capable of capable of neurecto-epithelial cell interstitial cell of Cajal 2010-07-22T03:26:00Z intestinal pacemaker cell BTO:0003914 ICC FMA:86573 This is a cell found in the gastrointestinal tract of mammals and serves as a pacemaker that triggers gut contraction. ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumors (GISTs) arise. regulation of hindgut contraction