cholinesterase inhibitor therapy 2019-01-22T18:32:56Z EC 3.1.1.8 (cholinesterase) inhibitor therapy cholinesterase inhibitor medication therapy CHEBI:37733 treatment with EC 3.1.1.8 (cholinesterase) inhibitor They are a group of drugs that block the normal breakdown of acetylcholine (ACh) into acetate and choline and thereby increase both the levels and duration of actions of acetylcholine found in the central and peripheral nervous system. cholinesterase inhibitor drug treatment Neurogenerative diseases such as Alzheimer disease, Parkinson disease, and Lewy body dementia are indications for cholinesterase inhibitor therapy. enzyme inhibitor agent therapy