confers_resistance_to_antibiotic ciprofloxacin confers_resistance_to_antibiotic fluoroquinolone resistant gyrA Haemophilus parainfluenzae gyrA conferring resistance to fluoroquinolones Hpin_gyrA_FLO Point mutation of Haemophilus parainfluenzae gyrA resulted in the lowered affinity between fluoroquinolones and GyrA. Thus, conferring resistance. Both Ser and Tyr are hydrophilic amino acids, however Tyr has an additional bulky hydrophobic group which could affect the interaction between the DNA gyrase with quinolones. antibiotic_resistance ARO:3003924