confers_resistance_to_antibiotic derives_from confers_resistance_to_antibiotic fluconazole antifungal-susceptible beta-1,3-glucan synthase azole resistant beta-1,3-glucan synthase Candida glabrata FKS1 with mutations conferring resistance to fluconazole antibiotic_resistance Nakaseomyces glabratus ARO:3009422 Mutations in FKS2 are associated with modifications of the beta glucan in the fungal cell wall. As such, these mutations typically showcase increased resistance against echinocandin drugs. However, some studies have reported that some FKS2 mutations can result in increased resistance against azole drugs as well.