuse, or as an entry into catabolism. IAA in plants occurs in both conjugated and free forms, and there is increasing evidence that the ratio of free to conjugated IAA is controlled by tissue-specific and developmentally regulated processes. The use of conjugation by plants to regulate IAA levels appears to have become increasingly more important as plants evolved from liverworts to mosses and tracheophytes.
http://purl.obolibrary.org/obo/UPa_UPA00377	sterigmatocystin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00478	mycotoxin biosynthesis		Biosynthesis of sterigmatocystin (ST), a carcinogenic mycotoxin. Sterigmatocystin is among the most toxic, mutagenic, and carcinogenic natural products known. This polyketide-derived secondary metabolite is produced by numerous fungi species.
http://purl.obolibrary.org/obo/UPa_UPA00378	protein glycosylation	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Protein glycosylation (the addition of saccharides to proteins) is one of the principal post-translational modification steps in the synthesis of membrane and secreted proteins. It is an enzyme-directed site-specific process, as opposed to the non-enzymatic chemical reaction of glycation. Two types of glycosylation exist: * N-linked glycosylation to the amide nitrogen of asparagine side chains * O-linked glycosylation to the hydroxy oxygen of serine and threonine side chains.
http://purl.obolibrary.org/obo/UPa_UPA00380	D-arabinitol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of D-arabinitol, an acyclic pentitol. Candida albicans produces large amount of D-arabinitol, but the biosynthetic pathway is not yet known.
http://purl.obolibrary.org/obo/UPa_UPA00381	brassinosteroid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00440	steroid hormone biosynthesis		Biosynthesis of brassinosteroids (brassins), a group of plant hormones, also called plant growth regulators. The most known example of brassinosteroids is brassinolide.
http://purl.obolibrary.org/obo/UPa_UPA00382	oxylipin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00199	fatty acid metabolism		Biosynthesis of oxylipins, a group of acyclic (or cyclic) oxidation products derived from the catabolism of fatty acids. Oxylipins regulate many defense and developmental pathways in plants.
http://purl.obolibrary.org/obo/UPa_UPA00383	arachidonate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00199	fatty acid metabolism		Metabolism of arachidonic acid, an omega-6 fatty acid (a carboxylic acid with a 20-carbon chain and four cis double bonds, the first double bond is located at the sixth carbon from the omega end). Arachidonic acid is a polyunsaturated fatty acid that is present in the phospholipids (especially phosphatidylethanolamine, phosphatidylcholine and phosphatidylinositides) of membranes of the body's cells. It is also involved in cellular signaling as a second messenger.
http://purl.obolibrary.org/obo/UPa_UPA00385	ethylene biosynthesis via 2-oxoglutarate	http://purl.obolibrary.org/obo/UPa_UPA00368	ethylene biosynthesis		Biosynthesis of ethylene via 2-oxoglutarate pathway. Bacterial ethylene-forming enzyme (EFE) catalyzes oxygenation of 2-oxoglutarate to produce ethylene and carbon dioxide in contrast to a plant enzyme which uses 1-aminocyclopropane-1-carboxylic acid as a substrate.
http://purl.obolibrary.org/obo/UPa_UPA00386	carotenoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of carotenoids, a group of essential photoprotective and antioxidant pigments that are naturally occurring in plants and some other photosynthetic organisms like algae, some types of fungus and some bacteria. There are over 600 known carotenoids; they are split into two classes, xanthophylls and carotenes. The most important function of carotenoid pigments, especially beta-carotene in higher plants, is to protect organisms against photooxidative damage. Carotenoid biosynthesis involves a series of desaturations, cyclizations, hydroxylations and epoxydations commencing with the formation of phytoene.
http://purl.obolibrary.org/obo/UPa_UPA00387	astaxanthin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis		Biosynthesis of astaxanthin, an abundant carotenoid found in marine animals, including salmonids and crustaceans. Astaxanthin has interest not only as a pigmentation source but also as a potent antioxidative reagent that can delay aging and the onset of degenerative diseases in animals.
http://purl.obolibrary.org/obo/UPa_UPA00388	neoxanthin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis		Biosynthesis of neoxanthin, an allenic xantophyll carotenoid thought to have two key roles as part of LHC's (light-harvesting complexes) and as a precursor to the plant growth hormone abscisic acid (ABA). Neoxanthin is recognized as the last product of carotenoid synthesis in green plants.
http://purl.obolibrary.org/obo/UPa_UPA00390	gibberellin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00438	plant hormone biosynthesis		Biosynthesis of gibberellins (GAs), a large family of plant growth substances with distinct functions during the whole life cycle of higher plants. Gibberellins are involved in promotion of stem elongation, mobilization of food reserves in seeds and other processes. Gibberellin was first isolated as a superelongation-promoting diterpenoid from the fungus, Gibberella fujikuroi. G. fujikuroi uses different GA biosynthetic intermediates from those in plants.
http://purl.obolibrary.org/obo/UPa_UPA00391	7-cyano-7-deazaguanine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00524	purine base biosynthesis		Biosynthesis of 7-cyano-7-deazaguanine (preQ0), a 7-deazapurine derivative, precursor of queuosine and archaeosine.
http://purl.obolibrary.org/obo/UPa_UPA00392	tRNA-queuosine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification		In most eubacterial and eukaryotic organisms the genetically encoded guanosine in the anticodon wobble position 34 of tRNA(His), tRNA(Tyr), tRNA(Asp) and tRNA(Asn) is replaced by the hypermodified nucleoside queuosine. The biosynthesis of queuosine commences outside of any tRNA with GTP which is converted to preQ0 (7-cyano-7-deazaguanine) in a poorly characterized pathway. Compound preQ0 is a precursor of archaeosine too. Hence, its biosynthesis is described in an independant pathway. The cyano group of preQ0 is reduced to a primary amine resulting in the formation of preQ1 (queuine). The purine scaffold of queuosine is replaced by a 7-deazapurine substituted with a dihydroxycyclopentenyl-aminomethyl moiety 7-aminomethyl-7-carbaguanine). Although no clearly defined function of queuosine has been established yet, Grimm et al [PMID:17083917] suggests a role in fine tuning of translational fidelity and speed.
http://purl.obolibrary.org/obo/UPa_UPA00393	archaeosine-tRNA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification		Biosynthesis of archaeosine, an archaea-specific modified base. Archaeosine (7-formamidino-7-deazaguanosine) is a structural variant of the hypermodified nucleoside 7-deazaguanosine. The biosynthesis pathway starts with archaeosine tRNA-guanine transglycosylase (ArcTGT) which catalyzes the exchange of guanine at position 15 in the D-loop of archaeal tRNAs with a free 7-cyano-7-deazaguanine (preQ(0)) base.
http://purl.obolibrary.org/obo/UPa_UPA00396	aminophosphonate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of aminophosphonates, amino-acid derivatives that contain a phosphonic acid moiety (C-PO(OH)2 or C-PO(OR)2).
http://purl.obolibrary.org/obo/UPa_UPA00397	aminophosphonate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00960	phosphonate biosynthesis		Biosynthesis of aminophosphonates, amino-acid derivatives that contain a phosphonic acid moiety (C-PO(OH)2 or C-PO(OR)2).
http://purl.obolibrary.org/obo/UPa_UPA00398	cofactor metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		The chemical reactions and physical changes of a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00398	cofactor metabolism		The formation from simpler components of a cofactor, a non-protein chemical substance that is tightly bound to an enzyme and is required for catalysis. Cofactors can be considered 'helper molecules/ions' that assist in biochemical transformations. Coenzyme biosynthesis pathways, e.g coenzyme A biosynthesis are considered under this pathway-category.
http://purl.obolibrary.org/obo/UPa_UPA00400	purine base metabolism	http://purl.obolibrary.org/obo/UPa_UPA00523	heterocycle metabolism		Metabolism of purine, a heterocyclic aromatic organic compound consisting of a pyrimidine ring fused to an imidazole ring. Purines make up one of the two groups of nitrogenous bases, Pyrimidines make up the other group. These bases make up a crucial part of both deoxyribonucleotides and ribonucleotides, and the basis for the universal genetic code. The general term purines also refers to substituted purines and their tautomers.
http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		metabolism of amino-acids, a group of organic compound containing an amino group (NH2), a carboxylic acid group (COOH), and any of various side groups, especially any of the 20 compounds that have the basic formula NH2CHRCOOH, and that link together by peptide bonds to form proteins or that function as chemical messengers and as intermediates in metabolism. Amino-acids are the precursors of many molecules such as purines, pyrimidines, histamines, adrenaline and melanin.
http://purl.obolibrary.org/obo/UPa_UPA00402	amino-acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		The formation from simpler components of amino-acids, organic acids containing one or more amino substituents.
http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00402	amino-acid biosynthesis		The chemical reactions and pathways resulting in the formation of any amino-acid that normally occur as a constituent residue of proteins [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00404	L-lysine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		This pathway represents the biosynthesis of the basic amino-acid L-lysine. L-lysine biosynthesis is peculiar because it has two different anabolic routes that evolved separately in organisms, the diaminopimelate (DAP) and aminoadipate (AAA) pathways. The DAP pathway synthesizes L-lysine from aspartate and pyruvate, and diaminopimelate is an intermediate. The DAP pathway is utilised by most bacteria, some archaea, some fungi, some algae, and plants. The AAA pathway synthesizes L-lysine from 2-oxoglutarate (alpha-ketoglutarate) and acetyl coenzyme A (acetyl-CoA), and L-alpha-aminoadipate is an intermediate. The AAA pathway is utilised by most fungi, some algae, the bacterium Thermus thermophilus, and probably some archaea, such as Sulfolobus, Thermoproteus, and Pyrococcus [source: InterPro]. No organism is known to possess both pathways [PMID:20418392]. L-lysine is one of the 10 essential amino-acids that mammals are unable to synthesize, and must therefore acquire in their diets.
http://purl.obolibrary.org/obo/UPa_UPA00405	myo-inositol degradation	http://purl.obolibrary.org/obo/UPa_UPA00614	polyol degradation		degradation of myo-inositol, one of nine distinct isomers of inositol.
http://purl.obolibrary.org/obo/UPa_UPA00406	nonprotein amino-acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00402	amino-acid biosynthesis		The chemical reactions and pathways resulting in the formation of any amino-acid that does not normally occur as a constituent residue of proteins [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00407	ureide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00045	nitrogen metabolism		The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00408	ketone metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The chemical reactions and physical changes involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
http://purl.obolibrary.org/obo/UPa_UPA00409	ketone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00408	ketone metabolism		The formation from simpler components of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
http://purl.obolibrary.org/obo/UPa_UPA00410	ketone degradation	http://purl.obolibrary.org/obo/UPa_UPA00408	ketone metabolism		The degradation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of carbohydrates. Carbohydrates are essential structural component of living cells and source of energy. They include simple sugars with small molecules as well as macromolecular substances. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y. Carbohydrates are classified according to the number of monosaccharide groups they contain.
http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		The formation from simpler components of carbohydrates. Carbohydrates are essential structural component of living cells and source of energy. They include simple sugars with small molecules as well as macromolecular substances. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y. Carbohydrates are classified according to the number of monosaccharide groups they contain.
http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		The degradation into simpler components of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
http://purl.obolibrary.org/obo/UPa_UPA00414	alkaloid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00045	nitrogen metabolism		Metabolism of alkaloids, a group of nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino-acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases). Alkaloids are usually found in plants. Various alkaloids have toxic or medical properties, such as caffeine, morphine and nicotine.
http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		The formation from simpler components of compounds acting as metabolic intermediates.
http://purl.obolibrary.org/obo/UPa_UPA00416	isoprenoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00913	isoprenoid metabolism		The formation from simpler components of isoprene derivatives. Isoprene is the chemical 2-methyl-1,3-butadiene. It is a common structural motif in biological systems. The terpenes (for example, the carotenes are tetraterpenes) are derived from isoprene, as are the terpenoids and coenzyme Q. Also derived from isoprene are phytol, retinol (vitamin A) , tocopherol (vitamin E), dolichols, and squalene. Heme A has an isoprenoid tail, and lanosterol, the sterol precursor in animals, is derived from squalene and hence from isoprene. The functional isoprene units in biological systems are dimethylallyl pyrophosphate (DMAPP) and its isomer isopentenyl pyrophosphate (IPP), which are used in the biosynthesis of terpenes and lanosterol derivatives.
http://purl.obolibrary.org/obo/UPa_UPA00417	isopentenyl diphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00416	isoprenoid biosynthesis		Biosynthesis of isopentenyl-PP (isopentenyl diphosphate, IPP), the central intermediate in the biosynthesis of terpenoids (isoprenoids) Despite their diversity, all isoprenoids are derived from two universal five-carbon precursors: isopentenyl diphosphate (IPP) and its isomer dimethylallyl diphosphate (DMAPP). Two distinct routes of IPP biosynthesis occur in nature: the 'mevalonate pathway' and the recently discovered 'deoxyxylulose 5-phosphate (DXP) pathway'.
http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00386	carotenoid biosynthesis		Biosynthesis of carotene compounds, i.e carotenoids that do not contain oxygen.
http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00386	carotenoid biosynthesis		Biosynthesis of xanthophylls (originally phylloxanthins), yellow pigments (oxycarotenoid type) from the carotenoid group.
http://purl.obolibrary.org/obo/UPa_UPA00420	lipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		The formation from simpler components of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
http://purl.obolibrary.org/obo/UPa_UPA00421	phytoalexin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00479	antifungal biosynthesis		Biosynthesis of phytoalexins, a group of antibiotics produced by plants that are under attack. Phytoalexins tend to fall into several classes including terpenoids, glycosteroids and alkaloids. It is convenient to extend the definition to include all phytochemicals that are part of the plant's defensive arsenal. Phytoalexins produced in plants act as toxins to the attacking organism.
http://purl.obolibrary.org/obo/UPa_UPA00422	stilbenoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of stilbenoids. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Chemically they are hydroxylated derivatives of stilbene.
http://purl.obolibrary.org/obo/UPa_UPA00423	terpene metabolism	http://purl.obolibrary.org/obo/UPa_UPA00325	hydrocarbon metabolism		Metabolism of terpenes, a class of hydrocarbons produced by many plants, particularly conifers. Terpenes are major components of resin, and of turpentine produced from resin. The name 'terpene' comes from 'turpentine'. Terpenes are derived from isoprene C5H8 units and have the basic formula of multiples of it, i.e., (C5H8)n. The isoprene units can be arranged in a linear way or forming rings. One can consider isoprene as one of nature's preferred building blocks. Terpenes can be classified according to the number of isoprene units that they contain: * Monoterpenes, C10H16, 2 isoprene units * Sesquiterpenes, C15H24, 3 isoprene units * Diterpenes, C20H32, 4 isoprene units * Triterpenes, C30H48, 6 isoprene units * Tetraterpenes, C40H60, 8 isoprene units * Polyterpenes with a large number of isoprene units If terpenes are further modified, for instance by adding hydroxyl groups or moving or removing a methyl group, the resulting compounds are called terpenoids. (Some authors also call these compounds terpenes.) [wikipedia].
http://purl.obolibrary.org/obo/UPa_UPA00424	nucleotide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The formation from simpler components of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
http://purl.obolibrary.org/obo/UPa_UPA00425	nucleoside biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of nucleosides. Nucleosides are glycosylamines made by attaching a nucleobase (often referred to simply as bases) to a ribose or deoxyribose ring. In short, a nucleoside is a base linked to sugar.
http://purl.obolibrary.org/obo/UPa_UPA00426	energy metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The chemical reactions involved in energy transformations within cells.
http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		The breakdown into simpler components of amino-acids, organic acids containing one or more amino substituents.
http://purl.obolibrary.org/obo/UPa_UPA00428	lipid degradation	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Degradtion of lipids.
http://purl.obolibrary.org/obo/UPa_UPA00429	L-arginine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		Metabolism of L-arginine, one of the 20 most common natural amino-acids.
http://purl.obolibrary.org/obo/UPa_UPA00430	fatty acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00428	lipid degradation		Degradation of fatty acids.
http://purl.obolibrary.org/obo/UPa_UPA00431	Branched-chain amino-acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of the branched-chain amino-acids leucine (Leu), isoleucine (Ile) and valine (Val).
http://purl.obolibrary.org/obo/UPa_UPA00432	plant chemical defense	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		production of chemical defenses such as toxins against herbivores.
http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of aromatic compounds.
http://purl.obolibrary.org/obo/UPa_UPA00434	hormone metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of hormone, a chemical messenger from one cell (or group of cells) to another. All multicellular organisms produce hormones (including plants, i.e phytohormone). The function of hormones is to serve as a signal to the target cells; the action of hormones is determined by the pattern of secretion and the signal transduction of the receiving tissue.
http://purl.obolibrary.org/obo/UPa_UPA00435	hormone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00434	hormone metabolism		Biosynthesis of hormone, a chemical messenger from one cell (or group of cells) to another. Plant hormones pathways are described as phytohormone biosynthesis pathways.
http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of lipid compounds.
http://purl.obolibrary.org/obo/UPa_UPA00437	plant hormone metabolism	http://purl.obolibrary.org/obo/UPa_UPA00434	hormone metabolism		Metabolism of plant hormones (plant growth regulators, PGRs, phytohormones). Plant hormones are internally-secreted chemicals in plants that are used for regulating the plant growth. According to a standard definition, plant hormones are signal molecules produced at specific locations, that occur in very low concentrations, and cause altered processes in target cells at other locations. It is accepted that there are five major classes of plant hormones: auxins, cytokinins(CK's), ethylene, gibberellins (GA's) and abscisic acid (ABA).
http://purl.obolibrary.org/obo/UPa_UPA00438	plant hormone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00437	plant hormone metabolism		Biosynthesis of plant hormones (plant growth regulators, PGRs, phytohormones).
http://purl.obolibrary.org/obo/UPa_UPA00439	plant hormone degradation	http://purl.obolibrary.org/obo/UPa_UPA00437	plant hormone metabolism		degradation of plant hormones (plant growth regulators, PGRs, phytohormones).
http://purl.obolibrary.org/obo/UPa_UPA00440	steroid hormone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00435	hormone biosynthesis		Biosynthesis of steroid hormones.
http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of glycan polymers. The term glycan refers to a polysaccharide, or oligosaccharide. Glycan may also be used to refer to the carbohydrate portion of a glycoconjugate, such as a glycoprotein, glycolipid, or a proteoglycan.
http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Degradation of glycan polymers. The term glycan refers to a polysaccharide, or oligosaccharide. Glycan may also be used to refer to the carbohydrate portion of a glycoconjugate, such as a glycoprotein, glycolipid, or a proteoglycan.
http://purl.obolibrary.org/obo/UPa_UPA00443	trehalose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Metabolism of trehalose (mycose), a disaccharide found extensively but not abundantly in nature. It can be synthesised by fungi, plants and invertebrate animals. It is implicated in anhydrobiosis - the ability of plants and animals to withstand prolonged periods of desiccation. Trehalose is the major carbohydrate energy storage molecule used by insects for flight.
http://purl.obolibrary.org/obo/UPa_UPA00444	glucan metabolism	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Metabolism of glucans, a group of polysaccharides of D-glucose monomers linked by glycosidic bonds.
http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolic pathways related to the flow of one-carbon units into cellular compounds.
http://purl.obolibrary.org/obo/UPa_UPA00446	alkaloid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases). [GO].
http://purl.obolibrary.org/obo/UPa_UPA00447	alkaloid degradation	http://purl.obolibrary.org/obo/UPa_UPA00414	alkaloid metabolism		Degradation of alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00448	terpene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00423	terpene metabolism		The formation from simpler components of terpenes.
http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00448	terpene biosynthesis		The formation from simpler components of sesquiterpenes. Sesquiterpenes are a class of terpenes that consist of three isoprene units and have the molecular formula C15H24. Like monoterpenes, sesquiterpenes may be acyclic or contain rings, including many unique combinations. Biochemical modifications such as oxidation or rearrangement produce the related sesquiterpenoids.
http://purl.obolibrary.org/obo/UPa_UPA00450	activated methyl cycle	http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism		The activated methyl donor involved in most biosynthetic methylation is usually S-adenosylmethionine (SAM). SAM is synthesized by the transfer of an adenosyl group from ATP to the sulfur atom of methionine. The methyl group of the methionine unit is activated by the positive charge on the adjacent sulfur atom, which makes the molecule much more reactive than N5-methyltetrahydrofolate. The synthesis of S-adenosylmethionine is unusual in that the triphosphate group of ATP is split into pyrophosphate and orthophosphate; the pyrophosphate is subsequently hydrolyzed to two molecules of Pi. S-Adenosylhomocysteine is formed when the methyl group of S-adenosylmethionine is transferred to an acceptor. S-Adenosylhomocysteine is then hydrolyzed to homocysteine and adenosine. Methionine can be regenerated by the transfer of a methyl group to homocysteine. [Stryer, Biochemistry, 2002].
http://purl.obolibrary.org/obo/UPa_UPA00451	lipopolysaccharide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00316	biopolymer metabolism		The chemical reactions involving lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
http://purl.obolibrary.org/obo/UPa_UPA00452	lipopolysaccharide degradation	http://purl.obolibrary.org/obo/UPa_UPA00451	lipopolysaccharide metabolism		Degradation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane.
http://purl.obolibrary.org/obo/UPa_UPA00453	GDP-L-fucose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of GDP-L-fucose from GDP-D-mannose. GDP-L-fucose is the substrate of fucosyltransferases for addition of fucose to polysaccharides or glycoproteins in both procaryotes and eucaryotes. In mammals, the biosynthesis of GDP-L-fucose consists of two pathways, namely salvage and de novo pathways.
http://purl.obolibrary.org/obo/UPa_UPA00454	oligopeptide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of oligopeptides.
http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of amines and polyamines. These compounds play a variety of roles in metabolism, including acting as osmoprotectants, keeping DNA in a condensed state, and serving as intermediates in the synthesis of macromolecules. The polyamines, e.g. 1,3-diaminopropane, putrescine, cadaverine, agmatine, spermidine and spermine, are wide-spread in all organisms, and have been shown to play a role in the regulation of growth and differentiation of virtually all types of cells.
http://purl.obolibrary.org/obo/UPa_UPA00456	amine and polyamine degradation	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Degradation of amines and polyamines.
http://purl.obolibrary.org/obo/UPa_UPA00457	putrescine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Metabolism of putrescine, 1,4-diaminobutane. Putrescine is one of polyamines that are found in a wide range of organisms from bacteria to plants and animals, especially when these cells are proliferating or under stressful conditions (Tabor & Tabor, 1984). Polyamines can modulate the functions of RNA, DNA, nucleotide triphosphates, proteins, and other acidic substances, and they contribute to stimulate cell growth and viability (Igarashi & Kashiwagi, 2000). Putrescine is the metabolic precursor of spermidine and spermine.
http://purl.obolibrary.org/obo/UPa_UPA00458	protein biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00467	protein metabolism		Biosynthesis of proteins.
http://purl.obolibrary.org/obo/UPa_UPA00459	pheromone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of pheromones. A pheromone is a chemical that triggers an innate behavioural response in another member of the same species. There are alarm pheromones, food trail pheromones, sex pheromones, and many others that affect behavior or physiology.
http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification	http://purl.obolibrary.org/obo/UPa_UPA00467	protein metabolism		Proteins are subjected to three classes of protein modifications, i.e. pre-, co- and post-translational modifications. A majority of modifications are made when the protein is already folded; these are genuine post-translational modifications (PTMs). Some modifications are made while the polypeptide is still being synthesized on the ribosome; these are co-translational modifications. A few 'non-standard' amino-acids are incorporated into proteins by modification of some 'standard' amino-acids while they are charged on special tRNAs; these are pre-translational modifications.
http://purl.obolibrary.org/obo/UPa_UPA00461	post-translational protein modification	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Post-translation modifications are defined as 'series of chemical reactions whereby a newly synthesized polypeptide chain is converted to a functional protein. At the genetic point of view, any difference between a functional protein and the linear polypeptide sequence encoded between the initiation and the termination codons of its structural gene can be regarded as a post-translational modification of proteins. [This definition] restricts the meaning of post-translational modification to modifications that involve the making or breaking of covalent bonds.' (Han K.-K., Martinage A., 1992).
http://purl.obolibrary.org/obo/UPa_UPA00462	small protein conjugation	http://purl.obolibrary.org/obo/UPa_UPA00461	post-translational protein modification		Protein modification by small protein conjugation is a process by which one or more moieties of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00463	L-arabinose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of L-arabinose Degradation of L-arabinose, a major constituent of plant material. Bacteria and fungi can utilize this pentose sugar via different pathways. Two distinct pathways convert L-arabinose to D-xylulose 5-phosphate via L-ribulose (in bacteria) or via L-arabitol (in fungal). An additional pathway has been recently discovered in bacteria (A. brasiliense, H. seropedicae, P. saccharophila, S. meliloti). In this pathway, L-arabinose is oxidized to L-arabino-gamma-lactone.
http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00465	secondary metabolite metabolism		The formation from simpler components of secondary metabolites.
http://purl.obolibrary.org/obo/UPa_UPA00465	secondary metabolite metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of secondary metabolites. Secondary metabolites are those chemical compounds in organisms that are not directly involved in the normal growth, development or reproduction of organisms. Typically primary metabolites are found across all species within broad phylogenetic groupings, and are produced using the same pathway (or nearly the same pathway) in all these species. Secondary metabolites, by contrast, are often species- specific (or found in only a small set of species in a narrow phylogenetic group), and without these compounds the organism suffers from only a mild impairment, lowered survivability/fecundity, aesthetic differences, or else no change in phenotype at all [http://en.wikipedia.org/wiki/Secondary_metabolite].
http://purl.obolibrary.org/obo/UPa_UPA00466	biopolymer degradation	http://purl.obolibrary.org/obo/UPa_UPA00316	biopolymer metabolism		The chemical reactions and pathways resulting in the breakdown of biopolymers, long, repeating chains of monomers found in nature e.g. polysaccharides and proteins [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00467	protein metabolism	http://purl.obolibrary.org/obo/UPa_UPA00316	biopolymer metabolism		Metabolic pathways involving a specific protein as substrate.
http://purl.obolibrary.org/obo/UPa_UPA00468	protein degradation	http://purl.obolibrary.org/obo/UPa_UPA00467	protein metabolism		Degradation of cellular proteins.
http://purl.obolibrary.org/obo/UPa_UPA00469	lincosamide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of lincosamide group of antibiotics.
http://purl.obolibrary.org/obo/UPa_UPA00470	lantibiotic biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of lantibiotics, a group of antimicrobial peptides synthesized by Gram- positive bacteria. Due to their difference in structure, two types of lantibiotics are distinguished, type A and type B lantibiotics.
http://purl.obolibrary.org/obo/UPa_UPA00471	lantibiotic A biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00470	lantibiotic biosynthesis		Biosynthesis of lantibiotics A. Type A lantibiotics are elongated, flexible peptides that act by forming pores in bacterial membrane.
http://purl.obolibrary.org/obo/UPa_UPA00472	lantibiotic B biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00470	lantibiotic biosynthesis		Biosynthesis of lantibiotics B. Type B lantibiotics are rigid, globular peptides with no net charge or a negative net charge. The type B comprise mersacidin, actagardin, and the cinnamycin group of peptides.
http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of polyketides, a large group of complex natural products produced mainly by species of Streptomyces and related filamentous bacteria that include antibacterial, antifungal, anticancer, antiparasitic and immunosuppressant compounds. Despite their structures being strikingly diverse, they share a common pattern of biosynthesis in which simple carboxylic acid units are condensed onto the growing chain by a polyketide synthase (PKS) in a process resembling fatty acid biosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00474	penicillin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00169	beta-lactam biosynthesis		Biosynthesis of penicillin (sometimes abbreviated PCN), a group of beta- lactam antibiotics used in the treatment of bacterial infections caused by susceptible, usually Gram-positive, organisms.
http://purl.obolibrary.org/obo/UPa_UPA00475	cephalosporin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00169	beta-lactam biosynthesis		Biosynthesis of cephalosporins, a class of beta-lactam antibiotics. Together with cephamycins they belong to a sub-group called cephems. Cephalosporins are bactericidal and have the same mode of action as other beta-lactam antibiotics (such as penicillins). Cephalosporins disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The final transpeptidation step in the synthesis of the peptidoglycan is facilitated by transpeptidases known as penicillin binding proteins (PBPs).
http://purl.obolibrary.org/obo/UPa_UPA00476	toxin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of toxins.
http://purl.obolibrary.org/obo/UPa_UPA00477	phytotoxin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00476	toxin biosynthesis		Biosynthesis of phytotoxins.
http://purl.obolibrary.org/obo/UPa_UPA00478	mycotoxin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00476	toxin biosynthesis		Biosynthesis of mycotoxins, a group of toxins produced by fungus (mushrooms, molds and yeasts).
http://purl.obolibrary.org/obo/UPa_UPA00479	antifungal biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of antifungal compounds.
http://purl.obolibrary.org/obo/UPa_UPA00480	RNA modification	http://purl.obolibrary.org/obo/UPa_UPA00123	biopolymer modification		RNA modification processes.
http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification	http://purl.obolibrary.org/obo/UPa_UPA00480	RNA modification		The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically [source: GO]. Transfer RNA (tRNA) is structurally unique among nucleic acids in harboring an astonishing diversity of post-transcriptionally modified nucleoside. Over 80 modified nucleosides have been characterized. The nature of nucleoside modification varies from simple methylation to extensive 'hypermodification' of the canonical bases. Two of the most radically modified nucleosides known to occur in tRNA are queuosine and archaeosine, both of which are characterized by a 7-deazaguanosine core structure.
http://purl.obolibrary.org/obo/UPa_UPA00482	tRNA post-transcriptional modification	http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification		Post-transcriptional modification of tRNA molecules.
http://purl.obolibrary.org/obo/UPa_UPA00483	cofactor degradation	http://purl.obolibrary.org/obo/UPa_UPA00398	cofactor metabolism		Pathways involved in the degradation of cofactors.
http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Biosynthesis of glycan (polysaccharide) polymers. Glycan may also be used to refer to the carbohydrate portion of a glycoconjugate, such as a glycoprotein or a proteoglycan. Glycans usually consist solely of O-glycosidic linkages of monosaccharides (cellulose is a glycan composed of beta-1,4-linked D-glucose; chitin is a glycan composed of beta-1,4-linked N-acetyl-D-glucosamine). Glycans can be homo or heteropolymers of monosaccharide residues, and can be linear or branched.
http://purl.obolibrary.org/obo/UPa_UPA00485	genetic information processing	http://purl.obolibrary.org/obo/UPa_UPA00001	biological process		Processing of genetic information.
http://purl.obolibrary.org/obo/UPa_UPA00486	nucleotide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of nucleotides.
http://purl.obolibrary.org/obo/UPa_UPA00487	polyester biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of polyester, a category of polymers which contain the ester functional group in their main chain.
http://purl.obolibrary.org/obo/UPa_UPA00488	purine nucleotide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00584	purine biosynthesis		The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00489	alanine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		Metabolism of (DL)-alanine, one of the major amino-acids present in proteins. Alanine can be used in the biosynthesis of the amino-acid valine and of the vitamin biotin, and both the L and D stereoisomers of alanine are major constituents of the peptidoglycan layer.
http://purl.obolibrary.org/obo/UPa_UPA00490	histidine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		Metabolism of (DL)-histidine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00491	alanine degradation	http://purl.obolibrary.org/obo/UPa_UPA00489	alanine metabolism		Degradation of (DL)-alanine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00492	L-histidine degradation	http://purl.obolibrary.org/obo/UPa_UPA00490	histidine metabolism		Degradation of L-histidine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00493	L-threonine degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of L-threonine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00494	glycerolipid degradation	http://purl.obolibrary.org/obo/UPa_UPA00230	glycerolipid metabolism		Degradation of glycerolipids.
http://purl.obolibrary.org/obo/UPa_UPA00495	glycerolipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00420	lipid biosynthesis		Biosynthesis of glycerolipids.
http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of metabolic intermediate compounds.
http://purl.obolibrary.org/obo/UPa_UPA00497	(R)-mevalonate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of (R)-mevalonate, a key organic compound in biochemistry. (R)-mevalonate is a precursor of terpenes and steroids.
http://purl.obolibrary.org/obo/UPa_UPA00498	metabolic intermediate degradation	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Degradation of metabolic intermediate compounds.
http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00672	pigment metabolism		Biosynthesis of pigments.
http://purl.obolibrary.org/obo/UPa_UPA00500	Lipooligosaccharide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Metabolism of lipooligosaccharide.
http://purl.obolibrary.org/obo/UPa_UPA00501	lipooligosaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00938	membrane lipid biosynthesis		Biosynthesis of lipooligosaccharide (LOS), an important amphiphilic molecule integrated in and extending outward from the outer membrane of some bacterial cell wall (Neisseria and Haemophilus sp). LOS is similar to lipopolysaccharide (LPS) but lacking the O-antigen polysaccharide side chain repeats. LOS comprises two parts: i) core oligosaccharide and ii) lipid A.
http://purl.obolibrary.org/obo/UPa_UPA00502	alginate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Metabolism of alginate, a polyssacharide produced by brown seaweeds an some bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00503	choline metabolism	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Metabolism of choline (bilineurine).
http://purl.obolibrary.org/obo/UPa_UPA00504	steroid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Metabolism of steroids. A steroid is a terpenoid lipid characterized by a carbon skeleton with four fused rings, derived from the cyclization of the triterpene squalene. Different steroids vary in the functional groups attached to these rings.
http://purl.obolibrary.org/obo/UPa_UPA00505	glycolipid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid.
http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00505	glycolipid metabolism		Biosynthesis of glycolipids (e.g glycosylphosphatidylinositol).
http://purl.obolibrary.org/obo/UPa_UPA00507	tropane alkaloid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00414	alkaloid metabolism		The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00508	tropane alkaloid degradation	http://purl.obolibrary.org/obo/UPa_UPA00507	tropane alkaloid metabolism		Degradation of tropan alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00509	isoquinoline alkaloid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00414	alkaloid metabolism		Metabolism of isoquinoline alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00510	isoquinoline alkaloid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00509	isoquinoline alkaloid metabolism		Biosynthesis of isoquinoline alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00511	terpenoid indole alkaloid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00423	terpene metabolism		Metabolism of terpenoid indole alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00512	terpenoid indole alkaloid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00511	terpenoid indole alkaloid metabolism		Biosynthesis of terpenoid indole alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00513	pyrimidine nucleotide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis		Biosynthesis of pyrimidine nucleotides.
http://purl.obolibrary.org/obo/UPa_UPA00514	isoquinoline alkaloid degradation	http://purl.obolibrary.org/obo/UPa_UPA00509	isoquinoline alkaloid metabolism		Biosynthesis of isoquinoline alkaloids.
http://purl.obolibrary.org/obo/UPa_UPA00515	carbon fixation	http://purl.obolibrary.org/obo/UPa_UPA00091	photosynthesis		Carbon fixation is a process found in autotrophs, usually driven by photosynthesis, whereby carbon dioxide (CO(2)) is converted into organic compounds. There are three types of carbon fixation pathways: i) C3 acid cycle; ii) C4 acid cycle; iii) CAM pathway.
http://purl.obolibrary.org/obo/UPa_UPA00516	protein maturation	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Protein maturation process.
http://purl.obolibrary.org/obo/UPa_UPA00517	hydrogenase maturation	http://purl.obolibrary.org/obo/UPa_UPA00516	protein maturation		Protein maturation via an hydrogenase process.
http://purl.obolibrary.org/obo/UPa_UPA00518	hopanoid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00504	steroid metabolism		Metabolism of hopanoids, a group of pentacyclic compounds similar to sterols, whose primary function is to improve plasma membrane fluidity in prokaryotes. Cholesterol serves a similar function in eukaryotes (including humans).
http://purl.obolibrary.org/obo/UPa_UPA00519	hyaluronan metabolism	http://purl.obolibrary.org/obo/UPa_UPA00860	glycosaminoglycan metabolism		Metabolism of hyaluronan (hyaluronic acid), a glycosaminoglycan distributed widely throughout connective, epithelial, and neural tissues. It is one of the major components of the extracellular matrix and thereby contributes significantly to cell proliferation and migration. It may be involved in the progression of some malignant tumors.
http://purl.obolibrary.org/obo/UPa_UPA00520	organosulfur metabolism	http://purl.obolibrary.org/obo/UPa_UPA00096	sulfur metabolism		Metabolism of organosulfurs, organic compounds that contain sulfur.
http://purl.obolibrary.org/obo/UPa_UPA00521	organosulfur biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00520	organosulfur metabolism		Biosynthesis of organosulfurs, organic compounds that contain sulfur.
http://purl.obolibrary.org/obo/UPa_UPA00522	organosulfur degradation	http://purl.obolibrary.org/obo/UPa_UPA00520	organosulfur metabolism		Degradation of organosulfurs, organic compounds that contain sulfur.
http://purl.obolibrary.org/obo/UPa_UPA00523	heterocycle metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings) [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00524	purine base biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00584	purine biosynthesis		Biosynthesis of purine base, an heterocyclic aromatic organic compound found in DNA or RNA.
http://purl.obolibrary.org/obo/UPa_UPA00525	aromatic amino-acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of amino-acid with an aromatic side-chain: phenylalanine (Phe), tyrosine (Tyr) and tryptophan (Trp).
http://purl.obolibrary.org/obo/UPa_UPA00526	L-tryptophan degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of amino-acid L-tryptophan.
http://purl.obolibrary.org/obo/UPa_UPA00531	L-proline metabolism	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino-acid found in peptide linkage in proteins.
http://purl.obolibrary.org/obo/UPa_UPA00532	L-proline degradation	http://purl.obolibrary.org/obo/UPa_UPA00531	L-proline metabolism		Degradation of L-proline (pyrrolidine-2-carboxylic acid) amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00536	protein lipoylation	http://purl.obolibrary.org/obo/UPa_UPA00516	protein maturation		R-(+)-lipoic acid is a disulfide-containing cofactor widely distributed among living organisms. It is covalently attached to the E2 acyltransferase subunit of the pyruvate, alpha-ketoglutarate, and branched-chain alpha-ketoacid dehydrogenase complexes and to H-protein of the glycine cleavage system via an amide linkage between the carboxyl group of lipoic acid and the epsilon-amino group of a specific lysine residue of these proteins. Protein lipoylation can be achieved by two distinct pathways.
http://purl.obolibrary.org/obo/UPa_UPA00539	pyrroloquinoline quinone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00829	quinol/quinone biosynthesis		Biosynthesis of pyrroloquinoline quinone (PQQ, 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid), a bacterial vitamin that serves as a cofactor in numerous alcohol dehydrogenases. Its biosynthesis in Klebsiella pneumoniae is facilitated by six genes, pqqABCDEF, and proceeds by an unknown pathway.
http://purl.obolibrary.org/obo/UPa_UPA00544	peptidoglycan recycling	http://purl.obolibrary.org/obo/UPa_UPA00547	cell wall biogenesis		Recycling of peptidoglycan, also known as murein, a polymer consisting of sugars and amino-acids that forms a mesh-like layer outside the plasma membrane of eubacteria.
http://purl.obolibrary.org/obo/UPa_UPA00545	pectin degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
http://purl.obolibrary.org/obo/UPa_UPA00546	cell wall metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of cell wall components.
http://purl.obolibrary.org/obo/UPa_UPA00547	cell wall biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00931	cellular component biogenesis		Biosynthesis of cell wall components.
http://purl.obolibrary.org/obo/UPa_UPA00548	cell wall degradation	http://purl.obolibrary.org/obo/UPa_UPA00546	cell wall metabolism		Degradation of cell wall components.
http://purl.obolibrary.org/obo/UPa_UPA00549	peptidoglycan degradation	http://purl.obolibrary.org/obo/UPa_UPA00548	cell wall degradation		Degradation of peptidoglycan, also known as murein, a polymer consisting of sugars and amino-acids that forms a mesh-like layer outside the plasma membrane of eubacteria.
http://purl.obolibrary.org/obo/UPa_UPA00550	thermoadapter biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biosynthesis of thermoadapter, low molecular-weight compounds with thermoadaptive function (e.g cyclic 2,3-diphosphoglycerate).
http://purl.obolibrary.org/obo/UPa_UPA00552	cytidine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00313	pyrimidine nucleotide metabolism		Metabolism of cytidine, a pyrimidine deoxynucleoside.
http://purl.obolibrary.org/obo/UPa_UPA00553	fermentation	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Fermentation is the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, yielding energy in the form of adenosine triphosphate (ATP). [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00555	cytochrome c assembly	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Bacterial c-type cytochromes are localized to the outside of the cytoplasmic membrane where they function in electron transport processes. Assembly takes place on the outside of the cytoplasmic membrane, involving separate transport of heme and the apocytochrome across the membrane [PMID:2172694]; the latter occurs via the general protein secretory (Sec) pathway of the cell [PMID:9219541]. Following translocation, assembly proceeds via a pathway involving a number of specific proteins. Two distinct systems have been identified in bacteria. System I is found in alpha - and gamma -proteobacteria, including E. coli, R. capsulatus, B. japonicum, and P. denitrificans. System II seems more widespread than system I, occurring in a range of bacteria including cyanobacteria, Gram-positive bacteria such as Mycobacterium species, beta -, gamma -, and delta -proteobacteria such as B. pertussis, T. ferrooxidans, and H. pylori, respectively, and some extremophiles such as A. aeoliticus. Common to both systems is that the apocytochrome cysteine thiols and the heme iron must be in their reduced states for thioether bond formation to occur. Thiol-disulfide oxidoreductases are required for this, and specific proteins have been identified in a number of system I organisms, including E. coli (CcmG), R. capsulatus (HelX), B. japonicum (CycY), and P. denitrificans (CcmG), and one system II organism, B. pertussis (CcsX) [PMID:12637552].
http://purl.obolibrary.org/obo/UPa_UPA00556	lipoteichoic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00547	cell wall biogenesis		Biosynthesis of lipoteichoic acid (LTA), a glycerol phosphate surface polymer. Lipoteichoic acid is a component of the envelope of Gram-positive bacteria. This polyphosphoglycerol compound is substituted with a D-alanyl (D-Ala) ester or a glycosyl residue and is anchored in the membrane by its glycolipid moiety.
http://purl.obolibrary.org/obo/UPa_UPA00559	peptidyl-diphthamide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		The translation elongation factor 2 (eEF-2) in eukaryotes and some archaea contains a unique posttranslationally modified histidine residue, termed diphthamide, which serves as the only target for diphtheria toxin and Pseudomonas aeruginosa exotoxin A. The biosynthesis of diphthamide represents one of the most complex posttranslational modifications. The biosynthesis is accomplished by stepwise additions to the His715 (His699 in yeast) residue of eEF-2.
http://purl.obolibrary.org/obo/UPa_UPA00560	ethanolamine degradation	http://purl.obolibrary.org/obo/UPa_UPA00612	alcohol degradation		Degradation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
http://purl.obolibrary.org/obo/UPa_UPA00566	enterobacterial common antigen biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of enterobacterial common antigen (ECA), a cell surface glycolipid that is present in all gram-negative enteric bacteria. The carbohydrate portion of the polymer contains: N-acetyl-D-glucosamine (GlcNAc), N-acetyl-D-mannosaminouronic acid (ManNAcA) and 4-acetamido-4,6-dideoxy-D-galactose (Fuc4NAc). These amino sugars are linked to form linear polysaccharide chains. In addition, the hydroxyl groups at position 6 of the GlcNAc residues are nonstochiometrically substituted with O-acetyl groups.
http://purl.obolibrary.org/obo/UPa_UPA00567	bioluminescence	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Bioluminescence is the production and emission of light by a living organism as the result of a chemical reaction during which chemical energy is converted to light energy.
http://purl.obolibrary.org/obo/UPa_UPA00568	bacterial bioluminescence	http://purl.obolibrary.org/obo/UPa_UPA00567	bioluminescence		Bacterial bioluminescence is a tightly regulated energy-consuming process. In Vibrio fischeri, luminescence is produced when luciferase, composed of LuxA and LuxB, converts FMNH2, O2 and an aliphatic aldehyde (RCHO) to FMN, water and an aliphatic acid. LuxC and LuxE recycle the aliphatic acid, which is also produced by LuxD, to regenerate the RCHO substrate, while LuxG and other proteins in the cell reduce FMN using NADH to supply luciferase with FMNH2 [PMID:17590235].
http://purl.obolibrary.org/obo/UPa_UPA00569	fatty acid reduction for biolumincescence	http://purl.obolibrary.org/obo/UPa_UPA00568	bacterial bioluminescence		Fatty acid reduction for bacterial biolumincescence.
http://purl.obolibrary.org/obo/UPa_UPA00570	pyrimidine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00523	heterocycle metabolism		Metabolism of pyrimidine derivative compounds (nucleotides, nucleosides, nucleobases).
http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00570	pyrimidine metabolism		Biosynthesis of pyrimidine derivative compounds (nucleotides, nucleosides, nucleobases). Cytosine, thymine, and uracil are the three nucleobases found in nucleic acids.
http://purl.obolibrary.org/obo/UPa_UPA00572	UMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis		Biosynthesis of UMP nucleotide (uridine monophosphate). UMP is the pivotal nucleotide from which uridine nucleotide di- and triphosphates are formed by ATP-dependent kinases.
http://purl.obolibrary.org/obo/UPa_UPA00573	pyrimidine salvage	http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis		In pyrimidine salvage, nucleosides generated by DNA and RNA breakdown are converted back to nucleotide monophosphates, enabling them to re-enter the pathways of pyrimidine biosynthesis. Pyrimidine salvage, similarly to purines, involves a single enzymatic step but, unlike purines, occurs at the nucleoside rather than the base level in humans, with salvage predominating over synthesis.
http://purl.obolibrary.org/obo/UPa_UPA00575	dTTP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis		Biosynthesis of dTTP (deoxythymidine triphosphate).
http://purl.obolibrary.org/obo/UPa_UPA00576	CTP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis		Biosynthesis of CTP nucleotide (cytidine triphosphate).
http://purl.obolibrary.org/obo/UPa_UPA00577	dTMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis		Biosynthesis of dTMP (deoxythymidine monophosphate).
http://purl.obolibrary.org/obo/UPa_UPA00580	pyrimidine degradation	http://purl.obolibrary.org/obo/UPa_UPA00570	pyrimidine metabolism		Degradation of pyrimidine derivative compounds (nucleotides, nucleosides, nucleobases).
http://purl.obolibrary.org/obo/UPa_UPA00581	uracil degradation	http://purl.obolibrary.org/obo/UPa_UPA00580	pyrimidine degradation		Degradation of uracil nucleobase.
http://purl.obolibrary.org/obo/UPa_UPA00583	purine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00523	heterocycle metabolism		Metabolism of purine derivative compounds (nucleotides, nucleosides, nucleobases).
http://purl.obolibrary.org/obo/UPa_UPA00584	purine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00583	purine metabolism		Biosynthesis of purine derivative compounds (nucleotides, nucleosides, nucleobases).
http://purl.obolibrary.org/obo/UPa_UPA00585	purine degradation	http://purl.obolibrary.org/obo/UPa_UPA00583	purine metabolism		Degradation of purine derivative compounds (nucleotides, nucleosides, nucleobases). Purine degradation has an essential role in nitrogen metabolism in most organism.
http://purl.obolibrary.org/obo/UPa_UPA00586	purine biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00584	purine biosynthesis		In purine salvage, nucleosides generated by DNA and RNA breakdown are converted back to nucleotide monophosphates, enabling them to re-enter the pathways of purine biosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00587	adenine biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00586	purine biosynthesis via salvage pathway		Biosynthesis of adenine through purine salvage.
http://purl.obolibrary.org/obo/UPa_UPA00589	inosine biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00594	inosine biosynthesis		Biosynthesis of inosine through purine salvage.
http://purl.obolibrary.org/obo/UPa_UPA00590	hypoxanthine biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00586	purine biosynthesis via salvage pathway		Biosynthesis of hypoxanthine through purine salvage.
http://purl.obolibrary.org/obo/UPa_UPA00592	AMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00488	purine nucleotide biosynthesis		Biosynthesis of adenosine 5'-phosphate, a purine nucleotide.
http://purl.obolibrary.org/obo/UPa_UPA00593	purine biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00584	purine biosynthesis		Biosynthesis of purine derivative via de novo pathway.
http://purl.obolibrary.org/obo/UPa_UPA00594	inosine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00524	purine base biosynthesis		Biosynthesis of inosine purine nucleobase.
http://purl.obolibrary.org/obo/UPa_UPA00595	purine base degradation	http://purl.obolibrary.org/obo/UPa_UPA00585	purine degradation		Degradation of purine base compounds.
http://purl.obolibrary.org/obo/UPa_UPA00596	second messenger metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of second messengers, molecular signals (ions or small molecules) released into the cytosol, thereby helping relay the signal within the cell.
http://purl.obolibrary.org/obo/UPa_UPA00597	second messenger biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00596	second messenger metabolism		Biosynthesis of second messengers, molecular signals (ions or small molecules) released into the cytosol, thereby helping relay the signal within the cell.
http://purl.obolibrary.org/obo/UPa_UPA00598	cyclic nucleotide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00759	cyclic nucleotide metabolism		Biosynthesis of cyclic nucleotides, any nucleotide in which the phosphate group is bonded to two of the sugar's hydroxyl groups, forming a cyclical or ring structure. Examples: cAMP, cGMP, c-di-GMP, etc.
http://purl.obolibrary.org/obo/UPa_UPA00599	3',5'-cyclic di-GMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00598	cyclic nucleotide biosynthesis		Biosynthesis of cyclic dinucleotide 3',5'-cyclic di-GMP (c-di-GMP), a purine nucleotide emerging as a novel global second messenger in bacteria. In many bacteria bis-(3',5')-cyclic dimeric guanosine monophosphate (c-di-GMP) signaling determines the timing and amplitude of complex biological processes from biofilm formation and virulence to photosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00600	XMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00488	purine nucleotide biosynthesis		Biosynthesis of xanthosine 5'-phosphate (XMP purine nucleotide).
http://purl.obolibrary.org/obo/UPa_UPA00605	purine nucleoside metabolism	http://purl.obolibrary.org/obo/UPa_UPA00583	purine metabolism		Metabolism of purine nucleoside compounds.
http://purl.obolibrary.org/obo/UPa_UPA00606	purine nucleoside salvage	http://purl.obolibrary.org/obo/UPa_UPA00608	purine nucleoside biosynthesis		Salvage of purine nucleoside compounds.
http://purl.obolibrary.org/obo/UPa_UPA00607	purine nucleoside degradation	http://purl.obolibrary.org/obo/UPa_UPA00605	purine nucleoside metabolism		Degradation of purine nucleoside compounds.
http://purl.obolibrary.org/obo/UPa_UPA00608	purine nucleoside biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00605	purine nucleoside metabolism		Biosynthesis of purine nucleoside compounds.
http://purl.obolibrary.org/obo/UPa_UPA00611	alcohol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of alcohol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00612	alcohol degradation	http://purl.obolibrary.org/obo/UPa_UPA00611	alcohol metabolism		Degradation of alcohol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00613	polyol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00611	alcohol metabolism		Metabolism of polyol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00614	polyol degradation	http://purl.obolibrary.org/obo/UPa_UPA00613	polyol metabolism		Degradation of polyol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00615	glycerol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00613	polyol metabolism		Metabolism of the trihydric alcohol, glycerol.
http://purl.obolibrary.org/obo/UPa_UPA00616	glycerol degradation	http://purl.obolibrary.org/obo/UPa_UPA00615	glycerol metabolism		Degradation of glycerol, a trihydric alcohol. Two possible routes of glycerol catabolism have been proposed. In the first pathway, glycerol is phosphorylated to glycerol-3-phosphate by glycerol kinase, and then converted to dihydroxyacetone phosphate by glycerol-3-phosphate dehydrogenase. In the second pathway, glycerol is converted to dihydroxyacetone by NAD-dependent glycerol dehydrogenase, and then phosphorylated to dihydroxyacetone phosphate by dihydroxyacetone kinase.
http://purl.obolibrary.org/obo/UPa_UPA00620	propanediol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00615	glycerol metabolism		Metabolism of diol alcohol propanediol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00621	1,2-propanediol degradation	http://purl.obolibrary.org/obo/UPa_UPA00620	propanediol metabolism		Degradation of the diol alcohol, 1,2-propanediol (propane-1,2-diol).
http://purl.obolibrary.org/obo/UPa_UPA00622	alcohol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00613	polyol metabolism		Biosynthesis of alcohol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00623	polyol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00622	alcohol biosynthesis		Biosynthesis of polyol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00624	glycerol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00623	polyol biosynthesis		Biosynthesis of the trihydric alcohol, glycerol (1,2,3-propanetriol).
http://purl.obolibrary.org/obo/UPa_UPA00625	(R,R)-butane-2,3-diol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00613	polyol metabolism		Metabolism of 2,3-butanediol. 2,3-butanediol (2,3-BDL), which is very important for a variety of chemical feedstocks and liquid fuels, can be derived from the bioconversion of natural resources. The metabolic function of 2,3-butanediol is not yet known, although it may play a role in preventing intracellular acidification by changing the metabolism from acid production to the formation of a neutral compound.
http://purl.obolibrary.org/obo/UPa_UPA00627	amino-sugar degradation	http://purl.obolibrary.org/obo/UPa_UPA00456	amine and polyamine degradation		Degradation of amino-sugar compounds.
http://purl.obolibrary.org/obo/UPa_UPA00628	N-acetylneuraminate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00216	amino-sugar metabolism		Metabolism of N-acetylneuramate, an amino sugar component of the cell surface structures.
http://purl.obolibrary.org/obo/UPa_UPA00630	N-acetylneuraminate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00649	amino-sugar biosynthesis		Biosynthesis of N-acetylneuraminic acid (Neu5Ac), the precursor of sialic acids, a group of important molecules in biological recognition systems.
http://purl.obolibrary.org/obo/UPa_UPA00631	exopolysaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of exopolysaccharide compounds. Pseudomonas solanacearum.
http://purl.obolibrary.org/obo/UPa_UPA00632	teichoic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00700	organic acid biosynthesis		Biosynthesis of teichoic acids (TAs), a group of phosphate-rich anionic extracellular polysaccharides found covalently bound to peptidoglycan in gram-positive bacteria TAs are polymers of glycerol or ribitol linked via phosphodiester bonds. These acids can be found in the cell wall of gram-positive bacteria, such as Staphylococci, Streptococci, Bacillus, Clostridium, Corynebacterium and Listeria, and appear to extend to the surface of the peptidoglycan layer. Teichoic acids are not found in the gram-negative bacteria. Teichoic acids are negatively charged and therefore contribute to the negative charge of the gram-positive cell wall. They may also provide structural support for the cell wall and act as antigen.
http://purl.obolibrary.org/obo/UPa_UPA00633	L-glutamate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00700	organic acid biosynthesis		Biosynthesis of L-glutamate amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00635	L-glutamate biosynthesis via GDH pathway	http://purl.obolibrary.org/obo/UPa_UPA00633	L-glutamate biosynthesis		Biosynthesis of L-glutamate amino-acid via glutamate dehydrogenase (GDH).
http://purl.obolibrary.org/obo/UPa_UPA00636	beta-glucan biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of beta-glucans.
http://purl.obolibrary.org/obo/UPa_UPA00637	osmoregulated periplasmic glucan (OPG) biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00636	beta-glucan biosynthesis		Biosynthesis of osmoregulated periplasmic glucans (OPGs). OPGs occur in a wide variety of Gram-negative bacterial species. The only sugars found in the backbone of OPGs are glucosyl residues, which are bound with beta-glucosidic linkages. Generally, OPG synthesis is activated by conditions of low osmolarity. OPGs vary from 5 to 25 glucosyl residues per molecule and the glucose backbones show structural diversity among different species. [PMID:17906125].
http://purl.obolibrary.org/obo/UPa_UPA00638	nitric oxide reduction	http://purl.obolibrary.org/obo/UPa_UPA00652	nitrate reduction (denitrification)		Reduction of nitric oxide (NO), a compound present throughout the biosphere. In humans, tightly regulated NO synthases produce sufficient NO to poison pathogens, opportunistic organisms, and neoplastic tissue. Nitric-oxide reductases metabolize NO to N2O in anaerobic denitrifying bacteria and fungi and likely serve an additional role in minimizing NO toxicity.
http://purl.obolibrary.org/obo/UPa_UPA00639	methanogenesis	http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism		Biosynthesis of methane, the simplest alkane.
http://purl.obolibrary.org/obo/UPa_UPA00641	methanogenesis from methanol	http://purl.obolibrary.org/obo/UPa_UPA00639	methanogenesis		Biosynthesis of methane from methanol.
http://purl.obolibrary.org/obo/UPa_UPA00642	methanogenesis from acetate	http://purl.obolibrary.org/obo/UPa_UPA00639	methanogenesis		Biosynthesis of methane from acetate. Acetate serves as a growth substrate for acetotrophic methanogens including the anaerobic archaeon Methanosarcina thermophila. Activation of acetate into acetyl-CoA is described in 'Acetyl-CoA biosynthesis' pathway.
http://purl.obolibrary.org/obo/UPa_UPA00643	methanogenesis from methylamine	http://purl.obolibrary.org/obo/UPa_UPA00650	methanogenesis from methylated amine		Biosynthesis of methane from monomethylamine.
http://purl.obolibrary.org/obo/UPa_UPA00644	methanogenesis from dimethylamine	http://purl.obolibrary.org/obo/UPa_UPA00650	methanogenesis from methylated amine		Biosynthesis of methane from dimethylamine.
http://purl.obolibrary.org/obo/UPa_UPA00645	methanogenesis from trimethylamine	http://purl.obolibrary.org/obo/UPa_UPA00650	methanogenesis from methylated amine		Biosynthesis of methane from trimethylamine.
http://purl.obolibrary.org/obo/UPa_UPA00648	IMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00488	purine nucleotide biosynthesis		Biosynthesis of inosine 5'-phosphate, a purine nucleotide.
http://purl.obolibrary.org/obo/UPa_UPA00649	amino-sugar biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Biosynthesis of amino-sugar compounds.
http://purl.obolibrary.org/obo/UPa_UPA00650	methanogenesis from methylated amine	http://purl.obolibrary.org/obo/UPa_UPA00639	methanogenesis		Biosynthesis of methane from methylated amines (mono-, di- or trimethylamine).
http://purl.obolibrary.org/obo/UPa_UPA00651	3-deoxy-D-manno-octulosonate 4-phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Biosynthesis of 3-deoxy-D-manno-octulosonate 4-phosphate (KDO 4-phosphate).
http://purl.obolibrary.org/obo/UPa_UPA00653	nitrate reduction (assimilation)	http://purl.obolibrary.org/obo/UPa_UPA00654	nitrate reduction		Reduction of nitrate into to nitrite via assimilation pathway.
http://purl.obolibrary.org/obo/UPa_UPA00654	nitrate reduction	http://purl.obolibrary.org/obo/UPa_UPA00045	nitrogen metabolism		The uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances. [GO:0042128].
http://purl.obolibrary.org/obo/UPa_UPA00656	short-chain fatty acid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00199	fatty acid metabolism		Metabolism of short-chain fatty acid compounds.
http://purl.obolibrary.org/obo/UPa_UPA00657	rhamnolipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis		Biosynthesis of rhamnolipid compounds. Rhamnolipids are extracellular biosurfactants and virulence factors secreted by the opportunistic human pathogen Pseudomonas aeruginosa that are required for swarming motility.
http://purl.obolibrary.org/obo/UPa_UPA00658	polyunsaturated fatty acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis		Biosynthesis of polyunsaturated fatty acid compounds.
http://purl.obolibrary.org/obo/UPa_UPA00659	fatty acid beta-oxidation	http://purl.obolibrary.org/obo/UPa_UPA00430	fatty acid degradation		The metabolic oxidation of a long-chain fatty acid by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A [GO:0006635].
http://purl.obolibrary.org/obo/UPa_UPA00660	mitochondrial fatty acid beta-oxidation	http://purl.obolibrary.org/obo/UPa_UPA00659	fatty acid beta-oxidation		Beta-oxidation of fatty acids in mitochondrion.
http://purl.obolibrary.org/obo/UPa_UPA00661	peroxisomal fatty acid beta-oxidation	http://purl.obolibrary.org/obo/UPa_UPA00199	fatty acid metabolism		Beta-oxidation of fatty acids in peroxisome.
http://purl.obolibrary.org/obo/UPa_UPA00662	prostaglandin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis		Biosynthesis of prostaglandins, a group of lipid compounds that are derived enzymatically from fatty acids and have important functions in the animal body. Every prostaglandin contains 20 carbon atoms, including a 5-carbon ring.
http://purl.obolibrary.org/obo/UPa_UPA00663	lipoprotein biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the nonprotein moiety consists of a lipid or lipids [GO:0042158] Both gram-positive and gram-negative bacteria contain lipoproteins that are a functionally diverse group of surface proteins. The roles assigned to lipoproteins include substrate binding coupled to ABC transport systems, sensing of environmental signals, antibiotic resistance, respiration, germination, conjugation, adherence to and invasion of eukaryotic cells, control of protein secretion and folding, modulation of the immune response, and maintenance of envelope integrity. Upon processing, lipoproteins are ultimately tethered to the membrane via a lipid moiety, diacylglycerol, which is covalently bound to an N-terminal conserved cysteine residue.
http://purl.obolibrary.org/obo/UPa_UPA00664	lipoprotein biosynthesis (diacylglyceryl transfer)	http://purl.obolibrary.org/obo/UPa_UPA00663	lipoprotein biosynthesis		The first step of lipoprotein biosynthesis consist of lipidation reaction, carried out by the enzyme lipoprotein diacylglyceryl transferase (Lgt).
http://purl.obolibrary.org/obo/UPa_UPA00665	lipoprotein biosynthesis (signal peptide cleavage)	http://purl.obolibrary.org/obo/UPa_UPA00663	lipoprotein biosynthesis		The second step of lipoprotein biosynthesis consist of cleavage of the signal peptide. The enzyme responsible for this reaction is the lipoprotein-specific signal peptidase II (Lsp), which recognizes a genuine L(-3)-S/A(-2)-A/G(-1)-C(+1) lipobox.
http://purl.obolibrary.org/obo/UPa_UPA00666	lipoprotein biosynthesis (N-acyl transfer)	http://purl.obolibrary.org/obo/UPa_UPA00663	lipoprotein biosynthesis		The first step of lipoprotein biosynthesis consist of addition of an N-acyl moiety to the amino group of the N-terminal cysteine, This reaction is carried out by the enzyme N-acyl-transferase (Lnt).
http://purl.obolibrary.org/obo/UPa_UPA00667	L-arabinan degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of L-arabinan, a branched homopolymer of L-arabinose.
http://purl.obolibrary.org/obo/UPa_UPA00668	chlorophyll biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of chlorophyll, a green pigment found in most plants, algae, and cyanobacteria.
http://purl.obolibrary.org/obo/UPa_UPA00669	bacteriochlorophyll biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00670	chlorophyll biosynthesis (light-independent)	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Light-independent biosynthesis of chlorophyll.
http://purl.obolibrary.org/obo/UPa_UPA00671	bacteriochlorophyll biosynthesis (light-independent)	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Light-independent biosynthesis of bacteriochlorophyll.
http://purl.obolibrary.org/obo/UPa_UPA00672	pigment metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of pigment or biochrome, any material resulting in color of plant or animal cells, which is the result of selective color absorption.
http://purl.obolibrary.org/obo/UPa_UPA00673	pigment degradation	http://purl.obolibrary.org/obo/UPa_UPA00672	pigment metabolism		Degradation of pigment or biochrome.
http://purl.obolibrary.org/obo/UPa_UPA00674	chlorophyll degradation	http://purl.obolibrary.org/obo/UPa_UPA00679	porphyrin-containing compound degradation		Degradation of chlorophyll, the green pigment found in photosynthetic organisms.
http://purl.obolibrary.org/obo/UPa_UPA00675	heterocycle biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00523	heterocycle metabolism		Biosynthesis of heterocyclic compounds.
http://purl.obolibrary.org/obo/UPa_UPA00676	heterocycle degradation	http://purl.obolibrary.org/obo/UPa_UPA00523	heterocycle metabolism		Degradation of heterocyclic compounds.
http://purl.obolibrary.org/obo/UPa_UPA00677	porphyrin-containing compound metabolism	http://purl.obolibrary.org/obo/UPa_UPA00523	heterocycle metabolism		Metabolism of porphyrin-containing compounds. A porphyrin is a heterocyclic macrocycle made from 4 pyrrole subunits linked on opposite sides (alpha position) through 4 methine bridges (=CH-). Porphyrins combine readily with metals, coordinating with them in the central cavity. Iron- (heme), magnesium- (chlorophyll), zinc-, copper-, nickel-, and cobalt- containing porphyrins are known, and many other metals can be inserted.
http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00682	macrocycle biosynthesis		The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. A porphyrin is a heterocyclic macrocycle made from 4 pyrrole subunits linked on opposite sides (alpha position) through 4 methine bridges (=CH-). Porphyrins combine readily with metals, coordinating with them in the central cavity. Iron- (heme), magnesium- (chlorophyll), zinc-, copper-, nickel-, and cobalt- containing porphyrins are known, and many other metals can be inserted.
http://purl.obolibrary.org/obo/UPa_UPA00679	porphyrin-containing compound degradation	http://purl.obolibrary.org/obo/UPa_UPA00681	macrocycle degradation		Degradation of any member of a large group of derivatives or analogs of porphyrin. A porphyrin is a heterocyclic macrocycle made from 4 pyrrole subunits linked on opposite sides (alpha position) through 4 methine bridges (=CH-). Porphyrins combine readily with metals, coordinating with them in the central cavity. Iron- (heme), magnesium- (chlorophyll), zinc-, copper-, nickel-, and cobalt- containing porphyrins are known, and many other metals can be inserted.
http://purl.obolibrary.org/obo/UPa_UPA00680	macrocycle metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolism of macrocycle. A macrocycle is, as defined by IUPAC, 'a cyclic macromolecule or a macromolecular cyclic portion of a molecule'.
http://purl.obolibrary.org/obo/UPa_UPA00681	macrocycle degradation	http://purl.obolibrary.org/obo/UPa_UPA00680	macrocycle metabolism		Degradation of macrocycle, like heme, chlorophyll, vitamin B12, etc.
http://purl.obolibrary.org/obo/UPa_UPA00682	macrocycle biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00680	macrocycle metabolism		Biosynthesis of macrocycle, like heme, chlorophyll, vitamin B12, etc.
http://purl.obolibrary.org/obo/UPa_UPA00683	spheroidene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00386	carotenoid biosynthesis		Biosynthesis of spheroidene carotenoids from neurosporene.
http://purl.obolibrary.org/obo/UPa_UPA00684	protoheme degradation	http://purl.obolibrary.org/obo/UPa_UPA00679	porphyrin-containing compound degradation		Degradation of heme. Bilirubin is a yellow breakdown product of normal heme catabolism.
http://purl.obolibrary.org/obo/UPa_UPA00685	(2,4-dichlorophenoxy)acetate degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of (2,4-dichlorophenoxy)acetate, a chlorinated phenoxy compound. (2,4-dichlorophenoxy)acetate functions as a systemic herbicide and is used to control many types of broadleaf weeds.
http://purl.obolibrary.org/obo/UPa_UPA00686	(2,4,5-trichlorophenoxy)acetate degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of (2,4,5-trichlorophenoxy)acetate, a chlorinated phenoxy compound.
http://purl.obolibrary.org/obo/UPa_UPA00688	dichloromethane degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of dichloromethane, a highly volatile solvent which finds application in a wide variety of industrial and commercial processes. Dibromomethane has been observed to occur naturally [PMID:7272274].
http://purl.obolibrary.org/obo/UPa_UPA00689	gamma-hexachlorocyclohexane degradation	http://purl.obolibrary.org/obo/UPa_UPA00690	hexachlorocyclohexane degradation		Degradation of gamma-hexachlorocyclohexane (g-HCH, BHC, lindane), a halogenated organic insecticide that has been used worldwide for agriculture and public health. It is degraded rapidly under anaerobic conditions, but is considered extremely persistent in upland soil.
http://purl.obolibrary.org/obo/UPa_UPA00690	hexachlorocyclohexane degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of hexachlorocyclohexane (HCH), a xenobiotic compound used extensively against agricultural pests and in public health programs for the control of mosquitoes. Commercial formulations of HCH consist of a mixture of four isomers, alpha, beta, gamma, and delta. While all these isomers pose serious environmental problems, beta-HCH is more problematic due to its longer persistence in the environment.
http://purl.obolibrary.org/obo/UPa_UPA00691	pentachlorophenol degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of pentachlorophenol (PCP), a chlorinated insecticide and fungicide. It is used primarily to protect timber from fungal rot and wood boring insects. PCP is significantly toxic to mammals, plants, and many microorganisms. Despite this, bacteria have been identified that are resistant to relatively high PCP concentrations and can metabolize it to carbon dioxide and chloride. Bacteria have been used successfully in PCP bioremediation.
http://purl.obolibrary.org/obo/UPa_UPA00692	cellulose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Metabolism of cellulose, the most abundant biopolymer on earth, recognized as the major component of plant biomass but also representative of microbial extracellular polymers. Bacterial cellulose (BC) belongs to specific product of primary metabolism and is mainly a protective coating, whereas plant cellulose (PC) plays a structural role. Cellulose is an unbranched polymer of beta-1-4 linked glucopyranose residues Plant cellulose and bacterial cellulose have the same chemical structure, but different physical and chemical properties.
http://purl.obolibrary.org/obo/UPa_UPA00693	cellulose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00692	cellulose metabolism		Biosynthesis of cellulose.
http://purl.obolibrary.org/obo/UPa_UPA00694	bacterial cellulose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00693	cellulose biosynthesis		Biosynthesis of bacterial cellulose.
http://purl.obolibrary.org/obo/UPa_UPA00695	plant cellulose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00693	cellulose biosynthesis		Biosynthesis of plant cellulose.
http://purl.obolibrary.org/obo/UPa_UPA00696	cellulose degradation	http://purl.obolibrary.org/obo/UPa_UPA00692	cellulose metabolism		Degradation of cellulose.
http://purl.obolibrary.org/obo/UPa_UPA00697	hemicellulose degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of hemicellulose, a branched polymer of sugar monomers. For instance, besides glucose, sugar monomers in hemicellulose can include xylose, mannose, galactose, rhamnose, and arabinose. Hemicelluloses contain most of the D-pentose sugars, and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present.
http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. [GO:0006082].
http://purl.obolibrary.org/obo/UPa_UPA00699	organic acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism		Degradation of organic acids.
http://purl.obolibrary.org/obo/UPa_UPA00700	organic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism		Biosynthesis of organic acids.
http://purl.obolibrary.org/obo/UPa_UPA00701	lactate oxidation	http://purl.obolibrary.org/obo/UPa_UPA00699	organic acid degradation		Oxidation of lactic acid.
http://purl.obolibrary.org/obo/UPa_UPA00705	oxidative phosphorylation	http://purl.obolibrary.org/obo/UPa_UPA00426	energy metabolism		Oxidative phosphorylation is a metabolic pathway that uses energy released by the oxidation of nutrients to produce adenosine triphosphate (ATP).
http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Pathways involved in the degradation of aromatic compounds.
http://purl.obolibrary.org/obo/UPa_UPA00707	cresol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00611	alcohol metabolism		Metabolism of cresols (methylphenols) organic compounds. They are a widely occurring natural and manufactured group of aromatic organic compounds which are categorized as phenols.
http://purl.obolibrary.org/obo/UPa_UPA00708	p-cresol degradation	http://purl.obolibrary.org/obo/UPa_UPA00707	cresol metabolism		Degradation of para-cresol, a toxic phenol.
http://purl.obolibrary.org/obo/UPa_UPA00709	flavonoid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00710	phenylpropanoid metabolism		The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00710	phenylpropanoid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Metabolism of phenylpropanoids, a group of compounds that are widely available in natural environments. Phenylpropanoids can originate from putrefaction of proteins in soil or as breakdown products of several constituents of plants, such as lignin, various oils, and resins.
http://purl.obolibrary.org/obo/UPa_UPA00711	phenylpropanoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of phenylpropanoid compounds, the aromatic derivatives of trans-cinnamic acid.
http://purl.obolibrary.org/obo/UPa_UPA00712	phenylpropanoid degradation	http://purl.obolibrary.org/obo/UPa_UPA00710	phenylpropanoid metabolism		Microbial catabolism of phenylpropanoid compounds plays an important role not only in the natural degradative cycle of these aromatic molecules but also in their industrial applications such as wine making, aging, and storage.
http://purl.obolibrary.org/obo/UPa_UPA00715	terpenoid degradation	http://purl.obolibrary.org/obo/UPa_UPA00423	terpene metabolism		Degradation of terpene compounds.
http://purl.obolibrary.org/obo/UPa_UPA00716	monoterpene metabolism	http://purl.obolibrary.org/obo/UPa_UPA00423	terpene metabolism		Metabolism of monoterpene compoundss, terpenes with a C10 structure. [CHEBI:35187].
http://purl.obolibrary.org/obo/UPa_UPA00717	monoterpene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00716	monoterpene metabolism		Biosynthesis of monoterpene compounds, terpenes with a C10 structure.
http://purl.obolibrary.org/obo/UPa_UPA00718	D-camphor metabolism	http://purl.obolibrary.org/obo/UPa_UPA00716	monoterpene metabolism		Metabolism of D-camphor, a white, crystalline solid monoterpene ketone.
http://purl.obolibrary.org/obo/UPa_UPA00719	(R)-camphor degradation	http://purl.obolibrary.org/obo/UPa_UPA00718	D-camphor metabolism		Degradation of (R)-camphor, a white, crystalline solid monoterpene ketone.
http://purl.obolibrary.org/obo/UPa_UPA00720	(R)-camphor biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00718	D-camphor metabolism		Biosynthesis of (R)-camphor, a white, crystalline solid monoterpene ketone.
http://purl.obolibrary.org/obo/UPa_UPA00721	linalool degradation	http://purl.obolibrary.org/obo/UPa_UPA00137	monoterpene degradation		Degradation of linalool, a naturally-occurring terpene alcohol compound found in many flowers and spice plants.
http://purl.obolibrary.org/obo/UPa_UPA00722	steroid degradation	http://purl.obolibrary.org/obo/UPa_UPA00715	terpenoid degradation		Degradation of steroid compounds. A steroid is a terpenoid lipid characterized by a carbon skeleton with four fused rings, generally arranged in a 6-6-6-5 fashion. Steroids vary by the functional groups attached to these rings and the oxidation state of the rings. Hundreds of distinct steroids are found in plants, animals, and fungi. All steroids are made in cells either from the sterol lanosterol (animals and fungi) or the sterol cycloartenol (plants). Both sterols are derived from the cyclization of the triterpene squalene.
http://purl.obolibrary.org/obo/UPa_UPA00723	flavonoid degradation	http://purl.obolibrary.org/obo/UPa_UPA00712	phenylpropanoid degradation		The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00724	quercetin degradation	http://purl.obolibrary.org/obo/UPa_UPA00723	flavonoid degradation		Degradation of quercetin, the aglycone form of a number of other flavonoid glycosides.
http://purl.obolibrary.org/obo/UPa_UPA00725	scopolamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00330	tropane alkaloid biosynthesis		Biosynthesis of scopolamine (hyoscine), a tropane alkaloid compound with muscarinic antagonist effects. Scopolamine is obtained from plants of the family Solanaceae (nightshades), such as henbane or jimson weed (Datura species). It is among the secondary metabolites of these plants.
http://purl.obolibrary.org/obo/UPa_UPA00727	coronatine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00477	phytotoxin biosynthesis		Biosynthesis of coronatine, a phytotoxin produced by some plant-pathogenic bacteria. It has been shown that coronatine mimics the action of methyl jasmonate (MeJA) in plants. MeJA is a plant-signaling molecule involved in stress responses such as wounding and pathogen attack.
http://purl.obolibrary.org/obo/UPa_UPA00728	phenol degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of phenol.
http://purl.obolibrary.org/obo/UPa_UPA00729	2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification		Biosynthesis of 2-methylthio-N-6-isopentenyl adenosine (ms2i6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs that read codons beginning with U except tRNA(i.v. Ser) in Escherichia coli. In Salmonella typhimurium, 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A; also referred to as 2-methylthio cis-ribozeatin) is found in tRNA, most likely in the species that have ms2i6A in E. coli.
http://purl.obolibrary.org/obo/UPa_UPA00730	carboxydiphenyl ether degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of 3- and 4-carboxydiphenyl ether compounds.
http://purl.obolibrary.org/obo/UPa_UPA00731	sabinene hydrate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00717	monoterpene biosynthesis		Biosynthesis of sabinene hydrate, a bicyclic monoterpene.
http://purl.obolibrary.org/obo/UPa_UPA00732	4-aminobutanoate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		Metabolism of 4-aminobutanoate (GABA; gamma-aminobutyrate; 4-aminobutyrate).
http://purl.obolibrary.org/obo/UPa_UPA00733	4-aminobutanoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00854	nonprotein amino-acid degradation		Degradation of 4-aminobutanoate (GABA; gamma-aminobutyrate; 4-aminobutyrate).
http://purl.obolibrary.org/obo/UPa_UPA00734	acetylacetone degradation	http://purl.obolibrary.org/obo/UPa_UPA00410	ketone degradation		Degradation of the diketone acetylacetone (pentane-2,4-dione; 2,4-dioxopentane). Acetylacetone is a widely used industrial chemical with toxic side effects including central neurotoxicity and possible effects on the immune system of mammals, as well as toxicity towards various aquatic organisms and micro-organisms.
http://purl.obolibrary.org/obo/UPa_UPA00735	opine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00465	secondary metabolite metabolism		Crown gall tumors and hairy roots are plant neoplasias induced by pathogenic members of the genus Agrobacterium. The transformed plant cells are characterized by low MW compounds called opines. The biosynthesis of these compounds is mediated by specific enzymes encoded by genes contained in a small segment of DNA (known as the T-DNA, for 'transfer DNA') inserted by the pathogen bacterium in the plant genome during infection. The opines produced by plant tumors serve as nutrient sources for the pathogenic agrobacteria. Each strain of Agrobacterium induces and catabolizes a specific set of opines.
http://purl.obolibrary.org/obo/UPa_UPA00736	mannopine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00735	opine metabolism		Biosynthesis of mannopine (N-1-(D-mannityl)-L-glutamine), the head member of the mannityl family of opines. Mannopine is found in crown gall tumors.
http://purl.obolibrary.org/obo/UPa_UPA00737	octopine degradation	http://purl.obolibrary.org/obo/UPa_UPA00735	opine metabolism		Degradation of octopine (N2-(D-l-carboxyethyl)-L-arginine), the first opine discovered in 1927 in octopus muscle and later in crown gall tumors. It is also found in other cephalopod species and lamellibranchs. Octopine is the head member of the octopine family of opines.
http://purl.obolibrary.org/obo/UPa_UPA00738	1,5-anhydro-D-fructose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of 1,5-anhydro-D-fructose.
http://purl.obolibrary.org/obo/UPa_UPA00739	benzoyl-CoA degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of benzoyl-CoA. Many aromatic compounds are anaerobically oxidized to CO2 via benzoyl-CoA as the common aromatic intermediate.
http://purl.obolibrary.org/obo/UPa_UPA00740	3-chloro-1,2-epoxypropane degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of 3-chloro-1,2-epoxypropane.
http://purl.obolibrary.org/obo/UPa_UPA00741	glucosinolate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of glucosinolates, a class of organic compounds that contain sulfur, nitrogen and a group derived from glucose. Glucosinolates occur as secondary metabolites of many plants of the order Brassicales (especially in the family Brassicaceae, furthermore Capparidaceae and Caricaceae), but also in the genus Dryetes (family Euphorbiaceae). Plants use substances derived from glucosinolates as natural pesticides and as defense against herbivores.
http://purl.obolibrary.org/obo/UPa_UPA00742	phenylglucosinolate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00741	glucosinolate biosynthesis		Biosynthesis of phenylglucosinolate.
http://purl.obolibrary.org/obo/UPa_UPA00743	butanol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00622	alcohol biosynthesis		Biosynthesis of butanol, a primary alcohol with a molecular formula of C4H10O. There are four isomeric structures for butanol. Clostridium acetobutylicum is one of the few organisms known to produce 1-butanol as a major fermentation product.
http://purl.obolibrary.org/obo/UPa_UPA00745	galactose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Biosynthesis of galactose, the aldohexose galacto-hexose.
http://purl.obolibrary.org/obo/UPa_UPA00746	catecholamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of catecholamines, a group of chemical compounds derived from the amino-acid tyrosine containing catechol and amine groups. The most abundant catecholamines are adrenaline (epinephrine), noradrenaline (norepinephrine) and dopamine.
http://purl.obolibrary.org/obo/UPa_UPA00750	catechol degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of catechol (1,2-dihydroxybenzene).
http://purl.obolibrary.org/obo/UPa_UPA00751	phospholipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00085	phospholipid metabolism		Biosynthesis of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
http://purl.obolibrary.org/obo/UPa_UPA00752	phospholipid degradation	http://purl.obolibrary.org/obo/UPa_UPA00085	phospholipid metabolism		Degradation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Biosynthesis of aromatic compounds.
http://purl.obolibrary.org/obo/UPa_UPA00755	chondroitin sulfate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of chondroitin sulfate, a sulfated glycosaminoglycan (GAG) composed of a chain of alternating sugars (N-acetylgalactosamine and glucuronic acid). It is usually found attached to proteins as part of a proteoglycan.
http://purl.obolibrary.org/obo/UPa_UPA00756	heparan sulfate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00861	glycosaminoglycan biosynthesis		Biosynthesis of heparan sulfate (HS), a linear polysaccharide found in all animal tissues. Heparan sulfate is a member of the glycosaminoglycan family of carbohydrates and is very closely related in structure to heparin. The most common disaccharide unit within heparan sulfate is composed of a glucuronic (GlcA) linked to N-acetylglucosamine (GlcNAc) typically making up around 50% of the total disaccharide units. It is usually found attached to proteins as part of a proteoglycan.
http://purl.obolibrary.org/obo/UPa_UPA00758	nucleotide degradation	http://purl.obolibrary.org/obo/UPa_UPA00486	nucleotide metabolism		Degradation of nucleotides.
http://purl.obolibrary.org/obo/UPa_UPA00759	cyclic nucleotide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00486	nucleotide metabolism		Biosynthesis of cyclic nucleotides, any nucleotide in which the phosphate group is bonded to two of the sugar's hydroxyl groups, forming a cyclical or ring structure. Examples: cAMP, cGMP, c-di-GMP, etc.
http://purl.obolibrary.org/obo/UPa_UPA00760	cyclic nucleotide degradation	http://purl.obolibrary.org/obo/UPa_UPA00759	cyclic nucleotide metabolism		Degradation of cyclic nucleotides, any nucleotide in which the phosphate group is bonded to two of the sugar's hydroxyl groups, forming a cyclical or ring structure. Examples: cAMP, cGMP, c-di-GMP, etc.
http://purl.obolibrary.org/obo/UPa_UPA00761	purine nucleotide degradation	http://purl.obolibrary.org/obo/UPa_UPA00585	purine degradation		The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate moiety at either the 3' or 5'-hydroxyl group of its glycose moiety [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00765	ecdysteroid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00062	steroid biosynthesis		Biosynthesis of ecdysteroid compounds, a group of polyhydroxylated ketosteroids which initiate post-embryonic development. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00766	sterol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00622	alcohol biosynthesis		Biosynthesis of sterol compounds (steroid alcohols), a subgroup of steroids with a hydroxyl group in the 3-position of the A-ring.
http://purl.obolibrary.org/obo/UPa_UPA00769	estrogen biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00440	steroid hormone biosynthesis		Biosynthesis of estrogen (oestrogen) compounds, a group of steroid compounds, named for their importance in the estrous cycle, and functioning as the primary female sex hormone.
http://purl.obolibrary.org/obo/UPa_UPA00772	decaprenyl phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00751	phospholipid biosynthesis		Biosynthesis of decaprenyl phosphate, which plays a central role in the biosynthesis of most features of the mycobacterial cell wall, including peptidoglycan, linker unit galactan and arabinan.
http://purl.obolibrary.org/obo/UPa_UPA00773	epidermin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00471	lantibiotic A biosynthesis		Biosynthesis of epidermin, a type A lantibiotics that is is ribosomally synthesized and post-translationally modified. Extracellular proteolytic cleavage of the N-terminal leader region is most likely the last modification step in epidermin biosynthesis and leads to the activation of the lantibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00774	epothilone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of epothilone compounds, a class of macrolactone cytotoxic molecules, including epothilone A, epothilone B, and epothilone D, identified as potential chemotherapy drugs.
http://purl.obolibrary.org/obo/UPa_UPA00775	alkene degradation	http://purl.obolibrary.org/obo/UPa_UPA00777	alkene metabolism		Degradation of alkene compounds, unsaturated hydrcarbons containing at least one carbon-to-carbon double bond. Some bacteria, such as Xanthobacter autotrophicus Py2 and Rhodococcus rhodochrous, are capable of aerobic growth using aliphatic alkenes (such as ethylene, propylene and butylene) as source of carbon and energy.
http://purl.obolibrary.org/obo/UPa_UPA00776	propylene degradation	http://purl.obolibrary.org/obo/UPa_UPA00352	hydrocarbon degradation		Degradation of alkene compounds, unsaturated hydrcarbons containing at least one carbon-to-carbon double bond.
http://purl.obolibrary.org/obo/UPa_UPA00777	alkene metabolism	http://purl.obolibrary.org/obo/UPa_UPA00325	hydrocarbon metabolism		Metabolism of alkene compounds, unsaturated hydrocarbons containing at least one carbon-to-carbon double bond.
http://purl.obolibrary.org/obo/UPa_UPA00778	ethanol biosynthesis via fermentation pathway	http://purl.obolibrary.org/obo/UPa_UPA00779	ethanol metabolism		Biosynthesis of ethanol during fermentation processes.
http://purl.obolibrary.org/obo/UPa_UPA00779	ethanol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00611	alcohol metabolism		Metabolism of ethanol.
http://purl.obolibrary.org/obo/UPa_UPA00781	ether lipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00495	glycerolipid biosynthesis		Biosynthesis of ether lipid compounds. Ether lipids are lipids in which one or more of the carbon atoms on glycerol is bonded to an alkyl chain via an ether linkage, as opposed to the usual ester linkage.
http://purl.obolibrary.org/obo/UPa_UPA00782	Fe-Mo cofactor biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of Fe-Mo, the cofactor of nitrogenase (iron-molybdenum cofactor; FeMo-co). Fe-Mo cofactor is synthesized in a multistep process catalysed by several Nif proteins and is finally inserted into a pre-synthesized apo-dinitrogenase to generate mature dinitrogenase protein.
http://purl.obolibrary.org/obo/UPa_UPA00783	ferrichrome biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of siderophore ferrichrome.
http://purl.obolibrary.org/obo/UPa_UPA00785	melanin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00499	pigment biosynthesis		Biosynthesis of melanin, any of the polyacetylene, polyaniline, and polypyrrole 'blacks' and 'browns' or their mixed copolymers. The most common form of biological melanin is a polymer of either or both of two monomer molecules: indolequinone, and dihydroxyindole carboxylic acid. Melanin exists in the plant, animal and protista kingdoms, where it serves as a pigment. The presence of melanin in the archaea and bacteria kingdoms is still an issue.
http://purl.obolibrary.org/obo/UPa_UPA00786	sphingolipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00938	membrane lipid biosynthesis		Biosynthesis of sphingolipid compounds, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). There are three main types of sphingolipids: ceramides, sphingomyelins and glycosphingolipids.
http://purl.obolibrary.org/obo/UPa_UPA00787	galactosylceramide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00786	sphingolipid biosynthesis		Biosynthesis of the sphingolipid compounds: galactosylceramide (galactocerebroside).
http://purl.obolibrary.org/obo/UPa_UPA00788	glucocorticoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00440	steroid hormone biosynthesis		Biosynthesis of glucocorticoid compounds, a class of steroid hormones (corticosteroids) characterised by an ability to bind with the glucocorticoid receptor (GR).
http://purl.obolibrary.org/obo/UPa_UPA00789	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00632	teichoic acid biosynthesis		Biosynthesis of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.
http://purl.obolibrary.org/obo/UPa_UPA00790	poly(ribitol phosphate) teichoic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00632	teichoic acid biosynthesis		Biosynthesis of poly(ribitol phosphate) teichoic acid.
http://purl.obolibrary.org/obo/UPa_UPA00791	aldonic acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00858	carbohydrate acid degradation		Degradation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
http://purl.obolibrary.org/obo/UPa_UPA00792	D-gluconate degradation	http://purl.obolibrary.org/obo/UPa_UPA00791	aldonic acid degradation		Degradation of D-gluconic acid.
http://purl.obolibrary.org/obo/UPa_UPA00793	L-idonate degradation	http://purl.obolibrary.org/obo/UPa_UPA00791	aldonic acid degradation		Degradation of L-idonate. The pathway for catabolism of L-idonate, which proceeds via a D-gluconate intermediate, was originally thought to be gluconate utilization system GntII.
http://purl.obolibrary.org/obo/UPa_UPA00794	aldaric acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00858	carbohydrate acid degradation		Degradation of aldaric acids, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
http://purl.obolibrary.org/obo/UPa_UPA00795	glucosylglycerol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00615	glycerol metabolism		Biosynthesis of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.
http://purl.obolibrary.org/obo/UPa_UPA00798	zeaxanthin diglucoside biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis		Biosynthesis of zeaxanthin diglucoside, a glycosylated xantophyll carotenoid.
http://purl.obolibrary.org/obo/UPa_UPA00800	neurosporene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis		Biosynthesis of neurosporene, a carotene compound.
http://purl.obolibrary.org/obo/UPa_UPA00801	delta-carotene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis		Biosynthesis of delta-carotene, a cyclic carotene compound.
http://purl.obolibrary.org/obo/UPa_UPA00802	beta-carotene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis		Biosynthesis of beta-carotene, a cyclic carotene compound.
http://purl.obolibrary.org/obo/UPa_UPA00803	lycopene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis		Biosynthesis of lycopene, a bright red carotenoid pigment found in tomatoes and other red fruits.
http://purl.obolibrary.org/obo/UPa_UPA00804	alpha-zeacarotene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis		Biosynthesis of alpha-zeacarotene, a cyclic carotene compound.
http://purl.obolibrary.org/obo/UPa_UPA00805	beta-zeacarotene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis		Biosynthesis of beta-zeacarotene, a cyclic carotene compound.
http://purl.obolibrary.org/obo/UPa_UPA00810	D-xylose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of D-xylose, a naturally occurring plant polysaccharide.
http://purl.obolibrary.org/obo/UPa_UPA00811	Vi-antigen biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of Vi antigen, a capsular polysaccharide expressed by Salmonella typhi, the agent of human typhoid fever.
http://purl.obolibrary.org/obo/UPa_UPA00813	aldonic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00859	carbohydrate acid biosynthesis		Biosynthesis of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
http://purl.obolibrary.org/obo/UPa_UPA00816	dTDP-6-deoxy-L-altrose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of dTDP-6-deoxy-L-altrose, a nucleotide sugar.
http://purl.obolibrary.org/obo/UPa_UPA00817	dTDP-4-acetamido-4,6-dideoxygalactose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of dTDP-4-acetamido-4,6-dideoxygalactose (dTDP-D-Fuc4NAc), a nucleotide sugar.
http://purl.obolibrary.org/obo/UPa_UPA00818	CDP-ascarylose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of CDP-ascarylose, one of the naturally occurring 3,6-dideoxyhexoses usually confined to the cell wall lipopolysaccharide of gram-negative bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00819	spermidine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Metabolism of spermidine polyamine.
http://purl.obolibrary.org/obo/UPa_UPA00820	lacto-N-neotetraose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of lacto-N-neotetraose, an oligosaccharide found in the terminal position of lipooligosaccharide of Neisseria meningitidis.
http://purl.obolibrary.org/obo/UPa_UPA00821	exopolysaccharide EPS I biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00631	exopolysaccharide biosynthesis		Biosynthesis of exopolysaccharide EPS I.
http://purl.obolibrary.org/obo/UPa_UPA00824	salicylate degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of salicylic acid, an intermediate in degradation of phenol and naphtalene compounds.
http://purl.obolibrary.org/obo/UPa_UPA00826	spermine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00455	amine and polyamine metabolism		Metabolism of spermine by the addition of a propylamine moiety to spermidine.
http://purl.obolibrary.org/obo/UPa_UPA00827	poly(glycerol phosphate) teichoic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00632	teichoic acid biosynthesis		Biosynthesis of poly(glycerol phosphate) teichoic acid.
http://purl.obolibrary.org/obo/UPa_UPA00828	poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00632	teichoic acid biosynthesis		Biosynthesis of poly(glucosyl N-acetylgalactosamine 1-phosphate) teichoic acid.
http://purl.obolibrary.org/obo/UPa_UPA00829	quinol/quinone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA01055	quinol/quinone metabolism		Biosynthesis of quinol/quinone cofactors, such as menaquinone (vitamin K2), ubiquinone (coenzyme Q) or phylloquinone (vitamin K1).
http://purl.obolibrary.org/obo/UPa_UPA00831	protein ubiquitination (ubiquitin activation)	http://purl.obolibrary.org/obo/UPa_UPA00143	protein ubiquitination		The first step of the ubiquitination process. Ubiquitin is activated in a two-step reaction by an E1 ubiquitin-activating enzyme in a process requiring ATP as an energy source. The initial step involves production of a ubiquitin-adenylate intermediate. The second step transfers ubiquitin to the E1 active site cysteine residue, with release of AMP. This step results in a thioester linkage between the C-terminal carboxyl group of ubiquitin and the E1 cysteine sulfhydryl group. 2. Transfer of ubiquitin from E1 to the active site cysteine of a ubiquitin-conjugating enzyme E2 via a trans(thio)esterification reaction. 3. The final step of the ubiquitinylation cascade generally requires the activity of one of the hundreds of E3 ubiquitin-protein ligases (often termed simply ubiquitin ligase). E3 enzymes function as the substrate recognition modules of the system and are capable of interaction with both E2 and substrate. E3 enzymes possess one of two domains: * The HECT (Homologous to the E6-AP Carboxyl Terminus) domain * The RING domain (or the closely related U-box domain).
http://purl.obolibrary.org/obo/UPa_UPA00832	protein ubiquitination (E2 ubiquitin transfer)	http://purl.obolibrary.org/obo/UPa_UPA00143	protein ubiquitination		The second step of the ubiquitination process: transfer of ubiquitin from E1 to the active site cysteine of a ubiquitin-conjugating enzyme E2 via a trans(thio)esterification reaction.
http://purl.obolibrary.org/obo/UPa_UPA00833	protein ubiquitination (ubiquitin transfer)	http://purl.obolibrary.org/obo/UPa_UPA00143	protein ubiquitination		The final step of the ubiquitinylation cascade generally requires the activity of one of the hundreds of E3 ubiquitin-protein ligases (often termed simply ubiquitin ligase). E3 enzymes function as the substrate recognition modules of the system and are capable of interaction with both E2 and substrate. E3 enzymes possess one of two domains: * The HECT (Homologous to the E6-AP Carboxyl Terminus) domain * The RING domain (or the closely related U-box domain).
http://purl.obolibrary.org/obo/UPa_UPA00835	3-(3-hydroxyphenyl)propanoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00712	phenylpropanoid degradation		Degradation of 3-(3-hydroxyphenyl)propionic acid (3-HPP) into 3-(2,3-dihydroxyphenyl)propionic acid. 3-(2,3-dihydroxyphenyl)propionic acid is ultimately degraded to KREBS cycle intermediates. This pathway is common to 3-phenylpropionic acid degradation pathway, so it is recorded in a separate pathway.
http://purl.obolibrary.org/obo/UPa_UPA00836	3-(2,3-dihydroxyphenyl)propanoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00712	phenylpropanoid degradation		Degradation of 3-(2,3-dihydroxyphenyl)propionic acid to KREBS cycle intermediates.
http://purl.obolibrary.org/obo/UPa_UPA00837	melatonin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of melatonin (5-methoxy-N-acetyltryptamine), a naturally occurring hormone found in most animals and some of other living organisms, including algae.
http://purl.obolibrary.org/obo/UPa_UPA00838	amoeba cellulose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00693	cellulose biosynthesis		Biosynthesis of amoeba cellulose.
http://purl.obolibrary.org/obo/UPa_UPA00840	thiamine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00398	cofactor metabolism		Metabolism of thiamin (vitamin B1), a water soluble vitamin.
http://purl.obolibrary.org/obo/UPa_UPA00841	thiamine degradation	http://purl.obolibrary.org/obo/UPa_UPA00840	thiamine metabolism		Degradation of thiamin (vitamin B1), a water soluble vitamin.
http://purl.obolibrary.org/obo/UPa_UPA00842	taxol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00446	alkaloid biosynthesis		Biosynthesis of the diterpenoid taxol (generic name paclitaxel). Paclitaxel is a highly effective anticancer drug used widely in the treatment of various carcinomas, melanomas, and sarcomas. This structurally complex taxane diterpenoid (taxoid) was first isolated from the bark of the Pacific yew (Taxus brevifolia Nutt.).
http://purl.obolibrary.org/obo/UPa_UPA00843	zeaxanthin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis		Biosynthesis of zeaxanthin, one of the most common carotenoid alcohols found in nature. It is the pigment that gives corn, saffron, and many other plants their characteristic color.
http://purl.obolibrary.org/obo/UPa_UPA00844	teichuronic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00700	organic acid biosynthesis		Biosynthesis of teichuronic acid, a phosphate-free carbohydrate polymer containing glucuronic acid.
http://purl.obolibrary.org/obo/UPa_UPA00845	pectin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
http://purl.obolibrary.org/obo/UPa_UPA00847	pteridine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of pteridine derivative compounds, a group of heterocyclic compounds composed of fused pyrimidine and pyrazine rings. Pterins and flavins are classes of substituted pteridines that have important biological activity.
http://purl.obolibrary.org/obo/UPa_UPA00848	7,8-dihydroneopterin triphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00847	pteridine biosynthesis		Biosynthesis of dihydroneopterin triphosphate, the first committed intermediate in the biosynthetic pathways of tetrahydrofolate in plants and microorganisms and of tetrahydrobiopterin in animals.
http://purl.obolibrary.org/obo/UPa_UPA00849	tetrahydrobiopterin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00847	pteridine biosynthesis		Biosynthesis of tetrahydrobiopterin (sapropterin, BH4, H4-biopterin). Tetrahydrobiopterin is an essential cofactor of a set of enzymes that are of central metabolic importance, i.e. the hydroxylases of the three aromatic amino acids phenylalanine, tyrosine, and tryptophan, of ether lipid oxidase, and of the three nitric oxide synthase (NOS) isoenzymes. Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylases; phenylalanine-4-hydroxylase, tyrosine-3-hydroxylase and tryptophan-5-hydroxylase. Tetrahydrobiopterin is also essential for the synthesis of nitric oxide by nitric oxide synthase (NOS).
http://purl.obolibrary.org/obo/UPa_UPA00850	tetrahydrofolylpolyglutamate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00847	pteridine biosynthesis		Biosynthesis of tetrahydrofolylpolyglutamates, a group of folate derivative compounds comprising tetrahydrofolate attached to a chain of glutamate residues. In organisms that require exogenous folates for growth (Lactobacillus casei, Streptococcus faecalis, mammals), highly anionic polyglutamate chain of folate (four glutamate residues or more) retard transport through the cell membrane. This is the mechanism thought to be responsible for the accumulation and maintenance of cellular folate pools. cell membrane.
http://purl.obolibrary.org/obo/UPa_UPA00851	mitomycin C biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of mitomycin C, the first recognized bioreductive alkylating agent, widely used clinically for antitumor therapy. Mitomycinan are aziridine-containing natural products isolated from Streptomyces lavendulae.
http://purl.obolibrary.org/obo/UPa_UPA00852	morphine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00510	isoquinoline alkaloid biosynthesis		Biosynthesis of morphine, an isoquinolin alkaloid.
http://purl.obolibrary.org/obo/UPa_UPA00853	nisin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00470	lantibiotic biosynthesis		Biosynthesis of nisin, a 34-residue antibacterial peptide (lantibiotic family). Nisin is produced by several strains of Lactococcus lactis and strongly inhibits the growth of a broad range of gram-positive bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00854	nonprotein amino-acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of any amino-acid that does not normally occur as a constituent residue of proteins [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00855	nopaline degradation	http://purl.obolibrary.org/obo/UPa_UPA00854	nonprotein amino-acid degradation		Degradation of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.
http://purl.obolibrary.org/obo/UPa_UPA00856	2-dehydro-3-deoxy-D-gluconate degradation	http://purl.obolibrary.org/obo/UPa_UPA00791	aldonic acid degradation		Degradation of 2-dehydro-3-deoxy-D-gluconate, a product of pectin or galacturonate degradation.
http://purl.obolibrary.org/obo/UPa_UPA00857	carbohydrate acid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism		Metabolism of carbohydrate acid compounds.
http://purl.obolibrary.org/obo/UPa_UPA00858	carbohydrate acid degradation	http://purl.obolibrary.org/obo/UPa_UPA00857	carbohydrate acid metabolism		Degradation of carbohydrate acid compounds.
http://purl.obolibrary.org/obo/UPa_UPA00859	carbohydrate acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00857	carbohydrate acid metabolism		Biosynthesis of carbohydrate acid compounds.
http://purl.obolibrary.org/obo/UPa_UPA00860	glycosaminoglycan metabolism	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Metabolism of glycosaminoglycan compounds, any one of a group of polysaccharides that contain amino sugars.
http://purl.obolibrary.org/obo/UPa_UPA00861	glycosaminoglycan biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00860	glycosaminoglycan metabolism		Biosynthesis of glycosaminoglycan compounds, any one of a group of polysaccharides that contain amino sugars.
http://purl.obolibrary.org/obo/UPa_UPA00862	heparin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00861	glycosaminoglycan biosynthesis		Biosynthesis of heparin.
http://purl.obolibrary.org/obo/UPa_UPA00863	butanoate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00698	organic acid metabolism		Metabolism of butanoate (butyrate), a 4-carbon saturated monocarboxylic acid. This fatty acid occurs in the form of esters in animal fats and plant oils.
http://purl.obolibrary.org/obo/UPa_UPA00864	glycolate degradation	http://purl.obolibrary.org/obo/UPa_UPA00857	carbohydrate acid metabolism		Degradation of glycolic acid into 3-phospho-D-glyceric acid (an aldonic acid).
http://purl.obolibrary.org/obo/UPa_UPA00865	glycolate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00700	organic acid biosynthesis		Biosynthesis of glycolic acid (hydroxyacetic acid, hydroxyethanoic acid).
http://purl.obolibrary.org/obo/UPa_UPA00866	Ehrlich pathway	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Catabolism of branched-chain amino acids (leucine, valine, and isoleucine), aromatic amino acids (phenylalanine, tyrosine, and trytophan), and the sulfur-containing amino acid (methionine) leads to the formation of fusel acids and fusel alcohols.
http://purl.obolibrary.org/obo/UPa_UPA00867	L-lysine degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of L-lysine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00868	L-lysine degradation via saccharopine pathway	http://purl.obolibrary.org/obo/UPa_UPA00867	L-lysine degradation		The mitochondrial pathway of L-lysine degradation via saccharopine is the major mammalian pathway for lysine degradation.
http://purl.obolibrary.org/obo/UPa_UPA00869	L-lysine degradation via acetylation pathway	http://purl.obolibrary.org/obo/UPa_UPA00867	L-lysine degradation		Degradation of L-lysine via acetylation pathway. In this fungal pathway, L-lysine is degraded to glutarate via acetylation of the 6-amino group to the initial product N6-acetyl-L-lysine. This is followed by transamination, oxidative decarboxylation, deacetylation, transamination with loss of the second amino group, and oxidation to glutarate.
http://purl.obolibrary.org/obo/UPa_UPA00870	L-lysine degradation via acetate pathway	http://purl.obolibrary.org/obo/UPa_UPA00867	L-lysine degradation		UPC00047 fermentation process into acetate, butanoate and ammonia.
http://purl.obolibrary.org/obo/UPa_UPA00871	benzoxazinone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of benzoxazinone compounds. These cyclic hydroxamic acids are dedicated to pathogen defense and are found almost exclusively in Gramineae.
http://purl.obolibrary.org/obo/UPa_UPA00872	2,4-dihydroxy-1,4-benzoxazin-3-one biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00871	benzoxazinone biosynthesis		Biosynthesis of 2,4-dihydroxy-1,4-benzoxazin-3-one (DIBOA), a cyclic hydroxamic acid. This secondary metabolites found predominantly in Gramineae such as many maize (Zea mays).
http://purl.obolibrary.org/obo/UPa_UPA00873	(R)-mandelate degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of mandelic acid. This pathway provides the means to allow a variety of pseudomonads, including Pseudomonas putida, to use one or both enantiomers of mandelic acid as the sole carbon source.
http://purl.obolibrary.org/obo/UPa_UPA00874	HC-toxin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00478	mycotoxin biosynthesis		Biosynthesis of HC-toxin, a cyclic tetrapeptide of structure cyclo(D-Pro-L-Ala-D-Ala-L-Aeo), where Aeo stands for 2-amino-9,10-epoxi-8-oxodecanoic acid HC-toxin is an essential virulence determinant for the plant pathogenic fungus Cochliobolus carbonum and an inhibitor of histone deacetylase.
http://purl.obolibrary.org/obo/UPa_UPA00875	lovastatin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of lovastatin, an HMG-CoA reductase inhibitor produced by the fungus Aspergillus terreus. Lovastatin is composed of two polyketide chains.
http://purl.obolibrary.org/obo/UPa_UPA00876	leukotriene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00884	leukotriene metabolism		Biosynthesis of leukotrienes, eicosanoid lipid mediators derived from arachidonic acid.
http://purl.obolibrary.org/obo/UPa_UPA00877	leukotriene A4 biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00876	leukotriene biosynthesis		Biosynthesis of leukotriene A4 (LTA4).
http://purl.obolibrary.org/obo/UPa_UPA00878	leukotriene B4 biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00876	leukotriene biosynthesis		Biosynthesis of leukotriene B4 (LTB4).
http://purl.obolibrary.org/obo/UPa_UPA00879	leukotriene C4 biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00876	leukotriene biosynthesis		Biosynthesis of leukotriene C4 (LTC4).
http://purl.obolibrary.org/obo/UPa_UPA00880	leukotriene D4 biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00876	leukotriene biosynthesis		Biosynthesis of leukotriene D4 (LTD4).
http://purl.obolibrary.org/obo/UPa_UPA00881	hydroperoxy eicosatetraenoic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00383	arachidonate metabolism		Biosynthesis of hydroperoxy (e)icosatetraenoic acids (HPETEs), the primary products of lipoxygenase-catalysed oxygenation of arachidonic acid.
http://purl.obolibrary.org/obo/UPa_UPA00882	leukotriene degradation	http://purl.obolibrary.org/obo/UPa_UPA00884	leukotriene metabolism		Degradation of leukotrienes, eicosanoid lipid mediators derived from arachidonic acid.
http://purl.obolibrary.org/obo/UPa_UPA00883	leukotriene B4 degradation	http://purl.obolibrary.org/obo/UPa_UPA00882	leukotriene degradation		Degradation of leukotriene B4 (LTB4).
http://purl.obolibrary.org/obo/UPa_UPA00884	leukotriene metabolism	http://purl.obolibrary.org/obo/UPa_UPA00383	arachidonate metabolism		Metabolism of leukotrienes, eicosanoid lipid mediators derived from arachidonic acid.
http://purl.obolibrary.org/obo/UPa_UPA00885	protein neddylation	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
http://purl.obolibrary.org/obo/UPa_UPA00886	protein sumoylation	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Covalent modification of cellular proteins by the ubiquitin-like modifier SUMO. Protein sumoylation regulates various cellular processes, such as nuclear transport, signal transduction, stress response and cell-cycle progression.
http://purl.obolibrary.org/obo/UPa_UPA00887	auxin metabolism	http://purl.obolibrary.org/obo/UPa_UPA00437	plant hormone metabolism		Metabolism of auxins (indole-3-acetic acid, IAA), natural plant hormones involved in several stages of plant growth and development such as cell elongation, cell division, tissue differentiation, and apical dominance.
http://purl.obolibrary.org/obo/UPa_UPA00888	limonene degradation	http://purl.obolibrary.org/obo/UPa_UPA00137	monoterpene degradation		Degradation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. Limonene is the most widespread terpene in the world and is formed by more than 300 plants.
http://purl.obolibrary.org/obo/UPa_UPA00889	melamine degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of melamine (1,3,5-triazine-2,4,6-triamine). Melamine is a metabolite of cyromazine, a pesticide. It is formed in the body of mammals who have ingested cyromazine. It was also reported that cyromazine is converted to melamine in plants.
http://purl.obolibrary.org/obo/UPa_UPA00890	secondary metabolite degradation	http://purl.obolibrary.org/obo/UPa_UPA00465	secondary metabolite metabolism		Degradation of secondary metabolites.
http://purl.obolibrary.org/obo/UPa_UPA00891	lignin metabolism	http://purl.obolibrary.org/obo/UPa_UPA00710	phenylpropanoid metabolism		Metabolism of lignin, a class of polymers of phenylpropanoid units.
http://purl.obolibrary.org/obo/UPa_UPA00892	lignin degradation	http://purl.obolibrary.org/obo/UPa_UPA00891	lignin metabolism		Degradation of lignin, a class of polymers of phenylpropanoid units.
http://purl.obolibrary.org/obo/UPa_UPA00893	lignin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00891	lignin metabolism		Biosynthesis of lignin, a class of polymers of phenylpropanoid units.
http://purl.obolibrary.org/obo/UPa_UPA00894	diglucosyl-diacylglycerol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of diglucosyl-diacylglycerol, a component of membrane glycolipids.
http://purl.obolibrary.org/obo/UPa_UPA00895	methylamine degradation	http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism		Degradation of methylamine into formaldehyde (methanal).
http://purl.obolibrary.org/obo/UPa_UPA00896	(S)-3-hydroxy-3-methylglutaryl-CoA degradation	http://purl.obolibrary.org/obo/UPa_UPA00498	metabolic intermediate degradation		Degradation of HMG-CoA ((S)-3-hydroxy-3-methylglutaryl-CoA) into acetoacetic acid. HMG-CoA is an intermediate in the mevalonic acid and leucine degradation pathways.
http://purl.obolibrary.org/obo/UPa_UPA00897	isoflavonoid phytoalexin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00421	phytoalexin biosynthesis		Biosynthesis of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00898	glyceollin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00897	isoflavonoid phytoalexin biosynthesis		Biosynthesis of glyceollins. The glyceollins belong to the isoflavonoid phytoalexins.
http://purl.obolibrary.org/obo/UPa_UPA00899	phenylpropanoid phytoalexin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00711	phenylpropanoid biosynthesis		Biosynthesis of phenylpropanoid phytoalexins.
http://purl.obolibrary.org/obo/UPa_UPA00900	methoxydianthramide B biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00899	phenylpropanoid phytoalexin biosynthesis		Biosynthesis of methoxydianthramide B (N-benzoyl-4-O-methoxyanthranilate), a phenylpropanoid phytoalexin.
http://purl.obolibrary.org/obo/UPa_UPA00901	pterocarpan phytoalexin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00897	isoflavonoid phytoalexin biosynthesis		Biosynthesis of pterocarpan phytoalexins (medicarpin and maackian).
http://purl.obolibrary.org/obo/UPa_UPA00902	medicarpin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00901	pterocarpan phytoalexin biosynthesis		Biosynthesis of medicarpin, the major phytoalexin in alfalfa. Medicarpin is synthesized via the isoflavonoid branch of phenylpropanoid metabolism.
http://purl.obolibrary.org/obo/UPa_UPA00903	L-methionine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of sulfur-containing amino-acid L-methionine (2-amino-4-(methylthio)butanoic acid). L-methionine is an essential amino-acid for many crucial cellular functions, including the initiation of protein synthesis, methylation of DNA and rRNA, and biosynthesis of cysteine, phospholipids and polyamines.
http://purl.obolibrary.org/obo/UPa_UPA00904	L-methionine biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00903	L-methionine biosynthesis		The methionine salvage pathway (MSP) is an important metabolic pathway in maintaining the amount of L-methionine as the amount of methionine in cells is typically limiting and its de novo biosynthesis is energetically expensive. Therefore, L-methionine is salvaged from S-methyl-5'-thioadenosine (MTA), the end-product of spermidine biosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00905	aminoacyl-tRNA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification		Biosynthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase.
http://purl.obolibrary.org/obo/UPa_UPA00906	selenocysteinyl-tRNA(Sec) biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00905	aminoacyl-tRNA biosynthesis		Biosynthesis of selenocysteinyl-tRNA(Sec). If the pathway for selenocysteine biosynthesis differs in bacteria from that present in eukaryotes and archaea; tRNA(Sec) remains a common factor for selenocysteine formation among the three kingdoms.
http://purl.obolibrary.org/obo/UPa_UPA00907	2-deoxystreptamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of 2-deoxystreptamine (DOS).
http://purl.obolibrary.org/obo/UPa_UPA00908	ppGpp biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00488	purine nucleotide biosynthesis		Biosynthesis of ppGpp (guanosine tetraphosphate, guanosine 5'-diphosphate 3'-diphosphate), a derivative of guanine riboside. The stringent response to amino acid starvation, whereby stable RNA synthesis is curtailed in favour of transcription of amino acid biosynthetic genes, is controlled by the alarmone ppGpp.
http://purl.obolibrary.org/obo/UPa_UPA00909	GMP biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00584	purine biosynthesis		GMP biosynthesis from guanine (salvage pathway).
http://purl.obolibrary.org/obo/UPa_UPA00910	sulfatase oxidation	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Maturation of sulfatase through oxidation of a specific cysteine to Calpha-formylglycine (Fgly), a catalytic residue in their active site.
http://purl.obolibrary.org/obo/UPa_UPA00911	retinoid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00913	isoprenoid metabolism		Metabolism of retinoids, a class of chemical compounds that are related chemically to vitamin A. Retinoids have many important and diverse functions throughout the body including roles in vision, regulation of cell proliferation and differentiation, growth of bone tissue, immune function, and activation of tumor suppressor genes.
http://purl.obolibrary.org/obo/UPa_UPA00912	retinol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00913	isoprenoid metabolism		Metabolism of retinol, the animal form of vitamin A. Retinol is a fat-soluble vitamin important in vision and bone growth. It belongs to the family of chemical compounds known as retinoids.
http://purl.obolibrary.org/obo/UPa_UPA00913	isoprenoid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues. [source: GO] Isoprene is the chemical 2-methyl-1,3-butadiene. It is a common structural motif in biological systems. The terpenes (for example, the carotenes are tetraterpenes) are derived from isoprene, as are the terpenoids and coenzyme Q. Also derived from isoprene are phytol, retinol (vitamin A) , tocopherol (vitamin E), dolichols, and squalene. Heme A has an isoprenoid tail, and lanosterol, the sterol precursor in animals, is derived from squalene and hence from isoprene. The functional isoprene units in biological systems are dimethylallyl pyrophosphate (DMAPP) and its isomer isopentenyl pyrophosphate (IPP), which are used in the biosynthesis of terpenes and lanosterol derivatives.
http://purl.obolibrary.org/obo/UPa_UPA00914	myo-inositol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00613	polyol metabolism		Metabolism of myo-inositol (cis-1,2,3,5-trans-4,6-cyclohexanehexol), arbocyclic polyol that plays an important role as the structural basis for a number of secondary messengers in eukaryotic cells, including inositol phosphates, phosphatidylinositol (PI) and phosphatidylinositol phosphate (PIP) lipids.
http://purl.obolibrary.org/obo/UPa_UPA00915	mycolic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00420	lipid biosynthesis		Biosynthesis of mycolic acids. Mycolic acids are essential elements of the mycobacterial envelope.
http://purl.obolibrary.org/obo/UPa_UPA00916	D-ribose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of D-ribose carbohydrate. D-ribose, which can serve as a total source of carbon and energy for E. coli, enters the cell via a high-affinity ABC transport system and hence in unphosphorylated form. The ribose ABC transporter facilitates transport of beta-D-ribopyranose. which is converted to furanose forms of beta-D-ribose. Interconversion of the alpha- and beta-anomers of D-ribofuranose is fast and spontaneous. It is then converted to D-ribose-5-phosphate, an intermediate of the pentose phosphate pathway.
http://purl.obolibrary.org/obo/UPa_UPA00917	poly-(R)-3-hydroxybutanoate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00320	biopolymer biosynthesis		Biosynthesis of poly-(R)-3-hydroxybutyric acid (PHB), a homopolymer of D-(-)-3-hydroxybutyrate that belongs to a family of naturally occurring, biodegradable polyesters, known as polyhydroxyalkanoates (PHA). PHB is a storage material produced by a variety of bacteria in response to environmental stress. PHA act as reserve compounds for carbon, energy, and reducing equivalents and are of interest because their material properties make them a potential alternative to some petroleum-based thermoplastics.
http://purl.obolibrary.org/obo/UPa_UPA00918	patulin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00478	mycotoxin biosynthesis		Biosynthesis of patulin, a mycotoxin produced by 14 species of the genus Penicillium and is most likely to be found in fruits, silage and dung. Patulin is also an antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00919	2-oxosuberate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00700	organic acid biosynthesis		Biosynthesis of 2-oxosuberate (alpha-ketosuberate), a precursor to coenzyme B (7-mercaptoheptanoylthreonine phosphate) and biotin.
http://purl.obolibrary.org/obo/UPa_UPA00920	pyruvate fermentation	http://purl.obolibrary.org/obo/UPa_UPA00699	organic acid degradation		Conversion of pyruvate (the final product of glycolysis) to formic acid in the absence of oxygen.
http://purl.obolibrary.org/obo/UPa_UPA00921	mRNA processing	http://purl.obolibrary.org/obo/UPa_UPA00480	RNA modification		Conversion of a primary mRNA transcript into one or more functional mRNA(s). This includes 5' capping, 3' cleavage and polyadenylation, as well as mRNA splicing and RNA editing.
http://purl.obolibrary.org/obo/UPa_UPA00922	mRNA capping	http://purl.obolibrary.org/obo/UPa_UPA00921	mRNA processing		The 5' ends of most eukaryotic mRNAs and many viral mRNAs harbor a m7GpppN cap structure that plays a critical role in the translation and stability of mRNAs. Biosynthesis of this cap structure involves three distinct enzymatic activities: (i) the 5' end of pre-mRNAs is initially hydrolyzed to a diphosphate end by an RNA triphosphatase; (ii) the diphosphate end of the mRNA is then capped with GMP by an RNA guanylyltransferase, and finally, (iii) the cap is methylated by an RNA (guanine-7) methyltransferase. Addition of the 7-methylguanosine cap to the 5' end of a eukaryotic mRNA transcript.
http://purl.obolibrary.org/obo/UPa_UPA00923	nitrobenzene degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of nitrobenzene. Pseudomonas pseudoalcaligenes JS45 utilizes nitrobenzene as the sole source of nitrogen, carbon, and energy. Some studies have shown that degradation of nitrobenzene involves the reduction of nitrobenzene to nitrosobenzene and hydroxylaminobenzene, followed by rearrangement to 2-aminophenol, which then undergoes meta ring cleavage to 2-aminomuconic semialdehyde. Comamonas sp. JS765 can also use nitrobenzene as the sole source of carbon, nitrogen, and energy. It inserts dioxygen directly into nitrobenzene, with concomitant reduction of the substrate to form catechol.
http://purl.obolibrary.org/obo/UPa_UPA00924	oleoresin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00448	terpene biosynthesis		Biosynthesis of oleoresin, a complex mixture of mono-, sesqui-, and diterpenoids that accumulates at the wound site to kill invaders and both flush and seal the injury.
http://purl.obolibrary.org/obo/UPa_UPA00925	stachyose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
http://purl.obolibrary.org/obo/UPa_UPA00926	oxytetracycline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of oxytetracycline, an acetate-derived polyketide antibiotic that belongs to the broad-spectrum tetracycline group.
http://purl.obolibrary.org/obo/UPa_UPA00927	formaldehyde assimilation via serine pathway	http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism		The serine cycle for formaldehyde assimilation (QSC) is the main assimilatory pathway for methylotrophic growth.
http://purl.obolibrary.org/obo/UPa_UPA00928	methanol degradation	http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism		Conversion of methanol into forrmaldehyde.
http://purl.obolibrary.org/obo/UPa_UPA00929	succinyl-CoA degradation	http://purl.obolibrary.org/obo/UPa_UPA00410	ketone degradation		Degradation of succinyl-CoA into acetoacetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UPA00930	phenylacetate degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of phenylacetic acid (PAA, benzeneacetic acid), an organic compound containing a phenyl functional group and an acetic acid functional group. Phenylacetic acid is a common source of carbon and energy for a wide variety of microorganisms.
http://purl.obolibrary.org/obo/UPa_UPA00931	cellular component biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Biogenesis of cellular components.
http://purl.obolibrary.org/obo/UPa_UPA00932	cell surface structure biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00931	cellular component biogenesis		Biogenesis of extracellular cell structures: fimbrae, pili, S-layers, capsules and slime layers.
http://purl.obolibrary.org/obo/UPa_UPA00933	capsule biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00932	cell surface structure biogenesis		Formation, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi.
http://purl.obolibrary.org/obo/UPa_UPA00934	capsule polysaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00933	capsule biogenesis		Biosynthesis of polysaccharides that make up the capsule, a mucopolysaccharide protective structure surrounding some species of bacteria and fungi.
http://purl.obolibrary.org/obo/UPa_UPA00935	slime biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00932	cell surface structure biogenesis		Biosynthesis of slime layer envelopping the cell.
http://purl.obolibrary.org/obo/UPa_UPA00936	slime polysaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00935	slime biogenesis		Biosynthesis of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall.
http://purl.obolibrary.org/obo/UPa_UPA00937	p-cumate degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of p-cumic acid, an aromatic hydrocarbon compound.
http://purl.obolibrary.org/obo/UPa_UPA00938	membrane lipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00939	membrane lipid metabolism		Biosynthesis of membrane lipids, any lipid found in or associated with a biological membrane.
http://purl.obolibrary.org/obo/UPa_UPA00939	membrane lipid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00436	lipid metabolism		Metabolism of membrane lipids, any lipid found in or associated with a biological membrane.
http://purl.obolibrary.org/obo/UPa_UPA00940	glycerophospholipid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00939	membrane lipid metabolism		Metabolism of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
http://purl.obolibrary.org/obo/UPa_UPA00941	N-acetylgalactosamine degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of N-acetylgalactosamine.
http://purl.obolibrary.org/obo/UPa_UPA00942	biological regulation	http://purl.obolibrary.org/obo/UPa_UPA00001	biological process		Any process that modulates the frequency, rate or extent of any biological process, quality or function. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00943	signal transduction	http://purl.obolibrary.org/obo/UPa_UPA00942	biological regulation		Signal transduction refers to any process by which a cell converts one kind of signal or stimulus into another. Most processes of signal transduction involve ordered sequences of biochemical reactions inside the cell, which are carried out by enzymes, activated by second messengers, resulting in a signal transduction pathway.
http://purl.obolibrary.org/obo/UPa_UPA00944	phosphatidylinositol signaling pathway	http://purl.obolibrary.org/obo/UPa_UPA00943	signal transduction		Phosphatidylinositol is the substrate for a large number of enzymes which are involved in cell signaling because it can be phosphorylated by a variety of kinases on the hydroxyl groups 3, 4 and 5 on the inositol ring in seven different combinations.
http://purl.obolibrary.org/obo/UPa_UPA00945	propanoyl-CoA degradation	http://purl.obolibrary.org/obo/UPa_UPA00498	metabolic intermediate degradation		Degradation of propionyl-CoA.
http://purl.obolibrary.org/obo/UPa_UPA00946	propanoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00699	organic acid degradation		Degradation of propionic acid, an organic acid.
http://purl.obolibrary.org/obo/UPa_UPA00947	glycerophospholipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00938	membrane lipid biosynthesis		Biosynthesis of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
http://purl.obolibrary.org/obo/UPa_UPA00948	phosphatidylserine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00947	glycerophospholipid biosynthesis		Biosynthesis of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00949	phosphatidylinositol metabolism	http://purl.obolibrary.org/obo/UPa_UPA00940	glycerophospholipid metabolism		Metabolism of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol. [source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00950	spore coat biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00932	cell surface structure biogenesis		Biogenesis of spore coat, a complex multiprotein structure that plays an important role in spore germination and resistance to toxic chemicals. Other functions are assigned to the coat, from sensing the external environment through active enzymes present on its surface to protecting the spore from predation by phagocytic protozoans. In addition, the coat is a novel system for the display at the spore surface of heterologous antigens, enzymes, and bioactive molecules.
http://purl.obolibrary.org/obo/UPa_UPA00951	photorespiration	http://purl.obolibrary.org/obo/UPa_UPA00091	photosynthesis		Photorespiration involves three organelles: the chloroplast, the peroxisome, and the mitochondria. At conditions of low CO2 concentration and high O2 concentration, ribulose bisphosphate is oxidized to 3-phosphoglycerate and 2-phosphoglycolate. The two-carbon molecule, 2-phosphoglycolate is converted to glycine. The decarboxylation of two glycines generates serine, CO2 and NH3. Serine is further converted to 3-phosphoglycerate. 3-phosphoglycerate generated from photorespiration re-enters the CO2 fixation Calvin cycle. NH3 is re-fixed by glutamine synthetase. The outcome of photorespiration is loss of CO2 and energy in photosynthetic cells. The biological function of photorespiration is not clear. One possibility is that photorespiration is necessary under conditions of high light intensity and low CO2 concentration (i.e. when stomata is closed under water stress) to dissipate excess ATP and reducing power from the photosynthesis light reactions, thus to prevent damage to the photosynthetic apparatus. [MetaCyc].
http://purl.obolibrary.org/obo/UPa_UPA00952	proanthocyanidin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00154	flavonoid biosynthesis		Biosynthesis of proanthocyanidins (oligomeric proanthocyanidins or OPCs), a class of flavonoid complexes found in sea buckthorn oil and grape seeds and skin. Proanthocyanidin act as antioxidants (free radical scavengers) in the human body.
http://purl.obolibrary.org/obo/UPa_UPA00953	spore coat polysaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00950	spore coat biogenesis		Biosynthesis of spore coat polysaccharides.
http://purl.obolibrary.org/obo/UPa_UPA00954	vitamin D biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00435	hormone biosynthesis		Biosynthesis of vitamin D, a group of fat-soluble prohormones, the two major forms of which are vitamin D2 (or ergocalciferol) and vitamin D3 (or cholecalciferol). The term vitamin D also refers to metabolites and other analogues of these substances. Vitamin D3 is produced in skin exposed to sunlight, specifically ultraviolet B radiation.
http://purl.obolibrary.org/obo/UPa_UPA00955	cholecalciferol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00954	vitamin D biosynthesis		Biosynthesis of cholecalciferol (vitamin D3).
http://purl.obolibrary.org/obo/UPa_UPA00956	L-fucose metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of the methylpentose L-fucose (6-deoxygalactose).
http://purl.obolibrary.org/obo/UPa_UPA00957	N-glycan metabolism	http://purl.obolibrary.org/obo/UPa_UPA00441	glycan metabolism		Metabolism of asparagine (N)-linked oligosaccharides (N-glycans).
http://purl.obolibrary.org/obo/UPa_UPA00958	LPS core biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00030	lipopolysaccharide biosynthesis		Biosynthesis of the core region of bacterial lipopolysaccharides (LPS).
http://purl.obolibrary.org/obo/UPa_UPA00959	phosphorus metabolism	http://purl.obolibrary.org/obo/UPa_UPA00026	metabolism		Metabolic pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus.[source: GO].
http://purl.obolibrary.org/obo/UPa_UPA00960	phosphonate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00959	phosphorus metabolism		Biosynthesis of phosphonates, i.e organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups.
http://purl.obolibrary.org/obo/UPa_UPA00961	ginkgolide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00423	terpene metabolism		Biosynthesis of ginkgolide derivatives, biologically active terpenic lactones present in Ginkgo biloba. Ginkgolides have a diterpenoid structure, i.e. it has 20-carbon skeleton and are synthesized from geranylgeranyl pyrophosphate.
http://purl.obolibrary.org/obo/UPa_UPA00962	L-cysteine metabolism	http://purl.obolibrary.org/obo/UPa_UPA00401	amino-acid metabolism		Metabolism of L-cysteine (2-amino-3-mercaptopropanoic acid) , an hydrophilic natural amino-acids with a thiol sidechain.
http://purl.obolibrary.org/obo/UPa_UPA00963	cell wall polysaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00547	cell wall biogenesis		Biosynthesis of polysaccharides that make up the cell wall.
http://purl.obolibrary.org/obo/UPa_UPA00964	butirosin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of butirosin, a water-soluble aminoglycosidic antibiotic complex isolated from fermentation filtrates of bacillus circulans.
http://purl.obolibrary.org/obo/UPa_UPA00965	kanamycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of kanamycin, an aminoglycoside antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of aminoglycoside, a group of antibiotics active against many aerobic gram-negative and some gram-positive bacteria. Aminoglycoside are mostly produced by fungi and contain an amino sugar, and amino-or guanido-substituted inositol ring which are attached by a glycosidic linkage to a hexose nucleus resulting in a polycationic and highly polar compound. T Common examples are streptomycin, gentamicin, amikacin, kanamycin, tobramycin, netilmicin, neomycin, framycetin.
http://purl.obolibrary.org/obo/UPa_UPA00967	gentamicin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of gentamicin, an aminoglycoside antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00968	lividomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of lividomycin, an aminoglycoside antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00969	neomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of neomycin, an aminoglycoside antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00970	paromomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of paromomycin, an aminoglycoside antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00971	tobramycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of tobramycin, an aminoglycoside antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00972	ribostamycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00966	aminoglycoside antibiotic biosynthesis		Biosynthesis of ribostamycin, an aminoglycoside antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA00973	LPS lipid A biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of lipid A, the glycolipid moiety of bacterial lipopolysaccharides, consisting of six fatty acyl chains linked to two glucosamine residues.
http://purl.obolibrary.org/obo/UPa_UPA00974	pentalenolactone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of pentalenolactone, a sesquiterpenoid antibiotic, first isolated in 1957 from Streptomyces roseogriseus and subsequently found in the extracts of numerous Streptomyces species. Pentalenolactone has been shown to be active against both Gram-positive and Gram-negative bacteria as well as a variety of fungi and protozoa and to inhibit the replication of DNA viruses such as HSV-1 and HSV-2. Pentalenolactone also inhibits vascular smooth muscle cell proliferation.
http://purl.obolibrary.org/obo/UPa_UPA00975	prenylquinone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00829	quinol/quinone biosynthesis		Biosynthesis of prenylquinone, a group of benzoquinone (ubiquinone, plastoquinone) with isoprenyl side chain.
http://purl.obolibrary.org/obo/UPa_UPA00976	LOS core biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00501	lipooligosaccharide biosynthesis		Biosynthesis of the core region of bacterial lipoolidosaccharides (LOS).
http://purl.obolibrary.org/obo/UPa_UPA00977	S-layer biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00932	cell surface structure biogenesis		Biogenesis of S-layer structure, a crystalline protein layer surrounding some bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00978	flagellum biogenesis	http://purl.obolibrary.org/obo/UPa_UPA00932	cell surface structure biogenesis		Biogenesis (formation and assembly) of flagellum components. In bacteria, this is a whiplike motility appendage present on the surface of some species; in eukaryotes, flagella are threadlike protoplasmic extensions used to propel flagellates and sperm. Flagella are composed of flagellin and have the same basic structure as cilia but are longer .
http://purl.obolibrary.org/obo/UPa_UPA00979	calcium-dependent antibiotic biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of the calcium-dependent antibiotics (CDAs). CDAs belong to the group of structurally related acidic lipopetide antibiotics, which include A54145, daptomycin, friulimicins and amphomycins. All of these nonribosomally biosynthesized lipopeptides contain N-terminal fatty acid side chains, which is a trans-2,3-epoxyhexanoyl moiety in the case of CDA, along with decapeptide lactone or lactam cores.
http://purl.obolibrary.org/obo/UPa_UPA00980	colanic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00631	exopolysaccharide biosynthesis		Biosynthesis of colanic acid (M-antigen), an exopolysaccharide common to many enterobacteria.
http://purl.obolibrary.org/obo/UPa_UPA00981	quinolobactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of quinolobactin (8-hydroxy-4-methoxy-quinaldic acid), a siderophore produced by some pseudomonas species.
http://purl.obolibrary.org/obo/UPa_UPA00982	limonene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00717	monoterpene biosynthesis		Biosynthesis of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene. Limonene is the most widespread terpene in the world and is formed by more than 300 plants.
http://purl.obolibrary.org/obo/UPa_UPA00983	(4R)-limonene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00982	limonene biosynthesis		Biosynthesis of D-limonene ((+)-4R-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
http://purl.obolibrary.org/obo/UPa_UPA00984	(4S)-limonene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00982	limonene biosynthesis		Biosynthesis of L-limonene ((-)-4S-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
http://purl.obolibrary.org/obo/UPa_UPA00985	(-)-alpha-pinene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00717	monoterpene biosynthesis		Biosynthesis of (-)-alpha-pinene ((1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene), a bicyclic monoterpene. It is produced from geranyl pyrophosphate, via cyclisation of linaloyl pyrophosphate followed by loss of a proton from the carbocation equivalent.
http://purl.obolibrary.org/obo/UPa_UPA00986	(-)-beta-pinene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00717	monoterpene biosynthesis		It is produced from geranyl pyrophosphate, via cyclisation of linaloyl pyrophosphate followed by loss of a proton from the carbocation equivalent.
http://purl.obolibrary.org/obo/UPa_UPA00987	(4R)-limonene degradation	http://purl.obolibrary.org/obo/UPa_UPA00888	limonene degradation		Degradation of (4R)-limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
http://purl.obolibrary.org/obo/UPa_UPA00988	5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification		Biosynthesis of 5-methoxycarbonylmethyl-2-thiouridine-tRNA. The wobble modification, 5-methoxycarbonylmethyl-2-thiouridine (mcm5s2U), is required for the proper decoding of NNR codons in eukaryotes.
http://purl.obolibrary.org/obo/UPa_UPA00989	N(7)-methylguanine-tRNA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00481	tRNA modification		Biosynthesis of N(7)-methylguanine-tRNA. 7-methylguanosine (m7G) modification of tRNA occurs widely in eukaryotes and bacteria, is nearly always found at position 46, and is one of the few modifications that confers a positive charge to the base.
http://purl.obolibrary.org/obo/UPa_UPA00990	L-ascorbate biosynthesis via GDP-alpha-D-mannose pathway	http://purl.obolibrary.org/obo/UPa_UPA00132	L-ascorbate biosynthesis		Biosynthesis of L-ascorbic acid from GDP-D-mannose.
http://purl.obolibrary.org/obo/UPa_UPA00991	L-ascorbate biosynthesis via UDP-alpha-D-glucuronate pathway	http://purl.obolibrary.org/obo/UPa_UPA00132	L-ascorbate biosynthesis		Biosynthesis of L-ascorbic acid from UDP-glucuronic acid. This pathway occurs in most vertebrates, although not in guinea pigs and primates, including humans.
http://purl.obolibrary.org/obo/UPa_UPA00992	endocannabinoid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00435	hormone biosynthesis		Biosynthesis of endocannabinoid derivatives. Endocannabinoid are endogenous compounds that bind to cannabinoid receptors (cannabimimetic activity). They are structurally different from the cannabinoids which are primarily derived from plants.
http://purl.obolibrary.org/obo/UPa_UPA00993	2-arachidonoylglycerol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00992	endocannabinoid biosynthesis		Biosynthesis of 2-arachidonoylglycerol (2-AG), an endogenous lipid that activates brain canabinoid receptors. 2-arachidonoylglycerol is an endocannabinoid. There are two possible routes of 2-AG biosynthesis in neurons [PMID:12843414]. Phospholipase C (PLC)-mediated hydrolysis of membrane phospholipids may produce 1,2-diacylglycerol, which may be subsequently converted to 2-arachidonoylglycerol by diacylglycerol lipase (DGL) activity. Alternatively, phospholipase A1 (PLA1) may generate a lysophospholipid, which may be hydrolyzed to 2-arachidonoylglycerol by a lyso-PLC activity.
http://purl.obolibrary.org/obo/UPa_UPA00995	phylloquinone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00829	quinol/quinone biosynthesis		Biosynthesis of phylloquinone (also called vitamine K1 or phytonadione), a lipid-soluble molecule that belongs to the naphto-quinone family.
http://purl.obolibrary.org/obo/UPa_UPA00996	carbamoyl phosphate degradation	http://purl.obolibrary.org/obo/UPa_UPA00498	metabolic intermediate degradation		Degradation of carbamoyl phosphate, a key metabolic intermediate.
http://purl.obolibrary.org/obo/UPa_UPA00997	proteasomal Pup-dependent pathway	http://purl.obolibrary.org/obo/UPa_UPA00468	protein degradation		Degradation of proteins by hydrolysis of their peptide bonds. This process is initiated by the covalent attachment of pup (Prokaryotic Ubiquitin-like Protein), and mediated by the proteasome.
http://purl.obolibrary.org/obo/UPa_UPA00998	protein pupylation	http://purl.obolibrary.org/obo/UPa_UPA00460	protein modification		Conjugation of pup (Prokaryotic Ubiquitin-like Protein) to a target protein via an isopeptide bond between the carboxyl terminus of pup and the epsilon-amino group of a lysine residue of the target protein.
http://purl.obolibrary.org/obo/UPa_UPA01000	tetrahydrofolate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00496	metabolic intermediate metabolism		Metabolism of tetrahydrofolate derivative compounds.
http://purl.obolibrary.org/obo/UPa_UPA01001	bacilysocin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of bacilysocin, a phospholipid antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA01002	polychlorinated biphenyl degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of polychlorinated biphenyls xenobiotic compounds.
http://purl.obolibrary.org/obo/UPa_UPA01003	bacillaene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of bacillaene, a polyketide antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA01004	palatinose degradation	http://purl.obolibrary.org/obo/UPa_UPA00442	glycan degradation		Degradation of palatinose.
http://purl.obolibrary.org/obo/UPa_UPA01005	petrobactin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00302	siderophore biosynthesis		Biosynthesis of petrobactin, a catecholate siderophore that functions in both iron acquisition and virulence in a murine model of anthrax. Petrobactin harbors unique 3,4-dihydroxybenzoyl iron-liganding groups.
http://purl.obolibrary.org/obo/UPa_UPA01006	mannosylfructose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA01008	oligosaccharide biosynthesis		Biosynthesis of mannosylfructose. This disaccharide has been first discovered as the major osmolyte in salt-tolerant strains of A.tumefaciens biotype I.
http://purl.obolibrary.org/obo/UPa_UPA01007	oligosaccharide metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages [GO:0009311].
http://purl.obolibrary.org/obo/UPa_UPA01008	oligosaccharide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA01007	oligosaccharide metabolism		Biosynthesis of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages [GO:0009312].
http://purl.obolibrary.org/obo/UPa_UPA01010	nicotinate degradation	http://purl.obolibrary.org/obo/UPa_UPA01009	nicotinate metabolism		Degradation of nicotinate also known as niacin or vitamin B3, a water-soluble vitamin.
http://purl.obolibrary.org/obo/UPa_UPA01011	4-chlorobenzoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of 4-chlorobenzoate (4-CBA) by certain soil bacteria. 4-chlorobenzoate is not known to be a natural product but is introduced in the environement through its use as a precursor in the synthesis of dye stuffs, pigments and pharmaceuticals.
http://purl.obolibrary.org/obo/UPa_UPA01012	L-aspartate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-aspartate amino-acid from oxaloacetate, an intermediate of the TCA cycle, by a transamination reaction with glutamate. L-aspartate is a constituent of proteins and participates in several other biosyntheses as purine and pyrimidine nucleotide, NAD, phosphopanthothenate and other amino acids.
http://purl.obolibrary.org/obo/UPa_UPA01013	L-glutamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-glutamine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA01014	ergothioneine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00521	organosulfur biosynthesis		Biosynthesis of ergothioneine. Ergothioneine is a histidine-derived thiol of bacterial and fungal origin that has also been isolated from animal and human tissue. Ergothioneine has antioxidant properties.
http://purl.obolibrary.org/obo/UPa_UPA01015	anthranilate degradation	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Degradation of anthranilate (2-aminobenzoate). Anthranilate is an intermediate in the degradation of many compounds, such as tryptophan, o-nitrobenzoate, quinaldine, carbazole, and those containing an indole moiety.
http://purl.obolibrary.org/obo/UPa_UPA01016	anthranilate degradation via hydroxylation	http://purl.obolibrary.org/obo/UPa_UPA01015	anthranilate degradation		Degradation of anthranilate via hydroxylation pathway. This aerobic pathway converts anthranilate to catechol in a single step.
http://purl.obolibrary.org/obo/UPa_UPA01017	xanthan biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of xanthan, an industrially important exopolysaccharide produced by the phytopathogenic, gram-negative bacterium Xanthomonas campestris pv. campestris. Xanthan is composed of polymerized pentasaccharide repeating units which are assembled by the sequential addition of glucose-1-phosphate, glucose, mannose, glucuronate, and mannose on a polyprenol phosphate carrier.
http://purl.obolibrary.org/obo/UPa_UPA01018	tylosin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of tylosin, a macrolide antibiotic produced by Streptomyces fradiae. The structure of tylosin is a 16-atom polyketide lactone (tylactone) with 3 sugars atached (D-mycaminose, &-deoxy-D-allose and L-mycaose).
http://purl.obolibrary.org/obo/UPa_UPA01019	mycinamicin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00473	polyketide biosynthesis		Biosynthesis of mycinamicin.
http://purl.obolibrary.org/obo/UPa_UPA01020	dafachronic acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00440	steroid hormone biosynthesis		Biosynthesis of dafachronic acids (DAs), which are steroid hormones and ligands for the nuclear receptor DAF-12.
http://purl.obolibrary.org/obo/UPa_UPA01021	neopentalenolactone biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of neopentalenolactone, a sesquiterpenoid antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA01022	branched-chain fatty acid metabolism	http://purl.obolibrary.org/obo/UPa_UPA00199	fatty acid metabolism		Metabolism of branched-chain fatty acid compounds.
http://purl.obolibrary.org/obo/UPa_UPA01023	15-methylhexadecasphinganine base metabolism	http://purl.obolibrary.org/obo/UPa_UPA00222	sphingolipid metabolism		Metabolism of 15-methylhexadecasphinganine base derivatives.
http://purl.obolibrary.org/obo/UPa_UPA01024	octadecasphinganine base metabolism	http://purl.obolibrary.org/obo/UPa_UPA00222	sphingolipid metabolism		Metabolism of octadecasphinganine base derivatives.
http://purl.obolibrary.org/obo/UPa_UPA01025	dodecasphinganine base metabolism	http://purl.obolibrary.org/obo/UPa_UPA00222	sphingolipid metabolism		Metabolism of dodecasphinganine base derivatives.
http://purl.obolibrary.org/obo/UPa_UPA01026	plastidic glycolysis	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		In plants glycolysis occurs in both cytosol and plastids, with reactions in the different compartments catalysed by separate isoenzymes. In chloroplasts, glycolysis is most active in conjunction with the breakdown of starch to form sucrose for export to non-photosynthetic tissues. There is some doubt about the occurrence of phosphoglycerate mutase in chloroplasts, and therefore the main products of the glycolytic reactions may be triose phosphates and 3-PGA. These could be exported through the Pi translocator in the chloroplast envelope to the cytosol, where sucrose synthesis takes place. In photosynthetic cells, the triose phosphate exported to the cytosol for sucrose synthesis could also enter the glycolytic pathway directly to provide mitochondrial substrates. [http://plantsinaction.science.uq.edu.au/edition1/?q=content/2-4-2-glycolytic-pathway].
http://purl.obolibrary.org/obo/UPa_UPA01027	spirilloxanthin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00386	carotenoid biosynthesis		Spirilloxanthin is a carotenoid synthesized by the photosynthetic non-sulfur purple bacterium Rhodospirillum rubrum. It was shown to be aggregated in large particles (apparent MW > 600 kDa) and was not associated with a specific protein. This acyclic, methylated carotenoid, as well as spheroidene, are accessory pigments, in the light-harvesting and reaction-center complexes in Rhodospirillum rubrum.
http://purl.obolibrary.org/obo/UPa_UPA01028	L-pyrrolysine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		L-pyrrolysine (abbreviated as Pyl or O) is a naturally occurring, genetically coded amino acid used by some methanogenic archaea and bacterium in enzymes that are part of their methane-producing metabolism. It forms part of an unusual genetic code in these organisms, and is considered the 22nd proteinogenic amino acid. It is necessary for all of the known pathways by which methane is formed from methylamines [PMID:21550296]. L-pyrrolysine is similar to lysine, but with an added pyrroline ring linked to the end of the lysine side chain. Pyrrolysine is synthesized in vivo by joining two molecules of L-lysine. One molecule of lysine is first converted to (3R)-3-Methyl-D-ornithine, which is then ligated to a second lysine. An amino group is eliminated, followed by cyclization and dehydration step to yield L-pyrrolysine.
http://purl.obolibrary.org/obo/UPa_UPA01029	rifamycin B biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of rifamycin B. The rifamycins are an important family of ansamycin antibiotics with anti-mycobacterial activity. rifamycin B is synthesized either naturally by the bacterium Amycolatopsis mediterranei (formerly Streptomyces mediterranei, Nocardia mediterranei) or artificially.
http://purl.obolibrary.org/obo/UPa_UPA01030	4-nitrophenol degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of 4-nitrophenol (also called p-nitrophenol or 4-hydroxynitrobenzene). 4-nitrophenol is a phenolic compound that has a nitro group at the opposite position of hydroxy group on the benzene ring.
http://purl.obolibrary.org/obo/UPa_UPA01031	carbazole degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of carbazole. Carbazole is an aromatic heterocyclic organic compound. It has a tricyclic structure, consisting of two six-membered benzene rings fused on either side of a five-membered nitrogen-containing ring.
http://purl.obolibrary.org/obo/UPa_UPA01032	1,8-cineol degradation	http://purl.obolibrary.org/obo/UPa_UPA00137	monoterpene degradation		Degradation of 1,8-cineol (eucalyptol). 1,8-cineole is a cyclic monoterpene containing an internal ether linkage. It is found in the oil from the leaves of Eucalyptus radiata var. Australiana and is used in the fragrance and flavor industries. Microorganisms metabolizing 1,8-cineole as sole carbon source must cleave both the ring and ether linkages.
http://purl.obolibrary.org/obo/UPa_UPA01033	4-chloronitrobenzene degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of 4-chloronitrobenzene. 4-Nitrochlorobenzene is a common intermediate in the production of a number of industrially useful compounds, including common antioxidants found in rubber.
http://purl.obolibrary.org/obo/UPa_UPA01034	aminocoumarin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		The aminocoumarin antibiotics comprise three classical compounds: novobiocin, clorobiocin and coumermycin A1. They are potent inhibitors of gyrase, competing with ATP for binding to the B subunit of DNA gyrase and thereby inhibiting the ATP-dependent DNA supercoiling catalysed by gyrase [PMID:10093705,PMID:12570764]. All three are produced by different Streptomyces strains [PMID:10770754], [PMID:11036020], [PMID:12480894] The novobiocin molecule comprises three structural moieties: the deoxy sugar noviose, a substituted 3-aminocoumarin moiety and a 3-prenylated 4-hydroxybenzoate moiety. Noviose is related to L-rhamnose, but shows an unusual 5,5-dimethyl structure and carries a carbamyl group at 3-OH and a methyl group at 4-OH. The aminocoumarin ring is substituted with hydroxy groups in positions 3 and 7. Novobiocin and coumermycin A1 carry a methyl group at position 8 of the aminocoumarin unit, while clorobiocin (also called chlorobiocin) is chlorinated in this position. In clorobiocin and coumermycin A1, the 3-OH of the deoxy sugar is connected with a 5-methylpyrrole-2-carboxyl moiety rather than with a carbamyl group. While clorobiocin contains the same prenylated 4-hydroxybenzoate moiety as novobiocin, the coumermycin A1 molecule contains a central 3-methylpyrrole-2,4-dicarboxylic acid moiety, which links two aminocoumarin-deoxy sugar assemblies in a nearly but not completely symmetrical fashion [PMID:16868863].
http://purl.obolibrary.org/obo/UPa_UPA01035	novobiocin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA01034	aminocoumarin biosynthesis		Biosynthesis of novobiocin. The novobiocin molecule comprises three structural moieties: the deoxy sugar noviose, a substituted 3-aminocoumarin moiety and a 3-prenylated 4-hydroxybenzoate moiety. Noviose is related to L-rhamnose, but shows an unusual 5,5-dimethyl structure and carries a carbamyl group at 3-OH and a methyl group at 4-OH. The aminocoumarin ring is substituted with hydroxy groups in positions 3 and 7. Novobiocin and coumermycin A1 carry a methyl group at position 8 of the aminocoumarin unit, while clorobiocin (also called chlorobiocin) is chlorinated in this position. In clorobiocin and coumermycin A1, the 3-OH of the deoxy sugar is connected with a 5-methylpyrrole-2-carboxyl moiety rather than with a carbamyl group. While clorobiocin contains the same prenylated 4-hydroxybenzoate moiety as novobiocin, the coumermycin A1 molecule contains a central 3-methylpyrrole-2,4-dicarboxylic acid moiety, which links two aminocoumarin-deoxy sugar assemblies in a nearly but not completely symmetrical fashion.
http://purl.obolibrary.org/obo/UPa_UPA01036	kanosamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00295	antibiotic biosynthesis		Biosynthesis of kanosamine, a naturally occurring antibiotic and component of oligosaccharide antibiotics such as kanamycin.
http://purl.obolibrary.org/obo/UPa_UPA01037	saturated fatty acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis		Biosynthesis of saturated fatty acids.
http://purl.obolibrary.org/obo/UPa_UPA01038	monounsaturated fatty acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis		Biosynthesis of mono unsaturated fatty acids.
http://purl.obolibrary.org/obo/UPa_UPA01039	branched-chain fatty acid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00094	fatty acid biosynthesis		Biosynthesis of branched fatty acids.
http://purl.obolibrary.org/obo/UPa_UPA01040	carminomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00127	anthracycline biosynthesis		Biosynthesis of carminomycin, a potent antitumor anthracycline antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA01041	doxorubicin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00127	anthracycline biosynthesis		Biosynthesis of doxorubicin, a potent antitumor anthracycline antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA01042	rhodomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00127	anthracycline biosynthesis		Biosynthesis of rhodomycin, a potent antitumor anthracycline antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA01043	aclacinomycin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00127	anthracycline biosynthesis		Biosynthesis of aclacinomycin, a potent antitumor anthracycline antibiotic.
http://purl.obolibrary.org/obo/UPa_UPA01044	xyloglucan metabolism	http://purl.obolibrary.org/obo/UPa_UPA00001	biological process		Metabolism of xyloglucan, a hemicellulose that occurs in the primary cell wall of all vascular plants.
http://purl.obolibrary.org/obo/UPa_UPA01045	xyloglucan degradation	http://purl.obolibrary.org/obo/UPa_UPA01044	xyloglucan metabolism		Degradation of xyloglucan, a hemicellulose that occurs in the primary cell wall of all vascular plants.
http://purl.obolibrary.org/obo/UPa_UPA01046	D-galacturonate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Metabolism of D-galacturonate, a component of pectin.
http://purl.obolibrary.org/obo/UPa_UPA01047	D-galacturonate degradation	http://purl.obolibrary.org/obo/UPa_UPA01046	D-galacturonate metabolism		Degradation of D-galacturonate, a component of pectin. For the microbial catabolism, three different pathways have been described, (i) a reductive pathway, (ii) an isomerase pathway, (iii) an oxidative pathway.
http://purl.obolibrary.org/obo/UPa_UPA01048	D-galacturonate degradation via prokaryotic reductive pathway	http://purl.obolibrary.org/obo/UPa_UPA01047	D-galacturonate degradation		The prokaryotic degradation of D-galacturonate via the reductive pathway.
http://purl.obolibrary.org/obo/UPa_UPA01049	D-galacturonate degradation via prokaryotic isomerase pathway	http://purl.obolibrary.org/obo/UPa_UPA01047	D-galacturonate degradation		The prokaryotic degradation of D-galacturonate via the isomerase pathway.
http://purl.obolibrary.org/obo/UPa_UPA01050	D-galacturonate degradation via prokaryotic oxidative pathway	http://purl.obolibrary.org/obo/UPa_UPA01047	D-galacturonate degradation		The prokaryotic degradation of D-galacturonate via the oxidative pathway.
http://purl.obolibrary.org/obo/UPa_UPA01051	D-galacturonate degradation via eukaryotic pathway	http://purl.obolibrary.org/obo/UPa_UPA01047	D-galacturonate degradation		The Degradation of D-galacturonate in eukaryotes. Yeast and mould can grow with d-galacturonic acid as a sole carbon source; however, a pathway different from the prokaryotic pathways is used.
http://purl.obolibrary.org/obo/UPa_UPA01052	glycosphingolipid biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of glycosphingolipids, a subtype of glycolipids containing the amino alcohol sphingosine. Glycosphingolipids (GSLs) are found in the cell membranes of organisms from bacteria to man, and are the major glycans of the vertebrate brain, where more than 80% of glycoconjugates are in the form of glycolipids.
http://purl.obolibrary.org/obo/UPa_UPA01053	phylloquinone metabolism	http://purl.obolibrary.org/obo/UPa_UPA01055	quinol/quinone metabolism		Metabolism of phylloquinone (also called vitamine K1 or phytonadione), a lipid-soluble molecule that belongs to the naphto-quinone family.
http://purl.obolibrary.org/obo/UPa_UPA01054	phylloquinone degradation	http://purl.obolibrary.org/obo/UPa_UPA01056	quinol/quinone degradation		Degradation of phylloquinone (also called vitamine K1 or phytonadione), a lipid-soluble molecule that belongs to the naphto-quinone family.
http://purl.obolibrary.org/obo/UPa_UPA01055	quinol/quinone metabolism	http://purl.obolibrary.org/obo/UPa_UPA00398	cofactor metabolism		Metabolism of quinol/quinone cofactors, such as menaquinone (vitamin K2), ubiquinone (coenzyme Q) or phylloquinone (vitamin K1).
http://purl.obolibrary.org/obo/UPa_UPA01056	quinol/quinone degradation	http://purl.obolibrary.org/obo/UPa_UPA01055	quinol/quinone metabolism		Degradation of quinone cofactors, such as menaquinone (vitamin K2), ubiquinone (coenzyme Q) or phylloquinone (vitamin K1).
http://purl.obolibrary.org/obo/UPa_UPA01057	1,4-dihydroxy-2-naphthoate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00829	quinol/quinone biosynthesis		Biosynthesis of 1,4-dihydroxy-2-naphthoate, the naphtalenic intermediate in the biosynthesis of several quinol/quinone cofactors such as menaquinone (vitamin K2) or phylloquinone (vitamin K1).
http://purl.obolibrary.org/obo/UPa_UPA01058	cholesterol degradation	http://purl.obolibrary.org/obo/UPa_UPA00296	cholesterol metabolism		The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids.
http://purl.obolibrary.org/obo/BFO_0000004	independent continuant	http://purl.obolibrary.org/obo/BFO_0000002	continuant		A continuant that is a bearer of quality and realizable entity entities, in which other entities inhere and which itself cannot inhere in anything.
http://purl.obolibrary.org/obo/BFO_0000015	process	http://purl.obolibrary.org/obo/BFO_0000003	occurrent		An occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t.
http://purl.obolibrary.org/obo/BFO_0000040	material entity	http://purl.obolibrary.org/obo/BFO_0000004	independent continuant		An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time.
http://purl.obolibrary.org/obo/UPa_UPC00087	sulfur	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00140	N-acetyl-D-glucosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00162	fatty acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00165	diacylglycerol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00182	glycogen	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00187	cholesterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00208	maltose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00219	arachidonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00237	CO	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00246	butanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00247	L-sorbose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00248	lipoamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00333	D-galacturonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00348	undecaprenyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00369	starch	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00390	ubiquinol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00395	penicillin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00399	ubiquinone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00413	streptomycin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00459	dTTP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00461	chitin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00466	acetoin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00487	carnitine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00524	cytochrome c	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00579	dihydrolipoamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00597	3-phosphoglycerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00661	glyceraldehyde 3-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00707	xylan	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00768	histidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00770	L-idonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00806	tryptophan	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00828	menaquinone-2	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00829	naphthalene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00870	4-nitrophenol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00875	cephalosporin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00889	peptidoglycan	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00916	cephalosporin C	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00954	ndole-3-acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00976	GDP-D-mannuronate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01177	1D-myo-inositol 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01328	OH(-)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01353	carbonic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01371	alkane	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01401	alanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01416	cocaine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01432	lactate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01449	queuine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01450	ketone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01457	tylosin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01579	flavonoid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01582	galactose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01667	bacitracin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01682	nopaline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01742	palatinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01748	pyocyanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01762	xanthosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01768	alginate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01848	rifamycin B	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01977	tRNA-guanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01978	tRNA-queuine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02059	phylloquinone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02112	2-acylglycerol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02315	protein dithiol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02385	arginine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02477	tocopherol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02582	protein disulfide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02713	N-acetylmuramate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02905	tRNA-queuosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03004	N-hydroxy-L-tyrosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03319	dTDP-L-rhamnose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03340	(S)-2,3-dihydrodipicolinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03428	presqualene diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03438	beta-lactam	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03664	(2,4-dichlorophenoxy)acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04021	phosphatidylinositol phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04146	all-trans-octaprenyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04256	N-acetyl-D-glucosamine 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05042	phosphinothricin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05080	novobiocin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05325	purine nucleotide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05381	3-carboxy-1-hydroxypropylthiamine diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05431	neurosporene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05554	aerobactin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05570	ergothioneine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05618	3-chlorocatechol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05818	2-demethylmenaquinone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05821	enterochelin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06008	(R)-2-oxo-3-methylpentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06078	limonene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06317	vanillyl-alcohol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06457	bialaphos	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06542	ajmaline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06566	cephamycin C	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06609	trans-1,3-dichloropropene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06610	cis-1,3-dichloropropene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06611	trans-3-chloro-2-propene-1-ol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06612	cis-3-Chloro-2-propene-1-ol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06613	3-chloroallyl aldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06614	trans-3-chloroacrylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06615	cis-3-chloroacrylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06669	carbapenem	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06689	vancomycin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06690	candicidin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06691	actinorhodin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06693	monensin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06769	vibriobactin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06799	granaticin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06801	tetracenomycin C	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06812	lincomycin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06891	D-2,3-dioxo-4-deoxy-epi-inositol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07100	(2,4,5-trichlorophenoxy)acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08060	carbazole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08215	thyroid hormone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08580	astaxanthin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08606	neoxanthin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08737	melamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC09844	1,8-cineole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC10172	stachydrine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11020	2-(2,4-dichlorophenoxy)propanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11088	1,2-dibromoethane	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11218	gramicidin S	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11541	cobalt-precorrin 5	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12041	tyrocidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12043	surfactin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12212	kanosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12216	mycobactin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12219	bacillibactin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12986	N-acetyl-L-2-aminoadipate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12987	N-acetyl-L-2-aminoadipate 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12988	N-acetyl-L-2-aminoadipate semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12989	N-acetyl-L-lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC13856	2-arachidonoylglycerol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC14456	4-chloronitrobenzene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15503	N,N-dihydroxy-L-tyrosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15549	anthocyanin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15900	spheroidene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15996	7-cyano-7-deazaguanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16269	epi-isozizaene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16286	geosmin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16348	cis-3-chloroallyl aldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16386	(R)-nicotine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16440	lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16463	3',5'-cyclic di-GMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16589	2-oxosuberate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16665	12-methyltetradecanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC17708	fortimicin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19882	D-glycero-D-manno-heptose 7-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC20151	10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00029	trisporate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00030	fructose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00031	methylnaphthalene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00033	polyhydroxyalkanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00034	terpenoid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00035	nucleotide-sugar	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00036	amino-sugar	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00037	bile acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00038	sphingolipid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00039	xylene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00040	C21-steroid hormone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00041	glycerolipid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00042	1,6-anhydro-N-acetylmuramate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00043	aldonic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00044	aldaric acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00045	tartrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00046	mycolic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00047	poly-(R)-3-hydroxybutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00048	colanic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00049	lactose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00050	2-deoxy-D-ribose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00051	4-amino-4-deoxy-beta-L-arabinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00052	4-amino-4-deoxy-beta-L-arabinose-lipid A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00053	lipid A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00054	tetrahydrofolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00055	ectoine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00056	trehalose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/GO_0003674	molecular_function	http://purl.obolibrary.org/obo/BFO_0000015	process		
http://purl.obolibrary.org/obo/GO_0008150	biological_process	http://purl.obolibrary.org/obo/BFO_0000015	process		
http://purl.obolibrary.org/obo/UPa_UCR00005	H(2)O + urea-1-carboxylate = 2 CO(2) + 2 NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00010	H(2)O + alpha,alpha-trehalose = 2 D-glucose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00013	2 glyoxylate = 2-hydroxy-3-oxopropanoate + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00014	pyruvate + thiamine diphosphate = 2-hydroxyethyl-ThPP + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00021	2 L-glutamate + 2 oxidized ferredoxin = 2-oxoglutarate + 2 H(+) + L-glutamine + 2 reduced ferredoxin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00036	2 5-aminolevulinate = 2 H(2)O + porphobilinogen	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00066	2 6,7-dimethyl-8-(1-D-ribityl)lumazine = 5-amino-6-(D-ribitylamino)uracil + riboflavin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00084	H(2)O + 4 porphobilinogen = 4 NH(3) + hydroxymethylbilane	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00093	2 L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + L-glutamine + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00114	2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00127	AMP + ATP = 2 ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00130	3'-dephospho-CoA + ATP = ADP + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00131	H(2)O + urea = CO(2) + 2 NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00137	ATP + nicotinamide D-ribonucleotide = NAD(+) + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00150	ATP + CO(2) + NH(3) = ADP + carbamoyl phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00156	ATP + UDP = ADP + UTP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00158	ATP + UMP = ADP + UDP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00161	ATP + FMN = FAD + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00173	H(2)O + pyridoxal 5'-phosphate = phosphate + pyridoxal	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00174	ATP + pyridoxal = ADP + pyridoxal 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00177	S-adenosyl-L-methionine + diphosphate + phosphate = ATP + H(2)O + L-methionine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00178	H(+) + S-adenosyl-L-methionine = CO(2) + S-adenosylmethioninamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00179	S-adenosyl-L-methionine = 1-aminocyclopropanecarboxylate + S-methyl-5'-thioadenosine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00181	AMP + H(2)O = IMP + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00185	ATP + adenosine = ADP + AMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00189	ATP + NH(3) + deamido-NAD(+) = AMP + NAD(+) + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00190	AMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + adenine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00191	3',5'-cyclic AMP + H(2)O = AMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00192	H(2)O + S-adenosyl-L-homocysteine = L-homocysteine + adenosine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00200	ATP + pyruvate = ADP + phosphoenolpyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00212	acetyl-CoA + formate = CoA + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00226	(S)-2-acetolactate + CO(2) = 2 pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00228	CoA + NAD(+) + acetaldehyde = H(+) + NADH + acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00230	acetyl-CoA + phosphate = CoA + acetyl phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00233	malonyl-CoA = CO(2) + acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00238	2 acetyl-CoA = CoA + acetoacetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00239	ATP + L-glutamate = ADP + L-glutamyl 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00243	H(2)O + L-glutamate + NAD(+) = 2-oxoglutarate + H(+) + NADH + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00253	ATP + L-glutamate + NH(3) = ADP + L-glutamine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00256	H(2)O + L-glutamine = L-glutamate + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00257	ATP + H(2)O + L-glutamine + deamido-NAD(+) = AMP + L-glutamate + NAD(+) + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00258	2-oxoglutarate + L-alanine = L-glutamate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00259	L-glutamate + acetyl-CoA = CoA + N-acetyl-L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00262	(2S,3S)-3-methyl-L-aspartate = L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00264	2,5-dioxopentanoate + H(2)O + NADP(+) = 2-oxoglutarate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00267	NADP(+) + isocitrate = 2-oxoglutarate + CO(2) + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00271	2-oxoglutarate + H(2)O + acetyl-CoA = (R)-homocitrate + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00272	2-oxoglutarate = CO(2) + succinate semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00277	H(2)O + O(2) + pyridoxamine 5'-phosphate = H(2)O(2) + NH(3) + pyridoxal 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00278	O(2) + pyridoxine 5'-phosphate = H(2)O(2) + pyridoxal 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00286	H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 2 H(+) + 2 NADH + UDP-alpha-D-glucuronate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00294	2 H(+) + 2 ferrocytochrome c + 2 nitric oxide = H(2)O + 2 ferricytochrome c + nitrous oxide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00299	ATP + D-glucose = ADP + D-glucose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00310	Fe2+ + protoporphyrin-IX = 2 H(+) + protoheme	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00315	ATP + acetate = ADP + acetyl phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00325	L-citramalate = acetate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00336	H(2)O + ppGpp = GDP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00342	(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00351	CoA + citrate = H(2)O + acetyl-CoA + oxaloacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00355	2-oxoglutarate + L-aspartate = L-glutamate + oxaloacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00361	(S)-malate + Quinone = Hydroquinone + oxaloacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00367	S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00369	L-alanine + glyoxylate = glycine + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00371	acetyl-CoA + glycine = CoA + L-2-amino-3-oxobutanoic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00372	2-oxoglutarate + glycine = L-glutamate + glyoxylate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00396	H(2)O + L-alanine + NAD(+) = H(+) + NADH + NH(3) + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00401	L-alanine = D-alanine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00405	ATP + CoA + succinate = ADP + phosphate + succinyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00410	acetoacetate + succinyl-CoA = acetoacetyl-CoA + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00411	H(2)O + N(2)-succinyl-L-glutamic acid = L-glutamate + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00412	acceptor + succinate = fumarate + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00416	N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = UDP-N-acetyl-alpha-D-glucosamine + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00425	GTP + 3 H(2)O = 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + diphosphate + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00428	GTP + H(2)O = formamidopyrimidine nucleoside triphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00429	ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00451	DL-2,6-diaminopimelate = CO(2) + L-lysine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00469	(S)-ureidoglycolate + H(2)O = CO(2) + 2 NH(3) + glyoxylate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00472	(S)-malate + CoA = H(2)O + acetyl-CoA + glyoxylate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00475	O(2) + glycolate = H(2)O(2) + glyoxylate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00476	acceptor + glycolate = glyoxylate + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00479	isocitrate = glyoxylate + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00480	ATP + L-aspartate = 4-phospho-L-aspartate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00481	L-aspartate + O(2) = H(2)O(2) + iminoaspartate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00483	ATP + L-aspartate + NH(3) = AMP + L-asparagine + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00489	L-aspartate = CO(2) + beta-alanine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00497	ATP + L-gamma-glutamyl-L-cysteine + glycine = ADP + glutathione + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00509	5'-adenylyl sulfate + ATP = 3'-phospho-5'-adenylyl sulfate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00512	ATP + CMP = ADP + CDP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00513	ATP + cytidine = ADP + CMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00525	H(2)O + N-formyl-L-glutamate = L-glutamate + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00527	H(2)O + S-formylglutathione = formate + glutathione	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00529	ATP + sulfate = 5'-adenylyl sulfate + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00549	ATP + riboflavin = ADP + FMN	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00551	H(2)O + L-arginine = L-ornithine + urea	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00552	H(2)O + L-arginine = L-citrulline + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00565	L-arginine + glycine = L-ornithine + guanidinoacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00566	L-arginine = CO(2) + agmatine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00570	ATP + CDP = ADP + CTP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00571	ATP + NH(3) + UTP = ADP + CTP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00575	2 ATP + H(2)O + L-glutamine + bicarbonate = 2 ADP + L-glutamate + carbamoyl phosphate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00578	ATP + H(2)O + L-aspartate + L-glutamine = AMP + L-asparagine + L-glutamate + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00582	H(2)O + O-phospho-L-serine = L-serine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00585	L-serine + pyruvate = 3-hydroxypyruvate + L-alanine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00586	L-serine + acetyl-CoA = CoA + O-acetyl-L-serine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00605	NAD(+) + methanol = H(+) + NADH + formaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00606	H(2)O + amicyanin + methylamine = 2 H(+) + NH(3) + formaldehyde + reduced amicyanin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00611	H(2)O + electron-transferring flavoprotein + sarcosine = formaldehyde + glycine + reduced electron-transferring flavoprotein	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00617	ATP + thiamine phosphate = ADP + thiamine diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00619	ATP + thiamine = AMP + thiamine diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00640	L-Galactono-1,4-lactone + 2 ferricytochrome c = 2 H(+) + L-ascorbate + 2 ferrocytochrome c	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00647	L-ascorbate = L-xylo-hexulonolactone	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00658	2-phospho-D-glycerate = H(2)O + phosphoenolpyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00667	2-oxoglutarate + L-ornithine = L-glutamate + L-glutamate 5-semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00669	H(2)O + N(2)-acetyl-L-ornithine = L-ornithine + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00670	L-ornithine = CO(2) + putrescine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00671	L-ornithine = L-proline + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00673	H(2)O + L-tryptophan = NH(3) + indole + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00674	L-serine + indole = H(2)O + L-tryptophan	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00678	L-tryptophan + O(2) = N-formyl-N-kynurenine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00688	H(2)O + L-phenylalanine + NAD(+) = H(+) + NADH + NH(3) + phenylpyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00691	L-arogenate = CO(2) + H(2)O + L-phenylalanine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00694	2-oxoglutarate + L-phenylalanine = L-glutamate + phenylpyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00697	L-phenylalanine = NH(3) + trans-cinnamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00699	L-phenylalanine = 2-phenylethylamine + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00703	(S)-lactate + NAD(+) = H(+) + NADH + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00705	3-oxopropanoate + CoA + NAD(+) = CO(2) + H(+) + NADH + acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00706	3-oxopropanoate + CoA + NADP(+) = CO(2) + H(+) + NADPH + acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00707	(S)-1-pyrroline-5-carboxylic acid + 2 H(2)O + NAD(+) = H(+) + L-glutamate + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00709	NAD(+) + isocitrate = 2-oxoglutarate + CO(2) + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00710	H(2)O + NAD(+) + acetaldehyde = H(+) + NADH + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00713	H(2)O + NAD(+) + succinate semialdehyde = H(+) + NADH + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00714	H(2)O + NADP(+) + succinate semialdehyde = H(+) + NADPH + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00715	H(2)O + NAD(+) + saccharopine = 2-oxoglutarate + H(+) + L-lysine + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00716	H(2)O + NADP(+) + saccharopine = 2-oxoglutarate + H(+) + L-lysine + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00731	L-tyrosine + O(2) = H(2)O + L-dopa	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00732	L-arogenate + NAD(+) = CO(2) + H(+) + L-tyrosine + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00733	L-arogenate + NADP(+) = CO(2) + H(+) + L-tyrosine + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00734	2-oxoglutarate + L-tyrosine = (4-hydroxyphenyl)pyruvate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00742	ATP + acetyl-CoA + bicarbonate = ADP + malonyl-CoA + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00750	acetaldehyde + pyruvate = 4-hydroxy-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00751	L-threonine = acetaldehyde + glycine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00754	NAD(+) + ethanol = H(+) + NADH + acetaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00756	ATP + D-fructose 6-phosphate = ADP + D-fructose 1,6-bisphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00765	H(2)O + alpha-D-glucosamine 6-phosphate = D-fructose 6-phosphate + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00766	D-fructose 6-phosphate + UDP-alpha-D-glucose = UDP + sucrose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00768	D-fructose 6-phosphate + L-glutamine = L-glutamate + alpha-D-glucosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00771	D-glucose 6-phosphate = D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00772	D-mannose 6-phosphate = D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00774	ATP + bicarbonate + urea = ADP + phosphate + urea-1-carboxylate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00783	H(2)O + ferricytochrome c + nitric oxide = H(+) + ferrocytochrome c + nitrite	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00798	H(2)O + acceptor + nitrite = nitrate + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00805	H(2)O + sucrose 6-phosphate = phosphate + sucrose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00812	NAD(+) + cis-1,2-dihydrobenzene-1,2-diol = H(+) + NADH + catechol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00813	(1R,6S)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid + NAD(+) = CO(2) + H(+) + NADH + catechol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00817	O(2) + catechol = cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00823	H(+) + NADH + O(2) + anthranilate = CO(2) + NAD(+) + NH(3) + catechol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00829	acetyl-CoA + succinyl-CoA = 3-oxoadipyl-CoA + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00830	glycine + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00832	L-arginine + succinyl-CoA = CoA + N(2)-succinyl-L-arginine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00833	(R)-methylmalonyl-CoA = succinyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00835	D-glucose 6-phosphate + NADP(+) = D-glucono-1,5-lactone 6-phosphate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00847	ATP + glycerol = ADP + sn-glycerol 3-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00849	Quinone + sn-glycerol 3-phosphate = Hydroquinone + glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00851	acyl-CoA + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00858	3 H(2)O + 3 NADP(+) + hydrogen sulfide = 3 H(+) + 3 NADPH + sulfite	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00859	3 H(2)O + hydrogen sulfide + 6 oxidized ferredoxin = 6 H(+) + 6 reduced ferredoxin + sulfite	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00874	D-fructose + D-glucose = D-glucono-1,5-lactone + D-sorbitol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00883	GDP + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00885	GTP + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00888	GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-D-mannose + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00893	L-cysteine + O(2) = 3-sulfino-L-alanine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00894	ATP + L-cysteine + L-glutamate = ADP + L-gamma-glutamyl-L-cysteine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00897	O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00901	L-cysteine + sulfite = L-cysteate + hydrogen sulfide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00921	phosphate + propanoyl-CoA = CoA + propanoyl phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00939	5,6,7,8-tetrahydrofolate + NADP(+) = 7,8-dihydrofolate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00944	10-formyl-5,6,7,8-tetrahydrofolate + H(2)O = 5,6,7,8-tetrahydrofolate + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00945	5,10-methylene-THF + H(2)O + glycine = 5,6,7,8-tetrahydrofolate + L-serine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00946	5-methyl-THF + L-homocysteine = 5,6,7,8-tetrahydrofolate + L-methionine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00956	CTP + alpha-D-glucose 1-phosphate = CDP-glucose + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00964	ATP + uridine = ADP + UMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00965	orotidine 5'-phosphate = CO(2) + UMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00966	UMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + uracil	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00974	H(2)O + cytosine = NH(3) + uracil	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00976	H(2)O + acceptor + uracil = barbiturate + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00985	NH(3) + chorismate = H(2)O + anthranilate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00987	H(2)O + L-kynurenine = L-alanine + anthranilate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00994	2-oxobutanoate + CO(2) + H(+) + NADH = D-erythro-3-methylmalic acid + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR00996	L-threonine = 2-oxobutanoate + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01001	H(2)O + L-cystathionine = 2-oxobutanoate + L-cysteine + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01011	ATP + glycerone = ADP + glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01015	D-glyceraldehyde 3-phosphate = glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01021	ATP + choline = ADP + phosphocholine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01022	O(2) + choline = H(2)O(2) + betaine aldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01025	acceptor + choline = betaine aldehyde + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01028	H(2)O + choline sulfate = choline + sulfate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01034	NAD(+) + glycerol = H(+) + NADH + glycerone	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01047	glycerol = 3-hydroxypropanal + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01049	ATP + D-ribose 5-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + AMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01051	ATP + D-ribose = ADP + D-ribose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01056	D-ribose 5-phosphate = D-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01057	alpha-D-ribose 1-phosphate = D-ribose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01061	D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = 3-phospho-D-glyceroyl phosphate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01064	6-phospho-2-dehydro-3-deoxy-D-galactonic acid = D-glyceraldehyde 3-phosphate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01066	2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01068	D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01069	D-tagatose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01071	1-(5-phospho-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01072	5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + H(2)O + L-glutamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01073	N-(5-phospho-beta-D-ribosyl)anthranilic acid + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01078	2 H(+) + 2 S-adenosyl-L-methionine + dethiobiotin + 2 e- + sulfur donor = 2 5'-deoxyadenosine + 2 L-methionine + biotin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01080	H(2)O + uridine = D-ribose + uracil	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01082	(S)-malate = H(2)O + fumarate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01083	N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01086	(N(omega)-L-arginino)succinate = L-arginine + fumarate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01088	H(2)O + L-leucine + NAD(+) = 4-methyl-2-oxopentanoate + H(+) + NADH + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01090	2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01121	(R)-5-diphosphomevalonate + ATP = ADP + CO(2) + isopentenyl diphosphate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01123	isopentenyl diphosphate = dimethylallyl diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01127	H(2)O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01130	H(2)O + IMP + NAD(+) = H(+) + NADH + XMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01131	ATP + inosine = ADP + IMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01132	IMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01135	GTP + IMP + L-aspartate = GDP + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01151	H(2)O + O(2) + putrescine = 4-aminobutanal + H(2)O(2) + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01152	H(2)O + N-carbamoylputrescine = CO(2) + NH(3) + putrescine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01154	acetyl-CoA + putrescine = CoA + N-acetylputrescine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01155	2-oxoglutarate + putrescine = 4-aminobutanal + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01157	H(2)O + agmatine = putrescine + urea	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01158	H(2)O + L-histidinol + 2 NAD(+) = 2 H(+) + L-histidine + 2 NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01167	L-histidine = CO(2) + histamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01168	L-histidine = NH(3) + trans-urocanate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01183	NAD(+) + myo-inositol = H(+) + NADH + scyllo-inosose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01184	O(2) + myo-inositol = D-glucuronate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01187	1D-myo-inositol 3-phosphate + H(2)O = myo-inositol + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01197	CO(2) + 2 H(+) + 2 reduced ferredoxin + succinyl-CoA = 2-oxoglutarate + CoA + 2 oxidized ferredoxin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01213	(2S)-2-isopropylmalate + CoA = 3-methyl-2-oxobutanoate + H(2)O + acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01214	2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01226	3-methyl-2-oxobutanoate + 5,10-methylene-THF + H(2)O = 2-dehydropantoate + 5,6,7,8-tetrahydrofolate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01229	GMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + guanine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01230	ATP + NH(3) + XMP = AMP + GMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01231	ATP + H(2)O + L-glutamine + XMP = AMP + GMP + L-glutamate + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01234	3',5'-cyclic GMP + H(2)O = GMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01248	L-proline + NAD(+) = (S)-1-pyrroline-5-carboxylic acid + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01253	L-proline + Quinone = (S)-1-pyrroline-5-carboxylic acid + Hydroquinone	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01268	H(2)O + nicotinamide = NH(3) + nicotinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01271	diphosphate + nicotinamide D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + nicotinamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01286	H(2)O + L-cystathionine = L-homocysteine + NH(3) + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01287	O-acetyl-L-homoserine + hydrogen sulfide = L-homocysteine + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01288	O-succinyl-L-homoserine + hydrogen sulfide = L-homocysteine + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01290	L-homocysteine + L-serine = H(2)O + L-cystathionine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01295	H(+) + NADPH + O(2) + benzoate = 4-hydroxybenzoate + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01298	4-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01301	4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01321	1,2-diacyl-sn-glycerol + CDP-choline = CMP + phosphatidylcholine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01325	citrate = H(2)O + cis-aconitate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01334	2-phosphoglycolate + H(2)O = glycolate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01353	ATP + propanoate = ADP + propanoyl phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01355	(2R,3S)-2,3-dimethylmalate = propanoate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01360	(S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01364	acetoacetate + fumarate = 4-fumarylacetoacetate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01373	prephenate = CO(2) + H(2)O + phenylpyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01384	UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01388	D-glycerate + NAD(+) = 3-hydroxypyruvate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01392	D-glycerate + NADP(+) = 3-hydroxypyruvate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01397	L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01398	L-ornithine + carbamoyl phosphate = L-citrulline + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01399	carbamoyl phosphate + putrescine = N-carbamoylputrescine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01401	H(2)O + S-methyl-5'-thioadenosine = 5-methylthio-alpha-D-ribose + adenine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01402	S-methyl-5'-thioadenosine + phosphate = S-methyl-5-thio-alpha-D-ribose 1-phosphate + adenine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01416	H(2)O + agmatine = N-carbamoylputrescine + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01419	H(2)O + NAD(+) + benzaldehyde = H(+) + NADH + benzoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01420	H(2)O + NADP(+) + benzaldehyde = H(+) + NADPH + benzoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01465	L-threonine + NAD(+) = H(+) + L-2-amino-3-oxobutanoic acid + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01466	H(2)O + O-phospho-L-homoserine = L-threonine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01468	ATP + ethanolamine = ADP + phosphoethanolamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01473	UDP-L-arabinose = UDP-alpha-D-xylose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01481	L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01512	3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01513	3-phospho-D-glycerate + NAD(+) = 3-phosphohydroxypyruvate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01514	ATP + D-glycerate = 3-phospho-D-glycerate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01518	2-phospho-D-glycerate = 3-phospho-D-glycerate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01519	D-glucono-1,5-lactone + H(2)O = D-gluconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01528	6-phospho-D-gluconate + NADP(+) = CO(2) + D-ribulose 5-phosphate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01529	D-ribulose 5-phosphate = D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01530	D-arabinose 5-phosphate = D-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01541	2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconic acid + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01542	2-dehydro-3-deoxy-D-gluconate + NAD(+) = 3-deoxy-D-glycero-hexo-2,5-diulosonate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01563	H(2)O + N-carbamoylsarcosine = CO(2) + NH(3) + sarcosine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01565	H(2)O + N,N-dimethylglycine + electron-transferring flavoprotein = formaldehyde + reduced electron-transferring flavoprotein + sarcosine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01567	ATP + thymidine = ADP + dTMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01570	phosphate + thymidine = 2-deoxy-alpha-D-ribose 1-phosphate + thymine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01574	D-arabinose + NAD(+) = D-arabinono-1,4-lactone + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01575	D-arabinose + NADP(+) = D-arabinono-1,4-lactone + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01614	4-coumaroyl-CoA + 3 malonyl-CoA = 3,4',5-trihydroxystilbene + 4 CO(2) + 4 CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01616	ATP + CoA + trans-4-coumarate = 4-coumaroyl-CoA + AMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01620	L-lysine + acetyl phosphate = N(6)-acetyl-L-lysine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01627	3-dehydroshikimate = 3,4-dihydroxybenzoate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01629	3,4-dihydroxybenzoate + H(+) + NADH + O(2) = CO(2) + H(2)O + NAD(+) + benzene-1,2,4-triol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01630	3,4-dihydroxybenzoate + H(+) + NADPH + O(2) = CO(2) + H(2)O + NADP(+) + benzene-1,2,4-triol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01631	3,4-dihydroxybenzoate + O(2) = 3-carboxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01635	4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01639	ATP + D-xylulose = ADP + D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01641	D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01647	pyruvate + succinate semialdehyde = 2,4-dihydroxyhept-2-enedioic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01648	2-oxoglutarate + 4-aminobutanoate = L-glutamate + succinate semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01651	4-methyl-2-oxopentanoate + CoA + NAD(+) = 3-isovaleryl-CoA + CO(2) + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01652	4-methyl-2-oxopentanoate + CO(2) = 3-carboxy-4-methyl-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01658	dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01676	H(2)O + guanine = NH(3) + xanthine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01681	H(2)O + NAD(+) + hypotaurine = H(+) + NADH + taurine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01682	L-cysteate = CO(2) + taurine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01707	NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01708	NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01711	O(2) + pyridoxine = H(2)O(2) + pyridoxal	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01712	pyridoxamine + pyruvate = L-alanine + pyridoxal	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01714	5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01715	chorismate = prephenate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01717	chorismate = isochorismate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01720	H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01724	ADP + diphosphate + nicotinate D-ribonucleotide + phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(+) + H(2)O + nicotinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01728	NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01730	NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01731	L-arogenate + oxaloacetate = L-aspartate + prephenate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01736	(R)-S-lactoylglutathione + H(2)O = (R)-lactate + glutathione	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01745	D-glycerate + NAD(+) = 2-hydroxy-3-oxopropanoate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01747	D-glycerate + NADP(+) = 2-hydroxy-3-oxopropanoate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01749	CO(2) + D-glycerate + NAD(+) = 2-hydroxy-3-oxosuccinate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01750	CO(2) + D-glycerate + NADP(+) = 2-hydroxy-3-oxosuccinate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01751	L-tartrate = CO(2) + D-glycerate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01757	L-arabinose + NAD(+) = H(+) + L-arabinono-1,4-lactone + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01758	L-arabinitol + NAD(+) = H(+) + L-arabinose + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01759	L-arabinitol + NADP(+) = H(+) + L-arabinose + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01761	L-arabinose = L-ribulose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01764	phenylglyoxylate = CO(2) + benzaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01768	H(2)O + NAD(+) + hypoxanthine = H(+) + NADH + xanthine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01771	ATP + L-homoserine = ADP + O-phospho-L-homoserine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01773	L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01775	L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01776	L-homoserine + acetyl-CoA = CoA + O-acetyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01777	L-homoserine + succinyl-CoA = CoA + O-succinyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01784	2-dehydro-3-deoxy-L-arabinonate = glycolaldehyde + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01793	H(+) + NADH + dihydrobiopterin = NAD(+) + tetrahydrobiopterin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01794	H(+) + NADPH + dihydrobiopterin = NADP(+) + tetrahydrobiopterin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01797	CDP-diacylglycerol + H(2)O = CMP + phosphatidate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01799	CTP + phosphatidate = CDP-diacylglycerol + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01800	CDP-diacylglycerol + L-serine = CMP + phosphatidylserine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01801	CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + phosphatidylglycerophosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01811	N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01812	2 NADP(+) + tetrahydrobiopterin = 2 H(+) + 2 NADPH + biopterin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01813	NADP(+) + tetrahydrobiopterin = 6-lactoyl-5,6,7,8-tetrahydropterin + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01818	D-mannose 6-phosphate = alpha-D-mannose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01825	D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01826	D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01827	D-glyceraldehyde 3-phosphate + sedoheptulose 7-phosphate = D-erythrose 4-phosphate + beta-D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01830	D-glyceraldehyde 3-phosphate + beta-D-fructose 6-phosphate = D-erythrose 4-phosphate + D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01859	ATP + bicarbonate + propanoyl-CoA = (S)-methylmalonyl-CoA + ADP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01867	(S)-dihydroorotate + fumarate = orotate + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01868	(S)-dihydroorotate + Quinone = Hydroquinone + orotate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01869	(S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01870	diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01872	D-quinate + NAD(+) = 3-dehydroquinate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01873	D-quinate + pyrroloquinoline quinone = 3-dehydroquinate + pyrroloquinoline quinol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01876	phosphate + uridine = alpha-D-ribose 1-phosphate + uracil	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01878	H(2)O + cytidine = NH(3) + uridine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01883	S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01890	CTP + phosphocholine = CDP-choline + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01896	NAD(+) + xylitol = D-xylulose + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01900	isocitrate = H(2)O + cis-aconitate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01903	L-arabinitol + NAD(+) = H(+) + L-xylulose + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01904	NADP(+) + xylitol = H(+) + L-xylulose + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01908	oxalyl-CoA = CO(2) + formyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01909	ATP + pyridoxine = ADP + pyridoxine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01911	phosphate + pyridoxine = H(2)O + pyridoxine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01915	H(2)O + acceptor + spermidine = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01920	S-adenosylmethioninamine + putrescine = S-methyl-5'-thioadenosine + spermidine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01936	2-oxaloglutaric acid = 2-oxoadipate + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01939	2-oxoglutarate + L-alpha-aminoadipate = 2-oxoadipate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01940	2-oxoadipate + Enzyme N6-(lipoyl)lysine = CO(2) + S(8)-glutaryldihydrolipoamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01954	ATP + L-aspartate + L-citrulline = (N(omega)-L-arginino)succinate + AMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01956	2-oxoglutarate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01959	H(2)O + N-formyl-N-kynurenine = L-kynurenine + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01960	H(+) + L-kynurenine + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01978	(S)-3-hydroxy-3-methylglutaryl-CoA + CoA = H(2)O + acetoacetyl-CoA + acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR01993	(S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02003	geranyl diphosphate + isopentenyl diphosphate = diphosphate + farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02013	geranyl diphosphate = (4S)-limonene + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02021	3'-phospho-5'-adenylyl sulfate + thioredoxin = adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02029	H(2)O + phosphatidylglycerophosphate = phosphate + phosphatidylglycerol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02035	D-glucono-1,5-lactone 6-phosphate + H(2)O = 6-phospho-D-gluconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02037	S-adenosyl-L-methionine + phosphoethanolamine = N-methylethanolamine phosphate + S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02038	CTP + phosphoethanolamine = CDP-ethanolamine + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02055	phosphatidylserine = CO(2) + phosphatidylethanolamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02057	1,2-diacyl-sn-glycerol + CDP-ethanolamine = CMP + phosphatidylethanolamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02058	acetyl-CoA + alpha-D-glucosamine 6-phosphate = CoA + N-acetyl-D-glucosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02059	H(2)O + N-acetyl-D-glucosamine 6-phosphate = acetate + alpha-D-glucosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02060	alpha-D-glucosamine 1-phosphate = alpha-D-glucosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02061	farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02065	2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02080	L-dopa = CO(2) + dopamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02081	(R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02082	(R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02085	(S)-3-hydroxy-3-methylglutaryl-CoA = 3-methylglutaconyl-CoA + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02087	N-acetyl-D-glucosamine 6-phosphate = N-acetyl-D-mannosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02100	H(2)O + dUTP = dUMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02103	H(2)O + NAD(+) + xanthine = H(+) + NADH + urate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02106	H(2)O + O(2) + urate = 5-hydroxyisouric acid + H(2)O(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02133	H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02134	ATP + thiamine = ADP + thiamine phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02139	H(2)O + barbiturate = 3-oxo-3-ureidopropanoic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02142	XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02164	Quinone + succinate = Hydroquinone + fumarate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02199	2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02236	7,8-dihydrofolate + NADP(+) = H(+) + NADPH + folate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02237	7,8-dihydropteroate + ATP + L-glutamate = 7,8-dihydrofolate + ADP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02241	CoA + phosphatidate = 1-acyl-sn-glycerol 3-phosphate + acyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02245	(R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02253	H(+) + NADPH + O(2) + trans-cinnamate = H(2)O + NADP(+) + trans-4-coumarate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02262	L-fuculose 1-phosphate = L-lactaldehyde + glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02263	L-rhamnulose 1-phosphate = L-lactaldehyde + glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02272	5-aminolevulinate = (S)-4-amino-5-oxopentanoic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02274	2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02276	5-acetamidopentanoate + H(2)O = 5-aminopentanoate + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02278	2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02279	5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + CO(2) + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02282	L-glutamate + N(2)-acetyl-L-ornithine = L-ornithine + N-acetyl-L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02283	2-oxoglutarate + N(2)-acetyl-L-ornithine = L-glutamate + N-acetyl-L-glutamate 5-semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02285	H(2)O + N-formimidoyl-L-glutamate = L-glutamate + formamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02286	H(2)O + N-formimidoyl-L-glutamate = N-formyl-L-glutamate + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02287	5-formiminotetrahydrofolate + L-glutamate = 5,6,7,8-tetrahydrofolate + N-formimidoyl-L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02288	4-imidazolone-5-propanoate + H(2)O = N-formimidoyl-L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02291	L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02305	farnesyl diphosphate = diphosphate + pentalenene	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02307	farnesyl diphosphate = aristolochene + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02313	H(2)O + NAD(+) + saccharopine = H(+) + L-2-aminoadipate 6-semialdahyde + L-glutamate + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02315	H(2)O + NADP(+) + saccharopine = H(+) + L-2-aminoadipate 6-semialdahyde + L-glutamate + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02325	H(2)O + dCTP = NH(3) + dUTP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02340	indoleglycerol phosphate = D-glyceraldehyde 3-phosphate + indole	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02362	n H(2)O + pectin = n methanol + pectate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02401	5-oxopentanoate + H(2)O + NAD(+) = H(+) + NADH + glutarate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02412	ATP + shikimate = 3-phosphoshikimate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02413	NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02422	H(2)O + allantoate = (S)-ureidoglycolate + urea	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02423	H(2)O + allantoate = 2-ureidoglycine + CO(2) + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02425	(S)-allantoin + H(2)O = allantoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02426	CDP-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02437	L-rhamnose = L-rhamnulose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02439	ATP + L-ribulose = ADP + L-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02466	3-sulfino-L-alanine = CO(2) + hypotaurine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02467	2-aminoethanethiol + O(2) = hypotaurine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02472	(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02473	(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02493	ATP + pyridoxamine = ADP + pyridoxamine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02494	phosphate + pyridoxamine = H(2)O + pyridoxamine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02519	O(2) + homogentisate = 4-maleylacetoacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02521	(4-hydroxyphenyl)pyruvate + O(2) = CO(2) + homogentisate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02522	L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02526	H(2)O + L-arabinono-1,4-lactone = L-arabinonate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02530	(R)-S-lactoylglutathione = glutathione + methylglyoxal	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02533	(R)-noradrenaline + S-adenosyl-L-methionine = (R)-adrenaline + S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02535	L-ascorbate + O(2) + dopamine = (R)-noradrenaline + H(2)O + L-dehydroascorbate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02536	H(2)O + NAD(+) + phenylacetaldehyde = H(+) + NADH + phenylacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02545	NAD(+) + meso-tartrate = 2-hydroxy-3-oxosuccinate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02549	4-aminobutanal + H(2)O + NAD(+) = 4-aminobutanoate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02553	NAD(+) + cyclopentanol = H(+) + NADH + cyclopentanone	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02554	H(+) + NADPH + O(2) + cyclopentanone = 5-valerolactone + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02565	H(2)O + NAD(+) + betaine aldehyde = 2 H(+) + NADH + betaine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02571	Enzyme N6-(dihydrolipoyl)lysine + glutaryl-CoA = CoA + S(8)-glutaryldihydrolipoamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02601	2-hydroxy-2,4-pentadienoate + H(2)O = 4-hydroxy-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02603	2-hydroxy-2,4-pentadienoate + succinate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02606	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(2)O = 2-hydroxy-2,4-pentadienoate + benzoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02613	2-phenylethylamine + H(2)O + O(2) = H(2)O(2) + NH(3) + phenylacetaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02649	ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02664	2-phospho-D-glycerate + ATP = 2,3-bisphospho-D-glycerate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02665	3-hydroxyanthranilate + O(2) = 2-amino-3-carboxymuconate semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02668	3-hydroxy-L-kynurenine + H(2)O = 3-hydroxyanthranilate + L-alanine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02698	4-hydroxyphenylacetate + H(+) + NADH + O(2) = (3,4-dihydroxyphenyl)acetate + H(2)O + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02701	5-hydroxy-L-tryptophan = CO(2) + serotonin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02705	ATP + N-acetyl-D-mannosamine = ADP + N-acetyl-D-mannosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02715	D-arabinono-1,4-lactone + O(2) = H(2)O(2) + dehydro-D-arabinono-1,4-lactone	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02733	H(2)O + N-acetyl-LL-2,6-diaminopimelate = LL-2,6-diaminopimelate + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02734	H(2)O + N-succinyl-LL-2,6-diaminopimelate = LL-2,6-diaminopimelate + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02735	LL-2,6-diaminopimelate = DL-2,6-diaminopimelate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02749	2-deoxy-alpha-D-ribose 1-phosphate = 2-deoxy-D-ribose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02752	D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02754	5-dehydro-4-deoxy-D-glucarate = 2-hydroxy-3-oxopropanoate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02755	DL-2,6-diaminopimelate + H(2)O + NADP(+) = (S)-2-amino-6-oxopimelate + H(+) + NADPH + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02765	(R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02782	scyllo-inosose = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02804	H(2)O + dinitrogen + 2 ferricytochrome c = 2 H(+) + 2 ferrocytochrome c + nitrous oxide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02821	L-homocysteine + betaine = L-methionine + N,N-dimethylglycine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02860	H(2)O + acceptor + nicotine = (S)-6-hydroxynicotine + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02864	2 H(+) + siroheme = Fe2+ + sirohydrochlorin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02869	S-adenosylmethioninamine + spermidine = S-methyl-5'-thioadenosine + spermine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02874	H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02911	acetyl-CoA + serotonin = CoA + N-acetylserotonin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02914	4-imidazolone-5-propanoate = H(2)O + trans-urocanate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02922	H(2)O + creatinine = N-methylhydantoin + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02933	H(2)O + L-gulono-1,4-lactone = L-gulonate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02935	(S)-ureidoglycolate + NAD(+) = H(+) + NADH + oxalurate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02936	(S)-ureidoglycolate + NADP(+) = H(+) + NADPH + oxalurate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02946	(R,R)-butane-2,3-diol + NAD(+) = (R)-acetoin + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02948	(S)-2-acetolactate = (R)-acetoin + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02988	3-oxoadipate + NAD(+) = H(+) + NADH + maleylacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02989	3-oxoadipate + NADP(+) = H(+) + NADPH + maleylacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02990	3-oxoadipate + succinyl-CoA = 3-oxoadipyl-CoA + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02991	5-oxo-4,5-dihydro-2-furylacetate + H(2)O = 3-oxoadipate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR02992	4-pyridoxolactone + H(2)O = 4-pyridoxate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03005	ATP + nicotinate D-ribonucleotide = deamido-NAD(+) + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03013	H(2)O + L-histidinol phosphate = L-histidinol + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03014	ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03015	H(2)O + N-formylmethanofuran + acceptor = CO(2) + methanofuran + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03018	(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03028	glutaconyl-1-CoA = CO(2) + crotonoyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03033	D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03035	ATP + pantotheine 4'-phosphate = 3'-dephospho-CoA + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03067	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03069	H(2)O + dimethylmaleate = (2R,3S)-2,3-dimethylmalate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03070	2-methylene-3-methylsuccinate = dimethylmaleate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03083	7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03084	3-dehydroquinate = 3-dehydroshikimate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03098	ATP + L-alpha-aminoadipate = alpha-aminoadipoyl-C6-AMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03102	H(2)O + L-2-aminoadipate 6-semialdahyde + NAD(+) = H(+) + L-alpha-aminoadipate + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03103	H(2)O + L-2-aminoadipate 6-semialdahyde + NADP(+) = H(+) + L-alpha-aminoadipate + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03119	NAD(+) + propane-1,3-diol = 3-hydroxypropanal + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03130	N-acetylserotonin + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + melatonin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03163	L-fucose = L-fuculose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03164	6-hydroxynicotinate + reduced ferredoxin = 6-hydroxynicotinate + oxidized ferredoxin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03165	hydroxymethylbilane = H(2)O + uroporphyrinogen III	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03181	4-maleylacetoacetate = 4-fumarylacetoacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03182	7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03184	L-gulono-1,4-lactone + O(2) = H(2)O(2) + L-xylo-hexulonolactone	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03187	ATP + 2 H(2)O + N-methylhydantoin = ADP + N-carbamoylsarcosine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03194	2 S-adenosyl-L-methionine + uroporphyrinogen III = 2 S-adenosyl-L-homocysteine + precorrin-2	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03197	uroporphyrinogen III = 4 CO(2) + coproporphyrinogen-III	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03199	(S)-2,3-epoxysqualene = lanosterol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03202	(S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03209	ATP + CoA + pimelate = AMP + diphosphate + pimeloyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03210	L-alanine + pimeloyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03217	L-cysteine + O-acetyl-L-homoserine = L-cystathionine + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03220	O(2) + coproporphyrinogen-III = 2 CO(2) + 2 H(2)O + protoporphyrinogen-IX	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03222	3 O(2) + protoporphyrinogen-IX = 3 H(2)O(2) + protoporphyrin-IX	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03223	4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole = diphosphate + thiamine phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03230	acetyl-CoA + deacetylvindoline = CoA + vindoline	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03231	8-amino-7-oxononanoate + S-adenosyl-L-methionine = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03236	ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03240	D-galactose 6-phosphate = D-tagatose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03241	ATP + L-fuculose = ADP + L-fuculose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03243	2-oxoglutarate + L-histidinol phosphate = L-glutamate + imidazole-acetol phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03244	L-ribulose 5-phosphate = L-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03245	(R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03254	8-phospho-3-deoxy-D-manno-octulosonate + phosphate = D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03256	H(2)O + lactose 6-phosphate = D-galactose 6-phosphate + beta-D-glucose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03260	L-cysteine + O-succinyl-L-homoserine = L-cystathionine + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03269	N-[(R)-4-phosphonopantothenoyl]-L-cysteine = CO(2) + pantotheine 4'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03298	2,3-bisphospho-D-glycerate + ATP = ADP + cyclic 2,3-diphosphoglycerate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03303	(3,4-dihydroxyphenyl)acetate + O(2) = 5-carboxymethyl-2-hydroxymuconate semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03307	2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03308	3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03313	L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03314	L-glutamate 5-semialdehyde = (S)-1-pyrroline-5-carboxylic acid + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03348	CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + quinolinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03350	8-phospho-3-deoxy-D-manno-octulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03351	3-deoxy-D-manno-octulosonate + CTP = CMP-3-deoxy-D-manno-octulosonate + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03387	2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonic acid + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03390	5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03391	CDP-4-dehydro-3,6-dideoxy-D-glucose + H(2)O + NAD(+) = CDP-4-dehydro-6-deoxy-D-glucose + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03392	CDP-4-dehydro-3,6-dideoxy-D-glucose + H(2)O + NADP(+) = CDP-4-dehydro-6-deoxy-D-glucose + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03409	H(2)O + guanosine 3'-diphosphate 5'-triphosphate = phosphate + ppGpp	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03418	1-alpha-D-galactosyl-myo-inositol + raffinose = myo-inositol + stachyose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03443	N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03444	(R)-homocitrate = H(2)O + homo-cis-aconitate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03445	4-(2-aminophenyl)-2,4-dioxobutanoate = H(2)O + kynurenate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03457	D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = H(2)O + imidazole-acetol phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03458	5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03459	2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + H(2)O = 5-amino-6-(5-phosphoribosylamino)uracil + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03460	3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03462	O(2) + biphenyl-2,3-diol = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03464	5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = H(+) + N(5)-formyl-5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03470	2-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 5-oxo-4,5-dihydro-2-furylacetate + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03471	4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03503	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03504	7,8-dihydroneopterin = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03508	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = CO(2) + H(2)O + indoleglycerol phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03509	N-(5-phospho-beta-D-ribosyl)anthranilic acid = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03534	2-hydroxyglutarate + FAD = 2-oxoglutarate + FADH2	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03543	H(+) + NADH + O(2) + benzene = NAD(+) + cis-1,2-dihydrobenzene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03559	H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03630	H(+) + NADH + O(2) + phthalate = NAD(+) + cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03693	L-citramalate = H(2)O + mesaconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03696	(2S,3S)-3-methyl-L-aspartate = NH(3) + mesaconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03721	S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + palmatine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03738	3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03791	(S)-mandelate = (R)-mandelate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03793	(S)-mandelate + acceptor = phenylglyoxylate + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03831	(S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03832	(S)-3'-hydroxy-N-methylcoclaurine + S-adenosyl-L-methionine = (S)-reticuline + H(+) + S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03892	maleylacetate = 3-hydroxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03896	(R)-citramalate = 2-methylmaleate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03898	2-methylmaleate + H(2)O = D-erythro-3-methylmalic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03908	2-methyleneglutarate = 2-methylene-3-methylsuccinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03932	4-chlorobenzoate + ATP + CoA = 4-chlorobenzoyl-CoA + AMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03937	H(2)O + glutaconyl-1-CoA = 2-hydroxyglutaryl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03947	NAD(+) + precorrin-2 = H(+) + NADH + sirohydrochlorin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03948	S-adenosyl-L-methionine + precorrin-2 = H(+) + S-adenosyl-L-homocysteine + precorrin-3A	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR03968	(2S)-2-isopropylmalate = 2-isopropylmaleate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04000	2-hydroxyglutarate + acetyl-CoA = 2-hydroxyglutaryl-CoA + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04001	(2R,3S)-3-isopropylmalate = 2-isopropylmaleate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04013	3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + desacetoxyvindoline	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04029	2-oxoglutarate + N(6)-acetyl-L-lysine = 6-acetamido-2-oxohexanoate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04030	2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04031	2-succinylbenzoate + H(2)O = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04035	1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphoribosyl)-5'-AMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04037	1-(5-phosphoribosyl)-5'-AMP + H(2)O = 5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04061	O(2) + benzene-1,2,4-triol = 3-hydroxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04088	(1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+) = 3-methylcatechol + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04095	3-isovaleryl-CoA + FAD = 3-methylcrotonyl-CoA + FADH2	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04101	4-chlorobenzoyl-CoA + H(2)O = 4-hydroxybenzoyl-CoA + H(+) + chloride	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04109	H(+) + L-glutamyl-tRNA(Glu) + NADPH = (S)-4-amino-5-oxopentanoic acid + NADP(+) + tRNA(Glu)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04138	3-methylcrotonyl-CoA + ATP + bicarbonate = 3-methylglutaconyl-CoA + ADP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04142	5-acetamidopentanoate + CO(2) + H(+) + NADH = 6-acetamido-2-oxohexanoate + H(2)O + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04143	5-methylthio-alpha-D-ribose + ATP = ADP + S-methyl-5-thio-alpha-D-ribose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04144	5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + N(1)-(5-phospho-D-ribosyl)glycinamide + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04148	5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = H(+) + alpha-ribazole 5'-phosphate + nicotinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04173	2-oxoglutarate + O-phospho-L-serine = 3-phosphohydroxypyruvate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04189	2 H(2)O + N(2)-succinyl-L-arginine = CO(2) + N(2)-succinyl-L-ornithine + 2 NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04198	(S)-tetrahydrodipicolinate + H(2)O + NAD(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04199	(S)-tetrahydrodipicolinate + H(2)O + NADP(+) = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04208	2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04209	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04210	4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04217	2-oxoglutarate + N(2)-succinyl-L-ornithine = L-glutamate + N-succinyl-L-glutamate 5-semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04218	prephytoene diphosphate = 15-cis-phytoene + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04231	(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + N-[(R)-4-phosphonopantothenoyl]-L-cysteine + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04265	CDP-3,6-dideoxy-D-glucose + NADP(+) = CDP-4-dehydro-3,6-dideoxy-D-glucose + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04266	CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04285	6-lactoyl-5,6,7,8-tetrahydropterin + NADP(+) = 6-pyruvoyl-tetrahydropterin + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04286	7,8-dihydroneopterin triphosphate = 6-pyruvoyl-tetrahydropterin + triphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04292	2 H(2)O + phosphate + quinolinate = glycerone phosphate + iminoaspartate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04293	H(2)O + quinolinate = 2-amino-3-carboxymuconate semialdehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04296	(S)-4-hydroxymandelonitrile + UDP-alpha-D-glucose = UDP + dhurrin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04325	10-formyl-5,6,7,8-tetrahydrofolate + N(1)-(5-phospho-D-ribosyl)glycinamide = 5,6,7,8-tetrahydrofolate + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04336	(S)-2-amino-6-oxopimelate = (S)-tetrahydrodipicolinate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04347	5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04364	(S)-tetrahydrodipicolinate + H(2)O + acetyl-CoA = (S)-2-acetamido-6-oxopimelate + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04365	(S)-tetrahydrodipicolinate + H(2)O + succinyl-CoA = CoA + L-2-succinylamino-6-oxopimelate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04371	homoisocitrate = H(2)O + homo-cis-aconitate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04376	3-(2,3-dihydroxyphenyl)propanoate + O(2) = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04379	5-carboxymethyl-2-hydroxymuconic acid = 5-oxopent-3-ene-1,2,5-tricarboxylic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04380	5-oxopent-3-ene-1,2,5-tricarboxylic acid = 2-hydroxy-hept-2,4-diene-1,7-dioic acid + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04382	4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonic acid = 2 5-dehydro-4-deoxy-D-glucuronic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04383	5-dehydro-4-deoxy-D-glucuronic acid = 3-deoxy-D-glycero-hexo-2,5-diulosonate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04390	H(+) + NADPH + alpha-aminoadipoyl-S-acyl enzyme = L-2-aminoadipate 6-semialdahyde + NADP(+) + holo-Lys2	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04393	lactose + protein N(pi)-phospho-L-histidine = lactose 6-phosphate + protein-L-histidine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04405	5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04418	5-carboxymethyl-2-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 5-carboxymethyl-2-hydroxymuconic acid + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04420	S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04426	(2R,3S)-3-isopropylmalate + NAD(+) = 3-carboxy-4-methyl-2-oxopentanoate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04427	S-adenosyl-L-methionine + zymosterol = S-adenosyl-L-homocysteine + fecosterol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04440	(R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = 2-oxo-3-hydroxyisovalerate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04441	(R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04448	5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04455	5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylene-5,6,7,8-tetrahydromethanopterin + H(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04456	5,10-methylene-5,6,7,8-tetrahydromethanopterin + coenzyme F420 = 1,5-dihydro-coenzyme F(420) + 5,10-methenyl-5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04457	2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + 2 H(2)O + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04463	ATP + H(2)O + L-glutamine + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide = 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + ADP + L-glutamate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04464	1,5-dihydro-coenzyme F(420) + 5,10-methylene-5,6,7,8-tetrahydromethanopterin = 5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme F420	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04467	2-oxoglutarate + N-acetyl-LL-2,6-diaminopimelate = (S)-2-acetamido-6-oxopimelate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04475	2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04509	4-amino-2-methyl-5-phosphomethylpyrimidine + ATP = 4-amino-2-methyl-5-diphosphomethylpyrimidine + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04540	coenzyme M-coenzyme B heterodisulfide + dihydromethanophenazine = coenzyme B + coenzyme M + methanophenazine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04541	coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04549	H(2)O + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = UMP + lipid X	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04550	(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine = UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + acyl-carrier protein	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04558	5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04559	(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + fumarate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04560	10-formyl-5,6,7,8-tetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = 5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04567	(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + UDP-N-acetyl-alpha-D-glucosamine = UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + acyl-carrier protein	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04587	H(2)O + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine = UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04591	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid + ADP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04594	H(2)O + alpha-ribazole 5'-phosphate = alpha-ribazole + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04606	UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + lipid X = 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + UDP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04621	7,8-dihydroneopterin + phosphate = 7,8-dihydroneopterin 3'-phosphate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04638	7,8-dihydroneopterin triphosphate + H(2)O = 7,8-dihydroneopterin 3'-phosphate + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04639	7,8-dihydroneopterin triphosphate + H(2)O = 2,5-diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04640	5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide = 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04657	2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + ATP = ADP + lipid IV(A)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04658	CMP-3-deoxy-D-manno-octulosonate + lipid IV(A) = 3-deoxy-D-manno-octulosonyl-lipid IV((A)) + CMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04672	(S)-2-acetolactate + thiamine diphosphate = 2-hydroxyethyl-ThPP + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04673	2-hydroxyethyl-ThPP + 2-oxobutanoate = (S)-2-acetyl-2-hydroxybutanoic acid + thiamine diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04692	(S)-coclaurine + S-adenosyl-L-methionine = (S)-N-methylcoclaurine + H(+) + S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04694	2 H(2)O + NADP(+) + berbamunine = (R)-N-methylcoclaurine + (S)-N-methylcoclaurine + H(+) + NADPH + O(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04862	NAD(+) + homoisocitrate = 2-oxaloglutaric acid + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04863	alpha-aminoadipoyl-C6-AMP + holo-Lys2 = AMP + alpha-aminoadipoyl-S-acyl enzyme	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04868	H(2)O + isopenicillin N + phenylacetyl-CoA = CoA + L-alpha-aminoadipate + penicillin G	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR04870	3 ATP + H(2)O + L-alpha-aminoadipate + L-cysteine + L-valine = 3 AMP + N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/GO_0003824	catalytic activity	http://purl.obolibrary.org/obo/GO_0003674	molecular_function		
http://purl.obolibrary.org/obo/GO_0016740	transferase activity	http://purl.obolibrary.org/obo/GO_0003824	catalytic activity		
http://purl.obolibrary.org/obo/GO_0016772	transferase activity, transferring phosphorus-containing groups	http://purl.obolibrary.org/obo/GO_0016740	transferase activity		
http://purl.obolibrary.org/obo/GO_0016301	kinase activity	http://purl.obolibrary.org/obo/GO_0016772	transferase activity, transferring phosphorus-containing groups		
http://purl.obolibrary.org/obo/UPa_UER00002	beta-alanine from L-aspartate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate => 1 CO(2) + 1 beta-alanine.
http://purl.obolibrary.org/obo/UPa_UER00003	(R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-methyl-2-oxobutanoate + 1 5,10-methylene-THF + 1 H(2)O => 1 2-dehydropantoate + 1 5,6,7,8-tetrahydrofolate.
http://purl.obolibrary.org/obo/UPa_UER00004	(R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-dehydropantoate + 1 H(+) + 1 NADPH => 1 (R)-pantoate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00005	(R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-pantoate + 1 ATP + 1 beta-alanine => 1 (R)-pantothenate + 1 AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00006	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 ATP => 1 1-(5-phospho-D-ribosyl)-ATP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00007	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-(5-phospho-D-ribosyl)-ATP + 1 H(2)O => 1 1-(5-phosphoribosyl)-5'-AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00008	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-(5-phosphoribosyl)-5'-AMP + 1 H(2)O => 1 5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide.
http://purl.obolibrary.org/obo/UPa_UER00009	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide => 1 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide.
http://purl.obolibrary.org/obo/UPa_UER00010	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + 1 L-glutamine => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00011	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate => 1 H(2)O + 1 imidazole-acetol phosphate.
http://purl.obolibrary.org/obo/UPa_UER00012	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 imidazole-acetol phosphate => 1 2-oxoglutarate + 1 L-histidinol phosphate.
http://purl.obolibrary.org/obo/UPa_UER00013	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-histidinol phosphate => 1 L-histidinol + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00014	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-histidinol + 2 NAD(+) => 2 H(+) + 1 L-histidine + 2 NADH.
http://purl.obolibrary.org/obo/UPa_UER00015	(S)-tetrahydrodipicolinate from L-aspartate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-aspartate => 1 4-phospho-L-aspartate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00016	(S)-tetrahydrodipicolinate from L-aspartate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-phospho-L-aspartate + 1 H(+) + 1 NADPH => 1 L-aspartate 4-semialdehyde + 1 NADP(+) + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00017	(S)-tetrahydrodipicolinate from L-aspartate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate 4-semialdehyde + 1 pyruvate => 1 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00018	(S)-tetrahydrodipicolinate from L-aspartate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + [NADH or NADPH] => (S)-tetrahydrodipicolinate + H(2)O + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00019	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-tetrahydrodipicolinate + 1 H(2)O + 1 succinyl-CoA => 1 CoA + 1 L-2-succinylamino-6-oxopimelate.
http://purl.obolibrary.org/obo/UPa_UER00020	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-2-succinylamino-6-oxopimelate + 1 L-glutamate => 1 2-oxoglutarate + 1 N-succinyl-LL-2,6-diaminopimelate.
http://purl.obolibrary.org/obo/UPa_UER00021	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-succinyl-LL-2,6-diaminopimelate => 1 LL-2,6-diaminopimelate + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00022	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-tetrahydrodipicolinate + 1 H(2)O + 1 acetyl-CoA => 1 (S)-2-acetamido-6-oxopimelate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00023	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-2-acetamido-6-oxopimelate + 1 L-glutamate => 1 2-oxoglutarate + 1 N-acetyl-LL-2,6-diaminopimelate.
http://purl.obolibrary.org/obo/UPa_UER00024	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-acetyl-LL-2,6-diaminopimelate => 1 LL-2,6-diaminopimelate + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00025	DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 LL-2,6-diaminopimelate => 1 DL-2,6-diaminopimelate.
http://purl.obolibrary.org/obo/UPa_UER00026	DL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-tetrahydrodipicolinate + 1 H(+) + 1 H(2)O + 1 NADPH + 1 NH(3) => 1 DL-2,6-diaminopimelate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00027	L-lysine from DL-2,6-diaminopimelate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 DL-2,6-diaminopimelate => 1 CO(2) + 1 L-lysine.
http://purl.obolibrary.org/obo/UPa_UER00028	L-alpha-aminoadipate from 2-oxoglutarate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 H(2)O + 1 acetyl-CoA => 1 (R)-homocitrate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00029	L-alpha-aminoadipate from 2-oxoglutarate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-homocitrate => 1 H(2)O + 1 homo-cis-aconitate.
http://purl.obolibrary.org/obo/UPa_UER00030	L-alpha-aminoadipate from 2-oxoglutarate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 homoisocitrate => 1 2-oxoadipate + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00031	L-alpha-aminoadipate from 2-oxoglutarate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoadipate + 1 L-glutamate => 1 2-oxoglutarate + 1 L-alpha-aminoadipate.
http://purl.obolibrary.org/obo/UPa_UER00032	L-lysine from L-alpha-aminoadipate (fungal route): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 H(+) + 1 L-alpha-aminoadipate + 1 NADPH => 1 AMP + 1 L-2-aminoadipate 6-semialdahyde + 1 NADP(+) + 1 diphosphate + 1 holo-Lys2.
http://purl.obolibrary.org/obo/UPa_UER00033	L-lysine from L-alpha-aminoadipate (fungal route): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-2-aminoadipate 6-semialdahyde + 1 L-glutamate + 1 NADPH => 1 H(2)O + 1 NADP(+) + 1 saccharopine.
http://purl.obolibrary.org/obo/UPa_UER00034	L-lysine from L-alpha-aminoadipate (fungal route): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 saccharopine => 1 2-oxoglutarate + 1 H(+) + 1 L-lysine + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00035	L-lysine from L-alpha-aminoadipate (Thermus route): step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-alpha-aminoadipate + 1 [LysW] => 1 ADP + 1 [LysW]-L-2-aminoadipate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00036	L-lysine from L-alpha-aminoadipate (Thermus route): step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 [LysW]-L-2-aminoadipate => 1 ADP + 1 [LysW]-L-2-aminoadipyl 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00037	L-lysine from L-alpha-aminoadipate (Thermus route): step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 [LysW]-L-2-aminoadipyl 6-phosphate => 1 NADP(+) + 1 [LysW]-L-2-aminoadipate 6-semialdehyde + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00038	L-lysine from L-alpha-aminoadipate (Thermus route): step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 [LysW]-L-2-aminoadipate 6-semialdehyde => 1 2-oxoglutarate + 1 [LysW]-L-lysine.
http://purl.obolibrary.org/obo/UPa_UER00039	L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 [LysW]-L-lysine => 1 L-lysine + 1 [LysW].
http://purl.obolibrary.org/obo/UPa_UER00040	L-tryptophan from chorismate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamine + 1 NH(3) + 1 chorismate => 1 L-glutamate + 1 anthranilate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00041	L-tryptophan from chorismate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 anthranilate => 1 N-(5-phospho-beta-D-ribosyl)anthranilic acid + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00042	L-tryptophan from chorismate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-(5-phospho-beta-D-ribosyl)anthranilic acid => 1 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00043	L-tryptophan from chorismate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate => 1 CO(2) + 1 H(2)O + 1 indoleglycerol phosphate.
http://purl.obolibrary.org/obo/UPa_UER00044	L-tryptophan from chorismate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-serine + 1 indoleglycerol phosphate => 1 D-glyceraldehyde 3-phosphate + 1 H(2)O + 1 L-tryptophan.
http://purl.obolibrary.org/obo/UPa_UER00053	taxol from baccatin III: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-(3'R)-debenzoyltaxol + 1 benzoyl-CoA => 1 CoA + 1 taxol.
http://purl.obolibrary.org/obo/UPa_UER00054	2-oxobutanoate from L-threonine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-threonine => 1 2-oxobutanoate + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00055	L-isoleucine from 2-oxobutanoate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxyethyl-ThPP + 1 2-oxobutanoate => 1 (S)-2-acetyl-2-hydroxybutanoic acid + 1 thiamine diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00056	L-isoleucine from 2-oxobutanoate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-2-acetyl-2-hydroxybutanoic acid + 1 H(+) + 1 NADPH => 1 (2R,3R)-2,3-dihydroxy-3-methylpentanoic acid + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00057	L-isoleucine from 2-oxobutanoate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2R,3R)-2,3-dihydroxy-3-methylpentanoic acid => 1 (S)-3-methyl-2-oxopentanoate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00058	L-isoleucine from 2-oxobutanoate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-3-methyl-2-oxopentanoate + 1 L-glutamate => 1 2-oxoglutarate + 1 L-isoleucine.
http://purl.obolibrary.org/obo/UPa_UER00059	L-valine from pyruvate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 pyruvate => 1 (S)-2-acetolactate + 1 CO(2) + 1 thiamine diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00060	L-valine from pyruvate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-2-acetolactate + 1 H(+) + 1 NADPH => 1 (R)-2,3-dihydroxy-3-methylbutanoate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00061	L-valine from pyruvate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-2,3-dihydroxy-3-methylbutanoate => 1 3-methyl-2-oxobutanoate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00062	L-valine from pyruvate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-methyl-2-oxobutanoate + 1 L-glutamate => 1 2-oxoglutarate + 1 L-valine.
http://purl.obolibrary.org/obo/UPa_UER00063	L-threonine from L-aspartate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		H(+) + L-aspartate 4-semialdehyde + [NADH or NADPH] => L-homoserine + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00064	L-threonine from L-aspartate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-homoserine => 1 ADP + 1 O-phospho-L-homoserine.
http://purl.obolibrary.org/obo/UPa_UER00065	L-threonine from L-aspartate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O-phospho-L-homoserine => 1 L-threonine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00066	2-oxobutanoate from pyruvate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acetyl-CoA + 1 pyruvate => 1 (R)-citramalate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00067	2-oxobutanoate from pyruvate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-citramalate => 1 D-erythro-3-methylmalic acid.
http://purl.obolibrary.org/obo/UPa_UER00069	2-oxobutanoate from pyruvate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-erythro-3-methylmalic acid + 1 NAD(+) => 1 2-oxobutanoate + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00070	L-leucine from 3-methyl-2-oxobutanoate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-methyl-2-oxobutanoate + 1 H(2)O + 1 acetyl-CoA => 1 (2S)-2-isopropylmalate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00071	L-leucine from 3-methyl-2-oxobutanoate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2S)-2-isopropylmalate => 1 (2R,3S)-3-isopropylmalate.
http://purl.obolibrary.org/obo/UPa_UER00072	L-leucine from 3-methyl-2-oxobutanoate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2R,3S)-3-isopropylmalate + 1 NAD(+) => 1 4-methyl-2-oxopentanoate + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00073	L-leucine from 3-methyl-2-oxobutanoate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-methyl-2-oxopentanoate + 1 L-glutamate => 1 2-oxoglutarate + 1 L-leucine.
http://purl.obolibrary.org/obo/UPa_UER00074	O-acetyl-L-homoserine from L-homoserine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-homoserine + 1 acetyl-CoA => 1 CoA + 1 O-acetyl-L-homoserine.
http://purl.obolibrary.org/obo/UPa_UER00075	O-succinyl-L-homoserine from L-homoserine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-homoserine + 1 succinyl-CoA => 1 CoA + 1 O-succinyl-L-homoserine.
http://purl.obolibrary.org/obo/UPa_UER00076	L-homocysteine from S-adenosyl-L-homocysteine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 S-adenosyl-L-homocysteine => 1 L-homocysteine + 1 adenosine.
http://purl.obolibrary.org/obo/UPa_UER00077	L-cystathionine from O-succinyl-L-homoserine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-cysteine + 1 O-succinyl-L-homoserine => 1 L-cystathionine + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00078	L-homocysteine from L-cystathionine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-cystathionine => 1 L-homocysteine + 1 NH(3) + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00079	L-homocysteine from O-acetyl-L-homoserine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O-acetyl-L-homoserine + 1 hydrogen sulfide => 1 L-homocysteine + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00080	S-adenosyl-L-methionine from L-methionine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 H(2)O + 1 L-methionine => 1 S-adenosyl-L-methionine + 1 diphosphate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00081	L-methionine from L-homocysteine (MetH route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-methyl-THF + 1 L-homocysteine => 1 5,6,7,8-tetrahydrofolate + 1 L-methionine.
http://purl.obolibrary.org/obo/UPa_UER00082	L-methionine from L-homocysteine (MetE route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-methyltetrahydropteroyltri-L-glutamate + 1 L-homocysteine => 1 L-methionine + 1 tetrahydropteroyltri-L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00083	L-methionine from L-homocysteine (BhmT route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-homocysteine + 1 betaine => 1 L-methionine + 1 N,N-dimethylglycine.
http://purl.obolibrary.org/obo/UPa_UER00084	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 1/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-erythrose 4-phosphate + 1 H(2)O + 1 phosphoenolpyruvate => 1 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00085	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate => 1 3-dehydroquinate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00086	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-dehydroquinate => 1 3-dehydroshikimate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00087	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-dehydroshikimate + 1 H(+) + 1 NADPH => 1 NADP(+) + 1 shikimate.
http://purl.obolibrary.org/obo/UPa_UER00088	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 shikimate => 1 3-phosphoshikimate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00089	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-phosphoshikimate + 1 phosphoenolpyruvate => 1 5-O-(1-carboxyvinyl)-3-phosphoshikimate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00090	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-O-(1-carboxyvinyl)-3-phosphoshikimate => 1 chorismate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00091	1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glyceraldehyde 3-phosphate + 1 pyruvate => 1 1-deoxy-D-xylulose 5-phosphate + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00092	isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-deoxy-D-xylulose 5-phosphate + 1 H(+) + 1 NADPH => 1 2-C-methyl-D-erythritol 4-phosphate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00093	isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-C-methyl-D-erythritol 4-phosphate + 1 CTP => 1 4-CDP-2-C-methyl-D-erythritol + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00094	isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-CDP-2-C-methyl-D-erythritol + 1 ATP => 1 4-CDP-2-C-methyl-D-erythritol 2-phosphate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00095	isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-CDP-2-C-methyl-D-erythritol 2-phosphate => 1 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + 1 CMP.
http://purl.obolibrary.org/obo/UPa_UER00096	isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + 2 reduced ferredoxin => 1 (2E)-4-hydroxy-3-methylbutenyl diphosphate + 1 H(2)O + 2 oxidized ferredoxin.
http://purl.obolibrary.org/obo/UPa_UER00097	isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2E)-4-hydroxy-3-methylbutenyl diphosphate + 1 H(+) + 1 NADPH => 1 H(2)O + 1 NADP(+) + 1 isopentenyl diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00098	isopentenyl diphosphate from (R)-mevalonate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-mevalonate + 1 ATP => 1 (R)-5-phosphomevalonate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00099	isopentenyl diphosphate from (R)-mevalonate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-5-phosphomevalonate + 1 ATP => 1 (R)-5-diphosphomevalonate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00100	isopentenyl diphosphate from (R)-mevalonate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-5-diphosphomevalonate + 1 ATP => 1 ADP + 1 CO(2) + 1 isopentenyl diphosphate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00101	(R)-mevalonate from acetyl-CoA: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		2 acetyl-CoA => 1 CoA + 1 acetoacetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00102	(R)-mevalonate from acetyl-CoA: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acetoacetyl-CoA + 1 acetyl-CoA => 1 (S)-3-hydroxy-3-methylglutaryl-CoA + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00103	(R)-mevalonate from acetyl-CoA: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH => 1 (R)-mevalonate + 1 CoA + 2 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00104	dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 isopentenyl diphosphate => 1 dimethylallyl diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00105	dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2E)-4-hydroxy-3-methylbutenyl diphosphate + 1 H(+) + 1 NADPH => 1 H(2)O + 1 NADP(+) + 1 dimethylallyl diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00106	N(2)-acetyl-L-ornithine from L-glutamate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 acetyl-CoA => 1 CoA + 1 N-acetyl-L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00107	N(2)-acetyl-L-ornithine from L-glutamate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 N-acetyl-L-glutamate => 1 ADP + 1 N-acetyl-L-glutamyl 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00108	N(2)-acetyl-L-ornithine from L-glutamate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 N-acetyl-L-glutamyl 5-phosphate + 1 NADPH => 1 N-acetyl-L-glutamate 5-semialdehyde + 1 NADP(+) + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00109	N(2)-acetyl-L-ornithine from L-glutamate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 N-acetyl-L-glutamate 5-semialdehyde => 1 2-oxoglutarate + 1 N(2)-acetyl-L-ornithine.
http://purl.obolibrary.org/obo/UPa_UER00110	L-ornithine from N(2)-acetyl-L-ornithine (linear): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N(2)-acetyl-L-ornithine => 1 L-ornithine + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00111	L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 N(2)-acetyl-L-ornithine => 1 L-ornithine + 1 N-acetyl-L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00112	L-arginine from L-ornithine and carbamoyl phosphate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-ornithine + 1 carbamoyl phosphate => 1 L-citrulline + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00113	L-arginine from L-ornithine and carbamoyl phosphate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-aspartate + 1 L-citrulline => 1 (N(omega)-L-arginino)succinate + 1 AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00114	L-arginine from L-ornithine and carbamoyl phosphate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (N(omega)-L-arginino)succinate => 1 L-arginine + 1 fumarate.
http://purl.obolibrary.org/obo/UPa_UER00115	(S)-dihydroorotate from bicarbonate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		2 ATP + 1 H(2)O + 1 L-glutamine + 1 bicarbonate => 2 ADP + 1 L-glutamate + 1 carbamoyl phosphate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00116	(S)-dihydroorotate from bicarbonate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate + 1 carbamoyl phosphate => 1 N-carbamoyl-L-aspartate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00117	(S)-dihydroorotate from bicarbonate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-carbamoyl-L-aspartate => 1 (S)-dihydroorotate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00118	orotate from (S)-dihydroorotate (O2 route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-dihydroorotate + 1 fumarate => 1 orotate + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00119	UMP from orotate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 orotate => 1 diphosphate + 1 orotidine 5'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00120	UMP from orotate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 orotidine 5'-phosphate => 1 CO(2) + 1 UMP.
http://purl.obolibrary.org/obo/UPa_UER00121	L-ectoine from L-aspartate 4-semialdehyde: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate 4-semialdehyde + 1 L-glutamate => 1 2-oxoglutarate + 1 L-2,4-diaminobutanoate.
http://purl.obolibrary.org/obo/UPa_UER00122	L-ectoine from L-aspartate 4-semialdehyde: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-2,4-diaminobutanoate + 1 acetyl-CoA => 1 CoA + 1 N(4)-acetyl-L-2,4-diaminobutyric acid.
http://purl.obolibrary.org/obo/UPa_UER00123	L-ectoine from L-aspartate 4-semialdehyde: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N(4)-acetyl-L-2,4-diaminobutyric acid => 1 H(2)O + 1 L-ectoine.
http://purl.obolibrary.org/obo/UPa_UER00124	N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 H(2)O + 1 L-glutamine => 1 5-phospho-beta-D-ribosylamine + 1 L-glutamate + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00125	N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-beta-D-ribosylamine + 1 ATP + 1 glycine => 1 ADP + 1 N(1)-(5-phospho-D-ribosyl)glycinamide + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00126	N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 10-formyl-5,6,7,8-tetrahydrofolate + 1 N(1)-(5-phospho-D-ribosyl)glycinamide => 1 5,6,7,8-tetrahydrofolate + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide.
http://purl.obolibrary.org/obo/UPa_UER00127	N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 N(1)-(5-phospho-D-ribosyl)glycinamide + 1 formate => 1 ADP + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00128	5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 H(2)O + 1 L-glutamine + 1 N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide => 1 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + 1 ADP + 1 L-glutamate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00129	5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine + 1 ATP => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 ADP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00130	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 CO(2) => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.
http://purl.obolibrary.org/obo/UPa_UER00131	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 1 ATP + 1 L-aspartate => 1 (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid + 1 ADP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00132	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 fumarate.
http://purl.obolibrary.org/obo/UPa_UER00133	5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 10-formyl-5,6,7,8-tetrahydrofolate + 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide => 1 5,6,7,8-tetrahydrofolate + 1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
http://purl.obolibrary.org/obo/UPa_UER00134	5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 ATP + 1 formate => 1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 ADP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00135	IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide => 1 H(2)O + 1 IMP.
http://purl.obolibrary.org/obo/UPa_UER00136	4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-amino-1-(5-phospho-D-ribosyl)imidazole => 1 4-amino-5-hydroxymethyl-2-methylpyrimidine.
http://purl.obolibrary.org/obo/UPa_UER00137	4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-amino-5-hydroxymethyl-2-methylpyrimidine + 1 ATP => 1 4-amino-2-methyl-5-phosphomethylpyrimidine + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00138	4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-amino-2-methyl-5-phosphomethylpyrimidine + 1 ATP => 1 4-amino-2-methyl-5-diphosphomethylpyrimidine + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00139	4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-(2-hydroxyethyl)-4-methylthiazole + 1 ATP => 1 4-methyl-5-(2-phosphoethyl)-thiazole + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00140	4-methyl-5-(2-phosphoethyl)-thiazole from 1-deoxy-D-xylulose 5-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-deoxy-D-xylulose 5-phosphate => 1 4-methyl-5-(2-phosphoethyl)-thiazole.
http://purl.obolibrary.org/obo/UPa_UER00141	thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-amino-2-methyl-5-diphosphomethylpyrimidine + 1 4-methyl-5-(2-phosphoethyl)-thiazole => 1 diphosphate + 1 thiamine phosphate.
http://purl.obolibrary.org/obo/UPa_UER00142	thiamine diphosphate from thiamine phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 thiamine phosphate => 1 ADP + 1 thiamine diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00143	acetyl-CoA from myo-inositol: step 1/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 myo-inositol => 1 H(+) + 1 NADH + 1 scyllo-inosose.
http://purl.obolibrary.org/obo/UPa_UER00144	acetyl-CoA from myo-inositol: step 2/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 scyllo-inosose => 1 3D-3,5/4-trihydroxycyclohexane-1,2-dione + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00145	acetyl-CoA from myo-inositol: step 3/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3D-3,5/4-trihydroxycyclohexane-1,2-dione + 1 H(2)O => 1 5-deoxy-D-glucuronic acid.
http://purl.obolibrary.org/obo/UPa_UER00146	acetyl-CoA from myo-inositol: step 5/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-deoxy-5-keto-D-gluconic acid + 1 ATP => 1 6-phospho-5-dehydro-2-deoxy-D-gluconic acid + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00147	acetyl-CoA from myo-inositol: step 6/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-phospho-5-dehydro-2-deoxy-D-gluconic acid => 1 3-oxopropanoate + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00148	acetyl-CoA from myo-inositol: step 7/7	http://purl.obolibrary.org/obo/BFO_0000015	process		3-oxopropanoate + CoA + [NAD(+) or NADP(+)] => CO(2) + H(+) + acetyl-CoA + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00149	4-aminobenzoate from chorismate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamine + 1 NH(3) + 1 chorismate => 1 4-amino-4-deoxychorismate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00150	4-aminobenzoate from chorismate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-amino-4-deoxychorismate => 1 4-aminobenzoate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00151	7,8-dihydroneopterin triphosphate from GTP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GTP + 1 H(2)O => 1 7,8-dihydroneopterin triphosphate + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00152	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7,8-dihydroneopterin triphosphate + 1 H(2)O => 1 7,8-dihydroneopterin 3'-phosphate + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00153	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7,8-dihydroneopterin 3'-phosphate + 1 H(2)O => 1 7,8-dihydroneopterin + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00154	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7,8-dihydroneopterin => 1 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + 1 glycolaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00155	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + 1 ATP => 1 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 1 AMP.
http://purl.obolibrary.org/obo/UPa_UER00156	7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 1 4-aminobenzoate => 1 7,8-dihydropteroate + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00157	7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7,8-dihydropteroate + 1 ATP + 1 L-glutamate => 1 7,8-dihydrofolate + 1 ADP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00158	5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7,8-dihydrofolate + 1 H(+) + 1 NADPH => 1 5,6,7,8-tetrahydrofolate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00159	8-amino-7-oxononanoate from pimeloyl-CoA: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-alanine + 1 pimeloyl-CoA => 1 8-amino-7-oxononanoate + 1 CO(2) + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00160	7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 8-amino-7-oxononanoate + 1 S-adenosyl-L-methionine => 1 7,8-diaminononanoate + 1 S-adenosyl-4-methylthio-2-oxobutanoic acid.
http://purl.obolibrary.org/obo/UPa_UER00161	biotin from 7,8-diaminononanoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7,8-diaminononanoate + 1 ATP + 1 CO(2) => 1 ADP + 1 dethiobiotin + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00162	biotin from 7,8-diaminononanoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(+) + 2 S-adenosyl-L-methionine + 1 dethiobiotin + 2 e- + 1 sulfur donor => 2 5'-deoxyadenosine + 2 L-methionine + 1 biotin.
http://purl.obolibrary.org/obo/UPa_UER00163	1,4-dihydroxy-2-naphthoate from chorismate: step 1/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 chorismate => 1 isochorismate.
http://purl.obolibrary.org/obo/UPa_UER00164	1,4-dihydroxy-2-naphthoate from chorismate: step 2/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 isochorismate => 1 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00165	1,4-dihydroxy-2-naphthoate from chorismate: step 4/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid => 1 2-succinylbenzoate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00166	1,4-dihydroxy-2-naphthoate from chorismate: step 5/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-succinylbenzoate + 1 ATP + 1 CoA => 1 2-succinylbenzoyl-CoA + 1 AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00167	1,4-dihydroxy-2-naphthoate from chorismate: step 6/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-succinylbenzoyl-CoA => 1 1,4-dihydroxy-2-naphthoyl-CoA + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00168	menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,4-dihydroxy-2-naphthoate + 1 all-trans-polyprenyl diphosphate => 1 CO(2) + 1 demethylmenaquinol + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00169	menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 demethylmenaquinol => 1 S-adenosyl-L-homocysteine + 1 menaquinol.
http://purl.obolibrary.org/obo/UPa_UER00170	formate from 10-formyl-5,6,7,8-tetrahydrofolate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 10-formyl-5,6,7,8-tetrahydrofolate + 1 H(2)O => 1 5,6,7,8-tetrahydrofolate + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00171	carbamoyl phosphate from bicarbonate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 ATP + 1 H(2)O + 1 L-glutamine + 1 bicarbonate => 2 ADP + 1 L-glutamate + 1 carbamoyl phosphate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00172	5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-ribose 5-phosphate => 1 5-phospho-alpha-D-ribose 1-diphosphate + 1 AMP.
http://purl.obolibrary.org/obo/UPa_UER00173	5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-ribose 5-phosphate => 1 alpha-D-ribose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00174	5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 alpha-D-ribose 1-phosphate => 1 D-ribose 1,5-bisphosphate.
http://purl.obolibrary.org/obo/UPa_UER00175	5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-ribose 1,5-bisphosphate => 1 5-phospho-alpha-D-ribose 1-diphosphate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00176	3-dehydroquinate from D-quinate (NAD(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-quinate + 1 NAD(+) => 1 3-dehydroquinate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00177	3-dehydroquinate from D-quinate (PQQ route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-quinate + 1 pyrroloquinoline quinone => 1 3-dehydroquinate + 1 pyrroloquinoline quinol.
http://purl.obolibrary.org/obo/UPa_UER00178	3,4-dihydroxybenzoate from 3-dehydroquinate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-dehydroquinate => 1 3-dehydroshikimate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00179	3,4-dihydroxybenzoate from 3-dehydroquinate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-dehydroshikimate => 1 3,4-dihydroxybenzoate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00180	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-glucose => 1 ADP + 1 D-glucose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00181	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucose 6-phosphate => 1 D-fructose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00182	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-fructose 6-phosphate => 1 ADP + 1 D-fructose 1,6-bisphosphate.
http://purl.obolibrary.org/obo/UPa_UER00183	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-fructose 1,6-bisphosphate => 1 D-glyceraldehyde 3-phosphate + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00184	pyruvate from D-glyceraldehyde 3-phosphate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glyceraldehyde 3-phosphate + 1 NAD(+) + 1 phosphate => 1 3-phospho-D-glyceroyl phosphate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00185	pyruvate from D-glyceraldehyde 3-phosphate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-phospho-D-glyceroyl phosphate + 1 ADP => 1 3-phospho-D-glycerate + 1 ATP.
http://purl.obolibrary.org/obo/UPa_UER00186	pyruvate from D-glyceraldehyde 3-phosphate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-phospho-D-glycerate => 1 2-phospho-D-glycerate.
http://purl.obolibrary.org/obo/UPa_UER00187	pyruvate from D-glyceraldehyde 3-phosphate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-phospho-D-glycerate => 1 H(2)O + 1 phosphoenolpyruvate.
http://purl.obolibrary.org/obo/UPa_UER00188	pyruvate from D-glyceraldehyde 3-phosphate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ADP + 1 phosphoenolpyruvate => 1 ATP + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00189	D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 glycerone phosphate => 1 D-glyceraldehyde 3-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00190	GDP-L-fucose from GDP-alpha-D-mannose: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GDP-alpha-D-mannose => 1 GDP-4-dehydro-6-deoxy-D-mannose + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00191	GDP-L-fucose from GDP-alpha-D-mannose: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GDP-4-dehydro-6-deoxy-D-mannose + 1 H(+) + 1 NADPH => 1 GDP-L-fucose + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00192	2-(alpha-D-mannosyl)-D-glycerate from GDP-alpha-D-mannose (MPG route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-phospho-D-glycerate + 1 GDP-alpha-D-mannose => 1 2-(alpha-D-mannosyl)-3-phosphoglyceric acid + 1 GDP.
http://purl.obolibrary.org/obo/UPa_UER00193	2-(alpha-D-mannosyl)-D-glycerate from GDP-alpha-D-mannose (MPG route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-(alpha-D-mannosyl)-3-phosphoglyceric acid + 1 H(2)O => 1 2-(alpha-D-mannosyl)-D-glycerate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00194	L-asparagine from L-aspartate (ammonia route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-aspartate + 1 NH(3) => 1 AMP + 1 L-asparagine + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00195	L-asparagine from L-aspartate (L-Gln route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 H(2)O + 1 L-aspartate + 1 L-glutamine => 1 AMP + 1 L-asparagine + 1 L-glutamate + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00196	L-serine from 3-phospho-D-glycerate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-phospho-D-glycerate + 1 NAD(+) => 1 3-phosphohydroxypyruvate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00197	L-serine from 3-phospho-D-glycerate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-phosphohydroxypyruvate + 1 L-glutamate => 1 2-oxoglutarate + 1 O-phospho-L-serine.
http://purl.obolibrary.org/obo/UPa_UER00198	L-serine from 3-phospho-D-glycerate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O-phospho-L-serine => 1 L-serine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00199	L-cysteine from L-serine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-serine + 1 acetyl-CoA => 1 CoA + 1 O-acetyl-L-serine.
http://purl.obolibrary.org/obo/UPa_UER00200	L-cysteine from L-serine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O-acetyl-L-serine + 1 hydrogen sulfide => 1 L-cysteine + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00201	L-cysteine from L-homocysteine and L-serine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-homocysteine + 1 L-serine => 1 H(2)O + 1 L-cystathionine.
http://purl.obolibrary.org/obo/UPa_UER00202	L-cysteine from L-homocysteine and L-serine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-cystathionine => 1 2-oxobutanoate + 1 L-cysteine + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00203	prephenate from chorismate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 chorismate => 1 prephenate.
http://purl.obolibrary.org/obo/UPa_UER00204	sulfite from sulfate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 sulfate => 1 5'-adenylyl sulfate + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00205	sulfite from sulfate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5'-adenylyl sulfate + 1 ATP => 1 3'-phospho-5'-adenylyl sulfate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00206	sulfite from sulfate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3'-phospho-5'-adenylyl sulfate + 1 thioredoxin => 1 adenosine 3',5'-bisphosphate + 1 sulfite + 1 thioredoxin disulfide.
http://purl.obolibrary.org/obo/UPa_UER00207	hydrogen sulfide from sulfite (NADPH route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		3 H(+) + 3 NADPH + 1 sulfite => 3 H(2)O + 3 NADP(+) + 1 hydrogen sulfide.
http://purl.obolibrary.org/obo/UPa_UER00208	hydrogen sulfide from sulfite (ferredoxin route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		6 H(+) + 6 reduced ferredoxin + 1 sulfite => 3 H(2)O + 1 hydrogen sulfide + 6 oxidized ferredoxin.
http://purl.obolibrary.org/obo/UPa_UER00209	glutathione from L-cysteine and L-glutamate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-cysteine + 1 L-glutamate => 1 ADP + 1 L-gamma-glutamyl-L-cysteine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00210	glutathione from L-cysteine and L-glutamate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-gamma-glutamyl-L-cysteine + 1 glycine => 1 ADP + 1 glutathione + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00211	precorrin-2 from uroporphyrinogen III: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 S-adenosyl-L-methionine + 1 uroporphyrinogen III => 2 S-adenosyl-L-homocysteine + 1 precorrin-2.
http://purl.obolibrary.org/obo/UPa_UER00212	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 1/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 precorrin-2 => 1 H(+) + 1 S-adenosyl-L-homocysteine + 1 precorrin-3A.
http://purl.obolibrary.org/obo/UPa_UER00213	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 2/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 precorrin-3A => 1 H(2)O + 1 NAD(+) + 1 precorrin-3B.
http://purl.obolibrary.org/obo/UPa_UER00214	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 3/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 precorrin-3B => 1 S-adenosyl-L-homocysteine + 1 precorrin-4.
http://purl.obolibrary.org/obo/UPa_UER00215	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 4/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 precorrin-4 => 1 S-adenosyl-L-homocysteine + 1 precorrin-5.
http://purl.obolibrary.org/obo/UPa_UER00216	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 5/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 S-adenosyl-L-methionine + 1 precorrin-5 => 1 S-adenosyl-L-homocysteine + 1 acetate + 1 precorrin-6A.
http://purl.obolibrary.org/obo/UPa_UER00217	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 6/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 precorrin-6A => 1 NADP(+) + 1 precorrin-6B.
http://purl.obolibrary.org/obo/UPa_UER00218	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 7/10	http://purl.obolibrary.org/obo/BFO_0000015	process		2 S-adenosyl-L-methionine + 1 precorrin-6B => 1 CO(2) + 2 S-adenosyl-L-homocysteine + 1 precorrin-8X.
http://purl.obolibrary.org/obo/UPa_UER00219	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 8/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 precorrin-8X => 1 hydrogenobyrinic acid.
http://purl.obolibrary.org/obo/UPa_UER00220	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 9/10	http://purl.obolibrary.org/obo/BFO_0000015	process		2 ATP + 2 H(2)O + 2 L-glutamine + 1 hydrogenobyrinic acid => 2 ADP + 2 L-glutamate + 1 hydrogenobyrinic acid a,c-diamide + 2 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00221	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route): step 10/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 Co(2+) + 1 H(2)O + 1 hydrogenobyrinic acid a,c-diamide => 1 ADP + 1 H(+) + 1 cob(II)yrinate a,c-diamide + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00222	sirohydrochlorin from precorrin-2: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 precorrin-2 => 1 H(+) + 1 NADH + 1 sirohydrochlorin.
http://purl.obolibrary.org/obo/UPa_UER00223	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 1/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 Co(2+) + 1 sirohydrochlorin => 2 H(+) + 1 cobalt-precorrin-2.
http://purl.obolibrary.org/obo/UPa_UER00224	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 2/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 cobalt-precorrin-2 => 1 S-adenosyl-L-homocysteine + 1 cobalt-precorrin 3.
http://purl.obolibrary.org/obo/UPa_UER00225	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 3/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 cobalt-precorrin 3 => 1 S-adenosyl-L-homocysteine + 1 cobalt-precorrin 4.
http://purl.obolibrary.org/obo/UPa_UER00226	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 4/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 cobalt-precorrin 4 => 1 S-adenosyl-L-homocysteine + 1 cobalt-precorrin 5A.
http://purl.obolibrary.org/obo/UPa_UER00227	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 6/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 cobalt-precorrin 5B => 1 S-adenosyl-L-homocysteine + 1 cobalt-precorrin-6A.
http://purl.obolibrary.org/obo/UPa_UER00228	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 7/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 cobalt-precorrin-6A => 1 NAD(+) + 1 cobalt-precorrin-6B.
http://purl.obolibrary.org/obo/UPa_UER00229	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 8/10	http://purl.obolibrary.org/obo/BFO_0000015	process		2 S-adenosyl-L-methionine + 1 cobalt-precorrin-6B => 1 CO(2) + 2 S-adenosyl-L-homocysteine + 1 cobalt-precorrin 8.
http://purl.obolibrary.org/obo/UPa_UER00230	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 9/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 cobalt-precorrin 8 => 1 cob(III)yrinic acid.
http://purl.obolibrary.org/obo/UPa_UER00231	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 10/10	http://purl.obolibrary.org/obo/BFO_0000015	process		2 ATP + 2 H(2)O + 2 L-glutamine + 1 cob(III)yrinic acid => 2 ADP + 2 L-glutamate + 1 cob(II)yrinate a,c-diamide + 2 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00232	adenosylcobalamin from cob(II)yrinate a,c-diamide: step 1/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 FMNH(2) + 2 cob(II)yrinate a,c-diamide => 1 FMN + 2 H(+) + 2 cob(I)yrinic acid a,c-diamide.
http://purl.obolibrary.org/obo/UPa_UER00233	adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 cob(I)yrinic acid a,c-diamide => 1 adenosylcob(III)yrinic acid a,c-diamide + 1 triphosphate.
http://purl.obolibrary.org/obo/UPa_UER00234	adenosylcobalamin from cob(II)yrinate a,c-diamide: step 3/7	http://purl.obolibrary.org/obo/BFO_0000015	process		4 ATP + 4 H(2)O + 4 L-glutamine + 1 adenosylcob(III)yrinic acid a,c-diamide => 4 ADP + 4 L-glutamate + 1 adenosylcobyrinic acid a,c-diamide + 4 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00235	adenosylcobalamin from cob(II)yrinate a,c-diamide: step 4/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-1-aminopropan-2-ol + 1 adenosylcobyrinic acid a,c-diamide => 1 H(2)O + 1 adenosylcobinamide.
http://purl.obolibrary.org/obo/UPa_UER00236	adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7	http://purl.obolibrary.org/obo/BFO_0000015	process		adenosylcobinamide + [ATP or GTP] => adenosylcobinamide phosphate + [ADP or GDP].
http://purl.obolibrary.org/obo/UPa_UER00237	adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GTP + 1 adenosylcobinamide phosphate => 1 adenosylcobinamide-GDP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00238	adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 adenosylcobinamide-GDP + 1 alpha-ribazole => 1 GMP + 1 adenosylcobalamin.
http://purl.obolibrary.org/obo/UPa_UER00239	penicillin G from L-alpha-aminoadipate and L-cysteine and L-valine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		3 ATP + 1 H(2)O + 1 L-alpha-aminoadipate + 1 L-cysteine + 1 L-valine => 3 AMP + 1 N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00240	penicillin G from L-alpha-aminoadipate and L-cysteine and L-valine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 1 O(2) => 2 H(2)O + 1 isopenicillin N.
http://purl.obolibrary.org/obo/UPa_UER00241	penicillin G from L-alpha-aminoadipate and L-cysteine and L-valine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 isopenicillin N + 1 phenylacetyl-CoA => 1 CoA + 1 L-alpha-aminoadipate + 1 penicillin G.
http://purl.obolibrary.org/obo/UPa_UER00242	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 1/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glyceraldehyde 3-phosphate + 1 L-arginine => 1 N(2)-(2-carboxyethyl)-L-arginine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00243	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 2/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 N(2)-(2-carboxyethyl)-L-arginine => 1 AMP + 1 deoxyamidinoproclavaminic acid + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00244	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 3/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 O(2) + 1 deoxyamidinoproclavaminic acid => 1 CO(2) + 1 amidinoproclavaminic acid + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00245	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 4/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 amidinoproclavaminic acid => 1 proclavaminic acid + 1 urea.
http://purl.obolibrary.org/obo/UPa_UER00246	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 5/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 O(2) + 1 proclavaminic acid => 1 CO(2) + 1 H(2)O + 1 dihydroclavaminic acid + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00247	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 6/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 O(2) + 1 dihydroclavaminic acid => 1 CO(2) + 1 H(2)O + 1 clavaminate + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00248	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 7/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 clavaminate => 1 clavulanate-9-aldehyde.
http://purl.obolibrary.org/obo/UPa_UER00249	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine: step 8/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 clavulanate-9-aldehyde => 1 NADP(+) + 1 clavulanate.
http://purl.obolibrary.org/obo/UPa_UER00250	2-hydroxy-2,4-pentadienoate and benzoate from biphenyl: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 biphenyl => 1 NAD(+) + 1 cis-3-phenylcyclohexa-3,5-diene-1,2-diol.
http://purl.obolibrary.org/obo/UPa_UER00251	2-hydroxy-2,4-pentadienoate and benzoate from biphenyl: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 cis-3-phenylcyclohexa-3,5-diene-1,2-diol => 1 H(+) + 1 NADH + 1 biphenyl-2,3-diol.
http://purl.obolibrary.org/obo/UPa_UER00252	2-hydroxy-2,4-pentadienoate and benzoate from biphenyl: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 biphenyl-2,3-diol => 1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate.
http://purl.obolibrary.org/obo/UPa_UER00253	2-hydroxy-2,4-pentadienoate and benzoate from biphenyl: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + 1 H(2)O => 1 2-hydroxy-2,4-pentadienoate + 1 benzoate.
http://purl.obolibrary.org/obo/UPa_UER00254	catechol from benzoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 benzoate => 1 (1R,6S)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00255	catechol from benzoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (1R,6S)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid + 1 NAD(+) => 1 CO(2) + 1 H(+) + 1 NADH + 1 catechol.
http://purl.obolibrary.org/obo/UPa_UER00256	3,4-dihydroxybenzoate from benzoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 benzoate => 1 4-hydroxybenzoate + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00257	3,4-dihydroxybenzoate from benzoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-hydroxybenzoate + 1 H(+) + 1 NADPH + 1 O(2) => 1 3,4-dihydroxybenzoate + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00258	5-oxo-4,5-dihydro-2-furylacetate from catechol: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 catechol => 1 cis,cis-muconate.
http://purl.obolibrary.org/obo/UPa_UER00259	5-oxo-4,5-dihydro-2-furylacetate from catechol: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 cis,cis-muconate => 1 (S)-5-oxo-2,5-dihydro-2-furylacetic acid.
http://purl.obolibrary.org/obo/UPa_UER00260	5-oxo-4,5-dihydro-2-furylacetate from catechol: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-5-oxo-2,5-dihydro-2-furylacetic acid => 1 5-oxo-4,5-dihydro-2-furylacetate.
http://purl.obolibrary.org/obo/UPa_UER00261	3-oxoadipate from 5-oxo-4,5-dihydro-2-furylacetate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-oxo-4,5-dihydro-2-furylacetate + 1 H(2)O => 1 3-oxoadipate.
http://purl.obolibrary.org/obo/UPa_UER00262	acetyl-CoA and succinyl-CoA from 3-oxoadipate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-oxoadipate + 1 succinyl-CoA => 1 3-oxoadipyl-CoA + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00263	acetyl-CoA and succinyl-CoA from 3-oxoadipate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-oxoadipyl-CoA + 1 CoA => 1 acetyl-CoA + 1 succinyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00264	3-carboxy-cis,cis-muconate from 3,4-dihydroxybenzoate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3,4-dihydroxybenzoate + 1 O(2) => 1 3-carboxy-cis,cis-muconate.
http://purl.obolibrary.org/obo/UPa_UER00265	5-oxo-4,5-dihydro-2-furylacetate from 3-carboxy-cis,cis-muconate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-carboxy-cis,cis-muconate => 1 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate.
http://purl.obolibrary.org/obo/UPa_UER00266	5-oxo-4,5-dihydro-2-furylacetate from 3-carboxy-cis,cis-muconate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-carboxy-2,5-dihydro-5-oxofuran-2-acetate => 1 5-oxo-4,5-dihydro-2-furylacetate + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00267	3-oxoadipate from 3,4-dihydroxybenzoate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		3,4-dihydroxybenzoate + H(+) + O(2) + [NADH or NADPH] => CO(2) + H(2)O + benzene-1,2,4-triol + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00268	3-oxoadipate from 3,4-dihydroxybenzoate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 benzene-1,2,4-triol => 1 3-hydroxy-cis,cis-muconate.
http://purl.obolibrary.org/obo/UPa_UER00269	3-oxoadipate from 3,4-dihydroxybenzoate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-hydroxy-cis,cis-muconate => 1 maleylacetate.
http://purl.obolibrary.org/obo/UPa_UER00270	L-ornithine and urea from L-arginine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-arginine => 1 L-ornithine + 1 urea.
http://purl.obolibrary.org/obo/UPa_UER00271	L-citrulline from L-ornithine and carbamoyl phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-ornithine + 1 carbamoyl phosphate => 1 L-citrulline + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00272	(N(omega)-L-arginino)succinate from L-aspartate and L-citrulline: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-aspartate + 1 L-citrulline => 1 (N(omega)-L-arginino)succinate + 1 AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00273	L-arginine and fumarate from (N(omega)-L-arginino)succinate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (N(omega)-L-arginino)succinate => 1 L-arginine + 1 fumarate.
http://purl.obolibrary.org/obo/UPa_UER00274	UDP from UMP (UMK/CMK route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 UMP => 1 ADP + 1 UDP.
http://purl.obolibrary.org/obo/UPa_UER00275	UDP from UMP (UMPK route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 UMP => 1 ADP + 1 UDP.
http://purl.obolibrary.org/obo/UPa_UER00276	CTP from UDP: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 UDP => 1 ADP + 1 UTP.
http://purl.obolibrary.org/obo/UPa_UER00277	CTP from UDP: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 NH(3) + 1 UTP => 1 ADP + 1 CTP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00278	3-oxoadipate from 3,4-dihydroxybenzoate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		H(+) + maleylacetate + [NADH or NADPH] => 3-oxoadipate + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00279	L-glutamate and succinate from L-arginine: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arginine + 1 succinyl-CoA => 1 CoA + 1 N(2)-succinyl-L-arginine.
http://purl.obolibrary.org/obo/UPa_UER00280	L-glutamate and succinate from L-arginine: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(2)O + 1 N(2)-succinyl-L-arginine => 1 CO(2) + 1 N(2)-succinyl-L-ornithine + 2 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00281	L-glutamate and succinate from L-arginine: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 N(2)-succinyl-L-ornithine => 1 L-glutamate + 1 N-succinyl-L-glutamate 5-semialdehyde.
http://purl.obolibrary.org/obo/UPa_UER00282	L-glutamate and succinate from L-arginine: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-succinyl-L-glutamate 5-semialdehyde + 1 NAD(+) => 1 H(+) + 1 N(2)-succinyl-L-glutamic acid + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00283	L-glutamate and succinate from L-arginine: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N(2)-succinyl-L-glutamic acid => 1 L-glutamate + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00284	agmatine from L-arginine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arginine => 1 CO(2) + 1 agmatine.
http://purl.obolibrary.org/obo/UPa_UER00285	N-carbamoylputrescine from agmatine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 agmatine => 1 N-carbamoylputrescine + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00286	putrescine from N-carbamoylputrescine (amidase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-carbamoylputrescine => 1 CO(2) + 1 NH(3) + 1 putrescine.
http://purl.obolibrary.org/obo/UPa_UER00287	putrescine from agmatine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 agmatine => 1 putrescine + 1 urea.
http://purl.obolibrary.org/obo/UPa_UER00288	putrescine from L-ornithine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-ornithine => 1 CO(2) + 1 putrescine.
http://purl.obolibrary.org/obo/UPa_UER00289	4-aminobutanal from putrescine (amine oxidase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O(2) + 1 putrescine => 1 4-aminobutanal + 1 H(2)O(2) + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00290	4-aminobutanal from putrescine (transaminase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 putrescine => 1 4-aminobutanal + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00291	1,3-diaminopropane and 4-aminobutanal from spermidine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acceptor + 1 spermidine => 1 1,3-diaminopropane + 1 4-aminobutanal + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00292	4-aminobutanoate from 4-aminobutanal: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-aminobutanal + 1 H(2)O + 1 NAD(+) => 1 4-aminobutanoate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00293	succinate semialdehyde from 4-aminobutanoate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 4-aminobutanoate => 1 L-glutamate + 1 succinate semialdehyde.
http://purl.obolibrary.org/obo/UPa_UER00295	XMP from IMP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 IMP + 1 NAD(+) => 1 H(+) + 1 NADH + 1 XMP.
http://purl.obolibrary.org/obo/UPa_UER00296	GMP from XMP (L-Gln route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 H(2)O + 1 L-glutamine + 1 XMP => 1 AMP + 1 GMP + 1 L-glutamate + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00297	GMP from XMP (ammonia route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 NH(3) + 1 XMP => 1 AMP + 1 GMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00298	pyridoxal 5'-phosphate from pyridoxal: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 pyridoxal => 1 ADP + 1 pyridoxal 5'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00299	pyridoxamine 5'-phosphate from pyridoxamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 pyridoxamine => 1 ADP + 1 pyridoxamine 5'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00300	pyridoxine 5'-phosphate from pyridoxine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 pyridoxine => 1 ADP + 1 pyridoxine 5'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00301	pyridoxal from pyridoxal 5'-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 pyridoxal 5'-phosphate => 1 phosphate + 1 pyridoxal.
http://purl.obolibrary.org/obo/UPa_UER00302	pyridoxamine from pyridoxamine 5'-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 pyridoxamine 5'-phosphate => 1 phosphate + 1 pyridoxamine.
http://purl.obolibrary.org/obo/UPa_UER00303	pyridoxine from pyridoxine 5'-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 pyridoxine 5'-phosphate => 1 phosphate + 1 pyridoxine.
http://purl.obolibrary.org/obo/UPa_UER00304	pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O(2) + 1 pyridoxamine 5'-phosphate => 1 H(2)O(2) + 1 NH(3) + 1 pyridoxal 5'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00305	pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 pyridoxine 5'-phosphate => 1 H(2)O(2) + 1 pyridoxal 5'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00306	pyridoxal from pyridoxamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 pyridoxamine + 1 pyruvate => 1 L-alanine + 1 pyridoxal.
http://purl.obolibrary.org/obo/UPa_UER00307	pyridoxal from pyridoxine (dehydrogenase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NADP(+) + 1 pyridoxine => 1 H(+) + 1 NADPH + 1 pyridoxal.
http://purl.obolibrary.org/obo/UPa_UER00308	3-carboxy-cis,cis-muconate from 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate => 1 3-carboxy-cis,cis-muconate.
http://purl.obolibrary.org/obo/UPa_UER00309	pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-erythrose 4-phosphate + 1 H(2)O + 1 NAD(+) => 1 4-phospho-D-erythronate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00310	pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-phospho-D-erythronate + 1 NAD(+) => 1 (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00311	pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid + 1 L-glutamate => 1 2-oxoglutarate + 1 4-(phosphonooxy)-L-threonine.
http://purl.obolibrary.org/obo/UPa_UER00312	pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-(phosphonooxy)-L-threonine + 1 NAD(+) => 1 3-amino-2-oxopropyl phosphate + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00313	pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-deoxy-D-xylulose 5-phosphate + 1 3-amino-2-oxopropyl phosphate => 2 H(2)O + 1 phosphate + 1 pyridoxine 5'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00314	spermidine from putrescine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosylmethioninamine + 1 putrescine => 1 S-methyl-5'-thioadenosine + 1 spermidine.
http://purl.obolibrary.org/obo/UPa_UER00315	spermine from spermidine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosylmethioninamine + 1 spermidine => 1 S-methyl-5'-thioadenosine + 1 spermine.
http://purl.obolibrary.org/obo/UPa_UER00316	5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-glutamyl-tRNA(Glu) + 1 NADPH => 1 (S)-4-amino-5-oxopentanoic acid + 1 NADP(+) + 1 tRNA(Glu).
http://purl.obolibrary.org/obo/UPa_UER00317	5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-4-amino-5-oxopentanoic acid => 1 5-aminolevulinate.
http://purl.obolibrary.org/obo/UPa_UER00318	coproporphyrinogen-III from 5-aminolevulinate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		2 5-aminolevulinate => 2 H(2)O + 1 porphobilinogen.
http://purl.obolibrary.org/obo/UPa_UER00319	coproporphyrinogen-III from 5-aminolevulinate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 4 porphobilinogen => 4 NH(3) + 1 hydroxymethylbilane.
http://purl.obolibrary.org/obo/UPa_UER00320	coproporphyrinogen-III from 5-aminolevulinate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 hydroxymethylbilane => 1 H(2)O + 1 uroporphyrinogen III.
http://purl.obolibrary.org/obo/UPa_UER00321	coproporphyrinogen-III from 5-aminolevulinate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 uroporphyrinogen III => 4 CO(2) + 1 coproporphyrinogen-III.
http://purl.obolibrary.org/obo/UPa_UER00322	protoporphyrinogen-IX from coproporphyrinogen-III (O2 route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 coproporphyrinogen-III => 2 CO(2) + 2 H(2)O + 1 protoporphyrinogen-IX.
http://purl.obolibrary.org/obo/UPa_UER00323	protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 S-adenosyl-L-methionine + 1 coproporphyrinogen-III => 2 5'-deoxyadenosine + 2 CO(2) + 2 L-methionine + 1 protoporphyrinogen-IX.
http://purl.obolibrary.org/obo/UPa_UER00324	protoporphyrin-IX from protoporphyrinogen-IX: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		3 O(2) + 1 protoporphyrinogen-IX => 3 H(2)O(2) + 1 protoporphyrin-IX.
http://purl.obolibrary.org/obo/UPa_UER00325	protoheme from protoporphyrin-IX: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 Fe2+ + 1 protoporphyrin-IX => 2 H(+) + 1 protoheme.
http://purl.obolibrary.org/obo/UPa_UER00326	iminoaspartate from L-aspartate (oxidase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate + 1 O(2) => 1 H(2)O(2) + 1 iminoaspartate.
http://purl.obolibrary.org/obo/UPa_UER00327	quinolinate from iminoaspartate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 glycerone phosphate + 1 iminoaspartate => 2 H(2)O + 1 phosphate + 1 quinolinate.
http://purl.obolibrary.org/obo/UPa_UER00328	quinolinate from L-kynurenine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-kynurenine + 1 NADPH + 1 O(2) => 1 3-hydroxy-L-kynurenine + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00329	quinolinate from L-kynurenine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-hydroxy-L-kynurenine + 1 H(2)O => 1 3-hydroxyanthranilate + 1 L-alanine.
http://purl.obolibrary.org/obo/UPa_UER00330	quinolinate from L-kynurenine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-hydroxyanthranilate + 1 O(2) => 1 H(2)O + 1 quinolinate.
http://purl.obolibrary.org/obo/UPa_UER00331	nicotinate D-ribonucleotide from quinolinate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 quinolinate => 1 CO(2) + 1 diphosphate + 1 nicotinate D-ribonucleotide.
http://purl.obolibrary.org/obo/UPa_UER00332	deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 nicotinate D-ribonucleotide => 1 deamido-NAD(+) + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00333	NAD(+) from deamido-NAD(+) (ammonia route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 NH(3) + 1 deamido-NAD(+) => 1 AMP + 1 NAD(+) + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00334	NAD(+) from deamido-NAD(+) (L-Gln route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 H(2)O + 1 L-glutamine + 1 deamido-NAD(+) => 1 AMP + 1 L-glutamate + 1 NAD(+) + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00335	AMP from IMP: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GTP + 1 IMP + 1 L-aspartate => 1 GDP + 1 N(6)-(1,2-dicarboxyethyl)-AMP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00336	AMP from IMP: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N(6)-(1,2-dicarboxyethyl)-AMP => 1 AMP + 1 fumarate.
http://purl.obolibrary.org/obo/UPa_UER00337	acetoacetate and fumarate from L-phenylalanine: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-phenylalanine + 1 O(2) + 1 tetrahydrobiopterin => 1 4a-hydroxytetrahydrobiopterin + 1 L-tyrosine.
http://purl.obolibrary.org/obo/UPa_UER00338	acetoacetate and fumarate from L-phenylalanine: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 L-tyrosine => 1 (4-hydroxyphenyl)pyruvate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00339	acetoacetate and fumarate from L-phenylalanine: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 homogentisate => 1 4-maleylacetoacetate.
http://purl.obolibrary.org/obo/UPa_UER00340	acetoacetate and fumarate from L-phenylalanine: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-maleylacetoacetate => 1 4-fumarylacetoacetate.
http://purl.obolibrary.org/obo/UPa_UER00341	acetoacetate and fumarate from L-phenylalanine: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-fumarylacetoacetate + 1 H(2)O => 1 acetoacetate + 1 fumarate.
http://purl.obolibrary.org/obo/UPa_UER00342	L-arogenate from prephenate (L-Asp route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate + 1 prephenate => 1 L-arogenate + 1 oxaloacetate.
http://purl.obolibrary.org/obo/UPa_UER00343	L-arogenate from prephenate (L-Glu route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 prephenate => 1 2-oxoglutarate + 1 L-arogenate.
http://purl.obolibrary.org/obo/UPa_UER00344	L-phenylalanine from L-arogenate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arogenate => 1 CO(2) + 1 H(2)O + 1 L-phenylalanine.
http://purl.obolibrary.org/obo/UPa_UER00345	phenylpyruvate from prephenate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 prephenate => 1 CO(2) + 1 H(2)O + 1 phenylpyruvate.
http://purl.obolibrary.org/obo/UPa_UER00346	L-phenylalanine from phenylpyruvate (PDH route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 NH(3) + 1 phenylpyruvate => 1 H(2)O + 1 L-phenylalanine + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00347	L-phenylalanine from phenylpyruvate (ArAT route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 phenylpyruvate => 1 2-oxoglutarate + 1 L-phenylalanine.
http://purl.obolibrary.org/obo/UPa_UER00350	L-tyrosine from (4-hydroxyphenyl)pyruvate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (4-hydroxyphenyl)pyruvate + 1 L-glutamate => 1 2-oxoglutarate + 1 L-tyrosine.
http://purl.obolibrary.org/obo/UPa_UER00351	pimeloyl-CoA from pimelate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 CoA + 1 pimelate => 1 AMP + 1 diphosphate + 1 pimeloyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00352	CoA from (R)-pantothenate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-pantothenate + 1 ATP => 1 (R)-4'-phosphopantothenate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00353	CoA from (R)-pantothenate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-4'-phosphopantothenate + 1 CTP + 1 L-cysteine => 1 CMP + 1 N-[(R)-4-phosphonopantothenoyl]-L-cysteine + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00354	CoA from (R)-pantothenate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-[(R)-4-phosphonopantothenoyl]-L-cysteine => 1 CO(2) + 1 pantotheine 4'-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00355	CoA from (R)-pantothenate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 pantotheine 4'-phosphate => 1 3'-dephospho-CoA + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00356	CoA from (R)-pantothenate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3'-dephospho-CoA + 1 ATP => 1 ADP + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00357	L-proline from L-ornithine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-ornithine => 1 L-proline + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00358	L-glutamate 5-semialdehyde from L-ornithine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 L-ornithine => 1 L-glutamate + 1 L-glutamate 5-semialdehyde.
http://purl.obolibrary.org/obo/UPa_UER00359	L-glutamate 5-semialdehyde from L-glutamate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-glutamate => 1 ADP + 1 L-glutamyl 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00360	L-glutamate 5-semialdehyde from L-glutamate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-glutamyl 5-phosphate + 1 NADPH => 1 L-glutamate 5-semialdehyde + 1 NADP(+) + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00361	L-proline from L-glutamate 5-semialdehyde: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-glutamate 5-semialdehyde + 1 NADH => 1 H(2)O + 1 L-proline + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00362	acetoacetate and fumarate from L-phenylalanine: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (4-hydroxyphenyl)pyruvate + 1 O(2) => 1 CO(2) + 1 homogentisate.
http://purl.obolibrary.org/obo/UPa_UER00363	N-acetylputrescine from putrescine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetyl-CoA + 1 putrescine => 1 CoA + 1 N-acetylputrescine.
http://purl.obolibrary.org/obo/UPa_UER00364	carbamoyl phosphate from L-arginine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-arginine => 1 L-citrulline + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00365	carbamoyl phosphate from L-arginine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-citrulline + 1 phosphate => 1 L-ornithine + 1 carbamoyl phosphate.
http://purl.obolibrary.org/obo/UPa_UER00366	CO(2) and NH(3) from carbamoyl phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ADP + 1 carbamoyl phosphate => 1 ATP + 1 CO(2) + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00367	(S)-3-hydroxy-3-methylglutaryl-CoA from (R)-mevalonate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-mevalonate + 1 CoA + 2 NAD(+) => 1 (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH.
http://purl.obolibrary.org/obo/UPa_UER00368	geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 dimethylallyl diphosphate + 1 isopentenyl diphosphate => 1 diphosphate + 1 geranyl diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00369	farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 geranyl diphosphate + 1 isopentenyl diphosphate => 1 diphosphate + 1 farnesyl diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00370	CO(2) and NH(3) from urea (urease route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 urea => 1 CO(2) + 2 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00371	CO(2) and NH(3) from urea (allophanate route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 bicarbonate + 1 urea => 1 ADP + 1 phosphate + 1 urea-1-carboxylate.
http://purl.obolibrary.org/obo/UPa_UER00372	CO(2) and NH(3) from urea (allophanate route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 urea-1-carboxylate => 2 CO(2) + 2 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00373	L-glutamate from L-proline: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-proline + 1 Quinone => 1 (S)-1-pyrroline-5-carboxylic acid + 1 Hydroquinone.
http://purl.obolibrary.org/obo/UPa_UER00374	L-glutamate from L-proline: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-1-pyrroline-5-carboxylic acid + 2 H(2)O + 1 NAD(+) => 1 H(+) + 1 L-glutamate + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00375	5-aminolevulinate from glycine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 glycine + 1 succinyl-CoA => 1 5-aminolevulinate + 1 CO(2) + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00376	siroheme from sirohydrochlorin: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 Fe2+ + 1 sirohydrochlorin => 2 H(+) + 1 siroheme.
http://purl.obolibrary.org/obo/UPa_UER00377	D-xylulose 5-phosphate from L-ascorbate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-ascorbate + 1 protein N(pi)-phospho-L-histidine => 1 3-dehydro-L-gulonate 6-phosphate + 1 protein-L-histidine.
http://purl.obolibrary.org/obo/UPa_UER00378	D-xylulose 5-phosphate from L-ascorbate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-dehydro-L-gulonate 6-phosphate + 1 H(+) => 1 CO(2) + 1 L-xylulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00379	D-xylulose 5-phosphate from L-ascorbate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-xylulose 5-phosphate => 1 L-ribulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00380	D-xylulose 5-phosphate from L-ascorbate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-ribulose 5-phosphate => 1 D-xylulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00381	betaine from glycine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 glycine => 1 S-adenosyl-L-homocysteine + 1 sarcosine.
http://purl.obolibrary.org/obo/UPa_UER00382	betaine from glycine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 sarcosine => 1 N,N-dimethylglycine + 1 S-adenosyl-L-homocysteine.
http://purl.obolibrary.org/obo/UPa_UER00383	betaine from glycine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N,N-dimethylglycine + 1 S-adenosyl-L-methionine => 1 S-adenosyl-L-homocysteine + 1 betaine.
http://purl.obolibrary.org/obo/UPa_UER00384	betaine from choline: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O(2) + 1 choline => 1 H(2)O(2) + 1 betaine.
http://purl.obolibrary.org/obo/UPa_UER00385	betaine aldehyde from choline (cytochrome c reductase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acceptor + 1 choline => 1 betaine aldehyde + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00386	betaine from betaine aldehyde: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 betaine aldehyde => 2 H(+) + 1 NADH + 1 betaine.
http://purl.obolibrary.org/obo/UPa_UER00387	glycolate from 1,2-dichloroethane: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,2-dichloroethane + 1 H(2)O => 1 2-chloroethanol + 1 HCl.
http://purl.obolibrary.org/obo/UPa_UER00388	glycolate from 1,2-dichloroethane: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-chloroethanol + 2 ferricytochrome c => 2 H(+) + 1 chloroacetaldehyde + 2 ferrocytochrome c.
http://purl.obolibrary.org/obo/UPa_UER00389	glycolate from 1,2-dichloroethane: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 chloroacetaldehyde => 1 H(+) + 1 NADH + 1 chloroacetic acid.
http://purl.obolibrary.org/obo/UPa_UER00390	glycolate from 1,2-dichloroethane: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 chloroacetic acid => 1 HCl + 1 glycolate.
http://purl.obolibrary.org/obo/UPa_UER00391	catechol from benzene: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 benzene => 1 NAD(+) + 1 cis-1,2-dihydrobenzene-1,2-diol.
http://purl.obolibrary.org/obo/UPa_UER00392	catechol from benzene: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 cis-1,2-dihydrobenzene-1,2-diol => 1 H(+) + 1 NADH + 1 catechol.
http://purl.obolibrary.org/obo/UPa_UER00393	3-methylcatechol from toluene: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 toluene => 1 (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00394	3-methylcatechol from toluene: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + 1 NAD(+) => 1 3-methylcatechol + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00395	sarcosine from creatinine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 creatinine => 1 N-methylhydantoin + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00396	sarcosine from creatinine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 2 H(2)O + 1 N-methylhydantoin => 1 ADP + 1 N-carbamoylsarcosine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00397	sarcosine from creatinine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-carbamoylsarcosine => 1 CO(2) + 1 NH(3) + 1 sarcosine.
http://purl.obolibrary.org/obo/UPa_UER00398	formaldehyde and glycine from sarcosine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 electron-transferring flavoprotein + 1 sarcosine => 1 formaldehyde + 1 glycine + 1 reduced electron-transferring flavoprotein.
http://purl.obolibrary.org/obo/UPa_UER00399	2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-ribulose 5-phosphate => 1 2-hydroxy-3-oxobutyl phosphate + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00400	5-amino-6-(D-ribitylamino)uracil from GTP: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GTP + 3 H(2)O => 1 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + 1 diphosphate + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00401	5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine + 1 H(2)O => 1 5-amino-6-(5-phosphoribosylamino)uracil + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00402	5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-amino-6-(5-phosphoribosylamino)uracil + 1 H(+) + 1 NADPH => 1 5-amino-6-(5-phosphoribitylamino)uracil + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00403	5-amino-6-(D-ribitylamino)uracil from GTP: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-amino-6-(5-phosphoribitylamino)uracil + 1 H(2)O => 1 5-amino-6-(D-ribitylamino)uracil + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00404	riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-3-oxobutyl phosphate + 1 5-amino-6-(D-ribitylamino)uracil => 1 6,7-dimethyl-8-(1-D-ribityl)lumazine + 2 H(2)O + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00405	riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		2 6,7-dimethyl-8-(1-D-ribityl)lumazine => 1 5-amino-6-(D-ribitylamino)uracil + 1 riboflavin.
http://purl.obolibrary.org/obo/UPa_UER00406	FMN from riboflavin (ATP route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 riboflavin => 1 ADP + 1 FMN.
http://purl.obolibrary.org/obo/UPa_UER00407	FAD from FMN: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 FMN => 1 FAD + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00408	D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucose 6-phosphate + 1 NADP(+) => 1 D-glucono-1,5-lactone 6-phosphate + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00409	D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucono-1,5-lactone 6-phosphate + 1 H(2)O => 1 6-phospho-D-gluconate.
http://purl.obolibrary.org/obo/UPa_UER00410	D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-phospho-D-gluconate + 1 NADP(+) => 1 CO(2) + 1 D-ribulose 5-phosphate + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00411	D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-ribulose 5-phosphate => 1 D-xylulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00412	D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-ribulose 5-phosphate => 1 D-ribose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00413	D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-ribose 5-phosphate + 1 D-xylulose 5-phosphate => 1 D-glyceraldehyde 3-phosphate + 1 sedoheptulose 7-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00414	D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glyceraldehyde 3-phosphate + 1 sedoheptulose 7-phosphate => 1 D-erythrose 4-phosphate + 1 beta-D-fructose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00415	D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-erythrose 4-phosphate + 1 D-xylulose 5-phosphate => 1 D-glyceraldehyde 3-phosphate + 1 beta-D-fructose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00416	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate: step 1/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-hydroxyphenylacetate + 1 H(+) + 1 NADH + 1 O(2) => 1 (3,4-dihydroxyphenyl)acetate + 1 H(2)O + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00417	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate: step 2/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (3,4-dihydroxyphenyl)acetate + 1 O(2) => 1 5-carboxymethyl-2-hydroxymuconate semialdehyde.
http://purl.obolibrary.org/obo/UPa_UER00418	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate: step 3/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-carboxymethyl-2-hydroxymuconate semialdehyde + 1 H(2)O + 1 NAD(+) => 1 5-carboxymethyl-2-hydroxymuconic acid + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00419	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate: step 4/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-carboxymethyl-2-hydroxymuconic acid => 1 5-oxopent-3-ene-1,2,5-tricarboxylic acid.
http://purl.obolibrary.org/obo/UPa_UER00420	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate: step 5/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-oxopent-3-ene-1,2,5-tricarboxylic acid => 1 2-hydroxy-hept-2,4-diene-1,7-dioic acid + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00421	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate: step 6/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-hept-2,4-diene-1,7-dioic acid + 1 H(2)O => 1 2,4-dihydroxyhept-2-enedioic acid.
http://purl.obolibrary.org/obo/UPa_UER00422	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate: step 7/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,4-dihydroxyhept-2-enedioic acid => 1 pyruvate + 1 succinate semialdehyde.
http://purl.obolibrary.org/obo/UPa_UER00423	alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-fructose 6-phosphate => 1 D-mannose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00424	alpha-D-mannose 1-phosphate from D-fructose 6-phosphate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-mannose 6-phosphate => 1 alpha-D-mannose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00425	GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GDP route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GDP + 1 alpha-D-mannose 1-phosphate => 1 GDP-alpha-D-mannose + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00427	glycine from L-allo-threonine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-allo-threonine => 1 acetaldehyde + 1 glycine.
http://purl.obolibrary.org/obo/UPa_UER00428	glycine from glyoxylate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-alanine + 1 glyoxylate => 1 glycine + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00429	acetaldehyde and glycine from L-threonine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-threonine => 1 acetaldehyde + 1 glycine.
http://purl.obolibrary.org/obo/UPa_UER00430	betaine aldehyde from choline (monooxygenase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(+) + 1 O(2) + 1 choline + 2 reduced ferredoxin => 2 H(2)O + 1 betaine aldehyde + 2 oxidized ferredoxin.
http://purl.obolibrary.org/obo/UPa_UER00431	choline from choline sulfate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 choline sulfate => 1 choline + 1 sulfate.
http://purl.obolibrary.org/obo/UPa_UER00432	sarcosine from betaine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-homocysteine + 1 betaine => 1 L-methionine + 1 N,N-dimethylglycine.
http://purl.obolibrary.org/obo/UPa_UER00433	sarcosine from betaine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N,N-dimethylglycine + 1 electron-transferring flavoprotein => 1 formaldehyde + 1 reduced electron-transferring flavoprotein + 1 sarcosine.
http://purl.obolibrary.org/obo/UPa_UER00434	D-fructose 6-phosphate from D-ribulose 5-phosphate and formaldehyde: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-ribulose 5-phosphate + 1 formaldehyde => 1 D-arabino-3-hexulose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00435	D-fructose 6-phosphate from D-ribulose 5-phosphate and formaldehyde: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-arabino-3-hexulose 6-phosphate => 1 D-fructose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00436	D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 sedoheptulose 7-phosphate => 1 D-glycero-alpha-D-manno-heptose 7-phosphate + 1 D-glycero-beta-D-manno-heptose 7-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00437	ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-glycero-beta-D-manno-heptose 7-phosphate => 1 ADP + 1 D-glycero-beta-D-manno-heptose 1,7-diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00438	ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glycero-beta-D-manno-heptose 1,7-diphosphate + 1 H(2)O => 1 D-glycero-beta-D-manno-heptose 1-phosphate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00439	ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-glycero-beta-D-manno-heptose 1-phosphate => 1 ADP-D-glycero-beta-D-manno-heptose + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00440	ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ADP-D-glycero-beta-D-manno-heptose => 1 ADP-L-glycero-beta-D-manno-heptose.
http://purl.obolibrary.org/obo/UPa_UER00441	(S)-reticuline from (S)-norcoclaurine: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-norcoclaurine + 1 S-adenosyl-L-methionine => 1 (S)-coclaurine + 1 S-adenosyl-L-homocysteine.
http://purl.obolibrary.org/obo/UPa_UER00442	(S)-reticuline from (S)-norcoclaurine: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-coclaurine + 1 S-adenosyl-L-methionine => 1 (S)-N-methylcoclaurine + 1 H(+) + 1 S-adenosyl-L-homocysteine.
http://purl.obolibrary.org/obo/UPa_UER00443	(S)-reticuline from (S)-norcoclaurine: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-N-methylcoclaurine + 1 H(+) + 1 NADPH + 1 O(2) => 1 (S)-3'-hydroxy-N-methylcoclaurine + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00444	(S)-reticuline from (S)-norcoclaurine: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-3'-hydroxy-N-methylcoclaurine + 1 S-adenosyl-L-methionine => 1 (S)-reticuline + 1 H(+) + 1 S-adenosyl-L-homocysteine.
http://purl.obolibrary.org/obo/UPa_UER00445	palmatine from columbamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 columbamine => 1 S-adenosyl-L-homocysteine + 1 palmatine.
http://purl.obolibrary.org/obo/UPa_UER00446	berbamunine from (R)-N-methylcoclaurine and (S)-N-methylcoclaurine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-N-methylcoclaurine + 1 (S)-N-methylcoclaurine + 1 H(+) + 1 NADPH + 1 O(2) => 2 H(2)O + 1 NADP(+) + 1 berbamunine.
http://purl.obolibrary.org/obo/UPa_UER00447	3alpha(S)-strictosidine from secologanin and tryptamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 secologanin + 1 tryptamine => 1 3alpha(S)-strictosidine + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00448	L-cystathionine from O-acetyl-L-homoserine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-cysteine + 1 O-acetyl-L-homoserine => 1 L-cystathionine + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00449	L-homocysteine from O-succinyl-L-homoserine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O-succinyl-L-homoserine + 1 hydrogen sulfide => 1 L-homocysteine + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00450	(S)-scoulerine from (S)-reticuline: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-reticuline + 1 O(2) => 1 (S)-scoulerine + 1 H(2)O(2).
http://purl.obolibrary.org/obo/UPa_UER00451	S-adenosylmethioninamine from S-adenosyl-L-methionine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 S-adenosyl-L-methionine => 1 CO(2) + 1 S-adenosylmethioninamine.
http://purl.obolibrary.org/obo/UPa_UER00452	indole and pyruvate from L-tryptophan: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-tryptophan => 1 NH(3) + 1 indole + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00453	L-kynurenine from L-tryptophan: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-tryptophan + 1 O(2) => 1 N-formyl-N-kynurenine.
http://purl.obolibrary.org/obo/UPa_UER00454	L-kynurenine from L-tryptophan: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-formyl-N-kynurenine => 1 L-kynurenine + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00455	L-alanine and anthranilate from L-kynurenine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-kynurenine => 1 L-alanine + 1 anthranilate.
http://purl.obolibrary.org/obo/UPa_UER00456	iminoaspartate from L-aspartate (dehydrogenase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		L-aspartate + [NAD(+) or NADP(+)] => H(+) + iminoaspartate + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00457	nicotinate D-ribonucleotide from nicotinate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 ATP + 1 H(+) + 1 H(2)O + 1 nicotinate => 1 ADP + 1 diphosphate + 1 nicotinate D-ribonucleotide + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00458	acetyl-CoA from acetate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 acetate => 1 ADP + 1 acetyl phosphate.
http://purl.obolibrary.org/obo/UPa_UER00459	acetyl-CoA from acetate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CoA + 1 acetyl phosphate => 1 acetyl-CoA + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00461	L-threonine from L-aspartate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-aspartate => 1 4-phospho-L-aspartate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00462	L-homoserine from L-aspartate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-aspartate => 1 4-phospho-L-aspartate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00463	L-threonine from L-aspartate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-phospho-L-aspartate + 1 H(+) + 1 NADPH => 1 L-aspartate 4-semialdehyde + 1 NADP(+) + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00464	L-homoserine from L-aspartate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-phospho-L-aspartate + 1 H(+) + 1 NADPH => 1 L-aspartate 4-semialdehyde + 1 NADP(+) + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00465	L-homoserine from L-aspartate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		H(+) + L-aspartate 4-semialdehyde + [NADH or NADPH] => L-homoserine + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00466	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (aminotransferase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-tetrahydrodipicolinate + 1 H(2)O + 1 L-glutamate => 1 2-oxoglutarate + 1 LL-2,6-diaminopimelate.
http://purl.obolibrary.org/obo/UPa_UER00467	D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-deoxy-alpha-D-ribose 1-phosphate => 1 2-deoxy-D-ribose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00468	D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-deoxy-D-ribose 5-phosphate => 1 D-glyceraldehyde 3-phosphate + 1 acetaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00469	sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 phosphoenolpyruvate + 1 sulfite => 1 (2R)-O-phospho-3-sulfolactic acid.
http://purl.obolibrary.org/obo/UPa_UER00470	sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2R)-O-phospho-3-sulfolactic acid + 1 H(2)O => 1 (R)-3-sulfolactate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00471	sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-3-sulfolactate + 1 NAD(+) => 1 3-sulfopyruvate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00472	sulfoacetaldehyde from phosphoenolpyruvate and sulfite: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-sulfopyruvate => 1 CO(2) + 1 sulfoacetaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00473	3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-ribulose 5-phosphate => 1 D-arabinose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00474	3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-arabinose 5-phosphate + 1 H(2)O + 1 phosphoenolpyruvate => 1 8-phospho-3-deoxy-D-manno-octulosonate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00475	3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 8-phospho-3-deoxy-D-manno-octulosonate + 1 H(2)O => 1 3-deoxy-D-manno-octulosonate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00476	CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-deoxy-D-manno-octulosonate + 1 CTP => 1 CMP-3-deoxy-D-manno-octulosonate + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00477	lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + 1 UDP-N-acetyl-alpha-D-glucosamine => 1 UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine + 1 acyl-carrier protein.
http://purl.obolibrary.org/obo/UPa_UER00478	lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine => 1 UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00479	lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] + 1 UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine => 1 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + 1 acyl-carrier protein.
http://purl.obolibrary.org/obo/UPa_UER00480	lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine => 1 UMP + 1 lipid X.
http://purl.obolibrary.org/obo/UPa_UER00481	lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine + 1 lipid X => 1 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + 1 UDP.
http://purl.obolibrary.org/obo/UPa_UER00482	lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate + 1 ATP => 1 ADP + 1 lipid IV(A).
http://purl.obolibrary.org/obo/UPa_UER00483	KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CMP-3-deoxy-D-manno-octulosonate + 1 lipid IV(A) => 1 3-deoxy-D-manno-octulosonyl-lipid IV((A)) + 1 CMP.
http://purl.obolibrary.org/obo/UPa_UER00484	KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-deoxy-D-manno-octulosonyl-lipid IV((A)) + 1 CMP-3-deoxy-D-manno-octulosonate => 1 CMP + 1 di[3-deoxy-D-manno-octulosonyl]-lipid IV(A).
http://purl.obolibrary.org/obo/UPa_UER00485	KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + 1 dodecanoyl-[acyl-carrier protein] => 1 acyl-carrier protein + 1 lauroyl-KDO(2)-lipid IV(A).
http://purl.obolibrary.org/obo/UPa_UER00486	KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A): step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 lauroyl-KDO(2)-lipid IV(A) + 1 tetradecanoyl-[acp] => 1 KDO(2)-lipid A + 1 acyl-carrier protein.
http://purl.obolibrary.org/obo/UPa_UER00487	6-hydroxypseudooxynicotine from nicotine (S-isomer route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acceptor + 1 nicotine => 1 (S)-6-hydroxynicotine + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00488	6-hydroxypseudooxynicotine from nicotine (R-isomer route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-6-hydroxynicotine + 1 H(2)O + 1 O(2) => 1 6-hydroxypseudooxynicotine + 1 H(2)O(2).
http://purl.obolibrary.org/obo/UPa_UER00489	2,6-dihydroxypyridine and 4-(methylamino)butanoate from 6-hydroxypseudooxynicotine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-hydroxypseudooxynicotine + 1 H(2)O + 1 acceptor => 1 2,6-dihydroxypseudooxynicotine + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00490	2,6-dihydroxypyridine and 4-(methylamino)butanoate from 6-hydroxypseudooxynicotine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,6-dihydroxypseudooxynicotine + 1 H(2)O => 1 2,6-dihydroxypyridine + 1 4-(methylamino)butanoate.
http://purl.obolibrary.org/obo/UPa_UER00491	UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 2 NAD(+) + 1 UDP-alpha-D-glucose => 2 H(+) + 2 NADH + 1 UDP-alpha-D-glucuronate.
http://purl.obolibrary.org/obo/UPa_UER00492	UDP-4-deoxy-4-formamido-beta-L-arabinose from UDP-alpha-D-glucuronate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 UDP-alpha-D-glucuronate => 1 CO(2) + 1 H(+) + 1 NADH + 1 UDP-beta-L-threo-pentopyranos-4-ulose.
http://purl.obolibrary.org/obo/UPa_UER00493	UDP-4-deoxy-4-formamido-beta-L-arabinose from UDP-alpha-D-glucuronate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 UDP-beta-L-threo-pentopyranos-4-ulose => 1 2-oxoglutarate + 1 UDP-4-amino-4-deoxy-L-arabinose.
http://purl.obolibrary.org/obo/UPa_UER00494	UDP-4-deoxy-4-formamido-beta-L-arabinose from UDP-alpha-D-glucuronate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 10-formyl-5,6,7,8-tetrahydrofolate + 1 UDP-4-amino-4-deoxy-L-arabinose => 1 5,6,7,8-tetrahydrofolate + 1 UDP-4-deoxy-4-formamido-beta-L-arabinose.
http://purl.obolibrary.org/obo/UPa_UER00495	4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 UDP-4-deoxy-4-formamido-beta-L-arabinose + 1 di-trans,poly-cis-undecaprenyl phosphate => 1 4-deoxy-4-formamido-alphaL-arabinose undecaprenyl phosphate + 1 UDP.
http://purl.obolibrary.org/obo/UPa_UER00496	4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-deoxy-4-formamido-alphaL-arabinose undecaprenyl phosphate + 1 H(2)O => 1 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00497	D-alanine from L-alanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-alanine => 1 D-alanine.
http://purl.obolibrary.org/obo/UPa_UER00498	NH(3) and pyruvate from D-alanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-alanine + 1 H(2)O + 1 acceptor => 1 NH(3) + 1 pyruvate + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00499	cyanurate from atrazine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 atrazine => 1 HCl + 1 hydroxyatrazine.
http://purl.obolibrary.org/obo/UPa_UER00500	cyanurate from atrazine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 hydroxyatrazine => 1 N-isopropylammelide + 1 ethylamine.
http://purl.obolibrary.org/obo/UPa_UER00501	cyanurate from atrazine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-isopropylammelide => 1 cyanurate + 1 isopropylamine.
http://purl.obolibrary.org/obo/UPa_UER00502	biuret from cyanurate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 cyanurate => 1 CO(2) + 1 biuret.
http://purl.obolibrary.org/obo/UPa_UER00503	phosphatidylglycerol from CDP-diacylglycerol: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-diacylglycerol + 1 sn-glycerol 3-phosphate => 1 CMP + 1 phosphatidylglycerophosphate.
http://purl.obolibrary.org/obo/UPa_UER00504	phosphatidylglycerol from CDP-diacylglycerol: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 phosphatidylglycerophosphate => 1 phosphate + 1 phosphatidylglycerol.
http://purl.obolibrary.org/obo/UPa_UER00505	glycine from L-threonine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-threonine + 1 NAD(+) => 1 H(+) + 1 L-2-amino-3-oxobutanoic acid + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00506	glycine from L-threonine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CoA + 1 L-2-amino-3-oxobutanoic acid => 1 acetyl-CoA + 1 glycine.
http://purl.obolibrary.org/obo/UPa_UER00507	propanoate from L-threonine: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-threonine => 1 2-oxobutanoate + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00508	propanoate from L-threonine: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxobutanoate + 1 CoA => 1 formate + 1 propanoyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00509	propanoate from L-threonine: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 phosphate + 1 propanoyl-CoA => 1 CoA + 1 propanoyl phosphate.
http://purl.obolibrary.org/obo/UPa_UER00510	propanoate from L-threonine: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ADP + 1 propanoyl phosphate => 1 ATP + 1 propanoate.
http://purl.obolibrary.org/obo/UPa_UER00511	CDP-3,6-dideoxy-D-mannose from CTP and alpha-D-glucose 1-phosphate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CTP + 1 alpha-D-glucose 1-phosphate => 1 CDP-glucose + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00512	CDP-3,6-dideoxy-D-mannose from CTP and alpha-D-glucose 1-phosphate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-glucose => 1 CDP-4-dehydro-6-deoxy-D-glucose + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00513	CDP-3,6-dideoxy-D-mannose from CTP and alpha-D-glucose 1-phosphate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		CDP-4-dehydro-6-deoxy-D-glucose + H(+) + [NADH or NADPH] => CDP-4-dehydro-3,6-dideoxy-D-glucose + H(2)O + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00514	CDP-3,6-dideoxy-D-mannose from CTP and alpha-D-glucose 1-phosphate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-4-dehydro-3,6-dideoxy-D-glucose + 1 H(+) + 1 NADPH => 1 CDP-3,6-dideoxy-D-glucose + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00515	CDP-3,6-dideoxy-D-mannose from CTP and alpha-D-glucose 1-phosphate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-3,6-dideoxy-D-glucose => 1 CDP-3,6-dideoxy-D-mannose.
http://purl.obolibrary.org/obo/UPa_UER00516	alpha-ribazole from 5,6-dimethylbenzimidazole: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,6-dimethylbenzimidazole + 1 nicotinate D-ribonucleotide => 1 H(+) + 1 alpha-ribazole 5'-phosphate + 1 nicotinate.
http://purl.obolibrary.org/obo/UPa_UER00517	alpha-ribazole from 5,6-dimethylbenzimidazole: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 alpha-ribazole 5'-phosphate => 1 alpha-ribazole + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00518	D-glyceraldehyde 3-phosphate and pyruvate from D-galactonate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-galactonate => 1 2-dehydro-3-deoxy-D-galactonate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00519	D-glyceraldehyde 3-phosphate and pyruvate from D-galactonate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-dehydro-3-deoxy-D-galactonate + 1 ATP => 1 6-phospho-2-dehydro-3-deoxy-D-galactonic acid + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00520	D-glyceraldehyde 3-phosphate and pyruvate from D-galactonate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-phospho-2-dehydro-3-deoxy-D-galactonic acid => 1 D-glyceraldehyde 3-phosphate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00521	vindoline from tabersonine: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 tabersonine => 1 16-hydroxytabersonine + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00522	vindoline from tabersonine: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 16-hydroxytabersonine + 1 S-adenosyl-L-methionine => 1 16-methoxytabersonine + 1 H(+) + 1 S-adenosyl-L-homocysteine.
http://purl.obolibrary.org/obo/UPa_UER00523	vindoline from tabersonine: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 16-methoxytabersonine + 1 H(2)O => 1 3-hydroxy-16-methoxy-2,3-dihydrotabersonine.
http://purl.obolibrary.org/obo/UPa_UER00524	vindoline from tabersonine: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-hydroxy-16-methoxy-2,3-dihydrotabersonine + 1 S-adenosyl-L-methionine => 1 S-adenosyl-L-homocysteine + 1 desacetoxyvindoline.
http://purl.obolibrary.org/obo/UPa_UER00525	vindoline from tabersonine: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 O(2) + 1 desacetoxyvindoline => 1 CO(2) + 1 deacetylvindoline + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00526	vindoline from tabersonine: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetyl-CoA + 1 deacetylvindoline => 1 CoA + 1 vindoline.
http://purl.obolibrary.org/obo/UPa_UER00527	D-glucuronate from myo-inositol: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 myo-inositol => 1 D-glucuronate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00528	alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-fructose 6-phosphate + 1 L-glutamine => 1 L-glutamate + 1 alpha-D-glucosamine 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00529	N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetyl-CoA + 1 alpha-D-glucosamine 6-phosphate => 1 CoA + 1 N-acetyl-D-glucosamine 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00530	N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-acetyl-D-glucosamine 6-phosphate => 1 N-acetyl-alpha-D-glucosamine 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00531	N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 alpha-D-glucosamine 6-phosphate => 1 alpha-D-glucosamine 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00532	N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetyl-CoA + 1 alpha-D-glucosamine 1-phosphate => 1 CoA + 1 N-acetyl-alpha-D-glucosamine 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00533	UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-acetyl-alpha-D-glucosamine 1-phosphate + 1 UTP => 1 UDP-N-acetyl-alpha-D-glucosamine + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00535	D-glucose from alpha,alpha-trehalose: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 alpha,alpha-trehalose => 2 D-glucose.
http://purl.obolibrary.org/obo/UPa_UER00536	hypotaurine from 2-aminoethanethiol: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-aminoethanethiol + 1 O(2) => 1 hypotaurine.
http://purl.obolibrary.org/obo/UPa_UER00537	hypotaurine from L-cysteine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-cysteine + 1 O(2) => 1 3-sulfino-L-alanine.
http://purl.obolibrary.org/obo/UPa_UER00538	hypotaurine from L-cysteine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-sulfino-L-alanine => 1 CO(2) + 1 hypotaurine.
http://purl.obolibrary.org/obo/UPa_UER00539	taurine from hypotaurine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 hypotaurine => 1 H(+) + 1 NADH + 1 taurine.
http://purl.obolibrary.org/obo/UPa_UER00540	taurine from L-cysteine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-cysteine + 1 sulfite => 1 L-cysteate + 1 hydrogen sulfide.
http://purl.obolibrary.org/obo/UPa_UER00541	taurine from L-cysteine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-cysteate => 1 CO(2) + 1 taurine.
http://purl.obolibrary.org/obo/UPa_UER00542	aminoacetaldehyde and sulfite from taurine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 O(2) + 1 taurine => 1 CO(2) + 1 aminoacetaldehyde + 1 succinate + 1 sulfite.
http://purl.obolibrary.org/obo/UPa_UER00543	acetyl phosphate and sulfite from taurine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 pyruvate + 1 taurine => 1 L-alanine + 1 sulfoacetaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00544	acetyl phosphate and sulfite from taurine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 phosphate + 1 sulfoacetaldehyde => 1 acetyl phosphate + 1 sulfite.
http://purl.obolibrary.org/obo/UPa_UER00545	sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-fructose 6-phosphate + 1 UDP-alpha-D-glucose => 1 UDP + 1 sucrose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00546	sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 sucrose 6-phosphate => 1 phosphate + 1 sucrose.
http://purl.obolibrary.org/obo/UPa_UER00547	3,4',5-trihydroxystilbene from trans-4-coumarate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 CoA + 1 trans-4-coumarate => 1 4-coumaroyl-CoA + 1 AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00548	3,4',5-trihydroxystilbene from trans-4-coumarate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-coumaroyl-CoA + 3 malonyl-CoA => 1 3,4',5-trihydroxystilbene + 4 CO(2) + 4 CoA.
http://purl.obolibrary.org/obo/UPa_UER00549	N-formimidoyl-L-glutamate from L-histidine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-histidine => 1 NH(3) + 1 trans-urocanate.
http://purl.obolibrary.org/obo/UPa_UER00550	N-formimidoyl-L-glutamate from L-histidine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 trans-urocanate => 1 4-imidazolone-5-propanoate.
http://purl.obolibrary.org/obo/UPa_UER00551	N-formimidoyl-L-glutamate from L-histidine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-imidazolone-5-propanoate + 1 H(2)O => 1 N-formimidoyl-L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00552	L-glutamate from N-formimidoyl-L-glutamate (hydrolase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-formimidoyl-L-glutamate => 1 L-glutamate + 1 formamide.
http://purl.obolibrary.org/obo/UPa_UCR04872	N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05046	H(2)O + formamidopyrimidine nucleoside triphosphate = 2,5-diaminopyrimidine nucleoside triphosphate + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05048	2,5-diaminopyrimidine nucleoside triphosphate = 2,5-diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05049	H(2)O + N-succinyl-L-glutamate 5-semialdehyde + NAD(+) = H(+) + N(2)-succinyl-L-glutamic acid + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05068	(2R,3R)-2,3-dihydroxy-3-methylpentanoic acid + NADP(+) = (R)-3-hydroxy-3-methyl-2-oxopentanoate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05069	(S)-2-acetyl-2-hydroxybutanoic acid = (R)-3-hydroxy-3-methyl-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05070	(2R,3R)-2,3-dihydroxy-3-methylpentanoic acid = (S)-3-methyl-2-oxopentanoate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05071	(S)-2-acetolactate = 2-oxo-3-hydroxyisovalerate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05074	3-deoxy-D-manno-octulosonyl-lipid IV((A)) + CMP-3-deoxy-D-manno-octulosonate = CMP + di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05075	lauroyl-KDO(2)-lipid IV(A) + tetradecanoyl-[acp] = KDO(2)-lipid A + acyl-carrier protein	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05085	2-oxoglutarate + 4-(phosphonooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05123	(S)-norcoclaurine + S-adenosyl-L-methionine = (S)-coclaurine + S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05146	di[3-deoxy-D-manno-octulosonyl]-lipid IV(A) + dodecanoyl-[acyl-carrier protein] = acyl-carrier protein + lauroyl-KDO(2)-lipid IV(A)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05149	2 S-adenosyl-L-methionine + precorrin-6B = CO(2) + 2 S-adenosyl-L-homocysteine + precorrin-8X	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05150	NADP(+) + precorrin-6B = H(+) + NADPH + precorrin-6A	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05176	ADP-D-glycero-beta-D-manno-heptose = ADP-L-glycero-beta-D-manno-heptose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05177	precorrin-8X = hydrogenobyrinic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05180	S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin-4	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05181	S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin-5	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05217	H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05218	FMNH(2) + 2 cob(II)yrinate a,c-diamide = FMN + 2 H(+) + 2 cob(I)yrinic acid a,c-diamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05219	S-adenosyl-L-homocysteine + acetate + precorrin-6A = H(2)O + S-adenosyl-L-methionine + precorrin-5	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05220	ATP + cob(I)yrinic acid a,c-diamide = adenosylcob(III)yrinic acid a,c-diamide + triphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05221	ATP + adenosylcobinamide = ADP + adenosylcobinamide phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05222	GTP + adenosylcobinamide phosphate = adenosylcobinamide-GDP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05223	GMP + adenosylcobalamin = adenosylcobinamide-GDP + alpha-ribazole	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05224	2 ATP + 2 H(2)O + 2 L-glutamine + hydrogenobyrinic acid = 2 ADP + 2 L-glutamate + hydrogenobyrinic acid a,c-diamide + 2 phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05225	4 ATP + 4 H(2)O + 4 L-glutamine + adenosylcob(III)yrinic acid a,c-diamide = 4 ADP + 4 L-glutamate + adenosylcobyrinic acid a,c-diamide + 4 phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05226	(R)-1-aminopropan-2-ol + adenosylcobyrinic acid a,c-diamide = H(2)O + adenosylcobinamide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05227	ATP + Co(2+) + H(2)O + hydrogenobyrinic acid a,c-diamide = ADP + H(+) + cob(II)yrinate a,c-diamide + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05239	NAD(+) + cis-3-phenylcyclohexa-3,5-diene-1,2-diol = H(+) + NADH + biphenyl-2,3-diol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05240	NAD(+) + cis-2,3-dihydroxy-2,3-dihydro-p-cumic acid = 2,3-dihydroxy-p-cumic acid + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05247	H(+) + NADH + O(2) + p-cumate = NAD(+) + cis-2,3-dihydroxy-2,3-dihydro-p-cumic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05248	2,3-dihydroxy-p-cumic acid + O(2) = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05263	H(+) + NADH + O(2) + biphenyl = NAD(+) + cis-3-phenylcyclohexa-3,5-diene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05275	NAD(+) + cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid = 4,5-dihydroxyphthalate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05284	1,2-dichloroethane + H(2)O = 2-chloroethanol + HCl	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05285	2-chloroethanol + 2 ferricytochrome c = 2 H(+) + chloroacetaldehyde + 2 ferrocytochrome c	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05286	H(2)O + NAD(+) + chloroacetaldehyde = H(+) + NADH + chloroacetic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05287	H(2)O + chloroacetic acid = HCl + glycolate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05320	2-oxoglutarate + O(2) + taurine = CO(2) + aminoacetaldehyde + succinate + sulfite	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05332	acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + N-acetyl-alpha-D-glucosamine 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05338	D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05339	D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05357	H(2)O + amidinoproclavaminic acid = proclavaminic acid + urea	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05360	2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid + H(2)O = 2-hydroxy-2,4-pentadienoate + salicylate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05361	2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid + H(2)O = 2-hydroxymuconate + catechol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05364	2-hydroxy-6-oxo-7-methylocta-2,4-dienoic acid + H(2)O = 2-hydroxy-2,4-pentadienoate + 2-methylpropanoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05377	2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoic acid = 2-hydroxy-6-oxo-7-methylocta-2,4-dienoic acid + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05378	6-phospho-5-dehydro-2-deoxy-D-gluconic acid = 3-oxopropanoate + glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05411	O(2) + biphenyl-2,2',3-triol = 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05413	2,2',3-trihydroxy-diphenyl ether + O(2) = 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05434	H(+) + NADH + O(2) + dibenzofuran = NAD(+) + biphenyl-2,2',3-triol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05439	H(+) + NADH + O(2) + dibenzo-p-dioxin = 2,2',3-trihydroxy-diphenyl ether + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05465	D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05466	2-oxoglutarate + O(2) + deoxyamidinoproclavaminic acid = CO(2) + amidinoproclavaminic acid + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05467	ATP + N(2)-(2-carboxyethyl)-L-arginine = AMP + deoxyamidinoproclavaminic acid + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05468	2-oxoglutarate + O(2) + proclavaminic acid = CO(2) + H(2)O + dihydroclavaminic acid + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05469	2-oxoglutarate + O(2) + dihydroclavaminic acid = CO(2) + H(2)O + clavaminate + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05470	clavaminate = clavulanate-9-aldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05471	H(+) + NADPH + clavulanate-9-aldehyde = NADP(+) + clavulanate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05552	NH(3) + chorismate = 4-amino-4-deoxychorismate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05553	4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05554	2-ureidoglycine + H(2)O = (S)-ureidoglycolate + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05558	H(2)O + atrazine = HCl + hydroxyatrazine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05559	H(2)O + hydroxyatrazine = N-isopropylammelide + ethylamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05560	H(2)O + N-isopropylammelide = cyanurate + isopropylamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05605	2-dehydro-3-deoxy-6-phospho-D-gluconic acid = D-glyceraldehyde 3-phosphate + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05608	galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05621	H(+) + NADH + O(2) + benzoate = (1R,6S)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05633	2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05634	4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05636	D-glyceraldehyde 3-phosphate + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05637	4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05639	14-demethyllanosterol + NADP(+) = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05640	3 H(+) + 3 NADPH + 3 O(2) + lanosterol = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + 4 H(2)O + 3 NADP(+) + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05641	NADP(+) + ergosterol = H(+) + NADPH + ergosta-5,7,22,24(28)-tetraen-3beta-ol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05644	ATP + D-glycero-beta-D-manno-heptose 1-phosphate = ADP-D-glycero-beta-D-manno-heptose + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05646	ATP + D-glycero-beta-D-manno-heptose 7-phosphate = ADP + D-glycero-beta-D-manno-heptose 1,7-diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05647	D-glycero-beta-D-manno-heptose 1,7-diphosphate + H(2)O = D-glycero-beta-D-manno-heptose 1-phosphate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05651	phosphate + sulfoacetaldehyde = acetyl phosphate + sulfite	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05652	pyruvate + taurine = L-alanine + sulfoacetaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05661	2-deoxy-5-keto-D-gluconic acid + ATP = 6-phospho-5-dehydro-2-deoxy-D-gluconic acid + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05681	4-(phosphonooxy)-L-threonine + NAD(+) = 2-amino-3-oxo-4-phosphonooxybutyrate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05688	2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05692	GDP-L-fucose + NADP(+) = GDP-4-dehydro-6-deoxy-D-mannose + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05728	(Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05732	(S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05765	geranyl diphosphate = (-)-alpha-pinene + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05766	geranyl diphosphate = (-)-beta-pinene + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05768	3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglyceric acid + GDP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05774	3-sulfopyruvate = CO(2) + sulfoacetaldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05784	(4R)-limonene 1,2-epoxide + H(2)O = (1S,2S,4R)-limonene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05789	(2R)-O-phospho-3-sulfolactic acid + H(2)O = (R)-3-sulfolactate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05790	2-(alpha-D-mannosyl)-3-phosphoglyceric acid + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05794	CDP-diacylglycerol + choline = CMP + phosphatidylcholine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05807	Co(2+) + sirohydrochlorin = 2 H(+) + cobalt-precorrin-2	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05808	S-adenosyl-L-methionine + cobalt-precorrin-2 = S-adenosyl-L-homocysteine + cobalt-factor III	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05809	S-adenosyl-L-methionine + cobalt-precorrin 3 = S-adenosyl-L-homocysteine + cobalt-precorrin 4	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05810	S-adenosyl-L-methionine + cobalt-precorrin 4 = S-adenosyl-L-homocysteine + cobalt-precorrin 5A	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05812	H(+) + NADH + cobalt-precorrin-6A = NAD(+) + cobalt-precorrin-6B	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05813	2 S-adenosyl-L-methionine + cobalt-precorrin-6B = CO(2) + 2 S-adenosyl-L-homocysteine + cobalt-precorrin 8	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05814	cobalt-precorrin 8 = cob(III)yrinic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05815	2 ATP + 2 H(2)O + 2 L-glutamine + cob(III)yrinic acid = 2 ADP + 2 L-glutamate + cob(II)yrinate a,c-diamide + 2 phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05820	D-sorbitol + protein N(pi)-phospho-L-histidine = D-sorbitol 6-phosphate + protein-L-histidine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05838	1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + phosphate + pyridoxine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05850	L-ribulose 5-phosphate = D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05855	H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05856	16-methoxytabersonine + H(2)O = 3-hydroxy-16-methoxy-2,3-dihydrotabersonine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05857	2-oxoglutarate + O(2) + desacetoxyvindoline = CO(2) + deacetylvindoline + succinate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05884	(2E)-4-hydroxy-3-methylbutenyl diphosphate + H(+) + NADPH = H(2)O + NADP(+) + isopentenyl diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR05885	16-hydroxytabersonine + S-adenosyl-L-methionine = 16-methoxytabersonine + H(+) + S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06117	(4S,6R)-trans-carveol + NAD(+) = (S)-carvone + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06119	(4R)-limonene + H(+) + NADPH + O(2) = (4S,6R)-trans-carveol + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06120	geranyl diphosphate = (4R)-limonene + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06171	L-allo-threonine = acetaldehyde + glycine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06180	L-tartrate + NAD(+) = 2-hydroxy-3-oxosuccinate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06223	H(+) + NADPH + 2 farnesyl diphosphate = NADP(+) + 2 diphosphate + squalene	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06305	geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06306	O(2) + reduced acceptor + taxa-4,11-diene = H(2)O + acceptor + taxa-4(20),11-dien-5alpha-ol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06307	acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06309	H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06310	10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06311	10-deacetylbaccatin III + acetyl-CoA = CoA + baccatin III	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06372	(S)-carvone + reduced acceptor = (1R,4S)-isodihydrocarvone + acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06398	(4R)-limonene + H(+) + NADH + O(2) = (4R)-limonene 1,2-epoxide + H(2)O + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06399	(1S,2S,4R)-limonene-1,2-diol + NAD(+) = (1S,4R)-1-hydroxylimonen-2-one + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06558	GTP + adenosylcobinamide = GDP + adenosylcobinamide phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06601	5-hydroxyisouric acid + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06604	5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylic acid = (S)-allantoin + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06782	3-phenylpropanoate + H(+) + NADH + O(2) = NAD(+) + cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06784	NAD(+) + cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol = 3-(2,3-dihydroxyphenyl)propanoate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06786	3-(3-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06836	ATP + D-ribose 1,5-bisphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ADP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06837	alpha-D-ribose 1-phosphate = D-ribose 1,5-bisphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06868	N-methylethanolamine phosphate + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + phosphodimethylethanolamine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06869	S-adenosyl-L-methionine + phosphodimethylethanolamine = S-adenosyl-L-homocysteine + phosphocholine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06895	2 S-adenosyl-L-methionine + coproporphyrinogen-III = 2 5'-deoxyadenosine + 2 CO(2) + 2 L-methionine + protoporphyrinogen-IX	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06897	2-hydroxy-hept-2,4-diene-1,7-dioic acid + H(2)O = 2,4-dihydroxyhept-2-enedioic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06974	ATP + N(1)-(5-phospho-D-ribosyl)glycinamide + formate = ADP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06975	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ATP + formate = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + ADP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06977	L-aspartate 4-semialdehyde + L-glutamate = 2-oxoglutarate + L-2,4-diaminobutanoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06978	L-2,4-diaminobutanoate + acetyl-CoA = CoA + N(4)-acetyl-L-2,4-diaminobutyric acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06979	N(4)-acetyl-L-2,4-diaminobutyric acid = H(2)O + L-ectoine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06982	formaldehyde + glutathione = S-(hydroxymethyl)glutathione	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06983	NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH + S-formylglutathione	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06987	2-oxobutanoate + CoA = formate + propanoyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06989	cis,cis-muconate = (S)-5-oxo-2,5-dihydro-2-furylacetic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR06990	(S)-5-oxo-2,5-dihydro-2-furylacetic acid = 5-oxo-4,5-dihydro-2-furylacetate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07125	3-dehydro-L-gulonate 6-phosphate + H(+) = CO(2) + L-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07133	D-sorbitol 6-phosphate + NAD(+) = D-fructose 6-phosphate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07136	(R)-3-sulfolactate + NAD(+) = 3-sulfopyruvate + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07140	NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH + S-formylglutathione	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07170	(R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07211	L-phenylalanine + O(2) + tetrahydrobiopterin = 4a-hydroxytetrahydrobiopterin + L-tyrosine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07213	L-tryptophan + O(2) + tetrahydrobiopterin = 4a-hydroxytetrahydrobiopterin + 5-hydroxy-L-tryptophan	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07214	1-aminocyclopropanecarboxylate + L-ascorbate + O(2) = CO(2) + 2 H(2)O + L-dehydroascorbate + ethylene + hydrogen cyanide	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07219	H(2)O + NADP(+) + dimethylallyl diphosphate = (2E)-4-hydroxy-3-methylbutenyl diphosphate + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07243	S-adenosyl-L-methionine + sarcosine = N,N-dimethylglycine + S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07244	N,N-dimethylglycine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + betaine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07262	1,4-dihydroxy-2-naphthoyl-CoA + H(2)O = 1,4-dihydroxy-2-naphthoate + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07263	2-succinylbenzoyl-CoA = 1,4-dihydroxy-2-naphthoyl-CoA + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07276	2-oxoglutarate + L-arogenate = L-glutamate + prephenate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07280	5-amino-6-(5-phosphoribitylamino)uracil + H(2)O = 5-amino-6-(D-ribitylamino)uracil + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07281	D-ribulose 5-phosphate = 2-hydroxy-3-oxobutyl phosphate + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07290	formyl-CoA + oxalate = formate + oxalyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07305	H(2)O + cyanurate = CO(2) + biuret	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07307	2 H(2)O + dCTP = NH(3) + dUMP + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07320	violaxanthin = capsorubin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07321	antheraxanthin = capsanthin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07324	D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07364	1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07392	S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07393	5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07394	2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate + H(2)O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07396	4-methylthio-2-oxobutanoate + L-glutamate = 2-oxoglutarate + L-methionine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07399	H(2)O + acetyl-CoA + pyruvate = (R)-citramalate + CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07403	H(+) + NADPH + O(2) + indole = H(2)O + NADP(+) + indolin-2-one	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07404	5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07405	5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07406	2-amino-3-oxo-4-phosphonooxybutyrate = 3-amino-2-oxopropyl phosphate + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07407	L-aspartate + NADP(+) = H(+) + NADPH + iminoaspartate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07409	2 H(+) + O(2) + choline + 2 reduced ferredoxin = 2 H(2)O + betaine aldehyde + 2 oxidized ferredoxin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07410	L-aspartate + NAD(+) = H(+) + NADH + iminoaspartate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07411	H(2)O + farnesyl diphosphate + protoheme = diphosphate + heme O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07412	heme O = heme A	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07414	ATP + L-glutamate + putrescine = ADP + gamma-L-glutamylputrescine + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07415	H(2)O + O(2) + gamma-L-glutamylputrescine = H(2)O(2) + NH(3) + gamma-glutamyl-4-aminobutanal	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07417	H(2)O + NAD(+) + gamma-glutamyl-4-aminobutanal = 4-(L-gamma-glutamylamino)butanoic acid + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07418	H(2)O + NADP(+) + gamma-glutamyl-4-aminobutanal = 4-(L-gamma-glutamylamino)butanoic acid + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07419	4-(L-gamma-glutamylamino)butanoic acid + H(2)O = 4-aminobutanoate + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07421	H(+) + NADPH + O(2) + indolin-2-one = 3-hydroxyindolin-2-one + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07422	3-hydroxyindolin-2-one + H(+) + NADPH + O(2) = 2-hydroxy-1,4-benzoxazin-3-one + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07423	2-hydroxy-1,4-benzoxazin-3-one + H(+) + NADPH + O(2) = 2,4-dihydroxy-1,4-benzoxazin-3-one + H(2)O + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07476	(2R)-O-phospho-3-sulfolactic acid = phosphoenolpyruvate + sulfite	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07494	4alpha-methylzymosterol-4-carboxylic acid + NADP(+) = 3-dehydro-4-methylzymosterol + CO(2) + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07495	3-dehydro-4-methylzymosterol + H(+) + NADPH = 4-alpha-methylzymosterol + NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07496	4-alpha-methylzymosterol = zymosterol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07497	fecosterol = episterol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07505	NADP(+) + episterol = 5,7,24(28)-ergostatrienol + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07506	5,7,24(28)-ergostatrienol + NADP(+) = H(+) + NADPH + ergosta-5,7,22,24(28)-tetraen-3beta-ol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07509	14-demethyllanosterol + 3 H(+) + 3 NADPH + 3 O(2) = 4alpha-methylzymosterol-4-carboxylic acid + 4 H(2)O + 3 NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07514	6-hydroxypseudooxynicotine + H(2)O + acceptor = 2,6-dihydroxypseudooxynicotine + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07515	2,6-dihydroxypseudooxynicotine + H(2)O = 2,6-dihydroxypyridine + 4-(methylamino)butanoate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07613	2-oxoglutarate + LL-2,6-diaminopimelate = (S)-tetrahydrodipicolinate + H(2)O + L-glutamate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07629	3-oxo-3-ureidopropanoic acid + H(2)O = malonate + urea	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07647	H(2)O + farnesyl diphosphate = diphosphate + germacradienol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07648	farnesyl diphosphate = diphosphate + germacrene D	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07650	L-2,4-diaminobutanoate = 1,3-diaminopropane + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07652	2 farnesyl diphosphate = dehydrosqualene + 2 diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07653	3 FAD + dehydrosqualene = 4,4'-diaponeurosporene + 3 FADH2	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07654	4,4'-diaponeurosporene + 3 O(2) + 3 reduced acceptor = 4,4'-diaponeurosporenic acid + 4 H(2)O + 3 acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07655	4,4'-diaponeurosporenic acid = glycosyl-4,4'-diaponeurosporenic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07656	glycosyl-4,4'-diaponeurosporenic acid = staphyloxanthin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07658	NAD(+) + UDP-alpha-D-glucuronate = CO(2) + H(+) + NADH + UDP-beta-L-threo-pentopyranos-4-ulose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07659	L-glutamate + UDP-beta-L-threo-pentopyranos-4-ulose = 2-oxoglutarate + UDP-4-amino-4-deoxy-L-arabinose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07660	10-formyl-5,6,7,8-tetrahydrofolate + UDP-4-amino-4-deoxy-L-arabinose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07661	UDP-4-deoxy-4-formamido-beta-L-arabinose + di-trans,poly-cis-undecaprenyl phosphate = 4-deoxy-4-formamido-alphaL-arabinose undecaprenyl phosphate + UDP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07662	4-deoxy-4-formamido-alphaL-arabinose undecaprenyl phosphate + H(2)O = 4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate + formate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07671	L-ascorbate + protein N(pi)-phospho-L-histidine = L-ascorbate 6-phosphate + protein-L-histidine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07672	GDP-alpha-D-mannose = GDP-L-gulose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07673	GDP-L-gulose = GDP-L-galactose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07674	H(2)O + beta-L-galactose 1-phosphate = alpha-L-galactose + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07675	NAD(+) + alpha-L-galactose = H(+) + L-Galactono-1,4-lactone + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07677	H(2)O + L-ascorbate 6-phosphate = 3-dehydro-L-gulonate 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07678	GDP-L-galactose + phosphate = GDP + beta-L-galactose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07766	apoprotein + octanoyl-[acyl-carrier-protein] = acyl-carrier protein + protein N(6)-(octanoyl)lysine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07767	2 S-adenosyl-L-methionine + protein N(6)-(octanoyl)lysine + 2 sulfur donor = 2 5'-deoxyadenosine + 2 L-methionine + protein N(6)-(lipoyl)lysine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07770	ATP + lipoate = diphosphate + lipoyl-AMP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07771	apoprotein + lipoyl-AMP = AMP + protein N(6)-(lipoyl)lysine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07772	H(2)O + cobalt-precorrin 5A = acetaldehyde + cobalt-precorrin 5B	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07773	S-adenosyl-L-methionine + cobalt-precorrin 5B = S-adenosyl-L-homocysteine + cobalt-precorrin-6A	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07916	2 geranylgeranyl diphosphate = all-trans-phytoene + 2 diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07946	H(2)O + acceptor + nicotine = (R)-6-hydroxynicotine + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07984	6-hydroxynicotinate + 2 H(2)O = 2-formylglutarate + NH(3)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07985	2-formylglutarate + H(+) + NADH = 2-hydroxymethylglutarate + NAD(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR07986	2-hydroxymethylglutarate = 2-methyleneglutarate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08058	5,6,7,8-tetrahydromethanopterin + formaldehyde = 5,10-methylene-5,6,7,8-tetrahydromethanopterin + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08059	5,10-methylene-5,6,7,8-tetrahydromethanopterin + NADP(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08060	H(2)O + N-formylmethanofuran = formate + methanofuran	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08124	ATP + fructoselysine = ADP + fructoselysine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08125	H(2)O + fructoselysine 6-phosphate = D-glucose 6-phosphate + L-lysine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08165	2-oxoglutarate + isochorismate = 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid + CO(2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08166	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid + pyruvate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08171	N-(3'R)-debenzoyltaxol + benzoyl-CoA = CoA + taxol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08172	baccatin III + beta-phenylalanoyl-CoA = CoA + N-(3'R)-debenzoyl-2'-deoxytaxol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08173	N-(3'R)-debenzoyl-2'-deoxytaxol + O(2) + reduced acceptor = H(2)O + N-(3'R)-debenzoyltaxol + acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08193	N-acetyl-D-glucosamine 6-phosphate = N-acetyl-alpha-D-glucosamine 1-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08211	H(2)O + O(2) + betaine aldehyde = H(2)O(2) + betaine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08218	ATP + L-serine + tRNA(Sec) = AMP + L-seryl-tRNA(Sec) + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08219	L-seryl-tRNA(Sec) + selenophosphate = phosphate + selenocysteinyl-tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08223	ATP + L-seryl-tRNA(Sec) = ADP + O-phosphoseryl-tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08224	H(2)O + O-phosphoseryl-tRNA(Sec) + selenophosphate = 2 phosphate + selenocysteinyl-tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08247	beta-D-ribopyranose = beta-D-ribofuranose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08503	5-deoxy-D-glucuronic acid = 2-deoxy-5-keto-D-gluconic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08549	2-oxoglutarate + CoA + NAD(+) = CO(2) + H(+) + NADH + succinyl-CoA	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08557	NAD(+) + choline = H(+) + NADH + betaine aldehyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08574	CTP + riboflavin = CDP + FMN	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08603	3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O = 5-deoxy-D-glucuronic acid	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08615	H(2)O + UDP-alpha-D-glucuronate = D-glucuronate + UDP	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08617	D-glucose 6-phosphate = 2-deoxy-scyllo-inosose + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08656	2 H(+) + L-tyrosine + 2 NADPH + 2 O(2) = (Z)-(4-hydroxyphenyl)acetaldehyde oxime + CO(2) + 3 H(2)O + 2 NADP(+)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08689	2-C-methyl-D-erythritol 2,4-cyclic diphosphate + 2 reduced ferredoxin = (2E)-4-hydroxy-3-methylbutenyl diphosphate + H(2)O + 2 oxidized ferredoxin	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08716	cobalt-factor III = cobalt-precorrin 3	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08890	2-deoxy-scyllo-inosose + L-glutamine = 2-deoxy-scyllo-inosamine + 2-oxoglutaramate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08891	3-amino-2,3-dideoxy-scyllo-inosose + L-glutamine = 2-deoxystreptamine + 2-oxoglutaramate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08892	2-deoxy-scyllo-inosamine + NAD(+) = 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08947	D-fructose 6-phosphate + GDP-alpha-D-mannose = GDP + beta-D-fructofuranosyl alpha-D-mannopyranoside 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR08982	H(2)O + beta-D-fructofuranosyl alpha-D-mannopyranoside 6-phosphate = beta-D-fructofuranosyl alpha-D-mannopyranoside + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09736	S-adenosyl-L-methionine + demethylmenaquinol = S-adenosyl-L-homocysteine + menaquinol	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09770	ATP + D-glycero-alpha-D-manno-heptose 7-phosphate = ADP + D-glycero-alpha-D-manno-heptose 1,7-diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09771	D-glycero-alpha-D-manno-heptose 1,7-diphosphate + H(2)O = D-glycero-alpha-D-manno-heptose 1-phosphate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09772	D-glycero-alpha-D-manno-heptose 1-phosphate + GTP = GDP-D-glycero-alpha-D-manno-heptose + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09775	ATP + L-alpha-aminoadipate + [LysW] = ADP + [LysW]-L-2-aminoadipate + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09776	ATP + [LysW]-L-2-aminoadipate = ADP + [LysW]-L-2-aminoadipyl 6-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09777	H(+) + NADPH + [LysW]-L-2-aminoadipyl 6-phosphate = NADP(+) + [LysW]-L-2-aminoadipate 6-semialdehyde + phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09778	L-glutamate + [LysW]-L-2-aminoadipate 6-semialdehyde = 2-oxoglutarate + [LysW]-L-lysine	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR09779	H(2)O + [LysW]-L-lysine = L-lysine + [LysW]	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR10130	2-deoxy-scyllo-inosamine + NADP(+) = 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + NADPH	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR10147	L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(2)O	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCR10757	1,4-dihydroxy-2-naphthoate + all-trans-polyprenyl diphosphate = CO(2) + demethylmenaquinol + diphosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00012	1-deoxy-D-xylulose 5-phosphate = 4-methyl-5-(2-phosphoethyl)-thiazole	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00016	D-alanine + H(2)O + acceptor = NH(3) + pyruvate + reduced acceptor	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00018	2 sedoheptulose 7-phosphate = D-glycero-alpha-D-manno-heptose 7-phosphate + D-glycero-beta-D-manno-heptose 7-phosphate	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00032	pectate = 4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonic acid + pectate(n-2)	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00036	beta-D-ribofuranose = D-ribose	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00044	8-amino-7-oxononanoate + L-lysine = 7,8-diaminononanoate + L-2-aminoadipate 6-semialdahyde	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00047	10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate = 10-deacetyl-2-debenzoylbaccatin III	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UCY00048	4-amino-5-hydroxymethyl-2-methylpyrimidine = 5-amino-1-(5-phospho-D-ribosyl)imidazole	http://purl.obolibrary.org/obo/UPa_UCR00000	reaction		
http://purl.obolibrary.org/obo/UPa_UER00553	L-glutamate from N-formimidoyl-L-glutamate (deiminase route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-formimidoyl-L-glutamate => 1 N-formyl-L-glutamate + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00554	L-glutamate from N-formimidoyl-L-glutamate (deiminase route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-formyl-L-glutamate => 1 L-glutamate + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00555	L-glutamate from N-formimidoyl-L-glutamate (transferase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,6,7,8-tetrahydrofolate + 1 N-formimidoyl-L-glutamate => 1 5-formiminotetrahydrofolate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00556	staphyloxanthin from farnesyl diphosphate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		2 farnesyl diphosphate => 1 dehydrosqualene + 2 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00557	staphyloxanthin from farnesyl diphosphate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		3 FAD + 1 dehydrosqualene => 1 4,4'-diaponeurosporene + 3 FADH2.
http://purl.obolibrary.org/obo/UPa_UER00558	staphyloxanthin from farnesyl diphosphate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4,4'-diaponeurosporene + 3 O(2) + 3 reduced acceptor => 1 4,4'-diaponeurosporenic acid + 4 H(2)O + 3 acceptor.
http://purl.obolibrary.org/obo/UPa_UER00559	staphyloxanthin from farnesyl diphosphate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4,4'-diaponeurosporenic acid => 1 glycosyl-4,4'-diaponeurosporenic acid.
http://purl.obolibrary.org/obo/UPa_UER00560	staphyloxanthin from farnesyl diphosphate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 glycosyl-4,4'-diaponeurosporenic acid => 1 staphyloxanthin.
http://purl.obolibrary.org/obo/UPa_UER00561	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 5/10	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 cobalt-precorrin 5A => 1 acetaldehyde + 1 cobalt-precorrin 5B.
http://purl.obolibrary.org/obo/UPa_UER00562	ethylene from S-adenosyl-L-methionine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine => 1 1-aminocyclopropanecarboxylate + 1 S-methyl-5'-thioadenosine.
http://purl.obolibrary.org/obo/UPa_UER00563	ethylene from S-adenosyl-L-methionine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-aminocyclopropanecarboxylate + 1 L-ascorbate + 1 O(2) => 1 CO(2) + 2 H(2)O + 1 L-dehydroascorbate + 1 ethylene + 1 hydrogen cyanide.
http://purl.obolibrary.org/obo/UPa_UER00564	geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 farnesyl diphosphate + 1 isopentenyl diphosphate => 1 diphosphate + 1 geranylgeranyl diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00565	D-xylulose 5-phosphate from L-arabinose (bacterial route): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arabinose => 1 L-ribulose.
http://purl.obolibrary.org/obo/UPa_UER00566	D-xylulose 5-phosphate from L-arabinose (bacterial route): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-ribulose => 1 ADP + 1 L-ribulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00567	D-xylulose 5-phosphate from L-arabinose (bacterial route): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-ribulose 5-phosphate => 1 D-xylulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00568	2-dehydro-3-deoxy-L-arabinonate from L-arabinose: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arabinose + 1 NAD(+) => 1 H(+) + 1 L-arabinono-1,4-lactone + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00569	2-dehydro-3-deoxy-L-arabinonate from L-arabinose: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-arabinono-1,4-lactone => 1 L-arabinonate.
http://purl.obolibrary.org/obo/UPa_UER00570	2-dehydro-3-deoxy-L-arabinonate from L-arabinose: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arabinonate => 1 2-dehydro-3-deoxy-L-arabinonate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00571	glycolaldehyde and pyruvate from 2-dehydro-3-deoxy-L-arabinonate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-dehydro-3-deoxy-L-arabinonate => 1 glycolaldehyde + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00572	2-oxoglutarate from 2-dehydro-3-deoxy-L-arabinonate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-dehydro-3-deoxy-L-arabinonate => 1 2,5-dioxopentanoate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00573	2-oxoglutarate from 2-dehydro-3-deoxy-L-arabinonate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,5-dioxopentanoate + 1 H(2)O + 1 NADP(+) => 1 2-oxoglutarate + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00574	D-xylulose 5-phosphate from L-arabinose (fungal route): step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		H(+) + L-arabinose + [NADH or NADPH] => L-arabinitol + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00575	D-xylulose 5-phosphate from L-arabinose (fungal route): step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arabinitol + 1 NAD(+) => 1 H(+) + 1 L-xylulose + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00576	D-xylulose 5-phosphate from L-arabinose (fungal route): step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-xylulose + 1 NADPH => 1 NADP(+) + 1 xylitol.
http://purl.obolibrary.org/obo/UPa_UER00577	D-xylulose 5-phosphate from L-arabinose (fungal route): step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 xylitol => 1 D-xylulose + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00578	D-xylulose 5-phosphate from L-arabinose (fungal route): step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-xylulose => 1 ADP + 1 D-xylulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00579	creatine from L-arginine and glycine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arginine + 1 glycine => 1 L-ornithine + 1 guanidinoacetate.
http://purl.obolibrary.org/obo/UPa_UER00580	creatine from L-arginine and glycine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 guanidinoacetate => 1 S-adenosyl-L-homocysteine + 1 creatine.
http://purl.obolibrary.org/obo/UPa_UER00581	pentalenene from farnesyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 farnesyl diphosphate => 1 diphosphate + 1 pentalenene.
http://purl.obolibrary.org/obo/UPa_UER00582	aristolochene from farnesyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 farnesyl diphosphate => 1 aristolochene + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00583	germacradienol from farnesyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 farnesyl diphosphate => 1 diphosphate + 1 germacradienol.
http://purl.obolibrary.org/obo/UPa_UER00584	germacrene D from farnesyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 farnesyl diphosphate => 1 diphosphate + 1 germacrene D.
http://purl.obolibrary.org/obo/UPa_UER00585	NH(3) and pyruvate from L-alanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-alanine + 1 NAD(+) => 1 H(+) + 1 NADH + 1 NH(3) + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00586	pyruvate from L-alanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 L-alanine => 1 L-glutamate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00587	betaine aldehyde from choline (dehydrogenase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 choline => 1 H(+) + 1 NADH + 1 betaine aldehyde.
http://purl.obolibrary.org/obo/UPa_UER00588	4-pyridoxate from pyridoxal: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 pyridoxal => 1 4-pyridoxolactone + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00589	4-pyridoxate from pyridoxal: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-pyridoxolactone + 1 H(2)O => 1 4-pyridoxate.
http://purl.obolibrary.org/obo/UPa_UER00590	pyridoxal from pyridoxine (oxidase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 pyridoxine => 1 H(2)O(2) + 1 pyridoxal.
http://purl.obolibrary.org/obo/UPa_UER00591	crotonoyl-CoA from L-glutamate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-glutamate + 1 NAD(+) => 1 2-oxoglutarate + 1 H(+) + 1 NADH + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00592	protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 apoprotein + 1 octanoyl-[acyl-carrier-protein] => 1 acyl-carrier protein + 1 protein N(6)-(octanoyl)lysine.
http://purl.obolibrary.org/obo/UPa_UER00593	protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		2 S-adenosyl-L-methionine + 1 protein N(6)-(octanoyl)lysine + 2 sulfur donor => 2 5'-deoxyadenosine + 2 L-methionine + 1 protein N(6)-(lipoyl)lysine.
http://purl.obolibrary.org/obo/UPa_UER00594	protein N(6)-(lipoyl)lysine from lipoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 lipoate => 1 diphosphate + 1 lipoyl-AMP.
http://purl.obolibrary.org/obo/UPa_UER00595	protein N(6)-(lipoyl)lysine from lipoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 apoprotein + 1 lipoyl-AMP => 1 AMP + 1 protein N(6)-(lipoyl)lysine.
http://purl.obolibrary.org/obo/UPa_UER00596	thiamine phosphate from thiamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 thiamine => 1 ADP + 1 thiamine phosphate.
http://purl.obolibrary.org/obo/UPa_UER00597	thiamine diphosphate from thiamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 thiamine => 1 AMP + 1 thiamine diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00598	CO(2) and formate from oxalate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 formyl-CoA + 1 oxalate => 1 formate + 1 oxalyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00599	CO(2) and formate from oxalate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 oxalyl-CoA => 1 CO(2) + 1 formyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00600	NAD(+) from nicotinamide D-ribonucleotide: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 nicotinamide D-ribonucleotide => 1 NAD(+) + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00601	glycerone phosphate from L-rhamnose: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-rhamnose => 1 L-rhamnulose.
http://purl.obolibrary.org/obo/UPa_UER00602	glycerone phosphate from L-rhamnose: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-rhamnulose => 1 ADP + 1 L-rhamnulose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00603	glycerone phosphate from L-rhamnose: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-rhamnulose 1-phosphate => 1 L-lactaldehyde + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00604	lactose 6-phosphate from lactose (PTS route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 lactose + 1 protein N(pi)-phospho-L-histidine => 1 lactose 6-phosphate + 1 protein-L-histidine.
http://purl.obolibrary.org/obo/UPa_UER00605	D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 lactose 6-phosphate => 1 D-galactose 6-phosphate + 1 beta-D-glucose.
http://purl.obolibrary.org/obo/UPa_UER00606	GDP-D-glycero-alpha-D-manno-heptose from D-glycero-alpha-D-manno-heptose 7-phosphate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-glycero-alpha-D-manno-heptose 7-phosphate => 1 ADP + 1 D-glycero-alpha-D-manno-heptose 1,7-diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00607	GDP-D-glycero-alpha-D-manno-heptose from D-glycero-alpha-D-manno-heptose 7-phosphate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glycero-alpha-D-manno-heptose 1,7-diphosphate + 1 H(2)O => 1 D-glycero-alpha-D-manno-heptose 1-phosphate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00608	GDP-D-glycero-alpha-D-manno-heptose from D-glycero-alpha-D-manno-heptose 7-phosphate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glycero-alpha-D-manno-heptose 1-phosphate + 1 GTP => 1 GDP-D-glycero-alpha-D-manno-heptose + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00609	cyclic 2,3-diphosphoglycerate from 2-phospho-D-glycerate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-phospho-D-glycerate + 1 ATP => 1 2,3-bisphospho-D-glycerate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00610	cyclic 2,3-diphosphoglycerate from 2-phospho-D-glycerate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,3-bisphospho-D-glycerate + 1 ATP => 1 ADP + 1 cyclic 2,3-diphosphoglycerate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00611	(S)-lactate from pyruvate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 pyruvate => 1 (S)-lactate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00612	CDP-diacylglycerol from sn-glycerol 3-phosphate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acyl-CoA + 1 sn-glycerol 3-phosphate => 1 1-acyl-sn-glycerol 3-phosphate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00613	CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-acyl-sn-glycerol 3-phosphate + 1 acyl-CoA => 1 CoA + 1 phosphatidate.
http://purl.obolibrary.org/obo/UPa_UER00614	CDP-diacylglycerol from sn-glycerol 3-phosphate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CTP + 1 phosphatidate => 1 CDP-diacylglycerol + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00615	phosphatidylethanolamine from CDP-diacylglycerol: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-diacylglycerol + 1 L-serine => 1 CMP + 1 phosphatidylserine.
http://purl.obolibrary.org/obo/UPa_UER00616	phosphatidylethanolamine from CDP-diacylglycerol: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 phosphatidylserine => 1 CO(2) + 1 phosphatidylethanolamine.
http://purl.obolibrary.org/obo/UPa_UER00617	acetate and pyruvate from L-glutamate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate => 1 (2S,3S)-3-methyl-L-aspartate.
http://purl.obolibrary.org/obo/UPa_UER00618	acetate and pyruvate from L-glutamate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2S,3S)-3-methyl-L-aspartate => 1 NH(3) + 1 mesaconate.
http://purl.obolibrary.org/obo/UPa_UER00619	acetate and pyruvate from L-glutamate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 mesaconate => 1 L-citramalate.
http://purl.obolibrary.org/obo/UPa_UER00620	acetate and pyruvate from L-glutamate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-citramalate => 1 acetate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00621	formate from formaldehyde (glutathione route): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 formaldehyde + 1 glutathione => 1 S-(hydroxymethyl)glutathione.
http://purl.obolibrary.org/obo/UPa_UER00622	formate from formaldehyde (glutathione route): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		S-(hydroxymethyl)glutathione + [NAD(+) or NADP(+)] => H(+) + S-formylglutathione + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00623	formate from formaldehyde (glutathione route): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 S-formylglutathione => 1 formate + 1 glutathione.
http://purl.obolibrary.org/obo/UPa_UER00624	L-lactaldehyde and glycerone phosphate from L-fucose: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-fucose => 1 L-fuculose.
http://purl.obolibrary.org/obo/UPa_UER00625	L-lactaldehyde and glycerone phosphate from L-fucose: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-fuculose => 1 ADP + 1 L-fuculose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00626	L-lactaldehyde and glycerone phosphate from L-fucose: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-fuculose 1-phosphate => 1 L-lactaldehyde + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00627	2,5-dioxopentanoate from D-glucarate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucarate => 1 5-dehydro-4-deoxy-D-glucarate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00628	2,5-dioxopentanoate from D-glucarate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-dehydro-4-deoxy-D-glucarate => 1 2,5-dioxopentanoate + 1 CO(2) + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00629	D-glycerate from galactarate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 galactarate => 1 5-dehydro-4-deoxy-D-glucarate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00630	D-glycerate from galactarate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-dehydro-4-deoxy-D-glucarate => 1 2-hydroxy-3-oxopropanoate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00631	D-glycerate from galactarate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		2-hydroxy-3-oxopropanoate + H(+) + [NADH or NADPH] => D-glycerate + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00632	uridine from cytidine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 cytidine => 1 NH(3) + 1 uridine.
http://purl.obolibrary.org/obo/UPa_UER00633	uracil from uridine (phosphorylase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 phosphate + 1 uridine => 1 alpha-D-ribose 1-phosphate + 1 uracil.
http://purl.obolibrary.org/obo/UPa_UER00634	uracil from uridine (hydrolase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 uridine => 1 D-ribose + 1 uracil.
http://purl.obolibrary.org/obo/UPa_UER00635	uracil from cytosine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 cytosine => 1 NH(3) + 1 uracil.
http://purl.obolibrary.org/obo/UPa_UER00636	UMP from uracil: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 uracil => 1 UMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00637	UMP from uridine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 uridine => 1 ADP + 1 UMP.
http://purl.obolibrary.org/obo/UPa_UER00638	dTMP from thymine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-deoxy-alpha-D-ribose 1-phosphate + 1 thymine => 1 phosphate + 1 thymidine.
http://purl.obolibrary.org/obo/UPa_UER00639	dTMP from thymine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 thymidine => 1 ADP + 1 dTMP.
http://purl.obolibrary.org/obo/UPa_UER00640	CTP from cytidine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 cytidine => 1 ADP + 1 CMP.
http://purl.obolibrary.org/obo/UPa_UER00641	CTP from cytidine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 CMP => 1 ADP + 1 CDP.
http://purl.obolibrary.org/obo/UPa_UER00642	CTP from cytidine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 CDP => 1 ADP + 1 CTP.
http://purl.obolibrary.org/obo/UPa_UER00643	malonate and urea from uracil: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acceptor + 1 uracil => 1 barbiturate + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00644	malonate and urea from uracil: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 barbiturate => 1 3-oxo-3-ureidopropanoic acid.
http://purl.obolibrary.org/obo/UPa_UER00645	malonate and urea from uracil: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-oxo-3-ureidopropanoic acid + 1 H(2)O => 1 malonate + 1 urea.
http://purl.obolibrary.org/obo/UPa_UER00646	AMP from adenine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 adenine => 1 AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00647	IMP from inosine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 inosine => 1 ADP + 1 IMP.
http://purl.obolibrary.org/obo/UPa_UER00648	IMP from hypoxanthine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 hypoxanthine => 1 IMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00649	AMP from ADP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 ADP => 1 AMP + 1 ATP.
http://purl.obolibrary.org/obo/UPa_UER00650	(S)-allantoin from urate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O(2) + 1 urate => 1 5-hydroxyisouric acid + 1 H(2)O(2).
http://purl.obolibrary.org/obo/UPa_UER00651	(S)-allantoin from urate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-hydroxyisouric acid + 1 H(2)O => 1 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylic acid.
http://purl.obolibrary.org/obo/UPa_UER00652	(S)-allantoin from urate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylic acid => 1 (S)-allantoin + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00653	allantoate from (S)-allantoin: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-allantoin + 1 H(2)O => 1 allantoate.
http://purl.obolibrary.org/obo/UPa_UER00654	(S)-ureidoglycolate from allantoate (aminidohydrolase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 allantoate => 1 (S)-ureidoglycolate + 1 urea.
http://purl.obolibrary.org/obo/UPa_UER00655	(S)-ureidoglycolate from allantoate (amidohydrolase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 allantoate => 1 (S)-ureidoglycolate + 1 CO(2) + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00656	glyoxylate from (S)-ureidoglycolate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-ureidoglycolate + 1 H(2)O => 1 CO(2) + 2 NH(3) + 1 glyoxylate.
http://purl.obolibrary.org/obo/UPa_UER00657	oxalurate from (S)-ureidoglycolate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		(S)-ureidoglycolate + [NAD(+) or NADP(+)] => H(+) + oxalurate + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00658	XMP from xanthine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 xanthine => 1 XMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00659	AMP from adenosine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 adenosine => 1 ADP + 1 AMP.
http://purl.obolibrary.org/obo/UPa_UER00660	xanthine from guanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 guanine => 1 NH(3) + 1 xanthine.
http://purl.obolibrary.org/obo/UPa_UER00661	urate from hypoxanthine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 hypoxanthine => 1 H(+) + 1 NADH + 1 xanthine.
http://purl.obolibrary.org/obo/UPa_UER00662	urate from hypoxanthine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 xanthine => 1 H(+) + 1 NADH + 1 urate.
http://purl.obolibrary.org/obo/UPa_UER00663	IMP from AMP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 AMP + 1 H(2)O => 1 IMP + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00664	phosphatidate from CDP-diacylglycerol: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-diacylglycerol + 1 H(2)O => 1 CMP + 1 phosphatidate.
http://purl.obolibrary.org/obo/UPa_UER00665	dUMP from dCTP (dUTP route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 dCTP => 1 NH(3) + 1 dUTP.
http://purl.obolibrary.org/obo/UPa_UER00666	dUMP from dCTP (dUTP route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 dUTP => 1 dUMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00667	dUMP from dCTP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(2)O + 1 dCTP => 1 NH(3) + 1 dUMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00668	glycerone phosphate from glycerol (oxidative route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 glycerol => 1 H(+) + 1 NADH + 1 glycerone.
http://purl.obolibrary.org/obo/UPa_UER00669	glycerone phosphate from glycerol (oxidative route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 glycerone => 1 ADP + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00670	propane-1,3-diol from glycerol (reductive route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 glycerol => 1 3-hydroxypropanal + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00671	propane-1,3-diol from glycerol (reductive route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-hydroxypropanal + 1 H(+) + 1 NADH => 1 NAD(+) + 1 propane-1,3-diol.
http://purl.obolibrary.org/obo/UPa_UER00672	sn-glycerol 3-phosphate from glycerol: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 glycerol => 1 ADP + 1 sn-glycerol 3-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00673	glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 Quinone + 1 sn-glycerol 3-phosphate => 1 Hydroquinone + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00674	glycerone phosphate from sn-glycerol 3-phosphate (aerobic route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 Quinone + 1 sn-glycerol 3-phosphate => 1 Hydroquinone + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00675	(R)-lactate from methylglyoxal: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 glutathione + 1 methylglyoxal => 1 (R)-S-lactoylglutathione.
http://purl.obolibrary.org/obo/UPa_UER00676	(R)-lactate from methylglyoxal: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-S-lactoylglutathione + 1 H(2)O => 1 (R)-lactate + 1 glutathione.
http://purl.obolibrary.org/obo/UPa_UER00677	(R,R)-butane-2,3-diol from pyruvate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		2 pyruvate => 1 (S)-2-acetolactate + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00678	(R,R)-butane-2,3-diol from pyruvate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-2-acetolactate => 1 (R)-acetoin + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00679	(R,R)-butane-2,3-diol from pyruvate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-acetoin + 1 H(+) + 1 NADH => 1 (R,R)-butane-2,3-diol + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00680	D-fructose 6-phosphate from N-acetylneuraminate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-acetylneuraminate => 1 N-acetyl-D-mannosamine + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00681	D-fructose 6-phosphate from N-acetylneuraminate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 N-acetyl-D-mannosamine => 1 ADP + 1 N-acetyl-D-mannosamine 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00682	D-fructose 6-phosphate from N-acetylneuraminate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-acetyl-D-mannosamine 6-phosphate => 1 N-acetyl-D-glucosamine 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00683	D-fructose 6-phosphate from N-acetylneuraminate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-acetyl-D-glucosamine 6-phosphate => 1 acetate + 1 alpha-D-glucosamine 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00684	D-fructose 6-phosphate from N-acetylneuraminate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 alpha-D-glucosamine 6-phosphate => 1 D-fructose 6-phosphate + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00685	crotonoyl-CoA from L-glutamate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 FADH2 => 1 2-hydroxyglutarate + 1 FAD.
http://purl.obolibrary.org/obo/UPa_UER00686	crotonoyl-CoA from L-glutamate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxyglutarate + 1 acetyl-CoA => 1 2-hydroxyglutaryl-CoA + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00687	crotonoyl-CoA from L-glutamate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxyglutaryl-CoA => 1 H(2)O + 1 glutaconyl-1-CoA.
http://purl.obolibrary.org/obo/UPa_UER00688	crotonoyl-CoA from L-glutamate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 glutaconyl-1-CoA => 1 CO(2) + 1 crotonoyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00689	L-glutamate from 2-oxoglutarate and L-glutamine (NADP(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 H(+) + 1 L-glutamine + 1 NADPH => 2 L-glutamate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00690	L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 H(+) + 1 L-glutamine + 1 NADH => 2 L-glutamate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00691	L-glutamate from 2-oxoglutarate and L-glutamine (ferredoxin route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 2 H(+) + 1 L-glutamine + 2 reduced ferredoxin => 2 L-glutamate + 2 oxidized ferredoxin.
http://purl.obolibrary.org/obo/UPa_UER00692	5,10-methenyl-5,6,7,8-tetrahydromethanopterin from CO(2): step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CO(2) + 1 methanofuran + 1 reduced acceptor => 1 H(2)O + 1 N-formylmethanofuran + 1 acceptor.
http://purl.obolibrary.org/obo/UPa_UER00693	5,10-methenyl-5,6,7,8-tetrahydromethanopterin from CO(2): step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,6,7,8-tetrahydromethanopterin + 1 N-formylmethanofuran => 1 N(5)-formyl-5,6,7,8-tetrahydromethanopterin + 1 methanofuran.
http://purl.obolibrary.org/obo/UPa_UER00694	5,10-methenyl-5,6,7,8-tetrahydromethanopterin from CO(2): step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 N(5)-formyl-5,6,7,8-tetrahydromethanopterin => 1 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00695	5,10-methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8-tetrahydromethanopterin (coenzyme F420 route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,5-dihydro-coenzyme F(420) + 1 5,10-methenyl-5,6,7,8-tetrahydromethanopterin => 1 5,10-methylene-5,6,7,8-tetrahydromethanopterin + 1 coenzyme F420.
http://purl.obolibrary.org/obo/UPa_UER00696	5,10-methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8-tetrahydromethanopterin (hydrogen route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + 1 H(2) => 1 5,10-methylene-5,6,7,8-tetrahydromethanopterin + 1 H(+).
http://purl.obolibrary.org/obo/UPa_UER00697	methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,5-dihydro-coenzyme F(420) + 1 5,10-methylene-5,6,7,8-tetrahydromethanopterin => 1 5-methyl-5,6,7,8-tetrahydromethanopterin + 1 coenzyme F420.
http://purl.obolibrary.org/obo/UPa_UER00698	methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-methyl-5,6,7,8-tetrahydromethanopterin + 1 coenzyme M => 1 5,6,7,8-tetrahydromethanopterin + 1 methyl-coenzyme M.
http://purl.obolibrary.org/obo/UPa_UER00699	methane from methyl-coenzyme M: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 coenzyme B + 1 methyl-coenzyme M => 1 coenzyme M-coenzyme B heterodisulfide + 1 methane.
http://purl.obolibrary.org/obo/UPa_UER00700	coenzyme B and coenzyme M from coenzyme M-coenzyme B heterodisulfide: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 coenzyme M-coenzyme B heterodisulfide + 1 dihydromethanophenazine => 1 coenzyme B + 1 coenzyme M + 1 methanophenazine.
http://purl.obolibrary.org/obo/UPa_UER00701	formate from formaldehyde (H(4)MPT route): step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,6,7,8-tetrahydromethanopterin + 1 formaldehyde => 1 5,10-methylene-5,6,7,8-tetrahydromethanopterin + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00702	formate from formaldehyde (H(4)MPT route): step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,10-methylene-5,6,7,8-tetrahydromethanopterin + 1 NADP(+) => 1 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00703	formate from formaldehyde (H(4)MPT route): step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + 1 H(2)O => 1 H(+) + 1 N(5)-formyl-5,6,7,8-tetrahydromethanopterin.
http://purl.obolibrary.org/obo/UPa_UER00704	formate from formaldehyde (H(4)MPT route): step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N(5)-formyl-5,6,7,8-tetrahydromethanopterin + 1 methanofuran => 1 5,6,7,8-tetrahydromethanopterin + 1 N-formylmethanofuran.
http://purl.obolibrary.org/obo/UPa_UER00705	formate from formaldehyde (H(4)MPT route): step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 N-formylmethanofuran => 1 formate + 1 methanofuran.
http://purl.obolibrary.org/obo/UPa_UER00706	dinitrogen from nitrate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 nitrate + 1 reduced acceptor => 1 H(2)O + 1 acceptor + 1 nitrite.
http://purl.obolibrary.org/obo/UPa_UER00707	dinitrogen from nitrate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 ferrocytochrome c + 1 nitrite => 1 H(2)O + 1 ferricytochrome c + 1 nitric oxide.
http://purl.obolibrary.org/obo/UPa_UER00708	dinitrogen from nitrate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(+) + 2 ferrocytochrome c + 2 nitric oxide => 1 H(2)O + 2 ferricytochrome c + 1 nitrous oxide.
http://purl.obolibrary.org/obo/UPa_UER00709	dinitrogen from nitrate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(+) + 2 ferrocytochrome c + 1 nitrous oxide => 1 H(2)O + 1 dinitrogen + 2 ferricytochrome c.
http://purl.obolibrary.org/obo/UPa_UER00710	acetyl-CoA from malonyl-CoA: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 malonyl-CoA => 1 CO(2) + 1 acetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00711	malonyl-CoA from acetyl-CoA: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 acetyl-CoA + 1 bicarbonate => 1 ADP + 1 malonyl-CoA + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00712	heme O from protoheme: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 farnesyl diphosphate + 1 protoheme => 1 diphosphate + 1 heme O.
http://purl.obolibrary.org/obo/UPa_UER00713	heme A from heme O: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 heme O => 1 heme A.
http://purl.obolibrary.org/obo/UPa_UER00714	D-tagatose 6-phosphate from D-galactose 6-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-galactose 6-phosphate => 1 D-tagatose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00715	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-tagatose 6-phosphate => 1 ADP + 1 D-tagatose 1,6-bisphosphate.
http://purl.obolibrary.org/obo/UPa_UER00716	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-tagatose 1,6-bisphosphate => 1 D-glyceraldehyde 3-phosphate + 1 glycerone phosphate.
http://purl.obolibrary.org/obo/UPa_UER00717	isocitrate from oxaloacetate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acetyl-CoA + 1 oxaloacetate => 1 CoA + 1 citrate.
http://purl.obolibrary.org/obo/UPa_UER00718	isocitrate from oxaloacetate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 citrate => 1 isocitrate.
http://purl.obolibrary.org/obo/UPa_UER00719	(S)-malate from isocitrate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 isocitrate => 1 glyoxylate + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00720	(S)-malate from isocitrate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acetyl-CoA + 1 glyoxylate => 1 (S)-malate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00721	oxaloacetate from (S)-malate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-malate + 1 NAD(+) => 1 H(+) + 1 NADH + 1 oxaloacetate.
http://purl.obolibrary.org/obo/UPa_UER00722	phenylacetate from L-phenylalanine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-phenylalanine => 1 2-phenylethylamine + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00723	phenylacetate from L-phenylalanine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-phenylethylamine + 1 H(2)O + 1 O(2) => 1 H(2)O(2) + 1 NH(3) + 1 phenylacetaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00724	phenylacetate from L-phenylalanine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 phenylacetaldehyde => 1 H(+) + 1 NADH + 1 phenylacetate.
http://purl.obolibrary.org/obo/UPa_UER00725	trans-cinnamate from L-phenylalanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-phenylalanine => 1 NH(3) + 1 trans-cinnamate.
http://purl.obolibrary.org/obo/UPa_UER00726	kynurenate from L-kynurenine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 L-kynurenine => 1 4-(2-aminophenyl)-2,4-dioxobutanoate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00727	kynurenate from L-kynurenine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-(2-aminophenyl)-2,4-dioxobutanoate => 1 H(2)O + 1 kynurenate.
http://purl.obolibrary.org/obo/UPa_UER00728	3,4-dihydroxybenzoate from phthalate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 phthalate => 1 NAD(+) + 1 cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid.
http://purl.obolibrary.org/obo/UPa_UER00729	3,4-dihydroxybenzoate from phthalate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid => 1 4,5-dihydroxyphthalate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00730	3,4-dihydroxybenzoate from phthalate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4,5-dihydroxyphthalate => 1 3,4-dihydroxybenzoate + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00731	1,3-diaminopropane from L-aspartate 4-semialdehyde: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate 4-semialdehyde + 1 L-glutamate => 1 2-oxoglutarate + 1 L-2,4-diaminobutanoate.
http://purl.obolibrary.org/obo/UPa_UER00732	1,3-diaminopropane from L-aspartate 4-semialdehyde: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-2,4-diaminobutanoate => 1 1,3-diaminopropane + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00733	dopamine from L-tyrosine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-tyrosine + 1 O(2) => 1 H(2)O + 1 L-dopa.
http://purl.obolibrary.org/obo/UPa_UER00734	dopamine from L-tyrosine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-dopa => 1 CO(2) + 1 dopamine.
http://purl.obolibrary.org/obo/UPa_UER00735	(R)-noradrenaline from dopamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-ascorbate + 1 O(2) + 1 dopamine => 1 (R)-noradrenaline + 1 H(2)O + 1 L-dehydroascorbate.
http://purl.obolibrary.org/obo/UPa_UER00736	(R)-adrenaline from (R)-noradrenaline: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-noradrenaline + 1 S-adenosyl-L-methionine => 1 (R)-adrenaline + 1 S-adenosyl-L-homocysteine.
http://purl.obolibrary.org/obo/UPa_UER00737	phosphocholine from choline: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 choline => 1 ADP + 1 phosphocholine.
http://purl.obolibrary.org/obo/UPa_UER00738	phosphocholine from phosphoethanolamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 phosphoethanolamine => 1 S-adenosyl-L-homocysteine + 1 phosphocholine.
http://purl.obolibrary.org/obo/UPa_UER00739	phosphatidylcholine from phosphocholine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CTP + 1 phosphocholine => 1 CDP-choline + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00740	phosphatidylcholine from phosphocholine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,2-diacyl-sn-glycerol + 1 CDP-choline => 1 CMP + 1 phosphatidylcholine.
http://purl.obolibrary.org/obo/UPa_UER00741	phosphatidylethanolamine from ethanolamine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 ethanolamine => 1 ADP + 1 phosphoethanolamine.
http://purl.obolibrary.org/obo/UPa_UER00742	phosphatidylethanolamine from ethanolamine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CTP + 1 phosphoethanolamine => 1 CDP-ethanolamine + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00743	phosphatidylethanolamine from ethanolamine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,2-diacyl-sn-glycerol + 1 CDP-ethanolamine => 1 CMP + 1 phosphatidylethanolamine.
http://purl.obolibrary.org/obo/UPa_UER00744	dhurrin from L-tyrosine: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(+) + 1 L-tyrosine + 2 NADPH + 2 O(2) => 1 (Z)-(4-hydroxyphenyl)acetaldehyde oxime + 1 CO(2) + 3 H(2)O + 2 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00745	dhurrin from L-tyrosine: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (Z)-(4-hydroxyphenyl)acetaldehyde oxime + 1 H(+) + 1 NADPH + 1 O(2) => 1 (S)-4-hydroxymandelonitrile + 2 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00746	dhurrin from L-tyrosine: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-4-hydroxymandelonitrile + 1 UDP-alpha-D-glucose => 1 UDP + 1 dhurrin.
http://purl.obolibrary.org/obo/UPa_UER00747	AMP from 3',5'-cyclic AMP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3',5'-cyclic AMP + 1 H(2)O => 1 AMP.
http://purl.obolibrary.org/obo/UPa_UER00748	GMP from 3',5'-cyclic GMP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3',5'-cyclic GMP + 1 H(2)O => 1 GMP.
http://purl.obolibrary.org/obo/UPa_UER00749	5-valerolactone from cyclopentanol: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 cyclopentanol => 1 H(+) + 1 NADH + 1 cyclopentanone.
http://purl.obolibrary.org/obo/UPa_UER00750	5-valerolactone from cyclopentanol: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 cyclopentanone => 1 5-valerolactone + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00751	lanosterol from farnesyl diphosphate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 2 farnesyl diphosphate => 1 NADP(+) + 2 diphosphate + 1 squalene.
http://purl.obolibrary.org/obo/UPa_UER00752	lanosterol from farnesyl diphosphate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 squalene => 1 (S)-2,3-epoxysqualene + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00753	lanosterol from farnesyl diphosphate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-2,3-epoxysqualene => 1 lanosterol.
http://purl.obolibrary.org/obo/UPa_UER00754	zymosterol from lanosterol: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		3 H(+) + 3 NADPH + 3 O(2) + 1 lanosterol => 1 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + 4 H(2)O + 3 NADP(+) + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00755	zymosterol from lanosterol: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + 1 H(+) + 1 NADPH => 1 14-demethyllanosterol + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00756	zymosterol from lanosterol: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 14-demethyllanosterol + 3 H(+) + 3 NADPH + 3 O(2) => 1 4alpha-methylzymosterol-4-carboxylic acid + 4 H(2)O + 3 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00757	zymosterol from lanosterol: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4alpha-methylzymosterol-4-carboxylic acid + 1 NADP(+) => 1 3-dehydro-4-methylzymosterol + 1 CO(2) + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00758	zymosterol from lanosterol: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-dehydro-4-methylzymosterol + 1 H(+) + 1 NADPH => 1 4-alpha-methylzymosterol + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00759	zymosterol from lanosterol: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-alpha-methylzymosterol => 1 zymosterol.
http://purl.obolibrary.org/obo/UPa_UER00760	ergosterol from zymosterol: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-adenosyl-L-methionine + 1 zymosterol => 1 S-adenosyl-L-homocysteine + 1 fecosterol.
http://purl.obolibrary.org/obo/UPa_UER00761	ergosterol from zymosterol: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 fecosterol => 1 episterol.
http://purl.obolibrary.org/obo/UPa_UER00762	ergosterol from zymosterol: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NADP(+) + 1 episterol => 1 5,7,24(28)-ergostatrienol + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00763	ergosterol from zymosterol: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,7,24(28)-ergostatrienol + 1 NADP(+) => 1 H(+) + 1 NADPH + 1 ergosta-5,7,22,24(28)-tetraen-3beta-ol.
http://purl.obolibrary.org/obo/UPa_UER00764	ergosterol from zymosterol: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 ergosta-5,7,22,24(28)-tetraen-3beta-ol => 1 NADP(+) + 1 ergosterol.
http://purl.obolibrary.org/obo/UPa_UER00765	dehydro-D-arabinono-1,4-lactone from D-arabinose: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		D-arabinose + [NAD(+) or NADP(+)] => D-arabinono-1,4-lactone + H(+) + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00766	dehydro-D-arabinono-1,4-lactone from D-arabinose: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-arabinono-1,4-lactone + 1 O(2) => 1 H(2)O(2) + 1 dehydro-D-arabinono-1,4-lactone.
http://purl.obolibrary.org/obo/UPa_UER00767	acetate from ethanol: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 ethanol => 1 H(+) + 1 NADH + 1 acetaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00768	acetate from ethanol: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 acetaldehyde => 1 H(+) + 1 NADH + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00769	D-glucose 6-phosphate and lysine from fructoselysine: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 fructoselysine => 1 ADP + 1 fructoselysine 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00770	D-glucose 6-phosphate and lysine from fructoselysine: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 fructoselysine 6-phosphate => 1 D-glucose 6-phosphate + 1 L-lysine.
http://purl.obolibrary.org/obo/UPa_UER00771	UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 UDP-alpha-D-glucuronate => 1 CO(2) + 1 UDP-alpha-D-xylose.
http://purl.obolibrary.org/obo/UPa_UER00772	UDP-L-arabinose from UDP-alpha-D-xylose: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 UDP-alpha-D-xylose => 1 UDP-L-arabinose.
http://purl.obolibrary.org/obo/UPa_UER00773	all-trans-phytoene from geranylgeranyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 geranylgeranyl diphosphate => 1 all-trans-phytoene + 2 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00774	capsanthin from antheraxanthin: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 antheraxanthin => 1 capsanthin.
http://purl.obolibrary.org/obo/UPa_UER00775	capsorubin from violaxanthin: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 violaxanthin => 1 capsorubin.
http://purl.obolibrary.org/obo/UPa_UER00776	2-hydroxy-2,4-pentadienoate and salicylate from dibenzofuran: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 dibenzofuran => 1 NAD(+) + 1 biphenyl-2,2',3-triol.
http://purl.obolibrary.org/obo/UPa_UER00777	2-hydroxy-2,4-pentadienoate and salicylate from dibenzofuran: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 biphenyl-2,2',3-triol => 1 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid.
http://purl.obolibrary.org/obo/UPa_UER00778	2-hydroxy-2,4-pentadienoate and salicylate from dibenzofuran: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid + 1 H(2)O => 1 2-hydroxy-2,4-pentadienoate + 1 salicylate.
http://purl.obolibrary.org/obo/UPa_UER00779	2-hydroxymuconate and catechol from dibenzo-p-dioxin: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 dibenzo-p-dioxin => 1 2,2',3-trihydroxy-diphenyl ether + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00780	2-hydroxymuconate and catechol from dibenzo-p-dioxin: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,2',3-trihydroxy-diphenyl ether + 1 O(2) => 1 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid.
http://purl.obolibrary.org/obo/UPa_UER00781	2-hydroxymuconate and catechol from dibenzo-p-dioxin: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid + 1 H(2)O => 1 2-hydroxymuconate + 1 catechol.
http://purl.obolibrary.org/obo/UPa_UER00782	D-sorbitol 6-phosphate from D-sorbitol: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-sorbitol + 1 protein N(pi)-phospho-L-histidine => 1 D-sorbitol 6-phosphate + 1 protein-L-histidine.
http://purl.obolibrary.org/obo/UPa_UER00783	D-fructose 6-phosphate from D-sorbitol 6-phosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-sorbitol 6-phosphate + 1 NAD(+) => 1 D-fructose 6-phosphate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00784	D-sorbitol from D-fructose and D-glucose: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-fructose + 1 D-glucose => 1 D-glucono-1,5-lactone + 1 D-sorbitol.
http://purl.obolibrary.org/obo/UPa_UER00785	D-gluconate from D-glucono-1,5-lactone: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucono-1,5-lactone + 1 H(2)O => 1 D-gluconate.
http://purl.obolibrary.org/obo/UPa_UER00786	histamine from L-histidine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-histidine => 1 CO(2) + 1 histamine.
http://purl.obolibrary.org/obo/UPa_UER00787	myo-inositol from D-glucose 6-phosphate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucose 6-phosphate => 1 1D-myo-inositol 3-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00788	myo-inositol from D-glucose 6-phosphate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1D-myo-inositol 3-phosphate + 1 H(2)O => 1 myo-inositol + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00789	trans-4-coumarate from trans-cinnamate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 trans-cinnamate => 1 H(2)O + 1 NADP(+) + 1 trans-4-coumarate.
http://purl.obolibrary.org/obo/UPa_UER00790	nicotinate from nicotinamide: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 nicotinamide => 1 NH(3) + 1 nicotinate.
http://purl.obolibrary.org/obo/UPa_UER00791	3-(2,3-dihydroxyphenyl)propanoate from 3-(3-hydroxyphenyl)propanoate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-(3-hydroxyphenyl)propanoate + 1 H(+) + 1 NADH + 1 O(2) => 1 3-(2,3-dihydroxyphenyl)propanoate + 1 H(2)O + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00792	3-(2,3-dihydroxyphenyl)propanoate from 3-phenylpropanoate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-phenylpropanoate + 1 H(+) + 1 NADH + 1 O(2) => 1 NAD(+) + 1 cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol.
http://purl.obolibrary.org/obo/UPa_UER00793	3-(2,3-dihydroxyphenyl)propanoate from 3-phenylpropanoate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol => 1 3-(2,3-dihydroxyphenyl)propanoate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00794	acetaldehyde and pyruvate from 3-(2,3-dihydroxyphenyl)propanoate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-(2,3-dihydroxyphenyl)propanoate + 1 O(2) => 1 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.
http://purl.obolibrary.org/obo/UPa_UER00795	acetaldehyde and pyruvate from 3-(2,3-dihydroxyphenyl)propanoate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + 1 H(2)O => 1 2-hydroxy-2,4-pentadienoate + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00796	acetaldehyde and pyruvate from 3-(2,3-dihydroxyphenyl)propanoate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-2,4-pentadienoate + 1 H(2)O => 1 4-hydroxy-2-oxopentanoate.
http://purl.obolibrary.org/obo/UPa_UER00797	acetaldehyde and pyruvate from 3-(2,3-dihydroxyphenyl)propanoate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-hydroxy-2-oxopentanoate => 1 acetaldehyde + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00798	acetyl-CoA from acetaldehyde: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CoA + 1 NAD(+) + 1 acetaldehyde => 1 H(+) + 1 NADH + 1 acetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00799	serotonin from L-tryptophan: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-tryptophan + 1 O(2) + 1 tetrahydrobiopterin => 1 4a-hydroxytetrahydrobiopterin + 1 5-hydroxy-L-tryptophan.
http://purl.obolibrary.org/obo/UPa_UER00800	2-hydroxy-3-oxosuccinate from L-tartrate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-tartrate + 1 NAD(+) => 1 2-hydroxy-3-oxosuccinate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00801	2-hydroxy-3-oxosuccinate from meso-tartrate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 meso-tartrate => 1 2-hydroxy-3-oxosuccinate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00802	D-glycerate from 2-hydroxy-3-oxosuccinate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2-hydroxy-3-oxosuccinate + H(+) + [NADH or NADPH] => CO(2) + D-glycerate + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00803	D-glycerate from L-tartrate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-tartrate => 1 CO(2) + 1 D-glycerate.
http://purl.obolibrary.org/obo/UPa_UER00804	3-hydroxypyruvate from D-glycerate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		D-glycerate + [NAD(+) or NADP(+)] => 3-hydroxypyruvate + H(+) + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00805	4-amino-5-hydroxymethyl-2-methylpyrimidine and 5-(2-hydroxyethyl)-4-methylthiazole from thiamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 thiamine => 1 4-amino-5-hydroxymethyl-2-methylpyrimidine + 1 5-(2-hydroxyethyl)-4-methylthiazole + 1 H(+).
http://purl.obolibrary.org/obo/UPa_UER00806	taxa-4(20),11-dien-5alpha-ol from geranylgeranyl diphosphate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 geranylgeranyl diphosphate => 1 diphosphate + 1 taxa-4,11-diene.
http://purl.obolibrary.org/obo/UPa_UER00807	taxa-4(20),11-dien-5alpha-ol from geranylgeranyl diphosphate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 reduced acceptor + 1 taxa-4,11-diene => 1 H(2)O + 1 acceptor + 1 taxa-4(20),11-dien-5alpha-ol.
http://purl.obolibrary.org/obo/UPa_UER00808	10-deacetyl-2-debenzoylbaccatin III from taxa-4(20),11-dien-5alpha-ol: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetyl-CoA + 1 taxa-4(20),11-dien-5alpha-ol => 1 CoA + 1 taxa-4(20),11-dien-5alpha-yl acetate.
http://purl.obolibrary.org/obo/UPa_UER00809	10-deacetyl-2-debenzoylbaccatin III from taxa-4(20),11-dien-5alpha-ol: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 taxa-4(20),11-dien-5alpha-yl acetate => 1 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00810	baccatin III from 10-deacetyl-2-debenzoylbaccatin III: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 10-deacetyl-2-debenzoylbaccatin III + 1 benzoyl-CoA => 1 10-deacetylbaccatin III + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER00811	baccatin III from 10-deacetyl-2-debenzoylbaccatin III: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 10-deacetylbaccatin III + 1 acetyl-CoA => 1 CoA + 1 baccatin III.
http://purl.obolibrary.org/obo/UPa_UER00812	taxol from baccatin III: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 baccatin III + 1 beta-phenylalanoyl-CoA => 1 CoA + 1 N-(3'R)-debenzoyl-2'-deoxytaxol.
http://purl.obolibrary.org/obo/UPa_UER00813	taxol from baccatin III: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-(3'R)-debenzoyl-2'-deoxytaxol + 1 O(2) + 1 reduced acceptor => 1 H(2)O + 1 N-(3'R)-debenzoyltaxol + 1 acceptor.
http://purl.obolibrary.org/obo/UPa_UER00814	serotonin from L-tryptophan: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-hydroxy-L-tryptophan => 1 CO(2) + 1 serotonin.
http://purl.obolibrary.org/obo/UPa_UER00815	melatonin from serotonin: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetyl-CoA + 1 serotonin => 1 CoA + 1 N-acetylserotonin.
http://purl.obolibrary.org/obo/UPa_UER00816	melatonin from serotonin: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-acetylserotonin + 1 S-adenosyl-L-methionine => 1 S-adenosyl-L-homocysteine + 1 melatonin.
http://purl.obolibrary.org/obo/UPa_UER00817	10-deacetyl-2-debenzoylbaccatin III from taxa-4(20),11-dien-5alpha-ol: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate => 1 10-deacetyl-2-debenzoylbaccatin III.
http://purl.obolibrary.org/obo/UPa_UER00818	7,8-dihydrofolate from folate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 folate => 1 7,8-dihydrofolate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00819	tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 7,8-dihydroneopterin triphosphate => 1 6-pyruvoyl-tetrahydropterin + 1 triphosphate.
http://purl.obolibrary.org/obo/UPa_UER00820	tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-pyruvoyl-tetrahydropterin + 1 H(+) + 1 NADPH => 1 6-lactoyl-5,6,7,8-tetrahydropterin + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00821	tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-lactoyl-5,6,7,8-tetrahydropterin + 1 H(+) + 1 NADPH => 1 NADP(+) + 1 tetrahydrobiopterin.
http://purl.obolibrary.org/obo/UPa_UER00822	tetrahydrobiopterin from biopterin: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 H(+) + 2 NADPH + 1 biopterin => 2 NADP(+) + 1 tetrahydrobiopterin.
http://purl.obolibrary.org/obo/UPa_UER00823	2-dehydro-3-deoxy-D-gluconate from pectin: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		n H(2)O + 1 pectin => n methanol + 1 pectate.
http://purl.obolibrary.org/obo/UPa_UER00824	2-dehydro-3-deoxy-D-gluconate from pectin: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 pectate => 1 4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonic acid + 1 pectate(n-2).
http://purl.obolibrary.org/obo/UPa_UER00825	2-dehydro-3-deoxy-D-gluconate from pectin: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonic acid => 2 5-dehydro-4-deoxy-D-glucuronic acid.
http://purl.obolibrary.org/obo/UPa_UER00826	2-dehydro-3-deoxy-D-gluconate from pectin: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-dehydro-4-deoxy-D-glucuronic acid => 1 3-deoxy-D-glycero-hexo-2,5-diulosonate.
http://purl.obolibrary.org/obo/UPa_UER00827	2-dehydro-3-deoxy-D-gluconate from pectin: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-deoxy-D-glycero-hexo-2,5-diulosonate + 1 H(+) + 1 NADH => 1 2-dehydro-3-deoxy-D-gluconate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00828	D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-gluconate: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-dehydro-3-deoxy-D-gluconate + 1 ATP => 1 2-dehydro-3-deoxy-6-phospho-D-gluconic acid + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00829	D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-gluconate: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-dehydro-3-deoxy-6-phospho-D-gluconic acid => 1 D-glyceraldehyde 3-phosphate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00830	3-phospho-D-glycerate from glycolate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acceptor + 1 glycolate => 1 glyoxylate + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00831	3-phospho-D-glycerate from glycolate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		2 glyoxylate => 1 2-hydroxy-3-oxopropanoate + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00832	3-phospho-D-glycerate from glycolate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		2-hydroxy-3-oxopropanoate + H(+) + [NADH or NADPH] => D-glycerate + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00833	3-phospho-D-glycerate from glycolate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-glycerate => 1 3-phospho-D-glycerate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00834	glycolate from 2-phosphoglycolate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-phosphoglycolate + 1 H(2)O => 1 glycolate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00835	glutaryl-CoA from L-lysine: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 H(+) + 1 L-lysine + 1 NADPH => 1 H(2)O + 1 NADP(+) + 1 saccharopine.
http://purl.obolibrary.org/obo/UPa_UER00836	glutaryl-CoA from L-lysine: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 saccharopine => 1 H(+) + 1 L-2-aminoadipate 6-semialdahyde + 1 L-glutamate + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00837	glutaryl-CoA from L-lysine: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		H(2)O + L-2-aminoadipate 6-semialdahyde + [NAD(+) or NADP(+)] => H(+) + L-alpha-aminoadipate + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00838	glutaryl-CoA from L-lysine: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 L-alpha-aminoadipate => 1 2-oxoadipate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00839	glutaryl-CoA from L-lysine: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoadipate + 1 Enzyme N6-(lipoyl)lysine => 1 CO(2) + 1 S(8)-glutaryldihydrolipoamide.
http://purl.obolibrary.org/obo/UPa_UER00840	glutaryl-CoA from L-lysine: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CoA + 1 S(8)-glutaryldihydrolipoamide => 1 Enzyme N6-(dihydrolipoyl)lysine + 1 glutaryl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00841	glutarate from L-lysine: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-lysine + 1 acetyl phosphate => 1 N(6)-acetyl-L-lysine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00842	glutarate from L-lysine: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 N(6)-acetyl-L-lysine => 1 6-acetamido-2-oxohexanoate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00843	glutarate from L-lysine: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-acetamido-2-oxohexanoate + 1 H(2)O + 1 NAD(+) => 1 5-acetamidopentanoate + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00844	glutarate from L-lysine: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-acetamidopentanoate + 1 H(2)O => 1 5-aminopentanoate + 1 acetate.
http://purl.obolibrary.org/obo/UPa_UER00845	glutarate from L-lysine: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 5-aminopentanoate => 1 5-oxopentanoate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00846	glutarate from L-lysine: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-oxopentanoate + 1 H(2)O + 1 NAD(+) => 1 H(+) + 1 NADH + 1 glutarate.
http://purl.obolibrary.org/obo/UPa_UER00847	2,4-dihydroxy-1,4-benzoxazin-3-one from indoleglycerol phosphate: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 indoleglycerol phosphate => 1 D-glyceraldehyde 3-phosphate + 1 indole.
http://purl.obolibrary.org/obo/UPa_UER00848	2,4-dihydroxy-1,4-benzoxazin-3-one from indoleglycerol phosphate: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 indole => 1 H(2)O + 1 NADP(+) + 1 indolin-2-one.
http://purl.obolibrary.org/obo/UPa_UER00849	2,4-dihydroxy-1,4-benzoxazin-3-one from indoleglycerol phosphate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 O(2) + 1 indolin-2-one => 1 3-hydroxyindolin-2-one + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00850	2,4-dihydroxy-1,4-benzoxazin-3-one from indoleglycerol phosphate: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-hydroxyindolin-2-one + 1 H(+) + 1 NADPH + 1 O(2) => 1 2-hydroxy-1,4-benzoxazin-3-one + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00851	2,4-dihydroxy-1,4-benzoxazin-3-one from indoleglycerol phosphate: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-1,4-benzoxazin-3-one + 1 H(+) + 1 NADPH + 1 O(2) => 1 2,4-dihydroxy-1,4-benzoxazin-3-one + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00852	benzoate from (R)-mandelate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-mandelate => 1 (S)-mandelate.
http://purl.obolibrary.org/obo/UPa_UER00853	benzoate from (R)-mandelate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-mandelate + 1 acceptor => 1 phenylglyoxylate + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00854	benzoate from (R)-mandelate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 phenylglyoxylate => 1 CO(2) + 1 benzaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00855	benzoate from (R)-mandelate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		H(2)O + benzaldehyde + [NAD(+) or NADP(+)] => H(+) + benzoate + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00856	tetrahydrobiopterin from dihydrobiopterin: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		H(+) + dihydrobiopterin + [NADH or NADPH] => tetrahydrobiopterin + [NAD(+) or NADP(+)].
http://purl.obolibrary.org/obo/UPa_UER00857	4-methyl-2-oxopentanoate from L-leucine (aminotransferase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 L-leucine => 1 4-methyl-2-oxopentanoate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00858	4-methyl-2-oxopentanoate from L-leucine (dehydrogenase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-leucine + 1 NAD(+) => 1 4-methyl-2-oxopentanoate + 1 H(+) + 1 NADH + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER00859	3-isovaleryl-CoA from 4-methyl-2-oxopentanoate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-methyl-2-oxopentanoate + 1 CoA + 1 NAD(+) => 1 3-isovaleryl-CoA + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00860	(S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-isovaleryl-CoA + 1 FAD => 1 3-methylcrotonyl-CoA + 1 FADH2.
http://purl.obolibrary.org/obo/UPa_UER00861	(S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-methylcrotonyl-CoA + 1 ATP + 1 bicarbonate => 1 3-methylglutaconyl-CoA + 1 ADP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00862	(S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-methylglutaconyl-CoA + 1 H(2)O => 1 (S)-3-hydroxy-3-methylglutaryl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00863	acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-3-hydroxy-3-methylglutaryl-CoA => 1 acetoacetate + 1 acetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00864	(1S,4R)-1-hydroxylimonen-2-one from (4R)-limonene: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (4R)-limonene + 1 H(+) + 1 NADH + 1 O(2) => 1 (4R)-limonene 1,2-epoxide + 1 H(2)O + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00865	(1S,4R)-1-hydroxylimonen-2-one from (4R)-limonene: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (4R)-limonene 1,2-epoxide + 1 H(2)O => 1 (1S,2S,4R)-limonene-1,2-diol.
http://purl.obolibrary.org/obo/UPa_UER00866	(1S,4R)-1-hydroxylimonen-2-one from (4R)-limonene: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (1S,2S,4R)-limonene-1,2-diol + 1 NAD(+) => 1 (1S,4R)-1-hydroxylimonen-2-one + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00867	(1R,4S)-isodihydrocarvone from (4R)-limonene: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (4R)-limonene + 1 H(+) + 1 NADPH + 1 O(2) => 1 (4S,6R)-trans-carveol + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00868	(1R,4S)-isodihydrocarvone from (4R)-limonene: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (4S,6R)-trans-carveol + 1 NAD(+) => 1 (S)-carvone + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00869	(1R,4S)-isodihydrocarvone from (4R)-limonene: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-carvone + 1 reduced acceptor => 1 (1R,4S)-isodihydrocarvone + 1 acceptor.
http://purl.obolibrary.org/obo/UPa_UER00870	formaldehyde from methylamine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 amicyanin + 1 methylamine => 2 H(+) + 1 NH(3) + 1 formaldehyde + 1 reduced amicyanin.
http://purl.obolibrary.org/obo/UPa_UER00871	S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 S-methyl-5'-thioadenosine => 1 5-methylthio-alpha-D-ribose + 1 adenine.
http://purl.obolibrary.org/obo/UPa_UER00872	S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-methylthio-alpha-D-ribose + 1 ATP => 1 ADP + 1 S-methyl-5-thio-alpha-D-ribose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00873	S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-methyl-5'-thioadenosine + 1 phosphate => 1 S-methyl-5-thio-alpha-D-ribose 1-phosphate + 1 adenine.
http://purl.obolibrary.org/obo/UPa_UER00874	L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-methyl-5-thio-alpha-D-ribose 1-phosphate => 1 S-methyl-5-thio-D-ribulose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00875	L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 S-methyl-5-thio-D-ribulose 1-phosphate => 1 5-(methylthio)-2,3-dioxopentyl phosphate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER00876	L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-(methylthio)-2,3-dioxopentyl phosphate => 1 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate.
http://purl.obolibrary.org/obo/UPa_UER00877	L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate + 1 H(2)O => 1 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00878	L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 5/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + 1 O(2) => 1 4-methylthio-2-oxobutanoate + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00879	L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 6/6	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-methylthio-2-oxobutanoate + 1 L-glutamate => 1 2-oxoglutarate + 1 L-methionine.
http://purl.obolibrary.org/obo/UPa_UER00880	4-aminobutanoate from putrescine: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-glutamate + 1 putrescine => 1 ADP + 1 gamma-L-glutamylputrescine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00881	4-aminobutanoate from putrescine: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O(2) + 1 gamma-L-glutamylputrescine => 1 H(2)O(2) + 1 NH(3) + 1 gamma-glutamyl-4-aminobutanal.
http://purl.obolibrary.org/obo/UPa_UER00882	4-aminobutanoate from putrescine: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		H(2)O + gamma-glutamyl-4-aminobutanal + [NAD(+) or NADP(+)] => 4-(L-gamma-glutamylamino)butanoic acid + H(+) + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00883	4-aminobutanoate from putrescine: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-(L-gamma-glutamylamino)butanoic acid + 1 H(2)O => 1 4-aminobutanoate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00884	ppGpp from GTP: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 GTP => 1 AMP + 1 guanosine 3'-diphosphate 5'-triphosphate.
http://purl.obolibrary.org/obo/UPa_UER00885	ppGpp from GTP: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 guanosine 3'-diphosphate 5'-triphosphate => 1 phosphate + 1 ppGpp.
http://purl.obolibrary.org/obo/UPa_UER00886	ppGpp from GDP: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GDP + 1 diphosphate => 1 H(2)O + 1 ppGpp.
http://purl.obolibrary.org/obo/UPa_UER00887	GMP from guanine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 guanine => 1 GMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00888	D-ribose 5-phosphate from beta-D-ribopyranose: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 beta-D-ribopyranose => 1 D-ribose.
http://purl.obolibrary.org/obo/UPa_UER00889	D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-ribose => 1 ADP + 1 D-ribose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00890	nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-phospho-alpha-D-ribose 1-diphosphate + 1 nicotinamide => 1 diphosphate + 1 nicotinamide D-ribonucleotide.
http://purl.obolibrary.org/obo/UPa_UER00891	formate from pyruvate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CoA + 1 pyruvate => 1 acetyl-CoA + 1 formate.
http://purl.obolibrary.org/obo/UPa_UER00892	stachyose from raffinose: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1-alpha-D-galactosyl-myo-inositol + 1 raffinose => 1 myo-inositol + 1 stachyose.
http://purl.obolibrary.org/obo/UPa_UER00893	formaldehyde from methanol: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 methanol => 1 H(+) + 1 NADH + 1 formaldehyde.
http://purl.obolibrary.org/obo/UPa_UER00894	acetoacetyl-CoA from succinyl-CoA: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetoacetate + 1 succinyl-CoA => 1 acetoacetyl-CoA + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER00895	L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-serine + 1 tRNA(Sec) => 1 AMP + 1 L-seryl-tRNA(Sec) + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00896	selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-seryl-tRNA(Sec) + 1 selenophosphate => 1 phosphate + 1 selenocysteinyl-tRNA(Sec).
http://purl.obolibrary.org/obo/UPa_UER00897	selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-seryl-tRNA(Sec) => 1 ADP + 1 O-phosphoseryl-tRNA(Sec).
http://purl.obolibrary.org/obo/UPa_UER00898	selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 O-phosphoseryl-tRNA(Sec) + 1 selenophosphate => 2 phosphate + 1 selenocysteinyl-tRNA(Sec).
http://purl.obolibrary.org/obo/UPa_UER00899	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide + 1 L-glutamine => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + 1 D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + 1 L-glutamate.
http://purl.obolibrary.org/obo/UPa_UER00900	1,4-dihydroxy-2-naphthoate from chorismate: step 3/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid => 1 (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00901	acetaldehyde and pyruvate from p-cumate: step 1/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 p-cumate => 1 NAD(+) + 1 cis-2,3-dihydroxy-2,3-dihydro-p-cumic acid.
http://purl.obolibrary.org/obo/UPa_UER00902	acetaldehyde and pyruvate from p-cumate: step 2/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 cis-2,3-dihydroxy-2,3-dihydro-p-cumic acid => 1 2,3-dihydroxy-p-cumic acid + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00903	acetaldehyde and pyruvate from p-cumate: step 3/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2,3-dihydroxy-p-cumic acid + 1 O(2) => 1 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoic acid.
http://purl.obolibrary.org/obo/UPa_UER00904	acetaldehyde and pyruvate from p-cumate: step 4/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoic acid => 1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoic acid + 1 CO(2).
http://purl.obolibrary.org/obo/UPa_UER00905	acetaldehyde and pyruvate from p-cumate: step 5/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoic acid + 1 H(2)O => 1 2-hydroxy-2,4-pentadienoate + 1 2-methylpropanoate.
http://purl.obolibrary.org/obo/UPa_UER00906	acetaldehyde and pyruvate from p-cumate: step 6/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-2,4-pentadienoate + 1 H(2)O => 1 4-hydroxy-2-oxopentanoate.
http://purl.obolibrary.org/obo/UPa_UER00907	acetaldehyde and pyruvate from p-cumate: step 7/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-hydroxy-2-oxopentanoate => 1 acetaldehyde + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER00908	succinyl-CoA from propanoyl-CoA: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 bicarbonate + 1 propanoyl-CoA => 1 (S)-methylmalonyl-CoA + 1 ADP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00909	succinyl-CoA from propanoyl-CoA: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-methylmalonyl-CoA => 1 (R)-methylmalonyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00910	succinyl-CoA from propanoyl-CoA: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (R)-methylmalonyl-CoA => 1 succinyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00911	glycine from 2-phosphoglycolate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-phosphoglycolate + 1 H(2)O => 1 glycolate + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00912	glycine from 2-phosphoglycolate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 O(2) + 1 glycolate => 1 H(2)O(2) + 1 glyoxylate.
http://purl.obolibrary.org/obo/UPa_UER00913	glycine from 2-phosphoglycolate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 glyoxylate => 1 2-oxoglutarate + 1 glycine.
http://purl.obolibrary.org/obo/UPa_UER00914	3-phospho-D-glycerate from glycine: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,10-methylene-THF + 1 H(2)O + 1 glycine => 1 5,6,7,8-tetrahydrofolate + 1 L-serine.
http://purl.obolibrary.org/obo/UPa_UER00915	3-phospho-D-glycerate from glycine: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-serine + 1 pyruvate => 1 3-hydroxypyruvate + 1 L-alanine.
http://purl.obolibrary.org/obo/UPa_UER00916	3-phospho-D-glycerate from glycine: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-hydroxypyruvate + 1 H(+) + 1 NADH => 1 D-glycerate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00917	3-phospho-D-glycerate from glycine: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 D-glycerate => 1 3-phospho-D-glycerate + 1 ADP.
http://purl.obolibrary.org/obo/UPa_UER00918	6-hydroxypseudooxynicotine from nicotine (R-isomer route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 acceptor + 1 nicotine => 1 (R)-6-hydroxynicotine + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER00919	6-hydroxypseudooxynicotine from nicotine (S-isomer route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-6-hydroxynicotine + 1 H(2)O + 1 O(2) => 1 6-hydroxypseudooxynicotine + 1 H(2)O(2).
http://purl.obolibrary.org/obo/UPa_UER00920	acetyl-CoA from myo-inositol: step 4/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-deoxy-D-glucuronic acid => 1 2-deoxy-5-keto-D-gluconic acid.
http://purl.obolibrary.org/obo/UPa_UER00921	2-deoxystreptamine from D-glucose 6-phosphate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucose 6-phosphate => 1 2-deoxy-scyllo-inosose + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00922	2-deoxystreptamine from D-glucose 6-phosphate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-deoxy-scyllo-inosose + 1 L-glutamine => 1 2-deoxy-scyllo-inosamine + 1 2-oxoglutaramate.
http://purl.obolibrary.org/obo/UPa_UER00923	2-deoxystreptamine from D-glucose 6-phosphate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		2-deoxy-scyllo-inosamine + [NAD(+) or NADP(+)] => 3-amino-2,3-dideoxy-scyllo-inosose + H(+) + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER00924	2-deoxystreptamine from D-glucose 6-phosphate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-amino-2,3-dideoxy-scyllo-inosose + 1 L-glutamine => 1 2-deoxystreptamine + 1 2-oxoglutaramate.
http://purl.obolibrary.org/obo/UPa_UER00925	(4S)-limonene from geranyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 geranyl diphosphate => 1 (4S)-limonene + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00926	(4R)-limonene from geranyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 geranyl diphosphate => 1 (4R)-limonene + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00927	(-)-alpha-pinene from geranyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 geranyl diphosphate => 1 (-)-alpha-pinene + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00928	(-)-beta-pinene from geranyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 geranyl diphosphate => 1 (-)-beta-pinene + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00929	FMN from riboflavin (CTP route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CTP + 1 riboflavin => 1 CDP + 1 FMN.
http://purl.obolibrary.org/obo/UPa_UER00930	GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GTP + 1 alpha-D-mannose 1-phosphate => 1 GDP-alpha-D-mannose + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER00931	L-ascorbate from GDP-alpha-D-mannose: step 1/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GDP-alpha-D-mannose => 1 GDP-L-galactose.
http://purl.obolibrary.org/obo/UPa_UER00932	L-ascorbate from GDP-alpha-D-mannose: step 2/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GDP-L-galactose + 1 phosphate => 1 GDP + 1 beta-L-galactose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UER00933	L-ascorbate from GDP-alpha-D-mannose: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 beta-L-galactose 1-phosphate => 1 alpha-L-galactose + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00934	L-ascorbate from GDP-alpha-D-mannose: step 4/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 alpha-L-galactose => 1 H(+) + 1 L-Galactono-1,4-lactone + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00935	L-ascorbate from GDP-alpha-D-mannose: step 5/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-Galactono-1,4-lactone + 2 ferricytochrome c => 2 H(+) + 1 L-ascorbate + 2 ferrocytochrome c.
http://purl.obolibrary.org/obo/UPa_UER00936	L-ascorbate from UDP-alpha-D-glucuronate: step 1/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 UDP-alpha-D-glucuronate => 1 D-glucuronate + 1 UDP.
http://purl.obolibrary.org/obo/UPa_UER00937	L-ascorbate from UDP-alpha-D-glucuronate: step 2/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glucuronate + 1 H(+) + 1 NADPH => 1 L-gulonate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00938	L-ascorbate from UDP-alpha-D-glucuronate: step 3/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-gulonate => 1 H(2)O + 1 L-gulono-1,4-lactone.
http://purl.obolibrary.org/obo/UPa_UER00939	L-ascorbate from UDP-alpha-D-glucuronate: step 4/4	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-gulono-1,4-lactone + 1 O(2) => 1 H(2)O(2) + 1 L-ascorbate.
http://purl.obolibrary.org/obo/UPa_UER00940	phosphatidylcholine from choline: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-diacylglycerol + 1 choline => 1 CMP + 1 phosphatidylcholine.
http://purl.obolibrary.org/obo/UPa_UER00941	putrescine from N-carbamoylputrescine (transferase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 N-carbamoylputrescine + 1 phosphate => 1 carbamoyl phosphate + 1 putrescine.
http://purl.obolibrary.org/obo/UPa_UER00942	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-amino-1-(5-phospho-D-ribosyl)imidazole + 1 ATP + 1 bicarbonate => 1 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + 1 ADP + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER00943	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole => 1 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.
http://purl.obolibrary.org/obo/UPa_UER00944	7,8-diaminononanoate from 8-amino-7-oxononanoate (Lys route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 8-amino-7-oxononanoate + 1 L-lysine => 1 7,8-diaminononanoate + 1 L-2-aminoadipate 6-semialdahyde.
http://purl.obolibrary.org/obo/UPa_UER00945	orotate from (S)-dihydroorotate (NAD(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-dihydroorotate + 1 NAD(+) => 1 H(+) + 1 NADH + 1 orotate.
http://purl.obolibrary.org/obo/UPa_UER00946	orotate from (S)-dihydroorotate (quinone route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-dihydroorotate + 1 Quinone => 1 Hydroquinone + 1 orotate.
http://purl.obolibrary.org/obo/UPa_UER00949	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-aspartate 4-semialdehyde + 1 NADH => 1 L-homoserine + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00950	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-aspartate 4-semialdehyde + 1 NADPH => 1 L-homoserine + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00951	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-oxopropanoate + 1 CoA + 1 NAD(+) => 1 CO(2) + 1 H(+) + 1 NADH + 1 acetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00952	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3-oxopropanoate + 1 CoA + 1 NADP(+) => 1 CO(2) + 1 H(+) + 1 NADPH + 1 acetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00953	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 adenosylcobinamide => 1 ADP + 1 adenosylcobinamide phosphate.
http://purl.obolibrary.org/obo/UPa_UER00954	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 GTP + 1 adenosylcobinamide => 1 GDP + 1 adenosylcobinamide phosphate.
http://purl.obolibrary.org/obo/UPa_UER00955	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3,4-dihydroxybenzoate + 1 H(+) + 1 NADH + 1 O(2) => 1 CO(2) + 1 H(2)O + 1 NAD(+) + 1 benzene-1,2,4-triol.
http://purl.obolibrary.org/obo/UPa_UER00956	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 3,4-dihydroxybenzoate + 1 H(+) + 1 NADPH + 1 O(2) => 1 CO(2) + 1 H(2)O + 1 NADP(+) + 1 benzene-1,2,4-triol.
http://purl.obolibrary.org/obo/UPa_UER00957	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 maleylacetate => 1 3-oxoadipate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00958	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 maleylacetate => 1 3-oxoadipate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00959	L-tyrosine from L-arogenate (NAD(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arogenate + 1 NAD(+) => 1 CO(2) + 1 H(+) + 1 L-tyrosine + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00960	L-tyrosine from L-arogenate (NADP(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-arogenate + 1 NADP(+) => 1 CO(2) + 1 H(+) + 1 L-tyrosine + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00961	(4-hydroxyphenyl)pyruvate from prephenate (NAD(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 prephenate => 1 (4-hydroxyphenyl)pyruvate + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00962	(4-hydroxyphenyl)pyruvate from prephenate (NADP(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NADP(+) + 1 prephenate => 1 (4-hydroxyphenyl)pyruvate + 1 CO(2) + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00963	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate + 1 NAD(+) => 1 H(+) + 1 NADH + 1 iminoaspartate.
http://purl.obolibrary.org/obo/UPa_UER00964	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-aspartate + 1 NADP(+) => 1 H(+) + 1 NADPH + 1 iminoaspartate.
http://purl.obolibrary.org/obo/UPa_UER00967	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-4-dehydro-6-deoxy-D-glucose + 1 H(+) + 1 NADH => 1 CDP-4-dehydro-3,6-dideoxy-D-glucose + 1 H(2)O + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00968	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 CDP-4-dehydro-6-deoxy-D-glucose + 1 H(+) + 1 NADPH => 1 CDP-4-dehydro-3,6-dideoxy-D-glucose + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00969	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-arabinose + 1 NADH => 1 L-arabinitol + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00970	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 L-arabinose + 1 NADPH => 1 L-arabinitol + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00971	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 S-(hydroxymethyl)glutathione => 1 H(+) + 1 NADH + 1 S-formylglutathione.
http://purl.obolibrary.org/obo/UPa_UER00972	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NADP(+) + 1 S-(hydroxymethyl)glutathione => 1 H(+) + 1 NADPH + 1 S-formylglutathione.
http://purl.obolibrary.org/obo/UPa_UER00973	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-3-oxopropanoate + 1 H(+) + 1 NADH => 1 D-glycerate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00974	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-3-oxopropanoate + 1 H(+) + 1 NADPH => 1 D-glycerate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00975	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-ureidoglycolate + 1 NAD(+) => 1 H(+) + 1 NADH + 1 oxalurate.
http://purl.obolibrary.org/obo/UPa_UER00976	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-ureidoglycolate + 1 NADP(+) => 1 H(+) + 1 NADPH + 1 oxalurate.
http://purl.obolibrary.org/obo/UPa_UER00977	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-arabinose + 1 NAD(+) => 1 D-arabinono-1,4-lactone + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00978	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-arabinose + 1 NADP(+) => 1 D-arabinono-1,4-lactone + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00981	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-3-oxosuccinate + 1 H(+) + 1 NADH => 1 CO(2) + 1 D-glycerate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER00982	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxy-3-oxosuccinate + 1 H(+) + 1 NADPH => 1 CO(2) + 1 D-glycerate + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER00983	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glycerate + 1 NAD(+) => 1 3-hydroxypyruvate + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00984	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-glycerate + 1 NADP(+) => 1 3-hydroxypyruvate + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00985	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-2-aminoadipate 6-semialdahyde + 1 NAD(+) => 1 H(+) + 1 L-alpha-aminoadipate + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00986	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 L-2-aminoadipate 6-semialdahyde + 1 NADP(+) => 1 H(+) + 1 L-alpha-aminoadipate + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00987	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NADP(+) + 1 benzaldehyde => 1 H(+) + 1 NADPH + 1 benzoate.
http://purl.obolibrary.org/obo/UPa_UER00988	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 benzaldehyde => 1 H(+) + 1 NADH + 1 benzoate.
http://purl.obolibrary.org/obo/UPa_UER00989	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 gamma-glutamyl-4-aminobutanal => 1 4-(L-gamma-glutamylamino)butanoic acid + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00990	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NADP(+) + 1 gamma-glutamyl-4-aminobutanal => 1 4-(L-gamma-glutamylamino)butanoic acid + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00993	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 dihydrobiopterin => 1 NAD(+) + 1 tetrahydrobiopterin.
http://purl.obolibrary.org/obo/UPa_UER00994	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADPH + 1 dihydrobiopterin => 1 NADP(+) + 1 tetrahydrobiopterin.
http://purl.obolibrary.org/obo/UPa_UER00995	2-oxoglutarate from isocitrate (NADP(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NADP(+) + 1 isocitrate => 1 2-oxoglutarate + 1 CO(2) + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER00996	2-oxoglutarate from isocitrate (NAD(+) route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 NAD(+) + 1 isocitrate => 1 2-oxoglutarate + 1 CO(2) + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER00997	succinyl-CoA from 2-oxoglutarate (dehydrogenase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 CoA + 1 NAD(+) => 1 CO(2) + 1 H(+) + 1 NADH + 1 succinyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00998	succinyl-CoA from 2-oxoglutarate (synthase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate + 1 CoA + 2 oxidized ferredoxin => 1 CO(2) + 2 H(+) + 2 reduced ferredoxin + 1 succinyl-CoA.
http://purl.obolibrary.org/obo/UPa_UER00999	succinate from succinyl-CoA (ligase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ADP + 1 phosphate + 1 succinyl-CoA => 1 ATP + 1 CoA + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER01000	succinate from succinyl-CoA (transferase route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acetoacetate + 1 succinyl-CoA => 1 acetoacetyl-CoA + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER01001	succinate from 2-oxoglutarate (transferase route): step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-oxoglutarate => 1 CO(2) + 1 succinate semialdehyde.
http://purl.obolibrary.org/obo/UPa_UER01002	succinate from 2-oxoglutarate (transferase route): step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		H(2)O + succinate semialdehyde + [NAD(+) or NADP(+)] => H(+) + succinate + [NADH or NADPH].
http://purl.obolibrary.org/obo/UPa_UER01003	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NAD(+) + 1 succinate semialdehyde => 1 H(+) + 1 NADH + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER01004	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NADP(+) + 1 succinate semialdehyde => 1 H(+) + 1 NADPH + 1 succinate.
http://purl.obolibrary.org/obo/UPa_UER01005	fumarate from succinate (bacterial route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 acceptor + 1 succinate => 1 fumarate + 1 reduced acceptor.
http://purl.obolibrary.org/obo/UPa_UER01006	fumarate from succinate (eukaryal route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 Quinone + 1 succinate => 1 Hydroquinone + 1 fumarate.
http://purl.obolibrary.org/obo/UPa_UER01007	(S)-malate from fumarate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 fumarate => 1 (S)-malate.
http://purl.obolibrary.org/obo/UPa_UER01008	oxaloacetate from (S)-malate (quinone route): step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (S)-malate + 1 Quinone => 1 Hydroquinone + 1 oxaloacetate.
http://purl.obolibrary.org/obo/UPa_UER01009	beta-D-fructofuranosyl alpha-D-mannopyranoside from D-fructose 6-phosphate and GDP-alpha-D-mannose: step 1/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 D-fructose 6-phosphate + 1 GDP-alpha-D-mannose => 1 GDP + 1 beta-D-fructofuranosyl alpha-D-mannopyranoside 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UER01010	beta-D-fructofuranosyl alpha-D-mannopyranoside from D-fructose 6-phosphate and GDP-alpha-D-mannose: step 2/2	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 beta-D-fructofuranosyl alpha-D-mannopyranoside 6-phosphate => 1 beta-D-fructofuranosyl alpha-D-mannopyranoside + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER01011	6-hydroxynicotinate from nicotinate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 NADP(+) + 1 nicotinate => 1 6-hydroxynicotinate + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER01012	propanoate and pyruvate from 6-hydroxynicotinate: step 1/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-hydroxynicotinate + 1 reduced ferredoxin => 1 6-hydroxynicotinate + 1 oxidized ferredoxin.
http://purl.obolibrary.org/obo/UPa_UER01013	propanoate and pyruvate from 6-hydroxynicotinate: step 2/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 6-hydroxynicotinate + 2 H(2)O => 1 2-formylglutarate + 1 NH(3).
http://purl.obolibrary.org/obo/UPa_UER01014	propanoate and pyruvate from 6-hydroxynicotinate: step 3/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-formylglutarate + 1 H(+) + 1 NADH => 1 2-hydroxymethylglutarate + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER01015	propanoate and pyruvate from 6-hydroxynicotinate: step 4/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-hydroxymethylglutarate => 1 2-methyleneglutarate + 1 H(2)O.
http://purl.obolibrary.org/obo/UPa_UER01016	propanoate and pyruvate from 6-hydroxynicotinate: step 5/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-methyleneglutarate => 1 2-methylene-3-methylsuccinate.
http://purl.obolibrary.org/obo/UPa_UER01017	propanoate and pyruvate from 6-hydroxynicotinate: step 6/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-methylene-3-methylsuccinate => 1 dimethylmaleate.
http://purl.obolibrary.org/obo/UPa_UER01018	propanoate and pyruvate from 6-hydroxynicotinate: step 7/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 dimethylmaleate => 1 (2R,3S)-2,3-dimethylmalate.
http://purl.obolibrary.org/obo/UPa_UER01019	propanoate and pyruvate from 6-hydroxynicotinate: step 8/8	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2R,3S)-2,3-dimethylmalate => 1 propanoate + 1 pyruvate.
http://purl.obolibrary.org/obo/UPa_UER01020	4-hydroxybenzoate from 4-chlorobenzoate: step 1/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-chlorobenzoate + 1 ATP + 1 CoA => 1 4-chlorobenzoyl-CoA + 1 AMP + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER01021	4-hydroxybenzoate from 4-chlorobenzoate: step 2/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-chlorobenzoyl-CoA + 1 H(2)O => 1 4-hydroxybenzoyl-CoA + 1 H(+) + 1 chloride.
http://purl.obolibrary.org/obo/UPa_UER01022	4-hydroxybenzoate from 4-chlorobenzoate: step 3/3	http://purl.obolibrary.org/obo/BFO_0000015	process		1 4-hydroxybenzoyl-CoA + 1 H(2)O => 1 4-hydroxybenzoate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UER01023	glycine from L-serine: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 5,6,7,8-tetrahydrofolate + 1 L-serine => 1 5,10-methylene-THF + 1 H(2)O + 1 glycine.
http://purl.obolibrary.org/obo/UPa_UER01024	L-aspartate from oxaloacetate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 L-glutamate + 1 oxaloacetate => 1 2-oxoglutarate + 1 L-aspartate.
http://purl.obolibrary.org/obo/UPa_UER01025	L-glutamine from L-glutamate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 ATP + 1 L-glutamate + 1 NH(3) => 1 ADP + 1 L-glutamine + 1 phosphate.
http://purl.obolibrary.org/obo/UPa_UER01026	catechol from anthranilate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(+) + 1 NADH + 1 O(2) + 1 anthranilate => 1 CO(2) + 1 NAD(+) + 1 NH(3) + 1 catechol.
http://purl.obolibrary.org/obo/UPa_UER01027	L-alpha-aminoadipate from 2-oxoglutarate: step 3/5	http://purl.obolibrary.org/obo/BFO_0000015	process		1 H(2)O + 1 homo-cis-aconitate => 1 homoisocitrate.
http://purl.obolibrary.org/obo/UPa_UER01028	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + 1 H(+) + 1 NADH => 1 (S)-tetrahydrodipicolinate + 1 H(2)O + 1 NAD(+).
http://purl.obolibrary.org/obo/UPa_UER01029	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + 1 H(+) + 1 NADPH => 1 (S)-tetrahydrodipicolinate + 1 H(2)O + 1 NADP(+).
http://purl.obolibrary.org/obo/UPa_UER01030	15-cis-phytoene from geranylgeranyl diphosphate: step 1/1	http://purl.obolibrary.org/obo/BFO_0000015	process		2 geranylgeranyl diphosphate => 1 15-cis-phytoene + 1 diphosphate.
http://purl.obolibrary.org/obo/UPa_UER01031	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-deoxy-scyllo-inosamine + 1 NAD(+) => 1 3-amino-2,3-dideoxy-scyllo-inosose + 1 H(+) + 1 NADH.
http://purl.obolibrary.org/obo/UPa_UER01032	None	http://purl.obolibrary.org/obo/BFO_0000015	process		1 2-deoxy-scyllo-inosamine + 1 NADP(+) => 1 3-amino-2,3-dideoxy-scyllo-inosose + 1 H(+) + 1 NADPH.
http://purl.obolibrary.org/obo/UPa_UER01033	1,4-dihydroxy-2-naphthoate from chorismate: step 7/7	http://purl.obolibrary.org/obo/BFO_0000015	process		1 1,4-dihydroxy-2-naphthoyl-CoA + 1 H(2)O => 1 1,4-dihydroxy-2-naphthoate + 1 CoA.
http://purl.obolibrary.org/obo/UPa_UPA00002	2-deoxy-D-ribose 1-phosphate degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		This pathway provides a direct metabolic link between the deoxyribose moiety of nucleosides and central carbon metabolism, independent of the pentose phosphate cycle. Two enzymes provide this link: the phosphopentomutases (PPMs) and 2-deoxyribose 5-phosphate aldolases (DERAs). PPM isomerizes deoxyribose 1-phosphate to deoxyribose 5-phosphate. Subsequently, DERA cleaves the pentose phosphate to acetaldehyde and glyceraldehyde 3-phosphate, allowing further metabolism to obtain carbon and energy. The deoxyribose 1-phosphate is supplied by various nucleoside phosphorylases, such as thymidine phosphorylase, uridine phosphorylase and purine nucleoside phosphorylase, which release the pentose moiety from (deoxy)ribonucleosides, producing (deoxy)ribose 1-phosphate.
http://purl.obolibrary.org/obo/UPa_UPA00008	atrazine degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of atrazine (2-chloro-4-(ethylamino)-6-(isopropylamino)-1,3,5-triazine), a chlorinated compound used throughout industry and agriculture. Degradation contaminates soils and persists until it is metabolized by microorganisms. A range of soil bacteria, including both Gram-negative and Gram-positive strains can degrade atrazine, utilizing it as a nitrogen and carbon source.
http://purl.obolibrary.org/obo/UPa_UPA00010	1,3-diaminopropane biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis		Biosynthesis of polyamine 1,3-diaminopropane (trimethylenediamine, 1,3-propanediamine, DAP).
http://purl.obolibrary.org/obo/UPa_UPA00012	taurine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00962	L-cysteine metabolism		Biosynthesis of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats. Taurine is a derivative of the sulphur-containing (sulfhydryl) amino acid cysteine. Taurine is abundant in the tissues of many animals (metazoa). It is also found in plants, fungi, and some bacterial species, but at lower levels.
http://purl.obolibrary.org/obo/UPa_UPA00028	(R)-pantothenate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of (R)-pantothenate, also called vitamin B5 or D-pantothenic acid. (R)-pantothenate results from the condensation of beta-alanine and D-pantoate. (R)-pantothenate is found in the 4'-phosphopantetheine moieties of CoA (coenzyme A) and of the acyl carrier protein of lipid synthesis. Micro- organisms and plants must synthesize pantothenate, while animals obtain this essential nutriment from their diet. Pantothenate biosynthesis pathway offers targets for developping drugs against microbial pathogen.
http://purl.obolibrary.org/obo/UPa_UPA00029	staphyloxanthin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis		Biosynthesis of staphyloxanthin. Staphyloxanthin is an orange membrane-bound carotenoid pigment produced by most Staphylococcus aureus strains. It is well known that carotenoids function as antioxidants, and it has been suggested that staphyloxanthin can protect Staphylococcus aureus against oxidative stress.
http://purl.obolibrary.org/obo/UPa_UPA00031	L-histidine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00490	histidine metabolism		Biosynthesis of L-histidine, (S)-alpha-Amino- 1H-imidazole-4-propionic acid, a weakly basic amino-acid in a nine- step pathway. Histidine biosynthetic pathway is present in microbes, fungi and plants. Histidine biosynthesis is unusual as a metabolic process utilizing the purine ring of ATP as a carbon and nitrogen source. Histidine biosynthesis pathway is connected to de novo purine biosynthesis pathway through imidazole glycerol phosphate synthase (IGPS) which catalyzes the fifth step and converts N-(5'-phosphoribulosys)-formimino-5-aminoimidazole-4-carboxamide ribonucleotide (PRFAR) to imidazole glycerol phosphate (ImGP) and 5'-(5-aminoimidazole-4-carboxamide) ribonucleotide (AICAR). AICAR is the entry point to the purine biosynthetic pathway.
http://purl.obolibrary.org/obo/UPa_UPA00032	UDP-4-deoxy-4-formamido-beta-L-arabinose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of UDP-beta-(4-deoxy-4-formamido-L-arabinose) (UDP-L-Ara4FN), a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). This latter compound is covalently linked to lipid A moiety of some pathogenic Gram-negative bacteria. This LPS modification is a strategy adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.
http://purl.obolibrary.org/obo/UPa_UPA00033	L-lysine biosynthesis via AAA pathway	http://purl.obolibrary.org/obo/UPa_UPA00404	L-lysine biosynthesis		Biosynthesis of L-lysine through the alpha-amino adipic acid (AAA) pathway. It was first believed that this pathway was a specific character of fungi. In 1998, a gene cluster of a thermophilic bacterium (Thermus thermophilus) was shown to synthesize L-lysine through the AAA pathway. This pathway is present in hyperthermophilic archaea too (P. horikoshii and P. abyssi). Hence, this pathway is distributed among the three super-kingdoms as proposed by Woese and Fox in 1997 [PMID:270744].
http://purl.obolibrary.org/obo/UPa_UPA00034	L-lysine biosynthesis via DAP pathway	http://purl.obolibrary.org/obo/UPa_UPA00404	L-lysine biosynthesis		Biosynthesis of L-lysine through the diaminopimelate (DAP) pathway. <br> The L-lysine is synthesized from L-aspartate and pyruvate through diaminopimelate via four variants. <br> This pathway is utilised by most bacteria, some archaea, some fungi, some algae, and higher plants.<br> In bacteria, DAP is not only a direct precursor of lysine, but it is also an important constituent of the cell wall peptidoglycan. <br> The DAP pathway is of special interest for pharmacology, since the absence of DAP in mammalian cells allows for the use of the DAP biosynthetic genes as a bacteria-specific drug target. <br> Most bacteria use only one of the four variants, although certain bacteria, such as <i>C. glutamicum </i> and <i>Bacillus macerans</i>, possess both the succinylase and dehydrogenase pathways.
http://purl.obolibrary.org/obo/UPa_UPA00035	L-tryptophan biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00525	aromatic amino-acid biosynthesis		Biosynthesis of the aromatic amino-acid L-tryptophan (Trp) from chorismate. This pathway is present in bacteria, fungi and plants. L-tryptophan is needed to synthesize proteins and, as a precursor, to nicotinic acid (niacin), serotonin and melatonin.
http://purl.obolibrary.org/obo/UPa_UPA00036	4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of undecaprenyl phosphate-4-deoxy-4-formamido-L-arabinose, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N). This latter compound is covalently linked to lipid A moiety of some pathogenic Gram-negative bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00038	UDP-alpha-D-glucuronate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of UDP-glucuronic acid (UDP-GlcUA), a precursor of glycosaminoglycan and proteoglycan synthesis. UDP-GlcUA is also a precursor of ascorbic acid.
http://purl.obolibrary.org/obo/UPa_UPA00041	D-glycero-D-manno-heptose 7-phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Biosynthesis of D-glycero-D-manno-heptose 5-phosphate. This carbohydrate is widely present in the lipopolysaccharide (LPS) of most Gram-negative bacteria. D-glycero-D-manno-heptose and its derivatives are sometimes also found in capsules and O antigen as well as in the glycan moieties of bacterial cell surface (S-layer) glycoproteins. D-glycero-D-manno-heptose are found in different anomeric configuration (alpha and beta).
http://purl.obolibrary.org/obo/UPa_UPA00042	D-alanine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00489	alanine metabolism		Biosynthesis of D-alanine. D-alanine is used either as an energy source or as a component of bacterial cell wall, where it is directly involved in the cross-linking of adjacent peptidoglycan chains. In Gram-positive bacteria, D-alanine can also be found to variable extents in cell wall teichoic acid and lipoteichoic acid residues.
http://purl.obolibrary.org/obo/UPa_UPA00043	D-alanine degradation	http://purl.obolibrary.org/obo/UPa_UPA00489	alanine metabolism		Degradation of D-alanine, the dextrorotatory isomer of the amino-acid alanine.
http://purl.obolibrary.org/obo/UPa_UPA00044	L-threonine degradation via aldolase pathway	http://purl.obolibrary.org/obo/UPa_UPA00493	L-threonine degradation		Degradation of L-threonine via aldolase pathway. L-threonine aldolase is a low-specificity enzyme which cleaves threonine directly into glycine and acetaldehyde .
http://purl.obolibrary.org/obo/UPa_UPA00046	L-threonine degradation via oxydo-reductase pathway	http://purl.obolibrary.org/obo/UPa_UPA00493	L-threonine degradation		Degradation of L-threonine via oxydo-reductase pathway. This pathway involves threonine dehydrogenase (TDH) and 2-amino-3-ketobutyrate CoA ligase (KBL). In the absence of KBL, 2-amino-3-oxobutanoate is spontaneously converted to aminoacetone.
http://purl.obolibrary.org/obo/UPa_UPA00047	L-isoleucine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, an hydrophobic branched- chain amino-acid. In most microorganisms, isoleucine is synthesized from aspartate via threonine [Umbarger, H. E. 1978. Amino-acid biosynthesis and its regulation. Annu. Rev. Biochem. 47:533-606]. However, alternative routes to isoleucine from precursors other than threonine have been reported. Some anaerobes can assimilate 2-methylbutyrate into isoleucine. The most commonly observed alternative route was a route from pyruvate and acetyl coenzyme A (acetyl-CoA) via citramalate. This 'pyruvate pathway' was initially proposed for the genus Leptospira because isotope-labeling experiments indicated that in some leptospiral strains, {alpha}-ketobutyrate was derived from pyruvate rather than threonine. Only a limited number of leptospires possess catabolic threonine dehydratase. Later, a similar observation was made with a thermophilic archaeon, Methanobacterium thermoautotrophicum, suggesting that isoleucine biosynthesis involves pyruvate as a precursor. Recently, (R)-citramalate synthase (EC 4.1.3.-) activity was demonstrated in the thermophilic archaeon Methanococcus jannaschii.
http://purl.obolibrary.org/obo/UPa_UPA00048	L-leucine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-leucine, 2-amino-4-methylpentanoic acid, an hydrophobic branched-chain amino- acid.
http://purl.obolibrary.org/obo/UPa_UPA00049	L-valine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-valine, 2-amino-3-methylbutanoic acid, an hydrophobic branched-chain amino- acid.
http://purl.obolibrary.org/obo/UPa_UPA00050	L-threonine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
http://purl.obolibrary.org/obo/UPa_UPA00051	L-methionine biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00903	L-methionine biosynthesis		Sulfur-containing amino-acid L-methionine (2-amino-4-(methylthio)butanoic acid) is synthesized de novo by most microorganisms and plants after the initial steps of inorganic sulfate assimilation and synthesis of cysteine or homocysteine. There are two alternative pathways of methionine synthesis in microorganisms. The enterobacterial type trans-sulfuration pathway involves cystathionine as an intermediate and utilizes cysteine as the sulfur source. In contrast, the direct sulfhydrylation pathway found in yeast (Saccharomyces cerevisiae), spirochete (Leptospira meyeri) and actinomycetes (Corynebacterium glutamicum) bypasses cystathionine and uses inorganic sulfur instead. Although yeast, fungi and higher plants have both transsulfuration and direct sulfhydrylation pathways, only the bacteria C. glutamicum, B. subtilis, P. aeruginosa, P. putida and L. meyeri have been shown to have both pathways. Methionine biosynthesis is a central pathway, as it controls a large number of cellular processes such as translation of mRNA into proteins (not only as a substrate for protein elongation but also as the initiator of protein synthesis) and transmethylation reactions via the formation of S-adenosylmethionine (SAM) (cf activated methyl cycle pathway).
http://purl.obolibrary.org/obo/UPa_UPA00052	L-threonine degradation via propanoate pathway	http://purl.obolibrary.org/obo/UPa_UPA00493	L-threonine degradation		Degradation of L-threonine via propanoate pathway. L-threonine can be catabolized non-oxidatively to propionate via 2-ketobutyrate.
http://purl.obolibrary.org/obo/UPa_UPA00053	chorismate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of chorismate, a precursor of aromatic amino-acids (tryptophan, tyrosine and phenylalanine). The biosynthesis of chorismate occurs only in plants and bacterial, not in animals.
http://purl.obolibrary.org/obo/UPa_UPA00055	CDP-3,6-dideoxy-D-mannose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of CDP-3,6-dideoxy-D-mannose (CDP-tyvelose), a 3,6-dideoxy nucleotide sugar. CDP-3,6-dideoxy-D-mannose is a cell wall lipopolysaccharide O-antigen component of some Gram-negative bacteria.
http://purl.obolibrary.org/obo/UPa_UPA00056	isopentenyl diphosphate biosynthesis via DXP pathway	http://purl.obolibrary.org/obo/UPa_UPA00417	isopentenyl diphosphate biosynthesis		Biosynthesis of isopentenyl-PP via deoxy xylulose phosphate (DXP) pathway. This pathway is essential in eubacteria (including Escherichia coli), the malaria parasite, and plants, but is absent in mammals. Therefore, the pathway enzymes are promising targets for the development of novel herbicides and antimicrobials that are potentially innocuous for humans.
http://purl.obolibrary.org/obo/UPa_UPA00057	isopentenyl diphosphate biosynthesis via mevalonate pathway	http://purl.obolibrary.org/obo/UPa_UPA00417	isopentenyl diphosphate biosynthesis		Biosynthesis of isopentenyl-PP (isopentenyl diphosphate, IDP, IPP) via mevalonic acid pathway. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl-PP, the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
http://purl.obolibrary.org/obo/UPa_UPA00058	(R)-mevalonate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00497	(R)-mevalonate metabolism		Biosynthesis of mevalonic acid, a six-carbon metabolic intermediate. In eukaryotes, it arises from linkage of two acetyl-CoAs in the mitochondrion to form acetaoacetyl-CoA (4 carbons), followed by addition of another acetyl group from a third acetyl-CoA to give 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA). This latter compound is reduced by HMG-CoA reductase in the endoplasmic reticulum, using two NADPHs, with coincident loss of CoASH. HMG-CoA reductase is the most important regulatory enzyme for the cholesterol biosynthetic pathway and other isoprenoids/terpenoids. HMG-CoA reductase is a target for drugs that attempt to lower cholesterol levels in the body. One such drug is lovastatin, which inhibits the enzyme and stops endogenous synthesis of cholesterol.
http://purl.obolibrary.org/obo/UPa_UPA00059	dimethylallyl diphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00416	isoprenoid biosynthesis		Biosynthesis of dimethylallyl-PP (DMAPP). DMAPP results from the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl-PP (IPP).
http://purl.obolibrary.org/obo/UPa_UPA00060	thiamine diphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00840	thiamine metabolism		Biosynthesis of thiamin pyrophosphate (THI-PP, TPP), the active form of thiamine cofactor (vitamin B1). It has essential functions, for example in carbohydrate and branched-chain amino-acid metabolism. All organisms able to to produce THI-PP initially assemble THI-P by coupling 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole. THI-P is then converted to TPP. The two heterocyclic precursors of thiamine pyrophosphate are synthesized through independant pathways. WARNING: the DXP_MHETP_BIOS sub-pathway is temporary. It will be refined as soon as knowledge will be available.
http://purl.obolibrary.org/obo/UPa_UPA00061	alpha-ribazole biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00425	nucleoside biosynthesis		Biosynthesis of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).
http://purl.obolibrary.org/obo/UPa_UPA00064	1-deoxy-D-xylulose 5-phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.
http://purl.obolibrary.org/obo/UPa_UPA00067	ectoine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis		Biosynthesis of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid), an excellent osmoprotectant. Since Galinski et al. (PMID:3838936) discovered ectoine as a compatible solute in Ectothiorhodospira halochloris, an extremely halophilic phototrophic eubacterium, it has been found to be distributed widely in nature, largely in moderately halophilic eubacteria. The biosynthetic pathway of ectoine from aspartic b-semialdehyde (ASA) was first elucidated in Halomonas elongata by purification and characterization of each enzyme involved.
http://purl.obolibrary.org/obo/UPa_UPA00068	L-arginine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00429	L-arginine metabolism		Biosynthesis of L-arginine, an amino-acid constituent of proteins and precursor of polyamines.
http://purl.obolibrary.org/obo/UPa_UPA00074	IMP biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00648	IMP biosynthesis		The formation from simpler components of purine nucleotide IMP (inosine 5'phosphate).
http://purl.obolibrary.org/obo/UPa_UPA00075	AMP biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00593	purine biosynthesis via de novo pathway		The formation of AMP (adenosine monophosphate) from IMP (inosine monophosphate).
http://purl.obolibrary.org/obo/UPa_UPA00076	myo-inositol degradation into acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UPA00405	myo-inositol degradation		Degradation of myo-inositol, an abundant compound in soil. Myo-Inositol is also common and essential in plants. Several micro-organisms, including model organism Bacillus subtilis (PMID:9226270), can grow on inositol as the carbon source. It was thought that bacterial inositol catabolism is only required for efficient utilization of this compound. However, the inositol dehydrogenase of Sinorhizobium fredii not only catalyses the initial reaction step of inositol catabolism but also is involved in nitrogen fixation and competitiveness to nodulate soybeans (PMID:11274120). Furthermore, MocA and MocC of Sinorhizobium meliloti which participate in degradation of rhizopine (L-3-O-methyl-scyllo-inosamine), a symbiosis- specific compound found in alfalfa nodules, exhibited significant similarities to IolG and IolE involved in inositol catabolism of B. subtilis, respectively (PMID:9226270), and the inositol catabolism pathway was tightly linked with rhizopine utilization in S. meliloti (PMID:9802033). These facts implied an interesting relationship between bacterial inositol catabolism and plant/bacteria symbiosis for nitrogen fixation.
http://purl.obolibrary.org/obo/UPa_UPA00077	tetrahydrofolate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA01000	tetrahydrofolate metabolism		Biosynthesis of tetrahydrofolic acid (tetrahydrofolate, THF), the active form of folic acid (vitamin B9). Folic acid is an essential vitamin (B9), which plays a key role in the methylation cycle and in DNA biosynthesis. The folic acid derivatives are made up of a pterdine ring attached to a p-aminobenzoate and a polyglutamyl chain. Tetrahydrofolic acid have C1 units enzymically attached. These C1 units (as a formyl group) are passed on to enzymes in the purine pathway that insert the C-2 and C-8 into the purine ring. A methylene group (-CH2-) attached to tetrahydrofolate is used to convert the uracil-type pyrimidine base found in RNA into the thymine base found in DNA. A further folate cofactor, i.e. 5-methyltetrahydrofolate, is involved in the remethylation of the homocysteine produced in the methylation cycle back to methionine. After activation to S-adenosylmethionine this acts as a methyl donor for the dozens of different methyltransferases present in all cells. Folate deficiency results in reduction of purine and pyrimidine biosynthesis and consequently DNA biosynthesis and cell division. Folate deficiency receives increasing attention due to its relation to cardiovascular disease and different forms of dementia. The folate pathway represents a powerful target for combating rapidly dividing systems such as cancer cells, bacteria and malaria parasites.
http://purl.obolibrary.org/obo/UPa_UPA00078	biotin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of biotin, a B-group vitamin. Biotin has essential metabolic functions as the CO2-carrying prosthetic group of selected carboxylases, decarboxylases and transcarboxylases. De novo biosynthesis pathway involved the conversion of pimeloyl-CoA (i.e 6-carboxyhexanoyl-CoA) to biotin.
http://purl.obolibrary.org/obo/UPa_UPA00081	D-galactonate degradation	http://purl.obolibrary.org/obo/UPa_UPA00858	carbohydrate acid degradation		Degradation of D-galactonic acid.
http://purl.obolibrary.org/obo/UPa_UPA00084	phosphatidylglycerol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00751	phospholipid biosynthesis		Biosynthesis of phosphatidylglycerol, a multifunctional phospholipid, found in the biological membranes of many organisms.
http://purl.obolibrary.org/obo/UPa_UPA00087	5-phospho-alpha-D-ribose 1-diphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis (PRPP). PRPP may be synthesized from ribose 5-phosphate by PRPP synthase or, alternately, by the the enzymes phosphopentomutase, ribose 1-phosphokinase (putative), and ribose 1,5-bisphosphokinase [PMID:12700258]. Under conditions when xanthosine phosphorylase is produced, the enzyme can supply ribose 1-phosphate to this second pathway.
http://purl.obolibrary.org/obo/UPa_UPA00088	3,4-dihydroxybenzoate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Biosynthesis of 3,4-dihydroxybenzoate (protocatechuate). This pathway allows use of quinate as a carbon source by its conversion to protocatechuate and subsequent metabolism by the beta-ketoadipate pathway. Quinate is an abundant plant product.
http://purl.obolibrary.org/obo/UPa_UPA00098	L-proline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00531	L-proline metabolism		Biosynthesis of L-proline (pyrrolidine-2-carboxylic acid) biosynthesis, a chiral, cyclic amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00104	creatine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis		Biosynthesis of creatine, a nitrogenous organic acid. Creatine (Cr) is synthesized by a two-step mechanism involving arginine:glycine amidinotransferase (AGAT) and guanidinoacetate methyltransferase (GAMT), and is taken up by cells through a specific Cr transporter, CT1 [PMID:15918910].
http://purl.obolibrary.org/obo/UPa_UPA00106	nicotine degradation	http://purl.obolibrary.org/obo/UPa_UPA00447	alkaloid degradation		Degradation of nicotine, the primary alkaloid found in tobacco plants.
http://purl.obolibrary.org/obo/UPa_UPA00109	glycolysis	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Glycolysis is a metabolic pathway found in all organisms. This pathway results in the anaerobic enzymatic conversion of D-glucose to pyruvate, resulting in energy stored in the form of adenosine triphosphate (ATP).
http://purl.obolibrary.org/obo/UPa_UPA00111	myo-inositol degradation into D-glucuronate	http://purl.obolibrary.org/obo/UPa_UPA00405	myo-inositol degradation		Irreversible degradation of myo-inositol into D-glucuronic acid.
http://purl.obolibrary.org/obo/UPa_UPA00112	clavulanate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00169	beta-lactam biosynthesis		Biosynthesis of clavulanic acid, a beta-lactam, structurally related to the penicillins, that possesses the ability to inactivate a wide range of beta-lactamase enzymes commonly found in microorganisms resistant to penicillins and cephalosporins. The name clavulanic acid is derived from the Streptomyces clavuligerus microorganisms from which clavulanic acid is derived. Clavulanic acid is biosynthetically generated from the amino-acid L-arginine and from pyruvate.
http://purl.obolibrary.org/obo/UPa_UPA00113	UDP-N-acetyl-alpha-D-glucosamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of UDP-N-acetylglucosamine.
http://purl.obolibrary.org/obo/UPa_UPA00115	pentose phosphate pathway	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		The pentose phosphate pathway is part of central metabolism. This pathway provides a means by which glucose can be oxidized to generate NADPH and is the source of much of the NADPH that is needed for the biosynthesis of many biomolecules. The pentose phosphate pathway and the Calvin cycle have in common several enzymes and intermediates that attest to a common evolution. Like glycolysis and gluconeogenesis, these pathways are mirror images of one another: the Calvin cycle uses NADPH to reduce carbon dioxide to generate hexoses, whereas the pentose phosphate pathway breaks down glucose into carbon dioxide to generate NADPH. The Calvin cycle is sometimes referred to as the reductive pentose phosphate pathway [Stryer, Biochemistry, 2002]. For convenience, the pentose phosphate pathway is commonly divided into its preliminary oxidative stage in which glucose-6-phosphate is oxidized to ribulose-5-phosphate, and its subsequent non-oxidative stage, in which through a series of transaldolase and transketolase reactions, ribulose-5-phosphate is converted into fructose-6-phosphate and glyceraldehyde-3-phosphate.
http://purl.obolibrary.org/obo/UPa_UPA00120	prephenate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of prephenate from chorismate. Prephenate is an intermediate in the biosynthesis of aromatic amino-acids, L-Phenylalanine and L-Tyrosine.
http://purl.obolibrary.org/obo/UPa_UPA00121	L-phenylalanine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00525	aromatic amino-acid biosynthesis		Biosynthesis of L-phenylalanine ((S)-alpha-amino-beta-phenylpropionic acid) from prephenate.
http://purl.obolibrary.org/obo/UPa_UPA00122	L-tyrosine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00525	aromatic amino-acid biosynthesis		Biosynthesis of L-tyrosine ((S)-3-(p-hydroxyphenyl)alanine) from prephenate.
http://purl.obolibrary.org/obo/UPa_UPA00126	GDP-alpha-D-mannose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		The formation from simpler components of GDP-D-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
http://purl.obolibrary.org/obo/UPa_UPA00128	GDP-L-fucose biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00453	GDP-L-fucose biosynthesis		Biosynthesis of GDP-L-fucose via de novo pathway. GDP-L-fucose, the substrate for fucosyltransferases for addition of fucose to polysaccharides or glycoproteins in both procaryotes and eucaryotes, is made from GDP-D-mannose. L-Fucose is a component of bacterial surface antigens, including the extracellular polysaccharide colanic acid produced by most Escherichia coli strains, as well as by other species of the family Enterobacteriaceae. In the de novo pathway, GDP-L-fucose is synthesized from GDP-mannose via an oxidation, an epimerization, and a reduction. These steps are catalyzed by two enzymes, GDP-mannose-4,6-dehydratase and GDP-4-keto-6 -deoxy-mannose-3,5-epimerase-4-reductase (FX in mammals). In mammals, the de novo pathway is the major route for cellular GDP-L-fucose biosynthesis in vivo. Levels of GDP-L-fucose in human hepatocellular carcinoma tissues are significantly increased compared with adjacent nontumor tissues or normal livers. (relationship between elevated FX expression and increased production of GDP-L-Fucose).
http://purl.obolibrary.org/obo/UPa_UPA00130	2-(alpha-D-mannosyl)-D-glycerate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Biosynthesis of alpha mannosylglycerate (MG), a compatible solute originally identified in red algae of the order Ceramiales. Mannosylglycerate is a common compatible solute of halotolerant or slightly halophilic thermophilic and hyperthermophilic prokaryotes. Mannosylglycerate has a role in stabilizing proteins from thermal denaturation, since it is one of the most efficient thermoprotectants known in vitro. The biosynthesis of MG proceeds via two alternate routes. In one pathway, GDP-mannose is condensed with D-glycerate to produce MG in a single glycosyl transfer reaction catalyzed by MG synthase. In the other pathway, mannosyl-3-phosphoglycerate synthase (MPGS) catalyzes the conversion of GDP-mannose and D-3-phosphoglycerate into mannosyl-3-phosphoglycerate (MPG), which is subsequently converted to MG by mannosyl-3-phosphoglycerate phosphatase (MPGP).
http://purl.obolibrary.org/obo/UPa_UPA00134	L-asparagine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-asparagine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00135	L-serine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of L-serine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00136	L-cysteine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00962	L-cysteine metabolism		Biosynthesis of L-cysteine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00139	L-phenylalanine degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of L-phenylalanine, an aromatic amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00140	hydrogen sulfide biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00096	sulfur metabolism		Conversion of sulfate to hydrogen sulfide, in preparation for incorporation into cysteine and methionine. Sulfate can provide sulfur for biosynthesis. The sulfur atom in sulfate is more oxidized than it is in cysteine and other organic molecules; thus sulfate must be reduced before it can be assimilated. This process is known as assimilatory sulfate reduction to distinguish it from the dissimilatory sulfate reduction that takes place when sulfate acts as an electron acceptor during anaerobic respiration.
http://purl.obolibrary.org/obo/UPa_UPA00141	L-arabinose degradation via L-arabinono-1,4-lactone pathway	http://purl.obolibrary.org/obo/UPa_UPA00463	L-arabinose degradation		Degradation of L-arabinose via L-arabinono-1,4-lactone pathway. In this catabolic pathway, L-arabinose is oxidized to L-arabino-gamma-lactone (L-arabinono-1,4-lactone) by a NAD(P)+-dependent dehydrogenase. The lactone is cleaved by a lactonase to L-arabonate, followed by two successive dehydration reactions forming L-2-keto-3-deoxyarabonate (L-KDA)2 and alpha-ketoglutaric semialdehyde(alpha-KGSA). The last step is the NAD(P)+-dependent dehydrogenation of alpha-KGSA to alpha-ketoglutaric acid (referred to as the first pathway). Alternatively, L-KDA is cleaved through an aldolase reaction to glycolaldehyde and pyruvate (referred to as the second pathway).
http://purl.obolibrary.org/obo/UPa_UPA00142	glutathione biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00454	oligopeptide biosynthesis		Biosynthesis of glutathione (GSH; L-{gamma}-glutamyl-L-cysteinylglycine), a predominant low molecular weight peptide thiol present in many Gram- negative bacteria and in virtually all eukaryotes, except those that lack mitochondria.
http://purl.obolibrary.org/obo/UPa_UPA00145	L-arabinose degradation via L-ribulose	http://purl.obolibrary.org/obo/UPa_UPA00463	L-arabinose degradation		Degradation of L-arabinose via L-ribulose pathway. The bacterial L-arabinose catabolic pathway consists of L-arabinose isomerase (EC 5.3.1.4), ribulokinase (EC 2.7.1.16), and L-ribulose phosphate 4-epimerase (EC 5.1.3.4) which convert L-arabinose to D-xylulose 5-phosphate. The pathway and the genes of this pathway are well-established.
http://purl.obolibrary.org/obo/UPa_UPA00146	L-arabinose degradation via L-arabinitol	http://purl.obolibrary.org/obo/UPa_UPA00463	L-arabinose degradation		Degradation of L-arabinose via L-arabinitol pathway. The fungal L-arabinose catabolic pathway consists of aldose reductase (EC 1.1.1.21), L-arabinitol 4-dehydrogenase (EC 1.1.1.12), L-xylulose reductase (EC 1.1.1.10), D-xylulose reductase (EC 1.1.1.9), and xylulokinase (EC 2.7.1.17) which convert L-arabinose to D-xylulose 5-phosphate.
http://purl.obolibrary.org/obo/UPa_UPA00148	adenosylcobalamin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of adenosylcobalamin (vitamin B12), a modified tetrapyrrole cofactor. Adenosylcobalamin belongs to the same class of compounds as heme, chlorophyll, siroheme, and coenzyme F430. Most prokaryotic organisms as well as animals (including human) and protists have enzyme that require adenosylcobalamin as cofactor, whereas plants and fungi are thought not to use it. It is one of the most structurally complex protein cofactors ans its biosynthesis remains one of the most enigmatic and exigent metabolic pathways in nature, requiring around 30 enzymes. Two distinct yet similar route exist, known as the oxygene-dependent (aerobic route) and oxygen-independent (anaerobic route) pathways. These pathways diverge at precorrin-2 and merge again at adenosylcobyrate. The major difference between these two routes include the timing of cobalt insertion, the requirement for oxygen and the nature of the extruded carbon fragment which is lost during the ring construction process [McGoldrick et al, 2005].
http://purl.obolibrary.org/obo/UPa_UPA00149	penicillin G biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00474	penicillin biosynthesis		Biosynthesis of penicillin G, a beta-lactam antibiotic. Penicillin G is one of the mainly used antibiotics for the therapy of infectious diseases. It is produced as end product by some filamentous fungi only, most notably by Aspergillus (Emericella) nidulans and Penicillium chrysogenum. The penicillin biosynthesis is catalysed by three enzymes which are encoded by the following three genes: pcbAB (acvA), pcbC (ipnA) and penDE (aatA).
http://purl.obolibrary.org/obo/UPa_UPA00155	biphenyl degradation	http://purl.obolibrary.org/obo/UPa_UPA00105	xenobiotic degradation		Degradation of biphenyl, an aromatic hydrocarbon, comprised of two, six-sided aromatic rings connected at one carbon on each ring. It is used as a fungistat in transportation containers of oranges and other citrus fruits, as an intermediate for the production of emulsifiers, optical brighteners, plastics, crop protection products and other organic compounds. It is also used as a heat transfer medium, as a dyestuff carrier for textiles and copying paper, as a solvent in pharmaceutical production, and it was the parent compound of polychlorinated biphenyls (PCBs) (Weaver et al., 1979). Biphenyl is considered to be one of the most thermally stable organic compounds (HSDB, 1991). Animal studies have indicated that biphenyl exposure results in morphological and histopathological changes in the urinary system and it is considered to be a possible mutagen based on in-vitro studies (Boehncke et al., 2005). Various aerobic bacteria are capable of degrading biphenyl via the bhp encoded pathway (Catelani et al., 1971 and Haddock et al., 1993), which is also capable of degrading low chlorinated PCBs. [Rehmann L, Daugulis AJ., Chemosphere. 2006 May;63(6):972-9.].
http://purl.obolibrary.org/obo/UPa_UPA00156	benzoate degradation via hydroxylation	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Degradation of benzoic acid via hydroxylation pathway. This aerobic pathway includes hydroxylation of the aromatic ring by monooxygenases or dioxygenases, whereby catechol (1,2-dihydroxybenzene) or protocatechuate (3,4-dihydroxybenzoate) is produced. These central aromatic intermediates are the substrates for ring-cleaving dioxygenases.
http://purl.obolibrary.org/obo/UPa_UPA00157	beta-ketoadipate pathway	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		The classical beta-ketoadipate pathway: ortho cleavage of catechol (1,2-dihydroxybenzene) or protocatechuate (3,4-dihydroxybenzoate) ring leads to beta-ketoadipate (3-oxoadipate), which is subsequently converted to succinyl-coenzyme A (CoA) and acetyl-CoA.
http://purl.obolibrary.org/obo/UPa_UPA00158	urea cycle	http://purl.obolibrary.org/obo/UPa_UPA00045	nitrogen metabolism		The urea cycle, also known as the ornithine cycle, is a cycle of biochemical reactions occurring in many animal organisms that produces urea from ammonia (NH4+). This cycle was the first metabolic cycle discovered (Krebs and Hensenleit, 1932) [Wikipedia]. Arginine from the diet or from protein breakdown is cleaved by the cytosolic enzyme arginase, generating urea and ornithine. In subsequent reactions of the urea cycle a new urea residue is built on the ornithine, regenerating arginine and perpetuating the cycle.
http://purl.obolibrary.org/obo/UPa_UPA00159	CTP biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00576	CTP biosynthesis		De novo biosynthesis of CTP starting from UMP.
http://purl.obolibrary.org/obo/UPa_UPA00171	pentalenene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00974	pentalenolactone biosynthesis		Biosynthesis of pentalenene, a tricyclic sesquiterpene that is the hydrocarbon precursor of the pentalenolactone family of antibiotics. Pentalenene is produced by the cyclization of farnesyl diphosphate.
http://purl.obolibrary.org/obo/UPa_UPA00177	aristolochene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of aristolochene, a bicyclic eremophilane-type sesquiterpene. Aristolochene (+)-enantiomer is a precursor of mycotoxin PR-toxin in P.roqueforti. It is the likely parent hydrocarbon of several eremophilene toxins and bioregulators produced by a variery of filamentous fungi. The antipodal (-)-enantiomer has been isolated from numerous higher plants.
http://purl.obolibrary.org/obo/UPa_UPA00185	L-arginine degradation via AST pathway	http://purl.obolibrary.org/obo/UPa_UPA00073	L-arginine degradation		Degradation of L-arginine via arginine succinyl transferase pathway. One function of this pathway is to provide nitrogen during nitrogen restriction. The ammonia produced is assimilated into glutamate and glutamine, which in turn provides nitrogen for the synthesis of virtually all nitrogen-containing compounds.
http://purl.obolibrary.org/obo/UPa_UPA00186	agmatine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis		The decarboxylation of L-arginine by arginine decarboxylase produces agmatine. Agmatine is a metabolic intermediate in the biosynthesis of putrescine and higher polyamines (spermidine and spermine). Recent studies indicate that agmatine can have several important biochemical effects in humans, ranging from effects on the central nervous system to cell proliferation in cancer and viral replication.
http://purl.obolibrary.org/obo/UPa_UPA00188	putrescine degradation	http://purl.obolibrary.org/obo/UPa_UPA00457	putrescine metabolism		Degradation of the putrescine polyamine. There are two routes of putrescine degradation to succinate semialdehyde via gamma-aminobutyric acid (GABA).
http://purl.obolibrary.org/obo/UPa_UPA00189	GMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00584	purine biosynthesis		Biosynthesis of GMP (guanosine monophosphate) from IMP (inosine monophosphate).
http://purl.obolibrary.org/obo/UPa_UPA00190	B6 vitamer interconversion	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Interconversion of B6 vitamers (PL, PM, PN, PLP, PMP, PNP).
http://purl.obolibrary.org/obo/UPa_UPA00192	B6 vitamer degradation	http://purl.obolibrary.org/obo/UPa_UPA00483	cofactor degradation		Degradation of B6 vitamers (PL, PM, PN).
http://purl.obolibrary.org/obo/UPa_UPA00208	4-hydroxyphenylacetate degradation	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Degradation of 4-hydroxyphenylacetic acid.
http://purl.obolibrary.org/obo/UPa_UPA00223	tricarboxylic acid cycle	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		The tricarboxylic acid cycle (citric acid cycle, TCA cycle, Krebs cycle, or rarely, the Szent-Gyorgyi-Krebs cycle) is a series of enzyme-catalysed chemical reactions of central importance in all living cells that use oxygen as part of cellular respiration.
http://purl.obolibrary.org/obo/UPa_UPA00241	coenzyme A biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of coenzyme A (CoA), notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle. Coenzyme A is synthesized in a five-step process from pantothenate.
http://purl.obolibrary.org/obo/UPa_UPA00244	pyridoxine 5'-phosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of pyridoxine 5'-phosphate, one of the de novo biosynthesis pathway. In E. coli, this pathway requires PLP as cofactor in its own synthesis.
http://purl.obolibrary.org/obo/UPa_UPA00248	spermidine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00457	putrescine metabolism		Biosynthesis of spermidine by the addition of a propylamine moiety to putrescine.
http://purl.obolibrary.org/obo/UPa_UPA00249	spermine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00826	spermine metabolism		Biosynthesis of spermine by the addition of a propylamine moiety to spermidine.
http://purl.obolibrary.org/obo/UPa_UPA00250	spermidine degradation	http://purl.obolibrary.org/obo/UPa_UPA00826	spermine metabolism		Degradation of permidine polyamine.
http://purl.obolibrary.org/obo/UPa_UPA00251	protoporphyrin-IX biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of protoporphyrin-IX, a porphyrin derivative precursor of heme and chlorphyll compounds.
http://purl.obolibrary.org/obo/UPa_UPA00252	protoheme biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of proteoheme (heme B) from protoporphyrin IX.
http://purl.obolibrary.org/obo/UPa_UPA00253	NAD(+) biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of NAD+ (nicotinamide adenine dinucleotide), a coenzyme found in all living cells. NAD+ is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups: with one nucleotide containing an adenosine ring, and the other containing nicotinamide.
http://purl.obolibrary.org/obo/UPa_UPA00254	L-arginine degradation via ADI pathway	http://purl.obolibrary.org/obo/UPa_UPA00073	L-arginine degradation		Degradation of L-arginine via ADI (arginine deiminase) pathway. In this pathway, L-arginine is converted into ornithine and carbamoyl-phosphate. Carbamoyl-phosphate is further converted into ammonia and CO2 with the concomitant production of ATP. This last part is described as an independant pathway.
http://purl.obolibrary.org/obo/UPa_UPA00257	(R)-mevalonate degradation	http://purl.obolibrary.org/obo/UPa_UPA00498	metabolic intermediate degradation		Degradation of mevalonic acid, a key metabolic intermediate.
http://purl.obolibrary.org/obo/UPa_UPA00258	urea degradation	http://purl.obolibrary.org/obo/UPa_UPA00045	nitrogen metabolism		Degradation of urea.
http://purl.obolibrary.org/obo/UPa_UPA00259	geranyl diphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00416	isoprenoid biosynthesis		Biosynthesis of geranyl-PP (geranyl diphosphate).
http://purl.obolibrary.org/obo/UPa_UPA00260	farnesyl diphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00416	isoprenoid biosynthesis		Biosynthesis of farnesyl-PP (farnesyl diphosphate).
http://purl.obolibrary.org/obo/UPa_UPA00261	L-proline degradation into L-glutamate	http://purl.obolibrary.org/obo/UPa_UPA00532	L-proline degradation		Degradation of L-proline into L-glutamic acid throught two-step oxidation of proline. Enteric bacteria possess a multifunctional flavoprotein, called proline utilization A (PutA), that acts as both a membrane-associated proline catabolic enzyme and a transcriptional repressor of proline utilization (put) genes.
http://purl.obolibrary.org/obo/UPa_UPA00262	siroheme biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of siroheme, the cofactor for sulfite and nitrite reductases. Siroheme is formed by methylation, oxidation, and iron insertion into the tetrapyrrole uroporphyrinogen III (Uro-III).
http://purl.obolibrary.org/obo/UPa_UPA00263	L-ascorbate degradation	http://purl.obolibrary.org/obo/UPa_UPA00483	cofactor degradation		Degradation of L-ascorbic acid (vitamin C). The three gene ulaABC (formerly known as sgaTBA) encode the three components of the L-ascorbate phosphotransferase transport system (UlaABC). They are involved in the uptake and phosphorylation of L-ascorbate [PMID:12644495. Intracellular L-ascorbate-6-P is then transformed by L-ascorbate-6-P lactonase into 3-keto-L-gulonate-6-P. It has been proposed that this compound is decarboxylated by UlaD to L-xylulose-5-P, which is then converted to D-xylulose-5-P by the sequential actions of UlaE (encoding 3-epimerase activity) and UlaF (encoding 4-epimerase activity).
http://purl.obolibrary.org/obo/UPa_UPA00265	1,2-dichloroethane degradation	http://purl.obolibrary.org/obo/UPa_UPA00007	haloalkane degradation		Degradation of 1,2-dichloroethane (1,2-DCA). The greatest use of 1,2-dichloroethane is in making chemicals involved in plastics, rubber and synthetic textile fibers. Other uses include: as a solvent for resins and fats, photography, photocopying, cosmetics, drugs; and as a fumigant for grains and orchards. It is possibly carcinogenic to humans (Group 2B).
http://purl.obolibrary.org/obo/UPa_UPA00269	heme A biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of heme A, a prosthetic group in many respiratory oxidases. It is synthesised from heme B (protoheme IX) with heme O as an intermediate. In Bacillus subtilis two genes required for heme A synthesis, ctaA and ctaB, have been identified. CtaB is the heme O synthase and CtaA is involved in the conversion of heme O to heme A. The model described by Brown et al. [PMID:10675592] is that Heme O Synthase (HOS) and Heme A Synthase (HAS) form a complex and that heme O is transferred directly from HOS to HAS. The biochemical reactions are not yet clearly defined.
http://purl.obolibrary.org/obo/UPa_UPA00272	benzene degradation	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Oxidation of benzene to catechol via cis-benzene glycol (cis-1,2 -dihydroxy-cyclohexa-3,5-diene, cis-1,2-dihydrobenzene-1,2-diol). The conversion of benzene to catechol is performed in two steps catalyzed by benzene dioxygenase and cis-benzene glycol dehydrogenase. Benzene dioxygenase, catalyzing the oxidation of benzene to cis-benzene glycol, is a multicomponent enzyme system.
http://purl.obolibrary.org/obo/UPa_UPA00273	toluene degradation	http://purl.obolibrary.org/obo/UPa_UPA00433	aromatic compound metabolism		Oxidation of toluene to 3-methylcatechol via toluene-cis dihydrodiol.
http://purl.obolibrary.org/obo/UPa_UPA00274	creatinine degradation	http://purl.obolibrary.org/obo/UPa_UPA00456	amine and polyamine degradation		Degradation of creatinine (1-methylglycocyamidine). Creatinine is a readily available nitrogen source found in the faeces of different animals, including earthworms and birds. A number of bacteria utilizing this compound as carbon and/or nitrogen source has already been described for example, Alcaligenes, Arthrobacter, Corynebacterium, Flavobacterium, and Pseudomonas species.
http://purl.obolibrary.org/obo/UPa_UPA00275	riboflavin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of riboflavin (vitamin B2), the universal precursor of flavocoenzymes. It is biosynthesized by plants and many microorganisms but must be obtained from dietary sources by animals.
http://purl.obolibrary.org/obo/UPa_UPA00276	FMN biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of FMN (riboflavin-5-phosphate) cofactor.
http://purl.obolibrary.org/obo/UPa_UPA00277	FAD biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		Biosynthesis of FAD (flavin adenine dinucleotide).
http://purl.obolibrary.org/obo/UPa_UPA00283	germacradienol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of the sesquiterponoid germacradienol ((1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol).
http://purl.obolibrary.org/obo/UPa_UPA00285	germacrene D biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00449	sesquiterpene biosynthesis		Biosynthesis of the sesquiterponoid germacrene D.
http://purl.obolibrary.org/obo/UPa_UPA00288	glycine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00403	proteinogenic amino-acid biosynthesis		Biosynthesis of glycine amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00290	choline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00503	choline metabolism		Biosynthesis of choline.
http://purl.obolibrary.org/obo/UPa_UPA00291	betaine degradation	http://purl.obolibrary.org/obo/UPa_UPA00503	choline metabolism		Degradation of betaine (trimethylaminoacetate, N,N,N-trimethylglycine).
http://purl.obolibrary.org/obo/UPa_UPA00292	sarcosine degradation	http://purl.obolibrary.org/obo/UPa_UPA00456	amine and polyamine degradation		Degradation of sarcosine.
http://purl.obolibrary.org/obo/UPa_UPA00294	formaldehyde assimilation via RuMP pathway	http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism		Formaldehyde is the key intermediate in C1 metabolism and can be assimilated via the ribulose monophosphate (RuMP) pathway. The ribulose monophosphate (RuMP) pathway, involving 3-hexulose-6-phosphate synthase (HPS) and 6-phospho-3-hexuloisomerase (PHI), is now recognized as a widespread prokaryotic pathway for formaldehyde fixation and detoxification. The RuMP pathways consists of three main parts: i) fixation, ii) cleavage and iii) rearrangement. i) Fixation stage: formaldehyde and ribulose-5-phosphate (RuMP) are condensed to form hexulose-6-phosphate (HuMP), which in turn is converted to fructose-6-phosphate (FMP) by hexulosephosphate isomerase (HPI). By the assimilation of three formaldehyde molecules, three molecules of FMP are created.
http://purl.obolibrary.org/obo/UPa_UPA00300	trehalose degradation	http://purl.obolibrary.org/obo/UPa_UPA00443	trehalose metabolism		Degradation of trehalose, also known as mycose, a disaccharide found extensively but not abundantly in nature. Trehalose is metabolized by a number of bacteria, including Streptococcus mutans, the common oral bacteria responsible for oral plaque. The enzyme trehalase, a glycoside hydrolase, present but not abundant in most people, breaks trehalose into two glucose molecules, which can then be readily absorbed in the gut.
http://purl.obolibrary.org/obo/UPa_UPA00306	(S)-reticuline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00510	isoquinoline alkaloid biosynthesis		Biosynthesis of (S)-reticuline, an important intermediate in synthesizing isoquinoline alkaloids. Reticuline is an important intermediate in the production of analgesic morphinan alkaloids (e.g. morphine), antimicrobial berberine alkaloids (e.g. berberine), and antimicrobial benzophenanthridine alkaloids (e.g. sanguinarine).
http://purl.obolibrary.org/obo/UPa_UPA00307	palmatine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00510	isoquinoline alkaloid biosynthesis		Biosynthesis of palmatine, an isoquinoline alkaloid.
http://purl.obolibrary.org/obo/UPa_UPA00308	berbamunine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00510	isoquinoline alkaloid biosynthesis		Biosynthesis of berbamunine, an isoquinoline alkaloid.
http://purl.obolibrary.org/obo/UPa_UPA00311	3alpha(S)-strictosidine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00512	terpenoid indole alkaloid biosynthesis		Biosynthesis of 3-alpha-(S)-strictosidine, an important intermediate in synthesizing indole alkaloids. Strictosidine is is a common biosynthetic precursor for more than two thousand terpene indole alkaloids (e.g production of clinically useful antitumor alkaloids vinblastine and vincristine).
http://purl.obolibrary.org/obo/UPa_UPA00314	L-homocysteine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00406	nonprotein amino-acid biosynthesis		Biosynthesis of homocysteine, the precursor of L-methionine, from S-adenosylhomocysteine. This reaction occurs during the activated methyl cycle.
http://purl.obolibrary.org/obo/UPa_UPA00315	S-adenosyl-L-methionine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00406	nonprotein amino-acid biosynthesis		Biosynthesis of S-adenosyl-L-methionine (SAM, AdoMet). Conversion of L-methionine and ATP into S-adenosyl-L-methionine (AdoMet, SAM), which is required for methyltransferase reactions in the cell as well as for polyamine biosynthesis. This reaction occurs during the activated methyl cycle.
http://purl.obolibrary.org/obo/UPa_UPA00319	(S)-scoulerine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00510	isoquinoline alkaloid biosynthesis		Biosynthesis of scoulerine, an isoquinoline alkaloid. Scoulerine is is a precursor of protopine, protoberberine and benzophenanthridine alkaloid biosynthesis in plants. Some studies shown that scoulerine is an antagonist at the alpha-2-adrenoceptor, alpha-1D-adrenoceptor and 5-HT receptor [PMID:7902181] [PMID:7952879]. It has also been found to be a GABA-A receptor agonist [PMID:14577695] [PMID:12709895].
http://purl.obolibrary.org/obo/UPa_UPA00331	S-adenosylmethioninamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00289	amine and polyamine biosynthesis		Biosynthesis of S-adenosylmethioninamine, a precursor of spermine and spermidine polyamines, from S-adenosyl-L-methionine (AdoMet, SAM).
http://purl.obolibrary.org/obo/UPa_UPA00332	L-tryptophan degradation via pyruvate pathway	http://purl.obolibrary.org/obo/UPa_UPA00526	L-tryptophan degradation		Degradation of amino-acid L-tryptophan into pyruvate and indole. Among the multiple products of tryptophan catabolism, indole is suspected to be responsible for the cell-cycle arrest and to add a role in stationary-phase signalling [PMID:17163965].
http://purl.obolibrary.org/obo/UPa_UPA00333	L-tryptophan degradation via kynurenine pathway	http://purl.obolibrary.org/obo/UPa_UPA00526	L-tryptophan degradation		Degradation of amino-acid L-tryptophan into L-kynurenine.
http://purl.obolibrary.org/obo/UPa_UPA00334	L-kynurenine degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of L-kynurenine, a metabolite of L-tryptophan amino-acid.
http://purl.obolibrary.org/obo/UPa_UPA00336	taurine degradation via aerobic pathway	http://purl.obolibrary.org/obo/UPa_UPA00522	organosulfur degradation		Degradation of taurine (2-aminoethanesulfonic acid), an organic acid that is abundant in the tissues of many animals (metazoa). Taurine is also found in plants, fungi, and some bacterial species, but at lower levels. Taurine is a derivative of the sulphur-containing (sulfhydryl) amino-acid, cysteine.
http://purl.obolibrary.org/obo/UPa_UPA00340	acetyl-CoA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of acetyl-CoA, an important molecule in metabolism, used in many biochemical reactions.
http://purl.obolibrary.org/obo/UPa_UPA00355	coenzyme M biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00399	cofactor biosynthesis		De novo biosynthesis of coenzyme M (2-mercaptoethanesulfonic acid, HS-CoM). Warning, this pathway is not fully defined, the last part of the pathway is still missing.
http://purl.obolibrary.org/obo/UPa_UPA00356	ADP-L-glycero-beta-D-manno-heptose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of ADP-L-glycero-beta-D-manno-heptose (ADP-L-beta-D-heptose), a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.
http://purl.obolibrary.org/obo/UPa_UPA00357	3-deoxy-D-manno-octulosonate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		Biosynthesis of 3-deoxy-D-manno-octulosonate (KDO, keto-deoxyoctulonate). In general, KDO residues are normally found in the lipopolysaccharide inner core of gram-negative bacteria, but in K. pneumoniae, this KDO residue provides the ligation site for O polysaccharide. The conserved Klebsiella outer core contains the unusual trisaccharide 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo)-(2,6)-GlcN-(1,4)-GalUA. lipopolysaccharide (LPS).
http://purl.obolibrary.org/obo/UPa_UPA00358	CMP-3-deoxy-D-manno-octulosonate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of CMP-3-deoxy-D-manno-octulosonate (CMP-KDO, CMP-keto-deoxyoctulonate), a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS).
http://purl.obolibrary.org/obo/UPa_UPA00359	lipid IV(A) biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of lipid IV(A), the endotoxically inactive LPS lipid A precursor. Lipid A is one of the three components of lipopolysaccharide (LPS). It contains unusual fatty acids (e.g. hydroxy-myristic acid) and is inserted into the outer membrane while the rest of the LPS projects from the surface. Lipid A, the potent macrophage-activating component primarily responsible for LPS endotoxin activity, is a phosphorylated glucosamine disaccharide carrying long-chain saturated fatty acid (FA) substituents that anchor LPS in the outer membrane. Lipid A is similar for all Gram-negative Enterobacteriaceae, and synthetic lipid A produces effects identical to that isolated from Escherichia coli in both in vitro and in vivo endotoxin tests.
http://purl.obolibrary.org/obo/UPa_UPA00360	KDO(2)-lipid A biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00506	glycolipid biosynthesis		Biosynthesis of KDO(2)-lipid A, a lipopolysaccharide (LPS) component.
http://purl.obolibrary.org/obo/UPa_UPA00365	vindoline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00512	terpenoid indole alkaloid biosynthesis		Biosynthesis of vindoline, an indole alkaloid, precursor of vinblastine and vincristine.
http://purl.obolibrary.org/obo/UPa_UPA00371	sucrose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00484	glycan biosynthesis		Biosynthesis of sucrose (saccharose, 1-alpha-D-glucopyranosyl-2-beta-D-fructofuranoside), a disaccharide composed of glucose and fructose. In most plants, sucrose is the main product of photosynthesis that is exported from the leaves to fuel growth and synthesis of storage reserves, such as starch and oil, and sucrose itself is often accumulated by plant cells to protect against the effects of dehydration under drought, salinity, or cold stress. Apart from plants, some species of cyanobacteria also synthesize sucrose, often in response to osmotic stress.
http://purl.obolibrary.org/obo/UPa_UPA00372	3,4',5-trihydroxystilbene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00422	stilbenoid biosynthesis		Biosynthesis of 3,4',5-trihydroxystilbene (resveratrol), a phytoalexin produced by several plants.
http://purl.obolibrary.org/obo/UPa_UPA00379	L-histidine degradation into L-glutamate	http://purl.obolibrary.org/obo/UPa_UPA00492	L-histidine degradation		Nonoxidative degradation of L-histidine into L-glutamate.
http://purl.obolibrary.org/obo/UPa_UPA00384	ethylene biosynthesis via S-adenosyl-L-methionine	http://purl.obolibrary.org/obo/UPa_UPA00438	plant hormone biosynthesis		Biosynthesis of ethylene, an unsaturated hydrocarbon that contains one double bond (the simplest alkene). It acts as hormon in plant where it is essential for proper development, growth and survival. It is responsible for signaling changes during germination, flower and fruit development, the onset of plant defense responses, and cross-talk with other plant hormones.
http://purl.obolibrary.org/obo/UPa_UPA00389	geranylgeranyl diphosphate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00416	isoprenoid biosynthesis		Biosynthesis of geranylgeranyl-PP (geranylgeranyl diphosphate), a precursor of terpenes and terpenoids.
http://purl.obolibrary.org/obo/UPa_UPA00394	urate degradation	http://purl.obolibrary.org/obo/UPa_UPA00595	purine base degradation		Degradation of uric acid, a key compound in the degradation of purines. The ureide pathway, which mediates the oxidative degradation of uric acid to (S)-allantoin, represents the late stage of purine catabolism in most organisms. The metabolism of uric acid has a pivotal role in transforming the nitrogen that is fixed in leguminous plants and also plays a crucial role in some bacteria under nitrogen-limited conditions.
http://purl.obolibrary.org/obo/UPa_UPA00395	(S)-allantoin degradation	http://purl.obolibrary.org/obo/UPa_UPA00407	ureide metabolism		Anaerobic utilization of (S)-allantoin, a diureide of glyoxylic acid, as nitrogen source.
http://purl.obolibrary.org/obo/UPa_UPA00527	L-alanine degradation via dehydrogenase pathway	http://purl.obolibrary.org/obo/UPa_UPA00491	alanine degradation		Hydrolysis of L-alanine to ammonia and pyruvate.
http://purl.obolibrary.org/obo/UPa_UPA00528	L-alanine degradation via transaminase pathway	http://purl.obolibrary.org/obo/UPa_UPA00491	alanine degradation		Breakdown of alanine via an aminotransferase reaction (transfer of an amino group from glutamate to pyruvate to form 2-oxoglutarate and alanine).
http://purl.obolibrary.org/obo/UPa_UPA00529	betaine biosynthesis via choline pathway	http://purl.obolibrary.org/obo/UPa_UPA00503	choline metabolism		Biosynthesis of betaine (glycine betaine, N,N,N-trimethylglycine) by a two- step oxidation of choline. An alternative pathway converts glycine to betaine through two N-methyltransferases.
http://purl.obolibrary.org/obo/UPa_UPA00530	betaine biosynthesis via glycine pathway	http://purl.obolibrary.org/obo/UPa_UPA00264	betaine biosynthesis		Biosynthesis of betaine (glycine betaine, N,N,N-trimethylglycine) by a three-step series of methylation reactions from glycine.
http://purl.obolibrary.org/obo/UPa_UPA00533	L-glutamate degradation via hydroxyglutarate pathway	http://purl.obolibrary.org/obo/UPa_UPA00553	fermentation		The hydroxyglutarate pathway is one of the major pathways by which L-glutamate amino-acid is fermented. This pathway is found in organisms living in anoxic niches within humans and animals, including members of the genus Acidaminococcus, Clostridium, Fusobacterium and Peptostreptococcus.
http://purl.obolibrary.org/obo/UPa_UPA00534	putrescine biosynthesis via agmatine pathway	http://purl.obolibrary.org/obo/UPa_UPA00187	putrescine biosynthesis		Agmatine, which results from the decarboxylation of L-arginine by arginine decarboxylase, is a metabolic intermediate in the biosynthesis of putrescine and higher polyamines (spermidine and spermine). Recent studies indicate that agmatine can have several important biochemical effects in humans, ranging from effects on the central nervous system to cell proliferation in cancer and viral replication.
http://purl.obolibrary.org/obo/UPa_UPA00535	putrescine biosynthesis via L-ornithine pathway	http://purl.obolibrary.org/obo/UPa_UPA00187	putrescine biosynthesis		The pathway for mammalian putrescine synthesis was demonstrated to occur via the decarboxylation of ornithine.
http://purl.obolibrary.org/obo/UPa_UPA00537	protein lipoylation via exogenous pathway	http://purl.obolibrary.org/obo/UPa_UPA00536	protein lipoylation		Protein lipoylation via exogenous pathway.
http://purl.obolibrary.org/obo/UPa_UPA00538	protein lipoylation via endogenous pathway	http://purl.obolibrary.org/obo/UPa_UPA00536	protein lipoylation		Protein lipoylation via endogenous pathway.
http://purl.obolibrary.org/obo/UPa_UPA00540	oxalate degradation	http://purl.obolibrary.org/obo/UPa_UPA00498	metabolic intermediate degradation		Degradation of oxalate. Because of its toxicity, oxalate accumulation from amino-acid catabolism leads to acute disorders in mammals. Gut microflora are therefore pivotal in maintaining a safe intestinal oxalate balance through oxalate degradation. Oxalate catabolism was first identified in Oxalobacter formigenes, a specialized, strictly anaerobic bacterium. Oxalate degradation was found to be performed successively by two enzymes, a formyl-CoA transferase (frc) and an oxalate decarboxylase (oxc). These two genes are present in several bacterial genomes including that of Escherichia coli.
http://purl.obolibrary.org/obo/UPa_UPA00541	L-rhamnose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of L-rhamnose (hexose 6-deoxy-L-mannose).
http://purl.obolibrary.org/obo/UPa_UPA00542	lactose degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of lactose, a disaccharide that consists of beta-D-galactose and beta-D-glucose molecules bonded through a beta-1-4 glycosidic linkage.
http://purl.obolibrary.org/obo/UPa_UPA00543	GDP-D-glycero-alpha-D-manno-heptose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of GDP-D-glycero-alpha-D-manno-heptose (GDP-D-beta-D-heptose), a nucleotide-sugar present in S-layer glycoproteins or capsular polysaccharide or flagella.
http://purl.obolibrary.org/obo/UPa_UPA00551	cyclic 2,3-diphosphoglycerate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00550	thermoadapter biosynthesis		Biosynthesis of cyclic 2, 3-diphosphoglycerate (cDPG), a trianionic compound acting as thermoadapter in thermophile organisms.
http://purl.obolibrary.org/obo/UPa_UPA00554	pyruvate fermentation to lactate	http://purl.obolibrary.org/obo/UPa_UPA00699	organic acid degradation		Conversion of pyruvate (the final product of glycolysis) to lactate in the absence of oxygen.
http://purl.obolibrary.org/obo/UPa_UPA00557	CDP-diacylglycerol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00751	phospholipid biosynthesis		Biosynthesis of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a molecule composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.
http://purl.obolibrary.org/obo/UPa_UPA00558	phosphatidylethanolamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00751	phospholipid biosynthesis		Biosynthesis of phosphatidylethanolamine compounds, any of a class of phospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
http://purl.obolibrary.org/obo/UPa_UPA00561	L-glutamate degradation via mesaconate pathway	http://purl.obolibrary.org/obo/UPa_UPA00553	fermentation		The mesaconate pathway is one of the major pathways by which L-glutamate amino-acid is fermented.
http://purl.obolibrary.org/obo/UPa_UPA00562	formaldehyde degradation	http://purl.obolibrary.org/obo/UPa_UPA00445	one-carbon metabolism		Degradation of formaldehyde, a toxic compound for all organisms from bacteria to humans due to its reactivity with biological macromolecules (nonspecific reactivity with proteins and nucleic acids). Organisms that grow aerobically on single-carbon compounds such as methanol and methane face a special challenge in this regard because formaldehyde is a central metabolic intermediate during methylotrophic growth.
http://purl.obolibrary.org/obo/UPa_UPA00563	L-fucose degradation	http://purl.obolibrary.org/obo/UPa_UPA00956	L-fucose metabolism		Degradation of the methylpentose L-fucose (6-deoxygalactose).
http://purl.obolibrary.org/obo/UPa_UPA00564	D-glucarate degradation	http://purl.obolibrary.org/obo/UPa_UPA00794	aldaric acid degradation		Degradation of D-glucaric acid, an aldaric acid.
http://purl.obolibrary.org/obo/UPa_UPA00565	galactarate degradation	http://purl.obolibrary.org/obo/UPa_UPA00794	aldaric acid degradation		Degradation of galactarate, an aldaric acid.
http://purl.obolibrary.org/obo/UPa_UPA00574	UMP biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00573	pyrimidine salvage		Biosynthesis of UMP via salvage of pyrimidine derivatives (cytidine, uridine, cytosine).
http://purl.obolibrary.org/obo/UPa_UPA00578	dTMP biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00577	dTMP biosynthesis		Biosynthesis of dTMP via pyrimidine salvage pathway.
http://purl.obolibrary.org/obo/UPa_UPA00579	CTP biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00576	CTP biosynthesis		Biosynthesis of CTP starting from cytidine (salvage pathway).
http://purl.obolibrary.org/obo/UPa_UPA00582	uracil degradation via oxidative pathway	http://purl.obolibrary.org/obo/UPa_UPA00581	uracil degradation		Oxidative degradation of uracil nucleobase.
http://purl.obolibrary.org/obo/UPa_UPA00588	AMP biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00592	AMP biosynthesis		Biosynthesis of AMP through purine salvage.
http://purl.obolibrary.org/obo/UPa_UPA00591	IMP biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00648	IMP biosynthesis		Biosynthesis of inosine 5'-phosphate (IMP) through purine salvage.
http://purl.obolibrary.org/obo/UPa_UPA00601	XMP biosynthesis via de novo pathway	http://purl.obolibrary.org/obo/UPa_UPA00600	XMP biosynthesis		Biosynthesis of xanthosine 5'-phosphate (XMP purine nucleotide) via de novo pathway.
http://purl.obolibrary.org/obo/UPa_UPA00602	XMP biosynthesis via salvage pathway	http://purl.obolibrary.org/obo/UPa_UPA00600	XMP biosynthesis		Biosynthesis of xanthosine 5'-phosphate (XMP purine nucleotide) via salvage pathway.
http://purl.obolibrary.org/obo/UPa_UPA00603	guanine degradation	http://purl.obolibrary.org/obo/UPa_UPA00595	purine base degradation		Degradation of guanine purine nucleobase.
http://purl.obolibrary.org/obo/UPa_UPA00604	hypoxanthine degradation	http://purl.obolibrary.org/obo/UPa_UPA00595	purine base degradation		Degradation of hypoxanthine purine base into uric acid.
http://purl.obolibrary.org/obo/UPa_UPA00609	CDP-diacylglycerol degradation	http://purl.obolibrary.org/obo/UPa_UPA00752	phospholipid degradation		Degradation of CDP-diacylglycerol compounds.
http://purl.obolibrary.org/obo/UPa_UPA00610	dUMP biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00571	pyrimidine biosynthesis		Biosynthesis of dUMP (deoxyuridine 5'-phosphate), a pyrimidine deoxyribonucleotide.
http://purl.obolibrary.org/obo/UPa_UPA00617	glycerol fermentation	http://purl.obolibrary.org/obo/UPa_UPA00616	glycerol degradation		In the absence of an external oxidant, glycerol is consumed by a dismutation process involving two sub-pathways. Through one sub-pathway (oxidative route), glycerol is dehydrogenated by an NAD+-linked glycerol dehydrogenase (DhaD) to dihydroxyacetone. This product is then phosphorylated by dihydroxyacetone kinase (DhaK) and funnelled to the central metabolism. Through the other sub-pathway (reductive route), glycerol is dehydrated by coenzyme B12-dependent glycerol dehydratase (DhaB, DhaC, DhaE) to form 3-hydroxypropionaldehyde, which is reduced to the major fermentation product 1,3-propanediol by the NADH-linked 1,3-propanediol dehydrogenase (DhaT), thereby regenerating NAD+ [PMID: 9311132].
http://purl.obolibrary.org/obo/UPa_UPA00618	glycerol degradation via glycerol kinase pathway	http://purl.obolibrary.org/obo/UPa_UPA00616	glycerol degradation		In bacteria, glycerol uptake is mediated by the glycerol diffusion facilitator, an integral membrane protein catalyzing the rapid equilibration of concentration gradients of glycerol across the cytoplasmic membrane. Intracellular glycerol is converted to glycerol-3-phosphate that is further metabolized to dihydroxyacetone phosphate (DHAP) by either of two membrane-bound enzymes, depending on the growth conditions.
http://purl.obolibrary.org/obo/UPa_UPA00619	methylglyoxal degradation	http://purl.obolibrary.org/obo/UPa_UPA00465	secondary metabolite metabolism		Methylglyoxal (MG) is a cytotoxic compound formed primarily as a by-product of carbohydrate and lipid metabolism. It is catabolised by glyoxalases I and II, the zinc-binding enzymes of the glyoxalase pathway. Glyoxalase system is present in the cytosol of cells and cellular organelles, particularly mitochondria.
http://purl.obolibrary.org/obo/UPa_UPA00626	(R,R)-butane-2,3-diol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00625	(R,R)-butane-2,3-diol metabolism		In some bacteria, pyruvate can be channeled via alpha-acetolactate into neutral compound 2,3-butanediol. The production of (R,R)-2,3-butanediol is enhanced when oxygen is limited and the pH is lowered.
http://purl.obolibrary.org/obo/UPa_UPA00629	N-acetylneuraminate degradation	http://purl.obolibrary.org/obo/UPa_UPA00628	N-acetylneuraminate metabolism		Degradation of N-acetylneuraminate, an amino sugar component of the cell surface structures. N-acetylneuraminate is possibly used as carbon and nitrogen sources.
http://purl.obolibrary.org/obo/UPa_UPA00634	L-glutamate biosynthesis via GLT pathway	http://purl.obolibrary.org/obo/UPa_UPA00633	L-glutamate biosynthesis		Biosynthesis of L-glutamate amino-acid via glutamate synthase (GLT).
http://purl.obolibrary.org/obo/UPa_UPA00640	methanogenesis from CO(2)	http://purl.obolibrary.org/obo/UPa_UPA00639	methanogenesis		Biosynthesis of methane from CO(2) (carbon dioxide).
http://purl.obolibrary.org/obo/UPa_UPA00646	methyl-coenzyme M reduction	http://purl.obolibrary.org/obo/UPa_UPA00639	methanogenesis		The conversion of methyl-CoM to methane is the final step in the methanogenesis process. This process involves the reduction of the coenzyme M-bound methyl group to methane. This step is catalyzed by methyl-coenzyme M reductase (MCR), a key enzyme that is found in all methanogens.
http://purl.obolibrary.org/obo/UPa_UPA00647	coenzyme M-coenzyme B heterodisulfide reduction	http://purl.obolibrary.org/obo/UPa_UPA00639	methanogenesis		All processes in methanogenesis lead to the formation of a mixed disulfide bond between coenzyme M and coenzyme B, by a reaction in which coenzyme B reduces methyl-coenzyme M , leading to formation of methane and a coenzyme M-coenzyme B heterodisulfide [PMID:12102556] . There are two different systems that are capable of reducing the coenzyme M-coenzyme B heterodisulfide, using either H2 or a reduced coenzyme F420 as electron donors [PMID:15168610].
http://purl.obolibrary.org/obo/UPa_UPA00652	nitrate reduction (denitrification)	http://purl.obolibrary.org/obo/UPa_UPA00654	nitrate reduction		Denitrification is the process of reducing nitrate and nitrite, highly oxidised forms of nitrogen available for consumption by many groups of organisms, into gaseous nitrogen, which is far less accessible to life forms but makes up the bulk of atmosphere. Denitrification can be thought of as the opposite of nitrogen fixation. In general, denitrification occurs when oxygen is depleted, and bacteria turn to nitrate in order to respire organic matter. Denitrification proceeds through some combination of the following steps: nitrate -> nitrite -> nitric oxide -> nitrous oxide -> dinitrogen gas.
http://purl.obolibrary.org/obo/UPa_UPA00655	malonyl-CoA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of malonyl-CoA.
http://purl.obolibrary.org/obo/UPa_UPA00702	D-galactose 6-phosphate degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of D-galactose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UPA00703	glyoxylate cycle	http://purl.obolibrary.org/obo/UPa_UPA00411	carbohydrate metabolism		Glyoxylate cycle is a metabolic pathway occurring in plants, certain vertebrates, and several microorganisms, such as E. coli and yeast. The glyoxylate cycle allows these organisms to use fats for the synthesis of carbohydrates, a task which most vertebrates, including humans, cannot perform. The glyoxylate cycle, avoids the steps in the citric acid cycle (TCA cycle) where carbon is lost in the form of CO2. The two initial stages of this cycle are identical to those of the TCA cycle: acetate -> citrate -> isocitrate. The next step, however, is different: instead of decarboxylation, isocitrate undergoes cleavage into succinate and glyoxylate (the latter gives the cycle its name). Succinate can be channeled directly into the citric acid cycle and eventually form oxaloacetate. Glyoxylate condenses with acetyl-CoA, yielding malate. Both malate and oxaloacetate can be converted into phosphoenolpyruvate and gluconeogenesis can be initiated. The net result of the glyoxylate cycle is therefore the production of glucose from fatty acids. In plants the glyoxylate cycle occurs in special peroxisomes which are called glyoxysomes. Vertebrates cannot perform the cycle because they lack its two key enzymes: isocitrate lyase and malate synthase.
http://purl.obolibrary.org/obo/UPa_UPA00704	D-tagatose 6-phosphate degradation	http://purl.obolibrary.org/obo/UPa_UPA00413	carbohydrate degradation		Degradation of D-tagatose 6-phosphate.
http://purl.obolibrary.org/obo/UPa_UPA00713	trans-cinnamate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00711	phenylpropanoid biosynthesis		Biosynthesis of cinnamic acid (3-phenyl-2-propenoic acid), a phenylpropanoid compound.
http://purl.obolibrary.org/obo/UPa_UPA00714	3-phenylpropanoate degradation	http://purl.obolibrary.org/obo/UPa_UPA00712	phenylpropanoid degradation		Degradation of 3-phenylpropionic acid, a phenylpropanoid compound.
http://purl.obolibrary.org/obo/UPa_UPA00726	phthalate degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of phtalate (benzene-1,2-dicarboxylate).
http://purl.obolibrary.org/obo/UPa_UPA00747	dopamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00746	catecholamine biosynthesis		Biosynthesis of dopamine (DA; 4-(2-aminoethyl)benzene-1,2-diol), a catecholamine neurotransmitter and a metabolic precursor of adrenaline (epinephrine), noradrenaline (norepinephrine).
http://purl.obolibrary.org/obo/UPa_UPA00748	(R)-noradrenaline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00746	catecholamine biosynthesis		Biosynthesis of L-noradrenaline (norepinephrine), an hormone produced by the medulla of the adrenal glands.
http://purl.obolibrary.org/obo/UPa_UPA00749	(R)-adrenaline biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00746	catecholamine biosynthesis		Biosynthesis of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
http://purl.obolibrary.org/obo/UPa_UPA00753	phosphatidylcholine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00947	glycerophospholipid biosynthesis		Biosynthesis of phosphatidylcholine, also called lecithin, a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. Phosphatidylcholine is the most-abundant phospholipid found in eukaryotic membranes. Additionally to its structural function in membrane bilayers and lipoproteins, phosphatidylcholine is involved in many signal transduction pathways. Phosphatidylcholine has also been found in an increasing number of bacteria, in particular in species that interact with eukaryotic hosts.
http://purl.obolibrary.org/obo/UPa_UPA00757	dhurrin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00464	secondary metabolite biosynthesis		Biosynthesis of dhurrin, a tyrosine derived cyanogenic glucoside. Dhurrin functions as a plant defense compound. Cyanogenic glucosides are amino-acid-derived natural products. The ability to synthesize these glucosides is common across many plant genera, including several plant species that are important crop plants like sorghum (Sorghum bicolor), cassava (Manihot esculenta), flax (Linum usitatissimum) and almonds (Prunus dulcis).
http://purl.obolibrary.org/obo/UPa_UPA00762	3',5'-cyclic AMP degradation	http://purl.obolibrary.org/obo/UPa_UPA00761	purine nucleotide degradation		Degradation of cAMP into AMP.
http://purl.obolibrary.org/obo/UPa_UPA00763	3',5'-cyclic GMP degradation	http://purl.obolibrary.org/obo/UPa_UPA00761	purine nucleotide degradation		Degradation of cyclic GMP nucleotide into GMP.
http://purl.obolibrary.org/obo/UPa_UPA00764	cyclopentanol degradation	http://purl.obolibrary.org/obo/UPa_UPA00612	alcohol degradation		Degradation of cyclopentanol, a cyclic alcohol.
http://purl.obolibrary.org/obo/UPa_UPA00767	lanosterol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00062	steroid biosynthesis		Biosynthesis of lanosterol, a tetracyclic triterpenoid precursor to the whole family of steroids.
http://purl.obolibrary.org/obo/UPa_UPA00768	ergosterol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00766	sterol biosynthesis		Biosynthesis of ergosterol (ergosta-5,7,22-trien-3beta-ol) from zymosterol. Ergosterol is a sterol precursor to Vitamin D2 compounds.
http://purl.obolibrary.org/obo/UPa_UPA00770	zymosterol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00766	sterol biosynthesis		Biosynthesis of zymosterol (5alpha-cholesta-8,24-dien-3beta-ol), a sterol precursor to cholesterol or ergosterol.
http://purl.obolibrary.org/obo/UPa_UPA00771	D-erythroascorbate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00412	carbohydrate biosynthesis		D-erythroascorbate (EASC), a five-carbon analog of L-ascorbate (ASC) is present in some eukaryotic microorganisms where ASC is rare or absent. In Candida albicans and Saccharomyces cerevisiae, the biosynthetic pathway of EASC from D-arabinose by D-arabinose dehydrogenase and D-arabinono-1,4-lactone oxidase has been established. EASC has biological properties similar to those of ASC. Considering that some eukaryotic microorganisms produce EASC instead of ASC, it is presumed that EASC may take the place of ASC in these microorganisms. EASC has been proved an important antioxidant molecule in S. cerevisiae, like ASC in animals and plants.
http://purl.obolibrary.org/obo/UPa_UPA00780	ethanol degradation	http://purl.obolibrary.org/obo/UPa_UPA00779	ethanol metabolism		Degradation of ethanol.
http://purl.obolibrary.org/obo/UPa_UPA00784	fructoselysine degradation	http://purl.obolibrary.org/obo/UPa_UPA00427	amino-acid degradation		Degradation of fructolysine, a fructose molecule containing a lysine moiety in place of an hydroxyl group. Escherichia coli was found to grow on fructoselysine as an energetic substrate at a rate of about one-third of that observed with glucose.
http://purl.obolibrary.org/obo/UPa_UPA00796	UDP-alpha-D-xylose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of UDP-D-xylose, a nucleotide sugar used to initiate glycosaminoglycan biosynthesis on the core protein of proteoglycans.
http://purl.obolibrary.org/obo/UPa_UPA00797	UDP-L-arabinose biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00304	nucleotide-sugar biosynthesis		Biosynthesis of the nucleotide sugar, UDP-arabinose.
http://purl.obolibrary.org/obo/UPa_UPA00799	phytoene biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00418	carotene biosynthesis		Biosynthesis of phytoene, an acyclic carotene precursor to carotenoids.
http://purl.obolibrary.org/obo/UPa_UPA00806	capsanthin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis		Biosynthesis of capsanthin, a xantophyll carotenoid.
http://purl.obolibrary.org/obo/UPa_UPA00807	capsorubin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00419	xantophyll biosynthesis		Biosynthesis of capsorubin, a xantophyll carotenoid.
http://purl.obolibrary.org/obo/UPa_UPA00808	dibenzofuran degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of dibenzofuran. Dibenzofuran is created as by-products during industrial processes such as incineration, paper bleaching, and chemical synthesis. It has also been used as an insecticide, and is formed from the photolysis of chlorinated biphenyl ethers. Several species of bacteria capable degrading dibenzofuran have been identified, including Pseudomonas, Xanthomonas, Terrabacter, Microbacterium, and Rhodococcus.
http://purl.obolibrary.org/obo/UPa_ULS00002	beta-alanine from L-aspartate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00003	(R)-pantoate from 3-methyl-2-oxobutanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00004	(R)-pantothenate from (R)-pantoate and beta-alanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00005	L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00006	(S)-tetrahydrodipicolinate from L-aspartate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00007	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (succinylase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00008	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (acetylase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00009	DL-2,6-diaminopimelate from LL-2,6-diaminopimelate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00010	DL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00011	L-lysine from DL-2,6-diaminopimelate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00012	L-alpha-aminoadipate from 2-oxoglutarate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00013	L-lysine from L-alpha-aminoadipate (fungal route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00014	L-lysine from L-alpha-aminoadipate (Thermus route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00015	sulfoacetaldehyde from phosphoenolpyruvate and sulfite	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00016	L-tryptophan from chorismate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00017	3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00018	2-oxobutanoate from L-threonine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00019	2-oxobutanoate from pyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00020	L-isoleucine from 2-oxobutanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00021	L-valine from pyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00022	L-threonine from L-aspartate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00023	L-leucine from 3-methyl-2-oxobutanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00025	L-homoserine from L-aspartate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00026	O-acetyl-L-homoserine from L-homoserine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00027	O-succinyl-L-homoserine from L-homoserine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00028	L-homocysteine from S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00029	L-cystathionine from O-succinyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00030	L-homocysteine from L-cystathionine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00031	L-homocysteine from O-acetyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00032	S-adenosyl-L-methionine from L-methionine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00033	L-methionine from L-homocysteine (MetH route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00034	L-methionine from L-homocysteine (MetE route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00035	L-methionine from L-homocysteine (BhmT route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00036	chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00037	isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00038	isopentenyl diphosphate from (R)-mevalonate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00039	(R)-mevalonate from acetyl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00040	1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00041	dimethylallyl diphosphate from isopentenyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00042	dimethylallyl diphosphate from (2E)-4-hydroxy-3-methylbutenyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00043	N(2)-acetyl-L-ornithine from L-glutamate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00044	L-ornithine from N(2)-acetyl-L-ornithine (linear)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00045	L-ornithine and N-acetyl-L-glutamate from L-glutamate and N(2)-acetyl-L-ornithine (cyclic)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00046	L-arginine from L-ornithine and carbamoyl phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00048	L-ectoine from L-aspartate 4-semialdehyde	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00049	D-xylulose 5-phosphate from L-arabinose (bacterial route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00050	N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00051	N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00052	N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (formate route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00054	5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00055	5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (formate route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00056	IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00057	4-amino-2-methyl-5-diphosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00058	4-methyl-5-(2-phosphoethyl)-thiazole from 5-(2-hydroxyethyl)-4-methylthiazole	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00059	4-methyl-5-(2-phosphoethyl)-thiazole from 1-deoxy-D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00060	thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00061	acetyl-CoA from myo-inositol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00062	4-aminobenzoate from chorismate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00063	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00064	7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00067	formate from 10-formyl-5,6,7,8-tetrahydrofolate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00068	carbamoyl phosphate from bicarbonate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00069	D-glucuronate from myo-inositol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00070	5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00071	5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00072	3-dehydroquinate from D-quinate (NAD(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00073	3-dehydroquinate from D-quinate (PQQ route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00074	3,4-dihydroxybenzoate from 3-dehydroquinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00075	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00076	D-glyceraldehyde 3-phosphate from glycerone phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00077	pyruvate from D-glyceraldehyde 3-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00078	GDP-L-fucose from GDP-alpha-D-mannose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00079	2-(alpha-D-mannosyl)-D-glycerate from GDP-alpha-D-mannose (MPG route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00080	L-asparagine from L-aspartate (ammonia route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00081	L-asparagine from L-aspartate (L-Gln route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00082	L-serine from 3-phospho-D-glycerate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00083	L-cysteine from L-serine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00084	L-cysteine from L-homocysteine and L-serine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00085	prephenate from chorismate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00086	sulfite from sulfate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00087	hydrogen sulfide from sulfite (NADPH route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00088	hydrogen sulfide from sulfite (ferredoxin route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00089	glutathione from L-cysteine and L-glutamate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00090	precorrin-2 from uroporphyrinogen III	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00091	cob(II)yrinate a,c-diamide from precorrin-2 (aerobic route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00092	cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00093	adenosylcobalamin from cob(II)yrinate a,c-diamide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00094	penicillin G from L-alpha-aminoadipate and L-cysteine and L-valine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00095	clavulanate from D-glyceraldehyde 3-phosphate and L-arginine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00096	2-hydroxy-2,4-pentadienoate and benzoate from biphenyl	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00097	catechol from benzoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00098	3,4-dihydroxybenzoate from benzoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00099	5-oxo-4,5-dihydro-2-furylacetate from catechol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00100	3-oxoadipate from 5-oxo-4,5-dihydro-2-furylacetate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00101	acetyl-CoA and succinyl-CoA from 3-oxoadipate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00102	3-carboxy-cis,cis-muconate from 3,4-dihydroxybenzoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00103	3-oxoadipate from 3,4-dihydroxybenzoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00104	betaine from glycine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00105	UDP from UMP (UMK/CMK route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00106	UDP from UMP (UMPK route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00107	CTP from UDP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00108	CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00109	L-glutamate and succinate from L-arginine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00110	agmatine from L-arginine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00111	N-carbamoylputrescine from agmatine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00112	putrescine from agmatine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00113	putrescine from L-ornithine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00114	4-aminobutanal from putrescine (amine oxidase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00115	4-aminobutanal from putrescine (transaminase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00117	XMP from IMP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00118	GMP from XMP (L-Gln route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00119	GMP from XMP (ammonia route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00120	pyridoxal 5'-phosphate from pyridoxal	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00121	pyridoxamine 5'-phosphate from pyridoxamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00122	pyridoxine 5'-phosphate from pyridoxine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00123	pyridoxal from pyridoxal 5'-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00124	pyridoxamine from pyridoxamine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00125	pyridoxine from pyridoxine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00126	pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00127	pyridoxal 5'-phosphate from pyridoxine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00128	pyridoxal from pyridoxamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00129	pyridoxal from pyridoxine (dehydrogenase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00130	5-oxo-4,5-dihydro-2-furylacetate from 3-carboxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00131	3-carboxy-cis,cis-muconate from 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00132	pyridoxine 5'-phosphate from D-erythrose 4-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00133	4-aminobutanoate from 4-aminobutanal	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00134	succinate semialdehyde from 4-aminobutanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00135	1,3-diaminopropane and 4-aminobutanal from spermidine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00136	spermidine from putrescine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00137	spermine from spermidine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00138	5-aminolevulinate from L-glutamyl-tRNA(Glu)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00139	protoporphyrinogen-IX from coproporphyrinogen-III (O2 route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00140	protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00141	protoporphyrin-IX from protoporphyrinogen-IX	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00142	iminoaspartate from L-aspartate (oxidase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00143	quinolinate from L-kynurenine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00144	nicotinate D-ribonucleotide from quinolinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00145	NAD(+) from deamido-NAD(+) (ammonia route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00146	NAD(+) from deamido-NAD(+) (L-Gln route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00147	AMP from IMP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00148	acetoacetate and fumarate from L-phenylalanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00149	L-arogenate from prephenate (L-Asp route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00150	L-arogenate from prephenate (L-Glu route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00151	L-phenylalanine from L-arogenate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00152	phenylpyruvate from prephenate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00153	L-phenylalanine from phenylpyruvate (PDH route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00154	L-phenylalanine from phenylpyruvate (ArAT route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00157	pimeloyl-CoA from pimelate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00158	CoA from (R)-pantothenate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00159	L-proline from L-ornithine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00160	L-glutamate 5-semialdehyde from L-ornithine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00161	L-glutamate 5-semialdehyde from L-glutamate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00162	L-proline from L-glutamate 5-semialdehyde	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00163	N-acetylputrescine from putrescine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00164	carbamoyl phosphate from L-arginine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00165	(S)-3-hydroxy-3-methylglutaryl-CoA from (R)-mevalonate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00166	geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00167	farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00168	CO(2) and NH(3) from urea (urease route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00169	CO(2) and NH(3) from urea (allophanate route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00170	L-glutamate from L-proline	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00171	5-aminolevulinate from glycine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00172	coproporphyrinogen-III from 5-aminolevulinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00173	sirohydrochlorin from precorrin-2	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00174	siroheme from sirohydrochlorin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00175	protoheme from protoporphyrin-IX	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00176	D-xylulose 5-phosphate from L-ascorbate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00177	L-ornithine and urea from L-arginine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00178	L-citrulline from L-ornithine and carbamoyl phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00179	(N(omega)-L-arginino)succinate from L-aspartate and L-citrulline	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00180	L-arginine and fumarate from (N(omega)-L-arginino)succinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00181	betaine from choline	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00182	betaine aldehyde from choline (cytochrome c reductase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00183	betaine from betaine aldehyde	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00184	glycolate from 1,2-dichloroethane	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00185	catechol from benzene	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00186	3-methylcatechol from toluene	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00187	sarcosine from creatinine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00188	2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00189	5-amino-6-(D-ribitylamino)uracil from GTP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00192	FMN from riboflavin (ATP route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00193	FAD from FMN	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00194	D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00195	D-xylulose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00196	D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00197	D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00198	alpha-D-mannose 1-phosphate from D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00199	pyruvate and succinate semialdehyde from 4-hydroxyphenylacetate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00200	glycine from L-allo-threonine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00201	glycine from glyoxylate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00202	acetaldehyde and glycine from L-threonine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00203	betaine aldehyde from choline (monooxygenase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00204	choline from choline sulfate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00205	sarcosine from betaine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00206	formaldehyde and glycine from sarcosine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00207	D-fructose 6-phosphate from D-ribulose 5-phosphate and formaldehyde	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00208	ADP-L-glycero-beta-D-manno-heptose from D-glycero-beta-D-manno-heptose 7-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00209	(S)-reticuline from (S)-norcoclaurine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00210	palmatine from columbamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00211	berbamunine from (R)-N-methylcoclaurine and (S)-N-methylcoclaurine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00212	3alpha(S)-strictosidine from secologanin and tryptamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00213	L-cystathionine from O-acetyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00214	L-homocysteine from O-succinyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00215	(S)-scoulerine from (S)-reticuline	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00216	S-adenosylmethioninamine from S-adenosyl-L-methionine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00217	indole and pyruvate from L-tryptophan	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00218	L-kynurenine from L-tryptophan	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00219	L-alanine and anthranilate from L-kynurenine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00220	iminoaspartate from L-aspartate (dehydrogenase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00221	quinolinate from iminoaspartate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00222	deamido-NAD(+) from nicotinate D-ribonucleotide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00223	nicotinate D-ribonucleotide from nicotinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00224	acetyl-CoA from acetate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00227	LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate (aminotransferase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00228	D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00229	lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00230	KDO(2)-lipid A from CMP-3-deoxy-D-manno-octulosonate and lipid IV(A)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00231	6-hydroxypseudooxynicotine from nicotine (R-isomer route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00232	UDP-4-deoxy-4-formamido-beta-L-arabinose from UDP-alpha-D-glucuronate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00233	4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate from UDP-4-deoxy-4-formamido-beta-L-arabinose and undecaprenyl phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00234	UDP-alpha-D-glucuronate from UDP-alpha-D-glucose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00235	D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate from sedoheptulose 7-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00236	D-alanine from L-alanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00237	NH(3) and pyruvate from D-alanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00238	cyanurate from atrazine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00239	biuret from cyanurate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00240	phosphatidylglycerol from CDP-diacylglycerol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00241	glycine from L-threonine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00242	propanoate from L-threonine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00243	CDP-3,6-dideoxy-D-mannose from CTP and alpha-D-glucose 1-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00244	alpha-ribazole from 5,6-dimethylbenzimidazole	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00245	D-glyceraldehyde 3-phosphate and pyruvate from D-galactonate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00246	vindoline from tabersonine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00247	alpha-D-glucosamine 6-phosphate from D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00248	N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route I)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00249	N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00250	UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00251	D-glucose from alpha,alpha-trehalose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00252	hypotaurine from 2-aminoethanethiol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00253	hypotaurine from L-cysteine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00254	taurine from hypotaurine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00255	taurine from L-cysteine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00256	aminoacetaldehyde and sulfite from taurine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00257	acetyl phosphate and sulfite from taurine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00258	sucrose from D-fructose 6-phosphate and UDP-alpha-D-glucose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00259	3,4',5-trihydroxystilbene from trans-4-coumarate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00260	N-formimidoyl-L-glutamate from L-histidine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00261	L-glutamate from N-formimidoyl-L-glutamate (hydrolase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00262	L-glutamate from N-formimidoyl-L-glutamate (deiminase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00263	L-glutamate from N-formimidoyl-L-glutamate (transferase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00264	staphyloxanthin from farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00265	ethylene from S-adenosyl-L-methionine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00266	geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00267	2-dehydro-3-deoxy-L-arabinonate from L-arabinose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00268	glycolaldehyde and pyruvate from 2-dehydro-3-deoxy-L-arabinonate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00269	2-oxoglutarate from 2-dehydro-3-deoxy-L-arabinonate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00270	D-xylulose 5-phosphate from L-arabinose (fungal route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00271	creatine from L-arginine and glycine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00272	pentalenene from farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00273	aristolochene from farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00274	germacradienol from farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00275	germacrene D from farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00276	NH(3) and pyruvate from L-alanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00277	pyruvate from L-alanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00278	betaine aldehyde from choline (dehydrogenase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00279	4-pyridoxate from pyridoxal	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00280	pyridoxal from pyridoxine (oxidase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00281	protein N(6)-(lipoyl)lysine from lipoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00282	protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00283	thiamine diphosphate from thiamine phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00284	thiamine phosphate from thiamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00285	thiamine diphosphate from thiamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00286	CO(2) and formate from oxalate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00287	NAD(+) from nicotinamide D-ribonucleotide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00288	glycerone phosphate from L-rhamnose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00289	lactose 6-phosphate from lactose (PTS route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00290	D-galactose 6-phosphate and beta-D-glucose from lactose 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00291	GDP-D-glycero-alpha-D-manno-heptose from D-glycero-alpha-D-manno-heptose 7-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00292	cyclic 2,3-diphosphoglycerate from 2-phospho-D-glycerate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00293	(S)-lactate from pyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00294	CDP-diacylglycerol from sn-glycerol 3-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00295	phosphatidylethanolamine from CDP-diacylglycerol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00296	acetate and pyruvate from L-glutamate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00297	formate from formaldehyde (glutathione route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00298	L-lactaldehyde and glycerone phosphate from L-fucose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00299	2,5-dioxopentanoate from D-glucarate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00300	D-glycerate from galactarate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00301	uridine from cytidine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00302	uracil from uridine (phosphorylase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00303	uracil from uridine (hydrolase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00304	UMP from uracil	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00305	UMP from uridine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00306	dTMP from thymine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00307	CTP from cytidine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00308	malonate and urea from uracil	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00309	AMP from adenine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00310	IMP from inosine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00311	IMP from hypoxanthine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00312	AMP from ADP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00313	(S)-allantoin from urate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00314	allantoate from (S)-allantoin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00315	(S)-ureidoglycolate from allantoate (aminidohydrolase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00316	(S)-ureidoglycolate from allantoate (amidohydrolase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00317	glyoxylate from (S)-ureidoglycolate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00318	oxalurate from (S)-ureidoglycolate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00319	XMP from xanthine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00320	AMP from adenosine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00321	xanthine from guanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00322	urate from hypoxanthine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00323	IMP from AMP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00324	phosphatidate from CDP-diacylglycerol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00325	dUMP from dCTP (dUTP route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00326	dUMP from dCTP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00327	glycerone phosphate from glycerol (oxidative route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00328	propane-1,3-diol from glycerol (reductive route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00329	sn-glycerol 3-phosphate from glycerol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00330	glycerone phosphate from sn-glycerol 3-phosphate (anaerobic route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00331	glycerone phosphate from sn-glycerol 3-phosphate (aerobic route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00332	(R)-lactate from methylglyoxal	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00333	(R,R)-butane-2,3-diol from pyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00334	D-fructose 6-phosphate from N-acetylneuraminate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00335	crotonoyl-CoA from L-glutamate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00336	L-glutamate from 2-oxoglutarate and L-glutamine (NADP(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00337	L-glutamate from 2-oxoglutarate and L-glutamine (NAD(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00338	L-glutamate from 2-oxoglutarate and L-glutamine (ferredoxin route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00339	5,10-methenyl-5,6,7,8-tetrahydromethanopterin from CO(2)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00340	5,10-methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8-tetrahydromethanopterin (coenzyme F420 route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00341	5,10-methylene-5,6,7,8-tetrahydromethanopterin from 5,10-methenyl-5,6,7,8-tetrahydromethanopterin (hydrogen route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00342	methyl-coenzyme M from 5,10-methylene-5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00343	methane from methyl-coenzyme M	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00344	coenzyme B and coenzyme M from coenzyme M-coenzyme B heterodisulfide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00345	formate from formaldehyde (H(4)MPT route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00346	uracil from cytosine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00347	dinitrogen from nitrate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00348	acetyl-CoA from malonyl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00349	malonyl-CoA from acetyl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00350	heme A from heme O	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00351	D-tagatose 6-phosphate from D-galactose 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00352	isocitrate from oxaloacetate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00353	(S)-malate from isocitrate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00354	oxaloacetate from (S)-malate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00355	D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00356	phenylacetate from L-phenylalanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00357	trans-cinnamate from L-phenylalanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00358	kynurenate from L-kynurenine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00359	3,4-dihydroxybenzoate from phthalate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00360	1,3-diaminopropane from L-aspartate 4-semialdehyde	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00361	dopamine from L-tyrosine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00362	(R)-noradrenaline from dopamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00363	(R)-adrenaline from (R)-noradrenaline	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00364	phosphocholine from choline	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00365	phosphocholine from phosphoethanolamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00366	phosphatidylcholine from phosphocholine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00367	phosphatidylethanolamine from ethanolamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00368	dhurrin from L-tyrosine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00369	AMP from 3',5'-cyclic AMP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00370	GMP from 3',5'-cyclic GMP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00371	5-valerolactone from cyclopentanol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00372	lanosterol from farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00373	zymosterol from lanosterol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00374	ergosterol from zymosterol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00375	dehydro-D-arabinono-1,4-lactone from D-arabinose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00376	acetate from ethanol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00377	D-glucose 6-phosphate and lysine from fructoselysine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00378	UDP-alpha-D-xylose from UDP-alpha-D-glucuronate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00379	UDP-L-arabinose from UDP-alpha-D-xylose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00380	all-trans-phytoene from geranylgeranyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00381	capsanthin from antheraxanthin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00382	capsorubin from violaxanthin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00383	2-hydroxy-2,4-pentadienoate and salicylate from dibenzofuran	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00384	2-hydroxymuconate and catechol from dibenzo-p-dioxin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00385	D-sorbitol 6-phosphate from D-sorbitol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00386	D-fructose 6-phosphate from D-sorbitol 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00387	D-sorbitol from D-fructose and D-glucose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00388	D-gluconate from D-glucono-1,5-lactone	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00389	histamine from L-histidine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00390	myo-inositol from D-glucose 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00391	trans-4-coumarate from trans-cinnamate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00392	nicotinate from nicotinamide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00393	heme O from protoheme	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00394	3-(2,3-dihydroxyphenyl)propanoate from 3-(3-hydroxyphenyl)propanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00395	3-(2,3-dihydroxyphenyl)propanoate from 3-phenylpropanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00396	acetaldehyde and pyruvate from 3-(2,3-dihydroxyphenyl)propanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00397	acetyl-CoA from acetaldehyde	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00398	serotonin from L-tryptophan	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00399	2-hydroxy-3-oxosuccinate from L-tartrate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00400	2-hydroxy-3-oxosuccinate from meso-tartrate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00401	D-glycerate from 2-hydroxy-3-oxosuccinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00402	D-glycerate from L-tartrate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00403	3-hydroxypyruvate from D-glycerate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00404	4-amino-5-hydroxymethyl-2-methylpyrimidine and 5-(2-hydroxyethyl)-4-methylthiazole from thiamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00405	taxa-4(20),11-dien-5alpha-ol from geranylgeranyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00406	10-deacetyl-2-debenzoylbaccatin III from taxa-4(20),11-dien-5alpha-ol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00407	baccatin III from 10-deacetyl-2-debenzoylbaccatin III	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00408	taxol from baccatin III	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00409	melatonin from serotonin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00410	7,8-dihydroneopterin triphosphate from GTP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00411	5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00412	7,8-dihydrofolate from folate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00413	tetrahydrobiopterin from 7,8-dihydroneopterin triphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00414	tetrahydrobiopterin from biopterin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00415	2-dehydro-3-deoxy-D-gluconate from pectin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00416	D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-gluconate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00417	3-phospho-D-glycerate from glycolate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00418	glycolate from 2-phosphoglycolate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00419	glutaryl-CoA from L-lysine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00420	glutarate from L-lysine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00421	2,4-dihydroxy-1,4-benzoxazin-3-one from indoleglycerol phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00422	benzoate from (R)-mandelate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00423	tetrahydrobiopterin from dihydrobiopterin	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00424	4-methyl-2-oxopentanoate from L-leucine (aminotransferase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00425	4-methyl-2-oxopentanoate from L-leucine (dehydrogenase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00426	3-isovaleryl-CoA from 4-methyl-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00427	(S)-3-hydroxy-3-methylglutaryl-CoA from 3-isovaleryl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00428	(1S,4R)-1-hydroxylimonen-2-one from (4R)-limonene	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00429	(1R,4S)-isodihydrocarvone from (4R)-limonene	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00430	formaldehyde from methylamine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00431	acetoacetate from (S)-3-hydroxy-3-methylglutaryl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00432	S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (hydrolase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00433	S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00434	L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00435	4-aminobutanoate from putrescine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00436	ppGpp from GTP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00437	ppGpp from GDP	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00438	GMP from guanine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00439	D-ribose 5-phosphate from beta-D-ribopyranose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00440	nicotinamide D-ribonucleotide from 5-phospho-alpha-D-ribose 1-diphosphate and nicotinamide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00441	formate from pyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00442	stachyose from raffinose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00443	formaldehyde from methanol	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00444	acetoacetyl-CoA from succinyl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00445	L-seryl-tRNA(Sec) from L-serine and tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00446	selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (archaeal/eukaryal route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00447	selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00448	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00449	acetaldehyde and pyruvate from p-cumate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00450	succinyl-CoA from propanoyl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00451	glycine from 2-phosphoglycolate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00452	3-phospho-D-glycerate from glycine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00453	6-hydroxypseudooxynicotine from nicotine (S-isomer route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00454	2,6-dihydroxypyridine and 4-(methylamino)butanoate from 6-hydroxypseudooxynicotine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00455	2-deoxystreptamine from D-glucose 6-phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00456	(4S)-limonene from geranyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00457	(4R)-limonene from geranyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00458	(-)-alpha-pinene from geranyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00459	(-)-beta-pinene from geranyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00460	FMN from riboflavin (CTP route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00462	GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GTP route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00463	GDP-alpha-D-mannose from alpha-D-mannose 1-phosphate (GDP route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00464	L-ascorbate from GDP-alpha-D-mannose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00465	L-ascorbate from UDP-alpha-D-glucuronate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00466	phosphatidylcholine from choline	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00467	CO(2) and NH(3) from carbamoyl phosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00468	putrescine from N-carbamoylputrescine (amidase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00469	putrescine from N-carbamoylputrescine (transferase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00470	5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00471	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (carboxylase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00472	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00473	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00474	8-amino-7-oxononanoate from pimeloyl-CoA	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00475	7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00476	7,8-diaminononanoate from 8-amino-7-oxononanoate (Lys route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00477	biotin from 7,8-diaminononanoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00478	(S)-dihydroorotate from bicarbonate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00479	orotate from (S)-dihydroorotate (O2 route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00480	orotate from (S)-dihydroorotate (NAD(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00481	orotate from (S)-dihydroorotate (quinone route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00482	UMP from orotate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00483	(4-hydroxyphenyl)pyruvate from prephenate (NAD(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00484	(4-hydroxyphenyl)pyruvate from prephenate (NADP(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00485	L-tyrosine from (4-hydroxyphenyl)pyruvate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00486	L-tyrosine from L-arogenate (NAD(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00487	L-tyrosine from L-arogenate (NADP(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00488	2-oxoglutarate from isocitrate (NADP(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00489	2-oxoglutarate from isocitrate (NAD(+) route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00490	succinyl-CoA from 2-oxoglutarate (dehydrogenase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00491	succinyl-CoA from 2-oxoglutarate (synthase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00492	succinate from succinyl-CoA (ligase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00493	succinate from succinyl-CoA (transferase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00494	succinate from 2-oxoglutarate (transferase route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00495	fumarate from succinate (bacterial route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00496	fumarate from succinate (eukaryal route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00497	(S)-malate from fumarate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00498	oxaloacetate from (S)-malate (quinone route)	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00499	riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00500	beta-D-fructofuranosyl alpha-D-mannopyranoside from D-fructose 6-phosphate and GDP-alpha-D-mannose	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00501	6-hydroxynicotinate from nicotinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00502	propanoate and pyruvate from 6-hydroxynicotinate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00503	4-hydroxybenzoate from 4-chlorobenzoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00504	glycine from L-serine	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00505	L-aspartate from oxaloacetate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00506	L-glutamine from L-glutamate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00507	catechol from anthranilate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00508	15-cis-phytoene from geranylgeranyl diphosphate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00509	1,4-dihydroxy-2-naphthoate from chorismate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_ULS00510	menaquinol from 1,4-dihydroxy-2-naphthoate	http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway		
http://purl.obolibrary.org/obo/UPa_UPA00809	dibenzo-p-dioxin degradation	http://purl.obolibrary.org/obo/UPa_UPA00706	aromatic compound degradation		Degradation of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxin is created as by-products during industrial processes such as incineration, paper bleaching, and chemical synthesis.
http://purl.obolibrary.org/obo/UPa_UPA00812	D-sorbitol degradation	http://purl.obolibrary.org/obo/UPa_UPA00612	alcohol degradation		Degradation of sorbitol, one of the ten stereoisomeric hexitols.
http://purl.obolibrary.org/obo/UPa_UPA00814	D-gluconate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00813	aldonic acid biosynthesis		Biosynthesis of D-gluconic acid, an aldonic acid.
http://purl.obolibrary.org/obo/UPa_UPA00815	D-sorbitol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00622	alcohol biosynthesis		Biosynthesis of sorbitol, one of the ten stereoisomeric hexitols.
http://purl.obolibrary.org/obo/UPa_UPA00822	histamine biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00490	histidine metabolism		Biosynthesis of histamine (2-(4-imidazolyl)ethylamine). This physiologically active amine is derived from the decarboxylation of the amino-acid histidine, a reaction catalyzed by the enzyme L-histidine decarboxylase.
http://purl.obolibrary.org/obo/UPa_UPA00823	myo-inositol biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00914	myo-inositol metabolism		Biosynthesis of myo-inositol (cis-1,2,3,5-trans-4,6-cyclohexanehexol), arbocyclic polyol that plays an important role as the structural basis for a number of secondary messengers in eukaryotic cells, including inositol phosphates, phosphatidylinositol (PI) and phosphatidylinositol phosphate (PIP) lipids.
http://purl.obolibrary.org/obo/UPa_UPA00825	trans-4-coumarate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00711	phenylpropanoid biosynthesis		Biosynthesis of 4-coumaric acid (trans-4-hydroxycinnamic acid), a phenylpropanoid compound.
http://purl.obolibrary.org/obo/UPa_UPA00830	nicotinate biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA01009	nicotinate metabolism		Biosynthesis of nicotinic acid, also known as niacin or vitamin B3, a water-soluble vitamin.
http://purl.obolibrary.org/obo/UPa_UPA00834	heme O biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00678	porphyrin-containing compound biosynthesis		Biosynthesis of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle. Heme O is a precursor in heme A biosyntesis. Warning: the biochemical reactions composing this pathway are not yet clearly defined.
http://purl.obolibrary.org/obo/UPa_UPA00839	tartrate degradation	http://purl.obolibrary.org/obo/UPa_UPA00794	aldaric acid degradation		Degradation of tartrate, an aldaric acid that occurs naturally in many plants, particularly grapes, bananas, and tamarinds, and is one of the main acids found in wine.
http://purl.obolibrary.org/obo/UPa_UPA00846	serotonin biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00754	aromatic compound biosynthesis		Biosynthesis of serotonin (5-hydroxytryptamine, or 5-HT), a monoamine neurotransmitter. Serotonin is synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables. In plants, serotonin is implicated in several physiological roles such as flowering, morphogenesis, and adaptation to environmental changes.
http://purl.obolibrary.org/obo/UPa_UPA00999	pimeloyl-CoA biosynthesis	http://purl.obolibrary.org/obo/UPa_UPA00415	metabolic intermediate biosynthesis		Biosynthesis of 6-carboxyhexanoyl-CoA (pimeloyl-CoA), a precursor of biotin in some organisms.
http://purl.obolibrary.org/obo/UPa_UPA01009	nicotinate metabolism	http://purl.obolibrary.org/obo/UPa_UPA00398	cofactor metabolism		Metabolism of nicotinic acid, also known as niacin or vitamin B3, a water-soluble vitamin.
http://purl.obolibrary.org/obo/UPa_UPC00001	H(2)O	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00002	ATP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00003	NAD(+)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00004	NADH	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00005	NADPH	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00006	NADP(+)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00007	O(2)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00008	ADP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00009	phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00010	CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00011	CO(2)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00013	diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00014	NH(3)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00015	UDP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00016	FAD	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00018	pyridoxal 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00019	S-adenosyl-L-methionine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00020	AMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00021	S-adenosyl-L-homocysteine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00022	pyruvate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00024	acetyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00025	L-glutamate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00026	2-oxoglutarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00027	H(2)O(2)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00028	acceptor	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00029	UDP-alpha-D-glucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00030	reduced acceptor	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00031	D-glucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00032	protoheme	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00033	acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00035	GDP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00036	oxaloacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00037	glycine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00040	acyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00041	L-alanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00042	succinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00043	UDP-N-acetyl-alpha-D-glucosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00044	GTP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00047	L-lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00048	glyoxylate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00049	L-aspartate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00051	glutathione	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00053	3'-phospho-5'-adenylyl sulfate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00054	adenosine 3',5'-bisphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00055	CMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00058	formate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00059	sulfate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00061	FMN	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00062	L-arginine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00063	CTP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00064	L-glutamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00065	L-serine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00067	formaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00068	thiamine diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00072	L-ascorbate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00073	L-methionine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00074	phosphoenolpyruvate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00075	UTP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00077	L-ornithine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00078	L-tryptophan	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00079	L-phenylalanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00080	H(+)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00082	L-tyrosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00083	malonyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00084	acetaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00085	D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00086	urea	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00088	nitrite	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00089	sucrose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00090	catechol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00091	succinyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00092	D-glucose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00093	sn-glycerol 3-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00094	sulfite	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00095	D-fructose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00096	GDP-alpha-D-mannose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00097	L-cysteine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00099	beta-alanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00100	propanoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00101	5,6,7,8-tetrahydrofolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00103	alpha-D-glucose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00105	UMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00106	uracil	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00108	anthranilate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00109	2-oxobutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00111	glycerone phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00112	CDP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00113	pyrroloquinoline quinone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00114	choline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00116	glycerol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00117	D-ribose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00118	D-glyceraldehyde 3-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00119	5-phospho-alpha-D-ribose 1-diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00120	biotin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00121	D-ribose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00122	fumarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00123	L-leucine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00125	ferricytochrome c	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00126	ferrocytochrome c	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00129	isopentenyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00130	IMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00132	methanol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00133	D-alanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00134	putrescine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00135	L-histidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00137	myo-inositol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00138	reduced ferredoxin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00139	oxidized ferredoxin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00141	3-methyl-2-oxobutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00143	5,10-methylene-THF	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00144	GMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00147	adenine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00148	L-proline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00149	(S)-malate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00152	L-asparagine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00153	nicotinamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00155	L-homocysteine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00156	4-hydroxybenzoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00157	phosphatidylcholine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00158	citrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00160	glycolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00163	propanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00164	acetoacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00166	phenylpyruvate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00167	UDP-alpha-D-glucuronate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00168	3-hydroxypyruvate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00169	carbamoyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00170	S-methyl-5'-thioadenosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00175	Co(2+)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00177	hydrogen cyanide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00178	thymine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00179	agmatine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00180	benzoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00183	L-valine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00184	glycerone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00186	(S)-lactate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00188	L-threonine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00189	ethanolamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00190	UDP-alpha-D-xylose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00191	D-glucuronate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00194	adenosylcobalamin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00197	3-phospho-D-glycerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00198	D-glucono-1,5-lactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00199	D-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00204	2-dehydro-3-deoxy-D-gluconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00209	oxalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00212	adenosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00213	sarcosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00214	thymidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00216	D-arabinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00218	methylamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00221	beta-D-glucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00222	3-oxopropanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00223	4-coumaroyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00224	5'-adenylyl sulfate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00227	acetyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00229	acyl-carrier protein	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00230	3,4-dihydroxybenzoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00231	D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00232	succinate semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00233	4-methyl-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00234	10-formyl-5,6,7,8-tetrahydrofolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00235	dimethylallyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00236	3-phospho-D-glyceroyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00242	guanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00243	lactose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00244	nitrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00245	taurine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00250	pyridoxal	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00251	chorismate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00253	nicotinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00254	prephenate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00255	riboflavin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00256	(R)-lactate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00257	D-gluconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00258	D-glycerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00259	L-arabinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00261	benzaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00262	hypoxanthine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00263	L-homoserine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00266	glycolaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00268	dihydrobiopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00269	CDP-diacylglycerol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00270	N-acetylneuraminate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00272	tetrahydrobiopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00275	D-mannose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00279	D-erythrose 4-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00282	H(2)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00283	hydrogen sulfide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00288	bicarbonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00294	inosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00295	orotate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00296	D-quinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00299	uridine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00300	creatine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00307	CDP-choline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00310	D-xylulose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00311	isocitrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00312	L-xylulose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00313	oxalyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00314	pyridoxine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00315	spermidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00322	2-oxoadipate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00325	GDP-L-fucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00327	L-citrulline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00328	L-kynurenine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00332	acetoacetyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00334	4-aminobutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00337	(S)-dihydroorotate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00341	geranyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00342	thioredoxin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00343	thioredoxin disulfide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00344	phosphatidylglycerol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00345	6-phospho-D-gluconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00346	phosphoethanolamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00350	phosphatidylethanolamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00352	alpha-D-glucosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00353	geranylgeranyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00354	D-fructose 1,6-bisphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00355	L-dopa	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00356	(S)-3-hydroxy-3-methylglutaryl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00357	N-acetyl-D-glucosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00364	dTMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00365	dUMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00366	urate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00378	thiamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00379	xylitol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00380	cytosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00383	malonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00385	xanthine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00388	histamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00398	tryptamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00407	L-isoleucine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00415	7,8-dihydrofolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00416	phosphatidate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00417	cis-aconitate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00418	(R)-mevalonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00423	trans-cinnamate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00424	L-lactaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00430	5-aminolevulinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00431	5-aminopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00433	2,5-dioxopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00436	N-carbamoylputrescine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00437	N(2)-acetyl-L-ornithine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00438	N-carbamoyl-L-aspartate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00439	N-formimidoyl-L-glutamate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00440	5-methyl-THF	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00441	L-aspartate 4-semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00448	farnesyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00449	saccharopine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00455	nicotinamide D-ribonucleotide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00458	dCTP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00460	dUTP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00463	indole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00469	ethanol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00470	pectate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00475	cytidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00488	formamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00489	glutarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00492	raffinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00493	shikimate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00499	allantoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00501	CDP-glucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00504	folate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00506	L-cysteate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00507	L-rhamnose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00508	L-ribulose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00512	benzoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00519	hypotaurine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00521	(4S)-limonene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00522	(R)-pantoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00527	glutaryl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00532	L-arabinitol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00533	nitric oxide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00534	pyridoxamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00536	triphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00544	homogentisate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00545	L-arabinonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00546	methylglyoxal	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00547	(R)-noradrenaline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00552	meso-tartrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00555	4-aminobutanal	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00557	cyclopentanone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00568	4-aminobenzoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00570	CDP-ethanolamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00575	3',5'-cyclic AMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00576	betaine aldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00581	guanidinoacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00582	phenylacetyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00588	phosphocholine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00593	sulfoacetaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00596	2-hydroxy-2,4-pentadienoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00601	phenylacetaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00603	(S)-ureidoglycolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00606	3-sulfino-L-alanine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00615	protein-L-histidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00620	alpha-D-ribose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00624	N-acetyl-L-glutamate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00627	pyridoxine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00631	2-phospho-D-glycerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00632	3-hydroxyanthranilate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00636	alpha-D-mannose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00641	1,2-diacyl-sn-glycerol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00642	4-hydroxyphenylacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00643	5-hydroxy-L-tryptophan	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00645	N-acetyl-D-mannosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00647	pyridoxamine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00652	D-arabinono-1,4-lactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00655	XMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00664	5-formiminotetrahydrofolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00666	LL-2,6-diaminopimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00669	L-gamma-glutamyl-L-cysteine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00671	(S)-3-methyl-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00672	2-deoxy-alpha-D-ribose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00673	2-deoxy-D-ribose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00679	5-dehydro-4-deoxy-D-glucarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00680	DL-2,6-diaminopimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00681	1-acyl-sn-glycerol 3-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00683	(S)-methylmalonyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00684	2-dehydro-3-deoxy-L-arabinonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00691	scyllo-inosose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00697	dinitrogen	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00698	chloride	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00714	pectin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00719	betaine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00725	lipoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00748	siroheme	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00750	spermine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00751	squalene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00780	serotonin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00785	trans-urocanate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00788	(R)-adrenaline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00791	creatinine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00794	D-sorbitol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00797	ethylamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00798	formyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00800	L-gulonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00802	oxalurate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00805	salicylate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00810	(R)-acetoin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00811	trans-4-coumarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00813	barbiturate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00818	D-glucarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00826	L-arogenate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00846	3-oxoadipate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00847	4-pyridoxate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00857	deamido-NAD(+)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00860	L-histidinol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00861	L-rhamnulose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00862	methanofuran	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00864	(R)-pantothenate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00876	coenzyme F420	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00877	crotonoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00879	galactarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00880	D-galactonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00882	3'-dephospho-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00885	isochorismate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00887	nitrous oxide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00898	L-tartrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00919	choline sulfate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00921	7,8-dihydropteroate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00922	dimethylmaleate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00931	porphobilinogen	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00935	UDP-L-arabinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00940	2-oxoglutaramate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00942	3',5'-cyclic GMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00944	3-dehydroquinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00956	L-alpha-aminoadipate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00966	2-dehydropantoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00969	3-hydroxypropanal	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00971	4-pyridoxolactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00978	N-acetylserotonin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00979	O-acetyl-L-serine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00986	1,3-diaminopropane	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC00988	2-phosphoglycolate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01001	N-formylmethanofuran	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01005	O-phospho-L-serine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01010	urea-1-carboxylate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01019	L-fucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01020	6-hydroxynicotinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01024	hydroxymethylbilane	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01026	N,N-dimethylglycine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01031	S-formylglutathione	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01036	4-maleylacetoacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01037	7,8-diaminononanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01040	L-gulono-1,4-lactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01043	N-carbamoylsarcosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01045	N-formyl-L-glutamate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01051	uroporphyrinogen III	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01054	(S)-2,3-epoxysqualene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01056	(S)-6-hydroxynicotine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01061	4-fumarylacetoacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01063	pimeloyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01077	O-acetyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01079	protoporphyrinogen-IX	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01080	1,5-dihydro-coenzyme F(420)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01081	thiamine phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01083	alpha,alpha-trehalose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01091	deacetylvindoline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01092	8-amino-7-oxononanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01096	D-sorbitol 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01097	D-tagatose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01099	L-fuculose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01100	L-histidinol phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01101	L-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01102	O-phospho-L-homoserine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01103	orotidine 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01107	(R)-5-phosphomevalonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01112	D-arabinose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01113	D-galactose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01114	L-arabinono-1,4-lactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01115	L-Galactono-1,4-lactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01118	O-succinyl-L-homoserine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01131	L-rhamnulose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01134	pantotheine 4'-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01137	S-adenosylmethioninamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01143	(R)-5-diphosphomevalonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01146	2-hydroxy-3-oxopropanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01151	D-ribose 1,5-bisphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01159	2,3-bisphospho-D-glycerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01161	(3,4-dihydroxyphenyl)acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01163	3-carboxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01165	L-glutamate 5-semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01179	(4-hydroxyphenyl)pyruvate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01180	4-methylthio-2-oxobutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01185	nicotinate D-ribonucleotide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01187	3-deoxy-D-manno-octulosonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01210	N-methylethanolamine phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01213	(R)-methylmalonyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01216	2-dehydro-3-deoxy-D-galactonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01217	5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01219	CDP-4-dehydro-6-deoxy-D-glucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01222	GDP-4-dehydro-6-deoxy-D-mannose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01228	ppGpp	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01234	1-aminocyclopropanecarboxylate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01235	1-alpha-D-galactosyl-myo-inositol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01236	D-glucono-1,5-lactone 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01250	N-acetyl-L-glutamate 5-semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01251	(R)-homocitrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01252	4-(2-aminophenyl)-2,4-dioxobutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01267	imidazole-acetol phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01268	5-amino-6-(5-phosphoribosylamino)uracil	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01269	5-O-(1-carboxyvinyl)-3-phosphoshikimate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01273	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01274	N(5)-formyl-5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01278	2-carboxy-2,5-dihydro-5-oxofuran-2-acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01279	4-amino-5-hydroxymethyl-2-methylpyrimidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01286	6-phospho-2-dehydro-3-deoxy-D-galactonic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01297	6-hydroxypseudooxynicotine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01300	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01302	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01304	2,5-diamino-4-hydroxy-6-(5-phosphoribosylamino)pyrimidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01327	HCl	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01352	FADH2	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01359	pyrroloquinoline quinol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01407	benzene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01438	methane	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01455	toluene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01598	melatonin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01606	phthalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01613	stachyose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01626	vindoline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01641	tRNA(Glu)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01678	2-aminoethanethiol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01694	ergosterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01717	kynurenate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01721	L-fuculose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01724	lanosterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01732	mesaconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01795	columbamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01825	alpha-L-galactose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01841	pentalenene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01847	FMNH(2)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01852	secologanin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01909	dethiobiotin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01983	(R)-mandelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC01984	(S)-mandelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02004	aristolochene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02020	cyclopentanol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02091	2-ureidoglycine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02105	(S)-reticuline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02106	(S)-scoulerine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02137	phenylglyoxylate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02191	protoporphyrin-IX	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02222	maleylacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02226	2-methylmaleate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02232	3-oxoadipyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02240	5-valerolactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02280	GDP-L-galactose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02291	L-cystathionine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02295	2-methylene-3-methylsuccinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02350	(S)-allantoin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02370	4-chlorobenzoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02411	glutaconyl-1-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02457	propane-1,3-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02463	precorrin-2	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02480	cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02501	2-hydroxymuconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02504	(2S)-2-isopropylmalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02526	biphenyl-2,3-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02565	N-methylhydantoin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02591	sucrose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02612	(R)-citramalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02614	L-citramalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02627	2-deoxystreptamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02630	2-hydroxyglutarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02631	2-isopropylmaleate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02632	2-methylpropanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02637	3-dehydroshikimate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02656	pimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02673	desacetoxyvindoline	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02700	N-formyl-N-kynurenine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02714	N-acetylputrescine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02727	N(6)-acetyl-L-lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02730	2-succinylbenzoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02737	phosphatidylserine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02739	1-(5-phospho-D-ribosyl)-ATP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02741	1-(5-phosphoribosyl)-5'-AMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02814	benzene-1,2,4-triol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02876	propanoyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02923	3-methylcatechol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02930	2-methyleneglutarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02939	3-isovaleryl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02949	4-hydroxybenzoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC02987	L-glutamyl-tRNA(Glu)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03043	(R)-6-hydroxynicotine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03044	(R,R)-butane-2,3-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03056	2,6-dihydroxypyridine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03058	2-hydroxyglutaryl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03069	3-methylcrotonyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03082	4-phospho-L-aspartate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03087	5-acetamidopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03089	5-methylthio-alpha-D-ribose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03090	5-phospho-beta-D-ribosylamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03114	5,6-dimethylbenzimidazole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03160	2-succinylbenzoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03175	3-phosphoshikimate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03194	(R)-1-aminopropan-2-ol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03227	3-hydroxy-L-kynurenine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03231	3-methylglutaconyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03232	3-phosphohydroxypyruvate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03233	4,5-dihydroxyphthalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03263	coproporphyrinogen-III	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03273	5-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03283	L-2,4-diaminobutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03287	L-glutamyl 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03289	L-xylo-hexulonolactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03291	L-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03296	N(2)-succinyl-L-arginine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03373	5-amino-1-(5-phospho-D-ribosyl)imidazole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03393	4-phospho-D-erythronate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03406	(N(omega)-L-arginino)succinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03415	N(2)-succinyl-L-ornithine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03427	prephytoene diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03451	(R)-S-lactoylglutathione	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03459	2-hydroxy-3-oxosuccinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03470	3alpha(S)-strictosidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03492	(R)-4'-phosphopantothenate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03506	indoleglycerol phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03508	L-2-amino-3-oxobutanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03569	biphenyl-2,2',3-triol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03576	coenzyme M	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03582	3,4',5-trihydroxystilbene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03586	5-oxo-4,5-dihydro-2-furylacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03589	4-hydroxy-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03598	CDP-3,6-dideoxy-D-glucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03599	CDP-3,6-dideoxy-D-mannose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03618	(2S,3S)-3-methyl-L-aspartate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03652	(2R,3S)-2,3-dimethylmalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03657	1,4-dihydroxy-2-naphthoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03676	3-hydroxy-cis,cis-muconate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03680	4-imidazolone-5-propanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03684	6-pyruvoyl-tetrahydropterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03722	quinolinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03741	(S)-4-amino-5-oxopentanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03742	(S)-4-hydroxymandelonitrile	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03758	dopamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03785	D-tagatose 1,6-bisphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03794	N(6)-(1,2-dicarboxyethyl)-AMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03838	N(1)-(5-phospho-D-ribosyl)glycinamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03871	(S)-2-amino-6-oxopimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03892	phosphatidylglycerophosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03912	(S)-1-pyrroline-5-carboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03920	methyl-coenzyme M	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC03972	(S)-tetrahydrodipicolinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04002	homo-cis-aconitate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04006	1D-myo-inositol 3-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04044	3-(2,3-dihydroxyphenyl)propanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04052	5-oxopent-3-ene-1,2,5-tricarboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04053	5-dehydro-4-deoxy-D-glucuronic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04076	L-2-aminoadipate 6-semialdahyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04091	cis-1,2-dihydrobenzene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04121	CMP-3-deoxy-D-manno-octulosonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04133	N-acetyl-L-glutamyl 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04144	tetrahydropteroyltri-L-glutamate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04181	2-oxo-3-hydroxyisovalerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04186	5-carboxymethyl-2-hydroxymuconic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04188	S-methyl-5-thio-alpha-D-ribose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04226	6-hydroxynicotinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04236	3-carboxy-4-methyl-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04244	6-lactoyl-5,6,7,8-tetrahydropterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04253	electron-transferring flavoprotein	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04257	N-acetyl-D-mannosamine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04261	protein N(pi)-phospho-L-histidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04272	(R)-2,3-dihydroxy-3-methylbutanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04287	3D-3,5/4-trihydroxycyclohexane-1,2-dione	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04294	5-(2-hydroxyethyl)-4-methylthiazole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04297	CDP-4-dehydro-3,6-dideoxy-D-glucose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04302	N-(5-phospho-beta-D-ribosyl)anthranilic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04327	4-methyl-5-(2-phosphoethyl)-thiazole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04330	5,10-methenyl-5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04332	6,7-dimethyl-8-(1-D-ribityl)lumazine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04349	3-deoxy-D-glycero-hexo-2,5-diulosonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04352	N-[(R)-4-phosphonopantothenoyl]-L-cysteine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04353	(Z)-(4-hydroxyphenyl)acetaldehyde oxime	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04376	N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04377	5,10-methylene-5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04390	N-acetyl-LL-2,6-diaminopimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04409	2-amino-3-carboxymuconate semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04411	(2R,3S)-3-isopropylmalate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04421	N-succinyl-LL-2,6-diaminopimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04425	S-adenosyl-4-methylthio-2-oxobutanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04442	2-dehydro-3-deoxy-6-phospho-D-gluconic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04454	5-amino-6-(5-phosphoribitylamino)uracil	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04462	L-2-succinylamino-6-oxopimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04478	8-phospho-3-deoxy-D-manno-octulosonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04479	2-hydroxy-6-oxonona-2,4-diene-1,9-dioate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04488	5-methyl-5,6,7,8-tetrahydromethanopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04489	5-methyltetrahydropteroyltri-L-glutamate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04494	guanosine 3'-diphosphate 5'-triphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04501	N-acetyl-alpha-D-glucosamine 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04525	fecosterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04553	3-carboxy-2,5-dihydro-5-oxofuran-2-acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04556	4-amino-2-methyl-5-phosphomethylpyrimidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04570	reduced electron-transferring flavoprotein	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04578	3-hydroxy-16-methoxy-2,3-dihydrotabersonine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04582	S-methyl-5-thio-D-ribulose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04592	(1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04628	coenzyme B	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04640	2-formamido-N(1)-(5-phospho-D-ribosyl)acetamidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04642	5-carboxymethyl-2-hydroxymuconate semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04652	UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04666	D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04677	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04688	(3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein]	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04691	7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04732	5-amino-6-(D-ribitylamino)uracil	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04734	5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04738	UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04751	5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04752	4-amino-2-methyl-5-diphosphomethylpyrimidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04778	alpha-ribazole 5'-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04783	cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04807	2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04823	(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04824	lipid X	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04832	coenzyme M-coenzyme B heterodisulfide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04874	7,8-dihydroneopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04895	7,8-dihydroneopterin triphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04896	5-(5-phospho-D-ribosylaminoformimino)-1-(5-phosphoribosyl)-imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04916	5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04919	lipid IV(A)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC04932	2,3,2',3'-tetrakis(3-hydroxytetradecanoyl)-alpha-D-glucosaminyl-1,6-beta-D-glucosamine 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05103	4-alpha-methylzymosterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05108	14-demethyllanosterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05125	2-hydroxyethyl-ThPP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05143	dhurrin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05172	selenophosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05176	(S)-N-methylcoclaurine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05177	berbamunine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05198	5'-deoxyadenosine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05202	(S)-3'-hydroxy-N-methylcoclaurine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05223	dodecanoyl-[acyl-carrier protein]	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05243	(R)-N-methylcoclaurine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05315	palmatine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05332	2-phenylethylamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05345	beta-D-fructose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05359	e-	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05382	sedoheptulose 7-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05396	lactose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05413	all-trans-phytoene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05421	15-cis-phytoene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05422	L-dehydroascorbate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05437	zymosterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05440	ergosta-5,7,22,24(28)-tetraen-3beta-ol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05519	L-allo-threonine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05528	3-sulfopyruvate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05533	2-oxaloglutaric acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05535	alpha-aminoadipoyl-S-acyl enzyme	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05539	(S)-2-acetamido-6-oxopimelate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05548	6-acetamido-2-oxohexanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05551	penicillin G	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05556	N-[L-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05557	isopenicillin N	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05560	alpha-aminoadipoyl-C6-AMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05600	2-hydroxy-hept-2,4-diene-1,7-dioic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05629	3-phenylpropanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05662	homoisocitrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05752	octanoyl-[acyl-carrier-protein]	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05761	tetradecanoyl-[acp]	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05772	precorrin-3A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05773	cob(III)yrinic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05775	alpha-ribazole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05778	sirohydrochlorin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05817	(1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05819	menaquinol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05840	iminoaspartate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05847	all-trans-polyprenyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05922	formamidopyrimidine nucleoside triphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05923	2,5-diaminopyrimidine nucleoside triphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05925	7,8-dihydroneopterin 3'-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05931	N(2)-succinyl-L-glutamic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC05932	N-succinyl-L-glutamate 5-semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06006	(S)-2-acetyl-2-hydroxybutanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06007	(2R,3R)-2,3-dihydroxy-3-methylpentanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06010	(S)-2-acetolactate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06019	D-arabino-3-hexulose 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06022	UDP-3-O-(3-hydroxytetradecanoyl)-D-glucosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06024	3-deoxy-D-manno-octulosonyl-lipid IV((A))	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06025	di[3-deoxy-D-manno-octulosonyl]-lipid IV(A)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06026	KDO(2)-lipid A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06032	D-erythro-3-methylmalic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06054	(R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06055	4-(phosphonooxy)-L-threonine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06099	(4R)-limonene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06118	4-(4-deoxy-alpha-D-gluc-4-enosyluronic acid)-D-galacturonic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06148	2,5-diamino-6-(5'-triphosphoryl-3',4'-trihydroxy-2'-oxopentyl)-amino-4-oxopyrimidine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06156	alpha-D-glucosamine 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06157	S(8)-glutaryldihydrolipoamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06160	(S)-norcoclaurine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06161	(S)-coclaurine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06189	cyclic 2,3-diphosphoglycerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06201	2,4-dihydroxyhept-2-enedioic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06231	L-ectoine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06251	lauroyl-KDO(2)-lipid IV(A)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06307	(-)-beta-pinene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06308	(-)-alpha-pinene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06313	biopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06316	dehydro-D-arabinono-1,4-lactone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06319	precorrin-6B	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06320	precorrin-6A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06321	(1R,6S)-1,6-dihydroxycyclohexa-2,4-dienecarboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06387	4-chlorobenzoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06397	ADP-D-glycero-beta-D-manno-heptose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06398	ADP-L-glycero-beta-D-manno-heptose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06399	hydrogenobyrinic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06406	precorrin-3B	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06407	precorrin-4	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06408	precorrin-8X	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06416	precorrin-5	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06442	N(4)-acetyl-L-2,4-diaminobutyric acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06481	L-seryl-tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06482	selenocysteinyl-tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06503	hydrogenobyrinic acid a,c-diamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06504	cob(II)yrinate a,c-diamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06505	cob(I)yrinic acid a,c-diamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06506	adenosylcob(III)yrinic acid a,c-diamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06507	adenosylcobyrinic acid a,c-diamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06508	adenosylcobinamide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06509	adenosylcobinamide phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06510	adenosylcobinamide-GDP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06547	ethylene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06551	atrazine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06552	hydroxyatrazine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06553	N-isopropylammelide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06554	cyanurate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06555	biuret	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06578	p-cumate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06579	cis-2,3-dihydroxy-2,3-dihydro-p-cumic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06580	2,3-dihydroxy-p-cumic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06581	2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06582	2-hydroxy-6-oxo-7-methylocta-2,4-dienoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06588	biphenyl	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06589	cis-3-phenylcyclohexa-3,5-diene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06655	N(2)-(2-carboxyethyl)-L-arginine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06656	deoxyamidinoproclavaminic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06657	amidinoproclavaminic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06658	proclavaminic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06659	dihydroclavaminic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06660	clavaminate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06661	clavulanate-9-aldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06662	clavulanate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06735	aminoacetaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06748	isopropylamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06752	1,2-dichloroethane	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06753	2-chloroethanol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06754	chloroacetaldehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06755	chloroacetic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06892	2-deoxy-5-keto-D-gluconic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC06893	6-phospho-5-dehydro-2-deoxy-D-gluconic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07086	phenylacetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07271	(4R)-limonene 1,2-epoxide	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07276	(1S,2S,4R)-limonene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07335	2-amino-3-oxo-4-phosphonooxybutyrate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07394	taxol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07729	dibenzofuran	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07731	2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07732	dibenzo-p-dioxin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07733	2,2',3-trihydroxy-diphenyl ether	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07734	2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07836	D-glycero-beta-D-manno-heptose 7-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC07838	D-glycero-beta-D-manno-heptose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08353	beta-D-ribopyranose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08579	antheraxanthin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08584	capsanthin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08585	capsorubin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC08614	violaxanthin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC09244	tabersonine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11130	3-hydroxyindolin-2-one	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11355	4-amino-4-deoxychorismate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11383	(S)-carvone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11409	(4S,6R)-trans-carveol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11412	(1R,4S)-isodihydrocarvone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11434	2-C-methyl-D-erythritol 4-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11435	4-CDP-2-C-methyl-D-erythritol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11436	4-CDP-2-C-methyl-D-erythritol 2-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11437	1-deoxy-D-xylulose 5-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11453	2-C-methyl-D-erythritol 2,4-cyclic diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11455	4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11457	3-(3-hydroxyphenyl)propanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11472	D-glycero-beta-D-manno-heptose 1,7-diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11482	holo-Lys2	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11516	2-(alpha-D-mannosyl)-3-phosphoglyceric acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11536	(2R)-O-phospho-3-sulfolactic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11537	(R)-3-sulfolactate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11538	cobalt-precorrin-2	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11539	cobalt-precorrin 3	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11540	cobalt-precorrin 4	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11542	cobalt-precorrin-6A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11543	cobalt-precorrin-6B	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11544	2-(alpha-D-mannosyl)-D-glycerate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11545	cobalt-precorrin 8	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11588	cis-3-(2-carboxyethyl)-3,5-cyclohexadiene-1,2-diol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11638	3-amino-2-oxopropyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11643	16-hydroxytabersonine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11675	16-methoxytabersonine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11700	10-deacetylbaccatin III	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11811	(2E)-4-hydroxy-3-methylbutenyl diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11821	5-hydroxyisouric acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11894	taxa-4,11-diene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11895	taxa-4(20),11-dien-5alpha-ol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11896	taxa-4(20),11-dien-5alpha-yl acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11898	10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11899	10-deacetyl-2-debenzoylbaccatin III	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11900	baccatin III	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11903	methanophenazine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11904	dihydromethanophenazine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC11937	(1S,4R)-1-hydroxylimonen-2-one	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12248	5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC12312	indolin-2-one	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC13482	phosphodimethylethanolamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC14180	S-(hydroxymethyl)glutathione	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC14463	(R)-3-hydroxy-3-methyl-2-oxopentanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC14610	(S)-5-oxo-2,5-dihydro-2-furylacetic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC14818	Fe2+	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC14899	3-dehydro-L-gulonate 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15522	4a-hydroxytetrahydrobiopterin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15547	1,4-dihydroxy-2-naphthoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15556	2-hydroxy-3-oxobutyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15602	Quinone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15603	Hydroquinone	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15606	1,2-dihydroxy-5-(methylthio)pent-1-en-3-one	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15607	3-oxo-3-ureidopropanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15650	5-(methylthio)-2,3-dioxopentyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15651	2-hydroxy-5-(methylsulfanyl)-3-oxopent-1-enyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15667	5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15670	heme A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15672	heme O	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15699	gamma-L-glutamylputrescine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15700	gamma-glutamyl-4-aminobutanal	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15767	4-(L-gamma-glutamylamino)butanoic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15769	2-hydroxy-1,4-benzoxazin-3-one	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15770	2,4-dihydroxy-1,4-benzoxazin-3-one	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15777	episterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15778	5,7,24(28)-ergostatrienol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15808	4alpha-methylzymosterol-4-carboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15816	3-dehydro-4-methylzymosterol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15925	GDP-L-gulose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15926	beta-L-galactose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15972	Enzyme N6-(lipoyl)lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15973	Enzyme N6-(dihydrolipoyl)lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15986	2,6-dihydroxypseudooxynicotine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC15987	4-(methylamino)butanoate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16142	germacrene D	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16143	germacradienol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16144	dehydrosqualene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16145	4,4'-diaponeurosporene	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16146	4,4'-diaponeurosporenic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16147	glycosyl-4,4'-diaponeurosporenic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16148	staphyloxanthin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16150	nicotine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16153	UDP-4-amino-4-deoxy-L-arabinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16154	UDP-4-deoxy-4-formamido-beta-L-arabinose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16155	UDP-beta-L-threo-pentopyranos-4-ulose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16156	4-deoxy-4-formamido-alphaL-arabinose undecaprenyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16157	4-amino-4-deoxy-alpha-L-arabinose undecaprenyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16159	2-formylglutarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16186	L-ascorbate 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16236	protein N(6)-(octanoyl)lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16237	protein N(6)-(lipoyl)lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16238	lipoyl-AMP	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16240	apoprotein	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16242	cobalt-precorrin 5A	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16243	cobalt-precorrin 5B	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16390	2-hydroxymethylglutarate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16488	fructoselysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16489	fructoselysine 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16519	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16523	N-(3'R)-debenzoyl-2'-deoxytaxol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16524	N-(3'R)-debenzoyltaxol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16636	tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16638	O-phosphoseryl-tRNA(Sec)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16639	beta-D-ribofuranose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16737	5-deoxy-D-glucuronic acid	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC16833	beta-phenylalanoyl-CoA	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC17023	sulfur donor	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC17209	2-deoxy-scyllo-inosose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC17401	cobalt-factor III	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC17556	di-trans,poly-cis-undecaprenyl phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC17580	2-deoxy-scyllo-inosamine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC17581	3-amino-2,3-dideoxy-scyllo-inosose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC18050	beta-D-fructofuranosyl alpha-D-mannopyranoside 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC18068	beta-D-fructofuranosyl alpha-D-mannopyranoside	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19671	amicyanin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19672	reduced amicyanin	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19847	demethylmenaquinol	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19878	D-glycero-alpha-D-manno-heptose 7-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19879	D-glycero-alpha-D-manno-heptose 1,7-diphosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19880	D-glycero-alpha-D-manno-heptose 1-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19881	GDP-D-glycero-alpha-D-manno-heptose	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19885	[LysW]	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19886	[LysW]-L-2-aminoadipate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19887	[LysW]-L-2-aminoadipyl 6-phosphate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19888	[LysW]-L-2-aminoadipate 6-semialdehyde	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC19889	[LysW]-L-lysine	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPC20258	(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPX00024	pectate(n-2)	http://purl.obolibrary.org/obo/UPa_UPC00000	compound		
http://purl.obolibrary.org/obo/UPa_UPA00001	biological process				A process occurring in living organisms.
http://purl.obolibrary.org/obo/UPa_UPC00000	compound				A chemical compound involved in a UniPathway pathway.
http://purl.obolibrary.org/obo/BFO_0000002	continuant				An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts.
http://purl.obolibrary.org/obo/BFO_0000003	occurrent				An entity that has temporal parts and that happens, unfolds or develops through time.
http://purl.obolibrary.org/obo/UPa_UCR00000	reaction				A chemical reaction involved in a UniPathway pathway.
http://purl.obolibrary.org/obo/UPa_UER00000	enzymatic-reaction				An enzymatic-reaction involved in a UniPathway pathway. An enzymatic-reaction is a set of alternate sequence-reactions, catalyzed by the same enzyme. It aims at representing ambiguity on co-substrate/co-product (e.g NAD(P)H.
http://purl.obolibrary.org/obo/UPa_ULS00000	linear sub-pathway				A linear sub-pathway involved in a UniPathway pathway. A linear sub-pathway is a path of enzymatic reactions.
http://purl.obolibrary.org/obo/RO_0002234	has output	http://purl.obolibrary.org/obo/RO_0000057	has participant	produces	p has output c iff c is a participant in p, c is present at the end of p, and c is not present at the beginning of p.
http://purl.obolibrary.org/obo/RO_0002218	has active participant	http://purl.obolibrary.org/obo/RO_0000057	has participant	has agent	x has participant y if and only if x realizes some active role that inheres in y
http://purl.obolibrary.org/obo/BFO_0000051	has part	http://purl.obolibrary.org/obo/RO_0002131	overlaps	has_part	a core relation that holds between a whole and its part
http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	http://purl.obolibrary.org/obo/RO_0002434	interacts with	molecularly binds with	An interaction relationship in which the two partners are molecular entities that directly physically interact with each other for example via a stable binding interaction or a brief interaction during which one modifies the other.
http://purl.obolibrary.org/obo/RO_0002449	activity directly negatively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	activity directly regulates activity of	inhibits	Holds between molecular entities A and B where A can physically interact with B and in doing so negatively regulates a process that B is capable of.  For example, A and B may be gene products and binding of B by A negatively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/BFO_0000062	preceded by	http://purl.obolibrary.org/obo/RO_0002086	ends after	preceded_by	x is preceded by y if and only if the time point at which y ends is before or equivalent to the time point at which x starts. Formally: x preceded by y iff ω(y) <= α(x), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/BFO_0000050	part of	http://purl.obolibrary.org/obo/RO_0002131	overlaps	part_of	a core relation that holds between a part and its whole
http://purl.obolibrary.org/obo/RO_0002233	has input	http://purl.obolibrary.org/obo/RO_0000057	has participant	consumes	p has input c iff: p is a process, c is a material entity, c is a participant in p, c is present at the start of p, and the state of c is modified during p.
http://purl.obolibrary.org/obo/RO_0002215	capable of	http://purl.obolibrary.org/obo/RO_0002216	capable of part of	has function realized in	A relation between a material entity (such as a cell) and a process, in which the material entity has the ability to carry out the process. 
http://purl.obolibrary.org/obo/RO_0002217	actively participates in	http://purl.obolibrary.org/obo/RO_0000056	participates in	agent in	x actively participates in y if and only if x participates in y and x realizes some active role
http://purl.obolibrary.org/obo/RO_0002331	involved in	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	enables part of	c involved_in p if and only if c enables some process p', and p' is part of p
http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	involved in or reguates	c involved in or regulates p if and only if either (i) c is involved in p or (ii) c is involved in regulation of p
http://purl.obolibrary.org/obo/RO_0002216	capable of part of	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	has function in	c stands in this relationship to p if and only if there exists some p' such that c is capable_of p', and p' is part_of p.
http://purl.obolibrary.org/obo/RO_0002329	part of structure that is capable of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to	0	this relation holds between c and p when c is part of some c', and c' is capable of p.
http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	influences (processual)	p 'causally upstream or within' q iff (1) the end of p is before the end of q and (2) the execution of p exerts some causal influence over the outputs of q; i.e. if p was abolished or the outputs of p were to be modified, this would necessarily affect q.
http://purl.obolibrary.org/obo/RO_0002432	is active in	http://purl.obolibrary.org/obo/RO_0002328	functionally related to	executes activity in	c executes activity in d if and only if c enables p and p occurs_in d.  Assuming no action at a distance by gene products, if a gene product enables (is capable of) a process that occurs in some structure, it must have at least some part in that structure.
http://purl.obolibrary.org/obo/RO_0002450	activity directly positively regulates activity of	http://purl.obolibrary.org/obo/RO_0002448	activity directly regulates activity of	activates	Holds between molecular entities A and B where A can physically interact with B and in doing so positively regulates a process that B is capable of.  For example, A and B may be gene products and binding of B by A positively regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0002025	has effector activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has effector activity' B if A and B are GO molecular functions (GO_0003674),  A 'has component activity' B and B is the effector (output function) of B.  Each compound function has only one effector activity.
http://purl.obolibrary.org/obo/BFO_0000063	precedes	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		x precedes y if and only if the time point at which x ends is before or equivalent to the time point at which y starts. Formally: x precedes y iff ω(x) <= α(y), where α is a function that maps a process to a start point, and ω is a function that maps a process to an end point.
http://purl.obolibrary.org/obo/RO_0002018	has component process	http://purl.obolibrary.org/obo/RO_0002180	has component		w 'has process component' p if p and w are processes,  w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0002333	enabled by	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of enables
http://purl.obolibrary.org/obo/RO_0002404	causally downstream of	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of upstream of
http://purl.obolibrary.org/obo/RO_0002412	immediately causally upstream of	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		p is immediately causally upstream of q iff both (a) p immediately precedes q and (b) p is causally upstream of q. In addition, the output of p  must be an input of q.
http://purl.obolibrary.org/obo/RO_0002448	activity directly regulates activity of	http://purl.obolibrary.org/obo/RO_0002566	causally influences		Holds between molecular entities A and B where A can physically interact with B and in doing so regulates a process that B is capable of.  For example, A and B may be gene products and binding of B by A regulates the kinase activity of B.
http://purl.obolibrary.org/obo/RO_0002566	causally influences	http://purl.obolibrary.org/obo/RO_0002506	causal relation between material entities		Holds between materal entities a and b if the activity of a is causally upstream of the activity of b, or causally upstream of a an activity that modifies b
http://purl.obolibrary.org/obo/RO_0002263	acts upstream of	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		c acts upstream of p if and only if c enables some f that is involved in p' and p' occurs chronologically before p, is not part of p, and affects the execution of p. c is a material entity and f, p, p' are processes.
http://purl.obolibrary.org/obo/RO_0002131	overlaps	http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to		x overlaps y if and only if there exists some z such that x has part z and z part of y
http://purl.obolibrary.org/obo/RO_0002411	causally upstream of	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		p is causally upstream of q if and only if p precedes q and p and q are linked in a causal chain
http://purl.obolibrary.org/obo/RO_0002211	regulates	http://purl.obolibrary.org/obo/RO_0002411	causally upstream of		process(P1) regulates process(P2) iff: P1 results in the initiation or termination of P2 OR affects the frequency of its initiation or termination OR affects the magnitude or rate of output of P2.
http://purl.obolibrary.org/obo/RO_0002212	negatively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		Process(P1) negatively regulates process(P2) iff: P1 terminates P2, or P1 descreases the the frequency of initiation of P2 or the magnitude or rate of output of P2.
http://purl.obolibrary.org/obo/RO_0002213	positively regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		Process(P1) postively regulates process(P2) iff: P1 initiates P2, or P1 increases the the frequency of initiation of P2 or the magnitude or rate of output of P2.
http://purl.obolibrary.org/obo/RO_0002180	has component	http://purl.obolibrary.org/obo/BFO_0000051	has part		w 'has component' p if w 'has part' p and w is such that it can be directly disassembled into into n parts p, p2, p3, ..., pn, where these parts are of similar type.
http://purl.obolibrary.org/obo/RO_0002352	input of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of has input
http://purl.obolibrary.org/obo/RO_0002353	output of	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		inverse of has output
http://purl.obolibrary.org/obo/RO_0002023	directly negatively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly negatively regulated by process(P1) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P2 directly negatively regulated by P1.
http://purl.obolibrary.org/obo/RO_0002024	directly positively regulated by	http://purl.obolibrary.org/obo/RO_0002022	directly regulated by		Process(P2) is directly postively regulated by process(P1) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P2 is directly postively regulated by P1.
http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		c acts upstream of or within p if c is enables f, and f is causally upstream of or within p. c is a material entity and p is an process.
http://purl.obolibrary.org/obo/RO_0002019	has ligand	http://purl.obolibrary.org/obo/RO_0002233	has input		A relationship that holds between between a receptor and an chemical entity, typically a small molecule or peptide, that carries information between cells or compartments of a cell and which binds the receptor and regulates its effector function.
http://purl.obolibrary.org/obo/RO_0004031	enables subfunction	http://purl.obolibrary.org/obo/RO_0002328	functionally related to		Holds between an entity and an process P where the entity enables some larger compound process, and that larger process has-part P.
http://purl.obolibrary.org/obo/RO_0004034	acts upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect		c 'acts upstream of, positive effect' p if c is enables f, and f is causally upstream of p, and the direction of f is positive
http://purl.obolibrary.org/obo/RO_0004035	acts upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect		c 'acts upstream of, negative effect' p if c is enables f, and f is causally upstream of p, and the direction of f is negative
http://purl.obolibrary.org/obo/RO_0002334	regulated by	http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within		inverse of regulates
http://purl.obolibrary.org/obo/RO_0002335	negatively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of negatively regulates
http://purl.obolibrary.org/obo/RO_0002336	positively regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		inverse of positively regulates
http://purl.obolibrary.org/obo/RO_0002427	causally downstream of or within	http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes		inverse of causally upstream of or within
http://purl.obolibrary.org/obo/RO_0002500	causal agent in process	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		A relationship between a material entity and a process where the material entity has some causal role that influences the process
http://purl.obolibrary.org/obo/RO_0002501	causal relation between processes	http://purl.obolibrary.org/obo/RO_0002410	causally related to		p is causally related to q if and only if p or any part of p and q or any part of q are linked by a chain of events where each event pair is one of direct activation or direct inhibition. p may be upstream, downstream, part of or a container of q.
http://purl.obolibrary.org/obo/RO_0002584	has part structure that is capable of	http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process		s 'has part structure that is capable of' p if and only if there exists some part x such that s 'has part' x and x 'capable of' p
http://purl.obolibrary.org/obo/RO_0002595	causal relation between material entity and a process	http://purl.obolibrary.org/obo/RO_0002410	causally related to		A relationship that holds between a material entity and a process in which causality is involved, with either the material entity or some part of the material entity exerting some influence over the process, or the process influencing some aspect of the material entity.
http://purl.obolibrary.org/obo/RO_0002596	capable of regulating	http://purl.obolibrary.org/obo/RO_0002500	causal agent in process		Holds between c and p if and only if c is capable of some activity a, and a regulates p.
http://purl.obolibrary.org/obo/RO_0002597	capable of negatively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a negatively regulates p.
http://purl.obolibrary.org/obo/RO_0002598	capable of positively regulating	http://purl.obolibrary.org/obo/RO_0002596	capable of regulating		Holds between c and p if and only if c is capable of some activity a, and a positively regulates p.
http://purl.obolibrary.org/obo/RO_0002608	process has causal agent	http://purl.obolibrary.org/obo/RO_0002410	causally related to		Inverse of 'causal agent in process'
http://purl.obolibrary.org/obo/RO_0002015	has positive regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that positively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is positively regulated by B.
http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity	http://purl.obolibrary.org/obo/RO_0002017	has component activity		A 'has regulatory component activity' B if A and B are GO molecular functions (GO_0003674), A has_component B and A is regulated by B.
http://purl.obolibrary.org/obo/RO_0002014	has negative regulatory component activity	http://purl.obolibrary.org/obo/RO_0002013	has regulatory component activity		A relationship that holds between a GO molecular function and a component of that molecular function that negatively regulates the activity of the whole.  More formally, A 'has regulatory component activity' B iff :A and B are GO molecular functions (GO_0003674), A has_component B and A is negatively regulated by B.
http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of	http://purl.obolibrary.org/obo/RO_0002431	involved in or involved in regulation of		c involved in regulation of p if c is involved in some p' and p' regulates some p
http://purl.obolibrary.org/obo/RO_0002429	involved in positive regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' positively regulates some p
http://purl.obolibrary.org/obo/RO_0002430	involved in negative regulation of	http://purl.obolibrary.org/obo/RO_0002428	involved in regulation of		c involved in regulation of p if c is involved in some p' and p' negatively regulates some p
http://purl.obolibrary.org/obo/RO_0002578	directly regulates	http://purl.obolibrary.org/obo/RO_0002211	regulates		Process(P1) directly regulates process(P2) iff: P1 regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  regulates the kinase activity (P2) of protein B then P1 directly regulates P2.
http://purl.obolibrary.org/obo/RO_0002629	directly positively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		Process(P1) directly postively regulates process(P2) iff: P1 positively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding positively regulates the kinase activity (P2) of protein B then P1 directly positively regulates P2.
http://purl.obolibrary.org/obo/RO_0002630	directly negatively regulates	http://purl.obolibrary.org/obo/RO_0002578	directly regulates		Process(P1) directly negatively regulates process(P2) iff: P1 negatively regulates P2 via direct physical interaction between an agent executing P1 (or some part of P1) and an agent executing P2 (or some part of P2).  For example, if protein A has protein binding activity(P1) that targets protein B and this binding  negatively regulates the kinase activity (P2) of protein B then P1 directly negatively regulates P2.
http://purl.obolibrary.org/obo/RO_0002087	immediately preceded by	http://purl.obolibrary.org/obo/BFO_0000062	preceded by	starts_at_end_of	
http://purl.obolibrary.org/obo/RO_0002090	immediately precedes	http://purl.obolibrary.org/obo/BFO_0000063	precedes	meets	
http://purl.obolibrary.org/obo/RO_0002327	enables	http://purl.obolibrary.org/obo/RO_0002215	capable of	is executing	
http://purl.obolibrary.org/obo/RO_0002447	phosphorylates	http://purl.obolibrary.org/obo/RO_0002436	molecularly interacts with	An interaction relation between x and y in which x catalyzes a reaction in which a phosphate group is added to y.	
http://purl.obolibrary.org/obo/RO_0002405	immediately causally downstream of	http://purl.obolibrary.org/obo/RO_0002404	causally downstream of		
http://purl.obolibrary.org/obo/RO_0002017	has component activity	http://purl.obolibrary.org/obo/RO_0002018	has component process		
http://purl.obolibrary.org/obo/RO_0002559	causally influenced by	http://purl.obolibrary.org/obo/RO_0002506	causal relation between material entities		
http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)		
http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property	http://purl.obolibrary.org/obo/RO_0002563	interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002481	is kinase activity	http://purl.obolibrary.org/obo/RO_0002564	molecular interaction relation helper property		
http://purl.obolibrary.org/obo/RO_0002086	ends after	http://purl.obolibrary.org/obo/RO_0002222	temporally related to		
http://purl.obolibrary.org/obo/RO_0002304	causally upstream of, positive effect	http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect		
http://purl.obolibrary.org/obo/RO_0002305	causally upstream of, negative effect	http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect		
http://purl.obolibrary.org/obo/RO_0004033	acts upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0004032	acts upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002264	acts upstream of or within		
http://purl.obolibrary.org/obo/RO_0002022	directly regulated by	http://purl.obolibrary.org/obo/RO_0002334	regulated by		
http://purl.obolibrary.org/obo/RO_0002506	causal relation between material entities	http://purl.obolibrary.org/obo/RO_0002410	causally related to		
http://purl.obolibrary.org/obo/RO_0004046	causally upstream of or within, negative effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://purl.obolibrary.org/obo/RO_0004047	causally upstream of or within, positive effect	http://purl.obolibrary.org/obo/RO_0002418	causally upstream of or within		
http://purl.obolibrary.org/obo/RO_0000056	participates in			participates_in	a relation between a continuant and a process, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/RO_0000057	has participant			has_participant	a relation between a process and a continuant, in which the continuant is somehow involved in the process
http://purl.obolibrary.org/obo/BFO_0000066	occurs in			unfolds_in	b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
http://purl.obolibrary.org/obo/BFO_0000067	contains process				[copied from inverse property 'occurs in'] b occurs_in c =def b is a process and c is a material entity or immaterial entity& there exists a spatiotemporal region r and b occupies_spatiotemporal_region r.& forall(t) if b exists_at t then c exists_at t & there exist spatial regions s and s’ where & b spatially_projects_onto s at t& c is occupies_spatial_region s’ at t& s is a proper_continuant_part_of s’ at t
http://purl.obolibrary.org/obo/RO_0003000	produces				a produces b if some process that occurs_in a has_output b, where a and b are material entities. Examples: hybridoma cell line produces monoclonal antibody reagent; chondroblast produces avascular GAG-rich matrix.
http://purl.obolibrary.org/obo/RO_0003001	produced by				a produced_by b iff some process that occurs_in b has_output a.
http://purl.obolibrary.org/obo/RO_0002434	interacts with				A relationship that holds between two entities in which the processes executed by the two entities are causally connected.
http://purl.obolibrary.org/obo/RO_0002323	mereotopologically related to				A mereological relationship or a topological relationship
http://purl.obolibrary.org/obo/RO_0002328	functionally related to				A grouping relationship for any relationship directly involving a function, or that holds because of a function of one of the related entities.
http://purl.obolibrary.org/obo/RO_0002410	causally related to				This relation groups causal relations between material entities and causal relations between processes
http://purl.obolibrary.org/obo/RO_0002479	has part that occurs in				p has part that occurs in c if and only if there exists some p1, such that p has_part p1, and p1 occurs in c.
http://purl.obolibrary.org/obo/RO_0002464	helper property (not for use in curation)				
http://purl.obolibrary.org/obo/RO_0002222	temporally related to				
http://purl.obolibrary.org/obo/upa#has_connecting_compound	has connecting compound