organohalogen compound organonitrogen compound lumiracoxib An amino acid that is phenylacetic acid which is substituted at position 2 by the nitrogen of 2-chloro-6-fluoroaniline and at position 5 by a methyl group. A highly selective cyclooxygenase 2 inhibitor, it was briefly used for the treatment of osteoarthritis, but was withdrawn due to concersns of hepatotoxicity. Drug_Central:1618 PMID:15311562 COX189 PMID:21688392 {2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl}acetic acid CHEBI:73044 Prexige KHPKQFYUPIUARC-UHFFFAOYSA-N PDBeChem:LUR Wikipedia:Lumiracoxib Reaxys:9784107 HMDB:HMDB0015403 COX 189 C15H13ClFNO2 Cc1ccc(Nc2c(F)cccc2Cl)c(CC(O)=O)c1 PMID:22142375 0 PMID:15456339 KEGG:D03714 DrugBank:DB01283 chebi_ontology 2-((2-chloro-6-fluorophenyl)amino)-5-methylbenzeneacetic acid InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20) PMID:22732767 PMID:22621454 PMID:22069133 PMID:19800190 PMID:14965322 lumiracoxib COX-189 lumiracoxibum PMID:17380211 293.06188 CAS:220991-20-8 293.72100