targeted_by targeted_by_antibiotic part_of astromicin neomycin dibekacin streptothricin amikacin gentamicin C aminoglycoside antibiotic ribostamycin butirosin tigecycline sisomicin apramycin netilmicin spectinomycin streptomycin kanamycin A tetracycline tobramycin doxycycline targeted_by targeted_by_antibiotic tetracycline antibiotic edeine minocycline hygromycin B chlortetracycline isepamicin G418 arbekacin gentamicin B paromomycin lividomycin demeclocycline oxytetracycline lividomycin A lividomycin B 30S ribosomal subunit ribonucleic acid antibiotic sensitive 16S rRNA antibiotic_resistance The 16S rRNA of the 30S ribosomal subunit helps to stabilize the aminoacyl-tRNAs for pairing with the mRNA codons. Some antibiotics (aminoglycosides) that target the 16S rRNA lead to mRNA misreading as well as premature termination. Other antibiotics (tetracyclines) that target the 16S rRNA prevent incoming charged-tRNAs from binding to the ribosome's A-site, stopping elongation. ARO:3000755