]> sertraline LINCS:LSM-3843 Patent:US4536518 PMID:21823671 HMDB:HMDB0005010 PMID:19502000 Reaxys:5753709 DrugBank:DB01104 PDBeChem:SRE KEGG:C07246 KEGG:D02360 Beilstein:5753709 CAS:79617-96-2 Wikipedia:Sertraline Drug_Central:2436 (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine Sertraline chebi_ontology sertralina sertralinum sertraline (1S,4S)-sertraline cis-(+)-sertraline (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine (+)-sertraline CP 51974 CHEBI:9123 A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. 0 C17H17Cl2N InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1 VGKDLMBJGBXTGI-SJCJKPOMSA-N 306.23000 305.07380 [H][C@]1(CC[C@H](NC)c2ccccc12)c1ccc(Cl)c(Cl)c1 organohalogen compound organic molecule organonitrogen compound