confers_resistance_to_drug_class antibiotic resistant gene variant or mutant confers_resistance_to_drug_class Antibiotic resistant nfsB The nsfB gene encodes a minor oxygen-insensitive nitroreductase. NfsB reduces a broad range of nitroaromatic compounds including the antibiotics nitrofurazone and nitrofurantoin. NfsB is a flavin mononucleotide (FMN)-containing protein and uses both NADH and NADPH as a source of reducing equivalents. Mutations in nfsB lead to increased resistance to nitrofurazone and furazolidone in an nfsA mutant background. antibiotic_resistance ARO:3003755 nitrofuran antibiotic