confers_resistance_to_antibiotic confers_resistance_to_antibiotic ethionamide inhA with mutations with conferring resistance to ethionamide Mycobacterium tuberculosis inhA mutations conferring resistance to ethionamide Mtub_inhA_ETO Rv1484 inhA is a enoyl-acyl carrier reductase used in lipid metabolism and farry acid biosynthesis. It is inhibited by ethionamide. Mutations in the promoter region or multiple copies of the inhA show marked resistance to ethionamide mediated inhibition of mycolic acid biosynthesis. ARO:3004876 antibiotic_resistance