nucleoside antibiotic 5-fluorocytosine ChEMBL:CHEMBL1463 ARO:3009160 ChEBI:5100 antibiotic_resistance CAS:2022-85-7 An antifungal compound that is converted into fluorouracil inside cells, thereby impairing the synthesis of proteins and DNA. This drug should almost always be used in combination with amphotericin B for systemic fungal infections, but the ratio is important since flucytosine can increase the toxicity of amphotericin B and vice versa. Flucytosine is typically indicated for Candida and Cryptococcus infections. PubChem:3366