part_of protein of two-component regulatory system modulating antibiotic efflux kdpE ARO:3003841 kdpE antibiotic_resistance kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding. kdpDE