<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/BCGO?iri=http://purl.obolibrary.org/obo/BCGO_9000222"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns2="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000118"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000119"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/BCGO_0000002 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/BCGO_0000002">
        <rdfs:label xml:lang="en">mouse strain</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/BCGO_9000222 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/BCGO_9000222">
        <rdfs:label xml:lang="en">Neurog3{tm2(EGFP)Ggr} mouse strain</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/BCGO_0000002"/>
        <ns2:IAO_0000115 xml:lang="en">A mouse strain in which the targeted gene, Neurogenin 3 (NCBI Gene ID: 11925), has been modified (allele type: Other) to targeted mutation 2 (MGI ID: Neurog3{tm2(EGFP)Ggr). A targeting construct was designed to insert an IRES-EGFP and a floxed puro downstream of the coding sequence. Crossing with mice expressing Cre in the germ line excised the puromycin resistance gene. Homozygous mice express Ngn3 protein, do not develop diabetes and behave like wild-types. Ngn3-positive cells are labeled with EGFP and can be purified by FACS.</ns2:IAO_0000115>
        <ns2:IAO_0000118 xml:lang="en">Neurog3{tm2(EGFP)Ggr}</ns2:IAO_0000118>
        <ns2:IAO_0000117 xml:lang="en">Person: Mark A. Magnuson, Jill Lindner, Jean-Philippe Cartailler</ns2:IAO_0000117>
        <ns2:IAO_0000119 xml:lang="en">Vanderbilt University Medical Center</ns2:IAO_0000119>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



