confers_resistance_to_antibiotic confers_resistance_to_antibiotic fusidic acid antibiotic resistant fusE Staphylococcus aureus fusE with mutation conferring resistance to fusidic acid antibiotic_resistance Saur_fusE_FA ARO:3003737 rplF 50S ribosomal subunit protein L6 The mutations to the rplF gene encoding riboprotein L6 have been shown to cause fusidic acid resistance, demonstrating a potential secondary site of action of the antibiotic that is blocked through these mutations. Several types of mutations have been identified that cause resistance, including SNPs, frameshift mutations and early stop codons.