confers_resistance_to_antibiotic confers_resistance_to_drug_class fluoroquinolone antibiotic ciprofloxacin levofloxacin major facilitator superfamily (MFS) antibiotic efflux pump confers_resistance_to_antibiotic confers_resistance_to_drug_class ofloxacin QepA3 ARO:3004378 QepA3 antibiotic_resistance A plasmid-mediate quinolone efflux pump described in Klebsiella aerogenes and Escherichia coli. QepA3 confers resistance to fluoroquinolone antibiotics by expelling the antibiotic molecules from the cell. This is distinct from the usual chromosomal mutation mechanism of quinolone resistance. Described by Wang et al. 2017.