<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/ADO?iri=http://purl.obolibrary.org/obo/NCIT_C2020"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns2="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P366"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000412"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P106"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_NHC0"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P368"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P108"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/NCIT_P207"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_23924 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23924">
        <rdfs:label>enzyme inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCIT_C2020 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCIT_C2020">
        <rdfs:label>Farnesyl Transferase Inhibitor</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_23924"/>
        <oboInOwl:hasExactSynonym>Protein Farnesyltransferase Inhibitor</oboInOwl:hasExactSynonym>
        <ns2:NCIT_P366>Farnesyl_Transferase_Inhibitor</ns2:NCIT_P366>
        <ns2:NCIT_P106>Chemical Viewed Functionally</ns2:NCIT_P106>
        <oboInOwl:hasExactSynonym>Farnesyl Transferase Inhibitor</oboInOwl:hasExactSynonym>
        <ns2:NCIT_NHC0>C2020</ns2:NCIT_NHC0>
        <oboInOwl:hasExactSynonym>Farnesyltransferase Inhibitors</oboInOwl:hasExactSynonym>
        <ns2:IAO_0000115>Any substance that inhibits protein farnesyltransferase, an enzyme that catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine. Protein farnesyltransferase is involved in Ras-mediated post-translational modification. Inhibition of protein farnesyltransferase may inhibit the oncogenic activity of Ras.</ns2:IAO_0000115>
        <oboInOwl:hasExactSynonym>Farnesyl Transferase Inhibitors</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>FTI</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Protein Farnesyltransferase Inhibitors</oboInOwl:hasExactSynonym>
        <ns2:NCIT_P368>CHEBI:64133</ns2:NCIT_P368>
        <ns2:NCIT_P108>Farnesyl Transferase Inhibitor</ns2:NCIT_P108>
        <ns2:NCIT_P207>C1517132</ns2:NCIT_P207>
        <ns2:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/ncit.owl"/>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



