confers_resistance_to_antibiotic confers_resistance_to_drug_class derives_from confers_resistance_to_antibiotic confers_resistance_to_drug_class ethambutol polyamine antibiotic antibiotic sensitive aftA ethambutol resistant aftA Arabinofuranosyltransferases allow for the polymerization of arabinose to form arabinan. Arabinan is required for formation of mycobacterial cell walls and arabinosyltransferases are targets of the drug ethambutol. Mutations in these genes can confer resistance to ethambutol. antibiotic_resistance ARO:3002876 antibiotic resistant aftA