targeted_by_antibiotic targeted_by_antibiotic mupirocin protein synthesis machinery targeted by antibiotic antibiotic sensitive Isoleucyl-tRNA transferase antibiotic_resistance Isoleucyl-tRNA transferase recognizes isoleucine codons and works with the ribosome to incorporate isoleucine amino acids into polypeptide chains. It can be targeted by antibiotics that have an analog of isoleucine through competitive inhibition. ileS ARO:3000732