GE2270A ChEBI:29584 ChEMBL:CHEMBL1766417 antibiotic_resistance ARO:3001237 PubChem:16129640 GE2270A is the model molecule of cyclic thiazolyl peptide elfamycins. GE2270A is produced by Planobispora rosea. Biosynthesis of the molecule has been shown to originate as a ribosomally synthesized peptide that undergoes significant post-translational modification. Clinical use of cyclic thiazolyl peptides is hindered by their low water solubility and bioavailability. cyclic thiazolyl peptide elfamycin