<?xml version="1.0"?>
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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://purl.obolibrary.org/obo/ARO_3009165 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/ARO_3009165">
        <rdfs:label>antifungal without defined classification</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/ARO_3009173 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/ARO_3009173">
        <rdfs:label>butenafine</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/ARO_3009165"/>
        <oboInOwl:hasDbXref>ChEBI:3238</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ChEMBL:CHEMBL990</oboInOwl:hasDbXref>
        <oboInOwl:id>ARO:3009173</oboInOwl:id>
        <oboInOwl:hasOBONamespace>antibiotic_resistance</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>PubChem:2484</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CAS:101828-21-1</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>This is a Benzylamine Antifungal which is believed to inhibit the squalene epoxidase enzyme that is essential in the formation of sterols necessary for fungal cell membranes. It is typically used in the treatment of dermatological infections. Butenafine is trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is a tertiary amine and a member of naphthalenes.</ns3:IAO_0000115>
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