regulation of membrane potential positive regulation of membrane potential Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane. GO:0045838 activation of membrane potential biological_process elevation of membrane potential stimulation of membrane potential up regulation of membrane potential up-regulation of membrane potential upregulation of membrane potential