primary amebic meningoencephalitis granulomatous amebic encephalitis A parasitic protozoa infectious disease that results in infection of the brain caused by Acanthamoeba or Balamuthia mandrillaris. The symptoms include headaches, altered mental status, and focal neurologic deficit, which progresses over several weeks to death. Acanthamoeba granulomatous encephalitis GARD:12651 DOID:0050246 Acanthamoeba encephalitis disease_ontology Granulomatous Amebic Encephalitis due to Acanthamoeba granulomatous amoebic encephalitis brain disease