confers_resistance_to_antibiotic confers_resistance_to_antibiotic isoniazid Mycobacterium tuberculosis inhA mutations conferring resistance to isoniazid Mtub_inhA_INH ARO:3003393 inhA is a enoyl-acyl carrier reductase used in lipid metabolism and farry acid biosynthesis. It is inhibited by isoniazid. mutations in the promoter region or multiple copies of the inhA shows marked resistance to isoniazid mediated inhibition of mycolic acid biosynthesis. Rv1484 antibiotic_resistance isoniazid resistant inhA