prothionamide protionamide PubChem:666418 ARO:3004025 Prothionamide is a thioamide derivative with antibacterial properties. It increases cell wall permeability and decreases cell wall damage resistance by inhibition of mycolic acid synthesis, resulting in cell death. It is particularly used to treat M. tuberculosis and M. leprae infections. CAS:14222-60-7 ChEMBL:CHEMBL1378024 ChEBI:32066 antibiotic_resistance thioamide antibiotic