confers_resistance_to_antibiotic confers_resistance_to_drug_class tigecycline glycylcycline confers_resistance_to_antibiotic confers_resistance_to_drug_class mepA MepA is an efflux protein regulated by MepR and part of the MepRAB cluster. Its presence in Staphylococcus aureus led to multidrug resistance, while it has also been shown to decrease tigecycline susceptibility. antibiotic_resistance ARO:3000026 mepA multidrug and toxic compound extrusion (MATE) transporter