alcohol dependence lschriml 2012-09-05T11:48:42Z OMIM:103780 DOID:0050741 EFO:0003829 A substance dependence that is characterized by tolerance, withdrawal symptoms, increasing use, persistent desire to decrease consumption, time spent obtaining or recovering from alcohol caused by a physical and psychological dependence on alcohol. disease_ontology KEGG:05034 SNOMEDCT_US_2020_03_01:66590003 alcoholism substance dependence