confers_resistance_to_antibiotic derives_from confers_resistance_to_antibiotic fungal uracil phosphoribosyltransferase 5-fluorocytosine fungal pyrimidine metabolism pathway enzyme targeted by antibiotic Nakaseomyces glabratus Fur1 with mutations associated with resistance to 5-fluorocytosine ARO:3009286 Fur1 encodes a uracil phosphoribosyltransferase which is essential in nucleotide synthesis in eukaryotes inclusive of fungi. Mutations to the enzyme have been show to confer resistance to 5-fluorocystosine. antibiotic_resistance