negatively regulates negative regulation of macromolecule biosynthetic process negative regulation of DNA metabolic process biological regulation DNA biosynthetic process regulation of DNA biosynthetic process negative regulation of DNA biosynthetic process negative regulation of DNA biosynthesis negative regulation of DNA synthesis biological_process 2010-12-08T04:48:20Z negative regulation of DNA anabolism Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process. GO:2000279 negative regulation of DNA formation