fluoroquinolone antibiotic gemifloxacin Gemifloxacin is a broad-spectrum, fourth generation, oral fluoroquinolone antibiotic used in the treatment of various bacterial infections, primarily in the lungs. It has been discontinued for therapeutic use in the US over concerns of tendon and peripheral neuron toxicity, although it is still available for experimental application and elsewhere for therapeutic use. It is usually administered as a mesylate salt, gemifloxacin mesylate. antibiotic_resistance Factive ARO:3007165 ChEMBL:CHEMBL430 ChEBI:101853 PubChem:9571107 CAS:175463-14-6