organosulfur compound valdecoxib C16H14N2O3S LNPDTQAFDNKSHK-UHFFFAOYSA-N InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20) HMDB:HMDB0005033 PMID:20717044 DrugBank:DB00580 LINCS:LSM-5305 Wikipedia:Valdecoxib Cc1onc(-c2ccccc2)c1-c1ccc(cc1)S(N)(=O)=O Drug_Central:2799 chebi_ontology 4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide p-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide Bextra 314.35900 A member of the class of isoxazoles that is isoxazole which is substituted at positions 3, 4 and 5 by phenyl, p-sulfamoylphenyl and methyl groups, respectively. A selective cyclooxygenase 2-inhibitor, it used as a nonsteroidal anti-inflammatory drug (NSAID) for the treatment of arthritis from 2001 until 2005, when it was withdrawn following concerns of an associated increased risk of heart attack and stroke. 0 PDBeChem:COX CHEBI:41662 4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide PMID:21073910 Reaxys:8563786 314.07251 valdecoxib CAS:181695-72-7 KEGG:D02709 PMID:21769548 CHEBI:63634 valdecoxibum PMID:20467258 PMID:21720517