confers_resistance_to_antibiotic erythromycin roxithromycin lincomycin telithromycin clarithromycin clindamycin confers_resistance_to_antibiotic tylosin spiramycin azithromycin dirithromycin Erm 23S ribosomal RNA methyltransferase pristinamycin IA quinupristin ErmR ARO:3000594 ErmR antibiotic_resistance ErmR is a methyltransferase found in the erythromycin producer Aeromicrobium erythreum. Like other Erm enzymes, it catalyzes the methylation of A2058 of the 23S ribosomal RNA. The gene is found within the erythromycin biosynthetic cluster and is responsible for self-resistance. virginiamycin M1 madumycin II griseoviridin dalfopristin pristinamycin IB virginiamycin S2 pristinamycin IC vernamycin C patricin A patricin B ostreogrycin B3 oleandomycin