confers_resistance_to_antibiotic derives_from confers_resistance_to_antibiotic cycloheximide Saccharomyces cerevisiae ACT1 with mutations conferring resistance to cycloheximide ARO:3009326 ACT1 in eukaryotes fungi is associated with actin in the cytoskeletal structure. It should not be confused with ACT genes responsible for bacterial functions like beta lactamase activity. Mutations in eukaryotic ACT1 can cause conformational changes to cellular structure and can result in resistance against several compounds. antibiotic_resistance antifungal susceptible actin antifungal resistant actin