confers_resistance_to_antibiotic lincomycin confers_resistance_to_antibiotic Erm 23S ribosomal RNA methyltransferase ErmU ARO:3001305 lrmB antibiotic_resistance ErmU is a methyltransferase found in the lincomycin producer Streptomyces lincolnensis. Like other Erm enzymes, it catalyzes the methylation of A2058 of the 23S ribosomal RNA. Specifically, this enzyme transfers only one methyl group. The gene is found in the lincomycin biosynthetic cluster and is responsible for self-resistance. ErmU