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    <!-- http://purl.obolibrary.org/obo/DOID_12177 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/DOID_12177">
        <rdfs:label>common variable immunodeficiency</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_2583"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/DOID_417"/>
        <oboInOwl:id>DOID:12177</oboInOwl:id>
        <oboInOwl:hasDbXref>OMIM:614699</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:615767</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:240500</oboInOwl:hasDbXref>
        <ns2:IAO_0000115>An agammaglobulinemia that is results in insufficient production of antibodies needed to respond to exposure of pathogens and is characterized by low Ig levels with phenotypically normal B cells that can proliferate but do not develop into Ig-producing cells.</ns2:IAO_0000115>
        <oboInOwl:hasDbXref>UMLS_CUI:C0009447</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ICD10CM:D83</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:607594</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GARD:6140</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:613493</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MESH:D017074</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:613494</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:613495</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>disease_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>OMIM:613496</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>SNOMEDCT_US_2020_03_01:191010004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:615577</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>OMIM:614700</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">CVID</oboInOwl:hasExactSynonym>
        <rdfs:comment>Xref MGI.
OMIM mapping confirmed by DO. [SN].</rdfs:comment>
        <oboInOwl:hasDbXref>ICD9CM:279.06</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ORDO:1572</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym xml:lang="en">acquired agammaglobulinemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">acquired hypogammaglobulinemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">common variable agammaglobulinemia</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym xml:lang="en">sporadic hypogammaglobulinemia</oboInOwl:hasExactSynonym>
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        <rdfs:label>agammaglobulinemia</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/DOID_417 -->

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        <rdfs:label>autoimmune disease</rdfs:label>
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