autosomal genetic disease hypophosphatasia SNOMEDCT_US_2020_03_01:30174008 NCI:C26798 GARD:6734 SNOMEDCT_US_2020_03_01:70848009 DOID:14213 disease_ontology DOID:14763 A syndrome characterized by disruption of mineralization of bones and teeth that has_material_basis_in mutation in ALPL on chromosome 1p36.12. ORDO:436 MESH:C562440 UMLS_CUI:C0020630 OMIM mapping confirmed by DO. [SN]. ICD10CM:E83.39 MESH:D007014 UMLS_CUI:C0220743 childhood hypophosphatasia deficiency of alkaline phosphatase hypophospatasia, childhood syndrome