cardiovascular agent therapy ACE inhibitor therapy 2020-06-04T17:31:19Z CHEBI:147289 Treatment with angiotensin-converting enzyme inhibitor Use of a drug that inhibits angiotensin-converting enzyme (ACE), an enzyme that catalyzes the conversion of angiotensin I to angiotensin II. Inhibition of ACE results in a reduction in angiotensin II and angiotensin II-induced aldosterone secretion, causing vasodilation and natriuresis. NCIT:C247 Treatment with ACE inhibitor angiotensin-converting enzyme inhibitor therapy