macrocyclic peptide antibiotics zosurabalpin antibiotic_resistance ChEMBL:CHEMBL5314563 ARO:3007784 PubChem:148636827 Zosurabalpin is a macrocyclic peptide (MCP) antibiotic with potent antibacterial activity against Carbapenem-resistant Acinetobacter baumannii. The mechanism of action involves blocking the transport of bacterial lipopolysaccharide from the inner membrane to its destination on the outer membrane, through inhibition of the LptB2FGC complex.