confers_resistance_to_antibiotic derives_from confers_resistance_to_antibiotic isavuconazole Candida albicans Erg11 with mutations conferring resistance to isavuconazole Mitochondrial electron transport chain (ETC) proteins involved in the respiratory chain complex for aerobic respiration in fungal organisms. Mutations in these proteins are associated with antifungal resistance by disrupting the inhibitory effect of certain drugs, such as Azoxystrobin. ARO:3009198 antibiotic_resistance antifungal susceptible ERG11 lanosterol-14-alpha-demethylase azole resistant fungal 14 alpha demethylase