confers_resistance_to_drug_class derives_from antibiotic resistant gene variant or mutant confers_resistance_to_drug_class antibiotic sensitive fabI antibiotic resistant fabI antibiotic_resistance fabI is a enoyl-acyl carrier reductase used in lipid metabolism and fatty acid biosynthesis. The bacterial biocide Triclosan blocks the final reduction step in fatty acid elongation, inhibiting biosynthesis. Point mutations in fabI can confer resistance to Triclosan and Isoniazid. ARO:3004270 disinfecting agents and antiseptics isoniazid-like antibiotic