memantine Reaxys:2075983 PMID:22425751 PMID:22030128 PMID:21955815 Drug_Central:1679 PMID:21953515 3,5-dimethyladamantan-1-amine CHEBI:64312 KEGG:D08174 memantina 1-Amino-3,5-dimethyladamantane memantine PMID:22248638 PMID:20104942 BUGYDGFZZOZRHP-UHFFFAOYSA-N 3,5-Dimethyl-1-aminoadamantane chebi_ontology PMID:22327556 PMID:22134197 1,3-Dimethyl-5-adamantanamine 179.30180 Patent:US2011282100 179.16740 PMID:22311362 CAS:19982-08-2 PMID:22300835 memantinum CHEBI:34832 InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3 C12H21N 3,5-Dimethyl-1-adamantanamine 3,5-Dimethyltricyclo(3.3.1.1(3,7))decan-1-amine PMID:22414570 DrugBank:DB01043 PMID:22392787 PMID:22245025 KEGG:C13736 PMID:22290557 Wikipedia:Memantine PMID:22329473 CC12CC3CC(C)(C1)CC(N)(C3)C2 0 A primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. LINCS:LSM-5154 PMID:22297273 molecular pathway modifying agent therapy