rapid progression RapidProgr The term rapid progression is a conventional clinical term. An exact timeframe sould not be offered since it would have to refer to a wide range of signs and symptoms without a scientific evidence base. Using an arbitrarily restrictive setpoint might bias future data collection unnecessarily. Anaphylaxis: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine 25 (2007) 5675–5684 respiratory distress diagnosis Brighton diagnosis result clinical diagnosis of uncompensated shock dermatologic or mucosal sign generalized urticaria or generalized erythema finding angioedema finding generalized pruritus with skin rash finding measured hypotension finding uncompensated shock sign finding tachycardia finding capillary refill time > 3s finding reduced central pulse volume finding stridor finding upper airway swelling finding tachypnoea finding increased use of accessory respiratory muscles finding recession finding cyanosis finding grunting finding respiratory distress sign finding red and itchy eyes finding reduced peripheral circulation finding reduced peripheral circulation diagnosis hoarse voice finding sensation of throat closure finding sneezing or rhinorrhea finding diarrhoea finding abdominal pain finding nausea finding vomiting finding mast cell tryptase elevation > upper normal limit finding cardiovascular sign respiratory sign gastrointestinal sign dry cough finding chest tightness finding indrawing finding rhinorrhea finding sore throat finding wheezing finding erythema finding red eyes finding itchy eyes finding prickle sensation finding pruritus finding rash finding urticaria finding decreased level of consciousness finding sneezing finding difficulty breathing finding diagnosis textual entity clinical finding