confers_resistance_to_antibiotic confers_resistance_to_drug_class participates_in streptogramin antibiotic confers_resistance_to_antibiotic confers_resistance_to_drug_class acylation of antibiotic conferring resistance streptogramin inactivation enzyme streptogramin vat acetyltransferase ARO:3000453 Streptogramin A acetyltransferase (SAT) vat (Virginiamycin acetyltransferases) enzymes catalyze the transfer of an acetyl group from acetyl-CoA to the secondary alcohol of streptogramin A compounds, thus inactivating virginiamycin-like antibiotics and conferring resistance to these compounds. antibiotic_resistance virginiamycin M1 madumycin II griseoviridin dalfopristin