confers_resistance_to_antibiotic confers_resistance_to_antibiotic cycloheximide Trychophyton rubrum MFS1 with mutations conferring resistance against cyclohexamide ARO:3009291 The MFS family of genes in fungi are part of the Major Facilitator Superfamily efflux pumps which are responsible for the export of antifungal compounds across the cell membrane. Mutations to this family of genes can result in anti-fungal resistance inclusive of a protein synthesis inhibiting compound like cyclohexamide. antibiotic_resistance fungal MFS family